-- dump date 20140618_191041 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001651051.1 165975458 5851472 2..1486 1 NC_010278.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1486 dnaA 5851472 dnaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosomal replication initiation protein YP_001651051.1 2 D 434271 CDS YP_001651052.1 165975459 5850820 1503..2606 1 NC_010278.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2606 dnaN 5850820 dnaN Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunit beta YP_001651052.1 1503 D 434271 CDS YP_001651053.1 165975460 5851494 2666..3748 1 NC_010278.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3748 recF 5851494 recF Actinobacillus pleuropneumoniae serovar 3 str. JL03 recombination protein F YP_001651053.1 2666 D 434271 CDS YP_001651054.1 165975461 5851514 complement(3804..4376) 1 NC_010278.1 superoxide dismutase Cu-Zn 4376 sodC 5851514 sodC Actinobacillus pleuropneumoniae serovar 3 str. JL03 superoxide dismutase Cu-Zn YP_001651054.1 3804 R 434271 CDS YP_001651055.1 165975462 5851493 4559..5671 1 NC_010278.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 5671 asd 5851493 asd Actinobacillus pleuropneumoniae serovar 3 str. JL03 aspartate-semialdehyde dehydrogenase YP_001651055.1 4559 D 434271 CDS YP_001651056.1 165975463 5851634 complement(5798..6088) 1 NC_010278.1 outer membrane protein P2 6088 ompP2A1 5851634 ompP2A1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein P2 YP_001651056.1 5798 R 434271 CDS YP_001651057.1 165975464 5851704 complement(6113..6928) 1 NC_010278.1 outer membrane protein P2 6928 ompP2A2 5851704 ompP2A2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein P2 YP_001651057.1 6113 R 434271 CDS YP_001651058.1 165975465 5850778 7077..8258 1 NC_010278.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 8258 lpxB 5850778 lpxB Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipid-A-disaccharide synthase YP_001651058.1 7077 D 434271 CDS YP_001651059.1 165975466 5851482 8288..9343 1 NC_010278.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 9343 sohB 5851482 sohB Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative periplasmic protease YP_001651059.1 8288 D 434271 CDS YP_001651060.1 165975467 5851524 9578..10036 1 NC_010278.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 10036 mraZ 5851524 mraZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein MraZ YP_001651060.1 9578 D 434271 CDS YP_001651061.1 165975468 5851430 10062..11003 1 NC_010278.1 S-adenosyl-methyltransferase MraW 11003 mraW 5851430 mraW Actinobacillus pleuropneumoniae serovar 3 str. JL03 S-adenosyl-methyltransferase MraW YP_001651061.1 10062 D 434271 CDS YP_001651062.1 165975469 5851006 11016..11330 1 NC_010278.1 cell division protein 11330 ftsL 5851006 ftsL Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001651062.1 11016 D 434271 CDS YP_001651063.1 165975470 5851557 11334..13394 1 NC_010278.1 penicillin-binding protein 3 13394 ftsI 5851557 ftsI Actinobacillus pleuropneumoniae serovar 3 str. JL03 penicillin-binding protein 3 YP_001651063.1 11334 D 434271 CDS YP_001651064.1 165975471 5851590 13418..14920 1 NC_010278.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 14920 murE 5851590 murE Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001651064.1 13418 D 434271 CDS YP_001651065.1 165975472 5851589 15135..16529 1 NC_010278.1 UDP-MurNAc-pentapeptide synthetase 16529 murF 5851589 murF Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-MurNAc-pentapeptide synthetase YP_001651065.1 15135 D 434271 CDS YP_001651066.1 165975473 5851572 16634..17716 1 NC_010278.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 17716 mraY 5851572 mraY Actinobacillus pleuropneumoniae serovar 3 str. JL03 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001651066.1 16634 D 434271 CDS YP_001651067.1 165975474 5851577 17800..19110 1 NC_010278.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 19110 murD 5851577 murD Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001651067.1 17800 D 434271 CDS YP_001651068.1 165975475 5851523 19112..20290 1 NC_010278.1 cell division protein 20290 ftsW 5851523 ftsW Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001651068.1 19112 D 434271 CDS YP_001651069.1 165975476 5851601 20445..21500 1 NC_010278.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 21500 murG 5851601 murG Actinobacillus pleuropneumoniae serovar 3 str. JL03 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001651069.1 20445 D 434271 CDS YP_001651070.1 165975477 5851348 21552..22979 1 NC_010278.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 22979 murC 5851348 murC Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetylmuramate--L-alanine ligase YP_001651070.1 21552 D 434271 CDS YP_001651071.1 165975478 5851576 23087..23998 1 NC_010278.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 23998 ddl 5851576 ddl Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-alanine--D-alanine ligase YP_001651071.1 23087 D 434271 CDS YP_001651072.1 165975479 5851022 24103..24792 1 NC_010278.1 cell division protein 24792 ftsQ 5851022 ftsQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001651072.1 24103 D 434271 CDS YP_001651073.1 165975480 5851222 24818..26092 1 NC_010278.1 cell division protein 26092 ftsA 5851222 ftsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001651073.1 24818 D 434271 CDS YP_001651074.1 165975481 5850794 26131..27309 1 NC_010278.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 27309 ftsZ 5850794 ftsZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein FtsZ YP_001651074.1 26131 D 434271 CDS YP_001651075.1 165975482 5850984 27377..28297 1 NC_010278.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 28297 lpxC 5850984 lpxC Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001651075.1 27377 D 434271 CDS YP_001651076.1 165975483 5851667 28384..30132 1 NC_010278.1 DNA repair protein 30132 recN 5851667 recN Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA repair protein YP_001651076.1 28384 D 434271 CDS YP_001651077.1 165975484 5851339 complement(30274..31677) 1 NC_010278.1 peptide transport system ATP-binding protein 31677 5851339 APJL_0027 Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide transport system ATP-binding protein YP_001651077.1 30274 R 434271 CDS YP_001651078.1 165975485 5851503 complement(31677..32462) 1 NC_010278.1 nickel transport system permease 32462 5851503 APJL_0028 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nickel transport system permease YP_001651078.1 31677 R 434271 CDS YP_001651079.1 165975486 5851005 complement(32465..33412) 1 NC_010278.1 glutathione permease 33412 gsiC 5851005 gsiC Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutathione permease YP_001651079.1 32465 R 434271 CDS YP_001651080.1 165975487 5850825 complement(33506..35080) 1 NC_010278.1 dipeptide ABC transporter periplasmic protein 35080 5850825 APJL_0030 Actinobacillus pleuropneumoniae serovar 3 str. JL03 dipeptide ABC transporter periplasmic protein YP_001651080.1 33506 R 434271 CDS YP_001651081.1 165975488 5851529 complement(35274..36854) 1 NC_010278.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 36854 prfC 5851529 prfC Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide chain release factor 3 YP_001651081.1 35274 R 434271 CDS YP_001651082.1 165975489 5851499 37037..37504 1 NC_010278.1 membrane protein 37504 5851499 APJL_0032 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane protein YP_001651082.1 37037 D 434271 CDS YP_001651083.1 165975490 5850845 37551..38066 1 NC_010278.1 membrane protein 38066 5850845 APJL_0033 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane protein YP_001651083.1 37551 D 434271 CDS YP_001651084.1 165975491 5851033 38193..38777 1 NC_010278.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 38777 pth 5851033 pth Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptidyl-tRNA hydrolase YP_001651084.1 38193 D 434271 CDS YP_001651085.1 165975492 5851988 38886..39977 1 NC_010278.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 39977 engD 5851988 engD Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTP-dependent nucleic acid-binding protein EngD YP_001651085.1 38886 D 434271 CDS YP_001651086.1 165975493 5851124 40049..40486 1 NC_010278.1 putative protein-S-isoprenylcysteine methyltransferase 40486 5851124 APJL_0036 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative protein-S-isoprenylcysteine methyltransferase YP_001651086.1 40049 D 434271 CDS YP_001651087.1 165975494 5851127 complement(40536..40811) 1 NC_010278.1 hypothetical protein 40811 5851127 APJL_0037 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651087.1 40536 R 434271 CDS YP_001651088.1 165975495 5851571 complement(40842..41306) 1 NC_010278.1 outer membrane lipoprotein 41306 lpp 5851571 lpp Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane lipoprotein YP_001651088.1 40842 R 434271 CDS YP_001651089.1 165975496 5851976 complement(41333..41929) 1 NC_010278.1 hypothetical protein 41929 5851976 APJL_0039 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651089.1 41333 R 434271 CDS YP_001651090.1 165975497 5852077 42108..43754 1 NC_010278.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 43754 argS 5852077 argS Actinobacillus pleuropneumoniae serovar 3 str. JL03 arginyl-tRNA synthetase YP_001651090.1 42108 D 434271 CDS YP_001651091.1 165975498 5852064 43898..45073 1 NC_010278.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 45073 obgE 5852064 obgE Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTPase ObgE YP_001651091.1 43898 D 434271 CDS YP_001651092.1 165975499 5852062 45148..45759 1 NC_010278.1 hypothetical protein 45759 5852062 APJL_0042 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651092.1 45148 D 434271 CDS YP_001651093.1 165975500 5852116 complement(45859..46602) 1 NC_010278.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 46602 5852116 APJL_0043 Actinobacillus pleuropneumoniae serovar 3 str. JL03 23S rRNA (guanosine-2'-O-)-methyltransferase YP_001651093.1 45859 R 434271 CDS YP_001651094.1 165975501 5852085 complement(46681..48045) 1 NC_010278.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 48045 pssA 5852085 pssA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphatidylserine synthase YP_001651094.1 46681 R 434271 CDS YP_001651095.1 165975502 5852093 complement(48197..50965) 1 NC_010278.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 50965 ileS 5852093 ileS Actinobacillus pleuropneumoniae serovar 3 str. JL03 isoleucyl-tRNA synthetase YP_001651095.1 48197 R 434271 CDS YP_001651096.1 165975503 5852096 complement(51074..52036) 1 NC_010278.1 riboflavin biosynthesis protein 52036 ribF 5852096 ribF Actinobacillus pleuropneumoniae serovar 3 str. JL03 riboflavin biosynthesis protein YP_001651096.1 51074 R 434271 CDS YP_001651097.1 165975504 5852791 52369..53649 1 NC_010278.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 53649 nadR 5852791 nadR Actinobacillus pleuropneumoniae serovar 3 str. JL03 nicotinamide-nucleotide adenylyltransferase YP_001651097.1 52369 D 434271 CDS YP_001651098.1 165975505 5852794 53646..54344 1 NC_010278.1 diadenosine tetraphosphatase and related serine/threonine protein phosphatase 54344 5852794 APJL_0048 Actinobacillus pleuropneumoniae serovar 3 str. JL03 diadenosine tetraphosphatase and related serine/threonine protein phosphatase YP_001651098.1 53646 D 434271 CDS YP_001651099.1 165975506 5852795 54517..55233 1 NC_010278.1 two-component response regulator 55233 arcA 5852795 arcA Actinobacillus pleuropneumoniae serovar 3 str. JL03 two-component response regulator YP_001651099.1 54517 D 434271 CDS YP_001651100.1 165975507 5852253 55285..55803 1 NC_010278.1 hypothetical protein 55803 5852253 APJL_0050 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651100.1 55285 D 434271 CDS YP_001651101.1 165975508 5851020 complement(55886..56422) 1 NC_010278.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 56422 5851020 APJL_0051 Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_001651101.1 55886 R 434271 CDS YP_001651102.1 165975509 5852358 56477..57172 1 NC_010278.1 hypothetical protein 57172 5852358 APJL_0052 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651102.1 56477 D 434271 CDS YP_001651103.1 165975510 5852477 57319..59211 1 NC_010278.1 GTP-binding protein 59211 typA 5852477 typA Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTP-binding protein YP_001651103.1 57319 D 434271 CDS YP_001651104.1 165975511 5852569 59370..59633 1 NC_010278.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 59633 grxA 5852569 grxA Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutaredoxin YP_001651104.1 59370 D 434271 CDS YP_001651105.1 165975512 5852672 complement(59699..60415) 1 NC_010278.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 60415 rph 5852672 rph Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease PH YP_001651105.1 59699 R 434271 CDS YP_001651106.1 165975513 5852652 60619..61482 1 NC_010278.1 hypothetical protein 61482 5852652 APJL_0056 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651106.1 60619 D 434271 CDS YP_001651107.1 165975514 5852155 61491..62378 1 NC_010278.1 hypothetical protein 62378 5852155 APJL_0057 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651107.1 61491 D 434271 CDS YP_001651108.1 165975515 5852121 complement(62428..62688) 1 NC_010278.1 ferredoxin-like protein 62688 fdx1 5852121 fdx1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferredoxin-like protein YP_001651108.1 62428 R 434271 CDS YP_001651109.1 165975516 5852812 complement(62834..63463) 1 NC_010278.1 nitrate/nitrite response regulator protein 63463 narP 5852812 narP Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitrate/nitrite response regulator protein YP_001651109.1 62834 R 434271 CDS YP_001651110.1 165975517 5852800 63667..65805 1 NC_010278.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 65805 rlmL 5852800 rlmL Actinobacillus pleuropneumoniae serovar 3 str. JL03 23S rRNA m(2)G2445 methyltransferase YP_001651110.1 63667 D 434271 CDS YP_001651111.1 165975518 5852792 65863..66342 1 NC_010278.1 tRNA/rRNA methyltransferase 66342 5852792 APJL_0061 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA/rRNA methyltransferase YP_001651111.1 65863 D 434271 CDS YP_001651112.1 165975519 5851678 complement(66482..67429) 1 NC_010278.1 transaldolase B 67429 mipB 5851678 mipB Actinobacillus pleuropneumoniae serovar 3 str. JL03 transaldolase B YP_001651112.1 66482 R 434271 CDS YP_001651113.1 165975520 5851579 73587..75182 1 NC_010278.1 dipeptide transport protein 75182 dppA1 5851579 dppA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 dipeptide transport protein YP_001651113.1 73587 D 434271 CDS YP_001651114.1 165975521 5851591 75349..76950 1 NC_010278.1 dipeptide transport protein 76950 dppA2 5851591 dppA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 dipeptide transport protein YP_001651114.1 75349 D 434271 CDS YP_001651115.1 165975522 5851593 77076..78080 1 NC_010278.1 dipeptide transport system permease 78080 dppB 5851593 dppB Actinobacillus pleuropneumoniae serovar 3 str. JL03 dipeptide transport system permease YP_001651115.1 77076 D 434271 CDS YP_001651116.1 165975523 5851598 78158..79048 1 NC_010278.1 dipeptide transport system permease 79048 dppC 5851598 dppC Actinobacillus pleuropneumoniae serovar 3 str. JL03 dipeptide transport system permease YP_001651116.1 78158 D 434271 CDS YP_001651117.1 165975524 5852854 79059..80045 1 NC_010278.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 80045 dppD 5852854 dppD Actinobacillus pleuropneumoniae serovar 3 str. JL03 dipeptide transporter ATP-binding subunit YP_001651117.1 79059 D 434271 CDS YP_001651118.1 165975525 5852796 80058..81047 1 NC_010278.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 81047 dppF 5852796 dppF Actinobacillus pleuropneumoniae serovar 3 str. JL03 dipeptide transporter ATP-binding subunit YP_001651118.1 80058 D 434271 CDS YP_001651119.1 165975526 5852789 complement(81120..81530) 1 NC_010278.1 phosphate-starvation-inducible protein PsiE 81530 psiE1 5852789 psiE1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate-starvation-inducible protein PsiE YP_001651119.1 81120 R 434271 CDS YP_001651120.1 165975527 5852806 complement(81608..82240) 1 NC_010278.1 hypothetical protein 82240 5852806 APJL_0070 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651120.1 81608 R 434271 CDS YP_001651121.1 165975528 5852807 complement(82295..82639) 1 NC_010278.1 hypothetical protein 82639 5852807 APJL_0071 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651121.1 82295 R 434271 CDS YP_001651122.1 165975529 5852786 complement(82726..83763) 1 NC_010278.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 83763 ilvE 5852786 ilvE Actinobacillus pleuropneumoniae serovar 3 str. JL03 branched-chain amino acid aminotransferase YP_001651122.1 82726 R 434271 CDS YP_001651123.1 165975530 5852394 complement(83906..84238) 1 NC_010278.1 glutaredoxin-like protein 84238 5852394 APJL_0073 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutaredoxin-like protein YP_001651123.1 83906 R 434271 CDS YP_001651124.1 165975531 5852506 complement(84310..84975) 1 NC_010278.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 84975 recR 5852506 recR Actinobacillus pleuropneumoniae serovar 3 str. JL03 recombination protein RecR YP_001651124.1 84310 R 434271 CDS YP_001651125.1 165975532 5851686 complement(84986..85315) 1 NC_010278.1 hypothetical protein 85315 5851686 APJL_0075 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651125.1 84986 R 434271 CDS YP_001651126.1 165975533 5852741 complement(85484..86218) 1 NC_010278.1 TobB energy transducing protein 86218 tonB2 5852741 tonB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 TobB energy transducing protein YP_001651126.1 85484 R 434271 CDS YP_001651127.1 165975534 5852777 complement(86351..86740) 1 NC_010278.1 biopolymer transport protein 86740 exbD2 5852777 exbD2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 biopolymer transport protein YP_001651127.1 86351 R 434271 CDS YP_001651128.1 165975535 5852100 complement(86785..87228) 1 NC_010278.1 biopolymer transport protein 87228 exbB2 5852100 exbB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 biopolymer transport protein YP_001651128.1 86785 R 434271 CDS YP_001651129.1 165975536 5852083 87425..87751 1 NC_010278.1 rhodanese-related sulfur transferase 87751 pspE 5852083 pspE Actinobacillus pleuropneumoniae serovar 3 str. JL03 rhodanese-related sulfur transferase YP_001651129.1 87425 D 434271 CDS YP_001651130.1 165975537 5852040 87795..88640 1 NC_010278.1 thioredoxin-like protein 88640 5852040 APJL_0080 Actinobacillus pleuropneumoniae serovar 3 str. JL03 thioredoxin-like protein YP_001651130.1 87795 D 434271 CDS YP_001651131.1 165975538 5852047 complement(88714..89121) 1 NC_010278.1 PTS system mannnose-specific transporter subunit IIA 89121 dhaM 5852047 dhaM Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system mannnose-specific transporter subunit IIA YP_001651131.1 88714 R 434271 CDS YP_001651132.1 165975539 5852009 complement(89130..89756) 1 NC_010278.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 89756 dAK1 5852009 dAK1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydroxyacetone kinase subunit DhaL YP_001651132.1 89130 R 434271 CDS YP_001651133.1 165975540 5851692 complement(89758..90828) 1 NC_010278.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 90828 dhaK 5851692 dhaK Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydroxyacetone kinase subunit DhaK YP_001651133.1 89758 R 434271 CDS YP_001651134.1 165975541 5852819 90998..91951 1 NC_010278.1 thioredoxin reductase 91951 trxB 5852819 trxB Actinobacillus pleuropneumoniae serovar 3 str. JL03 thioredoxin reductase YP_001651134.1 90998 D 434271 CDS YP_001651135.1 165975542 5852820 92059..92811 1 NC_010278.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 92811 kdsB 5852820 kdsB Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-deoxy-manno-octulosonate cytidylyltransferase YP_001651135.1 92059 D 434271 CDS YP_001651136.1 165975543 5851979 92935..93360 1 NC_010278.1 hypothetical protein 93360 5851979 APJL_0086 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651136.1 92935 D 434271 CDS YP_001651137.1 165975544 5851963 complement(93433..94203) 1 NC_010278.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 94203 nudC 5851963 nudC Actinobacillus pleuropneumoniae serovar 3 str. JL03 NADH pyrophosphatase YP_001651137.1 93433 R 434271 CDS YP_001651138.1 165975545 5851574 complement(94221..94916) 1 NC_010278.1 pseudouridylate synthase 94916 rluB 5851574 rluB Actinobacillus pleuropneumoniae serovar 3 str. JL03 pseudouridylate synthase YP_001651138.1 94221 R 434271 CDS YP_001651139.1 165975546 5851521 complement(94920..95738) 1 NC_010278.1 hypothetical protein 95738 5851521 APJL_0089 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651139.1 94920 R 434271 CDS YP_001651140.1 165975547 5851491 complement(95768..96232) 1 NC_010278.1 hypothetical protein 96232 5851491 APJL_0090 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651140.1 95768 R 434271 CDS YP_001651141.1 165975548 5850967 complement(96255..97637) 1 NC_010278.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 97637 5850967 APJL_0091 Actinobacillus pleuropneumoniae serovar 3 str. JL03 proline dipeptidase YP_001651141.1 96255 R 434271 CDS YP_001651142.1 165975549 5850900 97673..97849 1 NC_010278.1 SirA protein 97849 sirA 5850900 sirA Actinobacillus pleuropneumoniae serovar 3 str. JL03 SirA protein YP_001651142.1 97673 D 434271 CDS YP_001651143.1 165975550 5851541 complement(97899..98339) 1 NC_010278.1 hypothetical protein 98339 5851541 APJL_0093 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651143.1 97899 R 434271 CDS YP_001651144.1 165975551 5851440 complement(98341..98961) 1 NC_010278.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 98961 engB 5851440 engB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosome biogenesis GTP-binding protein YsxC YP_001651144.1 98341 R 434271 CDS YP_001651145.1 165975552 5851412 complement(99243..99659) 1 NC_010278.1 hypothetical protein 99659 5851412 APJL_0095 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651145.1 99243 R 434271 CDS YP_001651146.1 165975553 5851219 complement(99697..100527) 1 NC_010278.1 GufA-like protein 100527 gufA 5851219 gufA Actinobacillus pleuropneumoniae serovar 3 str. JL03 GufA-like protein YP_001651146.1 99697 R 434271 CDS YP_001651147.1 165975554 5850902 complement(100678..102513) 1 NC_010278.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 102513 ilvD 5850902 ilvD Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydroxy-acid dehydratase YP_001651147.1 100678 R 434271 CDS YP_001651148.1 165975555 5851474 complement(102631..102849) 1 NC_010278.1 acetolactate synthase 2 regulatory subunit 102849 ilvM 5851474 ilvM Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetolactate synthase 2 regulatory subunit YP_001651148.1 102631 R 434271 CDS YP_001651149.1 165975556 5851476 complement(102867..104519) 1 NC_010278.1 acetohydroxy acid synthase II large subunit 104519 ilvG 5851476 ilvG Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetohydroxy acid synthase II large subunit YP_001651149.1 102867 R 434271 CDS YP_001651150.1 165975557 5851487 104918..106426 1 NC_010278.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 106426 nrfA 5851487 nrfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c552 YP_001651150.1 104918 D 434271 CDS YP_001651151.1 165975558 5851706 106447..107094 1 NC_010278.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 107094 nrfB 5851706 nrfB Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c nitrite reductase pentaheme subunit YP_001651151.1 106447 D 434271 CDS YP_001651152.1 165975559 5851705 107094..107771 1 NC_010278.1 nitrate reductase, Fe-S protein 107771 nrfC 5851705 nrfC Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitrate reductase, Fe-S protein YP_001651152.1 107094 D 434271 CDS YP_001651153.1 165975560 5851356 107771..108739 1 NC_010278.1 nitrate reductase, transmembrane protein 108739 nrfD 5851356 nrfD Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitrate reductase, transmembrane protein YP_001651153.1 107771 D 434271 CDS YP_001651154.1 165975561 5851690 complement(121391..122620) 1 NC_010278.1 uracil permease 122620 uraA 5851690 uraA Actinobacillus pleuropneumoniae serovar 3 str. JL03 uracil permease YP_001651154.1 121391 R 434271 CDS YP_001651155.1 165975562 5851486 complement(122779..126384) 1 NC_010278.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 126384 putA 5851486 putA Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_001651155.1 122779 R 434271 CDS YP_001651156.1 165975563 5851507 complement(126487..128001) 1 NC_010278.1 sodium/proline symporter, proline permease 128001 putP 5851507 putP Actinobacillus pleuropneumoniae serovar 3 str. JL03 sodium/proline symporter, proline permease YP_001651156.1 126487 R 434271 CDS YP_001651157.1 165975564 5851409 complement(128576..129361) 1 NC_010278.1 putative HTH-type transcriptional regulator 129361 5851409 APJL_0109 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative HTH-type transcriptional regulator YP_001651157.1 128576 R 434271 CDS YP_001651158.1 165975565 5851527 complement(129358..129933) 1 NC_010278.1 hypothetical protein 129933 5851527 APJL_0110 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651158.1 129358 R 434271 CDS YP_001651159.1 165975566 5851446 complement(130204..130524) 1 NC_010278.1 hypothetical protein 130524 5851446 APJL_0111 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651159.1 130204 R 434271 CDS YP_001651160.1 165975567 5851135 130602..131153 1 NC_010278.1 hypothetical protein 131153 5851135 APJL_0112 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651160.1 130602 D 434271 CDS YP_001651161.1 165975568 5851531 131259..132323 1 NC_010278.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 132323 hemE 5851531 hemE Actinobacillus pleuropneumoniae serovar 3 str. JL03 uroporphyrinogen decarboxylase YP_001651161.1 131259 D 434271 CDS YP_001651162.1 165975569 5851422 132437..133027 1 NC_010278.1 hypothetical protein 133027 5851422 APJL_0114 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651162.1 132437 D 434271 CDS YP_001651163.1 165975570 5850919 133163..133435 1 NC_010278.1 DNA-binding protein HU 133435 hupA 5850919 hupA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding protein HU YP_001651163.1 133163 D 434271 CDS YP_001651164.1 165975571 5851429 complement(133488..134339) 1 NC_010278.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 134339 thyA 5851429 thyA Actinobacillus pleuropneumoniae serovar 3 str. JL03 thymidylate synthase YP_001651164.1 133488 R 434271 CDS YP_001651165.1 165975572 5851431 134427..135011 1 NC_010278.1 hypothetical protein 135011 5851431 APJL_0117 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651165.1 134427 D 434271 CDS YP_001651166.1 165975573 5851552 135107..136117 1 NC_010278.1 biotin synthetase 136117 bioB 5851552 bioB Actinobacillus pleuropneumoniae serovar 3 str. JL03 biotin synthetase YP_001651166.1 135107 D 434271 CDS YP_001651167.1 165975574 5850713 complement(136181..136390) 1 NC_010278.1 cold shock-like protein 136390 cspC 5850713 cspC Actinobacillus pleuropneumoniae serovar 3 str. JL03 cold shock-like protein YP_001651167.1 136181 R 434271 CDS YP_001651168.1 165975575 5851085 136753..137301 1 NC_010278.1 affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 137301 proQ 5851085 proQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative solute/DNA competence effector YP_001651168.1 136753 D 434271 CDS YP_001651169.1 165975576 5850978 137393..139405 1 NC_010278.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 139405 prc 5850978 prc Actinobacillus pleuropneumoniae serovar 3 str. JL03 carboxy-terminal protease YP_001651169.1 137393 D 434271 CDS YP_001651170.1 165975577 5851223 139502..141067 1 NC_010278.1 hypothetical protein 141067 5851223 APJL_0122 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651170.1 139502 D 434271 CDS YP_001651171.1 165975578 5851528 141239..141793 1 NC_010278.1 hypothetical protein 141793 5851528 APJL_0123 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651171.1 141239 D 434271 CDS YP_001651172.1 165975579 5850722 141811..142440 1 NC_010278.1 glyoxalase II family protein 142440 5850722 APJL_0124 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glyoxalase II family protein YP_001651172.1 141811 D 434271 CDS YP_001651173.1 165975580 5850843 complement(142443..143192) 1 NC_010278.1 hypothetical protein 143192 5850843 APJL_0125 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651173.1 142443 R 434271 CDS YP_001651174.1 165975581 5851018 complement(143189..143563) 1 NC_010278.1 lipoprotein 143563 5851018 APJL_0126 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein YP_001651174.1 143189 R 434271 CDS YP_001651175.1 165975582 5850960 complement(143565..143930) 1 NC_010278.1 HIT-like protein 143930 5850960 APJL_0127 Actinobacillus pleuropneumoniae serovar 3 str. JL03 HIT-like protein YP_001651175.1 143565 R 434271 CDS YP_001651176.1 165975583 5851239 complement(144002..144832) 1 NC_010278.1 iron (chelated) transport system membrane protein 144832 yfeD 5851239 yfeD Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron (chelated) transport system membrane protein YP_001651176.1 144002 R 434271 CDS YP_001651177.1 165975584 5850760 complement(144825..145679) 1 NC_010278.1 iron (chelated) transport system membrane protein 145679 yfeC 5850760 yfeC Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron (chelated) transport system membrane protein YP_001651177.1 144825 R 434271 CDS YP_001651178.1 165975585 5850839 complement(145680..146273) 1 NC_010278.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 146273 rnhB 5850839 rnhB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease HII YP_001651178.1 145680 R 434271 CDS YP_001651179.1 165975586 5851262 complement(146296..147330) 1 NC_010278.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 147330 5851262 APJL_0131 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosome-associated GTPase YP_001651179.1 146296 R 434271 CDS YP_001651180.1 165975587 5851484 147840..148730 1 NC_010278.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 148730 gcvA 5851484 gcvA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding transcriptional activator GcvA YP_001651180.1 147840 D 434271 CDS YP_001651181.1 165975588 5851501 148730..149410 1 NC_010278.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 149410 5851501 APJL_0133 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nucleotidase YP_001651181.1 148730 D 434271 CDS YP_001651182.1 165975589 5851198 149410..150393 1 NC_010278.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 150393 cysB 5851198 cysB Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator CysB YP_001651182.1 149410 D 434271 CDS YP_001651183.1 165975590 5851500 150394..151038 1 NC_010278.1 hypothetical protein 151038 5851500 APJL_0135 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651183.1 150394 D 434271 CDS YP_001651184.1 165975591 5851289 complement(151117..152166) 1 NC_010278.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 152166 ansB 5851289 ansB Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-asparaginase II YP_001651184.1 151117 R 434271 CDS YP_001651185.1 165975592 5851526 152470..154107 1 NC_010278.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 154107 pyrG 5851526 pyrG Actinobacillus pleuropneumoniae serovar 3 str. JL03 CTP synthetase YP_001651185.1 152470 D 434271 CDS YP_001651186.1 165975593 5851362 154207..154713 1 NC_010278.1 hypothetical protein 154713 5851362 APJL_0138 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651186.1 154207 D 434271 CDS YP_001651187.1 165975594 5851361 complement(154759..155361) 1 NC_010278.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 155361 leuD 5851361 leuD Actinobacillus pleuropneumoniae serovar 3 str. JL03 isopropylmalate isomerase small subunit YP_001651187.1 154759 R 434271 CDS YP_001651188.1 165975595 5850717 complement(155372..156781) 1 NC_010278.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 156781 leuC 5850717 leuC Actinobacillus pleuropneumoniae serovar 3 str. JL03 isopropylmalate isomerase large subunit YP_001651188.1 155372 R 434271 CDS YP_001651189.1 165975596 5850959 157123..158238 1 NC_010278.1 hypothetical protein 158238 5850959 APJL_0141 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651189.1 157123 D 434271 CDS YP_001651190.1 165975597 5851437 158366..159628 1 NC_010278.1 hypothetical protein 159628 5851437 APJL_0142 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651190.1 158366 D 434271 CDS YP_001651191.1 165975598 5851522 159639..160772 1 NC_010278.1 glycerate kinase 160772 grk 5851522 grk Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerate kinase YP_001651191.1 159639 D 434271 CDS YP_001651192.1 165975599 5851388 160791..161063 1 NC_010278.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 161063 5851388 APJL_0144 Actinobacillus pleuropneumoniae serovar 3 str. JL03 acylphosphatase YP_001651192.1 160791 D 434271 CDS YP_001651193.1 165975600 5851351 complement(161134..162693) 1 NC_010278.1 ATP-dependent endonuclease 162693 5851351 APJL_0145 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent endonuclease YP_001651193.1 161134 R 434271 CDS YP_001651194.1 165975601 5851360 complement(162697..164076) 1 NC_010278.1 Rossmann fold nucleotide-binding protein 164076 5851360 APJL_0146 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Rossmann fold nucleotide-binding protein YP_001651194.1 162697 R 434271 CDS YP_001651195.1 165975602 5851666 complement(164136..165113) 1 NC_010278.1 tRNA-dihydrouridine synthase A 165113 5851666 APJL_0147 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA-dihydrouridine synthase A YP_001651195.1 164136 R 434271 CDS YP_001651196.1 165975603 5851397 165466..166443 1 NC_010278.1 ribonucleoside-diphosphate reductase subunit beta 1 166443 nrdB_1 5851397 nrdB_1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonucleoside-diphosphate reductase subunit beta 1 YP_001651196.1 165466 D 434271 CDS YP_001651197.1 165975604 5851427 166430..168094 1 NC_010278.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 168094 nrdA_1 5851427 nrdA_1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonucleotide-diphosphate reductase subunit alpha YP_001651197.1 166430 D 434271 CDS YP_001651198.1 165975605 5851573 complement(168229..168828) 1 NC_010278.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 168828 orfG 5851573 orfG Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative DNA uptake protein YP_001651198.1 168229 R 434271 CDS YP_001651199.1 165975606 5851670 169283..170632 1 NC_010278.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 170632 nqrA 5851670 nqrA Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na(+)-translocating NADH-quinone reductase subunit A YP_001651199.1 169283 D 434271 CDS YP_001651200.1 165975607 5851582 170637..171869 1 NC_010278.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 171869 nqrB 5851582 nqrB Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na(+)-translocating NADH-quinone reductase subunit B YP_001651200.1 170637 D 434271 CDS YP_001651201.1 165975608 5851581 171872..172645 1 NC_010278.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 172645 nqrC 5851581 nqrC Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na(+)-translocating NADH-quinone reductase subunit C YP_001651201.1 171872 D 434271 CDS YP_001651202.1 165975609 5851578 172645..173268 1 NC_010278.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 173268 nqrD 5851578 nqrD Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na(+)-translocating NADH-quinone reductase subunit D YP_001651202.1 172645 D 434271 CDS YP_001651203.1 165975610 5851584 173270..173866 1 NC_010278.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 173866 nqrE 5851584 nqrE Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na(+)-translocating NADH-quinone reductase subunit E YP_001651203.1 173270 D 434271 CDS YP_001651204.1 165975611 5851587 173877..175106 1 NC_010278.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 175106 nqrF 5851587 nqrF Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na(+)-translocating NADH-quinone reductase subunit F YP_001651204.1 173877 D 434271 CDS YP_001651205.1 165975612 5851592 175313..176344 1 NC_010278.1 thiamine biosynthesis lipoprotein 176344 apbE 5851592 apbE Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamine biosynthesis lipoprotein YP_001651205.1 175313 D 434271 CDS YP_001651206.1 165975613 5851596 176357..176602 1 NC_010278.1 hypothetical protein 176602 5851596 APJL_0158 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651206.1 176357 D 434271 CDS YP_001651207.1 165975614 5851701 176831..178000 1 NC_010278.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 178000 mnmA 5851701 mnmA Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA-specific 2-thiouridylase MnmA YP_001651207.1 176831 D 434271 CDS YP_001651208.1 165975615 5851597 complement(178073..179227) 1 NC_010278.