-- dump date   	20140618_184835
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
926570000001	plasmid partitioning protein RepA; Region: partition_RepA; TIGR03453
926570000002	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
926570000003	DNA binding residues [nucleotide binding]
926570000004	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570000005	P-loop; other site
926570000006	Magnesium ion binding site [ion binding]; other site
926570000007	transport-energizing ATPase, TRC40/GET3/ArsA family; Region: GET3_arsA_TRC40; TIGR00345
926570000008	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570000009	Magnesium ion binding site [ion binding]; other site
926570000010	plasmid partitioning protein RepB; Region: partition_RepB; TIGR03454
926570000011	ParB-like nuclease domain; Region: ParB; smart00470
926570000012	Cre recombinase, C-terminal catalytic domain. Cre-like recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre...; Region: INT_Cre; cd00799
926570000013	DNA binding site [nucleotide binding]
926570000014	dimer interface [polypeptide binding]; other site
926570000015	active site
926570000016	Int/Topo IB signature motif; other site
926570000017	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
926570000018	homodimer interface [polypeptide binding]; other site
926570000019	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570000020	catalytic residue [active]
926570000021	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000022	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570000023	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570000024	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570000025	metal binding site [ion binding]; metal-binding site
926570000026	active site
926570000027	I-site; other site
926570000028	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570000029	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
926570000030	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000031	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000032	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570000033	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570000034	DNA binding site [nucleotide binding]
926570000035	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570000036	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926570000037	metal-binding site [ion binding]
926570000038	putative mercuric reductase; Provisional; Region: PRK14727
926570000039	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570000040	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926570000041	Helix-Turn-Helix DNA binding domain of the CadR- and PbrR-like transcription regulators; Region: HTH_CadR-PbrR-like; cd04785
926570000042	DNA binding residues [nucleotide binding]
926570000043	Hg(II)-responsive transcriptional regulator; Region: MerR; TIGR02051
926570000044	dimer interface [polypeptide binding]; other site
926570000045	putative metal binding site [ion binding]; other site
926570000046	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000047	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000048	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
926570000049	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
926570000050	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570000051	ATP binding site [chemical binding]; other site
926570000052	putative Mg++ binding site [ion binding]; other site
926570000053	HipA N-terminal domain; Region: Couple_hipA; cl11853
926570000054	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570000055	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570000056	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000057	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000058	HipA-like N-terminal domain; Region: HipA_N; pfam07805
926570000059	HipA-like C-terminal domain; Region: HipA_C; pfam07804
926570000060	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
926570000061	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
926570000062	Uncharacterized conserved protein [Function unknown]; Region: COG0398
926570000063	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
926570000064	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
926570000065	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
926570000066	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000067	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000068	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000069	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
926570000070	active site
926570000071	LssY C-terminus; Region: LssY_C; pfam14067
926570000072	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
926570000073	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570000074	active site
926570000075	phosphorylation site [posttranslational modification]
926570000076	intermolecular recognition site; other site
926570000077	dimerization interface [polypeptide binding]; other site
926570000078	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570000079	DNA binding site [nucleotide binding]
926570000080	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
926570000081	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926570000082	dimerization interface [polypeptide binding]; other site
926570000083	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570000084	dimer interface [polypeptide binding]; other site
926570000085	phosphorylation site [posttranslational modification]
926570000086	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570000087	ATP binding site [chemical binding]; other site
926570000088	Mg2+ binding site [ion binding]; other site
926570000089	G-X-G motif; other site
926570000090	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
926570000091	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
926570000092	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
926570000093	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
926570000094	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570000095	Protein of unknown function (DUF3095); Region: DUF3095; pfam11294
926570000096	MULE transposase domain; Region: MULE; pfam10551
926570000097	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570000098	dimerization interface [polypeptide binding]; other site
926570000099	putative DNA binding site [nucleotide binding]; other site
926570000100	putative Zn2+ binding site [ion binding]; other site
926570000101	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926570000102	active site residue [active]
926570000103	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
926570000104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570000105	putative substrate translocation pore; other site
926570000106	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570000107	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926570000108	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
926570000109	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570000110	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
926570000111	Precorrin-6A synthase, the cobalamin biosynthesis enzyme CobF; Region: Precorrin-6A-synthase; cd11643
926570000112	active site
926570000113	SAM binding site [chemical binding]; other site
926570000114	homodimer interface [polypeptide binding]; other site
926570000115	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
926570000116	active site
926570000117	SAM binding site [chemical binding]; other site
926570000118	homodimer interface [polypeptide binding]; other site
926570000119	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
926570000120	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
926570000121	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
926570000122	conserved cys residue [active]
926570000123	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
926570000124	active site
926570000125	SAM binding site [chemical binding]; other site
926570000126	homodimer interface [polypeptide binding]; other site
926570000127	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
926570000128	active site
926570000129	putative homodimer interface [polypeptide binding]; other site
926570000130	SAM binding site [chemical binding]; other site
926570000131	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
926570000132	precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Region: CbiT; TIGR02469
926570000133	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; pfam02571
926570000134	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
926570000135	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
926570000136	active site
926570000137	SAM binding site [chemical binding]; other site
926570000138	homodimer interface [polypeptide binding]; other site
926570000139	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
926570000140	active site
926570000141	SAM binding site [chemical binding]; other site
926570000142	homodimer interface [polypeptide binding]; other site
926570000143	precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285
926570000144	Precorrin-8X methylmutase; Region: CbiC; pfam02570
926570000145	precorrin-3B synthase; Region: CobG; TIGR02435
926570000146	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
926570000147	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK12321
926570000148	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
926570000149	cobalamin biosynthesis protein CobW; Region: CobW; TIGR02475
926570000150	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
926570000151	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
926570000152	Protein of unknown function (DUF1636); Region: DUF1636; pfam07845
926570000153	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
926570000154	cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Validated; Region: PRK05986
926570000155	cobyric acid synthase; Provisional; Region: PRK00784
926570000156	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
926570000157	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
926570000158	catalytic triad [active]
926570000159	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926570000160	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
926570000161	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570000162	catalytic residue [active]
926570000163	Subfamily of the nitroreductase family that includes BluB protein in Rhodobacter capsulatus is involved in the conversion of cobinamide to cobalamin in Cobalamin (vitamin B12) biosynthesis. Nitroreductases typically reduce their substrates by using NAD(P)...; Region: BluB; cd02145
926570000164	putative FMN binding site [chemical binding]; other site
926570000165	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
926570000166	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
926570000167	catalytic core [active]
926570000168	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
926570000169	homotrimer interface [polypeptide binding]; other site
926570000170	Walker A motif; other site
926570000171	GTP binding site [chemical binding]; other site
926570000172	Walker B motif; other site
926570000173	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
926570000174	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
926570000175	putative dimer interface [polypeptide binding]; other site
926570000176	active site pocket [active]
926570000177	putative cataytic base [active]
926570000178	Cobalamin-5-phosphate synthase; Region: CobS; cl00415
926570000179	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
926570000180	domain IV; other site
926570000181	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
926570000182	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
926570000183	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
926570000184	dimer interface [polypeptide binding]; other site
926570000185	ssDNA binding site [nucleotide binding]; other site
926570000186	tetramer (dimer of dimers) interface [polypeptide binding]; other site
926570000187	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
926570000188	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000189	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000190	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
926570000191	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570000192	non-specific DNA binding site [nucleotide binding]; other site
926570000193	salt bridge; other site
926570000194	sequence-specific DNA binding site [nucleotide binding]; other site
926570000195	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
926570000196	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570000197	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570000198	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000199	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000200	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570000201	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570000202	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570000203	catalytic residues [active]
926570000204	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570000205	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570000206	Synaptic Site I dimer interface [polypeptide binding]; other site
926570000207	DNA binding site [nucleotide binding]
926570000208	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
926570000209	DNA-binding interface [nucleotide binding]; DNA binding site
926570000210	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570000211	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570000212	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000213	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000214	potential frameshift: common BLAST hit: gi|148243732|ref|YP_001219972.1| transposase, IS4 family protein
926570000215	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570000216	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570000217	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570000218	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570000219	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570000220	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570000221	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570000222	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570000223	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
926570000224	short chain dehydrogenase; Provisional; Region: PRK06198
926570000225	classical (c) SDRs; Region: SDR_c; cd05233
926570000226	NAD(P) binding site [chemical binding]; other site
926570000227	active site
926570000228	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570000229	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
926570000230	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926570000231	dimer interface [polypeptide binding]; other site
926570000232	PYR/PP interface [polypeptide binding]; other site
926570000233	TPP binding site [chemical binding]; other site
926570000234	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926570000235	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926570000236	TPP-binding site [chemical binding]; other site
926570000237	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570000238	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570000239	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570000240	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
926570000241	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
926570000242	tetramerization interface [polypeptide binding]; other site
926570000243	NAD(P) binding site [chemical binding]; other site
926570000244	catalytic residues [active]
926570000245	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
926570000246	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926570000247	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
926570000248	ligand binding site [chemical binding]; other site
926570000249	NAD binding site [chemical binding]; other site
926570000250	dimerization interface [polypeptide binding]; other site
926570000251	catalytic site [active]
926570000252	DDE domain; Region: DDE_Tnp_IS240; pfam13610
926570000253	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
926570000254	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
926570000255	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
926570000256	putative active site [active]
926570000257	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570000258	short chain dehydrogenase; Provisional; Region: PRK06198
926570000259	classical (c) SDRs; Region: SDR_c; cd05233
926570000260	NAD(P) binding site [chemical binding]; other site
926570000261	active site
926570000262	2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514
926570000263	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926570000264	DNA binding site [nucleotide binding]
926570000265	domain linker motif; other site
926570000266	Periplasmic sugar-binding domain of uncharacterized transport systems; Region: PBP1_uncharacterized_sugar_binding; cd06307
926570000267	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570000268	putative ligand binding site [chemical binding]; other site
926570000269	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570000270	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926570000271	DNA interaction; other site
926570000272	Metal-binding active site; metal-binding site
926570000273	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570000274	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570000275	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570000276	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
926570000277	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_4; cd06312
926570000278	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570000279	putative ligand binding site [chemical binding]; other site
926570000280	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570000281	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570000282	TM-ABC transporter signature motif; other site
926570000283	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570000284	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570000285	Walker A/P-loop; other site
926570000286	ATP binding site [chemical binding]; other site
926570000287	Q-loop/lid; other site
926570000288	ABC transporter signature motif; other site
926570000289	Walker B; other site
926570000290	D-loop; other site
926570000291	H-loop/switch region; other site
926570000292	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926570000293	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926570000294	substrate binding site [chemical binding]; other site
926570000295	ATP binding site [chemical binding]; other site
926570000296	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
926570000297	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
926570000298	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
926570000299	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926570000300	PYR/PP interface [polypeptide binding]; other site
926570000301	dimer interface [polypeptide binding]; other site
926570000302	TPP binding site [chemical binding]; other site
926570000303	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926570000304	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926570000305	TPP-binding site [chemical binding]; other site
926570000306	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
926570000307	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570000308	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
926570000309	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
926570000310	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
926570000311	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
926570000312	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
926570000313	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000314	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000315	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000316	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
926570000317	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
926570000318	Transposase; Region: HTH_Tnp_1; pfam01527
926570000319	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
926570000320	IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483
926570000321	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570000322	Walker A motif; other site
926570000323	ATP binding site [chemical binding]; other site
926570000324	Walker B motif; other site
926570000325	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570000326	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000327	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000328	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000329	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926570000330	DNA binding residues [nucleotide binding]
926570000331	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570000332	Integrase core domain; Region: rve; pfam00665
926570000333	Transposase domain (DUF772); Region: DUF772; pfam05598
926570000334	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570000335	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
926570000336	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570000337	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570000338	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570000339	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570000340	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
926570000341	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570000342	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570000343	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570000344	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570000345	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570000346	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570000347	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926570000348	DNA interaction; other site
926570000349	Metal-binding active site; metal-binding site
926570000350	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
926570000351	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
926570000352	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570000353	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
926570000354	[2Fe-2S] cluster binding site [ion binding]; other site
926570000355	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
926570000356	This CD includes the putative hydrocarbon oxygenase, MocD, a bacterial rhizopine (3-O-methyl-scyllo-inosamine, 3-O-MSI) oxygenase, and other related proteins. It has been proposed that MocD, MocE (Rieske-like ferredoxin), and MocF (ferredoxin reductase)...; Region: Rhizopine-oxygenase-like; cd03511
926570000357	putative di-iron ligands [ion binding]; other site
926570000358	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
926570000359	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926570000360	DNA binding site [nucleotide binding]
926570000361	domain linker motif; other site
926570000362	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926570000363	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570000364	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
926570000365	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570000366	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570000367	catalytic residue [active]
926570000368	TrbC/VIRB2 family; Region: TrbC; pfam04956
926570000369	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
926570000370	type IV secretion system protein VirB4; Provisional; Region: PRK13853
926570000371	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
926570000372	P-type DNA transfer protein VirB5; Region: VirB5; TIGR02791
926570000373	Type IV secretion system proteins; Region: T4SS; pfam07996
926570000374	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
926570000375	VirB8 protein; Region: VirB8; cl01500
926570000376	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
926570000377	VirB7 interaction site; other site
926570000378	Bacterial conjugation TrbI-like protein; Region: TrbI; cl04242
926570000379	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570000380	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000381	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000382	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000383	type IV secretion system protein VirB11; Provisional; Region: PRK13851
926570000384	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
926570000385	Walker A motif; other site
926570000386	hexamer interface [polypeptide binding]; other site
926570000387	ATP binding site [chemical binding]; other site
926570000388	Walker B motif; other site
926570000389	conjugal transfer coupling protein TraG; Provisional; Region: PRK13822
926570000390	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
926570000391	Walker A motif; other site
926570000392	ATP binding site [chemical binding]; other site
926570000393	Walker B motif; other site
926570000394	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926570000395	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
926570000396	AsnC family; Region: AsnC_trans_reg; pfam01037
926570000397	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
926570000398	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
926570000399	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570000400	catalytic residue [active]
926570000401	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
926570000402	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
926570000403	metal binding site [ion binding]; metal-binding site
926570000404	putative dimer interface [polypeptide binding]; other site
926570000405	allantoate amidohydrolase; Reviewed; Region: PRK12890
926570000406	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
926570000407	active site
926570000408	metal binding site [ion binding]; metal-binding site
926570000409	dimer interface [polypeptide binding]; other site
926570000410	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
926570000411	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
926570000412	active site
926570000413	DNA binding site [nucleotide binding]
926570000414	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
926570000415	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
926570000416	Catalytic site [active]
926570000417	Uncharacterized conserved protein [Function unknown]; Region: COG2135
926570000418	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000419	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000420	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000421	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000422	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
926570000423	Ribosomal protein S13/S18; Region: Ribosomal_S13; cl00331
926570000424	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570000425	Walker A motif; other site
926570000426	ATP binding site [chemical binding]; other site
926570000427	Helicase; Region: Helicase_RecD; pfam05127
926570000428	Family description; Region: UvrD_C_2; pfam13538
926570000429	Toprim domain; Region: Toprim_3; pfam13362
926570000430	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
926570000431	Ti-type conjugative transfer relaxase TraA; Region: TraA_Ti; TIGR02768
926570000432	AAA domain; Region: AAA_30; pfam13604
926570000433	conjugal transfer protein TraL; Provisional; Region: PRK13886
926570000434	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
926570000435	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570000436	active site
926570000437	phosphorylation site [posttranslational modification]
926570000438	intermolecular recognition site; other site
926570000439	ANTAR domain; Region: ANTAR; pfam03861
926570000440	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
926570000441	NMT1-like family; Region: NMT1_2; pfam13379
926570000442	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000443	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000444	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000445	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
926570000446	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570000447	putative substrate translocation pore; other site
926570000448	NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251
926570000449	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570000450	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
926570000451	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
926570000452	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
926570000453	Small subunit of nitrite reductase (NirD) family, Rieske domain; composed of proteins similar to the Bacillus subtilis small subunit of assimilatory nitrite reductase containing a Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain...; Region: Rieske_NirD_small_Bacillus; cd03530
926570000454	[2Fe-2S] cluster binding site [ion binding]; other site
926570000455	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
926570000456	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
926570000457	[4Fe-4S] binding site [ion binding]; other site
926570000458	molybdopterin cofactor binding site; other site
926570000459	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
926570000460	molybdopterin cofactor binding site; other site
926570000461	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
926570000462	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
926570000463	active site
926570000464	SAM binding site [chemical binding]; other site
926570000465	homodimer interface [polypeptide binding]; other site
926570000466	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
926570000467	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570000468	non-specific DNA binding site [nucleotide binding]; other site
926570000469	salt bridge; other site
926570000470	sequence-specific DNA binding site [nucleotide binding]; other site
926570000471	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
926570000472	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570000473	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570000474	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000475	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000476	multiple promoter invertase; Provisional; Region: mpi; PRK13413
926570000477	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570000478	catalytic residues [active]
926570000479	catalytic nucleophile [active]
926570000480	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570000481	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570000482	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570000483	Synaptic Site I dimer interface [polypeptide binding]; other site
926570000484	DNA binding site [nucleotide binding]
926570000485	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570000486	DNA-binding interface [nucleotide binding]; DNA binding site
926570000487	DDE superfamily endonuclease; Region: DDE_5; cl17874
926570000488	Transposase domain (DUF772); Region: DUF772; pfam05598
926570000489	SNF2 Helicase protein; Region: DUF3670; pfam12419
926570000490	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
926570000491	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570000492	ATP binding site [chemical binding]; other site
926570000493	putative Mg++ binding site [ion binding]; other site
926570000494	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570000495	nucleotide binding region [chemical binding]; other site
926570000496	ATP-binding site [chemical binding]; other site
926570000497	Uncharacterized conserved protein [Function unknown]; Region: COG4279
926570000498	SWIM zinc finger; Region: SWIM; pfam04434
926570000499	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570000500	non-specific DNA binding site [nucleotide binding]; other site
926570000501	salt bridge; other site
926570000502	sequence-specific DNA binding site [nucleotide binding]; other site
926570000503	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
926570000504	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570000505	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
926570000506	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
926570000507	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000508	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570000509	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
926570000510	Transposase domain (DUF772); Region: DUF772; pfam05598
926570000511	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570000512	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
926570000513	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570000514	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000515	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000516	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
926570000517	Ribbon-helix-helix domain; Region: RHH_3; pfam12651
926570000518	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570000519	dimer interface [polypeptide binding]; other site
926570000520	phosphorylation site [posttranslational modification]
926570000521	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
926570000522	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570000523	ATP binding site [chemical binding]; other site
926570000524	Mg2+ binding site [ion binding]; other site
926570000525	G-X-G motif; other site
926570000526	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
926570000527	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570000528	active site
926570000529	phosphorylation site [posttranslational modification]
926570000530	intermolecular recognition site; other site
926570000531	dimerization interface [polypeptide binding]; other site
926570000532	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570000533	Walker A motif; other site
926570000534	ATP binding site [chemical binding]; other site
926570000535	Walker B motif; other site
926570000536	arginine finger; other site
926570000537	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570000538	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
926570000539	Recombinase; Region: Recombinase; pfam07508
926570000540	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
926570000541	potential frameshift: common BLAST hit: gi|148259801|ref|YP_001233928.1| transposase, mutator type
926570000542	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570000543	MULE transposase domain; Region: MULE; pfam10551
926570000544	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570000545	transposase; Validated; Region: PRK08181
926570000546	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570000547	Walker A motif; other site
926570000548	ATP binding site [chemical binding]; other site
926570000549	Walker B motif; other site
926570000550	Integrase core domain; Region: rve; pfam00665
926570000551	Fic/DOC family; Region: Fic; cl00960
926570000552	VbhA antitoxin and related proteins; Region: VbhA_like; cd11586
926570000553	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
926570000554	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
926570000555	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
926570000556	pAE1 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal domain. This CD includes various bacterial integrases, including the predicted integrase of the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus...; Region: INT_pAE1; cd01188
926570000557	Int/Topo IB signature motif; other site
926570000558	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
926570000559	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570000560	active site
926570000561	DNA binding site [nucleotide binding]
926570000562	Int/Topo IB signature motif; other site
926570000563	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
926570000564	INT_SG5, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 5, N- and C-terminal domains. The CD contains mainly predicted bacterial integrase/recombinases; Region: INT_SG5; cd01190
926570000565	Int/Topo IB signature motif; other site
926570000566	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
926570000567	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
926570000568	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570000569	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570000570	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
926570000571	dimerization interface [polypeptide binding]; other site
926570000572	substrate binding pocket [chemical binding]; other site
926570000573	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570000574	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
926570000575	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570000576	substrate binding site [chemical binding]; other site
926570000577	trimer interface [polypeptide binding]; other site
926570000578	oxyanion hole (OAH) forming residues; other site
926570000579	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
926570000580	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926570000581	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901
926570000582	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
926570000583	Integrase core domain; Region: rve_3; pfam13683
926570000584	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
926570000585	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000586	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000587	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
926570000588	NIPSNAP; Region: NIPSNAP; pfam07978
926570000589	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
926570000590	Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like; Region: ALDH_DhaS; cd07114
926570000591	NAD(P) binding site [chemical binding]; other site
926570000592	catalytic residues [active]
926570000593	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
926570000594	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
926570000595	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000596	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000597	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000598	Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296
926570000599	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
926570000600	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
926570000601	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
926570000602	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
926570000603	TAP-like protein; Region: Abhydrolase_4; pfam08386
926570000604	Amino acid synthesis; Region: AA_synth; pfam06684
926570000605	Transcriptional regulators [Transcription]; Region: GntR; COG1802
926570000606	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570000607	DNA-binding site [nucleotide binding]; DNA binding site
926570000608	FCD domain; Region: FCD; pfam07729
926570000609	Transposase domain (DUF772); Region: DUF772; pfam05598
926570000610	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
926570000611	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
926570000612	Integrase core domain; Region: rve; pfam00665
926570000613	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
926570000614	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
926570000615	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926570000616	Coenzyme A binding pocket [chemical binding]; other site
926570000617	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
926570000618	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
926570000619	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
926570000620	INT_SG5, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 5, N- and C-terminal domains. The CD contains mainly predicted bacterial integrase/recombinases; Region: INT_SG5; cd01190
926570000621	Int/Topo IB signature motif; other site
926570000622	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
926570000623	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570000624	active site
926570000625	DNA binding site [nucleotide binding]
926570000626	Int/Topo IB signature motif; other site
926570000627	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
926570000628	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
926570000629	pAE1 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal domain. This CD includes various bacterial integrases, including the predicted integrase of the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus...; Region: INT_pAE1; cd01188
926570000630	Int/Topo IB signature motif; other site
926570000631	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
926570000632	VbhA antitoxin and related proteins; Region: VbhA_like; cd11586
926570000633	FIC domain binding interface [polypeptide binding]; other site
926570000634	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
926570000635	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
926570000636	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570000637	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570000638	catalytic residues [active]
926570000639	catalytic nucleophile [active]
926570000640	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570000641	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570000642	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570000643	Synaptic Site I dimer interface [polypeptide binding]; other site
926570000644	DNA binding site [nucleotide binding]
926570000645	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570000646	DNA-binding interface [nucleotide binding]; DNA binding site
926570000647	PIN domain of the VapC-like UPF0110 protein Mb0640 and homologs; Region: PIN_UPF0110; cd09871
926570000648	putative active site [active]
926570000649	Rv0623-like transcription factor; Region: PSK_trans_fac; pfam07704
926570000650	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926570000651	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
926570000652	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
926570000653	replication initiation protein RepC; Provisional; Region: PRK13824
926570000654	Replication protein C N-terminal domain; Region: RP-C; pfam03428
926570000655	Replication protein C C-terminal region; Region: RP-C_C; pfam11800
926570000656	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
926570000657	RES domain; Region: RES; smart00953
926570000658	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
926570000659	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000660	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000661	replication initiation protein RepC; Provisional; Region: PRK13824
926570000662	Replication protein C N-terminal domain; Region: RP-C; pfam03428
926570000663	Replication protein C C-terminal region; Region: RP-C_C; pfam11800
926570000664	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901
926570000665	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000666	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000667	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570000668	MgtC family; Region: MgtC; pfam02308
926570000669	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
926570000670	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
926570000671	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
926570000672	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
926570000673	putative metal binding site [ion binding]; other site
926570000674	putative homodimer interface [polypeptide binding]; other site
926570000675	putative homotetramer interface [polypeptide binding]; other site
926570000676	putative homodimer-homodimer interface [polypeptide binding]; other site
926570000677	putative allosteric switch controlling residues; other site
926570000678	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570000679	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570000680	catalytic residues [active]
926570000681	catalytic nucleophile [active]
926570000682	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570000683	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570000684	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570000685	Synaptic Site I dimer interface [polypeptide binding]; other site
926570000686	DNA binding site [nucleotide binding]
926570000687	Transposase domain (DUF772); Region: DUF772; pfam05598
926570000688	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
926570000689	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
926570000690	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926570000691	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926570000692	Walker A/P-loop; other site
926570000693	ATP binding site [chemical binding]; other site
926570000694	Q-loop/lid; other site
926570000695	ABC transporter signature motif; other site
926570000696	Walker B; other site
926570000697	D-loop; other site
926570000698	H-loop/switch region; other site
926570000699	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926570000700	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926570000701	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926570000702	Walker A/P-loop; other site
926570000703	ATP binding site [chemical binding]; other site
926570000704	Q-loop/lid; other site
926570000705	ABC transporter signature motif; other site
926570000706	Walker B; other site
926570000707	D-loop; other site
926570000708	H-loop/switch region; other site
926570000709	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926570000710	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926570000711	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570000712	dimer interface [polypeptide binding]; other site
926570000713	conserved gate region; other site
926570000714	ABC-ATPase subunit interface; other site
926570000715	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926570000716	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570000717	dimer interface [polypeptide binding]; other site
926570000718	conserved gate region; other site
926570000719	putative PBP binding loops; other site
926570000720	ABC-ATPase subunit interface; other site
926570000721	The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold; Region: PBP2_clavulanate_OppA2; cd08506
926570000722	peptide binding site [polypeptide binding]; other site
926570000723	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926570000724	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
926570000725	Predicted DNA-binding protein with an HTH domain [General function prediction only]; Region: COG4710
926570000726	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
926570000727	oligomeric interface; other site
926570000728	putative active site [active]
926570000729	homodimer interface [polypeptide binding]; other site
926570000730	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
926570000731	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926570000732	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926570000733	TrwC relaxase; Region: TrwC; pfam08751
926570000734	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
926570000735	AAA domain; Region: AAA_30; pfam13604
926570000736	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
926570000737	putative active site [active]
926570000738	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
926570000739	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570000740	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
926570000741	catalytic residues [active]
926570000742	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
926570000743	Homeodomain-like domain; Region: HTH_23; pfam13384
926570000744	Anaerobic ribonucleoside-triphosphate reductase; Region: NRDD; pfam13597
926570000745	Class III ribonucleotide reductase; Region: RNR_III; cd01675
926570000746	effector binding site; other site
926570000747	active site
926570000748	Zn binding site [ion binding]; other site
926570000749	glycine loop; other site
926570000750	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG2; TIGR02495
926570000751	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570000752	FeS/SAM binding site; other site
926570000753	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570000754	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000755	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000756	CitB domain protein; Region: CitB; TIGR02484
926570000757	Cytochrome c2 [Energy production and conversion]; Region: COG3474
926570000758	potential frameshift: common BLAST hit: gi|82701751|ref|YP_411317.1| putative cytochrome c1 signal peptide protein
926570000759	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570000760	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000761	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570000762	SCP-2 sterol transfer family; Region: SCP2; cl01225
926570000763	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
926570000764	Peptidase family U32; Region: Peptidase_U32; pfam01136
926570000765	putative protease; Provisional; Region: PRK15447
926570000766	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
926570000767	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.   The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_5; cd06153
926570000768	homotrimer interaction site [polypeptide binding]; other site
926570000769	putative active site [active]
926570000770	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
926570000771	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
926570000772	active site
926570000773	multimer interface [polypeptide binding]; other site
926570000774	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
926570000775	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
926570000776	predicted active site [active]
926570000777	catalytic triad [active]
926570000778	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
926570000779	catalytic nucleophile [active]
926570000780	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926570000781	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
926570000782	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
926570000783	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
926570000784	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
926570000785	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
926570000786	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
926570000787	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926570000788	Transposase; Region: HTH_Tnp_1; cl17663
926570000789	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
926570000790	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
926570000791	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570000792	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570000793	catalytic residues [active]
926570000794	catalytic nucleophile [active]
926570000795	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570000796	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570000797	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570000798	Synaptic Site I dimer interface [polypeptide binding]; other site
926570000799	DNA binding site [nucleotide binding]
926570000800	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570000801	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570000802	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926570000803	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570000804	P-loop; other site
926570000805	Magnesium ion binding site [ion binding]; other site
926570000806	replication initiation protein RepC; Provisional; Region: PRK13824
926570000807	Replication protein C N-terminal domain; Region: RP-C; pfam03428
926570000808	Replication protein C C-terminal region; Region: RP-C_C; pfam11800
926570000809	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926570000810	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570000811	P-loop; other site
926570000812	Magnesium ion binding site [ion binding]; other site
926570000813	conjugal transfer relaxase TraI; Provisional; Region: PRK13878
926570000814	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
926570000815	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
926570000816	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
926570000817	ATP binding site [chemical binding]; other site
926570000818	substrate interface [chemical binding]; other site
926570000819	Prokaryotic E2 family E; Region: Prok-E2_E; pfam14462
926570000820	Bacterial multiubiquitin; Region: Bac_multiUb; pfam14452
926570000821	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570000822	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570000823	sequence-specific DNA binding site [nucleotide binding]; other site
926570000824	salt bridge; other site
926570000825	Domain of unknown function (DUF955); Region: DUF955; cl01076
926570000826	HNH endonuclease; Region: HNH_5; pfam14279
926570000827	multiple promoter invertase; Provisional; Region: mpi; PRK13413
926570000828	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570000829	catalytic residues [active]
926570000830	catalytic nucleophile [active]
926570000831	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570000832	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570000833	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570000834	Synaptic Site I dimer interface [polypeptide binding]; other site
926570000835	DNA binding site [nucleotide binding]
926570000836	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570000837	DNA-binding interface [nucleotide binding]; DNA binding site
926570000838	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
926570000839	DNA methylase; Region: N6_N4_Mtase; cl17433
926570000840	DNA methylase; Region: N6_N4_Mtase; pfam01555
926570000841	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570000842	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570000843	non-specific DNA binding site [nucleotide binding]; other site
926570000844	salt bridge; other site
926570000845	sequence-specific DNA binding site [nucleotide binding]; other site
926570000846	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926570000847	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570000848	P-loop; other site
926570000849	Magnesium ion binding site [ion binding]; other site
926570000850	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570000851	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570000852	catalytic residues [active]
926570000853	catalytic nucleophile [active]
926570000854	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570000855	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570000856	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570000857	Synaptic Site I dimer interface [polypeptide binding]; other site
926570000858	DNA binding site [nucleotide binding]
926570000859	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570000860	DNA-binding interface [nucleotide binding]; DNA binding site
926570000861	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
926570000862	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
926570000863	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570000864	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570000865	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
926570000866	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
926570000867	Predicted transcriptional regulator [Transcription]; Region: COG3905
926570000868	MobA/MobL family; Region: MobA_MobL; pfam03389
926570000869	DnaA N-terminal domain; Region: DnaA_N; pfam11638
926570000870	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
926570000871	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570000872	Walker A motif; other site
926570000873	ATP binding site [chemical binding]; other site
926570000874	Walker B motif; other site
926570000875	arginine finger; other site
926570000876	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
926570000877	DnaA box-binding interface [nucleotide binding]; other site
926570000878	S-formylglutathione hydrolase; Region: PLN02442
926570000879	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
926570000880	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
926570000881	DNA-binding site [nucleotide binding]; DNA binding site
926570000882	RNA-binding motif; other site
926570000883	Helix-Turn-Helix DNA binding domain of the regulatory protein GnyR; Region: HTH_GnyR; cd04776
926570000884	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
926570000885	DNA binding residues [nucleotide binding]
926570000886	putative dimer interface [polypeptide binding]; other site
926570000887	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926570000888	acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930
926570000889	dimer interface [polypeptide binding]; other site
926570000890	active site
926570000891	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
926570000892	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
926570000893	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
926570000894	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
926570000895	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570000896	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
926570000897	substrate binding site [chemical binding]; other site
926570000898	oxyanion hole (OAH) forming residues; other site
926570000899	trimer interface [polypeptide binding]; other site
926570000900	Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418
926570000901	acyl-CoA dehydrogenase; Provisional; Region: PTZ00456
926570000902	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570000903	active site
926570000904	Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806
926570000905	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
926570000906	substrate binding site [chemical binding]; other site
926570000907	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570000908	ABC-ATPase subunit interface; other site
926570000909	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
926570000910	tungstate ABC transporter binding protein WtpA; Region: tungstate_WtpA; TIGR03730
926570000911	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926570000912	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; cl17549
926570000913	TspO/MBR family; Region: TspO_MBR; pfam03073
926570000914	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
926570000915	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
926570000916	GPR1/FUN34/yaaH family; Region: Grp1_Fun34_YaaH; cl00685
926570000917	twin arginine translocase protein A; Provisional; Region: tatA; PRK00720
926570000918	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
926570000919	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
926570000920	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
926570000921	intersubunit interface [polypeptide binding]; other site
926570000922	active site
926570000923	Zn2+ binding site [ion binding]; other site
926570000924	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
926570000925	Cupin domain; Region: Cupin_2; pfam07883
926570000926	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
926570000927	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
926570000928	putative active site [active]
926570000929	catalytic triad [active]
926570000930	putative dimer interface [polypeptide binding]; other site
926570000931	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570000932	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570000933	non-specific DNA binding site [nucleotide binding]; other site
926570000934	salt bridge; other site
926570000935	sequence-specific DNA binding site [nucleotide binding]; other site
926570000936	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
926570000937	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
926570000938	substrate binding site [chemical binding]; other site
926570000939	hexamer interface [polypeptide binding]; other site
926570000940	metal binding site [ion binding]; metal-binding site
926570000941	Heparinase II/III-like protein; Region: Hepar_II_III; cl15421
926570000942	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
926570000943	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
926570000944	NAD binding site [chemical binding]; other site
926570000945	homodimer interface [polypeptide binding]; other site
926570000946	active site
926570000947	substrate binding site [chemical binding]; other site
926570000948	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
926570000949	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570000950	putative ADP-binding pocket [chemical binding]; other site
926570000951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: CreA; COG3045
926570000952	CreA protein; Region: CreA; pfam05981
926570000953	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
926570000954	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
926570000955	purine monophosphate binding site [chemical binding]; other site
926570000956	dimer interface [polypeptide binding]; other site
926570000957	putative catalytic residues [active]
926570000958	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
926570000959	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
926570000960	Uncharacterized conserved protein [Function unknown]; Region: COG2128
926570000961	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
926570000962	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
926570000963	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570000964	Mg2+ binding site [ion binding]; other site
926570000965	G-X-G motif; other site
926570000966	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
926570000967	anchoring element; other site
926570000968	dimer interface [polypeptide binding]; other site
926570000969	ATP binding site [chemical binding]; other site
926570000970	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
926570000971	active site
926570000972	putative metal-binding site [ion binding]; other site
926570000973	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
926570000974	cytidylate kinase; Provisional; Region: cmk; PRK00023
926570000975	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
926570000976	CMP-binding site; other site
926570000977	The sites determining sugar specificity; other site
926570000978	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
926570000979	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
926570000980	hinge; other site
926570000981	active site
926570000982	Protein of unknown function (FYDLN_acid); Region: FYDLN_acid; pfam09538
926570000983	TIGR02300 family protein; Region: FYDLN_acid
926570000984	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
926570000985	CoA-transferase family III; Region: CoA_transf_3; pfam02515
926570000986	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926570000987	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
926570000988	ribonuclease R; Region: RNase_R; TIGR02063
926570000989	RNB domain; Region: RNB; pfam00773
926570000990	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
926570000991	RNA binding site [nucleotide binding]; other site
926570000992	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
926570000993	protein binding site [polypeptide binding]; other site
926570000994	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
926570000995	Catalytic dyad [active]
926570000996	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
926570000997	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
926570000998	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
926570000999	Predicted amidohydrolase [General function prediction only]; Region: COG0388
926570001000	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
926570001001	putative active site [active]
926570001002	catalytic triad [active]
926570001003	putative dimer interface [polypeptide binding]; other site
926570001004	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
926570001005	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
926570001006	Cytochrome c; Region: Cytochrom_C; pfam00034
926570001007	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570001008	active site
926570001009	DNA binding site [nucleotide binding]
926570001010	Int/Topo IB signature motif; other site
926570001011	YqcI/YcgG family; Region: YqcI_YcgG; cl01349
926570001012	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
926570001013	Transposase domain (DUF772); Region: DUF772; pfam05598
926570001014	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570001015	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570001016	Integrase core domain; Region: rve; pfam00665
926570001017	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
926570001018	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570001019	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570001020	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570001021	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570001022	putative substrate translocation pore; other site
926570001023	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570001024	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
926570001025	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570001026	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570001027	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570001028	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570001029	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570001030	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570001031	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570001032	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570001033	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
926570001034	Homeodomain-like domain; Region: HTH_23; cl17451
926570001035	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570001036	Integrase core domain; Region: rve; pfam00665
926570001037	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
926570001038	Transposase domain (DUF772); Region: DUF772; pfam05598
926570001039	5-aminolevulinate synthase; Validated; Region: PRK09064
926570001040	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
926570001041	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570001042	catalytic residue [active]
926570001043	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
926570001044	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570001045	AAA domain; Region: AAA_31; pfam13614
926570001046	P-loop; other site
926570001047	Magnesium ion binding site [ion binding]; other site
926570001048	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926570001049	Uncharacterized conserved protein [Function unknown]; Region: COG0062
926570001050	putative carbohydrate kinase; Provisional; Region: PRK10565
926570001051	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
926570001052	putative substrate binding site [chemical binding]; other site
926570001053	putative ATP binding site [chemical binding]; other site
926570001054	glycine cleavage system aminomethyltransferase T; Provisional; Region: gcvT; PRK13579
926570001055	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
926570001056	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
926570001057	lipoyl attachment site [posttranslational modification]; other site
926570001058	glycine dehydrogenase; Provisional; Region: PRK05367
926570001059	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
926570001060	tetramer interface [polypeptide binding]; other site
926570001061	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570001062	catalytic residue [active]
926570001063	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
926570001064	tetramer interface [polypeptide binding]; other site
926570001065	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570001066	catalytic residue [active]
926570001067	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
926570001068	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
926570001069	tandem repeat interface [polypeptide binding]; other site
926570001070	oligomer interface [polypeptide binding]; other site
926570001071	active site residues [active]
926570001072	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
926570001073	tandem repeat interface [polypeptide binding]; other site
926570001074	oligomer interface [polypeptide binding]; other site
926570001075	active site residues [active]
926570001076	cell division protein MraZ; Reviewed; Region: PRK00326
926570001077	MraZ protein; Region: MraZ; pfam02381
926570001078	MraZ protein; Region: MraZ; pfam02381
926570001079	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
926570001080	MraW methylase family; Region: Methyltransf_5; cl17771
926570001081	Predicted secreted (periplasmic) protein [Function unknown]; Region: COG5462
926570001082	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
926570001083	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
926570001084	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
926570001085	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
926570001086	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
926570001087	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926570001088	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
926570001089	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional; Region: PRK14093
926570001090	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
926570001091	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926570001092	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
926570001093	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
926570001094	Mg++ binding site [ion binding]; other site
926570001095	putative catalytic motif [active]
926570001096	putative substrate binding site [chemical binding]; other site
926570001097	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01390
926570001098	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926570001099	cell division protein FtsW; Region: ftsW; TIGR02614
926570001100	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane]; Region: MurG; COG0707
926570001101	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
926570001102	active site
926570001103	homodimer interface [polypeptide binding]; other site
926570001104	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
926570001105	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
926570001106	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926570001107	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
926570001108	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
926570001109	FAD binding domain; Region: FAD_binding_4; pfam01565
926570001110	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
926570001111	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
926570001112	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
926570001113	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926570001114	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
926570001115	Cell division protein FtsQ; Region: FtsQ; pfam03799
926570001116	Cell division protein FtsA; Region: FtsA; smart00842
926570001117	cell division protein FtsA; Region: ftsA; TIGR01174
926570001118	Cell division protein FtsA; Region: FtsA; pfam14450
926570001119	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
926570001120	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
926570001121	nucleotide binding site [chemical binding]; other site
926570001122	SulA interaction site; other site
926570001123	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
926570001124	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
926570001125	Competence protein; Region: Competence; pfam03772
926570001126	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926570001127	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570001128	active site
926570001129	Bacterial sugar transferase; Region: Bac_transf; pfam02397
926570001130	GtrA-like protein; Region: GtrA; pfam04138
926570001131	Predicted membrane protein [Function unknown]; Region: COG2246
926570001132	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
926570001133	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570001134	catalytic loop [active]
926570001135	iron binding site [ion binding]; other site
926570001136	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926570001137	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570001138	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570001139	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570001140	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
926570001141	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
926570001142	PqqA family; Region: PqqA; cl15372
926570001143	pyrroloquinoline quinone biosynthesis protein PqqB; Provisional; Region: PRK05184
926570001144	coenzyme PQQ biosynthesis protein B; Region: PQQ_syn_pqqB; TIGR02108
926570001145	pyrroloquinoline quinone biosynthesis protein PqqC; Provisional; Region: PRK05157
926570001146	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; pfam05402
926570001147	pyrroloquinoline quinone biosynthesis protein PqqE; Provisional; Region: PRK05301
926570001148	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570001149	FeS/SAM binding site; other site
926570001150	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
926570001151	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
926570001152	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
926570001153	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
926570001154	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
926570001155	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
926570001156	Isochorismatase family; Region: Isochorismatase; pfam00857
926570001157	catalytic triad [active]
926570001158	metal binding site [ion binding]; metal-binding site
926570001159	conserved cis-peptide bond; other site
926570001160	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
926570001161	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
926570001162	NAD binding site [chemical binding]; other site
926570001163	homotetramer interface [polypeptide binding]; other site
926570001164	homodimer interface [polypeptide binding]; other site
926570001165	active site
926570001166	dihydroxy-acid dehydratase; Provisional; Region: PRK13017
926570001167	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
926570001168	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
926570001169	DNA binding residues [nucleotide binding]
926570001170	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
926570001171	dimer interface [polypeptide binding]; other site
926570001172	copper binding site [ion binding]; other site
926570001173	multidrug efflux protein; Reviewed; Region: PRK09579
926570001174	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
926570001175	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926570001176	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570001177	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
926570001178	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926570001179	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926570001180	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
926570001181	PaaX-like protein; Region: PaaX; pfam07848
926570001182	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
926570001183	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
926570001184	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570001185	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570001186	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570001187	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
926570001188	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
926570001189	MULE transposase domain; Region: MULE; pfam10551
926570001190	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570001191	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570001192	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570001193	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570001194	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570001195	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570001196	aspartate aminotransferase; Provisional; Region: PRK05764
926570001197	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570001198	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570001199	homodimer interface [polypeptide binding]; other site
926570001200	catalytic residue [active]
926570001201	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570001202	TPR motif; other site
926570001203	binding surface
926570001204	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570001205	binding surface
926570001206	TPR motif; other site
926570001207	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
926570001208	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
926570001209	TPR motif; other site
926570001210	binding surface
926570001211	Protein of unknown function (DUF1217); Region: DUF1217; pfam06748
926570001212	Flagellar protein FlbT; Region: FlbT; pfam07378
926570001213	flagellin; Provisional; Region: PRK12807
926570001214	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
926570001215	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
926570001216	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK06008
926570001217	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07521
926570001218	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
926570001219	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
926570001220	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
926570001221	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
926570001222	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
926570001223	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
926570001224	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
926570001225	MarR family; Region: MarR_2; pfam12802
926570001226	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926570001227	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926570001228	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926570001229	squalene-associated FAD-dependent desaturase; Region: HpnE; TIGR03467
926570001230	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
926570001231	active site lid residues [active]
926570001232	substrate binding pocket [chemical binding]; other site
926570001233	catalytic residues [active]
926570001234	substrate-Mg2+ binding site; other site
926570001235	aspartate-rich region 1; other site
926570001236	aspartate-rich region 2; other site
926570001237	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
926570001238	active site lid residues [active]
926570001239	substrate binding pocket [chemical binding]; other site
926570001240	catalytic residues [active]
926570001241	substrate-Mg2+ binding site; other site
926570001242	aspartate-rich region 1; other site
926570001243	aspartate-rich region 2; other site
926570001244	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
926570001245	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
926570001246	DXD motif; other site
926570001247	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
926570001248	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
926570001249	putative NADP binding site [chemical binding]; other site
926570001250	putative substrate binding site [chemical binding]; other site
926570001251	active site
926570001252	Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219
926570001253	Acyltransferase family; Region: Acyl_transf_3; pfam01757
926570001254	Uncharacterized membrane-bound protein [Function unknown]; Region: COG3898
926570001255	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4223
926570001256	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
926570001257	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
926570001258	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
926570001259	domain interfaces; other site
926570001260	active site
926570001261	UGMP family protein; Validated; Region: PRK09604
926570001262	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
926570001263	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
926570001264	homodimer interface [polypeptide binding]; other site
926570001265	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
926570001266	active site pocket [active]
926570001267	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
926570001268	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
926570001269	ligand binding site; other site
926570001270	oligomer interface; other site
926570001271	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
926570001272	dimer interface [polypeptide binding]; other site
926570001273	N-terminal domain interface [polypeptide binding]; other site
926570001274	sulfate 1 binding site; other site
926570001275	glycogen synthase; Provisional; Region: PRK14099
926570001276	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
926570001277	ADP-binding pocket [chemical binding]; other site
926570001278	homodimer interface [polypeptide binding]; other site
926570001279	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
926570001280	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
926570001281	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
926570001282	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926570001283	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570001284	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
926570001285	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926570001286	catalytic core [active]
926570001287	Tim44-like domain; Region: Tim44; pfam04280
926570001288	MltA specific insert domain; Region: MltA; smart00925
926570001289	3D domain; Region: 3D; pfam06725
926570001290	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
926570001291	Cysteine-rich domain; Region: CCG; pfam02754
926570001292	Cysteine-rich domain; Region: CCG; pfam02754
926570001293	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
926570001294	potassium uptake protein; Region: kup; TIGR00794
926570001295	acetyl coenzyme A synthetase (ADP forming), alpha domain; Region: AcCoA-syn-alpha; TIGR02717
926570001296	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
926570001297	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
926570001298	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926570001299	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570001300	Coenzyme A binding pocket [chemical binding]; other site
926570001301	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
926570001302	EamA-like transporter family; Region: EamA; pfam00892
926570001303	EamA-like transporter family; Region: EamA; pfam00892
926570001304	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK07530
926570001305	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
926570001306	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
926570001307	electron transfer flavoprotein subunit alpha; Provisional; Region: PLN00022
926570001308	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
926570001309	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
926570001310	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
926570001311	Ligand binding site [chemical binding]; other site
926570001312	Electron transfer flavoprotein domain; Region: ETF; pfam01012
926570001313	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
926570001314	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
926570001315	metal binding triad; other site
926570001316	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
926570001317	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
926570001318	metal binding triad; other site
926570001319	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
926570001320	catalytic triad [active]
926570001321	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
926570001322	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
926570001323	diiron binding motif [ion binding]; other site
926570001324	Phasin protein; Region: Phasin_2; pfam09361
926570001325	excinuclease ABC subunit B; Provisional; Region: PRK05298
926570001326	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570001327	ATP binding site [chemical binding]; other site
926570001328	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570001329	nucleotide binding region [chemical binding]; other site
926570001330	ATP-binding site [chemical binding]; other site
926570001331	Ultra-violet resistance protein B; Region: UvrB; pfam12344
926570001332	UvrB/uvrC motif; Region: UVR; pfam02151
926570001333	Domain of unknown function (DUF1849); Region: DUF1849; pfam08904
926570001334	Protein of unknown function (DUF983); Region: DUF983; pfam06170
926570001335	Uncharacterized protein family (UPF0262); Region: UPF0262; pfam06793
926570001336	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
926570001337	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
926570001338	Uncharacterized protein conserved in bacteria (DUF2272); Region: DUF2272; pfam10030
926570001339	recombination factor protein RarA; Reviewed; Region: PRK13342
926570001340	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570001341	Walker A motif; other site
926570001342	ATP binding site [chemical binding]; other site
926570001343	Walker B motif; other site
926570001344	arginine finger; other site
926570001345	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
926570001346	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
926570001347	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926570001348	RNA binding surface [nucleotide binding]; other site
926570001349	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
926570001350	active site
926570001351	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
926570001352	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
926570001353	Surface antigen; Region: Bac_surface_Ag; pfam01103
926570001354	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
926570001355	Family of unknown function (DUF490); Region: DUF490; pfam04357
926570001356	enolase; Provisional; Region: eno; PRK00077
926570001357	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
926570001358	dimer interface [polypeptide binding]; other site
926570001359	metal binding site [ion binding]; metal-binding site
926570001360	substrate binding pocket [chemical binding]; other site
926570001361	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
926570001362	homotrimer interaction site [polypeptide binding]; other site
926570001363	putative active site [active]
926570001364	TSCPD domain; Region: TSCPD; pfam12637
926570001365	NADH dehydrogenase; Validated; Region: PRK08183
926570001366	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
926570001367	mce related protein; Region: MCE; pfam02470
926570001368	Uncharacterized protein conserved in bacteria (DUF2155); Region: DUF2155; cl01970
926570001369	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
926570001370	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
926570001371	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570001372	ligand binding site [chemical binding]; other site
926570001373	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
926570001374	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
926570001375	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570001376	ligand binding site [chemical binding]; other site
926570001377	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
926570001378	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
926570001379	EthD domain; Region: EthD; cl17553
926570001380	pyruvate kinase; Provisional; Region: PRK06247
926570001381	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
926570001382	domain interfaces; other site
926570001383	active site
926570001384	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3492
926570001385	Uncharacterized protein conserved in bacteria (DUF2312); Region: DUF2312; pfam10073
926570001386	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
926570001387	dimer interface [polypeptide binding]; other site
926570001388	allosteric magnesium binding site [ion binding]; other site
926570001389	active site
926570001390	aspartate-rich active site metal binding site; other site
926570001391	Schiff base residues; other site
926570001392	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
926570001393	tartrate dehydrogenase; Region: TTC; TIGR02089
926570001394	Predicted membrane protein [Function unknown]; Region: COG3174
