-- dump date   	20140618_185225
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1198114000001	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1198114000002	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1198114000003	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1198114000004	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1198114000005	Clp amino terminal domain; Region: Clp_N; pfam02861
1198114000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114000007	Walker A motif; other site
1198114000008	ATP binding site [chemical binding]; other site
1198114000009	Walker B motif; other site
1198114000010	arginine finger; other site
1198114000011	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114000012	Walker A motif; other site
1198114000013	ATP binding site [chemical binding]; other site
1198114000014	Walker B motif; other site
1198114000015	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1198114000016	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1198114000017	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1198114000018	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1198114000019	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1198114000020	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
1198114000021	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1198114000022	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1198114000023	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
1198114000024	ImpE protein; Region: ImpE; pfam07024
1198114000025	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1198114000026	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1198114000027	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1198114000028	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1198114000029	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1198114000030	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1198114000031	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114000032	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114000033	Amidohydrolase; Region: Amidohydro_4; pfam13147
1198114000034	active site
1198114000035	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1198114000036	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1198114000037	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1198114000038	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
1198114000039	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1198114000040	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1198114000041	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1198114000042	active site
1198114000043	Protein phosphatase 2C; Region: PP2C; pfam00481
1198114000044	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1198114000045	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1198114000046	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1198114000047	active site
1198114000048	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1198114000049	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1198114000050	DNA-binding site [nucleotide binding]; DNA binding site
1198114000051	FCD domain; Region: FCD; pfam07729
1198114000052	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1198114000053	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1198114000054	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114000055	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114000056	metal binding site [ion binding]; metal-binding site
1198114000057	active site
1198114000058	I-site; other site
1198114000059	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114000060	magnesium chelatase ATPase subunit I; Region: BchI-ChlI; TIGR02030
1198114000061	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1198114000062	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1198114000063	metal ion-dependent adhesion site (MIDAS); other site
1198114000064	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1198114000065	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989
1198114000066	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
1198114000067	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
1198114000068	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
1198114000069	Probable cobalt transporter subunit (CbtA); Region: CbtA; pfam09490
1198114000070	Probable cobalt transporter subunit (CbtB); Region: CbtB; cl09723
1198114000071	Histidine phosphatase superfamily (branch 1); Region: His_Phos_1; pfam00300
1198114000072	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
1198114000073	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000074	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000075	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1198114000076	Alginate lyase; Region: Alginate_lyase; pfam05426
1198114000077	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1198114000078	Cupin domain; Region: Cupin_2; pfam07883
1198114000079	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1198114000080	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1198114000081	DNA interaction; other site
1198114000082	Metal-binding active site; metal-binding site
1198114000083	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114000084	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114000085	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
1198114000086	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1198114000087	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
1198114000088	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000089	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1198114000090	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114000091	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1198114000092	metal binding site 2 [ion binding]; metal-binding site
1198114000093	putative DNA binding helix; other site
1198114000094	metal binding site 1 [ion binding]; metal-binding site
1198114000095	dimer interface [polypeptide binding]; other site
1198114000096	structural Zn2+ binding site [ion binding]; other site
1198114000097	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1198114000098	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
1198114000099	dimer interface [polypeptide binding]; other site
1198114000100	active site
1198114000101	heme binding site [chemical binding]; other site
1198114000102	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1198114000103	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114000104	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1198114000105	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1198114000106	active site
1198114000107	TDP-binding site; other site
1198114000108	acceptor substrate-binding pocket; other site
1198114000109	homodimer interface [polypeptide binding]; other site
1198114000110	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1198114000111	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114000112	FtsX-like permease family; Region: FtsX; pfam02687
1198114000113	thioester reductase domain; Region: Thioester-redct; TIGR01746
1198114000114	Pseudomonas fluorescens MupV-like, extended (e) SDRs; Region: MupV_like_SDR_e; cd05263
1198114000115	putative NAD(P) binding site [chemical binding]; other site
1198114000116	active site
1198114000117	putative substrate binding site [chemical binding]; other site
1198114000118	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1198114000119	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1198114000120	acyl-activating enzyme (AAE) consensus motif; other site
1198114000121	AMP binding site [chemical binding]; other site
1198114000122	active site
1198114000123	CoA binding site [chemical binding]; other site
1198114000124	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114000125	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114000126	Walker A/P-loop; other site
1198114000127	ATP binding site [chemical binding]; other site
1198114000128	Q-loop/lid; other site
1198114000129	ABC transporter signature motif; other site
1198114000130	Walker B; other site
1198114000131	D-loop; other site
1198114000132	H-loop/switch region; other site
1198114000133	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
1198114000134	active site
1198114000135	catalytic residues [active]
1198114000136	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
1198114000137	metal binding site [ion binding]; metal-binding site
1198114000138	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
1198114000139	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114000140	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1198114000141	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114000142	Transposase; Region: HTH_Tnp_1; pfam01527
1198114000143	CEO family (DUF1632); Region: DUF1632; pfam07857
1198114000144	Family of unknown function (DUF706); Region: DUF706; pfam05153
1198114000145	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1198114000146	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
1198114000147	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1198114000148	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1198114000149	DNA binding site [nucleotide binding]
1198114000150	domain linker motif; other site
1198114000151	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1198114000152	ligand binding site [chemical binding]; other site
1198114000153	dimerization interface [polypeptide binding]; other site
1198114000154	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000155	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
1198114000156	Catalytic domain of Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1-like proteins; Region: PI-PLCc_SaPLC1_like; cd08589
1198114000157	putative active site [active]
1198114000158	catalytic site [active]
1198114000159	putative metal binding site [ion binding]; other site
1198114000160	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1198114000161	Transposase; Region: HTH_Tnp_1; cl17663
1198114000162	N-terminal catalytic domain of rhamnogalacturonan lyase, a family 4 polysaccharide lyase; Region: RGL4_N; cd10320
1198114000163	active site
1198114000164	catalytic site [active]
1198114000165	Middle domain of rhamnogalacturonan lyase, a family 4 polysaccharide lyase; Region: RGL4_M; cd10316
1198114000166	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000167	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1198114000168	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1198114000169	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1198114000170	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1198114000171	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114000172	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114000173	DNA binding site [nucleotide binding]
1198114000174	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000175	binding surface
1198114000176	TPR repeat; Region: TPR_11; pfam13414
1198114000177	TPR motif; other site
1198114000178	TPR repeat; Region: TPR_11; pfam13414
1198114000179	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000180	binding surface
1198114000181	TPR motif; other site
1198114000182	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1198114000183	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
1198114000184	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1198114000185	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
1198114000186	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
1198114000187	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1198114000188	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
1198114000189	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1198114000190	Putative amidoligase enzyme (DUF2126); Region: DUF2126; pfam09899
1198114000191	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4196
1198114000192	PAS domain S-box; Region: sensory_box; TIGR00229
1198114000193	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114000194	putative active site [active]
1198114000195	heme pocket [chemical binding]; other site
1198114000196	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114000197	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114000198	metal binding site [ion binding]; metal-binding site
1198114000199	active site
1198114000200	I-site; other site
1198114000201	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000202	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114000203	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114000204	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
1198114000205	metal binding site [ion binding]; metal-binding site
1198114000206	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000207	binding surface
1198114000208	TPR motif; other site
1198114000209	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1198114000210	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000211	binding surface
1198114000212	TPR motif; other site
1198114000213	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1198114000214	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000215	TPR motif; other site
1198114000216	binding surface
1198114000217	CHAT domain; Region: CHAT; pfam12770
1198114000218	RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; Region: Sig-70_gvs1; TIGR02989
1198114000219	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1198114000220	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
1198114000221	active site
1198114000222	TPR repeat; Region: TPR_11; pfam13414
1198114000223	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000224	binding surface
1198114000225	TPR motif; other site
1198114000226	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114000227	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000228	binding surface
1198114000229	TPR motif; other site
1198114000230	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000231	binding surface
1198114000232	TPR motif; other site
1198114000233	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000234	binding surface
1198114000235	TPR motif; other site
1198114000236	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114000237	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1198114000238	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1198114000239	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1198114000240	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1198114000241	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
1198114000242	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1198114000243	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1198114000244	catalytic loop [active]
1198114000245	iron binding site [ion binding]; other site
1198114000246	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1198114000247	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
1198114000248	Methane oxygenase PmoA; Region: PmoA; pfam14100
1198114000249	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114000250	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114000251	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000252	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114000253	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114000254	active site
1198114000255	phosphorylation site [posttranslational modification]
1198114000256	intermolecular recognition site; other site
1198114000257	dimerization interface [polypeptide binding]; other site
1198114000258	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114000259	DNA binding residues [nucleotide binding]
1198114000260	dimerization interface [polypeptide binding]; other site
1198114000261	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1198114000262	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1198114000263	putative NAD(P) binding site [chemical binding]; other site
1198114000264	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1198114000265	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1198114000266	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114000267	Histidine kinase; Region: HisKA_3; pfam07730
1198114000268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000269	ATP binding site [chemical binding]; other site
1198114000270	Mg2+ binding site [ion binding]; other site
1198114000271	G-X-G motif; other site
1198114000272	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cl00218
1198114000273	active site
1198114000274	catalytic residues [active]
1198114000275	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1198114000276	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1198114000277	Amino acid permease; Region: AA_permease_2; pfam13520
1198114000278	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1198114000279	Na binding site [ion binding]; other site
1198114000280	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1198114000281	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1198114000282	ligand binding site [chemical binding]; other site
1198114000283	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1198114000284	Flagellar protein (FlbD); Region: FlbD; pfam06289
1198114000285	flagellin; Provisional; Region: PRK12804
1198114000286	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1198114000287	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1198114000288	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1198114000289	Flagellar protein FliS; Region: FliS; cl00654
1198114000290	flagellar hook-associated protein 3; Region: flagell_flgL; TIGR02550
1198114000291	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
1198114000292	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1198114000293	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1198114000294	Rod binding protein; Region: Rod-binding; cl01626
1198114000295	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1198114000296	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1198114000297	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1198114000298	Flagellar L-ring protein; Region: FlgH; cl17277
1198114000299	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1198114000300	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1198114000301	flagellar hook-basal body protein; Region: FlgEFG_subfam; TIGR03506
1198114000302	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1198114000303	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1198114000304	Predicted signal transduction protein [Signal transduction mechanisms]; Region: COG1639
1198114000305	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1198114000306	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1198114000307	flagellar motor switch protein FliM; Region: fliM_switch; TIGR01397
1198114000308	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1198114000309	RNA polymerase sigma factor, FliA/WhiG family; Region: FliA_WhiG; TIGR02479
1198114000310	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114000311	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1198114000312	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114000313	DNA binding residues [nucleotide binding]
1198114000314	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1198114000315	FHIPEP family; Region: FHIPEP; pfam00771
1198114000316	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1198114000317	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1198114000318	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1198114000319	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1198114000320	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1198114000321	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
1198114000322	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
1198114000323	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1198114000324	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1198114000325	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1198114000326	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1198114000327	flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496
1198114000328	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1198114000329	Walker A motif/ATP binding site; other site
1198114000330	Walker B motif; other site
1198114000331	Flagellar assembly protein FliH; Region: FliH; pfam02108
1198114000332	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1198114000333	FliG C-terminal domain; Region: FliG_C; pfam01706
1198114000334	Flagellar basal body M-ring protein [Cell motility and secretion]; Region: fliF; COG1766
1198114000335	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1198114000336	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1198114000337	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
1198114000338	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1198114000339	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1198114000340	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1198114000341	Flagellar basal body protein [Cell motility and secretion]; Region: FlgB; COG1815
1198114000342	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1198114000343	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114000344	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114000345	active site
1198114000346	phosphorylation site [posttranslational modification]
1198114000347	intermolecular recognition site; other site
1198114000348	dimerization interface [polypeptide binding]; other site
1198114000349	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114000350	ATP binding site [chemical binding]; other site
1198114000351	Walker A motif; other site
1198114000352	Walker B motif; other site
1198114000353	arginine finger; other site
1198114000354	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114000355	PAS domain; Region: PAS; smart00091
1198114000356	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114000357	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114000358	dimer interface [polypeptide binding]; other site
1198114000359	phosphorylation site [posttranslational modification]
1198114000360	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000361	ATP binding site [chemical binding]; other site
1198114000362	Mg2+ binding site [ion binding]; other site
1198114000363	G-X-G motif; other site
1198114000364	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114000365	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114000366	Walker A motif; other site
1198114000367	ATP binding site [chemical binding]; other site
1198114000368	Walker B motif; other site
1198114000369	arginine finger; other site
1198114000370	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114000371	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114000372	active site
1198114000373	phosphorylation site [posttranslational modification]
1198114000374	intermolecular recognition site; other site
1198114000375	dimerization interface [polypeptide binding]; other site
1198114000376	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114000377	DNA binding site [nucleotide binding]
1198114000378	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1198114000379	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1198114000380	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1198114000381	ligand binding site [chemical binding]; other site
1198114000382	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1198114000383	flagellar motor stator protein MotA; Region: MotA1; TIGR03818
1198114000384	Amidohydrolase; Region: Amidohydro_2; pfam04909
1198114000385	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1198114000386	putative Zn2+ binding site [ion binding]; other site
1198114000387	putative DNA binding site [nucleotide binding]; other site
1198114000388	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1198114000389	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1198114000390	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1198114000391	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000392	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1198114000393	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
1198114000394	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1198114000395	substrate binding site [chemical binding]; other site
1198114000396	activation loop (A-loop); other site
1198114000397	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1198114000398	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1198114000399	metal ion-dependent adhesion site (MIDAS); other site
1198114000400	Uncharacterized conserved protein [Function unknown]; Region: COG5316
1198114000401	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
1198114000402	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1198114000403	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1198114000404	Putative zinc-finger; Region: zf-HC2; pfam13490
1198114000405	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114000406	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114000407	active site
1198114000408	catalytic tetrad [active]
1198114000409	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
1198114000410	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
1198114000411	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1198114000412	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114000413	Amidase; Region: Amidase; cl11426
1198114000414	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000415	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114000416	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114000417	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114000418	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114000419	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1198114000420	Protein export membrane protein; Region: SecD_SecF; cl14618
1198114000421	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1198114000422	Protein export membrane protein; Region: SecD_SecF; cl14618
1198114000423	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1198114000424	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1198114000425	Purine nucleoside permease (NUP); Region: NUP; pfam06516
1198114000426	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1198114000427	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1198114000428	Cl- selectivity filter; other site
1198114000429	Cl- binding residues [ion binding]; other site
1198114000430	pore gating glutamate residue; other site
1198114000431	dimer interface [polypeptide binding]; other site
1198114000432	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000433	binding surface
1198114000434	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114000435	TPR motif; other site
1198114000436	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000437	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
1198114000438	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1198114000439	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1198114000440	ParA-like protein; Provisional; Region: PHA02518
1198114000441	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1198114000442	P-loop; other site
1198114000443	Magnesium ion binding site [ion binding]; other site
1198114000444	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1198114000445	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114000446	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000447	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1198114000448	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114000449	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114000450	peptidase domain interface [polypeptide binding]; other site
1198114000451	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114000452	active site
1198114000453	catalytic triad [active]
1198114000454	calcium binding site [ion binding]; other site
1198114000455	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1198114000456	dimer interface [polypeptide binding]; other site
1198114000457	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114000458	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1198114000459	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114000460	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1198114000461	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1198114000462	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
1198114000463	Glycosyl hydrolase family 43, includes mostly 1,4-beta-xylanases; Region: GH43_bXyl; cd09004
1198114000464	putative substrate binding site [chemical binding]; other site
1198114000465	active site
1198114000466	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1198114000467	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1198114000468	Potassium binding sites [ion binding]; other site
1198114000469	Cesium cation binding sites [ion binding]; other site
1198114000470	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1198114000471	beta-galactosidase; Region: BGL; TIGR03356
1198114000472	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000473	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114000474	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1198114000475	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1198114000476	DNA-binding site [nucleotide binding]; DNA binding site
1198114000477	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1198114000478	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1198114000479	ligand binding site [chemical binding]; other site
1198114000480	dimerization interface [polypeptide binding]; other site
1198114000481	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1198114000482	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000483	putative substrate translocation pore; other site
1198114000484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000485	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1198114000486	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1198114000487	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1198114000488	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
1198114000489	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1198114000490	Family description; Region: VCBS; pfam13517
1198114000491	Family description; Region: VCBS; pfam13517
1198114000492	Family description; Region: VCBS; pfam13517
1198114000493	Family description; Region: VCBS; pfam13517
1198114000494	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1198114000495	Family description; Region: VCBS; pfam13517
1198114000496	DNA binding site [nucleotide binding]
1198114000497	clamp; other site
1198114000498	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1198114000499	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
1198114000500	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000501	binding surface
1198114000502	TPR motif; other site
1198114000503	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1198114000504	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000505	binding surface
1198114000506	TPR motif; other site
1198114000507	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114000508	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114000509	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1198114000510	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1198114000511	Family description; Region: VCBS; pfam13517
1198114000512	Family description; Region: VCBS; pfam13517
1198114000513	Family description; Region: VCBS; pfam13517
1198114000514	Family description; Region: VCBS; pfam13517
1198114000515	Family description; Region: VCBS; pfam13517
1198114000516	Family description; Region: VCBS; pfam13517
1198114000517	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1198114000518	Family description; Region: VCBS; pfam13517
1198114000519	Family description; Region: VCBS; pfam13517
1198114000520	Family description; Region: VCBS; pfam13517
1198114000521	Family description; Region: VCBS; pfam13517
1198114000522	Family description; Region: VCBS; pfam13517
1198114000523	Family description; Region: VCBS; pfam13517
1198114000524	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1198114000525	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114000526	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000527	TPR motif; other site
1198114000528	binding surface
1198114000529	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000530	TPR motif; other site
1198114000531	binding surface
1198114000532	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1198114000533	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1198114000534	Ca binding site [ion binding]; other site
1198114000535	active site
1198114000536	catalytic site [active]
1198114000537	Trehalase; Region: Trehalase; cl17346
1198114000538	Putative Tad-like Flp pilus-assembly; Region: Tad_C; pfam09977
1198114000539	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114000540	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114000541	DNA binding site [nucleotide binding]
1198114000542	TPR repeat; Region: TPR_11; pfam13414
1198114000543	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000544	TPR motif; other site
1198114000545	binding surface
1198114000546	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000547	TPR motif; other site
1198114000548	binding surface
1198114000549	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1198114000550	Gloeo_Verruco repeat; Region: Gloeo_Verruco; TIGR03803
1198114000551	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114000552	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1198114000553	active site
1198114000554	catalytic residues [active]
1198114000555	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1198114000556	catalytic residues [active]
1198114000557	Protein of unknown function (DUF419); Region: DUF419; pfam04237
1198114000558	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159
1198114000559	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000560	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1198114000561	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495
1198114000562	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114000563	metal binding site [ion binding]; metal-binding site
1198114000564	active site
1198114000565	I-site; other site
1198114000566	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114000567	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1198114000568	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1198114000569	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114000570	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
1198114000571	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000572	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
1198114000573	Peptidase family M1; Region: Peptidase_M1; pfam01433
1198114000574	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1198114000575	Zn binding site [ion binding]; other site
1198114000576	HEAT repeats; Region: HEAT_2; pfam13646
1198114000577	hypothetical protein; Provisional; Region: PRK06489
1198114000578	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1198114000579	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1198114000580	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1198114000581	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1198114000582	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1198114000583	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
1198114000584	dimer interface [polypeptide binding]; other site
1198114000585	NADP binding site [chemical binding]; other site
1198114000586	catalytic residues [active]
1198114000587	hydroxyproline-2-epimerase; Provisional; Region: PRK13970
1198114000588	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
1198114000589	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1198114000590	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1198114000591	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510
1198114000592	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1198114000593	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1198114000594	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1198114000595	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1198114000596	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1198114000597	inhibitor site; inhibition site
1198114000598	active site
1198114000599	dimer interface [polypeptide binding]; other site
1198114000600	catalytic residue [active]
1198114000601	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1198114000602	Zn binding site [ion binding]; other site
1198114000603	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1198114000604	active site
1198114000605	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
1198114000606	proline aminopeptidase P II; Provisional; Region: PRK10879
1198114000607	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1198114000608	active site
1198114000609	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1198114000610	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1198114000611	DNA-binding site [nucleotide binding]; DNA binding site
1198114000612	FCD domain; Region: FCD; pfam07729
1198114000613	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000614	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
1198114000615	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1198114000616	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
1198114000617	active site
1198114000618	catalytic site [active]
1198114000619	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1198114000620	IHF dimer interface [polypeptide binding]; other site
1198114000621	IHF - DNA interface [nucleotide binding]; other site
1198114000622	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000623	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114000624	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114000625	benzoate transport; Region: 2A0115; TIGR00895
1198114000626	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000627	putative substrate translocation pore; other site
1198114000628	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114000629	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114000630	DNA binding site [nucleotide binding]
1198114000631	Predicted integral membrane protein [Function unknown]; Region: COG5616
1198114000632	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000633	TPR repeat; Region: TPR_11; pfam13414
1198114000634	binding surface
1198114000635	TPR motif; other site
1198114000636	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000637	TPR motif; other site
1198114000638	binding surface
1198114000639	TPR repeat; Region: TPR_11; pfam13414
1198114000640	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114000641	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114000642	FecR protein; Region: FecR; pfam04773
1198114000643	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1198114000644	IHF dimer interface [polypeptide binding]; other site
1198114000645	IHF - DNA interface [nucleotide binding]; other site
1198114000646	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1198114000647	active site
1198114000648	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
1198114000649	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1198114000650	Uncharacterized conserved protein [Function unknown]; Region: COG5649
1198114000651	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1198114000652	oligomeric interface; other site
1198114000653	putative active site [active]
1198114000654	homodimer interface [polypeptide binding]; other site
1198114000655	Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408
1198114000656	Protein of unknown function (DUF1355); Region: DUF1355; cl17712
1198114000657	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000658	TPR motif; other site
1198114000659	TPR repeat; Region: TPR_11; pfam13414
1198114000660	binding surface
1198114000661	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000662	TPR motif; other site
1198114000663	binding surface
1198114000664	TPR repeat; Region: TPR_11; pfam13414
1198114000665	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000666	TPR motif; other site
1198114000667	binding surface
1198114000668	TPR repeat; Region: TPR_11; pfam13414
1198114000669	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000670	TPR motif; other site
1198114000671	binding surface
1198114000672	TPR repeat; Region: TPR_11; pfam13414
1198114000673	decaheme c-type cytochrome, DmsE family; Region: decahem_SO; TIGR03508
1198114000674	Doubled CXXCH motif (Paired_CXXCH_1); Region: Paired_CXXCH_1; cl09905
1198114000675	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114000676	binding surface
1198114000677	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114000678	TPR motif; other site
1198114000679	GAF domain; Region: GAF_2; pfam13185
1198114000680	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114000681	metal binding site [ion binding]; metal-binding site
1198114000682	active site
1198114000683	I-site; other site
1198114000684	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114000685	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1198114000686	dimer interface [polypeptide binding]; other site
1198114000687	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114000688	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114000689	active site
1198114000690	phosphorylation site [posttranslational modification]
1198114000691	intermolecular recognition site; other site
1198114000692	dimerization interface [polypeptide binding]; other site
1198114000693	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114000694	DNA binding site [nucleotide binding]
1198114000695	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114000696	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1198114000697	dimerization interface [polypeptide binding]; other site
1198114000698	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114000699	dimer interface [polypeptide binding]; other site
1198114000700	phosphorylation site [posttranslational modification]
1198114000701	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000702	ATP binding site [chemical binding]; other site
1198114000703	Mg2+ binding site [ion binding]; other site
1198114000704	G-X-G motif; other site
1198114000705	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000706	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1198114000707	putative substrate translocation pore; other site
1198114000708	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000709	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1198114000710	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1198114000711	active site
1198114000712	ATP binding site [chemical binding]; other site
1198114000713	substrate binding site [chemical binding]; other site
1198114000714	activation loop (A-loop); other site
1198114000715	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1198114000716	Domain of unknown function (DUF4267); Region: DUF4267; pfam14087
1198114000717	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114000718	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114000719	WHG domain; Region: WHG; pfam13305
1198114000720	alpha-galactosidase; Region: PLN02808; cl17638
1198114000721	Transposase; Region: HTH_Tnp_1; pfam01527
1198114000722	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
1198114000723	HTH-like domain; Region: HTH_21; pfam13276
1198114000724	Integrase core domain; Region: rve; pfam00665
1198114000725	Integrase core domain; Region: rve_3; pfam13683
1198114000726	GAF domain; Region: GAF; pfam01590
1198114000727	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114000728	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114000729	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114000730	putative active site [active]
1198114000731	heme pocket [chemical binding]; other site
1198114000732	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114000733	dimer interface [polypeptide binding]; other site
1198114000734	phosphorylation site [posttranslational modification]
1198114000735	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000736	ATP binding site [chemical binding]; other site
1198114000737	Mg2+ binding site [ion binding]; other site
1198114000738	G-X-G motif; other site
1198114000739	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
1198114000740	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1198114000741	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1198114000742	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1198114000743	Zn binding site [ion binding]; other site
1198114000744	Pseudomonas putida aldehyde-dismutating formaldehyde dehydrogenase (PFDH); Region: PFDH_like; cd08282
1198114000745	formaldehyde dehydrogenase, glutathione-independent; Region: fdhA_non_GSH; TIGR02819
1198114000746	NAD binding site [chemical binding]; other site
1198114000747	catalytic Zn binding site [ion binding]; other site
1198114000748	structural Zn binding site [ion binding]; other site
1198114000749	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114000750	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1198114000751	TAP-like protein; Region: Abhydrolase_4; pfam08386
1198114000752	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114000753	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
1198114000754	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1198114000755	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 3. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_3; cd03328
1198114000756	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1198114000757	putative active site pocket [active]
1198114000758	putative metal binding site [ion binding]; other site
1198114000759	thiamine pyrophosphate protein; Provisional; Region: PRK08273
1198114000760	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1198114000761	PYR/PP interface [polypeptide binding]; other site
1198114000762	tetramer interface [polypeptide binding]; other site
1198114000763	dimer interface [polypeptide binding]; other site
1198114000764	TPP binding site [chemical binding]; other site
1198114000765	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1198114000766	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1198114000767	TPP-binding site [chemical binding]; other site
1198114000768	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1198114000769	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1198114000770	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114000771	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114000772	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000773	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1198114000774	putative substrate translocation pore; other site
1198114000775	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000776	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000777	benzoate transport; Region: 2A0115; TIGR00895
1198114000778	putative substrate translocation pore; other site
1198114000779	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114000780	Predicted membrane protein [Function unknown]; Region: COG2323
1198114000781	Predicted membrane protein [Function unknown]; Region: COG2323
1198114000782	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1198114000783	dinuclear metal binding motif [ion binding]; other site
1198114000784	Ferritin-like domain; Region: Ferritin_2; pfam13668
1198114000785	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971
1198114000786	DNA binding site [nucleotide binding]
1198114000787	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
1198114000788	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114000789	FeS/SAM binding site; other site
1198114000790	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114000791	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114000792	active site
1198114000793	phosphorylation site [posttranslational modification]
1198114000794	intermolecular recognition site; other site
1198114000795	dimerization interface [polypeptide binding]; other site
1198114000796	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114000797	DNA-binding site [nucleotide binding]; DNA binding site
1198114000798	RNA-binding motif; other site
1198114000799	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114000800	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1198114000801	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1198114000802	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114000803	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114000804	dimer interface [polypeptide binding]; other site
1198114000805	phosphorylation site [posttranslational modification]
1198114000806	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000807	ATP binding site [chemical binding]; other site
1198114000808	Mg2+ binding site [ion binding]; other site
1198114000809	G-X-G motif; other site
1198114000810	GAF domain; Region: GAF; pfam01590
1198114000811	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114000812	PAS domain S-box; Region: sensory_box; TIGR00229
1198114000813	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114000814	putative active site [active]
1198114000815	heme pocket [chemical binding]; other site
1198114000816	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114000817	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114000818	dimer interface [polypeptide binding]; other site
1198114000819	phosphorylation site [posttranslational modification]
1198114000820	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000821	ATP binding site [chemical binding]; other site
1198114000822	Mg2+ binding site [ion binding]; other site
1198114000823	G-X-G motif; other site
1198114000824	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114000825	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114000826	ligand binding site [chemical binding]; other site
1198114000827	flexible hinge region; other site
1198114000828	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1198114000829	putative switch regulator; other site
1198114000830	non-specific DNA interactions [nucleotide binding]; other site
1198114000831	DNA binding site [nucleotide binding]
1198114000832	sequence specific DNA binding site [nucleotide binding]; other site
1198114000833	putative cAMP binding site [chemical binding]; other site
1198114000834	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114000835	KH domain; Region: KH_4; pfam13083
1198114000836	G-X-X-G motif; other site
1198114000837	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1198114000838	active site
1198114000839	phosphorylation site [posttranslational modification]
1198114000840	intermolecular recognition site; other site
1198114000841	dimerization interface [polypeptide binding]; other site
1198114000842	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1198114000843	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114000844	phosphorylation site [posttranslational modification]
1198114000845	dimer interface [polypeptide binding]; other site
1198114000846	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000847	ATP binding site [chemical binding]; other site
1198114000848	Mg2+ binding site [ion binding]; other site
1198114000849	G-X-G motif; other site
1198114000850	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114000851	DNA-binding site [nucleotide binding]; DNA binding site
1198114000852	RNA-binding motif; other site
1198114000853	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114000854	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1198114000855	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1198114000856	putative switch regulator; other site
1198114000857	non-specific DNA interactions [nucleotide binding]; other site
1198114000858	DNA binding site [nucleotide binding]
1198114000859	sequence specific DNA binding site [nucleotide binding]; other site
1198114000860	putative cAMP binding site [chemical binding]; other site
1198114000861	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114000862	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114000863	active site
1198114000864	phosphorylation site [posttranslational modification]
1198114000865	intermolecular recognition site; other site
1198114000866	dimerization interface [polypeptide binding]; other site
1198114000867	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1198114000868	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114000869	catalytic residues [active]
1198114000870	catalytic nucleophile [active]
1198114000871	Presynaptic Site I dimer interface [polypeptide binding]; other site
1198114000872	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1198114000873	Synaptic Flat tetramer interface [polypeptide binding]; other site
1198114000874	Synaptic Site I dimer interface [polypeptide binding]; other site
1198114000875	DNA binding site [nucleotide binding]
1198114000876	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1198114000877	DNA-binding interface [nucleotide binding]; DNA binding site
1198114000878	Epoxide hydrolase N terminus; Region: EHN; pfam06441
1198114000879	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114000880	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1198114000881	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1198114000882	catalytic residues [active]
1198114000883	catalytic nucleophile [active]
1198114000884	Presynaptic Site I dimer interface [polypeptide binding]; other site
1198114000885	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1198114000886	Synaptic Flat tetramer interface [polypeptide binding]; other site
1198114000887	Synaptic Site I dimer interface [polypeptide binding]; other site
1198114000888	DNA binding site [nucleotide binding]
1198114000889	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1198114000890	DNA-binding interface [nucleotide binding]; DNA binding site
1198114000891	Winged helix-turn helix; Region: HTH_29; pfam13551
1198114000892	Homeodomain-like domain; Region: HTH_23; pfam13384
1198114000893	Homeodomain-like domain; Region: HTH_32; pfam13565
1198114000894	Integrase core domain; Region: rve; pfam00665
1198114000895	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
1198114000896	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
1198114000897	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1198114000898	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114000899	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114000900	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114000901	PAS domain; Region: PAS_9; pfam13426
1198114000902	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114000903	PAS fold; Region: PAS_3; pfam08447
1198114000904	putative active site [active]
1198114000905	heme pocket [chemical binding]; other site
1198114000906	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114000907	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cd02409
1198114000908	G-X-X-G motif; other site
1198114000909	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1198114000910	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1198114000911	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1198114000912	ligand binding site [chemical binding]; other site
1198114000913	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114000914	PAS fold; Region: PAS_4; pfam08448
1198114000915	PAS domain S-box; Region: sensory_box; TIGR00229
1198114000916	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114000917	putative active site [active]
1198114000918	heme pocket [chemical binding]; other site
1198114000919	Y-family of DNA polymerases; Region: PolY; cl12025
1198114000920	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1198114000921	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1198114000922	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114000923	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
1198114000924	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
1198114000925	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1198114000926	nucleoside/Zn binding site; other site
1198114000927	dimer interface [polypeptide binding]; other site
1198114000928	catalytic motif [active]
1198114000929	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1198114000930	dimerization interface [polypeptide binding]; other site
1198114000931	metal binding site [ion binding]; metal-binding site
1198114000932	error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672
1198114000933	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1198114000934	active site
1198114000935	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1198114000936	generic binding surface II; other site
1198114000937	generic binding surface I; other site
1198114000938	DNA Polymerase Y-family; Region: PolY_like; cd03468
1198114000939	active site
1198114000940	DNA binding site [nucleotide binding]
1198114000941	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114000942	Walker A motif; other site
1198114000943	ATP binding site [chemical binding]; other site
1198114000944	Protein of unknown function (DUF1810); Region: DUF1810; pfam08837
1198114000945	Protein of unknown function (DUF1003); Region: DUF1003; cl01831
1198114000946	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
1198114000947	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1198114000948	dimerization interface [polypeptide binding]; other site
1198114000949	putative DNA binding site [nucleotide binding]; other site
1198114000950	putative Zn2+ binding site [ion binding]; other site
1198114000951	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1198114000952	dinuclear metal binding motif [ion binding]; other site
1198114000953	VIT family; Region: VIT1; pfam01988
1198114000954	hypothetical protein; Provisional; Region: PRK06132
1198114000955	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1198114000956	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1198114000957	PAS domain; Region: PAS_9; pfam13426
1198114000958	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114000959	putative active site [active]
1198114000960	heme pocket [chemical binding]; other site
1198114000961	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114000962	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114000963	dimer interface [polypeptide binding]; other site
1198114000964	phosphorylation site [posttranslational modification]
1198114000965	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114000966	ATP binding site [chemical binding]; other site
1198114000967	Mg2+ binding site [ion binding]; other site
1198114000968	G-X-G motif; other site
1198114000969	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114000970	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114000971	ligand binding site [chemical binding]; other site
1198114000972	flexible hinge region; other site
1198114000973	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1198114000974	putative switch regulator; other site
1198114000975	non-specific DNA interactions [nucleotide binding]; other site
1198114000976	DNA binding site [nucleotide binding]
1198114000977	sequence specific DNA binding site [nucleotide binding]; other site
1198114000978	putative cAMP binding site [chemical binding]; other site
1198114000979	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1198114000980	Nitroreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_2; cd02138
1198114000981	putative FMN binding site [chemical binding]; other site
1198114000982	bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404
1198114000983	Cupin; Region: Cupin_1; smart00835
1198114000984	Cupin; Region: Cupin_1; smart00835
1198114000985	Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Region: PulA; COG1523
1198114000986	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1198114000987	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1198114000988	active site
1198114000989	catalytic site [active]
1198114000990	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1198114000991	Ligand Binding Site [chemical binding]; other site
1198114000992	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
1198114000993	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1198114000994	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114000995	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1198114000996	Thioredoxin; Region: Thioredoxin_4; cl17273
1198114000997	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1198114000998	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD2; cd08298
1198114000999	putative NAD(P) binding site [chemical binding]; other site
1198114001000	putative substrate binding site [chemical binding]; other site
1198114001001	catalytic Zn binding site [ion binding]; other site
1198114001002	structural Zn binding site [ion binding]; other site
1198114001003	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1198114001004	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1198114001005	NAD(P) binding site [chemical binding]; other site
1198114001006	catalytic residues [active]
1198114001007	Protein of unknown function (DUF3478); Region: DUF3478; pfam11964
1198114001008	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1198114001009	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_11; cd12175
1198114001010	putative ligand binding site [chemical binding]; other site
1198114001011	putative NAD binding site [chemical binding]; other site
1198114001012	catalytic site [active]
1198114001013	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
1198114001014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114001015	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
1198114001016	putative substrate translocation pore; other site
1198114001017	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
1198114001018	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1198114001019	dimer interface [polypeptide binding]; other site
1198114001020	PYR/PP interface [polypeptide binding]; other site
1198114001021	TPP binding site [chemical binding]; other site
1198114001022	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1198114001023	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1198114001024	TPP-binding site [chemical binding]; other site
1198114001025	dimer interface [polypeptide binding]; other site
1198114001026	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1198114001027	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1198114001028	dimer interface [polypeptide binding]; other site
1198114001029	ssDNA binding site [nucleotide binding]; other site
1198114001030	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1198114001031	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1198114001032	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1198114001033	ParA-like protein; Provisional; Region: PHA02518
1198114001034	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1198114001035	P-loop; other site
1198114001036	Magnesium ion binding site [ion binding]; other site
1198114001037	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
1198114001038	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1198114001039	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114001040	non-specific DNA binding site [nucleotide binding]; other site
1198114001041	salt bridge; other site
1198114001042	sequence-specific DNA binding site [nucleotide binding]; other site
1198114001043	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
1198114001044	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1198114001045	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1198114001046	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
1198114001047	VirB7 interaction site; other site
1198114001048	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1198114001049	VirB8 protein; Region: VirB8; cl01500
1198114001050	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
1198114001051	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114001052	Walker A motif; other site
1198114001053	ATP binding site [chemical binding]; other site
1198114001054	Walker B motif; other site
1198114001055	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
1198114001056	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114001057	Walker A motif; other site
1198114001058	ATP binding site [chemical binding]; other site
1198114001059	Walker B motif; other site
1198114001060	TrwC relaxase; Region: TrwC; pfam08751
1198114001061	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1198114001062	AAA domain; Region: AAA_30; pfam13604
1198114001063	Family description; Region: UvrD_C_2; pfam13538
1198114001064	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114001065	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114001066	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114001067	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1198114001068	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1198114001069	catalytic residues [active]
1198114001070	catalytic nucleophile [active]
1198114001071	Presynaptic Site I dimer interface [polypeptide binding]; other site
1198114001072	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1198114001073	Synaptic Flat tetramer interface [polypeptide binding]; other site
1198114001074	Synaptic Site I dimer interface [polypeptide binding]; other site
1198114001075	DNA binding site [nucleotide binding]
1198114001076	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1198114001077	DNA-binding interface [nucleotide binding]; DNA binding site
1198114001078	Cytochrome oxidase complex assembly protein 1; Region: Coa1; pfam08695
1198114001079	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1198114001080	Putative esterase; Region: Esterase; pfam00756
1198114001081	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114001082	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114001083	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114001084	Barstar (barnase inhibitor); Region: Barstar; pfam01337
1198114001085	RNAase interaction site [polypeptide binding]; other site
1198114001086	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1198114001087	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114001088	active site
1198114001089	phosphorylation site [posttranslational modification]
1198114001090	intermolecular recognition site; other site
1198114001091	dimerization interface [polypeptide binding]; other site
1198114001092	LytTr DNA-binding domain; Region: LytTR; smart00850
1198114001093	Histidine kinase; Region: His_kinase; pfam06580
1198114001094	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114001095	ATP binding site [chemical binding]; other site
1198114001096	Mg2+ binding site [ion binding]; other site
1198114001097	G-X-G motif; other site
1198114001098	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1198114001099	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1198114001100	active site
1198114001101	Zn binding site [ion binding]; other site
1198114001102	Retinal pigment epithelial membrane protein; Region: RPE65; cl10080
1198114001103	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1198114001104	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114001105	active site
1198114001106	phosphorylation site [posttranslational modification]
1198114001107	intermolecular recognition site; other site
1198114001108	dimerization interface [polypeptide binding]; other site
1198114001109	LytTr DNA-binding domain; Region: LytTR; smart00850
1198114001110	Histidine kinase; Region: His_kinase; pfam06580
1198114001111	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114001112	ATP binding site [chemical binding]; other site
1198114001113	Mg2+ binding site [ion binding]; other site
1198114001114	G-X-G motif; other site
1198114001115	Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504
1198114001116	SnoaL-like domain; Region: SnoaL_3; pfam13474
1198114001117	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
1198114001118	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1198114001119	Beta-lactamase; Region: Beta-lactamase; pfam00144
1198114001120	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1198114001121	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114001122	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
1198114001123	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4705
1198114001124	Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988
1198114001125	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
1198114001126	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1198114001127	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114001128	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114001129	DinB superfamily; Region: DinB_2; pfam12867
1198114001130	DinB family; Region: DinB; cl17821
1198114001131	Helix-turn-helix domain; Region: HTH_28; pfam13518
1198114001132	Winged helix-turn helix; Region: HTH_29; pfam13551
1198114001133	Homeodomain-like domain; Region: HTH_32; pfam13565
1198114001134	Integrase core domain; Region: rve; pfam00665
1198114001135	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1198114001136	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114001137	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114001138	KH domain; Region: KH_4; pfam13083
1198114001139	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
1198114001140	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
1198114001141	putative active site [active]
1198114001142	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1198114001143	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114001144	NAD(P) binding site [chemical binding]; other site
1198114001145	active site
1198114001146	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1198114001147	FAD binding domain; Region: FAD_binding_4; pfam01565
1198114001148	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
1198114001149	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1198114001150	active site
1198114001151	substrate binding site [chemical binding]; other site
1198114001152	metal binding site [ion binding]; metal-binding site
1198114001153	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1198114001154	putative active site [active]
1198114001155	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1198114001156	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1198114001157	Ligand binding site; other site
1198114001158	metal-binding site
1198114001159	hypothetical protein; Validated; Region: PRK08238
1198114001160	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324
1198114001161	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114001162	non-specific DNA binding site [nucleotide binding]; other site
1198114001163	salt bridge; other site
1198114001164	sequence-specific DNA binding site [nucleotide binding]; other site
1198114001165	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1198114001166	L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434
1198114001167	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1198114001168	HipA N-terminal domain; Region: Couple_hipA; pfam13657
1198114001169	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1198114001170	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1198114001171	TrwC relaxase; Region: TrwC; pfam08751
1198114001172	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1198114001173	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1198114001174	AAA domain; Region: AAA_30; pfam13604
1198114001175	AAA domain; Region: AAA_22; pfam13401
1198114001176	Family description; Region: UvrD_C_2; pfam13538
1198114001177	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
1198114001178	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1198114001179	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114001180	catalytic residues [active]
1198114001181	catalytic nucleophile [active]
1198114001182	Recombinase; Region: Recombinase; pfam07508
1198114001183	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114001184	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114001185	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114001186	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114001187	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114001188	active site
1198114001189	phosphorylation site [posttranslational modification]
1198114001190	intermolecular recognition site; other site
1198114001191	dimerization interface [polypeptide binding]; other site
1198114001192	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114001193	non-specific DNA binding site [nucleotide binding]; other site
1198114001194	sequence-specific DNA binding site [nucleotide binding]; other site
1198114001195	salt bridge; other site
1198114001196	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1198114001197	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1198114001198	oligomeric interface; other site
1198114001199	putative active site [active]
1198114001200	homodimer interface [polypeptide binding]; other site
1198114001201	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
1198114001202	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1198114001203	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1198114001204	P-loop; other site
1198114001205	Magnesium ion binding site [ion binding]; other site
1198114001206	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
1198114001207	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
1198114001208	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1198114001209	putative sugar binding sites [chemical binding]; other site
1198114001210	Q-X-W motif; other site
1198114001211	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114001212	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114001213	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1198114001214	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114001215	active site
1198114001216	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1198114001217	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114001218	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1198114001219	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1198114001220	NADP binding site [chemical binding]; other site
1198114001221	active site
1198114001222	putative substrate binding site [chemical binding]; other site
1198114001223	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1198114001224	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1198114001225	substrate binding site; other site
1198114001226	tetramer interface; other site
1198114001227	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1198114001228	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1198114001229	NAD binding site [chemical binding]; other site
1198114001230	substrate binding site [chemical binding]; other site
1198114001231	homodimer interface [polypeptide binding]; other site
1198114001232	active site
1198114001233	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1198114001234	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1198114001235	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1198114001236	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
1198114001237	putative ligand binding site [chemical binding]; other site
1198114001238	putative catalytic site [active]
1198114001239	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114001240	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114001241	active site
1198114001242	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1198114001243	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114001244	active site
1198114001245	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114001246	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1198114001247	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114001248	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1198114001249	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1198114001250	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1198114001251	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
1198114001252	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114001253	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1198114001254	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
1198114001255	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
1198114001256	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1198114001257	putative sugar binding sites [chemical binding]; other site
1198114001258	Q-X-W motif; other site
1198114001259	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
1198114001260	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1198114001261	putative sugar binding sites [chemical binding]; other site
1198114001262	Q-X-W motif; other site
1198114001263	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1198114001264	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
1198114001265	SLBB domain; Region: SLBB; pfam10531
1198114001266	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1198114001267	polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Region: pepcterm_ChnLen; TIGR03007
1198114001268	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1198114001269	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114001270	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114001271	catalytic residue [active]
1198114001272	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1198114001273	active site
1198114001274	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1198114001275	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1198114001276	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114001277	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
1198114001278	putative ADP-binding pocket [chemical binding]; other site
1198114001279	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1198114001280	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114001281	active site
1198114001282	DNA binding site [nucleotide binding]
1198114001283	Int/Topo IB signature motif; other site
1198114001284	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114001285	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114001286	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114001287	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114001288	Domain of unknown function (DUF2383); Region: DUF2383; cl17556
1198114001289	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1198114001290	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1198114001291	Homeodomain-like domain; Region: HTH_32; pfam13565
1198114001292	Integrase core domain; Region: rve; pfam00665
1198114001293	Glycosyltransferase (GlcNAc); Region: GlcNAc; pfam11397
1198114001294	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
1198114001295	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1198114001296	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1198114001297	FOG: PKD repeat [General function prediction only]; Region: COG3291
1198114001298	Protein of unknown function (DUF2846); Region: DUF2846; pfam11008
1198114001299	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1198114001300	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114001301	catalytic residues [active]
1198114001302	catalytic nucleophile [active]
1198114001303	TrwC relaxase; Region: TrwC; pfam08751
1198114001304	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1198114001305	AAA domain; Region: AAA_30; pfam13604
1198114001306	Family description; Region: UvrD_C_2; pfam13538
1198114001307	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114001308	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
1198114001309	Walker A motif; other site
1198114001310	ATP binding site [chemical binding]; other site
1198114001311	Walker B motif; other site
1198114001312	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1198114001313	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1198114001314	ATP binding site [chemical binding]; other site
1198114001315	Walker A motif; other site
1198114001316	hexamer interface [polypeptide binding]; other site
1198114001317	Walker B motif; other site
1198114001318	VirB8 protein; Region: VirB8; cl01500
1198114001319	conjugal transfer protein TrbI; Provisional; Region: PRK13881
1198114001320	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1198114001321	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1198114001322	VirB7 interaction site; other site
1198114001323	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1198114001324	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1198114001325	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
1198114001326	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114001327	AAA domain; Region: AAA_22; pfam13401
1198114001328	Walker A motif; other site
1198114001329	ATP binding site [chemical binding]; other site
1198114001330	Walker B motif; other site
1198114001331	arginine finger; other site
1198114001332	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1198114001333	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
1198114001334	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1198114001335	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1198114001336	P-loop; other site
1198114001337	Magnesium ion binding site [ion binding]; other site
1198114001338	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114001339	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1198114001340	active site
1198114001341	DNA binding site [nucleotide binding]
1198114001342	Int/Topo IB signature motif; other site
1198114001343	LabA_like proteins; Region: LabA_like; cd06167
1198114001344	putative metal binding site [ion binding]; other site
1198114001345	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114001346	PAS fold; Region: PAS_4; pfam08448
1198114001347	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114001348	putative active site [active]
1198114001349	heme pocket [chemical binding]; other site
1198114001350	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114001351	PAS fold; Region: PAS_3; pfam08447
1198114001352	putative active site [active]
1198114001353	heme pocket [chemical binding]; other site
1198114001354	PAS domain; Region: PAS_9; pfam13426
1198114001355	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114001356	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1198114001357	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1198114001358	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1198114001359	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1198114001360	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114001361	binding surface
1198114001362	TPR motif; other site
1198114001363	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114001364	AAA domain; Region: AAA_21; pfam13304
1198114001365	Walker A/P-loop; other site
1198114001366	ATP binding site [chemical binding]; other site
1198114001367	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1198114001368	putative active site [active]
1198114001369	putative metal-binding site [ion binding]; other site
1198114001370	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1198114001371	AAA domain; Region: AAA_30; pfam13604
1198114001372	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114001373	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1198114001374	catalytic residues [active]
1198114001375	catalytic nucleophile [active]
1198114001376	Presynaptic Site I dimer interface [polypeptide binding]; other site
1198114001377	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1198114001378	Synaptic Flat tetramer interface [polypeptide binding]; other site
1198114001379	Synaptic Site I dimer interface [polypeptide binding]; other site
1198114001380	DNA binding site [nucleotide binding]
1198114001381	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1198114001382	DNA-binding interface [nucleotide binding]; DNA binding site
1198114001383	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1198114001384	active site
1198114001385	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114001386	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114001387	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114001388	HEAT repeats; Region: HEAT_2; pfam13646
1198114001389	HEAT repeats; Region: HEAT_2; pfam13646
1198114001390	HEAT repeats; Region: HEAT_2; pfam13646
1198114001391	HEAT repeats; Region: HEAT_2; pfam13646
1198114001392	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114001393	active site
1198114001394	DNA binding site [nucleotide binding]
1198114001395	Int/Topo IB signature motif; other site
1198114001396	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1198114001397	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1198114001398	Helix-turn-helix domain; Region: HTH_28; pfam13518
1198114001399	putative transposase OrfB; Reviewed; Region: PHA02517
1198114001400	HTH-like domain; Region: HTH_21; pfam13276
1198114001401	Integrase core domain; Region: rve; pfam00665
1198114001402	Integrase core domain; Region: rve_2; pfam13333
1198114001403	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1198114001404	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1198114001405	catalytic residues [active]
1198114001406	catalytic nucleophile [active]
1198114001407	Presynaptic Site I dimer interface [polypeptide binding]; other site
1198114001408	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1198114001409	Synaptic Flat tetramer interface [polypeptide binding]; other site
1198114001410	Synaptic Site I dimer interface [polypeptide binding]; other site
1198114001411	DNA binding site [nucleotide binding]
1198114001412	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1198114001413	DNA-binding interface [nucleotide binding]; DNA binding site
1198114001414	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114001415	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1198114001416	catalytic residues [active]
1198114001417	catalytic nucleophile [active]
1198114001418	Presynaptic Site I dimer interface [polypeptide binding]; other site
1198114001419	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1198114001420	Synaptic Flat tetramer interface [polypeptide binding]; other site
1198114001421	Synaptic Site I dimer interface [polypeptide binding]; other site
1198114001422	DNA binding site [nucleotide binding]
1198114001423	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1198114001424	DNA-binding interface [nucleotide binding]; DNA binding site
1198114001425	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1198114001426	active site
1198114001427	Domain of unknown function (DUF4279); Region: DUF4279; pfam14106
1198114001428	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1198114001429	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114001430	catalytic residues [active]
1198114001431	catalytic nucleophile [active]
1198114001432	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4306
1198114001433	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1198114001434	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
1198114001435	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114001436	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1198114001437	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114001438	Winged helix-turn helix; Region: HTH_29; pfam13551
1198114001439	Homeodomain-like domain; Region: HTH_32; pfam13565
1198114001440	Integrase core domain; Region: rve; pfam00665
1198114001441	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1198114001442	IHF dimer interface [polypeptide binding]; other site
1198114001443	IHF - DNA interface [nucleotide binding]; other site
1198114001444	Protein of unknown function (DUF3224); Region: DUF3224; pfam11528
1198114001445	SnoaL-like domain; Region: SnoaL_4; pfam13577
1198114001446	SnoaL-like domain; Region: SnoaL_3; pfam13474
1198114001447	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114001448	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1198114001449	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114001450	active site
1198114001451	phosphorylation site [posttranslational modification]
1198114001452	intermolecular recognition site; other site
1198114001453	dimerization interface [polypeptide binding]; other site
1198114001454	LytTr DNA-binding domain; Region: LytTR; smart00850
1198114001455	Histidine kinase; Region: His_kinase; pfam06580
1198114001456	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114001457	ATP binding site [chemical binding]; other site
1198114001458	Mg2+ binding site [ion binding]; other site
1198114001459	G-X-G motif; other site
1198114001460	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1198114001461	Histidine kinase; Region: HisKA_3; pfam07730
1198114001462	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1198114001463	ATP binding site [chemical binding]; other site
1198114001464	Mg2+ binding site [ion binding]; other site
1198114001465	G-X-G motif; other site
1198114001466	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114001467	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114001468	active site
1198114001469	phosphorylation site [posttranslational modification]
1198114001470	intermolecular recognition site; other site