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 179227 hcaT 5851597 hcaT Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative 3-phenylpropionic acid transporter YP_001651208.1 178073 R 434271 CDS YP_001651209.1 165975616 5851317 complement(179224..180054) 1 NC_010278.1 pyrroline-5-carboxylate reductase 180054 5851317 APJL_0161 Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyrroline-5-carboxylate reductase YP_001651209.1 179224 R 434271 CDS YP_001651210.1 165975617 5851595 180216..181124 1 NC_010278.1 Required for efficient pilin antigenic variation; recombination associated protein 181124 rdgC 5851595 rdgC Actinobacillus pleuropneumoniae serovar 3 str. JL03 recombination associated protein YP_001651210.1 180216 D 434271 CDS YP_001651211.1 165975618 5851594 181134..181739 1 NC_010278.1 phosphatase/phosphohexomutase 181739 5851594 APJL_0163 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphatase/phosphohexomutase YP_001651211.1 181134 D 434271 CDS YP_001651212.1 165975619 5851588 complement(181994..183775) 1 NC_010278.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 183775 5851588 APJL_0164 Actinobacillus pleuropneumoniae serovar 3 str. JL03 anaerobic ribonucleoside triphosphate reductase YP_001651212.1 181994 R 434271 CDS YP_001651213.1 165975620 5851586 complement(183780..184247) 1 NC_010278.1 organic radical activating protein 184247 5851586 APJL_0165 Actinobacillus pleuropneumoniae serovar 3 str. JL03 organic radical activating protein YP_001651213.1 183780 R 434271 CDS YP_001651214.1 165975621 5851583 184629..185210 1 NC_010278.1 Na(+)-translocating NADH-quinone reductase subunit E 185210 rnfA 5851583 rnfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na(+)-translocating NADH-quinone reductase subunit E YP_001651214.1 184629 D 434271 CDS YP_001651215.1 165975622 5851575 185210..185821 1 NC_010278.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 185821 rnfB 5851575 rnfB Actinobacillus pleuropneumoniae serovar 3 str. JL03 electron transport complex protein RnfB YP_001651215.1 185210 D 434271 CDS YP_001651216.1 165975623 5850711 185814..188126 1 NC_010278.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 188126 rnfC 5850711 rnfC Actinobacillus pleuropneumoniae serovar 3 str. JL03 electron transport complex protein RnfC YP_001651216.1 185814 D 434271 CDS YP_001651217.1 165975624 5851357 188119..188763 1 NC_010278.1 membrane protein 188763 5851357 APJL_0169 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane protein YP_001651217.1 188119 D 434271 CDS YP_001651218.1 165975625 5851496 188783..189829 1 NC_010278.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 189829 rnfD 5851496 rnfD Actinobacillus pleuropneumoniae serovar 3 str. JL03 electron transport complex protein RnfD YP_001651218.1 188783 D 434271 CDS YP_001651219.1 165975626 5851428 189829..190461 1 NC_010278.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 190461 rnfG 5851428 rnfG Actinobacillus pleuropneumoniae serovar 3 str. JL03 electron transport complex protein RnfG YP_001651219.1 189829 D 434271 CDS YP_001651220.1 165975627 5851290 190473..191159 1 NC_010278.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 191159 rnfE 5851290 rnfE Actinobacillus pleuropneumoniae serovar 3 str. JL03 electron transport complex protein RsxE YP_001651220.1 190473 D 434271 CDS YP_001651221.1 165975628 5851101 191168..192124 1 NC_010278.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 192124 lpxM 5851101 lpxM Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_001651221.1 191168 D 434271 CDS YP_001651222.1 165975629 5851199 complement(192184..193170) 1 NC_010278.1 hypothetical protein 193170 5851199 APJL_0174 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651222.1 192184 R 434271 CDS YP_001651223.1 165975630 5851063 193612..194577 1 NC_010278.1 thiamine-binding periplasmic protein 194577 tbpA 5851063 tbpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamine-binding periplasmic protein YP_001651223.1 193612 D 434271 CDS YP_001651224.1 165975631 5851169 194784..195233 1 NC_010278.1 dosage-dependent DnaK suppressor protein 195233 dksA 5851169 dksA Actinobacillus pleuropneumoniae serovar 3 str. JL03 dosage-dependent DnaK suppressor protein YP_001651224.1 194784 D 434271 CDS YP_001651225.1 165975632 5850833 195376..196908 1 NC_010278.1 polyA polymerase 196908 pcnB 5850833 pcnB Actinobacillus pleuropneumoniae serovar 3 str. JL03 polyA polymerase YP_001651225.1 195376 D 434271 CDS YP_001651226.1 165975633 5850809 196978..197448 1 NC_010278.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 197448 folK 5850809 folK Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001651226.1 196978 D 434271 CDS YP_001651227.1 165975634 5850926 complement(197483..197704) 1 NC_010278.1 hypothetical protein 197704 5850926 APJL_0179 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651227.1 197483 R 434271 CDS YP_001651228.1 165975635 5851570 complement(197701..200430) 1 NC_010278.1 hypothetical protein 200430 5851570 APJL_0180 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651228.1 197701 R 434271 CDS YP_001651229.1 165975636 5850904 complement(200430..200951) 1 NC_010278.1 hypothetical protein 200951 5850904 APJL_0181 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651229.1 200430 R 434271 CDS YP_001651230.1 165975637 5851321 201352..201759 1 NC_010278.1 lactoylglutathione lyase 201759 gloA1 5851321 gloA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lactoylglutathione lyase YP_001651230.1 201352 D 434271 CDS YP_001651231.1 165975638 5851064 201899..202555 1 NC_010278.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 202555 rnt 5851064 rnt Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease T YP_001651231.1 201899 D 434271 CDS YP_001651232.1 165975639 5851282 complement(202648..203925) 1 NC_010278.1 manganese transporter NRAMP 203925 5851282 APJL_0184 Actinobacillus pleuropneumoniae serovar 3 str. JL03 manganese transporter NRAMP YP_001651232.1 202648 R 434271 CDS YP_001651233.1 165975640 5851308 complement(204501..205622) 1 NC_010278.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 205622 tyrA 5851308 tyrA Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional chorismate mutase/prephenate dehydrogenase YP_001651233.1 204501 R 434271 CDS YP_001651234.1 165975641 5851370 complement(205735..206796) 1 NC_010278.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 206796 aroF 5851370 aroF Actinobacillus pleuropneumoniae serovar 3 str. JL03 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001651234.1 205735 R 434271 CDS YP_001651235.1 165975642 5851342 complement(206838..207884) 1 NC_010278.1 putative glycosyltransferase 207884 5851342 APJL_0187 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative glycosyltransferase YP_001651235.1 206838 R 434271 CDS YP_001651236.1 165975643 5851492 complement(207972..209312) 1 NC_010278.1 pyruvate kinase II 209312 pykA 5851492 pykA Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyruvate kinase II YP_001651236.1 207972 R 434271 CDS YP_001651237.1 165975644 5850817 209543..210034 1 NC_010278.1 phosphohistidine phosphatase 210034 sixA 5850817 sixA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphohistidine phosphatase YP_001651237.1 209543 D 434271 CDS YP_001651238.1 165975645 5850964 210257..211219 1 NC_010278.1 putative dehydrogenase 211219 5850964 APJL_0190 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative dehydrogenase YP_001651238.1 210257 D 434271 CDS YP_001651239.1 165975646 5851327 211247..211543 1 NC_010278.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 211543 fis 5851327 fis Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding protein Fis YP_001651239.1 211247 D 434271 CDS YP_001651240.1 165975647 5850971 complement(211608..212966) 1 NC_010278.1 putative sodium-dependent transporter 212966 5850971 APJL_0192 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sodium-dependent transporter YP_001651240.1 211608 R 434271 CDS YP_001651241.1 165975648 5851975 complement(213031..213864) 1 NC_010278.1 DNA adenine methylase 213864 dam 5851975 dam Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA adenine methylase YP_001651241.1 213031 R 434271 CDS YP_001651242.1 165975649 5851727 complement(213857..214846) 1 NC_010278.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 214846 aroB 5851727 aroB Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-dehydroquinate synthase YP_001651242.1 213857 R 434271 CDS YP_001651243.1 165975650 5851274 complement(215031..215552) 1 NC_010278.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 215552 aroK 5851274 aroK Actinobacillus pleuropneumoniae serovar 3 str. JL03 shikimate kinase YP_001651243.1 215031 R 434271 CDS YP_001651244.1 165975651 5851024 complement(215814..218381) 1 NC_010278.1 penicillin-binding protein 1A 218381 mrcA 5851024 mrcA Actinobacillus pleuropneumoniae serovar 3 str. JL03 penicillin-binding protein 1A YP_001651244.1 215814 R 434271 CDS YP_001651245.1 165975652 5851768 218520..219200 1 NC_010278.1 Tfp pilus assembly protein 219200 5851768 APJL_0197 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Tfp pilus assembly protein YP_001651245.1 218520 D 434271 CDS YP_001651246.1 165975653 5850996 219182..219703 1 NC_010278.1 hypothetical protein 219703 5850996 APJL_0198 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651246.1 219182 D 434271 CDS YP_001651247.1 165975654 5850747 219706..220233 1 NC_010278.1 hypothetical protein 220233 5850747 APJL_0199 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651247.1 219706 D 434271 CDS YP_001651248.1 165975655 5851405 220226..220630 1 NC_010278.1 hypothetical protein 220630 5851405 APJL_0200 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651248.1 220226 D 434271 CDS YP_001651249.1 165975656 5851218 220642..221940 1 NC_010278.1 type II secretory protein 221940 hofQ 5851218 hofQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 type II secretory protein YP_001651249.1 220642 D 434271 CDS YP_001651250.1 165975657 5851032 222066..222479 1 NC_010278.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 222479 nusB 5851032 nusB Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcription antitermination protein NusB YP_001651250.1 222066 D 434271 CDS YP_001651251.1 165975658 5850768 222547..223509 1 NC_010278.1 thiamin-monophosphate kinase 223509 thiL 5850768 thiL Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamin-monophosphate kinase YP_001651251.1 222547 D 434271 CDS YP_001651252.1 165975659 5850982 223522..223995 1 NC_010278.1 phosphatidylglycerophosphatase A 223995 pgpA 5850982 pgpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphatidylglycerophosphatase A YP_001651252.1 223522 D 434271 CDS YP_001651253.1 165975660 5851642 224011..224634 1 NC_010278.1 threonine efflux protein 224634 rhtB 5851642 rhtB Actinobacillus pleuropneumoniae serovar 3 str. JL03 threonine efflux protein YP_001651253.1 224011 D 434271 CDS YP_001651254.1 165975661 5851334 complement(224682..225719) 1 NC_010278.1 putative tRNA/rRNA methyltransferase 225719 5851334 APJL_0206 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative tRNA/rRNA methyltransferase YP_001651254.1 224682 R 434271 CDS YP_001651255.1 165975662 5851164 225894..226697 1 NC_010278.1 inositol-1-monophosphatase 226697 suhB 5851164 suhB Actinobacillus pleuropneumoniae serovar 3 str. JL03 inositol-1-monophosphatase YP_001651255.1 225894 D 434271 CDS YP_001651256.1 165975663 5850977 226818..228671 1 NC_010278.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 228671 dxs 5850977 dxs Actinobacillus pleuropneumoniae serovar 3 str. JL03 1-deoxy-D-xylulose-5-phosphate synthase YP_001651256.1 226818 D 434271 CDS YP_001651257.1 165975664 5851771 complement(228717..229535) 1 NC_010278.1 transposase 229535 5851771 APJL_0209 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001651257.1 228717 R 434271 CDS YP_001651258.1 165975665 5850987 complement(229541..229891) 1 NC_010278.1 transposase and inactivated derivative 229891 5850987 APJL_0210 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001651258.1 229541 R 434271 CDS YP_001651259.1 165975666 5850863 complement(229898..230053) 1 NC_010278.1 transposase and inactivated derivative 230053 5850863 APJL_0211 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001651259.1 229898 R 434271 CDS YP_001651260.1 165975667 5851434 complement(230143..231408) 1 NC_010278.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 231408 glyA 5851434 glyA Actinobacillus pleuropneumoniae serovar 3 str. JL03 serine hydroxymethyltransferase YP_001651260.1 230143 R 434271 CDS YP_001651261.1 165975668 5851413 complement(231639..232526) 1 NC_010278.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 232526 ppnK 5851413 ppnK Actinobacillus pleuropneumoniae serovar 3 str. JL03 inorganic polyphosphate/ATP-NAD kinase YP_001651261.1 231639 R 434271 CDS YP_001651262.1 165975669 5850857 complement(232617..235964) 1 NC_010278.1 helicase 235964 5850857 APJL_0214 Actinobacillus pleuropneumoniae serovar 3 str. JL03 helicase YP_001651262.1 232617 R 434271 CDS YP_001651263.1 165975670 5851055 complement(235961..236917) 1 NC_010278.1 CRISPR-associated protein 236917 cas1 5851055 cas1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 CRISPR-associated protein YP_001651263.1 235961 R 434271 CDS YP_001651264.1 165975671 5851545 complement(239167..239736) 1 NC_010278.1 hypothetical protein 239736 5851545 APJL_0216 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651264.1 239167 R 434271 CDS YP_001651265.1 165975672 5850754 complement(239739..240734) 1 NC_010278.1 CRISPR-associated protein 240734 5850754 APJL_0217 Actinobacillus pleuropneumoniae serovar 3 str. JL03 CRISPR-associated protein YP_001651265.1 239739 R 434271 CDS YP_001651266.1 165975673 5851267 complement(240736..241695) 1 NC_010278.1 CRISPR-associated protein 241695 5851267 APJL_0218 Actinobacillus pleuropneumoniae serovar 3 str. JL03 CRISPR-associated protein YP_001651266.1 240736 R 434271 CDS YP_001651267.1 165975674 5851653 complement(241692..243041) 1 NC_010278.1 CRISPR-associated protein 243041 5851653 APJL_0219 Actinobacillus pleuropneumoniae serovar 3 str. JL03 CRISPR-associated protein YP_001651267.1 241692 R 434271 CDS YP_001651268.1 165975675 5851158 243489..245420 1 NC_010278.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 245420 thrS 5851158 thrS Actinobacillus pleuropneumoniae serovar 3 str. JL03 threonyl-tRNA synthetase YP_001651268.1 243489 D 434271 CDS YP_001651269.1 165975676 5850994 245562..246236 1 NC_010278.1 putative lipoprotein 246236 5850994 APJL_0221 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative lipoprotein YP_001651269.1 245562 D 434271 CDS YP_001651270.1 165975677 5851550 246267..246593 1 NC_010278.1 hypothetical protein 246593 5851550 APJL_0222 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651270.1 246267 D 434271 CDS YP_001651271.1 165975678 5851554 246605..247264 1 NC_010278.1 hypothetical protein 247264 5851554 APJL_0223 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651271.1 246605 D 434271 CDS YP_001651272.1 165975679 5851390 247542..248021 1 NC_010278.1 translation initiation factor IF-3 248021 infC 5851390 infC Actinobacillus pleuropneumoniae serovar 3 str. JL03 translation initiation factor IF-3 YP_001651272.1 247542 D 434271 CDS YP_001651273.1 165975680 5851404 248270..248467 1 NC_010278.1 50S ribosomal protein L35 248467 rpmI 5851404 rpmI Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L35 YP_001651273.1 248270 D 434271 CDS YP_001651274.1 165975681 5851324 248535..248888 1 NC_010278.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 248888 rplT 5851324 rplT Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L20 YP_001651274.1 248535 D 434271 CDS YP_001651275.1 165975682 5851000 248937..249473 1 NC_010278.1 hypothetical protein 249473 5851000 APJL_0227 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651275.1 248937 D 434271 CDS YP_001651276.1 165975683 5851742 249506..249799 1 NC_010278.1 hypothetical protein 249799 5851742 APJL_0228 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651276.1 249506 D 434271 CDS YP_001651277.1 165975684 5851714 249878..250387 1 NC_010278.1 transposase and inactivated derivative 250387 5851714 APJL_0229 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001651277.1 249878 D 434271 CDS YP_001651278.1 165975685 5851058 250393..250716 1 NC_010278.1 putative transposase-like protein 250716 5851058 APJL_0230 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transposase-like protein YP_001651278.1 250393 D 434271 CDS YP_001651279.1 165975686 5851485 250740..250880 1 NC_010278.1 transposase 250880 5851485 APJL_0231 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001651279.1 250740 D 434271 CDS YP_001651280.1 165975687 5850752 250896..251087 1 NC_010278.1 transposase 251087 5850752 APJL_0232 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001651280.1 250896 D 434271 CDS YP_001651281.1 165975688 5851247 complement(251135..252430) 1 NC_010278.1 hypothetical protein 252430 5851247 APJL_0233 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651281.1 251135 R 434271 CDS YP_001651282.1 165975689 5851187 complement(252474..253124) 1 NC_010278.1 RNA pseudouridine synthase 253124 rluA 5851187 rluA Actinobacillus pleuropneumoniae serovar 3 str. JL03 RNA pseudouridine synthase YP_001651282.1 252474 R 434271 CDS YP_001651283.1 165975690 5851269 253174..253806 1 NC_010278.1 phosphoglycerate mutase 253806 gpmB 5851269 gpmB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoglycerate mutase YP_001651283.1 253174 D 434271 CDS YP_001651284.1 165975691 5851813 complement(253873..254286) 1 NC_010278.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 254286 5851813 APJL_0236 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Holliday junction resolvase-like protein YP_001651284.1 253873 R 434271 CDS YP_001651285.1 165975692 5851129 complement(254339..254899) 1 NC_010278.1 hypothetical protein 254899 5851129 APJL_0237 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651285.1 254339 R 434271 CDS YP_001651286.1 165975693 5851733 complement(254899..255630) 1 NC_010278.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 255630 5851733 APJL_0238 Actinobacillus pleuropneumoniae serovar 3 str. JL03 16S ribosomal RNA methyltransferase RsmE YP_001651286.1 254899 R 434271 CDS YP_001651287.1 165975694 5851323 complement(255806..256396) 1 NC_010278.1 putative lipoprotein 256396 5851323 APJL_0239 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative lipoprotein YP_001651287.1 255806 R 434271 CDS YP_001651288.1 165975695 5851471 256525..256836 1 NC_010278.1 putative transcriptional regulator 256836 bolA 5851471 bolA Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transcriptional regulator YP_001651288.1 256525 D 434271 CDS YP_001651289.1 165975696 5851401 complement(257229..257603) 1 NC_010278.1 putative lipoprotein 257603 5851401 APJL_0241 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative lipoprotein YP_001651289.1 257229 R 434271 CDS YP_001651290.1 165975697 5851134 complement(257623..257931) 1 NC_010278.1 hypothetical protein 257931 5851134 APJL_0242 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651290.1 257623 R 434271 CDS YP_001651291.1 165975698 5851402 258034..258360 1 NC_010278.1 hypothetical protein 258360 5851402 APJL_0243 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651291.1 258034 D 434271 CDS YP_001651292.1 165975699 5851188 258469..261186 1 NC_010278.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 261186 secA 5851188 secA Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit SecA YP_001651292.1 258469 D 434271 CDS YP_001651293.1 165975700 5851655 261316..262503 1 NC_010278.1 FOG: TPR repeat; hypothetical protein 262503 5851655 APJL_0245 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651293.1 261316 D 434271 CDS YP_001651294.1 165975701 5851646 262500..262898 1 NC_010278.1 mutator MutT protein 262898 mutT1 5851646 mutT1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 mutator MutT protein YP_001651294.1 262500 D 434271 CDS YP_001651295.1 165975702 5851457 263133..264086 1 NC_010278.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 264086 argC 5851457 argC Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetyl-gamma-glutamyl-phosphate reductase YP_001651295.1 263133 D 434271 CDS YP_001651296.1 165975703 5851082 264107..264961 1 NC_010278.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 264961 argB 5851082 argB Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetylglutamate kinase YP_001651296.1 264107 D 434271 CDS YP_001651297.1 165975704 5851417 264975..266156 1 NC_010278.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 266156 argD2 5851417 argD2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetylornithine aminotransferase YP_001651297.1 264975 D 434271 CDS YP_001651298.1 165975705 5850995 266370..268079 1 NC_010278.1 transferrin-binding protein 2 268079 tbpB2 5850995 tbpB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transferrin-binding protein 2 YP_001651298.1 266370 D 434271 CDS YP_001651299.1 165975706 5851649 complement(270930..272192) 1 NC_010278.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 272192 rho 5851649 rho Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcription termination factor Rho YP_001651299.1 270930 R 434271 CDS YP_001651300.1 165975707 5851389 complement(272390..273340) 1 NC_010278.1 cysteine synthase 273340 cysK 5851389 cysK Actinobacillus pleuropneumoniae serovar 3 str. JL03 cysteine synthase YP_001651300.1 272390 R 434271 CDS YP_001651301.1 165975708 5851295 complement(273552..274502) 1 NC_010278.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 274502 thrB 5851295 thrB Actinobacillus pleuropneumoniae serovar 3 str. JL03 homoserine kinase YP_001651301.1 273552 R 434271 CDS YP_001651302.1 165975709 5851780 277366..278007 1 NC_010278.1 manganese superoxide dismutase 278007 sodA 5851780 sodA Actinobacillus pleuropneumoniae serovar 3 str. JL03 manganese superoxide dismutase YP_001651302.1 277366 D 434271 CDS YP_001651303.1 165975710 5851213 complement(278095..279219) 1 NC_010278.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 279219 alr 5851213 alr Actinobacillus pleuropneumoniae serovar 3 str. JL03 alanine racemase YP_001651303.1 278095 R 434271 CDS YP_001651304.1 165975711 5851002 279340..281259 1 NC_010278.1 exodeoxyribonuclease V subunit alpha 281259 recD 5851002 recD Actinobacillus pleuropneumoniae serovar 3 str. JL03 exodeoxyribonuclease V subunit alpha YP_001651304.1 279340 D 434271 CDS YP_001651305.1 165975712 5851761 complement(287144..288721) 1 NC_010278.1 aminoacyl-histidine dipeptidase 288721 pepD 5851761 pepD Actinobacillus pleuropneumoniae serovar 3 str. JL03 aminoacyl-histidine dipeptidase YP_001651305.1 287144 R 434271 CDS YP_001651306.1 165975713 5851722 288771..289244 1 NC_010278.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 289244 gpt 5851722 gpt Actinobacillus pleuropneumoniae serovar 3 str. JL03 xanthine-guanine phosphoribosyltransferase YP_001651306.1 288771 D 434271 CDS YP_001651307.1 165975714 5851236 289328..289948 1 NC_010278.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 289948 gmk 5851236 gmk Actinobacillus pleuropneumoniae serovar 3 str. JL03 guanylate kinase YP_001651307.1 289328 D 434271 CDS YP_001651308.1 165975715 5852025 290050..291444 1 NC_010278.1 outer membrane protein 291444 5852025 APJL_0265 Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein YP_001651308.1 290050 D 434271 CDS YP_001651309.1 165975716 5851836 complement(291492..291788) 1 NC_010278.1 hypothetical protein 291788 5851836 APJL_0266 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651309.1 291492 R 434271 CDS YP_001651310.1 165975717 5851999 complement(291781..292215) 1 NC_010278.1 hypothetical protein 292215 5851999 APJL_0267 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651310.1 291781 R 434271 CDS YP_001651311.1 165975718 5852004 complement(292263..293318) 1 NC_010278.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 293318 modC 5852004 modC Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdate transporter ATP-binding protein YP_001651311.1 292263 R 434271 CDS YP_001651312.1 165975719 5851763 complement(293322..294011) 1 NC_010278.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 294011 modB 5851763 modB Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdate ABC transporter permease YP_001651312.1 293322 R 434271 CDS YP_001651313.1 165975720 5851204 complement(294071..294829) 1 NC_010278.1 molybdate-binding periplasmic protein, ABC transporter 294829 modA 5851204 modA Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdate-binding periplasmic protein, ABC transporter YP_001651313.1 294071 R 434271 CDS YP_001651314.1 165975721 5851153 complement(294925..295686) 1 NC_010278.1 ABC transporter permease 295686 5851153 APJL_0271 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter permease YP_001651314.1 294925 R 434271 CDS YP_001651315.1 165975722 5851073 complement(295690..296598) 1 NC_010278.1 ABC transporter ATP-binding protein 296598 5851073 APJL_0272 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001651315.1 295690 R 434271 CDS YP_001651316.1 165975723 5851315 complement(296598..298664) 1 NC_010278.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 298664 dnaX 5851315 dnaX Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunits gamma and tau YP_001651316.1 296598 R 434271 CDS YP_001651317.1 165975724 5851490 complement(298713..299261) 1 NC_010278.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 299261 apt 5851490 apt Actinobacillus pleuropneumoniae serovar 3 str. JL03 adenine phosphoribosyltransferase YP_001651317.1 298713 R 434271 CDS YP_001651318.1 165975725 5851498 299462..300094 1 NC_010278.1 two-component response regulator involved in C4-dicarboxylate transport 300094 5851498 APJL_0275 Actinobacillus pleuropneumoniae serovar 3 str. JL03 two-component response regulator involved in C4-dicarboxylate transport YP_001651318.1 299462 D 434271 CDS YP_001651319.1 165975726 5851605 300467..301561 1 NC_010278.1 threonine synthase 301561 5851605 APJL_0278 Actinobacillus pleuropneumoniae serovar 3 str. JL03 threonine synthase YP_001651319.1 300467 D 434271 CDS YP_001651320.1 165975727 5851168 301576..302067 1 NC_010278.1 hypothetical protein 302067 5851168 APJL_0279 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651320.1 301576 D 434271 CDS YP_001651321.1 165975728 5851399 complement(302178..302933) 1 NC_010278.1 iron (chelated) transporter, ATP-binding protein 302933 yfeB 5851399 yfeB Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron (chelated) transporter, ATP-binding protein YP_001651321.1 302178 R 434271 CDS YP_001651322.1 165975729 5851313 complement(303899..304252) 1 NC_010278.1 putative sulfite reductase 304252 5851313 APJL_0283 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sulfite reductase YP_001651322.1 303899 R 434271 CDS YP_001651323.1 165975730 5851319 complement(304286..304951) 1 NC_010278.1 transporter 304951 5851319 APJL_0284 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transporter YP_001651323.1 304286 R 434271 CDS YP_001651324.1 165975731 5850756 305133..305684 1 NC_010278.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 305684 pgsA 5850756 pgsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001651324.1 305133 D 434271 CDS YP_001651325.1 165975732 5851335 305804..307774 1 NC_010278.1 iron-regulated outer membrane protein 307774 frpB 5851335 frpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-regulated outer membrane protein YP_001651325.1 305804 D 434271 CDS YP_001651326.1 165975733 5851131 307927..309759 1 NC_010278.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 309759 uvrC 5851131 uvrC Actinobacillus pleuropneumoniae serovar 3 str. JL03 excinuclease ABC subunit C YP_001651326.1 307927 D 434271 CDS YP_001651327.1 165975734 5851447 309828..310580 1 NC_010278.1 TatD family deoxyribonuclease 310580 5851447 APJL_0288 Actinobacillus pleuropneumoniae serovar 3 str. JL03 TatD family deoxyribonuclease YP_001651327.1 309828 D 434271 CDS YP_001651328.1 165975735 5851406 complement(310717..312735) 1 NC_010278.1 ATP-dependent DNA helicase 312735 rep 5851406 rep Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent DNA helicase YP_001651328.1 310717 R 434271 CDS YP_001651329.1 165975736 5851453 313069..314184 1 NC_010278.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 314184 potA 5851453 potA Actinobacillus pleuropneumoniae serovar 3 str. JL03 putrescine/spermidine ABC transporter ATPase YP_001651329.1 313069 D 434271 CDS YP_001651330.1 165975737 5851480 314171..315037 1 NC_010278.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 315037 potB 5851480 potB Actinobacillus pleuropneumoniae serovar 3 str. JL03 spermidine/putrescine ABC transporter membrane protein YP_001651330.1 314171 D 434271 CDS YP_001651331.1 165975738 5850916 315037..315804 1 NC_010278.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 315804 potC 5850916 potC Actinobacillus pleuropneumoniae serovar 3 str. JL03 spermidine/putrescine ABC transporter membrane protein YP_001651331.1 315037 D 434271 CDS YP_001651332.1 165975739 5851520 316686..317570 1 NC_010278.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 317570 ruvB 5851520 ruvB Actinobacillus pleuropneumoniae serovar 3 str. JL03 Holliday junction DNA helicase RuvB YP_001651332.1 316686 D 434271 CDS YP_001651333.1 165975740 5851196 complement(317627..318364) 1 NC_010278.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 318364 ubiG 5851196 ubiG Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-demethylubiquinone-9 3-methyltransferase YP_001651333.1 317627 R 434271 CDS YP_001651334.1 165975741 5851566 318511..321201 1 NC_010278.1 DNA gyrase subunit A 321201 gyrA 5851566 gyrA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA gyrase subunit A YP_001651334.1 318511 D 434271 CDS YP_001651335.1 165975742 5850991 321238..322851 1 NC_010278.1 putative type I restriction-modification systemmethyltransferase subunit 322851 hsdM2 5850991 hsdM2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative type I restriction-modification systemmethyltransferase subunit YP_001651335.1 321238 D 434271 CDS YP_001651336.1 165975743 5850938 322848..323849 1 NC_010278.1 hypothetical protein 323849 5850938 APJL_0299 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651336.1 322848 D 434271 CDS YP_001651337.1 165975744 5851383 324067..324363 1 NC_010278.1 hypothetical protein 324363 5851383 APJL_0300 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651337.1 324067 D 434271 CDS YP_001651338.1 165975745 5850811 324400..324978 1 NC_010278.1 hypothetical protein 324978 5850811 APJL_0301 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651338.1 324400 D 434271 CDS YP_001651339.1 165975746 5851774 325144..326313 1 NC_010278.1 putative type I restriction enzyme specificity protein 326313 5851774 APJL_0302 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative type I restriction enzyme specificity protein YP_001651339.1 325144 D 434271 CDS YP_001651340.1 165975747 5851181 326325..327440 1 NC_010278.1 anticodon nuclease 327440 5851181 APJL_0303 Actinobacillus pleuropneumoniae serovar 3 str. JL03 anticodon nuclease YP_001651340.1 326325 D 434271 CDS YP_001651341.1 165975748 5851512 327447..330584 1 NC_010278.1 type I site-specific deoxyribonuclease 330584 hsdR 5851512 hsdR Actinobacillus pleuropneumoniae serovar 3 str. JL03 type I site-specific deoxyribonuclease YP_001651341.1 327447 D 434271 CDS YP_001651342.1 165975749 5851311 330603..332546 1 NC_010278.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 332546 uup 5851311 uup Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATPase YP_001651342.1 330603 D 434271 CDS YP_001651343.1 165975750 5851602 332546..333310 1 NC_010278.1 hypothetical protein 333310 5851602 APJL_0306 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651343.1 332546 D 434271 CDS YP_001651344.1 165975751 5851285 complement(333389..333721) 1 NC_010278.1 hypothetical protein 333721 5851285 APJL_0307 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651344.1 333389 R 434271 CDS YP_001651345.1 165975752 5851421 334178..335728 1 NC_010278.1 cytochrome D ubiquinol oxidase, subunit I 335728 cydA 5851421 cydA Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome D ubiquinol oxidase, subunit I YP_001651345.1 334178 D 434271 CDS YP_001651346.1 165975753 5851420 335742..336878 1 NC_010278.1 cytochrome D ubiquinol oxidase subunit II 336878 cydB 5851420 cydB Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome D ubiquinol oxidase subunit II YP_001651346.1 335742 D 434271 CDS YP_001651347.1 165975754 5851061 336891..336989 1 NC_010278.1 hypothetical protein 336989 5851061 APJL_0310 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651347.1 336891 D 434271 CDS YP_001651348.1 165975755 5851280 337001..337303 1 NC_010278.1 hypothetical protein 337303 5851280 APJL_0311 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651348.1 337001 D 434271 CDS YP_001651349.1 165975756 5850739 337446..337835 1 NC_010278.1 hypothetical protein 337835 5850739 APJL_0312 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651349.1 337446 D 434271 CDS YP_001651350.1 165975757 5850801 337870..338550 1 NC_010278.1 colicin transport protein 338550 tolQ 5850801 tolQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 colicin transport protein YP_001651350.1 337870 D 434271 CDS YP_001651351.1 165975758 5851318 338629..339069 1 NC_010278.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 339069 tolR 5851318 tolR Actinobacillus pleuropneumoniae serovar 3 str. JL03 colicin uptake protein TolR YP_001651351.1 338629 D 434271 CDS YP_001651352.1 165975759 5850905 339085..340356 1 NC_010278.1 colicin import membrane protein 340356 tolA1 5850905 tolA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 colicin import membrane protein YP_001651352.1 339085 D 434271 CDS YP_001651353.1 165975760 5851364 340374..341654 1 NC_010278.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 341654 tolB 5851364 tolB Actinobacillus pleuropneumoniae serovar 3 str. JL03 translocation protein TolB YP_001651353.1 340374 D 434271 CDS YP_001651354.1 165975761 5850944 341681..342139 1 NC_010278.1 peptidoglycan-associated outer membrane lipoprotein 342139 pal 5850944 pal Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptidoglycan-associated outer membrane lipoprotein YP_001651354.1 341681 D 434271 CDS YP_001651355.1 165975762 5851509 342269..343123 1 NC_010278.1 putative permease 343123 5851509 APJL_0318 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative permease YP_001651355.1 342269 D 434271 CDS YP_001651356.1 165975763 5851340 343203..344063 1 NC_010278.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 344063 djlA 5851340 djlA Actinobacillus pleuropneumoniae serovar 3 str. JL03 Dna-J like membrane chaperone protein YP_001651356.1 343203 D 434271 CDS YP_001651357.1 165975764 5851263 344148..345110 1 NC_010278.1 putative nitrogen regulator protein 345110 5851263 APJL_0320 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative nitrogen regulator protein YP_001651357.1 344148 D 434271 CDS YP_001651358.1 165975765 5851734 345162..346208 1 NC_010278.1 hypothetical protein 346208 5851734 APJL_0321 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651358.1 345162 D 434271 CDS YP_001651359.1 165975766 5851359 complement(346396..348312) 1 NC_010278.1 ABC transporter ATP-binding protein 348312 5851359 APJL_0322 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001651359.1 346396 R 434271 CDS YP_001651360.1 165975767 5851104 348473..348715 1 NC_010278.1 hypothetical protein 348715 5851104 APJL_0323 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651360.1 348473 D 434271 CDS YP_001651361.1 165975768 5850974 350149..350895 1 NC_010278.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 350895 moeB 5850974 moeB Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdopterin biosynthesis protein MoeB YP_001651361.1 350149 D 434271 CDS YP_001651362.1 165975769 5851072 complement(351292..352620) 1 NC_010278.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 352620 rumA 5851072 rumA Actinobacillus pleuropneumoniae serovar 3 str. JL03 23S rRNA 5-methyluridine methyltransferase YP_001651362.1 351292 R 434271 CDS YP_001651363.1 165975770 5851456 352678..354003 1 NC_010278.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 354003 dgt 5851456 dgt Actinobacillus pleuropneumoniae serovar 3 str. JL03 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_001651363.1 352678 D 434271 CDS YP_001651364.1 165975771 5851812 354175..357084 1 NC_010278.