926570001395	Domain of unknown function (DUF4010); Region: DUF4010; pfam13194
926570001396	CHAD domain; Region: CHAD; pfam05235
926570001397	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
926570001398	ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Region: NrdJ_Z; TIGR02504
926570001399	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
926570001400	active site
926570001401	dimer interface [polypeptide binding]; other site
926570001402	effector binding site; other site
926570001403	TSCPD domain; Region: TSCPD; pfam12637
926570001404	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926570001405	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926570001406	DNA binding site [nucleotide binding]
926570001407	domain linker motif; other site
926570001408	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_4; cd06280
926570001409	putative dimerization interface [polypeptide binding]; other site
926570001410	putative ligand binding site [chemical binding]; other site
926570001411	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
926570001412	active site
926570001413	phosphorylation site [posttranslational modification]
926570001414	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
926570001415	dimerization domain swap beta strand [polypeptide binding]; other site
926570001416	regulatory protein interface [polypeptide binding]; other site
926570001417	active site
926570001418	regulatory phosphorylation site [posttranslational modification]; other site
926570001419	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
926570001420	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
926570001421	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926570001422	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926570001423	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
926570001424	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
926570001425	putative substrate binding site [chemical binding]; other site
926570001426	putative ATP binding site [chemical binding]; other site
926570001427	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
926570001428	active site
926570001429	P-loop; other site
926570001430	phosphorylation site [posttranslational modification]
926570001431	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
926570001432	active site
926570001433	P-loop; other site
926570001434	phosphorylation site [posttranslational modification]
926570001435	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
926570001436	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
926570001437	CoenzymeA binding site [chemical binding]; other site
926570001438	subunit interaction site [polypeptide binding]; other site
926570001439	PHB binding site; other site
926570001440	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
926570001441	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
926570001442	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
926570001443	transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282
926570001444	Uncharacterized conserved protein [Function unknown]; Region: COG0398
926570001445	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
926570001446	mercuric reductase; Validated; Region: PRK06370
926570001447	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570001448	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570001449	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926570001450	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926570001451	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
926570001452	active site
926570001453	metal binding site [ion binding]; metal-binding site
926570001454	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570001455	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
926570001456	FeS/SAM binding site; other site
926570001457	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570001458	benzoate transport; Region: 2A0115; TIGR00895
926570001459	putative substrate translocation pore; other site
926570001460	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
926570001461	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
926570001462	inhibitor site; inhibition site
926570001463	active site
926570001464	dimer interface [polypeptide binding]; other site
926570001465	catalytic residue [active]
926570001466	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
926570001467	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
926570001468	dimer interface [polypeptide binding]; other site
926570001469	NADP binding site [chemical binding]; other site
926570001470	catalytic residues [active]
926570001471	hypothetical protein; Validated; Region: PRK08245
926570001472	Peptidase family M48; Region: Peptidase_M48; cl12018
926570001473	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
926570001474	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
926570001475	putative dimer interface [polypeptide binding]; other site
926570001476	Predicted glycosyl transferase [General function prediction only]; Region: COG4671
926570001477	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
926570001478	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
926570001479	putative ADP-binding pocket [chemical binding]; other site
926570001480	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570001481	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926570001482	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926570001483	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926570001484	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570001485	Walker A/P-loop; other site
926570001486	ATP binding site [chemical binding]; other site
926570001487	Q-loop/lid; other site
926570001488	ABC transporter signature motif; other site
926570001489	Walker B; other site
926570001490	D-loop; other site
926570001491	H-loop/switch region; other site
926570001492	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926570001493	catalytic core [active]
926570001494	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
926570001495	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
926570001496	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
926570001497	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570001498	NAD(P) binding site [chemical binding]; other site
926570001499	active site
926570001500	aconitate hydratase; Validated; Region: PRK09277
926570001501	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
926570001502	substrate binding site [chemical binding]; other site
926570001503	ligand binding site [chemical binding]; other site
926570001504	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
926570001505	substrate binding site [chemical binding]; other site
926570001506	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13539
926570001507	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570001508	Walker A/P-loop; other site
926570001509	ATP binding site [chemical binding]; other site
926570001510	Q-loop/lid; other site
926570001511	ABC transporter signature motif; other site
926570001512	Walker B; other site
926570001513	D-loop; other site
926570001514	H-loop/switch region; other site
926570001515	heme exporter protein CcmB; Region: ccmB; TIGR01190
926570001516	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
926570001517	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
926570001518	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
926570001519	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
926570001520	active site
926570001521	Domain of unknown function (DUF1127); Region: DUF1127; pfam06568
926570001522	Methyltransferase domain; Region: Methyltransf_31; pfam13847
926570001523	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570001524	S-adenosylmethionine binding site [chemical binding]; other site
926570001525	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
926570001526	Part of AAA domain; Region: AAA_19; pfam13245
926570001527	Family description; Region: UvrD_C_2; pfam13538
926570001528	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
926570001529	FAD binding site [chemical binding]; other site
926570001530	VacJ like lipoprotein; Region: VacJ; cl01073
926570001531	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494
926570001532	ribosome maturation protein RimP; Reviewed; Region: PRK00092
926570001533	Sm and related proteins; Region: Sm_like; cl00259
926570001534	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
926570001535	putative oligomer interface [polypeptide binding]; other site
926570001536	putative RNA binding site [nucleotide binding]; other site
926570001537	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
926570001538	NusA N-terminal domain; Region: NusA_N; pfam08529
926570001539	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
926570001540	RNA binding site [nucleotide binding]; other site
926570001541	homodimer interface [polypeptide binding]; other site
926570001542	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
926570001543	G-X-X-G motif; other site
926570001544	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
926570001545	G-X-X-G motif; other site
926570001546	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
926570001547	Protein of unknown function (DUF448); Region: DUF448; pfam04296
926570001548	putative RNA binding cleft [nucleotide binding]; other site
926570001549	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
926570001550	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
926570001551	translation initiation factor IF-2; Region: IF-2; TIGR00487
926570001552	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
926570001553	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
926570001554	G1 box; other site
926570001555	putative GEF interaction site [polypeptide binding]; other site
926570001556	GTP/Mg2+ binding site [chemical binding]; other site
926570001557	Switch I region; other site
926570001558	G2 box; other site
926570001559	G3 box; other site
926570001560	Switch II region; other site
926570001561	G4 box; other site
926570001562	G5 box; other site
926570001563	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
926570001564	Translation-initiation factor 2; Region: IF-2; pfam11987
926570001565	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
926570001566	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
926570001567	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
926570001568	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
926570001569	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926570001570	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570001571	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570001572	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570001573	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
926570001574	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570001575	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570001576	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570001577	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
926570001578	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
926570001579	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
926570001580	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
926570001581	GTPase CgtA; Reviewed; Region: obgE; PRK12299
926570001582	GTP1/OBG; Region: GTP1_OBG; pfam01018
926570001583	Obg GTPase; Region: Obg; cd01898
926570001584	G1 box; other site
926570001585	GTP/Mg2+ binding site [chemical binding]; other site
926570001586	Switch I region; other site
926570001587	G2 box; other site
926570001588	G3 box; other site
926570001589	Switch II region; other site
926570001590	G4 box; other site
926570001591	G5 box; other site
926570001592	gamma-glutamyl kinase; Provisional; Region: PRK05429
926570001593	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
926570001594	nucleotide binding site [chemical binding]; other site
926570001595	homotetrameric interface [polypeptide binding]; other site
926570001596	putative phosphate binding site [ion binding]; other site
926570001597	putative allosteric binding site; other site
926570001598	PUA domain; Region: PUA; pfam01472
926570001599	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
926570001600	Mechanosensitive ion channel; Region: MS_channel; pfam00924
926570001601	arginyl-tRNA-protein transferase; Provisional; Region: PRK01305
926570001602	Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376
926570001603	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
926570001604	RDD family; Region: RDD; pfam06271
926570001605	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
926570001606	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
926570001607	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570001608	active site
926570001609	glutathionine S-transferase; Provisional; Region: PRK10542
926570001610	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
926570001611	C-terminal domain interface [polypeptide binding]; other site
926570001612	GSH binding site (G-site) [chemical binding]; other site
926570001613	dimer interface [polypeptide binding]; other site
926570001614	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
926570001615	N-terminal domain interface [polypeptide binding]; other site
926570001616	dimer interface [polypeptide binding]; other site
926570001617	substrate binding pocket (H-site) [chemical binding]; other site
926570001618	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926570001619	catalytic core [active]
926570001620	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
926570001621	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
926570001622	active site
926570001623	NAD binding site [chemical binding]; other site
926570001624	metal binding site [ion binding]; metal-binding site
926570001625	Amidase; Region: Amidase; cl11426
926570001626	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
926570001627	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926570001628	elongation factor G; Reviewed; Region: PRK12739
926570001629	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
926570001630	G1 box; other site
926570001631	putative GEF interaction site [polypeptide binding]; other site
926570001632	GTP/Mg2+ binding site [chemical binding]; other site
926570001633	Switch I region; other site
926570001634	G2 box; other site
926570001635	G3 box; other site
926570001636	Switch II region; other site
926570001637	G4 box; other site
926570001638	G5 box; other site
926570001639	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
926570001640	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
926570001641	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
926570001642	PAAR motif; Region: PAAR_motif; pfam05488
926570001643	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
926570001644	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
926570001645	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
926570001646	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
926570001647	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
926570001648	Catalytic site [active]
926570001649	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
926570001650	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
926570001651	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
926570001652	dimerization interface [polypeptide binding]; other site
926570001653	active site
926570001654	metal binding site [ion binding]; metal-binding site
926570001655	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
926570001656	dsRNA binding site [nucleotide binding]; other site
926570001657	GTPase Era; Reviewed; Region: era; PRK00089
926570001658	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
926570001659	G1 box; other site
926570001660	GTP/Mg2+ binding site [chemical binding]; other site
926570001661	Switch I region; other site
926570001662	G2 box; other site
926570001663	Switch II region; other site
926570001664	G3 box; other site
926570001665	G4 box; other site
926570001666	G5 box; other site
926570001667	KH domain; Region: KH_2; pfam07650
926570001668	G-X-X-G motif; other site
926570001669	pimeloyl-CoA dehydrogenase, small subunit; Region: pimD_small; TIGR03203
926570001670	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
926570001671	active site
926570001672	pimeloyl-CoA dehydrogenase, large subunit; Region: pimC_large; TIGR03204
926570001673	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570001674	active site
926570001675	dicarboxylate--CoA ligase PimA; Region: pimA; TIGR03205
926570001676	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570001677	acyl-activating enzyme (AAE) consensus motif; other site
926570001678	AMP binding site [chemical binding]; other site
926570001679	active site
926570001680	CoA binding site [chemical binding]; other site
926570001681	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570001682	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
926570001683	substrate binding site [chemical binding]; other site
926570001684	oxyanion hole (OAH) forming residues; other site
926570001685	trimer interface [polypeptide binding]; other site
926570001686	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
926570001687	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
926570001688	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926570001689	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
926570001690	Tetratricopeptide repeat; Region: TPR_16; pfam13432
926570001691	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570001692	TPR motif; other site
926570001693	binding surface
926570001694	TPR repeat; Region: TPR_11; pfam13414
926570001695	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570001696	binding surface
926570001697	TPR motif; other site
926570001698	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
926570001699	Uncharacterized family of ferritin-like proteins found in archaea and bacteria; Region: Ferritin_like_AB; cd01045
926570001700	diiron binding motif [ion binding]; other site
926570001701	Uncharacterized conserved protein [Function unknown]; Region: COG1633
926570001702	CCC1-related protein family; Region: CCC1_like_1; cd02437
926570001703	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
926570001704	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
926570001705	FMN binding site [chemical binding]; other site
926570001706	substrate binding site [chemical binding]; other site
926570001707	putative catalytic residue [active]
926570001708	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
926570001709	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
926570001710	putative C-terminal domain interface [polypeptide binding]; other site
926570001711	putative GSH binding site (G-site) [chemical binding]; other site
926570001712	putative dimer interface [polypeptide binding]; other site
926570001713	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
926570001714	putative N-terminal domain interface [polypeptide binding]; other site
926570001715	putative dimer interface [polypeptide binding]; other site
926570001716	putative substrate binding pocket (H-site) [chemical binding]; other site
926570001717	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
926570001718	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
926570001719	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
926570001720	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
926570001721	putative active site [active]
926570001722	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570001723	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570001724	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
926570001725	active site
926570001726	dimer interface [polypeptide binding]; other site
926570001727	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
926570001728	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
926570001729	Ligand Binding Site [chemical binding]; other site
926570001730	Molecular Tunnel; other site
926570001731	dihydroorotase; Validated; Region: PRK09060
926570001732	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570001733	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
926570001734	active site
926570001735	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
926570001736	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
926570001737	DNA binding residues [nucleotide binding]
926570001738	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
926570001739	IHF dimer interface [polypeptide binding]; other site
926570001740	IHF - DNA interface [nucleotide binding]; other site
926570001741	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
926570001742	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
926570001743	dimer interface [polypeptide binding]; other site
926570001744	active site
926570001745	CoA binding pocket [chemical binding]; other site
926570001746	putative phosphate acyltransferase; Provisional; Region: PRK05331
926570001747	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
926570001748	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
926570001749	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
926570001750	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
926570001751	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
926570001752	Predicted phosphatase [General function prediction only]; Region: PhoX; COG3211
926570001753	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
926570001754	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
926570001755	tetramerization interface [polypeptide binding]; other site
926570001756	NAD(P) binding site [chemical binding]; other site
926570001757	catalytic residues [active]
926570001758	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
926570001759	active site
926570001760	Int/Topo IB signature motif; other site
926570001761	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
926570001762	Helix-turn-helix domain; Region: HTH_17; pfam12728
926570001763	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
926570001764	active site
926570001765	catalytic residues [active]
926570001766	DNA binding site [nucleotide binding]
926570001767	Int/Topo IB signature motif; other site
926570001768	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
926570001769	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570001770	Coenzyme A binding pocket [chemical binding]; other site
926570001771	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570001772	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570001773	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; cl17722
926570001774	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
926570001775	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570001776	MULE transposase domain; Region: MULE; pfam10551
926570001777	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926570001778	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
926570001779	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926570001780	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926570001781	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570001782	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926570001783	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926570001784	inhibitor-cofactor binding pocket; inhibition site
926570001785	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570001786	catalytic residue [active]
926570001787	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570001788	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570001789	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570001790	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926570001791	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570001792	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570001793	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
926570001794	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
926570001795	putative trimer interface [polypeptide binding]; other site
926570001796	putative CoA binding site [chemical binding]; other site
926570001797	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
926570001798	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570001799	Protein of unknown function (DUF3095); Region: DUF3095; pfam11294
926570001800	MULE transposase domain; Region: MULE; pfam10551
926570001801	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
926570001802	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
926570001803	TolA protein; Region: tolA_full; TIGR02794
926570001804	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
926570001805	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
926570001806	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
926570001807	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
926570001808	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
926570001809	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570001810	Walker A/P-loop; other site
926570001811	ATP binding site [chemical binding]; other site
926570001812	Q-loop/lid; other site
926570001813	ABC transporter signature motif; other site
926570001814	Walker B; other site
926570001815	D-loop; other site
926570001816	H-loop/switch region; other site
926570001817	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
926570001818	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570001819	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926570001820	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926570001821	FtsX-like permease family; Region: FtsX; pfam02687
926570001822	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926570001823	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926570001824	Walker A/P-loop; other site
926570001825	ATP binding site [chemical binding]; other site
926570001826	Q-loop/lid; other site
926570001827	ABC transporter signature motif; other site
926570001828	Walker B; other site
926570001829	D-loop; other site
926570001830	H-loop/switch region; other site
926570001831	Uncharacterized ACR, COG1993; Region: DUF190; cl00872
926570001832	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
926570001833	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
926570001834	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
926570001835	transmembrane helices; other site
926570001836	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
926570001837	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926570001838	Walker A/P-loop; other site
926570001839	ATP binding site [chemical binding]; other site
926570001840	Q-loop/lid; other site
926570001841	ABC transporter signature motif; other site
926570001842	Walker B; other site
926570001843	D-loop; other site
926570001844	H-loop/switch region; other site
926570001845	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926570001846	FtsX-like permease family; Region: FtsX; pfam02687
926570001847	macrolide transporter subunit MacA; Provisional; Region: PRK11578
926570001848	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570001849	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
926570001850	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570001851	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570001852	active site
926570001853	phosphorylation site [posttranslational modification]
926570001854	intermolecular recognition site; other site
926570001855	dimerization interface [polypeptide binding]; other site
926570001856	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570001857	DNA binding site [nucleotide binding]
926570001858	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926570001859	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926570001860	dimerization interface [polypeptide binding]; other site
926570001861	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570001862	ATP binding site [chemical binding]; other site
926570001863	Mg2+ binding site [ion binding]; other site
926570001864	G-X-G motif; other site
926570001865	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570001866	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570001867	sequence-specific DNA binding site [nucleotide binding]; other site
926570001868	salt bridge; other site
926570001869	MarR family; Region: MarR_2; pfam12802
926570001870	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
926570001871	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
926570001872	Cl- selectivity filter; other site
926570001873	Cl- binding residues [ion binding]; other site
926570001874	pore gating glutamate residue; other site
926570001875	dimer interface [polypeptide binding]; other site
926570001876	FOG: CBS domain [General function prediction only]; Region: COG0517
926570001877	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc; cd04612
926570001878	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
926570001879	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570001880	catalytic residue [active]
926570001881	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926570001882	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
926570001883	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570001884	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570001885	TM-ABC transporter signature motif; other site
926570001886	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570001887	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570001888	Walker A/P-loop; other site
926570001889	ATP binding site [chemical binding]; other site
926570001890	Q-loop/lid; other site
926570001891	ABC transporter signature motif; other site
926570001892	Walker B; other site
926570001893	D-loop; other site
926570001894	H-loop/switch region; other site
926570001895	Cupin domain; Region: Cupin_2; pfam07883
926570001896	hypothetical protein; Provisional; Region: PRK07538
926570001897	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
926570001898	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
926570001899	pyrroloquinoline quinone biosynthesis protein PqqC; Provisional; Region: PRK05157
926570001900	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
926570001901	dimer interface [polypeptide binding]; other site
926570001902	ADP-ribose binding site [chemical binding]; other site
926570001903	active site
926570001904	nudix motif; other site
926570001905	metal binding site [ion binding]; metal-binding site
926570001906	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
926570001907	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
926570001908	HupF/HypC family; Region: HupF_HypC; pfam01455
926570001909	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
926570001910	Acylphosphatase; Region: Acylphosphatase; pfam00708
926570001911	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
926570001912	HypF finger; Region: zf-HYPF; pfam07503
926570001913	HypF finger; Region: zf-HYPF; pfam07503
926570001914	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
926570001915	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
926570001916	dimerization interface [polypeptide binding]; other site
926570001917	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
926570001918	ATP binding site [chemical binding]; other site
926570001919	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926570001920	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
926570001921	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
926570001922	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
926570001923	Rubredoxin; Region: Rubredoxin; pfam00301
926570001924	iron binding site [ion binding]; other site
926570001925	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
926570001926	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
926570001927	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
926570001928	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
926570001929	putative substrate-binding site; other site
926570001930	nickel binding site [ion binding]; other site
926570001931	Ni/Fe-hydrogenase, b-type cytochrome subunit; Region: CytB-hydogenase; TIGR02125
926570001932	hydrogenase 1 large subunit; Provisional; Region: PRK10170
926570001933	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
926570001934	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
926570001935	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
926570001936	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
926570001937	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
926570001938	putative coenzyme Q binding site [chemical binding]; other site
926570001939	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
926570001940	UbiA prenyltransferase family; Region: UbiA; pfam01040
926570001941	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926570001942	active site residue [active]
926570001943	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
926570001944	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
926570001945	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
926570001946	thiosulfate reductase PhsA; Provisional; Region: PRK15488
926570001947	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
926570001948	putative [Fe4-S4] binding site [ion binding]; other site
926570001949	putative molybdopterin cofactor binding site [chemical binding]; other site
926570001950	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
926570001951	putative molybdopterin cofactor binding site; other site
926570001952	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
926570001953	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
926570001954	active site residue [active]
926570001955	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
926570001956	active site residue [active]
926570001957	High-affinity nickel-transport protein; Region: NicO; cl00964
926570001958	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
926570001959	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
926570001960	dimerization interface [polypeptide binding]; other site
926570001961	domain crossover interface; other site
926570001962	redox-dependent activation switch; other site
926570001963	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
926570001964	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
926570001965	putative ribose interaction site [chemical binding]; other site
926570001966	putative ADP binding site [chemical binding]; other site
926570001967	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
926570001968	active site
926570001969	nucleotide binding site [chemical binding]; other site
926570001970	HIGH motif; other site
926570001971	KMSKS motif; other site
926570001972	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
926570001973	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570001974	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926570001975	Walker A/P-loop; other site
926570001976	ATP binding site [chemical binding]; other site
926570001977	Q-loop/lid; other site
926570001978	ABC transporter signature motif; other site
926570001979	Walker B; other site
926570001980	D-loop; other site
926570001981	H-loop/switch region; other site
926570001982	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570001983	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926570001984	Walker A/P-loop; other site
926570001985	ATP binding site [chemical binding]; other site
926570001986	Q-loop/lid; other site
926570001987	ABC transporter signature motif; other site
926570001988	Walker B; other site
926570001989	D-loop; other site
926570001990	H-loop/switch region; other site
926570001991	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926570001992	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926570001993	TM-ABC transporter signature motif; other site
926570001994	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926570001995	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570001996	TM-ABC transporter signature motif; other site
926570001997	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926570001998	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
926570001999	dimerization interface [polypeptide binding]; other site
926570002000	ligand binding site [chemical binding]; other site
926570002001	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
926570002002	potential frameshift: common BLAST hit: gi|148244045|ref|YP_001220283.1| RecD/TraA family helicase
926570002003	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
926570002004	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570002005	Walker A motif; other site
926570002006	ATP binding site [chemical binding]; other site
926570002007	Walker B motif; other site
926570002008	AAA domain; Region: AAA_23; pfam13476
926570002009	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
926570002010	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
926570002011	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
926570002012	pAE1 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal domain. This CD includes various bacterial integrases, including the predicted integrase of the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus...; Region: INT_pAE1; cd01188
926570002013	Int/Topo IB signature motif; other site
926570002014	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
926570002015	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570002016	active site
926570002017	DNA binding site [nucleotide binding]
926570002018	Int/Topo IB signature motif; other site
926570002019	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
926570002020	INT_SG5, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 5, N- and C-terminal domains. The CD contains mainly predicted bacterial integrase/recombinases; Region: INT_SG5; cd01190
926570002021	Int/Topo IB signature motif; other site
926570002022	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
926570002023	ParB-like nuclease domain; Region: ParBc; pfam02195
926570002024	PIN domain of the hypothetical protein MT3492 of Mycobacterium tuberculosis CDC1551 and other uncharacterized, annotated PilT protein domain proteins; Region: PIN_MT3492; cd09874
926570002025	putative active site [active]
926570002026	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
926570002027	P-loop containing NTP hydrolase pore-1; Region: AAA_34; pfam13872
926570002028	Helicase_C-like; Region: Helicase_C_4; pfam13871
926570002029	Toprim domain; Region: Toprim_3; pfam13362
926570002030	Protein of unknown function (DUF2493); Region: DUF2493; pfam10686
926570002031	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570002032	FeS/SAM binding site; other site
926570002033	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
926570002034	Protein of unknown function (DUF736); Region: DUF736; pfam05284
926570002035	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570002036	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570002037	non-specific DNA binding site [nucleotide binding]; other site
926570002038	salt bridge; other site
926570002039	sequence-specific DNA binding site [nucleotide binding]; other site
926570002040	Helix-turn-helix domain; Region: HTH_17; pfam12728
926570002041	Replication initiator protein A; Region: RPA; cl17860
926570002042	Protein of unknown function (DUF2840); Region: DUF2840; pfam11000
926570002043	Signal peptidase, peptidase S26; Region: Peptidase_S26; pfam10502
926570002044	conjugal transfer pilin processing protease TraF; Provisional; Region: PRK13838
926570002045	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
926570002046	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570002047	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570002048	catalytic residue [active]
926570002049	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
926570002050	Protein of unknown function (DUF3363); Region: DUF3363; pfam11843
926570002051	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
926570002052	ATP binding site [chemical binding]; other site
926570002053	Mg2+ binding site [ion binding]; other site
926570002054	G-X-G motif; other site
926570002055	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
926570002056	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
926570002057	putative active site [active]
926570002058	conjugal transfer coupling protein TraG; Provisional; Region: PRK13876
926570002059	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
926570002060	Walker A motif; other site
926570002061	ATP binding site [chemical binding]; other site
926570002062	Walker B motif; other site
926570002063	P-type conjugative transfer ATPase TrbB; Region: TrbB_P; TIGR02782
926570002064	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
926570002065	ATP binding site [chemical binding]; other site
926570002066	Walker A motif; other site
926570002067	hexamer interface [polypeptide binding]; other site
926570002068	Walker B motif; other site
926570002069	TrbC/VIRB2 family; Region: TrbC; pfam04956
926570002070	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
926570002071	conjugal transfer ATPase TrbE; Provisional; Region: PRK13873
926570002072	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
926570002073	Domain of unknown function DUF87; Region: DUF87; pfam01935
926570002074	conjugal transfer protein TrbJ; Provisional; Region: PRK13874
926570002075	conjugative transfer region protein TrbK; Region: other_trbK; TIGR04360
926570002076	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
926570002077	conjugal transfer protein TrbF; Provisional; Region: PRK13872
926570002078	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
926570002079	VirB7 interaction site; other site
926570002080	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
926570002081	Protein of unknown function (DUF2274); Region: DUF2274; cl02406
926570002082	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
926570002083	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
926570002084	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
926570002085	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
926570002086	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
926570002087	TIGR02687 family protein; Region: TIGR02687
926570002088	PglZ domain; Region: PglZ; pfam08665
926570002089	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
926570002090	synthetase active site [active]
926570002091	NTP binding site [chemical binding]; other site
926570002092	metal binding site [ion binding]; metal-binding site
926570002093	Methyltransferase domain; Region: Methyltransf_26; pfam13659
926570002094	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
926570002095	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
926570002096	Helix-turn-helix domain; Region: HTH_17; pfam12728
926570002097	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570002098	active site
926570002099	DNA binding site [nucleotide binding]
926570002100	Int/Topo IB signature motif; other site
926570002101	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
926570002102	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
926570002103	putative tRNA-binding site [nucleotide binding]; other site
926570002104	B3/4 domain; Region: B3_4; pfam03483
926570002105	tRNA synthetase B5 domain; Region: B5; smart00874
926570002106	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
926570002107	dimer interface [polypeptide binding]; other site
926570002108	motif 1; other site
926570002109	motif 3; other site
926570002110	motif 2; other site
926570002111	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
926570002112	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
926570002113	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
926570002114	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
926570002115	dimer interface [polypeptide binding]; other site
926570002116	motif 1; other site
926570002117	active site
926570002118	motif 2; other site
926570002119	motif 3; other site
926570002120	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
926570002121	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570002122	ligand binding site [chemical binding]; other site
926570002123	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
926570002124	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
926570002125	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
926570002126	Ligand Binding Site [chemical binding]; other site
926570002127	FtsH Extracellular; Region: FtsH_ext; pfam06480
926570002128	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
926570002129	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570002130	Walker A motif; other site
926570002131	ATP binding site [chemical binding]; other site
926570002132	Walker B motif; other site
926570002133	arginine finger; other site
926570002134	Peptidase family M41; Region: Peptidase_M41; pfam01434
926570002135	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
926570002136	enoyl-CoA hydratase; Provisional; Region: PRK06190
926570002137	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570002138	substrate binding site [chemical binding]; other site
926570002139	oxyanion hole (OAH) forming residues; other site
926570002140	trimer interface [polypeptide binding]; other site
926570002141	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
926570002142	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
926570002143	RNase E interface [polypeptide binding]; other site
926570002144	trimer interface [polypeptide binding]; other site
926570002145	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
926570002146	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
926570002147	RNase E interface [polypeptide binding]; other site
926570002148	trimer interface [polypeptide binding]; other site
926570002149	active site
926570002150	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
926570002151	putative nucleic acid binding region [nucleotide binding]; other site
926570002152	G-X-X-G motif; other site
926570002153	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
926570002154	RNA binding site [nucleotide binding]; other site
926570002155	domain interface; other site
926570002156	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
926570002157	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
926570002158	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
926570002159	Predicted membrane protein [Function unknown]; Region: COG2259
926570002160	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
926570002161	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
926570002162	active site
926570002163	catalytic residues [active]
926570002164	metal binding site [ion binding]; metal-binding site
926570002165	rpsU-divergently transcribed protein; Region: diverge_rpsU; TIGR02396
926570002166	COQ9; Region: COQ9; pfam08511
926570002167	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
926570002168	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
926570002169	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
926570002170	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
926570002171	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
926570002172	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
926570002173	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
926570002174	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
926570002175	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
926570002176	putative active site; other site
926570002177	catalytic residue [active]
926570002178	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
926570002179	thiamine phosphate binding site [chemical binding]; other site
926570002180	active site
926570002181	pyrophosphate binding site [ion binding]; other site
926570002182	active site
926570002183	Glycosyl transferase family 2; Region: Glyco_tranf_2_4; pfam13704
926570002184	Protein of unknown function (DUF563); Region: DUF563; pfam04577
926570002185	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926570002186	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570002187	active site
926570002188	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570002189	active site
926570002190	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
926570002191	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
926570002192	active site
926570002193	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
926570002194	active site
926570002195	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
926570002196	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
926570002197	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
926570002198	DDE superfamily endonuclease; Region: DDE_5; cl17874
926570002199	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570002200	Winged helix-turn helix; Region: HTH_29; pfam13551
926570002201	Integrase core domain; Region: rve; pfam00665
926570002202	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570002203	transposase/IS protein; Provisional; Region: PRK09183
926570002204	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570002205	Walker A motif; other site
926570002206	ATP binding site [chemical binding]; other site
926570002207	Walker B motif; other site
926570002208	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570002209	MULE transposase domain; Region: MULE; pfam10551
926570002210	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570002211	MULE transposase domain; Region: MULE; pfam10551
926570002212	voltage-gated potassium channel; Provisional; Region: PRK10537
926570002213	Ion channel; Region: Ion_trans_2; pfam07885
926570002214	TrkA-N domain; Region: TrkA_N; pfam02254
926570002215	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
926570002216	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
926570002217	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
926570002218	ATP binding site [chemical binding]; other site
926570002219	active site
926570002220	substrate binding site [chemical binding]; other site
926570002221	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
926570002222	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
926570002223	F0F1 ATP synthase subunit B'; Validated; Region: PRK07353
926570002224	ATP synthase subunit C; Region: ATP-synt_C; cl00466
926570002225	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
926570002226	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
926570002227	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
926570002228	AAA domain; Region: AAA_23; pfam13476
926570002229	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
926570002230	Walker A/P-loop; other site
926570002231	ATP binding site [chemical binding]; other site
926570002232	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
926570002233	ABC transporter signature motif; other site
926570002234	Walker B; other site
926570002235	D-loop; other site
926570002236	H-loop/switch region; other site
926570002237	Thioredoxin; Region: Thioredoxin_4; pfam13462
926570002238	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
926570002239	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570002240	active site
926570002241	DNA repair protein RadA; Provisional; Region: PRK11823
926570002242	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
926570002243	Walker A motif; other site
926570002244	ATP binding site [chemical binding]; other site
926570002245	Walker B motif; other site
926570002246	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
926570002247	Colicin V production protein; Region: Colicin_V; pfam02674
926570002248	amidophosphoribosyltransferase; Provisional; Region: PRK09123
926570002249	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
926570002250	active site
926570002251	tetramer interface [polypeptide binding]; other site
926570002252	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570002253	active site
926570002254	methionine sulfoxide reductase A; Provisional; Region: PRK00058
926570002255	Protein of unknown function (DUF1150); Region: DUF1150; pfam06620
926570002256	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
926570002257	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
926570002258	putative dimer interface [polypeptide binding]; other site
926570002259	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
926570002260	active site
926570002261	catalytic residues [active]
926570002262	metal binding site [ion binding]; metal-binding site
926570002263	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
926570002264	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
926570002265	putative active site [active]
926570002266	substrate binding site [chemical binding]; other site
926570002267	putative cosubstrate binding site; other site
926570002268	catalytic site [active]
926570002269	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
926570002270	substrate binding site [chemical binding]; other site
926570002271	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
926570002272	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
926570002273	dimerization interface 3.5A [polypeptide binding]; other site
926570002274	active site
926570002275	translation initiation factor IF-3; Region: infC; TIGR00168
926570002276	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
926570002277	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
926570002278	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
926570002279	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
926570002280	putative catalytic site [active]
926570002281	putative phosphate binding site [ion binding]; other site
926570002282	active site
926570002283	metal binding site A [ion binding]; metal-binding site
926570002284	DNA binding site [nucleotide binding]
926570002285	putative AP binding site [nucleotide binding]; other site
926570002286	putative metal binding site B [ion binding]; other site
926570002287	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
926570002288	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
926570002289	Peptidase C26; Region: Peptidase_C26; pfam07722
926570002290	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
926570002291	catalytic triad [active]
926570002292	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
926570002293	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
926570002294	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926570002295	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
926570002296	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
926570002297	interface (dimer of trimers) [polypeptide binding]; other site
926570002298	Substrate-binding/catalytic site; other site
926570002299	Zn-binding sites [ion binding]; other site
926570002300	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
926570002301	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
926570002302	GIY-YIG motif/motif A; other site
926570002303	active site
926570002304	catalytic site [active]
926570002305	putative DNA binding site [nucleotide binding]; other site
926570002306	metal binding site [ion binding]; metal-binding site
926570002307	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
926570002308	tail sheath protein; Provisional; Region: 18; PHA02539
926570002309	Hint domain; Region: Hint_2; pfam13403
926570002310	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
926570002311	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
926570002312	Putative S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_28; pfam02636
926570002313	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
926570002314	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570002315	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
926570002316	NAD(P) binding site [chemical binding]; other site
926570002317	active site
926570002318	Membrane fusogenic activity; Region: BMFP; pfam04380
926570002319	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
926570002320	active site
926570002321	dimer interface [polypeptide binding]; other site
926570002322	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
926570002323	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
926570002324	putative NAD(P) binding site [chemical binding]; other site
926570002325	dimer interface [polypeptide binding]; other site
926570002326	Protein of unknown function DUF45; Region: DUF45; pfam01863
926570002327	hypothetical protein; Provisional; Region: PRK05170
926570002328	The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524
926570002329	putative amphipathic alpha helix; other site
926570002330	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926570002331	catalytic core [active]
926570002332	ABC-2 type transporter; Region: ABC2_membrane; cl17235
926570002333	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
926570002334	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
926570002335	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926570002336	Walker A/P-loop; other site
926570002337	ATP binding site [chemical binding]; other site
926570002338	Q-loop/lid; other site
926570002339	ABC transporter signature motif; other site
926570002340	Walker B; other site
926570002341	D-loop; other site
926570002342	H-loop/switch region; other site
926570002343	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570002344	S-adenosylmethionine binding site [chemical binding]; other site
926570002345	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
926570002346	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
926570002347	hypothetical protein; Provisional; Region: PRK06034
926570002348	Chorismate mutase type II; Region: CM_2; cl00693
926570002349	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
926570002350	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570002351	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570002352	homodimer interface [polypeptide binding]; other site
926570002353	catalytic residue [active]
926570002354	cyclohexadienyl dehydrogenase; Validated; Region: PRK07502
926570002355	prephenate dehydrogenase; Validated; Region: PRK08507
926570002356	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05389
926570002357	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
926570002358	RNA binding site [nucleotide binding]; other site
926570002359	active site
926570002360	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
926570002361	16S/18S rRNA binding site [nucleotide binding]; other site
926570002362	S13e-L30e interaction site [polypeptide binding]; other site
926570002363	25S rRNA binding site [nucleotide binding]; other site
926570002364	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
926570002365	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
926570002366	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
926570002367	dimerization domain swap beta strand [polypeptide binding]; other site
926570002368	regulatory protein interface [polypeptide binding]; other site
926570002369	active site
926570002370	regulatory phosphorylation site [posttranslational modification]; other site
926570002371	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
926570002372	active pocket/dimerization site; other site
926570002373	active site
926570002374	phosphorylation site [posttranslational modification]
926570002375	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
926570002376	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
926570002377	metal-binding site [ion binding]
926570002378	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570002379	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570002380	active site
926570002381	phosphorylation site [posttranslational modification]
926570002382	intermolecular recognition site; other site
926570002383	dimerization interface [polypeptide binding]; other site
926570002384	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570002385	DNA binding site [nucleotide binding]
926570002386	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
926570002387	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926570002388	dimerization interface [polypeptide binding]; other site
926570002389	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570002390	ATP binding site [chemical binding]; other site
926570002391	Mg2+ binding site [ion binding]; other site
926570002392	G-X-G motif; other site
926570002393	benzoate transport; Region: 2A0115; TIGR00895
926570002394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570002395	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570002396	Peptidase S8 family domain in Autotransporter serine proteases; Region: Peptidases_S8_Autotransporter_serine_protease_like; cd04848
926570002397	catalytic triad [active]
926570002398	putative active site [active]
926570002399	Autotransporter beta-domain; Region: Autotransporter; smart00869
926570002400	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
926570002401	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
926570002402	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
926570002403	N- and C-terminal domain interface [polypeptide binding]; other site
926570002404	active site
926570002405	MgATP binding site [chemical binding]; other site
926570002406	catalytic site [active]
926570002407	metal binding site [ion binding]; metal-binding site
926570002408	carbohydrate binding site [chemical binding]; other site
926570002409	putative homodimer interface [polypeptide binding]; other site
926570002410	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926570002411	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926570002412	substrate binding site [chemical binding]; other site
926570002413	ATP binding site [chemical binding]; other site
926570002414	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926570002415	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
926570002416	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926570002417	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926570002418	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926570002419	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570002420	dimer interface [polypeptide binding]; other site
926570002421	conserved gate region; other site
926570002422	putative PBP binding loops; other site
926570002423	ABC-ATPase subunit interface; other site
926570002424	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926570002425	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570002426	dimer interface [polypeptide binding]; other site
926570002427	conserved gate region; other site
926570002428	putative PBP binding loops; other site
926570002429	ABC-ATPase subunit interface; other site
926570002430	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
926570002431	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
926570002432	Walker A/P-loop; other site
926570002433	ATP binding site [chemical binding]; other site
926570002434	Q-loop/lid; other site
926570002435	ABC transporter signature motif; other site
926570002436	Walker B; other site
926570002437	D-loop; other site
926570002438	H-loop/switch region; other site
926570002439	TOBE domain; Region: TOBE_2; pfam08402
926570002440	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570002441	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926570002442	NAD(P) binding site [chemical binding]; other site
926570002443	active site
926570002444	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570002445	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
926570002446	NAD(P) binding site [chemical binding]; other site
926570002447	active site
926570002448	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
926570002449	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
926570002450	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
926570002451	phosphogluconate dehydratase; Validated; Region: PRK09054
926570002452	6-phosphogluconate dehydratase; Region: edd; TIGR01196
926570002453	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
926570002454	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
926570002455	active site
926570002456	intersubunit interface [polypeptide binding]; other site
926570002457	catalytic residue [active]
926570002458	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
926570002459	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570002460	putative substrate translocation pore; other site
926570002461	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570002462	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
926570002463	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
926570002464	transmembrane helices; other site
926570002465	Carbon monoxide dehydrogenase subunit G (CoxG); Region: CoxG; cd05018
926570002466	putative hydrophobic ligand binding site [chemical binding]; other site
926570002467	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
926570002468	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570002469	Walker A motif; other site
926570002470	ATP binding site [chemical binding]; other site
926570002471	Walker B motif; other site
926570002472	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570002473	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570002474	metal binding site [ion binding]; metal-binding site
926570002475	active site
926570002476	I-site; other site
926570002477	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570002478	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
926570002479	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
926570002480	conserved cys residue [active]
926570002481	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
926570002482	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
926570002483	conserved cys residue [active]
926570002484	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570002485	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570002486	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
926570002487	classical (c) SDRs; Region: SDR_c; cd05233
926570002488	NAD(P) binding site [chemical binding]; other site
926570002489	active site
926570002490	acetoacetate decarboxylase; Provisional; Region: PRK02265
926570002491	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
926570002492	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
926570002493	nucleophile elbow; other site
926570002494	Patatin phospholipase; Region: DUF3734; pfam12536
926570002495	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
926570002496	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
926570002497	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
926570002498	putative inner membrane protein; Provisional; Region: PRK11099
926570002499	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
926570002500	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
926570002501	active site residue [active]
926570002502	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
926570002503	active site residue [active]
926570002504	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926570002505	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926570002506	DNA binding site [nucleotide binding]
926570002507	domain linker motif; other site
926570002508	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926570002509	dimerization interface [polypeptide binding]; other site
926570002510	ligand binding site [chemical binding]; other site
926570002511	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
926570002512	D-xylulose kinase; Region: XylB; TIGR01312
926570002513	N- and C-terminal domain interface [polypeptide binding]; other site
926570002514	active site
926570002515	MgATP binding site [chemical binding]; other site
926570002516	catalytic site [active]
926570002517	metal binding site [ion binding]; metal-binding site
926570002518	xylulose binding site [chemical binding]; other site
926570002519	homodimer interface [polypeptide binding]; other site
926570002520	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
926570002521	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926570002522	ligand binding site [chemical binding]; other site
926570002523	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570002524	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570002525	Walker A/P-loop; other site
926570002526	ATP binding site [chemical binding]; other site
926570002527	Q-loop/lid; other site
926570002528	ABC transporter signature motif; other site
926570002529	Walker B; other site
926570002530	D-loop; other site
926570002531	H-loop/switch region; other site
926570002532	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570002533	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570002534	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570002535	TM-ABC transporter signature motif; other site
926570002536	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
926570002537	IHF dimer interface [polypeptide binding]; other site
926570002538	IHF - DNA interface [nucleotide binding]; other site
926570002539	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570002540	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926570002541	NAD(P) binding site [chemical binding]; other site
926570002542	active site
926570002543	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
926570002544	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
926570002545	NADP-binding site; other site
926570002546	homotetramer interface [polypeptide binding]; other site
926570002547	substrate binding site [chemical binding]; other site
926570002548	homodimer interface [polypeptide binding]; other site
926570002549	active site
926570002550	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570002551	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570002552	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570002553	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
926570002554	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
926570002555	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926570002556	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926570002557	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926570002558	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
926570002559	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570002560	motif II; other site
926570002561	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926570002562	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
926570002563	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
926570002564	Protein of unknown function, DUF488; Region: DUF488; pfam04343
926570002565	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
926570002566	sulfotransferase; Region: PLN02164
926570002567	Protein of Unknown function (DUF2784); Region: DUF2784; pfam10861
926570002568	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
926570002569	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
926570002570	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
926570002571	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
926570002572	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570002573	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570002574	dimer interface [polypeptide binding]; other site
926570002575	putative CheW interface [polypeptide binding]; other site
926570002576	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926570002577	GAF domain; Region: GAF; pfam01590
926570002578	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926570002579	GAF domain; Region: GAF; pfam01590
926570002580	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570002581	PAS fold; Region: PAS_3; pfam08447
926570002582	putative active site [active]
926570002583	heme pocket [chemical binding]; other site
926570002584	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570002585	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570002586	metal binding site [ion binding]; metal-binding site
926570002587	active site
926570002588	I-site; other site
926570002589	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570002590	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
926570002591	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
926570002592	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
926570002593	Family-5 Uracil-DNA glycosylases (UDG), found in thermophilic organisms; Region: UDG_F5_TTUDGB_like; cd10031
926570002594	Fe-S cluster binding site [ion binding]; other site
926570002595	DNA binding site [nucleotide binding]
926570002596	active site
926570002597	Uncharacterized conserved protein [Function unknown]; Region: COG1432
926570002598	LabA_like proteins; Region: LabA; cd10911
926570002599	putative metal binding site [ion binding]; other site
926570002600	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
926570002601	catalytic center binding site [active]
926570002602	ATP binding site [chemical binding]; other site
926570002603	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
926570002604	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
926570002605	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926570002606	Zn2+ binding site [ion binding]; other site
926570002607	Mg2+ binding site [ion binding]; other site
926570002608	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
926570002609	synthetase active site [active]
926570002610	NTP binding site [chemical binding]; other site
926570002611	metal binding site [ion binding]; metal-binding site
926570002612	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
926570002613	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
926570002614	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
926570002615	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
926570002616	2-isopropylmalate synthase; Validated; Region: PRK00915
926570002617	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
926570002618	active site
926570002619	catalytic residues [active]
926570002620	metal binding site [ion binding]; metal-binding site
926570002621	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
926570002622	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926570002623	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
926570002624	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926570002625	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
926570002626	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
926570002627	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
926570002628	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
926570002629	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926570002630	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570002631	dimer interface [polypeptide binding]; other site
926570002632	conserved gate region; other site
926570002633	putative PBP binding loops; other site
926570002634	ABC-ATPase subunit interface; other site
926570002635	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926570002636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570002637	dimer interface [polypeptide binding]; other site
926570002638	putative PBP binding loops; other site
926570002639	ABC-ATPase subunit interface; other site
926570002640	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
926570002641	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570002642	Walker A/P-loop; other site
926570002643	ATP binding site [chemical binding]; other site
926570002644	Q-loop/lid; other site
926570002645	ABC transporter signature motif; other site
926570002646	Walker B; other site
926570002647	D-loop; other site
926570002648	H-loop/switch region; other site
926570002649	TOBE domain; Region: TOBE_2; pfam08402
926570002650	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
926570002651	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
926570002652	hexamer interface [polypeptide binding]; other site
926570002653	ligand binding site [chemical binding]; other site
926570002654	putative active site [active]
926570002655	NAD(P) binding site [chemical binding]; other site
926570002656	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
926570002657	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570002658	non-specific DNA binding site [nucleotide binding]; other site
926570002659	salt bridge; other site
926570002660	sequence-specific DNA binding site [nucleotide binding]; other site
926570002661	Cupin domain; Region: Cupin_2; pfam07883
926570002662	putative aminotransferase; Validated; Region: PRK07480
926570002663	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926570002664	inhibitor-cofactor binding pocket; inhibition site
926570002665	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570002666	catalytic residue [active]
926570002667	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
926570002668	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
926570002669	Radical SAM superfamily; Region: Radical_SAM; pfam04055
926570002670	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570002671	FeS/SAM binding site; other site
926570002672	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
926570002673	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
926570002674	Substrate binding site; other site
926570002675	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
926570002676	Creatinine amidohydrolase; Region: Creatininase; cl00618
926570002677	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
926570002678	substrate binding site; other site
926570002679	dimer interface; other site
926570002680	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
926570002681	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
926570002682	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
926570002683	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926570002684	Walker A/P-loop; other site
926570002685	ATP binding site [chemical binding]; other site
926570002686	Q-loop/lid; other site
926570002687	ABC transporter signature motif; other site
926570002688	Walker B; other site
926570002689	D-loop; other site
926570002690	H-loop/switch region; other site
926570002691	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570002692	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
926570002693	Walker A/P-loop; other site
926570002694	ATP binding site [chemical binding]; other site
926570002695	Q-loop/lid; other site
926570002696	ABC transporter signature motif; other site
926570002697	Walker B; other site
926570002698	D-loop; other site
926570002699	H-loop/switch region; other site
926570002700	pantoate--beta-alanine ligase; Reviewed; Region: panC; PRK00380
926570002701	pantoate--beta-alanine ligase; Region: panC; TIGR00018
926570002702	active site
926570002703	nucleotide binding site [chemical binding]; other site
926570002704	HIGH motif; other site
926570002705	KMSKS motif; other site
926570002706	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570002707	Protein of unknown function (DUF3253); Region: DUF3253; pfam11625
926570002708	Protein of unknown function (DUF1499); Region: DUF1499; cl01841
926570002709	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
926570002710	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926570002711	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
926570002712	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
926570002713	Glycerophosphodiester phosphodiesterase domain of putative Silicibacter pomeroyi glycerophosphodiester phosphodiesterase and similar proteins; Region: GDPD_SpGDE_like; cd08567
926570002714	active site
926570002715	catalytic site [active]
926570002716	metal binding site [ion binding]; metal-binding site
926570002717	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
926570002718	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926570002719	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570002720	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
926570002721	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570002722	putative substrate translocation pore; other site
926570002723	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
926570002724	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
926570002725	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
926570002726	isocitrate dehydrogenase; Validated; Region: PRK08299
926570002727	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
926570002728	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570002729	active site
926570002730	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570002731	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570002732	metal binding site [ion binding]; metal-binding site
926570002733	active site
926570002734	I-site; other site
926570002735	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
926570002736	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
926570002737	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
926570002738	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
926570002739	NPCBM-associated, NEW3 domain of alpha-galactosidase; Region: NPCBM_assoc; pfam10633
926570002740	cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030
926570002741	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
926570002742	DXD motif; other site
926570002743	PilZ domain; Region: PilZ; pfam07238
926570002744	endo-1,4-D-glucanase; Provisional; Region: PRK11097
926570002745	Bacterial cellulose synthase subunit; Region: BcsB; pfam03170
926570002746	Ycf27; Reviewed; Region: orf27; CHL00148
926570002747	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
926570002748	active site
926570002749	phosphorylation site [posttranslational modification]
926570002750	dimerization interface [polypeptide binding]; other site
926570002751	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570002752	DNA binding site [nucleotide binding]
926570002753	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926570002754	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
926570002755	ligand binding site [chemical binding]; other site
926570002756	flexible hinge region; other site
926570002757	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
926570002758	putative switch regulator; other site
926570002759	non-specific DNA interactions [nucleotide binding]; other site
926570002760	DNA binding site [nucleotide binding]
926570002761	sequence specific DNA binding site [nucleotide binding]; other site
926570002762	putative cAMP binding site [chemical binding]; other site
926570002763	osmolarity response regulator; Provisional; Region: ompR; PRK09468
926570002764	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570002765	active site
926570002766	phosphorylation site [posttranslational modification]
926570002767	intermolecular recognition site; other site
926570002768	dimerization interface [polypeptide binding]; other site
926570002769	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570002770	DNA binding site [nucleotide binding]
926570002771	PAS domain; Region: PAS_9; pfam13426
926570002772	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570002773	putative active site [active]
926570002774	heme pocket [chemical binding]; other site
926570002775	PAS domain S-box; Region: sensory_box; TIGR00229
926570002776	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570002777	putative active site [active]
926570002778	heme pocket [chemical binding]; other site
926570002779	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570002780	dimer interface [polypeptide binding]; other site
926570002781	phosphorylation site [posttranslational modification]
926570002782	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570002783	ATP binding site [chemical binding]; other site
926570002784	G-X-G motif; other site
926570002785	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570002786	active site
926570002787	phosphorylation site [posttranslational modification]
926570002788	intermolecular recognition site; other site
926570002789	dimerization interface [polypeptide binding]; other site
926570002790	Bacterial PH domain; Region: DUF304; pfam03703
926570002791	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570002792	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570002793	non-specific DNA binding site [nucleotide binding]; other site
926570002794	salt bridge; other site
926570002795	sequence-specific DNA binding site [nucleotide binding]; other site
926570002796	Predicted transcriptional regulator [General function prediction only]; Region: COG3800
926570002797	Domain of unknown function (DUF955); Region: DUF955; pfam06114
926570002798	Predicted transcriptional regulator (DUF2083); Region: DUF2083; pfam09856
926570002799	recombination protein F; Reviewed; Region: recF; PRK00064
926570002800	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570002801	Walker A/P-loop; other site
926570002802	ATP binding site [chemical binding]; other site
926570002803	Q-loop/lid; other site
926570002804	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570002805	Walker B; other site
926570002806	D-loop; other site
926570002807	H-loop/switch region; other site
926570002808	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
926570002809	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
926570002810	active site
926570002811	Riboflavin kinase; Region: Flavokinase; smart00904
926570002812	(R)-hydratase [(R)-specific enoyl-CoA hydratase] catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. (R)-hydratase contains a hot-dog fold similar to those of thioesterase...; Region: R_hydratase; cd03449
926570002813	dimer interaction site [polypeptide binding]; other site
926570002814	substrate-binding tunnel; other site
926570002815	active site
926570002816	catalytic site [active]
926570002817	substrate binding site [chemical binding]; other site
926570002818	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926570002819	Ligand binding site; other site
926570002820	Putative Catalytic site; other site
926570002821	DXD motif; other site
926570002822	Uncharacterized protein conserved in bacteria (DUF2125); Region: DUF2125; pfam09898
926570002823	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570002824	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570002825	putative substrate translocation pore; other site
926570002826	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570002827	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926570002828	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926570002829	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570002830	Walker A/P-loop; other site
926570002831	ATP binding site [chemical binding]; other site
926570002832	Q-loop/lid; other site
926570002833	ABC transporter signature motif; other site
926570002834	Walker B; other site
926570002835	D-loop; other site
926570002836	H-loop/switch region; other site
926570002837	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570002838	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570002839	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
926570002840	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
926570002841	substrate binding site; other site
926570002842	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570002843	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
926570002844	NAD(P) binding site [chemical binding]; other site
926570002845	active site
926570002846	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
926570002847	Putative zinc binding domain; Region: Methyltransf_13; pfam08421
926570002848	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570002849	Methyltransferase domain; Region: Methyltransf_12; pfam08242
926570002850	C-methyltransferase C-terminal domain; Region: Methyltransf_14; pfam08484
926570002851	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
926570002852	extended (e) SDRs; Region: SDR_e; cd08946
926570002853	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
926570002854	NAD(P) binding site [chemical binding]; other site
926570002855	active site
926570002856	substrate binding site [chemical binding]; other site
926570002857	Cephalosporin hydroxylase; Region: CmcI; pfam04989
926570002858	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570002859	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570002860	dimer interface [polypeptide binding]; other site
926570002861	putative CheW interface [polypeptide binding]; other site
926570002862	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
926570002863	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
926570002864	Cu(I) binding site [ion binding]; other site
926570002865	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
926570002866	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