1198114001471	dimerization interface [polypeptide binding]; other site
1198114001472	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114001473	DNA binding residues [nucleotide binding]
1198114001474	dimerization interface [polypeptide binding]; other site
1198114001475	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1198114001476	IHF - DNA interface [nucleotide binding]; other site
1198114001477	IHF dimer interface [polypeptide binding]; other site
1198114001478	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1198114001479	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1198114001480	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114001481	Walker A motif; other site
1198114001482	ATP binding site [chemical binding]; other site
1198114001483	Walker B motif; other site
1198114001484	arginine finger; other site
1198114001485	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1198114001486	DnaA box-binding interface [nucleotide binding]; other site
1198114001487	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1198114001488	DNA polymerase III subunit beta; Validated; Region: PRK05643
1198114001489	putative DNA binding surface [nucleotide binding]; other site
1198114001490	dimer interface [polypeptide binding]; other site
1198114001491	beta-clamp/clamp loader binding surface; other site
1198114001492	beta-clamp/translesion DNA polymerase binding surface; other site
1198114001493	soil-associated protein, TIGR03435 family; Region: Soli_TIGR03435
1198114001494	GAF domain; Region: GAF; pfam01590
1198114001495	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114001496	PAS fold; Region: PAS_3; pfam08447
1198114001497	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1198114001498	putative active site [active]
1198114001499	heme pocket [chemical binding]; other site
1198114001500	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114001501	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114001502	dimer interface [polypeptide binding]; other site
1198114001503	phosphorylation site [posttranslational modification]
1198114001504	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114001505	ATP binding site [chemical binding]; other site
1198114001506	Mg2+ binding site [ion binding]; other site
1198114001507	G-X-G motif; other site
1198114001508	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1198114001509	PLD-like domain; Region: PLDc_2; pfam13091
1198114001510	putative active site [active]
1198114001511	catalytic site [active]
1198114001512	Putative catalytic domain, repeat 2, of uncharacterized phospholipase D-like proteins; Region: PLDc_unchar1_2; cd09128
1198114001513	PLD-like domain; Region: PLDc_2; pfam13091
1198114001514	putative active site [active]
1198114001515	putative catalytic site [active]
1198114001516	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_4; cd07822
1198114001517	putative hydrophobic ligand binding site [chemical binding]; other site
1198114001518	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114001519	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114001520	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114001521	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114001522	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1198114001523	active site
1198114001524	metal binding site [ion binding]; metal-binding site
1198114001525	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1198114001526	MutS domain III; Region: MutS_III; pfam05192
1198114001527	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114001528	Walker A/P-loop; other site
1198114001529	ATP binding site [chemical binding]; other site
1198114001530	Q-loop/lid; other site
1198114001531	ABC transporter signature motif; other site
1198114001532	Walker B; other site
1198114001533	D-loop; other site
1198114001534	H-loop/switch region; other site
1198114001535	Smr domain; Region: Smr; pfam01713
1198114001536	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1198114001537	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1198114001538	active site
1198114001539	Zn binding site [ion binding]; other site
1198114001540	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114001541	NAD(P) binding site [chemical binding]; other site
1198114001542	active site
1198114001543	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1198114001544	dimer interface [polypeptide binding]; other site
1198114001545	active site
1198114001546	Schiff base residues; other site
1198114001547	Protein of unknown function (DUF2614); Region: DUF2614; cl07936
1198114001548	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114001549	putative active site [active]
1198114001550	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1198114001551	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1198114001552	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1198114001553	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1198114001554	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1198114001555	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1198114001556	E3 interaction surface; other site
1198114001557	lipoyl attachment site [posttranslational modification]; other site
1198114001558	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1198114001559	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1198114001560	E3 interaction surface; other site
1198114001561	lipoyl attachment site [posttranslational modification]; other site
1198114001562	e3 binding domain; Region: E3_binding; pfam02817
1198114001563	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1198114001564	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1198114001565	ATP-grasp domain; Region: ATP-grasp; pfam02222
1198114001566	AIR carboxylase; Region: AIRC; pfam00731
1198114001567	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1198114001568	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1198114001569	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1198114001570	dimer interface [polypeptide binding]; other site
1198114001571	active site
1198114001572	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1198114001573	folate binding site [chemical binding]; other site
1198114001574	Predicted membrane protein [Function unknown]; Region: COG3918
1198114001575	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
1198114001576	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114001577	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1198114001578	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1198114001579	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1198114001580	DNA topoisomerase III; Provisional; Region: PRK07726
1198114001581	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1198114001582	active site
1198114001583	putative interdomain interaction site [polypeptide binding]; other site
1198114001584	putative metal-binding site [ion binding]; other site
1198114001585	putative nucleotide binding site [chemical binding]; other site
1198114001586	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1198114001587	domain I; other site
1198114001588	DNA binding groove [nucleotide binding]
1198114001589	phosphate binding site [ion binding]; other site
1198114001590	domain II; other site
1198114001591	domain III; other site
1198114001592	nucleotide binding site [chemical binding]; other site
1198114001593	catalytic site [active]
1198114001594	domain IV; other site
1198114001595	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1198114001596	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1198114001597	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114001598	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114001599	metal binding site [ion binding]; metal-binding site
1198114001600	active site
1198114001601	I-site; other site
1198114001602	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114001603	Cupin domain; Region: Cupin_2; pfam07883
1198114001604	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1198114001605	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1198114001606	active site
1198114001607	catalytic site [active]
1198114001608	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1198114001609	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1198114001610	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1198114001611	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1198114001612	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
1198114001613	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
1198114001614	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1198114001615	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114001616	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1198114001617	FtsX-like permease family; Region: FtsX; pfam02687
1198114001618	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114001619	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1198114001620	FtsX-like permease family; Region: FtsX; pfam02687
1198114001621	hopanoid biosynthesis associated glycosyl transferase protein HpnI; Region: HpnI; TIGR03472
1198114001622	Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520
1198114001623	ligand binding site; other site
1198114001624	Predicted dienelactone hydrolase [General function prediction only]; Region: COG4188
1198114001625	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1198114001626	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1198114001627	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1198114001628	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114001629	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1198114001630	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114001631	DNA binding residues [nucleotide binding]
1198114001632	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1198114001633	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1198114001634	[2Fe-2S] cluster binding site [ion binding]; other site
1198114001635	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1198114001636	hydrophobic ligand binding site; other site
1198114001637	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
1198114001638	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1198114001639	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1198114001640	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1198114001641	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114001642	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114001643	ligand binding site [chemical binding]; other site
1198114001644	flexible hinge region; other site
1198114001645	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
1198114001646	N-terminal putative catalytic domain of mainly uncharacterized prokaryotic proteins similar to archaeal thermoactive amylopullulanases; glycoside hydrolase family 57 (GH57); Region: GH57N_APU_like_1; cd10797
1198114001647	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
1198114001648	active site
1198114001649	catalytic site [active]
1198114001650	Domain of unknown function (DUF3536); Region: DUF3536; pfam12055
1198114001651	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1198114001652	endonuclease III; Region: ENDO3c; smart00478
1198114001653	minor groove reading motif; other site
1198114001654	helix-hairpin-helix signature motif; other site
1198114001655	substrate binding pocket [chemical binding]; other site
1198114001656	active site
1198114001657	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cd08168
1198114001658	heme-binding residues [chemical binding]; other site
1198114001659	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1198114001660	molybdopterin cofactor binding site; other site
1198114001661	The MopB_CT_PHLH CD includes a group of related uncharacterized putative hydrogenase-like homologs (PHLH) of molybdopterin binding proteins. This CD is of the PHLH region homologous to the conserved molybdopterin-binding C-terminal (MopB_CT) region...; Region: MopB_CT_PHLH; cd02784
1198114001662	4Fe-4S binding domain; Region: Fer4; cl02805
1198114001663	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1198114001664	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
1198114001665	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1198114001666	Protein of unknown function (DUF3341); Region: DUF3341; pfam11821
1198114001667	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1198114001668	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1198114001669	Cu(I) binding site [ion binding]; other site
1198114001670	cytochrome c oxidase, subunit II; Region: CoxB; TIGR02866
1198114001671	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1198114001672	Cytochrome c; Region: Cytochrom_C; pfam00034
1198114001673	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1198114001674	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
1198114001675	NorE_like subfamily of heme-copper oxidase subunit III.  Heme-copper oxidases include cytochrome c and ubiquinol oxidases.  Alcaligenes faecalis norE is found in a gene cluster containing norCB. norCB encodes the cytochrome c and cytochrome b subunits of...; Region: NorE_like; cd02862
1198114001676	Subunit I/III interface [polypeptide binding]; other site
1198114001677	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; cl01204
1198114001678	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114001679	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1198114001680	FtsX-like permease family; Region: FtsX; pfam02687
1198114001681	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1198114001682	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1198114001683	active site
1198114001684	catalytic residues [active]
1198114001685	DNA binding site [nucleotide binding]
1198114001686	Int/Topo IB signature motif; other site
1198114001687	Helix-turn-helix domain; Region: HTH_17; pfam12728
1198114001688	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1198114001689	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1198114001690	active site
1198114001691	catalytic residues [active]
1198114001692	DNA binding site [nucleotide binding]
1198114001693	Int/Topo IB signature motif; other site
1198114001694	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114001695	active site
1198114001696	DNA binding site [nucleotide binding]
1198114001697	Int/Topo IB signature motif; other site
1198114001698	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1198114001699	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114001700	active site
1198114001701	Int/Topo IB signature motif; other site
1198114001702	DNA binding site [nucleotide binding]
1198114001703	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1198114001704	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1198114001705	DNA methylase; Region: N6_N4_Mtase; pfam01555
1198114001706	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1198114001707	DNA methylase; Region: N6_N4_Mtase; pfam01555
1198114001708	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1198114001709	Part of AAA domain; Region: AAA_19; pfam13245
1198114001710	Family description; Region: UvrD_C_2; pfam13538
1198114001711	Uncharacterized conserved protein [Function unknown]; Region: COG1751
1198114001712	Pathogenicity locus; Region: Cdd1; pfam11731
1198114001713	Uncharacterized phage-associated protein [Function unknown]; Region: GepA; COG3600
1198114001714	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114001715	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114001716	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114001717	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1198114001718	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1198114001719	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1198114001720	Transposase; Region: HTH_Tnp_1; cl17663
1198114001721	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1198114001722	active site
1198114001723	SUMO-1 interface [polypeptide binding]; other site
1198114001724	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114001725	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114001726	active site
1198114001727	catalytic tetrad [active]
1198114001728	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114001729	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1198114001730	NAD(P) binding site [chemical binding]; other site
1198114001731	active site
1198114001732	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114001733	SnoaL-like domain; Region: SnoaL_2; pfam12680
1198114001734	Cupin; Region: Cupin_6; pfam12852
1198114001735	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114001736	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1198114001737	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114001738	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1198114001739	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114001740	putative substrate translocation pore; other site
1198114001741	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1198114001742	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1198114001743	[4Fe-4S] binding site [ion binding]; other site
1198114001744	molybdopterin cofactor binding site; other site
1198114001745	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1198114001746	molybdopterin cofactor binding site; other site
1198114001747	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1198114001748	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1198114001749	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
1198114001750	Flavodoxin; Region: Flavodoxin_1; pfam00258
1198114001751	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1198114001752	FAD binding pocket [chemical binding]; other site
1198114001753	FAD binding motif [chemical binding]; other site
1198114001754	catalytic residues [active]
1198114001755	NAD binding pocket [chemical binding]; other site
1198114001756	phosphate binding motif [ion binding]; other site
1198114001757	beta-alpha-beta structure motif; other site
1198114001758	ferredoxin-nitrite reductase; Reviewed; Region: nirA; PRK09567
1198114001759	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1198114001760	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1198114001761	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
1198114001762	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1198114001763	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1198114001764	active site
1198114001765	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114001766	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1198114001767	ANTAR domain; Region: ANTAR; pfam03861
1198114001768	alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777
1198114001769	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1198114001770	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
1198114001771	FAD binding pocket [chemical binding]; other site
1198114001772	phosphate binding motif [ion binding]; other site
1198114001773	beta-alpha-beta structure motif; other site
1198114001774	NAD binding pocket [chemical binding]; other site
1198114001775	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114001776	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114001777	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
1198114001778	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1198114001779	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1198114001780	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114001781	NAD(P) binding site [chemical binding]; other site
1198114001782	active site
1198114001783	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114001784	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114001785	active site
1198114001786	catalytic tetrad [active]
1198114001787	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1198114001788	classical (c) SDRs; Region: SDR_c; cd05233
1198114001789	NAD(P) binding site [chemical binding]; other site
1198114001790	active site
1198114001791	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1198114001792	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1198114001793	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1198114001794	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FkbH; COG3882
1198114001795	Acid Phosphatase; Region: Acid_PPase; cl17256
1198114001796	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1198114001797	(R)-hydratase [(R)-specific enoyl-CoA hydratase]. Catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway.  The structure of the monomer includes a five-strand antiparallel...; Region: R_hydratase_like; cd03441
1198114001798	active site
1198114001799	catalytic site [active]
1198114001800	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114001801	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114001802	Sulfatase; Region: Sulfatase; cl17466
1198114001803	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1198114001804	Predicted integral membrane protein [Function unknown]; Region: COG5652
1198114001805	Acetokinase family; Region: Acetate_kinase; cl17229
1198114001806	propionate/acetate kinase; Provisional; Region: PRK12379
1198114001807	PAS fold; Region: PAS_2; pfam08446
1198114001808	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1198114001809	Phytochrome region; Region: PHY; pfam00360
1198114001810	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1198114001811	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1198114001812	NAD binding site [chemical binding]; other site
1198114001813	homotetramer interface [polypeptide binding]; other site
1198114001814	homodimer interface [polypeptide binding]; other site
1198114001815	substrate binding site [chemical binding]; other site
1198114001816	active site
1198114001817	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1198114001818	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1198114001819	substrate binding site; other site
1198114001820	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1198114001821	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1198114001822	inhibitor-cofactor binding pocket; inhibition site
1198114001823	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114001824	catalytic residue [active]
1198114001825	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA; cl00391
1198114001826	active site clefts [active]
1198114001827	zinc binding site [ion binding]; other site
1198114001828	dimer interface [polypeptide binding]; other site
1198114001829	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
1198114001830	conserved cys residue [active]
1198114001831	HD domain; Region: HD_5; pfam13487
1198114001832	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1198114001833	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1198114001834	Zn2+ binding site [ion binding]; other site
1198114001835	Mg2+ binding site [ion binding]; other site
1198114001836	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1198114001837	Two component regulator propeller; Region: Reg_prop; pfam07494
1198114001838	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1198114001839	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114001840	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114001841	metal binding site [ion binding]; metal-binding site
1198114001842	active site
1198114001843	I-site; other site
1198114001844	Flavoprotein; Region: Flavoprotein; pfam02441
1198114001845	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1198114001846	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1198114001847	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1198114001848	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1198114001849	active site
1198114001850	ATP-binding site [chemical binding]; other site
1198114001851	pantoate-binding site; other site
1198114001852	HXXH motif; other site
1198114001853	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1198114001854	active site
1198114001855	oligomerization interface [polypeptide binding]; other site
1198114001856	metal binding site [ion binding]; metal-binding site
1198114001857	Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cl00149
1198114001858	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114001859	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114001860	active site
1198114001861	Phosphoesterase family; Region: Phosphoesterase; pfam04185
1198114001862	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114001863	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114001864	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114001865	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1198114001866	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114001867	ATP binding site [chemical binding]; other site
1198114001868	Mg2+ binding site [ion binding]; other site
1198114001869	G-X-G motif; other site
1198114001870	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1198114001871	anti sigma factor interaction site; other site
1198114001872	regulatory phosphorylation site [posttranslational modification]; other site
1198114001873	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114001874	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114001875	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114001876	metal binding site [ion binding]; metal-binding site
1198114001877	Pyridoxamine 5'-phosphate oxidase; Region: Pyrid_oxidase_2; pfam13883
1198114001878	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
1198114001879	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114001880	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114001881	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1198114001882	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1198114001883	DNA binding site [nucleotide binding]
1198114001884	domain linker motif; other site
1198114001885	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1198114001886	dimerization interface [polypeptide binding]; other site
1198114001887	ligand binding site [chemical binding]; other site
1198114001888	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
1198114001889	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
1198114001890	Putative glucoamylase; Region: Glycoamylase; pfam10091
1198114001891	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1198114001892	RNA binding surface [nucleotide binding]; other site
1198114001893	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114001894	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114001895	active site
1198114001896	catalytic triad [active]
1198114001897	calcium binding site [ion binding]; other site
1198114001898	multicopper oxidase; Provisional; Region: PRK10965
1198114001899	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1198114001900	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1198114001901	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1198114001902	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1198114001903	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1198114001904	Active Sites [active]
1198114001905	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1198114001906	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1198114001907	CysD dimerization site [polypeptide binding]; other site
1198114001908	G1 box; other site
1198114001909	putative GEF interaction site [polypeptide binding]; other site
1198114001910	GTP/Mg2+ binding site [chemical binding]; other site
1198114001911	Switch I region; other site
1198114001912	G2 box; other site
1198114001913	G3 box; other site
1198114001914	Switch II region; other site
1198114001915	G4 box; other site
1198114001916	G5 box; other site
1198114001917	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1198114001918	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1198114001919	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1198114001920	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1198114001921	Active Sites [active]
1198114001922	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114001923	short chain dehydrogenase; Provisional; Region: PRK06180
1198114001924	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1198114001925	NADP binding site [chemical binding]; other site
1198114001926	active site
1198114001927	steroid binding site; other site
1198114001928	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114001929	peptidase domain interface [polypeptide binding]; other site
1198114001930	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114001931	active site
1198114001932	catalytic triad [active]
1198114001933	calcium binding site [ion binding]; other site
1198114001934	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1198114001935	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1198114001936	Ligand binding site; other site
1198114001937	Putative Catalytic site; other site
1198114001938	DXD motif; other site
1198114001939	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1198114001940	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114001941	NAD(P) binding site [chemical binding]; other site
1198114001942	active site
1198114001943	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
1198114001944	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1198114001945	PYR/PP interface [polypeptide binding]; other site
1198114001946	dimer interface [polypeptide binding]; other site
1198114001947	TPP binding site [chemical binding]; other site
1198114001948	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1198114001949	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
1198114001950	TPP-binding site [chemical binding]; other site
1198114001951	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1198114001952	active site
1198114001953	NAD binding site [chemical binding]; other site
1198114001954	metal binding site [ion binding]; metal-binding site
1198114001955	classical (c) SDRs; Region: SDR_c; cd05233
1198114001956	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1198114001957	NAD(P) binding site [chemical binding]; other site
1198114001958	active site
1198114001959	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1198114001960	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114001961	S-adenosylmethionine binding site [chemical binding]; other site
1198114001962	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1198114001963	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1198114001964	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1198114001965	Cupin domain; Region: Cupin_2; pfam07883
1198114001966	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1198114001967	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1198114001968	PA14 domain; Region: PA14; cl08459
1198114001969	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1198114001970	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114001971	Predicted extracellular nuclease [General function prediction only]; Region: COG2374
1198114001972	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
1198114001973	generic binding surface I; other site
1198114001974	generic binding surface II; other site
1198114001975	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1198114001976	putative catalytic site [active]
1198114001977	putative metal binding site [ion binding]; other site
1198114001978	putative phosphate binding site [ion binding]; other site
1198114001979	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1198114001980	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114001981	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1198114001982	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1198114001983	Ca binding site [ion binding]; other site
1198114001984	active site
1198114001985	catalytic site [active]
1198114001986	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114001987	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1198114001988	putative substrate translocation pore; other site
1198114001989	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114001990	Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Region: PulA; COG1523
1198114001991	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1198114001992	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1198114001993	active site
1198114001994	catalytic site [active]
1198114001995	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1198114001996	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1198114001997	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114001998	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114001999	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114002000	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114002001	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114002002	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114002003	Amidase; Region: Amidase; pfam01425
1198114002004	Beta-propeller repeat; Region: SBBP; pfam06739
1198114002005	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114002006	Cyclomaltodextrinase, N-terminal; Region: Cyc-maltodext_N; pfam09087
1198114002007	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1198114002008	trehalose synthase; Region: treS_nterm; TIGR02456
1198114002009	active site
1198114002010	catalytic site [active]
1198114002011	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114002012	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114002013	DNA binding site [nucleotide binding]
1198114002014	photolyase PhrII; Region: phr2; TIGR00591
1198114002015	DNA photolyase; Region: DNA_photolyase; pfam00875
1198114002016	Xylose isomerase [Carbohydrate transport and metabolism]; Region: XylA; cl09945
1198114002017	GAF domain; Region: GAF; pfam01590
1198114002018	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114002019	PAS fold; Region: PAS_4; pfam08448
1198114002020	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1198114002021	putative active site [active]
1198114002022	heme pocket [chemical binding]; other site
1198114002023	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114002024	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114002025	metal binding site [ion binding]; metal-binding site
1198114002026	active site
1198114002027	I-site; other site
1198114002028	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
1198114002029	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
1198114002030	NAD binding site [chemical binding]; other site
1198114002031	substrate binding site [chemical binding]; other site
1198114002032	homodimer interface [polypeptide binding]; other site
1198114002033	active site
1198114002034	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
1198114002035	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1198114002036	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1198114002037	HI0933-like protein; Region: HI0933_like; pfam03486
1198114002038	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1198114002039	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1198114002040	putative RNA binding site [nucleotide binding]; other site
1198114002041	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114002042	S-adenosylmethionine binding site [chemical binding]; other site
1198114002043	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1198114002044	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1198114002045	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1198114002046	dimer interface [polypeptide binding]; other site
1198114002047	motif 1; other site
1198114002048	active site
1198114002049	motif 2; other site
1198114002050	motif 3; other site
1198114002051	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1198114002052	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114002053	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
1198114002054	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_4; cd06241
1198114002055	putative active site [active]
1198114002056	Zn binding site [ion binding]; other site
1198114002057	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1198114002058	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1198114002059	NodB motif; other site
1198114002060	active site
1198114002061	catalytic site [active]
1198114002062	metal binding site [ion binding]; metal-binding site
1198114002063	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1198114002064	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1198114002065	catalytic triad [active]
1198114002066	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1198114002067	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1198114002068	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114002069	RNA polymerase factor sigma-70; Validated; Region: PRK09047
1198114002070	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114002071	DNA binding residues [nucleotide binding]
1198114002072	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
1198114002073	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114002074	Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504
1198114002075	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1198114002076	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1198114002077	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1198114002078	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
1198114002079	trimer interface [polypeptide binding]; other site
1198114002080	active site
1198114002081	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
1198114002082	catalytic site [active]
1198114002083	Antitoxin ParD; Region: ParD; pfam09386
1198114002084	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1198114002085	CTP synthetase; Validated; Region: pyrG; PRK05380
1198114002086	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1198114002087	Catalytic site [active]
1198114002088	active site
1198114002089	UTP binding site [chemical binding]; other site
1198114002090	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1198114002091	active site
1198114002092	putative oxyanion hole; other site
1198114002093	catalytic triad [active]
1198114002094	HEPN domain; Region: HEPN; cl00824
1198114002095	hypothetical protein; Reviewed; Region: PRK12497
1198114002096	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1198114002097	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1198114002098	tetrameric interface [polypeptide binding]; other site
1198114002099	NAD binding site [chemical binding]; other site
1198114002100	catalytic residues [active]
1198114002101	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
1198114002102	catalytic residues [active]
1198114002103	DinB superfamily; Region: DinB_2; pfam12867
1198114002104	hypothetical protein; Provisional; Region: PRK06062
1198114002105	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1198114002106	inhibitor-cofactor binding pocket; inhibition site
1198114002107	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114002108	catalytic residue [active]
1198114002109	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485
1198114002110	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1198114002111	Na binding site [ion binding]; other site
1198114002112	putative substrate binding site [chemical binding]; other site
1198114002113	phenylhydantoinase; Validated; Region: PRK08323
1198114002114	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
1198114002115	tetramer interface [polypeptide binding]; other site
1198114002116	active site
1198114002117	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1198114002118	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1198114002119	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1198114002120	homodimer interface [polypeptide binding]; other site
1198114002121	active site
1198114002122	FMN binding site [chemical binding]; other site
1198114002123	substrate binding site [chemical binding]; other site
1198114002124	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1198114002125	4Fe-4S binding domain; Region: Fer4; pfam00037
1198114002126	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1198114002127	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1198114002128	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114002129	allantoate amidohydrolase; Reviewed; Region: PRK09290
1198114002130	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1198114002131	active site
1198114002132	metal binding site [ion binding]; metal-binding site
1198114002133	dimer interface [polypeptide binding]; other site
1198114002134	Uncharacterized conserved protein [Function unknown]; Region: COG4104
1198114002135	BtpA family; Region: BtpA; cl00440
1198114002136	Helix-turn-helix domain; Region: HTH_17; pfam12728
1198114002137	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114002138	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1198114002139	catalytic residues [active]
1198114002140	catalytic nucleophile [active]
1198114002141	Recombinase; Region: Recombinase; pfam07508
1198114002142	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114002143	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114002144	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114002145	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1198114002146	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1198114002147	NAD binding site [chemical binding]; other site
1198114002148	substrate binding site [chemical binding]; other site
1198114002149	homodimer interface [polypeptide binding]; other site
1198114002150	active site
1198114002151	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1198114002152	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1198114002153	substrate binding site; other site
1198114002154	tetramer interface; other site
1198114002155	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1198114002156	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1198114002157	NADP binding site [chemical binding]; other site
1198114002158	active site
1198114002159	putative substrate binding site [chemical binding]; other site
1198114002160	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1198114002161	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
1198114002162	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1198114002163	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114002164	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
1198114002165	putative ADP-binding pocket [chemical binding]; other site
1198114002166	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1198114002167	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1198114002168	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114002169	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1198114002170	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114002171	TPR motif; other site
1198114002172	binding surface
1198114002173	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1198114002174	Peptidase M15; Region: Peptidase_M15_3; cl01194
1198114002175	Protein of unknown function, DUF480; Region: DUF480; pfam04337
1198114002176	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1198114002177	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1198114002178	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1198114002179	DNA primase; Validated; Region: dnaG; PRK05667
1198114002180	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1198114002181	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1198114002182	active site
1198114002183	metal binding site [ion binding]; metal-binding site
1198114002184	interdomain interaction site; other site
1198114002185	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1198114002186	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1198114002187	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1198114002188	oligomer interface [polypeptide binding]; other site
1198114002189	active site
1198114002190	metal binding site [ion binding]; metal-binding site
1198114002191	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1198114002192	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1198114002193	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1198114002194	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114002195	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114002196	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114002197	active site
1198114002198	phosphorylation site [posttranslational modification]
1198114002199	intermolecular recognition site; other site
1198114002200	dimerization interface [polypeptide binding]; other site
1198114002201	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114002202	DNA binding residues [nucleotide binding]
1198114002203	dimerization interface [polypeptide binding]; other site
1198114002204	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1198114002205	Histidine kinase; Region: HisKA_3; pfam07730
1198114002206	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1198114002207	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1198114002208	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1198114002209	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1198114002210	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1198114002211	Walker A/P-loop; other site
1198114002212	ATP binding site [chemical binding]; other site
1198114002213	Q-loop/lid; other site
1198114002214	ABC transporter signature motif; other site
1198114002215	Walker B; other site
1198114002216	D-loop; other site
1198114002217	H-loop/switch region; other site
1198114002218	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114002219	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114002220	active site
1198114002221	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
1198114002222	Y-family of DNA polymerases; Region: PolY; cd00424
1198114002223	active site
1198114002224	DNA binding site [nucleotide binding]
1198114002225	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1198114002226	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114002227	active site
1198114002228	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1198114002229	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114002230	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
1198114002231	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1198114002232	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1198114002233	B12 binding site [chemical binding]; other site
1198114002234	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1198114002235	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1198114002236	FeS/SAM binding site; other site
1198114002237	Domain of unknown function (DUF4070); Region: DUF4070; pfam13282
1198114002238	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1198114002239	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1198114002240	substrate binding site [chemical binding]; other site
1198114002241	dimer interface [polypeptide binding]; other site
1198114002242	ATP binding site [chemical binding]; other site
1198114002243	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1198114002244	Protein export membrane protein; Region: SecD_SecF; cl14618
1198114002245	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1198114002246	Protein export membrane protein; Region: SecD_SecF; cl14618
1198114002247	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114002248	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114002249	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114002250	hypothetical protein; Validated; Region: PRK08238
1198114002251	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324
1198114002252	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
1198114002253	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1198114002254	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1198114002255	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1198114002256	active site
1198114002257	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
1198114002258	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1198114002259	5S rRNA interface [nucleotide binding]; other site
1198114002260	CTC domain interface [polypeptide binding]; other site
1198114002261	L16 interface [polypeptide binding]; other site
1198114002262	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1198114002263	putative active site [active]
1198114002264	catalytic residue [active]
1198114002265	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1198114002266	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1198114002267	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1198114002268	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1198114002269	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1198114002270	short chain dehydrogenase; Provisional; Region: PRK06180
1198114002271	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1198114002272	NADP binding site [chemical binding]; other site
1198114002273	active site
1198114002274	steroid binding site; other site
1198114002275	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114002276	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114002277	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
1198114002278	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114002279	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114002280	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1198114002281	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114002282	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114002283	DNA binding residues [nucleotide binding]
1198114002284	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1198114002285	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1198114002286	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1198114002287	AP (apurinic/apyrimidinic) site pocket; other site
1198114002288	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1198114002289	DNA interaction; other site
1198114002290	Metal-binding active site; metal-binding site
1198114002291	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1198114002292	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1198114002293	Dimer interface [polypeptide binding]; other site
1198114002294	anticodon binding site; other site
1198114002295	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1198114002296	homodimer interface [polypeptide binding]; other site
1198114002297	motif 1; other site
1198114002298	motif 2; other site
1198114002299	active site
1198114002300	motif 3; other site
1198114002301	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA; cl00391
1198114002302	dimer interface [polypeptide binding]; other site
1198114002303	active site clefts [active]
1198114002304	zinc binding site [ion binding]; other site
1198114002305	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114002306	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1198114002307	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114002308	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1198114002309	putative dimerization interface [polypeptide binding]; other site
1198114002310	Predicted membrane protein [Function unknown]; Region: COG2855
1198114002311	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114002312	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114002313	active site
1198114002314	catalytic tetrad [active]
1198114002315	The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524
1198114002316	putative amphipathic alpha helix; other site
1198114002317	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1198114002318	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1198114002319	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1198114002320	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114002321	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114002322	metal binding site [ion binding]; metal-binding site
1198114002323	active site
1198114002324	I-site; other site
1198114002325	Domain of unknown function (DUF305); Region: DUF305; pfam03713
1198114002326	choice-of-anchor B domain; Region: choice_anch_B; TIGR04312
1198114002327	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); Region: NT5C; cl17836
1198114002328	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1198114002329	Putative zinc ribbon domain; Region: DUF164; pfam02591
1198114002330	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1198114002331	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1198114002332	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1198114002333	active site
1198114002334	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1198114002335	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1198114002336	active site
1198114002337	tetramer interface; other site
1198114002338	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
1198114002339	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1198114002340	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114002341	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1198114002342	active site
1198114002343	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1198114002344	active site
1198114002345	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1198114002346	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1198114002347	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114002348	ATP binding site [chemical binding]; other site
1198114002349	putative Mg++ binding site [ion binding]; other site
1198114002350	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114002351	nucleotide binding region [chemical binding]; other site
1198114002352	ATP-binding site [chemical binding]; other site
1198114002353	TRCF domain; Region: TRCF; pfam03461
1198114002354	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
1198114002355	X-Pro dipeptidyl-peptidase (S15 family); Region: Peptidase_S15; pfam02129
1198114002356	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114002357	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1198114002358	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114002359	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114002360	DNA binding residues [nucleotide binding]
1198114002361	Putative zinc-finger; Region: zf-HC2; pfam13490
1198114002362	HEAT repeats; Region: HEAT_2; pfam13646
1198114002363	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1198114002364	protein binding site [polypeptide binding]; other site
1198114002365	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1198114002366	protein binding site [polypeptide binding]; other site
1198114002367	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cd01635
1198114002368	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114002369	GAF domain; Region: GAF_2; pfam13185
1198114002370	GAF domain; Region: GAF_3; pfam13492
1198114002371	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1198114002372	aminodeoxychorismate synthase; Provisional; Region: PRK07508
1198114002373	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1198114002374	hypothetical protein; Provisional; Region: PRK07546
1198114002375	substrate-cofactor binding pocket; other site
1198114002376	homodimer interface [polypeptide binding]; other site
1198114002377	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1198114002378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114002379	catalytic residue [active]
1198114002380	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1198114002381	Cytochrome P450; Region: p450; cl12078
1198114002382	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1198114002383	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002384	FeS/SAM binding site; other site
1198114002385	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114002386	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
1198114002387	PA/protease or protease-like domain interface [polypeptide binding]; other site
1198114002388	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
1198114002389	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114002390	metal binding site [ion binding]; metal-binding site
1198114002391	enterobactin exporter EntS; Provisional; Region: PRK10489
1198114002392	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114002393	putative substrate translocation pore; other site
1198114002394	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1198114002395	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
1198114002396	catalytic residues [active]
1198114002397	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114002398	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114002399	active site
1198114002400	catalytic tetrad [active]
1198114002401	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114002402	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1198114002403	FtsX-like permease family; Region: FtsX; pfam02687
1198114002404	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114002405	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114002406	Walker A/P-loop; other site
1198114002407	ATP binding site [chemical binding]; other site
1198114002408	Q-loop/lid; other site
1198114002409	ABC transporter signature motif; other site
1198114002410	Walker B; other site
1198114002411	D-loop; other site
1198114002412	H-loop/switch region; other site
1198114002413	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1198114002414	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114002415	ligand binding site [chemical binding]; other site
1198114002416	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1198114002417	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
1198114002418	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114002419	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
1198114002420	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1198114002421	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114002422	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114002423	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114002424	Uncharacterized protein conserved in bacteria (DUF2251); Region: DUF2251; cl01770
1198114002425	threonine dehydratase; Provisional; Region: PRK08198
1198114002426	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1198114002427	tetramer interface [polypeptide binding]; other site
1198114002428	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114002429	catalytic residue [active]
1198114002430	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
1198114002431	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1198114002432	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1198114002433	CoA-binding site [chemical binding]; other site
1198114002434	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
1198114002435	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1198114002436	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1198114002437	homodimer interface [polypeptide binding]; other site
1198114002438	NADP binding site [chemical binding]; other site
1198114002439	substrate binding site [chemical binding]; other site
1198114002440	Trm112p-like protein; Region: Trm112p; cl01066
1198114002441	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1198114002442	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
1198114002443	nucleophile elbow; other site
1198114002444	Surface antigen; Region: Bac_surface_Ag; pfam01103
1198114002445	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1198114002446	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
1198114002447	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1198114002448	oligomeric interface; other site
1198114002449	putative active site [active]
1198114002450	homodimer interface [polypeptide binding]; other site
1198114002451	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1198114002452	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1198114002453	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1198114002454	minor groove reading motif; other site
1198114002455	helix-hairpin-helix signature motif; other site
1198114002456	substrate binding pocket [chemical binding]; other site
1198114002457	active site
1198114002458	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
1198114002459	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1198114002460	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1198114002461	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1198114002462	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
1198114002463	four helix bundle protein; Region: TIGR02436
1198114002464	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1198114002465	active site
1198114002466	HslU subunit interaction site [polypeptide binding]; other site
1198114002467	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1198114002468	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1198114002469	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114002470	Walker A motif; other site
1198114002471	ATP binding site [chemical binding]; other site
1198114002472	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1198114002473	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1198114002474	ATP-dependent DNA ligase; Reviewed; Region: ligC; PRK08224
1198114002475	Adenylation domain of Mycobacterium tuberculosis LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigC; cd07905
1198114002476	active site
1198114002477	DNA binding site [nucleotide binding]
1198114002478	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigC is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigC; cd07970
1198114002479	DNA binding site [nucleotide binding]
1198114002480	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
1198114002481	nucleotide binding site [chemical binding]; other site
1198114002482	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1198114002483	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1198114002484	RNA binding surface [nucleotide binding]; other site
1198114002485	Fic/DOC family; Region: Fic; pfam02661
1198114002486	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1198114002487	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1198114002488	Catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases; Region: CE4_NodB_like_1; cd10960
1198114002489	NodB motif; other site
1198114002490	putative active site [active]
1198114002491	putative catalytic site [active]
1198114002492	putative Zn binding site [ion binding]; other site
1198114002493	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114002494	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114002495	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114002496	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114002497	Tannase and feruloyl esterase; Region: Tannase; pfam07519
1198114002498	transaldolase-like protein; Provisional; Region: PTZ00411
1198114002499	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1198114002500	active site
1198114002501	dimer interface [polypeptide binding]; other site
1198114002502	catalytic residue [active]
1198114002503	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1198114002504	Interdomain contacts; other site
1198114002505	Cytokine receptor motif; other site
1198114002506	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1198114002507	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114002508	non-specific DNA binding site [nucleotide binding]; other site
1198114002509	salt bridge; other site
1198114002510	sequence-specific DNA binding site [nucleotide binding]; other site
1198114002511	Cupin domain; Region: Cupin_2; pfam07883
1198114002512	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_8; cd07817
1198114002513	putative hydrophobic ligand binding site [chemical binding]; other site
1198114002514	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1198114002515	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1198114002516	NAD binding site [chemical binding]; other site
1198114002517	catalytic Zn binding site [ion binding]; other site
1198114002518	structural Zn binding site [ion binding]; other site
1198114002519	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1198114002520	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1198114002521	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1198114002522	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1198114002523	Glycoside hydrolase family 15, N-terminal domain; Region: GH15_N; cd07430
1198114002524	Domain interface; other site
1198114002525	glucan 1,4-alpha-glucosidase; Region: glucan_glucosid; TIGR01535
1198114002526	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1198114002527	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1198114002528	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1198114002529	TPP-binding site [chemical binding]; other site
1198114002530	dimer interface [polypeptide binding]; other site
1198114002531	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1198114002532	PYR/PP interface [polypeptide binding]; other site
1198114002533	dimer interface [polypeptide binding]; other site
1198114002534	TPP binding site [chemical binding]; other site
1198114002535	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1198114002536	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1198114002537	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1198114002538	active site
1198114002539	dimer interface [polypeptide binding]; other site
1198114002540	short chain dehydrogenase; Provisional; Region: PRK06180
1198114002541	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1198114002542	NADP binding site [chemical binding]; other site
1198114002543	active site
1198114002544	steroid binding site; other site
1198114002545	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1198114002546	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114002547	motif II; other site
1198114002548	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1198114002549	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1198114002550	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1198114002551	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1198114002552	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
1198114002553	putative active site [active]
1198114002554	Glucokinase; Region: Glucokinase; pfam02685
1198114002555	glucokinase, proteobacterial type; Region: glk; TIGR00749
1198114002556	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1198114002557	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114002558	S-adenosylmethionine binding site [chemical binding]; other site
1198114002559	Peptidase family M1; Region: Peptidase_M1; pfam01433
1198114002560	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
1198114002561	Zn binding site [ion binding]; other site
1198114002562	Domain of unknown function (DUF3358); Region: DUF3358; pfam11838
1198114002563	Histidinol phosphatase and related phosphatases [Amino acid transport and metabolism]; Region: HisB; COG0241
1198114002564	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114002565	active site
1198114002566	motif I; other site
1198114002567	motif II; other site
1198114002568	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1198114002569	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1198114002570	putative active site [active]
1198114002571	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1198114002572	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
1198114002573	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
1198114002574	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
1198114002575	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1198114002576	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114002577	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114002578	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114002579	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1198114002580	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1198114002581	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114002582	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1198114002583	dimerization interface [polypeptide binding]; other site
1198114002584	substrate binding pocket [chemical binding]; other site
1198114002585	putative acetyltransferase; Provisional; Region: PRK03624
1198114002586	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114002587	Coenzyme A binding pocket [chemical binding]; other site
1198114002588	Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase) and related proteins; Region: AmyAc_OligoGlu_like; cd11331
1198114002589	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1198114002590	active site
1198114002591	catalytic site [active]
1198114002592	PAS domain S-box; Region: sensory_box; TIGR00229
1198114002593	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1198114002594	putative active site [active]
1198114002595	heme pocket [chemical binding]; other site
1198114002596	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114002597	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114002598	metal binding site [ion binding]; metal-binding site
1198114002599	active site
1198114002600	I-site; other site
1198114002601	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114002602	Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847
1198114002603	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
1198114002604	Flp pilus assembly protein CpaB [Intracellular trafficking and secretion]; Region: CpaB; COG3745
1198114002605	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1198114002606	Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964
1198114002607	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
1198114002608	BON domain; Region: BON; pfam04972
1198114002609	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1198114002610	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1198114002611	active site
1198114002612	dimerization interface [polypeptide binding]; other site
1198114002613	AAA domain; Region: AAA_31; pfam13614
1198114002614	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1198114002615	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
1198114002616	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1198114002617	ATP binding site [chemical binding]; other site
1198114002618	Walker A motif; other site
1198114002619	hexamer interface [polypeptide binding]; other site
1198114002620	Walker B motif; other site
1198114002621	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
1198114002622	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
1198114002623	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1198114002624	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114002625	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114002626	DNA binding residues [nucleotide binding]
1198114002627	dimerization interface [polypeptide binding]; other site
1198114002628	Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847
1198114002629	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
1198114002630	PAS domain S-box; Region: sensory_box; TIGR00229
1198114002631	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114002632	putative active site [active]
1198114002633	heme pocket [chemical binding]; other site
1198114002634	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114002635	metal binding site [ion binding]; metal-binding site
1198114002636	active site
1198114002637	I-site; other site
1198114002638	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114002639	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
1198114002640	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114002641	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114002642	metal binding site [ion binding]; metal-binding site
1198114002643	active site
1198114002644	I-site; other site
1198114002645	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
1198114002646	Domain of unknown function (DUF4112); Region: DUF4112; pfam13430
1198114002647	Protein of unknown function DUF72; Region: DUF72; pfam01904
1198114002648	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
1198114002649	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1198114002650	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FkbH; COG3882
1198114002651	Acid Phosphatase; Region: Acid_PPase; cl17256
1198114002652	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1198114002653	(R)-hydratase [(R)-specific enoyl-CoA hydratase] catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. (R)-hydratase contains a hot-dog fold similar to those of thioesterase...; Region: R_hydratase; cd03449
1198114002654	dimer interaction site [polypeptide binding]; other site
1198114002655	substrate-binding tunnel; other site
1198114002656	active site
1198114002657	catalytic site [active]
1198114002658	substrate binding site [chemical binding]; other site
1198114002659	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1198114002660	classical (c) SDRs; Region: SDR_c; cd05233
1198114002661	NAD(P) binding site [chemical binding]; other site
1198114002662	active site
1198114002663	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114002664	Family description; Region: VCBS; pfam13517
1198114002665	Family description; Region: VCBS; pfam13517
1198114002666	Family description; Region: VCBS; pfam13517
1198114002667	Family description; Region: VCBS; pfam13517
1198114002668	Family description; Region: VCBS; pfam13517
1198114002669	Family description; Region: VCBS; pfam13517
1198114002670	Family description; Region: VCBS; pfam13517
1198114002671	Family description; Region: VCBS; pfam13517
1198114002672	Family description; Region: VCBS; pfam13517
1198114002673	Family description; Region: VCBS; pfam13517
1198114002674	Family description; Region: VCBS; pfam13517
1198114002675	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1198114002676	Phosphoesterase family; Region: Phosphoesterase; pfam04185
1198114002677	Phosphoesterase family; Region: Phosphoesterase; pfam04185
1198114002678	Phosphoesterase family; Region: Phosphoesterase; pfam04185
1198114002679	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
1198114002680	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1198114002681	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1198114002682	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1198114002683	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1198114002684	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1198114002685	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1198114002686	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114002687	putative substrate translocation pore; other site
1198114002688	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1198114002689	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1198114002690	FAD binding site [chemical binding]; other site
1198114002691	homotetramer interface [polypeptide binding]; other site
1198114002692	substrate binding pocket [chemical binding]; other site
1198114002693	catalytic base [active]
1198114002694	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1198114002695	DNA binding residues [nucleotide binding]
1198114002696	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114002697	binding surface
1198114002698	TPR motif; other site
1198114002699	TPR repeat; Region: TPR_11; pfam13414
1198114002700	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1198114002701	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1198114002702	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002703	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114002704	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114002705	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002706	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002707	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002708	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002709	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1198114002710	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1198114002711	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002712	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002713	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1198114002714	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002715	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002716	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
1198114002717	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1198114002718	Outer membrane efflux protein; Region: OEP; pfam02321
1198114002719	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114002720	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114002721	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1198114002722	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1198114002723	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114002724	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114002725	active site
1198114002726	phosphorylation site [posttranslational modification]
1198114002727	intermolecular recognition site; other site
1198114002728	dimerization interface [polypeptide binding]; other site
1198114002729	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114002730	DNA binding site [nucleotide binding]
1198114002731	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114002732	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1198114002733	dimerization interface [polypeptide binding]; other site
1198114002734	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114002735	dimer interface [polypeptide binding]; other site
1198114002736	phosphorylation site [posttranslational modification]
1198114002737	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114002738	ATP binding site [chemical binding]; other site
1198114002739	Mg2+ binding site [ion binding]; other site
1198114002740	G-X-G motif; other site
1198114002741	Short chain fatty acids transporter [Lipid metabolism]; Region: AtoE; COG2031
1198114002742	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1198114002743	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114002744	dimer interface [polypeptide binding]; other site
1198114002745	phosphorylation site [posttranslational modification]
1198114002746	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114002747	ATP binding site [chemical binding]; other site
1198114002748	Mg2+ binding site [ion binding]; other site
1198114002749	G-X-G motif; other site
1198114002750	PBP superfamily domain; Region: PBP_like_2; pfam12849
1198114002751	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114002752	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114002753	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1198114002754	AMIN domain; Region: AMIN; pfam11741
1198114002755	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1198114002756	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1198114002757	active site
1198114002758	metal binding site [ion binding]; metal-binding site
1198114002759	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1198114002760	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1198114002761	motif 1; other site
1198114002762	active site
1198114002763	motif 2; other site
1198114002764	motif 3; other site
1198114002765	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1198114002766	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
1198114002767	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1198114002768	putative active site [active]
1198114002769	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1198114002770	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1198114002771	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114002772	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114002773	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114002774	dimer interface [polypeptide binding]; other site
1198114002775	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114002776	ATP binding site [chemical binding]; other site
1198114002777	Mg2+ binding site [ion binding]; other site
1198114002778	G-X-G motif; other site
1198114002779	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1198114002780	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1198114002781	active site
1198114002782	comF family protein; Region: comF; TIGR00201
1198114002783	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1198114002784	active site
1198114002785	OPT oligopeptide transporter protein; Region: OPT; cl14607
1198114002786	OPT oligopeptide transporter protein; Region: OPT; cl14607
1198114002787	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
1198114002788	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1198114002789	EamA-like transporter family; Region: EamA; pfam00892
1198114002790	EamA-like transporter family; Region: EamA; pfam00892
1198114002791	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1198114002792	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002793	FeS/SAM binding site; other site
1198114002794	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1198114002795	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114002796	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1198114002797	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114002798	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114002799	metal binding site [ion binding]; metal-binding site
1198114002800	active site
1198114002801	I-site; other site
1198114002802	PAS fold; Region: PAS_4; pfam08448
1198114002803	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114002804	putative active site [active]
1198114002805	heme pocket [chemical binding]; other site
1198114002806	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114002807	PAS domain; Region: PAS_9; pfam13426
1198114002808	putative active site [active]
1198114002809	heme pocket [chemical binding]; other site
1198114002810	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114002811	dimer interface [polypeptide binding]; other site
1198114002812	phosphorylation site [posttranslational modification]
1198114002813	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114002814	Mg2+ binding site [ion binding]; other site
1198114002815	G-X-G motif; other site
1198114002816	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114002817	putative substrate translocation pore; other site
1198114002818	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114002819	Peptidase family M50; Region: Peptidase_M50; pfam02163
1198114002820	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1198114002821	active site
1198114002822	putative substrate binding region [chemical binding]; other site
1198114002823	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1198114002824	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1198114002825	active site
1198114002826	HIGH motif; other site
1198114002827	dimer interface [polypeptide binding]; other site
1198114002828	KMSKS motif; other site
1198114002829	ScpA/B protein; Region: ScpA_ScpB; cl00598
1198114002830	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1198114002831	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1198114002832	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1198114002833	Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612
1198114002834	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
1198114002835	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1198114002836	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1198114002837	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1198114002838	RNA binding surface [nucleotide binding]; other site
1198114002839	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1198114002840	active site
1198114002841	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1198114002842	transmembrane helices; other site
1198114002843	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1198114002844	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114002845	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114002846	active site
1198114002847	phosphorylation site [posttranslational modification]
1198114002848	intermolecular recognition site; other site
1198114002849	dimerization interface [polypeptide binding]; other site
1198114002850	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114002851	DNA binding residues [nucleotide binding]
1198114002852	dimerization interface [polypeptide binding]; other site
1198114002853	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1198114002854	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1198114002855	Interdomain contacts; other site
1198114002856	Cytokine receptor motif; other site
1198114002857	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1198114002858	Histidine kinase; Region: HisKA_3; pfam07730
1198114002859	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114002860	ATP binding site [chemical binding]; other site
1198114002861	Mg2+ binding site [ion binding]; other site
1198114002862	G-X-G motif; other site
1198114002863	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114002864	S-adenosylmethionine binding site [chemical binding]; other site
1198114002865	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
1198114002866	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002867	FeS/SAM binding site; other site
1198114002868	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1198114002869	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1198114002870	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114002871	S-adenosylmethionine binding site [chemical binding]; other site
1198114002872	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1198114002873	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
1198114002874	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114002875	active site
1198114002876	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
1198114002877	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002878	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1198114002879	FeS/SAM binding site; other site
1198114002880	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1198114002881	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114002882	S-adenosylmethionine binding site [chemical binding]; other site
1198114002883	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1198114002884	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114002885	S-adenosylmethionine binding site [chemical binding]; other site
1198114002886	B12 binding domain; Region: B12-binding; pfam02310
1198114002887	B12 binding site [chemical binding]; other site
1198114002888	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002889	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1198114002890	FeS/SAM binding site; other site
1198114002891	B12 binding domain; Region: B12-binding; pfam02310
1198114002892	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1198114002893	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002894	FeS/SAM binding site; other site
1198114002895	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
1198114002896	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1198114002897	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002898	FeS/SAM binding site; other site
1198114002899	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
1198114002900	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1198114002901	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114002902	FeS/SAM binding site; other site
1198114002903	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1198114002904	active site
1198114002905	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
1198114002906	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114002907	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1198114002908	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1198114002909	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114002910	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1198114002911	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1198114002912	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1198114002913	metal-binding site
1198114002914	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1198114002915	O-Antigen ligase; Region: Wzy_C; pfam04932
1198114002916	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1198114002917	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1198114002918	Chain length determinant protein; Region: Wzz; cl15801
1198114002919	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsE; COG3524
1198114002920	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1198114002921	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
1198114002922	SLBB domain; Region: SLBB; pfam10531
1198114002923	SLBB domain; Region: SLBB; pfam10531
1198114002924	SLBB domain; Region: SLBB; pfam10531
1198114002925	Cytochrome c; Region: Cytochrom_C; pfam00034
1198114002926	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1198114002927	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
1198114002928	Plastocyanin [Energy production and conversion]; Region: PetE; COG3794
1198114002929	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1198114002930	dimerization interface [polypeptide binding]; other site
1198114002931	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114002932	dimer interface [polypeptide binding]; other site
1198114002933	phosphorylation site [posttranslational modification]