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 357084 hepA 5851812 hepA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent helicase HepA YP_001651364.1 354175 D 434271 CDS YP_001651365.1 165975772 5851090 357199..357867 1 NC_010278.1 ribosomal large subunit pseudouridine synthase A 357867 rluA 5851090 rluA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosomal large subunit pseudouridine synthase A YP_001651365.1 357199 D 434271 CDS YP_001651366.1 165975773 5851654 complement(358063..358611) 1 NC_010278.1 N-acetyl-anhydromuranmyl-L-alanine amidase 358611 ampD 5851654 ampD Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetyl-anhydromuranmyl-L-alanine amidase YP_001651366.1 358063 R 434271 CDS YP_001651367.1 165975774 5851635 358751..359593 1 NC_010278.1 hypothetical protein 359593 5851635 APJL_0332 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651367.1 358751 D 434271 CDS YP_001651368.1 165975775 5851658 359680..360321 1 NC_010278.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 360321 pyrE 5851658 pyrE Actinobacillus pleuropneumoniae serovar 3 str. JL03 orotate phosphoribosyltransferase YP_001651368.1 359680 D 434271 CDS YP_001651369.1 165975776 5850828 360460..361548 1 NC_010278.1 cobalamin-independent methionine synthase II 361548 5850828 APJL_0334 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cobalamin-independent methionine synthase II YP_001651369.1 360460 D 434271 CDS YP_001651370.1 165975777 5851624 complement(361625..362815) 1 NC_010278.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 362815 metC1 5851624 metC1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cystathionine beta-lyase YP_001651370.1 361625 R 434271 CDS YP_001651371.1 165975778 5851468 complement(362892..363431) 1 NC_010278.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 363431 dsbB 5851468 dsbB Actinobacillus pleuropneumoniae serovar 3 str. JL03 disulfide bond formation protein B YP_001651371.1 362892 R 434271 CDS YP_001651372.1 165975779 5851337 complement(363527..365068) 1 NC_010278.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 365068 nhaB 5851337 nhaB Actinobacillus pleuropneumoniae serovar 3 str. JL03 sodium/proton antiporter YP_001651372.1 363527 R 434271 CDS YP_001651373.1 165975780 5851393 365233..365961 1 NC_010278.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 365961 fadR 5851393 fadR Actinobacillus pleuropneumoniae serovar 3 str. JL03 fatty acid metabolism regulator YP_001651373.1 365233 D 434271 CDS YP_001651374.1 165975781 5850941 365970..367040 1 NC_010278.1 PhoH-like ATP-binding protein 367040 5850941 APJL_0339 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PhoH-like ATP-binding protein YP_001651374.1 365970 D 434271 CDS YP_001651375.1 165975782 5850880 complement(367079..368056) 1 NC_010278.1 hypothetical protein 368056 5850880 APJL_0340 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651375.1 367079 R 434271 CDS YP_001651376.1 165975783 5851614 complement(368127..369032) 1 NC_010278.1 peptide chain release factor 2 369032 prfB 5851614 prfB Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide chain release factor 2 YP_001651376.1 368127 R 434271 CDS YP_001651377.1 165975784 5851314 complement(369148..369225) 1 NC_010278.1 hypothetical protein 369225 5851314 APJL_0342 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651377.1 369148 R 434271 CDS YP_001651378.1 165975785 5851555 369438..370409 1 NC_010278.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 370409 selD 5851555 selD Actinobacillus pleuropneumoniae serovar 3 str. JL03 selenophosphate synthetase YP_001651378.1 369438 D 434271 CDS YP_001651379.1 165975786 5851175 370414..370869 1 NC_010278.1 putative Nudix hydrolase ymfB 370869 ymfB 5851175 ymfB Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative Nudix hydrolase ymfB YP_001651379.1 370414 D 434271 CDS YP_001651380.1 165975787 5851084 370879..372078 1 NC_010278.1 UbiH protein (2-octaprenyl-6-methoxyphenol) 372078 ubiH 5851084 ubiH Actinobacillus pleuropneumoniae serovar 3 str. JL03 UbiH protein (2-octaprenyl-6-methoxyphenol) YP_001651380.1 370879 D 434271 CDS YP_001651381.1 165975788 5850715 complement(372108..372584) 1 NC_010278.1 hypothetical protein 372584 5850715 APJL_0346 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651381.1 372108 R 434271 CDS YP_001651382.1 165975789 5851657 complement(372641..373396) 1 NC_010278.1 putative lipoprotein 373396 5851657 APJL_0347 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative lipoprotein YP_001651382.1 372641 R 434271 CDS YP_001651383.1 165975790 5851275 complement(373477..373956) 1 NC_010278.1 lipoprotein HlpB 373956 hlpB 5851275 hlpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein HlpB YP_001651383.1 373477 R 434271 CDS YP_001651384.1 165975791 5850858 complement(374092..375237) 1 NC_010278.1 monoxygenase 375237 visC 5850858 visC Actinobacillus pleuropneumoniae serovar 3 str. JL03 monoxygenase YP_001651384.1 374092 R 434271 CDS YP_001651385.1 165975792 5850793 complement(375362..376222) 1 NC_010278.1 hypothetical protein 376222 5850793 APJL_0350 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651385.1 375362 R 434271 CDS YP_001651386.1 165975793 5850849 complement(376241..376768) 1 NC_010278.1 PTS system, nitrogen regulatory IIA-like protein 376768 ptsN1 5850849 ptsN1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system, nitrogen regulatory IIA-like protein YP_001651386.1 376241 R 434271 CDS YP_001651387.1 165975794 5850940 complement(376803..377528) 1 NC_010278.1 ABC transporter ATP-binding protein 377528 5850940 APJL_0352 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001651387.1 376803 R 434271 CDS YP_001651388.1 165975795 5851451 complement(377538..378041) 1 NC_010278.1 hypothetical protein 378041 5851451 APJL_0353 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651388.1 377538 R 434271 CDS YP_001651389.1 165975796 5851392 complement(378066..378662) 1 NC_010278.1 hypothetical protein 378662 5851392 APJL_0354 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651389.1 378066 R 434271 CDS YP_001651390.1 165975797 5851547 complement(378822..381461) 1 NC_010278.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 381461 ppc 5851547 ppc Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoenolpyruvate carboxylase YP_001651390.1 378822 R 434271 CDS YP_001651391.1 165975798 5851045 complement(381676..382479) 1 NC_010278.1 beta-propeller domain-containing protein 382479 5851045 APJL_0356 Actinobacillus pleuropneumoniae serovar 3 str. JL03 beta-propeller domain-containing protein YP_001651391.1 381676 R 434271 CDS YP_001651392.1 165975799 5851326 complement(382476..382925) 1 NC_010278.1 hypothetical protein 382925 5851326 APJL_0357 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651392.1 382476 R 434271 CDS YP_001651393.1 165975800 5851952 complement(382992..383576) 1 NC_010278.1 LemA protein 383576 lemA 5851952 lemA Actinobacillus pleuropneumoniae serovar 3 str. JL03 LemA protein YP_001651393.1 382992 R 434271 CDS YP_001651394.1 165975801 5851333 complement(383730..385391) 1 NC_010278.1 phosphotransferase system, fructose-specific IIC component 385391 fruA 5851333 fruA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphotransferase system, fructose-specific IIC component YP_001651394.1 383730 R 434271 CDS YP_001651395.1 165975802 5851375 complement(385473..386420) 1 NC_010278.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 386420 fruK 5851375 fruK Actinobacillus pleuropneumoniae serovar 3 str. JL03 1-phosphofructokinase YP_001651395.1 385473 R 434271 CDS YP_001651396.1 165975803 5851294 complement(386435..387943) 1 NC_010278.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 387943 ptsN2 5851294 ptsN2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_001651396.1 386435 R 434271 CDS YP_001651397.1 165975804 5851662 388204..390537 1 NC_010278.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 390537 glgB 5851662 glgB Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycogen branching protein YP_001651397.1 388204 D 434271 CDS YP_001651398.1 165975805 5851366 390544..392529 1 NC_010278.1 glycogen operon protein 392529 glgX 5851366 glgX Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycogen operon protein YP_001651398.1 390544 D 434271 CDS YP_001651399.1 165975806 5851709 392545..393861 1 NC_010278.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 393861 glgC 5851709 glgC Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucose-1-phosphate adenylyltransferase YP_001651399.1 392545 D 434271 CDS YP_001651400.1 165975807 5851754 393991..395400 1 NC_010278.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 395400 glgA 5851754 glgA Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycogen synthase YP_001651400.1 393991 D 434271 CDS YP_001651401.1 165975808 5851777 395430..397934 1 NC_010278.1 glucan phosphorylase 397934 5851777 APJL_0366 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucan phosphorylase YP_001651401.1 395430 D 434271 CDS YP_001651402.1 165975809 5851870 complement(398046..398462) 1 NC_010278.1 nucleoside diphosphate kinase 398462 ndk 5851870 ndk Actinobacillus pleuropneumoniae serovar 3 str. JL03 nucleoside diphosphate kinase YP_001651402.1 398046 R 434271 CDS YP_001651403.1 165975810 5851781 complement(398521..400569) 1 NC_010278.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 400569 metG 5851781 metG Actinobacillus pleuropneumoniae serovar 3 str. JL03 methionyl-tRNA synthetase YP_001651403.1 398521 R 434271 CDS YP_001651404.1 165975811 5851939 400736..401698 1 NC_010278.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 401698 menC 5851939 menC Actinobacillus pleuropneumoniae serovar 3 str. JL03 O-succinylbenzoate synthase YP_001651404.1 400736 D 434271 CDS YP_001651405.1 165975812 5851765 complement(401734..401895) 1 NC_010278.1 hypothetical protein 401895 5851765 APJL_0370 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651405.1 401734 R 434271 CDS YP_001651406.1 165975813 5851908 402012..402704 1 NC_010278.1 ribosomal small subunit pseudouridine synthase A 402704 rsuA 5851908 rsuA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosomal small subunit pseudouridine synthase A YP_001651406.1 402012 D 434271 CDS YP_001651407.1 165975814 5851842 402704..403900 1 NC_010278.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 403900 proP 5851842 proP Actinobacillus pleuropneumoniae serovar 3 str. JL03 bicyclomycin/multidrug efflux system protein YP_001651407.1 402704 D 434271 CDS YP_001651408.1 165975815 5851820 complement(403946..404332) 1 NC_010278.1 hypothetical protein 404332 5851820 APJL_0373 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651408.1 403946 R 434271 CDS YP_001651409.1 165975816 5851883 complement(404403..404972) 1 NC_010278.1 component of anaerobic dehydrogenase 404972 5851883 APJL_0374 Actinobacillus pleuropneumoniae serovar 3 str. JL03 component of anaerobic dehydrogenase YP_001651409.1 404403 R 434271 CDS YP_001651410.1 165975817 5851881 405030..405872 1 NC_010278.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 405872 nfo 5851881 nfo Actinobacillus pleuropneumoniae serovar 3 str. JL03 endonuclease IV YP_001651410.1 405030 D 434271 CDS YP_001651411.1 165975818 5851532 405993..406589 1 NC_010278.1 lipoprotein NlpC 406589 nlpC 5851532 nlpC Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein NlpC YP_001651411.1 405993 D 434271 CDS YP_001651412.1 165975819 5850795 complement(406638..407093) 1 NC_010278.1 SOS-response transcriptional repressor 407093 5850795 APJL_0377 Actinobacillus pleuropneumoniae serovar 3 str. JL03 SOS-response transcriptional repressor YP_001651412.1 406638 R 434271 CDS YP_001651413.1 165975820 5851720 407116..407241 1 NC_010278.1 hypothetical protein 407241 5851720 APJL_0378 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651413.1 407116 D 434271 CDS YP_001651414.1 165975821 5851943 complement(407319..407705) 1 NC_010278.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 407705 5851943 APJL_0379 Actinobacillus pleuropneumoniae serovar 3 str. JL03 autonomous glycyl radical cofactor GrcA YP_001651414.1 407319 R 434271 CDS YP_001651415.1 165975822 5851900 407911..408588 1 NC_010278.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 408588 ung 5851900 ung Actinobacillus pleuropneumoniae serovar 3 str. JL03 uracil-DNA glycosylase YP_001651415.1 407911 D 434271 CDS YP_001651416.1 165975823 5851802 complement(408686..409558) 1 NC_010278.1 hypothetical protein 409558 5851802 APJL_0381 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651416.1 408686 R 434271 CDS YP_001651417.1 165975824 5851789 complement(409653..412451) 1 NC_010278.1 serotype-specific antigen 1 412451 5851789 APJL_0382 Actinobacillus pleuropneumoniae serovar 3 str. JL03 serotype-specific antigen 1 YP_001651417.1 409653 R 434271 CDS YP_001651418.1 165975825 5851831 complement(412603..416502) 1 NC_010278.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 416502 hrpA 5851831 hrpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent RNA helicase HrpA YP_001651418.1 412603 R 434271 CDS YP_001651419.1 165975826 5851917 complement(416638..417090) 1 NC_010278.1 hypothetical protein 417090 5851917 APJL_0384 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651419.1 416638 R 434271 CDS YP_001651420.1 165975827 5851604 complement(417287..417883) 1 NC_010278.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 417883 grpE 5851604 grpE Actinobacillus pleuropneumoniae serovar 3 str. JL03 heat shock protein GrpE YP_001651420.1 417287 R 434271 CDS YP_001651421.1 165975828 5851376 418128..419210 1 NC_010278.1 spermidine/putrescine-binding periplasmic protein 419210 potD2 5851376 potD2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 spermidine/putrescine-binding periplasmic protein YP_001651421.1 418128 D 434271 CDS YP_001651422.1 165975829 5852022 419354..420745 1 NC_010278.1 multidrug resistance protein 420745 norM 5852022 norM Actinobacillus pleuropneumoniae serovar 3 str. JL03 multidrug resistance protein YP_001651422.1 419354 D 434271 CDS YP_001651423.1 165975830 5851967 420761..424369 1 NC_010278.1 exodeoxyribonuclease V subunit beta 424369 recB 5851967 recB Actinobacillus pleuropneumoniae serovar 3 str. JL03 exodeoxyribonuclease V subunit beta YP_001651423.1 420761 D 434271 CDS YP_001651424.1 165975831 5851694 complement(424447..425958) 1 NC_010278.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 425958 lnt 5851694 lnt Actinobacillus pleuropneumoniae serovar 3 str. JL03 apolipoprotein N-acyltransferase YP_001651424.1 424447 R 434271 CDS YP_001651425.1 165975832 5851868 complement(426033..426926) 1 NC_010278.1 magnesium and cobalt efflux protein 426926 corC 5851868 corC Actinobacillus pleuropneumoniae serovar 3 str. JL03 magnesium and cobalt efflux protein YP_001651425.1 426033 R 434271 CDS YP_001651426.1 165975833 5851811 427096..427698 1 NC_010278.1 hypothetical protein 427698 5851811 APJL_0391 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651426.1 427096 D 434271 CDS YP_001651427.1 165975834 5852017 427934..428716 1 NC_010278.1 glycerol uptake facilitator protein 428716 glpF 5852017 glpF Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerol uptake facilitator protein YP_001651427.1 427934 D 434271 CDS YP_001651428.1 165975835 5851759 428751..430262 1 NC_010278.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 430262 glpK 5851759 glpK Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerol kinase YP_001651428.1 428751 D 434271 CDS YP_001651429.1 165975836 5852841 complement(430383..432791) 1 NC_010278.1 ATP-dependent protease LA 432791 lon 5852841 lon Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent protease LA YP_001651429.1 430383 R 434271 CDS YP_001651430.1 165975837 5850846 complement(432937..434253) 1 NC_010278.1 glycerol 3-phosphate transporter 434253 glpT 5850846 glpT Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerol 3-phosphate transporter YP_001651430.1 432937 R 434271 CDS YP_001651431.1 165975838 5851751 435924..437609 1 NC_010278.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 437609 glpA 5851751 glpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 sn-glycerol-3-phosphate dehydrogenase subunit A YP_001651431.1 435924 D 434271 CDS YP_001651432.1 165975839 5851892 437599..438885 1 NC_010278.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 438885 glpB 5851892 glpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_001651432.1 437599 D 434271 CDS YP_001651433.1 165975840 5851718 438882..440156 1 NC_010278.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 440156 glpC 5851718 glpC Actinobacillus pleuropneumoniae serovar 3 str. JL03 sn-glycerol-3-phosphate dehydrogenase subunit C YP_001651433.1 438882 D 434271 CDS YP_001651434.1 165975841 5851778 complement(440216..440407) 1 NC_010278.1 hypothetical protein 440407 5851778 APJL_0401 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651434.1 440216 R 434271 CDS YP_001651435.1 165975842 5851935 440466..441560 1 NC_010278.1 riboflavin-specific deaminase 441560 ribD 5851935 ribD Actinobacillus pleuropneumoniae serovar 3 str. JL03 riboflavin-specific deaminase YP_001651435.1 440466 D 434271 CDS YP_001651436.1 165975843 5851740 441685..442332 1 NC_010278.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 442332 ribE 5851740 ribE Actinobacillus pleuropneumoniae serovar 3 str. JL03 riboflavin synthase subunit alpha YP_001651436.1 441685 D 434271 CDS YP_001651437.1 165975844 5851822 442393..443598 1 NC_010278.1 riboflavin biosynthesis protein ribA 443598 ribA 5851822 ribA Actinobacillus pleuropneumoniae serovar 3 str. JL03 riboflavin biosynthesis protein ribA YP_001651437.1 442393 D 434271 CDS YP_001651438.1 165975845 5851914 443709..444170 1 NC_010278.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 444170 ribH 5851914 ribH Actinobacillus pleuropneumoniae serovar 3 str. JL03 6,7-dimethyl-8-ribityllumazine synthase YP_001651438.1 443709 D 434271 CDS YP_001651439.1 165975846 5851723 444440..445228 1 NC_010278.1 hypothetical protein 445228 5851723 APJL_0406 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651439.1 444440 D 434271 CDS YP_001651440.1 165975847 5851799 complement(445357..445845) 1 NC_010278.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 445845 greB 5851799 greB Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcription elongation factor GreB YP_001651440.1 445357 R 434271 CDS YP_001651441.1 165975848 5852845 complement(445855..446790) 1 NC_010278.1 phosphosugar isomerase 446790 5852845 APJL_0408 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphosugar isomerase YP_001651441.1 445855 R 434271 CDS YP_001651442.1 165975849 5851933 complement(446918..448210) 1 NC_010278.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 448210 pepB 5851933 pepB Actinobacillus pleuropneumoniae serovar 3 str. JL03 aminopeptidase B YP_001651442.1 446918 R 434271 CDS YP_001651443.1 165975850 5851796 complement(448325..449140) 1 NC_010278.1 lipoprotein E 449140 ompP4 5851796 ompP4 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein E YP_001651443.1 448325 R 434271 CDS YP_001651444.1 165975851 5851797 449313..450251 1 NC_010278.1 Na+-dependent transporter 450251 5851797 APJL_0411 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na+-dependent transporter YP_001651444.1 449313 D 434271 CDS YP_001651445.1 165975852 5851898 complement(450331..451512) 1 NC_010278.1 membrane-fusion protein 451512 acrA1 5851898 acrA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane-fusion protein YP_001651445.1 450331 R 434271 CDS YP_001651446.1 165975853 5851925 complement(451609..452424) 1 NC_010278.1 HAD superfamily hydrolase 452424 5851925 APJL_0413 Actinobacillus pleuropneumoniae serovar 3 str. JL03 HAD superfamily hydrolase YP_001651446.1 451609 R 434271 CDS YP_001651447.1 165975854 5852832 453021..454562 1 NC_010278.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 454562 leuA 5852832 leuA Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-isopropylmalate synthase YP_001651447.1 453021 D 434271 CDS YP_001651448.1 165975855 5850859 454905..455483 1 NC_010278.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 455483 rpoE 5850859 rpoE Actinobacillus pleuropneumoniae serovar 3 str. JL03 RNA polymerase sigma factor RpoE YP_001651448.1 454905 D 434271 CDS YP_001651449.1 165975856 5851767 455503..456126 1 NC_010278.1 sigma-E factor negative regulatory protein 456126 rseA 5851767 rseA Actinobacillus pleuropneumoniae serovar 3 str. JL03 sigma-E factor negative regulatory protein YP_001651449.1 455503 D 434271 CDS YP_001651450.1 165975857 5851227 456354..456779 1 NC_010278.1 sigma-E factor regulatory protein 456779 rseC 5851227 rseC Actinobacillus pleuropneumoniae serovar 3 str. JL03 sigma-E factor regulatory protein YP_001651450.1 456354 D 434271 CDS YP_001651451.1 165975858 5852846 456791..458482 1 NC_010278.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 458482 lcfA 5852846 lcfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 long-chain-fatty-acid--CoA ligase YP_001651451.1 456791 D 434271 CDS YP_001651452.1 165975859 5851680 458549..459175 1 NC_010278.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 459175 upp 5851680 upp Actinobacillus pleuropneumoniae serovar 3 str. JL03 uracil phosphoribosyltransferase YP_001651452.1 458549 D 434271 CDS YP_001651453.1 165975860 5851899 complement(459282..460151) 1 NC_010278.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 460151 ksgA 5851899 ksgA Actinobacillus pleuropneumoniae serovar 3 str. JL03 dimethyladenosine transferase YP_001651453.1 459282 R 434271 CDS YP_001651454.1 165975861 5852836 complement(460217..461167) 1 NC_010278.1 survival SurA-like protein 461167 surA 5852836 surA Actinobacillus pleuropneumoniae serovar 3 str. JL03 survival SurA-like protein YP_001651454.1 460217 R 434271 CDS YP_001651455.1 165975862 5851681 complement(461248..461787) 1 NC_010278.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 461787 pyrR 5851681 pyrR Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_001651455.1 461248 R 434271 CDS YP_001651456.1 165975863 5852051 complement(461803..463233) 1 NC_010278.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 463233 waaE 5852051 waaE Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_001651456.1 461803 R 434271 CDS YP_001651457.1 165975864 5852048 complement(463347..464867) 1 NC_010278.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 464867 engA 5852048 engA Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTP-binding protein EngA YP_001651457.1 463347 R 434271 CDS YP_001651458.1 165975865 5852041 complement(465025..466335) 1 NC_010278.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 466335 hemA 5852041 hemA Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutamyl-tRNA reductase YP_001651458.1 465025 R 434271 CDS YP_001651459.1 165975866 5852118 468896..470086 1 NC_010278.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 470086 dxr 5852118 dxr Actinobacillus pleuropneumoniae serovar 3 str. JL03 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001651459.1 468896 D 434271 CDS YP_001651460.1 165975867 5852802 complement(470171..470959) 1 NC_010278.1 hypothetical protein 470959 5852802 APJL_0429 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651460.1 470171 R 434271 CDS YP_001651461.1 165975868 5852125 complement(472065..472529) 1 NC_010278.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 472529 fabZ 5852125 fabZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 (3R)-hydroxymyristoyl-ACP dehydratase YP_001651461.1 472065 R 434271 CDS YP_001651462.1 165975869 5852519 complement(472598..473623) 1 NC_010278.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 473623 lpxD 5852519 lpxD Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001651462.1 472598 R 434271 CDS YP_001651463.1 165975870 5852560 complement(473623..474429) 1 NC_010278.1 outer membrane protein 474429 5852560 APJL_0434 Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein YP_001651463.1 473623 R 434271 CDS YP_001651464.1 165975871 5852202 complement(474545..476926) 1 NC_010278.1 outer membrane protein D-15 476926 ompD 5852202 ompD Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein D-15 YP_001651464.1 474545 R 434271 CDS YP_001651465.1 165975872 5851809 complement(476988..478301) 1 NC_010278.1 putative zinc metalloprotease 478301 ecfE 5851809 ecfE Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative zinc metalloprotease YP_001651465.1 476988 R 434271 CDS YP_001651466.1 165975873 5852814 complement(478308..479177) 1 NC_010278.1 phosphatidate cytidylyltransferase 479177 cdsA 5852814 cdsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphatidate cytidylyltransferase YP_001651466.1 478308 R 434271 CDS YP_001651467.1 165975874 5852809 complement(479202..479915) 1 NC_010278.1 undecaprenyl pyrophosphate synthetase 479915 uppS 5852809 uppS Actinobacillus pleuropneumoniae serovar 3 str. JL03 undecaprenyl pyrophosphate synthetase YP_001651467.1 479202 R 434271 CDS YP_001651468.1 165975875 5852824 complement(480088..480795) 1 NC_010278.1 hydroxyacylglutathione hydrolase 480795 gloB 5852824 gloB Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydroxyacylglutathione hydrolase YP_001651468.1 480088 R 434271 CDS YP_001651469.1 165975876 5852834 complement(480854..481771) 1 NC_010278.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 481771 5852834 APJL_0440 Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetyl-D-glucosamine kinase YP_001651469.1 480854 R 434271 CDS YP_001651470.1 165975877 5852833 complement(481774..482511) 1 NC_010278.1 phosphatidylglycerophosphatase B 482511 pgpB 5852833 pgpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphatidylglycerophosphatase B YP_001651470.1 481774 R 434271 CDS YP_001651471.1 165975878 5852825 complement(482570..482887) 1 NC_010278.1 putative RNA-binding protein 482887 5852825 APJL_0442 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative RNA-binding protein YP_001651471.1 482570 R 434271 CDS YP_001651472.1 165975879 5852842 483009..483767 1 NC_010278.1 putative glycosyltransferase 483767 5852842 APJL_0443 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative glycosyltransferase YP_001651472.1 483009 D 434271 CDS YP_001651473.1 165975880 5852829 complement(484735..485772) 1 NC_010278.1 heptosyltransferase 485772 waaQ 5852829 waaQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 heptosyltransferase YP_001651473.1 484735 R 434271 CDS YP_001651474.1 165975881 5851696 486016..487347 1 NC_010278.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 487347 argG 5851696 argG Actinobacillus pleuropneumoniae serovar 3 str. JL03 argininosuccinate synthase YP_001651474.1 486016 D 434271 CDS YP_001651475.1 165975882 5851414 487469..487930 1 NC_010278.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 487930 rnhA 5851414 rnhA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease H YP_001651475.1 487469 D 434271 CDS YP_001651476.1 165975883 5852425 488087..488590 1 NC_010278.1 colicin V production protein 488590 cvpA 5852425 cvpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 colicin V production protein YP_001651476.1 488087 D 434271 CDS YP_001651477.1 165975884 5852782 488604..490121 1 NC_010278.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 490121 purF 5852782 purF Actinobacillus pleuropneumoniae serovar 3 str. JL03 amidophosphoribosyltransferase YP_001651477.1 488604 D 434271 CDS YP_001651478.1 165975885 5851700 complement(490190..490645) 1 NC_010278.1 hypothetical protein 490645 5851700 APJL_0451 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651478.1 490190 R 434271 CDS YP_001651479.1 165975886 5851647 complement(490744..492084) 1 NC_010278.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 492084 gdhA 5851647 gdhA Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutamate dehydrogenase YP_001651479.1 490744 R 434271 CDS YP_001651480.1 165975887 5851949 complement(492388..492732) 1 NC_010278.1 small protein A 492732 smpA 5851949 smpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 small protein A YP_001651480.1 492388 R 434271 CDS YP_001651481.1 165975888 5851373 complement(492803..493804) 1 NC_010278.1 nucleoid-associated protein NdpA 493804 ndpA 5851373 ndpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 nucleoid-associated protein NdpA YP_001651481.1 492803 R 434271 CDS YP_001651482.1 165975889 5851757 493897..494286 1 NC_010278.1 putative translation initiation inhibitor 494286 5851757 APJL_0455 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative translation initiation inhibitor YP_001651482.1 493897 D 434271 CDS YP_001651483.1 165975890 5851808 494314..495051 1 NC_010278.1 hypothetical protein 495051 5851808 APJL_0456 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651483.1 494314 D 434271 CDS YP_001651484.1 165975891 5851253 complement(495271..495471) 1 NC_010278.1 hypothetical protein 495471 5851253 APJL_0457 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651484.1 495271 R 434271 CDS YP_001651485.1 165975892 5851950 495616..496698 1 NC_010278.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 496698 leuB 5851950 leuB Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-isopropylmalate dehydrogenase YP_001651485.1 495616 D 434271 CDS YP_001651486.1 165975893 5851510 complement(496822..497217) 1 NC_010278.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 497217 msrB 5851510 msrB Actinobacillus pleuropneumoniae serovar 3 str. JL03 methionine sulfoxide reductase B YP_001651486.1 496822 R 434271 CDS YP_001651487.1 165975894 5851715 497440..498444 1 NC_010278.1 glyceraldehyde 3-phosphate dehydrogenase 498444 gapA 5851715 gapA Actinobacillus pleuropneumoniae serovar 3 str. JL03 glyceraldehyde 3-phosphate dehydrogenase YP_001651487.1 497440 D 434271 CDS YP_001651488.1 165975895 5851489 498640..499692 1 NC_010278.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 499692 mreB 5851489 mreB Actinobacillus pleuropneumoniae serovar 3 str. JL03 rod shape-determining protein MreB YP_001651488.1 498640 D 434271 CDS YP_001651489.1 165975896 5851600 499809..500858 1 NC_010278.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 500858 mreC 5851600 mreC Actinobacillus pleuropneumoniae serovar 3 str. JL03 rod shape-determining protein MreC YP_001651489.1 499809 D 434271 CDS YP_001651490.1 165975897 5851745 500858..501346 1 NC_010278.1 rod shape-determining protein 501346 mreD 5851745 mreD Actinobacillus pleuropneumoniae serovar 3 str. JL03 rod shape-determining protein YP_001651490.1 500858 D 434271 CDS YP_001651491.1 165975898 5851955 501413..502699 1 NC_010278.1 recombination factor protein RarA 502699 5851955 APJL_0464 Actinobacillus pleuropneumoniae serovar 3 str. JL03 recombination factor protein RarA YP_001651491.1 501413 D 434271 CDS YP_001651492.1 165975899 5851756 502780..503565 1 NC_010278.1 high-affinity zinc uptake system membrane protein 503565 znuB 5851756 znuB Actinobacillus pleuropneumoniae serovar 3 str. JL03 high-affinity zinc uptake system membrane protein YP_001651492.1 502780 D 434271 CDS YP_001651493.1 165975900 5851176 503745..504542 1 NC_010278.1 putative glutamine amidotransferase 504542 5851176 APJL_0466 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative glutamine amidotransferase YP_001651493.1 503745 D 434271 CDS YP_001651494.1 165975901 5850993 complement(504622..505698) 1 NC_010278.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 505698 metX 5850993 metX Actinobacillus pleuropneumoniae serovar 3 str. JL03 homoserine O-acetyltransferase YP_001651494.1 504622 R 434271 CDS YP_001651495.1 165975902 5851037 505990..506679 1 NC_010278.1 SanA protein 506679 sanA 5851037 sanA Actinobacillus pleuropneumoniae serovar 3 str. JL03 SanA protein YP_001651495.1 505990 D 434271 CDS YP_001651496.1 165975903 5851645 complement(517296..517994) 1 NC_010278.1 hypothetical protein 517994 5851645 APJL_0471 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651496.1 517296 R 434271 CDS YP_001651497.1 165975904 5850842 complement(518123..519532) 1 NC_010278.1 iron-sulfur electron transport protein 519532 ykgF 5850842 ykgF Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-sulfur electron transport protein YP_001651497.1 518123 R 434271 CDS YP_001651498.1 165975905 5851866 complement(519542..520267) 1 NC_010278.1 dehydrogenase 520267 ykgE 5851866 ykgE Actinobacillus pleuropneumoniae serovar 3 str. JL03 dehydrogenase YP_001651498.1 519542 R 434271 CDS YP_001651499.1 165975906 5851691 complement(520437..522032) 1 NC_010278.1 L-lactate permease 522032 lctP 5851691 lctP Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-lactate permease YP_001651499.1 520437 R 434271 CDS YP_001651500.1 165975907 5851245 complement(522501..522908) 1 NC_010278.1 DNA-binding protein H-NS 522908 hns 5851245 hns Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding protein H-NS YP_001651500.1 522501 R 434271 CDS YP_001651501.1 165975908 5851659 523465..524982 1 NC_010278.1 Na+/H+ antiporter 524982 5851659 APJL_0476 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na+/H+ antiporter YP_001651501.1 523465 D 434271 CDS YP_001651502.1 165975909 5851854 525188..526159 1 NC_010278.1 D-galactose transport system substrate-binding protein 526159 mglB 5851854 mglB Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-galactose transport system substrate-binding protein YP_001651502.1 525188 D 434271 CDS YP_001651503.1 165975910 5851052 complement(526294..527166) 1 NC_010278.1 succinyl-CoA synthetase alpha chain 527166 sucD 5851052 sucD Actinobacillus pleuropneumoniae serovar 3 str. JL03 succinyl-CoA synthetase alpha chain YP_001651503.1 526294 R 434271 CDS YP_001651504.1 165975911 5851617 complement(527169..528335) 1 NC_010278.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 528335 sucC 5851617 sucC Actinobacillus pleuropneumoniae serovar 3 str. JL03 succinyl-CoA synthetase subunit beta YP_001651504.1 527169 R 434271 CDS YP_001651505.1 165975912 5851019 complement(528479..529345) 1 NC_010278.1 hypothetical protein 529345 lapB 5851019 lapB Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651505.1 528479 R 434271 CDS YP_001651506.1 165975913 5850910 complement(529488..530717) 1 NC_010278.1 dihydrolipoamide succinyltransferase 530717 sucB 5850910 sucB Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydrolipoamide succinyltransferase YP_001651506.1 529488 R 434271 CDS YP_001651507.1 165975914 5850948 complement(530837..533647) 1 NC_010278.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 533647 sucA 5850948 sucA Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-oxoglutarate dehydrogenase E1 component YP_001651507.1 530837 R 434271 CDS YP_001651508.1 165975915 5851488 complement(533890..534690) 1 NC_010278.1 zinc ABC transporter ATP-binding protein 534690 znuC 5851488 znuC Actinobacillus pleuropneumoniae serovar 3 str. JL03 zinc ABC transporter ATP-binding protein YP_001651508.1 533890 R 434271 CDS YP_001651509.1 165975916 5851628 534894..536384 1 NC_010278.1 putative metalloprotease 536384 5851628 APJL_0484 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative metalloprotease YP_001651509.1 534894 D 434271 CDS YP_001651510.1 165975917 5851206 536403..537098 1 NC_010278.1 thiol:disulfide interchange protein 537098 dsbC 5851206 dsbC Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol:disulfide interchange protein YP_001651510.1 536403 D 434271 CDS YP_001651511.1 165975918 5851607 537367..538905 1 NC_010278.1 single-stranded-DNA-specific exonuclease 538905 recJ 5851607 recJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 single-stranded-DNA-specific exonuclease YP_001651511.1 537367 D 434271 CDS YP_001651512.1 165975919 5850934 539039..539890 1 NC_010278.1 lipoprotein 539890 plpD 5850934 plpD Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein YP_001651512.1 539039 D 434271 CDS YP_001651513.1 165975920 5851477 539972..540790 1 NC_010278.1 phosphatase 540790 5851477 APJL_0488 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphatase YP_001651513.1 539972 D 434271 CDS YP_001651514.1 165975921 5850810 540790..542505 1 NC_010278.1 nitrate/nitrite sensor protein NarQ 542505 narQ 5850810 narQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitrate/nitrite sensor protein NarQ YP_001651514.1 540790 D 434271 CDS YP_001651515.1 165975922 5851160 542528..543046 1 NC_010278.1 sortase and related acyltransferase 543046 5851160 APJL_0490 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sortase and related acyltransferase YP_001651515.1 542528 D 434271 CDS YP_001651516.1 165975923 5850822 543087..543683 1 NC_010278.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 543683 5850822 APJL_0491 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative deoxyribonucleotide triphosphate pyrophosphatase YP_001651516.1 543087 D 434271 CDS YP_001651517.1 165975924 5851707 543711..544031 1 NC_010278.1 hypothetical protein 544031 5851707 APJL_0492 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651517.1 543711 D 434271 CDS YP_001651518.1 165975925 5851109 complement(544137..545771) 1 NC_010278.