926570002867	Coenzyme Q (ubiquinone) biosynthesis protein Coq4; Region: Coq4; cl02093
926570002868	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
926570002869	NADH dehydrogenase; Region: NADHdh; cl00469
926570002870	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570002871	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
926570002872	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
926570002873	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
926570002874	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Region: NuoI; COG1143
926570002875	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
926570002876	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570002877	hydrogenase 4 subunit B; Validated; Region: PRK06521
926570002878	Uncharacterized ACR, COG1993; Region: DUF190; cl00872
926570002879	PII-like signaling protein [Signal transduction mechanisms]; Region: COG1993
926570002880	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
926570002881	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570002882	active site
926570002883	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
926570002884	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
926570002885	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
926570002886	substrate binding site; other site
926570002887	tetramer interface; other site
926570002888	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
926570002889	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
926570002890	NAD binding site [chemical binding]; other site
926570002891	substrate binding site [chemical binding]; other site
926570002892	homodimer interface [polypeptide binding]; other site
926570002893	active site
926570002894	Transposase; Region: HTH_Tnp_1; cl17663
926570002895	potential frameshift: common BLAST hit: gi|209548279|ref|YP_002280196.1| Integrase catalytic region
926570002896	Integrase core domain; Region: rve; pfam00665
926570002897	Integrase core domain; Region: rve_3; pfam13683
926570002898	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
926570002899	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
926570002900	metal binding site [ion binding]; metal-binding site
926570002901	putative dimer interface [polypeptide binding]; other site
926570002902	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
926570002903	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
926570002904	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
926570002905	CAP-like domain; other site
926570002906	active site
926570002907	primary dimer interface [polypeptide binding]; other site
926570002908	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
926570002909	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
926570002910	Protein of unknown function (DUF563); Region: DUF563; pfam04577
926570002911	multifunctional aminopeptidase A; Provisional; Region: PRK00913
926570002912	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
926570002913	interface (dimer of trimers) [polypeptide binding]; other site
926570002914	Substrate-binding/catalytic site; other site
926570002915	Zn-binding sites [ion binding]; other site
926570002916	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
926570002917	active site
926570002918	fructokinase; Reviewed; Region: PRK09557
926570002919	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926570002920	nucleotide binding site [chemical binding]; other site
926570002921	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
926570002922	CPxP  motif; other site
926570002923	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
926570002924	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_2; cd11599
926570002925	putative active site [active]
926570002926	Zn binding site [ion binding]; other site
926570002927	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
926570002928	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
926570002929	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
926570002930	substrate binding pocket [chemical binding]; other site
926570002931	chain length determination region; other site
926570002932	substrate-Mg2+ binding site; other site
926570002933	catalytic residues [active]
926570002934	aspartate-rich region 1; other site
926570002935	active site lid residues [active]
926570002936	aspartate-rich region 2; other site
926570002937	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926570002938	active site
926570002939	Glycosyl transferase family 2; Region: Glyco_tranf_2_4; pfam13704
926570002940	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
926570002941	Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles and Arabidopsis; Region: ttLC_FACS_AEE21_like; cd12118
926570002942	acyl-activating enzyme (AAE) consensus motif; other site
926570002943	putative active site [active]
926570002944	AMP binding site [chemical binding]; other site
926570002945	putative CoA binding site [chemical binding]; other site
926570002946	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570002947	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570002948	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570002949	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
926570002950	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
926570002951	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
926570002952	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
926570002953	active site
926570002954	ribosomal RNA small subunit methyltransferase RsmB; Region: rsmB; TIGR00563
926570002955	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570002956	S-adenosylmethionine binding site [chemical binding]; other site
926570002957	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570002958	Coenzyme A binding pocket [chemical binding]; other site
926570002959	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
926570002960	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570002961	active site
926570002962	DNA binding site [nucleotide binding]
926570002963	Int/Topo IB signature motif; other site
926570002964	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
926570002965	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
926570002966	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
926570002967	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926570002968	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926570002969	Walker A/P-loop; other site
926570002970	ATP binding site [chemical binding]; other site
926570002971	Q-loop/lid; other site
926570002972	ABC transporter signature motif; other site
926570002973	Walker B; other site
926570002974	D-loop; other site
926570002975	H-loop/switch region; other site
926570002976	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
926570002977	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
926570002978	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926570002979	Walker A/P-loop; other site
926570002980	ATP binding site [chemical binding]; other site
926570002981	Q-loop/lid; other site
926570002982	ABC transporter signature motif; other site
926570002983	Walker B; other site
926570002984	D-loop; other site
926570002985	H-loop/switch region; other site
926570002986	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926570002987	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926570002988	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570002989	dimer interface [polypeptide binding]; other site
926570002990	conserved gate region; other site
926570002991	putative PBP binding loops; other site
926570002992	ABC-ATPase subunit interface; other site
926570002993	The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513
926570002994	peptide binding site [polypeptide binding]; other site
926570002995	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926570002996	dimer interface [polypeptide binding]; other site
926570002997	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
926570002998	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
926570002999	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG2607
926570003000	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570003001	Walker A motif; other site
926570003002	ATP binding site [chemical binding]; other site
926570003003	Walker B motif; other site
926570003004	Preprotein translocase subunit; Region: YajC; pfam02699
926570003005	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
926570003006	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
926570003007	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
926570003008	Squalene/phytoene synthase; Region: SQS_PSY; pfam00494
926570003009	substrate binding pocket [chemical binding]; other site
926570003010	DNA gyrase subunit A; Validated; Region: PRK05560
926570003011	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
926570003012	CAP-like domain; other site
926570003013	active site
926570003014	primary dimer interface [polypeptide binding]; other site
926570003015	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926570003016	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926570003017	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926570003018	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926570003019	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
926570003020	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
926570003021	active site
926570003022	(T/H)XGH motif; other site
926570003023	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
926570003024	active site
926570003025	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570003026	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570003027	Hint domain; Region: Hint_2; pfam13403
926570003028	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570003029	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570003030	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_4; cd08463
926570003031	putative substrate binding pocket [chemical binding]; other site
926570003032	putative dimerization interface [polypeptide binding]; other site
926570003033	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
926570003034	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
926570003035	active site
926570003036	catalytic site [active]
926570003037	tetramer interface [polypeptide binding]; other site
926570003038	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
926570003039	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
926570003040	metal binding site [ion binding]; metal-binding site
926570003041	allantoate amidohydrolase; Reviewed; Region: PRK09290
926570003042	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
926570003043	active site
926570003044	metal binding site [ion binding]; metal-binding site
926570003045	dimer interface [polypeptide binding]; other site
926570003046	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
926570003047	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
926570003048	MOFRL family; Region: MOFRL; pfam05161
926570003049	tartronate semialdehyde reductase; Provisional; Region: PRK15059
926570003050	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926570003051	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
926570003052	glyoxylate carboligase; Provisional; Region: PRK11269
926570003053	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926570003054	PYR/PP interface [polypeptide binding]; other site
926570003055	dimer interface [polypeptide binding]; other site
926570003056	TPP binding site [chemical binding]; other site
926570003057	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926570003058	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926570003059	TPP-binding site [chemical binding]; other site
926570003060	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
926570003061	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570003062	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570003063	dimerization interface [polypeptide binding]; other site
926570003064	xanthine dehydrogenase, small subunit; Region: xanthine_xdhA; TIGR02963
926570003065	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926570003066	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
926570003067	xanthine dehydrogenase, molybdopterin binding subunit; Region: xanthine_xdhB; TIGR02965
926570003068	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570003069	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570003070	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
926570003071	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
926570003072	XdhC Rossmann domain; Region: XdhC_C; pfam13478
926570003073	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
926570003074	active site
926570003075	homotetramer interface [polypeptide binding]; other site
926570003076	Predicted membrane protein [Function unknown]; Region: COG3748
926570003077	Protein of unknown function (DUF989); Region: DUF989; pfam06181
926570003078	Cytochrome c; Region: Cytochrom_C; pfam00034
926570003079	OHCU decarboxylase; Region: OHCU_decarbox; pfam09349
926570003080	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
926570003081	guanine deaminase; Provisional; Region: PRK09228
926570003082	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
926570003083	active site
926570003084	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
926570003085	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
926570003086	tetramer interface [polypeptide binding]; other site
926570003087	heme binding pocket [chemical binding]; other site
926570003088	NADPH binding site [chemical binding]; other site
926570003089	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926570003090	Zn2+ binding site [ion binding]; other site
926570003091	Mg2+ binding site [ion binding]; other site
926570003092	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
926570003093	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
926570003094	conserved cys residue [active]
926570003095	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570003096	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570003097	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926570003098	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
926570003099	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926570003100	Protein of unknown function, DUF1537; Region: DUF1537; pfam07005
926570003101	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
926570003102	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
926570003103	Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type I periplasmic binding protein superfamily; Region: PBP1_ABC_sugar_binding_like_1; cd06300
926570003104	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570003105	putative ligand binding site [chemical binding]; other site
926570003106	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570003107	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570003108	Walker A/P-loop; other site
926570003109	ATP binding site [chemical binding]; other site
926570003110	Q-loop/lid; other site
926570003111	ABC transporter signature motif; other site
926570003112	Walker B; other site
926570003113	D-loop; other site
926570003114	H-loop/switch region; other site
926570003115	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570003116	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570003117	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570003118	TM-ABC transporter signature motif; other site
926570003119	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570003120	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570003121	TM-ABC transporter signature motif; other site
926570003122	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
926570003123	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
926570003124	Walker A/P-loop; other site
926570003125	ATP binding site [chemical binding]; other site
926570003126	Q-loop/lid; other site
926570003127	ABC transporter signature motif; other site
926570003128	Walker B; other site
926570003129	D-loop; other site
926570003130	H-loop/switch region; other site
926570003131	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
926570003132	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570003133	dimer interface [polypeptide binding]; other site
926570003134	conserved gate region; other site
926570003135	putative PBP binding loops; other site
926570003136	ABC-ATPase subunit interface; other site
926570003137	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926570003138	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926570003139	substrate binding pocket [chemical binding]; other site
926570003140	membrane-bound complex binding site; other site
926570003141	hinge residues; other site
926570003142	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
926570003143	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
926570003144	Multicopper oxidase; Region: Cu-oxidase; pfam00394
926570003145	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
926570003146	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
926570003147	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
926570003148	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
926570003149	Cation efflux family; Region: Cation_efflux; cl00316
926570003150	Helix-Turn-Helix DNA binding domain of the CadR- and PbrR-like transcription regulators; Region: HTH_CadR-PbrR-like; cd04785
926570003151	DNA binding residues [nucleotide binding]
926570003152	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
926570003153	dimer interface [polypeptide binding]; other site
926570003154	putative metal binding site [ion binding]; other site
926570003155	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
926570003156	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
926570003157	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
926570003158	putative metal binding site [ion binding]; other site
926570003159	putative homodimer interface [polypeptide binding]; other site
926570003160	putative homotetramer interface [polypeptide binding]; other site
926570003161	putative homodimer-homodimer interface [polypeptide binding]; other site
926570003162	putative allosteric switch controlling residues; other site
926570003163	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
926570003164	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570003165	catalytic loop [active]
926570003166	iron binding site [ion binding]; other site
926570003167	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926570003168	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570003169	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570003170	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570003171	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
926570003172	putative oxidoreductase; Provisional; Region: PRK11579
926570003173	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570003174	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570003175	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
926570003176	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
926570003177	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
926570003178	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
926570003179	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926570003180	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
926570003181	Soluble P-type ATPase [General function prediction only]; Region: COG4087
926570003182	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
926570003183	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
926570003184	NADH dehydrogenase subunit B; Validated; Region: PRK06411
926570003185	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
926570003186	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
926570003187	NADH dehydrogenase subunit D; Validated; Region: PRK06075
926570003188	NADH dehydrogenase subunit E; Validated; Region: PRK07539
926570003189	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
926570003190	putative dimer interface [polypeptide binding]; other site
926570003191	[2Fe-2S] cluster binding site [ion binding]; other site
926570003192	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
926570003193	SLBB domain; Region: SLBB; pfam10531
926570003194	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
926570003195	NADH-quinone oxidoreductase, chain G; Region: NuoG; TIGR01973
926570003196	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570003197	catalytic loop [active]
926570003198	iron binding site [ion binding]; other site
926570003199	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
926570003200	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
926570003201	[4Fe-4S] binding site [ion binding]; other site
926570003202	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
926570003203	molybdopterin cofactor binding site; other site
926570003204	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
926570003205	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
926570003206	4Fe-4S binding domain; Region: Fer4; pfam00037
926570003207	4Fe-4S binding domain; Region: Fer4; pfam00037
926570003208	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
926570003209	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
926570003210	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
926570003211	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
926570003212	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570003213	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
926570003214	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570003215	NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; Region: NuoN; COG1007
926570003216	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570003217	FOG: CBS domain [General function prediction only]; Region: COG0517
926570003218	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623
926570003219	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570003220	PAS fold; Region: PAS_3; pfam08447
926570003221	putative active site [active]
926570003222	heme pocket [chemical binding]; other site
926570003223	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570003224	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570003225	metal binding site [ion binding]; metal-binding site
926570003226	active site
926570003227	I-site; other site
926570003228	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570003229	Methyltransferase domain; Region: Methyltransf_31; pfam13847
926570003230	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570003231	S-adenosylmethionine binding site [chemical binding]; other site
926570003232	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570003233	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570003234	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570003235	dimerization interface [polypeptide binding]; other site
926570003236	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
926570003237	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
926570003238	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
926570003239	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
926570003240	cytochrome o ubiquinol oxidase, subunit I; Region: CyoB; TIGR02843
926570003241	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
926570003242	Subunit I/III interface [polypeptide binding]; other site
926570003243	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
926570003244	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
926570003245	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926570003246	DNA binding residues [nucleotide binding]
926570003247	Protein of unknown function (DUF1109); Region: DUF1109; cl02071
926570003248	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
926570003249	tetramer interface [polypeptide binding]; other site
926570003250	active site
926570003251	Mg2+/Mn2+ binding site [ion binding]; other site
926570003252	isocitrate lyase; Region: PLN02892
926570003253	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926570003254	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926570003255	Bacterial transcriptional repressor; Region: TetR; pfam13972
926570003256	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
926570003257	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
926570003258	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570003259	short chain dehydrogenase; Provisional; Region: PRK06181
926570003260	NAD(P) binding site [chemical binding]; other site
926570003261	active site
926570003262	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926570003263	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
926570003264	Uncharacterized protein conserved in bacteria (DUF2320); Region: DUF2320; pfam10082
926570003265	fumarylacetoacetase; Region: PLN02856
926570003266	Domain of unknown function (DUF1969); Region: DUF1969; pfam09298
926570003267	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
926570003268	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570003269	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570003270	nitrile hydratase, beta subunit; Region: nitrile_beta; TIGR03888
926570003271	nitrile hydratase, beta subunit; Region: nitrile_beta; TIGR03888
926570003272	Nitrile hydratase, alpha chain; Region: NHase_alpha; pfam02979
926570003273	NHLP leader peptide domain; Region: TOMM_pelo; TIGR03793
926570003274	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
926570003275	Mechanosensitive ion channel; Region: MS_channel; pfam00924
926570003276	Phosphate transporter family; Region: PHO4; cl00396
926570003277	arsenical resistance protein ArsH; Region: resist_ArsH; TIGR02690
926570003278	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
926570003279	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570003280	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570003281	TM-ABC transporter signature motif; other site
926570003282	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570003283	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570003284	Walker A/P-loop; other site
926570003285	ATP binding site [chemical binding]; other site
926570003286	Q-loop/lid; other site
926570003287	ABC transporter signature motif; other site
926570003288	Walker B; other site
926570003289	D-loop; other site
926570003290	H-loop/switch region; other site
926570003291	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570003292	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570003293	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570003294	TM-ABC transporter signature motif; other site
926570003295	Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type I periplasmic binding protein superfamily; Region: PBP1_ABC_sugar_binding_like_1; cd06300
926570003296	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570003297	putative ligand binding site [chemical binding]; other site
926570003298	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
926570003299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
926570003300	Ribulose 1,5-bisphosphate carboxylase, large subunit [Carbohydrate transport and metabolism]; Region: RbcL; COG1850
926570003301	Ribulose bisphosphate carboxylase like proteins from nonphototrophic bacteria; Region: RLP_NonPhot; cd08207
926570003302	dimer interface [polypeptide binding]; other site
926570003303	active site
926570003304	catalytic residue [active]
926570003305	metal binding site [ion binding]; metal-binding site
926570003306	transcriptional regulator NanR; Provisional; Region: PRK03837
926570003307	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570003308	DNA-binding site [nucleotide binding]; DNA binding site
926570003309	FCD domain; Region: FCD; pfam07729
926570003310	Predicted periplasmic lipoprotein (DUF2291); Region: DUF2291; pfam10054
926570003311	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570003312	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570003313	Walker A/P-loop; other site
926570003314	ATP binding site [chemical binding]; other site
926570003315	Q-loop/lid; other site
926570003316	ABC transporter signature motif; other site
926570003317	Walker B; other site
926570003318	D-loop; other site
926570003319	H-loop/switch region; other site
926570003320	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570003321	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570003322	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570003323	TM-ABC transporter signature motif; other site
926570003324	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
926570003325	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570003326	ligand binding site [chemical binding]; other site
926570003327	dimerization interface [polypeptide binding]; other site
926570003328	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570003329	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570003330	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570003331	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570003332	binding surface
926570003333	TPR motif; other site
926570003334	TPR repeat; Region: TPR_11; pfam13414
926570003335	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570003336	TPR repeat; Region: TPR_11; pfam13414
926570003337	binding surface
926570003338	TPR motif; other site
926570003339	TPR repeat; Region: TPR_11; pfam13414
926570003340	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570003341	binding surface
926570003342	TPR motif; other site
926570003343	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570003344	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
926570003345	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570003346	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570003347	catalytic residue [active]
926570003348	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
926570003349	Fe-S cluster binding site [ion binding]; other site
926570003350	active site
926570003351	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
926570003352	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926570003353	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
926570003354	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
926570003355	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570003356	Coenzyme A binding pocket [chemical binding]; other site
926570003357	dihydrodipicolinate reductase; Provisional; Region: PRK00048
926570003358	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
926570003359	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
926570003360	S-adenosylmethionine synthetase; Validated; Region: PRK05250
926570003361	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
926570003362	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
926570003363	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
926570003364	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
926570003365	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926570003366	Periplasmic solute-binding domain of active transport proteins that belong to the type I periplasmic binding fold protein family; Region: PBP1_SBP_like_1; cd06327
926570003367	putative ligand binding site [chemical binding]; other site
926570003368	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926570003369	TM-ABC transporter signature motif; other site
926570003370	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926570003371	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926570003372	TM-ABC transporter signature motif; other site
926570003373	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570003374	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926570003375	Walker A/P-loop; other site
926570003376	ATP binding site [chemical binding]; other site
926570003377	Q-loop/lid; other site
926570003378	ABC transporter signature motif; other site
926570003379	Walker B; other site
926570003380	D-loop; other site
926570003381	H-loop/switch region; other site
926570003382	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570003383	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926570003384	Walker A/P-loop; other site
926570003385	ATP binding site [chemical binding]; other site
926570003386	Q-loop/lid; other site
926570003387	ABC transporter signature motif; other site
926570003388	Walker B; other site
926570003389	D-loop; other site
926570003390	H-loop/switch region; other site
926570003391	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570003392	putative substrate translocation pore; other site
926570003393	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
926570003394	Ribbon-helix-helix domain; Region: RHH_4; pfam13467
926570003395	hopanoid biosynthesis associated RND transporter like protein HpnN; Region: HpnN; TIGR03480
926570003396	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
926570003397	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
926570003398	TAP-like protein; Region: Abhydrolase_4; pfam08386
926570003399	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926570003400	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926570003401	inhibitor-cofactor binding pocket; inhibition site
926570003402	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570003403	catalytic residue [active]
926570003404	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
926570003405	Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719
926570003406	NAD(P) binding site [chemical binding]; other site
926570003407	homodimer interface [polypeptide binding]; other site
926570003408	substrate binding site [chemical binding]; other site
926570003409	active site
926570003410	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
926570003411	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
926570003412	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
926570003413	NAD(P) binding site [chemical binding]; other site
926570003414	catalytic residues [active]
926570003415	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
926570003416	NAD(P) binding site [chemical binding]; other site
926570003417	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
926570003418	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
926570003419	motif 1; other site
926570003420	active site
926570003421	motif 2; other site
926570003422	motif 3; other site
926570003423	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
926570003424	DHHA1 domain; Region: DHHA1; pfam02272
926570003425	Domain of unknown function (DUF4393); Region: DUF4393; pfam14337
926570003426	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570003427	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570003428	recombinase A; Provisional; Region: recA; PRK09354
926570003429	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
926570003430	hexamer interface [polypeptide binding]; other site
926570003431	Walker A motif; other site
926570003432	ATP binding site [chemical binding]; other site
926570003433	Walker B motif; other site
926570003434	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
926570003435	active site
926570003436	catalytic residues [active]
926570003437	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570003438	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570003439	active site
926570003440	Autotransporter beta-domain; Region: Autotransporter; smart00869
926570003441	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
926570003442	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
926570003443	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
926570003444	putative homodimer interface [polypeptide binding]; other site
926570003445	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
926570003446	heterodimer interface [polypeptide binding]; other site
926570003447	homodimer interface [polypeptide binding]; other site
926570003448	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926570003449	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926570003450	(R)-hydratase [(R)-specific enoyl-CoA hydratase]. Catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway.  The structure of the monomer includes a five-strand antiparallel...; Region: R_hydratase_like; cd03441
926570003451	active site
926570003452	catalytic site [active]
926570003453	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
926570003454	tetramer interface; other site
926570003455	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
926570003456	active site
926570003457	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
926570003458	active site
926570003459	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
926570003460	substrate binding site [chemical binding]; other site
926570003461	metal binding site [ion binding]; metal-binding site
926570003462	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
926570003463	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
926570003464	active site
926570003465	HIGH motif; other site
926570003466	dimer interface [polypeptide binding]; other site
926570003467	KMSKS motif; other site
926570003468	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
926570003469	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
926570003470	CHAP domain; Region: CHAP; cl17642
926570003471	Putative phosphatase (DUF442); Region: DUF442; cl17385
926570003472	Domain of unknown function (DUF4167); Region: DUF4167; pfam13763
926570003473	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
926570003474	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926570003475	peptide chain release factor 1; Validated; Region: prfA; PRK00591
926570003476	PCRF domain; Region: PCRF; pfam03462
926570003477	RF-1 domain; Region: RF-1; pfam00472
926570003478	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
926570003479	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
926570003480	dimer interface [polypeptide binding]; other site
926570003481	motif 1; other site
926570003482	active site
926570003483	motif 2; other site
926570003484	motif 3; other site
926570003485	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
926570003486	anticodon binding site; other site
926570003487	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
926570003488	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
926570003489	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
926570003490	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
926570003491	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570003492	non-specific DNA binding site [nucleotide binding]; other site
926570003493	salt bridge; other site
926570003494	sequence-specific DNA binding site [nucleotide binding]; other site
926570003495	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
926570003496	Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms]; Region: PtsP; COG3605
926570003497	GAF domain; Region: GAF; pfam01590
926570003498	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
926570003499	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926570003500	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926570003501	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
926570003502	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
926570003503	FMN binding site [chemical binding]; other site
926570003504	substrate binding site [chemical binding]; other site
926570003505	putative catalytic residue [active]
926570003506	aspartate kinase; Reviewed; Region: PRK06635
926570003507	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
926570003508	putative nucleotide binding site [chemical binding]; other site
926570003509	putative catalytic residues [active]
926570003510	putative Mg ion binding site [ion binding]; other site
926570003511	putative aspartate binding site [chemical binding]; other site
926570003512	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
926570003513	putative allosteric regulatory site; other site
926570003514	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
926570003515	putative allosteric regulatory residue; other site
926570003516	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
926570003517	Methyltransferase domain; Region: Methyltransf_11; pfam08241
926570003518	putative choline sulfate-utilization transcription factor; Region: chol_sulf_TF; TIGR03418
926570003519	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570003520	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570003521	dimerization interface [polypeptide binding]; other site
926570003522	Sulfatase; Region: Sulfatase; cl17466
926570003523	choline-sulfatase; Region: chol_sulfatase; TIGR03417
926570003524	Choline sulfatase enzyme C terminal; Region: Choline_sulf_C; pfam12411
926570003525	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
926570003526	AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136
926570003527	conserved cys residue [active]
926570003528	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570003529	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
926570003530	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
926570003531	[2Fe-2S] cluster binding site [ion binding]; other site
926570003532	C-terminal catalytic domain of GbcA (glycine betaine catabolism A) from Pseudomonas aeruginosa PAO1 and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_GbcA-like; cd08884
926570003533	putative alpha subunit interface [polypeptide binding]; other site
926570003534	putative active site [active]
926570003535	putative substrate binding site [chemical binding]; other site
926570003536	Fe binding site [ion binding]; other site
926570003537	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
926570003538	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
926570003539	FAD binding pocket [chemical binding]; other site
926570003540	FAD binding motif [chemical binding]; other site
926570003541	phosphate binding motif [ion binding]; other site
926570003542	beta-alpha-beta structure motif; other site
926570003543	NAD binding pocket [chemical binding]; other site
926570003544	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570003545	catalytic loop [active]
926570003546	iron binding site [ion binding]; other site
926570003547	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
926570003548	AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136
926570003549	conserved cys residue [active]
926570003550	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570003551	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570003552	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
926570003553	Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_3_FMN; cd04734
926570003554	putative active site [active]
926570003555	putative FMN binding site [chemical binding]; other site
926570003556	putative substrate binding site [chemical binding]; other site
926570003557	putative catalytic residue [active]
926570003558	Domain of unknown function (DUF3483); Region: DUF3483; pfam11982
926570003559	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
926570003560	4Fe-4S binding domain; Region: Fer4; pfam00037
926570003561	Cysteine-rich domain; Region: CCG; pfam02754
926570003562	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
926570003563	Ligand Binding Site [chemical binding]; other site
926570003564	Electron transfer flavoprotein domain; Region: ETF; smart00893
926570003565	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
926570003566	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
926570003567	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
926570003568	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
926570003569	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
926570003570	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510
926570003571	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
926570003572	Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; Region: GcvT; COG0404
926570003573	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
926570003574	Sarcosine oxidase, delta subunit family; Region: SoxD; cl01767
926570003575	sarcosine oxidase, beta subunit family, heterotetrameric form; Region: soxB; TIGR01373
926570003576	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926570003577	choline dehydrogenase; Validated; Region: PRK02106
926570003578	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
926570003579	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
926570003580	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
926570003581	NAD(P) binding site [chemical binding]; other site
926570003582	catalytic residues [active]
926570003583	choline ABC transporter, ATP-binding protein; Region: ABC_choXWV_ATP; TIGR03415
926570003584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570003585	Walker A/P-loop; other site
926570003586	ATP binding site [chemical binding]; other site
926570003587	Q-loop/lid; other site
926570003588	ABC transporter signature motif; other site
926570003589	Walker B; other site
926570003590	D-loop; other site
926570003591	H-loop/switch region; other site
926570003592	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570003593	dimer interface [polypeptide binding]; other site
926570003594	conserved gate region; other site
926570003595	putative PBP binding loops; other site
926570003596	ABC-ATPase subunit interface; other site
926570003597	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
926570003598	choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414
926570003599	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
926570003600	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
926570003601	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926570003602	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
926570003603	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926570003604	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570003605	dimer interface [polypeptide binding]; other site
926570003606	conserved gate region; other site
926570003607	putative PBP binding loops; other site
926570003608	ABC-ATPase subunit interface; other site
926570003609	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
926570003610	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570003611	Walker A/P-loop; other site
926570003612	ATP binding site [chemical binding]; other site
926570003613	Q-loop/lid; other site
926570003614	ABC transporter signature motif; other site
926570003615	Walker B; other site
926570003616	D-loop; other site
926570003617	H-loop/switch region; other site
926570003618	TOBE domain; Region: TOBE_2; pfam08402
926570003619	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926570003620	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
926570003621	active site
926570003622	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
926570003623	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
926570003624	active site
926570003625	metal binding site [ion binding]; metal-binding site
926570003626	hexamer interface [polypeptide binding]; other site
926570003627	Transcriptional regulators [Transcription]; Region: MarR; COG1846
926570003628	MarR family; Region: MarR; pfam01047
926570003629	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570003630	Coenzyme A binding pocket [chemical binding]; other site
926570003631	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
926570003632	Ligand binding site; other site
926570003633	Putative Catalytic site; other site
926570003634	DXD motif; other site
926570003635	Uncharacterized conserved protein [Function unknown]; Region: COG0398
926570003636	flagellar motor switch protein FliM; Region: fliM_switch; TIGR01397
926570003637	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
926570003638	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
926570003639	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
926570003640	active site
926570003641	HIGH motif; other site
926570003642	KMSKS motif; other site
926570003643	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
926570003644	tRNA binding surface [nucleotide binding]; other site
926570003645	anticodon binding site; other site
926570003646	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
926570003647	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
926570003648	Walker A motif; other site
926570003649	ATP binding site [chemical binding]; other site
926570003650	Walker B motif; other site
926570003651	thymidylate kinase; Validated; Region: tmk; PRK00698
926570003652	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
926570003653	TMP-binding site; other site
926570003654	ATP-binding site [chemical binding]; other site
926570003655	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; cl04011
926570003656	Transglycosylase SLT domain; Region: SLT_2; pfam13406
926570003657	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570003658	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570003659	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
926570003660	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
926570003661	catalytic residues [active]
926570003662	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570003663	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570003664	metal binding site [ion binding]; metal-binding site
926570003665	active site
926570003666	I-site; other site
926570003667	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570003668	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
926570003669	ThiC-associated domain; Region: ThiC-associated; pfam13667
926570003670	ThiC family; Region: ThiC; pfam01964
926570003671	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
926570003672	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926570003673	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
926570003674	thiS-thiF/thiG interaction site; other site
926570003675	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
926570003676	ThiS interaction site; other site
926570003677	putative active site [active]
926570003678	tetramer interface [polypeptide binding]; other site
926570003679	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570003680	dimerization interface [polypeptide binding]; other site
926570003681	putative DNA binding site [nucleotide binding]; other site
926570003682	putative Zn2+ binding site [ion binding]; other site
926570003683	Predicted transporter component [General function prediction only]; Region: COG2391
926570003684	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
926570003685	seryl-tRNA synthetase; Provisional; Region: PRK05431
926570003686	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
926570003687	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
926570003688	dimer interface [polypeptide binding]; other site
926570003689	active site
926570003690	motif 1; other site
926570003691	motif 2; other site
926570003692	motif 3; other site
926570003693	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
926570003694	twin arginine-targeting protein translocase TatB; Region: tatB; TIGR01410
926570003695	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
926570003696	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
926570003697	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
926570003698	Peptidase family M50; Region: Peptidase_M50; pfam02163
926570003699	active site
926570003700	putative substrate binding region [chemical binding]; other site
926570003701	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
926570003702	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
926570003703	Sporulation related domain; Region: SPOR; pfam05036
926570003704	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
926570003705	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
926570003706	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
926570003707	active site
926570003708	HIGH motif; other site
926570003709	KMSK motif region; other site
926570003710	tRNA binding surface [nucleotide binding]; other site
926570003711	DALR anticodon binding domain; Region: DALR_1; smart00836
926570003712	anticodon binding site; other site
926570003713	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
926570003714	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926570003715	Zn2+ binding site [ion binding]; other site
926570003716	Mg2+ binding site [ion binding]; other site
926570003717	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
926570003718	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
926570003719	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
926570003720	putative catalytic site [active]
926570003721	putative phosphate binding site [ion binding]; other site
926570003722	active site
926570003723	metal binding site A [ion binding]; metal-binding site
926570003724	DNA binding site [nucleotide binding]
926570003725	putative AP binding site [nucleotide binding]; other site
926570003726	putative metal binding site B [ion binding]; other site
926570003727	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
926570003728	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926570003729	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570003730	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
926570003731	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570003732	ABC transporter; Region: ABC_tran_2; pfam12848
926570003733	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570003734	Predicted membrane protein [Function unknown]; Region: COG3431
926570003735	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
926570003736	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926570003737	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926570003738	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926570003739	Walker A/P-loop; other site
926570003740	ATP binding site [chemical binding]; other site
926570003741	Q-loop/lid; other site
926570003742	ABC transporter signature motif; other site
926570003743	Walker B; other site
926570003744	D-loop; other site
926570003745	H-loop/switch region; other site
926570003746	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
926570003747	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926570003748	FtsX-like permease family; Region: FtsX; pfam02687
926570003749	prolyl-tRNA synthetase; Provisional; Region: PRK12325
926570003750	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
926570003751	dimer interface [polypeptide binding]; other site
926570003752	motif 1; other site
926570003753	active site
926570003754	motif 2; other site
926570003755	motif 3; other site
926570003756	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
926570003757	anticodon binding site; other site
926570003758	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
926570003759	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
926570003760	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926570003761	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
926570003762	pantothenate kinase; Reviewed; Region: PRK13318
926570003763	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
926570003764	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
926570003765	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
926570003766	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570003767	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
926570003768	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570003769	NADH dehydrogenase subunit 5; Provisional; Region: ND5; MTH00032
926570003770	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
926570003771	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570003772	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
926570003773	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
926570003774	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
926570003775	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
926570003776	4Fe-4S binding domain; Region: Fer4; pfam00037
926570003777	4Fe-4S binding domain; Region: Fer4; pfam00037
926570003778	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
926570003779	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
926570003780	NADH dehydrogenase subunit G; Validated; Region: PRK09130
926570003781	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570003782	catalytic loop [active]
926570003783	iron binding site [ion binding]; other site
926570003784	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
926570003785	MopB_Res_Cmplx1_Nad11: The second domain of the Nad11/75-kDa subunit of the NADH-quinone oxidoreductase/respiratory complex I/NADH dehydrogenase-1(NDH-1) of eukaryotes and the Nqo3/G subunit of alphaproteobacteria NDH-1. The NADH-quinone oxidoreductase...; Region: MopB_Res-Cmplx1_Nad11; cd02773
926570003786	Domain of unknown function (DUF1982); Region: DUF1982; pfam09326
926570003787	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
926570003788	SLBB domain; Region: SLBB; pfam10531
926570003789	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
926570003790	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
926570003791	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
926570003792	putative dimer interface [polypeptide binding]; other site
926570003793	[2Fe-2S] cluster binding site [ion binding]; other site
926570003794	NADH dehydrogenase subunit D; Validated; Region: PRK06075
926570003795	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
926570003796	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
926570003797	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
926570003798	NADH dehydrogenase subunit B; Validated; Region: PRK06411
926570003799	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
926570003800	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
926570003801	IHF dimer interface [polypeptide binding]; other site
926570003802	IHF - DNA interface [nucleotide binding]; other site
926570003803	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
926570003804	Found in ATP-dependent protease La (LON); Region: LON; smart00464
926570003805	Found in ATP-dependent protease La (LON); Region: LON; smart00464
926570003806	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570003807	Walker A motif; other site
926570003808	ATP binding site [chemical binding]; other site
926570003809	Walker B motif; other site
926570003810	arginine finger; other site
926570003811	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
926570003812	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
926570003813	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
926570003814	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570003815	Walker A motif; other site
926570003816	ATP binding site [chemical binding]; other site
926570003817	Walker B motif; other site
926570003818	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
926570003819	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
926570003820	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
926570003821	oligomer interface [polypeptide binding]; other site
926570003822	active site residues [active]
926570003823	trigger factor; Provisional; Region: tig; PRK01490
926570003824	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
926570003825	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
926570003826	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
926570003827	active site
926570003828	catalytic triad [active]
926570003829	oxyanion hole [active]
926570003830	Autotransporter beta-domain; Region: Autotransporter; smart00869
926570003831	PII uridylyl-transferase; Provisional; Region: PRK05092
926570003832	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
926570003833	metal binding triad; other site
926570003834	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
926570003835	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
926570003836	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
926570003837	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
926570003838	MutS domain I; Region: MutS_I; pfam01624
926570003839	MutS domain III; Region: MutS_III; pfam05192
926570003840	MutS domain V; Region: MutS_V; pfam00488
926570003841	Walker A/P-loop; other site
926570003842	ATP binding site [chemical binding]; other site
926570003843	Q-loop/lid; other site
926570003844	ABC transporter signature motif; other site
926570003845	Walker B; other site
926570003846	D-loop; other site
926570003847	H-loop/switch region; other site
926570003848	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
926570003849	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
926570003850	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
926570003851	catalytic site [active]
926570003852	subunit interface [polypeptide binding]; other site
926570003853	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
926570003854	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926570003855	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
926570003856	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
926570003857	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926570003858	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926570003859	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
926570003860	IMP binding site; other site
926570003861	dimer interface [polypeptide binding]; other site
926570003862	partial ornithine binding site; other site
926570003863	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
926570003864	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
926570003865	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
926570003866	threonine dehydratase; Provisional; Region: PRK07334
926570003867	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
926570003868	tetramer interface [polypeptide binding]; other site
926570003869	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570003870	catalytic residue [active]
926570003871	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
926570003872	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
926570003873	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
926570003874	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
926570003875	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
926570003876	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
926570003877	active site
926570003878	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
926570003879	phosphoglyceromutase; Provisional; Region: PRK05434
926570003880	Peptidase family M23; Region: Peptidase_M23; pfam01551
926570003881	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
926570003882	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
926570003883	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
926570003884	protein binding site [polypeptide binding]; other site
926570003885	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
926570003886	Catalytic dyad [active]
926570003887	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
926570003888	NodB motif; other site
926570003889	putative active site [active]
926570003890	putative catalytic site [active]
926570003891	Zn binding site [ion binding]; other site
926570003892	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
926570003893	putative active site [active]
926570003894	Ap4A binding site [chemical binding]; other site
926570003895	nudix motif; other site
926570003896	putative metal binding site [ion binding]; other site
926570003897	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
926570003898	GMP synthase; Reviewed; Region: guaA; PRK00074
926570003899	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
926570003900	AMP/PPi binding site [chemical binding]; other site
926570003901	candidate oxyanion hole; other site
926570003902	catalytic triad [active]
926570003903	potential glutamine specificity residues [chemical binding]; other site
926570003904	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
926570003905	ATP Binding subdomain [chemical binding]; other site
926570003906	Ligand Binding sites [chemical binding]; other site
926570003907	Dimerization subdomain; other site
926570003908	integrase; Provisional; Region: PRK09692
926570003909	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
926570003910	active site
926570003911	Int/Topo IB signature motif; other site
926570003912	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926570003913	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
926570003914	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
926570003915	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570003916	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570003917	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570003918	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570003919	AAA domain; Region: AAA_25; pfam13481
926570003920	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
926570003921	Walker A motif; other site
926570003922	ATP binding site [chemical binding]; other site
926570003923	Walker B motif; other site
926570003924	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570003925	Protein of unknown function (DUF3095); Region: DUF3095; pfam11294
926570003926	MULE transposase domain; Region: MULE; pfam10551
926570003927	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
926570003928	Replication protein C (RepC); Region: RepC; pfam06504
926570003929	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570003930	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570003931	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926570003932	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570003933	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570003934	conjugal transfer relaxosome component TraJ; Provisional; Region: PRK13877
926570003935	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570003936	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570003937	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
926570003938	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
926570003939	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
926570003940	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
926570003941	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
926570003942	N-terminal plug; other site
926570003943	ligand-binding site [chemical binding]; other site
926570003944	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
926570003945	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
926570003946	Phosphoesterase family; Region: Phosphoesterase; pfam04185
926570003947	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
926570003948	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
926570003949	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
926570003950	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
926570003951	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
926570003952	Walker A motif; other site
926570003953	ATP binding site [chemical binding]; other site
926570003954	Walker B motif; other site
926570003955	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
926570003956	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
926570003957	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
926570003958	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
926570003959	Type II secretion system (T2SS), protein M subtype b; Region: T2SM_b; pfam10741
926570003960	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
926570003961	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
926570003962	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
926570003963	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
926570003964	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
926570003965	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570003966	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570003967	catalytic residue [active]
926570003968	Phosphoesterase family; Region: Phosphoesterase; pfam04185
926570003969	Phosphoesterase family; Region: Phosphoesterase; pfam04185
926570003970	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570003971	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
926570003972	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
926570003973	catalytic residues [active]
926570003974	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
926570003975	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
926570003976	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
926570003977	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
926570003978	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
926570003979	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
926570003980	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
926570003981	GatB domain; Region: GatB_Yqey; smart00845
926570003982	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
926570003983	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926570003984	Cu(I) binding site [ion binding]; other site
926570003985	Cytochrome c; Region: Cytochrom_C; pfam00034
926570003986	Protein of unknown function (DUF461); Region: DUF461; pfam04314
926570003987	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
926570003988	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
926570003989	Cu(I) binding site [ion binding]; other site
926570003990	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926570003991	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
926570003992	Trehalose-phosphatase; Region: Trehalose_PPase; pfam02358
926570003993	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
926570003994	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
926570003995	active site
926570003996	homotetramer interface [polypeptide binding]; other site
926570003997	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
926570003998	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
926570003999	active site
926570004000	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
926570004001	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
926570004002	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
926570004003	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
926570004004	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926570004005	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
926570004006	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926570004007	DNA binding residues [nucleotide binding]
926570004008	DNA primase; Validated; Region: dnaG; PRK05667
926570004009	CHC2 zinc finger; Region: zf-CHC2; pfam01807
926570004010	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
926570004011	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
926570004012	active site
926570004013	metal binding site [ion binding]; metal-binding site
926570004014	interdomain interaction site; other site
926570004015	Yqey-like protein; Region: YqeY; cl17540
926570004016	PAS domain; Region: PAS_9; pfam13426
926570004017	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570004018	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570004019	metal binding site [ion binding]; metal-binding site
926570004020	active site
926570004021	I-site; other site
926570004022	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570004023	Glutaryl-CoA dehydrogenase; Region: GCD; cd01151
926570004024	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570004025	FAD binding site [chemical binding]; other site
926570004026	substrate binding pocket [chemical binding]; other site
926570004027	catalytic base [active]
926570004028	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
926570004029	DEAD-like helicases superfamily; Region: DEXDc; smart00487
926570004030	ATP binding site [chemical binding]; other site
926570004031	Mg++ binding site [ion binding]; other site
926570004032	motif III; other site
926570004033	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570004034	nucleotide binding region [chemical binding]; other site
926570004035	ATP-binding site [chemical binding]; other site
926570004036	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
926570004037	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926570004038	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570004039	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
926570004040	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570004041	dimer interface [polypeptide binding]; other site
926570004042	phosphorylation site [posttranslational modification]
926570004043	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570004044	ATP binding site [chemical binding]; other site
926570004045	Mg2+ binding site [ion binding]; other site
926570004046	G-X-G motif; other site
926570004047	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570004048	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570004049	active site
926570004050	phosphorylation site [posttranslational modification]
926570004051	intermolecular recognition site; other site
926570004052	dimerization interface [polypeptide binding]; other site
926570004053	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570004054	DNA binding site [nucleotide binding]
926570004055	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926570004056	MarR family; Region: MarR_2; pfam12802
926570004057	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
926570004058	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
926570004059	homodimer interface [polypeptide binding]; other site
926570004060	substrate-cofactor binding pocket; other site
926570004061	catalytic residue [active]
926570004062	Domain of unknown function (DUF202); Region: DUF202; cl09954
926570004063	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
926570004064	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570004065	putative substrate translocation pore; other site
926570004066	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
926570004067	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
926570004068	catalytic triad [active]
926570004069	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
926570004070	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
926570004071	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
926570004072	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
926570004073	6-hydroxyhexanoate dehydrogenase; Region: 6_hydroxyhexanoate_dh_like; cd08240
926570004074	putative NAD(P) binding site [chemical binding]; other site
926570004075	catalytic Zn binding site [ion binding]; other site
926570004076	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570004077	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570004078	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
926570004079	dimerization interface [polypeptide binding]; other site
926570004080	formate dehydrogenase subunit gamma; Validated; Region: PRK05988
926570004081	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily, NAD-dependent formate dehydrogenase (FDH) gamma subunit; composed of proteins similar to the gamma subunit of NAD-linked FDH of Ralstonia eutropha, a...; Region: TRX_Fd_NuoE_FDH_gamma; cd03081
926570004082	putative dimer interface [polypeptide binding]; other site
926570004083	[2Fe-2S] cluster binding site [ion binding]; other site
926570004084	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570004085	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
926570004086	SLBB domain; Region: SLBB; pfam10531
926570004087	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
926570004088	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
926570004089	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570004090	catalytic loop [active]
926570004091	iron binding site [ion binding]; other site
926570004092	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
926570004093	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
926570004094	[4Fe-4S] binding site [ion binding]; other site
926570004095	molybdopterin cofactor binding site; other site
926570004096	This CD includes formate dehydrogenases (Fdh) H and N; nitrate reductases, Nap and Nas; and other related proteins. Formate dehydrogenase H is a component of the anaerobic formate hydrogen lyase complex  and catalyzes the reversible oxidation of formate...; Region: MopB_CT_Fdh-Nap-like; cd00508
926570004097	molybdopterin cofactor binding site; other site
926570004098	FdhD/NarQ family; Region: FdhD-NarQ; cl00659
926570004099	NADH-dependant formate dehydrogenase delta subunit FdsD; Region: FdsD; pfam11390
926570004100	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
926570004101	Protein of unknown function (DUF1491); Region: DUF1491; pfam07372
926570004102	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
926570004103	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
926570004104	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926570004105	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926570004106	Walker A/P-loop; other site
926570004107	ATP binding site [chemical binding]; other site
926570004108	Q-loop/lid; other site
926570004109	ABC transporter signature motif; other site
926570004110	Walker B; other site
926570004111	D-loop; other site
926570004112	H-loop/switch region; other site
926570004113	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926570004114	Binding-protein-dependent transport system inner membrane component; Region: BPD_transp_1; pfam00528
926570004115	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08159
926570004116	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
926570004117	NAD binding site [chemical binding]; other site
926570004118	homotetramer interface [polypeptide binding]; other site
926570004119	homodimer interface [polypeptide binding]; other site
926570004120	substrate binding site [chemical binding]; other site
926570004121	active site
926570004122	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
926570004123	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
926570004124	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
926570004125	cytosine deaminase; Validated; Region: PRK07572
926570004126	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
926570004127	active site
926570004128	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
926570004129	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
926570004130	substrate binding site [chemical binding]; other site
926570004131	hexamer interface [polypeptide binding]; other site
926570004132	metal binding site [ion binding]; metal-binding site
926570004133	probable Rubsico expression protein CbbX; Region: cbbX_cfxQ; TIGR02880
926570004134	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570004135	Walker A motif; other site
926570004136	ATP binding site [chemical binding]; other site
926570004137	Walker B motif; other site
926570004138	arginine finger; other site
926570004139	Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of photorespiration. Rubisco...; Region: RuBisCO_small; cd03527
926570004140	multimerization interface [polypeptide binding]; other site
926570004141	ribulose bisophosphate carboxylase; Reviewed; Region: rbcL; PRK04208
926570004142	Ribulose bisphosphate carboxylase large chain, Form I; Region: RuBisCO_large_I; cd08212
926570004143	homodimer interface [polypeptide binding]; other site
926570004144	active site
926570004145	heterodimer interface [polypeptide binding]; other site
926570004146	catalytic residue [active]
926570004147	metal binding site [ion binding]; metal-binding site
926570004148	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
926570004149	intersubunit interface [polypeptide binding]; other site
926570004150	active site
926570004151	zinc binding site [ion binding]; other site
926570004152	Na+ binding site [ion binding]; other site
926570004153	phosphoribulokinase; Provisional; Region: PRK15453
926570004154	active site
926570004155	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
926570004156	metal binding site [ion binding]; metal-binding site
926570004157	active site
926570004158	AAA domain; Region: AAA_31; pfam13614
926570004159	This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111
926570004160	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
926570004161	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
926570004162	dimer interface [polypeptide binding]; other site
926570004163	substrate binding site [chemical binding]; other site
926570004164	ATP binding site [chemical binding]; other site
926570004165	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14315
926570004166	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
926570004167	active site
926570004168	substrate binding site [chemical binding]; other site
926570004169	metal binding site [ion binding]; metal-binding site
926570004170	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
926570004171	dihydropteroate synthase; Region: DHPS; TIGR01496
926570004172	substrate binding pocket [chemical binding]; other site
926570004173	dimer interface [polypeptide binding]; other site
926570004174	inhibitor binding site; inhibition site
926570004175	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
926570004176	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
926570004177	GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043
926570004178	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
926570004179	putative C-terminal domain interface [polypeptide binding]; other site
926570004180	putative GSH binding site (G-site) [chemical binding]; other site
926570004181	putative dimer interface [polypeptide binding]; other site
926570004182	C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194
926570004183	putative substrate binding pocket (H-site) [chemical binding]; other site
926570004184	putative N-terminal domain interface [polypeptide binding]; other site
926570004185	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
926570004186	ligand binding site [chemical binding]; other site
926570004187	active site
926570004188	pterin-4-alpha-carbinolamine dehydratase; Validated; Region: phhB; PRK00823
926570004189	aromatic arch; other site
926570004190	DCoH dimer interaction site [polypeptide binding]; other site
926570004191	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
926570004192	DCoH tetramer interaction site [polypeptide binding]; other site
926570004193	substrate binding site [chemical binding]; other site
926570004194	hypothetical protein; Validated; Region: PRK09104
926570004195	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
926570004196	metal binding site [ion binding]; metal-binding site
926570004197	putative dimer interface [polypeptide binding]; other site
926570004198	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
926570004199	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
926570004200	Walker A/P-loop; other site
926570004201	ATP binding site [chemical binding]; other site
926570004202	Q-loop/lid; other site
926570004203	ABC transporter signature motif; other site
926570004204	Walker B; other site
926570004205	D-loop; other site
926570004206	H-loop/switch region; other site
926570004207	Uncharacterized protein family (UPF0014); Region: UPF0014; cl00424
926570004208	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
926570004209	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926570004210	PAS domain; Region: PAS_9; pfam13426
926570004211	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
926570004212	putative active site [active]
926570004213	heme pocket [chemical binding]; other site
926570004214	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570004215	dimer interface [polypeptide binding]; other site
926570004216	phosphorylation site [posttranslational modification]
926570004217	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570004218	ATP binding site [chemical binding]; other site
926570004219	G-X-G motif; other site
926570004220	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570004221	active site
926570004222	phosphorylation site [posttranslational modification]
926570004223	intermolecular recognition site; other site
926570004224	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926570004225	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570004226	Rod binding protein; Region: Rod-binding; pfam10135
926570004227	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
926570004228	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
926570004229	Class II flagellar assembly regulator; Region: FliX; pfam10768
926570004230	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
926570004231	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
926570004232	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
926570004233	nucleotide binding pocket [chemical binding]; other site
926570004234	K-X-D-G motif; other site
926570004235	catalytic site [active]
926570004236	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
926570004237	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
926570004238	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
926570004239	Dimer interface [polypeptide binding]; other site
926570004240	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
926570004241	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
926570004242	Walker A/P-loop; other site
926570004243	ATP binding site [chemical binding]; other site
926570004244	Q-loop/lid; other site
926570004245	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
926570004246	ABC transporter signature motif; other site
926570004247	Walker B; other site
926570004248	D-loop; other site
926570004249	H-loop/switch region; other site
926570004250	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
926570004251	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
926570004252	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
926570004253	RNA binding site [nucleotide binding]; other site
926570004254	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
926570004255	RNA binding site [nucleotide binding]; other site
926570004256	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
926570004257	RNA binding site [nucleotide binding]; other site
926570004258	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
926570004259	RNA binding site [nucleotide binding]; other site
926570004260	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
926570004261	RNA binding site [nucleotide binding]; other site
926570004262	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
926570004263	RNA binding site [nucleotide binding]; other site
926570004264	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926570004265	Trp docking motif [polypeptide binding]; other site
926570004266	active site
926570004267	PQQ-like domain; Region: PQQ_2; pfam13360
926570004268	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926570004269	GTP-binding protein Der; Reviewed; Region: PRK00093
926570004270	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
926570004271	G1 box; other site
926570004272	GTP/Mg2+ binding site [chemical binding]; other site
926570004273	Switch I region; other site
926570004274	G2 box; other site
926570004275	Switch II region; other site
926570004276	G3 box; other site
926570004277	G4 box; other site
926570004278	G5 box; other site
926570004279	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
926570004280	G1 box; other site
926570004281	GTP/Mg2+ binding site [chemical binding]; other site
926570004282	Switch I region; other site
926570004283	G2 box; other site
926570004284	G3 box; other site
926570004285	Switch II region; other site
926570004286	G4 box; other site
926570004287	G5 box; other site
926570004288	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
926570004289	argininosuccinate synthase; Provisional; Region: PRK13820
926570004290	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
926570004291	ANP binding site [chemical binding]; other site
926570004292	Substrate Binding Site II [chemical binding]; other site
926570004293	Substrate Binding Site I [chemical binding]; other site
926570004294	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926570004295	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926570004296	catalytic residues [active]
926570004297	argininosuccinate lyase; Provisional; Region: PRK00855
926570004298	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
926570004299	active sites [active]
926570004300	tetramer interface [polypeptide binding]; other site
926570004301	diaminopimelate decarboxylase; Region: lysA; TIGR01048
926570004302	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
926570004303	active site
926570004304	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926570004305	substrate binding site [chemical binding]; other site
926570004306	catalytic residues [active]