1198114002934	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1198114002935	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114002936	ATP binding site [chemical binding]; other site
1198114002937	Mg2+ binding site [ion binding]; other site
1198114002938	G-X-G motif; other site
1198114002939	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114002940	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114002941	active site
1198114002942	phosphorylation site [posttranslational modification]
1198114002943	intermolecular recognition site; other site
1198114002944	dimerization interface [polypeptide binding]; other site
1198114002945	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114002946	DNA binding site [nucleotide binding]
1198114002947	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1198114002948	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1198114002949	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
1198114002950	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1198114002951	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
1198114002952	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1198114002953	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
1198114002954	phosphopeptide binding site; other site
1198114002955	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1198114002956	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1198114002957	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1198114002958	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1198114002959	active site
1198114002960	ATP binding site [chemical binding]; other site
1198114002961	substrate binding site [chemical binding]; other site
1198114002962	activation loop (A-loop); other site
1198114002963	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114002964	TPR motif; other site
1198114002965	binding surface
1198114002966	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114002967	TPR motif; other site
1198114002968	binding surface
1198114002969	TPR repeat; Region: TPR_11; pfam13414
1198114002970	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114002971	binding surface
1198114002972	TPR repeat; Region: TPR_11; pfam13414
1198114002973	TPR motif; other site
1198114002974	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
1198114002975	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114002976	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114002977	metal binding site [ion binding]; metal-binding site
1198114002978	active site
1198114002979	I-site; other site
1198114002980	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114002981	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1198114002982	Homoserine acetyltransferase [Amino acid transport and metabolism]; Region: MET2; COG2021
1198114002983	amidase; Provisional; Region: PRK08137
1198114002984	Amidase; Region: Amidase; pfam01425
1198114002985	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114002986	peptidase domain interface [polypeptide binding]; other site
1198114002987	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114002988	active site
1198114002989	catalytic triad [active]
1198114002990	calcium binding site [ion binding]; other site
1198114002991	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
1198114002992	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1198114002993	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1198114002994	active site
1198114002995	catalytic triad [active]
1198114002996	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1198114002997	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1198114002998	active site
1198114002999	catalytic triad [active]
1198114003000	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1198114003001	active site
1198114003002	catalytic triad [active]
1198114003003	rhamnose-proton symporter; Provisional; Region: PRK13499
1198114003004	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1198114003005	Cysteine-rich domain; Region: CCG; pfam02754
1198114003006	Cysteine-rich domain; Region: CCG; pfam02754
1198114003007	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
1198114003008	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1198114003009	4Fe-4S binding domain; Region: Fer4; cl02805
1198114003010	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; cl00674
1198114003011	L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype; Region: L_rham_iso_rhiz; TIGR02629
1198114003012	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1198114003013	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
1198114003014	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1198114003015	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1198114003016	ligand binding site [chemical binding]; other site
1198114003017	short chain dehydrogenase; Validated; Region: PRK08324
1198114003018	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
1198114003019	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114003020	NAD(P) binding site [chemical binding]; other site
1198114003021	active site
1198114003022	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
1198114003023	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1198114003024	nucleotide binding site [chemical binding]; other site
1198114003025	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1198114003026	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114003027	S-adenosylmethionine binding site [chemical binding]; other site
1198114003028	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1198114003029	Sulfatase; Region: Sulfatase; cl17466
1198114003030	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1198114003031	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1198114003032	active site
1198114003033	catalytic site [active]
1198114003034	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1198114003035	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1198114003036	Penicillin amidase; Region: Penicil_amidase; pfam01804
1198114003037	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1198114003038	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1198114003039	active site
1198114003040	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1198114003041	DNA primase large subunit; Validated; Region: PRK02249
1198114003042	Protein of unknown function (DUF3050); Region: DUF3050; pfam11251
1198114003043	Protein of unknown function (DUF971); Region: DUF971; pfam06155
1198114003044	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1198114003045	hypothetical protein; Provisional; Region: PRK10621
1198114003046	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1198114003047	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1198114003048	Walker A/P-loop; other site
1198114003049	ATP binding site [chemical binding]; other site
1198114003050	Q-loop/lid; other site
1198114003051	ABC transporter signature motif; other site
1198114003052	Walker B; other site
1198114003053	D-loop; other site
1198114003054	H-loop/switch region; other site
1198114003055	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1198114003056	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114003057	Amidase; Region: Amidase; pfam01425
1198114003058	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1198114003059	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1198114003060	dimer interface [polypeptide binding]; other site
1198114003061	anticodon binding site; other site
1198114003062	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1198114003063	homodimer interface [polypeptide binding]; other site
1198114003064	motif 1; other site
1198114003065	active site
1198114003066	motif 2; other site
1198114003067	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1198114003068	active site
1198114003069	motif 3; other site
1198114003070	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114003071	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114003072	atypical (a) SDRs, subgroup 7; Region: SDR_a7; cd05262
1198114003073	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1198114003074	putative NAD(P) binding site [chemical binding]; other site
1198114003075	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1198114003076	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
1198114003077	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1198114003078	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
1198114003079	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1198114003080	Clp amino terminal domain; Region: Clp_N; pfam02861
1198114003081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114003082	Walker A motif; other site
1198114003083	ATP binding site [chemical binding]; other site
1198114003084	Walker B motif; other site
1198114003085	arginine finger; other site
1198114003086	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114003087	Walker A motif; other site
1198114003088	ATP binding site [chemical binding]; other site
1198114003089	Walker B motif; other site
1198114003090	arginine finger; other site
1198114003091	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1198114003092	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114003093	hypothetical protein; Provisional; Region: PRK07208
1198114003094	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
1198114003095	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
1198114003096	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1198114003097	Moco binding site; other site
1198114003098	metal coordination site [ion binding]; other site
1198114003099	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114003100	dimer interface [polypeptide binding]; other site
1198114003101	phosphorylation site [posttranslational modification]
1198114003102	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114003103	ATP binding site [chemical binding]; other site
1198114003104	Mg2+ binding site [ion binding]; other site
1198114003105	G-X-G motif; other site
1198114003106	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
1198114003107	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1198114003108	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114003109	S-adenosylmethionine binding site [chemical binding]; other site
1198114003110	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114003111	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1198114003112	active site
1198114003113	active site
1198114003114	metal binding site [ion binding]; metal-binding site
1198114003115	Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681
1198114003116	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1198114003117	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1198114003118	RF-1 domain; Region: RF-1; pfam00472
1198114003119	DNA ligase I, ATP-dependent (dnl1); Region: dnl1; TIGR00574
1198114003120	Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases; Region: Adenylation_DNA_ligase_like; cl12015
1198114003121	active site
1198114003122	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of archaeal and bacterial ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_Arch_LigB; cd07972
1198114003123	DNA binding site [nucleotide binding]
1198114003124	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1198114003125	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1198114003126	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114003127	catalytic residue [active]
1198114003128	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1198114003129	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1198114003130	substrate binding site [chemical binding]; other site
1198114003131	active site
1198114003132	catalytic residues [active]
1198114003133	heterodimer interface [polypeptide binding]; other site
1198114003134	Chorismate mutase type II; Region: CM_2; smart00830
1198114003135	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
1198114003136	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1198114003137	VbhA antitoxin and related proteins; Region: VbhA_like; cd11586
1198114003138	FIC domain binding interface [polypeptide binding]; other site
1198114003139	Fic/DOC family; Region: Fic; cl00960
1198114003140	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
1198114003141	prephenate dehydrogenase; Validated; Region: PRK08507
1198114003142	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1198114003143	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114003144	putative substrate translocation pore; other site
1198114003145	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114003146	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1198114003147	MarR family; Region: MarR_2; pfam12802
1198114003148	PAS domain; Region: PAS; smart00091
1198114003149	PAS fold; Region: PAS_4; pfam08448
1198114003150	PAS fold; Region: PAS_4; pfam08448
1198114003151	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114003152	dimer interface [polypeptide binding]; other site
1198114003153	phosphorylation site [posttranslational modification]
1198114003154	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114003155	ATP binding site [chemical binding]; other site
1198114003156	Mg2+ binding site [ion binding]; other site
1198114003157	G-X-G motif; other site
1198114003158	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1198114003159	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1198114003160	protein binding site [polypeptide binding]; other site
1198114003161	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_2; cd06160
1198114003162	Peptidase family M50; Region: Peptidase_M50; pfam02163
1198114003163	active site
1198114003164	putative substrate binding region [chemical binding]; other site
1198114003165	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1198114003166	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1198114003167	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1198114003168	classical (c) SDRs; Region: SDR_c; cd05233
1198114003169	NAD(P) binding site [chemical binding]; other site
1198114003170	active site
1198114003171	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1198114003172	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1198114003173	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1198114003174	active site
1198114003175	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
1198114003176	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1198114003177	Protein of unknown function (DUF1009); Region: DUF1009; pfam06230
1198114003178	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1198114003179	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114003180	catalytic triad [active]
1198114003181	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1198114003182	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1198114003183	catalytic residue [active]
1198114003184	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1198114003185	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1198114003186	GTP-binding protein LepA; Provisional; Region: PRK05433
1198114003187	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1198114003188	G1 box; other site
1198114003189	putative GEF interaction site [polypeptide binding]; other site
1198114003190	GTP/Mg2+ binding site [chemical binding]; other site
1198114003191	Switch I region; other site
1198114003192	G2 box; other site
1198114003193	G3 box; other site
1198114003194	Switch II region; other site
1198114003195	G4 box; other site
1198114003196	G5 box; other site
1198114003197	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1198114003198	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1198114003199	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1198114003200	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1198114003201	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1198114003202	nucleotide binding site/active site [active]
1198114003203	HIT family signature motif; other site
1198114003204	catalytic residue [active]
1198114003205	Peptidase family M48; Region: Peptidase_M48; cl12018
1198114003206	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1198114003207	tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs; Region: THN_reductase-like_SDR_c; cd05362
1198114003208	NADP binding site [chemical binding]; other site
1198114003209	homodimer interface [polypeptide binding]; other site
1198114003210	active site
1198114003211	substrate binding site [chemical binding]; other site
1198114003212	Putative modulator of DNA gyrase; Region: PmbA_TldD; pfam01523
1198114003213	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1198114003214	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1198114003215	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1198114003216	E3 interaction surface; other site
1198114003217	lipoyl attachment site [posttranslational modification]; other site
1198114003218	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114003219	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1198114003220	Outer membrane efflux protein; Region: OEP; pfam02321
1198114003221	Outer membrane efflux protein; Region: OEP; pfam02321
1198114003222	CHASE3 domain; Region: CHASE3; pfam05227
1198114003223	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114003224	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114003225	dimer interface [polypeptide binding]; other site
1198114003226	phosphorylation site [posttranslational modification]
1198114003227	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114003228	ATP binding site [chemical binding]; other site
1198114003229	Mg2+ binding site [ion binding]; other site
1198114003230	G-X-G motif; other site
1198114003231	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114003232	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114003233	active site
1198114003234	phosphorylation site [posttranslational modification]
1198114003235	intermolecular recognition site; other site
1198114003236	dimerization interface [polypeptide binding]; other site
1198114003237	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1198114003238	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114003239	active site
1198114003240	phosphorylation site [posttranslational modification]
1198114003241	intermolecular recognition site; other site
1198114003242	dimerization interface [polypeptide binding]; other site
1198114003243	PAS domain; Region: PAS; smart00091
1198114003244	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114003245	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114003246	dimer interface [polypeptide binding]; other site
1198114003247	phosphorylation site [posttranslational modification]
1198114003248	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114003249	ATP binding site [chemical binding]; other site
1198114003250	Mg2+ binding site [ion binding]; other site
1198114003251	G-X-G motif; other site
1198114003252	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_3; cd09602
1198114003253	aminopeptidase N, Streptomyces lividans type; Region: pepN_strep_liv; TIGR02412
1198114003254	Zn binding site [ion binding]; other site
1198114003255	Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BcsA; COG3424
1198114003256	Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy; Region: CHS_like; cd00831
1198114003257	malonyl-CoA binding site [chemical binding]; other site
1198114003258	dimer interface [polypeptide binding]; other site
1198114003259	active site
1198114003260	product binding site; other site
1198114003261	acyl carrier protein; Provisional; Region: acpP; PRK00982
1198114003262	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1198114003263	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1198114003264	dimer interface [polypeptide binding]; other site
1198114003265	active site
1198114003266	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114003267	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1198114003268	putative metal binding site; other site
1198114003269	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1198114003270	Catalase-like heme-binding proteins and protein domains; Region: catalase_like; cl09506
1198114003271	heme binding pocket [chemical binding]; other site
1198114003272	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1198114003273	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1198114003274	domain interactions; other site
1198114003275	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1198114003276	active site
1198114003277	catalytic triad [active]
1198114003278	oxyanion hole [active]
1198114003279	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1198114003280	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1198114003281	glutaminase active site [active]
1198114003282	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1198114003283	active site
1198114003284	dimer interface [polypeptide binding]; other site
1198114003285	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1198114003286	dimer interface [polypeptide binding]; other site
1198114003287	active site
1198114003288	AIPR protein; Region: AIPR; pfam10592
1198114003289	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114003290	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114003291	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114003292	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114003293	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114003294	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114003295	Fic/DOC family; Region: Fic; pfam02661
1198114003296	Fic family protein [Function unknown]; Region: COG3177
1198114003297	BON domain; Region: BON; pfam04972
1198114003298	BON domain; Region: BON; pfam04972
1198114003299	Protein of unknown function, DUF481; Region: DUF481; cl01213
1198114003300	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114003301	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114003302	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114003303	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
1198114003304	CGNR zinc finger; Region: zf-CGNR; pfam11706
1198114003305	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114003306	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1198114003307	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1198114003308	putative peroxiredoxin; Provisional; Region: PRK13190
1198114003309	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1198114003310	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
1198114003311	dimer interface [polypeptide binding]; other site
1198114003312	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1198114003313	catalytic triad [active]
1198114003314	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1198114003315	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1198114003316	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114003317	active site
1198114003318	phosphorylation site [posttranslational modification]
1198114003319	intermolecular recognition site; other site
1198114003320	dimerization interface [polypeptide binding]; other site
1198114003321	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1198114003322	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1198114003323	ssDNA binding site; other site
1198114003324	generic binding surface II; other site
1198114003325	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114003326	ATP binding site [chemical binding]; other site
1198114003327	putative Mg++ binding site [ion binding]; other site
1198114003328	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114003329	nucleotide binding region [chemical binding]; other site
1198114003330	ATP-binding site [chemical binding]; other site
1198114003331	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1198114003332	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1198114003333	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1198114003334	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114003335	Walker A/P-loop; other site
1198114003336	ATP binding site [chemical binding]; other site
1198114003337	Q-loop/lid; other site
1198114003338	ABC transporter signature motif; other site
1198114003339	Walker B; other site
1198114003340	D-loop; other site
1198114003341	H-loop/switch region; other site
1198114003342	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1198114003343	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1198114003344	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1198114003345	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1198114003346	putative acyl-acceptor binding pocket; other site
1198114003347	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1198114003348	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1198114003349	5'-3' exonuclease; Region: 53EXOc; smart00475
1198114003350	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1198114003351	active site
1198114003352	metal binding site 1 [ion binding]; metal-binding site
1198114003353	putative 5' ssDNA interaction site; other site
1198114003354	metal binding site 3; metal-binding site
1198114003355	metal binding site 2 [ion binding]; metal-binding site
1198114003356	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1198114003357	putative DNA binding site [nucleotide binding]; other site
1198114003358	putative metal binding site [ion binding]; other site
1198114003359	DNA polymerase I - 3'-5' exonuclease and polymerase domains [DNA replication, recombination, and repair]; Region: PolA; COG0749
1198114003360	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
1198114003361	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1198114003362	active site
1198114003363	DNA binding site [nucleotide binding]
1198114003364	catalytic site [active]
1198114003365	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114003366	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1198114003367	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
1198114003368	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
1198114003369	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1198114003370	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
1198114003371	homotetramer interface [polypeptide binding]; other site
1198114003372	ligand binding site [chemical binding]; other site
1198114003373	catalytic site [active]
1198114003374	NAD binding site [chemical binding]; other site
1198114003375	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114003376	DNA-binding site [nucleotide binding]; DNA binding site
1198114003377	RNA-binding motif; other site
1198114003378	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114003379	Protein of unknown function (DUF3738); Region: DUF3738; cl11887
1198114003380	Motility quorum-sensing regulator (MqsR); Region: MqsR; cd12869
1198114003381	peptide binding site [polypeptide binding]; other site
1198114003382	antitoxin MqsA for MqsR toxin; Region: MqsA; cd12870
1198114003383	toxin interface [polypeptide binding]; other site
1198114003384	putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830
1198114003385	Zn binding site [ion binding]; other site
1198114003386	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114003387	non-specific DNA binding site [nucleotide binding]; other site
1198114003388	salt bridge; other site
1198114003389	sequence-specific DNA binding site [nucleotide binding]; other site
1198114003390	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1198114003391	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1198114003392	tetramer interface [polypeptide binding]; other site
1198114003393	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114003394	catalytic residue [active]
1198114003395	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114003396	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114003397	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1198114003398	Predicted membrane protein [Function unknown]; Region: COG4818
1198114003399	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1198114003400	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114003401	putative substrate translocation pore; other site
1198114003402	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1198114003403	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1198114003404	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1198114003405	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1198114003406	DNA binding site [nucleotide binding]
1198114003407	active site
1198114003408	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1198114003409	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1198114003410	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
1198114003411	Transglycosylase; Region: Transgly; pfam00912
1198114003412	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1198114003413	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1198114003414	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1198114003415	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1198114003416	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1198114003417	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1198114003418	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114003419	TIGR03663 family protein; Region: TIGR03663
1198114003420	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1198114003421	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114003422	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
1198114003423	beta-D-glucuronidase; Provisional; Region: PRK10150
1198114003424	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1198114003425	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1198114003426	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1198114003427	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1198114003428	dimerization interface [polypeptide binding]; other site
1198114003429	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1198114003430	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1198114003431	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
1198114003432	GIY-YIG motif/motif A; other site
1198114003433	putative active site [active]
1198114003434	putative metal binding site [ion binding]; other site
1198114003435	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1198114003436	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114003437	ATP binding site [chemical binding]; other site
1198114003438	putative Mg++ binding site [ion binding]; other site
1198114003439	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114003440	nucleotide binding region [chemical binding]; other site
1198114003441	ATP-binding site [chemical binding]; other site
1198114003442	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1198114003443	putative nucleotide binding site [chemical binding]; other site
1198114003444	uridine monophosphate binding site [chemical binding]; other site
1198114003445	homohexameric interface [polypeptide binding]; other site
1198114003446	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114003447	3-carboxymuconate cyclase [Carbohydrate transport and metabolism]; Region: COG2706
1198114003448	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1198114003449	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1198114003450	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1198114003451	active site
1198114003452	Zn binding site [ion binding]; other site
1198114003453	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1198114003454	mce related protein; Region: MCE; pfam02470
1198114003455	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1198114003456	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
1198114003457	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114003458	putative catalytic residue [active]
1198114003459	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114003460	peptidase domain interface [polypeptide binding]; other site
1198114003461	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114003462	active site
1198114003463	catalytic triad [active]
1198114003464	calcium binding site [ion binding]; other site
1198114003465	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1198114003466	active site
1198114003467	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1198114003468	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
1198114003469	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1198114003470	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1198114003471	Walker A/P-loop; other site
1198114003472	ATP binding site [chemical binding]; other site
1198114003473	Q-loop/lid; other site
1198114003474	ABC transporter signature motif; other site
1198114003475	Walker B; other site
1198114003476	D-loop; other site
1198114003477	H-loop/switch region; other site
1198114003478	MarR family; Region: MarR_2; cl17246
1198114003479	vitamin B12-dependent ribonucleotide reductase; Validated; Region: PRK06556
1198114003480	Class II vitamin B12-dependent ribonucleotide reductase; Region: Ribonuc_red_2_N; pfam08471
1198114003481	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
1198114003482	active site
1198114003483	dimer interface [polypeptide binding]; other site
1198114003484	effector binding site; other site
1198114003485	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1198114003486	TSCPD domain; Region: TSCPD; pfam12637
1198114003487	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114003488	Walker A/P-loop; other site
1198114003489	ATP binding site [chemical binding]; other site
1198114003490	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114003491	Walker B; other site
1198114003492	D-loop; other site
1198114003493	H-loop/switch region; other site
1198114003494	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1198114003495	active site
1198114003496	metal binding site [ion binding]; metal-binding site
1198114003497	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114003498	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114003499	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114003500	NIPSNAP; Region: NIPSNAP; pfam07978
1198114003501	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1198114003502	AAA domain; Region: AAA_31; pfam13614
1198114003503	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1198114003504	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1198114003505	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114003506	Walker A/P-loop; other site
1198114003507	ATP binding site [chemical binding]; other site
1198114003508	Q-loop/lid; other site
1198114003509	ABC transporter signature motif; other site
1198114003510	Walker B; other site
1198114003511	D-loop; other site
1198114003512	H-loop/switch region; other site
1198114003513	Transglutaminase-like superfamily; Region: Transglut_core3; pfam13471
1198114003514	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1198114003515	ligand-binding site [chemical binding]; other site
1198114003516	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
1198114003517	HprK-related kinase A; Region: HprK_rel_A; TIGR04352
1198114003518	Putative 2OG-Fe(II) oxygenase; Region: 2OG-FeII_Oxy_5; pfam13759
1198114003519	SynChlorMet cassette protein ScmC; Region: SCM_chp_ScmC; TIGR04249
1198114003520	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
1198114003521	active site
1198114003522	metal-binding site [ion binding]
1198114003523	nucleotide-binding site [chemical binding]; other site
1198114003524	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
1198114003525	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1198114003526	Ligand Binding Site [chemical binding]; other site
1198114003527	Molecular Tunnel; other site
1198114003528	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1198114003529	nudix motif; other site
1198114003530	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1198114003531	active site
1198114003532	metal binding site A [ion binding]; metal-binding site
1198114003533	DNA binding site [nucleotide binding]
1198114003534	putative catalytic site [active]
1198114003535	putative phosphate binding site [ion binding]; other site
1198114003536	putative AP binding site [nucleotide binding]; other site
1198114003537	putative metal binding site B [ion binding]; other site
1198114003538	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1198114003539	active site
1198114003540	DNA polymerase IV; Validated; Region: PRK02406
1198114003541	DNA binding site [nucleotide binding]
1198114003542	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1198114003543	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1198114003544	Lhr-like helicases [General function prediction only]; Region: Lhr; COG1201
1198114003545	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114003546	ATP binding site [chemical binding]; other site
1198114003547	putative Mg++ binding site [ion binding]; other site
1198114003548	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114003549	nucleotide binding region [chemical binding]; other site
1198114003550	ATP-binding site [chemical binding]; other site
1198114003551	DEAD/H associated; Region: DEAD_assoc; pfam08494
1198114003552	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114003553	binding surface
1198114003554	TPR motif; other site
1198114003555	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1198114003556	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114003557	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114003558	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114003559	CCC1; Region: CCC1; cd02435
1198114003560	Integral membrane protein TerC family; Region: TerC; cl10468
1198114003561	Protein of unknown function (DUF3761); Region: DUF3761; pfam12587
1198114003562	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114003563	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114003564	metal binding site [ion binding]; metal-binding site
1198114003565	Sec-independent protein translocase protein (TatC); Region: TatC; pfam00902
1198114003566	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1198114003567	quinolinate synthetase; Provisional; Region: PRK09375
1198114003568	Uncharacterized conserved protein (DUF2203); Region: DUF2203; cl02056
1198114003569	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114003570	S-adenosylmethionine binding site [chemical binding]; other site
1198114003571	ergothioneine biosynthesis protein EgtB; Region: egtB_TIGR03440
1198114003572	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1198114003573	dimethylhistidine N-methyltransferase; Region: egtD_ergothio; TIGR03438
1198114003574	Uncharacterized conserved protein (DUF2260); Region: DUF2260; pfam10017
1198114003575	MoaC family. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine derivative to the precursor...; Region: MoaC; cl00242
1198114003576	trimer interface [polypeptide binding]; other site
1198114003577	dimer interface [polypeptide binding]; other site
1198114003578	putative active site [active]
1198114003579	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1198114003580	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1198114003581	dimer interface [polypeptide binding]; other site
1198114003582	putative functional site; other site
1198114003583	putative MPT binding site; other site
1198114003584	TPR repeat; Region: TPR_11; pfam13414
1198114003585	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114003586	binding surface
1198114003587	TPR motif; other site
1198114003588	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1198114003589	Ligand Binding Site [chemical binding]; other site
1198114003590	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
1198114003591	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
1198114003592	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1198114003593	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1198114003594	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1198114003595	putative active site [active]
1198114003596	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1198114003597	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
1198114003598	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1198114003599	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1198114003600	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114003601	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1198114003602	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114003603	Coenzyme A binding pocket [chemical binding]; other site
1198114003604	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1198114003605	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1198114003606	Glucose inhibited division protein A; Region: GIDA; pfam01134
1198114003607	GTP-binding protein Der; Reviewed; Region: PRK00093
1198114003608	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1198114003609	G1 box; other site
1198114003610	GTP/Mg2+ binding site [chemical binding]; other site
1198114003611	Switch I region; other site
1198114003612	G2 box; other site
1198114003613	Switch II region; other site
1198114003614	G3 box; other site
1198114003615	G4 box; other site
1198114003616	G5 box; other site
1198114003617	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1198114003618	G1 box; other site
1198114003619	GTP/Mg2+ binding site [chemical binding]; other site
1198114003620	Switch I region; other site
1198114003621	G2 box; other site
1198114003622	G3 box; other site
1198114003623	Switch II region; other site
1198114003624	G4 box; other site
1198114003625	G5 box; other site
1198114003626	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
1198114003627	dimer interface [polypeptide binding]; other site
1198114003628	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114003629	ligand binding site [chemical binding]; other site
1198114003630	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1198114003631	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1198114003632	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1198114003633	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114003634	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1198114003635	active site
1198114003636	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, gammaproteobacterial type; Region: rSAM_QueE_gams; TIGR04349
1198114003637	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1198114003638	Purine nucleoside permease (NUP); Region: NUP; cl17832
1198114003639	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
1198114003640	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114003641	active site
1198114003642	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1198114003643	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cd06551
1198114003644	putative acyl-acceptor binding pocket; other site
1198114003645	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
1198114003646	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114003647	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1198114003648	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1198114003649	NAD(P) binding site [chemical binding]; other site
1198114003650	catalytic residues [active]
1198114003651	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114003652	phytoene desaturase; Region: crtI_fam; TIGR02734
1198114003653	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
1198114003654	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114003655	putative homodimer interface [polypeptide binding]; other site
1198114003656	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1198114003657	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114003658	UDP-galactopyranose mutase; Region: GLF; pfam03275
1198114003659	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
1198114003660	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114003661	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114003662	active site
1198114003663	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1198114003664	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1198114003665	active site
1198114003666	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1198114003667	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1198114003668	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114003669	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114003670	metal binding site [ion binding]; metal-binding site
1198114003671	active site
1198114003672	I-site; other site
1198114003673	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114003674	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1198114003675	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1198114003676	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1198114003677	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114003678	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114003679	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114003680	metal binding site [ion binding]; metal-binding site
1198114003681	active site
1198114003682	I-site; other site
1198114003683	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114003684	TIGR01777 family protein; Region: yfcH
1198114003685	NAD(P) binding site [chemical binding]; other site
1198114003686	active site
1198114003687	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1198114003688	hydrophobic ligand binding site; other site
1198114003689	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
1198114003690	putative hydrophobic ligand binding site [chemical binding]; other site
1198114003691	Protein of unknown function (DUF796); Region: DUF796; cl01226
1198114003692	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1198114003693	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like6; cd05664
1198114003694	metal binding site [ion binding]; metal-binding site
1198114003695	putative dimer interface [polypeptide binding]; other site
1198114003696	Uncharacterized protein conserved in bacteria (DUF2062); Region: DUF2062; cl01261
1198114003697	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1198114003698	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1198114003699	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114003700	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114003701	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114003702	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114003703	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114003704	active site
1198114003705	phosphorylation site [posttranslational modification]
1198114003706	intermolecular recognition site; other site
1198114003707	dimerization interface [polypeptide binding]; other site
1198114003708	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114003709	Walker A motif; other site
1198114003710	ATP binding site [chemical binding]; other site
1198114003711	Walker B motif; other site
1198114003712	arginine finger; other site
1198114003713	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114003714	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1198114003715	dimerization interface [polypeptide binding]; other site
1198114003716	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1198114003717	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114003718	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114003719	dimer interface [polypeptide binding]; other site
1198114003720	phosphorylation site [posttranslational modification]
1198114003721	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114003722	ATP binding site [chemical binding]; other site
1198114003723	Mg2+ binding site [ion binding]; other site
1198114003724	G-X-G motif; other site
1198114003725	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1198114003726	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1198114003727	hexamer interface [polypeptide binding]; other site
1198114003728	ligand binding site [chemical binding]; other site
1198114003729	putative active site [active]
1198114003730	NAD(P) binding site [chemical binding]; other site
1198114003731	rod shape-determining protein MreB; Provisional; Region: PRK13927
1198114003732	MreB and similar proteins; Region: MreB_like; cd10225
1198114003733	nucleotide binding site [chemical binding]; other site
1198114003734	Mg binding site [ion binding]; other site
1198114003735	putative protofilament interaction site [polypeptide binding]; other site
1198114003736	RodZ interaction site [polypeptide binding]; other site
1198114003737	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
1198114003738	Putative esterase; Region: Esterase; pfam00756
1198114003739	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1198114003740	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1198114003741	Cytochrome P450; Region: p450; cl12078
1198114003742	rod shape-determining protein MreC; Provisional; Region: PRK13922
1198114003743	rod shape-determining protein MreC; Region: MreC; pfam04085
1198114003744	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
1198114003745	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1198114003746	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1198114003747	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1198114003748	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1198114003749	Zn binding site [ion binding]; other site
1198114003750	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1198114003751	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1198114003752	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1198114003753	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1198114003754	substrate binding pocket [chemical binding]; other site
1198114003755	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114003756	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114003757	KH domain; Region: KH_4; pfam13083
1198114003758	PAS domain; Region: PAS_9; pfam13426
1198114003759	PAS fold; Region: PAS_4; pfam08448
1198114003760	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1198114003761	RNA binding site [nucleotide binding]; other site
1198114003762	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1198114003763	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1198114003764	Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex; Region: CESA_CaSu_A2; cd06437
1198114003765	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1198114003766	DXD motif; other site
1198114003767	menaquinone biosynthesis protein, SCO4550 family; Region: mena_SCO4550; TIGR03699
1198114003768	Vitamin K epoxide reductase family in bacteria and plants; Region: VKOR_1; cd12916
1198114003769	putative active site [active]
1198114003770	substrate binding site [chemical binding]; other site
1198114003771	redox center [active]
1198114003772	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1198114003773	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114003774	S-adenosylmethionine binding site [chemical binding]; other site
1198114003775	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1198114003776	Protein phosphatase 2C; Region: PP2C; pfam00481
1198114003777	active site
1198114003778	YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function.  YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase.   Other enzymes with this fold include the peroxisomal...; Region: YdeM; cd03454
1198114003779	putative active site [active]
1198114003780	putative catalytic site [active]
1198114003781	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1198114003782	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1198114003783	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1198114003784	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114003785	non-specific DNA binding site [nucleotide binding]; other site
1198114003786	salt bridge; other site
1198114003787	sequence-specific DNA binding site [nucleotide binding]; other site
1198114003788	Protein of unknown function (DUF419); Region: DUF419; pfam04237
1198114003789	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1198114003790	elongation factor Tu; Reviewed; Region: PRK00049
1198114003791	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1198114003792	G1 box; other site
1198114003793	GEF interaction site [polypeptide binding]; other site
1198114003794	GTP/Mg2+ binding site [chemical binding]; other site
1198114003795	Switch I region; other site
1198114003796	G2 box; other site
1198114003797	G3 box; other site
1198114003798	Switch II region; other site
1198114003799	G4 box; other site
1198114003800	G5 box; other site
1198114003801	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1198114003802	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1198114003803	Antibiotic Binding Site [chemical binding]; other site
1198114003804	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114003805	putative active site [active]
1198114003806	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1198114003807	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
1198114003808	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1198114003809	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1198114003810	putative homodimer interface [polypeptide binding]; other site
1198114003811	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1198114003812	heterodimer interface [polypeptide binding]; other site
1198114003813	homodimer interface [polypeptide binding]; other site
1198114003814	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1198114003815	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1198114003816	23S rRNA interface [nucleotide binding]; other site
1198114003817	L7/L12 interface [polypeptide binding]; other site
1198114003818	putative thiostrepton binding site; other site
1198114003819	L25 interface [polypeptide binding]; other site
1198114003820	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114003821	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1198114003822	FeS/SAM binding site; other site
1198114003823	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114003824	putative active site [active]
1198114003825	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114003826	putative active site [active]
1198114003827	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1198114003828	mRNA/rRNA interface [nucleotide binding]; other site
1198114003829	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1198114003830	23S rRNA interface [nucleotide binding]; other site
1198114003831	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1198114003832	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1198114003833	L11 interface [polypeptide binding]; other site
1198114003834	putative EF-Tu interaction site [polypeptide binding]; other site
1198114003835	putative EF-G interaction site [polypeptide binding]; other site
1198114003836	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1198114003837	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1198114003838	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1198114003839	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1198114003840	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
1198114003841	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1198114003842	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1198114003843	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1198114003844	RPB3 interaction site [polypeptide binding]; other site
1198114003845	RPB1 interaction site [polypeptide binding]; other site
1198114003846	RPB11 interaction site [polypeptide binding]; other site
1198114003847	RPB10 interaction site [polypeptide binding]; other site
1198114003848	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1198114003849	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1198114003850	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1198114003851	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1198114003852	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1198114003853	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1198114003854	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1198114003855	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1198114003856	DNA binding site [nucleotide binding]
1198114003857	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1198114003858	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
1198114003859	putative active site [active]
1198114003860	DNA phosphorothioation-associated DGQHR protein 1; Region: DGQHR_dnd_1; TIGR04172
1198114003861	DGQHR domain; Region: DGQHR; TIGR03187
1198114003862	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
1198114003863	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
1198114003864	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1198114003865	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1198114003866	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1198114003867	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1198114003868	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
1198114003869	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1198114003870	Walker A motif; other site
1198114003871	ATP binding site [chemical binding]; other site
1198114003872	Walker B motif; other site
1198114003873	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1198114003874	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1198114003875	chaperone protein DnaJ; Provisional; Region: PRK14278
1198114003876	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1198114003877	HSP70 interaction site [polypeptide binding]; other site
1198114003878	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1198114003879	Zn binding sites [ion binding]; other site
1198114003880	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1198114003881	dimer interface [polypeptide binding]; other site
1198114003882	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1198114003883	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114003884	non-specific DNA binding site [nucleotide binding]; other site
1198114003885	salt bridge; other site
1198114003886	sequence-specific DNA binding site [nucleotide binding]; other site
1198114003887	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1198114003888	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
1198114003889	N-terminal domain of the actinomycetal Nei1 and related DNA glycosylases; Region: AcNei1_N; cd08970
1198114003890	putative DNA binding site [nucleotide binding]; other site
1198114003891	catalytic residue [active]
1198114003892	putative H2TH interface [polypeptide binding]; other site
1198114003893	putative catalytic residues [active]
1198114003894	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1198114003895	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1198114003896	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1198114003897	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1198114003898	nucleotide binding site [chemical binding]; other site
1198114003899	NEF interaction site [polypeptide binding]; other site
1198114003900	SBD interface [polypeptide binding]; other site
1198114003901	Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. They break the catechol C1-C2 bond and utilize Fe3+, as opposed to  the...; Region: intradiol_dioxygenase_like; cd03457
1198114003902	putative active site [active]
1198114003903	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
1198114003904	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1198114003905	classical (c) SDRs; Region: SDR_c; cd05233
1198114003906	NAD(P) binding site [chemical binding]; other site
1198114003907	active site
1198114003908	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
1198114003909	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1198114003910	DNA binding residues [nucleotide binding]
1198114003911	hopanoid biosynthesis associated glycosyl transferase protein HpnI; Region: HpnI; TIGR03472
1198114003912	Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520
1198114003913	ligand binding site; other site
1198114003914	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1198114003915	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
1198114003916	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
1198114003917	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1198114003918	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1198114003919	nucleotide binding site [chemical binding]; other site
1198114003920	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1198114003921	catalytic core [active]
1198114003922	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1198114003923	Zn binding site [ion binding]; other site
1198114003924	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1198114003925	Uncharacterized conserved protein [Function unknown]; Region: COG1543
1198114003926	N-terminal catalytic domain of Gh57 branching enzyme TK 1436 and similar proteins; Region: GH57N_BE_TK1436_like; cd10816
1198114003927	active site
1198114003928	substrate binding site [chemical binding]; other site
1198114003929	catalytic site [active]
1198114003930	Domain of unknown function (DUF1957); Region: DUF1957; pfam09210
1198114003931	BON domain; Region: BON; pfam04972
1198114003932	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1198114003933	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1198114003934	Ligand Binding Site [chemical binding]; other site
1198114003935	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1198114003936	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
1198114003937	hypothetical protein; Provisional; Region: PRK06489
1198114003938	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1198114003939	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
1198114003940	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
1198114003941	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1198114003942	protein binding site [polypeptide binding]; other site
1198114003943	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1198114003944	catalytic residues [active]
1198114003945	dimer interface [polypeptide binding]; other site
1198114003946	Amino acid permease; Region: AA_permease_2; pfam13520
1198114003947	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1198114003948	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114003949	Zn binding site [ion binding]; other site
1198114003950	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1198114003951	Zn binding site [ion binding]; other site
1198114003952	Glucose-6-phosphate dehydrogenase subunit; Region: OpcA_G6PD_assem; cl01359
1198114003953	Predicted esterase [General function prediction only]; Region: COG0400
1198114003954	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1198114003955	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1198114003956	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1198114003957	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1198114003958	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114003959	catalytic residue [active]
1198114003960	DinB superfamily; Region: DinB_2; pfam12867
1198114003961	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114003962	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1198114003963	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
1198114003964	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1198114003965	MarR family; Region: MarR_2; pfam12802
1198114003966	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1198114003967	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1198114003968	catalytic motif [active]
1198114003969	Zn binding site [ion binding]; other site
1198114003970	RibD C-terminal domain; Region: RibD_C; cl17279
1198114003971	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1198114003972	Lumazine binding domain; Region: Lum_binding; pfam00677
1198114003973	Lumazine binding domain; Region: Lum_binding; pfam00677
1198114003974	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1198114003975	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1198114003976	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1198114003977	RNA binding site [nucleotide binding]; other site
1198114003978	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1198114003979	multimer interface [polypeptide binding]; other site
1198114003980	Walker A motif; other site
1198114003981	ATP binding site [chemical binding]; other site
1198114003982	Walker B motif; other site
1198114003983	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
1198114003984	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114003985	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1198114003986	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114003987	Winged helix-turn helix; Region: HTH_29; pfam13551
1198114003988	Integrase core domain; Region: rve; pfam00665
1198114003989	Bacterial TniB protein; Region: TniB; pfam05621
1198114003990	AAA domain; Region: AAA_22; pfam13401
1198114003991	TniQ; Region: TniQ; pfam06527
1198114003992	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114003993	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1198114003994	catalytic residues [active]
1198114003995	catalytic nucleophile [active]
1198114003996	Presynaptic Site I dimer interface [polypeptide binding]; other site
1198114003997	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1198114003998	Synaptic Flat tetramer interface [polypeptide binding]; other site
1198114003999	Synaptic Site I dimer interface [polypeptide binding]; other site
1198114004000	DNA binding site [nucleotide binding]
1198114004001	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1198114004002	DNA-binding interface [nucleotide binding]; DNA binding site
1198114004003	Restriction endonuclease; Region: Mrr_cat; pfam04471
1198114004004	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114004005	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004006	TPR motif; other site
1198114004007	binding surface
1198114004008	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004009	binding surface
1198114004010	TPR repeat; Region: TPR_11; pfam13414
1198114004011	TPR motif; other site
1198114004012	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1198114004013	HNH endonuclease; Region: HNH_2; pfam13391
1198114004014	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1198114004015	active site
1198114004016	HNH endonuclease; Region: HNH_2; pfam13391
1198114004017	RepB plasmid partitioning protein; Region: RepB; pfam07506
1198114004018	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1198114004019	ParB-like nuclease domain; Region: ParBc; pfam02195
1198114004020	RepB plasmid partitioning protein; Region: RepB; pfam07506
1198114004021	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1198114004022	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1198114004023	catalytic residues [active]
1198114004024	catalytic nucleophile [active]
1198114004025	Recombinase; Region: Recombinase; pfam07508
1198114004026	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1198114004027	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1198114004028	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114004029	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1198114004030	Walker A motif; other site
1198114004031	ATP binding site [chemical binding]; other site
1198114004032	HEAT repeats; Region: HEAT_2; pfam13646
1198114004033	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1198114004034	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1198114004035	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1198114004036	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114004037	S-adenosylmethionine binding site [chemical binding]; other site
1198114004038	putative acyltransferase; Provisional; Region: PRK05790
1198114004039	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1198114004040	dimer interface [polypeptide binding]; other site
1198114004041	active site
1198114004042	CAAX protease self-immunity; Region: Abi; pfam02517
1198114004043	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1198114004044	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
1198114004045	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1198114004046	Bacillus subtilis (Bs) citrate synthase (CS)-II_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BSuCS-II_like; cd06110
1198114004047	dimer interface [polypeptide binding]; other site
1198114004048	Citrate synthase; Region: Citrate_synt; pfam00285
1198114004049	active site
1198114004050	citrylCoA binding site [chemical binding]; other site
1198114004051	oxalacetate/citrate binding site [chemical binding]; other site
1198114004052	coenzyme A binding site [chemical binding]; other site
1198114004053	catalytic triad [active]
1198114004054	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1198114004055	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114004056	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114004057	DNA binding residues [nucleotide binding]
1198114004058	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1198114004059	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1198114004060	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1198114004061	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114004062	putative active site [active]
1198114004063	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1198114004064	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1198114004065	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1198114004066	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1198114004067	competence damage-inducible protein A; Provisional; Region: PRK00549
1198114004068	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1198114004069	putative MPT binding site; other site
1198114004070	Competence-damaged protein; Region: CinA; pfam02464
1198114004071	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
1198114004072	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1198114004073	tetramer interfaces [polypeptide binding]; other site
1198114004074	binuclear metal-binding site [ion binding]; other site
1198114004075	Domain of unknown function (DUF329); Region: DUF329; pfam03884
1198114004076	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1198114004077	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1198114004078	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114004079	FeS/SAM binding site; other site
1198114004080	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1198114004081	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
1198114004082	proposed catalytic triad [active]
1198114004083	active site nucleophile [active]
1198114004084	glycogen synthase, Corynebacterium family; Region: glgA_Coryne; TIGR02149
1198114004085	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1198114004086	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1198114004087	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1198114004088	substrate binding pocket [chemical binding]; other site
1198114004089	chain length determination region; other site
1198114004090	substrate-Mg2+ binding site; other site
1198114004091	catalytic residues [active]
1198114004092	aspartate-rich region 1; other site
1198114004093	active site lid residues [active]
1198114004094	aspartate-rich region 2; other site
1198114004095	TGF-beta propeptide; Region: TGFb_propeptide; pfam00688
1198114004096	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1198114004097	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
1198114004098	putative binding surface; other site
1198114004099	active site
1198114004100	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114004101	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114004102	active site
1198114004103	phosphorylation site [posttranslational modification]
1198114004104	intermolecular recognition site; other site
1198114004105	dimerization interface [polypeptide binding]; other site
1198114004106	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114004107	phosphorylation site [posttranslational modification]
1198114004108	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114004109	ATP binding site [chemical binding]; other site
1198114004110	Mg2+ binding site [ion binding]; other site
1198114004111	G-X-G motif; other site
1198114004112	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114004113	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114004114	active site
1198114004115	phosphorylation site [posttranslational modification]
1198114004116	intermolecular recognition site; other site
1198114004117	dimerization interface [polypeptide binding]; other site
1198114004118	Deoxyhypusine synthase; Region: DS; cl00826
1198114004119	deoxyhypusine synthase; Region: dhys; TIGR00321
1198114004120	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114004121	non-specific DNA binding site [nucleotide binding]; other site
1198114004122	salt bridge; other site
1198114004123	sequence-specific DNA binding site [nucleotide binding]; other site
1198114004124	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
1198114004125	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1198114004126	active site
1198114004127	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cl16915
1198114004128	Zn binding site [ion binding]; other site
1198114004129	Uncharacterized protein conserved in bacteria (DUF2062); Region: DUF2062; cl01261
1198114004130	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1198114004131	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1198114004132	putative acyl-acceptor binding pocket; other site
1198114004133	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1198114004134	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1198114004135	ATP-binding site [chemical binding]; other site
1198114004136	Sugar specificity; other site
1198114004137	Pyrimidine base specificity; other site
1198114004138	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1198114004139	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1198114004140	dimer interface [polypeptide binding]; other site
1198114004141	FMN binding site [chemical binding]; other site
1198114004142	Ubiquitin-like proteins; Region: UBQ; cl00155
1198114004143	charged pocket; other site
1198114004144	hydrophobic patch; other site
1198114004145	Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltE; COG3967
1198114004146	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114004147	NAD(P) binding site [chemical binding]; other site
1198114004148	active site
1198114004149	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
1198114004150	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1198114004151	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1198114004152	Nucleoside recognition; Region: Gate; pfam07670
1198114004153	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1198114004154	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
1198114004155	putative heme binding pocket [chemical binding]; other site
1198114004156	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1198114004157	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114004158	NAD(P) binding site [chemical binding]; other site
1198114004159	active site
1198114004160	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1198114004161	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1198114004162	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1198114004163	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1198114004164	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1198114004165	active site
1198114004166	catalytic motif [active]
1198114004167	Zn binding site [ion binding]; other site
1198114004168	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1198114004169	putative binding surface; other site
1198114004170	active site
1198114004171	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1198114004172	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1198114004173	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114004174	ATP binding site [chemical binding]; other site
1198114004175	Mg2+ binding site [ion binding]; other site
1198114004176	G-X-G motif; other site
1198114004177	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1198114004178	CheW-like domain; Region: CheW; pfam01584
1198114004179	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114004180	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114004181	active site
1198114004182	phosphorylation site [posttranslational modification]
1198114004183	intermolecular recognition site; other site
1198114004184	dimerization interface [polypeptide binding]; other site
1198114004185	CheB methylesterase; Region: CheB_methylest; pfam01339
1198114004186	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1198114004187	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1198114004188	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114004189	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
1198114004190	ATP binding site [chemical binding]; other site
1198114004191	putative Mg++ binding site [ion binding]; other site
1198114004192	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114004193	nucleotide binding region [chemical binding]; other site
1198114004194	ATP-binding site [chemical binding]; other site
1198114004195	DEAD/H associated; Region: DEAD_assoc; pfam08494
1198114004196	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
1198114004197	formaldehyde dehydrogenase, glutathione-independent; Region: fdhA_non_GSH; TIGR02819
1198114004198	Pseudomonas putida aldehyde-dismutating formaldehyde dehydrogenase (PFDH); Region: PFDH_like; cd08282
1198114004199	NAD binding site [chemical binding]; other site
1198114004200	catalytic Zn binding site [ion binding]; other site
1198114004201	structural Zn binding site [ion binding]; other site
1198114004202	Isochorismatase family; Region: Isochorismatase; pfam00857
1198114004203	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1198114004204	catalytic triad [active]
1198114004205	conserved cis-peptide bond; other site
1198114004206	H+ Antiporter protein; Region: 2A0121; TIGR00900
1198114004207	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114004208	putative substrate translocation pore; other site
1198114004209	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1198114004210	MarR family; Region: MarR; pfam01047
1198114004211	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114004212	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114004213	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114004214	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114004215	active site
1198114004216	catalytic tetrad [active]
1198114004217	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1198114004218	homotrimer interaction site [polypeptide binding]; other site
1198114004219	zinc binding site [ion binding]; other site
1198114004220	CDP-binding sites; other site
1198114004221	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1198114004222	substrate binding site; other site
1198114004223	dimer interface; other site
1198114004224	Predicted integral membrane protein [Function unknown]; Region: COG5617
1198114004225	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
1198114004226	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1198114004227	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
1198114004228	active site
1198114004229	RibD C-terminal domain; Region: RibD_C; cl17279
1198114004230	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1198114004231	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1198114004232	RIP metalloprotease RseP; Region: TIGR00054
1198114004233	active site
1198114004234	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1198114004235	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1198114004236	protein binding site [polypeptide binding]; other site
1198114004237	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1198114004238	putative substrate binding region [chemical binding]; other site
1198114004239	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1198114004240	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1198114004241	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1198114004242	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1198114004243	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1198114004244	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1198114004245	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1198114004246	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114004247	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114004248	active site
1198114004249	catalytic tetrad [active]
1198114004250	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1198114004251	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1198114004252	catalytic residue [active]
1198114004253	putative FPP diphosphate  binding site; other site
1198114004254	putative FPP binding hydrophobic cleft; other site
1198114004255	dimer interface [polypeptide binding]; other site
1198114004256	putative IPP diphosphate binding site; other site
1198114004257	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1198114004258	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114004259	non-specific DNA binding site [nucleotide binding]; other site
1198114004260	salt bridge; other site
1198114004261	sequence-specific DNA binding site [nucleotide binding]; other site
1198114004262	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1198114004263	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1198114004264	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1198114004265	Isochorismatase family; Region: Isochorismatase; pfam00857
1198114004266	catalytic triad [active]
1198114004267	metal binding site [ion binding]; metal-binding site
1198114004268	conserved cis-peptide bond; other site
1198114004269	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1198114004270	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
1198114004271	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1198114004272	substrate binding [chemical binding]; other site
1198114004273	active site
1198114004274	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1198114004275	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1198114004276	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1198114004277	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1198114004278	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
1198114004279	active site
1198114004280	catalytic residues [active]
1198114004281	metal binding site [ion binding]; metal-binding site
1198114004282	enoyl-CoA hydratase; Provisional; Region: PRK05995
1198114004283	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1198114004284	substrate binding site [chemical binding]; other site
1198114004285	oxyanion hole (OAH) forming residues; other site
1198114004286	trimer interface [polypeptide binding]; other site
1198114004287	2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766
1198114004288	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1198114004289	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1198114004290	active site
1198114004291	HIGH motif; other site
1198114004292	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1198114004293	active site
1198114004294	KMSKS motif; other site
1198114004295	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1198114004296	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1198114004297	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114004298	catalytic residues [active]
1198114004299	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1198114004300	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1198114004301	putative active site [active]
1198114004302	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1198114004303	short chain dehydrogenase; Provisional; Region: PRK06914
1198114004304	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1198114004305	NADP binding site [chemical binding]; other site
1198114004306	active site
1198114004307	steroid binding site; other site
1198114004308	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114004309	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114004310	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
1198114004311	generic binding surface I; other site
1198114004312	generic binding surface II; other site
1198114004313	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1198114004314	Zn2+ binding site [ion binding]; other site
1198114004315	Mg2+ binding site [ion binding]; other site
1198114004316	SurA N-terminal domain; Region: SurA_N; pfam09312
1198114004317	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1198114004318	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1198114004319	C-terminal peptidase (prc); Region: prc; TIGR00225
1198114004320	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1198114004321	protein binding site [polypeptide binding]; other site
1198114004322	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1198114004323	Catalytic dyad [active]
1198114004324	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114004325	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114004326	Ubiquitin-like proteins; Region: UBQ; cl00155
1198114004327	charged pocket; other site
1198114004328	hydrophobic patch; other site
1198114004329	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114004330	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114004331	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1198114004332	active site
1198114004333	metal binding site [ion binding]; metal-binding site
1198114004334	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1198114004335	Catalytic domain of Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1-like proteins; Region: PI-PLCc_SaPLC1_like; cd08589
1198114004336	putative active site [active]
1198114004337	catalytic site [active]
1198114004338	putative metal binding site [ion binding]; other site
1198114004339	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114004340	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1198114004341	metal binding site [ion binding]; metal-binding site
1198114004342	active site
1198114004343	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
1198114004344	N-terminal domain of the actinomycetal Nei2 and related DNA glycosylases; Region: AcNei2_N; cd08971
1198114004345	putative DNA binding site [nucleotide binding]; other site
1198114004346	catalytic residue [active]
1198114004347	putative H2TH interface [polypeptide binding]; other site
1198114004348	putative catalytic residues [active]
1198114004349	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1198114004350	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1198114004351	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1198114004352	Transglycosylase; Region: Transgly; pfam00912
1198114004353	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1198114004354	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1198114004355	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1198114004356	dimer interface [polypeptide binding]; other site
1198114004357	motif 1; other site
1198114004358	active site
1198114004359	motif 2; other site
1198114004360	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1198114004361	putative deacylase active site [active]
1198114004362	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1198114004363	active site
1198114004364	motif 3; other site
1198114004365	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1198114004366	anticodon binding site; other site
1198114004367	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114004368	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1198114004369	ligand binding site [chemical binding]; other site
1198114004370	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1198114004371	putative switch regulator; other site
1198114004372	non-specific DNA interactions [nucleotide binding]; other site
1198114004373	DNA binding site [nucleotide binding]
1198114004374	sequence specific DNA binding site [nucleotide binding]; other site
1198114004375	putative cAMP binding site [chemical binding]; other site
1198114004376	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1198114004377	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1198114004378	Tetramer interface [polypeptide binding]; other site
1198114004379	active site
1198114004380	FMN-binding site [chemical binding]; other site
1198114004381	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1198114004382	active site
1198114004383	catalytic residues [active]
1198114004384	metal binding site [ion binding]; metal-binding site
1198114004385	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1198114004386	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1198114004387	putative active site [active]
1198114004388	substrate binding site [chemical binding]; other site
1198114004389	putative cosubstrate binding site; other site
1198114004390	catalytic site [active]
1198114004391	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1198114004392	substrate binding site [chemical binding]; other site
1198114004393	NusB family; Region: NusB; pfam01029
1198114004394	putative RNA binding site [nucleotide binding]; other site