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 545771 fhs 5851109 fhs Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate--tetrahydrofolate ligase YP_001651518.1 544137 R 434271 CDS YP_001651519.1 165975926 5851141 545917..546363 1 NC_010278.1 hypothetical protein 546363 5851141 APJL_0494 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651519.1 545917 D 434271 CDS YP_001651520.1 165975927 5851537 546453..547202 1 NC_010278.1 NADP-dependent dehydrogenase 547202 5851537 APJL_0495 Actinobacillus pleuropneumoniae serovar 3 str. JL03 NADP-dependent dehydrogenase YP_001651520.1 546453 D 434271 CDS YP_001651521.1 165975928 5851615 547388..548578 1 NC_010278.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 548578 trpB 5851615 trpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 tryptophan synthase subunit beta YP_001651521.1 547388 D 434271 CDS YP_001651522.1 165975929 5851038 548580..549389 1 NC_010278.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 549389 trpA 5851038 trpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 tryptophan synthase subunit alpha YP_001651522.1 548580 D 434271 CDS YP_001651523.1 165975930 5850878 complement(549466..549759) 1 NC_010278.1 hypothetical protein 549759 5850878 APJL_0498 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651523.1 549466 R 434271 CDS YP_001651524.1 165975931 5851798 complement(549768..550052) 1 NC_010278.1 hypothetical protein 550052 5851798 APJL_0499 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651524.1 549768 R 434271 CDS YP_001651525.1 165975932 5851884 550347..553106 1 NC_010278.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 553106 polA 5851884 polA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase I YP_001651525.1 550347 D 434271 CDS YP_001651526.1 165975933 5851980 553161..553358 1 NC_010278.1 hypothetical protein 553358 5851980 APJL_0501 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651526.1 553161 D 434271 CDS YP_001651527.1 165975934 5851915 553348..553641 1 NC_010278.1 plasmid stabilization system protein 553641 5851915 APJL_0502 Actinobacillus pleuropneumoniae serovar 3 str. JL03 plasmid stabilization system protein YP_001651527.1 553348 D 434271 CDS YP_001651528.1 165975935 5851747 553781..554422 1 NC_010278.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 554422 lolA 5851747 lolA Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer-membrane lipoprotein carrier protein YP_001651528.1 553781 D 434271 CDS YP_001651529.1 165975936 5851965 554497..554805 1 NC_010278.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 554805 5851965 APJL_0504 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Trp operon repressor YP_001651529.1 554497 D 434271 CDS YP_001651530.1 165975937 5852020 554834..555595 1 NC_010278.1 monofunctional biosynthetic peptidoglycan transglycosylase 555595 5852020 APJL_0505 Actinobacillus pleuropneumoniae serovar 3 str. JL03 monofunctional biosynthetic peptidoglycan transglycosylase YP_001651530.1 554834 D 434271 CDS YP_001651531.1 165975938 5851466 complement(555665..556000) 1 NC_010278.1 putative gamma-carboxymuconolactone decarboxylase subunit 556000 5851466 APJL_0506 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative gamma-carboxymuconolactone decarboxylase subunit YP_001651531.1 555665 R 434271 CDS YP_001651532.1 165975939 5850989 complement(556027..557031) 1 NC_010278.1 putative inner membrane transport protein 557031 5850989 APJL_0507 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative inner membrane transport protein YP_001651532.1 556027 R 434271 CDS YP_001651533.1 165975940 5851416 complement(557046..557387) 1 NC_010278.1 hypothetical protein 557387 5851416 APJL_0508 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651533.1 557046 R 434271 CDS YP_001651534.1 165975941 5851513 complement(557398..558741) 1 NC_010278.1 sulfide:quinone oxidoreductase 558741 5851513 APJL_0509 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfide:quinone oxidoreductase YP_001651534.1 557398 R 434271 CDS YP_001651535.1 165975942 5850816 complement(558786..558998) 1 NC_010278.1 hypothetical protein 558998 5850816 APJL_0510 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651535.1 558786 R 434271 CDS YP_001651536.1 165975943 5851053 559153..559440 1 NC_010278.1 transcriptional regulator 559440 5851053 APJL_0511 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001651536.1 559153 D 434271 CDS YP_001651537.1 165975944 5851367 559515..560225 1 NC_010278.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 560225 5851367 APJL_0512 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitroreductase A YP_001651537.1 559515 D 434271 CDS YP_001651538.1 165975945 5850899 560222..561136 1 NC_010278.1 ribosomal protein S6 modification protein 561136 rimK 5850899 rimK Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosomal protein S6 modification protein YP_001651538.1 560222 D 434271 CDS YP_001651539.1 165975946 5850876 complement(561171..561929) 1 NC_010278.1 hypothetical protein 561929 5850876 APJL_0514 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651539.1 561171 R 434271 CDS YP_001651540.1 165975947 5851888 563699..563986 1 NC_010278.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 563986 rplY 5851888 rplY Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L25 YP_001651540.1 563699 D 434271 CDS YP_001651541.1 165975948 5851721 564565..565206 1 NC_010278.1 ABC transporter substrate-binding protein 565206 5851721 APJL_0518 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter substrate-binding protein YP_001651541.1 564565 D 434271 CDS YP_001651542.1 165975949 5851377 565329..566192 1 NC_010278.1 putative nickel/cobalt efflux system 566192 5851377 APJL_0519 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative nickel/cobalt efflux system YP_001651542.1 565329 D 434271 CDS YP_001651543.1 165975950 5851021 566292..567740 1 NC_010278.1 putative sodium/alanine symporter 567740 5851021 APJL_0520 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sodium/alanine symporter YP_001651543.1 566292 D 434271 CDS YP_001651544.1 165975951 5851230 568131..568223 1 NC_010278.1 hypothetical protein 568223 5851230 APJL_0521 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651544.1 568131 D 434271 CDS YP_001651545.1 165975952 5850973 568337..568861 1 NC_010278.1 ABC transporter ATP-binding protein 568861 nasD 5850973 nasD Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001651545.1 568337 D 434271 CDS YP_001651546.1 165975953 5851448 568933..569154 1 NC_010278.1 putative thiamine biosynthesis protein 569154 thiF 5851448 thiF Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative thiamine biosynthesis protein YP_001651546.1 568933 D 434271 CDS YP_001651547.1 165975954 5850862 569230..569430 1 NC_010278.1 thiamine biosynthesis protein 569430 thiS 5850862 thiS Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamine biosynthesis protein YP_001651547.1 569230 D 434271 CDS YP_001651548.1 165975955 5850885 569511..569732 1 NC_010278.1 putative thiamine biosynthesis protein 569732 thiG1 5850885 thiG1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative thiamine biosynthesis protein YP_001651548.1 569511 D 434271 CDS YP_001651549.1 165975956 5851508 569866..570276 1 NC_010278.1 putative thiamine biosynthesis protein 570276 thiG2 5851508 thiG2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative thiamine biosynthesis protein YP_001651549.1 569866 D 434271 CDS YP_001651550.1 165975957 5851039 570286..571431 1 NC_010278.1 thiamine biosynthesis protein 571431 thiH 5851039 thiH Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamine biosynthesis protein YP_001651550.1 570286 D 434271 CDS YP_001651551.1 165975958 5850767 571458..572108 1 NC_010278.1 putative transcription activator 572108 5850767 APJL_0528 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transcription activator YP_001651551.1 571458 D 434271 CDS YP_001651552.1 165975959 5851036 572131..572931 1 NC_010278.1 sulfonate/nitrate/taurine transport system substrate-binding protein 572931 5851036 APJL_0529 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfonate/nitrate/taurine transport system substrate-binding protein YP_001651552.1 572131 D 434271 CDS YP_001651553.1 165975960 5851042 574299..576098 1 NC_010278.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 576098 lepA 5851042 lepA Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTP-binding protein LepA YP_001651553.1 574299 D 434271 CDS YP_001651554.1 165975961 5851087 576203..577162 1 NC_010278.1 signal peptidase I 577162 lepB 5851087 lepB Actinobacillus pleuropneumoniae serovar 3 str. JL03 signal peptidase I YP_001651554.1 576203 D 434271 CDS YP_001651555.1 165975962 5851559 577258..577929 1 NC_010278.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 577929 rnc 5851559 rnc Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease III YP_001651555.1 577258 D 434271 CDS YP_001651556.1 165975963 5851688 577999..578913 1 NC_010278.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 578913 era 5851688 era Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTP-binding protein Era YP_001651556.1 577999 D 434271 CDS YP_001651557.1 165975964 5851352 578924..579646 1 NC_010278.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 579646 recO 5851352 recO Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA repair protein RecO YP_001651557.1 578924 D 434271 CDS YP_001651558.1 165975965 5850791 complement(579740..581329) 1 NC_010278.1 Flp pilus assembly protein 581329 tadG 5850791 tadG Actinobacillus pleuropneumoniae serovar 3 str. JL03 Flp pilus assembly protein YP_001651558.1 579740 R 434271 CDS YP_001651559.1 165975966 5851271 complement(581353..582117) 1 NC_010278.1 tight adherence protein F 582117 tadF 5851271 tadF Actinobacillus pleuropneumoniae serovar 3 str. JL03 tight adherence protein F YP_001651559.1 581353 R 434271 CDS YP_001651560.1 165975967 5851517 complement(581921..582406) 1 NC_010278.1 tight adherence protein E 582406 tadE 5851517 tadE Actinobacillus pleuropneumoniae serovar 3 str. JL03 tight adherence protein E YP_001651560.1 581921 R 434271 CDS YP_001651561.1 165975968 5851384 complement(582409..583161) 1 NC_010278.1 Flp pilus assembly protein 583161 tadD 5851384 tadD Actinobacillus pleuropneumoniae serovar 3 str. JL03 Flp pilus assembly protein YP_001651561.1 582409 R 434271 CDS YP_001651562.1 165975969 5851516 complement(583151..583996) 1 NC_010278.1 Flp pilus assembly protein 583996 tadC 5851516 tadC Actinobacillus pleuropneumoniae serovar 3 str. JL03 Flp pilus assembly protein YP_001651562.1 583151 R 434271 CDS YP_001651563.1 165975970 5851687 complement(583996..584883) 1 NC_010278.1 Flp pilus assembly protein 584883 tadB 5851687 tadB Actinobacillus pleuropneumoniae serovar 3 str. JL03 Flp pilus assembly protein YP_001651563.1 583996 R 434271 CDS YP_001651564.1 165975971 5851071 complement(584883..586160) 1 NC_010278.1 tight adherence protein A 586160 tadA 5851071 tadA Actinobacillus pleuropneumoniae serovar 3 str. JL03 tight adherence protein A YP_001651564.1 584883 R 434271 CDS YP_001651565.1 165975972 5851415 complement(586169..587296) 1 NC_010278.1 Flp pilus assembly protein, ATPase 587296 tadZ 5851415 tadZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 Flp pilus assembly protein, ATPase YP_001651565.1 586169 R 434271 CDS YP_001651566.1 165975973 5850818 complement(587459..587962) 1 NC_010278.1 rough colony protein B 587962 rcpB 5850818 rcpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 rough colony protein B YP_001651566.1 587459 R 434271 CDS YP_001651567.1 165975974 5850999 complement(587959..589347) 1 NC_010278.1 Flp pilus assembly protein, secretin 589347 rcpA 5850999 rcpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 Flp pilus assembly protein, secretin YP_001651567.1 587959 R 434271 CDS YP_001651568.1 165975975 5850933 complement(589337..589561) 1 NC_010278.1 hypothetical protein 589561 5850933 APJL_0549 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651568.1 589337 R 434271 CDS YP_001651569.1 165975976 5851303 589522..589779 1 NC_010278.1 hypothetical protein 589779 5851303 APJL_0550 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651569.1 589522 D 434271 CDS YP_001651570.1 165975977 5851371 589830..591329 1 NC_010278.1 ATPase 591329 5851371 APJL_0551 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATPase YP_001651570.1 589830 D 434271 CDS YP_001651571.1 165975978 5850841 591526..592557 1 NC_010278.1 iron(III) transport system substrate-binding protein 592557 afuA2 5850841 afuA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron(III) transport system substrate-binding protein YP_001651571.1 591526 D 434271 CDS YP_001651572.1 165975979 5851436 592688..594688 1 NC_010278.1 iron(III) transport system permease 594688 afuB2 5851436 afuB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron(III) transport system permease YP_001651572.1 592688 D 434271 CDS YP_001651573.1 165975980 5851800 599064..599780 1 NC_010278.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 599780 rpsB 5851800 rpsB Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S2 YP_001651573.1 599064 D 434271 CDS YP_001651574.1 165975981 5851872 599876..600727 1 NC_010278.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 600727 tsf 5851872 tsf Actinobacillus pleuropneumoniae serovar 3 str. JL03 elongation factor Ts YP_001651574.1 599876 D 434271 CDS YP_001651575.1 165975982 5851910 complement(600856..602409) 1 NC_010278.1 membrane protein 602409 5851910 APJL_0561 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane protein YP_001651575.1 600856 R 434271 CDS YP_001651576.1 165975983 5851922 602521..603234 1 NC_010278.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 603234 pyrH 5851922 pyrH Actinobacillus pleuropneumoniae serovar 3 str. JL03 uridylate kinase YP_001651576.1 602521 D 434271 CDS YP_001651577.1 165975984 5851928 603418..603975 1 NC_010278.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 603975 frr 5851928 frr Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosome recycling factor YP_001651577.1 603418 D 434271 CDS YP_001651578.1 165975985 5851758 complement(604053..605453) 1 NC_010278.1 transcriptional regulator 605453 5851758 APJL_0564 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001651578.1 604053 R 434271 CDS YP_001651579.1 165975986 5851916 605540..606427 1 NC_010278.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 606427 5851916 APJL_0565 Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyridoxal biosynthesis lyase PdxS YP_001651579.1 605540 D 434271 CDS YP_001651580.1 165975987 5851843 606427..607002 1 NC_010278.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 607002 5851843 APJL_0566 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutamine amidotransferase subunit PdxT YP_001651580.1 606427 D 434271 CDS YP_001651581.1 165975988 5851907 complement(607076..607666) 1 NC_010278.1 tRNA-specific adenosine deaminase 607666 5851907 APJL_0567 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA-specific adenosine deaminase YP_001651581.1 607076 R 434271 CDS YP_001651582.1 165975989 5851790 complement(607683..609542) 1 NC_010278.1 cold-shock DEAD box protein-A 609542 deaD 5851790 deaD Actinobacillus pleuropneumoniae serovar 3 str. JL03 cold-shock DEAD box protein-A YP_001651582.1 607683 R 434271 CDS YP_001651583.1 165975990 5851920 complement(609764..610705) 1 NC_010278.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 610705 nlpI 5851920 nlpI Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein NlpI YP_001651583.1 609764 R 434271 CDS YP_001651584.1 165975991 5851945 complement(610766..612913) 1 NC_010278.1 polynucleotide phosphorylase/polyadenylase 612913 pnp 5851945 pnp Actinobacillus pleuropneumoniae serovar 3 str. JL03 polynucleotide phosphorylase/polyadenylase YP_001651584.1 610766 R 434271 CDS YP_001651585.1 165975992 5851909 613251..615461 1 NC_010278.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 615461 parC 5851909 parC Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA topoisomerase IV subunit A YP_001651585.1 613251 D 434271 CDS YP_001651586.1 165975993 5851947 615601..616932 1 NC_010278.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 616932 mukF 5851947 mukF Actinobacillus pleuropneumoniae serovar 3 str. JL03 condesin subunit F YP_001651586.1 615601 D 434271 CDS YP_001651587.1 165975994 5851894 617012..617725 1 NC_010278.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 617725 mukE 5851894 mukE Actinobacillus pleuropneumoniae serovar 3 str. JL03 condesin subunit E YP_001651587.1 617012 D 434271 CDS YP_001651588.1 165975995 5851760 617746..622236 1 NC_010278.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 622236 mukB 5851760 mukB Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein MukB YP_001651588.1 617746 D 434271 CDS YP_001651589.1 165975996 5851983 622313..623488 1 NC_010278.1 sugar efflux transporter 623488 5851983 APJL_0575 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sugar efflux transporter YP_001651589.1 622313 D 434271 CDS YP_001651590.1 165975997 5851673 complement(623540..625279) 1 NC_010278.1 putative sulfatase 625279 5851673 APJL_0576 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sulfatase YP_001651590.1 623540 R 434271 CDS YP_001651591.1 165975998 5852016 complement(625282..625503) 1 NC_010278.1 hypothetical protein 625503 5852016 APJL_0577 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651591.1 625282 R 434271 CDS YP_001651592.1 165975999 5851839 625713..626291 1 NC_010278.1 putative HTH-type transcriptional regulator 626291 5851839 APJL_0578 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative HTH-type transcriptional regulator YP_001651592.1 625713 D 434271 CDS YP_001651593.1 165976000 5851937 626324..627529 1 NC_010278.1 membrane-fusion protein 627529 5851937 APJL_0579 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane-fusion protein YP_001651593.1 626324 D 434271 CDS YP_001651594.1 165976001 5851846 627542..630661 1 NC_010278.1 acriflavine resistance protein 630661 5851846 APJL_0580 Actinobacillus pleuropneumoniae serovar 3 str. JL03 acriflavine resistance protein YP_001651594.1 627542 D 434271 CDS YP_001651595.1 165976002 5851833 630879..632243 1 NC_010278.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 632243 glmU 5851833 glmU Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001651595.1 630879 D 434271 CDS YP_001651596.1 165976003 5851896 complement(632350..632667) 1 NC_010278.1 hypothetical protein 632667 5851896 APJL_0582 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651596.1 632350 R 434271 CDS YP_001651597.1 165976004 5851837 complement(632671..633291) 1 NC_010278.1 exopolysaccharide biosynthesis protein 633291 5851837 APJL_0583 Actinobacillus pleuropneumoniae serovar 3 str. JL03 exopolysaccharide biosynthesis protein YP_001651597.1 632671 R 434271 CDS YP_001651598.1 165976005 5851753 633585..635243 1 NC_010278.1 phosphomannomutase 635243 yhxB 5851753 yhxB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphomannomutase YP_001651598.1 633585 D 434271 CDS YP_001651599.1 165976006 5851973 complement(635325..636896) 1 NC_010278.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 636896 guaA 5851973 guaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 GMP synthase YP_001651599.1 635325 R 434271 CDS YP_001651600.1 165976007 5851844 complement(636911..637225) 1 NC_010278.1 hypothetical protein 637225 5851844 APJL_0586 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651600.1 636911 R 434271 CDS YP_001651601.1 165976008 5852008 complement(637315..638778) 1 NC_010278.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 638778 guaB 5852008 guaB Actinobacillus pleuropneumoniae serovar 3 str. JL03 inosine 5'-monophosphate dehydrogenase YP_001651601.1 637315 R 434271 CDS YP_001651602.1 165976009 5851946 639031..639657 1 NC_010278.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 639657 rrmJ 5851946 rrmJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 23S rRNA methyltransferase J YP_001651602.1 639031 D 434271 CDS YP_001651603.1 165976010 5851961 639761..641683 1 NC_010278.1 cell division protein 641683 ftsH 5851961 ftsH Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001651603.1 639761 D 434271 CDS YP_001651604.1 165976011 5851815 641990..643135 1 NC_010278.1 tyrosine-specific transport protein 643135 tyrP1 5851815 tyrP1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tyrosine-specific transport protein YP_001651604.1 641990 D 434271 CDS YP_001651605.1 165976012 5851987 643300..644448 1 NC_010278.1 tyrosine-specific transport protein 644448 tyrP2 5851987 tyrP2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tyrosine-specific transport protein YP_001651605.1 643300 D 434271 CDS YP_001651606.1 165976013 5851743 644555..647107 1 NC_010278.1 PII uridylyl-transferase 647107 glnD 5851743 glnD Actinobacillus pleuropneumoniae serovar 3 str. JL03 PII uridylyl-transferase YP_001651606.1 644555 D 434271 CDS YP_001651607.1 165976014 5851885 complement(647140..647538) 1 NC_010278.1 hypothetical protein 647538 5851885 APJL_0593 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651607.1 647140 R 434271 CDS YP_001651608.1 165976015 5851990 647844..648272 1 NC_010278.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 648272 rplM 5851990 rplM Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L13 YP_001651608.1 647844 D 434271 CDS YP_001651609.1 165976016 5852006 648289..648684 1 NC_010278.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 648684 rpsI 5852006 rpsI Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S9 YP_001651609.1 648289 D 434271 CDS YP_001651610.1 165976017 5852830 648806..649588 1 NC_010278.1 hypothetical protein 649588 5852830 APJL_0596 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651610.1 648806 D 434271 CDS YP_001651611.1 165976018 5851991 649588..650133 1 NC_010278.1 hypothetical protein 650133 5851991 APJL_0597 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651611.1 649588 D 434271 CDS YP_001651612.1 165976019 5851717 650159..651082 1 NC_010278.1 cation-efflux pump FieF 651082 fieF 5851717 fieF Actinobacillus pleuropneumoniae serovar 3 str. JL03 cation-efflux pump FieF YP_001651612.1 650159 D 434271 CDS YP_001651613.1 165976020 5851652 651063..651833 1 NC_010278.1 hypothetical protein 651833 5851652 APJL_0599 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651613.1 651063 D 434271 CDS YP_001651614.1 165976021 5851819 651932..653257 1 NC_010278.1 proton glutamate symport protein 653257 5851819 APJL_0600 Actinobacillus pleuropneumoniae serovar 3 str. JL03 proton glutamate symport protein YP_001651614.1 651932 D 434271 CDS YP_001651615.1 165976022 5851932 complement(653359..654021) 1 NC_010278.1 putative NAD(P)H nitroreductase 654021 5851932 APJL_0601 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative NAD(P)H nitroreductase YP_001651615.1 653359 R 434271 CDS YP_001651616.1 165976023 5851847 654303..655289 1 NC_010278.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 655289 pheS 5851847 pheS Actinobacillus pleuropneumoniae serovar 3 str. JL03 phenylalanyl-tRNA synthetase subunit alpha YP_001651616.1 654303 D 434271 CDS YP_001651617.1 165976024 5852012 655387..657774 1 NC_010278.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 657774 pheT 5852012 pheT Actinobacillus pleuropneumoniae serovar 3 str. JL03 phenylalanyl-tRNA synthetase subunit beta YP_001651617.1 655387 D 434271 CDS YP_001651618.1 165976025 5851832 657792..658088 1 NC_010278.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 658088 ihfA 5851832 ihfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 integration host factor subunit alpha YP_001651618.1 657792 D 434271 CDS YP_001651619.1 165976026 5851918 658148..658672 1 NC_010278.1 lipoprotein 658672 5851918 APJL_0605 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein YP_001651619.1 658148 D 434271 CDS YP_001651620.1 165976027 5852032 complement(658945..659292) 1 NC_010278.1 transposase 659292 5852032 APJL_0606 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001651620.1 658945 R 434271 CDS YP_001651621.1 165976028 5851157 complement(659316..659639) 1 NC_010278.1 putative transposase-like protein 659639 5851157 APJL_0607 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transposase-like protein YP_001651621.1 659316 R 434271 CDS YP_001651622.1 165976029 5851803 complement(659645..660154) 1 NC_010278.1 transposase and inactivated derivative 660154 5851803 APJL_0608 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001651622.1 659645 R 434271 CDS YP_001651623.1 165976030 5851856 complement(660227..660946) 1 NC_010278.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 660946 bioD 5851856 bioD Actinobacillus pleuropneumoniae serovar 3 str. JL03 dithiobiotin synthetase YP_001651623.1 660227 R 434271 CDS YP_001651624.1 165976031 5851829 complement(661000..662190) 1 NC_010278.1 transcriptional regulator/sugar kinase 662190 mlc 5851829 mlc Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator/sugar kinase YP_001651624.1 661000 R 434271 CDS YP_001651625.1 165976032 5851762 662369..663484 1 NC_010278.1 ribonuclease D 663484 rnd 5851762 rnd Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease D YP_001651625.1 662369 D 434271 CDS YP_001651626.1 165976033 5852000 663569..664051 1 NC_010278.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 664051 lrp 5852000 lrp Actinobacillus pleuropneumoniae serovar 3 str. JL03 leucine-responsive transcriptional regulator YP_001651626.1 663569 D 434271 CDS YP_001651627.1 165976034 5851880 664117..666933 1 NC_010278.1 cell division protein 666933 ftsK 5851880 ftsK Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001651627.1 664117 D 434271 CDS YP_001651628.1 165976035 5851792 667118..667981 1 NC_010278.1 hypothetical protein 667981 5851792 APJL_0614 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651628.1 667118 D 434271 CDS YP_001651629.1 165976036 5851677 668104..669177 1 NC_010278.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 669177 aroG 5851677 aroG Actinobacillus pleuropneumoniae serovar 3 str. JL03 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001651629.1 668104 D 434271 CDS YP_001651630.1 165976037 5850990 669281..669973 1 NC_010278.1 M22 peptidase-like protein 669973 5850990 APJL_0616 Actinobacillus pleuropneumoniae serovar 3 str. JL03 M22 peptidase-like protein YP_001651630.1 669281 D 434271 CDS YP_001651631.1 165976038 5852038 complement(670415..670906) 1 NC_010278.1 thymidine kinase 670906 tdk 5852038 tdk Actinobacillus pleuropneumoniae serovar 3 str. JL03 thymidine kinase YP_001651631.1 670415 R 434271 CDS YP_001651632.1 165976039 5851874 complement(671056..671274) 1 NC_010278.1 hypothetical protein 671274 5851874 APJL_0618 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651632.1 671056 R 434271 CDS YP_001651633.1 165976040 5852070 671459..672457 1 NC_010278.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 672457 glpX 5852070 glpX Actinobacillus pleuropneumoniae serovar 3 str. JL03 fructose 1,6-bisphosphatase II YP_001651633.1 671459 D 434271 CDS YP_001651634.1 165976041 5851911 complement(672520..673293) 1 NC_010278.1 hypothetical protein 673293 5851911 APJL_0620 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651634.1 672520 R 434271 CDS YP_001651635.1 165976042 5851679 complement(673381..675303) 1 NC_010278.1 putative ABC transporter ATP-binding protein 675303 5851679 APJL_0621 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative ABC transporter ATP-binding protein YP_001651635.1 673381 R 434271 CDS YP_001651636.1 165976043 5852056 complement(675447..676847) 1 NC_010278.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 676847 cpxA 5852056 cpxA Actinobacillus pleuropneumoniae serovar 3 str. JL03 two-component sensor protein YP_001651636.1 675447 R 434271 CDS YP_001651637.1 165976044 5852102 complement(676912..677586) 1 NC_010278.1 transcriptional regulatory protein CpxR 677586 cpxR 5852102 cpxR Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulatory protein CpxR YP_001651637.1 676912 R 434271 CDS YP_001651638.1 165976045 5851730 complement(677680..678459) 1 NC_010278.1 MazG protein 678459 mazG 5851730 mazG Actinobacillus pleuropneumoniae serovar 3 str. JL03 MazG protein YP_001651638.1 677680 R 434271 CDS YP_001651639.1 165976046 5852082 678593..678694 1 NC_010278.1 hypothetical protein 678694 5852082 APJL_0625 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651639.1 678593 D 434271 CDS YP_001651640.1 165976047 5852101 678798..679691 1 NC_010278.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 679691 accD 5852101 accD Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyl-CoA carboxylase subunit beta YP_001651640.1 678798 D 434271 CDS YP_001651641.1 165976048 5852848 679748..681052 1 NC_010278.1 folylpolyglutamate synthase/dihydrofolate synthase 681052 folC 5852848 folC Actinobacillus pleuropneumoniae serovar 3 str. JL03 folylpolyglutamate synthase/dihydrofolate synthase YP_001651641.1 679748 D 434271 CDS YP_001651642.1 165976049 5852785 681436..681897 1 NC_010278.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 681897 5852785 APJL_0628 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651642.1 681436 D 434271 CDS YP_001651643.1 165976050 5852784 681914..683395 1 NC_010278.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 683395 nusA 5852784 nusA Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcription elongation factor NusA YP_001651643.1 681914 D 434271 CDS YP_001651644.1 165976051 5852781 683417..685942 1 NC_010278.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 685942 infB 5852781 infB Actinobacillus pleuropneumoniae serovar 3 str. JL03 translation initiation factor IF-2 YP_001651644.1 683417 D 434271 CDS YP_001651645.1 165976052 5852780 686114..686497 1 NC_010278.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 686497 rbfA 5852780 rbfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosome-binding factor A YP_001651645.1 686114 D 434271 CDS YP_001651646.1 165976053 5852779 686498..687415 1 NC_010278.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 687415 truB 5852779 truB Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA pseudouridine synthase B YP_001651646.1 686498 D 434271 CDS YP_001651647.1 165976054 5852778 687461..688549 1 NC_010278.1 membrane-bound lytic murein transglycosylase B 688549 5852778 APJL_0633 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane-bound lytic murein transglycosylase B YP_001651647.1 687461 D 434271 CDS YP_001651648.1 165976055 5852775 688678..688863 1 NC_010278.1 hypothetical protein 688863 5852775 APJL_0634 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651648.1 688678 D 434271 CDS YP_001651649.1 165976056 5852774 complement(688983..691121) 1 NC_010278.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 691121 pta 5852774 pta Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate acetyltransferase YP_001651649.1 688983 R 434271 CDS YP_001651650.1 165976057 5852773 complement(691177..692385) 1 NC_010278.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 692385 ackA 5852773 ackA Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetate kinase YP_001651650.1 691177 R 434271 CDS YP_001651651.1 165976058 5852772 692682..694658 1 NC_010278.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 694658 cpdB 5852772 cpdB Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_001651651.1 692682 D 434271 CDS YP_001651652.1 165976059 5852769 complement(695602..696678) 1 NC_010278.1 outer membrane protein P2-like protein 696678 ompP2B 5852769 ompP2B Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein P2-like protein YP_001651652.1 695602 R 434271 CDS YP_001651653.1 165976060 5852768 697136..697669 1 NC_010278.1 hypothetical protein 697669 5852768 APJL_0640 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651653.1 697136 D 434271 CDS YP_001651654.1 165976061 5852767 complement(697701..698588) 1 NC_010278.1 UTP-glucose-1-phosphate uridylyltransferase 698588 galU 5852767 galU Actinobacillus pleuropneumoniae serovar 3 str. JL03 UTP-glucose-1-phosphate uridylyltransferase YP_001651654.1 697701 R 434271 CDS YP_001651655.1 165976062 5852766 complement(698701..700059) 1 NC_010278.1 phosphomannomutase 700059 manB 5852766 manB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphomannomutase YP_001651655.1 698701 R 434271 CDS YP_001651656.1 165976063 5852764 complement(700094..700288) 1 NC_010278.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 700288 csrA 5852764 csrA Actinobacillus pleuropneumoniae serovar 3 str. JL03 carbon storage regulator YP_001651656.1 700094 R 434271 CDS YP_001651657.1 165976064 5852763 complement(700367..702991) 1 NC_010278.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 702991 alaS 5852763 alaS Actinobacillus pleuropneumoniae serovar 3 str. JL03 alanyl-tRNA synthetase YP_001651657.1 700367 R 434271 CDS YP_001651658.1 165976065 5852762 complement(703217..703642) 1 NC_010278.1 universal stress protein A 703642 uspA 5852762 uspA Actinobacillus pleuropneumoniae serovar 3 str. JL03 universal stress protein A YP_001651658.1 703217 R 434271 CDS YP_001651659.1 165976066 5852761 703906..704673 1 NC_010278.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 704673 hlyX 5852761 hlyX Actinobacillus pleuropneumoniae serovar 3 str. JL03 fumarate/nitrate reduction transcriptional regulator YP_001651659.1 703906 D 434271 CDS YP_001651660.1 165976067 5852760 complement(704772..705188) 1 NC_010278.1 ClpXP protease specificity-enhancing factor 705188 sspB 5852760 sspB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ClpXP protease specificity-enhancing factor YP_001651660.1 704772 R 434271 CDS YP_001651661.1 165976068 5852759 complement(705188..705832) 1 NC_010278.1 stringent starvation protein A 705832 sspA 5852759 sspA Actinobacillus pleuropneumoniae serovar 3 str. JL03 stringent starvation protein A YP_001651661.1 705188 R 434271 CDS YP_001651662.1 165976069 5852758 706051..706545 1 NC_010278.1 phosphoribosylaminoimidazole carboxylasecatalytic subunit 706545 purE 5852758 purE Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylaminoimidazole carboxylasecatalytic subunit YP_001651662.1 706051 D 434271 CDS YP_001651663.1 165976070 5852757 706555..707520 1 NC_010278.1 L-asparaginase 707520 5852757 APJL_0650 Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-asparaginase YP_001651663.1 706555 D 434271 CDS YP_001651664.1 165976071 5852756 707630..708718 1 NC_010278.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 708718 purK 5852756 purK Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001651664.1 707630 D 434271 CDS YP_001651665.1 165976072 5852755 708850..710046 1 NC_010278.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 710046 aspC 5852755 aspC Actinobacillus pleuropneumoniae serovar 3 str. JL03 aromatic amino acid aminotransferase YP_001651665.1 708850 D 434271 CDS YP_001651666.1 165976073 5852754 complement(710230..711516) 1 NC_010278.1 Xaa-Pro aminopeptidase 711516 pepP 5852754 pepP Actinobacillus pleuropneumoniae serovar 3 str. JL03 Xaa-Pro aminopeptidase YP_001651666.1 710230 R 434271 CDS YP_001651667.1 165976074 5852753 complement(711644..714661) 1 NC_010278.1 type III restriction-modification system restriction subunit 714661 5852753 APJL_0654 Actinobacillus pleuropneumoniae serovar 3 str. JL03 type III restriction-modification system restriction subunit YP_001651667.1 711644 R 434271 CDS YP_001651668.1 165976075 5852752 complement(714681..716537) 1 NC_010278.1 type III restriction-modification system methyltransferase 716537 5852752 APJL_0655 Actinobacillus pleuropneumoniae serovar 3 str. JL03 type III restriction-modification system methyltransferase YP_001651668.1 714681 R 434271 CDS YP_001651669.1 165976076 5852751 complement(716552..717244) 1 NC_010278.1 hypothetical protein 717244 5852751 APJL_0656 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651669.1 716552 R 434271 CDS YP_001651670.1 165976077 5852749 complement(717247..720522) 1 NC_010278.1 hypothetical protein 720522 5852749 APJL_0657 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651670.1 717247 R 434271 CDS YP_001651671.1 165976078 5852748 complement(720648..721871) 1 NC_010278.1 hypothetical protein 721871 5852748 APJL_0658 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651671.1 720648 R 434271 CDS YP_001651672.1 165976079 5852747 complement(722007..722396) 1 NC_010278.1 hypothetical protein 722396 5852747 APJL_0659 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651672.1 722007 R 434271 CDS YP_001651673.1 165976080 5852746 complement(722397..722657) 1 NC_010278.1 hypothetical protein 722657 5852746 APJL_0660 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651673.1 722397 R 434271 CDS YP_001651674.1 165976081 5852745 723003..723839 1 NC_010278.1 hypothetical protein 723839 5852745 APJL_0661 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651674.1 723003 D 434271 CDS YP_001651675.1 165976082 5852744 complement(723871..725892) 1 NC_010278.