926570004307	dimer interface [polypeptide binding]; other site
926570004308	Domain of unknown function (DUF4175); Region: DUF4175; pfam13779
926570004309	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
926570004310	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
926570004311	Walker A/P-loop; other site
926570004312	ATP binding site [chemical binding]; other site
926570004313	Q-loop/lid; other site
926570004314	ABC transporter signature motif; other site
926570004315	Walker B; other site
926570004316	D-loop; other site
926570004317	H-loop/switch region; other site
926570004318	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
926570004319	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
926570004320	aspartate aminotransferase; Provisional; Region: PRK05764
926570004321	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570004322	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570004323	homodimer interface [polypeptide binding]; other site
926570004324	catalytic residue [active]
926570004325	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
926570004326	Class I ribonucleotide reductase; Region: RNR_I; cd01679
926570004327	active site
926570004328	dimer interface [polypeptide binding]; other site
926570004329	catalytic residues [active]
926570004330	effector binding site; other site
926570004331	R2 peptide binding site; other site
926570004332	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
926570004333	dimer interface [polypeptide binding]; other site
926570004334	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
926570004335	putative radical transfer pathway; other site
926570004336	diiron center [ion binding]; other site
926570004337	tyrosyl radical; other site
926570004338	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
926570004339	DNA methylase; Region: N6_N4_Mtase; cl17433
926570004340	Predicted amidohydrolase [General function prediction only]; Region: COG0388
926570004341	Pseudomonas sp. MCI3434 R-amidase and related proteins (putative class 13 nitrilases); Region: R-amidase_like; cd07576
926570004342	putative active site [active]
926570004343	catalytic triad [active]
926570004344	putative dimer interface [polypeptide binding]; other site
926570004345	hypothetical protein; Provisional; Region: PRK11281
926570004346	Predicted transcriptional regulator [Transcription]; Region: COG2932
926570004347	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
926570004348	Catalytic site [active]
926570004349	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
926570004350	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
926570004351	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
926570004352	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570004353	dihydroorotase; Validated; Region: pyrC; PRK09357
926570004354	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
926570004355	active site
926570004356	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
926570004357	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
926570004358	DNA protecting protein DprA; Region: dprA; TIGR00732
926570004359	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
926570004360	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
926570004361	active site
926570004362	interdomain interaction site; other site
926570004363	putative metal-binding site [ion binding]; other site
926570004364	nucleotide binding site [chemical binding]; other site
926570004365	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
926570004366	domain I; other site
926570004367	DNA binding groove [nucleotide binding]
926570004368	phosphate binding site [ion binding]; other site
926570004369	domain II; other site
926570004370	domain III; other site
926570004371	nucleotide binding site [chemical binding]; other site
926570004372	catalytic site [active]
926570004373	domain IV; other site
926570004374	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
926570004375	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
926570004376	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
926570004377	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
926570004378	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
926570004379	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
926570004380	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
926570004381	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
926570004382	active site
926570004383	HIGH motif; other site
926570004384	dimer interface [polypeptide binding]; other site
926570004385	KMSKS motif; other site
926570004386	Fe-S metabolism associated domain; Region: SufE; cl00951
926570004387	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
926570004388	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
926570004389	Ligand binding site; other site
926570004390	Putative Catalytic site; other site
926570004391	DXD motif; other site
926570004392	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
926570004393	PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate...; Region: PAF_acetylesterase_like; cd01820
926570004394	active site
926570004395	catalytic triad [active]
926570004396	oxyanion hole [active]
926570004397	specificity pocket; other site
926570004398	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
926570004399	DctM-like transporters; Region: DctM; pfam06808
926570004400	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
926570004401	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
926570004402	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
926570004403	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
926570004404	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
926570004405	PYR/PP interface [polypeptide binding]; other site
926570004406	dimer interface [polypeptide binding]; other site
926570004407	TPP binding site [chemical binding]; other site
926570004408	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926570004409	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
926570004410	TPP-binding site [chemical binding]; other site
926570004411	dimer interface [polypeptide binding]; other site
926570004412	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926570004413	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570004414	NAD(P) binding site [chemical binding]; other site
926570004415	active site
926570004416	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
926570004417	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570004418	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
926570004419	dimerization interface [polypeptide binding]; other site
926570004420	substrate binding pocket [chemical binding]; other site
926570004421	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570004422	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570004423	active site
926570004424	phosphorylation site [posttranslational modification]
926570004425	intermolecular recognition site; other site
926570004426	dimerization interface [polypeptide binding]; other site
926570004427	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570004428	DNA binding site [nucleotide binding]
926570004429	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
926570004430	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
926570004431	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
926570004432	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570004433	dimer interface [polypeptide binding]; other site
926570004434	phosphorylation site [posttranslational modification]
926570004435	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570004436	ATP binding site [chemical binding]; other site
926570004437	G-X-G motif; other site
926570004438	K+-transporting ATPase, c chain; Region: KdpC; cl00944
926570004439	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
926570004440	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926570004441	Soluble P-type ATPase [General function prediction only]; Region: COG4087
926570004442	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
926570004443	lysyl-tRNA synthetase; Reviewed; Region: lysK; PRK00750
926570004444	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
926570004445	active site
926570004446	nucleotide binding site [chemical binding]; other site
926570004447	HIGH motif; other site
926570004448	KMSKS motif; other site
926570004449	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
926570004450	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
926570004451	Int/Topo IB signature motif; other site
926570004452	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
926570004453	Putative transposase; Region: Y2_Tnp; pfam04986
926570004454	Peptide chain release factor RF-3 [Translation, ribosomal structure and biogenesis]; Region: PrfC; COG4108
926570004455	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
926570004456	G1 box; other site
926570004457	putative GEF interaction site [polypeptide binding]; other site
926570004458	GTP/Mg2+ binding site [chemical binding]; other site
926570004459	Switch I region; other site
926570004460	G2 box; other site
926570004461	G3 box; other site
926570004462	Switch II region; other site
926570004463	G4 box; other site
926570004464	G5 box; other site
926570004465	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
926570004466	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
926570004467	Class I histone deacetylase AcuC (Acetoin utilization protein)-like enzymes; Region: HDAC_AcuC_like; cd09994
926570004468	active site
926570004469	Zn binding site [ion binding]; other site
926570004470	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
926570004471	ETC complex I subunit conserved region; Region: ETC_C1_NDUFA4; pfam04800
926570004472	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
926570004473	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
926570004474	catalytic residue [active]
926570004475	Class I aldolases; Region: Aldolase_Class_I; cl17187
926570004476	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926570004477	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
926570004478	substrate binding site [chemical binding]; other site
926570004479	ATP binding site [chemical binding]; other site
926570004480	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
926570004481	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
926570004482	Walker A/P-loop; other site
926570004483	ATP binding site [chemical binding]; other site
926570004484	Q-loop/lid; other site
926570004485	ABC transporter signature motif; other site
926570004486	Walker B; other site
926570004487	D-loop; other site
926570004488	H-loop/switch region; other site
926570004489	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570004490	dimer interface [polypeptide binding]; other site
926570004491	conserved gate region; other site
926570004492	putative PBP binding loops; other site
926570004493	ABC-ATPase subunit interface; other site
926570004494	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926570004495	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926570004496	substrate binding pocket [chemical binding]; other site
926570004497	membrane-bound complex binding site; other site
926570004498	hinge residues; other site
926570004499	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
926570004500	PAS fold; Region: PAS; pfam00989
926570004501	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570004502	putative active site [active]
926570004503	heme pocket [chemical binding]; other site
926570004504	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570004505	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570004506	dimer interface [polypeptide binding]; other site
926570004507	putative CheW interface [polypeptide binding]; other site
926570004508	HPP family; Region: HPP; pfam04982
926570004509	Protein of unknown function (DUF983); Region: DUF983; cl02211
926570004510	Protein of unknown function (DUF983); Region: DUF983; pfam06170
926570004511	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
926570004512	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570004513	DNA-binding site [nucleotide binding]; DNA binding site
926570004514	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570004515	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570004516	homodimer interface [polypeptide binding]; other site
926570004517	catalytic residue [active]
926570004518	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570004519	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570004520	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
926570004521	putative effector binding pocket; other site
926570004522	dimerization interface [polypeptide binding]; other site
926570004523	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926570004524	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926570004525	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558
926570004526	SnoaL-like domain; Region: SnoaL_2; pfam12680
926570004527	Uncharacterized conserved protein [Function unknown]; Region: COG1359
926570004528	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
926570004529	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570004530	ligand binding site [chemical binding]; other site
926570004531	enoyl-CoA hydratase; Provisional; Region: PRK06688
926570004532	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570004533	substrate binding site [chemical binding]; other site
926570004534	oxyanion hole (OAH) forming residues; other site
926570004535	trimer interface [polypeptide binding]; other site
926570004536	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
926570004537	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570004538	Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929
926570004539	acyl-activating enzyme (AAE) consensus motif; other site
926570004540	acyl-activating enzyme (AAE) consensus motif; other site
926570004541	putative AMP binding site [chemical binding]; other site
926570004542	putative active site [active]
926570004543	putative CoA binding site [chemical binding]; other site
926570004544	4-hydroxybenzoyl-CoA reductase, gamma subunit; Region: 4hydroxCoAred; TIGR03193
926570004545	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570004546	catalytic loop [active]
926570004547	iron binding site [ion binding]; other site
926570004548	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926570004549	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
926570004550	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570004551	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570004552	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570004553	Carbon monoxide dehydrogenase subunit G (CoxG); Region: CoxG; cd05018
926570004554	putative hydrophobic ligand binding site [chemical binding]; other site
926570004555	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
926570004556	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
926570004557	active site clefts [active]
926570004558	zinc binding site [ion binding]; other site
926570004559	dimer interface [polypeptide binding]; other site
926570004560	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
926570004561	oligomerization interface [polypeptide binding]; other site
926570004562	active site
926570004563	metal binding site [ion binding]; metal-binding site
926570004564	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
926570004565	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
926570004566	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926570004567	RNA binding surface [nucleotide binding]; other site
926570004568	Hint domain; Region: Hint_2; pfam13403
926570004569	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
926570004570	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08314
926570004571	acyl-activating enzyme (AAE) consensus motif; other site
926570004572	putative AMP binding site [chemical binding]; other site
926570004573	putative active site [active]
926570004574	putative CoA binding site [chemical binding]; other site
926570004575	Putative cyclase; Region: Cyclase; pfam04199
926570004576	Putative cyclase; Region: Cyclase; cl00814
926570004577	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
926570004578	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
926570004579	heme-binding site [chemical binding]; other site
926570004580	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
926570004581	FAD binding pocket [chemical binding]; other site
926570004582	FAD binding motif [chemical binding]; other site
926570004583	phosphate binding motif [ion binding]; other site
926570004584	beta-alpha-beta structure motif; other site
926570004585	NAD binding pocket [chemical binding]; other site
926570004586	Heme binding  pocket [chemical binding]; other site
926570004587	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
926570004588	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
926570004589	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
926570004590	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
926570004591	rod shape-determining protein MreC; Provisional; Region: PRK13922
926570004592	rod shape-determining protein MreC; Region: MreC; pfam04085
926570004593	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
926570004594	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570004595	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
926570004596	dimerization interface [polypeptide binding]; other site
926570004597	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
926570004598	putative acyl-acceptor binding pocket; other site
926570004599	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
926570004600	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
926570004601	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
926570004602	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
926570004603	putative acyl-acceptor binding pocket; other site
926570004604	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
926570004605	tartrate dehydrogenase; Region: TTC; TIGR02089
926570004606	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
926570004607	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570004608	Coenzyme A binding pocket [chemical binding]; other site
926570004609	Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate,  or similar substrates; Region: Bacterial_IMPase_like_1; cd01641
926570004610	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926570004611	active site
926570004612	Cytochrome c2 [Energy production and conversion]; Region: COG3474
926570004613	Cytochrome c2 [Energy production and conversion]; Region: COG3474
926570004614	Cytochrome c; Region: Cytochrom_C; cl11414
926570004615	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
926570004616	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
926570004617	Ligand binding site; other site
926570004618	oligomer interface; other site
926570004619	prephenate dehydratase; Provisional; Region: PRK11899
926570004620	Prephenate dehydratase; Region: PDT; pfam00800
926570004621	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
926570004622	putative L-Phe binding site [chemical binding]; other site
926570004623	Hint domain; Region: Hint_2; pfam13403
926570004624	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
926570004625	RNA/DNA hybrid binding site [nucleotide binding]; other site
926570004626	active site
926570004627	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194
926570004628	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
926570004629	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
926570004630	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
926570004631	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
926570004632	active site
926570004633	HIGH motif; other site
926570004634	nucleotide binding site [chemical binding]; other site
926570004635	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
926570004636	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
926570004637	active site
926570004638	KMSKS motif; other site
926570004639	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
926570004640	tRNA binding surface [nucleotide binding]; other site
926570004641	anticodon binding site; other site
926570004642	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
926570004643	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
926570004644	lipoprotein signal peptidase; Provisional; Region: PRK14787
926570004645	Protein of unknown function (DUF3035); Region: DUF3035; pfam11233
926570004646	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
926570004647	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
926570004648	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
926570004649	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
926570004650	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570004651	ATP binding site [chemical binding]; other site
926570004652	Mg2+ binding site [ion binding]; other site
926570004653	G-X-G motif; other site
926570004654	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
926570004655	ATP binding site [chemical binding]; other site
926570004656	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
926570004657	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08217
926570004658	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570004659	NAD(P) binding site [chemical binding]; other site
926570004660	active site
926570004661	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
926570004662	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570004663	acyl-activating enzyme (AAE) consensus motif; other site
926570004664	AMP binding site [chemical binding]; other site
926570004665	active site
926570004666	CoA binding site [chemical binding]; other site
926570004667	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926570004668	3-hydroxyisobutyrate dehydrogenase; Region: HIBADH; TIGR01692
926570004669	3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617
926570004670	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570004671	substrate binding site [chemical binding]; other site
926570004672	oxyanion hole (OAH) forming residues; other site
926570004673	trimer interface [polypeptide binding]; other site
926570004674	2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766
926570004675	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570004676	Isobutyryl-CoA dehydrogenase; Region: IBD; cd01162
926570004677	substrate binding pocket [chemical binding]; other site
926570004678	FAD binding site [chemical binding]; other site
926570004679	catalytic base [active]
926570004680	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
926570004681	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
926570004682	tetramer interface [polypeptide binding]; other site
926570004683	active site
926570004684	Mg2+/Mn2+ binding site [ion binding]; other site
926570004685	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
926570004686	methylcitrate synthase; Provisional; Region: PRK12351
926570004687	oxalacetate binding site [chemical binding]; other site
926570004688	citrylCoA binding site [chemical binding]; other site
926570004689	coenzyme A binding site [chemical binding]; other site
926570004690	catalytic triad [active]
926570004691	Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079
926570004692	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187
926570004693	Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles; Region: ttLC_FACS_AlkK_like; cd12119
926570004694	dimer interface [polypeptide binding]; other site
926570004695	acyl-activating enzyme (AAE) consensus motif; other site
926570004696	putative active site [active]
926570004697	AMP binding site [chemical binding]; other site
926570004698	putative CoA binding site [chemical binding]; other site
926570004699	gluconate 5-dehydrogenase; Provisional; Region: PRK08213
926570004700	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570004701	NAD(P) binding site [chemical binding]; other site
926570004702	active site
926570004703	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
926570004704	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
926570004705	Amidase; Region: Amidase; cl11426
926570004706	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
926570004707	putative ligand binding site [chemical binding]; other site
926570004708	putative catalytic site [active]
926570004709	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570004710	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570004711	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926570004712	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
926570004713	active site
926570004714	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
926570004715	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
926570004716	NAD binding site [chemical binding]; other site
926570004717	substrate binding site [chemical binding]; other site
926570004718	homodimer interface [polypeptide binding]; other site
926570004719	active site
926570004720	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
926570004721	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
926570004722	substrate binding site; other site
926570004723	tetramer interface; other site
926570004724	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
926570004725	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
926570004726	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570004727	active site
926570004728	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926570004729	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570004730	active site
926570004731	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
926570004732	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
926570004733	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
926570004734	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
926570004735	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
926570004736	TPP-binding site [chemical binding]; other site
926570004737	dimer interface [polypeptide binding]; other site
926570004738	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
926570004739	PYR/PP interface [polypeptide binding]; other site
926570004740	dimer interface [polypeptide binding]; other site
926570004741	TPP binding site [chemical binding]; other site
926570004742	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926570004743	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
926570004744	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
926570004745	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
926570004746	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
926570004747	Phosphoglycerate kinase; Region: PGK; pfam00162
926570004748	substrate binding site [chemical binding]; other site
926570004749	hinge regions; other site
926570004750	ADP binding site [chemical binding]; other site
926570004751	catalytic site [active]
926570004752	protease TldD; Provisional; Region: tldD; PRK10735
926570004753	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
926570004754	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
926570004755	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
926570004756	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
926570004757	transcription termination factor Rho; Provisional; Region: rho; PRK09376
926570004758	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
926570004759	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
926570004760	RNA binding site [nucleotide binding]; other site
926570004761	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
926570004762	multimer interface [polypeptide binding]; other site
926570004763	Walker A motif; other site
926570004764	ATP binding site [chemical binding]; other site
926570004765	Walker B motif; other site
926570004766	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
926570004767	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
926570004768	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
926570004769	homotetramer interface [polypeptide binding]; other site
926570004770	ligand binding site [chemical binding]; other site
926570004771	catalytic site [active]
926570004772	NAD binding site [chemical binding]; other site
926570004773	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
926570004774	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
926570004775	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
926570004776	dimer interface [polypeptide binding]; other site
926570004777	putative functional site; other site
926570004778	putative MPT binding site; other site
926570004779	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
926570004780	trimer interface [polypeptide binding]; other site
926570004781	dimer interface [polypeptide binding]; other site
926570004782	putative active site [active]
926570004783	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
926570004784	active site
926570004785	ribulose/triose binding site [chemical binding]; other site
926570004786	phosphate binding site [ion binding]; other site
926570004787	substrate (anthranilate) binding pocket [chemical binding]; other site
926570004788	product (indole) binding pocket [chemical binding]; other site
926570004789	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
926570004790	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
926570004791	glutamine binding [chemical binding]; other site
926570004792	catalytic triad [active]
926570004793	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
926570004794	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
926570004795	anthranilate synthase component I; Provisional; Region: PRK13573
926570004796	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
926570004797	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
926570004798	SurA N-terminal domain; Region: SurA_N_3; cl07813
926570004799	periplasmic folding chaperone; Provisional; Region: PRK10788
926570004800	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
926570004801	triosephosphate isomerase; Provisional; Region: PRK14565
926570004802	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
926570004803	substrate binding site [chemical binding]; other site
926570004804	dimer interface [polypeptide binding]; other site
926570004805	catalytic triad [active]
926570004806	CTP synthetase; Validated; Region: pyrG; PRK05380
926570004807	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
926570004808	Catalytic site [active]
926570004809	active site
926570004810	UTP binding site [chemical binding]; other site
926570004811	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
926570004812	active site
926570004813	putative oxyanion hole; other site
926570004814	catalytic triad [active]
926570004815	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
926570004816	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
926570004817	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
926570004818	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
926570004819	FAD binding pocket [chemical binding]; other site
926570004820	FAD binding motif [chemical binding]; other site
926570004821	phosphate binding motif [ion binding]; other site
926570004822	beta-alpha-beta structure motif; other site
926570004823	NAD binding pocket [chemical binding]; other site
926570004824	malate synthase G; Provisional; Region: PRK02999
926570004825	active site
926570004826	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
926570004827	heme-binding site [chemical binding]; other site
926570004828	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570004829	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
926570004830	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
926570004831	YceI-like domain; Region: YceI; smart00867
926570004832	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
926570004833	choline dehydrogenase; Validated; Region: PRK02106
926570004834	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
926570004835	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
926570004836	Pseudomonas putida Aldehyde dehydrogenase AlkH-like; Region: ALDH_AlkH-like; cd07134
926570004837	NAD(P) binding site [chemical binding]; other site
926570004838	catalytic residues [active]
926570004839	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926570004840	active site 2 [active]
926570004841	active site 1 [active]
926570004842	Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059
926570004843	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570004844	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
926570004845	acyl-activating enzyme (AAE) consensus motif; other site
926570004846	putative AMP binding site [chemical binding]; other site
926570004847	putative active site [active]
926570004848	putative CoA binding site [chemical binding]; other site
926570004849	acetyl-CoA acetyltransferase; Provisional; Region: PRK09268
926570004850	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926570004851	dimer interface [polypeptide binding]; other site
926570004852	active site
926570004853	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926570004854	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926570004855	active site 1 [active]
926570004856	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08261
926570004857	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570004858	NAD(P) binding site [chemical binding]; other site
926570004859	active site
926570004860	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
926570004861	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570004862	active site
926570004863	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
926570004864	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
926570004865	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570004866	catalytic loop [active]
926570004867	iron binding site [ion binding]; other site
926570004868	The oxygenase reductase FAD/NADH binding domain acts as part of the multi-component bacterial oxygenases which oxidize hydrocarbons. Electron transfer is from NADH via FAD (in the oxygenase reductase) and an [2FE-2S] ferredoxin center (fused to the FAD...; Region: oxygenase_e_transfer_subunit; cd06213
926570004869	FAD binding pocket [chemical binding]; other site
926570004870	FAD binding motif [chemical binding]; other site
926570004871	phosphate binding motif [ion binding]; other site
926570004872	beta-alpha-beta structure motif; other site
926570004873	NAD binding pocket [chemical binding]; other site
926570004874	Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes...; Region: Alkane-hydroxylase; cd03512
926570004875	Fatty acid desaturase; Region: FA_desaturase; pfam00487
926570004876	Di-iron ligands [ion binding]; other site
926570004877	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
926570004878	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
926570004879	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
926570004880	phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338
926570004881	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570004882	DNA-binding site [nucleotide binding]; DNA binding site
926570004883	FCD domain; Region: FCD; pfam07729
926570004884	MmgE/PrpD family; Region: MmgE_PrpD; cl00912
926570004885	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570004886	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570004887	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570004888	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
926570004889	tartrate dehydrogenase; Region: TTC; TIGR02089
926570004890	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
926570004891	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
926570004892	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
926570004893	tetramer (dimer of dimers) interface [polypeptide binding]; other site
926570004894	active site
926570004895	dimer interface [polypeptide binding]; other site
926570004896	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
926570004897	AAA domain; Region: AAA_33; pfam13671
926570004898	ATP-binding site [chemical binding]; other site
926570004899	Gluconate-6-phosphate binding site [chemical binding]; other site
926570004900	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
926570004901	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
926570004902	putative active site [active]
926570004903	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570004904	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
926570004905	active site
926570004906	motif I; other site
926570004907	motif II; other site
926570004908	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
926570004909	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
926570004910	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
926570004911	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
926570004912	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
926570004913	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926570004914	bifunctional transaldolase/phosoglucose isomerase; Validated; Region: PRK09533
926570004915	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
926570004916	putative active site [active]
926570004917	catalytic residue [active]
926570004918	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
926570004919	active site
926570004920	dimer interface [polypeptide binding]; other site
926570004921	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
926570004922	GTP-binding protein LepA; Provisional; Region: PRK05433
926570004923	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
926570004924	G1 box; other site
926570004925	putative GEF interaction site [polypeptide binding]; other site
926570004926	GTP/Mg2+ binding site [chemical binding]; other site
926570004927	Switch I region; other site
926570004928	G2 box; other site
926570004929	G3 box; other site
926570004930	Switch II region; other site
926570004931	G4 box; other site
926570004932	G5 box; other site
926570004933	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
926570004934	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
926570004935	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
926570004936	RmuC family; Region: RmuC; pfam02646
926570004937	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
926570004938	Immunity protein Imm5; Region: Imm5; pfam14423
926570004939	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570004940	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570004941	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570004942	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570004943	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570004944	Predicted membrane protein [Function unknown]; Region: COG2259
926570004945	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570004946	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570004947	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
926570004948	putative effector binding pocket; other site
926570004949	dimerization interface [polypeptide binding]; other site
926570004950	potential frameshift: common BLAST hit: gi|222102404|ref|YP_002546545.1| transposase
926570004951	HTH-like domain; Region: HTH_21; pfam13276
926570004952	Integrase core domain; Region: rve; pfam00665
926570004953	putative transposase OrfB; Reviewed; Region: PHA02517
926570004954	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570004955	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570004956	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570004957	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570004958	potential frameshift: common BLAST hit: gi|148260291|ref|YP_001234418.1| methyl-accepting chemotaxis sensory transducer
926570004959	PAS domain; Region: PAS_9; pfam13426
926570004960	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570004961	putative active site [active]
926570004962	heme pocket [chemical binding]; other site
926570004963	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570004964	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570004965	dimer interface [polypeptide binding]; other site
926570004966	putative CheW interface [polypeptide binding]; other site
926570004967	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570004968	PAS domain; Region: PAS_9; pfam13426
926570004969	putative active site [active]
926570004970	heme pocket [chemical binding]; other site
926570004971	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
926570004972	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
926570004973	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
926570004974	CESA_like_2 is a member of the cellulose synthase superfamily; Region: CESA_like_2; cd06427
926570004975	DXD motif; other site
926570004976	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570004977	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570004978	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570004979	active site
926570004980	potential protein location (hypothetical protein ACMV_13410 [Acidiphilium multivorum AIU301]) that overlaps RNA (tRNA-E)
926570004981	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
926570004982	DHH family; Region: DHH; pfam01368
926570004983	DHHA1 domain; Region: DHHA1; pfam02272
926570004984	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
926570004985	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
926570004986	putative active site [active]
926570004987	homoserine dehydrogenase; Provisional; Region: PRK06349
926570004988	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
926570004989	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
926570004990	aminotransferase; Validated; Region: PRK09148
926570004991	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570004992	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570004993	homodimer interface [polypeptide binding]; other site
926570004994	catalytic residue [active]
926570004995	poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838
926570004996	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
926570004997	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926570004998	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570004999	O-Antigen ligase; Region: Wzy_C; pfam04932
926570005000	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
926570005001	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
926570005002	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
926570005003	P-loop, Walker A motif; other site
926570005004	Base recognition motif; other site
926570005005	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
926570005006	FOG: WD40 repeat [General function prediction only]; Region: COG2319
926570005007	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
926570005008	structural tetrad; other site
926570005009	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926570005010	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926570005011	active site
926570005012	catalytic tetrad [active]
926570005013	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
926570005014	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
926570005015	G1 box; other site
926570005016	putative GEF interaction site [polypeptide binding]; other site
926570005017	GTP/Mg2+ binding site [chemical binding]; other site
926570005018	Switch I region; other site
926570005019	G2 box; other site
926570005020	G3 box; other site
926570005021	Switch II region; other site
926570005022	G4 box; other site
926570005023	G5 box; other site
926570005024	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
926570005025	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
926570005026	muropeptide transporter; Reviewed; Region: ampG; PRK11902
926570005027	muropeptide transporter; Validated; Region: ampG; cl17669
926570005028	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
926570005029	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570005030	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570005031	ABC transporter; Region: ABC_tran_2; pfam12848
926570005032	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570005033	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
926570005034	active site
926570005035	multimer interface [polypeptide binding]; other site
926570005036	rod shape-determining protein MreB; Provisional; Region: PRK13927
926570005037	MreB and similar proteins; Region: MreB_like; cd10225
926570005038	nucleotide binding site [chemical binding]; other site
926570005039	Mg binding site [ion binding]; other site
926570005040	putative protofilament interaction site [polypeptide binding]; other site
926570005041	RodZ interaction site [polypeptide binding]; other site
926570005042	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926570005043	Ligand Binding Site [chemical binding]; other site
926570005044	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926570005045	MarR family; Region: MarR; pfam01047
926570005046	Pirin-related protein [General function prediction only]; Region: COG1741
926570005047	Pirin; Region: Pirin; pfam02678
926570005048	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
926570005049	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
926570005050	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926570005051	protein binding site [polypeptide binding]; other site
926570005052	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926570005053	protein binding site [polypeptide binding]; other site
926570005054	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
926570005055	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
926570005056	Active Sites [active]
926570005057	bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Provisional; Region: PRK05506
926570005058	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
926570005059	G1 box; other site
926570005060	putative GEF interaction site [polypeptide binding]; other site
926570005061	GTP/Mg2+ binding site [chemical binding]; other site
926570005062	Switch I region; other site
926570005063	G2 box; other site
926570005064	CysD dimerization site [polypeptide binding]; other site
926570005065	G3 box; other site
926570005066	Switch II region; other site
926570005067	G4 box; other site
926570005068	G5 box; other site
926570005069	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
926570005070	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
926570005071	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
926570005072	ligand-binding site [chemical binding]; other site
926570005073	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
926570005074	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
926570005075	Tetramer interface [polypeptide binding]; other site
926570005076	active site
926570005077	FMN-binding site [chemical binding]; other site
926570005078	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926570005079	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_10; cd06345
926570005080	putative ligand binding site [chemical binding]; other site
926570005081	Domain of unknown function (DUF336); Region: DUF336; cl01249
926570005082	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
926570005083	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926570005084	protein binding site [polypeptide binding]; other site
926570005085	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
926570005086	protein binding site [polypeptide binding]; other site
926570005087	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
926570005088	active site
926570005089	HIGH motif; other site
926570005090	nucleotide binding site [chemical binding]; other site
926570005091	putative hydrolase; Provisional; Region: PRK11460
926570005092	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
926570005093	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
926570005094	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
926570005095	active site
926570005096	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
926570005097	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
926570005098	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570005099	catalytic residue [active]
926570005100	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
926570005101	substrate binding site [chemical binding]; other site
926570005102	active site
926570005103	catalytic residues [active]
926570005104	heterodimer interface [polypeptide binding]; other site
926570005105	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
926570005106	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
926570005107	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926570005108	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
926570005109	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
926570005110	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
926570005111	generic binding surface II; other site
926570005112	generic binding surface I; other site
926570005113	Anti-sigma-K factor rskA; Region: RskA; pfam10099
926570005114	RNA polymerase sigma factor; Provisional; Region: PRK12537
926570005115	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926570005116	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926570005117	DNA binding residues [nucleotide binding]
926570005118	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
926570005119	metal binding site 2 [ion binding]; metal-binding site
926570005120	putative DNA binding helix; other site
926570005121	metal binding site 1 [ion binding]; metal-binding site
926570005122	dimer interface [polypeptide binding]; other site
926570005123	structural Zn2+ binding site [ion binding]; other site
926570005124	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496
926570005125	Stringent starvation protein B; Region: SspB; pfam04386
926570005126	fumarate hydratase; Provisional; Region: PRK15389
926570005127	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
926570005128	Fumarase C-terminus; Region: Fumerase_C; pfam05683
926570005129	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
926570005130	dimer interface [polypeptide binding]; other site
926570005131	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926570005132	metal binding site [ion binding]; metal-binding site
926570005133	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
926570005134	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
926570005135	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
926570005136	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
926570005137	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
926570005138	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
926570005139	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
926570005140	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
926570005141	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
926570005142	LrgB-like family; Region: LrgB; cl00596
926570005143	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570005144	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570005145	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
926570005146	putative effector binding pocket; other site
926570005147	dimerization interface [polypeptide binding]; other site
926570005148	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
926570005149	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570005150	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
926570005151	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
926570005152	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570005153	S-adenosylmethionine binding site [chemical binding]; other site
926570005154	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570005155	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
926570005156	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570005157	Methyltransferase domain; Region: Methyltransf_11; pfam08241
926570005158	Rhamnan synthesis protein F; Region: RgpF; pfam05045
926570005159	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
926570005160	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
926570005161	putative acyl-acceptor binding pocket; other site
926570005162	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
926570005163	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
926570005164	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570005165	FeS/SAM binding site; other site
926570005166	TRAM domain; Region: TRAM; pfam01938
926570005167	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
926570005168	PhoH-like protein; Region: PhoH; pfam02562
926570005169	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
926570005170	FOG: CBS domain [General function prediction only]; Region: COG0517
926570005171	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
926570005172	Transporter associated domain; Region: CorC_HlyC; smart01091
926570005173	Protein of unknown function (DUF1330); Region: DUF1330; cl02288
926570005174	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926570005175	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926570005176	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570005177	Walker A/P-loop; other site
926570005178	ATP binding site [chemical binding]; other site
926570005179	Q-loop/lid; other site
926570005180	ABC transporter signature motif; other site
926570005181	Walker B; other site
926570005182	D-loop; other site
926570005183	H-loop/switch region; other site
926570005184	This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802
926570005185	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570005186	putative ADP-binding pocket [chemical binding]; other site
926570005187	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570005188	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570005189	Walker A/P-loop; other site
926570005190	ATP binding site [chemical binding]; other site
926570005191	Q-loop/lid; other site
926570005192	ABC transporter signature motif; other site
926570005193	Walker B; other site
926570005194	D-loop; other site
926570005195	H-loop/switch region; other site
926570005196	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570005197	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570005198	TM-ABC transporter signature motif; other site
926570005199	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_2; cd06310
926570005200	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570005201	putative ligand binding site [chemical binding]; other site
926570005202	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
926570005203	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
926570005204	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570005205	AlkA N-terminal domain; Region: AlkA_N; pfam06029
926570005206	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
926570005207	minor groove reading motif; other site
926570005208	helix-hairpin-helix signature motif; other site
926570005209	active site
926570005210	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
926570005211	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
926570005212	DNA binding site [nucleotide binding]
926570005213	active site
926570005214	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
926570005215	homodimer interface [polypeptide binding]; other site
926570005216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570005217	catalytic residue [active]
926570005218	Tic20-like protein; Region: Tic20; pfam09685
926570005219	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
926570005220	GAF domain; Region: GAF; pfam01590
926570005221	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570005222	Walker A motif; other site
926570005223	ATP binding site [chemical binding]; other site
926570005224	Walker B motif; other site
926570005225	arginine finger; other site
926570005226	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570005227	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
926570005228	chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; Region: chaperonin_like; cl02777
926570005229	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
926570005230	active site
926570005231	MmoB/DmpM family; Region: MmoB_DmpM; pfam02406
926570005232	Aromatic and Alkene Monooxygenase Hydroxylase, subunit B, ferritin-like diiron-binding domain; Region: AAMH_B; cd01058
926570005233	dimerization interface [polypeptide binding]; other site
926570005234	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
926570005235	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570005236	catalytic loop [active]
926570005237	iron binding site [ion binding]; other site
926570005238	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
926570005239	FAD binding pocket [chemical binding]; other site
926570005240	conserved FAD binding motif [chemical binding]; other site
926570005241	phosphate binding motif [ion binding]; other site
926570005242	beta-alpha-beta structure motif; other site
926570005243	NAD binding pocket [chemical binding]; other site
926570005244	Aromatic and Alkene Monooxygenase Hydroxylase, subunit A, ferritin-like diiron-binding domain; Region: AAMH_A; cd01057
926570005245	dimerization interface [polypeptide binding]; other site
926570005246	putative path to active site cavity [active]
926570005247	diiron center [ion binding]; other site
926570005248	Ribbon-helix-helix domain; Region: RHH_4; pfam13467
926570005249	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
926570005250	dimer interface [polypeptide binding]; other site
926570005251	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926570005252	active site
926570005253	metal binding site [ion binding]; metal-binding site
926570005254	glutathione binding site [chemical binding]; other site
926570005255	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
926570005256	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926570005257	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926570005258	catalytic residues [active]
926570005259	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
926570005260	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570005261	dimerization interface [polypeptide binding]; other site
926570005262	putative DNA binding site [nucleotide binding]; other site
926570005263	putative Zn2+ binding site [ion binding]; other site
926570005264	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926570005265	active site residue [active]
926570005266	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
926570005267	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926570005268	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570005269	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
926570005270	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570005271	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570005272	non-specific DNA binding site [nucleotide binding]; other site
926570005273	salt bridge; other site
926570005274	sequence-specific DNA binding site [nucleotide binding]; other site
926570005275	hydrogenase 4 subunit B; Validated; Region: PRK06521
926570005276	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570005277	NADH dehydrogenase; Region: NADHdh; cl00469
926570005278	Hydrogenase 4 membrane component (E) [Energy production and conversion]; Region: HyfE; cl17899
926570005279	hydrogenase 4 subunit F; Validated; Region: PRK06458
926570005280	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570005281	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
926570005282	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
926570005283	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
926570005284	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194
926570005285	Ferritin-like domain; Region: Ferritin; pfam00210
926570005286	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
926570005287	dinuclear metal binding motif [ion binding]; other site
926570005288	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
926570005289	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
926570005290	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
926570005291	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
926570005292	active site
926570005293	HIGH motif; other site
926570005294	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
926570005295	KMSKS motif; other site
926570005296	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
926570005297	tRNA binding surface [nucleotide binding]; other site
926570005298	anticodon binding site; other site
926570005299	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
926570005300	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
926570005301	acetylornithine deacetylase; Provisional; Region: PRK06837
926570005302	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like2; cd03895
926570005303	metal binding site [ion binding]; metal-binding site
926570005304	dimer interface [polypeptide binding]; other site
926570005305	amidase; Provisional; Region: PRK07487
926570005306	Amidase; Region: Amidase; cl11426
926570005307	Short C-terminal domain; Region: SHOCT; pfam09851
926570005308	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
926570005309	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570005310	Walker A motif; other site
926570005311	ATP binding site [chemical binding]; other site
926570005312	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
926570005313	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
926570005314	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
926570005315	active site
926570005316	HslU subunit interaction site [polypeptide binding]; other site
926570005317	Phosphate-starvation-inducible E; Region: PsiE; pfam06146
926570005318	benzoate transport; Region: 2A0115; TIGR00895
926570005319	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570005320	putative substrate translocation pore; other site
926570005321	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570005322	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
926570005323	4-fold oligomerization interface [polypeptide binding]; other site
926570005324	putative active site pocket [active]
926570005325	metal binding residues [ion binding]; metal-binding site
926570005326	3-fold/trimer interface [polypeptide binding]; other site
926570005327	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146
926570005328	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
926570005329	putative active site [active]
926570005330	oxyanion strand; other site
926570005331	catalytic triad [active]
926570005332	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570005333	Coenzyme A binding pocket [chemical binding]; other site
926570005334	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
926570005335	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
926570005336	catalytic residues [active]
926570005337	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
926570005338	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
926570005339	substrate binding site [chemical binding]; other site
926570005340	glutamase interaction surface [polypeptide binding]; other site
926570005341	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
926570005342	metal binding site [ion binding]; metal-binding site
926570005343	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
926570005344	nucleotide binding site/active site [active]
926570005345	HIT family signature motif; other site
926570005346	catalytic residue [active]
926570005347	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
926570005348	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570005349	active site
926570005350	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
926570005351	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
926570005352	putative active site [active]
926570005353	Hydroxyacid-oxoacid transhydrogenase (HOT) involved in gamma-hydroxybutyrate metabolism; Region: HOT; cd08190
926570005354	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
926570005355	putative active site [active]
926570005356	metal binding site [ion binding]; metal-binding site
926570005357	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
926570005358	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926570005359	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005360	NAD(P) binding site [chemical binding]; other site
926570005361	active site
926570005362	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
926570005363	short chain dehydrogenase; Provisional; Region: PRK06125
926570005364	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005365	NAD(P) binding site [chemical binding]; other site
926570005366	active site
926570005367	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
926570005368	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005369	NAD(P) binding site [chemical binding]; other site
926570005370	active site
926570005371	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07008
926570005372	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570005373	acyl-activating enzyme (AAE) consensus motif; other site
926570005374	AMP binding site [chemical binding]; other site
926570005375	active site
926570005376	CoA binding site [chemical binding]; other site
926570005377	Bacterial NAD-glutamate dehydrogenase; Region: Bac_GDH; pfam05088
926570005378	FtsH Extracellular; Region: FtsH_ext; pfam06480
926570005379	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
926570005380	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570005381	Walker A motif; other site
926570005382	ATP binding site [chemical binding]; other site
926570005383	Walker B motif; other site
926570005384	arginine finger; other site
926570005385	Peptidase family M41; Region: Peptidase_M41; pfam01434
926570005386	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
926570005387	putative catalytic site [active]
926570005388	putative metal binding site [ion binding]; other site
926570005389	putative phosphate binding site [ion binding]; other site
926570005390	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
926570005391	Putative catalytic domain, repeat 1, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar2_1; cd09157
926570005392	putative active site [active]
926570005393	catalytic site [active]
926570005394	Putative catalytic domain, repeat 2, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar2_2; cd09163
926570005395	putative active site [active]
926570005396	catalytic site [active]
926570005397	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926570005398	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
926570005399	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
926570005400	substrate binding pocket [chemical binding]; other site
926570005401	chain length determination region; other site
926570005402	substrate-Mg2+ binding site; other site
926570005403	catalytic residues [active]
926570005404	aspartate-rich region 1; other site
926570005405	active site lid residues [active]
926570005406	aspartate-rich region 2; other site
926570005407	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
926570005408	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
926570005409	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570005410	Protein required for attachment to host cells; Region: Host_attach; pfam10116
926570005411	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
926570005412	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
926570005413	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
926570005414	DNA polymerase III subunit beta; Validated; Region: PRK05643
926570005415	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
926570005416	putative DNA binding surface [nucleotide binding]; other site
926570005417	dimer interface [polypeptide binding]; other site
926570005418	beta-clamp/clamp loader binding surface; other site
926570005419	beta-clamp/translesion DNA polymerase binding surface; other site
926570005420	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
926570005421	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570005422	dimer interface [polypeptide binding]; other site
926570005423	putative PBP binding loops; other site
926570005424	ABC-ATPase subunit interface; other site
926570005425	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570005426	dimer interface [polypeptide binding]; other site
926570005427	conserved gate region; other site
926570005428	putative PBP binding loops; other site
926570005429	ABC-ATPase subunit interface; other site
926570005430	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926570005431	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926570005432	Walker A/P-loop; other site
926570005433	ATP binding site [chemical binding]; other site
926570005434	Q-loop/lid; other site
926570005435	ABC transporter signature motif; other site
926570005436	Walker B; other site
926570005437	D-loop; other site
926570005438	H-loop/switch region; other site
926570005439	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
926570005440	fumarate hydratase; Reviewed; Region: fumC; PRK00485
926570005441	Class II fumarases; Region: Fumarase_classII; cd01362
926570005442	active site
926570005443	tetramer interface [polypeptide binding]; other site
926570005444	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570005445	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570005446	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570005447	dimerization interface [polypeptide binding]; other site
926570005448	Predicted membrane protein [Function unknown]; Region: COG2259
926570005449	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
926570005450	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
926570005451	putative active site [active]
926570005452	metal binding site [ion binding]; metal-binding site
926570005453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570005454	Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591
926570005455	Na binding site [ion binding]; other site
926570005456	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
926570005457	Guanylate kinase; Region: Guanylate_kin; pfam00625
926570005458	catalytic site [active]
926570005459	G-X2-G-X-G-K; other site
926570005460	hypothetical protein; Provisional; Region: PRK11820
926570005461	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
926570005462	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
926570005463	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
926570005464	DNA methylase; Region: N6_N4_Mtase; pfam01555
926570005465	enoyl-CoA hydratase; Provisional; Region: PRK05862
926570005466	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570005467	substrate binding site [chemical binding]; other site
926570005468	oxyanion hole (OAH) forming residues; other site
926570005469	trimer interface [polypeptide binding]; other site
926570005470	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
926570005471	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570005472	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
926570005473	double-strand break repair protein AddB, alphaproteobacterial type; Region: addB_alphas; TIGR02786
926570005474	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
926570005475	double-strand break repair helicase AddA, alphaproteobacterial type; Region: addA_alphas; TIGR02784
926570005476	Family description; Region: UvrD_C_2; pfam13538
926570005477	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
926570005478	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926570005479	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926570005480	catalytic residues [active]
926570005481	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
926570005482	benzoate transport; Region: 2A0115; TIGR00895
926570005483	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570005484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570005485	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926570005486	active site
926570005487	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926570005488	catalytic tetrad [active]
926570005489	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
926570005490	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
926570005491	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
926570005492	FAD binding domain; Region: FAD_binding_4; pfam01565
926570005493	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
926570005494	putative active site [active]
926570005495	metal binding site [ion binding]; metal-binding site
926570005496	homodimer binding site [polypeptide binding]; other site
926570005497	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
926570005498	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
926570005499	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
926570005500	bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional; Region: PRK14021
926570005501	ADP binding site [chemical binding]; other site
926570005502	magnesium binding site [ion binding]; other site
926570005503	putative shikimate binding site; other site
926570005504	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
926570005505	active site
926570005506	dimer interface [polypeptide binding]; other site
926570005507	metal binding site [ion binding]; metal-binding site
926570005508	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
926570005509	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570005510	active site
926570005511	DNA binding site [nucleotide binding]
926570005512	Int/Topo IB signature motif; other site
926570005513	septum site-determining protein MinD; Region: minD_bact; TIGR01968
926570005514	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926570005515	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
926570005516	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926570005517	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
926570005518	FHIPEP family; Region: FHIPEP; pfam00771
926570005519	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
926570005520	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570005521	Walker A motif; other site
926570005522	ATP binding site [chemical binding]; other site
926570005523	Walker B motif; other site
926570005524	arginine finger; other site
926570005525	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570005526	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
926570005527	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
926570005528	FliG C-terminal domain; Region: FliG_C; pfam01706
926570005529	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
926570005530	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
926570005531	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
926570005532	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
926570005533	nucleoside/Zn binding site; other site
926570005534	dimer interface [polypeptide binding]; other site
926570005535	catalytic motif [active]
926570005536	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
926570005537	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
926570005538	catalytic triad [active]
926570005539	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
926570005540	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926570005541	RNA binding surface [nucleotide binding]; other site
926570005542	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
926570005543	active site
926570005544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926570005545	S-adenosylmethionine binding site [chemical binding]; other site
926570005546	Methyltransferase domain; Region: Methyltransf_24; pfam13578
926570005547	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
926570005548	ABC1 family; Region: ABC1; cl17513
926570005549	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
926570005550	active site
926570005551	ATP binding site [chemical binding]; other site
926570005552	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
926570005553	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
926570005554	active site
926570005555	Zn binding site [ion binding]; other site
926570005556	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
926570005557	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
926570005558	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
926570005559	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
926570005560	2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428
926570005561	Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; Region: HAD-SF-IA-v2; TIGR01493
926570005562	putative mechanosensitive channel protein; Provisional; Region: PRK11465
926570005563	Mechanosensitive ion channel; Region: MS_channel; pfam00924
926570005564	Biofilm formation and stress response factor; Region: BsmA; pfam10014
926570005565	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
926570005566	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
926570005567	dimer interface [polypeptide binding]; other site
926570005568	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570005569	catalytic residue [active]
926570005570	Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522
926570005571	active site residue [active]
926570005572	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570005573	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
926570005574	active site
926570005575	hypothetical protein; Reviewed; Region: PRK00024
926570005576	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
926570005577	MPN+ (JAMM) motif; other site
926570005578	Zinc-binding site [ion binding]; other site
926570005579	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570005580	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570005581	S-adenosylmethionine binding site [chemical binding]; other site
926570005582	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
926570005583	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570005584	active site
926570005585	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
926570005586	GSH binding site [chemical binding]; other site
926570005587	catalytic residues [active]
926570005588	Protein of unknown function (DUF1178); Region: DUF1178; pfam06676
926570005589	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
926570005590	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
926570005591	trimer interface [polypeptide binding]; other site
926570005592	putative metal binding site [ion binding]; other site
926570005593	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570005594	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570005595	non-specific DNA binding site [nucleotide binding]; other site
926570005596	salt bridge; other site
926570005597	sequence-specific DNA binding site [nucleotide binding]; other site
926570005598	Predicted transcriptional regulator [General function prediction only]; Region: COG3800
926570005599	Domain of unknown function (DUF955); Region: DUF955; pfam06114
926570005600	Predicted transcriptional regulator (DUF2083); Region: DUF2083; pfam09856
926570005601	isocitrate lyase; Provisional; Region: PRK15063
926570005602	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
926570005603	tetramer interface [polypeptide binding]; other site
926570005604	active site
926570005605	Mg2+/Mn2+ binding site [ion binding]; other site
926570005606	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
926570005607	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
926570005608	minor groove reading motif; other site
926570005609	helix-hairpin-helix signature motif; other site
926570005610	substrate binding pocket [chemical binding]; other site
926570005611	active site
926570005612	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
926570005613	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
926570005614	DNA binding and oxoG recognition site [nucleotide binding]
926570005615	Protein of unknown function (DUF721); Region: DUF721; pfam05258
926570005616	DNA polymerase I; Provisional; Region: PRK05755
926570005617	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
926570005618	active site
926570005619	putative 5' ssDNA interaction site; other site
926570005620	metal binding site 3; metal-binding site
926570005621	metal binding site 1 [ion binding]; metal-binding site
926570005622	metal binding site 2 [ion binding]; metal-binding site
926570005623	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
926570005624	putative DNA binding site [nucleotide binding]; other site
926570005625	putative metal binding site [ion binding]; other site
926570005626	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
926570005627	active site
926570005628	catalytic site [active]
926570005629	substrate binding site [chemical binding]; other site
926570005630	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
926570005631	active site
926570005632	DNA binding site [nucleotide binding]
926570005633	catalytic site [active]
926570005634	Zinc-finger domain; Region: zf-CHCC; pfam10276
926570005635	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
926570005636	trimer interface [polypeptide binding]; other site
926570005637	active site
926570005638	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
926570005639	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
926570005640	hinge; other site
926570005641	active site
926570005642	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
926570005643	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570005644	S-adenosylmethionine binding site [chemical binding]; other site
926570005645	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
926570005646	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
926570005647	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
926570005648	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
926570005649	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
926570005650	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
926570005651	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
926570005652	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926570005653	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926570005654	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
926570005655	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
926570005656	carboxyltransferase (CT) interaction site; other site
926570005657	biotinylation site [posttranslational modification]; other site
926570005658	enoyl-CoA hydratase; Provisional; Region: PRK05995
926570005659	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570005660	substrate binding site [chemical binding]; other site
926570005661	oxyanion hole (OAH) forming residues; other site
926570005662	trimer interface [polypeptide binding]; other site
926570005663	3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820
926570005664	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
926570005665	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
926570005666	Uncharacterized protein conserved in bacteria (DUF2320); Region: DUF2320; pfam10082
926570005667	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570005668	active site
926570005669	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
926570005670	Acyltransferase family; Region: Acyl_transf_3; pfam01757
926570005671	Chain length determinant protein; Region: Wzz; cl15801
926570005672	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
926570005673	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
926570005674	SLBB domain; Region: SLBB; pfam10531
926570005675	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
926570005676	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
926570005677	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
926570005678	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005679	NAD(P) binding site [chemical binding]; other site
926570005680	active site
926570005681	acyl carrier protein; Provisional; Region: acpP; PRK00982
926570005682	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
926570005683	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
926570005684	dimer interface [polypeptide binding]; other site
926570005685	active site
926570005686	YceG-like family; Region: YceG; pfam02618
926570005687	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
926570005688	dimerization interface [polypeptide binding]; other site
926570005689	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570005690	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570005691	I-site; other site
926570005692	active site
926570005693	metal binding site [ion binding]; metal-binding site
926570005694	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
926570005695	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
926570005696	trimer interface [polypeptide binding]; other site
926570005697	active site
926570005698	substrate binding site [chemical binding]; other site
926570005699	CoA binding site [chemical binding]; other site
926570005700	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
926570005701	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
926570005702	metal binding site [ion binding]; metal-binding site
926570005703	dimer interface [polypeptide binding]; other site
926570005704	Predicted methyltransferases [General function prediction only]; Region: COG0313
926570005705	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
926570005706	putative SAM binding site [chemical binding]; other site
926570005707	putative homodimer interface [polypeptide binding]; other site
926570005708	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926570005709	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
926570005710	putative ligand binding site [chemical binding]; other site
926570005711	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926570005712	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570005713	dimer interface [polypeptide binding]; other site
926570005714	phosphorylation site [posttranslational modification]
926570005715	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570005716	ATP binding site [chemical binding]; other site
926570005717	Mg2+ binding site [ion binding]; other site
926570005718	G-X-G motif; other site
926570005719	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
926570005720	Cation efflux family; Region: Cation_efflux; pfam01545
926570005721	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
926570005722	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
926570005723	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005724	NAD(P) binding site [chemical binding]; other site
926570005725	active site
926570005726	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
926570005727	quinolinate synthetase; Provisional; Region: PRK09375
926570005728	L-aspartate oxidase; Provisional; Region: PRK06175
926570005729	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
926570005730	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK06106
926570005731	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
926570005732	dimerization interface [polypeptide binding]; other site
926570005733	active site
926570005734	Protein of unknown function (DUF3429); Region: DUF3429; pfam11911
926570005735	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Region: CinA; COG1058
926570005736	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
926570005737	putative MPT binding site; other site
926570005738	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926570005739	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926570005740	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
926570005741	active site
926570005742	8-oxo-dGMP binding site [chemical binding]; other site
926570005743	nudix motif; other site
926570005744	metal binding site [ion binding]; metal-binding site
926570005745	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
926570005746	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
926570005747	putative catalytic cysteine [active]
926570005748	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
926570005749	active site
926570005750	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
926570005751	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
926570005752	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
926570005753	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570005754	heme pocket [chemical binding]; other site
926570005755	putative active site [active]
926570005756	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570005757	putative active site [active]