1198114004395	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1198114004396	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114004397	S-adenosylmethionine binding site [chemical binding]; other site
1198114004398	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1198114004399	PASTA domain; Region: PASTA; smart00740
1198114004400	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1198114004401	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1198114004402	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114004403	non-specific DNA binding site [nucleotide binding]; other site
1198114004404	salt bridge; other site
1198114004405	sequence-specific DNA binding site [nucleotide binding]; other site
1198114004406	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1198114004407	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
1198114004408	L-aspartate oxidase; Provisional; Region: PRK06175
1198114004409	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
1198114004410	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1198114004411	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114004412	PA_M28_2: Protease-associated (PA) domain, peptidase family M28, subfamily-2. A subfamily of PA-domain containing proteins belonging to the peptidase family M28. Family M28 contains aminopeptidases and carboxypeptidases, and has co-catalytic zinc ions; Region: PA_M28_2; cd04815
1198114004413	PA/protease or protease-like domain interface [polypeptide binding]; other site
1198114004414	M28 Zn-Peptidase Plasma glutamate carboxypeptidase; Region: M28_Pgcp_like; cd03883
1198114004415	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114004416	metal binding site [ion binding]; metal-binding site
1198114004417	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1198114004418	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
1198114004419	active site
1198114004420	dimer interface [polypeptide binding]; other site
1198114004421	metal binding site [ion binding]; metal-binding site
1198114004422	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1198114004423	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114004424	S-adenosylmethionine binding site [chemical binding]; other site
1198114004425	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1198114004426	Cation efflux family; Region: Cation_efflux; pfam01545
1198114004427	Cation efflux family; Region: Cation_efflux; cl00316
1198114004428	Cation efflux family; Region: Cation_efflux; cl00316
1198114004429	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1198114004430	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1198114004431	inhibitor-cofactor binding pocket; inhibition site
1198114004432	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114004433	catalytic residue [active]
1198114004434	bacterial Hfq-like; Region: Hfq; cd01716
1198114004435	hexamer interface [polypeptide binding]; other site
1198114004436	Sm1 motif; other site
1198114004437	RNA binding site [nucleotide binding]; other site
1198114004438	Sm2 motif; other site
1198114004439	F0F1 ATP synthase subunit B'; Validated; Region: PRK07353
1198114004440	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
1198114004441	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1198114004442	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
1198114004443	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
1198114004444	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1198114004445	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1198114004446	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1198114004447	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1198114004448	beta subunit interaction interface [polypeptide binding]; other site
1198114004449	Walker A motif; other site
1198114004450	ATP binding site [chemical binding]; other site
1198114004451	Walker B motif; other site
1198114004452	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1198114004453	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1198114004454	core domain interface [polypeptide binding]; other site
1198114004455	delta subunit interface [polypeptide binding]; other site
1198114004456	epsilon subunit interface [polypeptide binding]; other site
1198114004457	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1198114004458	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1198114004459	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1198114004460	alpha subunit interaction interface [polypeptide binding]; other site
1198114004461	Walker A motif; other site
1198114004462	ATP binding site [chemical binding]; other site
1198114004463	Walker B motif; other site
1198114004464	inhibitor binding site; inhibition site
1198114004465	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1198114004466	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1198114004467	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1198114004468	gamma subunit interface [polypeptide binding]; other site
1198114004469	epsilon subunit interface [polypeptide binding]; other site
1198114004470	LBP interface [polypeptide binding]; other site
1198114004471	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1198114004472	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1198114004473	FMN binding site [chemical binding]; other site
1198114004474	active site
1198114004475	substrate binding site [chemical binding]; other site
1198114004476	catalytic residue [active]
1198114004477	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114004478	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114004479	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114004480	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114004481	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114004482	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1198114004483	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1198114004484	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1198114004485	Walker A/P-loop; other site
1198114004486	ATP binding site [chemical binding]; other site
1198114004487	Q-loop/lid; other site
1198114004488	ABC transporter signature motif; other site
1198114004489	Walker B; other site
1198114004490	D-loop; other site
1198114004491	H-loop/switch region; other site
1198114004492	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1198114004493	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1198114004494	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1198114004495	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1198114004496	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1198114004497	30S subunit binding site; other site
1198114004498	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
1198114004499	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1198114004500	active site
1198114004501	HIGH motif; other site
1198114004502	KMSKS motif; other site
1198114004503	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1198114004504	tRNA binding surface [nucleotide binding]; other site
1198114004505	anticodon binding site; other site
1198114004506	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1198114004507	dimer interface [polypeptide binding]; other site
1198114004508	putative tRNA-binding site [nucleotide binding]; other site
1198114004509	transcriptional regulator NanR; Provisional; Region: PRK03837
1198114004510	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1198114004511	DNA-binding site [nucleotide binding]; DNA binding site
1198114004512	FCD domain; Region: FCD; pfam07729
1198114004513	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114004514	putative substrate translocation pore; other site
1198114004515	putative pectinesterase; Region: PLN02432; cl01911
1198114004516	Pectinesterase; Region: Pectinesterase; pfam01095
1198114004517	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114004518	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
1198114004519	dimer interface [polypeptide binding]; other site
1198114004520	substrate binding site [chemical binding]; other site
1198114004521	metal binding site [ion binding]; metal-binding site
1198114004522	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1198114004523	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1198114004524	Coenzyme A binding pocket [chemical binding]; other site
1198114004525	Protein of unknown function (DUF3738); Region: DUF3738; cl11887
1198114004526	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
1198114004527	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1198114004528	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1198114004529	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
1198114004530	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1198114004531	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1198114004532	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114004533	NAD(P) binding site [chemical binding]; other site
1198114004534	active site
1198114004535	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1198114004536	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1198114004537	FMN binding site [chemical binding]; other site
1198114004538	active site
1198114004539	substrate binding site [chemical binding]; other site
1198114004540	catalytic residue [active]
1198114004541	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
1198114004542	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
1198114004543	putative metal binding site [ion binding]; other site
1198114004544	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1198114004545	active site
1198114004546	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114004547	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114004548	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
1198114004549	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1198114004550	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1198114004551	active site
1198114004552	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1198114004553	Catalytic NodB homology domain of uncharacterized bacterial glycosyl transferase, group 2-like family proteins; Region: CE4_GT2-like; cd10962
1198114004554	NodB motif; other site
1198114004555	putative active site [active]
1198114004556	putative catalytic site [active]
1198114004557	putative Zn binding site [ion binding]; other site
1198114004558	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1198114004559	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1198114004560	DXD motif; other site
1198114004561	Delta(1)-pyrroline-5-carboxylate dehydrogenase, RocA; Region: ALDH_PutA-P5CDH-RocA; cd07124
1198114004562	1-pyrroline-5-carboxylate dehydrogenase; Provisional; Region: PRK03137
1198114004563	Glutamate binding site [chemical binding]; other site
1198114004564	homodimer interface [polypeptide binding]; other site
1198114004565	NAD binding site [chemical binding]; other site
1198114004566	catalytic residues [active]
1198114004567	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114004568	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114004569	DNA binding residues [nucleotide binding]
1198114004570	dimerization interface [polypeptide binding]; other site
1198114004571	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114004572	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114004573	active site
1198114004574	phosphorylation site [posttranslational modification]
1198114004575	intermolecular recognition site; other site
1198114004576	dimerization interface [polypeptide binding]; other site
1198114004577	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1198114004578	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1198114004579	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1198114004580	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114004581	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114004582	ligand binding site [chemical binding]; other site
1198114004583	flexible hinge region; other site
1198114004584	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114004585	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114004586	ATP binding site [chemical binding]; other site
1198114004587	Mg2+ binding site [ion binding]; other site
1198114004588	G-X-G motif; other site
1198114004589	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_18; cd08357
1198114004590	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114004591	putative metal binding site [ion binding]; other site
1198114004592	NHL repeat; Region: NHL; pfam01436
1198114004593	NHL repeat; Region: NHL; pfam01436
1198114004594	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1198114004595	seryl-tRNA synthetase; Provisional; Region: PRK05431
1198114004596	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1198114004597	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1198114004598	dimer interface [polypeptide binding]; other site
1198114004599	active site
1198114004600	motif 1; other site
1198114004601	motif 2; other site
1198114004602	motif 3; other site
1198114004603	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1198114004604	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1198114004605	heterodimer interface [polypeptide binding]; other site
1198114004606	active site
1198114004607	FMN binding site [chemical binding]; other site
1198114004608	homodimer interface [polypeptide binding]; other site
1198114004609	substrate binding site [chemical binding]; other site
1198114004610	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1198114004611	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1198114004612	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1198114004613	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1198114004614	RNA binding site [nucleotide binding]; other site
1198114004615	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1198114004616	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1198114004617	purine monophosphate binding site [chemical binding]; other site
1198114004618	dimer interface [polypeptide binding]; other site
1198114004619	putative catalytic residues [active]
1198114004620	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1198114004621	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1198114004622	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004623	binding surface
1198114004624	TPR motif; other site
1198114004625	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004626	TPR motif; other site
1198114004627	binding surface
1198114004628	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004629	TPR motif; other site
1198114004630	binding surface
1198114004631	TPR repeat; Region: TPR_11; pfam13414
1198114004632	TPR repeat; Region: TPR_11; pfam13414
1198114004633	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004634	binding surface
1198114004635	TPR motif; other site
1198114004636	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
1198114004637	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1198114004638	Zn2+ binding site [ion binding]; other site
1198114004639	Mg2+ binding site [ion binding]; other site
1198114004640	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1198114004641	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004642	binding surface
1198114004643	TPR motif; other site
1198114004644	TPR repeat; Region: TPR_11; pfam13414
1198114004645	TPR repeat; Region: TPR_11; pfam13414
1198114004646	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004647	TPR motif; other site
1198114004648	binding surface
1198114004649	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1198114004650	4-alpha-glucanotransferase; Provisional; Region: PRK14508
1198114004651	SurA N-terminal domain; Region: SurA_N_3; cl07813
1198114004652	periplasmic folding chaperone; Provisional; Region: PRK10788
1198114004653	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1198114004654	BON domain; Region: BON; pfam04972
1198114004655	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1198114004656	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1198114004657	DNA binding site [nucleotide binding]
1198114004658	domain linker motif; other site
1198114004659	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1198114004660	dimerization interface [polypeptide binding]; other site
1198114004661	ligand binding site [chemical binding]; other site
1198114004662	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1198114004663	Sulfatase; Region: Sulfatase; pfam00884
1198114004664	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114004665	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1198114004666	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114004667	DinB superfamily; Region: DinB_2; pfam12867
1198114004668	Helix-turn-helix domain; Region: HTH_20; pfam12840
1198114004669	dimerization interface [polypeptide binding]; other site
1198114004670	putative DNA binding site [nucleotide binding]; other site
1198114004671	putative Zn2+ binding site [ion binding]; other site
1198114004672	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114004673	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114004674	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1198114004675	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases [Carbohydrate transport and metabolism]; Region: AraD; COG0235
1198114004676	intersubunit interface [polypeptide binding]; other site
1198114004677	active site
1198114004678	Zn2+ binding site [ion binding]; other site
1198114004679	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114004680	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1198114004681	FeS/SAM binding site; other site
1198114004682	ribulokinase; Provisional; Region: PRK04123
1198114004683	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1198114004684	N- and C-terminal domain interface [polypeptide binding]; other site
1198114004685	active site
1198114004686	MgATP binding site [chemical binding]; other site
1198114004687	catalytic site [active]
1198114004688	metal binding site [ion binding]; metal-binding site
1198114004689	carbohydrate binding site [chemical binding]; other site
1198114004690	homodimer interface [polypeptide binding]; other site
1198114004691	L-arabinose isomerase; Provisional; Region: PRK02929
1198114004692	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1198114004693	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1198114004694	trimer interface [polypeptide binding]; other site
1198114004695	putative substrate binding site [chemical binding]; other site
1198114004696	putative metal binding site [ion binding]; other site
1198114004697	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
1198114004698	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1198114004699	intersubunit interface [polypeptide binding]; other site
1198114004700	active site
1198114004701	Zn2+ binding site [ion binding]; other site
1198114004702	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1198114004703	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114004704	motif II; other site
1198114004705	TOBE domain; Region: TOBE; cl01440
1198114004706	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114004707	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
1198114004708	DNA binding residues [nucleotide binding]
1198114004709	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1198114004710	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1198114004711	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1198114004712	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1198114004713	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1198114004714	oxidoreductase; Provisional; Region: PRK06128
1198114004715	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114004716	NAD(P) binding site [chemical binding]; other site
1198114004717	active site
1198114004718	Sm and related proteins; Region: Sm_like; cd00600
1198114004719	Sm1 motif; other site
1198114004720	hexamer interface [polypeptide binding]; other site
1198114004721	heptamer interface [polypeptide binding]; other site
1198114004722	RNA binding site [nucleotide binding]; other site
1198114004723	Sm2 motif; other site
1198114004724	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1198114004725	protein binding site [polypeptide binding]; other site
1198114004726	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1198114004727	protein binding site [polypeptide binding]; other site
1198114004728	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1198114004729	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1198114004730	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114004731	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1198114004732	FtsX-like permease family; Region: FtsX; pfam02687
1198114004733	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114004734	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1198114004735	FtsX-like permease family; Region: FtsX; pfam02687
1198114004736	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1198114004737	Zn binding site [ion binding]; other site
1198114004738	TPR repeat; Region: TPR_11; pfam13414
1198114004739	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114004740	TPR motif; other site
1198114004741	binding surface
1198114004742	Domain of unknown function (DUF4126); Region: DUF4126; pfam13548
1198114004743	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114004744	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114004745	active site
1198114004746	phosphorylation site [posttranslational modification]
1198114004747	intermolecular recognition site; other site
1198114004748	dimerization interface [polypeptide binding]; other site
1198114004749	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114004750	DNA binding site [nucleotide binding]
1198114004751	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
1198114004752	putative active site [active]
1198114004753	MarC family integral membrane protein; Region: MarC; cl00919
1198114004754	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114004755	dimer interface [polypeptide binding]; other site
1198114004756	phosphorylation site [posttranslational modification]
1198114004757	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114004758	ATP binding site [chemical binding]; other site
1198114004759	Mg2+ binding site [ion binding]; other site
1198114004760	G-X-G motif; other site
1198114004761	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1198114004762	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1198114004763	substrate binding pocket [chemical binding]; other site
1198114004764	catalytic triad [active]
1198114004765	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1198114004766	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1198114004767	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1198114004768	ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CcmB; COG2386
1198114004769	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1198114004770	putative deacylase active site [active]
1198114004771	CcmE; Region: CcmE; cl00994
1198114004772	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1198114004773	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1198114004774	Walker A/P-loop; other site
1198114004775	ATP binding site [chemical binding]; other site
1198114004776	Q-loop/lid; other site
1198114004777	ABC transporter signature motif; other site
1198114004778	Walker B; other site
1198114004779	D-loop; other site
1198114004780	H-loop/switch region; other site
1198114004781	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1198114004782	metal binding triad [ion binding]; metal-binding site
1198114004783	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1198114004784	Thioredoxin; Region: Thioredoxin_4; pfam13462
1198114004785	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
1198114004786	ThiC family; Region: ThiC; pfam01964
1198114004787	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114004788	PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; Region: PA_GCPII_like; cd02121
1198114004789	apical/protease domain interface [polypeptide binding]; other site
1198114004790	substrate binding [chemical binding]; other site
1198114004791	dimer interface [polypeptide binding]; other site
1198114004792	M28 Zn-peptidase prostate-specific membrane antigen; Region: M28_PSMA_like; cd08022
1198114004793	dimer interface [polypeptide binding]; other site
1198114004794	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114004795	active site
1198114004796	metal binding site [ion binding]; metal-binding site
1198114004797	Transferrin receptor-like dimerisation domain; Region: TFR_dimer; pfam04253
1198114004798	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1198114004799	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
1198114004800	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114004801	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1198114004802	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182; cl00348
1198114004803	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1198114004804	Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504
1198114004805	SnoaL-like domain; Region: SnoaL_3; pfam13474
1198114004806	Helix-turn-helix domain; Region: HTH_18; pfam12833
1198114004807	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114004808	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1198114004809	active site
1198114004810	CAAX protease self-immunity; Region: Abi; pfam02517
1198114004811	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1198114004812	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114004813	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114004814	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1198114004815	MerC mercury resistance protein; Region: MerC; pfam03203
1198114004816	Putative zinc-finger; Region: zf-HC2; pfam13490
1198114004817	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1198114004818	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114004819	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114004820	DNA binding residues [nucleotide binding]
1198114004821	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
1198114004822	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114004823	Mg-chelatase subunit ChlI [Coenzyme metabolism]; Region: ChlI; COG1239
1198114004824	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1198114004825	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1198114004826	TPR motif; other site
1198114004827	TPR repeat; Region: TPR_11; pfam13414
1198114004828	binding surface
1198114004829	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1198114004830	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1198114004831	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1198114004832	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
1198114004833	GrpE; Region: GrpE; pfam01025
1198114004834	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1198114004835	dimer interface [polypeptide binding]; other site
1198114004836	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1198114004837	chaperone protein DnaJ; Provisional; Region: PRK10767
1198114004838	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1198114004839	HSP70 interaction site [polypeptide binding]; other site
1198114004840	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1198114004841	substrate binding site [polypeptide binding]; other site
1198114004842	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1198114004843	Zn binding sites [ion binding]; other site
1198114004844	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1198114004845	dimer interface [polypeptide binding]; other site
1198114004846	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1198114004847	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1198114004848	shikimate kinase; Reviewed; Region: aroK; PRK00131
1198114004849	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1198114004850	ADP binding site [chemical binding]; other site
1198114004851	magnesium binding site [ion binding]; other site
1198114004852	putative shikimate binding site; other site
1198114004853	Protein of unknown function (DUF1223); Region: DUF1223; pfam06764
1198114004854	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1198114004855	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1198114004856	ABC transporter; Region: ABC_tran_2; pfam12848
1198114004857	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1198114004858	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1198114004859	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114004860	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
1198114004861	active site
1198114004862	DinB family; Region: DinB; cl17821
1198114004863	DinB superfamily; Region: DinB_2; pfam12867
1198114004864	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
1198114004865	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1198114004866	NAD binding site [chemical binding]; other site
1198114004867	homotetramer interface [polypeptide binding]; other site
1198114004868	homodimer interface [polypeptide binding]; other site
1198114004869	substrate binding site [chemical binding]; other site
1198114004870	active site
1198114004871	EVE domain; Region: EVE; pfam01878
1198114004872	glutamate racemase; Provisional; Region: PRK00865
1198114004873	Sporulation and spore germination; Region: Germane; pfam10646
1198114004874	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1198114004875	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1198114004876	active site
1198114004877	metal binding site [ion binding]; metal-binding site
1198114004878	Uncharacterized conserved protein [Function unknown]; Region: COG4198
1198114004879	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
1198114004880	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1198114004881	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114004882	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114004883	metal ion-dependent adhesion site (MIDAS); other site
1198114004884	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114004885	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114004886	metal ion-dependent adhesion site (MIDAS); other site
1198114004887	Protein of unknown function (DUF3380); Region: DUF3380; pfam11860
1198114004888	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1198114004889	ATP-dependent helicase HrpB; Region: DEAH_box_HrpB; TIGR01970
1198114004890	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114004891	ATP binding site [chemical binding]; other site
1198114004892	putative Mg++ binding site [ion binding]; other site
1198114004893	nucleotide binding region [chemical binding]; other site
1198114004894	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1198114004895	Helicase associated domain (HA2); Region: HA2; pfam04408
1198114004896	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1198114004897	2-hydroxycyclohexanecarboxyl-CoA dehydrogenase; Region: benzo_BadH; TIGR03206
1198114004898	Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs; Region: carb_red_PTCR-like_SDR_c; cd05324
1198114004899	NADP binding site [chemical binding]; other site
1198114004900	substrate binding site [chemical binding]; other site
1198114004901	active site
1198114004902	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
1198114004903	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1198114004904	Ligand binding site; other site
1198114004905	Putative Catalytic site; other site
1198114004906	DXD motif; other site
1198114004907	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1198114004908	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114004909	Coenzyme A binding pocket [chemical binding]; other site
1198114004910	GTP-binding protein YchF; Reviewed; Region: PRK09601
1198114004911	YchF GTPase; Region: YchF; cd01900
1198114004912	G1 box; other site
1198114004913	GTP/Mg2+ binding site [chemical binding]; other site
1198114004914	Switch I region; other site
1198114004915	G2 box; other site
1198114004916	Switch II region; other site
1198114004917	G3 box; other site
1198114004918	G4 box; other site
1198114004919	G5 box; other site
1198114004920	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1198114004921	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
1198114004922	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1198114004923	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1198114004924	NADP binding site [chemical binding]; other site
1198114004925	dimer interface [polypeptide binding]; other site
1198114004926	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114004927	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114004928	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114004929	Cupin domain; Region: Cupin_2; pfam07883
1198114004930	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1198114004931	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114004932	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114004933	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114004934	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114004935	short chain dehydrogenase; Provisional; Region: PRK06924
1198114004936	NAD(P) binding site [chemical binding]; other site
1198114004937	active site
1198114004938	oxidoreductase; Provisional; Region: PRK06196
1198114004939	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
1198114004940	putative NAD(P) binding site [chemical binding]; other site
1198114004941	active site
1198114004942	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114004943	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114004944	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1198114004945	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1198114004946	ring oligomerisation interface [polypeptide binding]; other site
1198114004947	ATP/Mg binding site [chemical binding]; other site
1198114004948	stacking interactions; other site
1198114004949	hinge regions; other site
1198114004950	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1198114004951	oligomerisation interface [polypeptide binding]; other site
1198114004952	mobile loop; other site
1198114004953	roof hairpin; other site
1198114004954	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1198114004955	pteridine reductase; Provisional; Region: PRK09135
1198114004956	classical (c) SDRs; Region: SDR_c; cd05233
1198114004957	NAD(P) binding site [chemical binding]; other site
1198114004958	active site
1198114004959	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
1198114004960	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
1198114004961	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1198114004962	putative active site [active]
1198114004963	catalytic triad [active]
1198114004964	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1198114004965	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1198114004966	active site
1198114004967	catalytic site [active]
1198114004968	Domain of unknown function (DUF1939); Region: DUF1939; pfam09154
1198114004969	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114004970	DNA-binding site [nucleotide binding]; DNA binding site
1198114004971	RNA-binding motif; other site
1198114004972	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114004973	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114004974	active site
1198114004975	phosphorylation site [posttranslational modification]
1198114004976	intermolecular recognition site; other site
1198114004977	dimerization interface [polypeptide binding]; other site
1198114004978	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114004979	DNA binding residues [nucleotide binding]
1198114004980	dimerization interface [polypeptide binding]; other site
1198114004981	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
1198114004982	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114004983	dimer interface [polypeptide binding]; other site
1198114004984	conserved gate region; other site
1198114004985	putative PBP binding loops; other site
1198114004986	ABC-ATPase subunit interface; other site
1198114004987	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114004988	dimer interface [polypeptide binding]; other site
1198114004989	ABC-ATPase subunit interface; other site
1198114004990	putative PBP binding loops; other site
1198114004991	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1198114004992	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1198114004993	Walker A/P-loop; other site
1198114004994	ATP binding site [chemical binding]; other site
1198114004995	Q-loop/lid; other site
1198114004996	ABC transporter signature motif; other site
1198114004997	Walker B; other site
1198114004998	D-loop; other site
1198114004999	H-loop/switch region; other site
1198114005000	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
1198114005001	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114005002	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114005003	active site
1198114005004	phosphorylation site [posttranslational modification]
1198114005005	intermolecular recognition site; other site
1198114005006	dimerization interface [polypeptide binding]; other site
1198114005007	putative acyl transferase; Provisional; Region: PRK10502
1198114005008	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1198114005009	putative trimer interface [polypeptide binding]; other site
1198114005010	putative active site [active]
1198114005011	putative substrate binding site [chemical binding]; other site
1198114005012	putative CoA binding site [chemical binding]; other site
1198114005013	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114005014	This family is most closely related to the GT1 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide; Region: GT1_Bme6_like; cd03821
1198114005015	putative ADP-binding pocket [chemical binding]; other site
1198114005016	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114005017	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1198114005018	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1198114005019	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
1198114005020	exopolysaccharide transport protein family; Region: eps_transp_fam; TIGR01005
1198114005021	Chain length determinant protein; Region: Wzz; pfam02706
1198114005022	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1198114005023	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1198114005024	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1198114005025	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1198114005026	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1198114005027	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1198114005028	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
1198114005029	NAD binding site [chemical binding]; other site
1198114005030	putative substrate binding site 2 [chemical binding]; other site
1198114005031	putative substrate binding site 1 [chemical binding]; other site
1198114005032	active site
1198114005033	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
1198114005034	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1198114005035	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
1198114005036	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1198114005037	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1198114005038	dimer interface [polypeptide binding]; other site
1198114005039	TPP-binding site [chemical binding]; other site
1198114005040	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1198114005041	heterotetramer interface [polypeptide binding]; other site
1198114005042	active site pocket [active]
1198114005043	cleavage site
1198114005044	putative oxidoreductase; Provisional; Region: PRK11579
1198114005045	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114005046	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1198114005047	Outer membrane efflux protein; Region: OEP; pfam02321
1198114005048	Outer membrane efflux protein; Region: OEP; pfam02321
1198114005049	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1198114005050	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114005051	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114005052	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1198114005053	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1198114005054	dimerization interface [polypeptide binding]; other site
1198114005055	DPS ferroxidase diiron center [ion binding]; other site
1198114005056	ion pore; other site
1198114005057	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1198114005058	Flavoprotein; Region: Flavoprotein; pfam02441
1198114005059	adenylosuccinate lyase; Provisional; Region: PRK07492
1198114005060	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1198114005061	tetramer interface [polypeptide binding]; other site
1198114005062	active site
1198114005063	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1198114005064	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1198114005065	catalytic residues [active]
1198114005066	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1198114005067	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114005068	NAD(P) binding site [chemical binding]; other site
1198114005069	active site
1198114005070	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1198114005071	nucleoside/Zn binding site; other site
1198114005072	dimer interface [polypeptide binding]; other site
1198114005073	catalytic motif [active]
1198114005074	Protein of unknown function (DUF3175); Region: DUF3175; pfam11373
1198114005075	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
1198114005076	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1198114005077	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114005078	peptidase domain interface [polypeptide binding]; other site
1198114005079	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114005080	active site
1198114005081	catalytic triad [active]
1198114005082	calcium binding site [ion binding]; other site
1198114005083	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
1198114005084	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114005085	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1198114005086	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114005087	choice-of-anchor B domain; Region: choice_anch_B; TIGR04312
1198114005088	Domain of unknown function (DUF305); Region: DUF305; pfam03713
1198114005089	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1198114005090	MarR family; Region: MarR_2; cl17246
1198114005091	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1198114005092	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1198114005093	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
1198114005094	putative active site; other site
1198114005095	catalytic triad [active]
1198114005096	putative dimer interface [polypeptide binding]; other site
1198114005097	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1198114005098	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1198114005099	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1198114005100	malate dehydrogenase; Reviewed; Region: PRK06223
1198114005101	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1198114005102	NAD(P) binding site [chemical binding]; other site
1198114005103	dimer interface [polypeptide binding]; other site
1198114005104	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1198114005105	substrate binding site [chemical binding]; other site
1198114005106	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1198114005107	active site
1198114005108	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1198114005109	active site
1198114005110	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
1198114005111	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1198114005112	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1198114005113	active site
1198114005114	dimer interface [polypeptide binding]; other site
1198114005115	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1198114005116	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1198114005117	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
1198114005118	active site
1198114005119	metal binding site [ion binding]; metal-binding site
1198114005120	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1198114005121	active site
1198114005122	metal binding site [ion binding]; metal-binding site
1198114005123	YcfA-like protein; Region: YcfA; cl00752
1198114005124	Uncharacterized protein family (UPF0150); Region: UPF0150; cl00691
1198114005125	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK08640
1198114005126	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1198114005127	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08641
1198114005128	L-aspartate oxidase; Provisional; Region: PRK06175
1198114005129	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1198114005130	Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis...; Region: SQR_TypeB_1_TM; cd03497
1198114005131	putative Iron-sulfur protein interface [polypeptide binding]; other site
1198114005132	proximal heme binding site [chemical binding]; other site
1198114005133	distal heme binding site [chemical binding]; other site
1198114005134	putative dimer interface [polypeptide binding]; other site
1198114005135	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1198114005136	active site
1198114005137	dimerization interface [polypeptide binding]; other site
1198114005138	Domain of unknown function (DUF4375); Region: DUF4375; pfam14300
1198114005139	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1198114005140	flagellar motor protein MotB; Reviewed; Region: motB; PRK07734
1198114005141	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1198114005142	ligand binding site [chemical binding]; other site
1198114005143	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1198114005144	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1198114005145	Flagellar protein (FlbD); Region: FlbD; pfam06289
1198114005146	Flagellin and related hook-associated proteins [Cell motility and secretion]; Region: FlgL; COG1344
1198114005147	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1198114005148	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1198114005149	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1198114005150	Flagellar protein FliS; Region: FliS; cl00654
1198114005151	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1198114005152	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1198114005153	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114005154	Walker A/P-loop; other site
1198114005155	ATP binding site [chemical binding]; other site
1198114005156	Q-loop/lid; other site
1198114005157	ABC transporter signature motif; other site
1198114005158	Walker B; other site
1198114005159	D-loop; other site
1198114005160	H-loop/switch region; other site
1198114005161	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1198114005162	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
1198114005163	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1198114005164	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1198114005165	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
1198114005166	4Fe-4S binding domain; Region: Fer4; pfam00037
1198114005167	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1198114005168	Zn2+ binding site [ion binding]; other site
1198114005169	Mg2+ binding site [ion binding]; other site
1198114005170	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1198114005171	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1198114005172	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
1198114005173	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1198114005174	substrate binding pocket [chemical binding]; other site
1198114005175	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1198114005176	B12 binding site [chemical binding]; other site
1198114005177	cobalt ligand [ion binding]; other site
1198114005178	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1198114005179	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1198114005180	phosphorylation site [posttranslational modification]
1198114005181	threonine synthase; Validated; Region: PRK07591
1198114005182	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
1198114005183	homodimer interface [polypeptide binding]; other site
1198114005184	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114005185	catalytic residue [active]
1198114005186	ThiS family; Region: ThiS; pfam02597
1198114005187	charged pocket; other site
1198114005188	hydrophobic patch; other site
1198114005189	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1198114005190	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1198114005191	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114005192	Walker A motif; other site
1198114005193	ATP binding site [chemical binding]; other site
1198114005194	Walker B motif; other site
1198114005195	arginine finger; other site
1198114005196	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1198114005197	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1198114005198	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1198114005199	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114005200	Walker A motif; other site
1198114005201	ATP binding site [chemical binding]; other site
1198114005202	Walker B motif; other site
1198114005203	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1198114005204	Clp protease; Region: CLP_protease; pfam00574
1198114005205	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1198114005206	oligomer interface [polypeptide binding]; other site
1198114005207	active site residues [active]
1198114005208	trigger factor; Region: tig; TIGR00115
1198114005209	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1198114005210	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1198114005211	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
1198114005212	active site
1198114005213	catalytic residues [active]
1198114005214	Family-5 Uracil-DNA glycosylases (UDG), found in thermophilic organisms; Region: UDG_F5_TTUDGB_like; cd10031
1198114005215	Fe-S cluster binding site [ion binding]; other site
1198114005216	DNA binding site [nucleotide binding]
1198114005217	active site
1198114005218	YtxH-like protein; Region: YtxH; pfam12732
1198114005219	Cupin domain; Region: Cupin_2; pfam07883
1198114005220	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1198114005221	Clp amino terminal domain; Region: Clp_N; pfam02861
1198114005222	Clp amino terminal domain; Region: Clp_N; pfam02861
1198114005223	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114005224	Walker A motif; other site
1198114005225	ATP binding site [chemical binding]; other site
1198114005226	Walker B motif; other site
1198114005227	arginine finger; other site
1198114005228	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114005229	Walker A motif; other site
1198114005230	ATP binding site [chemical binding]; other site
1198114005231	Walker B motif; other site
1198114005232	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1198114005233	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114005234	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114005235	Walker A/P-loop; other site
1198114005236	ATP binding site [chemical binding]; other site
1198114005237	Q-loop/lid; other site
1198114005238	ABC transporter signature motif; other site
1198114005239	Walker B; other site
1198114005240	D-loop; other site
1198114005241	H-loop/switch region; other site
1198114005242	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1198114005243	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1198114005244	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1198114005245	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114005246	FtsX-like permease family; Region: FtsX; pfam02687
1198114005247	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1198114005248	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1198114005249	putative NAD(P) binding site [chemical binding]; other site
1198114005250	putative substrate binding site [chemical binding]; other site
1198114005251	catalytic Zn binding site [ion binding]; other site
1198114005252	structural Zn binding site [ion binding]; other site
1198114005253	dimer interface [polypeptide binding]; other site
1198114005254	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114005255	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114005256	metal ion-dependent adhesion site (MIDAS); other site
1198114005257	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1198114005258	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114005259	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114005260	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114005261	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
1198114005262	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1198114005263	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276
1198114005264	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1198114005265	putative NAD(P) binding site [chemical binding]; other site
1198114005266	CAAX protease self-immunity; Region: Abi; pfam02517
1198114005267	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1198114005268	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114005269	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_4; cd07822
1198114005270	putative hydrophobic ligand binding site [chemical binding]; other site
1198114005271	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
1198114005272	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1198114005273	Putative catalytic domain of Synechocystis sp. Sll1306 protein and other bacterial homologs; Region: CE4_Sll1306_like; cd10978
1198114005274	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
1198114005275	putative active site [active]
1198114005276	putative catalytic site [active]
1198114005277	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_4; cd07822
1198114005278	putative hydrophobic ligand binding site [chemical binding]; other site
1198114005279	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1198114005280	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1198114005281	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114005282	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114005283	short chain dehydrogenase; Provisional; Region: PRK06500
1198114005284	classical (c) SDRs; Region: SDR_c; cd05233
1198114005285	NAD(P) binding site [chemical binding]; other site
1198114005286	active site
1198114005287	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1198114005288	classical (c) SDRs; Region: SDR_c; cd05233
1198114005289	NAD(P) binding site [chemical binding]; other site
1198114005290	active site
1198114005291	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114005292	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114005293	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114005294	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1198114005295	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114005296	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1198114005297	dimerization interface [polypeptide binding]; other site
1198114005298	substrate binding pocket [chemical binding]; other site
1198114005299	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114005300	non-specific DNA binding site [nucleotide binding]; other site
1198114005301	salt bridge; other site
1198114005302	sequence-specific DNA binding site [nucleotide binding]; other site
1198114005303	RES domain; Region: RES; cl02411
1198114005304	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114005305	binding surface
1198114005306	TPR motif; other site
1198114005307	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
1198114005308	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1198114005309	metal ion-dependent adhesion site (MIDAS); other site
1198114005310	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
1198114005311	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
1198114005312	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
1198114005313	Escherichia coli YdjC-like family of  proteins; Region: YdjC; cd10808
1198114005314	putative active site [active]
1198114005315	YdjC motif; other site
1198114005316	Mg binding site [ion binding]; other site
1198114005317	putative homodimer interface [polypeptide binding]; other site
1198114005318	PIN domain; Region: PIN; pfam01850
1198114005319	putative active site [active]
1198114005320	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
1198114005321	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
1198114005322	excinuclease ABC subunit B; Provisional; Region: PRK05298
1198114005323	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114005324	ATP binding site [chemical binding]; other site
1198114005325	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114005326	nucleotide binding region [chemical binding]; other site
1198114005327	ATP-binding site [chemical binding]; other site
1198114005328	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1198114005329	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1198114005330	catalytic core [active]
1198114005331	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1198114005332	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1198114005333	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114005334	motif II; other site
1198114005335	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1198114005336	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1198114005337	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1198114005338	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114005339	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114005340	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1198114005341	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114005342	catalytic residues [active]
1198114005343	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1198114005344	LexA repressor; Validated; Region: PRK00215
1198114005345	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1198114005346	Catalytic site [active]
1198114005347	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114005348	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114005349	active site
1198114005350	phosphorylation site [posttranslational modification]
1198114005351	intermolecular recognition site; other site
1198114005352	dimerization interface [polypeptide binding]; other site
1198114005353	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114005354	DNA binding site [nucleotide binding]
1198114005355	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114005356	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114005357	Walker A motif; other site
1198114005358	ATP binding site [chemical binding]; other site
1198114005359	Walker B motif; other site
1198114005360	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1198114005361	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
1198114005362	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1198114005363	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1198114005364	active site
1198114005365	HIGH motif; other site
1198114005366	nucleotide binding site [chemical binding]; other site
1198114005367	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1198114005368	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1198114005369	active site
1198114005370	KMSKS motif; other site
1198114005371	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1198114005372	tRNA binding surface [nucleotide binding]; other site
1198114005373	anticodon binding site; other site
1198114005374	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1198114005375	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114005376	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1198114005377	dimerization interface [polypeptide binding]; other site
1198114005378	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1198114005379	dimer interface [polypeptide binding]; other site
1198114005380	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1198114005381	putative CheW interface [polypeptide binding]; other site
1198114005382	Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890
1198114005383	putative active site [active]
1198114005384	putative metal binding residues [ion binding]; other site
1198114005385	signature motif; other site
1198114005386	putative triphosphate binding site [ion binding]; other site
1198114005387	dimer interface [polypeptide binding]; other site
1198114005388	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1198114005389	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1198114005390	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1198114005391	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
1198114005392	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1198114005393	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
1198114005394	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1198114005395	Cytochrome P450; Region: p450; cl12078
1198114005396	thymidylate kinase; Validated; Region: tmk; PRK00698
1198114005397	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1198114005398	TMP-binding site; other site
1198114005399	ATP-binding site [chemical binding]; other site
1198114005400	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1198114005401	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1198114005402	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1198114005403	trimer interface [polypeptide binding]; other site
1198114005404	active site
1198114005405	UDP-GlcNAc binding site [chemical binding]; other site
1198114005406	lipid binding site [chemical binding]; lipid-binding site
1198114005407	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4994
1198114005408	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1198114005409	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1198114005410	active site
1198114005411	NTP binding site [chemical binding]; other site
1198114005412	metal binding triad [ion binding]; metal-binding site
1198114005413	Predicted flavoprotein [General function prediction only]; Region: COG0431
1198114005414	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1198114005415	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386
1198114005416	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
1198114005417	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
1198114005418	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
1198114005419	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1198114005420	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
1198114005421	predicted active site [active]
1198114005422	catalytic triad [active]
1198114005423	Uncharacterized protein conserved in bacteria (DUF2059); Region: DUF2059; cl01243
1198114005424	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114005425	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114005426	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114005427	Domain of unknown function DUF87; Region: DUF87; pfam01935
1198114005428	AAA-like domain; Region: AAA_10; pfam12846
1198114005429	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1198114005430	SIR2-like domain; Region: SIR2_2; pfam13289
1198114005431	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
1198114005432	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1198114005433	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
1198114005434	active site
1198114005435	multimer interface [polypeptide binding]; other site
1198114005436	DNA polymerase IV; Reviewed; Region: PRK03103
1198114005437	Y-family of DNA polymerases; Region: PolY; cd00424
1198114005438	active site
1198114005439	DNA binding site [nucleotide binding]
1198114005440	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1198114005441	CoenzymeA binding site [chemical binding]; other site
1198114005442	subunit interaction site [polypeptide binding]; other site
1198114005443	PHB binding site; other site
1198114005444	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1198114005445	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114005446	ATP binding site [chemical binding]; other site
1198114005447	putative Mg++ binding site [ion binding]; other site
1198114005448	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114005449	nucleotide binding region [chemical binding]; other site
1198114005450	ATP-binding site [chemical binding]; other site
1198114005451	HRDC domain; Region: HRDC; pfam00570
1198114005452	HRDC domain; Region: HRDC; pfam00570
1198114005453	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1198114005454	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1198114005455	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1198114005456	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1198114005457	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
1198114005458	xanthine dehydrogenase E subunit; Region: pucE; TIGR03198
1198114005459	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1198114005460	catalytic loop [active]
1198114005461	iron binding site [ion binding]; other site
1198114005462	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1198114005463	Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939
1198114005464	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
1198114005465	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1198114005466	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1198114005467	GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925
1198114005468	dimerization interface [polypeptide binding]; other site
1198114005469	active site
1198114005470	Beta-propeller repeat; Region: SBBP; pfam06739
1198114005471	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1198114005472	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114005473	motif II; other site
1198114005474	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1198114005475	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1198114005476	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114005477	homodimer interface [polypeptide binding]; other site
1198114005478	catalytic residue [active]
1198114005479	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1198114005480	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1198114005481	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1198114005482	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
1198114005483	HlyD family secretion protein; Region: HlyD; pfam00529
1198114005484	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114005485	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114005486	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1198114005487	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114005488	H+ Antiporter protein; Region: 2A0121; TIGR00900
1198114005489	putative substrate translocation pore; other site
1198114005490	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1198114005491	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114005492	motif II; other site
1198114005493	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1198114005494	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1198114005495	active site
1198114005496	ATP binding site [chemical binding]; other site
1198114005497	substrate binding site [chemical binding]; other site
1198114005498	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1198114005499	substrate binding site [chemical binding]; other site
1198114005500	activation loop (A-loop); other site
1198114005501	activation loop (A-loop); other site
1198114005502	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114005503	binding surface
1198114005504	TPR motif; other site
1198114005505	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1198114005506	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1198114005507	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1198114005508	protein binding site [polypeptide binding]; other site
1198114005509	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1198114005510	protein binding site [polypeptide binding]; other site
1198114005511	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1198114005512	EamA-like transporter family; Region: EamA; pfam00892
1198114005513	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1198114005514	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1198114005515	active site
1198114005516	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1198114005517	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1198114005518	Transposase IS200 like; Region: Y1_Tnp; cl00848
1198114005519	signal recognition particle protein; Provisional; Region: PRK10867
1198114005520	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1198114005521	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1198114005522	P loop; other site
1198114005523	GTP binding site [chemical binding]; other site
1198114005524	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1198114005525	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1198114005526	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114005527	active site
1198114005528	DNA binding site [nucleotide binding]
1198114005529	Int/Topo IB signature motif; other site
1198114005530	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114005531	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1198114005532	active site
1198114005533	DNA binding site [nucleotide binding]
1198114005534	Int/Topo IB signature motif; other site
1198114005535	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114005536	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114005537	dimer interface [polypeptide binding]; other site
1198114005538	phosphorylation site [posttranslational modification]
1198114005539	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114005540	ATP binding site [chemical binding]; other site
1198114005541	G-X-G motif; other site
1198114005542	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114005543	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114005544	active site
1198114005545	phosphorylation site [posttranslational modification]
1198114005546	intermolecular recognition site; other site
1198114005547	dimerization interface [polypeptide binding]; other site
1198114005548	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114005549	Walker A motif; other site
1198114005550	ATP binding site [chemical binding]; other site
1198114005551	Walker B motif; other site
1198114005552	arginine finger; other site
1198114005553	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114005554	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1198114005555	active site residue [active]
1198114005556	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1198114005557	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114005558	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
1198114005559	Repair protein; Region: Repair_PSII; pfam04536
1198114005560	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1198114005561	MgtE intracellular N domain; Region: MgtE_N; smart00924
1198114005562	FOG: CBS domain [General function prediction only]; Region: COG0517
1198114005563	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1198114005564	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
1198114005565	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1198114005566	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1198114005567	active site
1198114005568	8-oxo-dGMP binding site [chemical binding]; other site
1198114005569	nudix motif; other site
1198114005570	metal binding site [ion binding]; metal-binding site
1198114005571	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1198114005572	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1198114005573	Uncharacterized stress protein (general stress protein 26) [General function prediction only]; Region: COG3871
1198114005574	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1198114005575	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1198114005576	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1198114005577	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1198114005578	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1198114005579	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
1198114005580	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114005581	FeS/SAM binding site; other site
1198114005582	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1198114005583	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1198114005584	putative substrate binding pocket [chemical binding]; other site
1198114005585	dimer interface [polypeptide binding]; other site
1198114005586	phosphate binding site [ion binding]; other site
1198114005587	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
1198114005588	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
1198114005589	DoxX; Region: DoxX; pfam07681
1198114005590	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1198114005591	iron-sulfur cluster [ion binding]; other site
1198114005592	[2Fe-2S] cluster binding site [ion binding]; other site
1198114005593	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1198114005594	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1198114005595	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1198114005596	catalytic site [active]
1198114005597	subunit interface [polypeptide binding]; other site
1198114005598	Transposase IS200 like; Region: Y1_Tnp; cl00848
1198114005599	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1198114005600	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1198114005601	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1198114005602	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1198114005603	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1198114005604	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1198114005605	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1198114005606	IMP binding site; other site
1198114005607	dimer interface [polypeptide binding]; other site
1198114005608	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1198114005609	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1198114005610	inhibitor site; inhibition site
1198114005611	active site
1198114005612	dimer interface [polypeptide binding]; other site
1198114005613	catalytic residue [active]
1198114005614	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1198114005615	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114005616	binding surface
1198114005617	TPR motif; other site
1198114005618	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1198114005619	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1198114005620	ligand binding site [chemical binding]; other site
1198114005621	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
1198114005622	TolB amino-terminal domain; Region: TolB_N; pfam04052
1198114005623	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114005624	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114005625	Uncharacterized conserved protein [Function unknown]; Region: COG5613
1198114005626	TonB C terminal; Region: TonB_2; pfam13103
1198114005627	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1198114005628	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1198114005629	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1198114005630	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1198114005631	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114005632	Walker A/P-loop; other site
1198114005633	ATP binding site [chemical binding]; other site
1198114005634	Q-loop/lid; other site
1198114005635	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1198114005636	ABC transporter signature motif; other site
1198114005637	Walker B; other site
1198114005638	D-loop; other site
1198114005639	H-loop/switch region; other site
1198114005640	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1198114005641	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1198114005642	squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507
1198114005643	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
1198114005644	Active site cavity [active]
1198114005645	catalytic acid [active]
1198114005646	hopanoid biosynthesis associated radical SAM protein HpnH; Region: HpnH; TIGR03470
1198114005647	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114005648	FeS/SAM binding site; other site
1198114005649	Domain of unknown function (DUF3463); Region: DUF3463; pfam11946
1198114005650	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
1198114005651	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
1198114005652	putative NADP binding site [chemical binding]; other site
1198114005653	putative substrate binding site [chemical binding]; other site
1198114005654	active site
1198114005655	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1198114005656	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1198114005657	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1198114005658	NAD(P) binding site [chemical binding]; other site
1198114005659	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1198114005660	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114005661	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
1198114005662	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1198114005663	hydrophobic ligand binding site; other site
1198114005664	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1198114005665	dimerization interface [polypeptide binding]; other site
1198114005666	putative DNA binding site [nucleotide binding]; other site
1198114005667	putative Zn2+ binding site [ion binding]; other site
1198114005668	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114005669	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114005670	metal binding site [ion binding]; metal-binding site
1198114005671	active site
1198114005672	I-site; other site
1198114005673	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1198114005674	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1198114005675	active site
1198114005676	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1198114005677	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1198114005678	minor groove reading motif; other site
1198114005679	helix-hairpin-helix signature motif; other site
1198114005680	substrate binding pocket [chemical binding]; other site
1198114005681	active site
1198114005682	Chlorite dismutase; Region: Chlor_dismutase; pfam06778
1198114005683	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1198114005684	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1198114005685	Myo-inositol-1-phosphate synthase [Lipid metabolism]; Region: INO1; COG1260
1198114005686	Myo-inositol-1-phosphate synthase; Region: NAD_binding_5; pfam07994
1198114005687	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1198114005688	G1 box; other site
1198114005689	GTP/Mg2+ binding site [chemical binding]; other site
1198114005690	Switch I region; other site
1198114005691	G2 box; other site
1198114005692	G3 box; other site
1198114005693	Switch II region; other site
1198114005694	G4 box; other site
1198114005695	G5 box; other site
1198114005696	NHL repeat; Region: NHL; pfam01436
1198114005697	NHL repeat; Region: NHL; pfam01436
1198114005698	NHL repeat; Region: NHL; pfam01436
1198114005699	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
1198114005700	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1198114005701	Cytochrome C biogenesis protein; Region: CcmH; cl01179
1198114005702	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
1198114005703	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1198114005704	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114005705	active site
1198114005706	phosphorylation site [posttranslational modification]
1198114005707	intermolecular recognition site; other site
1198114005708	dimerization interface [polypeptide binding]; other site
1198114005709	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u2; cd11478
1198114005710	Na binding site [ion binding]; other site
1198114005711	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1198114005712	Tetraspanin family; Region: Tetraspannin; pfam00335
1198114005713	PAS fold; Region: PAS_4; pfam08448
1198114005714	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114005715	PAS fold; Region: PAS_3; pfam08447
1198114005716	putative active site [active]
1198114005717	heme pocket [chemical binding]; other site
1198114005718	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114005719	KH domain; Region: KH_4; pfam13083
1198114005720	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1198114005721	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1198114005722	active site
1198114005723	ATP binding site [chemical binding]; other site
1198114005724	substrate binding site [chemical binding]; other site
1198114005725	activation loop (A-loop); other site
1198114005726	Predicted integral membrane protein [Function unknown]; Region: COG5616
1198114005727	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114005728	TPR motif; other site
1198114005729	binding surface
1198114005730	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114005731	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114005732	TPR motif; other site
1198114005733	binding surface
1198114005734	enolase; Provisional; Region: eno; PRK00077
1198114005735	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1198114005736	dimer interface [polypeptide binding]; other site
1198114005737	metal binding site [ion binding]; metal-binding site
1198114005738	substrate binding pocket [chemical binding]; other site
1198114005739	TadE-like protein; Region: TadE; pfam07811
1198114005740	Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400
1198114005741	BioY family; Region: BioY; pfam02632
1198114005742	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
1198114005743	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1198114005744	Septum formation initiator; Region: DivIC; pfam04977
1198114005745	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1198114005746	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114005747	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1198114005748	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1198114005749	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114005750	Walker A/P-loop; other site
1198114005751	ATP binding site [chemical binding]; other site
1198114005752	Q-loop/lid; other site
1198114005753	ABC transporter signature motif; other site
1198114005754	Walker B; other site
1198114005755	D-loop; other site
1198114005756	H-loop/switch region; other site
1198114005757	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1198114005758	Permease; Region: Permease; pfam02405
1198114005759	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1198114005760	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1198114005761	NAD(P) binding site [chemical binding]; other site
1198114005762	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
1198114005763	active site lid residues [active]
1198114005764	substrate binding pocket [chemical binding]; other site
1198114005765	catalytic residues [active]
1198114005766	substrate-Mg2+ binding site; other site
1198114005767	aspartate-rich region 1; other site
1198114005768	aspartate-rich region 2; other site
1198114005769	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
1198114005770	active site lid residues [active]
1198114005771	substrate binding pocket [chemical binding]; other site
1198114005772	catalytic residues [active]
1198114005773	substrate-Mg2+ binding site; other site
1198114005774	aspartate-rich region 1; other site
1198114005775	aspartate-rich region 2; other site
1198114005776	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114005777	squalene-associated FAD-dependent desaturase; Region: HpnE; TIGR03467
1198114005778	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
1198114005779	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
1198114005780	Uncharacterized protein family UPF0546; Region: UPF0546; pfam10639
1198114005781	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
1198114005782	B12 binding domain; Region: B12-binding; pfam02310
1198114005783	B12 binding site [chemical binding]; other site
1198114005784	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114005785	FeS/SAM binding site; other site
1198114005786	Outer membrane efflux protein; Region: OEP; pfam02321
1198114005787	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114005788	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114005789	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114005790	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1198114005791	DHH family; Region: DHH; pfam01368
1198114005792	DHHA1 domain; Region: DHHA1; pfam02272
1198114005793	Protein of unknown function (DUF507); Region: DUF507; cl01112
1198114005794	Protein of unknown function (DUF507); Region: DUF507; cl01112
1198114005795	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114005796	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114005797	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114005798	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114005799	active site
1198114005800	catalytic tetrad [active]
1198114005801	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1198114005802	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1198114005803	NAD(P) binding site [chemical binding]; other site
1198114005804	catalytic residues [active]
1198114005805	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
1198114005806	amphipathic channel; other site
1198114005807	Asn-Pro-Ala signature motifs; other site
1198114005808	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1198114005809	glycerol kinase; Provisional; Region: glpK; PRK00047
1198114005810	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1198114005811	N- and C-terminal domain interface [polypeptide binding]; other site
1198114005812	active site
1198114005813	MgATP binding site [chemical binding]; other site
1198114005814	catalytic site [active]
1198114005815	metal binding site [ion binding]; metal-binding site
1198114005816	glycerol binding site [chemical binding]; other site
1198114005817	homotetramer interface [polypeptide binding]; other site
1198114005818	homodimer interface [polypeptide binding]; other site
1198114005819	FBP binding site [chemical binding]; other site
1198114005820	protein IIAGlc interface [polypeptide binding]; other site
1198114005821	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1198114005822	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114005823	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114005824	sensory histidine kinase AtoS; Provisional; Region: PRK11360
1198114005825	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1198114005826	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114005827	ATP binding site [chemical binding]; other site
1198114005828	G-X-G motif; other site
1198114005829	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114005830	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114005831	active site
1198114005832	phosphorylation site [posttranslational modification]
1198114005833	intermolecular recognition site; other site
1198114005834	dimerization interface [polypeptide binding]; other site
1198114005835	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114005836	Walker A motif; other site
1198114005837	ATP binding site [chemical binding]; other site
1198114005838	Walker B motif; other site
1198114005839	arginine finger; other site
1198114005840	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114005841	Outer membrane efflux protein; Region: OEP; pfam02321
1198114005842	Outer membrane efflux protein; Region: OEP; pfam02321
1198114005843	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114005844	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114005845	Walker A/P-loop; other site
1198114005846	ATP binding site [chemical binding]; other site
1198114005847	Q-loop/lid; other site
1198114005848	ABC transporter signature motif; other site
1198114005849	Walker B; other site
1198114005850	D-loop; other site
1198114005851	H-loop/switch region; other site
1198114005852	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
1198114005853	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114005854	FtsX-like permease family; Region: FtsX; pfam02687
1198114005855	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114005856	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
1198114005857	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114005858	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114005859	FtsX-like permease family; Region: FtsX; pfam02687
1198114005860	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114005861	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114005862	Walker A/P-loop; other site
1198114005863	ATP binding site [chemical binding]; other site
1198114005864	Q-loop/lid; other site
1198114005865	ABC transporter signature motif; other site