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 725892 uvrB 5852744 uvrB Actinobacillus pleuropneumoniae serovar 3 str. JL03 excinuclease ABC subunit B YP_001651675.1 723871 R 434271 CDS YP_001651676.1 165976083 5852743 726069..726881 1 NC_010278.1 lipoprotein precursor 726881 5852743 APJL_0663 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein precursor YP_001651676.1 726069 D 434271 CDS YP_001651677.1 165976084 5852740 726896..728086 1 NC_010278.1 putative peroxidase YwbN 728086 ywbN 5852740 ywbN Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative peroxidase YwbN YP_001651677.1 726896 D 434271 CDS YP_001651678.1 165976085 5852739 728097..728717 1 NC_010278.1 high-affinity Fe2+/Pb2+ permease 728717 5852739 APJL_0665 Actinobacillus pleuropneumoniae serovar 3 str. JL03 high-affinity Fe2+/Pb2+ permease YP_001651678.1 728097 D 434271 CDS YP_001651679.1 165976086 5852737 complement(728757..729575) 1 NC_010278.1 metal-dependent phosphoesterase 729575 trpH 5852737 trpH Actinobacillus pleuropneumoniae serovar 3 str. JL03 metal-dependent phosphoesterase YP_001651679.1 728757 R 434271 CDS YP_001651680.1 165976087 5852736 complement(729579..730169) 1 NC_010278.1 Mug protein 730169 5852736 APJL_0667 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Mug protein YP_001651680.1 729579 R 434271 CDS YP_001651681.1 165976088 5852735 complement(730186..731730) 1 NC_010278.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 731730 sbcB 5852735 sbcB Actinobacillus pleuropneumoniae serovar 3 str. JL03 exonuclease I YP_001651681.1 730186 R 434271 CDS YP_001651682.1 165976089 5852734 complement(731972..733252) 1 NC_010278.1 chloride channel protein 733252 eriC 5852734 eriC Actinobacillus pleuropneumoniae serovar 3 str. JL03 chloride channel protein YP_001651682.1 731972 R 434271 CDS YP_001651683.1 165976090 5852733 733586..734989 1 NC_010278.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 734989 asnC 5852733 asnC Actinobacillus pleuropneumoniae serovar 3 str. JL03 asparaginyl-tRNA synthetase YP_001651683.1 733586 D 434271 CDS YP_001651684.1 165976091 5852732 complement(735093..736094) 1 NC_010278.1 hypothetical protein 736094 5852732 APJL_0671 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651684.1 735093 R 434271 CDS YP_001651685.1 165976092 5852731 complement(736181..736744) 1 NC_010278.1 hypothetical protein 736744 5852731 APJL_0672 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651685.1 736181 R 434271 CDS YP_001651686.1 165976093 5852729 736822..737460 1 NC_010278.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 737460 efp 5852729 efp Actinobacillus pleuropneumoniae serovar 3 str. JL03 elongation factor P YP_001651686.1 736822 D 434271 CDS YP_001651687.1 165976094 5852728 737615..739285 1 NC_010278.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 739285 glnS 5852728 glnS Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutaminyl-tRNA synthetase YP_001651687.1 737615 D 434271 CDS YP_001651688.1 165976095 5852727 739288..739482 1 NC_010278.1 hypothetical protein 739482 5852727 APJL_0675 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651688.1 739288 D 434271 CDS YP_001651689.1 165976096 5852726 complement(739515..740906) 1 NC_010278.1 putative transport protein 740906 5852726 APJL_0676 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transport protein YP_001651689.1 739515 R 434271 CDS YP_001651690.1 165976097 5852725 complement(741087..743195) 1 NC_010278.1 putative soluble lytic murein transglycosylase 743195 5852725 APJL_0677 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative soluble lytic murein transglycosylase YP_001651690.1 741087 R 434271 CDS YP_001651691.1 165976098 5852723 complement(743304..743843) 1 NC_010278.1 hypoxanthine phosphoribosyl transferase 743843 hpt 5852723 hpt Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypoxanthine phosphoribosyl transferase YP_001651691.1 743304 R 434271 CDS YP_001651692.1 165976099 5852721 complement(743947..745083) 1 NC_010278.1 catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase 745083 metB 5852721 metB Actinobacillus pleuropneumoniae serovar 3 str. JL03 cystathionine gamma-synthase YP_001651692.1 743947 R 434271 CDS YP_001651693.1 165976100 5852720 complement(745197..746006) 1 NC_010278.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 746006 dapB 5852720 dapB Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydrodipicolinate reductase YP_001651693.1 745197 R 434271 CDS YP_001651694.1 165976101 5852719 complement(746065..746640) 1 NC_010278.1 hypothetical protein 746640 5852719 APJL_0681 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651694.1 746065 R 434271 CDS YP_001651695.1 165976102 5852718 complement(746640..747557) 1 NC_010278.1 hypothetical protein 747557 5852718 APJL_0682 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651695.1 746640 R 434271 CDS YP_001651696.1 165976103 5852717 complement(747582..748667) 1 NC_010278.1 putative RNA 2'-O-ribose methyltransferase 748667 mtfA 5852717 mtfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative RNA 2'-O-ribose methyltransferase YP_001651696.1 747582 R 434271 CDS YP_001651697.1 165976104 5852716 complement(749039..749443) 1 NC_010278.1 membrane protein 749443 5852716 APJL_0684 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane protein YP_001651697.1 749039 R 434271 CDS YP_001651698.1 165976105 5852715 749547..751238 1 NC_010278.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 751238 dld 5852715 dld Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-lactate dehydrogenase YP_001651698.1 749547 D 434271 CDS YP_001651699.1 165976106 5852714 complement(751376..753850) 1 NC_010278.1 trimethylamine-N-oxide reductase 2 753850 torZ 5852714 torZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 trimethylamine-N-oxide reductase 2 YP_001651699.1 751376 R 434271 CDS YP_001651700.1 165976107 5852713 complement(754046..755164) 1 NC_010278.1 cytochrome c-type protein TorY 755164 torY 5852713 torY Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c-type protein TorY YP_001651700.1 754046 R 434271 CDS YP_001651701.1 165976108 5852711 755516..756538 1 NC_010278.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 756538 moaA 5852711 moaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdenum cofactor biosynthesis protein A YP_001651701.1 755516 D 434271 CDS YP_001651702.1 165976109 5852709 756823..757299 1 NC_010278.1 molybdenum cofactor biosynthesis protein C 757299 moaC 5852709 moaC Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdenum cofactor biosynthesis protein C YP_001651702.1 756823 D 434271 CDS YP_001651703.1 165976110 5852708 757321..757566 1 NC_010278.1 molybdopterin converting factor, small subunit 757566 moaD 5852708 moaD Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdopterin converting factor, small subunit YP_001651703.1 757321 D 434271 CDS YP_001651704.1 165976111 5852706 757567..758022 1 NC_010278.1 molybdopterin converting factor subunit 2 758022 moaE 5852706 moaE Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdopterin converting factor subunit 2 YP_001651704.1 757567 D 434271 CDS YP_001651705.1 165976112 5852704 758103..758594 1 NC_010278.1 putative metalloprotease 758594 5852704 APJL_0692 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative metalloprotease YP_001651705.1 758103 D 434271 CDS YP_001651706.1 165976113 5852703 758606..760396 1 NC_010278.1 acetyltransferase 760396 5852703 APJL_0693 Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyltransferase YP_001651706.1 758606 D 434271 CDS YP_001651707.1 165976114 5852702 complement(760460..763069) 1 NC_010278.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 763069 topA 5852702 topA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA topoisomerase I YP_001651707.1 760460 R 434271 CDS YP_001651708.1 165976115 5852701 763211..764107 1 NC_010278.1 putative HTH-type transcriptional regulator 764107 5852701 APJL_0695 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative HTH-type transcriptional regulator YP_001651708.1 763211 D 434271 CDS YP_001651709.1 165976116 5852700 complement(764199..765512) 1 NC_010278.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 765512 argA 5852700 argA Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetylglutamate synthase YP_001651709.1 764199 R 434271 CDS YP_001651710.1 165976117 5852699 complement(765660..766958) 1 NC_010278.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 766958 aroA 5852699 aroA Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-phosphoshikimate 1-carboxyvinyltransferase YP_001651710.1 765660 R 434271 CDS YP_001651711.1 165976118 5852697 complement(766972..768066) 1 NC_010278.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 768066 hisC1 5852697 hisC1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 histidinol-phosphate aminotransferase YP_001651711.1 766972 R 434271 CDS YP_001651712.1 165976119 5852695 complement(768266..769534) 1 NC_010278.1 putative cystathionine beta-lyase 769534 metC2 5852695 metC2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative cystathionine beta-lyase YP_001651712.1 768266 R 434271 CDS YP_001651713.1 165976120 5852693 complement(769740..770828) 1 NC_010278.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 770828 serC 5852693 serC Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoserine aminotransferase YP_001651713.1 769740 R 434271 CDS YP_001651714.1 165976121 5852690 complement(773891..777208) 1 NC_010278.1 potential type III restriction enzyme 777208 5852690 APJL_0703 Actinobacillus pleuropneumoniae serovar 3 str. JL03 potential type III restriction enzyme YP_001651714.1 773891 R 434271 CDS YP_001651715.1 165976122 5852689 complement(777610..780498) 1 NC_010278.1 methylation subunit, type III restriction-modification system 780498 5852689 APJL_0704 Actinobacillus pleuropneumoniae serovar 3 str. JL03 methylation subunit, type III restriction-modification system YP_001651715.1 777610 R 434271 CDS YP_001651716.1 165976123 5852688 complement(780823..781695) 1 NC_010278.1 putative HTH-type transcriptional regulator 781695 5852688 APJL_0705 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative HTH-type transcriptional regulator YP_001651716.1 780823 R 434271 CDS YP_001651717.1 165976124 5852687 complement(781705..782172) 1 NC_010278.1 hypothetical protein 782172 5852687 APJL_0706 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651717.1 781705 R 434271 CDS YP_001651718.1 165976125 5852686 complement(782373..783881) 1 NC_010278.1 exopolyphosphatase 783881 ppx 5852686 ppx Actinobacillus pleuropneumoniae serovar 3 str. JL03 exopolyphosphatase YP_001651718.1 782373 R 434271 CDS YP_001651719.1 165976126 5852684 784090..784425 1 NC_010278.1 hypothetical protein 784425 5852684 APJL_0708 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651719.1 784090 D 434271 CDS YP_001651720.1 165976127 5852682 complement(786396..786845) 1 NC_010278.1 transcriptional regulator NrdR 786845 nrdR 5852682 nrdR Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator NrdR YP_001651720.1 786396 R 434271 CDS YP_001651721.1 165976128 5852680 complement(786845..787132) 1 NC_010278.1 hypothetical protein 787132 5852680 APJL_0712 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651721.1 786845 R 434271 CDS YP_001651722.1 165976129 5852678 complement(787104..788585) 1 NC_010278.1 replicative DNA helicase 788585 dnaB2 5852678 dnaB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 replicative DNA helicase YP_001651722.1 787104 R 434271 CDS YP_001651723.1 165976130 5852677 788765..789673 1 NC_010278.1 enterochelin ABC transporter,periplasmic protein 789673 5852677 APJL_0714 Actinobacillus pleuropneumoniae serovar 3 str. JL03 enterochelin ABC transporter,periplasmic protein YP_001651723.1 788765 D 434271 CDS YP_001651724.1 165976131 5852675 789760..790707 1 NC_010278.1 iron(III) transport system permease 790707 5852675 APJL_0715 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron(III) transport system permease YP_001651724.1 789760 D 434271 CDS YP_001651725.1 165976132 5852674 790707..791648 1 NC_010278.1 iron(III) transport system permease 791648 5852674 APJL_0716 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron(III) transport system permease YP_001651725.1 790707 D 434271 CDS YP_001651726.1 165976133 5852673 791650..792408 1 NC_010278.1 iron(III) transport system ATP-binding protein 792408 5852673 APJL_0717 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron(III) transport system ATP-binding protein YP_001651726.1 791650 D 434271 CDS YP_001651727.1 165976134 5852671 792597..793277 1 NC_010278.1 phosphate transport regulator 793277 5852671 APJL_0718 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate transport regulator YP_001651727.1 792597 D 434271 CDS YP_001651728.1 165976135 5852670 793287..794549 1 NC_010278.1 putative phosphate permease 794549 5852670 APJL_0719 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative phosphate permease YP_001651728.1 793287 D 434271 CDS YP_001651729.1 165976136 5852669 794613..795218 1 NC_010278.1 SH3 domain-containing protein 795218 5852669 APJL_0720 Actinobacillus pleuropneumoniae serovar 3 str. JL03 SH3 domain-containing protein YP_001651729.1 794613 D 434271 CDS YP_001651730.1 165976137 5852667 complement(795271..795498) 1 NC_010278.1 hypothetical protein 795498 5852667 APJL_0721 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651730.1 795271 R 434271 CDS YP_001651731.1 165976138 5852666 complement(795505..796020) 1 NC_010278.1 hypothetical protein 796020 5852666 APJL_0722 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651731.1 795505 R 434271 CDS YP_001651732.1 165976139 5852665 complement(796093..797241) 1 NC_010278.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 797241 tgt 5852665 tgt Actinobacillus pleuropneumoniae serovar 3 str. JL03 queuine tRNA-ribosyltransferase YP_001651732.1 796093 R 434271 CDS YP_001651733.1 165976140 5852664 complement(797313..797489) 1 NC_010278.1 hypothetical protein 797489 5852664 APJL_0724 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651733.1 797313 R 434271 CDS YP_001651734.1 165976141 5852663 797564..798136 1 NC_010278.1 hypothetical protein 798136 5852663 APJL_0725 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651734.1 797564 D 434271 CDS YP_001651735.1 165976142 5852662 798244..798450 1 NC_010278.1 cold shock-like protein CspD 798450 cspD 5852662 cspD Actinobacillus pleuropneumoniae serovar 3 str. JL03 cold shock-like protein CspD YP_001651735.1 798244 D 434271 CDS YP_001651736.1 165976143 5852660 799600..801324 1 NC_010278.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 3 catalytic subunit 801324 ilvI 5852660 ilvI Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetolactate synthase 3 catalytic subunit YP_001651736.1 799600 D 434271 CDS YP_001651737.1 165976144 5852658 801317..801808 1 NC_010278.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 801808 ilvH 5852658 ilvH Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetolactate synthase 3 regulatory subunit YP_001651737.1 801317 D 434271 CDS YP_001651738.1 165976145 5852657 complement(802078..803427) 1 NC_010278.1 antibiotic maturation factor PmbA 803427 pmbA 5852657 pmbA Actinobacillus pleuropneumoniae serovar 3 str. JL03 antibiotic maturation factor PmbA YP_001651738.1 802078 R 434271 CDS YP_001651739.1 165976146 5852656 803535..804065 1 NC_010278.1 hypothetical protein 804065 5852656 APJL_0732 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651739.1 803535 D 434271 CDS YP_001651740.1 165976147 5852654 804110..804481 1 NC_010278.1 hypothetical protein 804481 5852654 APJL_0733 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651740.1 804110 D 434271 CDS YP_001651741.1 165976148 5852651 804664..805113 1 NC_010278.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 805113 ubiX 5852651 ubiX Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001651741.1 804664 D 434271 CDS YP_001651742.1 165976149 5852649 805116..805829 1 NC_010278.1 putative inner membrane protein 805829 yqgA 5852649 yqgA Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative inner membrane protein YP_001651742.1 805116 D 434271 CDS YP_001651743.1 165976150 5852648 805876..806325 1 NC_010278.1 hypothetical protein 806325 5852648 APJL_0736 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651743.1 805876 D 434271 CDS YP_001651744.1 165976151 5852647 complement(806398..806709) 1 NC_010278.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 806709 5852647 APJL_0737 Actinobacillus pleuropneumoniae serovar 3 str. JL03 translation initiation factor Sui1 YP_001651744.1 806398 R 434271 CDS YP_001651745.1 165976152 5852646 complement(806789..807481) 1 NC_010278.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 807481 pyrF 5852646 pyrF Actinobacillus pleuropneumoniae serovar 3 str. JL03 orotidine 5'-phosphate decarboxylase YP_001651745.1 806789 R 434271 CDS YP_001651746.1 165976153 5852645 complement(807506..808702) 1 NC_010278.1 tetratricopeptide repeat protein 808702 5852645 APJL_0739 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tetratricopeptide repeat protein YP_001651746.1 807506 R 434271 CDS YP_001651747.1 165976154 5852644 complement(808702..808992) 1 NC_010278.1 hypothetical protein 808992 5852644 APJL_0740 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651747.1 808702 R 434271 CDS YP_001651748.1 165976155 5852643 complement(809061..809342) 1 NC_010278.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 809342 ihfB 5852643 ihfB Actinobacillus pleuropneumoniae serovar 3 str. JL03 integration host factor subunit beta YP_001651748.1 809061 R 434271 CDS YP_001651749.1 165976156 5852642 complement(809416..811080) 1 NC_010278.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 811080 rpsA 5852642 rpsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S1 YP_001651749.1 809416 R 434271 CDS YP_001651750.1 165976157 5852640 complement(811177..811851) 1 NC_010278.1 cytidylate kinase 811851 cmkA 5852640 cmkA Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytidylate kinase YP_001651750.1 811177 R 434271 CDS YP_001651751.1 165976158 5852639 complement(812097..812912) 1 NC_010278.1 protease DegS 812912 degS 5852639 degS Actinobacillus pleuropneumoniae serovar 3 str. JL03 protease DegS YP_001651751.1 812097 R 434271 CDS YP_001651752.1 165976159 5852637 complement(813161..813487) 1 NC_010278.1 preprotein translocase subunit SecG 813487 secG 5852637 secG Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit SecG YP_001651752.1 813161 R 434271 CDS YP_001651753.1 165976160 5852636 complement(813619..815535) 1 NC_010278.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 815535 topB2 5852636 topB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA topoisomerase III YP_001651753.1 813619 R 434271 CDS YP_001651754.1 165976161 5852635 815718..817163 1 NC_010278.1 alkaline phosphatase 817163 5852635 APJL_0747 Actinobacillus pleuropneumoniae serovar 3 str. JL03 alkaline phosphatase YP_001651754.1 815718 D 434271 CDS YP_001651755.1 165976162 5852634 complement(817212..818042) 1 NC_010278.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 818042 mepA 5852634 mepA Actinobacillus pleuropneumoniae serovar 3 str. JL03 penicillin-insensitive murein endopeptidase YP_001651755.1 817212 R 434271 CDS YP_001651756.1 165976163 5852632 complement(818137..819219) 1 NC_010278.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 819219 aroC 5852632 aroC Actinobacillus pleuropneumoniae serovar 3 str. JL03 chorismate synthase YP_001651756.1 818137 R 434271 CDS YP_001651757.1 165976164 5852631 complement(819241..822549) 1 NC_010278.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 822549 kefA1 5852631 kefA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 potassium efflux protein KefA YP_001651757.1 819241 R 434271 CDS YP_001651758.1 165976165 5852630 complement(822567..825911) 1 NC_010278.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 825911 kefA2 5852630 kefA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 potassium efflux protein KefA YP_001651758.1 822567 R 434271 CDS YP_001651759.1 165976166 5852629 complement(825892..827322) 1 NC_010278.1 O-succinylbenzoic acid--CoA ligase 827322 menE 5852629 menE Actinobacillus pleuropneumoniae serovar 3 str. JL03 O-succinylbenzoic acid--CoA ligase YP_001651759.1 825892 R 434271 CDS YP_001651760.1 165976167 5852628 complement(827340..827900) 1 NC_010278.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 827900 seqA 5852628 seqA Actinobacillus pleuropneumoniae serovar 3 str. JL03 replication initiation regulator SeqA YP_001651760.1 827340 R 434271 CDS YP_001651761.1 165976168 5852626 828024..828809 1 NC_010278.1 putative esterase/lipase 828809 5852626 APJL_0754 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative esterase/lipase YP_001651761.1 828024 D 434271 CDS YP_001651762.1 165976169 5852624 828817..829542 1 NC_010278.1 SAM-dependent methyltransferase 829542 5852624 APJL_0755 Actinobacillus pleuropneumoniae serovar 3 str. JL03 SAM-dependent methyltransferase YP_001651762.1 828817 D 434271 CDS YP_001651763.1 165976170 5852623 829746..830534 1 NC_010278.1 enoyl-(acyl carrier protein) reductase 830534 fabI 5852623 fabI Actinobacillus pleuropneumoniae serovar 3 str. JL03 enoyl-(acyl carrier protein) reductase YP_001651763.1 829746 D 434271 CDS YP_001651764.1 165976171 5852622 830729..831007 1 NC_010278.1 hypothetical protein 831007 5852622 APJL_0757 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651764.1 830729 D 434271 CDS YP_001651765.1 165976172 5852620 830982..831260 1 NC_010278.1 hypothetical protein 831260 5852620 APJL_0758 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651765.1 830982 D 434271 CDS YP_001651766.1 165976173 5852619 831392..833368 1 NC_010278.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 833368 rnb 5852619 rnb Actinobacillus pleuropneumoniae serovar 3 str. JL03 exoribonuclease II YP_001651766.1 831392 D 434271 CDS YP_001651767.1 165976174 5852617 833443..833814 1 NC_010278.1 putative effector of murein hydrolase LrgA 833814 lrgA1 5852617 lrgA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative effector of murein hydrolase LrgA YP_001651767.1 833443 D 434271 CDS YP_001651768.1 165976175 5852615 833811..834497 1 NC_010278.1 putative effector of murein hydrolase 834497 lrgB 5852615 lrgB Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative effector of murein hydrolase YP_001651768.1 833811 D 434271 CDS YP_001651769.1 165976176 5852614 834522..835334 1 NC_010278.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 835334 apaH 5852614 apaH Actinobacillus pleuropneumoniae serovar 3 str. JL03 diadenosine tetraphosphatase YP_001651769.1 834522 D 434271 CDS YP_001651770.1 165976177 5852610 complement(835523..835765) 1 NC_010278.1 hypothetical protein 835765 5852610 APJL_0763 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651770.1 835523 R 434271 CDS YP_001651771.1 165976178 5852609 835933..836688 1 NC_010278.1 SAM-dependent methyltransferase 836688 5852609 APJL_0764 Actinobacillus pleuropneumoniae serovar 3 str. JL03 SAM-dependent methyltransferase YP_001651771.1 835933 D 434271 CDS YP_001651772.1 165976179 5852607 836747..837808 1 NC_010278.1 putative permease 837808 perM 5852607 perM Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative permease YP_001651772.1 836747 D 434271 CDS YP_001651773.1 165976180 5852605 837838..838767 1 NC_010278.1 hypothetical protein 838767 5852605 APJL_0766 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651773.1 837838 D 434271 CDS YP_001651774.1 165976181 5852604 838815..839900 1 NC_010278.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 839900 queA 5852604 queA Actinobacillus pleuropneumoniae serovar 3 str. JL03 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001651774.1 838815 D 434271 CDS YP_001651775.1 165976182 5852603 complement(839934..842228) 1 NC_010278.1 recombination protein 2 842228 rec2 5852603 rec2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 recombination protein 2 YP_001651775.1 839934 R 434271 CDS YP_001651776.1 165976183 5852602 complement(842328..843542) 1 NC_010278.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 843542 5852602 APJL_0769 Actinobacillus pleuropneumoniae serovar 3 str. JL03 serine/threonine transporter SstT YP_001651776.1 842328 R 434271 CDS YP_001651777.1 165976184 5852601 843791..844153 1 NC_010278.1 diacylglycerol kinase 844153 dgkA 5852601 dgkA Actinobacillus pleuropneumoniae serovar 3 str. JL03 diacylglycerol kinase YP_001651777.1 843791 D 434271 CDS YP_001651778.1 165976185 5852599 844234..845877 1 NC_010278.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 845877 ushA 5852599 ushA Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_001651778.1 844234 D 434271 CDS YP_001651779.1 165976186 5852598 845956..846255 1 NC_010278.1 hypothetical protein 846255 5852598 APJL_0772 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651779.1 845956 D 434271 CDS YP_001651780.1 165976187 5852597 846384..846749 1 NC_010278.1 hypothetical protein 846749 5852597 APJL_0773 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651780.1 846384 D 434271 CDS YP_001651781.1 165976188 5852591 complement(847458..848882) 1 NC_010278.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 848882 lpdA 5852591 lpdA Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydrolipoamide dehydrogenase YP_001651781.1 847458 R 434271 CDS YP_001651782.1 165976189 5852589 complement(848978..850876) 1 NC_010278.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 850876 aceF 5852589 aceF Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydrolipoamide acetyltransferase YP_001651782.1 848978 R 434271 CDS YP_001651783.1 165976190 5852588 complement(850936..853590) 1 NC_010278.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 853590 aceE 5852588 aceE Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyruvate dehydrogenase subunit E1 YP_001651783.1 850936 R 434271 CDS YP_001651784.1 165976191 5852587 complement(853945..854952) 1 NC_010278.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 854952 pyrD 5852587 pyrD Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydroorotate dehydrogenase 2 YP_001651784.1 853945 R 434271 CDS YP_001651785.1 165976192 5852586 complement(855026..855976) 1 NC_010278.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 855976 prsA 5852586 prsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribose-phosphate pyrophosphokinase YP_001651785.1 855026 R 434271 CDS YP_001651786.1 165976193 5852585 complement(855988..856845) 1 NC_010278.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 856845 ipk 5852585 ipk Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001651786.1 855988 R 434271 CDS YP_001651787.1 165976194 5852584 complement(856855..857487) 1 NC_010278.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 857487 lolB 5852584 lolB Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane lipoprotein LolB YP_001651787.1 856855 R 434271 CDS YP_001651788.1 165976195 5852583 complement(857616..859364) 1 NC_010278.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 859364 msbA 5852583 msbA Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipid transporter ATP-binding/permease YP_001651788.1 857616 R 434271 CDS YP_001651789.1 165976196 5852582 complement(859469..860155) 1 NC_010278.1 putative effector of murein hydrolase 860155 5852582 APJL_0782 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative effector of murein hydrolase YP_001651789.1 859469 R 434271 CDS YP_001651790.1 165976197 5852581 complement(860165..860524) 1 NC_010278.1 putative effector of murein hydrolase LrgA 860524 lrgA2 5852581 lrgA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative effector of murein hydrolase LrgA YP_001651790.1 860165 R 434271 CDS YP_001651791.1 165976198 5852580 complement(860591..862513) 1 NC_010278.1 ATP-dependent helicase 862513 5852580 APJL_0784 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent helicase YP_001651791.1 860591 R 434271 CDS YP_001651792.1 165976199 5852579 862635..862847 1 NC_010278.1 hypothetical protein 862847 5852579 APJL_0785 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651792.1 862635 D 434271 CDS YP_001651793.1 165976200 5852578 complement(862986..865814) 1 NC_010278.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 865814 uvrA 5852578 uvrA Actinobacillus pleuropneumoniae serovar 3 str. JL03 excinuclease ABC subunit A YP_001651793.1 862986 R 434271 CDS YP_001651794.1 165976201 5852577 865965..866489 1 NC_010278.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 866489 ssb 5852577 ssb Actinobacillus pleuropneumoniae serovar 3 str. JL03 single-stranded DNA-binding protein YP_001651794.1 865965 D 434271 CDS YP_001651795.1 165976202 5852575 complement(866653..867471) 1 NC_010278.1 hypothetical protein 867471 5852575 APJL_0788 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651795.1 866653 R 434271 CDS YP_001651796.1 165976203 5852574 complement(867794..869785) 1 NC_010278.1 hypothetical protein 869785 5852574 APJL_0789 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651796.1 867794 R 434271 CDS YP_001651797.1 165976204 5852573 complement(869782..870210) 1 NC_010278.1 hypothetical protein 870210 5852573 APJL_0790 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651797.1 869782 R 434271 CDS YP_001651798.1 165976205 5852572 complement(870207..871295) 1 NC_010278.1 hypothetical protein 871295 5852572 APJL_0791 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651798.1 870207 R 434271 CDS YP_001651799.1 165976206 5852570 complement(871396..872688) 1 NC_010278.1 putative ATPase 872688 5852570 APJL_0792 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative ATPase YP_001651799.1 871396 R 434271 CDS YP_001651800.1 165976207 5852568 complement(872996..873883) 1 NC_010278.1 transcriptional regulator 873883 5852568 APJL_0793 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001651800.1 872996 R 434271 CDS YP_001651801.1 165976208 5852567 873988..874962 1 NC_010278.1 dioxygenase 874962 5852567 APJL_0794 Actinobacillus pleuropneumoniae serovar 3 str. JL03 dioxygenase YP_001651801.1 873988 D 434271 CDS YP_001651802.1 165976209 5852564 complement(876908..877675) 1 NC_010278.1 hypothetical protein 877675 5852564 APJL_0798 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651802.1 876908 R 434271 CDS YP_001651803.1 165976210 5852563 complement(877758..878732) 1 NC_010278.1 peptide transport system ATP binding protein 878732 sapD 5852563 sapD Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide transport system ATP binding protein YP_001651803.1 877758 R 434271 CDS YP_001651804.1 165976211 5852562 complement(878809..879696) 1 NC_010278.1 peptide transport system permease 879696 sapC 5852562 sapC Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide transport system permease YP_001651804.1 878809 R 434271 CDS YP_001651805.1 165976212 5852559 complement(879686..880648) 1 NC_010278.1 peptide transport system permease 880648 sapB 5852559 sapB Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide transport system permease YP_001651805.1 879686 R 434271 CDS YP_001651806.1 165976213 5852558 complement(880648..882345) 1 NC_010278.1 peptide transport periplasmic protein 882345 sapA 5852558 sapA Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide transport periplasmic protein YP_001651806.1 880648 R 434271 CDS YP_001651807.1 165976214 5852557 complement(882355..883503) 1 NC_010278.1 transcriptional regulatory protein 883503 tyrR 5852557 tyrR Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulatory protein YP_001651807.1 882355 R 434271 CDS YP_001651808.1 165976215 5852556 883708..884292 1 NC_010278.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 884292 gmhA 5852556 gmhA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoheptose isomerase YP_001651808.1 883708 D 434271 CDS YP_001651809.1 165976216 5852554 complement(884525..886135) 1 NC_010278.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 886135 pckA 5852554 pckA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoenolpyruvate carboxykinase YP_001651809.1 884525 R 434271 CDS YP_001651810.1 165976217 5852552 886408..886686 1 NC_010278.1 cell division protein FtsB 886686 ftsB 5852552 ftsB Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein FtsB YP_001651810.1 886408 D 434271 CDS YP_001651811.1 165976218 5852551 886702..887388 1 NC_010278.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 887388 ispD 5852551 ispD Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001651811.1 886702 D 434271 CDS YP_001651812.1 165976219 5852550 887385..887861 1 NC_010278.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 887861 ispF 5852550 ispF Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001651812.1 887385 D 434271 CDS YP_001651813.1 165976220 5852548 complement(887895..888014) 1 NC_010278.1 hypothetical protein 888014 5852548 APJL_0809 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651813.1 887895 R 434271 CDS YP_001651814.1 165976221 5852547 complement(888530..890506) 1 NC_010278.1 hypothetical protein 890506 5852547 APJL_0810 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651814.1 888530 R 434271 CDS YP_001651815.1 165976222 5852546 complement(890544..891332) 1 NC_010278.1 putative Fe-S protein 891332 ycbX 5852546 ycbX Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative Fe-S protein YP_001651815.1 890544 R 434271 CDS YP_001651816.1 165976223 5852545 891477..891701 1 NC_010278.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 891701 5852545 APJL_0812 Actinobacillus pleuropneumoniae serovar 3 str. JL03 exodeoxyribonuclease VII small subunit YP_001651816.1 891477 D 434271 CDS YP_001651817.1 165976224 5852544 891710..892603 1 NC_010278.1 geranyltranstransferase 892603 ispA 5852544 ispA Actinobacillus pleuropneumoniae serovar 3 str. JL03 geranyltranstransferase YP_001651817.1 891710 D 434271 CDS YP_001651818.1 165976225 5852543 complement(892687..893031) 1 NC_010278.1 hypothetical protein 893031 5852543 APJL_0814 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651818.1 892687 R 434271 CDS YP_001651819.1 165976226 5852542 complement(893132..894634) 1 NC_010278.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 894634 lysS 5852542 lysS Actinobacillus pleuropneumoniae serovar 3 str. JL03 lysyl-tRNA synthetase YP_001651819.1 893132 R 434271 CDS YP_001651820.1 165976227 5852541 complement(894769..896244) 1 NC_010278.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 896244 cafA 5852541 cafA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease G YP_001651820.1 894769 R 434271 CDS YP_001651821.1 165976228 5852540 896474..898237 1 NC_010278.1 hypothetical protein 898237 5852540 APJL_0817 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651821.1 896474 D 434271 CDS YP_001651822.1 165976229 5852538 complement(898270..900882) 1 NC_010278.1 type III restriction enzyme 900882 5852538 APJL_0818 Actinobacillus pleuropneumoniae serovar 3 str. JL03 type III restriction enzyme YP_001651822.1 898270 R 434271 CDS YP_001651823.1 165976230 5852536 complement(901021..902868) 1 NC_010278.1 adenine specific DNA methylase Mod 902868 5852536 APJL_0819 Actinobacillus pleuropneumoniae serovar 3 str. JL03 adenine specific DNA methylase Mod YP_001651823.1 901021 R 434271 CDS YP_001651824.1 165976231 5852535 903123..904085 1 NC_010278.1 hypothetical protein 904085 5852535 APJL_0820 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651824.1 903123 D 434271 CDS YP_001651825.1 165976232 5852534 904231..904566 1 NC_010278.1 hypothetical protein 904566 5852534 APJL_0821 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651825.1 904231 D 434271 CDS YP_001651826.1 165976233 5852533 complement(904633..905730) 1 NC_010278.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 905730 mltA 5852533 mltA Actinobacillus pleuropneumoniae serovar 3 str. JL03 murein transglycosylase A YP_001651826.1 904633 R 434271 CDS YP_001651827.1 165976234 5852527 complement(907975..908388) 1 NC_010278.1 transthyretin-like periplasmic protein 908388 5852527 APJL_0825 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transthyretin-like periplasmic protein YP_001651827.1 907975 R 434271 CDS YP_001651828.1 165976235 5852526 908587..909597 1 NC_010278.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 909597 purR1 5852526 purR1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding transcriptional repressor PurR YP_001651828.1 908587 D 434271 CDS YP_001651829.1 165976236 5852525 909620..910222 1 NC_010278.1 DedA family integral membrane protein 910222 5852525 APJL_0827 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DedA family integral membrane protein YP_001651829.1 909620 D 434271 CDS YP_001651830.1 165976237 5852524 complement(910322..912754) 1 NC_010278.1 DNA gyrase subunit B 912754 gyrB 5852524 gyrB Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA gyrase subunit B YP_001651830.1 910322 R 434271 CDS YP_001651831.1 165976238 5852523 complement(912967..913848) 1 NC_010278.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 913848 ubiA 5852523 ubiA Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-hydroxybenzoate octaprenyltransferase YP_001651831.1 912967 R 434271 CDS YP_001651832.1 165976239 5852521 complement(913848..914609) 1 NC_010278.1 glycerol-3-phosphate regulon repressor 914609 glpR 5852521 glpR Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerol-3-phosphate regulon repressor YP_001651832.1 913848 R 434271 CDS YP_001651833.1 165976240 5852518 complement(914677..916044) 1 NC_010278.