926570005758	heme pocket [chemical binding]; other site
926570005759	PAS domain S-box; Region: sensory_box; TIGR00229
926570005760	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570005761	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570005762	metal binding site [ion binding]; metal-binding site
926570005763	active site
926570005764	I-site; other site
926570005765	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570005766	PAS fold; Region: PAS_4; pfam08448
926570005767	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570005768	putative active site [active]
926570005769	heme pocket [chemical binding]; other site
926570005770	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570005771	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570005772	metal binding site [ion binding]; metal-binding site
926570005773	active site
926570005774	I-site; other site
926570005775	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570005776	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570005777	active site
926570005778	Transcriptional regulators [Transcription]; Region: GntR; COG1802
926570005779	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570005780	DNA-binding site [nucleotide binding]; DNA binding site
926570005781	FCD domain; Region: FCD; pfam07729
926570005782	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
926570005783	Predicted homoserine dehydrogenase [Amino acid transport and metabolism]; Region: COG4091
926570005784	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570005785	SAF domain of putative dehydrogenases or oxidoreductases; Region: SAF_DH_OX_like; cd11616
926570005786	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
926570005787	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570005788	FeS/SAM binding site; other site
926570005789	HemN C-terminal domain; Region: HemN_C; pfam06969
926570005790	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570005791	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570005792	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570005793	DinB family; Region: DinB; cl17821
926570005794	DinB superfamily; Region: DinB_2; pfam12867
926570005795	Cytochrome c [Energy production and conversion]; Region: COG3258
926570005796	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
926570005797	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005798	C factor cell-cell signaling protein; Provisional; Region: PRK09009
926570005799	NAD(P) binding site [chemical binding]; other site
926570005800	active site
926570005801	Cytochrome c; Region: Cytochrom_C; pfam00034
926570005802	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
926570005803	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926570005804	Trp docking motif [polypeptide binding]; other site
926570005805	active site
926570005806	Acyltransferase family; Region: Acyl_transf_3; pfam01757
926570005807	Integrase core domain; Region: rve; pfam00665
926570005808	transposase; Validated; Region: PRK08181
926570005809	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570005810	Walker A motif; other site
926570005811	ATP binding site [chemical binding]; other site
926570005812	Walker B motif; other site
926570005813	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
926570005814	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570005815	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570005816	active site
926570005817	Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806
926570005818	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926570005819	gluconate 5-dehydrogenase; Provisional; Region: PRK08213
926570005820	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005821	NAD(P) binding site [chemical binding]; other site
926570005822	active site
926570005823	acetyl-CoA acetyltransferase; Provisional; Region: PRK07108
926570005824	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926570005825	dimer interface [polypeptide binding]; other site
926570005826	active site
926570005827	NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.  Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450
926570005828	putative active site [active]
926570005829	putative catalytic site [active]
926570005830	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926570005831	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926570005832	active site
926570005833	catalytic tetrad [active]
926570005834	HerA helicase [Replication, recombination, and repair]; Region: COG0433
926570005835	transcriptional activator FtrB; Provisional; Region: ftrB; PRK09392
926570005836	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
926570005837	ligand binding site [chemical binding]; other site
926570005838	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
926570005839	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
926570005840	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
926570005841	[4Fe-4S] binding site [ion binding]; other site
926570005842	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926570005843	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926570005844	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926570005845	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
926570005846	molybdopterin cofactor binding site; other site
926570005847	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
926570005848	4Fe-4S binding domain; Region: Fer4; cl02805
926570005849	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
926570005850	Nitrate reductase gamma subunit; Region: Nitrate_red_gam; pfam02665
926570005851	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
926570005852	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
926570005853	MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase, which catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The family also includes the C-terminal domain in carbamoyl phosphate...; Region: MGS-like; cl00245
926570005854	MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase, which catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The family also includes the C-terminal domain in carbamoyl phosphate...; Region: MGS-like; cl00245
926570005855	substrate binding site [chemical binding]; other site
926570005856	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570005857	PAS domain; Region: PAS_9; pfam13426
926570005858	putative active site [active]
926570005859	heme pocket [chemical binding]; other site
926570005860	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570005861	PAS domain; Region: PAS_9; pfam13426
926570005862	putative active site [active]
926570005863	heme pocket [chemical binding]; other site
926570005864	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570005865	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570005866	dimer interface [polypeptide binding]; other site
926570005867	putative CheW interface [polypeptide binding]; other site
926570005868	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926570005869	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926570005870	DNA binding site [nucleotide binding]
926570005871	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
926570005872	putative dimerization interface [polypeptide binding]; other site
926570005873	putative ligand binding site [chemical binding]; other site
926570005874	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926570005875	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
926570005876	putative NAD(P) binding site [chemical binding]; other site
926570005877	catalytic Zn binding site [ion binding]; other site
926570005878	gluconate 5-dehydrogenase; Provisional; Region: PRK07523
926570005879	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570005880	NAD(P) binding site [chemical binding]; other site
926570005881	active site
926570005882	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
926570005883	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570005884	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570005885	Walker A/P-loop; other site
926570005886	ATP binding site [chemical binding]; other site
926570005887	Q-loop/lid; other site
926570005888	ABC transporter signature motif; other site
926570005889	Walker B; other site
926570005890	D-loop; other site
926570005891	H-loop/switch region; other site
926570005892	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570005893	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570005894	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570005895	TM-ABC transporter signature motif; other site
926570005896	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_6; cd06315
926570005897	putative ligand binding site [chemical binding]; other site
926570005898	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570005899	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
926570005900	phosphate:H+ symporter; Region: 2A0109; TIGR00887
926570005901	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570005902	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
926570005903	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
926570005904	active site
926570005905	metal binding site [ion binding]; metal-binding site
926570005906	hexamer interface [polypeptide binding]; other site
926570005907	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570005908	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570005909	Walker A/P-loop; other site
926570005910	ATP binding site [chemical binding]; other site
926570005911	Q-loop/lid; other site
926570005912	ABC transporter signature motif; other site
926570005913	Walker B; other site
926570005914	D-loop; other site
926570005915	H-loop/switch region; other site
926570005916	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926570005917	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570005918	ligand binding site [chemical binding]; other site
926570005919	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570005920	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570005921	TM-ABC transporter signature motif; other site
926570005922	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570005923	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570005924	metal binding site [ion binding]; metal-binding site
926570005925	active site
926570005926	I-site; other site
926570005927	molybdenum cofactor biosynthesis protein A; Provisional; Region: PRK13361
926570005928	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570005929	FeS/SAM binding site; other site
926570005930	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
926570005931	Protein of unknown function (DUF1013); Region: DUF1013; pfam06242
926570005932	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
926570005933	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
926570005934	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
926570005935	ATP-grasp domain; Region: ATP-grasp; pfam02222
926570005936	DNA ligase, ATP-dependent, PP_1105 family; Region: DNA_lig_bact; TIGR04120
926570005937	Adenylation domain of putative bacterial ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_Bac1; cd07897
926570005938	active site
926570005939	DNA binding site [nucleotide binding]
926570005940	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of archaeal and bacterial ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_Arch_LigB; cd07972
926570005941	DNA binding site [nucleotide binding]
926570005942	putative exonuclease, DNA ligase-associated; Region: Xnuc_lig_assoc; TIGR04122
926570005943	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
926570005944	DEXH box helicase, DNA ligase-associated; Region: DEXH_lig_assoc; TIGR04121
926570005945	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570005946	ATP binding site [chemical binding]; other site
926570005947	putative Mg++ binding site [ion binding]; other site
926570005948	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570005949	nucleotide binding region [chemical binding]; other site
926570005950	ATP-binding site [chemical binding]; other site
926570005951	DEAD/H associated; Region: DEAD_assoc; pfam08494
926570005952	metallophosphoesterase, DNA ligase-associated; Region: P_estr_lig_assc; TIGR04123
926570005953	active site
926570005954	metal binding site [ion binding]; metal-binding site
926570005955	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
926570005956	DNA photolyase; Region: DNA_photolyase; pfam00875
926570005957	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
926570005958	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926570005959	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926570005960	Protein of unknown function (DUF1365); Region: DUF1365; pfam07103
926570005961	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
926570005962	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570005963	S-adenosylmethionine binding site [chemical binding]; other site
926570005964	MFS/sugar transport protein; Region: MFS_2; pfam13347
926570005965	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
926570005966	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
926570005967	active site
926570005968	metal binding site [ion binding]; metal-binding site
926570005969	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
926570005970	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570005971	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570005972	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926570005973	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926570005974	E3 interaction surface; other site
926570005975	lipoyl attachment site [posttranslational modification]; other site
926570005976	e3 binding domain; Region: E3_binding; pfam02817
926570005977	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11857
926570005978	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926570005979	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
926570005980	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
926570005981	TPP-binding site [chemical binding]; other site
926570005982	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
926570005983	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
926570005984	CoA binding domain; Region: CoA_binding; smart00881
926570005985	CoA-ligase; Region: Ligase_CoA; pfam00549
926570005986	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
926570005987	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
926570005988	CoA-ligase; Region: Ligase_CoA; pfam00549
926570005989	Predicted ATPase [General function prediction only]; Region: COG1485
926570005990	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
926570005991	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
926570005992	aspartate aminotransferase; Provisional; Region: PRK05764
926570005993	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570005994	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570005995	homodimer interface [polypeptide binding]; other site
926570005996	catalytic residue [active]
926570005997	FOG: CBS domain [General function prediction only]; Region: COG0517
926570005998	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection...; Region: CBS_pair_BON_assoc; cd04586
926570005999	BON domain; Region: BON; pfam04972
926570006000	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926570006001	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926570006002	ligand binding site [chemical binding]; other site
926570006003	flexible hinge region; other site
926570006004	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
926570006005	putative switch regulator; other site
926570006006	non-specific DNA interactions [nucleotide binding]; other site
926570006007	DNA binding site [nucleotide binding]
926570006008	sequence specific DNA binding site [nucleotide binding]; other site
926570006009	putative cAMP binding site [chemical binding]; other site
926570006010	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
926570006011	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
926570006012	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
926570006013	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
926570006014	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
926570006015	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570006016	Walker A/P-loop; other site
926570006017	ATP binding site [chemical binding]; other site
926570006018	Q-loop/lid; other site
926570006019	ABC transporter signature motif; other site
926570006020	Walker B; other site
926570006021	D-loop; other site
926570006022	H-loop/switch region; other site
926570006023	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
926570006024	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926570006025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570006026	Walker A/P-loop; other site
926570006027	ATP binding site [chemical binding]; other site
926570006028	Q-loop/lid; other site
926570006029	ABC transporter signature motif; other site
926570006030	Walker B; other site
926570006031	D-loop; other site
926570006032	H-loop/switch region; other site
926570006033	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
926570006034	ClC chloride channel family. These protein sequences, closely related to the ClC Eric family, are putative halogen ion (Cl-, Br- and I-) transport proteins found in eubacteria. They belong to the ClC superfamily of chloride ion channels, which share a...; Region: EriC_like; cd01034
926570006035	putative ion selectivity filter; other site
926570006036	putative pore gating glutamate residue; other site
926570006037	putative H+/Cl- coupling transport residue; other site
926570006038	OsmC-like protein; Region: OsmC; pfam02566
926570006039	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
926570006040	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
926570006041	short chain dehydrogenase; Provisional; Region: PRK08339
926570006042	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344
926570006043	putative NAD(P) binding site [chemical binding]; other site
926570006044	putative active site [active]
926570006045	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
926570006046	CoA-transferase family III; Region: CoA_transf_3; pfam02515
926570006047	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
926570006048	chaperone protein DnaJ; Provisional; Region: PRK10767
926570006049	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
926570006050	HSP70 interaction site [polypeptide binding]; other site
926570006051	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
926570006052	Zn binding sites [ion binding]; other site
926570006053	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
926570006054	dimer interface [polypeptide binding]; other site
926570006055	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
926570006056	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
926570006057	nucleotide binding site [chemical binding]; other site
926570006058	NEF interaction site [polypeptide binding]; other site
926570006059	SBD interface [polypeptide binding]; other site
926570006060	GrpE; Region: GrpE; pfam01025
926570006061	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
926570006062	dimer interface [polypeptide binding]; other site
926570006063	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
926570006064	short chain dehydrogenase; Provisional; Region: PRK09134
926570006065	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570006066	NAD(P) binding site [chemical binding]; other site
926570006067	active site
926570006068	Methyltransferase domain; Region: Methyltransf_24; pfam13578
926570006069	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
926570006070	Homoserine Kinase, type II. Homoserine kinase is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; Region: HomoserineK_II; cd05153
926570006071	putative active site [active]
926570006072	putative substrate binding site [chemical binding]; other site
926570006073	ATP binding site [chemical binding]; other site
926570006074	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
926570006075	RNA/DNA hybrid binding site [nucleotide binding]; other site
926570006076	active site
926570006077	short chain dehydrogenase; Provisional; Region: PRK07060
926570006078	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570006079	NAD(P) binding site [chemical binding]; other site
926570006080	active site
926570006081	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926570006082	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
926570006083	Walker A/P-loop; other site
926570006084	ATP binding site [chemical binding]; other site
926570006085	Q-loop/lid; other site
926570006086	ABC transporter signature motif; other site
926570006087	Walker B; other site
926570006088	D-loop; other site
926570006089	H-loop/switch region; other site
926570006090	TOBE domain; Region: TOBE_2; pfam08402
926570006091	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926570006092	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570006093	dimer interface [polypeptide binding]; other site
926570006094	conserved gate region; other site
926570006095	putative PBP binding loops; other site
926570006096	ABC-ATPase subunit interface; other site
926570006097	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570006098	dimer interface [polypeptide binding]; other site
926570006099	conserved gate region; other site
926570006100	putative PBP binding loops; other site
926570006101	ABC-ATPase subunit interface; other site
926570006102	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926570006103	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926570006104	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926570006105	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926570006106	NAD(P) binding site [chemical binding]; other site
926570006107	L-fuculokinase; Provisional; Region: PRK10331
926570006108	uncharacterized ygcE-like proteins; Region: FGGY_ygcE_like; cd07779
926570006109	putative N- and C-terminal domain interface [polypeptide binding]; other site
926570006110	putative active site [active]
926570006111	MgATP binding site [chemical binding]; other site
926570006112	catalytic site [active]
926570006113	metal binding site [ion binding]; metal-binding site
926570006114	putative carbohydrate binding site [chemical binding]; other site
926570006115	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
926570006116	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
926570006117	YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function.  YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase.   Other enzymes with this fold include the peroxisomal...; Region: YdeM; cd03454
926570006118	putative active site [active]
926570006119	putative catalytic site [active]
926570006120	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
926570006121	Uncharacterized protein conserved in archaea (DUF2111); Region: DUF2111; cl01667
926570006122	ribonuclease PH; Reviewed; Region: rph; PRK00173
926570006123	Ribonuclease PH; Region: RNase_PH_bact; cd11362
926570006124	hexamer interface [polypeptide binding]; other site
926570006125	active site
926570006126	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
926570006127	active site
926570006128	dimerization interface [polypeptide binding]; other site
926570006129	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
926570006130	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
926570006131	active site
926570006132	dimer interface [polypeptide binding]; other site
926570006133	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
926570006134	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
926570006135	active site
926570006136	FMN binding site [chemical binding]; other site
926570006137	substrate binding site [chemical binding]; other site
926570006138	3Fe-4S cluster binding site [ion binding]; other site
926570006139	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
926570006140	domain interface; other site
926570006141	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
926570006142	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926570006143	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570006144	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570006145	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271
926570006146	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
926570006147	putative NAD(P) binding site [chemical binding]; other site
926570006148	active site
926570006149	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
926570006150	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
926570006151	catalytic site [active]
926570006152	putative active site [active]
926570006153	putative substrate binding site [chemical binding]; other site
926570006154	KpsF/GutQ family protein; Region: kpsF; TIGR00393
926570006155	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
926570006156	putative active site [active]
926570006157	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
926570006158	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5375
926570006159	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
926570006160	OstA-like protein; Region: OstA; cl00844
926570006161	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
926570006162	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
926570006163	Walker A/P-loop; other site
926570006164	ATP binding site [chemical binding]; other site
926570006165	Q-loop/lid; other site
926570006166	ABC transporter signature motif; other site
926570006167	Walker B; other site
926570006168	D-loop; other site
926570006169	H-loop/switch region; other site
926570006170	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
926570006171	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
926570006172	5S rRNA interface [nucleotide binding]; other site
926570006173	CTC domain interface [polypeptide binding]; other site
926570006174	L16 interface [polypeptide binding]; other site
926570006175	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
926570006176	putative active site [active]
926570006177	catalytic residue [active]
926570006178	GTP-binding protein YchF; Reviewed; Region: PRK09601
926570006179	YchF GTPase; Region: YchF; cd01900
926570006180	G1 box; other site
926570006181	GTP/Mg2+ binding site [chemical binding]; other site
926570006182	Switch I region; other site
926570006183	G2 box; other site
926570006184	Switch II region; other site
926570006185	G3 box; other site
926570006186	G4 box; other site
926570006187	G5 box; other site
926570006188	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
926570006189	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570006190	primosomal protein N' Region: priA; TIGR00595
926570006191	ATP binding site [chemical binding]; other site
926570006192	putative Mg++ binding site [ion binding]; other site
926570006193	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
926570006194	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
926570006195	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
926570006196	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
926570006197	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
926570006198	beta subunit interaction interface [polypeptide binding]; other site
926570006199	Walker A motif; other site
926570006200	ATP binding site [chemical binding]; other site
926570006201	Walker B motif; other site
926570006202	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
926570006203	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
926570006204	core domain interface [polypeptide binding]; other site
926570006205	delta subunit interface [polypeptide binding]; other site
926570006206	epsilon subunit interface [polypeptide binding]; other site
926570006207	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
926570006208	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
926570006209	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
926570006210	alpha subunit interaction interface [polypeptide binding]; other site
926570006211	Walker A motif; other site
926570006212	ATP binding site [chemical binding]; other site
926570006213	Walker B motif; other site
926570006214	inhibitor binding site; inhibition site
926570006215	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
926570006216	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
926570006217	gamma subunit interface [polypeptide binding]; other site
926570006218	epsilon subunit interface [polypeptide binding]; other site
926570006219	LBP interface [polypeptide binding]; other site
926570006220	Malonyl-CoA decarboxylase (MCD); Region: MCD; pfam05292
926570006221	benzoate transport; Region: 2A0115; TIGR00895
926570006222	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570006223	putative substrate translocation pore; other site
926570006224	squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507
926570006225	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
926570006226	Active site cavity [active]
926570006227	catalytic acid [active]
926570006228	peptide chain release factor 2; Provisional; Region: PRK07342
926570006229	This domain is found in peptide chain release factors; Region: PCRF; smart00937
926570006230	RF-1 domain; Region: RF-1; pfam00472
926570006231	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
926570006232	Transglycosylase; Region: Transgly; pfam00912
926570006233	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
926570006234	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
926570006235	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
926570006236	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
926570006237	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
926570006238	Tripartite ATP-independent periplasmic transporters, DctQ component; Region: DctQ; cl01181
926570006239	DctM-like transporters; Region: DctM; pfam06808
926570006240	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
926570006241	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
926570006242	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570006243	NAD(P) binding site [chemical binding]; other site
926570006244	active site
926570006245	coproporphyrinogen III oxidase; Provisional; Region: PRK09057
926570006246	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570006247	FeS/SAM binding site; other site
926570006248	HemN C-terminal domain; Region: HemN_C; pfam06969
926570006249	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
926570006250	rRNA interaction site [nucleotide binding]; other site
926570006251	S8 interaction site; other site
926570006252	putative laminin-1 binding site; other site
926570006253	elongation factor Ts; Provisional; Region: tsf; PRK09377
926570006254	UBA/TS-N domain; Region: UBA; pfam00627
926570006255	Elongation factor TS; Region: EF_TS; pfam00889
926570006256	Elongation factor TS; Region: EF_TS; pfam00889
926570006257	PAS domain; Region: PAS_9; pfam13426
926570006258	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570006259	PAS domain; Region: PAS_9; pfam13426
926570006260	putative active site [active]
926570006261	heme pocket [chemical binding]; other site
926570006262	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570006263	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570006264	dimer interface [polypeptide binding]; other site
926570006265	putative CheW interface [polypeptide binding]; other site
926570006266	Uncharacterized conserved protein [Function unknown]; Region: COG3791
926570006267	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
926570006268	5-methyltetrahydrofolate--homocysteine methyltransferase; Region: metH; TIGR02082
926570006269	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
926570006270	substrate binding pocket [chemical binding]; other site
926570006271	dimer interface [polypeptide binding]; other site
926570006272	inhibitor binding site; inhibition site
926570006273	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
926570006274	B12 binding site [chemical binding]; other site
926570006275	cobalt ligand [ion binding]; other site
926570006276	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
926570006277	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
926570006278	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
926570006279	elongation factor P; Validated; Region: PRK00529
926570006280	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
926570006281	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
926570006282	RNA binding site [nucleotide binding]; other site
926570006283	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
926570006284	RNA binding site [nucleotide binding]; other site
926570006285	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926570006286	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
926570006287	active site
926570006288	dimerization interface [polypeptide binding]; other site
926570006289	OmpA family; Region: OmpA; pfam00691
926570006290	hypothetical protein; Validated; Region: PRK09039
926570006291	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570006292	ligand binding site [chemical binding]; other site
926570006293	Cobalamin biosynthesis protein CobT; Region: CobT; pfam06213
926570006294	norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role  in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454
926570006295	metal ion-dependent adhesion site (MIDAS); other site
926570006296	Cobaltochelatase CobS subunit N terminal; Region: CobS_N; pfam12556
926570006297	cobaltochelatase, CobS subunit; Region: PD_CobS; TIGR01650
926570006298	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
926570006299	Walker A motif; other site
926570006300	ATP binding site [chemical binding]; other site
926570006301	Walker B motif; other site
926570006302	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
926570006303	HSP70 interaction site [polypeptide binding]; other site
926570006304	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
926570006305	acylglycerophosphoethanolamine acyltransferase; Provisional; Region: PRK06814
926570006306	enoyl-CoA hydratase; Provisional; Region: PRK08140
926570006307	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570006308	substrate binding site [chemical binding]; other site
926570006309	oxyanion hole (OAH) forming residues; other site
926570006310	trimer interface [polypeptide binding]; other site
926570006311	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
926570006312	catalytic nucleophile [active]
926570006313	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
926570006314	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
926570006315	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
926570006316	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
926570006317	GTP binding site; other site
926570006318	MarC family integral membrane protein; Region: MarC; pfam01914
926570006319	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
926570006320	IHF dimer interface [polypeptide binding]; other site
926570006321	IHF - DNA interface [nucleotide binding]; other site
926570006322	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
926570006323	active site
926570006324	dimer interface [polypeptide binding]; other site
926570006325	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
926570006326	active site
926570006327	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
926570006328	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
926570006329	DNA binding site [nucleotide binding]
926570006330	catalytic residue [active]
926570006331	H2TH interface [polypeptide binding]; other site
926570006332	putative catalytic residues [active]
926570006333	turnover-facilitating residue; other site
926570006334	intercalation triad [nucleotide binding]; other site
926570006335	8OG recognition residue [nucleotide binding]; other site
926570006336	putative reading head residues; other site
926570006337	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
926570006338	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
926570006339	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
926570006340	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570006341	S-adenosylmethionine binding site [chemical binding]; other site
926570006342	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
926570006343	Flavoprotein; Region: Flavoprotein; pfam02441
926570006344	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
926570006345	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
926570006346	trimer interface [polypeptide binding]; other site
926570006347	active site
926570006348	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570006349	NAD(P) binding site [chemical binding]; other site
926570006350	active site
926570006351	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
926570006352	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
926570006353	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
926570006354	catalytic core [active]
926570006355	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
926570006356	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
926570006357	dimer interface [polypeptide binding]; other site
926570006358	active site
926570006359	citrylCoA binding site [chemical binding]; other site
926570006360	NADH binding [chemical binding]; other site
926570006361	cationic pore residues; other site
926570006362	oxalacetate/citrate binding site [chemical binding]; other site
926570006363	coenzyme A binding site [chemical binding]; other site
926570006364	catalytic triad [active]
926570006365	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570006366	dimerization interface [polypeptide binding]; other site
926570006367	putative DNA binding site [nucleotide binding]; other site
926570006368	putative Zn2+ binding site [ion binding]; other site
926570006369	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
926570006370	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
926570006371	FMN binding site [chemical binding]; other site
926570006372	active site
926570006373	substrate binding site [chemical binding]; other site
926570006374	catalytic residue [active]
926570006375	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926570006376	classical (c) SDRs; Region: SDR_c; cd05233
926570006377	NAD(P) binding site [chemical binding]; other site
926570006378	active site
926570006379	PA14 domain; Region: PA14; cl08459
926570006380	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926570006381	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926570006382	DNA binding residues [nucleotide binding]
926570006383	dimerization interface [polypeptide binding]; other site
926570006384	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
926570006385	quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein; Region: ABC_peri_MoxJ_2; TIGR03871
926570006386	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
926570006387	Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); Region: PQQ_ADH_I; cd10277
926570006388	dimer interface [polypeptide binding]; other site
926570006389	Trp docking motif [polypeptide binding]; other site
926570006390	active site
926570006391	Protein of unknown function (DUF779); Region: DUF779; pfam05610
926570006392	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
926570006393	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
926570006394	NAD(P) binding site [chemical binding]; other site
926570006395	catalytic residues [active]
926570006396	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
926570006397	GAF domain; Region: GAF; pfam01590
926570006398	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570006399	Walker A motif; other site
926570006400	ATP binding site [chemical binding]; other site
926570006401	Walker B motif; other site
926570006402	arginine finger; other site
926570006403	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570006404	N-formimino-L-glutamate deiminase; Validated; Region: PRK09229
926570006405	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570006406	active site
926570006407	imidazolonepropionase; Validated; Region: PRK09356
926570006408	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570006409	active site
926570006410	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
926570006411	active sites [active]
926570006412	tetramer interface [polypeptide binding]; other site
926570006413	N-formylglutamate amidohydrolase; Region: FGase; cl01522
926570006414	urocanate hydratase; Provisional; Region: PRK05414
926570006415	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
926570006416	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570006417	DNA-binding site [nucleotide binding]; DNA binding site
926570006418	UTRA domain; Region: UTRA; pfam07702
926570006419	N-formylglutamate amidohydrolase; Region: FGase; pfam05013
926570006420	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
926570006421	Domain of unknown function (DUF4168); Region: DUF4168; pfam13767
926570006422	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
926570006423	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
926570006424	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570006425	ATP binding site [chemical binding]; other site
926570006426	putative Mg++ binding site [ion binding]; other site
926570006427	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570006428	nucleotide binding region [chemical binding]; other site
926570006429	ATP-binding site [chemical binding]; other site
926570006430	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
926570006431	Flavinator of succinate dehydrogenase; Region: Sdh5; pfam03937
926570006432	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
926570006433	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
926570006434	generic binding surface II; other site
926570006435	ssDNA binding site; other site
926570006436	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570006437	ATP binding site [chemical binding]; other site
926570006438	putative Mg++ binding site [ion binding]; other site
926570006439	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570006440	nucleotide binding region [chemical binding]; other site
926570006441	ATP-binding site [chemical binding]; other site
926570006442	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_15; cd04673
926570006443	nudix motif; other site
926570006444	TMAO/DMSO reductase; Reviewed; Region: PRK05363
926570006445	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
926570006446	Moco binding site; other site
926570006447	metal coordination site [ion binding]; other site
926570006448	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
926570006449	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
926570006450	homodimer interface [polypeptide binding]; other site
926570006451	metal binding site [ion binding]; metal-binding site
926570006452	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
926570006453	homodimer interface [polypeptide binding]; other site
926570006454	active site
926570006455	putative chemical substrate binding site [chemical binding]; other site
926570006456	metal binding site [ion binding]; metal-binding site
926570006457	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926570006458	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
926570006459	active site
926570006460	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
926570006461	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
926570006462	HflX GTPase family; Region: HflX; cd01878
926570006463	G1 box; other site
926570006464	GTP/Mg2+ binding site [chemical binding]; other site
926570006465	Switch I region; other site
926570006466	G2 box; other site
926570006467	G3 box; other site
926570006468	Switch II region; other site
926570006469	G4 box; other site
926570006470	G5 box; other site
926570006471	bacterial Hfq-like; Region: Hfq; cd01716
926570006472	hexamer interface [polypeptide binding]; other site
926570006473	Sm1 motif; other site
926570006474	RNA binding site [nucleotide binding]; other site
926570006475	Sm2 motif; other site
926570006476	Hint domain; Region: Hint_2; pfam13403
926570006477	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570006478	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570006479	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570006480	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570006481	Hint domain; Region: Hint_2; pfam13403
926570006482	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
926570006483	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
926570006484	Ligand Binding Site [chemical binding]; other site
926570006485	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
926570006486	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570006487	catalytic loop [active]
926570006488	iron binding site [ion binding]; other site
926570006489	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926570006490	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
926570006491	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570006492	catalytic residue [active]
926570006493	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
926570006494	serine O-acetyltransferase; Region: cysE; TIGR01172
926570006495	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
926570006496	trimer interface [polypeptide binding]; other site
926570006497	active site
926570006498	substrate binding site [chemical binding]; other site
926570006499	CoA binding site [chemical binding]; other site
926570006500	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
926570006501	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926570006502	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
926570006503	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
926570006504	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926570006505	ROS/MUCR transcriptional regulator protein; Region: ROS_MUCR; pfam05443
926570006506	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
926570006507	CPxP  motif; other site
926570006508	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926570006509	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
926570006510	Glycoprotease family; Region: Peptidase_M22; pfam00814
926570006511	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
926570006512	putative FMN binding site [chemical binding]; other site
926570006513	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
926570006514	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
926570006515	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
926570006516	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570006517	Methyltransferase domain; Region: Methyltransf_11; pfam08241
926570006518	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
926570006519	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
926570006520	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570006521	acyl-activating enzyme (AAE) consensus motif; other site
926570006522	AMP binding site [chemical binding]; other site
926570006523	active site
926570006524	CoA binding site [chemical binding]; other site
926570006525	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
926570006526	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
926570006527	Protein of unknown function (DUF2497); Region: DUF2497; pfam10691
926570006528	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
926570006529	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
926570006530	active site
926570006531	HIGH motif; other site
926570006532	nucleotide binding site [chemical binding]; other site
926570006533	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
926570006534	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
926570006535	active site
926570006536	KMSKS motif; other site
926570006537	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
926570006538	tRNA binding surface [nucleotide binding]; other site
926570006539	anticodon binding site; other site
926570006540	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
926570006541	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
926570006542	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
926570006543	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
926570006544	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
926570006545	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
926570006546	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
926570006547	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
926570006548	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
926570006549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570006550	catalytic residue [active]
926570006551	preprotein translocase subunit SecB; Validated; Region: PRK05751
926570006552	SecA binding site; other site
926570006553	Preprotein binding site; other site
926570006554	N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863
926570006555	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
926570006556	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
926570006557	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
926570006558	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
926570006559	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
926570006560	tetrameric interface [polypeptide binding]; other site
926570006561	NAD binding site [chemical binding]; other site
926570006562	catalytic residues [active]
926570006563	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570006564	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570006565	LysR substrate binding domain; Region: LysR_substrate; pfam03466
926570006566	dimerization interface [polypeptide binding]; other site
926570006567	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
926570006568	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926570006569	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570006570	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926570006571	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
926570006572	Walker A/P-loop; other site
926570006573	ATP binding site [chemical binding]; other site
926570006574	Q-loop/lid; other site
926570006575	ABC transporter signature motif; other site
926570006576	Walker B; other site
926570006577	D-loop; other site
926570006578	H-loop/switch region; other site
926570006579	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
926570006580	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926570006581	Walker A/P-loop; other site
926570006582	ATP binding site [chemical binding]; other site
926570006583	Q-loop/lid; other site
926570006584	ABC transporter signature motif; other site
926570006585	Walker B; other site
926570006586	D-loop; other site
926570006587	H-loop/switch region; other site
926570006588	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
926570006589	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
926570006590	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
926570006591	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
926570006592	hybrid cluster protein; Provisional; Region: PRK05290
926570006593	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926570006594	ACS interaction site; other site
926570006595	CODH interaction site; other site
926570006596	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926570006597	ACS interaction site; other site
926570006598	CODH interaction site; other site
926570006599	metal cluster binding site [ion binding]; other site
926570006600	anthranilate dioxygenase reductase; Provisional; Region: antC; PRK11872
926570006601	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570006602	catalytic loop [active]
926570006603	iron binding site [ion binding]; other site
926570006604	Methane monooxygenase (MMO) reductase of methanotrophs catalyzes the NADH-dependent hydroxylation of methane to methanol. This multicomponent enzyme mediates electron transfer via a hydroxylase (MMOH), a coupling protein, and a reductase which is...; Region: MMO_FAD_NAD_binding; cd06210
926570006605	FAD binding pocket [chemical binding]; other site
926570006606	FAD binding motif [chemical binding]; other site
926570006607	phosphate binding motif [ion binding]; other site
926570006608	beta-alpha-beta structure motif; other site
926570006609	NAD binding pocket [chemical binding]; other site
926570006610	Transcriptional regulator; Region: Rrf2; cl17282
926570006611	Rrf2 family protein; Region: rrf2_super; TIGR00738
926570006612	Protein involved in cellulose biosynthesis (CelD) [Cell envelope biogenesis, outer membrane]; Region: COG5653
926570006613	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
926570006614	Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs; Region: CE4_WalW; cd10935
926570006615	putative active site [active]
926570006616	putative catalytic site [active]
926570006617	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570006618	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
926570006619	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
926570006620	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
926570006621	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926570006622	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp2; TIGR03088
926570006623	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570006624	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
926570006625	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
926570006626	dimer interface [polypeptide binding]; other site
926570006627	active site
926570006628	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
926570006629	Ligand Binding Site [chemical binding]; other site
926570006630	Molecular Tunnel; other site
926570006631	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
926570006632	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
926570006633	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926570006634	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570006635	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926570006636	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926570006637	Probable Catalytic site; other site
926570006638	metal-binding site
926570006639	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926570006640	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926570006641	Probable Catalytic site; other site
926570006642	metal-binding site
926570006643	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
926570006644	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
926570006645	HTH-like domain; Region: HTH_21; pfam13276
926570006646	Integrase core domain; Region: rve; pfam00665
926570006647	Integrase core domain; Region: rve_3; pfam13683
926570006648	Transposase; Region: HTH_Tnp_1; pfam01527
926570006649	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
926570006650	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
926570006651	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570006652	MULE transposase domain; Region: MULE; pfam10551
926570006653	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
926570006654	Cytochrome C subunit of the bacterial photosynthetic reaction center; Region: CytoC_RC; cd09224
926570006655	subunit interface [polypeptide binding]; other site
926570006656	Heme binding sites [chemical binding]; other site
926570006657	photosynthetic reaction center subunit M; Provisional; Region: PRK14504
926570006658	pheophytin binding site; other site
926570006659	chlorophyll binding site; other site
926570006660	quinone binding site; other site
926570006661	Fe binding site [ion binding]; other site
926570006662	Subunit L of bacterial photosynthetic reaction center; Region: Photo-RC_L; cd09290
926570006663	subunit M interface; other site
926570006664	subunit H interface; other site
926570006665	quinone binding site; other site
926570006666	bacteriopheophytin binding site; other site
926570006667	bacteriochlorophyll binding site; other site
926570006668	cytochrome C subunit interface; other site
926570006669	Fe binding site [ion binding]; other site
926570006670	Antenna complex alpha/beta subunit; Region: LHC; pfam00556
926570006671	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
926570006672	chlorophyllide reductase subunit Z; Region: BchZ; TIGR02014
926570006673	chlorophyllide reductase subunit Y; Region: BchY; TIGR02015
926570006674	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
926570006675	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926570006676	chlorophyllide reductase iron protein subunit X; Region: BchX; TIGR02016
926570006677	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; Region: bchC; TIGR01202
926570006678	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926570006679	NAD(P) binding site [chemical binding]; other site
926570006680	O-methyltransferase; Region: Methyltransf_2; pfam00891
926570006681	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
926570006682	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
926570006683	substrate binding pocket [chemical binding]; other site
926570006684	substrate-Mg2+ binding site; other site
926570006685	aspartate-rich region 1; other site
926570006686	aspartate-rich region 2; other site
926570006687	phytoene desaturase; Region: crtI_fam; TIGR02734
926570006688	Hydroxyneurosporene synthase (CrtC); Region: CrtC; pfam07143
926570006689	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
926570006690	active site lid residues [active]
926570006691	substrate binding pocket [chemical binding]; other site
926570006692	catalytic residues [active]
926570006693	substrate-Mg2+ binding site; other site
926570006694	aspartate-rich region 1; other site
926570006695	aspartate-rich region 2; other site
926570006696	phytoene desaturase; Region: crtI_fam; TIGR02734
926570006697	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926570006698	putative magnesium chelatase accessory protein; Region: bchO_mg_che_rel; TIGR03056
926570006699	magnesium chelatase subunit D; Provisional; Region: bchD; PRK13406
926570006700	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
926570006701	metal ion-dependent adhesion site (MIDAS); other site
926570006702	magnesium chelatase subunit I; Provisional; Region: bchI; PRK13407
926570006703	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
926570006704	TspO/MBR family; Region: TspO_MBR; pfam03073
926570006705	geranylgeranyl reductase; Region: BchP-ChlP; TIGR02023
926570006706	bacteriochlorophyll/chlorophyll a synthase; Reviewed; Region: PRK07566
926570006707	UbiA prenyltransferase family; Region: UbiA; pfam01040
926570006708	transcriptional regulator PpsR; Region: PpsR-CrtJ; TIGR02040
926570006709	PAS domain; Region: PAS; smart00091
926570006710	putative active site [active]
926570006711	heme pocket [chemical binding]; other site
926570006712	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570006713	putative active site [active]
926570006714	heme pocket [chemical binding]; other site
926570006715	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570006716	B12 binding domain; Region: B12-binding_2; cl03653
926570006717	B12 binding domain; Region: B12-binding; pfam02310
926570006718	B12 binding site [chemical binding]; other site
926570006719	2-vinyl bacteriochlorophyllide hydratase (BCHF); Region: BCHF; pfam07284
926570006720	light-independent protochlorophyllide reductase subunit N; Provisional; Region: PRK02842
926570006721	light-independent protochlorophyllide reductase, N subunit; Region: DPOR_bchN; TIGR01279
926570006722	light-independent protochlorophyllide reductase subunit B; Provisional; Region: PRK02910
926570006723	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
926570006724	Proto-chlorophyllide reductase 57 kD subunit; Region: PCP_red; pfam08369
926570006725	magnesium chelatase subunit H; Provisional; Region: bchH; PRK13405
926570006726	Domain of unknown function (DUF3479); Region: DUF3479; pfam11965
926570006727	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
926570006728	protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional; Region: chlL; PRK13185
926570006729	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926570006730	Mg-protoporphyrin IX methyl transferase; Validated; Region: PRK07580
926570006731	Methyltransferase domain; Region: Methyltransf_18; pfam12847
926570006732	Magnesium-protoporphyrin IX methyltransferase C-terminus; Region: Mg-por_mtran_C; pfam07109
926570006733	PUCC protein; Region: PUCC; pfam03209
926570006734	photosynthetic reaction center, subunit H, bacterial; Region: puhA; TIGR01150
926570006735	Photosynthetic reaction center (RC) complex, subunit H;  RC is an integral membrane protein-pigment complex which catalyzes light-induced reduction of ubiquinone to ubiquinol, generating a transmembrane electrochemical gradient of protons used to produce...; Region: PRCH; cl17581
926570006736	subunit C interaction residues; other site
926570006737	subunit M interaction residues [polypeptide binding]; other site
926570006738	subunit L interaction residues [polypeptide binding]; other site
926570006739	putative proton transfer pathway, P1; other site
926570006740	putative proton transfer pathway, P2; other site
926570006741	Bacterial PH domain; Region: DUF304; cl01348
926570006742	putative photosynthetic complex assembly protein; Region: photo_alph_chp1; TIGR03054
926570006743	Aerobic Cyclase System Fe-containing subunit (ACSF), ferritin-like diiron-binding domain; Region: ACSF; cd01047
926570006744	diiron binding motif [ion binding]; other site
926570006745	Protein of unknown function (DUF3623); Region: DUF3623; pfam12291
926570006746	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
926570006747	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
926570006748	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
926570006749	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
926570006750	substrate-cofactor binding pocket; other site
926570006751	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570006752	catalytic residue [active]
926570006753	Integrase core domain; Region: rve_3; pfam13683
926570006754	Transposase; Region: HTH_Tnp_1; cl17663
926570006755	Cytochrome c; Region: Cytochrom_C; cl11414
926570006756	Cytochrome c; Region: Cytochrom_C; cl11414
926570006757	Cytochrome c [Energy production and conversion]; Region: COG3258
926570006758	Cytochrome c; Region: Cytochrom_C; pfam00034
926570006759	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
926570006760	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926570006761	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570006762	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570006763	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570006764	potential frameshift: common BLAST hit: gi|148243732|ref|YP_001219972.1| transposase, IS4 family protein
926570006765	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570006766	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570006767	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570006768	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570006769	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570006770	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570006771	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570006772	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926570006773	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570006774	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
926570006775	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
926570006776	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK12786
926570006777	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
926570006778	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12691
926570006779	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
926570006780	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
926570006781	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12690
926570006782	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
926570006783	DNA Polymerase Y-family; Region: PolY_like; cd03468
926570006784	DNA binding site [nucleotide binding]
926570006785	error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672
926570006786	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at DnaE2 gene; Region: PHP_PolIIIA_DnaE2; cd07434
926570006787	putative active site [active]
926570006788	putative PHP Thumb interface [polypeptide binding]; other site
926570006789	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
926570006790	generic binding surface I; other site
926570006791	generic binding surface II; other site
926570006792	Flagellar basal body-associated protein FliL; Region: FliL; cl00681
926570006793	Uncharacterized conserved protein [Function unknown]; Region: COG3334
926570006794	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522; cl01406
926570006795	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570006796	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570006797	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570006798	Integrase core domain; Region: rve; pfam00665
926570006799	Integrase core domain; Region: rve_3; pfam13683
926570006800	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570006801	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_2; cd08464
926570006802	putative substrate binding pocket [chemical binding]; other site
926570006803	putative dimerization interface [polypeptide binding]; other site
926570006804	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
926570006805	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
926570006806	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926570006807	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
926570006808	Helix-turn-helix domain; Region: HTH_18; pfam12833
926570006809	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
926570006810	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
926570006811	Autotransporter beta-domain; Region: Autotransporter; pfam03797
926570006812	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570006813	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570006814	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570006815	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926570006816	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
926570006817	putative DNA binding site [nucleotide binding]; other site
926570006818	putative Zn2+ binding site [ion binding]; other site
926570006819	AsnC family; Region: AsnC_trans_reg; pfam01037
926570006820	Arginase family; Region: Arginase; cd09989
926570006821	active site
926570006822	Mn binding site [ion binding]; other site
926570006823	oligomer interface [polypeptide binding]; other site
926570006824	ornithine cyclodeaminase; Validated; Region: PRK07589
926570006825	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
926570006826	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926570006827	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
926570006828	catalytic site [active]
926570006829	TAP-like protein; Region: Abhydrolase_4; pfam08386
926570006830	Protein of unknown function (DUF962); Region: DUF962; cl01879
926570006831	Poly-beta-hydroxybutyrate polymerase N terminal; Region: PHBC_N; pfam12551
926570006832	poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838
926570006833	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
926570006834	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570006835	MULE transposase domain; Region: MULE; pfam10551
926570006836	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570006837	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570006838	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
926570006839	Transposase domain (DUF772); Region: DUF772; pfam05598
926570006840	Cupin; Region: Cupin_6; pfam12852
926570006841	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
926570006842	short chain dehydrogenase; Provisional; Region: PRK06180
926570006843	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
926570006844	NADP binding site [chemical binding]; other site
926570006845	active site
926570006846	steroid binding site; other site
926570006847	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
926570006848	NmrA-like family; Region: NmrA; pfam05368
926570006849	NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs; Region: NmrA_like_SDR_a; cd05251
926570006850	NADP binding site [chemical binding]; other site
926570006851	active site
926570006852	regulatory binding site [polypeptide binding]; other site
926570006853	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570006854	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570006855	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570006856	dimerization interface [polypeptide binding]; other site
926570006857	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
926570006858	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
926570006859	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570006860	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570006861	dimerization interface [polypeptide binding]; other site
926570006862	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; cl17722
926570006863	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570006864	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
926570006865	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926570006866	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
926570006867	NAD binding site [chemical binding]; other site
926570006868	Amidohydrolase; Region: Amidohydro_2; pfam04909
926570006869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570006870	D-galactonate transporter; Region: 2A0114; TIGR00893
926570006871	putative substrate translocation pore; other site
926570006872	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570006873	hypothetical protein; Validated; Region: PRK06201
926570006874	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
926570006875	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
926570006876	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570006877	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
926570006878	dimerization interface [polypeptide binding]; other site
926570006879	substrate binding pocket [chemical binding]; other site
926570006880	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
926570006881	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570006882	active site
926570006883	5-oxoprolinase; Region: PLN02666
926570006884	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
926570006885	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
926570006886	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
926570006887	MarR family; Region: MarR_2; cl17246
926570006888	benzoate transport; Region: 2A0115; TIGR00895
926570006889	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570006890	putative substrate translocation pore; other site
926570006891	HTH-like domain; Region: HTH_21; pfam13276
926570006892	Integrase core domain; Region: rve; pfam00665
926570006893	Integrase core domain; Region: rve_3; pfam13683
926570006894	transposase; Validated; Region: PRK08181
926570006895	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570006896	Walker A motif; other site
926570006897	ATP binding site [chemical binding]; other site
926570006898	Walker B motif; other site
926570006899	Integrase core domain; Region: rve; pfam00665
926570006900	Transposase; Region: HTH_Tnp_1; pfam01527
926570006901	Integrase core domain; Region: rve; pfam00665
926570006902	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
926570006903	DNA binding residues [nucleotide binding]
926570006904	dimerization interface [polypeptide binding]; other site
926570006905	amino acid permease (GABA permease); Region: 2A0304; TIGR00907
926570006906	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
926570006907	classical (c) SDRs; Region: SDR_c; cd05233
926570006908	NAD(P) binding site [chemical binding]; other site
926570006909	active site
926570006910	FAD binding domain; Region: FAD_binding_4; pfam01565
926570006911	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
926570006912	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570006913	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570006914	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
926570006915	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926570006916	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
926570006917	putative DNA binding site [nucleotide binding]; other site
926570006918	putative Zn2+ binding site [ion binding]; other site
926570006919	Cupin domain; Region: Cupin_2; cl17218
926570006920	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570006921	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
926570006922	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570006923	EamA-like transporter family; Region: EamA; pfam00892
926570006924	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
926570006925	MmgE/PrpD family; Region: MmgE_PrpD; cl00912
926570006926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
926570006927	(2R)-phospho-3-sulfolactate synthase (ComA); Region: ComA; cl00782
926570006928	Predicted transcriptional regulators [Transcription]; Region: COG1378
926570006929	Sugar-specific transcriptional regulator TrmB; Region: TrmB; pfam01978
926570006930	Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins; Region: PLDc_like_TrmB_middle; cd09124
926570006931	C-terminal domain interface [polypeptide binding]; other site
926570006932	sugar binding site [chemical binding]; other site
926570006933	tricarballylate dehydrogenase; Validated; Region: PRK08274
926570006934	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
926570006935	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570006936	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570006937	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570006938	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570006939	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
926570006940	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926570006941	membrane-bound complex binding site; other site
926570006942	hinge residues; other site
926570006943	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926570006944	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570006945	dimer interface [polypeptide binding]; other site
926570006946	conserved gate region; other site
926570006947	putative PBP binding loops; other site
926570006948	ABC-ATPase subunit interface; other site
926570006949	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926570006950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570006951	dimer interface [polypeptide binding]; other site
926570006952	conserved gate region; other site
926570006953	putative PBP binding loops; other site
926570006954	ABC-ATPase subunit interface; other site
926570006955	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926570006956	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926570006957	Walker A/P-loop; other site
926570006958	ATP binding site [chemical binding]; other site
926570006959	Q-loop/lid; other site
926570006960	ABC transporter signature motif; other site
926570006961	Walker B; other site
926570006962	D-loop; other site
926570006963	H-loop/switch region; other site
926570006964	Transposase domain (DUF772); Region: DUF772; pfam05598
926570006965	HTH-like domain; Region: HTH_21; pfam13276
926570006966	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
926570006967	Integrase core domain; Region: rve; pfam00665
926570006968	Integrase core domain; Region: rve_3; pfam13683
926570006969	Transposase; Region: HTH_Tnp_1; pfam01527
926570006970	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
926570006971	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570006972	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570006973	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570006974	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570006975	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570006976	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570006977	MULE transposase domain; Region: MULE; pfam10551
926570006978	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
926570006979	ligand binding site [chemical binding]; other site
926570006980	dimer interface [polypeptide binding]; other site
926570006981	FRG domain; Region: FRG; pfam08867
926570006982	NIPSNAP; Region: NIPSNAP; pfam07978
926570006983	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570006984	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
926570006985	catalytic residues [active]
926570006986	catalytic nucleophile [active]
926570006987	Recombinase; Region: Recombinase; pfam07508
926570006988	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
926570006989	PAS fold; Region: PAS_4; pfam08448
926570006990	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
926570006991	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570006992	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570006993	metal binding site [ion binding]; metal-binding site
926570006994	active site
926570006995	I-site; other site
926570006996	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570006997	Transposase domain (DUF772); Region: DUF772; pfam05598
926570006998	DDE superfamily endonuclease; Region: DDE_4; cl17710
926570006999	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570007000	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
926570007001	Helix-turn-helix domain; Region: HTH_17; pfam12728
926570007002	Photosystem II reaction centre W protein (PsbW); Region: PsbW; cl06243
926570007003	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
926570007004	active site
926570007005	Int/Topo IB signature motif; other site
926570007006	catalytic residues [active]
926570007007	DNA binding site [nucleotide binding]
926570007008	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570007009	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570007010	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570007011	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570007012	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
926570007013	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570007014	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570007015	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570007016	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570007017	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926570007018	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
926570007019	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
926570007020	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
926570007021	Int/Topo IB signature motif; other site
926570007022	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
926570007023	Putative transposase; Region: Y2_Tnp; pfam04986
926570007024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570007025	AAA domain; Region: AAA_21; pfam13304
926570007026	Walker A/P-loop; other site
926570007027	ATP binding site [chemical binding]; other site
926570007028	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
926570007029	ABC transporter signature motif; other site
926570007030	Walker B; other site
926570007031	D-loop; other site
926570007032	H-loop/switch region; other site
926570007033	Transposase; Region: HTH_Tnp_1; pfam01527
926570007034	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
926570007035	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
926570007036	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
926570007037	potential frameshift: common BLAST hit: gi|222102307|ref|YP_002546897.1| transposase number 3 for insertion sequence
926570007038	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
926570007039	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
926570007040	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
926570007041	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
926570007042	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
926570007043	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
926570007044	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570007045	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
926570007046	catalytic residues [active]
926570007047	Recombinase; Region: Recombinase; pfam07508
926570007048	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
926570007049	choice-of-anchor C domain; Region: choice_anch_C; TIGR04362
926570007050	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
926570007051	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
926570007052	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570007053	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570007054	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570007055	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570007056	potential frameshift: common BLAST hit: gi|254562779|ref|YP_003069874.1| transposase of ISMdi7, IS21 family (ORF 1)
926570007057	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570007058	Integrase core domain; Region: rve; pfam00665
926570007059	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
926570007060	Predicted kinase [General function prediction only]; Region: COG4857; cl17281
926570007061	Transposase, Mutator family; Region: Transposase_mut; pfam00872
926570007062	MULE transposase domain; Region: MULE; pfam10551
926570007063	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570007064	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570007065	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570007066	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570007067	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570007068	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570007069	Transposase; Region: HTH_Tnp_1; pfam01527
926570007070	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570007071	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570007072	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570007073	Integrase core domain; Region: rve; pfam00665
926570007074	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
926570007075	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570007076	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570007077	Walker A/P-loop; other site
926570007078	ATP binding site [chemical binding]; other site
926570007079	Q-loop/lid; other site
926570007080	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570007081	ABC transporter signature motif; other site
926570007082	Walker B; other site
926570007083	D-loop; other site
926570007084	ABC transporter; Region: ABC_tran_2; pfam12848
926570007085	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570007086	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570007087	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
926570007088	catalytic residues [active]
926570007089	Recombinase; Region: Recombinase; pfam07508
926570007090	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
926570007091	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
926570007092	Clp amino terminal domain; Region: Clp_N; pfam02861
926570007093	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570007094	Walker A motif; other site
926570007095	ATP binding site [chemical binding]; other site
926570007096	Walker B motif; other site
926570007097	arginine finger; other site
926570007098	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570007099	Walker A motif; other site
926570007100	ATP binding site [chemical binding]; other site
926570007101	Walker B motif; other site
926570007102	arginine finger; other site
926570007103	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
926570007104	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
926570007105	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
926570007106	MOSC domain; Region: MOSC; pfam03473
926570007107	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
926570007108	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
926570007109	Walker A motif; other site
926570007110	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
926570007111	MoaE interaction surface [polypeptide binding]; other site
926570007112	MoeB interaction surface [polypeptide binding]; other site
926570007113	thiocarboxylated glycine; other site
926570007114	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
926570007115	MoaD interaction [polypeptide binding]; other site
926570007116	active site residues [active]
926570007117	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570007118	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570007119	active site
926570007120	phosphorylation site [posttranslational modification]
926570007121	dimerization interface [polypeptide binding]; other site
926570007122	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570007123	DNA binding site [nucleotide binding]
926570007124	hopanoid biosynthesis associated radical SAM protein HpnH; Region: HpnH; TIGR03470
926570007125	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570007126	FeS/SAM binding site; other site
926570007127	Domain of unknown function (DUF3463); Region: DUF3463; pfam11946
926570007128	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
926570007129	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
926570007130	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
926570007131	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
926570007132	TPP-binding site; other site
926570007133	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
926570007134	PYR/PP interface [polypeptide binding]; other site
926570007135	dimer interface [polypeptide binding]; other site
926570007136	TPP binding site [chemical binding]; other site
926570007137	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926570007138	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; cl01074
926570007139	hopanoid biosynthesis associated glycosyl transferase protein HpnI; Region: HpnI; TIGR03472
926570007140	Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520
926570007141	ligand binding site; other site
926570007142	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
926570007143	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
926570007144	B12 binding site [chemical binding]; other site
926570007145	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570007146	FeS/SAM binding site; other site
926570007147	hopanoid biosynthesis associated protein HpnK and similar proteins; Region: YdjC_HpnK_like; cd10804
926570007148	putative active site [active]
926570007149	YdjC motif; other site
926570007150	Mg binding site [ion binding]; other site
926570007151	putative homodimer interface [polypeptide binding]; other site
926570007152	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
926570007153	Ferredoxin [Energy production and conversion]; Region: COG1146
926570007154	4Fe-4S binding domain; Region: Fer4; cl02805
926570007155	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
926570007156	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
926570007157	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
926570007158	Hemerythrin-like domain; Region: Hr-like; cd12108
926570007159	Fe binding site [ion binding]; other site
926570007160	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
926570007161	apolar tunnel; other site
926570007162	heme binding site [chemical binding]; other site
926570007163	dimerization interface [polypeptide binding]; other site
926570007164	Transcriptional regulator; Region: Rrf2; cl17282
926570007165	Rrf2 family protein; Region: rrf2_super; TIGR00738
926570007166	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
926570007167	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
926570007168	ATP binding site [chemical binding]; other site
926570007169	putative Mg++ binding site [ion binding]; other site
926570007170	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570007171	nucleotide binding region [chemical binding]; other site
926570007172	ATP-binding site [chemical binding]; other site
926570007173	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
926570007174	RNA binding site [nucleotide binding]; other site
926570007175	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
926570007176	Coenzyme A transferase; Region: CoA_trans; cl17247
926570007177	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
926570007178	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926570007179	dimer interface [polypeptide binding]; other site