1198114005866	Walker B; other site
1198114005867	D-loop; other site
1198114005868	H-loop/switch region; other site
1198114005869	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
1198114005870	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114005871	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1198114005872	beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431
1198114005873	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1198114005874	Bacterial transcriptional regulator; Region: IclR; pfam01614
1198114005875	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1198114005876	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1198114005877	active site
1198114005878	dimer interface [polypeptide binding]; other site
1198114005879	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1198114005880	dimer interface [polypeptide binding]; other site
1198114005881	active site
1198114005882	Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; Region: PRX_like2; cd02970
1198114005883	putative catalytic residues [active]
1198114005884	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
1198114005885	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1198114005886	TPP-binding site [chemical binding]; other site
1198114005887	tetramer interface [polypeptide binding]; other site
1198114005888	heterodimer interface [polypeptide binding]; other site
1198114005889	phosphorylation loop region [posttranslational modification]
1198114005890	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1198114005891	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1198114005892	alpha subunit interface [polypeptide binding]; other site
1198114005893	TPP binding site [chemical binding]; other site
1198114005894	heterodimer interface [polypeptide binding]; other site
1198114005895	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1198114005896	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1198114005897	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1198114005898	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
1198114005899	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
1198114005900	catalytic residues [active]
1198114005901	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
1198114005902	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114005903	GAF domain; Region: GAF; pfam01590
1198114005904	PAS fold; Region: PAS_4; pfam08448
1198114005905	PAS fold; Region: PAS_4; pfam08448
1198114005906	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114005907	putative active site [active]
1198114005908	heme pocket [chemical binding]; other site
1198114005909	Outer membrane efflux protein; Region: OEP; pfam02321
1198114005910	Outer membrane efflux protein; Region: OEP; pfam02321
1198114005911	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1198114005912	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1198114005913	dimerization interface 3.5A [polypeptide binding]; other site
1198114005914	active site
1198114005915	M20 Peptidases, Poly(aspartic acid) hydrolase-like proteins; Region: M20_PAAh_like; cd03896
1198114005916	putative metal binding site [ion binding]; other site
1198114005917	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1198114005918	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1198114005919	Di-iron ligands [ion binding]; other site
1198114005920	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1198114005921	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1198114005922	Acetokinase family; Region: Acetate_kinase; cl17229
1198114005923	propionate/acetate kinase; Provisional; Region: PRK12379
1198114005924	putative phosphoketolase; Provisional; Region: PRK05261
1198114005925	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
1198114005926	TPP-binding site; other site
1198114005927	XFP C-terminal domain; Region: XFP_C; pfam09363
1198114005928	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1198114005929	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1198114005930	interface (dimer of trimers) [polypeptide binding]; other site
1198114005931	Substrate-binding/catalytic site; other site
1198114005932	Zn-binding sites [ion binding]; other site
1198114005933	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1198114005934	SmpB-tmRNA interface; other site
1198114005935	TPR repeat; Region: TPR_11; pfam13414
1198114005936	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
1198114005937	Secretin and TonB N terminus short domain; Region: STN; smart00965
1198114005938	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1198114005939	Cohesin domain, interaction parter of dockerin; Region: cohesin_like; cd08546
1198114005940	dockerin binding interface; other site
1198114005941	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1198114005942	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1198114005943	Peptidase family M48; Region: Peptidase_M48; pfam01435
1198114005944	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
1198114005945	active site
1198114005946	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1198114005947	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1198114005948	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1198114005949	Walker A/P-loop; other site
1198114005950	ATP binding site [chemical binding]; other site
1198114005951	Q-loop/lid; other site
1198114005952	ABC transporter signature motif; other site
1198114005953	Walker B; other site
1198114005954	D-loop; other site
1198114005955	H-loop/switch region; other site
1198114005956	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1198114005957	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1198114005958	tetramer interface [polypeptide binding]; other site
1198114005959	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114005960	catalytic residue [active]
1198114005961	CHASE3 domain; Region: CHASE3; cl05000
1198114005962	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1198114005963	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114005964	putative active site [active]
1198114005965	heme pocket [chemical binding]; other site
1198114005966	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114005967	dimer interface [polypeptide binding]; other site
1198114005968	phosphorylation site [posttranslational modification]
1198114005969	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114005970	ATP binding site [chemical binding]; other site
1198114005971	Mg2+ binding site [ion binding]; other site
1198114005972	G-X-G motif; other site
1198114005973	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114005974	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114005975	active site
1198114005976	phosphorylation site [posttranslational modification]
1198114005977	intermolecular recognition site; other site
1198114005978	dimerization interface [polypeptide binding]; other site
1198114005979	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114005980	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114005981	active site
1198114005982	phosphorylation site [posttranslational modification]
1198114005983	intermolecular recognition site; other site
1198114005984	dimerization interface [polypeptide binding]; other site
1198114005985	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114005986	DNA binding site [nucleotide binding]
1198114005987	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1198114005988	PAS domain; Region: PAS; smart00091
1198114005989	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114005990	dimer interface [polypeptide binding]; other site
1198114005991	phosphorylation site [posttranslational modification]
1198114005992	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114005993	ATP binding site [chemical binding]; other site
1198114005994	Mg2+ binding site [ion binding]; other site
1198114005995	G-X-G motif; other site
1198114005996	PBP superfamily domain; Region: PBP_like_2; cl17296
1198114005997	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1198114005998	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114005999	dimer interface [polypeptide binding]; other site
1198114006000	conserved gate region; other site
1198114006001	putative PBP binding loops; other site
1198114006002	ABC-ATPase subunit interface; other site
1198114006003	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1198114006004	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114006005	dimer interface [polypeptide binding]; other site
1198114006006	conserved gate region; other site
1198114006007	putative PBP binding loops; other site
1198114006008	ABC-ATPase subunit interface; other site
1198114006009	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1198114006010	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1198114006011	Walker A/P-loop; other site
1198114006012	ATP binding site [chemical binding]; other site
1198114006013	Q-loop/lid; other site
1198114006014	ABC transporter signature motif; other site
1198114006015	Walker B; other site
1198114006016	D-loop; other site
1198114006017	H-loop/switch region; other site
1198114006018	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1198114006019	PhoU domain; Region: PhoU; pfam01895
1198114006020	PhoU domain; Region: PhoU; pfam01895
1198114006021	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
1198114006022	Part of AAA domain; Region: AAA_19; pfam13245
1198114006023	Family description; Region: UvrD_C_2; pfam13538
1198114006024	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1198114006025	probable DNA repair protein; Region: TIGR03623
1198114006026	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1198114006027	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1198114006028	Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604
1198114006029	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1198114006030	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1198114006031	Cu(I) binding site [ion binding]; other site
1198114006032	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1198114006033	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1198114006034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114006035	Walker A/P-loop; other site
1198114006036	ATP binding site [chemical binding]; other site
1198114006037	Q-loop/lid; other site
1198114006038	ABC transporter signature motif; other site
1198114006039	Walker B; other site
1198114006040	D-loop; other site
1198114006041	H-loop/switch region; other site
1198114006042	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1198114006043	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1198114006044	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1198114006045	SEC-C motif; Region: SEC-C; pfam02810
1198114006046	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114006047	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1198114006048	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114006049	S-adenosylmethionine binding site [chemical binding]; other site
1198114006050	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1198114006051	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114006052	putative substrate translocation pore; other site
1198114006053	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114006054	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114006055	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114006056	metal binding site [ion binding]; metal-binding site
1198114006057	hypothetical protein; Provisional; Region: PRK08201
1198114006058	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
1198114006059	metal binding site [ion binding]; metal-binding site
1198114006060	putative dimer interface [polypeptide binding]; other site
1198114006061	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1198114006062	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1198114006063	GTP binding site; other site
1198114006064	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1198114006065	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1198114006066	Walker A/P-loop; other site
1198114006067	ATP binding site [chemical binding]; other site
1198114006068	Q-loop/lid; other site
1198114006069	ABC transporter signature motif; other site
1198114006070	Walker B; other site
1198114006071	D-loop; other site
1198114006072	H-loop/switch region; other site
1198114006073	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1198114006074	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1198114006075	NAD synthetase; Provisional; Region: PRK13981
1198114006076	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
1198114006077	multimer interface [polypeptide binding]; other site
1198114006078	active site
1198114006079	catalytic triad [active]
1198114006080	protein interface 1 [polypeptide binding]; other site
1198114006081	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1198114006082	homodimer interface [polypeptide binding]; other site
1198114006083	NAD binding pocket [chemical binding]; other site
1198114006084	ATP binding pocket [chemical binding]; other site
1198114006085	Mg binding site [ion binding]; other site
1198114006086	active-site loop [active]
1198114006087	Thioredoxin; Region: Thioredoxin_4; cl17273
1198114006088	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
1198114006089	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
1198114006090	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114006091	RNA polymerase factor sigma-70; Validated; Region: PRK09047
1198114006092	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1198114006093	DNA binding residues [nucleotide binding]
1198114006094	kynureninase; Region: kynureninase; TIGR01814
1198114006095	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114006096	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114006097	catalytic residue [active]
1198114006098	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1198114006099	OsmC-like protein; Region: OsmC; pfam02566
1198114006100	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1198114006101	Zn2+ binding site [ion binding]; other site
1198114006102	Mg2+ binding site [ion binding]; other site
1198114006103	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1198114006104	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1198114006105	conserved cys residue [active]
1198114006106	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114006107	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114006108	alpha-galactosidase; Region: PLN02808; cl17638
1198114006109	alpha-galactosidase; Region: PLN02808; cl17638
1198114006110	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006111	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114006112	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1198114006113	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
1198114006114	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
1198114006115	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114006116	D-galactonate transporter; Region: 2A0114; TIGR00893
1198114006117	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114006118	putative substrate translocation pore; other site
1198114006119	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
1198114006120	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1198114006121	DXD motif; other site
1198114006122	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1198114006123	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1198114006124	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1198114006125	PAS domain; Region: PAS_9; pfam13426
1198114006126	PAS fold; Region: PAS_4; pfam08448
1198114006127	KH domain; Region: KH_4; pfam13083
1198114006128	Predicted permeases [General function prediction only]; Region: COG0795
1198114006129	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1198114006130	Predicted permeases [General function prediction only]; Region: COG0795
1198114006131	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1198114006132	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
1198114006133	gluconate 5-dehydrogenase; Provisional; Region: PRK08213
1198114006134	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1198114006135	NADP binding site [chemical binding]; other site
1198114006136	homodimer interface [polypeptide binding]; other site
1198114006137	active site
1198114006138	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
1198114006139	homotrimer interaction site [polypeptide binding]; other site
1198114006140	putative active site [active]
1198114006141	Protein of unknown function (DUF3738); Region: DUF3738; cl11887
1198114006142	soil-associated protein, TIGR03435 family; Region: Soli_TIGR03435
1198114006143	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1198114006144	classical (c) SDRs; Region: SDR_c; cd05233
1198114006145	NAD(P) binding site [chemical binding]; other site
1198114006146	active site
1198114006147	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114006148	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114006149	Zinc dependent phospholipase C; Region: Zn_dep_PLPC; pfam00882
1198114006150	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1198114006151	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1198114006152	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1198114006153	substrate binding site [chemical binding]; other site
1198114006154	ATP binding site [chemical binding]; other site
1198114006155	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
1198114006156	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1198114006157	active site
1198114006158	intersubunit interface [polypeptide binding]; other site
1198114006159	catalytic residue [active]
1198114006160	Alginate lyase; Region: Alginate_lyase; pfam05426
1198114006161	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1198114006162	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1198114006163	substrate binding pocket [chemical binding]; other site
1198114006164	membrane-bound complex binding site; other site
1198114006165	hinge residues; other site
1198114006166	Phosphoesterase family; Region: Phosphoesterase; pfam04185
1198114006167	Phosphoesterase family; Region: Phosphoesterase; pfam04185
1198114006168	Vitamin K-dependent gamma-carboxylase; Region: VKG_Carbox; cl02773
1198114006169	Putative addiction module component; Region: Unstab_antitox; cl09921
1198114006170	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
1198114006171	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u2; cd11478
1198114006172	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1198114006173	Na binding site [ion binding]; other site
1198114006174	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
1198114006175	pyrroline-5-carboxylate reductase; Region: PLN02688
1198114006176	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1198114006177	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
1198114006178	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1198114006179	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1198114006180	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114006181	bacillithiol system oxidoreductase, YphP/YqiW family; Region: YphP_YqiW; TIGR04191
1198114006182	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1198114006183	MarR family; Region: MarR_2; pfam12802
1198114006184	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1198114006185	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1198114006186	dimer interface [polypeptide binding]; other site
1198114006187	active site
1198114006188	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13903
1198114006189	FAD binding domain; Region: FAD_binding_4; pfam01565
1198114006190	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1198114006191	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114006192	thiamine ABC transporter, ATP-binding protein; Region: thiQ; TIGR01277
1198114006193	Walker A/P-loop; other site
1198114006194	ATP binding site [chemical binding]; other site
1198114006195	Q-loop/lid; other site
1198114006196	ABC transporter signature motif; other site
1198114006197	Walker B; other site
1198114006198	D-loop; other site
1198114006199	H-loop/switch region; other site
1198114006200	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114006201	dimer interface [polypeptide binding]; other site
1198114006202	conserved gate region; other site
1198114006203	putative PBP binding loops; other site
1198114006204	ABC-ATPase subunit interface; other site
1198114006205	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1198114006206	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1198114006207	threonine synthase; Validated; Region: PRK06260
1198114006208	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
1198114006209	homodimer interface [polypeptide binding]; other site
1198114006210	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114006211	catalytic residue [active]
1198114006212	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1198114006213	active site
1198114006214	phosphorylation site [posttranslational modification]
1198114006215	intermolecular recognition site; other site
1198114006216	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1198114006217	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1198114006218	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cl04270
1198114006219	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114006220	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1198114006221	NAD(P) binding site [chemical binding]; other site
1198114006222	active site
1198114006223	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1198114006224	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114006225	dimer interface [polypeptide binding]; other site
1198114006226	conserved gate region; other site
1198114006227	putative PBP binding loops; other site
1198114006228	ABC-ATPase subunit interface; other site
1198114006229	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1198114006230	active site
1198114006231	metal binding site [ion binding]; metal-binding site
1198114006232	homotetramer interface [polypeptide binding]; other site
1198114006233	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1198114006234	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114006235	dimer interface [polypeptide binding]; other site
1198114006236	conserved gate region; other site
1198114006237	putative PBP binding loops; other site
1198114006238	ABC-ATPase subunit interface; other site
1198114006239	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1198114006240	Domain of unknown function DUF21; Region: DUF21; pfam01595
1198114006241	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1198114006242	Transporter associated domain; Region: CorC_HlyC; smart01091
1198114006243	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1198114006244	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114006245	catalytic residues [active]
1198114006246	homoserine kinase; Provisional; Region: PRK01212
1198114006247	Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434
1198114006248	EAL domain; Region: EAL; pfam00563
1198114006249	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1198114006250	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1198114006251	NAD(P) binding site [chemical binding]; other site
1198114006252	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114006253	S-adenosylmethionine binding site [chemical binding]; other site
1198114006254	transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282
1198114006255	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
1198114006256	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
1198114006257	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114006258	FeS/SAM binding site; other site
1198114006259	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1198114006260	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1198114006261	Ligand binding site; other site
1198114006262	Putative Catalytic site; other site
1198114006263	DXD motif; other site
1198114006264	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114006265	Amidase; Region: Amidase; cl11426
1198114006266	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114006267	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1198114006268	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114006269	GAF domain; Region: GAF; pfam01590
1198114006270	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1198114006271	Gcd10p family; Region: Gcd10p; pfam04189
1198114006272	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1198114006273	intersubunit interface [polypeptide binding]; other site
1198114006274	active site
1198114006275	catalytic residue [active]
1198114006276	Domain of unknown function (DUF4130; Region: DUF4130; cl14836
1198114006277	Domain of unknown function (DUF4130; Region: DUF4130; pfam13566
1198114006278	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
1198114006279	Fe-S cluster binding site [ion binding]; other site
1198114006280	active site
1198114006281	Predicted DNA-binding protein with the Helix-hairpin-helix motif [General function prediction only]; Region: COG4277
1198114006282	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114006283	FeS/SAM binding site; other site
1198114006284	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1198114006285	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1198114006286	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1198114006287	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1198114006288	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1198114006289	active site
1198114006290	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
1198114006291	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
1198114006292	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1198114006293	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006294	TPR motif; other site
1198114006295	binding surface
1198114006296	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114006297	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006298	TPR motif; other site
1198114006299	binding surface
1198114006300	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1198114006301	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1198114006302	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114006303	ABC transporter signature motif; other site
1198114006304	Walker B; other site
1198114006305	D-loop; other site
1198114006306	H-loop/switch region; other site
1198114006307	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1198114006308	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1198114006309	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1198114006310	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1198114006311	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006312	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1198114006313	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; smart00813
1198114006314	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
1198114006315	substrate binding site [chemical binding]; other site
1198114006316	active site
1198114006317	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1198114006318	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1198114006319	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1198114006320	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006321	binding surface
1198114006322	TPR motif; other site
1198114006323	TPR repeat; Region: TPR_11; pfam13414
1198114006324	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006325	binding surface
1198114006326	TPR motif; other site
1198114006327	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006328	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114006329	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006330	binding surface
1198114006331	TPR motif; other site
1198114006332	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006333	binding surface
1198114006334	TPR motif; other site
1198114006335	Family description; Region: VCBS; pfam13517
1198114006336	Family description; Region: VCBS; pfam13517
1198114006337	Family description; Region: VCBS; pfam13517
1198114006338	Family description; Region: VCBS; pfam13517
1198114006339	Family description; Region: VCBS; pfam13517
1198114006340	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1198114006341	Sugar-binding cellulase-like; Region: Cellulase-like; pfam12876
1198114006342	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1198114006343	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1198114006344	TPR repeat; Region: TPR_11; pfam13414
1198114006345	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006346	binding surface
1198114006347	TPR motif; other site
1198114006348	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114006349	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006350	TPR motif; other site
1198114006351	binding surface
1198114006352	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006353	TPR motif; other site
1198114006354	binding surface
1198114006355	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1198114006356	binding surface
1198114006357	TPR motif; other site
1198114006358	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1198114006359	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1198114006360	DNA binding site [nucleotide binding]
1198114006361	domain linker motif; other site
1198114006362	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1198114006363	dimerization interface [polypeptide binding]; other site
1198114006364	ligand binding site [chemical binding]; other site
1198114006365	Domain of unknown function (DUF1793); Region: DUF1793; pfam08760
1198114006366	Family description; Region: VCBS; pfam13517
1198114006367	Family description; Region: VCBS; pfam13517
1198114006368	Family description; Region: VCBS; pfam13517
1198114006369	Family description; Region: VCBS; pfam13517
1198114006370	Family description; Region: VCBS; pfam13517
1198114006371	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1198114006372	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006373	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1198114006374	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006375	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1198114006376	ApbE family; Region: ApbE; pfam02424
1198114006377	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114006378	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114006379	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1198114006380	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1198114006381	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1198114006382	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1198114006383	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1198114006384	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114006385	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114006386	ligand binding site [chemical binding]; other site
1198114006387	flexible hinge region; other site
1198114006388	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1198114006389	putative switch regulator; other site
1198114006390	non-specific DNA interactions [nucleotide binding]; other site
1198114006391	DNA binding site [nucleotide binding]
1198114006392	sequence specific DNA binding site [nucleotide binding]; other site
1198114006393	putative cAMP binding site [chemical binding]; other site
1198114006394	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114006395	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114006396	active site
1198114006397	phosphorylation site [posttranslational modification]
1198114006398	intermolecular recognition site; other site
1198114006399	dimerization interface [polypeptide binding]; other site
1198114006400	menaquinone biosynthesis protein, SCO4550 family; Region: mena_SCO4550; TIGR03699
1198114006401	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1198114006402	FeS/SAM binding site; other site
1198114006403	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1198114006404	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114006405	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006406	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114006407	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114006408	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1198114006409	metal binding site 2 [ion binding]; metal-binding site
1198114006410	putative DNA binding helix; other site
1198114006411	metal binding site 1 [ion binding]; metal-binding site
1198114006412	dimer interface [polypeptide binding]; other site
1198114006413	structural Zn2+ binding site [ion binding]; other site
1198114006414	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1198114006415	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1198114006416	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1198114006417	acyl-activating enzyme (AAE) consensus motif; other site
1198114006418	AMP binding site [chemical binding]; other site
1198114006419	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1198114006420	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1198114006421	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1198114006422	active site
1198114006423	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1198114006424	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
1198114006425	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1198114006426	Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001
1198114006427	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1198114006428	inhibitor-cofactor binding pocket; inhibition site
1198114006429	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114006430	catalytic residue [active]
1198114006431	Condensation domain; Region: Condensation; pfam00668
1198114006432	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1198114006433	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1198114006434	The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116
1198114006435	acyl-activating enzyme (AAE) consensus motif; other site
1198114006436	AMP binding site [chemical binding]; other site
1198114006437	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1198114006438	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1198114006439	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1198114006440	The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116
1198114006441	acyl-activating enzyme (AAE) consensus motif; other site
1198114006442	AMP binding site [chemical binding]; other site
1198114006443	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1198114006444	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114006445	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
1198114006446	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114006447	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1198114006448	putative ADP-binding pocket [chemical binding]; other site
1198114006449	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114006450	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1198114006451	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1198114006452	Probable Catalytic site; other site
1198114006453	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1198114006454	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1198114006455	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1198114006456	trimer interface [polypeptide binding]; other site
1198114006457	active site
1198114006458	substrate binding site [chemical binding]; other site
1198114006459	CoA binding site [chemical binding]; other site
1198114006460	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1198114006461	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1198114006462	active site
1198114006463	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
1198114006464	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1198114006465	trimer interface [polypeptide binding]; other site
1198114006466	active site
1198114006467	substrate binding site [chemical binding]; other site
1198114006468	CoA binding site [chemical binding]; other site
1198114006469	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1198114006470	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1198114006471	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
1198114006472	SLBB domain; Region: SLBB; pfam10531
1198114006473	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1198114006474	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1198114006475	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1198114006476	anti sigma factor interaction site; other site
1198114006477	regulatory phosphorylation site [posttranslational modification]; other site
1198114006478	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1198114006479	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1198114006480	O-Antigen ligase; Region: Wzy_C; pfam04932
1198114006481	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1198114006482	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1198114006483	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1198114006484	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
1198114006485	DXD motif; other site
1198114006486	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114006487	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
1198114006488	dimer interface [polypeptide binding]; other site
1198114006489	substrate binding site [chemical binding]; other site
1198114006490	metal binding site [ion binding]; metal-binding site
1198114006491	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006492	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114006493	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114006494	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114006495	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114006496	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114006497	Walker A/P-loop; other site
1198114006498	ATP binding site [chemical binding]; other site
1198114006499	Q-loop/lid; other site
1198114006500	ABC transporter signature motif; other site
1198114006501	Walker B; other site
1198114006502	D-loop; other site
1198114006503	H-loop/switch region; other site
1198114006504	Deoxyribonuclease II; Region: DNase_II; pfam03265
1198114006505	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1198114006506	putative active site [active]
1198114006507	catalytic site [active]
1198114006508	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1198114006509	putative active site [active]
1198114006510	catalytic site [active]
1198114006511	amino acid transporter; Region: 2A0306; TIGR00909
1198114006512	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1198114006513	amino acid transporter; Region: 2A0306; TIGR00909
1198114006514	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1198114006515	thiamine phosphate binding site [chemical binding]; other site
1198114006516	active site
1198114006517	pyrophosphate binding site [ion binding]; other site
1198114006518	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1198114006519	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1198114006520	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1198114006521	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1198114006522	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1198114006523	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1198114006524	carboxyltransferase (CT) interaction site; other site
1198114006525	biotinylation site [posttranslational modification]; other site
1198114006526	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1198114006527	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1198114006528	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1198114006529	active site
1198114006530	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1198114006531	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1198114006532	putative active site [active]
1198114006533	putative metal binding site [ion binding]; other site
1198114006534	Helix-turn-helix domain; Region: HTH_17; pfam12728
1198114006535	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1198114006536	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1198114006537	TraB family; Region: TraB; pfam01963
1198114006538	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; pfam03767
1198114006539	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1198114006540	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1198114006541	acyl-activating enzyme (AAE) consensus motif; other site
1198114006542	putative AMP binding site [chemical binding]; other site
1198114006543	putative active site [active]
1198114006544	putative CoA binding site [chemical binding]; other site
1198114006545	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1198114006546	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1198114006547	active site
1198114006548	dimer interface [polypeptide binding]; other site
1198114006549	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1198114006550	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1198114006551	active site
1198114006552	FMN binding site [chemical binding]; other site
1198114006553	substrate binding site [chemical binding]; other site
1198114006554	3Fe-4S cluster binding site [ion binding]; other site
1198114006555	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1198114006556	domain interface; other site
1198114006557	Arginine repressor [Transcription]; Region: ArgR; COG1438
1198114006558	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1198114006559	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1198114006560	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1198114006561	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1198114006562	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
1198114006563	metal binding site [ion binding]; metal-binding site
1198114006564	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
1198114006565	nucleotide binding site [chemical binding]; other site
1198114006566	N-acetyl-L-glutamate binding site [chemical binding]; other site
1198114006567	acetylornithine aminotransferase; Provisional; Region: PRK02627
1198114006568	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1198114006569	inhibitor-cofactor binding pocket; inhibition site
1198114006570	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114006571	catalytic residue [active]
1198114006572	ornithine carbamoyltransferase; Provisional; Region: PRK00779
1198114006573	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1198114006574	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1198114006575	argininosuccinate synthase; Validated; Region: PRK05370
1198114006576	argininosuccinate synthase; Provisional; Region: PRK13820
1198114006577	argininosuccinate lyase; Provisional; Region: PRK00855
1198114006578	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1198114006579	active sites [active]
1198114006580	tetramer interface [polypeptide binding]; other site
1198114006581	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114006582	Coenzyme A binding pocket [chemical binding]; other site
1198114006583	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1198114006584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114006585	Walker A/P-loop; other site
1198114006586	ATP binding site [chemical binding]; other site
1198114006587	Q-loop/lid; other site
1198114006588	ABC transporter signature motif; other site
1198114006589	Walker B; other site
1198114006590	D-loop; other site
1198114006591	H-loop/switch region; other site
1198114006592	glutamate formiminotransferase; Region: FtcD; TIGR02024
1198114006593	Formiminotransferase domain, N-terminal subdomain; Region: FTCD_N; pfam07837
1198114006594	Formiminotransferase domain; Region: FTCD; pfam02971
1198114006595	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1198114006596	hypothetical protein; Validated; Region: PRK00110
1198114006597	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1198114006598	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1198114006599	active site
1198114006600	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1198114006601	substrate binding site [chemical binding]; other site
1198114006602	catalytic residues [active]
1198114006603	dimer interface [polypeptide binding]; other site
1198114006604	soil-associated protein, TIGR03435 family; Region: Soli_TIGR03435
1198114006605	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1198114006606	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1198114006607	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114006608	non-specific DNA binding site [nucleotide binding]; other site
1198114006609	salt bridge; other site
1198114006610	sequence-specific DNA binding site [nucleotide binding]; other site
1198114006611	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
1198114006612	PspC domain; Region: PspC; pfam04024
1198114006613	Protein of unknown function (DUF1453); Region: DUF1453; pfam07301
1198114006614	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114006615	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006616	TPR motif; other site
1198114006617	binding surface
1198114006618	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317
1198114006619	Cysteine-rich motif following a subset of SET domains; Region: PostSET; smart00508
1198114006620	Protein of unknown function (DUF433); Region: DUF433; cl01030
1198114006621	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
1198114006622	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114006623	Walker A motif; other site
1198114006624	ATP binding site [chemical binding]; other site
1198114006625	Walker B motif; other site
1198114006626	arginine finger; other site
1198114006627	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1198114006628	hypothetical protein; Validated; Region: PRK00153
1198114006629	recombination protein RecR; Reviewed; Region: recR; PRK00076
1198114006630	RecR protein; Region: RecR; pfam02132
1198114006631	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1198114006632	putative active site [active]
1198114006633	putative metal-binding site [ion binding]; other site
1198114006634	tetramer interface [polypeptide binding]; other site
1198114006635	Uncharacterized protein family (UPF0175); Region: UPF0175; cl01085
1198114006636	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
1198114006637	phosphoglyceromutase; Provisional; Region: PRK05434
1198114006638	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1198114006639	MASE1; Region: MASE1; cl17823
1198114006640	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114006641	PAS fold; Region: PAS_3; pfam08447
1198114006642	putative active site [active]
1198114006643	heme pocket [chemical binding]; other site
1198114006644	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114006645	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114006646	metal binding site [ion binding]; metal-binding site
1198114006647	active site
1198114006648	I-site; other site
1198114006649	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006650	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1198114006651	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1198114006652	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1198114006653	soil-associated protein, TIGR03435 family; Region: Soli_TIGR03435
1198114006654	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114006655	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114006656	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
1198114006657	putative ligand binding site [chemical binding]; other site
1198114006658	short chain dehydrogenase; Provisional; Region: PRK06197
1198114006659	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
1198114006660	putative NAD(P) binding site [chemical binding]; other site
1198114006661	active site
1198114006662	Predicted transcriptional regulators [Transcription]; Region: COG1733
1198114006663	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1198114006664	Helix-turn-helix domain; Region: HTH_17; pfam12728
1198114006665	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114006666	Walker A motif; other site
1198114006667	ATP binding site [chemical binding]; other site
1198114006668	Walker B motif; other site
1198114006669	Helix-turn-helix domain; Region: HTH_36; pfam13730
1198114006670	TIR domain; Region: TIR_2; pfam13676
1198114006671	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1198114006672	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114006673	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1198114006674	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1198114006675	active site
1198114006676	Phage terminase, small subunit; Region: Terminase_4; pfam05119
1198114006677	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
1198114006678	Phage-related protein [Function unknown]; Region: COG4695
1198114006679	Phage portal protein; Region: Phage_portal; pfam04860
1198114006680	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
1198114006681	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1198114006682	Phage capsid family; Region: Phage_capsid; pfam05065
1198114006683	phage conserved hypothetical protein, phiE125 gp8 family; Region: phage_chp_gp8; TIGR02215
1198114006684	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1198114006685	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1198114006686	oligomerization interface [polypeptide binding]; other site
1198114006687	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
1198114006688	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
1198114006689	GIY-YIG domain of uncharacterized hypothetical protein found in phycodnavirus PBCV-1 DNA virus, T. thermophila Tlr element eoncoding protein Tlr8p, and similar proteins found in bacteria; Region: GIY-YIG_HE_Tlr8p_PBC-V_like; cd10443
1198114006690	GIY-YIG motif/motif A; other site
1198114006691	putative active site [active]
1198114006692	putative metal binding site [ion binding]; other site
1198114006693	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1198114006694	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
1198114006695	active site
1198114006696	oxyanion hole [active]
1198114006697	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1198114006698	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1198114006699	catalytic residues [active]
1198114006700	RHS Repeat; Region: RHS_repeat; pfam05593
1198114006701	RHS Repeat; Region: RHS_repeat; pfam05593
1198114006702	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1198114006703	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1198114006704	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
1198114006705	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1198114006706	DNA binding site [nucleotide binding]
1198114006707	Int/Topo IB signature motif; other site
1198114006708	active site
1198114006709	catalytic residues [active]
1198114006710	Domain of unknown function (DUF1984); Region: Phytochelatin_C; pfam09328
1198114006711	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1198114006712	nucleophilic elbow; other site
1198114006713	catalytic triad; other site
1198114006714	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114006715	KH domain; Region: KH_4; pfam13083
1198114006716	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1198114006717	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114006718	active site
1198114006719	DNA binding site [nucleotide binding]
1198114006720	Int/Topo IB signature motif; other site
1198114006721	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
1198114006722	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1198114006723	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114006724	active site
1198114006725	DNA binding site [nucleotide binding]
1198114006726	Int/Topo IB signature motif; other site
1198114006727	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1198114006728	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114006729	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114006730	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114006731	Sortase D (SrtD) is a membrane transpeptidase found in gram-positive bacteria that anchors surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the surface protein substrate is cleaved...; Region: Sortase_D_4; cd05828
1198114006732	active site
1198114006733	catalytic site [active]
1198114006734	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1198114006735	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114006736	non-specific DNA binding site [nucleotide binding]; other site
1198114006737	salt bridge; other site
1198114006738	sequence-specific DNA binding site [nucleotide binding]; other site
1198114006739	Helix-turn-helix domain; Region: HTH_38; pfam13936
1198114006740	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1198114006741	Integrase core domain; Region: rve; pfam00665
1198114006742	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114006743	DNA-binding site [nucleotide binding]; DNA binding site
1198114006744	RNA-binding motif; other site
1198114006745	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114006746	DNA-binding site [nucleotide binding]; DNA binding site
1198114006747	RNA-binding motif; other site
1198114006748	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114006749	KH domain; Region: KH_4; pfam13083
1198114006750	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114006751	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114006752	ligand binding site [chemical binding]; other site
1198114006753	flexible hinge region; other site
1198114006754	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1198114006755	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114006756	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114006757	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114006758	CHC2 zinc finger; Region: zf-CHC2; cl17510
1198114006759	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1198114006760	active site
1198114006761	metal binding site [ion binding]; metal-binding site
1198114006762	interdomain interaction site; other site
1198114006763	integrase; Provisional; Region: int; PHA02601
1198114006764	Phage integrase family; Region: Phage_integrase; pfam00589
1198114006765	active site
1198114006766	DNA binding site [nucleotide binding]
1198114006767	Int/Topo IB signature motif; other site
1198114006768	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1198114006769	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1198114006770	binding surface
1198114006771	TPR motif; other site
1198114006772	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1198114006773	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1198114006774	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1198114006775	catalytic residue [active]
1198114006776	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1198114006777	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114006778	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114006779	DNA binding residues [nucleotide binding]
1198114006780	Putative zinc-finger; Region: zf-HC2; pfam13490
1198114006781	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1198114006782	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114006783	Coenzyme A binding pocket [chemical binding]; other site
1198114006784	Animal heme peroxidases and related proteins; Region: An_peroxidase_like; cl14561
1198114006785	heme binding site [chemical binding]; other site
1198114006786	substrate binding site [chemical binding]; other site
1198114006787	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1198114006788	homotrimer interface [polypeptide binding]; other site
1198114006789	Walker A motif; other site
1198114006790	GTP binding site [chemical binding]; other site
1198114006791	Walker B motif; other site
1198114006792	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1198114006793	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1198114006794	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1198114006795	catalytic triad [active]
1198114006796	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1198114006797	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1198114006798	putative dimer interface [polypeptide binding]; other site
1198114006799	active site pocket [active]
1198114006800	putative cataytic base [active]
1198114006801	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1198114006802	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1198114006803	catalytic core [active]
1198114006804	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1198114006805	cobyric acid synthase; Provisional; Region: PRK00784
1198114006806	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1198114006807	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1198114006808	catalytic triad [active]
1198114006809	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
1198114006810	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
1198114006811	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114006812	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1198114006813	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114006814	homodimer interface [polypeptide binding]; other site
1198114006815	catalytic residue [active]
1198114006816	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1198114006817	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1198114006818	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1198114006819	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1198114006820	active site
1198114006821	HIGH motif; other site
1198114006822	nucleotide binding site [chemical binding]; other site
1198114006823	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1198114006824	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1198114006825	tRNA binding surface [nucleotide binding]; other site
1198114006826	anticodon binding site; other site
1198114006827	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1198114006828	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1198114006829	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1198114006830	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1198114006831	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1198114006832	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114006833	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114006834	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006835	TPR motif; other site
1198114006836	binding surface
1198114006837	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114006838	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006839	binding surface
1198114006840	TPR motif; other site
1198114006841	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114006842	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006843	TPR motif; other site
1198114006844	binding surface
1198114006845	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1198114006846	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1198114006847	cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030
1198114006848	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1198114006849	DXD motif; other site
1198114006850	PilZ domain; Region: PilZ; pfam07238
1198114006851	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
1198114006852	cellulose synthase operon protein YhjQ; Region: cellulose_yhjQ; TIGR03371
1198114006853	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1198114006854	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1198114006855	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1198114006856	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
1198114006857	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1198114006858	putative ribose interaction site [chemical binding]; other site
1198114006859	putative ADP binding site [chemical binding]; other site
1198114006860	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1198114006861	active site
1198114006862	nucleotide binding site [chemical binding]; other site
1198114006863	HIGH motif; other site
1198114006864	KMSKS motif; other site
1198114006865	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1198114006866	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114006867	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1198114006868	putative active site [active]
1198114006869	Protein of unknown function (DUF4254); Region: DUF4254; pfam14063
1198114006870	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1198114006871	binding surface
1198114006872	TPR motif; other site
1198114006873	epoxyqueuosine reductase; Region: TIGR00276
1198114006874	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1198114006875	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1198114006876	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1198114006877	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1198114006878	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1198114006879	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1198114006880	NAD binding site [chemical binding]; other site
1198114006881	substrate binding site [chemical binding]; other site
1198114006882	putative active site [active]
1198114006883	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1198114006884	metal-binding site [ion binding]
1198114006885	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1198114006886	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1198114006887	metal-binding site [ion binding]
1198114006888	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1198114006889	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1198114006890	ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only]; Region: COG1606
1198114006891	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_I; cd01990
1198114006892	Ligand Binding Site [chemical binding]; other site
1198114006893	Protein of unknown function DUF111; Region: DUF111; pfam01969
1198114006894	NCAIR mutase (PurE)-related proteins [General function prediction only]; Region: COG1691
1198114006895	AIR carboxylase; Region: AIRC; smart01001
1198114006896	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
1198114006897	putative ligand binding site [chemical binding]; other site
1198114006898	gluconate 5-dehydrogenase; Provisional; Region: PRK08213
1198114006899	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1198114006900	NADP binding site [chemical binding]; other site
1198114006901	homodimer interface [polypeptide binding]; other site
1198114006902	active site
1198114006903	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1198114006904	ATP-binding site [chemical binding]; other site
1198114006905	Gluconate-6-phosphate binding site [chemical binding]; other site
1198114006906	Shikimate kinase; Region: SKI; pfam01202
1198114006907	Domain of unknown function (DUF2088); Region: DUF2088; cl15406
1198114006908	nickel-responsive transcriptional regulator NikR; Region: nikR; TIGR02793
1198114006909	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1198114006910	glucuronate isomerase; Reviewed; Region: PRK02925
1198114006911	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1198114006912	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
1198114006913	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1198114006914	active site
1198114006915	Bacterial protein of unknown function (DUF937); Region: DUF937; pfam06078
1198114006916	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1198114006917	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1198114006918	active site
1198114006919	dimer interface [polypeptide binding]; other site
1198114006920	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u1; cd11493
1198114006921	Na binding site [ion binding]; other site
1198114006922	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1198114006923	Beta-lactamase; Region: Beta-lactamase; pfam00144
1198114006924	Protein of unknown function (DUF1343); Region: DUF1343; cl01598
1198114006925	Protein of unknown function (DUF1343); Region: DUF1343; cl01598
1198114006926	PhoU domain; Region: PhoU; pfam01895
1198114006927	PhoU domain; Region: PhoU; pfam01895
1198114006928	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1198114006929	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1198114006930	active site
1198114006931	Zn binding site [ion binding]; other site
1198114006932	DinB superfamily; Region: DinB_2; pfam12867
1198114006933	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114006934	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114006935	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114006936	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1198114006937	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1198114006938	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1198114006939	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
1198114006940	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1198114006941	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1198114006942	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114006943	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114006944	catalytic residue [active]
1198114006945	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006946	binding surface
1198114006947	TPR motif; other site
1198114006948	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114006949	binding surface
1198114006950	TPR repeat; Region: TPR_11; pfam13414
1198114006951	TPR motif; other site
1198114006952	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114006953	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1198114006954	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1198114006955	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1198114006956	PAS domain; Region: PAS_9; pfam13426
1198114006957	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114006958	putative active site [active]
1198114006959	heme pocket [chemical binding]; other site
1198114006960	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114006961	dimer interface [polypeptide binding]; other site
1198114006962	phosphorylation site [posttranslational modification]
1198114006963	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114006964	ATP binding site [chemical binding]; other site
1198114006965	Mg2+ binding site [ion binding]; other site
1198114006966	G-X-G motif; other site
1198114006967	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
1198114006968	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1198114006969	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1198114006970	active site
1198114006971	SAM binding site [chemical binding]; other site
1198114006972	homodimer interface [polypeptide binding]; other site
1198114006973	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1198114006974	trimer interface [polypeptide binding]; other site
1198114006975	putative Zn binding site [ion binding]; other site
1198114006976	Biopterin-dependent aromatic amino acid hydroxylase; a family of non-heme, iron(II)-dependent enzymes that includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH), eukaryotic tyrosine hydroxylase (TyrOH) and eukaryotic tryptophan...; Region: arom_aa_hydroxylase; cd00361
1198114006977	cofactor binding site; other site
1198114006978	metal binding site [ion binding]; metal-binding site
1198114006979	putative sialic acid transporter; Region: 2A0112; TIGR00891
1198114006980	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114006981	putative substrate translocation pore; other site
1198114006982	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1198114006983	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114006984	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1198114006985	active site
1198114006986	phosphorylation site [posttranslational modification]
1198114006987	intermolecular recognition site; other site
1198114006988	dimerization interface [polypeptide binding]; other site
1198114006989	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114006990	DNA binding residues [nucleotide binding]
1198114006991	dimerization interface [polypeptide binding]; other site
1198114006992	PilZ domain; Region: PilZ; pfam07238
1198114006993	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1198114006994	carboxylate-amine ligase; Provisional; Region: PRK13515
1198114006995	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1198114006996	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1198114006997	Protein export membrane protein; Region: SecD_SecF; cl14618
1198114006998	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114006999	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114007000	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114007001	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114007002	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1198114007003	putative substrate translocation pore; other site
1198114007004	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12858
1198114007005	GMP synthase; Reviewed; Region: guaA; PRK00074
1198114007006	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1198114007007	AMP/PPi binding site [chemical binding]; other site
1198114007008	candidate oxyanion hole; other site
1198114007009	catalytic triad [active]
1198114007010	potential glutamine specificity residues [chemical binding]; other site
1198114007011	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1198114007012	ATP Binding subdomain [chemical binding]; other site
1198114007013	Ligand Binding sites [chemical binding]; other site
1198114007014	Dimerization subdomain; other site
1198114007015	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1198114007016	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1198114007017	HIGH motif; other site
1198114007018	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1198114007019	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1198114007020	active site
1198114007021	KMSKS motif; other site
1198114007022	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1198114007023	tRNA binding surface [nucleotide binding]; other site
1198114007024	sugar 1,4-lactone oxidases; Region: FAD_lactone_ox; TIGR01678
1198114007025	FAD binding domain; Region: FAD_binding_4; pfam01565
1198114007026	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
1198114007027	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
1198114007028	endonuclease IV; Provisional; Region: PRK01060
1198114007029	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1198114007030	AP (apurinic/apyrimidinic) site pocket; other site
1198114007031	DNA interaction; other site
1198114007032	Metal-binding active site; metal-binding site
1198114007033	FAD binding domain; Region: FAD_binding_1; pfam00667
1198114007034	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1198114007035	FAD binding pocket [chemical binding]; other site
1198114007036	FAD binding motif [chemical binding]; other site
1198114007037	catalytic residues [active]
1198114007038	NAD binding pocket [chemical binding]; other site
1198114007039	phosphate binding motif [ion binding]; other site
1198114007040	beta-alpha-beta structure motif; other site
1198114007041	amino acid transporter; Region: 2A0306; TIGR00909
1198114007042	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
1198114007043	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1198114007044	Ku protein, prokaryotic; Region: Ku_bact; TIGR02772
1198114007045	Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku...; Region: KU_like; cd00789
1198114007046	putative DNA binding site [nucleotide binding]; other site
1198114007047	putative homodimer interface [polypeptide binding]; other site
1198114007048	ATP-dependent DNA ligase; Reviewed; Region: ligD; PRK05972
1198114007049	DNA ligase D, 3'-phosphoesterase domain; Region: LigD_PE_dom; TIGR02777
1198114007050	Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906
1198114007051	active site
1198114007052	DNA binding site [nucleotide binding]
1198114007053	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971
1198114007054	DNA binding site [nucleotide binding]
1198114007055	PaeLigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for...; Region: PaeLigD_Pol_like; cd04862
1198114007056	nucleotide binding site [chemical binding]; other site
1198114007057	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1198114007058	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1198114007059	RNA/DNA hybrid binding site [nucleotide binding]; other site
1198114007060	active site
1198114007061	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1198114007062	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1198114007063	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1198114007064	RimM N-terminal domain; Region: RimM; pfam01782
1198114007065	PRC-barrel domain; Region: PRC; pfam05239
1198114007066	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114007067	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cd02409
1198114007068	G-X-X-G motif; other site
1198114007069	Ribosomal protein S16; Region: Ribosomal_S16; cl00368
1198114007070	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1198114007071	Putative esterase; Region: Esterase; pfam00756
1198114007072	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4947
1198114007073	Putative esterase; Region: Esterase; pfam00756
1198114007074	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1198114007075	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1198114007076	polyphosphate kinase 1; Region: poly_P_kin; TIGR03705
1198114007077	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1198114007078	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1198114007079	putative active site [active]
1198114007080	catalytic site [active]
1198114007081	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1198114007082	putative domain interface [polypeptide binding]; other site
1198114007083	putative active site [active]
1198114007084	catalytic site [active]
1198114007085	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114007086	peptidase domain interface [polypeptide binding]; other site
1198114007087	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1198114007088	catalytic residues [active]
1198114007089	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1198114007090	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1198114007091	active site
1198114007092	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
1198114007093	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1198114007094	dimer interface [polypeptide binding]; other site
1198114007095	active site
1198114007096	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1198114007097	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1198114007098	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1198114007099	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1198114007100	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1198114007101	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1198114007102	substrate binding site [chemical binding]; other site
1198114007103	oxyanion hole (OAH) forming residues; other site
1198114007104	trimer interface [polypeptide binding]; other site
1198114007105	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1198114007106	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1198114007107	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1198114007108	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1198114007109	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1198114007110	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114007111	putative active site [active]
1198114007112	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
1198114007113	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1198114007114	Substrate binding site; other site
1198114007115	Mg++ binding site; other site
1198114007116	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1198114007117	active site
1198114007118	substrate binding site [chemical binding]; other site
1198114007119	CoA binding site [chemical binding]; other site
1198114007120	Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]; Region: COG3437
1198114007121	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114007122	active site
1198114007123	phosphorylation site [posttranslational modification]
1198114007124	intermolecular recognition site; other site
1198114007125	dimerization interface [polypeptide binding]; other site
1198114007126	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1198114007127	Zn2+ binding site [ion binding]; other site
1198114007128	Mg2+ binding site [ion binding]; other site
1198114007129	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH; cd00488
1198114007130	aromatic arch; other site
1198114007131	DCoH dimer interaction site [polypeptide binding]; other site
1198114007132	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
1198114007133	DCoH tetramer interaction site [polypeptide binding]; other site
1198114007134	substrate binding site [chemical binding]; other site
1198114007135	Protein of unknown function with PCYCGC motif; Region: PCYCGC; pfam13798
1198114007136	Predicted membrane protein [Function unknown]; Region: COG2510
1198114007137	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1198114007138	active site
1198114007139	oxyanion hole [active]
1198114007140	Y-family of DNA polymerases; Region: PolY; cl12025
1198114007141	Beta-propeller repeat; Region: SBBP; pfam06739
1198114007142	Beta-propeller repeat; Region: SBBP; pfam06739
1198114007143	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
1198114007144	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1198114007145	putative active site [active]
1198114007146	catalytic triad [active]
1198114007147	putative dimer interface [polypeptide binding]; other site
1198114007148	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
1198114007149	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
1198114007150	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1198114007151	interchain domain interface [polypeptide binding]; other site
1198114007152	intrachain domain interface; other site
1198114007153	heme bH binding site [chemical binding]; other site
1198114007154	Qi binding site; other site
1198114007155	heme bL binding site [chemical binding]; other site
1198114007156	Qo binding site; other site
1198114007157	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1198114007158	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
1198114007159	iron-sulfur cluster [ion binding]; other site
1198114007160	[2Fe-2S] cluster binding site [ion binding]; other site
1198114007161	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1198114007162	Cytochrome c; Region: Cytochrom_C; pfam00034
1198114007163	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1198114007164	Cytochrome c oxidase subunit IV; Region: Cyt_c_ox_IV; pfam12270
1198114007165	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386
1198114007166	Subunit I/III interface [polypeptide binding]; other site
1198114007167	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1198114007168	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1198114007169	D-pathway; other site
1198114007170	Putative ubiquinol binding site [chemical binding]; other site
1198114007171	Low-spin heme (heme b) binding site [chemical binding]; other site
1198114007172	Putative water exit pathway; other site
1198114007173	Binuclear center (heme o3/CuB) [ion binding]; other site
1198114007174	K-pathway; other site
1198114007175	Putative proton exit pathway; other site
1198114007176	cytochrome c oxidase, subunit II; Region: CoxB; TIGR02866
1198114007177	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1198114007178	Cytochrome c; Region: Cytochrom_C; pfam00034
1198114007179	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1198114007180	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114007181	non-specific DNA binding site [nucleotide binding]; other site
1198114007182	salt bridge; other site
1198114007183	sequence-specific DNA binding site [nucleotide binding]; other site
1198114007184	HprK-related kinase A; Region: HprK_rel_A; TIGR04352
1198114007185	NHL repeat; Region: NHL; pfam01436
1198114007186	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
1198114007187	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1198114007188	NHL repeat; Region: NHL; pfam01436
1198114007189	NHL repeat; Region: NHL; pfam01436
1198114007190	NHL repeat; Region: NHL; pfam01436
1198114007191	NHL repeat; Region: NHL; pfam01436
1198114007192	NHL repeat; Region: NHL; pfam01436
1198114007193	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1198114007194	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1198114007195	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1198114007196	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1198114007197	Streptogramin lyase [Defense mechanisms]; Region: Vgb; COG4257
1198114007198	NHL repeat; Region: NHL; pfam01436
1198114007199	NHL repeat; Region: NHL; pfam01436
1198114007200	NHL repeat; Region: NHL; pfam01436
1198114007201	NHL repeat; Region: NHL; pfam01436
1198114007202	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114007203	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114007204	DNA binding site [nucleotide binding]
1198114007205	FOG: WD40 repeat [General function prediction only]; Region: COG2319
1198114007206	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
1198114007207	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1198114007208	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114007209	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1198114007210	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1198114007211	TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA...; Region: TlpA_like_DipZ_like; cd03012
1198114007212	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114007213	catalytic residues [active]
1198114007214	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1198114007215	SelR domain; Region: SelR; pfam01641
1198114007216	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1198114007217	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1198114007218	iron-sulfur cluster [ion binding]; other site
1198114007219	[2Fe-2S] cluster binding site [ion binding]; other site
1198114007220	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1198114007221	hydrophobic ligand binding site; other site
1198114007222	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1198114007223	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
1198114007224	putative Cl- selectivity filter; other site
1198114007225	putative pore gating glutamate residue; other site
1198114007226	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1198114007227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114007228	putative substrate translocation pore; other site
1198114007229	L-fucose transporter; Provisional; Region: PRK10133; cl17665
1198114007230	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1198114007231	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1198114007232	dimer interface [polypeptide binding]; other site
1198114007233	active site
1198114007234	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1198114007235	dimer interface [polypeptide binding]; other site
1198114007236	active site
1198114007237	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1198114007238	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
1198114007239	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1198114007240	4Fe-4S binding domain; Region: Fer4; cl02805
1198114007241	Cysteine-rich domain; Region: CCG; pfam02754
1198114007242	Cysteine-rich domain; Region: CCG; pfam02754
1198114007243	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1198114007244	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1198114007245	Ligand Binding Site [chemical binding]; other site
1198114007246	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1198114007247	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1198114007248	Ligand binding site [chemical binding]; other site
1198114007249	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1198114007250	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08217
1198114007251	17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs; Region: HSD10-like_SDR_c; cd05371
1198114007252	NAD binding site [chemical binding]; other site
1198114007253	homodimer interface [polypeptide binding]; other site
1198114007254	homotetramer interface [polypeptide binding]; other site
1198114007255	active site
1198114007256	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1198114007257	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1198114007258	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
1198114007259	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1198114007260	oxalacetate binding site [chemical binding]; other site
1198114007261	citrylCoA binding site [chemical binding]; other site
1198114007262	coenzyme A binding site [chemical binding]; other site
1198114007263	catalytic triad [active]
1198114007264	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1198114007265	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1198114007266	tetramer interface [polypeptide binding]; other site
1198114007267	active site
1198114007268	Mg2+/Mn2+ binding site [ion binding]; other site
1198114007269	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114007270	metabolite-proton symporter; Region: 2A0106; TIGR00883
1198114007271	putative substrate translocation pore; other site
1198114007272	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1198114007273	thiS-thiF/thiG interaction site; other site
1198114007274	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1198114007275	substrate binding site [chemical binding]; other site
1198114007276	dimer interface [polypeptide binding]; other site
1198114007277	ATP binding site [chemical binding]; other site
1198114007278	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1198114007279	active site
1198114007280	dimer interface [polypeptide binding]; other site
1198114007281	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
1198114007282	Amidinotransferase; Region: Amidinotransf; cl12043
1198114007283	CAAX protease self-immunity; Region: Abi; pfam02517
1198114007284	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1198114007285	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114007286	putative active site [active]
1198114007287	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1198114007288	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1198114007289	active site
1198114007290	PHP Thumb interface [polypeptide binding]; other site
1198114007291	metal binding site [ion binding]; metal-binding site
1198114007292	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1198114007293	generic binding surface I; other site
1198114007294	generic binding surface II; other site
1198114007295	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
1198114007296	putative active site [active]
1198114007297	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1198114007298	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
1198114007299	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114007300	metal binding site [ion binding]; metal-binding site
1198114007301	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1198114007302	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114007303	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1198114007304	nucleophilic elbow; other site
1198114007305	catalytic triad; other site
1198114007306	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1198114007307	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114007308	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114007309	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114007310	putative active site [active]
1198114007311	heme pocket [chemical binding]; other site
1198114007312	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114007313	dimer interface [polypeptide binding]; other site
1198114007314	phosphorylation site [posttranslational modification]
1198114007315	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114007316	ATP binding site [chemical binding]; other site
1198114007317	Mg2+ binding site [ion binding]; other site
1198114007318	G-X-G motif; other site
1198114007319	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114007320	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114007321	active site
1198114007322	phosphorylation site [posttranslational modification]
1198114007323	intermolecular recognition site; other site
1198114007324	dimerization interface [polypeptide binding]; other site
1198114007325	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114007326	Walker A motif; other site
1198114007327	ATP binding site [chemical binding]; other site
1198114007328	Walker B motif; other site
1198114007329	arginine finger; other site
1198114007330	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114007331	TIR domain; Region: TIR_2; cl17458