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 916044 purB 5852518 purB Actinobacillus pleuropneumoniae serovar 3 str. JL03 adenylosuccinate lyase YP_001651833.1 914677 R 434271 CDS YP_001651834.1 165976241 5852517 complement(916101..916733) 1 NC_010278.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 916733 5852517 APJL_0832 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651834.1 916101 R 434271 CDS YP_001651835.1 165976242 5852516 complement(916898..918565) 1 NC_010278.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 918565 cydC 5852516 cydC Actinobacillus pleuropneumoniae serovar 3 str. JL03 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001651835.1 916898 R 434271 CDS YP_001651836.1 165976243 5852515 complement(918576..920249) 1 NC_010278.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 920249 cydD 5852515 cydD Actinobacillus pleuropneumoniae serovar 3 str. JL03 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001651836.1 918576 R 434271 CDS YP_001651837.1 165976244 5852514 complement(920336..920503) 1 NC_010278.1 hypothetical protein 920503 5852514 APJL_0835 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651837.1 920336 R 434271 CDS YP_001651838.1 165976245 5852512 complement(920478..924437) 1 NC_010278.1 hypothetical protein 924437 5852512 APJL_0836 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651838.1 920478 R 434271 CDS YP_001651839.1 165976246 5852510 complement(924498..926324) 1 NC_010278.1 putative outer membrane protein 926324 5852510 APJL_0837 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative outer membrane protein YP_001651839.1 924498 R 434271 CDS YP_001651840.1 165976247 5852509 complement(926340..927020) 1 NC_010278.1 hypothetical protein 927020 5852509 APJL_0838 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651840.1 926340 R 434271 CDS YP_001651841.1 165976248 5852508 complement(927188..928387) 1 NC_010278.1 membrane-bound metallopeptidase 928387 5852508 APJL_0839 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane-bound metallopeptidase YP_001651841.1 927188 R 434271 CDS YP_001651842.1 165976249 5852505 928566..929249 1 NC_010278.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 929249 gpmA 5852505 gpmA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoglyceromutase YP_001651842.1 928566 D 434271 CDS YP_001651843.1 165976250 5852503 complement(929333..930064) 1 NC_010278.1 lysine efflux permease 930064 5852503 APJL_0841 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lysine efflux permease YP_001651843.1 929333 R 434271 CDS YP_001651844.1 165976251 5852501 930086..930739 1 NC_010278.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 930739 udk 5852501 udk Actinobacillus pleuropneumoniae serovar 3 str. JL03 uridine kinase YP_001651844.1 930086 D 434271 CDS YP_001651845.1 165976252 5852500 930748..931332 1 NC_010278.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 931332 dcd 5852500 dcd Actinobacillus pleuropneumoniae serovar 3 str. JL03 deoxycytidine triphosphate deaminase YP_001651845.1 930748 D 434271 CDS YP_001651846.1 165976253 5852499 complement(931401..931955) 1 NC_010278.1 transcriptional regulator 931955 5852499 APJL_0844 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001651846.1 931401 R 434271 CDS YP_001651847.1 165976254 5852498 932096..933157 1 NC_010278.1 membrane-fusion protein 933157 acrA2 5852498 acrA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane-fusion protein YP_001651847.1 932096 D 434271 CDS YP_001651848.1 165976255 5852496 933161..935902 1 NC_010278.1 multidrug ABC transporter ATPase 935902 ccmA1 5852496 ccmA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 multidrug ABC transporter ATPase YP_001651848.1 933161 D 434271 CDS YP_001651849.1 165976256 5852126 935904..937028 1 NC_010278.1 multidrug ABC transporter permease 937028 5852126 APJL_0847 Actinobacillus pleuropneumoniae serovar 3 str. JL03 multidrug ABC transporter permease YP_001651849.1 935904 D 434271 CDS YP_001651850.1 165976257 5852494 937045..938439 1 NC_010278.1 outer membrane protein 938439 tolC 5852494 tolC Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein YP_001651850.1 937045 D 434271 CDS YP_001651851.1 165976258 5852493 complement(938517..939965) 1 NC_010278.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 939965 pntB 5852493 pntB Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyridine nucleotide transhydrogenase YP_001651851.1 938517 R 434271 CDS YP_001651852.1 165976259 5852492 complement(939976..941514) 1 NC_010278.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 941514 pntA 5852492 pntA Actinobacillus pleuropneumoniae serovar 3 str. JL03 NAD(P) transhydrogenase subunit alpha YP_001651852.1 939976 R 434271 CDS YP_001651853.1 165976260 5852491 941719..942447 1 NC_010278.1 tRNA/rRNA methyltransferase 942447 5852491 APJL_0851 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA/rRNA methyltransferase YP_001651853.1 941719 D 434271 CDS YP_001651854.1 165976261 5852490 complement(942540..943631) 1 NC_010278.1 hypothetical protein 943631 5852490 APJL_0852 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651854.1 942540 R 434271 CDS YP_001651855.1 165976262 5852488 complement(943700..944791) 1 NC_010278.1 hypothetical protein 944791 5852488 APJL_0853 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651855.1 943700 R 434271 CDS YP_001651856.1 165976263 5852486 complement(945004..945843) 1 NC_010278.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 945843 queF 5852486 queF Actinobacillus pleuropneumoniae serovar 3 str. JL03 7-cyano-7-deazaguanine reductase YP_001651856.1 945004 R 434271 CDS YP_001651857.1 165976264 5852485 complement(945933..946481) 1 NC_010278.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 946481 5852485 APJL_0855 Actinobacillus pleuropneumoniae serovar 3 str. JL03 D,D-heptose 1,7-bisphosphate phosphatase YP_001651857.1 945933 R 434271 CDS YP_001651858.1 165976265 5852484 complement(946481..946951) 1 NC_010278.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 946951 bcp 5852484 bcp Actinobacillus pleuropneumoniae serovar 3 str. JL03 thioredoxin-dependent thiol peroxidase YP_001651858.1 946481 R 434271 CDS YP_001651859.1 165976266 5852482 complement(947016..947225) 1 NC_010278.1 hypothetical protein 947225 5852482 APJL_0857 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651859.1 947016 R 434271 CDS YP_001651860.1 165976267 5852481 complement(947338..948495) 1 NC_010278.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 948495 5852481 APJL_0858 Actinobacillus pleuropneumoniae serovar 3 str. JL03 coproporphyrinogen III oxidase YP_001651860.1 947338 R 434271 CDS YP_001651861.1 165976268 5852480 948758..950332 1 NC_010278.1 putative ABC transporter periplasmic binding protein 950332 5852480 APJL_0859 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative ABC transporter periplasmic binding protein YP_001651861.1 948758 D 434271 CDS YP_001651862.1 165976269 5852479 950431..951384 1 NC_010278.1 ABC transporter permease 951384 5852479 APJL_0860 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter permease YP_001651862.1 950431 D 434271 CDS YP_001651863.1 165976270 5852478 951384..953357 1 NC_010278.1 ABC transporter ATP-binding protein/permease 953357 5852478 APJL_0861 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein/permease YP_001651863.1 951384 D 434271 CDS YP_001651864.1 165976271 5852476 953361..954167 1 NC_010278.1 ABC transporter ATP-binding protein 954167 5852476 APJL_0862 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001651864.1 953361 D 434271 CDS YP_001651865.1 165976272 5852475 954217..955815 1 NC_010278.1 succinate dehydrogenase/fumarate reductase,flavoprotein subunit 955815 sdhA 5852475 sdhA Actinobacillus pleuropneumoniae serovar 3 str. JL03 succinate dehydrogenase/fumarate reductase,flavoprotein subunit YP_001651865.1 954217 D 434271 CDS YP_001651866.1 165976273 5852473 complement(955877..957025) 1 NC_010278.1 methionine synthase II 957025 5852473 APJL_0864 Actinobacillus pleuropneumoniae serovar 3 str. JL03 methionine synthase II YP_001651866.1 955877 R 434271 CDS YP_001651867.1 165976274 5852472 957254..958135 1 NC_010278.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 958135 metF 5852472 metF Actinobacillus pleuropneumoniae serovar 3 str. JL03 5,10-methylenetetrahydrofolate reductase YP_001651867.1 957254 D 434271 CDS YP_001651868.1 165976275 5852470 complement(958414..960006) 1 NC_010278.1 heme-binding protein A 960006 hbpA1 5852470 hbpA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 heme-binding protein A YP_001651868.1 958414 R 434271 CDS YP_001651869.1 165976276 5852468 960363..961592 1 NC_010278.1 serine transporter 961592 sdaC 5852468 sdaC Actinobacillus pleuropneumoniae serovar 3 str. JL03 serine transporter YP_001651869.1 960363 D 434271 CDS YP_001651870.1 165976277 5852467 961688..963067 1 NC_010278.1 L-serine dehydratase 963067 sdaA 5852467 sdaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-serine dehydratase YP_001651870.1 961688 D 434271 CDS YP_001651871.1 165976278 5852466 complement(963246..965261) 1 NC_010278.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 965261 mnmC 5852466 mnmC Actinobacillus pleuropneumoniae serovar 3 str. JL03 5-methylaminomethyl-2-thiouridine methyltransferase YP_001651871.1 963246 R 434271 CDS YP_001651872.1 165976279 5852464 complement(965465..966874) 1 NC_010278.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 966874 trpCF 5852464 trpCF Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_001651872.1 965465 R 434271 CDS YP_001651873.1 165976280 5852462 967052..967717 1 NC_010278.1 filamentation induced by cAMP protein Fic-like protein 967717 5852462 APJL_0871 Actinobacillus pleuropneumoniae serovar 3 str. JL03 filamentation induced by cAMP protein Fic-like protein YP_001651873.1 967052 D 434271 CDS YP_001651874.1 165976281 5852461 967725..968036 1 NC_010278.1 hypothetical protein 968036 5852461 APJL_0872 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651874.1 967725 D 434271 CDS YP_001651875.1 165976282 5852460 968037..968780 1 NC_010278.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 968780 5852460 APJL_0873 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA pseudouridine synthase C YP_001651875.1 968037 D 434271 CDS YP_001651876.1 165976283 5852459 968782..968946 1 NC_010278.1 hypothetical protein 968946 5852459 APJL_0874 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651876.1 968782 D 434271 CDS YP_001651877.1 165976284 5852458 968943..969395 1 NC_010278.1 hypothetical protein 969395 5852458 APJL_0875 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651877.1 968943 D 434271 CDS YP_001651878.1 165976285 5852457 complement(969439..970278) 1 NC_010278.1 hypothetical protein 970278 5852457 APJL_0876 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651878.1 969439 R 434271 CDS YP_001651879.1 165976286 5852456 970382..971755 1 NC_010278.1 hypothetical protein 971755 5852456 APJL_0877 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651879.1 970382 D 434271 CDS YP_001651880.1 165976287 5852455 971810..971935 1 NC_010278.1 hypothetical protein 971935 5852455 APJL_0878 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651880.1 971810 D 434271 CDS YP_001651881.1 165976288 5852454 971928..972368 1 NC_010278.1 SsrA-binding protein, small major protein B 972368 smpB 5852454 smpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 SsrA-binding protein, small major protein B YP_001651881.1 971928 D 434271 CDS YP_001651882.1 165976289 5852453 972486..973793 1 NC_010278.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 973793 serS 5852453 serS Actinobacillus pleuropneumoniae serovar 3 str. JL03 seryl-tRNA synthetase YP_001651882.1 972486 D 434271 CDS YP_001651883.1 165976290 5852452 complement(973864..975132) 1 NC_010278.1 aminobenzoyl-glutamate utilization protein 975132 5852452 APJL_0881 Actinobacillus pleuropneumoniae serovar 3 str. JL03 aminobenzoyl-glutamate utilization protein YP_001651883.1 973864 R 434271 CDS YP_001651884.1 165976291 5852450 complement(975226..976518) 1 NC_010278.1 C4-dicarboxylate transporter 976518 5852450 APJL_0882 Actinobacillus pleuropneumoniae serovar 3 str. JL03 C4-dicarboxylate transporter YP_001651884.1 975226 R 434271 CDS YP_001651885.1 165976292 5852449 complement(976529..977233) 1 NC_010278.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 977233 pepE 5852449 pepE Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptidase E YP_001651885.1 976529 R 434271 CDS YP_001651886.1 165976293 5852448 977484..980069 1 NC_010278.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 980069 leuS 5852448 leuS Actinobacillus pleuropneumoniae serovar 3 str. JL03 leucyl-tRNA synthetase YP_001651886.1 977484 D 434271 CDS YP_001651887.1 165976294 5852447 980169..980663 1 NC_010278.1 rare lipoprotein B 980663 rlpB 5852447 rlpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 rare lipoprotein B YP_001651887.1 980169 D 434271 CDS YP_001651888.1 165976295 5852446 980772..981797 1 NC_010278.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 981797 holA 5852446 holA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunit delta YP_001651888.1 980772 D 434271 CDS YP_001651889.1 165976296 5852445 complement(981874..982062) 1 NC_010278.1 zinc-binding protein 982062 yacG 5852445 yacG Actinobacillus pleuropneumoniae serovar 3 str. JL03 zinc-binding protein YP_001651889.1 981874 R 434271 CDS YP_001651890.1 165976297 5852444 complement(982044..982682) 1 NC_010278.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 982682 coaE 5852444 coaE Actinobacillus pleuropneumoniae serovar 3 str. JL03 dephospho-CoA kinase YP_001651890.1 982044 R 434271 CDS YP_001651891.1 165976298 5852443 complement(982704..983342) 1 NC_010278.1 leader peptidase HopD 983342 hopD 5852443 hopD Actinobacillus pleuropneumoniae serovar 3 str. JL03 leader peptidase HopD YP_001651891.1 982704 R 434271 CDS YP_001651892.1 165976299 5852442 complement(983369..984571) 1 NC_010278.1 protein transport protein HofC-like protein 984571 hofC 5852442 hofC Actinobacillus pleuropneumoniae serovar 3 str. JL03 protein transport protein HofC-like protein YP_001651892.1 983369 R 434271 CDS YP_001651893.1 165976300 5852440 complement(984555..985949) 1 NC_010278.1 protein transport protein HofB-like protein, pili/fimbriae biogenesis protein 985949 hofB 5852440 hofB Actinobacillus pleuropneumoniae serovar 3 str. JL03 protein transport protein HofB-like protein, pili/fimbriae biogenesis protein YP_001651893.1 984555 R 434271 CDS YP_001651894.1 165976301 5852439 complement(985967..986413) 1 NC_010278.1 prepilin peptidase dependent protein D 986413 apfA 5852439 apfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 prepilin peptidase dependent protein D YP_001651894.1 985967 R 434271 CDS YP_001651895.1 165976302 5852438 986595..987974 1 NC_010278.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 987974 radA 5852438 radA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA repair protein RadA YP_001651895.1 986595 D 434271 CDS YP_001651896.1 165976303 5852437 complement(988018..988251) 1 NC_010278.1 hypothetical protein 988251 5852437 APJL_0894 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651896.1 988018 R 434271 CDS YP_001651897.1 165976304 5852436 complement(988378..988866) 1 NC_010278.1 dihydrofolate reductase 988866 folA 5852436 folA Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydrofolate reductase YP_001651897.1 988378 R 434271 CDS YP_001651898.1 165976305 5852435 988953..990044 1 NC_010278.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 990044 proB 5852435 proB Actinobacillus pleuropneumoniae serovar 3 str. JL03 gamma-glutamyl kinase YP_001651898.1 988953 D 434271 CDS YP_001651899.1 165976306 5852433 990057..990833 1 NC_010278.1 permease 990833 5852433 APJL_0897 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001651899.1 990057 D 434271 CDS YP_001651900.1 165976307 5852430 990834..991433 1 NC_010278.1 endonuclease III 991433 nth 5852430 nth Actinobacillus pleuropneumoniae serovar 3 str. JL03 endonuclease III YP_001651900.1 990834 D 434271 CDS YP_001651901.1 165976308 5852429 991677..992981 1 NC_010278.1 acetyl-CoA acetyltransferase 992981 fadI 5852429 fadI Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyl-CoA acetyltransferase YP_001651901.1 991677 D 434271 CDS YP_001651902.1 165976309 5852428 992991..995108 1 NC_010278.1 fatty oxidation complex subunit alpha 995108 fadJ 5852428 fadJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 fatty oxidation complex subunit alpha YP_001651902.1 992991 D 434271 CDS YP_001651903.1 165976310 5852427 995199..996614 1 NC_010278.1 hypothetical protein 996614 5852427 APJL_0901 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651903.1 995199 D 434271 CDS YP_001651904.1 165976311 5852424 complement(996697..997629) 1 NC_010278.1 permease 997629 5852424 APJL_0902 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001651904.1 996697 R 434271 CDS YP_001651905.1 165976312 5852423 complement(997631..998437) 1 NC_010278.1 formate dehydrogenase formation protein 998437 fdhD 5852423 fdhD Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate dehydrogenase formation protein YP_001651905.1 997631 R 434271 CDS YP_001651906.1 165976313 5852422 998857..999444 1 NC_010278.1 formate dehydrogenase subunit alpha 999444 bisC1 5852422 bisC1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate dehydrogenase subunit alpha YP_001651906.1 998857 D 434271 CDS YP_001651907.1 165976314 5852421 999493..1001916 1 NC_010278.1 formate dehydrogenase subunit alpha 1001916 bisC2 5852421 bisC2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate dehydrogenase subunit alpha YP_001651907.1 999493 D 434271 CDS YP_001651908.1 165976315 5852420 1001916..1002815 1 NC_010278.1 formate dehydrogenase subunit beta 1002815 hybA1 5852420 hybA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate dehydrogenase subunit beta YP_001651908.1 1001916 D 434271 CDS YP_001651909.1 165976316 5852419 1002808..1003479 1 NC_010278.1 formate dehydrogenase subunit gamma 1003479 fdnI 5852419 fdnI Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate dehydrogenase subunit gamma YP_001651909.1 1002808 D 434271 CDS YP_001651910.1 165976317 5852418 1003589..1004506 1 NC_010278.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 1004506 fdhE 5852418 fdhE Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate dehydrogenase accessory protein FdhE YP_001651910.1 1003589 D 434271 CDS YP_001651911.1 165976318 5852414 1005109..1005966 1 NC_010278.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1005966 folD 5852414 folD Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001651911.1 1005109 D 434271 CDS YP_001651912.1 165976319 5852412 1006111..1007649 1 NC_010278.1 putative oxalate/formate antiporter 1007649 5852412 APJL_0910 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative oxalate/formate antiporter YP_001651912.1 1006111 D 434271 CDS YP_001651913.1 165976320 5852411 complement(1007747..1008634) 1 NC_010278.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1008634 dapA 5852411 dapA Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydrodipicolinate synthase YP_001651913.1 1007747 R 434271 CDS YP_001651914.1 165976321 5852410 complement(1008793..1009734) 1 NC_010278.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1009734 lpxL 5852410 lpxL Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipid A biosynthesis lauroyl acyltransferase YP_001651914.1 1008793 R 434271 CDS YP_001651915.1 165976322 5852408 1009899..1010213 1 NC_010278.1 putative sigma 54 modulation protein 1010213 5852408 APJL_0913 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sigma 54 modulation protein YP_001651915.1 1009899 D 434271 CDS YP_001651916.1 165976323 5852407 complement(1010271..1011059) 1 NC_010278.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1011059 truA 5852407 truA Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA pseudouridine synthase A YP_001651916.1 1010271 R 434271 CDS YP_001651917.1 165976324 5852406 complement(1011138..1011794) 1 NC_010278.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1011794 folE 5852406 folE Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTP cyclohydrolase I YP_001651917.1 1011138 R 434271 CDS YP_001651918.1 165976325 5852405 1011895..1012599 1 NC_010278.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase 1012599 kdkA 5852405 kdkA Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-deoxy-D-manno-octulosonic-acid kinase YP_001651918.1 1011895 D 434271 CDS YP_001651919.1 165976326 5852404 complement(1012679..1013017) 1 NC_010278.1 hypothetical protein 1013017 5852404 APJL_0917 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651919.1 1012679 R 434271 CDS YP_001651920.1 165976327 5852403 complement(1013076..1013651) 1 NC_010278.1 acetyltransferase 1013651 wbbJ 5852403 wbbJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyltransferase YP_001651920.1 1013076 R 434271 CDS YP_001651921.1 165976328 5852712 complement(1013735..1014877) 1 NC_010278.1 alpha/beta fold family hydrolase 1014877 5852712 APJL_0919 Actinobacillus pleuropneumoniae serovar 3 str. JL03 alpha/beta fold family hydrolase YP_001651921.1 1013735 R 434271 CDS YP_001651922.1 165976329 5852402 1015036..1015920 1 NC_010278.1 putative transcriptional regulator 1015920 5852402 APJL_0920 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transcriptional regulator YP_001651922.1 1015036 D 434271 CDS YP_001651923.1 165976330 5852400 complement(1015973..1016791) 1 NC_010278.1 outer membrane lipoprotein 2 1016791 plpB 5852400 plpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane lipoprotein 2 YP_001651923.1 1015973 R 434271 CDS YP_001651924.1 165976331 5852399 complement(1016905..1017726) 1 NC_010278.1 outer membrane lipoprotein 1017726 hlpA 5852399 hlpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane lipoprotein YP_001651924.1 1016905 R 434271 CDS YP_001651925.1 165976332 5852398 complement(1017752..1018429) 1 NC_010278.1 ABC transporter permease 1018429 5852398 APJL_0923 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter permease YP_001651925.1 1017752 R 434271 CDS YP_001651926.1 165976333 5852397 complement(1018419..1019453) 1 NC_010278.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 1019453 metN 5852397 metN Actinobacillus pleuropneumoniae serovar 3 str. JL03 DL-methionine transporter ATP-binding subunit YP_001651926.1 1018419 R 434271 CDS YP_001651927.1 165976334 5852396 complement(1019651..1021030) 1 NC_010278.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1021030 cysS 5852396 cysS Actinobacillus pleuropneumoniae serovar 3 str. JL03 cysteinyl-tRNA synthetase YP_001651927.1 1019651 R 434271 CDS YP_001651928.1 165976335 5852395 1021175..1021684 1 NC_010278.1 peptidyl-prolyl cis-trans isomerase B 1021684 ppiB 5852395 ppiB Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptidyl-prolyl cis-trans isomerase B YP_001651928.1 1021175 D 434271 CDS YP_001651929.1 165976336 5852393 1021713..1022951 1 NC_010278.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 1022951 cca 5852393 cca Actinobacillus pleuropneumoniae serovar 3 str. JL03 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_001651929.1 1021713 D 434271 CDS YP_001651930.1 165976337 5852392 1023096..1023605 1 NC_010278.1 transposase and inactivated derivative 1023605 5852392 APJL_0928 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001651930.1 1023096 D 434271 CDS YP_001651931.1 165976338 5852391 1023617..1024429 1 NC_010278.1 transposase 1024429 5852391 APJL_0929 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001651931.1 1023617 D 434271 CDS YP_001651932.1 165976339 5852390 complement(1024475..1026847) 1 NC_010278.1 iron-regulated outer membrane protein 1026847 irp 5852390 irp Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-regulated outer membrane protein YP_001651932.1 1024475 R 434271 CDS YP_001651933.1 165976340 5852389 1027009..1028265 1 NC_010278.1 hypothetical protein 1028265 5852389 APJL_0931 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651933.1 1027009 D 434271 CDS YP_001651934.1 165976341 5852388 1028321..1029736 1 NC_010278.1 hypothetical protein 1029736 5852388 APJL_0932 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651934.1 1028321 D 434271 CDS YP_001651935.1 165976342 5852387 complement(1030762..1030956) 1 NC_010278.1 hypothetical protein 1030956 5852387 APJL_0933 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651935.1 1030762 R 434271 CDS YP_001651936.1 165976343 5852386 complement(1030956..1031297) 1 NC_010278.1 ferredoxin 1031297 fdx2 5852386 fdx2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferredoxin YP_001651936.1 1030956 R 434271 CDS YP_001651937.1 165976344 5852384 complement(1031418..1033271) 1 NC_010278.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 1033271 hscA 5852384 hscA Actinobacillus pleuropneumoniae serovar 3 str. JL03 chaperone protein HscA YP_001651937.1 1031418 R 434271 CDS YP_001651938.1 165976345 5852383 complement(1033390..1034022) 1 NC_010278.1 hypothetical protein 1034022 5852383 APJL_0936 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651938.1 1033390 R 434271 CDS YP_001651939.1 165976346 5852381 complement(1034050..1034502) 1 NC_010278.1 hypothetical protein 1034502 5852381 APJL_0937 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651939.1 1034050 R 434271 CDS YP_001651940.1 165976347 5852380 complement(1034550..1035071) 1 NC_010278.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 1035071 hscB 5852380 hscB Actinobacillus pleuropneumoniae serovar 3 str. JL03 co-chaperone HscB YP_001651940.1 1034550 R 434271 CDS YP_001651941.1 165976348 5852379 complement(1035081..1035404) 1 NC_010278.1 iron-binding protein 1035404 iscA 5852379 iscA Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-binding protein YP_001651941.1 1035081 R 434271 CDS YP_001651942.1 165976349 5852378 complement(1035546..1035929) 1 NC_010278.1 scaffold protein 1035929 iscU 5852378 iscU Actinobacillus pleuropneumoniae serovar 3 str. JL03 scaffold protein YP_001651942.1 1035546 R 434271 CDS YP_001651943.1 165976350 5852377 complement(1036063..1037289) 1 NC_010278.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 1037289 iscS 5852377 iscS Actinobacillus pleuropneumoniae serovar 3 str. JL03 cysteine desulfurase YP_001651943.1 1036063 R 434271 CDS YP_001651944.1 165976351 5852376 complement(1037344..1037796) 1 NC_010278.1 putative HTH-type transcriptional regulator 1037796 5852376 APJL_0942 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative HTH-type transcriptional regulator YP_001651944.1 1037344 R 434271 CDS YP_001651945.1 165976352 5852375 1038286..1039677 1 NC_010278.1 outer membrane protein P1 1039677 ompP1 5852375 ompP1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein P1 YP_001651945.1 1038286 D 434271 CDS YP_001651946.1 165976353 5852373 1039763..1040326 1 NC_010278.1 methylated-DNA--protein-cysteine S-methyltransferase 1040326 ogt 5852373 ogt Actinobacillus pleuropneumoniae serovar 3 str. JL03 methylated-DNA--protein-cysteine S-methyltransferase YP_001651946.1 1039763 D 434271 CDS YP_001651947.1 165976354 5852372 complement(1040346..1042196) 1 NC_010278.1 sensor histidine kinase 1042196 arcB 5852372 arcB Actinobacillus pleuropneumoniae serovar 3 str. JL03 sensor histidine kinase YP_001651947.1 1040346 R 434271 CDS YP_001651948.1 165976355 5852370 complement(1042302..1043165) 1 NC_010278.1 putative integral membrane protein 1043165 5852370 APJL_0946 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative integral membrane protein YP_001651948.1 1042302 R 434271 CDS YP_001651949.1 165976356 5852369 complement(1043281..1043823) 1 NC_010278.1 hypothetical protein 1043823 5852369 APJL_0947 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651949.1 1043281 R 434271 CDS YP_001651950.1 165976357 5852368 complement(1043813..1044457) 1 NC_010278.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1044457 bioD 5852368 bioD Actinobacillus pleuropneumoniae serovar 3 str. JL03 dithiobiotin synthetase YP_001651950.1 1043813 R 434271 CDS YP_001651951.1 165976358 5852367 complement(1044457..1045227) 1 NC_010278.1 biotin synthesis protein 1045227 bioC 5852367 bioC Actinobacillus pleuropneumoniae serovar 3 str. JL03 biotin synthesis protein YP_001651951.1 1044457 R 434271 CDS YP_001651952.1 165976359 5852366 complement(1045215..1045874) 1 NC_010278.1 hypothetical protein 1045874 5852366 APJL_0950 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651952.1 1045215 R 434271 CDS YP_001651953.1 165976360 5852365 complement(1045884..1047047) 1 NC_010278.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1047047 bioF 5852365 bioF Actinobacillus pleuropneumoniae serovar 3 str. JL03 8-amino-7-oxononanoate synthase YP_001651953.1 1045884 R 434271 CDS YP_001651954.1 165976361 5852363 complement(1047074..1048372) 1 NC_010278.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1048372 bioA 5852363 bioA Actinobacillus pleuropneumoniae serovar 3 str. JL03 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001651954.1 1047074 R 434271 CDS YP_001651955.1 165976362 5852361 1048463..1049407 1 NC_010278.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1049407 5852361 APJL_0953 Actinobacillus pleuropneumoniae serovar 3 str. JL03 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001651955.1 1048463 D 434271 CDS YP_001651956.1 165976363 5852360 complement(1049489..1049965) 1 NC_010278.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1049965 greA 5852360 greA Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcription elongation factor GreA YP_001651956.1 1049489 R 434271 CDS YP_001651957.1 165976364 5852359 1050049..1051491 1 NC_010278.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1051491 dacB 5852359 dacB Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-alanyl-D-alanine carboxypeptidase YP_001651957.1 1050049 D 434271 CDS YP_001651958.1 165976365 5852357 complement(1051528..1051797) 1 NC_010278.1 acetyltransferase 1051797 5852357 APJL_0956 Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyltransferase YP_001651958.1 1051528 R 434271 CDS YP_001651959.1 165976366 5852354 complement(1052116..1053237) 1 NC_010278.1 hypothetical protein 1053237 5852354 APJL_0957 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651959.1 1052116 R 434271 CDS YP_001651960.1 165976367 5852353 complement(1053649..1053996) 1 NC_010278.1 hypothetical protein 1053996 5852353 APJL_0958 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651960.1 1053649 R 434271 CDS YP_001651961.1 165976368 5852352 1054068..1055108 1 NC_010278.1 hypothetical protein 1055108 5852352 APJL_0959 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651961.1 1054068 D 434271 CDS YP_001651962.1 165976369 5852351 complement(1055147..1056181) 1 NC_010278.1 hypothetical protein 1056181 5852351 APJL_0960 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651962.1 1055147 R 434271 CDS YP_001651963.1 165976370 5852349 complement(1056174..1056737) 1 NC_010278.1 Zn peptidase 1056737 5852349 APJL_0961 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Zn peptidase YP_001651963.1 1056174 R 434271 CDS YP_001651964.1 165976371 5852348 complement(1056891..1057199) 1 NC_010278.1 hypothetical protein 1057199 5852348 APJL_0962 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651964.1 1056891 R 434271 CDS YP_001651965.1 165976372 5852347 1057262..1058347 1 NC_010278.1 putative transposase 1058347 5852347 APJL_0963 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transposase YP_001651965.1 1057262 D 434271 CDS YP_001651966.1 165976373 5852346 1058347..1058781 1 NC_010278.1 DNA repair ATPase 1058781 5852346 APJL_0964 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA repair ATPase YP_001651966.1 1058347 D 434271 CDS YP_001651967.1 165976374 5852345 complement(1058782..1059171) 1 NC_010278.1 hypothetical protein 1059171 5852345 APJL_0965 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651967.1 1058782 R 434271 CDS YP_001651968.1 165976375 5852344 complement(1059213..1059785) 1 NC_010278.1 leukotoxin translocation ATP-binding protein 1059785 apxIIB 5852344 apxIIB Actinobacillus pleuropneumoniae serovar 3 str. JL03 leukotoxin translocation ATP-binding protein YP_001651968.1 1059213 R 434271 CDS YP_001651969.1 165976376 5852343 complement(1059850..1062720) 1 NC_010278.1 hemolysin A 1062720 apxIIA 5852343 apxIIA Actinobacillus pleuropneumoniae serovar 3 str. JL03 hemolysin A YP_001651969.1 1059850 R 434271 CDS YP_001651970.1 165976377 5852342 complement(1062759..1063241) 1 NC_010278.1 hemolysin-activating lysine-acyltransferase HlyC 1063241 apxIIC 5852342 apxIIC Actinobacillus pleuropneumoniae serovar 3 str. JL03 hemolysin-activating lysine-acyltransferase HlyC YP_001651970.1 1062759 R 434271 CDS YP_001651971.1 165976378 5852340 complement(1063418..1065286) 1 NC_010278.1 hypothetical protein 1065286 5852340 APJL_0969 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651971.1 1063418 R 434271 CDS YP_001651972.1 165976379 5852338 complement(1065316..1065807) 1 NC_010278.1 putative metalloprotease 1065807 5852338 APJL_0970 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative metalloprotease YP_001651972.1 1065316 R 434271 CDS YP_001651973.1 165976380 5852336 1066230..1067819 1 NC_010278.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1067819 purH 5852336 purH Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001651973.1 1066230 D 434271 CDS YP_001651974.1 165976381 5852335 1067928..1068968 1 NC_010278.1 hypothetical protein 1068968 5852335 APJL_0972 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651974.1 1067928 D 434271 CDS YP_001651975.1 165976382 5852334 complement(1069217..1069573) 1 NC_010278.1 hypothetical protein 1069573 5852334 APJL_0973 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651975.1 1069217 R 434271 CDS YP_001651976.1 165976383 5852333 complement(1069587..1069892) 1 NC_010278.1 hypothetical protein 1069892 5852333 APJL_0974 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651976.1 1069587 R 434271 CDS YP_001651977.1 165976384 5852331 complement(1069984..1070148) 1 NC_010278.1 hypothetical protein 1070148 5852331 APJL_0975 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651977.1 1069984 R 434271 CDS YP_001651978.1 165976385 5852330 complement(1070293..1070625) 1 NC_010278.1 hypothetical protein 1070625 5852330 APJL_0976 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651978.1 1070293 R 434271 CDS YP_001651979.1 165976386 5852329 complement(1070622..1070834) 1 NC_010278.1 heme utilization or adhesion protein 1070834 5852329 APJL_0977 Actinobacillus pleuropneumoniae serovar 3 str. JL03 heme utilization or adhesion protein YP_001651979.1 1070622 R 434271 CDS YP_001651980.1 165976387 5852327 complement(1071004..1071303) 1 NC_010278.1 hypothetical protein 1071303 5852327 APJL_0978 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651980.1 1071004 R 434271 CDS YP_001651981.1 165976388 5852326 complement(1071300..1079093) 1 NC_010278.1 heme utilization or adhesion protein 1079093 5852326 APJL_0979 Actinobacillus pleuropneumoniae serovar 3 str. JL03 heme utilization or adhesion protein YP_001651981.1 1071300 R 434271 CDS YP_001651982.1 165976389 5852324 complement(1079141..1080913) 1 NC_010278.1 hemolysin activation/secretion protein 1080913 5852324 APJL_0980 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hemolysin activation/secretion protein YP_001651982.1 1079141 R 434271 CDS YP_001651983.1 165976390 5852323 complement(1081096..1083432) 1 NC_010278.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 1083432 imp 5852323 imp Actinobacillus pleuropneumoniae serovar 3 str. JL03 organic solvent tolerance protein YP_001651983.1 1081096 R 434271 CDS YP_001651984.1 165976391 5852322 complement(1083489..1084856) 1 NC_010278.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1084856 hemN 5852322 hemN Actinobacillus pleuropneumoniae serovar 3 str. JL03 coproporphyrinogen III oxidase YP_001651984.1 1083489 R 434271 CDS YP_001651985.1 165976392 5852321 complement(1084886..1085353) 1 NC_010278.1 putative coproporphyrinogen III oxidase 1085353 5852321 APJL_0983 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative coproporphyrinogen III oxidase YP_001651985.1 1084886 R 434271 CDS YP_001651986.1 165976393 5852320 complement(1085369..1085947) 1 NC_010278.1 hypothetical protein 1085947 5852320 APJL_0984 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651986.1 1085369 R 434271 CDS YP_001651987.1 165976394 5852318 complement(1086096..1087754) 1 NC_010278.1 hypothetical protein 1087754 5852318 APJL_0985 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651987.1 1086096 R 434271 CDS YP_001651988.1 165976395 5852315 1088017..1089234 1 NC_010278.1 sodium/glutamate symporter 1089234 gltS 5852315 gltS Actinobacillus pleuropneumoniae serovar 3 str. JL03 sodium/glutamate symporter YP_001651988.1 1088017 D 434271 CDS YP_001651989.1 165976396 5852314 complement(1089304..1089681) 1 NC_010278.1 hypothetical protein 1089681 5852314 APJL_0987 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651989.1 1089304 R 434271 CDS YP_001651990.1 165976397 5852313 complement(1089778..1092657) 1 NC_010278.