926570007180	active site
926570007181	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
926570007182	active site
926570007183	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
926570007184	protocatechuate 3,4-dioxygenase, beta subunit; Region: protocat_beta; TIGR02422
926570007185	active site
926570007186	4-hydroxybenzoate 3-monooxygenase; Validated; Region: PRK08243
926570007187	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
926570007188	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
926570007189	dimer interface [polypeptide binding]; other site
926570007190	active site
926570007191	heme binding site [chemical binding]; other site
926570007192	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
926570007193	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570007194	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570007195	TM-ABC transporter signature motif; other site
926570007196	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_2; cd06310
926570007197	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570007198	putative ligand binding site [chemical binding]; other site
926570007199	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570007200	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570007201	Walker A/P-loop; other site
926570007202	ATP binding site [chemical binding]; other site
926570007203	Q-loop/lid; other site
926570007204	ABC transporter signature motif; other site
926570007205	Walker B; other site
926570007206	D-loop; other site
926570007207	H-loop/switch region; other site
926570007208	short chain dehydrogenase; Provisional; Region: PRK08628
926570007209	classical (c) SDRs; Region: SDR_c; cd05233
926570007210	NAD(P) binding site [chemical binding]; other site
926570007211	active site
926570007212	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
926570007213	Amidohydrolase; Region: Amidohydro_2; pfam04909
926570007214	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926570007215	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926570007216	substrate binding site [chemical binding]; other site
926570007217	ATP binding site [chemical binding]; other site
926570007218	mannonate dehydratase; Provisional; Region: PRK03906
926570007219	mannonate dehydratase; Region: uxuA; TIGR00695
926570007220	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
926570007221	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
926570007222	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
926570007223	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570007224	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926570007225	NAD(P) binding site [chemical binding]; other site
926570007226	active site
926570007227	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570007228	Transcriptional regulators [Transcription]; Region: GntR; COG1802
926570007229	DNA-binding site [nucleotide binding]; DNA binding site
926570007230	FCD domain; Region: FCD; pfam07729
926570007231	galactarate dehydratase; Region: galactar-dH20; TIGR03248
926570007232	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
926570007233	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
926570007234	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570007235	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926570007236	Walker A/P-loop; other site
926570007237	ATP binding site [chemical binding]; other site
926570007238	Q-loop/lid; other site
926570007239	ABC transporter signature motif; other site
926570007240	Walker B; other site
926570007241	D-loop; other site
926570007242	H-loop/switch region; other site
926570007243	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926570007244	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926570007245	TM-ABC transporter signature motif; other site
926570007246	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570007247	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926570007248	Walker A/P-loop; other site
926570007249	ATP binding site [chemical binding]; other site
926570007250	Q-loop/lid; other site
926570007251	ABC transporter signature motif; other site
926570007252	Walker B; other site
926570007253	D-loop; other site
926570007254	H-loop/switch region; other site
926570007255	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926570007256	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570007257	TM-ABC transporter signature motif; other site
926570007258	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926570007259	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
926570007260	ligand binding site [chemical binding]; other site
926570007261	AAA domain; Region: AAA_26; pfam13500
926570007262	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
926570007263	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
926570007264	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
926570007265	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570007266	catalytic residue [active]
926570007267	biotin synthase; Region: bioB; TIGR00433
926570007268	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570007269	FeS/SAM binding site; other site
926570007270	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
926570007271	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
926570007272	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926570007273	inhibitor-cofactor binding pocket; inhibition site
926570007274	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570007275	catalytic residue [active]
926570007276	CCC1-related family of proteins; Region: CCC1_like; cl00278
926570007277	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
926570007278	glutamate--cysteine ligase; Region: PLN02611
926570007279	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
926570007280	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
926570007281	UbiA prenyltransferase family; Region: UbiA; pfam01040
926570007282	Predicted methyltransferase [General function prediction only]; Region: COG3897
926570007283	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
926570007284	Iron-sulfur protein interface; other site
926570007285	proximal quinone binding site [chemical binding]; other site
926570007286	SdhD (CybS) interface [polypeptide binding]; other site
926570007287	proximal heme binding site [chemical binding]; other site
926570007288	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit-like; composed of predominantly uncharacterized bacterial proteins with similarity to the E. coli SdhD subunit. One characterized protein is the respiratory...; Region: SQR_TypeC_SdhD_like; cd03495
926570007289	putative SdhC subunit interface [polypeptide binding]; other site
926570007290	putative proximal heme binding site [chemical binding]; other site
926570007291	putative Iron-sulfur protein interface [polypeptide binding]; other site
926570007292	putative proximal quinone binding site; other site
926570007293	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
926570007294	L-aspartate oxidase; Provisional; Region: PRK06175
926570007295	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
926570007296	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
926570007297	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
926570007298	Sensor N-terminal transmembrane domain; Region: Sensor_TM1; pfam13755
926570007299	Stimulus-sensing domain; Region: Stimulus_sens_1; pfam13756
926570007300	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926570007301	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570007302	dimer interface [polypeptide binding]; other site
926570007303	phosphorylation site [posttranslational modification]
926570007304	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570007305	ATP binding site [chemical binding]; other site
926570007306	Mg2+ binding site [ion binding]; other site
926570007307	G-X-G motif; other site
926570007308	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570007309	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570007310	active site
926570007311	phosphorylation site [posttranslational modification]
926570007312	intermolecular recognition site; other site
926570007313	dimerization interface [polypeptide binding]; other site
926570007314	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570007315	DNA binding site [nucleotide binding]
926570007316	Pyridoxamine 5'-phosphate oxidase; Region: Pyrid_oxidase_2; pfam13883
926570007317	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
926570007318	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
926570007319	active site
926570007320	substrate-binding site [chemical binding]; other site
926570007321	metal-binding site [ion binding]
926570007322	ATP binding site [chemical binding]; other site
926570007323	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
926570007324	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
926570007325	metal binding site [ion binding]; metal-binding site
926570007326	putative dimer interface [polypeptide binding]; other site
926570007327	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
926570007328	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926570007329	MarR family; Region: MarR; pfam01047
926570007330	HlyD family secretion protein; Region: HlyD; pfam00529
926570007331	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926570007332	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570007333	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
926570007334	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570007335	putative substrate translocation pore; other site
926570007336	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570007337	active site
926570007338	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570007339	This family is most closely related to the GT1 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II); Region: GT1_ExpC_like; cd03818
926570007340	putative ADP-binding pocket [chemical binding]; other site
926570007341	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926570007342	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570007343	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
926570007344	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
926570007345	Sel1-like repeats; Region: SEL1; smart00671
926570007346	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
926570007347	Sel1-like repeats; Region: SEL1; smart00671
926570007348	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
926570007349	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570007350	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
926570007351	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
926570007352	putative active site [active]
926570007353	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926570007354	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570007355	Walker A/P-loop; other site
926570007356	ATP binding site [chemical binding]; other site
926570007357	Q-loop/lid; other site
926570007358	ABC transporter signature motif; other site
926570007359	Walker B; other site
926570007360	D-loop; other site
926570007361	H-loop/switch region; other site
926570007362	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
926570007363	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570007364	Coenzyme A binding pocket [chemical binding]; other site
926570007365	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
926570007366	flagellar motor protein MotA; Validated; Region: PRK09110
926570007367	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
926570007368	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570007369	ligand binding site [chemical binding]; other site
926570007370	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
926570007371	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
926570007372	tetramer interface [polypeptide binding]; other site
926570007373	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570007374	catalytic residue [active]
926570007375	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926570007376	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
926570007377	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570007378	active site
926570007379	Predicted membrane protein [Function unknown]; Region: COG2246
926570007380	GtrA-like protein; Region: GtrA; pfam04138
926570007381	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
926570007382	catalytic triad [active]
926570007383	dimer interface [polypeptide binding]; other site
926570007384	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
926570007385	bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and...; Region: arch_bact_SO_family_Moco; cd02109
926570007386	Moco binding site; other site
926570007387	metal coordination site [ion binding]; other site
926570007388	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
926570007389	SmpB-tmRNA interface; other site
926570007390	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
926570007391	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
926570007392	dimer interface [polypeptide binding]; other site
926570007393	active site
926570007394	catalytic residue [active]
926570007395	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570007396	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570007397	catalytic residue [active]
926570007398	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
926570007399	tetramer interfaces [polypeptide binding]; other site
926570007400	binuclear metal-binding site [ion binding]; other site
926570007401	Competence-damaged protein; Region: CinA; pfam02464
926570007402	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570007403	PAS domain; Region: PAS_9; pfam13426
926570007404	putative active site [active]
926570007405	heme pocket [chemical binding]; other site
926570007406	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570007407	Chromate transporter; Region: Chromate_transp; pfam02417
926570007408	Chromate transporter; Region: Chromate_transp; pfam02417
926570007409	PBP superfamily domain; Region: PBP_like_2; cl17296
926570007410	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
926570007411	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570007412	dimer interface [polypeptide binding]; other site
926570007413	conserved gate region; other site
926570007414	putative PBP binding loops; other site
926570007415	ABC-ATPase subunit interface; other site
926570007416	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
926570007417	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570007418	dimer interface [polypeptide binding]; other site
926570007419	conserved gate region; other site
926570007420	putative PBP binding loops; other site
926570007421	ABC-ATPase subunit interface; other site
926570007422	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
926570007423	putative deacylase active site [active]
926570007424	MAPEG family; Region: MAPEG; cl09190
926570007425	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
926570007426	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
926570007427	active site
926570007428	Zn binding site [ion binding]; other site
926570007429	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
926570007430	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
926570007431	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
926570007432	alphaNTD - beta interaction site [polypeptide binding]; other site
926570007433	alphaNTD homodimer interface [polypeptide binding]; other site
926570007434	alphaNTD - beta' interaction site [polypeptide binding]; other site
926570007435	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
926570007436	30S ribosomal protein S11; Validated; Region: PRK05309
926570007437	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
926570007438	30S ribosomal protein S13; Region: bact_S13; TIGR03631
926570007439	adenylate kinase; Reviewed; Region: adk; PRK00279
926570007440	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
926570007441	AMP-binding site [chemical binding]; other site
926570007442	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
926570007443	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
926570007444	SecY translocase; Region: SecY; pfam00344
926570007445	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
926570007446	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
926570007447	23S rRNA binding site [nucleotide binding]; other site
926570007448	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
926570007449	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
926570007450	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
926570007451	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
926570007452	5S rRNA interface [nucleotide binding]; other site
926570007453	23S rRNA interface [nucleotide binding]; other site
926570007454	L5 interface [polypeptide binding]; other site
926570007455	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
926570007456	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
926570007457	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
926570007458	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
926570007459	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
926570007460	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
926570007461	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
926570007462	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
926570007463	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
926570007464	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
926570007465	RNA binding site [nucleotide binding]; other site
926570007466	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
926570007467	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
926570007468	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
926570007469	putative translocon interaction site; other site
926570007470	23S rRNA interface [nucleotide binding]; other site
926570007471	signal recognition particle (SRP54) interaction site; other site
926570007472	L23 interface [polypeptide binding]; other site
926570007473	trigger factor interaction site; other site
926570007474	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
926570007475	23S rRNA interface [nucleotide binding]; other site
926570007476	5S rRNA interface [nucleotide binding]; other site
926570007477	putative antibiotic binding site [chemical binding]; other site
926570007478	L25 interface [polypeptide binding]; other site
926570007479	L27 interface [polypeptide binding]; other site
926570007480	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
926570007481	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
926570007482	G-X-X-G motif; other site
926570007483	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
926570007484	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
926570007485	putative translocon binding site; other site
926570007486	protein-rRNA interface [nucleotide binding]; other site
926570007487	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
926570007488	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
926570007489	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
926570007490	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
926570007491	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
926570007492	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
926570007493	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
926570007494	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
926570007495	elongation factor Tu; Reviewed; Region: PRK00049
926570007496	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
926570007497	G1 box; other site
926570007498	GEF interaction site [polypeptide binding]; other site
926570007499	GTP/Mg2+ binding site [chemical binding]; other site
926570007500	Switch I region; other site
926570007501	G2 box; other site
926570007502	G3 box; other site
926570007503	Switch II region; other site
926570007504	G4 box; other site
926570007505	G5 box; other site
926570007506	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
926570007507	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
926570007508	Antibiotic Binding Site [chemical binding]; other site
926570007509	30S ribosomal protein S7; Validated; Region: PRK05302
926570007510	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
926570007511	S17 interaction site [polypeptide binding]; other site
926570007512	S8 interaction site; other site
926570007513	16S rRNA interaction site [nucleotide binding]; other site
926570007514	streptomycin interaction site [chemical binding]; other site
926570007515	23S rRNA interaction site [nucleotide binding]; other site
926570007516	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
926570007517	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
926570007518	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
926570007519	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
926570007520	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
926570007521	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
926570007522	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
926570007523	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
926570007524	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
926570007525	DNA binding site [nucleotide binding]
926570007526	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
926570007527	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
926570007528	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
926570007529	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
926570007530	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
926570007531	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
926570007532	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
926570007533	RPB3 interaction site [polypeptide binding]; other site
926570007534	RPB1 interaction site [polypeptide binding]; other site
926570007535	RPB11 interaction site [polypeptide binding]; other site
926570007536	RPB10 interaction site [polypeptide binding]; other site
926570007537	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
926570007538	L11 interface [polypeptide binding]; other site
926570007539	putative EF-Tu interaction site [polypeptide binding]; other site
926570007540	putative EF-G interaction site [polypeptide binding]; other site
926570007541	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
926570007542	23S rRNA interface [nucleotide binding]; other site
926570007543	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
926570007544	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
926570007545	mRNA/rRNA interface [nucleotide binding]; other site
926570007546	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
926570007547	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
926570007548	23S rRNA interface [nucleotide binding]; other site
926570007549	L7/L12 interface [polypeptide binding]; other site
926570007550	putative thiostrepton binding site; other site
926570007551	L25 interface [polypeptide binding]; other site
926570007552	Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047
926570007553	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926570007554	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926570007555	active site
926570007556	catalytic tetrad [active]
926570007557	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
926570007558	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
926570007559	HIGH motif; other site
926570007560	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
926570007561	active site
926570007562	KMSKS motif; other site
926570007563	HAD-superfamily class IIA hydrolase, TIGR01459; Region: HAD-SF-IIA-hyp4
926570007564	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570007565	active site
926570007566	motif I; other site
926570007567	motif II; other site
926570007568	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570007569	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
926570007570	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
926570007571	quinone interaction residues [chemical binding]; other site
926570007572	active site
926570007573	catalytic residues [active]
926570007574	FMN binding site [chemical binding]; other site
926570007575	substrate binding site [chemical binding]; other site
926570007576	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
926570007577	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
926570007578	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
926570007579	beta alanine--pyruvate transaminase; Provisional; Region: PRK09221
926570007580	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926570007581	inhibitor-cofactor binding pocket; inhibition site
926570007582	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570007583	catalytic residue [active]
926570007584	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
926570007585	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
926570007586	tetramerization interface [polypeptide binding]; other site
926570007587	NAD(P) binding site [chemical binding]; other site
926570007588	catalytic residues [active]
926570007589	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
926570007590	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
926570007591	tandem repeat interface [polypeptide binding]; other site
926570007592	oligomer interface [polypeptide binding]; other site
926570007593	active site residues [active]
926570007594	Protein of unknown function (DUF1489); Region: DUF1489; pfam07370
926570007595	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570007596	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570007597	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570007598	ChrR Cupin-like domain; Region: Cupin_7; pfam12973
926570007599	ChrR Cupin-like domain; Region: Cupin_7; pfam12973
926570007600	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570007601	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570007602	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570007603	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570007604	TM-ABC transporter signature motif; other site
926570007605	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570007606	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570007607	Walker A/P-loop; other site
926570007608	ATP binding site [chemical binding]; other site
926570007609	Q-loop/lid; other site
926570007610	ABC transporter signature motif; other site
926570007611	Walker B; other site
926570007612	D-loop; other site
926570007613	H-loop/switch region; other site
926570007614	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
926570007615	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
926570007616	putative ligand binding site [chemical binding]; other site
926570007617	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926570007618	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
926570007619	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570007620	Walker A/P-loop; other site
926570007621	ATP binding site [chemical binding]; other site
926570007622	Q-loop/lid; other site
926570007623	ABC transporter signature motif; other site
926570007624	Walker B; other site
926570007625	D-loop; other site
926570007626	H-loop/switch region; other site
926570007627	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
926570007628	nudix motif; other site
926570007629	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
926570007630	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
926570007631	C-terminal domain interface [polypeptide binding]; other site
926570007632	GSH binding site (G-site) [chemical binding]; other site
926570007633	dimer interface [polypeptide binding]; other site
926570007634	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
926570007635	Moco binding site; other site
926570007636	metal coordination site [ion binding]; other site
926570007637	Cytochrome c; Region: Cytochrom_C; cl11414
926570007638	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
926570007639	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
926570007640	TrkA-N domain; Region: TrkA_N; pfam02254
926570007641	glutathione reductase; Validated; Region: PRK06116
926570007642	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570007643	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570007644	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926570007645	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
926570007646	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
926570007647	nicotinate phosphoribosyltransferase; Provisional; Region: PRK07188
926570007648	active site
926570007649	Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528
926570007650	NAD synthetase; Provisional; Region: PRK13981
926570007651	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
926570007652	multimer interface [polypeptide binding]; other site
926570007653	active site
926570007654	catalytic triad [active]
926570007655	protein interface 1 [polypeptide binding]; other site
926570007656	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
926570007657	homodimer interface [polypeptide binding]; other site
926570007658	NAD binding pocket [chemical binding]; other site
926570007659	ATP binding pocket [chemical binding]; other site
926570007660	Mg binding site [ion binding]; other site
926570007661	active-site loop [active]
926570007662	Hint domain; Region: Hint_2; pfam13403
926570007663	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
926570007664	IHF - DNA interface [nucleotide binding]; other site
926570007665	IHF dimer interface [polypeptide binding]; other site
926570007666	Domain of unknown function (DUF4337); Region: DUF4337; pfam14235
926570007667	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
926570007668	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
926570007669	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
926570007670	Switch I; other site
926570007671	Switch II; other site
926570007672	septum formation inhibitor; Reviewed; Region: minC; PRK05177
926570007673	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
926570007674	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
926570007675	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570007676	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570007677	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
926570007678	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
926570007679	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
926570007680	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
926570007681	Protein export membrane protein; Region: SecD_SecF; pfam02355
926570007682	Protein of unknown function (DUF3775); Region: DUF3775; pfam12616
926570007683	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
926570007684	active site
926570007685	catalytic triad [active]
926570007686	oxyanion hole [active]
926570007687	OpgC protein; Region: OpgC_C; pfam10129
926570007688	recombination protein RecR; Reviewed; Region: recR; PRK00076
926570007689	RecR protein; Region: RecR; pfam02132
926570007690	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
926570007691	putative active site [active]
926570007692	putative metal-binding site [ion binding]; other site
926570007693	tetramer interface [polypeptide binding]; other site
926570007694	hypothetical protein; Validated; Region: PRK00153
926570007695	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
926570007696	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570007697	Walker A motif; other site
926570007698	ATP binding site [chemical binding]; other site
926570007699	Walker B motif; other site
926570007700	arginine finger; other site
926570007701	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
926570007702	DNA polymerase III gamma and tau subunits C terminal; Region: DUF3646; pfam12362
926570007703	NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding [DNA replication, recombination, and repair]; Region: NPY1; COG2816
926570007704	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
926570007705	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
926570007706	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
926570007707	putative NADH binding site [chemical binding]; other site
926570007708	putative active site [active]
926570007709	nudix motif; other site
926570007710	putative metal binding site [ion binding]; other site
926570007711	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
926570007712	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
926570007713	Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain; Region: MPP_ACP5; cd07378
926570007714	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926570007715	active site
926570007716	metal binding site [ion binding]; metal-binding site
926570007717	Protein of unknown function (DUF1355); Region: DUF1355; cl17712
926570007718	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
926570007719	Protein of unknown function DUF58; Region: DUF58; pfam01882
926570007720	MoxR-like ATPases [General function prediction only]; Region: COG0714
926570007721	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570007722	Walker A motif; other site
926570007723	ATP binding site [chemical binding]; other site
926570007724	Walker B motif; other site
926570007725	arginine finger; other site
926570007726	Protein of unknown function (DUF1285); Region: DUF1285; pfam06938
926570007727	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
926570007728	putative active site [active]
926570007729	putative CoA binding site [chemical binding]; other site
926570007730	nudix motif; other site
926570007731	metal binding site [ion binding]; metal-binding site
926570007732	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
926570007733	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
926570007734	active site
926570007735	NTP binding site [chemical binding]; other site
926570007736	metal binding triad [ion binding]; metal-binding site
926570007737	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
926570007738	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
926570007739	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570007740	S-adenosylmethionine binding site [chemical binding]; other site
926570007741	exopolyphosphatase; Region: exo_poly_only; TIGR03706
926570007742	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
926570007743	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926570007744	TPP-binding site [chemical binding]; other site
926570007745	Transketolase, pyrimidine binding domain; Region: Transket_pyr; smart00861
926570007746	PYR/PP interface [polypeptide binding]; other site
926570007747	dimer interface [polypeptide binding]; other site
926570007748	TPP binding site [chemical binding]; other site
926570007749	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
926570007750	30S subunit binding site; other site
926570007751	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
926570007752	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
926570007753	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
926570007754	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
926570007755	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
926570007756	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
926570007757	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
926570007758	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
926570007759	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
926570007760	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
926570007761	ATP binding site [chemical binding]; other site
926570007762	Walker A motif; other site
926570007763	hexamer interface [polypeptide binding]; other site
926570007764	Walker B motif; other site
926570007765	Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion]; Region: CpaE; COG4963
926570007766	Flp pilus assembly protein CpaB [Intracellular trafficking and secretion]; Region: CpaB; COG3745
926570007767	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
926570007768	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
926570007769	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926570007770	substrate binding site [chemical binding]; other site
926570007771	ATP binding site [chemical binding]; other site
926570007772	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
926570007773	glutathione synthetase; Provisional; Region: PRK05246
926570007774	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
926570007775	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
926570007776	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
926570007777	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
926570007778	active site
926570007779	metal binding site [ion binding]; metal-binding site
926570007780	Predicted membrane protein (DUF2177); Region: DUF2177; pfam09945
926570007781	isocitrate dehydrogenase; Validated; Region: PRK09222
926570007782	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
926570007783	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570007784	putative substrate translocation pore; other site
926570007785	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
926570007786	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
926570007787	homotrimer interaction site [polypeptide binding]; other site
926570007788	zinc binding site [ion binding]; other site
926570007789	CDP-binding sites; other site
926570007790	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
926570007791	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
926570007792	FMN binding site [chemical binding]; other site
926570007793	active site
926570007794	catalytic residues [active]
926570007795	substrate binding site [chemical binding]; other site
926570007796	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
926570007797	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926570007798	putative active site [active]
926570007799	heme pocket [chemical binding]; other site
926570007800	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570007801	dimer interface [polypeptide binding]; other site
926570007802	phosphorylation site [posttranslational modification]
926570007803	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570007804	ATP binding site [chemical binding]; other site
926570007805	Mg2+ binding site [ion binding]; other site
926570007806	G-X-G motif; other site
926570007807	nitrogen regulation protein NR(I); Region: ntrC; TIGR01818
926570007808	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570007809	active site
926570007810	phosphorylation site [posttranslational modification]
926570007811	intermolecular recognition site; other site
926570007812	dimerization interface [polypeptide binding]; other site
926570007813	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570007814	Walker A motif; other site
926570007815	ATP binding site [chemical binding]; other site
926570007816	Walker B motif; other site
926570007817	arginine finger; other site
926570007818	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
926570007819	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000
926570007820	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926570007821	dimerization interface [polypeptide binding]; other site
926570007822	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570007823	dimer interface [polypeptide binding]; other site
926570007824	phosphorylation site [posttranslational modification]
926570007825	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570007826	ATP binding site [chemical binding]; other site
926570007827	Mg2+ binding site [ion binding]; other site
926570007828	G-X-G motif; other site
926570007829	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
926570007830	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570007831	active site
926570007832	phosphorylation site [posttranslational modification]
926570007833	intermolecular recognition site; other site
926570007834	dimerization interface [polypeptide binding]; other site
926570007835	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570007836	Walker A motif; other site
926570007837	ATP binding site [chemical binding]; other site
926570007838	Walker B motif; other site
926570007839	arginine finger; other site
926570007840	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570007841	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
926570007842	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
926570007843	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
926570007844	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
926570007845	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
926570007846	dimer interface [polypeptide binding]; other site
926570007847	ssDNA binding site [nucleotide binding]; other site
926570007848	tetramer (dimer of dimers) interface [polypeptide binding]; other site
926570007849	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
926570007850	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
926570007851	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
926570007852	Predicted transcriptional regulators [Transcription]; Region: COG1510
926570007853	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570007854	dimerization interface [polypeptide binding]; other site
926570007855	putative DNA binding site [nucleotide binding]; other site
926570007856	putative Zn2+ binding site [ion binding]; other site
926570007857	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
926570007858	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570007859	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570007860	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
926570007861	putative effector binding pocket; other site
926570007862	dimerization interface [polypeptide binding]; other site
926570007863	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
926570007864	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
926570007865	putative molybdopterin cofactor binding site [chemical binding]; other site
926570007866	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
926570007867	putative molybdopterin cofactor binding site; other site
926570007868	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570007869	Methyltransferase domain; Region: Methyltransf_11; pfam08241
926570007870	S-adenosylmethionine binding site [chemical binding]; other site
926570007871	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
926570007872	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
926570007873	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
926570007874	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
926570007875	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK06585
926570007876	Lipopolysaccharide-assembly; Region: LptE; cl01125
926570007877	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
926570007878	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
926570007879	HIGH motif; other site
926570007880	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
926570007881	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
926570007882	active site
926570007883	KMSKS motif; other site
926570007884	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
926570007885	tRNA binding surface [nucleotide binding]; other site
926570007886	Domain of unknown function (DUF3576); Region: DUF3576; pfam12100
926570007887	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
926570007888	Thiamine monophosphate synthase/TENI; Region: TMP-TENI; cl17228
926570007889	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
926570007890	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926570007891	catalytic residue [active]
926570007892	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
926570007893	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926570007894	NAD binding site [chemical binding]; other site
926570007895	Protein of unknown function (DUF445); Region: DUF445; pfam04286
926570007896	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
926570007897	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
926570007898	active site
926570007899	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2187
926570007900	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
926570007901	Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; Region: PrsA; COG0462
926570007902	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570007903	active site
926570007904	Uncharacterized ACR, YagE family COG1723; Region: DUF155; pfam02582
926570007905	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
926570007906	Uncharacterized conserved protein (DUF2267); Region: DUF2267; pfam10025
926570007907	Patatin-like phospholipase; Region: Patatin; pfam01734
926570007908	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570007909	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570007910	putative substrate translocation pore; other site
926570007911	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570007912	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926570007913	TPP-binding site [chemical binding]; other site
926570007914	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
926570007915	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
926570007916	PYR/PP interface [polypeptide binding]; other site
926570007917	dimer interface [polypeptide binding]; other site
926570007918	TPP binding site [chemical binding]; other site
926570007919	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926570007920	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570007921	putative DNA binding site [nucleotide binding]; other site
926570007922	putative Zn2+ binding site [ion binding]; other site
926570007923	AsnC family; Region: AsnC_trans_reg; pfam01037
926570007924	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570007925	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570007926	metal binding site [ion binding]; metal-binding site
926570007927	active site
926570007928	I-site; other site
926570007929	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570007930	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570007931	D-galactonate transporter; Region: 2A0114; TIGR00893
926570007932	putative substrate translocation pore; other site
926570007933	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
926570007934	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
926570007935	[2Fe-2S] cluster binding site [ion binding]; other site
926570007936	C-terminal catalytic domain of GbcA (glycine betaine catabolism A) from Pseudomonas aeruginosa PAO1 and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_GbcA-like; cd08884
926570007937	putative alpha subunit interface [polypeptide binding]; other site
926570007938	putative active site [active]
926570007939	putative substrate binding site [chemical binding]; other site
926570007940	Fe binding site [ion binding]; other site
926570007941	methionine gamma-lyase; Validated; Region: PRK07049
926570007942	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
926570007943	homodimer interface [polypeptide binding]; other site
926570007944	substrate-cofactor binding pocket; other site
926570007945	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570007946	catalytic residue [active]
926570007947	sarcosine oxidase, alpha subunit family, heterotetrameric form; Region: soxA; TIGR01372
926570007948	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926570007949	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926570007950	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
926570007951	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926570007952	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
926570007953	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570007954	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570007955	dimerization interface [polypeptide binding]; other site
926570007956	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
926570007957	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926570007958	Walker A/P-loop; other site
926570007959	ATP binding site [chemical binding]; other site
926570007960	Q-loop/lid; other site
926570007961	ABC transporter signature motif; other site
926570007962	Walker B; other site
926570007963	D-loop; other site
926570007964	H-loop/switch region; other site
926570007965	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926570007966	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926570007967	Walker A/P-loop; other site
926570007968	ATP binding site [chemical binding]; other site
926570007969	Q-loop/lid; other site
926570007970	ABC transporter signature motif; other site
926570007971	Walker B; other site
926570007972	D-loop; other site
926570007973	H-loop/switch region; other site
926570007974	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926570007975	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926570007976	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570007977	dimer interface [polypeptide binding]; other site
926570007978	conserved gate region; other site
926570007979	putative PBP binding loops; other site
926570007980	ABC-ATPase subunit interface; other site
926570007981	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926570007982	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570007983	dimer interface [polypeptide binding]; other site
926570007984	conserved gate region; other site
926570007985	putative PBP binding loops; other site
926570007986	ABC-ATPase subunit interface; other site
926570007987	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926570007988	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926570007989	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570007990	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926570007991	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926570007992	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926570007993	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926570007994	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
926570007995	putative acyl-acceptor binding pocket; other site
926570007996	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
926570007997	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
926570007998	Paraquat-inducible protein A; Region: PqiA; pfam04403
926570007999	Paraquat-inducible protein A; Region: PqiA; pfam04403
926570008000	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
926570008001	mce related protein; Region: MCE; pfam02470
926570008002	mce related protein; Region: MCE; pfam02470
926570008003	Protein of unknown function (DUF330); Region: DUF330; pfam03886
926570008004	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
926570008005	active site
926570008006	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; pfam09867
926570008007	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
926570008008	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
926570008009	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
926570008010	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
926570008011	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
926570008012	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570008013	ligand binding site [chemical binding]; other site
926570008014	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
926570008015	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
926570008016	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
926570008017	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
926570008018	phosphopeptide binding site; other site
926570008019	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
926570008020	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
926570008021	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
926570008022	Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715
926570008023	Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715
926570008024	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
926570008025	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
926570008026	Surface antigen; Region: Bac_surface_Ag; pfam01103
926570008027	haemagglutination activity domain; Region: Haemagg_act; pfam05860
926570008028	CHAT domain; Region: CHAT; pfam12770
926570008029	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
926570008030	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
926570008031	active site
926570008032	ATP binding site [chemical binding]; other site
926570008033	substrate binding site [chemical binding]; other site
926570008034	activation loop (A-loop); other site
926570008035	Domain of unknown function (DUF4384); Region: DUF4384; pfam14326
926570008036	Cytochrome c; Region: Cytochrom_C; cl11414
926570008037	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
926570008038	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
926570008039	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570008040	ATP binding site [chemical binding]; other site
926570008041	putative Mg++ binding site [ion binding]; other site
926570008042	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570008043	nucleotide binding region [chemical binding]; other site
926570008044	ATP-binding site [chemical binding]; other site
926570008045	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
926570008046	HRDC domain; Region: HRDC; pfam00570
926570008047	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926570008048	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926570008049	ligand binding site [chemical binding]; other site
926570008050	flexible hinge region; other site
926570008051	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
926570008052	non-specific DNA interactions [nucleotide binding]; other site
926570008053	DNA binding site [nucleotide binding]
926570008054	sequence specific DNA binding site [nucleotide binding]; other site
926570008055	putative cAMP binding site [chemical binding]; other site
926570008056	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
926570008057	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
926570008058	homodimer interface [polypeptide binding]; other site
926570008059	substrate-cofactor binding pocket; other site
926570008060	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570008061	catalytic residue [active]
926570008062	aminopeptidase N; Provisional; Region: pepN; PRK14015
926570008063	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
926570008064	Zn binding site [ion binding]; other site
926570008065	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
926570008066	Protein of unknown function, DUF482; Region: DUF482; pfam04339
926570008067	CsbD-like; Region: CsbD; pfam05532
926570008068	Amino acid permease; Region: AA_permease_2; pfam13520
926570008069	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxase_2; pfam12766
926570008070	PPOX class probable FMN-dependent enzyme, alr4036 family; Region: PPOX_FMN_cyano; TIGR04026
926570008071	putative glutathione S-transferase; Provisional; Region: PRK10357
926570008072	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
926570008073	putative C-terminal domain interface [polypeptide binding]; other site
926570008074	putative GSH binding site (G-site) [chemical binding]; other site
926570008075	putative dimer interface [polypeptide binding]; other site
926570008076	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
926570008077	dimer interface [polypeptide binding]; other site
926570008078	N-terminal domain interface [polypeptide binding]; other site
926570008079	putative substrate binding pocket (H-site) [chemical binding]; other site
926570008080	Phosphotransferase enzyme family; Region: APH; pfam01636
926570008081	Acyl-CoA dehydrogenase (ACAD) 10 and 11, N-terminal domain, and similar proteins. This subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: ACAD10_11_like; cd05154
926570008082	putative active site [active]
926570008083	putative substrate binding site [chemical binding]; other site
926570008084	ATP binding site [chemical binding]; other site
926570008085	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570008086	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570008087	active site
926570008088	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
926570008089	Quinone oxidoreductase (QOR); Region: QOR1; cd08241
926570008090	NAD(P) binding site [chemical binding]; other site
926570008091	hypothetical protein; Provisional; Region: PRK06194
926570008092	classical (c) SDRs; Region: SDR_c; cd05233
926570008093	NAD(P) binding site [chemical binding]; other site
926570008094	active site
926570008095	thiamine monophosphate kinase; Provisional; Region: PRK05731
926570008096	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
926570008097	ATP binding site [chemical binding]; other site
926570008098	dimerization interface [polypeptide binding]; other site
926570008099	transcription antitermination factor NusB; Region: nusB; TIGR01951
926570008100	putative RNA binding site [nucleotide binding]; other site
926570008101	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
926570008102	homopentamer interface [polypeptide binding]; other site
926570008103	active site
926570008104	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Provisional; Region: PRK14019
926570008105	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
926570008106	GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925
926570008107	dimerization interface [polypeptide binding]; other site
926570008108	active site
926570008109	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
926570008110	Lumazine binding domain; Region: Lum_binding; pfam00677
926570008111	Lumazine binding domain; Region: Lum_binding; pfam00677
926570008112	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
926570008113	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
926570008114	catalytic motif [active]
926570008115	Zn binding site [ion binding]; other site
926570008116	RibD C-terminal domain; Region: RibD_C; cl17279
926570008117	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
926570008118	ATP cone domain; Region: ATP-cone; pfam03477
926570008119	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
926570008120	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
926570008121	dimer interface [polypeptide binding]; other site
926570008122	active site
926570008123	glycine-pyridoxal phosphate binding site [chemical binding]; other site
926570008124	folate binding site [chemical binding]; other site
926570008125	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
926570008126	Uncharacterized conserved protein [Function unknown]; Region: COG2835
926570008127	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3536
926570008128	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
926570008129	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570008130	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
926570008131	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
926570008132	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
926570008133	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
926570008134	Bacterial export proteins, family 3; Region: Bac_export_3; pfam01313
926570008135	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
926570008136	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
926570008137	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
926570008138	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
926570008139	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK06004
926570008140	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
926570008141	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926570008142	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570008143	ATP binding site [chemical binding]; other site
926570008144	Mg2+ binding site [ion binding]; other site
926570008145	G-X-G motif; other site
926570008146	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
926570008147	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
926570008148	active site
926570008149	nucleophile elbow; other site
926570008150	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
926570008151	Ribonuclease P; Region: Ribonuclease_P; pfam00825
926570008152	Haemolytic domain; Region: Haemolytic; pfam01809
926570008153	membrane protein insertase; Provisional; Region: PRK01318
926570008154	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
926570008155	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
926570008156	G1 box; other site
926570008157	GTP/Mg2+ binding site [chemical binding]; other site
926570008158	Switch I region; other site
926570008159	G2 box; other site
926570008160	G3 box; other site
926570008161	Switch II region; other site
926570008162	G4 box; other site
926570008163	G5 box; other site
926570008164	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
926570008165	feedback inhibition sensing region; other site
926570008166	homohexameric interface [polypeptide binding]; other site
926570008167	nucleotide binding site [chemical binding]; other site
926570008168	N-acetyl-L-glutamate binding site [chemical binding]; other site
926570008169	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570008170	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570008171	dimer interface [polypeptide binding]; other site
926570008172	putative CheW interface [polypeptide binding]; other site
926570008173	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
926570008174	Domain of unknown function DUF21; Region: DUF21; pfam01595
926570008175	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
926570008176	Transporter associated domain; Region: CorC_HlyC; smart01091
926570008177	Exo-beta-1,3-glucanase [Carbohydrate transport and metabolism]; Region: COG5309
926570008178	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926570008179	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570008180	active site
926570008181	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
926570008182	tartrate dehydrogenase; Region: TTC; TIGR02089
926570008183	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
926570008184	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
926570008185	substrate binding site [chemical binding]; other site
926570008186	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
926570008187	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
926570008188	substrate binding site [chemical binding]; other site
926570008189	ligand binding site [chemical binding]; other site
926570008190	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
926570008191	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
926570008192	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
926570008193	RimM N-terminal domain; Region: RimM; pfam01782
926570008194	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
926570008195	signal recognition particle protein; Provisional; Region: PRK10867
926570008196	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
926570008197	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
926570008198	P loop; other site
926570008199	GTP binding site [chemical binding]; other site
926570008200	Signal peptide binding domain; Region: SRP_SPB; pfam02978
926570008201	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
926570008202	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
926570008203	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
926570008204	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
926570008205	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
926570008206	ligand binding site [chemical binding]; other site
926570008207	homodimer interface [polypeptide binding]; other site
926570008208	NAD(P) binding site [chemical binding]; other site
926570008209	trimer interface B [polypeptide binding]; other site
926570008210	trimer interface A [polypeptide binding]; other site
926570008211	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
926570008212	Clp protease; Region: CLP_protease; pfam00574
926570008213	oligomer interface [polypeptide binding]; other site
926570008214	active site residues [active]
926570008215	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
926570008216	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570008217	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
926570008218	putative dimerization interface [polypeptide binding]; other site
926570008219	Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821
926570008220	putative hydrophobic ligand binding site [chemical binding]; other site
926570008221	protein interface [polypeptide binding]; other site
926570008222	gate; other site
926570008223	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
926570008224	DNA-binding site [nucleotide binding]; DNA binding site
926570008225	Transcriptional regulators [Transcription]; Region: FadR; COG2186
926570008226	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
926570008227	DNA-binding site [nucleotide binding]; DNA binding site
926570008228	FCD domain; Region: FCD; pfam07729
926570008229	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
926570008230	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570008231	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570008232	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570008233	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
926570008234	Zn binding site [ion binding]; other site
926570008235	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
926570008236	Cytochrome c oxidase subunit III.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665
926570008237	Subunit III/VIIa interface [polypeptide binding]; other site
926570008238	Phospholipid binding site [chemical binding]; other site
926570008239	Subunit I/III interface [polypeptide binding]; other site
926570008240	Subunit III/VIb interface [polypeptide binding]; other site
926570008241	Subunit III/VIa interface; other site
926570008242	Subunit III/Vb interface [polypeptide binding]; other site
926570008243	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
926570008244	UbiA prenyltransferase family; Region: UbiA; pfam01040
926570008245	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
926570008246	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
926570008247	Subunit I/III interface [polypeptide binding]; other site
926570008248	D-pathway; other site
926570008249	Subunit I/VIIc interface [polypeptide binding]; other site
926570008250	Subunit I/IV interface [polypeptide binding]; other site
926570008251	Subunit I/II interface [polypeptide binding]; other site
926570008252	Low-spin heme (heme a) binding site [chemical binding]; other site
926570008253	Subunit I/VIIa interface [polypeptide binding]; other site
926570008254	Subunit I/VIa interface [polypeptide binding]; other site
926570008255	Dimer interface; other site
926570008256	Putative water exit pathway; other site
926570008257	Binuclear center (heme a3/CuB) [ion binding]; other site
926570008258	K-pathway; other site
926570008259	Subunit I/Vb interface [polypeptide binding]; other site
926570008260	Putative proton exit pathway; other site
926570008261	Subunit I/VIb interface; other site
926570008262	Subunit I/VIc interface [polypeptide binding]; other site
926570008263	Electron transfer pathway; other site
926570008264	Subunit I/VIIIb interface [polypeptide binding]; other site
926570008265	Subunit I/VIIb interface [polypeptide binding]; other site
926570008266	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
926570008267	cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00140
926570008268	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
926570008269	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570008270	GcrA cell cycle regulator; Region: GcrA; cl11564
926570008271	Bacterial SH3 domain; Region: SH3_4; pfam06347
926570008272	Bacterial SH3 domain; Region: SH3_4; pfam06347
926570008273	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
926570008274	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
926570008275	ATP binding site [chemical binding]; other site
926570008276	substrate interface [chemical binding]; other site
926570008277	Predicted PP-loop superfamily ATPase [General function prediction only]; Region: COG0603
926570008278	Ligand Binding Site [chemical binding]; other site
926570008279	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
926570008280	FMN binding site [chemical binding]; other site
926570008281	substrate binding site [chemical binding]; other site
926570008282	putative catalytic residue [active]
926570008283	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570008284	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570008285	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570008286	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
926570008287	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570008288	catalytic loop [active]
926570008289	iron binding site [ion binding]; other site
926570008290	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926570008291	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
926570008292	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570008293	metabolite-proton symporter; Region: 2A0106; TIGR00883
926570008294	putative substrate translocation pore; other site
926570008295	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926570008296	dimer interface [polypeptide binding]; other site
926570008297	phosphorylation site [posttranslational modification]
926570008298	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570008299	ATP binding site [chemical binding]; other site
926570008300	Mg2+ binding site [ion binding]; other site
926570008301	G-X-G motif; other site
926570008302	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570008303	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570008304	active site
926570008305	phosphorylation site [posttranslational modification]
926570008306	intermolecular recognition site; other site
926570008307	dimerization interface [polypeptide binding]; other site
926570008308	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570008309	DNA binding site [nucleotide binding]
926570008310	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase; Region: PLPDE_III_ODC; cd00622
926570008311	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
926570008312	dimer interface [polypeptide binding]; other site
926570008313	active site
926570008314	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926570008315	catalytic residues [active]
926570008316	substrate binding site [chemical binding]; other site
926570008317	Dienelactone hydrolase family; Region: DLH; pfam01738
926570008318	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926570008319	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926570008320	Probable Catalytic site; other site
926570008321	metal-binding site
926570008322	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
926570008323	pyruvate phosphate dikinase; Provisional; Region: PRK09279
926570008324	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
926570008325	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926570008326	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926570008327	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
926570008328	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
926570008329	dimer interface [polypeptide binding]; other site
926570008330	motif 1; other site
926570008331	active site
926570008332	motif 2; other site
926570008333	motif 3; other site
926570008334	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570008335	Isovaleryl-CoA dehydrogenase; Region: IVD; cd01156
926570008336	substrate binding site [chemical binding]; other site
926570008337	FAD binding site [chemical binding]; other site
926570008338	catalytic base [active]
926570008339	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
926570008340	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; pfam03255
926570008341	spermidine synthase; Provisional; Region: PRK00811
926570008342	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926570008343	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570008344	S-adenosylmethionine binding site [chemical binding]; other site
926570008345	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; pfam02675
926570008346	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926570008347	This family is most closely related to the GT1 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core; Region: GT1_WavL_like; cd03819
926570008348	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
926570008349	putative ADP-binding pocket [chemical binding]; other site
926570008350	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570008351	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
926570008352	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
926570008353	putative active site [active]
926570008354	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
926570008355	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
926570008356	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
926570008357	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
926570008358	active site
926570008359	dimer interface [polypeptide binding]; other site
926570008360	motif 1; other site
926570008361	motif 2; other site
926570008362	motif 3; other site
926570008363	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
926570008364	anticodon binding site; other site
926570008365	beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431
926570008366	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
926570008367	Bacterial transcriptional regulator; Region: IclR; pfam01614
926570008368	OsmC-like protein; Region: OsmC; pfam02566
926570008369	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570008370	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926570008371	Walker A/P-loop; other site
926570008372	ATP binding site [chemical binding]; other site
926570008373	Q-loop/lid; other site
926570008374	ABC transporter signature motif; other site
926570008375	Walker B; other site
926570008376	D-loop; other site
926570008377	H-loop/switch region; other site
926570008378	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570008379	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926570008380	Walker A/P-loop; other site
926570008381	ATP binding site [chemical binding]; other site
926570008382	Q-loop/lid; other site
926570008383	ABC transporter signature motif; other site
926570008384	Walker B; other site
926570008385	D-loop; other site
926570008386	H-loop/switch region; other site
926570008387	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926570008388	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926570008389	TM-ABC transporter signature motif; other site
926570008390	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570008391	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926570008392	TM-ABC transporter signature motif; other site
926570008393	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926570008394	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926570008395	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570008396	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570008397	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
926570008398	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
926570008399	THF binding site; other site
926570008400	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
926570008401	substrate binding site [chemical binding]; other site
926570008402	THF binding site; other site
926570008403	zinc-binding site [ion binding]; other site
926570008404	major facilitator superfamily transporter; Provisional; Region: PRK05122
926570008405	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570008406	dihydroxy-acid dehydratase; Validated; Region: PRK06131
926570008407	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570008408	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570008409	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570008410	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570008411	active site
926570008412	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570008413	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570008414	TM-ABC transporter signature motif; other site
926570008415	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570008416	TM-ABC transporter signature motif; other site
926570008417	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570008418	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570008419	Walker A/P-loop; other site
926570008420	ATP binding site [chemical binding]; other site
926570008421	Q-loop/lid; other site
926570008422	ABC transporter signature motif; other site
926570008423	Walker B; other site
926570008424	D-loop; other site
926570008425	H-loop/switch region; other site
926570008426	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570008427	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
926570008428	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
926570008429	putative ligand binding site [chemical binding]; other site
926570008430	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
926570008431	Predicted transcriptional regulators [Transcription]; Region: COG1695
926570008432	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
926570008433	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
926570008434	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; cl17722
926570008435	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570008436	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
926570008437	CcdB protein; Region: CcdB; cl03380
926570008438	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570008439	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570008440	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
926570008441	putative effector binding pocket; other site
926570008442	putative dimerization interface [polypeptide binding]; other site
926570008443	short chain dehydrogenase; Provisional; Region: PRK12939
926570008444	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570008445	NAD(P) binding site [chemical binding]; other site
926570008446	active site
926570008447	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
926570008448	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570008449	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570008450	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570008451	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570008452	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; pfam01177
926570008453	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
926570008454	hypothetical protein; Provisional; Region: PRK06815
926570008455	tetramer interface [polypeptide binding]; other site
926570008456	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570008457	catalytic residue [active]
926570008458	potential frameshift: common BLAST hit: gi|295680622|ref|YP_003609196.1| Integrase catalytic region
926570008459	DDE domain; Region: DDE_Tnp_IS240; pfam13610
926570008460	DDE domain; Region: DDE_Tnp_IS240; pfam13610
926570008461	DDE domain; Region: DDE_Tnp_IS240; pfam13610
926570008462	Integrase core domain; Region: rve; pfam00665
926570008463	hypothetical protein; Provisional; Region: PRK07079
926570008464	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
926570008465	metal binding site [ion binding]; metal-binding site
926570008466	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
926570008467	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
926570008468	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570008469	catalytic residue [active]
926570008470	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
926570008471	AsnC family; Region: AsnC_trans_reg; pfam01037
926570008472	transcriptional regulator; Provisional; Region: PRK10632
926570008473	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570008474	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
926570008475	putative effector binding pocket; other site
926570008476	dimerization interface [polypeptide binding]; other site
926570008477	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926570008478	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926570008479	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570008480	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570008481	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570008482	Transposase [DNA replication, recombination, and repair]; Region: COG5433
926570008483	Protein of unknown function (DUF2384); Region: DUF2384; cl17718
926570008484	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
926570008485	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570008486	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570008487	TM-ABC transporter signature motif; other site
926570008488	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570008489	TM-ABC transporter signature motif; other site
926570008490	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570008491	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570008492	Walker A/P-loop; other site
926570008493	ATP binding site [chemical binding]; other site
926570008494	Q-loop/lid; other site
926570008495	ABC transporter signature motif; other site
926570008496	Walker B; other site
926570008497	D-loop; other site
926570008498	H-loop/switch region; other site
926570008499	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570008500	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
926570008501	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
926570008502	putative ligand binding site [chemical binding]; other site
926570008503	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
926570008504	Transcriptional regulator [Transcription]; Region: IclR; COG1414
926570008505	Bacterial transcriptional regulator; Region: IclR; pfam01614
926570008506	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
926570008507	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
926570008508	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
926570008509	Transcriptional regulators [Transcription]; Region: GntR; COG1802
926570008510	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570008511	DNA-binding site [nucleotide binding]; DNA binding site
926570008512	FCD domain; Region: FCD; pfam07729
926570008513	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926570008514	Fasciclin domain; Region: Fasciclin; pfam02469
926570008515	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
926570008516	heterotetramer interface [polypeptide binding]; other site
926570008517	active site pocket [active]
926570008518	cleavage site
926570008519	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
926570008520	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
926570008521	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
926570008522	SEC-C motif; Region: SEC-C; pfam02810
926570008523	Protein of unknown function (DUF2380); Region: DUF3280; pfam11684
926570008524	MarR family; Region: MarR; pfam01047
926570008525	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
926570008526	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
926570008527	23S rRNA interface [nucleotide binding]; other site
926570008528	L3 interface [polypeptide binding]; other site
926570008529	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570008530	active site
926570008531	PHB/PHA accumulation regulator DNA-binding domain; Region: PHB_acc_N; pfam07879
926570008532	PHB accumulation regulatory domain; Region: PHB_acc; pfam05233
926570008533	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
926570008534	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
926570008535	putative acyltransferase; Provisional; Region: PRK05790
926570008536	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926570008537	dimer interface [polypeptide binding]; other site
926570008538	active site
926570008539	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
926570008540	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
926570008541	4-aminobutyrate aminotransferase; Provisional; Region: PRK07495
926570008542	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926570008543	inhibitor-cofactor binding pocket; inhibition site
926570008544	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570008545	catalytic residue [active]
926570008546	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
926570008547	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570008548	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570008549	non-specific DNA binding site [nucleotide binding]; other site
926570008550	salt bridge; other site
926570008551	sequence-specific DNA binding site [nucleotide binding]; other site
926570008552	3-mercaptopyruvate sulfurtransferase; Region: PLN02723
926570008553	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
926570008554	active site residue [active]
926570008555	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
926570008556	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
926570008557	active site residue [active]
926570008558	cystathionine beta-lyase, bacterial; Region: cysta_beta_ly_B; TIGR01324
926570008559	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926570008560	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570008561	catalytic residue [active]
926570008562	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
926570008563	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
926570008564	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
926570008565	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
926570008566	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
926570008567	trimerization site [polypeptide binding]; other site
926570008568	active site
926570008569	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
926570008570	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
926570008571	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570008572	catalytic residue [active]
926570008573	FeS assembly protein SufD; Region: sufD; TIGR01981
926570008574	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
926570008575	FeS assembly ATPase SufC; Region: sufC; TIGR01978
926570008576	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
926570008577	Walker A/P-loop; other site
926570008578	ATP binding site [chemical binding]; other site
926570008579	Q-loop/lid; other site
926570008580	ABC transporter signature motif; other site
926570008581	Walker B; other site
926570008582	D-loop; other site
926570008583	H-loop/switch region; other site
926570008584	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
926570008585	putative ABC transporter; Region: ycf24; CHL00085
926570008586	FeS assembly SUF system regulator, gammaproteobacterial; Region: suf_reg_Xantho; TIGR02944
926570008587	Transcriptional regulator; Region: Rrf2; pfam02082
926570008588	phosphoglycolate phosphatase; Provisional; Region: PRK13222
926570008589	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570008590	motif II; other site
926570008591	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14353
926570008592	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570008593	active site
926570008594	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
926570008595	active site
926570008596	substrate binding site [chemical binding]; other site
926570008597	CoA binding site [chemical binding]; other site
926570008598	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
926570008599	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
926570008600	glutaminase active site [active]
926570008601	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
926570008602	dimer interface [polypeptide binding]; other site
926570008603	active site
926570008604	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
926570008605	dimer interface [polypeptide binding]; other site
926570008606	active site
926570008607	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
926570008608	V4R domain; Region: V4R; cl15268
926570008609	magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; Region: BchE; TIGR02026
926570008610	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
926570008611	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570008612	FeS/SAM binding site; other site
926570008613	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570008614	dimerization interface [polypeptide binding]; other site