1198114007332	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114007333	Uncharacterized conserved protein [Function unknown]; Region: COG1262
1198114007334	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1198114007335	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
1198114007336	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1198114007337	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
1198114007338	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1198114007339	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114007340	NAD(P) binding site [chemical binding]; other site
1198114007341	active site
1198114007342	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114007343	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114007344	Amidohydrolase; Region: Amidohydro_4; pfam13147
1198114007345	active site
1198114007346	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1198114007347	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114007348	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114007349	NAD(P) binding site [chemical binding]; other site
1198114007350	active site
1198114007351	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1198114007352	putative chaperone; Provisional; Region: PRK11678
1198114007353	nucleotide binding site [chemical binding]; other site
1198114007354	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1198114007355	SBD interface [polypeptide binding]; other site
1198114007356	Domain of unknown function (DUF336); Region: DUF336; cl01249
1198114007357	Protein of unknown function (DUF3738); Region: DUF3738; cl11887
1198114007358	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1198114007359	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
1198114007360	domain interfaces; other site
1198114007361	active site
1198114007362	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1198114007363	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114007364	S-adenosylmethionine binding site [chemical binding]; other site
1198114007365	Predicted methyltransferase regulatory domain; Region: MethyTransf_Reg; pfam10119
1198114007366	UPF0126 domain; Region: UPF0126; pfam03458
1198114007367	Predicted membrane protein [Function unknown]; Region: COG2860
1198114007368	UPF0126 domain; Region: UPF0126; pfam03458
1198114007369	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1198114007370	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1198114007371	HflX GTPase family; Region: HflX; cd01878
1198114007372	G1 box; other site
1198114007373	GTP/Mg2+ binding site [chemical binding]; other site
1198114007374	Switch I region; other site
1198114007375	G2 box; other site
1198114007376	G3 box; other site
1198114007377	Switch II region; other site
1198114007378	G4 box; other site
1198114007379	G5 box; other site
1198114007380	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1198114007381	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1198114007382	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1198114007383	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1198114007384	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1198114007385	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1198114007386	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1198114007387	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1198114007388	PIN domain; Region: PIN_3; cl17397
1198114007389	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1198114007390	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1198114007391	tRNA; other site
1198114007392	putative tRNA binding site [nucleotide binding]; other site
1198114007393	putative NADP binding site [chemical binding]; other site
1198114007394	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1198114007395	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1198114007396	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
1198114007397	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1198114007398	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1198114007399	MutS domain I; Region: MutS_I; pfam01624
1198114007400	MutS domain III; Region: MutS_III; pfam05192
1198114007401	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1198114007402	Walker A/P-loop; other site
1198114007403	ATP binding site [chemical binding]; other site
1198114007404	Q-loop/lid; other site
1198114007405	ABC transporter signature motif; other site
1198114007406	Walker B; other site
1198114007407	D-loop; other site
1198114007408	H-loop/switch region; other site
1198114007409	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1198114007410	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1198114007411	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1198114007412	Cupin domain; Region: Cupin_2; cl17218
1198114007413	Transposase; Region: HTH_Tnp_1; pfam01527
1198114007414	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114007415	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114007416	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114007417	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
1198114007418	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1198114007419	active site
1198114007420	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114007421	dimer interface [polypeptide binding]; other site
1198114007422	conserved gate region; other site
1198114007423	ABC-ATPase subunit interface; other site
1198114007424	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1198114007425	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114007426	Walker A/P-loop; other site
1198114007427	ATP binding site [chemical binding]; other site
1198114007428	Q-loop/lid; other site
1198114007429	ABC transporter signature motif; other site
1198114007430	Walker B; other site
1198114007431	D-loop; other site
1198114007432	H-loop/switch region; other site
1198114007433	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1198114007434	AAA domain; Region: AAA_33; pfam13671
1198114007435	L-seryl-tRNA(Sec) kinase, eukaryotic; Region: selen_PSTK_euk; TIGR03575
1198114007436	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1198114007437	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1198114007438	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1198114007439	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154
1198114007440	homotrimer interaction site [polypeptide binding]; other site
1198114007441	putative active site [active]
1198114007442	Phosphoglycerate kinase; Region: PGK; pfam00162
1198114007443	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1198114007444	substrate binding site [chemical binding]; other site
1198114007445	hinge regions; other site
1198114007446	ADP binding site [chemical binding]; other site
1198114007447	catalytic site [active]
1198114007448	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
1198114007449	four helix bundle protein; Region: TIGR02436
1198114007450	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1198114007451	triosephosphate isomerase; Provisional; Region: PRK14565
1198114007452	substrate binding site [chemical binding]; other site
1198114007453	dimer interface [polypeptide binding]; other site
1198114007454	catalytic triad [active]
1198114007455	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
1198114007456	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1198114007457	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1198114007458	Catalytic site [active]
1198114007459	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1198114007460	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1198114007461	putative active site [active]
1198114007462	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1198114007463	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1198114007464	hinge; other site
1198114007465	active site
1198114007466	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1198114007467	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114007468	Coenzyme A binding pocket [chemical binding]; other site
1198114007469	putative menaquinone biosynthesis protein, SCO4494 family; Region: mena_SCO4494; TIGR03700
1198114007470	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
1198114007471	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1198114007472	ligand binding site [chemical binding]; other site
1198114007473	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1198114007474	[Protein-PII] uridylyltransferase; Region: UTase_glnD; TIGR01693
1198114007475	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1198114007476	metal binding triad; other site
1198114007477	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1198114007478	HD domain; Region: HD; pfam01966
1198114007479	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1198114007480	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1198114007481	Nitrogen regulatory protein P-II; Region: P-II; pfam00543
1198114007482	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1198114007483	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1198114007484	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1198114007485	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1198114007486	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1198114007487	TM-ABC transporter signature motif; other site
1198114007488	Predicted membrane protein [Function unknown]; Region: COG2246
1198114007489	GtrA-like protein; Region: GtrA; pfam04138
1198114007490	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1198114007491	dimer interface [polypeptide binding]; other site
1198114007492	active site
1198114007493	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1198114007494	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1198114007495	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1198114007496	active site
1198114007497	catalytic site [active]
1198114007498	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1198114007499	RNA binding site [nucleotide binding]; other site
1198114007500	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1198114007501	RNA binding site [nucleotide binding]; other site
1198114007502	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1198114007503	RNA binding site [nucleotide binding]; other site
1198114007504	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1198114007505	RNA binding site [nucleotide binding]; other site
1198114007506	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1198114007507	RNA binding site [nucleotide binding]; other site
1198114007508	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114007509	FtsX-like permease family; Region: FtsX; pfam02687
1198114007510	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1198114007511	oligomeric interface; other site
1198114007512	putative active site [active]
1198114007513	homodimer interface [polypeptide binding]; other site
1198114007514	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114007515	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114007516	Walker A/P-loop; other site
1198114007517	ATP binding site [chemical binding]; other site
1198114007518	Q-loop/lid; other site
1198114007519	ABC transporter signature motif; other site
1198114007520	Walker B; other site
1198114007521	D-loop; other site
1198114007522	H-loop/switch region; other site
1198114007523	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1198114007524	active site
1198114007525	catalytic triad [active]
1198114007526	oxyanion hole [active]
1198114007527	switch loop; other site
1198114007528	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01851
1198114007529	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1198114007530	RNA binding site [nucleotide binding]; other site
1198114007531	active site
1198114007532	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1198114007533	GTP cyclohydrolase I; Provisional; Region: PLN03044
1198114007534	homodecamer interface [polypeptide binding]; other site
1198114007535	active site
1198114007536	putative catalytic site residues [active]
1198114007537	zinc binding site [ion binding]; other site
1198114007538	GTP-CH-I/GFRP interaction surface; other site
1198114007539	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1198114007540	active site
1198114007541	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1198114007542	active site
1198114007543	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114007544	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114007545	active site
1198114007546	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1198114007547	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114007548	catalytic residues [active]
1198114007549	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1198114007550	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1198114007551	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1198114007552	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007553	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114007554	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007555	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114007556	Iron permease FTR1 family; Region: FTR1; cl00475
1198114007557	Predicted membrane protein (DUF2318); Region: DUF2318; pfam10080
1198114007558	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114007559	FtsX-like permease family; Region: FtsX; pfam02687
1198114007560	FtsX-like permease family; Region: FtsX; pfam02687
1198114007561	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1198114007562	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1198114007563	Walker A/P-loop; other site
1198114007564	ATP binding site [chemical binding]; other site
1198114007565	Q-loop/lid; other site
1198114007566	ABC transporter signature motif; other site
1198114007567	Walker B; other site
1198114007568	D-loop; other site
1198114007569	H-loop/switch region; other site
1198114007570	Flagellin N-methylase; Region: FliB; pfam03692
1198114007571	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114007572	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1198114007573	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114007574	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1198114007575	dimerization interface [polypeptide binding]; other site
1198114007576	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007577	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1198114007578	catalytic residues [active]
1198114007579	dimer interface [polypeptide binding]; other site
1198114007580	allophanate hydrolase; Provisional; Region: PRK08186
1198114007581	Amidase; Region: Amidase; pfam01425
1198114007582	SnoaL-like domain; Region: SnoaL_4; pfam13577
1198114007583	urea carboxylase; Region: urea_carbox; TIGR02712
1198114007584	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1198114007585	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1198114007586	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
1198114007587	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1198114007588	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1198114007589	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1198114007590	carboxyltransferase (CT) interaction site; other site
1198114007591	biotinylation site [posttranslational modification]; other site
1198114007592	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1198114007593	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1198114007594	urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425
1198114007595	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1198114007596	Streptogramin lyase [Defense mechanisms]; Region: Vgb; COG4257
1198114007597	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1198114007598	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
1198114007599	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114007600	dimer interface [polypeptide binding]; other site
1198114007601	putative PBP binding loops; other site
1198114007602	ABC-ATPase subunit interface; other site
1198114007603	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1198114007604	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1198114007605	Walker A/P-loop; other site
1198114007606	ATP binding site [chemical binding]; other site
1198114007607	Q-loop/lid; other site
1198114007608	ABC transporter signature motif; other site
1198114007609	Walker B; other site
1198114007610	D-loop; other site
1198114007611	H-loop/switch region; other site
1198114007612	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
1198114007613	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
1198114007614	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
1198114007615	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
1198114007616	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
1198114007617	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1198114007618	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1198114007619	N-terminal plug; other site
1198114007620	ligand-binding site [chemical binding]; other site
1198114007621	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1198114007622	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114007623	FAD binding domain; Region: FAD_binding_4; pfam01565
1198114007624	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
1198114007625	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1198114007626	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114007627	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1198114007628	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1198114007629	RNase E interface [polypeptide binding]; other site
1198114007630	trimer interface [polypeptide binding]; other site
1198114007631	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1198114007632	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1198114007633	RNase E interface [polypeptide binding]; other site
1198114007634	trimer interface [polypeptide binding]; other site
1198114007635	active site
1198114007636	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1198114007637	putative nucleic acid binding region [nucleotide binding]; other site
1198114007638	G-X-X-G motif; other site
1198114007639	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1198114007640	RNA binding site [nucleotide binding]; other site
1198114007641	domain interface; other site
1198114007642	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1198114007643	16S/18S rRNA binding site [nucleotide binding]; other site
1198114007644	S13e-L30e interaction site [polypeptide binding]; other site
1198114007645	25S rRNA binding site [nucleotide binding]; other site
1198114007646	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1198114007647	flagellar hook-associated protein 3; Region: flagell_flgL; TIGR02550
1198114007648	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1198114007649	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1198114007650	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
1198114007651	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1198114007652	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1198114007653	Flagellar L-ring protein; Region: FlgH; cl17277
1198114007654	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1198114007655	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1198114007656	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1198114007657	flagellar hook-basal body protein; Region: FlgEFG_subfam; TIGR03506
1198114007658	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1198114007659	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114007660	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114007661	active site
1198114007662	phosphorylation site [posttranslational modification]
1198114007663	intermolecular recognition site; other site
1198114007664	dimerization interface [polypeptide binding]; other site
1198114007665	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1198114007666	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1198114007667	hinge; other site
1198114007668	active site
1198114007669	Bifunctional nuclease; Region: DNase-RNase; pfam02577
1198114007670	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1198114007671	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1198114007672	TRAM domain; Region: TRAM; pfam01938
1198114007673	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1198114007674	Histidine kinase; Region: His_kinase; pfam06580
1198114007675	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114007676	ATP binding site [chemical binding]; other site
1198114007677	Mg2+ binding site [ion binding]; other site
1198114007678	G-X-G motif; other site
1198114007679	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1198114007680	dimerization interface [polypeptide binding]; other site
1198114007681	active site
1198114007682	DinB superfamily; Region: DinB_2; pfam12867
1198114007683	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1198114007684	Phage minor tail protein; Region: Phage_min_tail; cl01940
1198114007685	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1198114007686	catalytic residues [active]
1198114007687	dimer interface [polypeptide binding]; other site
1198114007688	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1198114007689	B12 binding site [chemical binding]; other site
1198114007690	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1198114007691	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1198114007692	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1198114007693	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
1198114007694	Leucine carboxyl methyltransferase; Region: LCM; cl01306
1198114007695	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
1198114007696	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1198114007697	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1198114007698	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1198114007699	RNA binding surface [nucleotide binding]; other site
1198114007700	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1198114007701	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1198114007702	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114007703	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114007704	DNA binding residues [nucleotide binding]
1198114007705	putative anti-sigmaE protein; Provisional; Region: PRK13920
1198114007706	Anti-sigma-K factor rskA; Region: RskA; pfam10099
1198114007707	Integral membrane protein DUF92; Region: DUF92; pfam01940
1198114007708	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1198114007709	putative active site [active]
1198114007710	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1198114007711	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1198114007712	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1198114007713	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1198114007714	recombination factor protein RarA; Reviewed; Region: PRK13342
1198114007715	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114007716	Walker A motif; other site
1198114007717	ATP binding site [chemical binding]; other site
1198114007718	Walker B motif; other site
1198114007719	arginine finger; other site
1198114007720	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1198114007721	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
1198114007722	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1198114007723	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1198114007724	DsbD alpha interface [polypeptide binding]; other site
1198114007725	catalytic residues [active]
1198114007726	CoA binding domain; Region: CoA_binding; cl17356
1198114007727	DinB superfamily; Region: DinB_2; pfam12867
1198114007728	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1198114007729	PCRF domain; Region: PCRF; pfam03462
1198114007730	RF-1 domain; Region: RF-1; pfam00472
1198114007731	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1198114007732	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1198114007733	putative active site [active]
1198114007734	catalytic triad [active]
1198114007735	putative dimer interface [polypeptide binding]; other site
1198114007736	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1198114007737	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1198114007738	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1198114007739	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1198114007740	homodimer interface [polypeptide binding]; other site
1198114007741	metal binding site [ion binding]; metal-binding site
1198114007742	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1198114007743	homodimer interface [polypeptide binding]; other site
1198114007744	active site
1198114007745	putative chemical substrate binding site [chemical binding]; other site
1198114007746	metal binding site [ion binding]; metal-binding site
1198114007747	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1198114007748	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1198114007749	ligand binding site [chemical binding]; other site
1198114007750	excinuclease ABC subunit C; Provisional; Region: uvrC; PRK14669
1198114007751	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1198114007752	GIY-YIG motif/motif A; other site
1198114007753	active site
1198114007754	catalytic site [active]
1198114007755	putative DNA binding site [nucleotide binding]; other site
1198114007756	metal binding site [ion binding]; metal-binding site
1198114007757	UvrB/uvrC motif; Region: UVR; pfam02151
1198114007758	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1198114007759	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1198114007760	Protein of unknown function (DUF3455); Region: DUF3455; pfam11937
1198114007761	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1198114007762	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1198114007763	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1198114007764	S-adenosylmethionine binding site [chemical binding]; other site
1198114007765	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1198114007766	active site
1198114007767	putative DNA-binding cleft [nucleotide binding]; other site
1198114007768	dimer interface [polypeptide binding]; other site
1198114007769	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1198114007770	ThiS interaction site; other site
1198114007771	putative active site [active]
1198114007772	tetramer interface [polypeptide binding]; other site
1198114007773	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
1198114007774	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1198114007775	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1198114007776	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1198114007777	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1198114007778	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1198114007779	NADH:ubiquinone oxidoreductase 27 kD subunit [Energy production and conversion]; Region: NuoC; COG0852
1198114007780	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
1198114007781	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1198114007782	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1198114007783	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
1198114007784	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1198114007785	putative dimer interface [polypeptide binding]; other site
1198114007786	[2Fe-2S] cluster binding site [ion binding]; other site
1198114007787	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
1198114007788	SLBB domain; Region: SLBB; pfam10531
1198114007789	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
1198114007790	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1198114007791	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1198114007792	catalytic loop [active]
1198114007793	iron binding site [ion binding]; other site
1198114007794	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1198114007795	4Fe-4S binding domain; Region: Fer4; pfam00037
1198114007796	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1198114007797	molybdopterin cofactor binding site; other site
1198114007798	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1198114007799	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1198114007800	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1198114007801	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1198114007802	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1198114007803	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1198114007804	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1198114007805	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1198114007806	NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; Region: NuoM; COG1008
1198114007807	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1198114007808	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1198114007809	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1198114007810	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114007811	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114007812	ligand binding site [chemical binding]; other site
1198114007813	flexible hinge region; other site
1198114007814	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1198114007815	non-specific DNA interactions [nucleotide binding]; other site
1198114007816	DNA binding site [nucleotide binding]
1198114007817	sequence specific DNA binding site [nucleotide binding]; other site
1198114007818	putative cAMP binding site [chemical binding]; other site
1198114007819	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1198114007820	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1198114007821	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1198114007822	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1198114007823	dimer interface [polypeptide binding]; other site
1198114007824	putative anticodon binding site; other site
1198114007825	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1198114007826	motif 1; other site
1198114007827	active site
1198114007828	motif 2; other site
1198114007829	motif 3; other site
1198114007830	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
1198114007831	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1198114007832	putative active site [active]
1198114007833	metal binding site [ion binding]; metal-binding site
1198114007834	homodimer binding site [polypeptide binding]; other site
1198114007835	Transcriptional regulator; Region: Rrf2; pfam02082
1198114007836	Predicted transcriptional regulator [Transcription]; Region: COG1959
1198114007837	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
1198114007838	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1198114007839	Walker A/P-loop; other site
1198114007840	ATP binding site [chemical binding]; other site
1198114007841	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1198114007842	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1198114007843	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1198114007844	ABC transporter signature motif; other site
1198114007845	Walker B; other site
1198114007846	D-loop; other site
1198114007847	H-loop/switch region; other site
1198114007848	short chain dehydrogenase; Provisional; Region: PRK06500
1198114007849	classical (c) SDRs; Region: SDR_c; cd05233
1198114007850	NAD(P) binding site [chemical binding]; other site
1198114007851	active site
1198114007852	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
1198114007853	active site
1198114007854	ATP binding site [chemical binding]; other site
1198114007855	substrate binding site [chemical binding]; other site
1198114007856	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1198114007857	Colicin V production protein; Region: Colicin_V; pfam02674
1198114007858	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114007859	TPR repeat; Region: TPR_11; pfam13414
1198114007860	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1198114007861	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FkbH; COG3882
1198114007862	HAD-superfamily phosphatase, subfamily IIIC; Region: HAD-SF-IIIC; TIGR01681
1198114007863	Domain of unknown function (DUF2088); Region: DUF2088; cl15406
1198114007864	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
1198114007865	Chloramphenicol acetyltransferase; Region: CAT; cl02008
1198114007866	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1198114007867	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114007868	dimer interface [polypeptide binding]; other site
1198114007869	phosphorylation site [posttranslational modification]
1198114007870	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114007871	ATP binding site [chemical binding]; other site
1198114007872	Mg2+ binding site [ion binding]; other site
1198114007873	G-X-G motif; other site
1198114007874	Middle domain of rhamnogalacturonan lyase, a family 4 polysaccharide lyase; Region: RGL4_M; cd10316
1198114007875	K+-transporting ATPase, c chain [Inorganic ion transport and metabolism]; Region: KdpC; COG2156
1198114007876	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1198114007877	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1198114007878	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1198114007879	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1198114007880	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114007881	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114007882	active site
1198114007883	phosphorylation site [posttranslational modification]
1198114007884	intermolecular recognition site; other site
1198114007885	dimerization interface [polypeptide binding]; other site
1198114007886	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114007887	DNA binding site [nucleotide binding]
1198114007888	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1198114007889	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114007890	dimer interface [polypeptide binding]; other site
1198114007891	phosphorylation site [posttranslational modification]
1198114007892	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114007893	ATP binding site [chemical binding]; other site
1198114007894	Mg2+ binding site [ion binding]; other site
1198114007895	G-X-G motif; other site
1198114007896	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
1198114007897	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1198114007898	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114007899	active site
1198114007900	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114007901	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114007902	active site
1198114007903	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
1198114007904	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
1198114007905	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
1198114007906	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
1198114007907	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
1198114007908	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
1198114007909	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
1198114007910	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1198114007911	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
1198114007912	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
1198114007913	ATPase family associated with various cellular activities (AAA); Region: AAA; pfam00004
1198114007914	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
1198114007915	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
1198114007916	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114007917	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1198114007918	Walker A motif; other site
1198114007919	ATP binding site [chemical binding]; other site
1198114007920	Walker B motif; other site
1198114007921	arginine finger; other site
1198114007922	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1198114007923	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1198114007924	FAD binding site [chemical binding]; other site
1198114007925	homotetramer interface [polypeptide binding]; other site
1198114007926	substrate binding pocket [chemical binding]; other site
1198114007927	catalytic base [active]
1198114007928	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
1198114007929	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114007930	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1198114007931	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1198114007932	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1198114007933	active site residue [active]
1198114007934	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114007935	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1198114007936	dimer interface [polypeptide binding]; other site
1198114007937	FMN binding site [chemical binding]; other site
1198114007938	putative methyltransferase, LIC12133 family; Region: MTase_LIC12133; TIGR04325
1198114007939	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1198114007940	elongation factor P; Validated; Region: PRK00529
1198114007941	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1198114007942	RNA binding site [nucleotide binding]; other site
1198114007943	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1198114007944	RNA binding site [nucleotide binding]; other site
1198114007945	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1198114007946	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1198114007947	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1198114007948	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1198114007949	Uncharacterized protein with a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG4867
1198114007950	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114007951	metal ion-dependent adhesion site (MIDAS); other site
1198114007952	Protein of unknown function (DUF664); Region: DUF664; pfam04978
1198114007953	Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847
1198114007954	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1198114007955	dimer interface [polypeptide binding]; other site
1198114007956	ADP-ribose binding site [chemical binding]; other site
1198114007957	active site
1198114007958	nudix motif; other site
1198114007959	metal binding site [ion binding]; metal-binding site
1198114007960	Predicted acyl esterases [General function prediction only]; Region: COG2936
1198114007961	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1198114007962	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
1198114007963	Zn-finger in ubiquitin-hydrolases and other protein; Region: zf-UBP; pfam02148
1198114007964	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1198114007965	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114007966	active site
1198114007967	phosphorylation site [posttranslational modification]
1198114007968	intermolecular recognition site; other site
1198114007969	dimerization interface [polypeptide binding]; other site
1198114007970	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114007971	Walker A motif; other site
1198114007972	ATP binding site [chemical binding]; other site
1198114007973	Walker B motif; other site
1198114007974	arginine finger; other site
1198114007975	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1198114007976	ribonuclease PH; Reviewed; Region: rph; PRK00173
1198114007977	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1198114007978	hexamer interface [polypeptide binding]; other site
1198114007979	active site
1198114007980	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
1198114007981	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114007982	TPR repeat; Region: TPR_11; pfam13414
1198114007983	binding surface
1198114007984	TPR motif; other site
1198114007985	TPR repeat; Region: TPR_11; pfam13414
1198114007986	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114007987	binding surface
1198114007988	TPR motif; other site
1198114007989	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1198114007990	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1198114007991	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007992	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007993	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007994	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007995	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007996	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007997	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007998	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114007999	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114008000	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114008001	Thioredoxin; Region: Thioredoxin_4; cl17273
1198114008002	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1198114008003	Thioredoxin; Region: Thioredoxin_4; pfam13462
1198114008004	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1198114008005	Thioredoxin; Region: Thioredoxin_4; cl17273
1198114008006	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114008007	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1198114008008	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1198114008009	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114008010	dimer interface [polypeptide binding]; other site
1198114008011	phosphorylation site [posttranslational modification]
1198114008012	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114008013	ATP binding site [chemical binding]; other site
1198114008014	Mg2+ binding site [ion binding]; other site
1198114008015	G-X-G motif; other site
1198114008016	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
1198114008017	dimer interface [polypeptide binding]; other site
1198114008018	RNA polymerase factor sigma-70; Validated; Region: PRK09047
1198114008019	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114008020	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114008021	DNA binding residues [nucleotide binding]
1198114008022	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
1198114008023	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1198114008024	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1198114008025	EcsC protein family; Region: EcsC; pfam12787
1198114008026	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
1198114008027	RNB domain; Region: RNB; pfam00773
1198114008028	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114008029	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114008030	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114008031	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258
1198114008032	MOSC domain; Region: MOSC; pfam03473
1198114008033	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1198114008034	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
1198114008035	Domain of unknown function (DUF718); Region: DUF718; pfam05336
1198114008036	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1198114008037	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114008038	active site
1198114008039	DNA binding site [nucleotide binding]
1198114008040	Int/Topo IB signature motif; other site
1198114008041	Helix-turn-helix domain; Region: HTH_17; pfam12728
1198114008042	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1198114008043	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114008044	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1198114008045	dimerization interface [polypeptide binding]; other site
1198114008046	substrate binding pocket [chemical binding]; other site
1198114008047	YHS domain; Region: YHS; pfam04945
1198114008048	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1198114008049	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1198114008050	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114008051	motif II; other site
1198114008052	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1198114008053	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114008054	motif II; other site
1198114008055	putative phosphoketolase; Provisional; Region: PRK05261
1198114008056	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
1198114008057	TPP-binding site; other site
1198114008058	XFP C-terminal domain; Region: XFP_C; pfam09363
1198114008059	Class I aldolases; Region: Aldolase_Class_I; cl17187
1198114008060	catalytic residue [active]
1198114008061	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1198114008062	triosephosphate isomerase; Provisional; Region: PRK14565
1198114008063	substrate binding site [chemical binding]; other site
1198114008064	dimer interface [polypeptide binding]; other site
1198114008065	catalytic triad [active]
1198114008066	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114008067	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
1198114008068	phosphoglucomutase; Validated; Region: PRK07564
1198114008069	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1198114008070	active site
1198114008071	substrate binding site [chemical binding]; other site
1198114008072	metal binding site [ion binding]; metal-binding site
1198114008073	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
1198114008074	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1198114008075	core domain interface [polypeptide binding]; other site
1198114008076	delta subunit interface [polypeptide binding]; other site
1198114008077	epsilon subunit interface [polypeptide binding]; other site
1198114008078	alternate F1F0 ATPase, F1 subunit alpha; Region: alt_F1F0_F1_al; TIGR03324
1198114008079	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1198114008080	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1198114008081	beta subunit interaction interface [polypeptide binding]; other site
1198114008082	Walker A motif; other site
1198114008083	ATP binding site [chemical binding]; other site
1198114008084	Walker B motif; other site
1198114008085	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1198114008086	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
1198114008087	alternate F1F0 ATPase, F0 subunit B; Region: alt_F1F0_F0_B; TIGR03321
1198114008088	alternate F1F0 ATPase, F0 subunit C; Region: alt_F1F0_F0_C; TIGR03322
1198114008089	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1198114008090	alternate F1F0 ATPase, F0 subunit A; Region: altF1_A; TIGR03306
1198114008091	F1/F0 ATPase, Methanosarcina type, subunit 2; Region: F1F0_chp_2; TIGR03165
1198114008092	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; cl09754
1198114008093	F0F1 ATP synthase subunit epsilon; Validated; Region: PRK06228
1198114008094	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1198114008095	gamma subunit interface [polypeptide binding]; other site
1198114008096	epsilon subunit interface [polypeptide binding]; other site
1198114008097	LBP interface [polypeptide binding]; other site
1198114008098	alternate F1F0 ATPase, F1 subunit beta; Region: alt_F1F0_F1_bet; TIGR03305
1198114008099	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1198114008100	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1198114008101	alpha subunit interaction interface [polypeptide binding]; other site
1198114008102	Walker A motif; other site
1198114008103	ATP binding site [chemical binding]; other site
1198114008104	Walker B motif; other site
1198114008105	inhibitor binding site; inhibition site
1198114008106	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1198114008107	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114008108	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114008109	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114008110	Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Region: PulA; COG1523
1198114008111	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1198114008112	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1198114008113	active site
1198114008114	catalytic site [active]
1198114008115	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1198114008116	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_2; TIGR02822
1198114008117	NAD(P) binding site [chemical binding]; other site
1198114008118	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114008119	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114008120	ligand binding site [chemical binding]; other site
1198114008121	flexible hinge region; other site
1198114008122	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1198114008123	putative switch regulator; other site
1198114008124	non-specific DNA interactions [nucleotide binding]; other site
1198114008125	DNA binding site [nucleotide binding]
1198114008126	sequence specific DNA binding site [nucleotide binding]; other site
1198114008127	putative cAMP binding site [chemical binding]; other site
1198114008128	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1198114008129	nudix motif; other site
1198114008130	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114008131	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114008132	dimer interface [polypeptide binding]; other site
1198114008133	phosphorylation site [posttranslational modification]
1198114008134	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114008135	ATP binding site [chemical binding]; other site
1198114008136	Mg2+ binding site [ion binding]; other site
1198114008137	G-X-G motif; other site
1198114008138	circadian clock protein KaiC; Reviewed; Region: PRK09302
1198114008139	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114008140	Walker A motif; other site
1198114008141	ATP binding site [chemical binding]; other site
1198114008142	Walker B motif; other site
1198114008143	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114008144	Walker A motif; other site
1198114008145	ATP binding site [chemical binding]; other site
1198114008146	Walker B motif; other site
1198114008147	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1198114008148	ParB-like nuclease domain; Region: ParB; smart00470
1198114008149	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1198114008150	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114008151	active site
1198114008152	DNA binding site [nucleotide binding]
1198114008153	Int/Topo IB signature motif; other site
1198114008154	Winged helix-turn helix; Region: HTH_29; pfam13551
1198114008155	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1198114008156	DNA-binding interface [nucleotide binding]; DNA binding site
1198114008157	Homeodomain-like domain; Region: HTH_32; pfam13565
1198114008158	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1198114008159	Integrase core domain; Region: rve; pfam00665
1198114008160	Integrase core domain; Region: rve_3; pfam13683
1198114008161	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1198114008162	Helix-Turn-Helix DNA binding domain of the CadR- and PbrR-like transcription regulators; Region: HTH_CadR-PbrR-like; cd04785
1198114008163	DNA binding residues [nucleotide binding]
1198114008164	dimer interface [polypeptide binding]; other site
1198114008165	putative metal binding site [ion binding]; other site
1198114008166	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114008167	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
1198114008168	ligand binding site [chemical binding]; other site
1198114008169	flexible hinge region; other site
1198114008170	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1198114008171	putative switch regulator; other site
1198114008172	non-specific DNA interactions [nucleotide binding]; other site
1198114008173	DNA binding site [nucleotide binding]
1198114008174	sequence specific DNA binding site [nucleotide binding]; other site
1198114008175	putative cAMP binding site [chemical binding]; other site
1198114008176	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114008177	DNA-binding site [nucleotide binding]; DNA binding site
1198114008178	RNA-binding motif; other site
1198114008179	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114008180	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114008181	active site
1198114008182	phosphorylation site [posttranslational modification]
1198114008183	intermolecular recognition site; other site
1198114008184	dimerization interface [polypeptide binding]; other site
1198114008185	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114008186	Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504
1198114008187	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114008188	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114008189	DNA binding site [nucleotide binding]
1198114008190	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114008191	TPR motif; other site
1198114008192	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1198114008193	binding surface
1198114008194	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114008195	TPR motif; other site
1198114008196	binding surface
1198114008197	Helix-turn-helix domain; Region: HTH_18; pfam12833
1198114008198	Protein of unknown function (DUF460); Region: DUF460; pfam04312
1198114008199	Helix-turn-helix domain; Region: HTH_18; pfam12833
1198114008200	Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504
1198114008201	Helix-turn-helix domain; Region: HTH_18; pfam12833
1198114008202	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1198114008203	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114008204	active site
1198114008205	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
1198114008206	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1198114008207	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1198114008208	putative active site [active]
1198114008209	putative NTP binding site [chemical binding]; other site
1198114008210	putative nucleic acid binding site [nucleotide binding]; other site
1198114008211	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1198114008212	hypothetical protein; Provisional; Region: PRK00106
1198114008213	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1198114008214	ligand binding site [chemical binding]; other site
1198114008215	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
1198114008216	TrbC/VIRB2 family; Region: TrbC; cl01583
1198114008217	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
1198114008218	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1198114008219	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114008220	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114008221	DNA binding residues [nucleotide binding]
1198114008222	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
1198114008223	Proline dehydrogenase; Region: Pro_dh; cl03282
1198114008224	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114008225	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1198114008226	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1198114008227	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1198114008228	DPG_synthase is involved in protein N-linked glycosylation; Region: DPG_synthase; cd04188
1198114008229	Ligand binding site; other site
1198114008230	Ligand binding site; other site
1198114008231	Ligand binding site; other site
1198114008232	Putative Catalytic site; other site
1198114008233	DXD motif; other site
1198114008234	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1198114008235	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1198114008236	tandem repeat interface [polypeptide binding]; other site
1198114008237	oligomer interface [polypeptide binding]; other site
1198114008238	active site residues [active]
1198114008239	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1198114008240	IHF dimer interface [polypeptide binding]; other site
1198114008241	IHF - DNA interface [nucleotide binding]; other site
1198114008242	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1198114008243	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1198114008244	Walker A/P-loop; other site
1198114008245	ATP binding site [chemical binding]; other site
1198114008246	Q-loop/lid; other site
1198114008247	ABC transporter signature motif; other site
1198114008248	Walker B; other site
1198114008249	D-loop; other site
1198114008250	H-loop/switch region; other site
1198114008251	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1198114008252	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1198114008253	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1198114008254	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1198114008255	active site
1198114008256	catalytic residue [active]
1198114008257	dimer interface [polypeptide binding]; other site
1198114008258	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
1198114008259	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1198114008260	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1198114008261	shikimate binding site; other site
1198114008262	NAD(P) binding site [chemical binding]; other site
1198114008263	primosomal protein N' Region: priA; TIGR00595
1198114008264	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1198114008265	ATP binding site [chemical binding]; other site
1198114008266	putative Mg++ binding site [ion binding]; other site
1198114008267	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1198114008268	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1198114008269	IHF - DNA interface [nucleotide binding]; other site
1198114008270	IHF dimer interface [polypeptide binding]; other site
1198114008271	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1198114008272	trimer interface [polypeptide binding]; other site
1198114008273	active site
1198114008274	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114008275	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1198114008276	active site
1198114008277	dimerization interface [polypeptide binding]; other site
1198114008278	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114008279	DNA binding residues [nucleotide binding]
1198114008280	dimerization interface [polypeptide binding]; other site
1198114008281	The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524
1198114008282	putative amphipathic alpha helix; other site
1198114008283	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1198114008284	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1198114008285	putative acyl-acceptor binding pocket; other site
1198114008286	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
1198114008287	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1198114008288	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1198114008289	trimer interface [polypeptide binding]; other site
1198114008290	active site
1198114008291	UDP-GlcNAc binding site [chemical binding]; other site
1198114008292	lipid binding site [chemical binding]; lipid-binding site
1198114008293	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
1198114008294	bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645
1198114008295	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
1198114008296	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1198114008297	FAD binding site [chemical binding]; other site
1198114008298	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1198114008299	Zeta toxin; Region: Zeta_toxin; pfam06414
1198114008300	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
1198114008301	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1198114008302	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1198114008303	substrate binding pocket [chemical binding]; other site
1198114008304	chain length determination region; other site
1198114008305	substrate-Mg2+ binding site; other site
1198114008306	catalytic residues [active]
1198114008307	aspartate-rich region 1; other site
1198114008308	active site lid residues [active]
1198114008309	aspartate-rich region 2; other site
1198114008310	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1198114008311	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1198114008312	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1198114008313	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1198114008314	active site
1198114008315	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114008316	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
1198114008317	Fe-S cluster binding site [ion binding]; other site
1198114008318	active site
1198114008319	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1198114008320	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1198114008321	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1198114008322	catalytic site [active]
1198114008323	G-X2-G-X-G-K; other site
1198114008324	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1198114008325	hypothetical protein; Provisional; Region: PRK11820
1198114008326	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1198114008327	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1198114008328	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
1198114008329	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1198114008330	Walker A/P-loop; other site
1198114008331	ATP binding site [chemical binding]; other site
1198114008332	Q-loop/lid; other site
1198114008333	ABC transporter signature motif; other site
1198114008334	Walker B; other site
1198114008335	D-loop; other site
1198114008336	H-loop/switch region; other site
1198114008337	GxxExxY protein; Region: GxxExxY; TIGR04256
1198114008338	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1198114008339	Subfamily of the nitroreductase family that includes BluB protein in Rhodobacter capsulatus is involved in the conversion of cobinamide to cobalamin in Cobalamin (vitamin B12) biosynthesis. Nitroreductases typically reduce their substrates by using NAD(P)...; Region: BluB; cd02145
1198114008340	putative FMN binding site [chemical binding]; other site
1198114008341	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1198114008342	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1198114008343	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
1198114008344	motif 1; other site
1198114008345	dimer interface [polypeptide binding]; other site
1198114008346	active site
1198114008347	motif 2; other site
1198114008348	motif 3; other site
1198114008349	von Willebrand factor type A domain; Region: VWA_2; pfam13519
1198114008350	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1198114008351	Recombination protein O N terminal; Region: RecO_N; pfam11967
1198114008352	Recombination protein O C terminal; Region: RecO_C; pfam02565
1198114008353	Ferredoxin [Energy production and conversion]; Region: COG1146
1198114008354	4Fe-4S binding domain; Region: Fer4; cl02805
1198114008355	Uncharacterized conserved protein [Function unknown]; Region: COG4104
1198114008356	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1198114008357	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1198114008358	active site
1198114008359	dimerization interface [polypeptide binding]; other site
1198114008360	PemK-like protein; Region: PemK; cl00995
1198114008361	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1198114008362	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114008363	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114008364	metal ion-dependent adhesion site (MIDAS); other site
1198114008365	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1198114008366	MoaE homodimer interface [polypeptide binding]; other site
1198114008367	MoaD interaction [polypeptide binding]; other site
1198114008368	active site residues [active]
1198114008369	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1198114008370	MoaE interaction surface [polypeptide binding]; other site
1198114008371	MoeB interaction surface [polypeptide binding]; other site
1198114008372	thiocarboxylated glycine; other site
1198114008373	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1198114008374	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1198114008375	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114008376	Walker A motif; other site
1198114008377	ATP binding site [chemical binding]; other site
1198114008378	Walker B motif; other site
1198114008379	arginine finger; other site
1198114008380	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1198114008381	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
1198114008382	Prephenate dehydratase; Region: PDT; pfam00800
1198114008383	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1198114008384	putative L-Phe binding site [chemical binding]; other site
1198114008385	CsbD-like; Region: CsbD; pfam05532
1198114008386	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1198114008387	UbiA prenyltransferase family; Region: UbiA; pfam01040
1198114008388	Family of unknown function (DUF490); Region: DUF490; pfam04357
1198114008389	MutS domain III; Region: MutS_III; cl17822
1198114008390	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114008391	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114008392	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1198114008393	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114008394	Surface antigen; Region: Bac_surface_Ag; pfam01103
1198114008395	thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688
1198114008396	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1198114008397	ATP binding site [chemical binding]; other site
1198114008398	substrate interface [chemical binding]; other site
1198114008399	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1198114008400	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114008401	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114008402	DNA binding residues [nucleotide binding]
1198114008403	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
1198114008404	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
1198114008405	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1198114008406	dimer interface [polypeptide binding]; other site
1198114008407	ADP-ribose binding site [chemical binding]; other site
1198114008408	active site
1198114008409	nudix motif; other site
1198114008410	metal binding site [ion binding]; metal-binding site
1198114008411	Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141
1198114008412	hypothetical protein; Provisional; Region: PRK08609
1198114008413	active site
1198114008414	primer binding site [nucleotide binding]; other site
1198114008415	NTP  binding site [chemical binding]; other site
1198114008416	metal binding triad [ion binding]; metal-binding site
1198114008417	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
1198114008418	active site
1198114008419	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114008420	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114008421	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114008422	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
1198114008423	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1198114008424	Zn binding site [ion binding]; other site
1198114008425	protoheme IX farnesyltransferase; Region: cyoE_ctaB; TIGR01473
1198114008426	UbiA prenyltransferase family; Region: UbiA; pfam01040
1198114008427	Protein of unknown function (DUF420); Region: DUF420; pfam04238
1198114008428	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1198114008429	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1198114008430	dimer interface [polypeptide binding]; other site
1198114008431	ssDNA binding site [nucleotide binding]; other site
1198114008432	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1198114008433	Cytochrome c [Energy production and conversion]; Region: COG3258
1198114008434	Cytochrome c; Region: Cytochrom_C; pfam00034
1198114008435	Protein of unknown function (DUF1634); Region: DUF1634; pfam07843
1198114008436	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1198114008437	DsrE/DsrF-like family; Region: DrsE; cl00672
1198114008438	TIGR03118 family protein; Region: PEPCTERM_chp_1
1198114008439	mercuric reductase; Validated; Region: PRK06370
1198114008440	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1198114008441	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1198114008442	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1198114008443	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cl00238
1198114008444	putative iron binding site [ion binding]; other site
1198114008445	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114008446	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1198114008447	putative metal binding site; other site
1198114008448	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
1198114008449	active site
1198114008450	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1198114008451	active site
1198114008452	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114008453	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114008454	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1198114008455	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114008456	putative substrate translocation pore; other site
1198114008457	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1198114008458	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114008459	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1198114008460	putative substrate translocation pore; other site
1198114008461	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
1198114008462	active site
1198114008463	catalytic triad [active]
1198114008464	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114008465	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114008466	metal ion-dependent adhesion site (MIDAS); other site
1198114008467	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
1198114008468	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1198114008469	Lipopolysaccharide-assembly; Region: LptE; pfam04390
1198114008470	FtsH Extracellular; Region: FtsH_ext; pfam06480
1198114008471	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1198114008472	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114008473	Walker A motif; other site
1198114008474	ATP binding site [chemical binding]; other site
1198114008475	Walker B motif; other site
1198114008476	arginine finger; other site
1198114008477	Peptidase family M41; Region: Peptidase_M41; pfam01434
1198114008478	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1198114008479	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1198114008480	Ligand Binding Site [chemical binding]; other site
1198114008481	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1198114008482	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1198114008483	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1198114008484	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114008485	non-specific DNA binding site [nucleotide binding]; other site
1198114008486	salt bridge; other site
1198114008487	sequence-specific DNA binding site [nucleotide binding]; other site
1198114008488	phosphoglucomutase; Validated; Region: PRK07564
1198114008489	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1198114008490	active site
1198114008491	substrate binding site [chemical binding]; other site
1198114008492	metal binding site [ion binding]; metal-binding site
1198114008493	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114008494	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114008495	metal binding site [ion binding]; metal-binding site
1198114008496	active site
1198114008497	I-site; other site
1198114008498	Transmembrane secretion effector; Region: MFS_3; pfam05977
1198114008499	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114008500	putative substrate translocation pore; other site
1198114008501	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
1198114008502	active site
1198114008503	substrate-binding site [chemical binding]; other site
1198114008504	metal-binding site [ion binding]
1198114008505	GTP binding site [chemical binding]; other site
1198114008506	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1198114008507	active site
1198114008508	catalytic triad [active]
1198114008509	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1198114008510	active site
1198114008511	catalytic triad [active]
1198114008512	NIPSNAP; Region: NIPSNAP; pfam07978
1198114008513	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1198114008514	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1198114008515	cell division protein FtsZ; Validated; Region: PRK09330
1198114008516	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1198114008517	nucleotide binding site [chemical binding]; other site
1198114008518	SulA interaction site; other site
1198114008519	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
1198114008520	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1198114008521	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114008522	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1198114008523	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1198114008524	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1198114008525	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114008526	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
1198114008527	Cell division protein FtsA; Region: FtsA; smart00842
1198114008528	Cell division protein FtsA; Region: FtsA; pfam14450
1198114008529	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1198114008530	Cell division protein FtsQ; Region: FtsQ; pfam03799
1198114008531	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1198114008532	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1198114008533	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1198114008534	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1198114008535	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114008536	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1198114008537	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1198114008538	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
1198114008539	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
1198114008540	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1198114008541	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1198114008542	active site
1198114008543	homodimer interface [polypeptide binding]; other site
1198114008544	cell division protein FtsW; Region: ftsW; TIGR02614
1198114008545	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK14106
1198114008546	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1198114008547	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1198114008548	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1198114008549	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1198114008550	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114008551	putative substrate translocation pore; other site
1198114008552	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1198114008553	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1198114008554	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1198114008555	Mg++ binding site [ion binding]; other site
1198114008556	putative catalytic motif [active]
1198114008557	putative substrate binding site [chemical binding]; other site
1198114008558	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1198114008559	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1198114008560	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1198114008561	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1198114008562	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1198114008563	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1198114008564	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1198114008565	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1198114008566	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1198114008567	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1198114008568	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1198114008569	Cell division protein FtsL; Region: FtsL; cl11433
1198114008570	MraW methylase family; Region: Methyltransf_5; cl17771
1198114008571	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1198114008572	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001
1198114008573	MraZ protein; Region: MraZ; pfam02381
1198114008574	MraZ protein; Region: MraZ; pfam02381
1198114008575	Predicted membrane protein (DUF2127); Region: DUF2127; pfam09900
1198114008576	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
1198114008577	Fasciclin domain; Region: Fasciclin; pfam02469
1198114008578	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
1198114008579	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
1198114008580	Secretin and TonB N terminus short domain; Region: STN; smart00965
1198114008581	Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774
1198114008582	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1198114008583	N-terminal plug; other site
1198114008584	ligand-binding site [chemical binding]; other site
1198114008585	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1198114008586	hydrophobic ligand binding site; other site
1198114008587	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
1198114008588	Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A; Region: PNGaseA; pfam12222
1198114008589	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1198114008590	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1198114008591	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1198114008592	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1198114008593	Protein of unknown function (DUF497); Region: DUF497; pfam04365
1198114008594	Protein of unknown function DUF91; Region: DUF91; cl00709
1198114008595	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1198114008596	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1198114008597	TPP-binding site; other site
1198114008598	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1198114008599	PYR/PP interface [polypeptide binding]; other site
1198114008600	dimer interface [polypeptide binding]; other site
1198114008601	TPP binding site [chemical binding]; other site
1198114008602	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1198114008603	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1198114008604	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1198114008605	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
1198114008606	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
1198114008607	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114008608	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114008609	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114008610	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1198114008611	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1198114008612	protein binding site [polypeptide binding]; other site
1198114008613	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
1198114008614	Domain interface; other site
1198114008615	Peptide binding site; other site
1198114008616	Active site tetrad [active]
1198114008617	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1198114008618	GAF domain; Region: GAF; cl17456
1198114008619	PAS domain; Region: PAS_9; pfam13426
1198114008620	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114008621	putative active site [active]
1198114008622	heme pocket [chemical binding]; other site
1198114008623	PAS domain S-box; Region: sensory_box; TIGR00229
1198114008624	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114008625	putative active site [active]
1198114008626	heme pocket [chemical binding]; other site
1198114008627	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1198114008628	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114008629	putative active site [active]
1198114008630	heme pocket [chemical binding]; other site
1198114008631	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114008632	dimer interface [polypeptide binding]; other site
1198114008633	phosphorylation site [posttranslational modification]
1198114008634	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114008635	ATP binding site [chemical binding]; other site
1198114008636	Mg2+ binding site [ion binding]; other site
1198114008637	G-X-G motif; other site
1198114008638	acetyl-CoA synthetase; Provisional; Region: PRK00174
1198114008639	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1198114008640	active site
1198114008641	CoA binding site [chemical binding]; other site
1198114008642	acyl-activating enzyme (AAE) consensus motif; other site
1198114008643	AMP binding site [chemical binding]; other site
1198114008644	acetate binding site [chemical binding]; other site
1198114008645	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1198114008646	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114008647	putative substrate translocation pore; other site
1198114008648	Predicted membrane protein [Function unknown]; Region: COG2323
1198114008649	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1198114008650	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1198114008651	NAD binding site [chemical binding]; other site
1198114008652	homodimer interface [polypeptide binding]; other site
1198114008653	active site
1198114008654	substrate binding site [chemical binding]; other site
1198114008655	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114008656	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1198114008657	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1198114008658	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1198114008659	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1198114008660	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114008661	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1198114008662	dimerization interface [polypeptide binding]; other site
1198114008663	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
1198114008664	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1198114008665	active site
1198114008666	catalytic residues [active]
1198114008667	metal binding site [ion binding]; metal-binding site
1198114008668	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1198114008669	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1198114008670	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1198114008671	substrate binding site [chemical binding]; other site
1198114008672	ligand binding site [chemical binding]; other site
1198114008673	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1198114008674	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1198114008675	substrate binding site [chemical binding]; other site
1198114008676	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1198114008677	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
1198114008678	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1198114008679	PYR/PP interface [polypeptide binding]; other site
1198114008680	dimer interface [polypeptide binding]; other site
1198114008681	TPP binding site [chemical binding]; other site
1198114008682	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1198114008683	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1198114008684	TPP-binding site [chemical binding]; other site
1198114008685	dimer interface [polypeptide binding]; other site
1198114008686	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1198114008687	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1198114008688	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1198114008689	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1198114008690	putative valine binding site [chemical binding]; other site
1198114008691	dimer interface [polypeptide binding]; other site
1198114008692	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1198114008693	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1198114008694	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1198114008695	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1198114008696	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114008697	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114008698	ligand binding site [chemical binding]; other site
1198114008699	flexible hinge region; other site
1198114008700	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114008701	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114008702	ATP binding site [chemical binding]; other site
1198114008703	Mg2+ binding site [ion binding]; other site
1198114008704	G-X-G motif; other site
1198114008705	Domain of unknown function (DUF427); Region: DUF427; pfam04248
1198114008706	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1198114008707	DNA topoisomerase I, bacterial; Region: topA_bact; TIGR01051
1198114008708	active site
1198114008709	interdomain interaction site; other site
1198114008710	putative metal-binding site [ion binding]; other site
1198114008711	nucleotide binding site [chemical binding]; other site
1198114008712	Bacterial DNA topoisomeraes I ATP-binding domain; Region: TOP1Bc; smart00436
1198114008713	domain I; other site
1198114008714	phosphate binding site [ion binding]; other site
1198114008715	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1198114008716	domain II; other site
1198114008717	domain III; other site
1198114008718	nucleotide binding site [chemical binding]; other site
1198114008719	DNA binding groove [nucleotide binding]
1198114008720	catalytic site [active]
1198114008721	domain IV; other site
1198114008722	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1198114008723	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1198114008724	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1198114008725	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1198114008726	DNA protecting protein DprA; Region: dprA; TIGR00732
1198114008727	Menaquinone biosynthesis; Region: VitK2_biosynth; pfam02621
1198114008728	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1198114008729	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1198114008730	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1198114008731	dimer interface [polypeptide binding]; other site
1198114008732	active site
1198114008733	CoA binding pocket [chemical binding]; other site
1198114008734	MutS domain III; Region: MutS_III; cl17822
1198114008735	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114008736	Walker A/P-loop; other site
1198114008737	ATP binding site [chemical binding]; other site
1198114008738	Q-loop/lid; other site
1198114008739	ABC transporter signature motif; other site
1198114008740	Walker B; other site
1198114008741	D-loop; other site
1198114008742	H-loop/switch region; other site
1198114008743	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1198114008744	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1198114008745	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1198114008746	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1198114008747	NAD(P) binding site [chemical binding]; other site
1198114008748	catalytic residues [active]
1198114008749	Protein of unknown function (DUF779); Region: DUF779; pfam05610
1198114008750	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1198114008751	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1198114008752	putative carbohydrate kinase; Provisional; Region: PRK10565
1198114008753	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1198114008754	putative substrate binding site [chemical binding]; other site
1198114008755	putative ATP binding site [chemical binding]; other site
1198114008756	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1198114008757	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1198114008758	TPP-binding site [chemical binding]; other site
1198114008759	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1198114008760	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114008761	DNA-binding site [nucleotide binding]; DNA binding site
1198114008762	RNA-binding motif; other site
1198114008763	cytidylate kinase; Provisional; Region: cmk; PRK00023
1198114008764	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1198114008765	CMP-binding site; other site
1198114008766	The sites determining sugar specificity; other site
1198114008767	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1198114008768	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114008769	ATP binding site [chemical binding]; other site
1198114008770	Mg2+ binding site [ion binding]; other site
1198114008771	G-X-G motif; other site
1198114008772	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1198114008773	ATP binding site [chemical binding]; other site
1198114008774	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1198114008775	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114008776	putative active site [active]
1198114008777	pyruvate kinase; Provisional; Region: PRK05826
1198114008778	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1198114008779	domain interfaces; other site
1198114008780	active site
1198114008781	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1198114008782	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1198114008783	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114008784	catalytic residues [active]
1198114008785	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114008786	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114008787	metal ion-dependent adhesion site (MIDAS); other site