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1092657 glnE 5852313 glnE Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_001651990.1 1089778 R 434271 CDS YP_001651991.1 165976398 5852312 complement(1092732..1093013) 1 NC_010278.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1093013 5852312 APJL_0989 Actinobacillus pleuropneumoniae serovar 3 str. JL03 YciI-like protein YP_001651991.1 1092732 R 434271 CDS YP_001651992.1 165976399 5852311 complement(1093024..1093515) 1 NC_010278.1 putative acyl CoA thioester hydrolase 1093515 5852311 APJL_0990 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative acyl CoA thioester hydrolase YP_001651992.1 1093024 R 434271 CDS YP_001651993.1 165976400 5852308 complement(1093502..1094053) 1 NC_010278.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1094053 ispZ 5852308 ispZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 intracellular septation protein A YP_001651993.1 1093502 R 434271 CDS YP_001651994.1 165976401 5852307 complement(1094055..1094792) 1 NC_010278.1 hypothetical protein 1094792 5852307 APJL_0992 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651994.1 1094055 R 434271 CDS YP_001651995.1 165976402 5852306 1094951..1095385 1 NC_010278.1 membrane protein 1095385 5852306 APJL_0993 Actinobacillus pleuropneumoniae serovar 3 str. JL03 membrane protein YP_001651995.1 1094951 D 434271 CDS YP_001651996.1 165976403 5852305 1095398..1095556 1 NC_010278.1 hypothetical protein 1095556 5852305 APJL_0994 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001651996.1 1095398 D 434271 CDS YP_001651997.1 165976404 5852304 1095553..1096509 1 NC_010278.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1096509 5852304 APJL_0995 Actinobacillus pleuropneumoniae serovar 3 str. JL03 C32 tRNA thiolase YP_001651997.1 1095553 D 434271 CDS YP_001651998.1 165976405 5852303 1096716..1098092 1 NC_010278.1 permease 1098092 5852303 APJL_0996 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001651998.1 1096716 D 434271 CDS YP_001651999.1 165976406 5852302 1098144..1098986 1 NC_010278.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1098986 xthA 5852302 xthA Actinobacillus pleuropneumoniae serovar 3 str. JL03 exonuclease III YP_001651999.1 1098144 D 434271 CDS YP_001652000.1 165976407 5852301 complement(1099050..1099934) 1 NC_010278.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 1099934 lysR1 5852301 lysR1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding transcriptional regulator IlvY YP_001652000.1 1099050 R 434271 CDS YP_001652001.1 165976408 5852300 complement(1099935..1100975) 1 NC_010278.1 putative D-glycero-D-manno-heptosyltransferase 1100975 5852300 APJL_0999 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative D-glycero-D-manno-heptosyltransferase YP_001652001.1 1099935 R 434271 CDS YP_001652002.1 165976409 5852299 complement(1100977..1101660) 1 NC_010278.1 lipooligosaccharide galactosyltransferase I 1101660 lbgA 5852299 lbgA Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipooligosaccharide galactosyltransferase I YP_001652002.1 1100977 R 434271 CDS YP_001652003.1 165976410 5852298 1101769..1102830 1 NC_010278.1 hypothetical protein 1102830 5852298 APJL_1001 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652003.1 1101769 D 434271 CDS YP_001652004.1 165976411 5852297 complement(1102892..1103104) 1 NC_010278.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1103104 rpmE 5852297 rpmE Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L31 YP_001652004.1 1102892 R 434271 CDS YP_001652005.1 165976412 5852295 1103486..1105492 1 NC_010278.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1105492 tktA 5852295 tktA Actinobacillus pleuropneumoniae serovar 3 str. JL03 transketolase YP_001652005.1 1103486 D 434271 CDS YP_001652006.1 165976413 5852294 complement(1105626..1107503) 1 NC_010278.1 molecular chaperone; heat shock protein 90 1107503 htpG 5852294 htpG Actinobacillus pleuropneumoniae serovar 3 str. JL03 heat shock protein 90 YP_001652006.1 1105626 R 434271 CDS YP_001652007.1 165976414 5852292 1107731..1109257 1 NC_010278.1 catalase 1109257 katA 5852292 katA Actinobacillus pleuropneumoniae serovar 3 str. JL03 catalase YP_001652007.1 1107731 D 434271 CDS YP_001652008.1 165976415 5852291 1109424..1109603 1 NC_010278.1 transposase and inactivated derivative 1109603 5852291 APJL_1006 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001652008.1 1109424 D 434271 CDS YP_001652009.1 165976416 5852290 1109623..1109961 1 NC_010278.1 transposase 1109961 5852290 APJL_1007 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001652009.1 1109623 D 434271 CDS YP_001652010.1 165976417 5852289 1110074..1111153 1 NC_010278.1 phosphohydrolase 1111153 5852289 APJL_1008 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphohydrolase YP_001652010.1 1110074 D 434271 CDS YP_001652011.1 165976418 5852288 1111367..1113637 1 NC_010278.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1113637 nrdA 5852288 nrdA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonucleotide-diphosphate reductase subunit alpha YP_001652011.1 1111367 D 434271 CDS YP_001652012.1 165976419 5852287 1113934..1115064 1 NC_010278.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1115064 nrdB 5852287 nrdB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonucleotide-diphosphate reductase subunit beta YP_001652012.1 1113934 D 434271 CDS YP_001652013.1 165976420 5852286 1115326..1116375 1 NC_010278.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 1116375 galT 5852286 galT Actinobacillus pleuropneumoniae serovar 3 str. JL03 galactose-1-phosphate uridylyltransferase YP_001652013.1 1115326 D 434271 CDS YP_001652014.1 165976421 5852285 1116403..1117557 1 NC_010278.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1117557 galK 5852285 galK Actinobacillus pleuropneumoniae serovar 3 str. JL03 galactokinase YP_001652014.1 1116403 D 434271 CDS YP_001652015.1 165976422 5852283 1117615..1118583 1 NC_010278.1 aldose 1-epimerase 1118583 galM 5852283 galM Actinobacillus pleuropneumoniae serovar 3 str. JL03 aldose 1-epimerase YP_001652015.1 1117615 D 434271 CDS YP_001652016.1 165976423 5852282 1118608..1121628 1 NC_010278.1 beta-galactosidase/beta-glucuronidase 1121628 lacZ 5852282 lacZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 beta-galactosidase/beta-glucuronidase YP_001652016.1 1118608 D 434271 CDS YP_001652017.1 165976424 5852279 complement(1126340..1126810) 1 NC_010278.1 hypothetical protein 1126810 5852279 APJL_1017 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652017.1 1126340 R 434271 CDS YP_001652018.1 165976425 5852278 complement(1127007..1128104) 1 NC_010278.1 putative ATPase 1128104 mrp 5852278 mrp Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative ATPase YP_001652018.1 1127007 R 434271 CDS YP_001652019.1 165976426 5852277 complement(1128108..1129658) 1 NC_010278.1 putative oligopeptide transporter,periplasmic-binding protein 1129658 5852277 APJL_1019 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative oligopeptide transporter,periplasmic-binding protein YP_001652019.1 1128108 R 434271 CDS YP_001652020.1 165976427 5852276 complement(1129673..1130326) 1 NC_010278.1 hypothetical protein 1130326 5852276 APJL_1020 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652020.1 1129673 R 434271 CDS YP_001652021.1 165976428 5852275 complement(1130448..1132325) 1 NC_010278.1 peptidyl-prolyl cis-trans isomerase D 1132325 ppiD 5852275 ppiD Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptidyl-prolyl cis-trans isomerase D YP_001652021.1 1130448 R 434271 CDS YP_001652022.1 165976429 5852274 1132554..1133867 1 NC_010278.1 Na+/H+ antiporter 1133867 nhaP 5852274 nhaP Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na+/H+ antiporter YP_001652022.1 1132554 D 434271 CDS YP_001652023.1 165976430 5852273 1133989..1134258 1 NC_010278.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1134258 rpsO 5852273 rpsO Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S15 YP_001652023.1 1133989 D 434271 CDS YP_001652024.1 165976431 5852272 1134336..1135205 1 NC_010278.1 inner membrane protein 1135205 5852272 APJL_1024 Actinobacillus pleuropneumoniae serovar 3 str. JL03 inner membrane protein YP_001652024.1 1134336 D 434271 CDS YP_001652025.1 165976432 5852270 complement(1135263..1136513) 1 NC_010278.1 HemY protein 1136513 hemY 5852270 hemY Actinobacillus pleuropneumoniae serovar 3 str. JL03 HemY protein YP_001652025.1 1135263 R 434271 CDS YP_001652026.1 165976433 5852269 complement(1136525..1137865) 1 NC_010278.1 putative uroporphyrinogen IIIC-methyltransferase 1137865 hemX 5852269 hemX Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative uroporphyrinogen IIIC-methyltransferase YP_001652026.1 1136525 R 434271 CDS YP_001652027.1 165976434 5852268 complement(1137875..1138588) 1 NC_010278.1 uroporphyrinogen-III synthase 1138588 hemD 5852268 hemD Actinobacillus pleuropneumoniae serovar 3 str. JL03 uroporphyrinogen-III synthase YP_001652027.1 1137875 R 434271 CDS YP_001652028.1 165976435 5852267 complement(1138648..1139592) 1 NC_010278.1 porphobilinogen deaminase 1139592 hemC 5852267 hemC Actinobacillus pleuropneumoniae serovar 3 str. JL03 porphobilinogen deaminase YP_001652028.1 1138648 R 434271 CDS YP_001652029.1 165976436 5852266 1139846..1142461 1 NC_010278.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1142461 adh2 5852266 adh2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_001652029.1 1139846 D 434271 CDS YP_001652030.1 165976437 5852265 complement(1142635..1144278) 1 NC_010278.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1144278 groEL 5852265 groEL Actinobacillus pleuropneumoniae serovar 3 str. JL03 chaperonin GroEL YP_001652030.1 1142635 R 434271 CDS YP_001652031.1 165976438 5852263 complement(1144338..1144628) 1 NC_010278.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1144628 groES 5852263 groES Actinobacillus pleuropneumoniae serovar 3 str. JL03 co-chaperonin GroES YP_001652031.1 1144338 R 434271 CDS YP_001652032.1 165976439 5852262 complement(1144840..1145562) 1 NC_010278.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 1145562 deoD 5852262 deoD Actinobacillus pleuropneumoniae serovar 3 str. JL03 purine nucleoside phosphorylase YP_001652032.1 1144840 R 434271 CDS YP_001652033.1 165976440 5852260 complement(1145621..1146397) 1 NC_010278.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1146397 deoC 5852260 deoC Actinobacillus pleuropneumoniae serovar 3 str. JL03 deoxyribose-phosphate aldolase YP_001652033.1 1145621 R 434271 CDS YP_001652034.1 165976441 5852259 complement(1146534..1147802) 1 NC_010278.1 nucleoside permease 1147802 5852259 APJL_1034 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nucleoside permease YP_001652034.1 1146534 R 434271 CDS YP_001652035.1 165976442 5852258 1148016..1148660 1 NC_010278.1 hypothetical protein 1148660 5852258 APJL_1035 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652035.1 1148016 D 434271 CDS YP_001652036.1 165976443 5852256 complement(1148712..1149353) 1 NC_010278.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1149353 eda 5852256 eda Actinobacillus pleuropneumoniae serovar 3 str. JL03 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001652036.1 1148712 R 434271 CDS YP_001652037.1 165976444 5852255 complement(1149368..1150282) 1 NC_010278.1 sugar kinase 1150282 rbsK1 5852255 rbsK1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sugar kinase YP_001652037.1 1149368 R 434271 CDS YP_001652038.1 165976445 5852254 complement(1150325..1150915) 1 NC_010278.1 glucuronate isomerase 1150915 uxaC 5852254 uxaC Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucuronate isomerase YP_001652038.1 1150325 R 434271 CDS YP_001652039.1 165976446 5852252 1151217..1152695 1 NC_010278.1 alpha-glucosidase 1152695 5852252 APJL_1039 Actinobacillus pleuropneumoniae serovar 3 str. JL03 alpha-glucosidase YP_001652039.1 1151217 D 434271 CDS YP_001652040.1 165976447 5852251 1152699..1152935 1 NC_010278.1 transcriptional regulator 1152935 5852251 APJL_1040 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652040.1 1152699 D 434271 CDS YP_001652041.1 165976448 5852250 1152910..1153338 1 NC_010278.1 hypothetical protein 1153338 5852250 APJL_1041 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652041.1 1152910 D 434271 CDS YP_001652042.1 165976449 5852249 1153582..1154088 1 NC_010278.1 peptide methionine sulfoxide reductase 1154088 5852249 APJL_1042 Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide methionine sulfoxide reductase YP_001652042.1 1153582 D 434271 CDS YP_001652043.1 165976450 5852247 complement(1154123..1154923) 1 NC_010278.1 putative UDP-galactose--lipooligosaccharide galactosyltransferase 1154923 lsgF 5852247 lsgF Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative UDP-galactose--lipooligosaccharide galactosyltransferase YP_001652043.1 1154123 R 434271 CDS YP_001652044.1 165976451 5852246 complement(1154923..1155804) 1 NC_010278.1 putative lipooligosaccharide galactosyltransferase 1155804 lsgE 5852246 lsgE Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative lipooligosaccharide galactosyltransferase YP_001652044.1 1154923 R 434271 CDS YP_001652045.1 165976452 5852245 complement(1155797..1156996) 1 NC_010278.1 hypothetical protein 1156996 5852245 APJL_1045 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652045.1 1155797 R 434271 CDS YP_001652046.1 165976453 5852244 complement(1156997..1157767) 1 NC_010278.1 LPS biosynthesis glycosyltransferase 1157767 lsgD 5852244 lsgD Actinobacillus pleuropneumoniae serovar 3 str. JL03 LPS biosynthesis glycosyltransferase YP_001652046.1 1156997 R 434271 CDS YP_001652047.1 165976454 5852242 complement(1157764..1158897) 1 NC_010278.1 hypothetical protein 1158897 5852242 APJL_1047 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652047.1 1157764 R 434271 CDS YP_001652048.1 165976455 5852241 complement(1158950..1159915) 1 NC_010278.1 exopolysaccharide biosynthesis protein 1159915 5852241 APJL_1048 Actinobacillus pleuropneumoniae serovar 3 str. JL03 exopolysaccharide biosynthesis protein YP_001652048.1 1158950 R 434271 CDS YP_001652049.1 165976456 5852240 1160071..1160811 1 NC_010278.1 hypothetical protein 1160811 5852240 APJL_1049 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652049.1 1160071 D 434271 CDS YP_001652050.1 165976457 5852239 complement(1160891..1163131) 1 NC_010278.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1163131 priA 5852239 priA Actinobacillus pleuropneumoniae serovar 3 str. JL03 primosome assembly protein PriA YP_001652050.1 1160891 R 434271 CDS YP_001652051.1 165976458 5852238 complement(1163192..1164349) 1 NC_010278.1 prephenate dehydratase / chorismate mutase 1164349 pheA 5852238 pheA Actinobacillus pleuropneumoniae serovar 3 str. JL03 prephenate dehydratase / chorismate mutase YP_001652051.1 1163192 R 434271 CDS YP_001652052.1 165976459 5852237 complement(1164472..1166505) 1 NC_010278.1 oligopeptidase A 1166505 prlC 5852237 prlC Actinobacillus pleuropneumoniae serovar 3 str. JL03 oligopeptidase A YP_001652052.1 1164472 R 434271 CDS YP_001652053.1 165976460 5852236 complement(1166646..1167383) 1 NC_010278.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1167383 pflA 5852236 pflA Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyruvate formate lyase-activating enzyme 1 YP_001652053.1 1166646 R 434271 CDS YP_001652054.1 165976461 5852235 complement(1167511..1169823) 1 NC_010278.1 formate acetyltransferase 1169823 pflB 5852235 pflB Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate acetyltransferase YP_001652054.1 1167511 R 434271 CDS YP_001652055.1 165976462 5852234 complement(1169916..1170740) 1 NC_010278.1 formate transporter 1170740 focA 5852234 focA Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate transporter YP_001652055.1 1169916 R 434271 CDS YP_001652056.1 165976463 5852233 1170946..1171428 1 NC_010278.1 hypothetical protein 1171428 5852233 APJL_1056 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652056.1 1170946 D 434271 CDS YP_001652057.1 165976464 5852232 complement(1171488..1172357) 1 NC_010278.1 putative metalloprotease; heat shock protein HtpX 1172357 htpX 5852232 htpX Actinobacillus pleuropneumoniae serovar 3 str. JL03 heat shock protein HtpX YP_001652057.1 1171488 R 434271 CDS YP_001652058.1 165976465 5852231 complement(1172445..1173515) 1 NC_010278.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1173515 dinP 5852231 dinP Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase IV YP_001652058.1 1172445 R 434271 CDS YP_001652059.1 165976466 5852230 1173622..1174530 1 NC_010278.1 hypothetical protein 1174530 5852230 APJL_1059 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652059.1 1173622 D 434271 CDS YP_001652060.1 165976467 5852229 complement(1174569..1175849) 1 NC_010278.1 menaquinone-specific isochorismate synthase 1175849 menF 5852229 menF Actinobacillus pleuropneumoniae serovar 3 str. JL03 menaquinone-specific isochorismate synthase YP_001652060.1 1174569 R 434271 CDS YP_001652061.1 165976468 5852228 1176013..1177230 1 NC_010278.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1177230 5852228 APJL_1061 Actinobacillus pleuropneumoniae serovar 3 str. JL03 aminotransferase AlaT YP_001652061.1 1176013 D 434271 CDS YP_001652062.1 165976469 5852226 1177274..1178167 1 NC_010278.1 permease 1178167 5852226 APJL_1062 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001652062.1 1177274 D 434271 CDS YP_001652063.1 165976470 5852224 1178168..1179034 1 NC_010278.1 permease 1179034 rarD 5852224 rarD Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001652063.1 1178168 D 434271 CDS YP_001652064.1 165976471 5852223 1179031..1179648 1 NC_010278.1 putative threonine efflux protein 1179648 5852223 APJL_1064 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative threonine efflux protein YP_001652064.1 1179031 D 434271 CDS YP_001652065.1 165976472 5852221 complement(1179729..1182575) 1 NC_010278.1 hemoglobin and hemoglobin-haptoglobin-binding protein 4 1182575 hgbA 5852221 hgbA Actinobacillus pleuropneumoniae serovar 3 str. JL03 hemoglobin and hemoglobin-haptoglobin-binding protein 4 YP_001652065.1 1179729 R 434271 CDS YP_001652066.1 165976473 5852220 complement(1182635..1183156) 1 NC_010278.1 putative heme iron utilization protein 1183156 hugZ 5852220 hugZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative heme iron utilization protein YP_001652066.1 1182635 R 434271 CDS YP_001652067.1 165976474 5852218 complement(1183360..1184106) 1 NC_010278.1 formate-dependent nitrite reductase complex NrfG subunit 1184106 nrfG 5852218 nrfG Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate-dependent nitrite reductase complex NrfG subunit YP_001652067.1 1183360 R 434271 CDS YP_001652068.1 165976475 5852217 complement(1184084..1184518) 1 NC_010278.1 formate-dependent nitrite reductase complex subunit NrfF 1184518 nrfF 5852217 nrfF Actinobacillus pleuropneumoniae serovar 3 str. JL03 formate-dependent nitrite reductase complex subunit NrfF YP_001652068.1 1184084 R 434271 CDS YP_001652069.1 165976476 5852216 complement(1184518..1185051) 1 NC_010278.1 thiol:disulfide interchange protein 1185051 dsbE2 5852216 dsbE2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol:disulfide interchange protein YP_001652069.1 1184518 R 434271 CDS YP_001652070.1 165976477 5852215 complement(1185053..1186969) 1 NC_010278.1 cytochrome c-type biogenesis protein 1186969 nfrE 5852215 nfrE Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c-type biogenesis protein YP_001652070.1 1185053 R 434271 CDS YP_001652071.1 165976478 5852214 complement(1187140..1189005) 1 NC_010278.1 glutathione-regulated potassium-efflux system protein 1189005 kefB 5852214 kefB Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutathione-regulated potassium-efflux system protein YP_001652071.1 1187140 R 434271 CDS YP_001652072.1 165976479 5852213 complement(1189094..1191622) 1 NC_010278.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 1191622 cyaA 5852213 cyaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 adenylate cyclase YP_001652072.1 1189094 R 434271 CDS YP_001652073.1 165976480 5852212 1191877..1193097 1 NC_010278.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1193097 fabB 5852212 fabB Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-oxoacyl-ACP synthase YP_001652073.1 1191877 D 434271 CDS YP_001652074.1 165976481 5852211 1193289..1193798 1 NC_010278.1 transposase and inactivated derivative 1193798 5852211 APJL_1074 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001652074.1 1193289 D 434271 CDS YP_001652075.1 165976482 5852209 1193804..1194622 1 NC_010278.1 transposase 1194622 5852209 APJL_1075 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001652075.1 1193804 D 434271 CDS YP_001652076.1 165976483 5852208 1194769..1195116 1 NC_010278.1 hypothetical protein 1195116 5852208 APJL_1076 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652076.1 1194769 D 434271 CDS YP_001652077.1 165976484 5852207 1195172..1195768 1 NC_010278.1 hypothetical protein 1195768 5852207 APJL_1077 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652077.1 1195172 D 434271 CDS YP_001652078.1 165976485 5852206 1195809..1196183 1 NC_010278.1 hypothetical protein 1196183 5852206 APJL_1078 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652078.1 1195809 D 434271 CDS YP_001652079.1 165976486 5852205 1196221..1196937 1 NC_010278.1 transcriptional regulatory protein 1196937 ygiX 5852205 ygiX Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulatory protein YP_001652079.1 1196221 D 434271 CDS YP_001652080.1 165976487 5852204 1196930..1198306 1 NC_010278.1 sensor protein 1198306 ygiY 5852204 ygiY Actinobacillus pleuropneumoniae serovar 3 str. JL03 sensor protein YP_001652080.1 1196930 D 434271 CDS YP_001652081.1 165976488 5852201 complement(1198354..1198914) 1 NC_010278.1 hypothetical protein 1198914 5852201 APJL_1081 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652081.1 1198354 R 434271 CDS YP_001652082.1 165976489 5852200 1199108..1199404 1 NC_010278.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1199404 yajC 5852200 yajC Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit YajC YP_001652082.1 1199108 D 434271 CDS YP_001652083.1 165976490 5852199 1199464..1201278 1 NC_010278.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1201278 secD 5852199 secD Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit SecD YP_001652083.1 1199464 D 434271 CDS YP_001652084.1 165976491 5852197 1201289..1202263 1 NC_010278.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1202263 secF 5852197 secF Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit SecF YP_001652084.1 1201289 D 434271 CDS YP_001652085.1 165976492 5852196 1202413..1202919 1 NC_010278.1 ferritin-like protein 1 1202919 ftnA 5852196 ftnA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferritin-like protein 1 YP_001652085.1 1202413 D 434271 CDS YP_001652086.1 165976493 5852195 1202919..1203416 1 NC_010278.1 ferritin-like protein 2 1203416 ftnB 5852195 ftnB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferritin-like protein 2 YP_001652086.1 1202919 D 434271 CDS YP_001652087.1 165976494 5852194 1203656..1204957 1 NC_010278.1 putative xanthine/uracil permease 1204957 5852194 APJL_1087 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative xanthine/uracil permease YP_001652087.1 1203656 D 434271 CDS YP_001652088.1 165976495 5852193 complement(1205012..1205602) 1 NC_010278.1 putative MAF protein 1205602 5852193 APJL_1088 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative MAF protein YP_001652088.1 1205012 R 434271 CDS YP_001652089.1 165976496 5852192 1205758..1206300 1 NC_010278.1 putative macrophage infectivity potentiator-related protein 1206300 5852192 APJL_1089 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative macrophage infectivity potentiator-related protein YP_001652089.1 1205758 D 434271 CDS YP_001652090.1 165976497 5852190 complement(1206396..1207793) 1 NC_010278.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1207793 thiI 5852190 thiI Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamine biosynthesis protein ThiI YP_001652090.1 1206396 R 434271 CDS YP_001652091.1 165976498 5852188 complement(1208031..1209329) 1 NC_010278.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1209329 purA 5852188 purA Actinobacillus pleuropneumoniae serovar 3 str. JL03 adenylosuccinate synthetase YP_001652091.1 1208031 R 434271 CDS YP_001652092.1 165976499 5852187 complement(1209516..1210403) 1 NC_010278.1 HflC protein 1210403 hflC 5852187 hflC Actinobacillus pleuropneumoniae serovar 3 str. JL03 HflC protein YP_001652092.1 1209516 R 434271 CDS YP_001652093.1 165976500 5852186 complement(1210406..1211596) 1 NC_010278.1 HflK protein 1211596 hflK 5852186 hflK Actinobacillus pleuropneumoniae serovar 3 str. JL03 HflK protein YP_001652093.1 1210406 R 434271 CDS YP_001652094.1 165976501 5852184 complement(1211774..1212091) 1 NC_010278.1 thioredoxin 1212091 trxA 5852184 trxA Actinobacillus pleuropneumoniae serovar 3 str. JL03 thioredoxin YP_001652094.1 1211774 R 434271 CDS YP_001652095.1 165976502 5852182 complement(1212227..1213519) 1 NC_010278.1 putative xanthine permease 1213519 5852182 APJL_1095 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative xanthine permease YP_001652095.1 1212227 R 434271 CDS YP_001652096.1 165976503 5852181 complement(1213681..1214832) 1 NC_010278.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1214832 metK 5852181 metK Actinobacillus pleuropneumoniae serovar 3 str. JL03 S-adenosylmethionine synthetase YP_001652096.1 1213681 R 434271 CDS YP_001652097.1 165976504 5852180 1215052..1215945 1 NC_010278.1 homocysteine/selenocysteine methylase 1215945 5852180 APJL_1097 Actinobacillus pleuropneumoniae serovar 3 str. JL03 homocysteine/selenocysteine methylase YP_001652097.1 1215052 D 434271 CDS YP_001652098.1 165976505 5852179 1216036..1217451 1 NC_010278.1 putative arginine/ornithine antiporter 1217451 arcD1 5852179 arcD1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative arginine/ornithine antiporter YP_001652098.1 1216036 D 434271 CDS YP_001652099.1 165976506 5852178 1217547..1218953 1 NC_010278.1 putative arginine/ornithine antiporter protein 1218953 arcD2 5852178 arcD2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative arginine/ornithine antiporter protein YP_001652099.1 1217547 D 434271 CDS YP_001652100.1 165976507 5852177 1218962..1219741 1 NC_010278.1 hypothetical protein 1219741 5852177 APJL_1100 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652100.1 1218962 D 434271 CDS YP_001652101.1 165976508 5852176 1219756..1220898 1 NC_010278.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 1220898 argE 5852176 argE Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetylornithine deacetylase YP_001652101.1 1219756 D 434271 CDS YP_001652102.1 165976509 5852175 complement(1220979..1221626) 1 NC_010278.1 outer membrane protein ompW 1221626 ompW 5852175 ompW Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane protein ompW YP_001652102.1 1220979 R 434271 CDS YP_001652103.1 165976510 5852174 1221887..1224460 1 NC_010278.1 ATP-dependent Clp protease subunit B 1224460 clpB 5852174 clpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent Clp protease subunit B YP_001652103.1 1221887 D 434271 CDS YP_001652104.1 165976511 5852173 complement(1224517..1225518) 1 NC_010278.1 arsenite efflux pump ACR3 1225518 acr3 5852173 acr3 Actinobacillus pleuropneumoniae serovar 3 str. JL03 arsenite efflux pump ACR3 YP_001652104.1 1224517 R 434271 CDS YP_001652105.1 165976512 5852172 complement(1225530..1225934) 1 NC_010278.1 arsenate reductase 1225934 arsC 5852172 arsC Actinobacillus pleuropneumoniae serovar 3 str. JL03 arsenate reductase YP_001652105.1 1225530 R 434271 CDS YP_001652106.1 165976513 5852171 complement(1225994..1226308) 1 NC_010278.1 putative transcriptional regulator 1226308 5852171 APJL_1106 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transcriptional regulator YP_001652106.1 1225994 R 434271 CDS YP_001652107.1 165976514 5852169 complement(1226436..1227863) 1 NC_010278.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1227863 aspA 5852169 aspA Actinobacillus pleuropneumoniae serovar 3 str. JL03 aspartate ammonia-lyase YP_001652107.1 1226436 R 434271 CDS YP_001652108.1 165976515 5852168 complement(1228004..1228285) 1 NC_010278.1 hypothetical protein 1228285 5852168 APJL_1108 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652108.1 1228004 R 434271 CDS YP_001652109.1 165976516 5852167 complement(1228359..1229396) 1 NC_010278.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1229396 purM 5852167 purM Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylaminoimidazole synthetase YP_001652109.1 1228359 R 434271 CDS YP_001652110.1 165976517 5852166 1229611..1230744 1 NC_010278.1 N-acetyl-beta-hexosaminidase 1230744 dspB 5852166 dspB Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetyl-beta-hexosaminidase YP_001652110.1 1229611 D 434271 CDS YP_001652111.1 165976518 5852165 1230892..1231560 1 NC_010278.1 queuosine biosynthesis protein QueC 1231560 queC 5852165 queC Actinobacillus pleuropneumoniae serovar 3 str. JL03 queuosine biosynthesis protein QueC YP_001652111.1 1230892 D 434271 CDS YP_001652112.1 165976519 5852164 1231553..1231975 1 NC_010278.1 6-pyruvoyl-tetrahydropterin synthase 1231975 5852164 APJL_1112 Actinobacillus pleuropneumoniae serovar 3 str. JL03 6-pyruvoyl-tetrahydropterin synthase YP_001652112.1 1231553 D 434271 CDS YP_001652113.1 165976520 5852163 1232068..1232700 1 NC_010278.1 organic radical activating enzyme 1232700 5852163 APJL_1113 Actinobacillus pleuropneumoniae serovar 3 str. JL03 organic radical activating enzyme YP_001652113.1 1232068 D 434271 CDS YP_001652114.1 165976521 5852653 complement(1232841..1233398) 1 NC_010278.1 hypothetical protein 1233398 5852653 APJL_1114 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652114.1 1232841 R 434271 CDS YP_001652115.1 165976522 5852742 complement(1233454..1233723) 1 NC_010278.1 hypothetical protein 1233723 5852742 APJL_1115 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652115.1 1233454 R 434271 CDS YP_001652116.1 165976523 5852341 complement(1234067..1235566) 1 NC_010278.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1235566 pepA 5852341 pepA Actinobacillus pleuropneumoniae serovar 3 str. JL03 leucyl aminopeptidase YP_001652116.1 1234067 R 434271 CDS YP_001652117.1 165976524 5852463 1235934..1236749 1 NC_010278.1 hypothetical protein 1236749 5852463 APJL_1117 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652117.1 1235934 D 434271 CDS YP_001652118.1 165976525 5852356 1237047..1238051 1 NC_010278.1 permease 1238051 5852356 APJL_1118 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001652118.1 1237047 D 434271 CDS YP_001652119.1 165976526 5852451 1238052..1239134 1 NC_010278.1 permease 1239134 5852451 APJL_1119 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001652119.1 1238052 D 434271 CDS YP_001652120.1 165976527 5852502 1239341..1242817 1 NC_010278.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1242817 dnaE 5852502 dnaE Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunit alpha YP_001652120.1 1239341 D 434271 CDS YP_001652121.1 165976528 5852511 complement(1243573..1243668) 1 NC_010278.1 hypothetical protein 1243668 5852511 APJL_1121 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652121.1 1243573 R 434271 CDS YP_001652122.1 165976529 5852633 complement(1243682..1244068) 1 NC_010278.1 phosphoribosylglycinamide formyltransferase 2 1244068 purT1 5852633 purT1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylglycinamide formyltransferase 2 YP_001652122.1 1243682 R 434271 CDS YP_001652123.1 165976530 5852156 complement(1244945..1246135) 1 NC_010278.1 hypothetical protein 1246135 5852156 APJL_1123 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652123.1 1244945 R 434271 CDS YP_001652124.1 165976531 5851719 complement(1246113..1246304) 1 NC_010278.1 hypothetical protein 1246304 5851719 APJL_1124 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652124.1 1246113 R 434271 CDS YP_001652125.1 165976532 5852142 complement(1247008..1248189) 1 NC_010278.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1248189 purT 5852142 purT Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylglycinamide formyltransferase 2 YP_001652125.1 1247008 R 434271 CDS YP_001652126.1 165976533 5852507 complement(1248312..1250786) 1 NC_010278.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 1250786 plsB 5852507 plsB Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerol-3-phosphate acyltransferase YP_001652126.1 1248312 R 434271 CDS YP_001652127.1 165976534 5852158 1250943..1251575 1 NC_010278.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 1251575 lexA 5852158 lexA Actinobacillus pleuropneumoniae serovar 3 str. JL03 LexA repressor YP_001652127.1 1250943 D 434271 CDS YP_001652128.1 165976535 5852730 1251635..1252315 1 NC_010278.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 1252315 mutH 5852730 mutH Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA mismatch repair protein YP_001652128.1 1251635 D 434271 CDS YP_001652129.1 165976536 5852170 1252401..1253132 1 NC_010278.1 hypothetical protein 1253132 5852170 APJL_1129 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652129.1 1252401 D 434271 CDS YP_001652130.1 165976537 5852189 1253247..1254284 1 NC_010278.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1254284 nagZ 5852189 nagZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 beta-hexosaminidase YP_001652130.1 1253247 D 434271 CDS YP_001652131.1 165976538 5852339 1254365..1255540 1 NC_010278.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1255540 rumB 5852339 rumB Actinobacillus pleuropneumoniae serovar 3 str. JL03 23S rRNA methyluridine methyltransferase YP_001652131.1 1254365 D 434271 CDS YP_001652132.1 165976539 5852811 1255747..1257057 1 NC_010278.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1257057 eno 5852811 eno Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphopyruvate hydratase YP_001652132.1 1255747 D 434271 CDS YP_001652133.1 165976540 5852804 1257082..1257762 1 NC_010278.1 hypothetical protein 1257762 5852804 APJL_1133 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652133.1 1257082 D 434271 CDS YP_001652134.1 165976541 5852132 1257776..1258186 1 NC_010278.1 hypothetical protein 1258186 5852132 APJL_1134 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652134.1 1257776 D 434271 CDS YP_001652135.1 165976542 5852131 complement(1258245..1260053) 1 NC_010278.1 ATP-dependent DNA helicase 1260053 recQ 5852131 recQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent DNA helicase YP_001652135.1 1258245 R 434271 CDS YP_001652136.1 165976543 5852803 complement(1260138..1260443) 1 NC_010278.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 1260443 cyaY 5852803 cyaY Actinobacillus pleuropneumoniae serovar 3 str. JL03 frataxin-like protein YP_001652136.1 1260138 R 434271 CDS YP_001652137.1 165976544 5851381 complement(1260452..1260922) 1 NC_010278.1 lipooligosaccharide biosynthesis protein 1260922 lpsA1 5851381 lpsA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipooligosaccharide biosynthesis protein YP_001652137.1 1260452 R 434271 CDS YP_001652138.1 165976545 5852787 complement(1260926..1261228) 1 NC_010278.1 lipooligosaccharide biosynthesis protein 1261228 lpsA2 5852787 lpsA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipooligosaccharide biosynthesis protein YP_001652138.1 1260926 R 434271 CDS YP_001652139.1 165976546 5852821 complement(1261269..1262312) 1 NC_010278.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1262312 gcp 5852821 gcp Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative DNA-binding/iron metalloprotein/AP endonuclease YP_001652139.1 1261269 R 434271 CDS YP_001652140.1 165976547 5852840 complement(1262404..1263180) 1 NC_010278.1 putative lipoprotein 1263180 5852840 APJL_1140 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative lipoprotein YP_001652140.1 1262404 R 434271 CDS YP_001652141.1 165976548 5851795 1263333..1264310 1 NC_010278.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 1264310 rluD 5851795 rluD Actinobacillus pleuropneumoniae serovar 3 str. JL03 23S rRNA pseudouridine synthase D YP_001652141.1 1263333 D 434271 CDS YP_001652142.1 165976549 5851179 complement(1264354..1265067) 1 NC_010278.1 hypothetical protein 1265067 5851179 APJL_1142 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652142.1 1264354 R 434271 CDS YP_001652143.1 165976550 5851972 complement(1265128..1266102) 1 NC_010278.