926570008615	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
926570008616	DNA binding residues [nucleotide binding]
926570008617	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
926570008618	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
926570008619	putative substrate binding pocket [chemical binding]; other site
926570008620	AC domain interface; other site
926570008621	catalytic triad [active]
926570008622	AB domain interface; other site
926570008623	interchain disulfide; other site
926570008624	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926570008625	acetyl-CoA synthetase; Provisional; Region: PRK00174
926570008626	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
926570008627	active site
926570008628	CoA binding site [chemical binding]; other site
926570008629	acyl-activating enzyme (AAE) consensus motif; other site
926570008630	AMP binding site [chemical binding]; other site
926570008631	acetate binding site [chemical binding]; other site
926570008632	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
926570008633	Malic enzyme, N-terminal domain; Region: malic; pfam00390
926570008634	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
926570008635	putative NAD(P) binding site [chemical binding]; other site
926570008636	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
926570008637	lipoate-protein ligase B; Provisional; Region: PRK14341
926570008638	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
926570008639	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570008640	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570008641	Integrase core domain; Region: rve; pfam00665
926570008642	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
926570008643	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
926570008644	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926570008645	PYR/PP interface [polypeptide binding]; other site
926570008646	dimer interface [polypeptide binding]; other site
926570008647	TPP binding site [chemical binding]; other site
926570008648	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926570008649	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926570008650	TPP-binding site [chemical binding]; other site
926570008651	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926570008652	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926570008653	substrate binding site [chemical binding]; other site
926570008654	ATP binding site [chemical binding]; other site
926570008655	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
926570008656	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
926570008657	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570008658	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570008659	Walker A/P-loop; other site
926570008660	ATP binding site [chemical binding]; other site
926570008661	Q-loop/lid; other site
926570008662	ABC transporter signature motif; other site
926570008663	Walker B; other site
926570008664	D-loop; other site
926570008665	H-loop/switch region; other site
926570008666	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570008667	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570008668	TM-ABC transporter signature motif; other site
926570008669	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_4; cd06312
926570008670	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570008671	putative ligand binding site [chemical binding]; other site
926570008672	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
926570008673	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570008674	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570008675	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570008676	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570008677	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926570008678	DNA interaction; other site
926570008679	Metal-binding active site; metal-binding site
926570008680	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926570008681	DNA binding site [nucleotide binding]
926570008682	domain linker motif; other site
926570008683	Periplasmic sugar-binding domain of uncharacterized transport systems; Region: PBP1_uncharacterized_sugar_binding; cd06307
926570008684	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570008685	putative ligand binding site [chemical binding]; other site
926570008686	2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514
926570008687	short chain dehydrogenase; Provisional; Region: PRK06198
926570008688	classical (c) SDRs; Region: SDR_c; cd05233
926570008689	NAD(P) binding site [chemical binding]; other site
926570008690	active site
926570008691	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926570008692	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
926570008693	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
926570008694	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
926570008695	putative active site [active]
926570008696	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
926570008697	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926570008698	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
926570008699	ligand binding site [chemical binding]; other site
926570008700	NAD binding site [chemical binding]; other site
926570008701	dimerization interface [polypeptide binding]; other site
926570008702	catalytic site [active]
926570008703	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570008704	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570008705	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570008706	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926570008707	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926570008708	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926570008709	Uncharacterized protein conserved in bacteria (DUF2309); Region: DUF2309; pfam10070
926570008710	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3002
926570008711	NADH dehydrogenase subunit L; Provisional; Region: PRK08168
926570008712	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926570008713	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570008714	aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339
926570008715	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570008716	dimerization interface [polypeptide binding]; other site
926570008717	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570008718	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570008719	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570008720	RNA polymerase sigma factor; Reviewed; Region: PRK05602
926570008721	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926570008722	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
926570008723	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
926570008724	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
926570008725	DNA photolyase; Region: DNA_photolyase; pfam00875
926570008726	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
926570008727	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570008728	active site
926570008729	Int/Topo IB signature motif; other site
926570008730	DNA binding site [nucleotide binding]
926570008731	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570008732	Transposase domain (DUF772); Region: DUF772; pfam05598
926570008733	DDE superfamily endonuclease; Region: DDE_4; cl17710
926570008734	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570008735	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
926570008736	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
926570008737	dimer interface [polypeptide binding]; other site
926570008738	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926570008739	ligand binding site [chemical binding]; other site
926570008740	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
926570008741	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570008742	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570008743	Walker A/P-loop; other site
926570008744	ATP binding site [chemical binding]; other site
926570008745	Q-loop/lid; other site
926570008746	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570008747	ABC transporter signature motif; other site
926570008748	Walker B; other site
926570008749	D-loop; other site
926570008750	ABC transporter; Region: ABC_tran_2; pfam12848
926570008751	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570008752	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570008753	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
926570008754	catalytic residues [active]
926570008755	Recombinase; Region: Recombinase; pfam07508
926570008756	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
926570008757	Protein of unknown function (DUF2274); Region: DUF2274; cl02406
926570008758	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
926570008759	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
926570008760	VirB7 interaction site; other site
926570008761	conjugal transfer protein TrbF; Provisional; Region: PRK13872
926570008762	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
926570008763	conjugative transfer region protein TrbK; Region: other_trbK; TIGR04360
926570008764	conjugal transfer protein TrbJ; Provisional; Region: PRK13874
926570008765	conjugal transfer ATPase TrbE; Provisional; Region: PRK13873
926570008766	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
926570008767	Domain of unknown function DUF87; Region: DUF87; pfam01935
926570008768	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
926570008769	Type IV secretory pathway, VirB2 components (pilins) [Intracellular trafficking and secretion]; Region: VirB2; COG3838
926570008770	P-type conjugative transfer ATPase TrbB; Region: TrbB_P; TIGR02782
926570008771	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
926570008772	ATP binding site [chemical binding]; other site
926570008773	Walker A motif; other site
926570008774	hexamer interface [polypeptide binding]; other site
926570008775	Walker B motif; other site
926570008776	conjugal transfer coupling protein TraG; Provisional; Region: PRK13876
926570008777	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
926570008778	Walker A motif; other site
926570008779	ATP binding site [chemical binding]; other site
926570008780	Walker B motif; other site
926570008781	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926570008782	dimerization interface [polypeptide binding]; other site
926570008783	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
926570008784	phosphorylation site [posttranslational modification]
926570008785	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570008786	ATP binding site [chemical binding]; other site
926570008787	Mg2+ binding site [ion binding]; other site
926570008788	G-X-G motif; other site
926570008789	osmolarity response regulator; Provisional; Region: ompR; PRK09468
926570008790	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570008791	active site
926570008792	phosphorylation site [posttranslational modification]
926570008793	intermolecular recognition site; other site
926570008794	dimerization interface [polypeptide binding]; other site
926570008795	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570008796	DNA binding site [nucleotide binding]
926570008797	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570008798	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
926570008799	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926570008800	metal-binding site [ion binding]
926570008801	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926570008802	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570008803	motif II; other site
926570008804	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926570008805	metal-binding site [ion binding]
926570008806	Hg(II)-responsive transcriptional regulator; Region: MerR; TIGR02051
926570008807	Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator; Region: HTH_MerR1; cd04783
926570008808	DNA binding residues [nucleotide binding]
926570008809	dimer interface [polypeptide binding]; other site
926570008810	mercury binding site [ion binding]; other site
926570008811	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
926570008812	DDE superfamily endonuclease; Region: DDE_5; cl17874
926570008813	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
926570008814	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
926570008815	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
926570008816	dimer interface [polypeptide binding]; other site
926570008817	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570008818	catalytic residue [active]
926570008819	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
926570008820	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926570008821	metal-binding site [ion binding]
926570008822	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926570008823	Soluble P-type ATPase [General function prediction only]; Region: COG4087
926570008824	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
926570008825	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
926570008826	DNA binding residues [nucleotide binding]
926570008827	dimer interface [polypeptide binding]; other site
926570008828	copper binding site [ion binding]; other site
926570008829	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
926570008830	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570008831	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570008832	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570008833	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926570008834	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
926570008835	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
926570008836	CopC domain; Region: CopC; pfam04234
926570008837	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
926570008838	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
926570008839	Subunit I/III interface [polypeptide binding]; other site
926570008840	D-pathway; other site
926570008841	Subunit I/VIIc interface [polypeptide binding]; other site
926570008842	Subunit I/IV interface [polypeptide binding]; other site
926570008843	Subunit I/II interface [polypeptide binding]; other site
926570008844	Low-spin heme (heme a) binding site [chemical binding]; other site
926570008845	Subunit I/VIIa interface [polypeptide binding]; other site
926570008846	Subunit I/VIa interface [polypeptide binding]; other site
926570008847	Dimer interface; other site
926570008848	Putative water exit pathway; other site
926570008849	Binuclear center (heme a3/CuB) [ion binding]; other site
926570008850	K-pathway; other site
926570008851	Subunit I/Vb interface [polypeptide binding]; other site
926570008852	Putative proton exit pathway; other site
926570008853	Subunit I/VIb interface; other site
926570008854	Subunit I/VIc interface [polypeptide binding]; other site
926570008855	Electron transfer pathway; other site
926570008856	Subunit I/VIIIb interface [polypeptide binding]; other site
926570008857	Subunit I/VIIb interface [polypeptide binding]; other site
926570008858	cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00051
926570008859	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
926570008860	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
926570008861	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
926570008862	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
926570008863	dimer interface [polypeptide binding]; other site
926570008864	decamer (pentamer of dimers) interface [polypeptide binding]; other site
926570008865	catalytic triad [active]
926570008866	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926570008867	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926570008868	catalytic residues [active]
926570008869	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926570008870	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926570008871	catalytic residues [active]
926570008872	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
926570008873	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
926570008874	Cu(I) binding site [ion binding]; other site
926570008875	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570008876	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570008877	S-adenosylmethionine binding site [chemical binding]; other site
926570008878	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
926570008879	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
926570008880	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
926570008881	DsbD alpha interface [polypeptide binding]; other site
926570008882	catalytic residues [active]
926570008883	Protein of unknown function, DUF; Region: DUF411; cl01142
926570008884	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
926570008885	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
926570008886	Multicopper oxidase; Region: Cu-oxidase; pfam00394
926570008887	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
926570008888	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
926570008889	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570008890	mercuric reductase; Region: MerA; TIGR02053
926570008891	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570008892	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926570008893	Helix-Turn-Helix DNA binding domain of the CadR- and PbrR-like transcription regulators; Region: HTH_CadR-PbrR-like; cd04785
926570008894	Hg(II)-responsive transcriptional regulator; Region: MerR; TIGR02051
926570008895	DNA binding residues [nucleotide binding]
926570008896	dimer interface [polypeptide binding]; other site
926570008897	putative metal binding site [ion binding]; other site
926570008898	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
926570008899	Protein of unknown function (DUF3363); Region: DUF3363; pfam11843
926570008900	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570008901	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570008902	catalytic residue [active]
926570008903	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
926570008904	Signal peptidase, peptidase S26; Region: Peptidase_S26; pfam10502
926570008905	conjugal transfer pilin processing protease TraF; Provisional; Region: PRK13838
926570008906	Protein of unknown function (DUF2840); Region: DUF2840; pfam11000
926570008907	Replication initiator protein A; Region: RPA; cl17860
926570008908	Helix-turn-helix domain; Region: HTH_17; pfam12728
926570008909	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
926570008910	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570008911	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570008912	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
926570008913	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926570008914	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570008915	NAD(P) binding site [chemical binding]; other site
926570008916	active site
926570008917	Uncharacterized conserved protein (DUF2285); Region: DUF2285; cl02246
926570008918	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570008919	non-specific DNA binding site [nucleotide binding]; other site
926570008920	salt bridge; other site
926570008921	sequence-specific DNA binding site [nucleotide binding]; other site
926570008922	Protein of unknown function (DUF736); Region: DUF736; pfam05284
926570008923	arsenite oxidase, large subunit; Region: arsenite_ox_L; TIGR02693
926570008924	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926570008925	molybdopterin cofactor binding site; other site
926570008926	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
926570008927	molybdopterin cofactor binding site; other site
926570008928	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
926570008929	iron-sulfur cluster [ion binding]; other site
926570008930	[2Fe-2S] cluster binding site [ion binding]; other site
926570008931	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570008932	dimerization interface [polypeptide binding]; other site
926570008933	putative DNA binding site [nucleotide binding]; other site
926570008934	putative Zn2+ binding site [ion binding]; other site
926570008935	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
926570008936	Low molecular weight phosphatase family; Region: LMWPc; cd00115
926570008937	active site
926570008938	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
926570008939	ArsC family; Region: ArsC; pfam03960
926570008940	catalytic residues [active]
926570008941	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
926570008942	arsenical pump membrane protein; Provisional; Region: PRK15445
926570008943	transmembrane helices; other site
926570008944	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
926570008945	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
926570008946	Protein of unknown function (DUF2493); Region: DUF2493; pfam10686
926570008947	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
926570008948	active site
926570008949	metal binding site [ion binding]; metal-binding site
926570008950	interdomain interaction site; other site
926570008951	ParB-like nuclease domain; Region: ParB; smart00470
926570008952	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
926570008953	putative active site [active]
926570008954	homotetrameric interface [polypeptide binding]; other site
926570008955	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570008956	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
926570008957	catalytic residues [active]
926570008958	catalytic nucleophile [active]
926570008959	Recombinase; Region: Recombinase; pfam07508
926570008960	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
926570008961	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926570008962	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570008963	NAD(P) binding site [chemical binding]; other site
926570008964	active site
926570008965	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
926570008966	dimer interface [polypeptide binding]; other site
926570008967	active site
926570008968	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
926570008969	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570008970	NAD(P) binding site [chemical binding]; other site
926570008971	active site
926570008972	SOUL heme-binding protein; Region: SOUL; pfam04832
926570008973	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926570008974	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570008975	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926570008976	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926570008977	haemagglutination activity domain; Region: Haemagg_act; cl05436
926570008978	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
926570008979	metal binding site 2 [ion binding]; metal-binding site
926570008980	putative DNA binding helix; other site
926570008981	metal binding site 1 [ion binding]; metal-binding site
926570008982	structural Zn2+ binding site [ion binding]; other site
926570008983	AMP-binding domain protein; Validated; Region: PRK08315
926570008984	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570008985	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
926570008986	acyl-activating enzyme (AAE) consensus motif; other site
926570008987	putative AMP binding site [chemical binding]; other site
926570008988	putative active site [active]
926570008989	putative CoA binding site [chemical binding]; other site
926570008990	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
926570008991	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
926570008992	NADP binding site [chemical binding]; other site
926570008993	dimer interface [polypeptide binding]; other site
926570008994	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
926570008995	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
926570008996	dimer interface [polypeptide binding]; other site
926570008997	anticodon binding site; other site
926570008998	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926570008999	motif 1; other site
926570009000	dimer interface [polypeptide binding]; other site
926570009001	active site
926570009002	motif 2; other site
926570009003	GAD domain; Region: GAD; pfam02938
926570009004	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926570009005	active site
926570009006	motif 3; other site
926570009007	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
926570009008	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
926570009009	catalytic site [active]
926570009010	putative active site [active]
926570009011	putative substrate binding site [chemical binding]; other site
926570009012	HRDC domain; Region: HRDC; pfam00570
926570009013	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
926570009014	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
926570009015	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
926570009016	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
926570009017	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
926570009018	intersubunit interface [polypeptide binding]; other site
926570009019	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
926570009020	Protein of unknown function (DUF4232); Region: DUF4232; pfam14016
926570009021	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
926570009022	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
926570009023	MOFRL family; Region: MOFRL; pfam05161
926570009024	Protein of unknown function (DUF3445); Region: DUF3445; pfam11927
926570009025	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926570009026	EF-P lysine aminoacylase GenX; Region: genX; TIGR00462
926570009027	motif 1; other site
926570009028	dimer interface [polypeptide binding]; other site
926570009029	active site
926570009030	motif 2; other site
926570009031	motif 3; other site
926570009032	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
926570009033	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570009034	FeS/SAM binding site; other site
926570009035	Lysine-2,3-aminomutase; Region: LAM_C; pfam12544
926570009036	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
926570009037	Dehydroquinase class II; Region: DHquinase_II; pfam01220
926570009038	trimer interface [polypeptide binding]; other site
926570009039	active site
926570009040	dimer interface [polypeptide binding]; other site
926570009041	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
926570009042	carboxyltransferase (CT) interaction site; other site
926570009043	biotinylation site [posttranslational modification]; other site
926570009044	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
926570009045	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926570009046	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926570009047	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
926570009048	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496
926570009049	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570009050	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570009051	metal binding site [ion binding]; metal-binding site
926570009052	active site
926570009053	I-site; other site
926570009054	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570009055	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
926570009056	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
926570009057	putative molybdopterin cofactor binding site [chemical binding]; other site
926570009058	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
926570009059	putative molybdopterin cofactor binding site; other site
926570009060	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570009061	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
926570009062	amphipathic channel; other site
926570009063	Asn-Pro-Ala signature motifs; other site
926570009064	glycerol kinase; Provisional; Region: glpK; PRK00047
926570009065	Cellulomonas sp. glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_CsGK_like; cd07789
926570009066	N- and C-terminal domain interface [polypeptide binding]; other site
926570009067	active site
926570009068	MgATP binding site [chemical binding]; other site
926570009069	catalytic site [active]
926570009070	metal binding site [ion binding]; metal-binding site
926570009071	putative homotetramer interface [polypeptide binding]; other site
926570009072	glycerol binding site [chemical binding]; other site
926570009073	homodimer interface [polypeptide binding]; other site
926570009074	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
926570009075	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926570009076	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
926570009077	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926570009078	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
926570009079	heme-binding site [chemical binding]; other site
926570009080	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570009081	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570009082	dimer interface [polypeptide binding]; other site
926570009083	putative CheW interface [polypeptide binding]; other site
926570009084	putative S-transferase; Provisional; Region: PRK11752
926570009085	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
926570009086	C-terminal domain interface [polypeptide binding]; other site
926570009087	GSH binding site (G-site) [chemical binding]; other site
926570009088	dimer interface [polypeptide binding]; other site
926570009089	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
926570009090	dimer interface [polypeptide binding]; other site
926570009091	N-terminal domain interface [polypeptide binding]; other site
926570009092	active site
926570009093	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
926570009094	Uncharacterized aldehyde dehydrogenase of Synechococcus sp. PCC 7335 (EDX86601); Region: ALDH_EDX86601; cd07102
926570009095	NAD(P) binding site [chemical binding]; other site
926570009096	catalytic residues [active]
926570009097	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
926570009098	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
926570009099	tetrameric interface [polypeptide binding]; other site
926570009100	NAD binding site [chemical binding]; other site
926570009101	catalytic residues [active]
926570009102	substrate binding site [chemical binding]; other site
926570009103	amino acid permease (GABA permease); Region: 2A0304; TIGR00907
926570009104	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
926570009105	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
926570009106	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926570009107	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
926570009108	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
926570009109	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
926570009110	Iron-containing alcohol dehydrogenases-like, involved in the linear alkylbenzenesulfonate (LAS) degradation pathway; Region: Fe-ADH7; cd08192
926570009111	putative active site [active]
926570009112	metal binding site [ion binding]; metal-binding site
926570009113	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570009114	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570009115	metal binding site [ion binding]; metal-binding site
926570009116	active site
926570009117	I-site; other site
926570009118	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
926570009119	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
926570009120	putative active site [active]
926570009121	putative PHP Thumb interface [polypeptide binding]; other site
926570009122	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
926570009123	generic binding surface II; other site
926570009124	generic binding surface I; other site
926570009125	acetyl-CoA acetyltransferase; Provisional; Region: PRK07516
926570009126	Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2  has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal...; Region: SCP-x_thiolase; cd00829
926570009127	active site
926570009128	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
926570009129	classical (c) SDRs; Region: SDR_c; cd05233
926570009130	NAD(P) binding site [chemical binding]; other site
926570009131	active site
926570009132	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926570009133	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
926570009134	putative NAD(P) binding site [chemical binding]; other site
926570009135	active site
926570009136	putative substrate binding site [chemical binding]; other site
926570009137	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
926570009138	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570009139	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570009140	amidase; Provisional; Region: PRK07486
926570009141	Amidase; Region: Amidase; cl11426
926570009142	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
926570009143	ParB-like nuclease domain; Region: ParB; smart00470
926570009144	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926570009145	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570009146	P-loop; other site
926570009147	Magnesium ion binding site [ion binding]; other site
926570009148	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570009149	Magnesium ion binding site [ion binding]; other site
926570009150	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
926570009151	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
926570009152	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
926570009153	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570009154	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
926570009155	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
926570009156	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
926570009157	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
926570009158	trmE is a tRNA modification GTPase; Region: trmE; cd04164
926570009159	G1 box; other site
926570009160	Switch I region; other site
926570009161	G2 box; other site
926570009162	Switch II region; other site
926570009163	G3 box; other site
926570009164	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
926570009165	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
926570009166	dimer interface [polypeptide binding]; other site
926570009167	[2Fe-2S] cluster binding site [ion binding]; other site
926570009168	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
926570009169	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
926570009170	catalytic residues [active]
926570009171	Domain of unknown function DUF59; Region: DUF59; pfam01883
926570009172	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
926570009173	DNA polymerase III subunit chi; Validated; Region: PRK05728
926570009174	TPR repeat; Region: TPR_11; pfam13414
926570009175	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570009176	binding surface
926570009177	TPR motif; other site
926570009178	Tetratricopeptide repeat; Region: TPR_16; pfam13432
926570009179	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570009180	flavoprotein, HI0933 family; Region: TIGR00275
926570009181	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570009182	aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339
926570009183	The C-terminal substrate binding of LysR-type transcriptional regulator (CbbR) of RubisCO operon, which is involved in the carbon dioxide fixation, contains the type 2 periplasmic binding fold; Region: PBP2_CbbR_RubisCO_like; cd08419
926570009184	putative dimerization interface [polypeptide binding]; other site
926570009185	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
926570009186	Mg++ binding site [ion binding]; other site
926570009187	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
926570009188	putative catalytic motif [active]
926570009189	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
926570009190	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926570009191	Putative Catalytic site; other site
926570009192	DXD motif; other site
926570009193	Predicted membrane protein (DUF2142); Region: DUF2142; pfam09913
926570009194	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
926570009195	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
926570009196	3-hydroxyisobutyrate dehydrogenase; Region: HIBADH; TIGR01692
926570009197	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926570009198	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926570009199	DNA binding site [nucleotide binding]
926570009200	domain linker motif; other site
926570009201	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
926570009202	putative dimerization interface [polypeptide binding]; other site
926570009203	putative ligand binding site [chemical binding]; other site
926570009204	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
926570009205	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926570009206	putative aldolase; Validated; Region: PRK08130
926570009207	intersubunit interface [polypeptide binding]; other site
926570009208	active site
926570009209	Zn2+ binding site [ion binding]; other site
926570009210	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
926570009211	Protein of unknown function (DUF2889); Region: DUF2889; pfam11136
926570009212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570009213	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570009214	putative substrate translocation pore; other site
926570009215	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570009216	indolepyruvate ferredoxin oxidoreductase; Validated; Region: PRK09193
926570009217	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
926570009218	dimer interface [polypeptide binding]; other site
926570009219	PYR/PP interface [polypeptide binding]; other site
926570009220	TPP binding site [chemical binding]; other site
926570009221	substrate binding site [chemical binding]; other site
926570009222	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926570009223	TPP-binding site [chemical binding]; other site
926570009224	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546
926570009225	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
926570009226	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
926570009227	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570009228	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570009229	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
926570009230	putative effector binding pocket; other site
926570009231	dimerization interface [polypeptide binding]; other site
926570009232	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
926570009233	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570009234	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570009235	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926570009236	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570009237	putative DNA binding site [nucleotide binding]; other site
926570009238	putative Zn2+ binding site [ion binding]; other site
926570009239	AsnC family; Region: AsnC_trans_reg; pfam01037
926570009240	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
926570009241	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
926570009242	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
926570009243	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
926570009244	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
926570009245	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
926570009246	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
926570009247	Surface antigen; Region: Bac_surface_Ag; pfam01103
926570009248	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
926570009249	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
926570009250	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
926570009251	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
926570009252	trimer interface [polypeptide binding]; other site
926570009253	active site
926570009254	UDP-GlcNAc binding site [chemical binding]; other site
926570009255	lipid binding site [chemical binding]; lipid-binding site
926570009256	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
926570009257	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
926570009258	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
926570009259	active site
926570009260	Protein of unknown function (DUF1009); Region: DUF1009; pfam06230
926570009261	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
926570009262	dimer interface [polypeptide binding]; other site
926570009263	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926570009264	active site
926570009265	metal binding site [ion binding]; metal-binding site
926570009266	glutathione binding site [chemical binding]; other site
926570009267	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
926570009268	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
926570009269	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926570009270	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
926570009271	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570009272	Walker A/P-loop; other site
926570009273	ATP binding site [chemical binding]; other site
926570009274	Q-loop/lid; other site
926570009275	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570009276	ABC transporter; Region: ABC_tran_2; pfam12848
926570009277	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926570009278	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
926570009279	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
926570009280	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
926570009281	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07656
926570009282	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926570009283	Subfamily of fatty acid CoA ligase (FACL) similar to Fum10p of Gibberella moniliformis; Region: FACL_fum10p_like; cd05926
926570009284	acyl-activating enzyme (AAE) consensus motif; other site
926570009285	putative AMP binding site [chemical binding]; other site
926570009286	putative active site [active]
926570009287	putative CoA binding site [chemical binding]; other site
926570009288	pyridine nucleotide-disulfide oxidoreductase family protein; Region: Nterm_to_SelD; TIGR03169
926570009289	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926570009290	metal-binding site [ion binding]
926570009291	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926570009292	metal-binding site [ion binding]
926570009293	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
926570009294	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926570009295	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
926570009296	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
926570009297	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570009298	NAD(P) binding site [chemical binding]; other site
926570009299	active site
926570009300	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
926570009301	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
926570009302	inhibitor site; inhibition site
926570009303	active site
926570009304	dimer interface [polypeptide binding]; other site
926570009305	catalytic residue [active]
926570009306	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
926570009307	Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156
926570009308	putative ligand binding site [chemical binding]; other site
926570009309	NAD binding site [chemical binding]; other site
926570009310	catalytic site [active]
926570009311	dihydroxy-acid dehydratase; Validated; Region: PRK06131
926570009312	hypothetical protein; Validated; Region: PRK08245
926570009313	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
926570009314	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
926570009315	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570009316	motif II; other site
926570009317	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
926570009318	Ferrochelatase; Region: Ferrochelatase; pfam00762
926570009319	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
926570009320	C-terminal domain interface [polypeptide binding]; other site
926570009321	active site
926570009322	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
926570009323	active site
926570009324	N-terminal domain interface [polypeptide binding]; other site
926570009325	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
926570009326	substrate binding site [chemical binding]; other site
926570009327	active site
926570009328	PEP synthetase regulatory protein; Provisional; Region: PRK05339
926570009329	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
926570009330	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
926570009331	DNA binding site [nucleotide binding]
926570009332	active site
926570009333	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
926570009334	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
926570009335	NADP binding site [chemical binding]; other site
926570009336	dimer interface [polypeptide binding]; other site
926570009337	CHRD domain; Region: CHRD; pfam07452
926570009338	Dihydroneopterin aldolase; Region: FolB; smart00905
926570009339	active site
926570009340	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
926570009341	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
926570009342	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
926570009343	tetramer interface [polypeptide binding]; other site
926570009344	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
926570009345	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
926570009346	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
926570009347	Sel1-like repeats; Region: SEL1; smart00671
926570009348	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
926570009349	dimer interface [polypeptide binding]; other site
926570009350	substrate binding site [chemical binding]; other site
926570009351	metal binding sites [ion binding]; metal-binding site
926570009352	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570009353	NAD(P) binding site [chemical binding]; other site
926570009354	active site
926570009355	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926570009356	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
926570009357	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
926570009358	Cell division protein ZapA; Region: ZapA; pfam05164
926570009359	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
926570009360	aspartate aminotransferase; Provisional; Region: PRK06108
926570009361	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570009362	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570009363	homodimer interface [polypeptide binding]; other site
926570009364	catalytic residue [active]
926570009365	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
926570009366	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
926570009367	P loop; other site
926570009368	GTP binding site [chemical binding]; other site
926570009369	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
926570009370	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
926570009371	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570009372	FeS/SAM binding site; other site
926570009373	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
926570009374	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
926570009375	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
926570009376	amino acid transporter; Region: 2A0306; TIGR00909
926570009377	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
926570009378	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
926570009379	minor groove reading motif; other site
926570009380	helix-hairpin-helix signature motif; other site
926570009381	substrate binding pocket [chemical binding]; other site
926570009382	active site
926570009383	Integral membrane protein (DUF2244); Region: DUF2244; pfam10003
926570009384	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
926570009385	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570009386	putative substrate translocation pore; other site
926570009387	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
926570009388	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
926570009389	ring oligomerisation interface [polypeptide binding]; other site
926570009390	ATP/Mg binding site [chemical binding]; other site
926570009391	stacking interactions; other site
926570009392	hinge regions; other site
926570009393	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
926570009394	oligomerisation interface [polypeptide binding]; other site
926570009395	mobile loop; other site
926570009396	roof hairpin; other site
926570009397	Usg-like family; Region: Usg; pfam06233
926570009398	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
926570009399	Terminase-like family; Region: Terminase_6; pfam03237
926570009400	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
926570009401	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
926570009402	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
926570009403	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
926570009404	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
926570009405	Baseplate J-like protein; Region: Baseplate_J; cl01294
926570009406	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
926570009407	Right handed beta helix region; Region: Beta_helix; pfam13229
926570009408	Periplasmic copper-binding protein (NosD); Region: NosD; pfam05048
926570009409	Right handed beta helix region; Region: Beta_helix; pfam13229
926570009410	Transposase domain (DUF772); Region: DUF772; pfam05598
926570009411	polyphosphate kinase; Provisional; Region: PRK05443
926570009412	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
926570009413	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
926570009414	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
926570009415	putative domain interface [polypeptide binding]; other site
926570009416	putative active site [active]
926570009417	catalytic site [active]
926570009418	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
926570009419	putative active site [active]
926570009420	catalytic site [active]
926570009421	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
926570009422	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
926570009423	Domain of unknown function DUF20; Region: UPF0118; pfam01594
926570009424	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
926570009425	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
926570009426	dimerization interface [polypeptide binding]; other site
926570009427	putative ATP binding site [chemical binding]; other site
926570009428	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
926570009429	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
926570009430	active site
926570009431	substrate binding site [chemical binding]; other site
926570009432	cosubstrate binding site; other site
926570009433	catalytic site [active]
926570009434	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
926570009435	EamA-like transporter family; Region: EamA; pfam00892
926570009436	EamA-like transporter family; Region: EamA; pfam00892
926570009437	ornithine carbamoyltransferase; Provisional; Region: PRK00779
926570009438	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
926570009439	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
926570009440	acetylornithine transaminase protein; Provisional; Region: argD; PRK01278
926570009441	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926570009442	inhibitor-cofactor binding pocket; inhibition site
926570009443	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570009444	catalytic residue [active]
926570009445	exopolyphosphatase; Region: exo_poly_only; TIGR03706
926570009446	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
926570009447	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
926570009448	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; pfam09982
926570009449	Uncharacterized conserved protein [Function unknown]; Region: COG2127
926570009450	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
926570009451	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570009452	Walker A motif; other site
926570009453	ATP binding site [chemical binding]; other site
926570009454	Walker B motif; other site
926570009455	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; cl02059
926570009456	arginine finger; other site
926570009457	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570009458	Walker A motif; other site
926570009459	ATP binding site [chemical binding]; other site
926570009460	Walker B motif; other site
926570009461	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
926570009462	oligosaccharyl transferase, archaeosortase A system-associated; Region: archaeo_STT3; TIGR04154
926570009463	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
926570009464	Cysteine-rich domain; Region: CCG; pfam02754
926570009465	FAD binding domain; Region: FAD_binding_4; pfam01565
926570009466	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
926570009467	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
926570009468	FAD binding domain; Region: FAD_binding_4; pfam01565
926570009469	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
926570009470	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
926570009471	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
926570009472	homodimer interface [polypeptide binding]; other site
926570009473	substrate-cofactor binding pocket; other site
926570009474	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570009475	catalytic residue [active]
926570009476	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
926570009477	putative nucleotide binding site [chemical binding]; other site
926570009478	uridine monophosphate binding site [chemical binding]; other site
926570009479	homohexameric interface [polypeptide binding]; other site
926570009480	ribosome recycling factor; Reviewed; Region: frr; PRK00083
926570009481	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
926570009482	hinge region; other site
926570009483	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
926570009484	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
926570009485	catalytic residue [active]
926570009486	putative FPP diphosphate  binding site; other site
926570009487	putative FPP binding hydrophobic cleft; other site
926570009488	dimer interface [polypeptide binding]; other site
926570009489	putative IPP diphosphate binding site; other site
926570009490	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
926570009491	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
926570009492	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
926570009493	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
926570009494	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
926570009495	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
926570009496	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
926570009497	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
926570009498	active site
926570009499	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
926570009500	protein binding site [polypeptide binding]; other site
926570009501	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
926570009502	putative substrate binding region [chemical binding]; other site
926570009503	ketol-acid reductoisomerase; Provisional; Region: PRK05479
926570009504	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
926570009505	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
926570009506	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
926570009507	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
926570009508	dimer interface [polypeptide binding]; other site
926570009509	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570009510	catalytic residue [active]
926570009511	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
926570009512	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
926570009513	HAD-superfamily class IIA hydrolase, TIGR01459; Region: HAD-SF-IIA-hyp4
926570009514	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570009515	active site
926570009516	motif I; other site
926570009517	motif II; other site
926570009518	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570009519	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926570009520	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926570009521	nucleotide binding site [chemical binding]; other site
926570009522	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
926570009523	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926570009524	DNA binding residues [nucleotide binding]
926570009525	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
926570009526	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926570009527	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926570009528	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570009529	putative PBP binding loops; other site
926570009530	dimer interface [polypeptide binding]; other site
926570009531	ABC-ATPase subunit interface; other site
926570009532	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926570009533	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926570009534	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926570009535	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570009536	Walker A/P-loop; other site
926570009537	ATP binding site [chemical binding]; other site
926570009538	Q-loop/lid; other site
926570009539	ABC transporter signature motif; other site
926570009540	Walker B; other site
926570009541	D-loop; other site
926570009542	H-loop/switch region; other site
926570009543	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926570009544	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
926570009545	Walker A/P-loop; other site
926570009546	ATP binding site [chemical binding]; other site
926570009547	Q-loop/lid; other site
926570009548	ABC transporter signature motif; other site
926570009549	Walker B; other site
926570009550	D-loop; other site
926570009551	H-loop/switch region; other site
926570009552	TOBE domain; Region: TOBE_2; pfam08402
926570009553	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926570009554	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
926570009555	putative N- and C-terminal domain interface [polypeptide binding]; other site
926570009556	putative active site [active]
926570009557	MgATP binding site [chemical binding]; other site
926570009558	catalytic site [active]
926570009559	metal binding site [ion binding]; metal-binding site
926570009560	putative xylulose binding site [chemical binding]; other site
926570009561	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
926570009562	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926570009563	putative ligand binding site [chemical binding]; other site
926570009564	putative NAD binding site [chemical binding]; other site
926570009565	catalytic site [active]
926570009566	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
926570009567	intersubunit interface [polypeptide binding]; other site
926570009568	active site
926570009569	Zn2+ binding site [ion binding]; other site
926570009570	glycerol-3-phosphate dehydrogenase; Provisional; Region: PRK13369
926570009571	Uncharacterized conserved protein [Function unknown]; Region: COG3347
926570009572	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
926570009573	Predicted membrane protein [Function unknown]; Region: COG2860
926570009574	UPF0126 domain; Region: UPF0126; pfam03458
926570009575	UPF0126 domain; Region: UPF0126; pfam03458
926570009576	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926570009577	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926570009578	active site
926570009579	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
926570009580	CoA-transferase family III; Region: CoA_transf_3; pfam02515
926570009581	Uncharacterized conserved protein [Function unknown]; Region: COG3777
926570009582	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926570009583	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926570009584	active site 2 [active]
926570009585	active site 1 [active]
926570009586	enoyl-CoA hydratase; Region: PLN02864
926570009587	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926570009588	HDE_HSD  The R-hydratase-like hot dog fold of the 17-beta-hydroxysteriod dehydrogenase (HSD), and Hydratase-Dehydrogenase-Epimerase (HDE) proteins.  Other enzymes with this fold include MaoC dehydratase, and the fatty acid synthase beta subunit; Region: HDE_HSD; cd03448
926570009589	dimer interaction site [polypeptide binding]; other site
926570009590	substrate-binding tunnel; other site
926570009591	active site
926570009592	catalytic site [active]
926570009593	substrate binding site [chemical binding]; other site
926570009594	short chain dehydrogenase; Provisional; Region: PRK07791
926570009595	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570009596	NAD(P) binding site [chemical binding]; other site
926570009597	active site
926570009598	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39G; cd02423
926570009599	putative active site [active]
926570009600	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
926570009601	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
926570009602	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570009603	Walker A motif; other site
926570009604	ATP binding site [chemical binding]; other site
926570009605	Walker B motif; other site
926570009606	arginine finger; other site
926570009607	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570009608	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
926570009609	HAMP domain; Region: HAMP; pfam00672
926570009610	dimerization interface [polypeptide binding]; other site
926570009611	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570009612	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570009613	dimer interface [polypeptide binding]; other site
926570009614	putative CheW interface [polypeptide binding]; other site
926570009615	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
926570009616	Strictosidine synthase; Region: Str_synth; pfam03088
926570009617	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570009618	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570009619	TM-ABC transporter signature motif; other site
926570009620	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570009621	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570009622	TM-ABC transporter signature motif; other site
926570009623	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570009624	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570009625	Walker A/P-loop; other site
926570009626	ATP binding site [chemical binding]; other site
926570009627	Q-loop/lid; other site
926570009628	ABC transporter signature motif; other site
926570009629	Walker B; other site
926570009630	D-loop; other site
926570009631	H-loop/switch region; other site
926570009632	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570009633	Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type I periplasmic binding protein superfamily; Region: PBP1_ABC_sugar_binding_like_1; cd06300
926570009634	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570009635	putative ligand binding site [chemical binding]; other site
926570009636	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
926570009637	Strictosidine synthase; Region: Str_synth; pfam03088
926570009638	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
926570009639	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
926570009640	active site
926570009641	intersubunit interface [polypeptide binding]; other site
926570009642	catalytic residue [active]
926570009643	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
926570009644	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK12825
926570009645	classical (c) SDRs; Region: SDR_c; cd05233
926570009646	NAD(P) binding site [chemical binding]; other site
926570009647	active site
926570009648	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570009649	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570009650	Walker A/P-loop; other site
926570009651	ATP binding site [chemical binding]; other site
926570009652	Q-loop/lid; other site
926570009653	ABC transporter signature motif; other site
926570009654	Walker B; other site
926570009655	D-loop; other site
926570009656	H-loop/switch region; other site
926570009657	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570009658	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570009659	TM-ABC transporter signature motif; other site
926570009660	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_4; cd06312
926570009661	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570009662	putative ligand binding site [chemical binding]; other site
926570009663	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570009664	glucose-1-dehydrogenase; Provisional; Region: PRK08936
926570009665	NAD(P) binding site [chemical binding]; other site
926570009666	active site
926570009667	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926570009668	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570009669	ligand binding site [chemical binding]; other site
926570009670	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570009671	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570009672	TM-ABC transporter signature motif; other site
926570009673	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570009674	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570009675	Walker A/P-loop; other site
926570009676	ATP binding site [chemical binding]; other site
926570009677	Q-loop/lid; other site
926570009678	ABC transporter signature motif; other site
926570009679	Walker B; other site
926570009680	D-loop; other site
926570009681	H-loop/switch region; other site
926570009682	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
926570009683	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
926570009684	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
926570009685	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
926570009686	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
926570009687	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
926570009688	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
926570009689	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
926570009690	FAD binding pocket [chemical binding]; other site
926570009691	FAD binding motif [chemical binding]; other site
926570009692	phosphate binding motif [ion binding]; other site
926570009693	beta-alpha-beta structure motif; other site
926570009694	NAD(p) ribose binding residues [chemical binding]; other site
926570009695	NAD binding pocket [chemical binding]; other site
926570009696	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
926570009697	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570009698	catalytic loop [active]
926570009699	iron binding site [ion binding]; other site
926570009700	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
926570009701	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
926570009702	gating phenylalanine in ion channel; other site
926570009703	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
926570009704	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
926570009705	DAK2 domain; Region: Dak2; cl03685
926570009706	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
926570009707	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
926570009708	dimerization domain swap beta strand [polypeptide binding]; other site
926570009709	regulatory protein interface [polypeptide binding]; other site
926570009710	active site
926570009711	regulatory phosphorylation site [posttranslational modification]; other site
926570009712	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
926570009713	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926570009714	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926570009715	Hint domain; Region: Hint_2; pfam13403
926570009716	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
926570009717	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
926570009718	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
926570009719	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
926570009720	hypothetical protein; Reviewed; Region: PRK00024
926570009721	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
926570009722	MPN+ (JAMM) motif; other site
926570009723	Zinc-binding site [ion binding]; other site
926570009724	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
926570009725	homotrimer interaction site [polypeptide binding]; other site
926570009726	putative active site [active]
926570009727	CHAP domain; Region: CHAP; cl17642
926570009728	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
926570009729	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
926570009730	S-adenosylmethionine binding site [chemical binding]; other site
926570009731	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
926570009732	SurA N-terminal domain; Region: SurA_N; pfam09312
926570009733	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
926570009734	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
926570009735	OstA-like protein; Region: OstA; cl00844
926570009736	Organic solvent tolerance protein; Region: OstA_C; pfam04453
926570009737	Predicted permeases [General function prediction only]; Region: COG0795
926570009738	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
926570009739	Predicted permeases [General function prediction only]; Region: COG0795
926570009740	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
926570009741	pyridoxine 5'-phosphate synthase; Provisional; Region: PRK05265
926570009742	active site
926570009743	hydrophilic channel; other site
926570009744	dimerization interface [polypeptide binding]; other site
926570009745	catalytic residues [active]
926570009746	active site lid [active]
926570009747	Pyridoxal phosphate biosynthetic protein PdxA; Region: PdxA; cl00873
926570009748	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
926570009749	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
926570009750	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
926570009751	putative dimer interface [polypeptide binding]; other site
926570009752	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00528
926570009753	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926570009754	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570009755	S-adenosylmethionine binding site [chemical binding]; other site
926570009756	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
926570009757	endonuclease III; Region: ENDO3c; smart00478
926570009758	minor groove reading motif; other site
926570009759	helix-hairpin-helix signature motif; other site
926570009760	substrate binding pocket [chemical binding]; other site
926570009761	active site
926570009762	Permease family; Region: Xan_ur_permease; cl00967
926570009763	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
926570009764	DEAD-like helicases superfamily; Region: DEXDc; smart00487
926570009765	ATP binding site [chemical binding]; other site
926570009766	Mg++ binding site [ion binding]; other site
926570009767	motif III; other site
926570009768	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570009769	nucleotide binding region [chemical binding]; other site
926570009770	ATP-binding site [chemical binding]; other site
926570009771	GAF domain; Region: GAF; pfam01590
926570009772	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570009773	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
926570009774	Walker A motif; other site
926570009775	ATP binding site [chemical binding]; other site
926570009776	Walker B motif; other site
926570009777	arginine finger; other site
926570009778	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570009779	DNA-binding interface [nucleotide binding]; DNA binding site
926570009780	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
926570009781	D-arabinose dehydrogenase; Region: arabinose_DH_like; cd05284
926570009782	NAD binding site [chemical binding]; other site
926570009783	substrate binding site [chemical binding]; other site
926570009784	catalytic Zn binding site [ion binding]; other site
926570009785	structural Zn binding site [ion binding]; other site
926570009786	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
926570009787	active site
926570009788	Domain of unknown function DUF59; Region: DUF59; pfam01883
926570009789	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
926570009790	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
926570009791	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
926570009792	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926570009793	molybdopterin cofactor binding site; other site
926570009794	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926570009795	The MopB_CT_2 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is...; Region: MopB_CT_2; cd02783
926570009796	putative molybdopterin cofactor binding site; other site
926570009797	tyrosine decarboxylase; Region: PLN02880
926570009798	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926570009799	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570009800	catalytic residue [active]
926570009801	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
926570009802	Protein export membrane protein; Region: SecD_SecF; cl14618
926570009803	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
926570009804	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926570009805	HlyD family secretion protein; Region: HlyD_3; pfam13437
926570009806	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
926570009807	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
926570009808	ligand binding site [chemical binding]; other site
926570009809	NAD binding site [chemical binding]; other site
926570009810	dimerization interface [polypeptide binding]; other site
926570009811	catalytic site [active]
926570009812	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
926570009813	putative L-serine binding site [chemical binding]; other site
926570009814	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cd01494
926570009815	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570009816	catalytic residue [active]
926570009817	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
926570009818	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926570009819	RNA binding surface [nucleotide binding]; other site
926570009820	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
926570009821	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570009822	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570009823	non-specific DNA binding site [nucleotide binding]; other site
926570009824	salt bridge; other site
926570009825	sequence-specific DNA binding site [nucleotide binding]; other site
926570009826	NusB family; Region: NusB; pfam01029
926570009827	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
926570009828	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
926570009829	YGGT family; Region: YGGT; pfam02325
926570009830	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14188
926570009831	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
926570009832	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
926570009833	homodimer interface [polypeptide binding]; other site
926570009834	NADP binding site [chemical binding]; other site
926570009835	substrate binding site [chemical binding]; other site
926570009836	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
926570009837	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570009838	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570009839	catalytic residue [active]
926570009840	Sporulation related domain; Region: SPOR; pfam05036
926570009841	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926570009842	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926570009843	active site
926570009844	catalytic tetrad [active]
926570009845	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
926570009846	GTP cyclohydrolase I; Provisional; Region: PLN03044
926570009847	active site
926570009848	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
926570009849	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570009850	TPR repeat; Region: TPR_11; pfam13414
926570009851	binding surface
926570009852	TPR motif; other site
926570009853	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570009854	binding surface
926570009855	TPR motif; other site
926570009856	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14608
926570009857	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
926570009858	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
926570009859	putative active site [active]
926570009860	catalytic triad [active]
926570009861	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
926570009862	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
926570009863	dimerization interface [polypeptide binding]; other site
926570009864	ATP binding site [chemical binding]; other site
926570009865	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
926570009866	dimerization interface [polypeptide binding]; other site
926570009867	ATP binding site [chemical binding]; other site
926570009868	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
926570009869	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
926570009870	putative GSH binding site [chemical binding]; other site
926570009871	catalytic residues [active]
926570009872	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
926570009873	pyruvate carboxylase; Reviewed; Region: PRK12999
926570009874	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926570009875	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926570009876	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
926570009877	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
926570009878	active site
926570009879	catalytic residues [active]
926570009880	metal binding site [ion binding]; metal-binding site
926570009881	homodimer binding site [polypeptide binding]; other site
926570009882	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
926570009883	carboxyltransferase (CT) interaction site; other site
926570009884	biotinylation site [posttranslational modification]; other site
926570009885	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
926570009886	MarC family integral membrane protein; Region: MarC; cl00919
926570009887	Putative mono-oxygenase ydhR; Region: ydhR; cl07420
926570009888	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570009889	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570009890	glutamyl-tRNA synthetase; Provisional; Region: PRK12558
926570009891	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
926570009892	active site
926570009893	HIGH motif; other site
926570009894	nucleotide binding site [chemical binding]; other site
926570009895	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
926570009896	active site
926570009897	KMSKS motif; other site
926570009898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570009899	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570009900	putative substrate translocation pore; other site
926570009901	manganese transport regulator MntR; Provisional; Region: PRK11050
926570009902	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
926570009903	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
926570009904	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
926570009905	Acylphosphatases [Energy production and conversion]; Region: AcyP; COG1254
926570009906	ATP12 chaperone protein; Region: ATP12; pfam07542
926570009907	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
926570009908	Predicted nucleoside-diphosphate-sugar epimerase [Cell envelope biogenesis, outer membrane]; Region: COG3660
926570009909	Mitochondrial fission ELM1; Region: Mito_fiss_Elm1; pfam06258
926570009910	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_7; cd06910
926570009911	putative active site [active]
926570009912	Zn binding site [ion binding]; other site
926570009913	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
926570009914	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
926570009915	CDP-alcohol phosphatidyltransferase 2; Region: CDP-OH_P_tran_2; pfam08009
926570009916	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
926570009917	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
926570009918	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926570009919	Possible lysine decarboxylase; Region: Lysine_decarbox; pfam03641
926570009920	Domain of unknown function (DUF329); Region: DUF329; pfam03884
926570009921	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
926570009922	RNA binding site [nucleotide binding]; other site
926570009923	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
926570009924	Maf-like protein; Region: Maf; pfam02545
926570009925	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
926570009926	active site
926570009927	dimer interface [polypeptide binding]; other site
926570009928	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
926570009929	rRNA binding site [nucleotide binding]; other site
926570009930	predicted 30S ribosome binding site; other site
926570009931	histidinol dehydrogenase; Region: hisD; TIGR00069
926570009932	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
926570009933	NAD binding site [chemical binding]; other site
926570009934	dimerization interface [polypeptide binding]; other site
926570009935	product binding site; other site
926570009936	substrate binding site [chemical binding]; other site
926570009937	zinc binding site [ion binding]; other site
926570009938	catalytic residues [active]
926570009939	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
926570009940	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
926570009941	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
926570009942	active site
926570009943	catalytic residues [active]
926570009944	metal binding site [ion binding]; metal-binding site
926570009945	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
926570009946	CoA-transferase family III; Region: CoA_transf_3; pfam02515
926570009947	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
926570009948	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926570009949	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926570009950	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
926570009951	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926570009952	FeS/SAM binding site; other site
926570009953	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570009954	NAD(P) binding site [chemical binding]; other site
926570009955	active site
926570009956	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
926570009957	Putative bacterial sensory transduction regulator; Region: YbjN; cl15834
926570009958	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
926570009959	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
926570009960	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570009961	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570009962	dimer interface [polypeptide binding]; other site
926570009963	putative CheW interface [polypeptide binding]; other site
926570009964	STAS domain; Region: STAS_2; pfam13466
926570009965	Response regulator receiver domain; Region: Response_reg; pfam00072
926570009966	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570009967	active site
926570009968	phosphorylation site [posttranslational modification]
926570009969	intermolecular recognition site; other site
926570009970	dimerization interface [polypeptide binding]; other site
926570009971	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
926570009972	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
926570009973	putative binding surface; other site
926570009974	active site
926570009975	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
926570009976	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570009977	ATP binding site [chemical binding]; other site
926570009978	Mg2+ binding site [ion binding]; other site
926570009979	G-X-G motif; other site
926570009980	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
926570009981	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
926570009982	putative CheA interaction surface; other site
926570009983	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
926570009984	Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138
926570009985	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
926570009986	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
926570009987	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570009988	active site
926570009989	phosphorylation site [posttranslational modification]
926570009990	intermolecular recognition site; other site
926570009991	dimerization interface [polypeptide binding]; other site
926570009992	CheB methylesterase; Region: CheB_methylest; pfam01339
926570009993	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
926570009994	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570009995	active site
926570009996	phosphorylation site [posttranslational modification]
926570009997	intermolecular recognition site; other site
926570009998	dimerization interface [polypeptide binding]; other site
926570009999	CheD chemotactic sensory transduction; Region: CheD; cl00810
926570010000	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
926570010001	SnoaL-like domain; Region: SnoaL_2; pfam12680
926570010002	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926570010003	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
926570010004	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
926570010005	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926570010006	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926570010007	DNA binding residues [nucleotide binding]
926570010008	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
926570010009	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926570010010	RNA binding surface [nucleotide binding]; other site
926570010011	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
926570010012	active site
926570010013	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; pfam10013
926570010014	tricarballylate dehydrogenase; Validated; Region: PRK08274
926570010015	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926570010016	tricarballylate utilization protein B; Provisional; Region: PRK15033
926570010017	metabolite-proton symporter; Region: 2A0106; TIGR00883
926570010018	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570010019	putative substrate translocation pore; other site
926570010020	allophanate hydrolase; Provisional; Region: PRK08186
926570010021	Amidase; Region: Amidase; cl11426
926570010022	urea carboxylase; Region: urea_carbox; TIGR02712
926570010023	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926570010024	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926570010025	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
926570010026	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
926570010027	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
926570010028	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
926570010029	carboxyltransferase (CT) interaction site; other site
926570010030	biotinylation site [posttranslational modification]; other site
926570010031	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
926570010032	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
926570010033	Domain of unknown function (DUF1989); Region: DUF1989; cl01474
926570010034	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926570010035	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926570010036	Walker A/P-loop; other site
926570010037	ATP binding site [chemical binding]; other site
926570010038	Q-loop/lid; other site
926570010039	ABC transporter signature motif; other site
926570010040	Walker B; other site
926570010041	D-loop; other site
926570010042	H-loop/switch region; other site
926570010043	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926570010044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570010045	dimer interface [polypeptide binding]; other site
926570010046	conserved gate region; other site