1198114008788	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1198114008789	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114008790	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
1198114008791	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114008792	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114008793	ligand binding site [chemical binding]; other site
1198114008794	flexible hinge region; other site
1198114008795	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1198114008796	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
1198114008797	TadE-like protein; Region: TadE; pfam07811
1198114008798	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
1198114008799	TadE-like protein; Region: TadE; pfam07811
1198114008800	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1198114008801	SelR domain; Region: SelR; pfam01641
1198114008802	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
1198114008803	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
1198114008804	Predicted integral membrane protein [Function unknown]; Region: COG5616
1198114008805	TPR repeat; Region: TPR_11; pfam13414
1198114008806	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114008807	TPR motif; other site
1198114008808	TPR repeat; Region: TPR_11; pfam13414
1198114008809	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114008810	binding surface
1198114008811	TPR motif; other site
1198114008812	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
1198114008813	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_1; cd07020
1198114008814	dimer interface [polypeptide binding]; other site
1198114008815	active site residues [active]
1198114008816	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
1198114008817	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1198114008818	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1198114008819	Sporulation related domain; Region: SPOR; pfam05036
1198114008820	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1198114008821	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1198114008822	putative acyl-acceptor binding pocket; other site
1198114008823	UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane]; Region: MurC; COG0773
1198114008824	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1198114008825	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1198114008826	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1198114008827	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1198114008828	dimer interface [polypeptide binding]; other site
1198114008829	catalytic triad [active]
1198114008830	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1198114008831	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1198114008832	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1198114008833	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1198114008834	MgtC family; Region: MgtC; pfam02308
1198114008835	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1198114008836	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1198114008837	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1198114008838	substrate binding site [chemical binding]; other site
1198114008839	ATP binding site [chemical binding]; other site
1198114008840	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1198114008841	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
1198114008842	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1198114008843	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1198114008844	Domain of unknown function (DUF1844); Region: DUF1844; pfam08899
1198114008845	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114008846	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1198114008847	putative hydrolase; Provisional; Region: PRK02113
1198114008848	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1198114008849	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1198114008850	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1198114008851	active site
1198114008852	Riboflavin kinase; Region: Flavokinase; pfam01687
1198114008853	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1198114008854	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1198114008855	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1198114008856	protein binding site [polypeptide binding]; other site
1198114008857	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1198114008858	Active site serine [active]
1198114008859	HD domain; Region: HD_3; pfam13023
1198114008860	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1198114008861	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1198114008862	Ligand binding site; other site
1198114008863	oligomer interface; other site
1198114008864	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
1198114008865	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1198114008866	This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible...; Region: PGM_like2; cd05800
1198114008867	active site
1198114008868	substrate binding site [chemical binding]; other site
1198114008869	metal binding site [ion binding]; metal-binding site
1198114008870	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
1198114008871	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1198114008872	Substrate binding site; other site
1198114008873	Cupin domain; Region: Cupin_2; cl17218
1198114008874	aspartate aminotransferase; Provisional; Region: PRK05764
1198114008875	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1198114008876	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114008877	homodimer interface [polypeptide binding]; other site
1198114008878	catalytic residue [active]
1198114008879	TPR repeat; Region: TPR_11; pfam13414
1198114008880	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114008881	TPR motif; other site
1198114008882	binding surface
1198114008883	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1198114008884	catalytic residues [active]
1198114008885	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1198114008886	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1198114008887	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1198114008888	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1198114008889	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114008890	S-adenosylmethionine binding site [chemical binding]; other site
1198114008891	Peptidases of the G1 family, including scytalidoglutamic peptidase and aspergillopepsin; Region: Peptidase_G1; cd13426
1198114008892	polypeptide substrate binding site [polypeptide binding]; other site
1198114008893	active site
1198114008894	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1198114008895	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1198114008896	active site
1198114008897	(T/H)XGH motif; other site
1198114008898	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1198114008899	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114008900	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114008901	DNA binding residues [nucleotide binding]
1198114008902	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1198114008903	dimer interface [polypeptide binding]; other site
1198114008904	recombinase A; Provisional; Region: recA; PRK09354
1198114008905	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1198114008906	hexamer interface [polypeptide binding]; other site
1198114008907	Walker A motif; other site
1198114008908	ATP binding site [chemical binding]; other site
1198114008909	Walker B motif; other site
1198114008910	Thymidylate synthase complementing protein; Region: Thy1; cl03630
1198114008911	Thymidylate synthase complementing protein; Region: Thy1; cl03630
1198114008912	Uncharacterized conserved protein (COG2071); Region: DUF2071; pfam09844
1198114008913	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
1198114008914	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1198114008915	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1198114008916	NAD(P) binding site [chemical binding]; other site
1198114008917	homotetramer interface [polypeptide binding]; other site
1198114008918	homodimer interface [polypeptide binding]; other site
1198114008919	active site
1198114008920	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114008921	PAS domain; Region: PAS_9; pfam13426
1198114008922	putative active site [active]
1198114008923	heme pocket [chemical binding]; other site
1198114008924	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1198114008925	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114008926	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114008927	putative active site [active]
1198114008928	heme pocket [chemical binding]; other site
1198114008929	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114008930	dimer interface [polypeptide binding]; other site
1198114008931	phosphorylation site [posttranslational modification]
1198114008932	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114008933	ATP binding site [chemical binding]; other site
1198114008934	Mg2+ binding site [ion binding]; other site
1198114008935	G-X-G motif; other site
1198114008936	Predicted methyltransferases [General function prediction only]; Region: COG0313
1198114008937	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1198114008938	putative SAM binding site [chemical binding]; other site
1198114008939	putative homodimer interface [polypeptide binding]; other site
1198114008940	SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F...; Region: S2P-M50_SpoIVFB; cd06161
1198114008941	active site
1198114008942	Peptidase family M50; Region: Peptidase_M50; pfam02163
1198114008943	putative substrate binding region [chemical binding]; other site
1198114008944	FOG: CBS domain [General function prediction only]; Region: COG0517
1198114008945	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1198114008946	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1198114008947	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1198114008948	cystathionine gamma-lyase; Validated; Region: PRK07582
1198114008949	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114008950	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114008951	catalytic residue [active]
1198114008952	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1198114008953	thiamine monophosphate kinase; Provisional; Region: PRK05731
1198114008954	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1198114008955	ATP binding site [chemical binding]; other site
1198114008956	dimerization interface [polypeptide binding]; other site
1198114008957	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1198114008958	Peptidase family M23; Region: Peptidase_M23; pfam01551
1198114008959	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1198114008960	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1198114008961	dimer interface [polypeptide binding]; other site
1198114008962	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114008963	catalytic residue [active]
1198114008964	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding); Region: MPN_like; cd08070
1198114008965	MPN+ (JAMM) motif; other site
1198114008966	Zinc-binding site [ion binding]; other site
1198114008967	Ubiquitin-like proteins; Region: UBQ; cl00155
1198114008968	charged pocket; other site
1198114008969	hydrophobic patch; other site
1198114008970	hypothetical protein; Validated; Region: PRK07411
1198114008971	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1198114008972	ATP binding site [chemical binding]; other site
1198114008973	substrate interface [chemical binding]; other site
1198114008974	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1198114008975	active site residue [active]
1198114008976	homoserine dehydrogenase; Provisional; Region: PRK06349
1198114008977	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1198114008978	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1198114008979	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1198114008980	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1198114008981	nucleoside/Zn binding site; other site
1198114008982	dimer interface [polypeptide binding]; other site
1198114008983	catalytic motif [active]
1198114008984	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114008985	allantoinase; Region: allantoinase; TIGR03178
1198114008986	active site
1198114008987	putative OHCU decarboxylase; Provisional; Region: PRK13798
1198114008988	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1198114008989	active site
1198114008990	homotetramer interface [polypeptide binding]; other site
1198114008991	urate oxidase; Region: urate_oxi; TIGR03383
1198114008992	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1198114008993	active site
1198114008994	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1198114008995	allantoate amidohydrolase; Reviewed; Region: PRK12890
1198114008996	active site
1198114008997	metal binding site [ion binding]; metal-binding site
1198114008998	dimer interface [polypeptide binding]; other site
1198114008999	hypothetical protein; Provisional; Region: PRK11171
1198114009000	Cupin domain; Region: Cupin_2; pfam07883
1198114009001	allantoate amidohydrolase; Reviewed; Region: PRK09290
1198114009002	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1198114009003	active site
1198114009004	metal binding site [ion binding]; metal-binding site
1198114009005	dimer interface [polypeptide binding]; other site
1198114009006	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1198114009007	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1198114009008	NAD(P) binding site [chemical binding]; other site
1198114009009	catalytic residues [active]
1198114009010	Middle domain of rhamnogalacturonan lyase, a family 4 polysaccharide lyase; Region: RGL4_M; cd10316
1198114009011	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114009012	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
1198114009013	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114009014	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1198114009015	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1198114009016	PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; Region: PDZ_signaling; cd00992
1198114009017	protein binding site [polypeptide binding]; other site
1198114009018	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
1198114009019	Domain interface; other site
1198114009020	Peptide binding site; other site
1198114009021	Active site tetrad [active]
1198114009022	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1198114009023	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1198114009024	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1198114009025	catalytic site [active]
1198114009026	active site
1198114009027	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1198114009028	maltooligosyl trehalose synthase; Provisional; Region: PRK14511
1198114009029	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1198114009030	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1198114009031	active site
1198114009032	catalytic site [active]
1198114009033	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
1198114009034	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1198114009035	Domain of unknown function (DUF3416); Region: DUF3416; pfam11896
1198114009036	Alpha amylase catalytic domain found in GlgE-like proteins; Region: AmyAc_GlgE_like; cd11344
1198114009037	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1198114009038	active site
1198114009039	homodimer interface [polypeptide binding]; other site
1198114009040	catalytic site [active]
1198114009041	acceptor binding site [chemical binding]; other site
1198114009042	trehalose synthase; Region: treS_nterm; TIGR02456
1198114009043	Alpha amylase catalytic domain found in Trehalose synthetase; Region: AmyAc_TreS; cd11334
1198114009044	active site
1198114009045	catalytic site [active]
1198114009046	Uncharacterized protein, probably involved in trehalose biosynthesis [Carbohydrate transport and metabolism]; Region: Ble; COG3281
1198114009047	Domain of unknown function (DUF373); Region: DUF373; cl12079
1198114009048	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1198114009049	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1198114009050	Ligand binding site; other site
1198114009051	metal-binding site
1198114009052	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1198114009053	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1198114009054	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1198114009055	PilZ domain; Region: PilZ; pfam07238
1198114009056	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1198114009057	Zn2+ binding site [ion binding]; other site
1198114009058	Mg2+ binding site [ion binding]; other site
1198114009059	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1198114009060	GAF domain; Region: GAF_3; pfam13492
1198114009061	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114009062	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114009063	metal binding site [ion binding]; metal-binding site
1198114009064	active site
1198114009065	I-site; other site
1198114009066	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1198114009067	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1198114009068	conserved gate region; other site
1198114009069	dimer interface [polypeptide binding]; other site
1198114009070	putative PBP binding loops; other site
1198114009071	ABC-ATPase subunit interface; other site
1198114009072	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1198114009073	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1198114009074	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_4; cd08500
1198114009075	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1198114009076	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1198114009077	Walker A/P-loop; other site
1198114009078	ATP binding site [chemical binding]; other site
1198114009079	Q-loop/lid; other site
1198114009080	ABC transporter signature motif; other site
1198114009081	Walker B; other site
1198114009082	D-loop; other site
1198114009083	H-loop/switch region; other site
1198114009084	type VII secretion-associated serine protease mycosin; Region: T7SS_mycosin; TIGR03921
1198114009085	Peptidase S8 family domain, uncharacterized subfamily 1; Region: Peptidases_S8_1; cd07487
1198114009086	active site
1198114009087	catalytic triad [active]
1198114009088	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114009089	PAS domain; Region: PAS_9; pfam13426
1198114009090	putative active site [active]
1198114009091	heme pocket [chemical binding]; other site
1198114009092	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1198114009093	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1198114009094	metal binding site [ion binding]; metal-binding site
1198114009095	active site
1198114009096	I-site; other site
1198114009097	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114009098	putative aminotransferase; Provisional; Region: PRK09105
1198114009099	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1198114009100	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114009101	homodimer interface [polypeptide binding]; other site
1198114009102	catalytic residue [active]
1198114009103	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_3; cd06151
1198114009104	homotrimer interaction site [polypeptide binding]; other site
1198114009105	putative active site [active]
1198114009106	Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231
1198114009107	Protein of unknown function (DUF503); Region: DUF503; cl00669
1198114009108	Ribosome-binding factor A; Region: RBFA; cl00542
1198114009109	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1198114009110	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
1198114009111	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114009112	Coenzyme A binding pocket [chemical binding]; other site
1198114009113	Predicted integral membrane protein [Function unknown]; Region: COG5652
1198114009114	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1198114009115	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1198114009116	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1198114009117	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1198114009118	active site
1198114009119	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114009120	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114009121	Predicted transcriptional regulators [Transcription]; Region: COG1733
1198114009122	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1198114009123	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1198114009124	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1198114009125	NADP binding site [chemical binding]; other site
1198114009126	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
1198114009127	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1198114009128	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1198114009129	Sm and related proteins; Region: Sm_like; cl00259
1198114009130	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1198114009131	putative oligomer interface [polypeptide binding]; other site
1198114009132	putative RNA binding site [nucleotide binding]; other site
1198114009133	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1198114009134	NusA N-terminal domain; Region: NusA_N; pfam08529
1198114009135	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1198114009136	RNA binding site [nucleotide binding]; other site
1198114009137	homodimer interface [polypeptide binding]; other site
1198114009138	NusA-like KH domain; Region: KH_5; pfam13184
1198114009139	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1198114009140	G-X-X-G motif; other site
1198114009141	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1198114009142	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1198114009143	translation initiation factor IF-2; Region: IF-2; TIGR00487
1198114009144	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1198114009145	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1198114009146	G1 box; other site
1198114009147	putative GEF interaction site [polypeptide binding]; other site
1198114009148	GTP/Mg2+ binding site [chemical binding]; other site
1198114009149	Switch I region; other site
1198114009150	G2 box; other site
1198114009151	G3 box; other site
1198114009152	Switch II region; other site
1198114009153	G4 box; other site
1198114009154	G5 box; other site
1198114009155	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1198114009156	Translation-initiation factor 2; Region: IF-2; pfam11987
1198114009157	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1198114009158	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1198114009159	DNA-binding site [nucleotide binding]; DNA binding site
1198114009160	RNA-binding motif; other site
1198114009161	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1198114009162	Metallopeptidase family M24; Region: Peptidase_M24; pfam00557
1198114009163	active site
1198114009164	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1198114009165	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
1198114009166	four helix bundle protein; Region: TIGR02436
1198114009167	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1198114009168	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1198114009169	alphaNTD homodimer interface [polypeptide binding]; other site
1198114009170	alphaNTD - beta interaction site [polypeptide binding]; other site
1198114009171	alphaNTD - beta' interaction site [polypeptide binding]; other site
1198114009172	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1198114009173	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1198114009174	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1198114009175	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1198114009176	RNA binding surface [nucleotide binding]; other site
1198114009177	30S ribosomal protein S11; Validated; Region: PRK05309
1198114009178	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1198114009179	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1198114009180	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1198114009181	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1198114009182	rRNA binding site [nucleotide binding]; other site
1198114009183	predicted 30S ribosome binding site; other site
1198114009184	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1198114009185	active site
1198114009186	adenylate kinase; Reviewed; Region: adk; PRK00279
1198114009187	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1198114009188	AMP-binding site [chemical binding]; other site
1198114009189	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1198114009190	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1198114009191	SecY translocase; Region: SecY; pfam00344
1198114009192	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1198114009193	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1198114009194	23S rRNA binding site [nucleotide binding]; other site
1198114009195	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1198114009196	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1198114009197	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1198114009198	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1198114009199	23S rRNA interface [nucleotide binding]; other site
1198114009200	L21e interface [polypeptide binding]; other site
1198114009201	5S rRNA interface [nucleotide binding]; other site
1198114009202	L27 interface [polypeptide binding]; other site
1198114009203	L5 interface [polypeptide binding]; other site
1198114009204	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1198114009205	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1198114009206	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1198114009207	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1198114009208	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1198114009209	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1198114009210	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1198114009211	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1198114009212	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1198114009213	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1198114009214	RNA binding site [nucleotide binding]; other site
1198114009215	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1198114009216	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1198114009217	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1198114009218	putative translocon interaction site; other site
1198114009219	23S rRNA interface [nucleotide binding]; other site
1198114009220	signal recognition particle (SRP54) interaction site; other site
1198114009221	L23 interface [polypeptide binding]; other site
1198114009222	trigger factor interaction site; other site
1198114009223	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1198114009224	23S rRNA interface [nucleotide binding]; other site
1198114009225	5S rRNA interface [nucleotide binding]; other site
1198114009226	putative antibiotic binding site [chemical binding]; other site
1198114009227	L25 interface [polypeptide binding]; other site
1198114009228	L27 interface [polypeptide binding]; other site
1198114009229	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1198114009230	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1198114009231	G-X-X-G motif; other site
1198114009232	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1198114009233	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1198114009234	putative translocon binding site; other site
1198114009235	protein-rRNA interface [nucleotide binding]; other site
1198114009236	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1198114009237	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1198114009238	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1198114009239	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1198114009240	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1198114009241	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1198114009242	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1198114009243	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1198114009244	elongation factor Tu; Reviewed; Region: PRK00049
1198114009245	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1198114009246	G1 box; other site
1198114009247	GEF interaction site [polypeptide binding]; other site
1198114009248	GTP/Mg2+ binding site [chemical binding]; other site
1198114009249	Switch I region; other site
1198114009250	G2 box; other site
1198114009251	G3 box; other site
1198114009252	Switch II region; other site
1198114009253	G4 box; other site
1198114009254	G5 box; other site
1198114009255	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1198114009256	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1198114009257	Antibiotic Binding Site [chemical binding]; other site
1198114009258	elongation factor G; Reviewed; Region: PRK00007
1198114009259	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1198114009260	G1 box; other site
1198114009261	putative GEF interaction site [polypeptide binding]; other site
1198114009262	GTP/Mg2+ binding site [chemical binding]; other site
1198114009263	Switch I region; other site
1198114009264	G2 box; other site
1198114009265	G3 box; other site
1198114009266	Switch II region; other site
1198114009267	G4 box; other site
1198114009268	G5 box; other site
1198114009269	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1198114009270	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1198114009271	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1198114009272	30S ribosomal protein S7; Validated; Region: PRK05302
1198114009273	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1198114009274	S17 interaction site [polypeptide binding]; other site
1198114009275	S8 interaction site; other site
1198114009276	16S rRNA interaction site [nucleotide binding]; other site
1198114009277	streptomycin interaction site [chemical binding]; other site
1198114009278	23S rRNA interaction site [nucleotide binding]; other site
1198114009279	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1198114009280	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1198114009281	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114009282	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114009283	transcription antitermination factor NusB; Region: nusB; TIGR01951
1198114009284	putative RNA binding site [nucleotide binding]; other site
1198114009285	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1198114009286	homopentamer interface [polypeptide binding]; other site
1198114009287	active site
1198114009288	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
1198114009289	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1198114009290	substrate binding site [chemical binding]; other site
1198114009291	oxyanion hole (OAH) forming residues; other site
1198114009292	trimer interface [polypeptide binding]; other site
1198114009293	GTPase Era; Reviewed; Region: era; PRK00089
1198114009294	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1198114009295	G1 box; other site
1198114009296	GTP/Mg2+ binding site [chemical binding]; other site
1198114009297	Switch I region; other site
1198114009298	G2 box; other site
1198114009299	Switch II region; other site
1198114009300	G3 box; other site
1198114009301	G4 box; other site
1198114009302	G5 box; other site
1198114009303	KH domain; Region: KH_2; pfam07650
1198114009304	soil-associated protein, TIGR03435 family; Region: Soli_TIGR03435
1198114009305	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1198114009306	Transporter associated domain; Region: CorC_HlyC; smart01091
1198114009307	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
1198114009308	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1198114009309	PhoH-like protein; Region: PhoH; pfam02562
1198114009310	Penicillinase repressor; Region: Pencillinase_R; cl17580
1198114009311	Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component [Transcription / Signal transduction mechanisms]; Region: MecR1; COG4219
1198114009312	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1198114009313	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114009314	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1198114009315	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1198114009316	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1198114009317	active site
1198114009318	Zn binding site [ion binding]; other site
1198114009319	EamA-like transporter family; Region: EamA; pfam00892
1198114009320	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1198114009321	EamA-like transporter family; Region: EamA; pfam00892
1198114009322	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114009323	threonine synthase; Validated; Region: PRK08197
1198114009324	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
1198114009325	homodimer interface [polypeptide binding]; other site
1198114009326	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114009327	catalytic residue [active]
1198114009328	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1198114009329	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114009330	active site
1198114009331	motif I; other site
1198114009332	motif II; other site
1198114009333	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1198114009334	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1198114009335	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1198114009336	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1198114009337	catalytic residue [active]
1198114009338	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1198114009339	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1198114009340	ATP cone domain; Region: ATP-cone; pfam03477
1198114009341	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
1198114009342	isocitrate dehydrogenase; Validated; Region: PRK06451
1198114009343	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1198114009344	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
1198114009345	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1198114009346	aspartate kinase III; Validated; Region: PRK09084
1198114009347	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
1198114009348	putative catalytic residues [active]
1198114009349	nucleotide binding site [chemical binding]; other site
1198114009350	aspartate binding site [chemical binding]; other site
1198114009351	ACT domains located C-terminal to the catalytic domain of  the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC-like_1; cd04912
1198114009352	dimer interface [polypeptide binding]; other site
1198114009353	allosteric regulatory binding pocket; other site
1198114009354	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1198114009355	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1198114009356	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1198114009357	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1198114009358	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1198114009359	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1198114009360	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1198114009361	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1198114009362	dimer interface [polypeptide binding]; other site
1198114009363	active site
1198114009364	catalytic residue [active]
1198114009365	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1198114009366	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1198114009367	trimer interface [polypeptide binding]; other site
1198114009368	active site
1198114009369	substrate binding site [chemical binding]; other site
1198114009370	CoA binding site [chemical binding]; other site
1198114009371	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1198114009372	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114009373	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1198114009374	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1198114009375	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1198114009376	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1198114009377	ligand binding site [chemical binding]; other site
1198114009378	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1198114009379	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1198114009380	tetramer interface [polypeptide binding]; other site
1198114009381	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114009382	catalytic residue [active]
1198114009383	SnoaL-like domain; Region: SnoaL_2; pfam12680
1198114009384	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1198114009385	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1198114009386	putative DNA binding site [nucleotide binding]; other site
1198114009387	putative Zn2+ binding site [ion binding]; other site
1198114009388	hypothetical protein; Validated; Region: PRK01415
1198114009389	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1198114009390	active site residue [active]
1198114009391	Bacitracin resistance protein BacA; Region: BacA; pfam02673
1198114009392	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114009393	PGAP1-like protein; Region: PGAP1; pfam07819
1198114009394	atypical (a) SDRs, subgroup 7; Region: SDR_a7; cd05262
1198114009395	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1198114009396	putative NAD(P) binding site [chemical binding]; other site
1198114009397	DinB family; Region: DinB; cl17821
1198114009398	Predicted transcriptional regulator [Transcription]; Region: COG2378
1198114009399	HTH domain; Region: HTH_11; pfam08279
1198114009400	WYL domain; Region: WYL; pfam13280
1198114009401	Predicted membrane protein [Function unknown]; Region: COG4270
1198114009402	Domain of unknown function (DUF2383); Region: DUF2383; cl17556
1198114009403	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1198114009404	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1198114009405	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1198114009406	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1198114009407	Protein of unknown function (DUF3999); Region: DUF3999; pfam13163
1198114009408	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
1198114009409	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114009410	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114009411	active site
1198114009412	phosphorylation site [posttranslational modification]
1198114009413	intermolecular recognition site; other site
1198114009414	dimerization interface [polypeptide binding]; other site
1198114009415	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
1198114009416	putative binding surface; other site
1198114009417	active site
1198114009418	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114009419	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114009420	active site
1198114009421	phosphorylation site [posttranslational modification]
1198114009422	intermolecular recognition site; other site
1198114009423	dimerization interface [polypeptide binding]; other site
1198114009424	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114009425	DNA binding residues [nucleotide binding]
1198114009426	dimerization interface [polypeptide binding]; other site
1198114009427	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
1198114009428	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
1198114009429	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1198114009430	putative active site [active]
1198114009431	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
1198114009432	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1198114009433	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1198114009434	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1198114009435	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114009436	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
1198114009437	Walker A/P-loop; other site
1198114009438	ATP binding site [chemical binding]; other site
1198114009439	Q-loop/lid; other site
1198114009440	ABC transporter signature motif; other site
1198114009441	Walker B; other site
1198114009442	D-loop; other site
1198114009443	H-loop/switch region; other site
1198114009444	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1198114009445	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114009446	NAD(P) binding site [chemical binding]; other site
1198114009447	active site
1198114009448	Domain of unknown function (DUF4398); Region: DUF4398; pfam14346
1198114009449	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1198114009450	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1198114009451	ligand binding site [chemical binding]; other site
1198114009452	Gas vesicle synthesis protein GvpL/GvpF; Region: GvpL_GvpF; pfam06386
1198114009453	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1198114009454	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1198114009455	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114009456	putative active site [active]
1198114009457	heme pocket [chemical binding]; other site
1198114009458	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114009459	dimer interface [polypeptide binding]; other site
1198114009460	phosphorylation site [posttranslational modification]
1198114009461	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114009462	ATP binding site [chemical binding]; other site
1198114009463	Mg2+ binding site [ion binding]; other site
1198114009464	G-X-G motif; other site
1198114009465	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
1198114009466	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1198114009467	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1198114009468	Family description; Region: VCBS; pfam13517
1198114009469	Family description; Region: VCBS; pfam13517
1198114009470	Family description; Region: VCBS; pfam13517
1198114009471	Family description; Region: VCBS; pfam13517
1198114009472	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1198114009473	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1198114009474	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1198114009475	NAD(P) binding site [chemical binding]; other site
1198114009476	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
1198114009477	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1198114009478	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1198114009479	Rift valley fever virus non structural protein (NSs) like; Region: NSs; pfam11073
1198114009480	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
1198114009481	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1198114009482	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1198114009483	glutamine binding [chemical binding]; other site
1198114009484	catalytic triad [active]
1198114009485	translation elongation factor P; Region: efp; TIGR00038
1198114009486	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1198114009487	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1198114009488	RNA binding site [nucleotide binding]; other site
1198114009489	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1198114009490	RNA binding site [nucleotide binding]; other site
1198114009491	Acylphosphatase; Region: Acylphosphatase; pfam00708
1198114009492	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1198114009493	active site
1198114009494	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1198114009495	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1198114009496	putative NAD(P) binding site [chemical binding]; other site
1198114009497	putative substrate binding site [chemical binding]; other site
1198114009498	catalytic Zn binding site [ion binding]; other site
1198114009499	structural Zn binding site [ion binding]; other site
1198114009500	dimer interface [polypeptide binding]; other site
1198114009501	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1198114009502	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114009503	arginine decarboxylase; Provisional; Region: PRK15029
1198114009504	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1198114009505	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1198114009506	homodimer interface [polypeptide binding]; other site
1198114009507	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114009508	catalytic residue [active]
1198114009509	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1198114009510	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14314
1198114009511	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1198114009512	active site
1198114009513	substrate binding site [chemical binding]; other site
1198114009514	metal binding site [ion binding]; metal-binding site
1198114009515	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1198114009516	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1198114009517	generic binding surface I; other site
1198114009518	generic binding surface II; other site
1198114009519	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114009520	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114009521	active site
1198114009522	phosphorylation site [posttranslational modification]
1198114009523	intermolecular recognition site; other site
1198114009524	dimerization interface [polypeptide binding]; other site
1198114009525	Ion channel; Region: Ion_trans_2; pfam07885
1198114009526	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1198114009527	23S rRNA interface [nucleotide binding]; other site
1198114009528	L3 interface [polypeptide binding]; other site
1198114009529	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1198114009530	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1198114009531	rRNA interaction site [nucleotide binding]; other site
1198114009532	S8 interaction site; other site
1198114009533	putative laminin-1 binding site; other site
1198114009534	elongation factor Ts; Reviewed; Region: tsf; PRK12332
1198114009535	UBA/TS-N domain; Region: UBA; pfam00627
1198114009536	Elongation factor TS; Region: EF_TS; pfam00889
1198114009537	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1198114009538	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1198114009539	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1198114009540	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1198114009541	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1198114009542	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1198114009543	histidinol dehydrogenase; Region: hisD; TIGR00069
1198114009544	NAD binding site [chemical binding]; other site
1198114009545	dimerization interface [polypeptide binding]; other site
1198114009546	product binding site; other site
1198114009547	substrate binding site [chemical binding]; other site
1198114009548	zinc binding site [ion binding]; other site
1198114009549	catalytic residues [active]
1198114009550	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
1198114009551	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1198114009552	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114009553	homodimer interface [polypeptide binding]; other site
1198114009554	catalytic residue [active]
1198114009555	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1198114009556	putative active site pocket [active]
1198114009557	4-fold oligomerization interface [polypeptide binding]; other site
1198114009558	metal binding residues [ion binding]; metal-binding site
1198114009559	3-fold/trimer interface [polypeptide binding]; other site
1198114009560	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
1198114009561	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1198114009562	putative active site [active]
1198114009563	oxyanion strand; other site
1198114009564	catalytic triad [active]
1198114009565	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
1198114009566	lipoyl-biotinyl attachment site [posttranslational modification]; other site
1198114009567	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1198114009568	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1198114009569	substrate binding site [chemical binding]; other site
1198114009570	glutamase interaction surface [polypeptide binding]; other site
1198114009571	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1198114009572	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1198114009573	phosphate binding site [ion binding]; other site
1198114009574	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114009575	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114009576	metal ion-dependent adhesion site (MIDAS); other site
1198114009577	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114009578	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1198114009579	EamA-like transporter family; Region: EamA; pfam00892
1198114009580	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
1198114009581	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1198114009582	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1198114009583	ligand binding site; other site
1198114009584	oligomer interface; other site
1198114009585	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1198114009586	dimer interface [polypeptide binding]; other site
1198114009587	N-terminal domain interface [polypeptide binding]; other site
1198114009588	sulfate 1 binding site; other site
1198114009589	ATP10 protein; Region: ATP-synt_10; pfam05176
1198114009590	Domain of unknown function (DUF427); Region: DUF427; cl00998
1198114009591	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1198114009592	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
1198114009593	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1198114009594	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1198114009595	lipoyl attachment site [posttranslational modification]; other site
1198114009596	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
1198114009597	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1198114009598	tetramer interface [polypeptide binding]; other site
1198114009599	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114009600	catalytic residue [active]
1198114009601	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1198114009602	tetramer interface [polypeptide binding]; other site
1198114009603	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114009604	catalytic residue [active]
1198114009605	Pectic acid lyase; Region: Pec_lyase; pfam09492
1198114009606	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
1198114009607	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114009608	hypothetical protein; Validated; Region: PRK00029
1198114009609	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1198114009610	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1198114009611	active site
1198114009612	DNA binding site [nucleotide binding]
1198114009613	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114009614	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1198114009615	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114009616	Outer membrane efflux protein; Region: OEP; pfam02321
1198114009617	Outer membrane efflux protein; Region: OEP; pfam02321
1198114009618	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114009619	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114009620	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1198114009621	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114009622	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1198114009623	dimerization interface [polypeptide binding]; other site
1198114009624	substrate binding pocket [chemical binding]; other site
1198114009625	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
1198114009626	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114009627	Protein of unknown function (DUF433); Region: DUF433; pfam04255
1198114009628	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1198114009629	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1198114009630	Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs; Region: Piwi_piwi-like_ProArk; cd04659
1198114009631	5' RNA guide strand anchoring site; other site
1198114009632	active site
1198114009633	NIPSNAP; Region: NIPSNAP; pfam07978
1198114009634	Putative metallopeptidase domain; Region: DUF2201_N; pfam13203
1198114009635	FRG domain; Region: FRG; pfam08867
1198114009636	FRG domain; Region: FRG; cl07460
1198114009637	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1198114009638	ParB-like nuclease domain; Region: ParB; smart00470
1198114009639	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1198114009640	LDH/MDH dimer interface [polypeptide binding]; other site
1198114009641	NAD(P) binding site [chemical binding]; other site
1198114009642	substrate binding site [chemical binding]; other site
1198114009643	Condensation domain; Region: Condensation; pfam00668
1198114009644	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
1198114009645	Horizontally Transferred TransMembrane Domain; Region: HTTM; smart00752
1198114009646	SnoaL-like domain; Region: SnoaL_4; pfam13577
1198114009647	Predicted transcriptional regulators [Transcription]; Region: COG1733
1198114009648	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1198114009649	malate dehydrogenase; Provisional; Region: PRK13529
1198114009650	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1198114009651	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1198114009652	NAD(P) binding site [chemical binding]; other site
1198114009653	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1198114009654	Class II fumarases; Region: Fumarase_classII; cd01362
1198114009655	active site
1198114009656	tetramer interface [polypeptide binding]; other site
1198114009657	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
1198114009658	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1198114009659	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
1198114009660	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114009661	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114009662	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114009663	Cupin domain; Region: Cupin_2; pfam07883
1198114009664	Cupin domain; Region: Cupin_2; pfam07883
1198114009665	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1198114009666	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1198114009667	FMN binding site [chemical binding]; other site
1198114009668	active site
1198114009669	substrate binding site [chemical binding]; other site
1198114009670	catalytic residue [active]
1198114009671	Cupin domain; Region: Cupin_2; cl17218
1198114009672	Cupin domain; Region: Cupin_2; pfam07883
1198114009673	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1198114009674	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
1198114009675	oxidoreductase; Provisional; Region: PRK06196
1198114009676	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
1198114009677	putative NAD(P) binding site [chemical binding]; other site
1198114009678	active site
1198114009679	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114009680	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114009681	active site
1198114009682	phosphorylation site [posttranslational modification]
1198114009683	intermolecular recognition site; other site
1198114009684	dimerization interface [polypeptide binding]; other site
1198114009685	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114009686	DNA binding residues [nucleotide binding]
1198114009687	dimerization interface [polypeptide binding]; other site
1198114009688	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1198114009689	Two component regulator propeller; Region: Reg_prop; pfam07494
1198114009690	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1198114009691	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1198114009692	Histidine kinase; Region: HisKA_3; pfam07730
1198114009693	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114009694	ATP binding site [chemical binding]; other site
1198114009695	Mg2+ binding site [ion binding]; other site
1198114009696	G-X-G motif; other site
1198114009697	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1198114009698	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114009699	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114009700	short chain dehydrogenase; Provisional; Region: PRK06500
1198114009701	classical (c) SDRs; Region: SDR_c; cd05233
1198114009702	NAD(P) binding site [chemical binding]; other site
1198114009703	active site
1198114009704	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1198114009705	active site
1198114009706	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1198114009707	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1198114009708	NAD(P) binding site [chemical binding]; other site
1198114009709	Nitroreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_2; cd02138
1198114009710	putative FMN binding site [chemical binding]; other site
1198114009711	short chain dehydrogenase; Provisional; Region: PRK08263
1198114009712	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1198114009713	NADP binding site [chemical binding]; other site
1198114009714	active site
1198114009715	steroid binding site; other site
1198114009716	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1198114009717	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114009718	NAD(P) binding site [chemical binding]; other site
1198114009719	active site
1198114009720	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1198114009721	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1198114009722	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1198114009723	ParB-like nuclease domain; Region: ParB; smart00470
1198114009724	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114009725	metabolite-proton symporter; Region: 2A0106; TIGR00883
1198114009726	putative substrate translocation pore; other site
1198114009727	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1198114009728	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114009729	Walker A/P-loop; other site
1198114009730	ATP binding site [chemical binding]; other site
1198114009731	Q-loop/lid; other site
1198114009732	ABC transporter signature motif; other site
1198114009733	Walker B; other site
1198114009734	D-loop; other site
1198114009735	H-loop/switch region; other site
1198114009736	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1198114009737	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114009738	non-specific DNA binding site [nucleotide binding]; other site
1198114009739	salt bridge; other site
1198114009740	sequence-specific DNA binding site [nucleotide binding]; other site
1198114009741	hypothetical protein; Provisional; Region: PRK07236
1198114009742	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
1198114009743	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1198114009744	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1198114009745	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114009746	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114009747	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114009748	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1198114009749	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114009750	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114009751	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
1198114009752	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1198114009753	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1198114009754	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1198114009755	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114009756	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1198114009757	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1198114009758	FMN binding site [chemical binding]; other site
1198114009759	active site
1198114009760	substrate binding site [chemical binding]; other site
1198114009761	catalytic residue [active]
1198114009762	TrwC relaxase; Region: TrwC; pfam08751
1198114009763	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1198114009764	AAA domain; Region: AAA_30; pfam13604
1198114009765	Family description; Region: UvrD_C_2; pfam13538
1198114009766	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114009767	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
1198114009768	Walker A motif; other site
1198114009769	ATP binding site [chemical binding]; other site
1198114009770	Walker B motif; other site
1198114009771	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1198114009772	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1198114009773	dimer interface [polypeptide binding]; other site
1198114009774	ssDNA binding site [nucleotide binding]; other site
1198114009775	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1198114009776	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1198114009777	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1198114009778	Walker A motif; other site
1198114009779	ATP binding site [chemical binding]; other site
1198114009780	Walker B motif; other site
1198114009781	VirB8 protein; Region: VirB8; cl01500
1198114009782	conjugal transfer protein TrbI; Provisional; Region: PRK13881
1198114009783	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1198114009784	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
1198114009785	VirB7 interaction site; other site
1198114009786	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1198114009787	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1198114009788	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
1198114009789	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1198114009790	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114009791	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1198114009792	dimerization interface [polypeptide binding]; other site
1198114009793	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114009794	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1198114009795	active site
1198114009796	DNA binding site [nucleotide binding]
1198114009797	Int/Topo IB signature motif; other site
1198114009798	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1198114009799	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114009800	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114009801	DNA binding residues [nucleotide binding]
1198114009802	Putative zinc-finger; Region: zf-HC2; pfam13490
1198114009803	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
1198114009804	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1198114009805	dimerization interface [polypeptide binding]; other site
1198114009806	active site
1198114009807	metal binding site [ion binding]; metal-binding site
1198114009808	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1198114009809	dsRNA binding site [nucleotide binding]; other site
1198114009810	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1198114009811	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1198114009812	Catalytic site [active]
1198114009813	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1198114009814	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1198114009815	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1198114009816	Catalytic site [active]
1198114009817	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1198114009818	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1198114009819	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1198114009820	Zn binding site [ion binding]; other site
1198114009821	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1198114009822	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1198114009823	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1198114009824	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1198114009825	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114009826	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114009827	DNA binding residues [nucleotide binding]
1198114009828	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1198114009829	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1198114009830	Double zinc ribbon; Region: DZR; pfam12773
1198114009831	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1198114009832	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114009833	active site
1198114009834	phosphorylation site [posttranslational modification]
1198114009835	intermolecular recognition site; other site
1198114009836	dimerization interface [polypeptide binding]; other site
1198114009837	LytTr DNA-binding domain; Region: LytTR; smart00850
1198114009838	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1198114009839	S-adenosylmethionine binding site [chemical binding]; other site
1198114009840	fructokinase; Reviewed; Region: PRK09557
1198114009841	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1198114009842	nucleotide binding site [chemical binding]; other site
1198114009843	Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; Region: HemeO; cl17299
1198114009844	heme binding pocket [chemical binding]; other site
1198114009845	GAF domain; Region: GAF; pfam01590
1198114009846	Phytochrome region; Region: PHY; pfam00360
1198114009847	PAS fold; Region: PAS_4; pfam08448
1198114009848	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114009849	putative active site [active]
1198114009850	heme pocket [chemical binding]; other site
1198114009851	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114009852	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114009853	dimer interface [polypeptide binding]; other site
1198114009854	phosphorylation site [posttranslational modification]
1198114009855	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114009856	ATP binding site [chemical binding]; other site
1198114009857	Mg2+ binding site [ion binding]; other site
1198114009858	G-X-G motif; other site
1198114009859	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1198114009860	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1198114009861	Predicted transcriptional regulators [Transcription]; Region: COG1695
1198114009862	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1198114009863	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1198114009864	Walker A/P-loop; other site
1198114009865	ATP binding site [chemical binding]; other site
1198114009866	Q-loop/lid; other site
1198114009867	ABC transporter signature motif; other site
1198114009868	Walker B; other site
1198114009869	D-loop; other site
1198114009870	H-loop/switch region; other site
1198114009871	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1198114009872	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1198114009873	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK06476
1198114009874	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1198114009875	galactokinase; Provisional; Region: PRK05101
1198114009876	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1198114009877	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1198114009878	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1198114009879	dimer interface [polypeptide binding]; other site
1198114009880	active site
1198114009881	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1198114009882	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1198114009883	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1198114009884	active site
1198114009885	catalytic residues [active]
1198114009886	SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases; Region: XynE_like; cd01830
1198114009887	active site
1198114009888	catalytic triad [active]
1198114009889	oxyanion hole [active]
1198114009890	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1198114009891	active site
1198114009892	multimer interface [polypeptide binding]; other site
1198114009893	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1198114009894	CoA binding domain; Region: CoA_binding; smart00881
1198114009895	CoA-ligase; Region: Ligase_CoA; pfam00549
1198114009896	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1198114009897	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1198114009898	CoA-ligase; Region: Ligase_CoA; pfam00549
1198114009899	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1198114009900	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1198114009901	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114009902	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1198114009903	active site
1198114009904	thymidine kinase; Provisional; Region: PRK04296
1198114009905	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1198114009906	Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939
1198114009907	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
1198114009908	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114009909	salt bridge; other site
1198114009910	non-specific DNA binding site [nucleotide binding]; other site
1198114009911	sequence-specific DNA binding site [nucleotide binding]; other site
1198114009912	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1198114009913	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1198114009914	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1198114009915	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1198114009916	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1198114009917	E-class dimer interface [polypeptide binding]; other site
1198114009918	P-class dimer interface [polypeptide binding]; other site
1198114009919	active site
1198114009920	Cu2+ binding site [ion binding]; other site
1198114009921	Zn2+ binding site [ion binding]; other site
1198114009922	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1198114009923	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1198114009924	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1198114009925	DNA binding residues [nucleotide binding]
1198114009926	Putative zinc-finger; Region: zf-HC2; pfam13490
1198114009927	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1198114009928	heat shock protein 90; Provisional; Region: PRK05218
1198114009929	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114009930	ATP binding site [chemical binding]; other site
1198114009931	Mg2+ binding site [ion binding]; other site
1198114009932	G-X-G motif; other site
1198114009933	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114009934	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
1198114009935	Predicted aminopeptidases [General function prediction only]; Region: Iap; COG2234
1198114009936	PA/protease or protease-like domain interface [polypeptide binding]; other site
1198114009937	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114009938	metal binding site [ion binding]; metal-binding site
1198114009939	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114009940	hypothetical protein; Provisional; Region: PRK09133
1198114009941	M20 Peptidase, carboxypeptidase yscS-like; Region: M20_yscS_like; cd05675
1198114009942	putative metal binding site [ion binding]; other site
1198114009943	Domain of unknown function (DUF4337); Region: DUF4337; pfam14235
1198114009944	MarC family integral membrane protein; Region: MarC; pfam01914
1198114009945	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1198114009946	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1198114009947	homodimer interface [polypeptide binding]; other site
1198114009948	substrate-cofactor binding pocket; other site
1198114009949	catalytic residue [active]
1198114009950	quinohemoprotein amine dehydrogenase, beta subunit; Region: QH_beta; TIGR03907
1198114009951	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1198114009952	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1198114009953	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1198114009954	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1198114009955	Coenzyme A binding pocket [chemical binding]; other site
1198114009956	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1198114009957	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1198114009958	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1198114009959	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1198114009960	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1198114009961	Predicted transcriptional regulator [Transcription]; Region: COG3905
1198114009962	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1198114009963	Predicted ATPase [General function prediction only]; Region: COG3910
1198114009964	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114009965	Walker A/P-loop; other site
1198114009966	ATP binding site [chemical binding]; other site
1198114009967	Q-loop/lid; other site
1198114009968	ABC transporter signature motif; other site
1198114009969	Walker B; other site
1198114009970	D-loop; other site
1198114009971	H-loop/switch region; other site
1198114009972	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1198114009973	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1198114009974	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1198114009975	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1198114009976	catalytic residue [active]
1198114009977	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1198114009978	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
1198114009979	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
1198114009980	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1198114009981	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114009982	PA_M28_1_1: Protease-associated (PA) domain, peptidase family M28, subfamily-1, subgroup 1. A subgroup of PA-domain containing proteins belonging to the peptidase family M28. Family M28 contains aminopeptidases and carboxypeptidases, and has co-catalytic...; Region: PA_M28_1_1; cd04820
1198114009983	PA/protease or protease-like domain interface [polypeptide binding]; other site
1198114009984	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114009985	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114009986	metal binding site [ion binding]; metal-binding site
1198114009987	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1198114009988	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1198114009989	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1198114009990	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114009991	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114009992	active site
1198114009993	catalytic tetrad [active]
1198114009994	Protein of unknown function (DUF3606); Region: DUF3606; pfam12244
1198114009995	Uncharacterized protein conserved in bacteria (DUF2218); Region: DUF2218; pfam09981
1198114009996	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114009997	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
1198114009998	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1198114009999	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114010000	catalytic residues [active]
1198114010001	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010002	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1198114010003	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1198114010004	N-terminal plug; other site
1198114010005	ligand-binding site [chemical binding]; other site
1198114010006	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
1198114010007	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
1198114010008	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1198114010009	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1198114010010	Na binding site [ion binding]; other site
1198114010011	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
1198114010012	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
1198114010013	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
1198114010014	soil-associated protein, TIGR03435 family; Region: Soli_TIGR03435
1198114010015	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114010016	M28 Zn-Peptidases; Region: M28_like_4; cd08015
1198114010017	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114010018	metal binding site [ion binding]; metal-binding site
1198114010019	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114010020	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114010021	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114010022	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114010023	Uncharacterized protein conserved in bacteria (DUF2237); Region: DUF2237; pfam09996
1198114010024	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1198114010025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1198114010026	Walker A/P-loop; other site
1198114010027	ATP binding site [chemical binding]; other site
1198114010028	Q-loop/lid; other site
1198114010029	ABC transporter signature motif; other site
1198114010030	Walker B; other site
1198114010031	D-loop; other site
1198114010032	H-loop/switch region; other site
1198114010033	ABC transporter; Region: ABC_tran_2; pfam12848
1198114010034	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1198114010035	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1198114010036	Predicted acyl esterases [General function prediction only]; Region: COG2936
1198114010037	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1198114010038	helicase 45; Provisional; Region: PTZ00424
1198114010039	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1198114010040	ATP binding site [chemical binding]; other site
1198114010041	Mg++ binding site [ion binding]; other site
1198114010042	motif III; other site
1198114010043	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1198114010044	nucleotide binding region [chemical binding]; other site
1198114010045	ATP-binding site [chemical binding]; other site
1198114010046	RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526
1198114010047	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
1198114010048	Ligand binding site; other site
1198114010049	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1198114010050	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1198114010051	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1198114010052	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114010053	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
1198114010054	Probable Catalytic site; other site
1198114010055	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1198114010056	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114010057	Amidase; Region: Amidase; cl11426
1198114010058	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010059	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114010060	Amidase; Region: Amidase; pfam01425
1198114010061	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1198114010062	Amidase; Region: Amidase; pfam01425
1198114010063	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1198114010064	EamA-like transporter family; Region: EamA; pfam00892
1198114010065	EamA-like transporter family; Region: EamA; pfam00892
1198114010066	Predicted integral membrane protein [Function unknown]; Region: COG5616
1198114010067	TPR repeat; Region: TPR_11; pfam13414
1198114010068	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114010069	binding surface
1198114010070	TPR motif; other site
1198114010071	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114010072	TPR motif; other site
1198114010073	binding surface
1198114010074	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114010075	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114010076	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114010077	active site
1198114010078	dimerization interface [polypeptide binding]; other site
1198114010079	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114010080	DNA binding site [nucleotide binding]
1198114010081	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1198114010082	dimerization interface [polypeptide binding]; other site
1198114010083	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114010084	dimer interface [polypeptide binding]; other site
1198114010085	phosphorylation site [posttranslational modification]
1198114010086	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
1198114010087	Mg2+ binding site [ion binding]; other site
1198114010088	G-X-G motif; other site
1198114010089	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114010090	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114010091	active site
1198114010092	phosphorylation site [posttranslational modification]
1198114010093	intermolecular recognition site; other site
1198114010094	dimerization interface [polypeptide binding]; other site
1198114010095	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114010096	DNA binding site [nucleotide binding]
1198114010097	Predicted transcriptional regulators [Transcription]; Region: COG1695
1198114010098	transcriptional regulator, Acidobacterial, PadR-family; Region: padR_acidobact; TIGR03433
1198114010099	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
1198114010100	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114010101	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1198114010102	FtsX-like permease family; Region: FtsX; pfam02687
1198114010103	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
1198114010104	active site
1198114010105	catalytic site [active]
1198114010106	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1198114010107	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
1198114010108	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1198114010109	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1198114010110	active site
1198114010111	Int/Topo IB signature motif; other site
1198114010112	catalytic residues [active]
1198114010113	DNA binding site [nucleotide binding]
1198114010114	Phage DNA packaging protein Nu1; Region: Phage_Nu1; cl01720
1198114010115	AntA/AntB antirepressor; Region: AntA; pfam08346
1198114010116	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
1198114010117	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1198114010118	Helix-turn-helix domain; Region: HTH_17; pfam12728
1198114010119	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1198114010120	DNA polymerase III subunit alpha; Reviewed; Region: PRK09532
1198114010121	TIGR04255 family protein; Region: sporadTIGR04255
1198114010122	dimethyl sulfone monooxygenase SfnG; Region: LLM_DMSO2_sfnG; TIGR04021
1198114010123	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1198114010124	active site
1198114010125	dimer interface [polypeptide binding]; other site
1198114010126	non-prolyl cis peptide bond; other site
1198114010127	insertion regions; other site
1198114010128	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
1198114010129	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1198114010130	Amino acid permease; Region: AA_permease_2; pfam13520
1198114010131	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1198114010132	dimer interface [polypeptide binding]; other site
1198114010133	substrate binding site [chemical binding]; other site
1198114010134	metal binding sites [ion binding]; metal-binding site
1198114010135	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
1198114010136	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1198114010137	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1198114010138	substrate binding site [chemical binding]; other site
1198114010139	active site
1198114010140	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1198114010141	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
1198114010142	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1198114010143	nucleotide binding site [chemical binding]; other site
1198114010144	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1198114010145	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1198114010146	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
1198114010147	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1198114010148	dimerization interface [polypeptide binding]; other site
1198114010149	active site
1198114010150	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
1198114010151	RNA/DNA hybrid binding site [nucleotide binding]; other site
1198114010152	active site
1198114010153	Yqey-like protein; Region: YqeY; pfam09424
1198114010154	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1198114010155	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114010156	catalytic residue [active]
1198114010157	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1198114010158	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
1198114010159	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1198114010160	Methyltransferase domain; Region: Methyltransf_11; pfam08241
1198114010161	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
1198114010162	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1198114010163	active site
1198114010164	catalytic residues [active]
1198114010165	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1198114010166	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1198114010167	active site
1198114010168	HIGH motif; other site
1198114010169	nucleotide binding site [chemical binding]; other site
1198114010170	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1198114010171	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1198114010172	active site
1198114010173	KMSKS motif; other site
1198114010174	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1198114010175	tRNA binding surface [nucleotide binding]; other site
1198114010176	anticodon binding site; other site
1198114010177	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1198114010178	Outer membrane lipoprotein; Region: YfiO; pfam13525
1198114010179	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1198114010180	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1198114010181	substrate binding site [chemical binding]; other site
1198114010182	hexamer interface [polypeptide binding]; other site
1198114010183	metal binding site [ion binding]; metal-binding site
1198114010184	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
1198114010185	GIY-YIG motif/motif A; other site
1198114010186	active site
1198114010187	catalytic site [active]
1198114010188	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1198114010189	protease TldD; Provisional; Region: tldD; PRK10735
1198114010190	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
1198114010191	active site
1198114010192	metal-dependent hydrolase; Provisional; Region: PRK13291
1198114010193	DinB superfamily; Region: DinB_2; pfam12867
1198114010194	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1198114010195	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114010196	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114010197	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114010198	Outer membrane efflux protein; Region: OEP; pfam02321
1198114010199	Outer membrane efflux protein; Region: OEP; pfam02321
1198114010200	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1198114010201	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1198114010202	G1 box; other site
1198114010203	putative GEF interaction site [polypeptide binding]; other site
1198114010204	GTP/Mg2+ binding site [chemical binding]; other site
1198114010205	Switch I region; other site
1198114010206	G2 box; other site
1198114010207	G3 box; other site
1198114010208	Switch II region; other site
1198114010209	G4 box; other site
1198114010210	G5 box; other site
1198114010211	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1198114010212	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1198114010213	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1198114010214	Uncharacterized conserved protein [Function unknown]; Region: COG2308
1198114010215	Domain of unknown function (DUF4415); Region: DUF4415; pfam14384
1198114010216	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
1198114010217	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
1198114010218	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1198114010219	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
1198114010220	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1198114010221	Predicted acyl esterases [General function prediction only]; Region: COG2936
1198114010222	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1198114010223	LabA_like proteins; Region: LabA_like; cd06167
1198114010224	putative metal binding site [ion binding]; other site
1198114010225	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1198114010226	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1198114010227	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114010228	NAD(P) binding site [chemical binding]; other site
1198114010229	active site
1198114010230	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1198114010231	FAD binding domain; Region: FAD_binding_4; pfam01565
1198114010232	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1198114010233	23S rRNA binding site [nucleotide binding]; other site
1198114010234	L21 binding site [polypeptide binding]; other site
1198114010235	L13 binding site [polypeptide binding]; other site
1198114010236	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1198114010237	ornithine--oxo-acid transaminase; Provisional; Region: rocD; PRK04073