926570010047	putative PBP binding loops; other site
926570010048	ABC-ATPase subunit interface; other site
926570010049	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
926570010050	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
926570010051	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
926570010052	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
926570010053	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
926570010054	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
926570010055	inhibitor site; inhibition site
926570010056	active site
926570010057	dimer interface [polypeptide binding]; other site
926570010058	catalytic residue [active]
926570010059	Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988
926570010060	Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988
926570010061	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
926570010062	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
926570010063	catalytic residue [active]
926570010064	putative FPP diphosphate  binding site; other site
926570010065	putative FPP binding hydrophobic cleft; other site
926570010066	dimer interface [polypeptide binding]; other site
926570010067	putative IPP diphosphate binding site; other site
926570010068	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570010069	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
926570010070	dimerization interface [polypeptide binding]; other site
926570010071	substrate binding pocket [chemical binding]; other site
926570010072	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926570010073	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926570010074	substrate binding pocket [chemical binding]; other site
926570010075	membrane-bound complex binding site; other site
926570010076	hinge residues; other site
926570010077	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570010078	dimer interface [polypeptide binding]; other site
926570010079	conserved gate region; other site
926570010080	putative PBP binding loops; other site
926570010081	ABC-ATPase subunit interface; other site
926570010082	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
926570010083	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570010084	Walker A/P-loop; other site
926570010085	ATP binding site [chemical binding]; other site
926570010086	Q-loop/lid; other site
926570010087	ABC transporter signature motif; other site
926570010088	Walker B; other site
926570010089	D-loop; other site
926570010090	H-loop/switch region; other site
926570010091	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
926570010092	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
926570010093	tetramer interface [polypeptide binding]; other site
926570010094	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926570010095	active site
926570010096	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
926570010097	dimer interface [polypeptide binding]; other site
926570010098	putative tRNA-binding site [nucleotide binding]; other site
926570010099	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
926570010100	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
926570010101	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
926570010102	elongation factor G; Reviewed; Region: PRK12740
926570010103	G1 box; other site
926570010104	GTP/Mg2+ binding site [chemical binding]; other site
926570010105	G3 box; other site
926570010106	Switch II region; other site
926570010107	G4 box; other site
926570010108	G5 box; other site
926570010109	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
926570010110	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
926570010111	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
926570010112	enoyl-CoA hydratase; Validated; Region: PRK08139
926570010113	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926570010114	substrate binding site [chemical binding]; other site
926570010115	oxyanion hole (OAH) forming residues; other site
926570010116	trimer interface [polypeptide binding]; other site
926570010117	acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829
926570010118	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
926570010119	NAD(P) binding site [chemical binding]; other site
926570010120	homotetramer interface [polypeptide binding]; other site
926570010121	homodimer interface [polypeptide binding]; other site
926570010122	active site
926570010123	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
926570010124	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926570010125	OsmC-like protein; Region: OsmC; cl00767
926570010126	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
926570010127	active site
926570010128	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
926570010129	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
926570010130	polyhydroxyalkanoate depolymerase, intracellular; Region: PHB_depoly_PhaZ; TIGR01849
926570010131	PHB de-polymerase C-terminus; Region: PHB_depo_C; pfam06850
926570010132	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
926570010133	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
926570010134	CoA-binding site [chemical binding]; other site
926570010135	ATP-binding [chemical binding]; other site
926570010136	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
926570010137	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
926570010138	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
926570010139	shikimate binding site; other site
926570010140	NAD(P) binding site [chemical binding]; other site
926570010141	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570010142	NAD(P) binding site [chemical binding]; other site
926570010143	active site
926570010144	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570010145	DsbA family, 2-hydroxychromene-2-carboxylate (HCCA) isomerase subfamily; HCCA isomerase is a glutathione (GSH) dependent enzyme involved in the naphthalene catabolic pathway. It converts HCCA, a hemiketal formed spontaneously after ring cleavage of 1; Region: DsbA_HCCA_Iso; cd03022
926570010146	putative catalytic residue [active]
926570010147	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
926570010148	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
926570010149	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
926570010150	putative active site [active]
926570010151	putative substrate binding site [chemical binding]; other site
926570010152	putative cosubstrate binding site; other site
926570010153	catalytic site [active]
926570010154	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
926570010155	active site
926570010156	catalytic site [active]
926570010157	substrate binding site [chemical binding]; other site
926570010158	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
926570010159	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926570010160	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
926570010161	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
926570010162	Potassium binding sites [ion binding]; other site
926570010163	Cesium cation binding sites [ion binding]; other site
926570010164	seryl-tRNA synthetase; Provisional; Region: PRK05431
926570010165	agmatinase; Region: agmatinase; TIGR01230
926570010166	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
926570010167	oligomer interface [polypeptide binding]; other site
926570010168	putative active site [active]
926570010169	Mn binding site [ion binding]; other site
926570010170	amidase; Provisional; Region: PRK07056
926570010171	Amidase; Region: Amidase; cl11426
926570010172	Fumarylacetoacetate (FAA) hydrolase family protein [General function prediction only]; Region: COG3970
926570010173	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
926570010174	Lysine efflux permease [General function prediction only]; Region: COG1279
926570010175	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
926570010176	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570010177	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926570010178	dimerization interface [polypeptide binding]; other site
926570010179	Predicted integral membrane protein (DUF2189); Region: DUF2189; cl02291
926570010180	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926570010181	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926570010182	active site
926570010183	catalytic tetrad [active]
926570010184	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570010185	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570010186	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
926570010187	putative effector binding pocket; other site
926570010188	putative dimerization interface [polypeptide binding]; other site
926570010189	Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853
926570010190	3-hydroxyacyl-CoA dehydrogenase; Validated; Region: PRK06129
926570010191	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
926570010192	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
926570010193	Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type I periplasmic binding protein superfamily; Region: PBP1_ABC_sugar_binding_like_1; cd06300
926570010194	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570010195	putative ligand binding site [chemical binding]; other site
926570010196	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570010197	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570010198	Walker A/P-loop; other site
926570010199	ATP binding site [chemical binding]; other site
926570010200	Q-loop/lid; other site
926570010201	ABC transporter signature motif; other site
926570010202	Walker B; other site
926570010203	D-loop; other site
926570010204	H-loop/switch region; other site
926570010205	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570010206	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570010207	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570010208	TM-ABC transporter signature motif; other site
926570010209	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570010210	TM-ABC transporter signature motif; other site
926570010211	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
926570010212	GDP-Fucose binding site [chemical binding]; other site
926570010213	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
926570010214	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
926570010215	GDP-binding site [chemical binding]; other site
926570010216	ACT binding site; other site
926570010217	IMP binding site; other site
926570010218	Histidyl-tRNA synthetase; Region: tRNA-synt_His; pfam13393
926570010219	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926570010220	motif 1; other site
926570010221	dimer interface [polypeptide binding]; other site
926570010222	active site
926570010223	motif 2; other site
926570010224	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926570010225	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
926570010226	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
926570010227	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
926570010228	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570010229	Walker A motif; other site
926570010230	ATP binding site [chemical binding]; other site
926570010231	Walker B motif; other site
926570010232	arginine finger; other site
926570010233	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
926570010234	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
926570010235	Large subunit of methanol dehydrogenase (moxF); Region: PQQ_MDH; cd10278
926570010236	Trp docking motif [polypeptide binding]; other site
926570010237	dimer interface [polypeptide binding]; other site
926570010238	active site
926570010239	small subunit binding site [polypeptide binding]; other site
926570010240	quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein; Region: ABC_peri_MoxJ_2; TIGR03871
926570010241	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926570010242	substrate binding pocket [chemical binding]; other site
926570010243	membrane-bound complex binding site; other site
926570010244	hinge residues; other site
926570010245	Cytochrome c; Region: Cytochrom_C; cl11414
926570010246	c-type cytochrome, methanol metabolism-related; Region: 4cys_cytochr; TIGR03874
926570010247	glutathione-dependent formaldehyde-activating enzyme; Provisional; Region: PRK05417
926570010248	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
926570010249	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
926570010250	substrate binding site [chemical binding]; other site
926570010251	catalytic Zn binding site [ion binding]; other site
926570010252	NAD binding site [chemical binding]; other site
926570010253	structural Zn binding site [ion binding]; other site
926570010254	dimer interface [polypeptide binding]; other site
926570010255	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
926570010256	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
926570010257	N-terminal plug; other site
926570010258	ligand-binding site [chemical binding]; other site
926570010259	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
926570010260	FAD binding domain; Region: FAD_binding_4; pfam01565
926570010261	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926570010262	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
926570010263	Trp docking motif [polypeptide binding]; other site
926570010264	active site
926570010265	Cytochrome c; Region: Cytochrom_C; pfam00034
926570010266	sulfite reductase subunit beta; Provisional; Region: PRK13504
926570010267	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
926570010268	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
926570010269	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
926570010270	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
926570010271	Active Sites [active]
926570010272	sulfite reductase [NADPH] flavoprotein, alpha-component; Region: cysJ; TIGR01931
926570010273	Flavodoxin; Region: Flavodoxin_1; pfam00258
926570010274	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
926570010275	FAD binding pocket [chemical binding]; other site
926570010276	FAD binding motif [chemical binding]; other site
926570010277	catalytic residues [active]
926570010278	NAD binding pocket [chemical binding]; other site
926570010279	phosphate binding motif [ion binding]; other site
926570010280	beta-alpha-beta structure motif; other site
926570010281	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
926570010282	active site
926570010283	SAM binding site [chemical binding]; other site
926570010284	homodimer interface [polypeptide binding]; other site
926570010285	Putative NAD(P)-binding; Region: NAD_binding_7; cl17660
926570010286	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926570010287	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570010288	putative DNA binding site [nucleotide binding]; other site
926570010289	putative Zn2+ binding site [ion binding]; other site
926570010290	AsnC family; Region: AsnC_trans_reg; pfam01037
926570010291	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
926570010292	MPT binding site; other site
926570010293	trimer interface [polypeptide binding]; other site
926570010294	Protein of unknown function (DUF1295); Region: DUF1295; cl17837
926570010295	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
926570010296	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570010297	S-adenosylmethionine binding site [chemical binding]; other site
926570010298	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570010299	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570010300	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570010301	putative DNA binding site [nucleotide binding]; other site
926570010302	putative Zn2+ binding site [ion binding]; other site
926570010303	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
926570010304	ArsC family; Region: ArsC; pfam03960
926570010305	catalytic residues [active]
926570010306	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
926570010307	arsenical pump membrane protein; Provisional; Region: PRK15445
926570010308	transmembrane helices; other site
926570010309	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926570010310	DNA binding site [nucleotide binding]
926570010311	active site
926570010312	Int/Topo IB signature motif; other site
926570010313	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
926570010314	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570010315	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
926570010316	catalytic residues [active]
926570010317	catalytic nucleophile [active]
926570010318	Recombinase; Region: Recombinase; pfam07508
926570010319	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926570010320	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570010321	active site
926570010322	phosphorylation site [posttranslational modification]
926570010323	intermolecular recognition site; other site
926570010324	dimerization interface [polypeptide binding]; other site
926570010325	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570010326	DNA binding site [nucleotide binding]
926570010327	GTP cyclohydrolase; Provisional; Region: PRK08815
926570010328	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
926570010329	dimerization interface [polypeptide binding]; other site
926570010330	active site
926570010331	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3786
926570010332	Septum formation initiator; Region: DivIC; cl17659
926570010333	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
926570010334	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926570010335	tetramer interface [polypeptide binding]; other site
926570010336	TPP-binding site [chemical binding]; other site
926570010337	heterodimer interface [polypeptide binding]; other site
926570010338	phosphorylation loop region [posttranslational modification]
926570010339	pyruvate dehydrogenase subunit beta; Provisional; Region: PRK11892
926570010340	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926570010341	E3 interaction surface; other site
926570010342	lipoyl attachment site [posttranslational modification]; other site
926570010343	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
926570010344	alpha subunit interface [polypeptide binding]; other site
926570010345	TPP binding site [chemical binding]; other site
926570010346	heterodimer interface [polypeptide binding]; other site
926570010347	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926570010348	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926570010349	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
926570010350	E3 interaction surface; other site
926570010351	lipoyl attachment site [posttranslational modification]; other site
926570010352	e3 binding domain; Region: E3_binding; pfam02817
926570010353	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926570010354	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926570010355	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
926570010356	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926570010357	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926570010358	lipoyl synthase; Provisional; Region: PRK05481
926570010359	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
926570010360	putative coenzyme Q binding site [chemical binding]; other site
926570010361	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926570010362	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
926570010363	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570010364	catalytic residue [active]
926570010365	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
926570010366	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570010367	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570010368	Predicted flavoprotein [General function prediction only]; Region: COG0431
926570010369	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
926570010370	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926570010371	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926570010372	active site
926570010373	catalytic tetrad [active]
926570010374	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570010375	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570010376	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_3; cd08436
926570010377	putative dimerization interface [polypeptide binding]; other site
926570010378	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
926570010379	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
926570010380	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
926570010381	putative valine binding site [chemical binding]; other site
926570010382	dimer interface [polypeptide binding]; other site
926570010383	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
926570010384	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK09107
926570010385	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926570010386	PYR/PP interface [polypeptide binding]; other site
926570010387	dimer interface [polypeptide binding]; other site
926570010388	TPP binding site [chemical binding]; other site
926570010389	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926570010390	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
926570010391	TPP-binding site [chemical binding]; other site
926570010392	dimer interface [polypeptide binding]; other site
926570010393	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
926570010394	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
926570010395	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
926570010396	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570010397	motif II; other site
926570010398	CoA binding domain; Region: CoA_binding; cl17356
926570010399	Exo-beta-1,3-glucanase [Carbohydrate transport and metabolism]; Region: COG5309
926570010400	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
926570010401	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
926570010402	Phasin protein; Region: Phasin_2; pfam09361
926570010403	Uncharacterized conserved protein [Function unknown]; Region: COG2127
926570010404	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926570010405	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926570010406	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
926570010407	DNA-binding site [nucleotide binding]; DNA binding site
926570010408	RNA-binding motif; other site
926570010409	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
926570010410	DNA polymerase IV; Provisional; Region: PRK02794
926570010411	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
926570010412	active site
926570010413	DNA binding site [nucleotide binding]
926570010414	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
926570010415	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
926570010416	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
926570010417	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
926570010418	structural tetrad; other site
926570010419	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
926570010420	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
926570010421	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926570010422	PGAP1-like protein; Region: PGAP1; pfam07819
926570010423	acyl-CoA esterase; Provisional; Region: PRK10673
926570010424	EVE domain; Region: EVE; pfam01878
926570010425	YCII-related domain; Region: YCII; cl00999
926570010426	heme exporter protein CcmC; Region: ccmC; TIGR01191
926570010427	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13254
926570010428	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
926570010429	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926570010430	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926570010431	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
926570010432	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
926570010433	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
926570010434	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
926570010435	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
926570010436	Cl- selectivity filter; other site
926570010437	Cl- binding residues [ion binding]; other site
926570010438	pore gating glutamate residue; other site
926570010439	dimer interface [polypeptide binding]; other site
926570010440	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
926570010441	hypothetical protein; Validated; Region: PRK07586
926570010442	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926570010443	PYR/PP interface [polypeptide binding]; other site
926570010444	dimer interface [polypeptide binding]; other site
926570010445	TPP binding site [chemical binding]; other site
926570010446	Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002
926570010447	TPP-binding site [chemical binding]; other site
926570010448	dimer interface [polypeptide binding]; other site
926570010449	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
926570010450	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
926570010451	ligand binding site [chemical binding]; other site
926570010452	HrpA-like helicases [DNA replication, recombination, and repair]; Region: HrpA; COG1643
926570010453	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926570010454	ATP binding site [chemical binding]; other site
926570010455	putative Mg++ binding site [ion binding]; other site
926570010456	helicase superfamily c-terminal domain; Region: HELICc; smart00490
926570010457	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
926570010458	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
926570010459	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
926570010460	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
926570010461	DsbD alpha interface [polypeptide binding]; other site
926570010462	catalytic residues [active]
926570010463	Cytochrome c; Region: Cytochrom_C; cl11414
926570010464	Cytochrome c; Region: Cytochrom_C; cl11414
926570010465	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926570010466	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926570010467	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
926570010468	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
926570010469	NAD(P) binding site [chemical binding]; other site
926570010470	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
926570010471	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570010472	Walker A/P-loop; other site
926570010473	ATP binding site [chemical binding]; other site
926570010474	Q-loop/lid; other site
926570010475	ABC transporter signature motif; other site
926570010476	Walker B; other site
926570010477	D-loop; other site
926570010478	H-loop/switch region; other site
926570010479	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
926570010480	Permease; Region: Permease; pfam02405
926570010481	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
926570010482	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
926570010483	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926570010484	catalytic residue [active]
926570010485	EcsC protein family; Region: EcsC; pfam12787
926570010486	replicative DNA helicase; Provisional; Region: PRK09165
926570010487	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
926570010488	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
926570010489	Walker A motif; other site
926570010490	ATP binding site [chemical binding]; other site
926570010491	Walker B motif; other site
926570010492	DNA binding loops [nucleotide binding]
926570010493	Protein of unknown function (DUF1810); Region: DUF1810; pfam08837
926570010494	RbsD / FucU transport protein family; Region: RbsD_FucU; cl00809
926570010495	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926570010496	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
926570010497	substrate binding site [chemical binding]; other site
926570010498	dimer interface [polypeptide binding]; other site
926570010499	ATP binding site [chemical binding]; other site
926570010500	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
926570010501	FOG: CBS domain [General function prediction only]; Region: COG0517
926570010502	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623
926570010503	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
926570010504	substrate binding site [chemical binding]; other site
926570010505	ATP binding site [chemical binding]; other site
926570010506	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
926570010507	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
926570010508	active site
926570010509	FMN binding site [chemical binding]; other site
926570010510	substrate binding site [chemical binding]; other site
926570010511	homotetramer interface [polypeptide binding]; other site
926570010512	catalytic residue [active]
926570010513	LexA repressor; Validated; Region: PRK00215
926570010514	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
926570010515	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
926570010516	Catalytic site [active]
926570010517	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
926570010518	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
926570010519	putative metal binding site [ion binding]; other site
926570010520	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
926570010521	HSP70 interaction site [polypeptide binding]; other site
926570010522	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
926570010523	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
926570010524	amidase catalytic site [active]
926570010525	Zn binding residues [ion binding]; other site
926570010526	substrate binding site [chemical binding]; other site
926570010527	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
926570010528	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570010529	ATP binding site [chemical binding]; other site
926570010530	Mg2+ binding site [ion binding]; other site
926570010531	G-X-G motif; other site
926570010532	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
926570010533	anchoring element; other site
926570010534	dimer interface [polypeptide binding]; other site
926570010535	ATP binding site [chemical binding]; other site
926570010536	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
926570010537	active site
926570010538	putative metal-binding site [ion binding]; other site
926570010539	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
926570010540	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
926570010541	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570010542	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
926570010543	dimerization interface [polypeptide binding]; other site
926570010544	substrate binding pocket [chemical binding]; other site
926570010545	Predicted permeases [General function prediction only]; Region: COG0679
926570010546	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
926570010547	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
926570010548	metal binding site [ion binding]; metal-binding site
926570010549	active site
926570010550	I-site; other site
926570010551	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
926570010552	Uncharacterized conserved protein [Function unknown]; Region: COG3791
926570010553	Putative cyclase; Region: Cyclase; cl00814
926570010554	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570010555	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570010556	non-specific DNA binding site [nucleotide binding]; other site
926570010557	salt bridge; other site
926570010558	sequence-specific DNA binding site [nucleotide binding]; other site
926570010559	Smr domain; Region: Smr; pfam01713
926570010560	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
926570010561	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
926570010562	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
926570010563	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926570010564	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
926570010565	translocation protein TolB; Provisional; Region: tolB; PRK05137
926570010566	TolB amino-terminal domain; Region: TolB_N; pfam04052
926570010567	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926570010568	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
926570010569	TolR protein; Region: tolR; TIGR02801
926570010570	TolQ protein; Region: tolQ; TIGR02796
926570010571	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
926570010572	active site
926570010573	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
926570010574	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570010575	Walker A motif; other site
926570010576	ATP binding site [chemical binding]; other site
926570010577	Walker B motif; other site
926570010578	arginine finger; other site
926570010579	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
926570010580	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
926570010581	RuvA N terminal domain; Region: RuvA_N; pfam01330
926570010582	Holliday junction resolvase; Reviewed; Region: ruvC; PRK00039
926570010583	active site
926570010584	putative DNA-binding cleft [nucleotide binding]; other site
926570010585	dimer interface [polypeptide binding]; other site
926570010586	hypothetical protein; Validated; Region: PRK00110
926570010587	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570010588	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570010589	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570010590	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570010591	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570010592	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926570010593	putative substrate translocation pore; other site
926570010594	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
926570010595	Bacterial phosphonate metabolism protein (PhnH); Region: PhnH; pfam05845
926570010596	Bacterial phosphonate metabolism protein (PhnI); Region: PhnI; pfam05861
926570010597	Phosphonate metabolism protein PhnJ; Region: PhnJ; pfam06007
926570010598	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
926570010599	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926570010600	Walker A/P-loop; other site
926570010601	ATP binding site [chemical binding]; other site
926570010602	Q-loop/lid; other site
926570010603	ABC transporter signature motif; other site
926570010604	Walker B; other site
926570010605	D-loop; other site
926570010606	H-loop/switch region; other site
926570010607	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926570010608	phosphonate C-P lyase system protein PhnL; Region: CP_lyasePhnL; TIGR02324
926570010609	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570010610	Walker A/P-loop; other site
926570010611	ATP binding site [chemical binding]; other site
926570010612	Q-loop/lid; other site
926570010613	ABC transporter signature motif; other site
926570010614	Walker B; other site
926570010615	D-loop; other site
926570010616	H-loop/switch region; other site
926570010617	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
926570010618	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570010619	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926570010620	active site
926570010621	putative phosphonate metabolism protein; Region: Phn_opern_protn; TIGR03223
926570010622	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
926570010623	active site
926570010624	phosphonates metabolism transcriptional regulator PhnF; Region: C_P_lyase_phnF; TIGR02325
926570010625	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926570010626	DNA-binding site [nucleotide binding]; DNA binding site
926570010627	UTRA domain; Region: UTRA; pfam07702
926570010628	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570010629	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926570010630	active site
926570010631	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926570010632	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926570010633	Probable Catalytic site; other site
926570010634	metal-binding site
926570010635	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
926570010636	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
926570010637	23S rRNA binding site [nucleotide binding]; other site
926570010638	L21 binding site [polypeptide binding]; other site
926570010639	L13 binding site [polypeptide binding]; other site
926570010640	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
926570010641	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
926570010642	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926570010643	putative active site [active]
926570010644	putative metal binding site [ion binding]; other site
926570010645	conserved hypothetical protein, steroid delta-isomerase-related; Region: TIGR02096
926570010646	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
926570010647	Prostaglandin dehydrogenases; Region: PGDH; cd05288
926570010648	NAD(P) binding site [chemical binding]; other site
926570010649	substrate binding site [chemical binding]; other site
926570010650	dimer interface [polypeptide binding]; other site
926570010651	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570010652	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926570010653	Walker A/P-loop; other site
926570010654	ATP binding site [chemical binding]; other site
926570010655	Q-loop/lid; other site
926570010656	ABC transporter signature motif; other site
926570010657	Walker B; other site
926570010658	D-loop; other site
926570010659	H-loop/switch region; other site
926570010660	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570010661	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926570010662	Walker A/P-loop; other site
926570010663	ATP binding site [chemical binding]; other site
926570010664	Q-loop/lid; other site
926570010665	ABC transporter signature motif; other site
926570010666	Walker B; other site
926570010667	D-loop; other site
926570010668	H-loop/switch region; other site
926570010669	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926570010670	Periplasmic solute-binding domain of active transport proteins that belong to the type I periplasmic binding fold protein family; Region: PBP1_SBP_like_1; cd06327
926570010671	putative ligand binding site [chemical binding]; other site
926570010672	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926570010673	TM-ABC transporter signature motif; other site
926570010674	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926570010675	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926570010676	TM-ABC transporter signature motif; other site
926570010677	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
926570010678	Amidase; Region: Amidase; cl11426
926570010679	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
926570010680	Domain of unknown function (DUF3416); Region: DUF3416; pfam11896
926570010681	Alpha amylase catalytic domain found in GlgE-like proteins; Region: AmyAc_GlgE_like; cd11344
926570010682	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
926570010683	active site
926570010684	homodimer interface [polypeptide binding]; other site
926570010685	catalytic site [active]
926570010686	acceptor binding site [chemical binding]; other site
926570010687	trehalose synthase; Region: treS_nterm; TIGR02456
926570010688	Alpha amylase catalytic domain found in Trehalose synthetase; Region: AmyAc_TreS; cd11334
926570010689	active site
926570010690	catalytic site [active]
926570010691	trehalose synthase-fused probable maltokinase; Region: TreS_Cterm; TIGR02457
926570010692	Uncharacterized protein, probably involved in trehalose biosynthesis [Carbohydrate transport and metabolism]; Region: Ble; COG3281
926570010693	glycogen branching enzyme; Provisional; Region: PRK05402
926570010694	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
926570010695	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
926570010696	active site
926570010697	catalytic site [active]
926570010698	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
926570010699	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
926570010700	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
926570010701	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
926570010702	active site
926570010703	catalytic site [active]
926570010704	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
926570010705	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
926570010706	glycosyltransferase, TIGR04182 family; Region: glyco_TIGR04182
926570010707	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926570010708	Ligand binding site; other site
926570010709	Putative Catalytic site; other site
926570010710	DXD motif; other site
926570010711	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570010712	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570010713	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570010714	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570010715	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926570010716	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570010717	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570010718	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570010719	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570010720	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926570010721	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
926570010722	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570010723	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570010724	AAA ATPase domain; Region: AAA_16; pfam13191
926570010725	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
926570010726	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
926570010727	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
926570010728	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
926570010729	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
926570010730	heme bL binding site [chemical binding]; other site
926570010731	interchain domain interface [polypeptide binding]; other site
926570010732	intrachain domain interface; other site
926570010733	heme bH binding site [chemical binding]; other site
926570010734	Qo binding site; other site
926570010735	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
926570010736	5'-methylthioadenosine phosphorylase; Provisional; Region: PRK08931
926570010737	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
926570010738	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
926570010739	dimer interface [polypeptide binding]; other site
926570010740	decamer (pentamer of dimers) interface [polypeptide binding]; other site
926570010741	catalytic triad [active]
926570010742	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
926570010743	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
926570010744	Walker A/P-loop; other site
926570010745	ATP binding site [chemical binding]; other site
926570010746	Q-loop/lid; other site
926570010747	ABC transporter signature motif; other site
926570010748	Walker B; other site
926570010749	D-loop; other site
926570010750	H-loop/switch region; other site
926570010751	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
926570010752	PhoU domain; Region: PhoU; pfam01895
926570010753	PhoU domain; Region: PhoU; pfam01895
926570010754	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
926570010755	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570010756	active site
926570010757	phosphorylation site [posttranslational modification]
926570010758	intermolecular recognition site; other site
926570010759	dimerization interface [polypeptide binding]; other site
926570010760	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926570010761	DNA binding site [nucleotide binding]
926570010762	Protein of unknown function (DUF3311); Region: DUF3311; pfam11755
926570010763	Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591
926570010764	Na binding site [ion binding]; other site
926570010765	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
926570010766	Bacterial sugar transferase; Region: Bac_transf; pfam02397
926570010767	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
926570010768	putative PEP-CTERM system histidine kinase; Region: PEP_his_kin; TIGR02916
926570010769	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570010770	ATP binding site [chemical binding]; other site
926570010771	Mg2+ binding site [ion binding]; other site
926570010772	G-X-G motif; other site
926570010773	PEP-CTERM-box response regulator transcription factor; Region: PEP_resp_reg; TIGR02915
926570010774	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926570010775	active site
926570010776	phosphorylation site [posttranslational modification]
926570010777	intermolecular recognition site; other site
926570010778	dimerization interface [polypeptide binding]; other site
926570010779	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570010780	Walker A motif; other site
926570010781	ATP binding site [chemical binding]; other site
926570010782	Walker B motif; other site
926570010783	arginine finger; other site
926570010784	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
926570010785	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
926570010786	binding surface
926570010787	TPR motif; other site
926570010788	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
926570010789	binding surface
926570010790	TPR motif; other site
926570010791	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926570010792	TPR motif; other site
926570010793	O-Antigen ligase; Region: Wzy_C; cl04850
926570010794	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
926570010795	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570010796	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
926570010797	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
926570010798	polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Region: pepcterm_ChnLen; TIGR03007
926570010799	Chain length determinant protein; Region: Wzz; cl15801
926570010800	AAA domain; Region: AAA_31; pfam13614
926570010801	uncharacterized protein, PEP-CTERM system associated; Region: pepcterm_hypo_1; TIGR03016
926570010802	putative secretion ATPase, PEP-CTERM locus subfamily; Region: pepcterm_ATPase; TIGR03015
926570010803	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570010804	Walker A motif; other site
926570010805	ATP binding site [chemical binding]; other site
926570010806	Walker B motif; other site
926570010807	arginine finger; other site
926570010808	polysaccharide deacetylase family protein, PEP-CTERM locus subfamily; Region: pepcterm_polyde; TIGR03006
926570010809	Putative catalytic domain of uncharacterized prokaryotic polysaccharide deacetylases similar to bacterial PuuE allantoinases and Helicobacter pylori peptidoglycan deacetylase (HpPgdA); Region: CE4_PuuE_HpPgdA_like_2; cd10941
926570010810	putative active site [active]
926570010811	putative catalytic site [active]
926570010812	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
926570010813	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
926570010814	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
926570010815	Predicted membrane protein [Function unknown]; Region: COG4083; cl15694
926570010816	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
926570010817	Cupin domain; Region: Cupin_2; cl17218
926570010818	Transposase [DNA replication, recombination, and repair]; Region: COG5421
926570010819	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
926570010820	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570010821	Walker A motif; other site
926570010822	ATP binding site [chemical binding]; other site
926570010823	Walker B motif; other site
926570010824	arginine finger; other site
926570010825	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
926570010826	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926570010827	(2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233
926570010828	putative NAD(P) binding site [chemical binding]; other site
926570010829	catalytic Zn binding site [ion binding]; other site
926570010830	SnoaL-like domain; Region: SnoaL_2; pfam12680
926570010831	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
926570010832	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
926570010833	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
926570010834	TadE-like protein; Region: TadE; pfam07811
926570010835	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
926570010836	Domain of unknown function (DUF718); Region: DUF718; pfam05336
926570010837	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570010838	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570010839	TM-ABC transporter signature motif; other site
926570010840	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570010841	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926570010842	TM-ABC transporter signature motif; other site
926570010843	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926570010844	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926570010845	Walker A/P-loop; other site
926570010846	ATP binding site [chemical binding]; other site
926570010847	Q-loop/lid; other site
926570010848	ABC transporter signature motif; other site
926570010849	Walker B; other site
926570010850	D-loop; other site
926570010851	H-loop/switch region; other site
926570010852	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926570010853	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
926570010854	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926570010855	ligand binding site [chemical binding]; other site
926570010856	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926570010857	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
926570010858	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926570010859	L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype; Region: L_rham_iso_rhiz; TIGR02629
926570010860	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
926570010861	short chain dehydrogenase; Validated; Region: PRK08324
926570010862	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
926570010863	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570010864	NAD(P) binding site [chemical binding]; other site
926570010865	active site
926570010866	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
926570010867	N- and C-terminal domain interface [polypeptide binding]; other site
926570010868	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
926570010869	active site
926570010870	putative catalytic site [active]
926570010871	metal binding site [ion binding]; metal-binding site
926570010872	ATP binding site [chemical binding]; other site
926570010873	carbohydrate binding site [chemical binding]; other site
926570010874	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
926570010875	HAMP domain; Region: HAMP; pfam00672
926570010876	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
926570010877	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
926570010878	dimer interface [polypeptide binding]; other site
926570010879	putative CheW interface [polypeptide binding]; other site
926570010880	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
926570010881	30S subunit binding site; other site
926570010882	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
926570010883	DNA-binding site [nucleotide binding]; DNA binding site
926570010884	RNA-binding motif; other site
926570010885	DnaJ-class molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: CbpA; COG2214
926570010886	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
926570010887	HSP70 interaction site [polypeptide binding]; other site
926570010888	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
926570010889	substrate binding site [polypeptide binding]; other site
926570010890	dimer interface [polypeptide binding]; other site
926570010891	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
926570010892	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
926570010893	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
926570010894	Moco binding site; other site
926570010895	metal coordination site [ion binding]; other site
926570010896	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
926570010897	Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; Region: PRX_like2; cd02970
926570010898	putative catalytic residues [active]
926570010899	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926570010900	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570010901	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
926570010902	dimerization interface [polypeptide binding]; other site
926570010903	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
926570010904	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
926570010905	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
926570010906	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
926570010907	Walker A/P-loop; other site
926570010908	ATP binding site [chemical binding]; other site
926570010909	Q-loop/lid; other site
926570010910	ABC transporter signature motif; other site
926570010911	Walker B; other site
926570010912	D-loop; other site
926570010913	H-loop/switch region; other site
926570010914	TOBE domain; Region: TOBE_2; pfam08402
926570010915	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926570010916	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570010917	dimer interface [polypeptide binding]; other site
926570010918	conserved gate region; other site
926570010919	putative PBP binding loops; other site
926570010920	ABC-ATPase subunit interface; other site
926570010921	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926570010922	dimer interface [polypeptide binding]; other site
926570010923	conserved gate region; other site
926570010924	ABC-ATPase subunit interface; other site
926570010925	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926570010926	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926570010927	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
926570010928	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
926570010929	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570010930	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926570010931	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926570010932	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926570010933	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
926570010934	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926570010935	catalytic loop [active]
926570010936	iron binding site [ion binding]; other site
926570010937	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926570010938	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926570010939	MarR family; Region: MarR; pfam01047
926570010940	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926570010941	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926570010942	Coenzyme A binding pocket [chemical binding]; other site
926570010943	diaminobutyrate--2-oxoglutarate aminotransferase; Validated; Region: PRK09264
926570010944	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926570010945	inhibitor-cofactor binding pocket; inhibition site
926570010946	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570010947	catalytic residue [active]
926570010948	Ectoine synthase; Region: Ectoine_synth; pfam06339
926570010949	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
926570010950	aspartate kinase; Validated; Region: PRK09181
926570010951	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
926570010952	nucleotide binding site [chemical binding]; other site
926570010953	substrate binding site [chemical binding]; other site
926570010954	ACT domains located C-terminal to the catalytic domain of the aspartokinase of the ectoine (1,4,5,6-tetrahydro-2-methyl pyrimidine-4-carboxylate) biosynthetic pathway; Region: ACT_AK-Ectoine_1; cd04910
926570010955	allosteric regulatory residue; other site
926570010956	ACT domains located C-terminal to the catalytic domain of the aspartokinase of the ectoine (1,4,5,6-tetrahydro-2-methyl pyrimidine-4-carboxylate) biosynthetic pathway; Region: ACT_AK-Ectoine_2; cd04915
926570010957	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926570010958	putative substrate translocation pore; other site
926570010959	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
926570010960	mce related protein; Region: MCE; pfam02470
926570010961	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
926570010962	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926570010963	Walker A/P-loop; other site
926570010964	ATP binding site [chemical binding]; other site
926570010965	Q-loop/lid; other site
926570010966	ABC transporter signature motif; other site
926570010967	Walker B; other site
926570010968	D-loop; other site
926570010969	H-loop/switch region; other site
926570010970	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
926570010971	Permease; Region: Permease; pfam02405
926570010972	Integral membrane protein TerC family; Region: TerC; cl10468
926570010973	adenylosuccinate lyase; Provisional; Region: PRK07492
926570010974	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
926570010975	tetramer interface [polypeptide binding]; other site
926570010976	active site
926570010977	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
926570010978	NRDE protein; Region: NRDE; cl01315
926570010979	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
926570010980	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
926570010981	tetrameric interface [polypeptide binding]; other site
926570010982	NAD binding site [chemical binding]; other site
926570010983	catalytic residues [active]
926570010984	allantoate amidohydrolase; Reviewed; Region: PRK12893
926570010985	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
926570010986	active site
926570010987	metal binding site [ion binding]; metal-binding site
926570010988	dimer interface [polypeptide binding]; other site
926570010989	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
926570010990	SnoaL-like domain; Region: SnoaL_2; pfam12680
926570010991	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
926570010992	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926570010993	DsrE/DsrF-like family; Region: DrsE; cl00672
926570010994	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926570010995	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
926570010996	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926570010997	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07533
926570010998	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926570010999	NAD(P) binding site [chemical binding]; other site
926570011000	active site
926570011001	Poly-beta-hydroxybutyrate polymerase N terminal; Region: PHBC_N; pfam12551
926570011002	poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838
926570011003	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
926570011004	bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated; Region: PRK08190
926570011005	(R)-hydratase [(R)-specific enoyl-CoA hydratase] catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. (R)-hydratase contains a hot-dog fold similar to those of thioesterase...; Region: R_hydratase; cd03449
926570011006	dimer interaction site [polypeptide binding]; other site
926570011007	substrate-binding tunnel; other site
926570011008	active site
926570011009	catalytic site [active]
926570011010	substrate binding site [chemical binding]; other site
926570011011	phosphate acetyltransferase; Provisional; Region: PRK11890
926570011012	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
926570011013	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
926570011014	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
926570011015	Na binding site [ion binding]; other site
926570011016	Domain of unknown function (DUF4188); Region: DUF4188; pfam13826
926570011017	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926570011018	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926570011019	WHG domain; Region: WHG; pfam13305
926570011020	aldolase II superfamily protein; Provisional; Region: PRK07044
926570011021	intersubunit interface [polypeptide binding]; other site
926570011022	active site
926570011023	Zn2+ binding site [ion binding]; other site
926570011024	Phospholipid methyltransferase; Region: PEMT; cl17370
926570011025	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926570011026	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
926570011027	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
926570011028	Moco binding site; other site
926570011029	metal coordination site [ion binding]; other site
926570011030	Cytochrome c; Region: Cytochrom_C; pfam00034
926570011031	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
926570011032	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
926570011033	Sulfur oxidation protein SoxY; Region: SoxY; pfam13501
926570011034	Sulphur oxidation protein SoxZ; Region: SoxZ; pfam08770
926570011035	Cytochrome c [Energy production and conversion]; Region: COG3258
926570011036	Cytochrome c [Energy production and conversion]; Region: COG3258
926570011037	Thermus thermophilus SoxB and related proteins, N-terminal metallophosphatase domain; Region: MPP_SoxB_N; cd07411
926570011038	active site
926570011039	metal binding site [ion binding]; metal-binding site
926570011040	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
926570011041	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
926570011042	DsrE/DsrF-like family; Region: DrsE; pfam02635
926570011043	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
926570011044	alpha-L-glutamate ligases, RimK family; Region: rimK_fam; TIGR00768
926570011045	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
926570011046	Domain of unknown function DUF302; Region: DUF302; pfam03625
926570011047	acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397
926570011048	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
926570011049	propionate/acetate kinase; Provisional; Region: PRK12379
926570011050	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
926570011051	cyclase homology domain; Region: CHD; cd07302
926570011052	nucleotidyl binding site; other site
926570011053	metal binding site [ion binding]; metal-binding site
926570011054	dimer interface [polypeptide binding]; other site
926570011055	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
926570011056	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
926570011057	phosphopeptide binding site; other site
926570011058	glutamine synthetase; Provisional; Region: glnA; PRK09469
926570011059	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
926570011060	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
926570011061	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
926570011062	Nitrogen regulatory protein P-II; Region: P-II; smart00938
926570011063	hypothetical protein; Provisional; Region: PRK08912
926570011064	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926570011065	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926570011066	homodimer interface [polypeptide binding]; other site
926570011067	catalytic residue [active]
926570011068	nitrilase; Region: PLN02798
926570011069	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
926570011070	putative active site [active]
926570011071	catalytic triad [active]
926570011072	dimer interface [polypeptide binding]; other site
926570011073	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
926570011074	ATP-NAD kinase; Region: NAD_kinase; pfam01513
926570011075	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
926570011076	malate dehydrogenase; Provisional; Region: PRK05442
926570011077	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
926570011078	NAD(P) binding site [chemical binding]; other site
926570011079	dimer interface [polypeptide binding]; other site
926570011080	malate binding site [chemical binding]; other site
926570011081	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926570011082	LysR family transcriptional regulator; Provisional; Region: PRK14997
926570011083	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
926570011084	putative effector binding pocket; other site
926570011085	dimerization interface [polypeptide binding]; other site
926570011086	Protein of unknown function (DUF796); Region: DUF796; pfam05638
926570011087	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
926570011088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570011089	Walker A motif; other site
926570011090	ATP binding site [chemical binding]; other site
926570011091	Walker B motif; other site
926570011092	arginine finger; other site
926570011093	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570011094	Walker A motif; other site
926570011095	ATP binding site [chemical binding]; other site
926570011096	Walker B motif; other site
926570011097	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
926570011098	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
926570011099	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
926570011100	Protein of unknown function (DUF877); Region: DUF877; pfam05943
926570011101	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
926570011102	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
926570011103	Protein of unknown function (DUF877); Region: DUF877; pfam05943
926570011104	Protein of unknown function (DUF770); Region: DUF770; pfam05591
926570011105	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
926570011106	Cytomegalovirus UL84 protein; Region: Cytomega_UL84; pfam06284
926570011107	ImpE protein; Region: ImpE; pfam07024
926570011108	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
926570011109	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
926570011110	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
926570011111	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
926570011112	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926570011113	S-adenosylmethionine binding site [chemical binding]; other site
926570011114	Predicted methyltransferase regulatory domain; Region: MethyTransf_Reg; pfam10119
926570011115	cyanophycin synthetase; Provisional; Region: PRK14016
926570011116	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
926570011117	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
926570011118	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
926570011119	putative acyl-acceptor binding pocket; other site
926570011120	Uncharacterized conserved protein [Function unknown]; Region: COG1434
926570011121	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
926570011122	putative active site [active]
926570011123	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
926570011124	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
926570011125	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926570011126	Walker A/P-loop; other site
926570011127	ATP binding site [chemical binding]; other site
926570011128	Q-loop/lid; other site
926570011129	ABC transporter signature motif; other site
926570011130	Walker B; other site
926570011131	D-loop; other site
926570011132	H-loop/switch region; other site
926570011133	zinc-ribbon domain; Region: zinc_ribbon_5; pfam13719
926570011134	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
926570011135	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
926570011136	active site
926570011137	dimer interface [polypeptide binding]; other site
926570011138	heat shock protein 90; Provisional; Region: PRK05218
926570011139	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926570011140	ATP binding site [chemical binding]; other site
926570011141	Mg2+ binding site [ion binding]; other site
926570011142	G-X-G motif; other site
926570011143	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
926570011144	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926570011145	nucleotide binding region [chemical binding]; other site
926570011146	ATP-binding site [chemical binding]; other site
926570011147	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926570011148	RNA binding surface [nucleotide binding]; other site
926570011149	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
926570011150	4Fe-4S binding domain; Region: Fer4; cl02805
926570011151	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
926570011152	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
926570011153	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
926570011154	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
926570011155	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926570011156	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926570011157	Walker A/P-loop; other site
926570011158	ATP binding site [chemical binding]; other site
926570011159	Q-loop/lid; other site
926570011160	ABC transporter signature motif; other site
926570011161	Walker B; other site
926570011162	D-loop; other site
926570011163	H-loop/switch region; other site
926570011164	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926570011165	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926570011166	TM-ABC transporter signature motif; other site
926570011167	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926570011168	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926570011169	Walker A/P-loop; other site
926570011170	ATP binding site [chemical binding]; other site
926570011171	Q-loop/lid; other site
926570011172	ABC transporter signature motif; other site
926570011173	Walker B; other site
926570011174	D-loop; other site
926570011175	H-loop/switch region; other site
926570011176	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926570011177	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926570011178	TM-ABC transporter signature motif; other site
926570011179	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
926570011180	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926570011181	dimerization interface [polypeptide binding]; other site
926570011182	ligand binding site [chemical binding]; other site
926570011183	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
926570011184	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
926570011185	N-terminal plug; other site
926570011186	ligand-binding site [chemical binding]; other site
926570011187	2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428
926570011188	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926570011189	motif II; other site
926570011190	GST_N family, Beta etherase LigE subfamily; composed of proteins similar to Sphingomonas paucimobilis beta etherase, LigE, a GST-like protein that catalyzes the cleavage of the beta-aryl ether linkages present in low-moleculer weight lignins using GSH as...; Region: GST_N_etherase_LigE; cd03038
926570011191	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
926570011192	putative C-terminal domain interface [polypeptide binding]; other site
926570011193	putative GSH binding site (G-site) [chemical binding]; other site
926570011194	putative dimer interface [polypeptide binding]; other site
926570011195	C-terminal, alpha helical domain of Beta etherase LigE; Region: GST_C_etherase_LigE; cd03202
926570011196	putative dimer interface [polypeptide binding]; other site
926570011197	putative N-terminal domain interface [polypeptide binding]; other site
926570011198	putative substrate binding pocket (H-site) [chemical binding]; other site
926570011199	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926570011200	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926570011201	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
926570011202	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
926570011203	catalytic residues [active]
926570011204	O-succinylhomoserine sulfhydrylase; Reviewed; Region: PRK07504
926570011205	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926570011206	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926570011207	catalytic residue [active]
926570011208	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
926570011209	replication initiation protein RepC; Provisional; Region: PRK13824
926570011210	Replication protein C N-terminal domain; Region: RP-C; pfam03428
926570011211	Replication protein C C-terminal region; Region: RP-C_C; pfam11800
926570011212	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570011213	non-specific DNA binding site [nucleotide binding]; other site
926570011214	salt bridge; other site
926570011215	sequence-specific DNA binding site [nucleotide binding]; other site
926570011216	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
926570011217	ParA-like protein; Provisional; Region: PHA02518
926570011218	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570011219	Magnesium ion binding site [ion binding]; other site
926570011220	Ribbon-helix-helix domain; Region: RHH_3; pfam12651
926570011221	Nuclease-related domain; Region: NERD; pfam08378
926570011222	Rv0623-like transcription factor; Region: PSK_trans_fac; pfam07704
926570011223	PIN domain of the VapC-like UPF0110 protein Mb0640 and homologs; Region: PIN_UPF0110; cd09871
926570011224	putative active site [active]
926570011225	VbhA antitoxin and related proteins; Region: VbhA_like; cd11586
926570011226	FIC domain binding interface [polypeptide binding]; other site
926570011227	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
926570011228	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
926570011229	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
926570011230	arsenical pump membrane protein; Provisional; Region: PRK15445
926570011231	transmembrane helices; other site
926570011232	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
926570011233	ArsC family; Region: ArsC; pfam03960
926570011234	catalytic residues [active]
926570011235	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
926570011236	Low molecular weight phosphatase family; Region: LMWPc; cd00115
926570011237	active site
926570011238	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926570011239	putative DNA binding site [nucleotide binding]; other site
926570011240	putative Zn2+ binding site [ion binding]; other site
926570011241	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
926570011242	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
926570011243	iron-sulfur cluster [ion binding]; other site
926570011244	[2Fe-2S] cluster binding site [ion binding]; other site
926570011245	arsenite oxidase, large subunit; Region: arsenite_ox_L; TIGR02693
926570011246	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926570011247	molybdopterin cofactor binding site; other site
926570011248	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
926570011249	molybdopterin cofactor binding site; other site
926570011250	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570011251	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570011252	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
926570011253	transposase/IS protein; Provisional; Region: PRK09183
926570011254	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926570011255	Walker A motif; other site
926570011256	ATP binding site [chemical binding]; other site
926570011257	Walker B motif; other site
926570011258	arginine finger; other site
926570011259	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926570011260	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
926570011261	DNA binding residues [nucleotide binding]
926570011262	Integrase core domain; Region: rve; pfam00665
926570011263	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
926570011264	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926570011265	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926570011266	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
926570011267	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
926570011268	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
926570011269	active site
926570011270	LssY C-terminus; Region: LssY_C; pfam14067
926570011271	Transposase domain (DUF772); Region: DUF772; pfam05598
926570011272	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
926570011273	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570011274	non-specific DNA binding site [nucleotide binding]; other site
926570011275	salt bridge; other site
926570011276	sequence-specific DNA binding site [nucleotide binding]; other site
926570011277	plasma-membrane proton-efflux P-type ATPase; Region: ATPase-IIIA_H; TIGR01647
926570011278	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926570011279	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
926570011280	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
926570011281	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
926570011282	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
926570011283	Ti-type conjugative transfer relaxase TraA; Region: TraA_Ti; TIGR02768
926570011284	AAA domain; Region: AAA_30; pfam13604
926570011285	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
926570011286	Q-loop/lid; other site
926570011287	ABC transporter signature motif; other site
926570011288	Walker B; other site
926570011289	D-loop; other site
926570011290	H-loop/switch region; other site
926570011291	Protein of unknown function (DUF1156); Region: DUF1156; pfam06634
926570011292	Adenine-specific DNA methylase containing a Zn-ribbon [DNA replication, recombination, and repair]; Region: COG1743
926570011293	DNA methylase; Region: N6_N4_Mtase; cl17433
926570011294	Methyltransferase domain; Region: Methyltransf_26; pfam13659
926570011295	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570011296	multiple promoter invertase; Provisional; Region: mpi; PRK13413
926570011297	catalytic residues [active]
926570011298	catalytic nucleophile [active]
926570011299	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570011300	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570011301	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570011302	Synaptic Site I dimer interface [polypeptide binding]; other site
926570011303	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570011304	DNA-binding interface [nucleotide binding]; DNA binding site
926570011305	Uncharacterized conserved protein [Function unknown]; Region: COG2135
926570011306	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
926570011307	Catalytic site [active]
926570011308	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
926570011309	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
926570011310	active site
926570011311	DNA binding site [nucleotide binding]
926570011312	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
926570011313	MobA/MobL family; Region: MobA_MobL; pfam03389
926570011314	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
926570011315	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
926570011316	Walker A motif; other site
926570011317	ATP binding site [chemical binding]; other site
926570011318	Walker B motif; other site
926570011319	Domain of unknown function DUF29; Region: DUF29; pfam01724
926570011320	Helix-turn-helix domain; Region: HTH_36; pfam13730
926570011321	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
926570011322	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
926570011323	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570011324	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570011325	catalytic residues [active]
926570011326	catalytic nucleophile [active]
926570011327	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570011328	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570011329	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570011330	Synaptic Site I dimer interface [polypeptide binding]; other site
926570011331	DNA binding site [nucleotide binding]
926570011332	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570011333	DNA-binding interface [nucleotide binding]; DNA binding site
926570011334	type IV secretion system protein VirB11; Provisional; Region: PRK13851
926570011335	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
926570011336	Walker A motif; other site
926570011337	hexamer interface [polypeptide binding]; other site
926570011338	ATP binding site [chemical binding]; other site
926570011339	Walker B motif; other site
926570011340	Bacterial conjugation TrbI-like protein; Region: TrbI; cl04242
926570011341	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
926570011342	VirB7 interaction site; other site
926570011343	VirB8 protein; Region: VirB8; cl01500
926570011344	type IV secretion system lipoprotein VirB7; Provisional; Region: PRK13859
926570011345	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
926570011346	P-type DNA transfer protein VirB5; Region: VirB5; TIGR02791
926570011347	Type IV secretion system proteins; Region: T4SS; pfam07996
926570011348	type IV secretion system protein VirB4; Provisional; Region: PRK13853
926570011349	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
926570011350	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
926570011351	TrbC/VIRB2 family; Region: TrbC; cl01583
926570011352	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926570011353	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926570011354	catalytic residue [active]
926570011355	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926570011356	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926570011357	non-specific DNA binding site [nucleotide binding]; other site
926570011358	salt bridge; other site
926570011359	sequence-specific DNA binding site [nucleotide binding]; other site
926570011360	replication initiation protein RepC; Provisional; Region: PRK13824
926570011361	Replication protein C N-terminal domain; Region: RP-C; pfam03428
926570011362	Replication protein C C-terminal region; Region: RP-C_C; pfam11800
926570011363	conjugal transfer relaxosome component TraJ; Provisional; Region: PRK13877
926570011364	Antitoxin of toxin-antitoxin stability system N-terminal; Region: RelB_N; pfam12910
926570011365	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
926570011366	putative active site [active]
926570011367	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901
926570011368	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
926570011369	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
926570011370	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570011371	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570011372	catalytic residues [active]
926570011373	catalytic nucleophile [active]
926570011374	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570011375	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570011376	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570011377	Synaptic Site I dimer interface [polypeptide binding]; other site
926570011378	DNA binding site [nucleotide binding]
926570011379	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570011380	DNA-binding interface [nucleotide binding]; DNA binding site
926570011381	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
926570011382	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
926570011383	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570011384	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570011385	catalytic residues [active]
926570011386	catalytic nucleophile [active]
926570011387	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570011388	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570011389	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570011390	Synaptic Site I dimer interface [polypeptide binding]; other site
926570011391	DNA binding site [nucleotide binding]
926570011392	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570011393	DNA-binding interface [nucleotide binding]; DNA binding site
926570011394	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
926570011395	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
926570011396	oligomeric interface; other site
926570011397	putative active site [active]
926570011398	homodimer interface [polypeptide binding]; other site
926570011399	Ti-type conjugative transfer relaxase TraA; Region: TraA_Ti; TIGR02768
926570011400	MobA/MobL family; Region: MobA_MobL; pfam03389
926570011401	AAA domain; Region: AAA_30; pfam13604
926570011402	Family description; Region: UvrD_C_2; pfam13538
926570011403	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
926570011404	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
926570011405	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
926570011406	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
926570011407	Walker A/P-loop; other site
926570011408	ATP binding site [chemical binding]; other site
926570011409	Q-loop/lid; other site
926570011410	ABC transporter signature motif; other site
926570011411	Walker B; other site
926570011412	D-loop; other site
926570011413	H-loop/switch region; other site
926570011414	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
926570011415	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
926570011416	NAD binding site [chemical binding]; other site
926570011417	substrate binding site [chemical binding]; other site
926570011418	homodimer interface [polypeptide binding]; other site
926570011419	active site
926570011420	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
926570011421	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
926570011422	substrate binding site; other site
926570011423	tetramer interface; other site
926570011424	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
926570011425	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
926570011426	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
926570011427	NADP binding site [chemical binding]; other site
926570011428	active site
926570011429	putative substrate binding site [chemical binding]; other site
926570011430	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926570011431	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570011432	active site
926570011433	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570011434	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570011435	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926570011436	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
926570011437	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926570011438	Probable Catalytic site; other site
926570011439	metal-binding site
926570011440	Transposase domain (DUF772); Region: DUF772; pfam05598
926570011441	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926570011442	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926570011443	multiple promoter invertase; Provisional; Region: mpi; PRK13413
926570011444	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
926570011445	catalytic residues [active]
926570011446	catalytic nucleophile [active]
926570011447	Presynaptic Site I dimer interface [polypeptide binding]; other site
926570011448	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
926570011449	Synaptic Flat tetramer interface [polypeptide binding]; other site
926570011450	Synaptic Site I dimer interface [polypeptide binding]; other site
926570011451	DNA binding site [nucleotide binding]
926570011452	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
926570011453	DNA-binding interface [nucleotide binding]; DNA binding site
926570011454	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570011455	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570011456	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
926570011457	Uncharacterized conserved protein [Function unknown]; Region: COG2353
926570011458	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
926570011459	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
926570011460	catalytic residues [active]
926570011461	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
926570011462	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
926570011463	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
926570011464	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926570011465	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926570011466	P-loop; other site
926570011467	Magnesium ion binding site [ion binding]; other site
926570011468	Helix-turn-helix domain; Region: HTH_36; pfam13730
926570011469	helix-turn-helix, Psq domain; Region: HTH_psq; pfam05225
926570011470	Domain of unknown function DUF29; Region: DUF29; pfam01724
926570011471	MobA/MobL family; Region: MobA_MobL; pfam03389