1198114010238	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1198114010239	inhibitor-cofactor binding pocket; inhibition site
1198114010240	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114010241	catalytic residue [active]
1198114010242	Protein of unknown function (DUF817); Region: DUF817; pfam05675
1198114010243	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1198114010244	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1198114010245	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114010246	ATP binding site [chemical binding]; other site
1198114010247	Mg2+ binding site [ion binding]; other site
1198114010248	G-X-G motif; other site
1198114010249	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1198114010250	anchoring element; other site
1198114010251	dimer interface [polypeptide binding]; other site
1198114010252	ATP binding site [chemical binding]; other site
1198114010253	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1198114010254	active site
1198114010255	putative metal-binding site [ion binding]; other site
1198114010256	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1198114010257	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1198114010258	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1198114010259	oligomeric interface; other site
1198114010260	homodimer interface [polypeptide binding]; other site
1198114010261	putative active site [active]
1198114010262	Rhomboid family; Region: Rhomboid; cl11446
1198114010263	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114010264	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114010265	metal binding site [ion binding]; metal-binding site
1198114010266	lysine biosynthesis protein LysW; Region: lysW; TIGR01206
1198114010267	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010268	Predicted membrane protein [Function unknown]; Region: COG4682
1198114010269	yiaA/B two helix domain; Region: YiaAB; pfam05360
1198114010270	yiaA/B two helix domain; Region: YiaAB; pfam05360
1198114010271	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114010272	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114010273	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1198114010274	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
1198114010275	putative active site [active]
1198114010276	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1198114010277	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1198114010278	dimer interface [polypeptide binding]; other site
1198114010279	motif 1; other site
1198114010280	active site
1198114010281	motif 2; other site
1198114010282	motif 3; other site
1198114010283	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1198114010284	anticodon binding site; other site
1198114010285	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1198114010286	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1198114010287	trimer interface [polypeptide binding]; other site
1198114010288	putative metal binding site [ion binding]; other site
1198114010289	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1198114010290	Probable zinc-binding domain; Region: zf-trcl; pfam13451
1198114010291	CxxC-x17-CxxC domain; Region: cxxc_cxxc_Mbark; TIGR04272
1198114010292	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114010293	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114010294	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114010295	active site
1198114010296	phosphorylation site [posttranslational modification]
1198114010297	intermolecular recognition site; other site
1198114010298	dimerization interface [polypeptide binding]; other site
1198114010299	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1198114010300	phosphorylation site [posttranslational modification]
1198114010301	dimer interface [polypeptide binding]; other site
1198114010302	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114010303	ATP binding site [chemical binding]; other site
1198114010304	Mg2+ binding site [ion binding]; other site
1198114010305	G-X-G motif; other site
1198114010306	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1198114010307	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114010308	ATP binding site [chemical binding]; other site
1198114010309	Mg2+ binding site [ion binding]; other site
1198114010310	G-X-G motif; other site
1198114010311	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114010312	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114010313	dimer interface [polypeptide binding]; other site
1198114010314	phosphorylation site [posttranslational modification]
1198114010315	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114010316	ATP binding site [chemical binding]; other site
1198114010317	Mg2+ binding site [ion binding]; other site
1198114010318	G-X-G motif; other site
1198114010319	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114010320	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114010321	active site
1198114010322	phosphorylation site [posttranslational modification]
1198114010323	intermolecular recognition site; other site
1198114010324	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1198114010325	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
1198114010326	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1198114010327	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1198114010328	ATP binding site [chemical binding]; other site
1198114010329	Mg2+ binding site [ion binding]; other site
1198114010330	G-X-G motif; other site
1198114010331	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1198114010332	RsbT co-antagonist protein rsbRD N-terminal domain; Region: RsbRD_N; pfam14361
1198114010333	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1198114010334	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010335	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114010336	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
1198114010337	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1198114010338	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1198114010339	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
1198114010340	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1198114010341	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1198114010342	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1198114010343	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1198114010344	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1198114010345	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114010346	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114010347	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114010348	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1198114010349	active site
1198114010350	NTP binding site [chemical binding]; other site
1198114010351	metal binding triad [ion binding]; metal-binding site
1198114010352	antibiotic binding site [chemical binding]; other site
1198114010353	oxidative damage protection protein; Provisional; Region: PRK05408
1198114010354	ribonuclease R; Region: RNase_R; TIGR02063
1198114010355	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1198114010356	RNB domain; Region: RNB; pfam00773
1198114010357	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1198114010358	RNA binding site [nucleotide binding]; other site
1198114010359	RES domain; Region: RES; pfam08808
1198114010360	Protein of unknown function (DUF2384); Region: DUF2384; cl17718
1198114010361	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114010362	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
1198114010363	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114010364	Ferrochelatase; Region: Ferrochelatase; pfam00762
1198114010365	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1198114010366	C-terminal domain interface [polypeptide binding]; other site
1198114010367	active site
1198114010368	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1198114010369	active site
1198114010370	N-terminal domain interface [polypeptide binding]; other site
1198114010371	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
1198114010372	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114010373	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
1198114010374	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1198114010375	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1198114010376	active site
1198114010377	HIGH motif; other site
1198114010378	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1198114010379	KMSKS motif; other site
1198114010380	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1198114010381	UGMP family protein; Validated; Region: PRK09604
1198114010382	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1198114010383	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1198114010384	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1198114010385	active site
1198114010386	NTP binding site [chemical binding]; other site
1198114010387	metal binding triad [ion binding]; metal-binding site
1198114010388	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1198114010389	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1198114010390	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1198114010391	Protein of unknown function (DUF3738); Region: DUF3738; cl11887
1198114010392	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1198114010393	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1198114010394	putative phosphate acyltransferase; Provisional; Region: PRK05331
1198114010395	short chain dehydrogenase; Provisional; Region: PRK06197
1198114010396	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
1198114010397	putative NAD(P) binding site [chemical binding]; other site
1198114010398	active site
1198114010399	aconitate hydratase; Validated; Region: PRK09277
1198114010400	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1198114010401	substrate binding site [chemical binding]; other site
1198114010402	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1198114010403	ligand binding site [chemical binding]; other site
1198114010404	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1198114010405	substrate binding site [chemical binding]; other site
1198114010406	TPR repeat; Region: TPR_11; pfam13414
1198114010407	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114010408	binding surface
1198114010409	TPR motif; other site
1198114010410	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG1964
1198114010411	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114010412	FeS/SAM binding site; other site
1198114010413	Predicted acyl esterases [General function prediction only]; Region: COG2936
1198114010414	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114010415	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1198114010416	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1198114010417	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1198114010418	Sporulation related domain; Region: SPOR; pfam05036
1198114010419	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1198114010420	adenosine deaminase; Provisional; Region: PRK09358
1198114010421	active site
1198114010422	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
1198114010423	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1198114010424	NAD(P) binding site [chemical binding]; other site
1198114010425	active site
1198114010426	amino acid transporter; Region: 2A0306; TIGR00909
1198114010427	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1198114010428	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1198114010429	Part of AAA domain; Region: AAA_19; pfam13245
1198114010430	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
1198114010431	Family description; Region: UvrD_C_2; pfam13538
1198114010432	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2; cl00208
1198114010433	CAS motifs; other site
1198114010434	active site
1198114010435	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1198114010436	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1198114010437	active site
1198114010438	HIGH motif; other site
1198114010439	dimer interface [polypeptide binding]; other site
1198114010440	KMSKS motif; other site
1198114010441	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
1198114010442	RNA binding surface [nucleotide binding]; other site
1198114010443	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114010444	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
1198114010445	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1198114010446	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1198114010447	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510
1198114010448	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1198114010449	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1198114010450	[4Fe-4S] binding site [ion binding]; other site
1198114010451	molybdopterin cofactor binding site; other site
1198114010452	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
1198114010453	molybdopterin cofactor binding site; other site
1198114010454	Uncharacterized conserved protein [Function unknown]; Region: COG2427
1198114010455	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1198114010456	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1198114010457	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1198114010458	MgtC family; Region: MgtC; pfam02308
1198114010459	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
1198114010460	hypothetical protein; Validated; Region: PRK08116
1198114010461	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1198114010462	ATP binding site [chemical binding]; other site
1198114010463	Walker A motif; other site
1198114010464	Walker B motif; other site
1198114010465	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1198114010466	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1198114010467	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1198114010468	FMN binding site [chemical binding]; other site
1198114010469	active site
1198114010470	catalytic residues [active]
1198114010471	substrate binding site [chemical binding]; other site
1198114010472	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1198114010473	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1198114010474	Competence protein; Region: Competence; pfam03772
1198114010475	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1198114010476	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1198114010477	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1198114010478	soil-associated protein, TIGR03435 family; Region: Soli_TIGR03435
1198114010479	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1198114010480	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1198114010481	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1198114010482	thiamine phosphate binding site [chemical binding]; other site
1198114010483	active site
1198114010484	pyrophosphate binding site [ion binding]; other site
1198114010485	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1198114010486	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1198114010487	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1198114010488	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1198114010489	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1198114010490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1198114010491	RelB antitoxin; Region: RelB; cl01171
1198114010492	formamidopyrimidine-DNA glycosylase; Provisional; Region: PRK14810
1198114010493	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1198114010494	DNA binding site [nucleotide binding]
1198114010495	catalytic residue [active]
1198114010496	H2TH interface [polypeptide binding]; other site
1198114010497	putative catalytic residues [active]
1198114010498	turnover-facilitating residue; other site
1198114010499	intercalation triad [nucleotide binding]; other site
1198114010500	8OG recognition residue [nucleotide binding]; other site
1198114010501	putative reading head residues; other site
1198114010502	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1198114010503	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1198114010504	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1198114010505	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1198114010506	GDP-binding site [chemical binding]; other site
1198114010507	ACT binding site; other site
1198114010508	IMP binding site; other site
1198114010509	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1198114010510	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1198114010511	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1198114010512	dihydroorotase; Validated; Region: pyrC; PRK09357
1198114010513	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114010514	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1198114010515	active site
1198114010516	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1198114010517	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
1198114010518	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1198114010519	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1198114010520	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1198114010521	active site
1198114010522	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
1198114010523	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
1198114010524	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1198114010525	DNA binding residues [nucleotide binding]
1198114010526	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1198114010527	Iron-sulphur cluster assembly; Region: Fe-S_assembly; pfam04384
1198114010528	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1198114010529	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1198114010530	putative [4Fe-4S] binding site [ion binding]; other site
1198114010531	putative molybdopterin cofactor binding site [chemical binding]; other site
1198114010532	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
1198114010533	molybdopterin cofactor binding site; other site
1198114010534	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
1198114010535	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1198114010536	SnoaL-like domain; Region: SnoaL_3; pfam13474
1198114010537	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010538	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114010539	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1198114010540	active site
1198114010541	catalytic triad [active]
1198114010542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114010543	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1198114010544	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114010545	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114010546	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114010547	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114010548	Copper type II ascorbate-dependent monooxygenase, C-terminal domain; Region: Cu2_monoox_C; pfam03712
1198114010549	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114010550	TPR motif; other site
1198114010551	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1198114010552	binding surface
1198114010553	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114010554	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114010555	binding surface
1198114010556	TPR motif; other site
1198114010557	TPR repeat; Region: TPR_11; pfam13414
1198114010558	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1198114010559	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114010560	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
1198114010561	active site
1198114010562	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1198114010563	active site
1198114010564	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010565	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
1198114010566	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1198114010567	Cytochrome c; Region: Cytochrom_C; pfam00034
1198114010568	lipoyl synthase; Provisional; Region: PRK05481
1198114010569	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1198114010570	FeS/SAM binding site; other site
1198114010571	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1198114010572	aminotransferase; Validated; Region: PRK07777
1198114010573	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1198114010574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114010575	homodimer interface [polypeptide binding]; other site
1198114010576	catalytic residue [active]
1198114010577	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1198114010578	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1198114010579	hinge region; other site
1198114010580	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1198114010581	dihydropteroate synthase; Region: DHPS; TIGR01496
1198114010582	substrate binding pocket [chemical binding]; other site
1198114010583	dimer interface [polypeptide binding]; other site
1198114010584	inhibitor binding site; inhibition site
1198114010585	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114010586	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114010587	RmuC family; Region: RmuC; pfam02646
1198114010588	Fungal chitosanase of glycosyl hydrolase group 75; Region: Glyco_hydro_75; pfam07335
1198114010589	acyl carrier protein; Provisional; Region: acpP; PRK00982
1198114010590	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1198114010591	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1198114010592	dimer interface [polypeptide binding]; other site
1198114010593	active site
1198114010594	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1198114010595	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1198114010596	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1198114010597	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1198114010598	Response regulator receiver domain; Region: Response_reg; pfam00072
1198114010599	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114010600	active site
1198114010601	phosphorylation site [posttranslational modification]
1198114010602	intermolecular recognition site; other site
1198114010603	dimerization interface [polypeptide binding]; other site
1198114010604	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1198114010605	active site
1198114010606	ribulose/triose binding site [chemical binding]; other site
1198114010607	phosphate binding site [ion binding]; other site
1198114010608	substrate (anthranilate) binding pocket [chemical binding]; other site
1198114010609	product (indole) binding pocket [chemical binding]; other site
1198114010610	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1198114010611	active site
1198114010612	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1198114010613	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1198114010614	active site
1198114010615	catalytic tetrad [active]
1198114010616	Ethanolamine ammonia-lyase light chain (EutC); Region: EutC; cl01762
1198114010617	ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067
1198114010618	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1198114010619	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1198114010620	Beta-lactamase; Region: Beta-lactamase; pfam00144
1198114010621	Catalase-like heme-binding proteins similar to the uncharacterized y4iL; Region: y4iL_like; cd08152
1198114010622	putative heme binding pocket [chemical binding]; other site
1198114010623	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1198114010624	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1198114010625	Walker A/P-loop; other site
1198114010626	ATP binding site [chemical binding]; other site
1198114010627	Q-loop/lid; other site
1198114010628	ABC transporter signature motif; other site
1198114010629	Walker B; other site
1198114010630	D-loop; other site
1198114010631	H-loop/switch region; other site
1198114010632	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1198114010633	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1198114010634	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1198114010635	active site
1198114010636	metal binding site [ion binding]; metal-binding site
1198114010637	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1198114010638	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1198114010639	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1198114010640	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1198114010641	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1198114010642	ABC transporter; Region: ABC_tran_2; pfam12848
1198114010643	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1198114010644	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1198114010645	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
1198114010646	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1198114010647	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1198114010648	inhibitor-cofactor binding pocket; inhibition site
1198114010649	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114010650	catalytic residue [active]
1198114010651	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1198114010652	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1198114010653	dimerization interface [polypeptide binding]; other site
1198114010654	putative ATP binding site [chemical binding]; other site
1198114010655	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1198114010656	Protein of unknown function DUF86; Region: DUF86; cl01031
1198114010657	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
1198114010658	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1198114010659	active site
1198114010660	substrate binding site [chemical binding]; other site
1198114010661	cosubstrate binding site; other site
1198114010662	catalytic site [active]
1198114010663	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114010664	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114010665	metal ion-dependent adhesion site (MIDAS); other site
1198114010666	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1198114010667	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1198114010668	RNA binding surface [nucleotide binding]; other site
1198114010669	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1198114010670	active site
1198114010671	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
1198114010672	Cell division protein ZapA; Region: ZapA; cl01146
1198114010673	Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Region: PheT; COG0072
1198114010674	B3/4 domain; Region: B3_4; pfam03483
1198114010675	tRNA synthetase B5 domain; Region: B5; smart00874
1198114010676	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1198114010677	active site
1198114010678	dimer interface [polypeptide binding]; other site
1198114010679	motif 2; other site
1198114010680	motif 3; other site
1198114010681	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1198114010682	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1198114010683	Beta-lactamase; Region: Beta-lactamase; cl17358
1198114010684	Domain of unknown function (DUF4396); Region: DUF4396; pfam14342
1198114010685	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114010686	S-adenosylmethionine binding site [chemical binding]; other site
1198114010687	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114010688	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114010689	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1198114010690	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
1198114010691	Domain of unknown function (DUF377); Region: DUF377; pfam04041
1198114010692	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
1198114010693	active site
1198114010694	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
1198114010695	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1198114010696	ligand binding site [chemical binding]; other site
1198114010697	NAD binding site [chemical binding]; other site
1198114010698	dimerization interface [polypeptide binding]; other site
1198114010699	catalytic site [active]
1198114010700	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
1198114010701	putative L-serine binding site [chemical binding]; other site
1198114010702	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1198114010703	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1198114010704	catalytic residues [active]
1198114010705	putative regulatory protein, FmdB family; Region: CxxC_CxxC_SSSS; TIGR02605
1198114010706	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1198114010707	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1198114010708	GatB domain; Region: GatB_Yqey; smart00845
1198114010709	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1198114010710	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1198114010711	nucleotide binding pocket [chemical binding]; other site
1198114010712	K-X-D-G motif; other site
1198114010713	catalytic site [active]
1198114010714	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1198114010715	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1198114010716	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1198114010717	Dimer interface [polypeptide binding]; other site
1198114010718	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1198114010719	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1198114010720	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1198114010721	MPT binding site; other site
1198114010722	trimer interface [polypeptide binding]; other site
1198114010723	TonB C terminal; Region: TonB_2; pfam13103
1198114010724	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1198114010725	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1198114010726	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1198114010727	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1198114010728	substrate-cofactor binding pocket; other site
1198114010729	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114010730	catalytic residue [active]
1198114010731	SnoaL-like domain; Region: SnoaL_3; pfam13474
1198114010732	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1198114010733	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1198114010734	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010735	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1198114010736	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1198114010737	RNA binding site [nucleotide binding]; other site
1198114010738	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1198114010739	RNA binding site [nucleotide binding]; other site
1198114010740	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1198114010741	RNA binding site [nucleotide binding]; other site
1198114010742	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1198114010743	RNA binding site [nucleotide binding]; other site
1198114010744	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1198114010745	RNA binding site [nucleotide binding]; other site
1198114010746	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1198114010747	RNA binding site [nucleotide binding]; other site
1198114010748	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114010749	M28 Zn-Peptidases; Region: M28_like_4; cd08015
1198114010750	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114010751	metal binding site [ion binding]; metal-binding site
1198114010752	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
1198114010753	nucleotide binding site/active site [active]
1198114010754	HIT family signature motif; other site
1198114010755	catalytic residue [active]
1198114010756	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1198114010757	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1198114010758	TolR protein; Region: tolR; TIGR02801
1198114010759	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1198114010760	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1198114010761	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1198114010762	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1198114010763	Protein export membrane protein; Region: SecD_SecF; pfam02355
1198114010764	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1198114010765	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1198114010766	Preprotein translocase subunit; Region: YajC; pfam02699
1198114010767	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1198114010768	KH domain; Region: KH_4; pfam13083
1198114010769	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1198114010770	non-specific DNA binding site [nucleotide binding]; other site
1198114010771	salt bridge; other site
1198114010772	sequence-specific DNA binding site [nucleotide binding]; other site
1198114010773	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1198114010774	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114010775	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114010776	catalytic residue [active]
1198114010777	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1198114010778	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114010779	NAD(P) binding site [chemical binding]; other site
1198114010780	active site
1198114010781	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1198114010782	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1198114010783	dimer interface [polypeptide binding]; other site
1198114010784	active site
1198114010785	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1198114010786	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1198114010787	Queuine tRNA-ribosyltransferase; Region: TGT; pfam01702
1198114010788	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1198114010789	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1198114010790	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1198114010791	sequence-specific DNA binding site [nucleotide binding]; other site
1198114010792	salt bridge; other site
1198114010793	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
1198114010794	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1198114010795	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1198114010796	putative NAD(P) binding site [chemical binding]; other site
1198114010797	putative substrate binding site [chemical binding]; other site
1198114010798	catalytic Zn binding site [ion binding]; other site
1198114010799	structural Zn binding site [ion binding]; other site
1198114010800	dimer interface [polypeptide binding]; other site
1198114010801	short chain dehydrogenase; Provisional; Region: PRK06500
1198114010802	classical (c) SDRs; Region: SDR_c; cd05233
1198114010803	NAD(P) binding site [chemical binding]; other site
1198114010804	active site
1198114010805	short chain dehydrogenase; Provisional; Region: PRK06500
1198114010806	classical (c) SDRs; Region: SDR_c; cd05233
1198114010807	NAD(P) binding site [chemical binding]; other site
1198114010808	active site
1198114010809	Cupin; Region: Cupin_6; pfam12852
1198114010810	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114010811	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1198114010812	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114010813	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1198114010814	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1198114010815	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
1198114010816	active site
1198114010817	catalytic site [active]
1198114010818	Ferritin-like domain; Region: Ferritin_2; pfam13668
1198114010819	Ferritin-like domain; Region: Ferritin_2; pfam13668
1198114010820	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114010821	S-adenosylmethionine binding site [chemical binding]; other site
1198114010822	TadE-like protein; Region: TadE; pfam07811
1198114010823	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010824	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1198114010825	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010826	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
1198114010827	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1198114010828	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1198114010829	CAP-like domain; other site
1198114010830	active site
1198114010831	primary dimer interface [polypeptide binding]; other site
1198114010832	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1198114010833	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1198114010834	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1198114010835	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1198114010836	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1198114010837	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114010838	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114010839	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114010840	PEGA domain; Region: PEGA; pfam08308
1198114010841	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
1198114010842	Peptidase M15; Region: Peptidase_M15_3; cl01194
1198114010843	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1198114010844	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114010845	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114010846	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114010847	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114010848	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1198114010849	Surface antigen; Region: Bac_surface_Ag; pfam01103
1198114010850	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1198114010851	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1198114010852	RDD family; Region: RDD; pfam06271
1198114010853	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1198114010854	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1198114010855	Haem-binding domain; Region: Haem_bd; pfam14376
1198114010856	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1198114010857	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1198114010858	WHG domain; Region: WHG; pfam13305
1198114010859	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1198114010860	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1198114010861	NADP binding site [chemical binding]; other site
1198114010862	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1198114010863	Thioredoxin; Region: Thioredoxin_4; pfam13462
1198114010864	SurA N-terminal domain; Region: SurA_N_3; cl07813
1198114010865	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1198114010866	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1198114010867	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1198114010868	catalytic loop [active]
1198114010869	iron binding site [ion binding]; other site
1198114010870	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1198114010871	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1198114010872	nucleotide binding site [chemical binding]; other site
1198114010873	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_14; cd08355
1198114010874	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1198114010875	metal-dependent hydrolase; Provisional; Region: PRK13291
1198114010876	DinB superfamily; Region: DinB_2; pfam12867
1198114010877	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1198114010878	Cytochrome P450; Region: p450; cl12078
1198114010879	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
1198114010880	co-chaperone HscB; Provisional; Region: hscB; PRK03578
1198114010881	DnaJ domain; Region: DnaJ; pfam00226
1198114010882	HSP70 interaction site [polypeptide binding]; other site
1198114010883	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
1198114010884	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1198114010885	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1198114010886	trimerization site [polypeptide binding]; other site
1198114010887	active site
1198114010888	cysteine desulfurase; Provisional; Region: PRK14012
1198114010889	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1198114010890	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114010891	catalytic residue [active]
1198114010892	Rrf2 family protein; Region: rrf2_super; TIGR00738
1198114010893	Transcriptional regulator; Region: Rrf2; pfam02082
1198114010894	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1198114010895	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1198114010896	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1198114010897	SelR domain; Region: SelR; pfam01641
1198114010898	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1198114010899	homotrimer interaction site [polypeptide binding]; other site
1198114010900	putative active site [active]
1198114010901	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1198114010902	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
1198114010903	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1198114010904	metal ion-dependent adhesion site (MIDAS); other site
1198114010905	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1198114010906	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1198114010907	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1198114010908	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
1198114010909	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114010910	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1198114010911	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1198114010912	Zn2+ binding site [ion binding]; other site
1198114010913	Mg2+ binding site [ion binding]; other site
1198114010914	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1198114010915	synthetase active site [active]
1198114010916	NTP binding site [chemical binding]; other site
1198114010917	metal binding site [ion binding]; metal-binding site
1198114010918	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1198114010919	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1198114010920	Uncharacterized protein conserved in bacteria (DUF2218); Region: DUF2218; cl01424
1198114010921	amidophosphoribosyltransferase; Provisional; Region: PRK09123
1198114010922	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1198114010923	active site
1198114010924	tetramer interface [polypeptide binding]; other site
1198114010925	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1198114010926	active site
1198114010927	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
1198114010928	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1198114010929	dimerization interface [polypeptide binding]; other site
1198114010930	ATP binding site [chemical binding]; other site
1198114010931	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1198114010932	dimerization interface [polypeptide binding]; other site
1198114010933	ATP binding site [chemical binding]; other site
1198114010934	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1198114010935	trimer interface [polypeptide binding]; other site
1198114010936	active site
1198114010937	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1198114010938	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
1198114010939	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1198114010940	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1198114010941	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1198114010942	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1198114010943	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114010944	NAD(P) binding site [chemical binding]; other site
1198114010945	active site
1198114010946	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1198114010947	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1198114010948	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1198114010949	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1198114010950	active site
1198114010951	NTP binding site [chemical binding]; other site
1198114010952	metal binding triad [ion binding]; metal-binding site
1198114010953	antibiotic binding site [chemical binding]; other site
1198114010954	Protein of unknown function DUF86; Region: DUF86; cl01031
1198114010955	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1198114010956	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1198114010957	Walker A motif; other site
1198114010958	ATP binding site [chemical binding]; other site
1198114010959	Walker B motif; other site
1198114010960	arginine finger; other site
1198114010961	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1198114010962	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1198114010963	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1198114010964	minor groove reading motif; other site
1198114010965	helix-hairpin-helix signature motif; other site
1198114010966	substrate binding pocket [chemical binding]; other site
1198114010967	active site
1198114010968	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1198114010969	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1198114010970	motif II; other site
1198114010971	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1198114010972	active site
1198114010973	phosphate binding residues; other site
1198114010974	catalytic residues [active]
1198114010975	Maf-like protein; Region: Maf; pfam02545
1198114010976	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1198114010977	active site
1198114010978	dimer interface [polypeptide binding]; other site
1198114010979	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1198114010980	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1198114010981	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1198114010982	catalytic center binding site [active]
1198114010983	ATP binding site [chemical binding]; other site
1198114010984	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1198114010985	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1198114010986	putative active site [active]
1198114010987	ASRGL1_like domains, a subfamily of the L-Asparaginase type 2-like enzymes. The wider family includes Glycosylasparaginase, Taspase 1 and L-Asparaginase type 2 enzymes. The proenzymes undergo autoproteolytic cleavage before a threonine to generate alpha...; Region: ASRGL1_like; cd04702
1198114010988	catalytic nucleophile [active]
1198114010989	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1198114010990	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1198114010991	active site
1198114010992	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1198114010993	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1198114010994	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1198114010995	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114010996	YceG-like family; Region: YceG; pfam02618
1198114010997	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1198114010998	dimerization interface [polypeptide binding]; other site
1198114010999	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114011000	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114011001	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1198114011002	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1198114011003	alanine racemase; Reviewed; Region: alr; PRK00053
1198114011004	active site
1198114011005	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1198114011006	dimer interface [polypeptide binding]; other site
1198114011007	substrate binding site [chemical binding]; other site
1198114011008	catalytic residues [active]
1198114011009	replicative DNA helicase; Region: DnaB; TIGR00665
1198114011010	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1198114011011	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1198114011012	Walker A motif; other site
1198114011013	ATP binding site [chemical binding]; other site
1198114011014	Walker B motif; other site
1198114011015	DNA binding loops [nucleotide binding]
1198114011016	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1198114011017	GxxExxY protein; Region: GxxExxY; TIGR04256
1198114011018	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1198114011019	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1198114011020	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1198114011021	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
1198114011022	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1198114011023	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1198114011024	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1198114011025	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1198114011026	active site residue [active]
1198114011027	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011028	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011029	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011030	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011031	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114011032	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011033	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1198114011034	GTP1/OBG; Region: GTP1_OBG; pfam01018
1198114011035	Obg GTPase; Region: Obg; cd01898
1198114011036	G1 box; other site
1198114011037	GTP/Mg2+ binding site [chemical binding]; other site
1198114011038	Switch I region; other site
1198114011039	G2 box; other site
1198114011040	G3 box; other site
1198114011041	Switch II region; other site
1198114011042	G4 box; other site
1198114011043	G5 box; other site
1198114011044	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1198114011045	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1198114011046	active site
1198114011047	(T/H)XGH motif; other site
1198114011048	Oligomerisation domain; Region: Oligomerisation; pfam02410
1198114011049	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1198114011050	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1198114011051	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1198114011052	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1198114011053	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011054	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1198114011055	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1198114011056	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1198114011057	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1198114011058	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1198114011059	active site clefts [active]
1198114011060	zinc binding site [ion binding]; other site
1198114011061	dimer interface [polypeptide binding]; other site
1198114011062	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
1198114011063	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1198114011064	M28 Zn-Peptidases; Region: M28_like_4; cd08015
1198114011065	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114011066	metal binding site [ion binding]; metal-binding site
1198114011067	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558
1198114011068	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1198114011069	RuvA N terminal domain; Region: RuvA_N; pfam01330
1198114011070	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1198114011071	phage shock protein A; Region: phageshock_pspA; TIGR02977
1198114011072	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1198114011073	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1198114011074	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1198114011075	non-specific DNA binding site [nucleotide binding]; other site
1198114011076	salt bridge; other site
1198114011077	sequence-specific DNA binding site [nucleotide binding]; other site
1198114011078	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1198114011079	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1198114011080	putative NAD(P) binding site [chemical binding]; other site
1198114011081	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1198114011082	hydrophobic ligand binding site; other site
1198114011083	glucose-6-phosphate 1-dehydrogenase; Provisional; Region: PRK12853
1198114011084	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1198114011085	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1198114011086	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
1198114011087	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1198114011088	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1198114011089	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1198114011090	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1198114011091	G1 box; other site
1198114011092	GTP/Mg2+ binding site [chemical binding]; other site
1198114011093	Switch I region; other site
1198114011094	G2 box; other site
1198114011095	Switch II region; other site
1198114011096	G3 box; other site
1198114011097	G4 box; other site
1198114011098	G5 box; other site
1198114011099	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1198114011100	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
1198114011101	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1198114011102	IHF - DNA interface [nucleotide binding]; other site
1198114011103	IHF dimer interface [polypeptide binding]; other site
1198114011104	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1198114011105	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114011106	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1198114011107	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
1198114011108	active site
1198114011109	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1198114011110	ParB-like nuclease domain; Region: ParBc; pfam02195
1198114011111	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1198114011112	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1198114011113	P-loop; other site
1198114011114	Magnesium ion binding site [ion binding]; other site
1198114011115	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1198114011116	Magnesium ion binding site [ion binding]; other site
1198114011117	Phage Tail Collar Domain; Region: Collar; pfam07484
1198114011118	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1198114011119	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1198114011120	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1198114011121	catalytic triad [active]
1198114011122	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1198114011123	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1198114011124	putative acyl-acceptor binding pocket; other site
1198114011125	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1198114011126	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1198114011127	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1198114011128	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1198114011129	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1198114011130	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1198114011131	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1198114011132	active site
1198114011133	dimer interface [polypeptide binding]; other site
1198114011134	motif 1; other site
1198114011135	motif 2; other site
1198114011136	motif 3; other site
1198114011137	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1198114011138	anticodon binding site; other site
1198114011139	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; pfam10013
1198114011140	Protein of unknown function (DUF3253); Region: DUF3253; pfam11625
1198114011141	membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Region: yidC_nterm; TIGR03593
1198114011142	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1198114011143	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1198114011144	hypothetical protein; Validated; Region: PRK00041
1198114011145	Ribonuclease P; Region: Ribonuclease_P; pfam00825
1198114011146	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1198114011147	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1198114011148	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1198114011149	active site pocket [active]
1198114011150	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011151	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011152	Cupin domain; Region: Cupin_2; cl17218
1198114011153	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
1198114011154	carbohydrate binding site [chemical binding]; other site
1198114011155	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
1198114011156	carbohydrate binding site [chemical binding]; other site
1198114011157	alpha-1,6-glucosidases, pullulanase-type; Region: pullul_strch; TIGR02103
1198114011158	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
1198114011159	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
1198114011160	Ca binding site [ion binding]; other site
1198114011161	active site
1198114011162	catalytic site [active]
1198114011163	Domain of unknown function (DUF3372); Region: DUF3372; pfam11852
1198114011164	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1198114011165	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1198114011166	Histidine kinase; Region: HisKA_3; pfam07730
1198114011167	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114011168	ATP binding site [chemical binding]; other site
1198114011169	Mg2+ binding site [ion binding]; other site
1198114011170	G-X-G motif; other site
1198114011171	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114011172	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114011173	active site
1198114011174	phosphorylation site [posttranslational modification]
1198114011175	intermolecular recognition site; other site
1198114011176	dimerization interface [polypeptide binding]; other site
1198114011177	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114011178	DNA binding residues [nucleotide binding]
1198114011179	dimerization interface [polypeptide binding]; other site
1198114011180	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114011181	peptidase domain interface [polypeptide binding]; other site
1198114011182	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114011183	active site
1198114011184	catalytic triad [active]
1198114011185	calcium binding site [ion binding]; other site
1198114011186	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1198114011187	H+ Antiporter protein; Region: 2A0121; TIGR00900
1198114011188	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114011189	putative substrate translocation pore; other site
1198114011190	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114011191	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
1198114011192	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1198114011193	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1198114011194	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1198114011195	Family description; Region: VCBS; pfam13517
1198114011196	Family description; Region: VCBS; pfam13517
1198114011197	Family description; Region: VCBS; pfam13517
1198114011198	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
1198114011199	classical (c) SDRs; Region: SDR_c; cd05233
1198114011200	NAD(P) binding site [chemical binding]; other site
1198114011201	active site
1198114011202	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1198114011203	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
1198114011204	Beta-galactosidase jelly roll domain; Region: BetaGal_dom4_5; pfam13364
1198114011205	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1198114011206	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1198114011207	FAD binding domain; Region: FAD_binding_4; pfam01565
1198114011208	Berberine and berberine like; Region: BBE; pfam08031
1198114011209	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1198114011210	dihydroorotase; Provisional; Region: PRK09237
1198114011211	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114011212	active site
1198114011213	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114011214	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1198114011215	catalytic residue [active]
1198114011216	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1198114011217	homotrimer interaction site [polypeptide binding]; other site
1198114011218	putative active site [active]
1198114011219	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1198114011220	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
1198114011221	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011222	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011223	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1198114011224	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114011225	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114011226	active site
1198114011227	phosphorylation site [posttranslational modification]
1198114011228	intermolecular recognition site; other site
1198114011229	dimerization interface [polypeptide binding]; other site
1198114011230	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114011231	DNA binding residues [nucleotide binding]
1198114011232	dimerization interface [polypeptide binding]; other site
1198114011233	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1198114011234	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1198114011235	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1198114011236	Histidine kinase; Region: HisKA_3; pfam07730
1198114011237	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114011238	ATP binding site [chemical binding]; other site
1198114011239	Mg2+ binding site [ion binding]; other site
1198114011240	G-X-G motif; other site
1198114011241	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114011242	D-galactonate transporter; Region: 2A0114; TIGR00893
1198114011243	putative substrate translocation pore; other site
1198114011244	Uncharacterized conserved protein [Function unknown]; Region: COG3538
1198114011245	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
1198114011246	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1198114011247	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
1198114011248	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1198114011249	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1198114011250	Sel1-like repeats; Region: SEL1; smart00671
1198114011251	Sel1-like repeats; Region: SEL1; smart00671
1198114011252	Sel1-like repeats; Region: SEL1; smart00671
1198114011253	alpha-galactosidase; Region: PLN02808; cl17638
1198114011254	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011255	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
1198114011256	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
1198114011257	MOFRL family; Region: MOFRL; pfam05161
1198114011258	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1198114011259	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1198114011260	DNA-binding site [nucleotide binding]; DNA binding site
1198114011261	FCD domain; Region: FCD; pfam07729
1198114011262	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1198114011263	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114011264	putative substrate translocation pore; other site
1198114011265	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
1198114011266	active site
1198114011267	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011268	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
1198114011269	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011270	Family description; Region: VCBS; pfam13517
1198114011271	Family description; Region: VCBS; pfam13517
1198114011272	Family description; Region: VCBS; pfam13517
1198114011273	Family description; Region: VCBS; pfam13517
1198114011274	Family description; Region: VCBS; pfam13517
1198114011275	Family description; Region: VCBS; pfam13517
1198114011276	Family description; Region: VCBS; pfam13517
1198114011277	Family description; Region: VCBS; pfam13517
1198114011278	Family description; Region: VCBS; pfam13517
1198114011279	Family description; Region: VCBS; pfam13517
1198114011280	Family description; Region: VCBS; pfam13517
1198114011281	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
1198114011282	peptidase domain interface [polypeptide binding]; other site
1198114011283	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
1198114011284	active site
1198114011285	catalytic triad [active]
1198114011286	calcium binding site [ion binding]; other site
1198114011287	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114011288	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114011289	DNA binding site [nucleotide binding]
1198114011290	TPR repeat; Region: TPR_11; pfam13414
1198114011291	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114011292	binding surface
1198114011293	TPR motif; other site
1198114011294	Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilF; COG3063
1198114011295	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114011296	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114011297	Amidohydrolase; Region: Amidohydro_4; pfam13147
1198114011298	active site
1198114011299	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
1198114011300	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011301	PAS domain S-box; Region: sensory_box; TIGR00229
1198114011302	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1198114011303	putative active site [active]
1198114011304	heme pocket [chemical binding]; other site
1198114011305	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1198114011306	Histidine kinase; Region: HisKA_3; pfam07730
1198114011307	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114011308	ATP binding site [chemical binding]; other site
1198114011309	Mg2+ binding site [ion binding]; other site
1198114011310	G-X-G motif; other site
1198114011311	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1198114011312	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114011313	active site
1198114011314	phosphorylation site [posttranslational modification]
1198114011315	intermolecular recognition site; other site
1198114011316	dimerization interface [polypeptide binding]; other site
1198114011317	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1198114011318	DNA binding residues [nucleotide binding]
1198114011319	dimerization interface [polypeptide binding]; other site
1198114011320	Glycoside hydrolase family 94 N-terminal-like domain of uncharacterized function; Region: GH94N_like_1; cd11747
1198114011321	homodimer interface [polypeptide binding]; other site
1198114011322	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1198114011323	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011324	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
1198114011325	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114011326	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1198114011327	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1198114011328	Bacterial transcriptional regulator; Region: IclR; pfam01614
1198114011329	Domain of unknown function (DUF2437); Region: DUF2437; pfam10370
1198114011330	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
1198114011331	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1198114011332	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1198114011333	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1198114011334	metal binding site [ion binding]; metal-binding site
1198114011335	substrate binding pocket [chemical binding]; other site
1198114011336	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1198114011337	classical (c) SDRs; Region: SDR_c; cd05233
1198114011338	NAD(P) binding site [chemical binding]; other site
1198114011339	active site
1198114011340	short chain dehydrogenase; Provisional; Region: PRK08628
1198114011341	classical (c) SDRs; Region: SDR_c; cd05233
1198114011342	NAD(P) binding site [chemical binding]; other site
1198114011343	active site
1198114011344	Amidohydrolase; Region: Amidohydro_2; pfam04909
1198114011345	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1198114011346	Transposase; Region: HTH_Tnp_1; pfam01527
1198114011347	putative transposase OrfB; Reviewed; Region: PHA02517
1198114011348	HTH-like domain; Region: HTH_21; pfam13276
1198114011349	Integrase core domain; Region: rve; pfam00665
1198114011350	Integrase core domain; Region: rve_3; pfam13683
1198114011351	Alpha amylase catalytic domain found in archaeal and bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_arch_bac_AmyA; cd11313
1198114011352	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1198114011353	active site
1198114011354	catalytic site [active]
1198114011355	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011356	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011357	potential frameshift: common BLAST hit: gi|320107933|ref|YP_004183523.1| transcriptional regulator CadC
1198114011358	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114011359	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114011360	DNA binding site [nucleotide binding]
1198114011361	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1198114011362	nudix motif; other site
1198114011363	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
1198114011364	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114011365	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1198114011366	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114011367	Winged helix-turn helix; Region: HTH_29; pfam13551
1198114011368	Homeodomain-like domain; Region: HTH_32; pfam13565
1198114011369	Integrase core domain; Region: rve; pfam00665
1198114011370	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1198114011371	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
1198114011372	Chain length determinant protein; Region: Wzz; pfam02706
1198114011373	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsE; COG3524
1198114011374	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1198114011375	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1198114011376	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
1198114011377	SLBB domain; Region: SLBB; pfam10531
1198114011378	SLBB domain; Region: SLBB; pfam10531
1198114011379	SLBB domain; Region: SLBB; pfam10531
1198114011380	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1198114011381	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1198114011382	Chain length determinant protein; Region: Wzz; pfam02706
1198114011383	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1198114011384	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1198114011385	active site
1198114011386	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114011387	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
1198114011388	Probable Catalytic site; other site
1198114011389	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114011390	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1198114011391	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
1198114011392	Transposase domain (DUF772); Region: DUF772; pfam05598
1198114011393	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1198114011394	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1198114011395	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1198114011396	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1198114011397	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1198114011398	Immunoglobulin I-set domain; Region: I-set; pfam07679
1198114011399	Immunoglobulin like; Region: IG_like; smart00410
1198114011400	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1198114011401	Immunoglobulin domain; Region: Ig; cl11960
1198114011402	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1198114011403	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1198114011404	sugar binding site [chemical binding]; other site
1198114011405	glycosyl hydrolase 64 family; Region: GH64-like; cd09214
1198114011406	substrate binding pocket [chemical binding]; other site
1198114011407	catalytic residues [active]
1198114011408	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1198114011409	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1198114011410	Leucine rich repeat; Region: LRR_8; pfam13855
1198114011411	Leucine rich repeat; Region: LRR_8; pfam13855
1198114011412	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114011413	benzoate transport; Region: 2A0115; TIGR00895
1198114011414	putative substrate translocation pore; other site
1198114011415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1198114011416	Predicted membrane protein [Function unknown]; Region: COG2323
1198114011417	Predicted membrane protein [Function unknown]; Region: COG2323
1198114011418	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1198114011419	dinuclear metal binding motif [ion binding]; other site
1198114011420	Ferritin-like domain; Region: Ferritin_2; pfam13668
1198114011421	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011422	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
1198114011423	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1198114011424	Transposase; Region: HTH_Tnp_1; pfam01527
1198114011425	putative transposase OrfB; Reviewed; Region: PHA02517
1198114011426	HTH-like domain; Region: HTH_21; pfam13276
1198114011427	Integrase core domain; Region: rve; pfam00665
1198114011428	Integrase core domain; Region: rve_3; pfam13683
1198114011429	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
1198114011430	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1198114011431	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
1198114011432	Predicted membrane protein (DUF2306); Region: DUF2306; cl02232
1198114011433	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1198114011434	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1198114011435	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1198114011436	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1198114011437	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1198114011438	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1198114011439	homodimer interface [polypeptide binding]; other site
1198114011440	substrate-cofactor binding pocket; other site
1198114011441	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114011442	catalytic residue [active]
1198114011443	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1198114011444	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1198114011445	homodimer interface [polypeptide binding]; other site
1198114011446	substrate-cofactor binding pocket; other site
1198114011447	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114011448	catalytic residue [active]
1198114011449	Uncharacterized ACR, COG1993; Region: DUF190; cl00872
1198114011450	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1198114011451	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1198114011452	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1198114011453	HlyD family secretion protein; Region: HlyD_3; pfam13437
1198114011454	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1198114011455	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1198114011456	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1198114011457	active site
1198114011458	phosphorylation site [posttranslational modification]
1198114011459	intermolecular recognition site; other site
1198114011460	dimerization interface [polypeptide binding]; other site
1198114011461	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1198114011462	DNA binding site [nucleotide binding]
1198114011463	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1198114011464	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1198114011465	dimer interface [polypeptide binding]; other site
1198114011466	phosphorylation site [posttranslational modification]
1198114011467	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1198114011468	ATP binding site [chemical binding]; other site
1198114011469	Mg2+ binding site [ion binding]; other site
1198114011470	G-X-G motif; other site
1198114011471	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1198114011472	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1198114011473	Outer membrane efflux protein; Region: OEP; pfam02321
1198114011474	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1198114011475	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
1198114011476	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1198114011477	Protein export membrane protein; Region: SecD_SecF; cl14618
1198114011478	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114011479	binding surface
1198114011480	TPR repeat; Region: TPR_11; pfam13414
1198114011481	TPR motif; other site
1198114011482	TPR repeat; Region: TPR_11; pfam13414
1198114011483	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114011484	binding surface
1198114011485	TPR motif; other site
1198114011486	TPR repeat; Region: TPR_11; pfam13414
1198114011487	Transcriptional regulator [Transcription]; Region: PaiB; COG2808
1198114011488	DoxX-like family; Region: DoxX_2; pfam13564
1198114011489	aminotransferase; Validated; Region: PRK08175
1198114011490	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1198114011491	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1198114011492	homodimer interface [polypeptide binding]; other site
1198114011493	catalytic residue [active]
1198114011494	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114011495	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1198114011496	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1198114011497	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1198114011498	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1198114011499	catalytic loop [active]
1198114011500	iron binding site [ion binding]; other site
1198114011501	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1198114011502	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1198114011503	[4Fe-4S] binding site [ion binding]; other site
1198114011504	molybdopterin cofactor binding site; other site
1198114011505	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
1198114011506	molybdopterin cofactor binding site; other site
1198114011507	FdhD/NarQ family; Region: FdhD-NarQ; cl00659
1198114011508	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
1198114011509	bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404
1198114011510	Cupin; Region: Cupin_1; smart00835
1198114011511	Cupin; Region: Cupin_1; smart00835
1198114011512	Topoisomerase IB [DNA replication, recombination, and repair]; Region: COG3569
1198114011513	DNA topoisomerase IB, C-terminal catalytic domain. Topoisomerase I promotes the relaxation of both positive and negative DNA superhelical tension by introducing a transient single-stranded break in duplex DNA. This function is vital for the processes of...; Region: Topo_IB_C; cd00659
1198114011514	active site
1198114011515	DNA binding site [nucleotide binding]
1198114011516	Int/Topo IB signature motif; other site
1198114011517	catalytic residues [active]
1198114011518	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1198114011519	Peptidase family M28; Region: Peptidase_M28; pfam04389
1198114011520	metal binding site [ion binding]; metal-binding site
1198114011521	D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_1; cd07809
1198114011522	N- and C-terminal domain interface [polypeptide binding]; other site
1198114011523	D-xylulose kinase; Region: XylB; TIGR01312
1198114011524	active site
1198114011525	MgATP binding site [chemical binding]; other site
1198114011526	catalytic site [active]
1198114011527	metal binding site [ion binding]; metal-binding site
1198114011528	xylulose binding site [chemical binding]; other site
1198114011529	putative homodimer interface [polypeptide binding]; other site
1198114011530	SnoaL-like domain; Region: SnoaL_2; pfam12680
1198114011531	Protein of unknown function (DUF1634); Region: DUF1634; pfam07843
1198114011532	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1198114011533	bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404
1198114011534	Cupin; Region: Cupin_1; smart00835
1198114011535	Cupin; Region: Cupin_1; smart00835
1198114011536	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1198114011537	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1198114011538	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1198114011539	dimerization interface [polypeptide binding]; other site
1198114011540	substrate binding pocket [chemical binding]; other site
1198114011541	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1198114011542	ROK family; Region: ROK; pfam00480
1198114011543	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1198114011544	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
1198114011545	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1198114011546	xylose isomerase; Region: xylose_isom_A; TIGR02630
1198114011547	xylose isomerase; Provisional; Region: PRK05474
1198114011548	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011549	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1198114011550	active site
1198114011551	Zn binding site [ion binding]; other site
1198114011552	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011553	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011554	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1198114011555	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114011556	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1198114011557	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1198114011558	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114011559	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114011560	ligand binding site [chemical binding]; other site
1198114011561	flexible hinge region; other site
1198114011562	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1198114011563	putative switch regulator; other site
1198114011564	non-specific DNA interactions [nucleotide binding]; other site
1198114011565	DNA binding site [nucleotide binding]
1198114011566	sequence specific DNA binding site [nucleotide binding]; other site
1198114011567	putative cAMP binding site [chemical binding]; other site
1198114011568	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1198114011569	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1198114011570	ligand binding site [chemical binding]; other site
1198114011571	flexible hinge region; other site
1198114011572	precorrin-3B synthase; Region: CobG; TIGR02435
1198114011573	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1198114011574	precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285
1198114011575	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1198114011576	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1198114011577	active site
1198114011578	SAM binding site [chemical binding]; other site
1198114011579	homodimer interface [polypeptide binding]; other site
1198114011580	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1198114011581	active site
1198114011582	SAM binding site [chemical binding]; other site
1198114011583	homodimer interface [polypeptide binding]; other site
1198114011584	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1198114011585	active site
1198114011586	putative homodimer interface [polypeptide binding]; other site
1198114011587	SAM binding site [chemical binding]; other site
1198114011588	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
1198114011589	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1198114011590	S-adenosylmethionine binding site [chemical binding]; other site
1198114011591	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1198114011592	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1198114011593	active site
1198114011594	SAM binding site [chemical binding]; other site
1198114011595	homodimer interface [polypeptide binding]; other site
1198114011596	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1198114011597	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; pfam02571
1198114011598	Precorrin-6A synthase, the cobalamin biosynthesis enzyme CobF; Region: Precorrin-6A-synthase; cd11643
1198114011599	active site
1198114011600	SAM binding site [chemical binding]; other site
1198114011601	homodimer interface [polypeptide binding]; other site
1198114011602	L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434
1198114011603	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1198114011604	Glycosyl transferase 4-like domain; Region: Glyco_trans_4_4; cl17183
1198114011605	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1198114011606	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1198114011607	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1198114011608	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1198114011609	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1198114011610	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
1198114011611	SLBB domain; Region: SLBB; pfam10531
1198114011612	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1198114011613	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1198114011614	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1198114011615	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1198114011616	O-Antigen ligase; Region: Wzy_C; pfam04932
1198114011617	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
1198114011618	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1198114011619	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1198114011620	active site
1198114011621	Putative Ig domain; Region: He_PIG; pfam05345
1198114011622	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1198114011623	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1198114011624	P-loop; other site
1198114011625	Magnesium ion binding site [ion binding]; other site
1198114011626	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
1198114011627	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1198114011628	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
1198114011629	NAD(P) binding site [chemical binding]; other site
1198114011630	active site
1198114011631	short chain dehydrogenase; Provisional; Region: PRK06914
1198114011632	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1198114011633	NADP binding site [chemical binding]; other site
1198114011634	active site
1198114011635	steroid binding site; other site
1198114011636	WHG domain; Region: WHG; pfam13305
1198114011637	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1198114011638	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1198114011639	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1198114011640	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1198114011641	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1198114011642	SnoaL-like domain; Region: SnoaL_2; pfam12680
1198114011643	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114011644	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1198114011645	Amidohydrolase; Region: Amidohydro_4; pfam13147
1198114011646	active site
1198114011647	Doubled CXXCH motif (Paired_CXXCH_1); Region: Paired_CXXCH_1; pfam09699
1198114011648	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1198114011649	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1198114011650	DNA binding site [nucleotide binding]
1198114011651	domain linker motif; other site
1198114011652	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1198114011653	dimerization interface [polypeptide binding]; other site
1198114011654	ligand binding site [chemical binding]; other site
1198114011655	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
1198114011656	active site
1198114011657	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1198114011658	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114011659	binding surface
1198114011660	TPR motif; other site
1198114011661	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114011662	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114011663	binding surface
1198114011664	TPR motif; other site
1198114011665	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114011666	binding surface
1198114011667	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1198114011668	TPR motif; other site
1198114011669	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1198114011670	TPR motif; other site
1198114011671	binding surface
1198114011672	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
1198114011673	decaheme c-type cytochrome, DmsE family; Region: decahem_SO; TIGR03508
1198114011674	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1198114011675	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1198114011676	Family description; Region: VCBS; pfam13517
1198114011677	Family description; Region: VCBS; pfam13517
1198114011678	Family description; Region: VCBS; pfam13517
1198114011679	Family description; Region: VCBS; pfam13517
1198114011680	Family description; Region: VCBS; pfam13517
1198114011681	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1198114011682	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1198114011683	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1198114011684	substrate binding pocket [chemical binding]; other site
1198114011685	catalytic triad [active]
1198114011686	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1198114011687	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1198114011688	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1198114011689	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1198114011690	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1198114011691	Right handed beta helix region; Region: Beta_helix; pfam13229