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1266102 pfkA 5851972 pfkA Actinobacillus pleuropneumoniae serovar 3 str. JL03 6-phosphofructokinase YP_001652143.1 1265128 R 434271 CDS YP_001652144.1 165976551 5851561 complement(1266212..1267414) 1 NC_010278.1 cysteine desulfurase 1267414 nifS 5851561 nifS Actinobacillus pleuropneumoniae serovar 3 str. JL03 cysteine desulfurase YP_001652144.1 1266212 R 434271 CDS YP_001652145.1 165976552 5851650 complement(1267414..1268112) 1 NC_010278.1 putative endonuclease 1268112 5851650 APJL_1145 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative endonuclease YP_001652145.1 1267414 R 434271 CDS YP_001652146.1 165976553 5851041 complement(1268178..1269545) 1 NC_010278.1 Na+/alanine symporter 1269545 5851041 APJL_1146 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Na+/alanine symporter YP_001652146.1 1268178 R 434271 CDS YP_001652147.1 165976554 5851346 complement(1270012..1271064) 1 NC_010278.1 hypothetical protein 1271064 5851346 APJL_1147 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652147.1 1270012 R 434271 CDS YP_001652148.1 165976555 5850992 complement(1271158..1271532) 1 NC_010278.1 soluble cytochrome b562 1271532 cytB562 5850992 cytB562 Actinobacillus pleuropneumoniae serovar 3 str. JL03 soluble cytochrome b562 YP_001652148.1 1271158 R 434271 CDS YP_001652149.1 165976556 5851779 1271681..1273078 1 NC_010278.1 putative protease 1273078 5851779 APJL_1149 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative protease YP_001652149.1 1271681 D 434271 CDS YP_001652150.1 165976557 5851560 1273222..1274571 1 NC_010278.1 hypothetical protein 1274571 5851560 APJL_1150 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652150.1 1273222 D 434271 CDS YP_001652151.1 165976558 5851369 1274571..1275851 1 NC_010278.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 1275851 waaA 5851369 waaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-deoxy-D-manno-octulosonic-acid transferase YP_001652151.1 1274571 D 434271 CDS YP_001652152.1 165976559 5850886 1275853..1276329 1 NC_010278.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1276329 coaD 5850886 coaD Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphopantetheine adenylyltransferase YP_001652152.1 1275853 D 434271 CDS YP_001652153.1 165976560 5850714 1276332..1276886 1 NC_010278.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1276886 5850714 APJL_1153 Actinobacillus pleuropneumoniae serovar 3 str. JL03 oligoribonuclease YP_001652153.1 1276332 D 434271 CDS YP_001652154.1 165976561 5851382 1276894..1277385 1 NC_010278.1 ATP-binding protein 1277385 5851382 APJL_1154 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-binding protein YP_001652154.1 1276894 D 434271 CDS YP_001652155.1 165976562 5851511 1277409..1278554 1 NC_010278.1 N-acetylmuramoyl-L-alanine amidase 1278554 amiB 5851511 amiB Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetylmuramoyl-L-alanine amidase YP_001652155.1 1277409 D 434271 CDS YP_001652156.1 165976563 5850864 complement(1278633..1280273) 1 NC_010278.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1280273 pgi 5850864 pgi Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucose-6-phosphate isomerase YP_001652156.1 1278633 R 434271 CDS YP_001652157.1 165976564 5851638 complement(1280310..1280561) 1 NC_010278.1 hypothetical protein 1280561 5851638 APJL_1157 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652157.1 1280310 R 434271 CDS YP_001652158.1 165976565 5851826 complement(1281245..1282069) 1 NC_010278.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1282069 aroE 5851826 aroE Actinobacillus pleuropneumoniae serovar 3 str. JL03 shikimate 5-dehydrogenase YP_001652158.1 1281245 R 434271 CDS YP_001652159.1 165976566 5850968 complement(1282076..1282630) 1 NC_010278.1 hypothetical protein 1282630 5850968 APJL_1159 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652159.1 1282076 R 434271 CDS YP_001652160.1 165976567 5852529 complement(1282623..1283156) 1 NC_010278.1 DNA topoisomerase I-related protein 1283156 5852529 APJL_1160 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA topoisomerase I-related protein YP_001652160.1 1282623 R 434271 CDS YP_001652161.1 165976568 5851683 complement(1283153..1283473) 1 NC_010278.1 hypothetical protein 1283473 5851683 APJL_1161 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652161.1 1283153 R 434271 CDS YP_001652162.1 165976569 5851668 complement(1283524..1283925) 1 NC_010278.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1283925 recX 5851668 recX Actinobacillus pleuropneumoniae serovar 3 str. JL03 recombination regulator RecX YP_001652162.1 1283524 R 434271 CDS YP_001652163.1 165976570 5850771 complement(1283979..1285109) 1 NC_010278.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1285109 recA 5850771 recA Actinobacillus pleuropneumoniae serovar 3 str. JL03 recombinase A YP_001652163.1 1283979 R 434271 CDS YP_001652164.1 165976571 5851540 complement(1285223..1285828) 1 NC_010278.1 hypothetical protein 1285828 5851540 APJL_1164 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652164.1 1285223 R 434271 CDS YP_001652165.1 165976572 5851533 complement(1285806..1286774) 1 NC_010278.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I 1286774 pabB 5851533 pabB Actinobacillus pleuropneumoniae serovar 3 str. JL03 para-aminobenzoate synthase component I YP_001652165.1 1285806 R 434271 CDS YP_001652166.1 165976573 5851320 1286909..1288543 1 NC_010278.1 DNA recombination protein RmuC-like protein 1288543 rmuC 5851320 rmuC Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA recombination protein RmuC-like protein YP_001652166.1 1286909 D 434271 CDS YP_001652167.1 165976574 5850931 1288527..1289126 1 NC_010278.1 catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; putative anthranilate synthase component II 1289126 trpG 5850931 trpG Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative anthranilate synthase component II YP_001652167.1 1288527 D 434271 CDS YP_001652168.1 165976575 5851106 1289198..1289647 1 NC_010278.1 hypothetical protein 1289647 5851106 APJL_1168 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652168.1 1289198 D 434271 CDS YP_001652169.1 165976576 5850872 1289819..1291594 1 NC_010278.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1291594 aspS 5850872 aspS Actinobacillus pleuropneumoniae serovar 3 str. JL03 aspartyl-tRNA synthetase YP_001652169.1 1289819 D 434271 CDS YP_001652170.1 165976577 5851338 1291694..1292098 1 NC_010278.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1292098 ntpA 5851338 ntpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 dATP pyrophosphohydrolase YP_001652170.1 1291694 D 434271 CDS YP_001652171.1 165976578 5851783 1292122..1292862 1 NC_010278.1 hypothetical protein 1292862 5851783 APJL_1171 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652171.1 1292122 D 434271 CDS YP_001652172.1 165976579 5851703 1292995..1293519 1 NC_010278.1 hypothetical protein 1293519 5851703 APJL_1172 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652172.1 1292995 D 434271 CDS YP_001652173.1 165976580 5851627 1293579..1294181 1 NC_010278.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1294181 ruvC 5851627 ruvC Actinobacillus pleuropneumoniae serovar 3 str. JL03 Holliday junction resolvase YP_001652173.1 1293579 D 434271 CDS YP_001652174.1 165976581 5851407 complement(1294221..1295735) 1 NC_010278.1 putative zinc protease 1295735 5851407 APJL_1174 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative zinc protease YP_001652174.1 1294221 R 434271 CDS YP_001652175.1 165976582 5851746 complement(1295893..1298166) 1 NC_010278.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 1298166 metE 5851746 metE Actinobacillus pleuropneumoniae serovar 3 str. JL03 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001652175.1 1295893 R 434271 CDS YP_001652176.1 165976583 5851365 complement(1298397..1299719) 1 NC_010278.1 di- and tricarboxylate transporter 1299719 citT 5851365 citT Actinobacillus pleuropneumoniae serovar 3 str. JL03 di- and tricarboxylate transporter YP_001652176.1 1298397 R 434271 CDS YP_001652177.1 165976584 5850888 1300082..1301011 1 NC_010278.1 transcriptional regulator 1301011 lysR2 5850888 lysR2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652177.1 1300082 D 434271 CDS YP_001652178.1 165976585 5851648 complement(1301089..1302225) 1 NC_010278.1 hypothetical protein 1302225 5851648 APJL_1178 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652178.1 1301089 R 434271 CDS YP_001652179.1 165976586 5851249 complement(1302358..1303407) 1 NC_010278.1 pseudouridine synthase 1303407 5851249 APJL_1179 Actinobacillus pleuropneumoniae serovar 3 str. JL03 pseudouridine synthase YP_001652179.1 1302358 R 434271 CDS YP_001652180.1 165976587 5851619 complement(1303479..1304096) 1 NC_010278.1 putative translation factor 1304096 5851619 APJL_1180 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative translation factor YP_001652180.1 1303479 R 434271 CDS YP_001652181.1 165976588 5851423 complement(1304295..1304525) 1 NC_010278.1 hypothetical protein 1304525 5851423 APJL_1181 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652181.1 1304295 R 434271 CDS YP_001652182.1 165976589 5851111 complement(1304641..1305537) 1 NC_010278.1 iron-dependent peroxidase 1305537 5851111 APJL_1182 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-dependent peroxidase YP_001652182.1 1304641 R 434271 CDS YP_001652183.1 165976590 5851773 1305709..1307259 1 NC_010278.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1307259 trpE 5851773 trpE Actinobacillus pleuropneumoniae serovar 3 str. JL03 anthranilate synthase component I YP_001652183.1 1305709 D 434271 CDS YP_001652184.1 165976591 5851906 1307273..1307860 1 NC_010278.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1307860 pabA 5851906 pabA Actinobacillus pleuropneumoniae serovar 3 str. JL03 anthranilate synthase component II YP_001652184.1 1307273 D 434271 CDS YP_001652185.1 165976592 5851919 1307917..1308921 1 NC_010278.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1308921 trpD 5851919 trpD Actinobacillus pleuropneumoniae serovar 3 str. JL03 anthranilate phosphoribosyltransferase YP_001652185.1 1307917 D 434271 CDS YP_001652186.1 165976593 5850744 1308964..1309719 1 NC_010278.1 SAM-dependent methyltransferase 1309719 5850744 APJL_1186 Actinobacillus pleuropneumoniae serovar 3 str. JL03 SAM-dependent methyltransferase YP_001652186.1 1308964 D 434271 CDS YP_001652187.1 165976594 5850892 complement(1309746..1310831) 1 NC_010278.1 hypothetical protein 1310831 5850892 APJL_1187 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652187.1 1309746 R 434271 CDS YP_001652188.1 165976595 5850723 1311027..1311242 1 NC_010278.1 hypothetical protein 1311242 5850723 APJL_1188 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652188.1 1311027 D 434271 CDS YP_001652189.1 165976596 5850772 complement(1311331..1311780) 1 NC_010278.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1311780 rplI 5850772 rplI Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L9 YP_001652189.1 1311331 R 434271 CDS YP_001652190.1 165976597 5851956 complement(1311798..1312025) 1 NC_010278.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1312025 rpsR 5851956 rpsR Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S18 YP_001652190.1 1311798 R 434271 CDS YP_001652191.1 165976598 5851857 complement(1312000..1312374) 1 NC_010278.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 1312374 priB 5851857 priB Actinobacillus pleuropneumoniae serovar 3 str. JL03 primosomal replication protein N YP_001652191.1 1312000 R 434271 CDS YP_001652192.1 165976599 5851728 complement(1312349..1312723) 1 NC_010278.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1312723 rpsF 5851728 rpsF Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S6 YP_001652192.1 1312349 R 434271 CDS YP_001652193.1 165976600 5851985 1313012..1314298 1 NC_010278.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1314298 purD 5851985 purD Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylamine--glycine ligase YP_001652193.1 1313012 D 434271 CDS YP_001652194.1 165976601 5851713 complement(1314390..1315082) 1 NC_010278.1 nicotinamide mononucleotide transporter 1315082 5851713 APJL_1194 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nicotinamide mononucleotide transporter YP_001652194.1 1314390 R 434271 CDS YP_001652195.1 165976602 5851483 complement(1315210..1315833) 1 NC_010278.1 hypothetical protein 1315833 5851483 APJL_1195 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652195.1 1315210 R 434271 CDS YP_001652196.1 165976603 5851921 complement(1315849..1317090) 1 NC_010278.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1317090 hisS 5851921 hisS Actinobacillus pleuropneumoniae serovar 3 str. JL03 histidyl-tRNA synthetase YP_001652196.1 1315849 R 434271 CDS YP_001652197.1 165976604 5850757 complement(1317141..1317233) 1 NC_010278.1 hypothetical protein 1317233 5850757 APJL_1197 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652197.1 1317141 R 434271 CDS YP_001652198.1 165976605 5850805 complement(1317248..1318360) 1 NC_010278.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1318360 ispG 5850805 ispG Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001652198.1 1317248 R 434271 CDS YP_001652199.1 165976606 5851738 complement(1318370..1319338) 1 NC_010278.1 hypothetical protein 1319338 5851738 APJL_1199 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652199.1 1318370 R 434271 CDS YP_001652200.1 165976607 5850770 1319618..1321174 1 NC_010278.1 integral membrane sulfate transporter 1321174 5850770 APJL_1200 Actinobacillus pleuropneumoniae serovar 3 str. JL03 integral membrane sulfate transporter YP_001652200.1 1319618 D 434271 CDS YP_001652201.1 165976608 5850840 complement(1321485..1322861) 1 NC_010278.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1322861 argH 5850840 argH Actinobacillus pleuropneumoniae serovar 3 str. JL03 argininosuccinate lyase YP_001652201.1 1321485 R 434271 CDS YP_001652202.1 165976609 5851644 complement(1323142..1324182) 1 NC_010278.1 putative oxidoreductase 1324182 5851644 APJL_1202 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative oxidoreductase YP_001652202.1 1323142 R 434271 CDS YP_001652203.1 165976610 5850779 1324433..1326238 1 NC_010278.1 glutathione-regulated potassium-efflux system protein 1326238 kefBC 5850779 kefBC Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutathione-regulated potassium-efflux system protein YP_001652203.1 1324433 D 434271 CDS YP_001652204.1 165976611 5851273 1326591..1326815 1 NC_010278.1 hypothetical protein 1326815 5851273 APJL_1204 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652204.1 1326591 D 434271 CDS YP_001652205.1 165976612 5851784 1326832..1327929 1 NC_010278.1 hypothetical protein 1327929 5851784 APJL_1205 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652205.1 1326832 D 434271 CDS YP_001652206.1 165976613 5851518 complement(1328034..1328927) 1 NC_010278.1 putative HTH-type transcriptional regulator 1328927 5851518 APJL_1206 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative HTH-type transcriptional regulator YP_001652206.1 1328034 R 434271 CDS YP_001652207.1 165976614 5851017 1329051..1329503 1 NC_010278.1 hypothetical protein 1329503 5851017 APJL_1207 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652207.1 1329051 D 434271 CDS YP_001652208.1 165976615 5851281 complement(1329626..1330261) 1 NC_010278.1 hypothetical protein 1330261 5851281 APJL_1208 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652208.1 1329626 R 434271 CDS YP_001652209.1 165976616 5851155 1330598..1331449 1 NC_010278.1 putative HTH-type transcriptional regulator 1331449 yqhC 5851155 yqhC Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative HTH-type transcriptional regulator YP_001652209.1 1330598 D 434271 CDS YP_001652210.1 165976617 5851112 complement(1331508..1332407) 1 NC_010278.1 HTH-type transcriptional activator 1332407 nahR 5851112 nahR Actinobacillus pleuropneumoniae serovar 3 str. JL03 HTH-type transcriptional activator YP_001652210.1 1331508 R 434271 CDS YP_001652211.1 165976618 5851610 1332628..1333584 1 NC_010278.1 NADPH dehydrogenase 1333584 5851610 APJL_1211 Actinobacillus pleuropneumoniae serovar 3 str. JL03 NADPH dehydrogenase YP_001652211.1 1332628 D 434271 CDS YP_001652212.1 165976619 5851725 1333654..1334703 1 NC_010278.1 putative oxidoreductase 1334703 5851725 APJL_1212 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative oxidoreductase YP_001652212.1 1333654 D 434271 CDS YP_001652213.1 165976620 5851076 complement(1334762..1335631) 1 NC_010278.1 3-hydroxyisobutyrate dehydrogenase 1335631 5851076 APJL_1213 Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-hydroxyisobutyrate dehydrogenase YP_001652213.1 1334762 R 434271 CDS YP_001652214.1 165976621 5851301 1335942..1336595 1 NC_010278.1 putative NAD(P)H nitroreductase 1336595 nfnB 5851301 nfnB Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative NAD(P)H nitroreductase YP_001652214.1 1335942 D 434271 CDS YP_001652215.1 165976622 5850827 1336758..1337375 1 NC_010278.1 MarC family integral membrane protein 1337375 marC 5850827 marC Actinobacillus pleuropneumoniae serovar 3 str. JL03 MarC family integral membrane protein YP_001652215.1 1336758 D 434271 CDS YP_001652216.1 165976623 5850834 1337406..1338017 1 NC_010278.1 hypothetical protein 1338017 5850834 APJL_1216 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652216.1 1337406 D 434271 CDS YP_001652217.1 165976624 5851609 complement(1338091..1338948) 1 NC_010278.1 putative esterase 1338948 5851609 APJL_1217 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative esterase YP_001652217.1 1338091 R 434271 CDS YP_001652218.1 165976625 5851957 complement(1338963..1339757) 1 NC_010278.1 putative GST-like protein 1339757 5851957 APJL_1218 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative GST-like protein YP_001652218.1 1338963 R 434271 CDS YP_001652219.1 165976626 5851419 complement(1339933..1340352) 1 NC_010278.1 PilT domain-containing protein 1340352 pilT 5851419 pilT Actinobacillus pleuropneumoniae serovar 3 str. JL03 PilT domain-containing protein YP_001652219.1 1339933 R 434271 CDS YP_001652220.1 165976627 5851178 complement(1340362..1340619) 1 NC_010278.1 antitoxin of toxin-antitoxin stability system 1340619 5851178 APJL_1220 Actinobacillus pleuropneumoniae serovar 3 str. JL03 antitoxin of toxin-antitoxin stability system YP_001652220.1 1340362 R 434271 CDS YP_001652221.1 165976628 5850887 complement(1340769..1341887) 1 NC_010278.1 putative alcohol dehydrogenase class III 1341887 adh1 5850887 adh1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative alcohol dehydrogenase class III YP_001652221.1 1340769 R 434271 CDS YP_001652222.1 165976629 5851996 complement(1342042..1344069) 1 NC_010278.1 choline-glycine betaine transporter 1344069 5851996 APJL_1222 Actinobacillus pleuropneumoniae serovar 3 str. JL03 choline-glycine betaine transporter YP_001652222.1 1342042 R 434271 CDS YP_001652223.1 165976630 5851729 1344366..1345076 1 NC_010278.1 hypothetical protein 1345076 5851729 APJL_1223 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652223.1 1344366 D 434271 CDS YP_001652224.1 165976631 5851882 1345076..1345912 1 NC_010278.1 hypothetical protein 1345912 5851882 APJL_1224 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652224.1 1345076 D 434271 CDS YP_001652225.1 165976632 5851978 complement(1345991..1346938) 1 NC_010278.1 potassium-tellurite ethidium and proflavin transporter 1346938 tehA 5851978 tehA Actinobacillus pleuropneumoniae serovar 3 str. JL03 potassium-tellurite ethidium and proflavin transporter YP_001652225.1 1345991 R 434271 CDS YP_001652226.1 165976633 5851864 complement(1347037..1347687) 1 NC_010278.1 hypothetical protein 1347687 5851864 APJL_1226 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652226.1 1347037 R 434271 CDS YP_001652227.1 165976634 5851830 complement(1347925..1348488) 1 NC_010278.1 flavin reductase domain-containing protein 1348488 5851830 APJL_1227 Actinobacillus pleuropneumoniae serovar 3 str. JL03 flavin reductase domain-containing protein YP_001652227.1 1347925 R 434271 CDS YP_001652228.1 165976635 5851814 complement(1348575..1350419) 1 NC_010278.1 ABC transporter ATP-binding protein 1350419 5851814 APJL_1228 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001652228.1 1348575 R 434271 CDS YP_001652229.1 165976636 5851794 complement(1350525..1351034) 1 NC_010278.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1351034 luxS 5851794 luxS Actinobacillus pleuropneumoniae serovar 3 str. JL03 S-ribosylhomocysteinase YP_001652229.1 1350525 R 434271 CDS YP_001652230.1 165976637 5851841 complement(1351089..1353617) 1 NC_010278.1 hypothetical protein 1353617 5851841 APJL_1230 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652230.1 1351089 R 434271 CDS YP_001652231.1 165976638 5851786 complement(1353903..1354352) 1 NC_010278.1 ferric uptake regulation protein 1354352 fur 5851786 fur Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferric uptake regulation protein YP_001652231.1 1353903 R 434271 CDS YP_001652232.1 165976639 5851897 complement(1354381..1354905) 1 NC_010278.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 1354905 fldA 5851897 fldA Actinobacillus pleuropneumoniae serovar 3 str. JL03 flavodoxin FldA YP_001652232.1 1354381 R 434271 CDS YP_001652233.1 165976640 5851940 complement(1354927..1355220) 1 NC_010278.1 LexA regulated protein 1355220 5851940 APJL_1233 Actinobacillus pleuropneumoniae serovar 3 str. JL03 LexA regulated protein YP_001652233.1 1354927 R 434271 CDS YP_001652234.1 165976641 5851992 complement(1355420..1355896) 1 NC_010278.1 hypothetical protein 1355896 5851992 APJL_1234 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652234.1 1355420 R 434271 CDS YP_001652235.1 165976642 5851827 1355988..1356989 1 NC_010278.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1356989 5851827 APJL_1235 Actinobacillus pleuropneumoniae serovar 3 str. JL03 aspartate-semialdehyde dehydrogenase YP_001652235.1 1355988 D 434271 CDS YP_001652236.1 165976643 5851744 1357050..1358345 1 NC_010278.1 xanthine/uracil family permease 1358345 5851744 APJL_1236 Actinobacillus pleuropneumoniae serovar 3 str. JL03 xanthine/uracil family permease YP_001652236.1 1357050 D 434271 CDS YP_001652237.1 165976644 5852030 1358455..1358805 1 NC_010278.1 hypothetical protein 1358805 5852030 APJL_1237 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652237.1 1358455 D 434271 CDS YP_001652238.1 165976645 5851944 1358805..1359992 1 NC_010278.1 flavoprotein 1359992 5851944 APJL_1238 Actinobacillus pleuropneumoniae serovar 3 str. JL03 flavoprotein YP_001652238.1 1358805 D 434271 CDS YP_001652239.1 165976646 5851612 complement(1360070..1360288) 1 NC_010278.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1360288 infA 5851612 infA Actinobacillus pleuropneumoniae serovar 3 str. JL03 translation initiation factor IF-1 YP_001652239.1 1360070 R 434271 CDS YP_001652240.1 165976647 5851697 complement(1360380..1361042) 1 NC_010278.1 AphA (smp-like) protein 1361042 aphA 5851697 aphA Actinobacillus pleuropneumoniae serovar 3 str. JL03 AphA (smp-like) protein YP_001652240.1 1360380 R 434271 CDS YP_001652241.1 165976648 5851855 1361135..1362004 1 NC_010278.1 phosphoserine phosphatase 1362004 serB 5851855 serB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoserine phosphatase YP_001652241.1 1361135 D 434271 CDS YP_001652242.1 165976649 5851968 1362054..1362545 1 NC_010278.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 1362545 5851968 APJL_1242 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative nucleotide-binding protein YP_001652242.1 1362054 D 434271 CDS YP_001652243.1 165976650 5851736 1362594..1362791 1 NC_010278.1 hypothetical protein 1362791 5851736 APJL_1243 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652243.1 1362594 D 434271 CDS YP_001652244.1 165976651 5851878 1362899..1365298 1 NC_010278.1 glucan phosphorylase 1365298 glgP 5851878 glgP Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucan phosphorylase YP_001652244.1 1362899 D 434271 CDS YP_001652245.1 165976652 5851989 complement(1365376..1368093) 1 NC_010278.1 ATP-dependent transcriptional regulator 1368093 malT 5851989 malT Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent transcriptional regulator YP_001652245.1 1365376 R 434271 CDS YP_001652246.1 165976653 5851748 complement(1368208..1369092) 1 NC_010278.1 maltose regulon periplasmic protein 1369092 5851748 APJL_1246 Actinobacillus pleuropneumoniae serovar 3 str. JL03 maltose regulon periplasmic protein YP_001652246.1 1368208 R 434271 CDS YP_001652247.1 165976654 5851495 complement(1369164..1370456) 1 NC_010278.1 porin involved in the transport of maltose and maltodextrins; maltoporin 1370456 lamB 5851495 lamB Actinobacillus pleuropneumoniae serovar 3 str. JL03 maltoporin YP_001652247.1 1369164 R 434271 CDS YP_001652248.1 165976655 5851936 complement(1370526..1371665) 1 NC_010278.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 1371665 malK 5851936 malK Actinobacillus pleuropneumoniae serovar 3 str. JL03 maltose/maltodextrin transporter ATP-binding protein YP_001652248.1 1370526 R 434271 CDS YP_001652249.1 165976656 5852001 1371996..1373180 1 NC_010278.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 1373180 malE 5852001 malE Actinobacillus pleuropneumoniae serovar 3 str. JL03 maltose ABC transporter periplasmic protein YP_001652249.1 1371996 D 434271 CDS YP_001652250.1 165976657 5851278 1373259..1374809 1 NC_010278.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 1374809 malF 5851278 malF Actinobacillus pleuropneumoniae serovar 3 str. JL03 maltose transporter membrane protein YP_001652250.1 1373259 D 434271 CDS YP_001652251.1 165976658 5851475 1374860..1375750 1 NC_010278.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 1375750 malG 5851475 malG Actinobacillus pleuropneumoniae serovar 3 str. JL03 maltose transporter permease YP_001652251.1 1374860 D 434271 CDS YP_001652252.1 165976659 5851948 1375841..1377859 1 NC_010278.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1377859 malQ 5851948 malQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-alpha-glucanotransferase YP_001652252.1 1375841 D 434271 CDS YP_001652253.1 165976660 5852007 1378077..1379663 1 NC_010278.1 carbon starvation protein, membrane protein 1379663 5852007 APJL_1253 Actinobacillus pleuropneumoniae serovar 3 str. JL03 carbon starvation protein, membrane protein YP_001652253.1 1378077 D 434271 CDS YP_001652254.1 165976661 5851923 1379729..1380523 1 NC_010278.1 putative deoxyribonuclease 1380523 5851923 APJL_1254 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative deoxyribonuclease YP_001652254.1 1379729 D 434271 CDS YP_001652255.1 165976662 5852839 complement(1380585..1381955) 1 NC_010278.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1381955 lpd 5852839 lpd Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutathione reductase YP_001652255.1 1380585 R 434271 CDS YP_001652256.1 165976663 5851993 complement(1382041..1382559) 1 NC_010278.1 hypothetical protein 1382559 5851993 APJL_1256 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652256.1 1382041 R 434271 CDS YP_001652257.1 165976664 5851887 complement(1382661..1383299) 1 NC_010278.1 putative NAD(P)H nitroreductase 1383299 5851887 APJL_1257 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative NAD(P)H nitroreductase YP_001652257.1 1382661 R 434271 CDS YP_001652258.1 165976665 5851849 complement(1383462..1383755) 1 NC_010278.1 hypothetical protein 1383755 5851849 APJL_1258 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652258.1 1383462 R 434271 CDS YP_001652259.1 165976666 5851764 complement(1383755..1384414) 1 NC_010278.1 AzlC family protein 1384414 5851764 APJL_1259 Actinobacillus pleuropneumoniae serovar 3 str. JL03 AzlC family protein YP_001652259.1 1383755 R 434271 CDS YP_001652260.1 165976667 5851862 complement(1384488..1385288) 1 NC_010278.1 peptide transport system ATP-binding protein 1385288 sapF 5851862 sapF Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide transport system ATP-binding protein YP_001652260.1 1384488 R 434271 CDS YP_001652261.1 165976668 5851931 complement(1385404..1386480) 1 NC_010278.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 1386480 fba 5851931 fba Actinobacillus pleuropneumoniae serovar 3 str. JL03 fructose-bisphosphate aldolase YP_001652261.1 1385404 R 434271 CDS YP_001652262.1 165976669 5851506 complement(1386581..1387756) 1 NC_010278.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1387756 pgk 5851506 pgk Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoglycerate kinase YP_001652262.1 1386581 R 434271 CDS YP_001652263.1 165976670 5851969 complement(1387914..1389302) 1 NC_010278.1 hypothetical protein 1389302 5851969 APJL_1263 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652263.1 1387914 R 434271 CDS YP_001652264.1 165976671 5851865 complement(1389535..1390809) 1 NC_010278.1 di- and tricarboxylate transporter 1390809 5851865 APJL_1264 Actinobacillus pleuropneumoniae serovar 3 str. JL03 di- and tricarboxylate transporter YP_001652264.1 1389535 R 434271 CDS YP_001652265.1 165976672 5851941 complement(1391114..1392505) 1 NC_010278.1 di- and tricarboxylate transporter 1392505 5851941 APJL_1265 Actinobacillus pleuropneumoniae serovar 3 str. JL03 di- and tricarboxylate transporter YP_001652265.1 1391114 R 434271 CDS YP_001652266.1 165976673 5852033 complement(1392701..1394614) 1 NC_010278.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1394614 parE 5852033 parE Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA topoisomerase IV subunit B YP_001652266.1 1392701 R 434271 CDS YP_001652267.1 165976674 5851685 complement(1394692..1395984) 1 NC_010278.1 phosphate regulon sensor protein 1395984 phoR 5851685 phoR Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate regulon sensor protein YP_001652267.1 1394692 R 434271 CDS YP_001652268.1 165976675 5852037 complement(1395984..1396625) 1 NC_010278.1 phosphate regulon transcriptional regulatory protein 1396625 phoB 5852037 phoB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate regulon transcriptional regulatory protein YP_001652268.1 1395984 R 434271 CDS YP_001652269.1 165976676 5851669 complement(1396800..1397579) 1 NC_010278.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1397579 pstB 5851669 pstB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate transporter ATP-binding protein YP_001652269.1 1396800 R 434271 CDS YP_001652270.1 165976677 5852055 complement(1397588..1398439) 1 NC_010278.1 phosphate ABC transporter permease 1398439 pstA 5852055 pstA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate ABC transporter permease YP_001652270.1 1397588 R 434271 CDS YP_001652271.1 165976678 5852043 complement(1398439..1399392) 1 NC_010278.1 phosphate transport system permease protein 1399392 pstC 5852043 pstC Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate transport system permease protein YP_001652271.1 1398439 R 434271 CDS YP_001652272.1 165976679 5852046 complement(1399541..1400584) 1 NC_010278.1 phosphate-binding periplasmic protein 1400584 pstS 5852046 pstS Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate-binding periplasmic protein YP_001652272.1 1399541 R 434271 CDS YP_001652273.1 165976680 5852063 complement(1400706..1401092) 1 NC_010278.1 heavy metal-dependent transcriptional regulator 1401092 5852063 APJL_1273 Actinobacillus pleuropneumoniae serovar 3 str. JL03 heavy metal-dependent transcriptional regulator YP_001652273.1 1400706 R 434271 CDS YP_001652274.1 165976681 5852050 1401178..1401630 1 NC_010278.1 metal-binding protein 1401630 5852050 APJL_1274 Actinobacillus pleuropneumoniae serovar 3 str. JL03 metal-binding protein YP_001652274.1 1401178 D 434271 CDS YP_001652275.1 165976682 5852069 1401648..1401848 1 NC_010278.1 cation transport ATPase 1401848 5852069 APJL_1275 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cation transport ATPase YP_001652275.1 1401648 D 434271 CDS YP_001652276.1 165976683 5852042 1402087..1404237 1 NC_010278.1 copper-transporting P-type ATPase 1404237 copA 5852042 copA Actinobacillus pleuropneumoniae serovar 3 str. JL03 copper-transporting P-type ATPase YP_001652276.1 1402087 D 434271 CDS YP_001652277.1 165976684 5852073 complement(1404335..1405156) 1 NC_010278.1 putative oxidoreductase 1405156 5852073 APJL_1277 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative oxidoreductase YP_001652277.1 1404335 R 434271 CDS YP_001652278.1 165976685 5852072 complement(1405184..1405747) 1 NC_010278.1 nitroreductase 1405747 5852072 APJL_1278 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitroreductase YP_001652278.1 1405184 R 434271 CDS YP_001652279.1 165976686 5852053 1405862..1407718 1 NC_010278.1 protease IV, signal peptide peptidase 1407718 sppA 5852053 sppA Actinobacillus pleuropneumoniae serovar 3 str. JL03 protease IV, signal peptide peptidase YP_001652279.1 1405862 D 434271 CDS YP_001652280.1 165976687 5852058 1407877..1408620 1 NC_010278.1 ribonuclease 1408620 5852058 APJL_1280 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease YP_001652280.1 1407877 D 434271 CDS YP_001652281.1 165976688 5852060 1408651..1409142 1 NC_010278.1 hypothetical protein 1409142 sprT 5852060 sprT Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652281.1 1408651 D 434271 CDS YP_001652282.1 165976689 5852061 1409247..1410533 1 NC_010278.1 NADH dehydrogenase 1410533 ndh 5852061 ndh Actinobacillus pleuropneumoniae serovar 3 str. JL03 NADH dehydrogenase YP_001652282.1 1409247 D 434271 CDS YP_001652283.1 165976690 5852065 complement(1410723..1413062) 1 NC_010278.1 transcriptional accessory protein 1413062 5852065 APJL_1283 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional accessory protein YP_001652283.1 1410723 R 434271 CDS YP_001652284.1 165976691 5852067 complement(1413137..1413685) 1 NC_010278.1 putative fimbrial biogenesis and twitching motility protein PilF-like protein 1413685 pilF 5852067 pilF Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative fimbrial biogenesis and twitching motility protein PilF-like protein YP_001652284.1 1413137 R 434271 CDS YP_001652285.1 165976692 5852088 complement(1413739..1414920) 1 NC_010278.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1414920 5852088 APJL_1285 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosomal RNA large subunit methyltransferase N YP_001652285.1 1413739 R 434271 CDS YP_001652286.1 165976693 5852856 1415825..1417264 1 NC_010278.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1417264 gltX 5852856 gltX Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutamyl-tRNA synthetase YP_001652286.1 1415825 D 434271 CDS YP_001652287.1 165976694 5852092 1417602..1417853 1 NC_010278.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 1417853 5852092 APJL_1287 Actinobacillus pleuropneumoniae serovar 3 str. JL03 antitoxin YefM YP_001652287.1 1417602 D 434271 CDS YP_001652288.1 165976695 5852114 1417850..1418110 1 NC_010278.1 toxin YoeB 1418110 yoeB 5852114 yoeB Actinobacillus pleuropneumoniae serovar 3 str. JL03 toxin YoeB YP_001652288.1 1417850 D 434271 CDS YP_001652289.1 165976696 5852104 complement(1418268..1418435) 1 NC_010278.1 hypothetical protein 1418435 5852104 APJL_1289 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652289.1 1418268 R 434271 CDS YP_001652290.1 165976697 5852106 complement(1418437..1419417) 1 NC_010278.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1419417 lpxK 5852106 lpxK Actinobacillus pleuropneumoniae serovar 3 str. JL03 tetraacyldisaccharide 4'-kinase YP_001652290.1 1418437 R 434271 CDS YP_001652291.1 165976698 5852105 complement(1419511..1420647) 1 NC_010278.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1420647 clpX 5852105 clpX Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent protease ATP-binding subunit ClpX YP_001652291.1 1419511 R 434271 CDS YP_001652292.1 165976699 5852107 complement(1420770..1421360) 1 NC_010278.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1421360 clpP 5852107 clpP Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent Clp protease proteolytic subunit YP_001652292.1 1420770 R 434271 CDS YP_001652293.1 165976700 5852108 1421484..1421876 1 NC_010278.1 hypothetical protein 1421876 sufE 5852108 sufE Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652293.1 1421484 D 434271 CDS YP_001652294.1 165976701 5852124 complement(1422235..1423008) 1 NC_010278.1 DNA polymerase III subunit epsilon 1423008 dnaQ 5852124 dnaQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunit epsilon YP_001652294.1 1422235 R 434271 CDS YP_001652295.1 165976702 5852123 complement(1423095..1424765) 1 NC_010278.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1424765 5852123 APJL_1295 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative ABC transporter ATP-binding protein YP_001652295.1 1423095 R 434271 CDS YP_001652296.1 165976703 5852120 1424930..1425268 1 NC_010278.1 putative gamma-carboxymuconolactone decarboxylase subunit 1425268 5852120 APJL_1296 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative gamma-carboxymuconolactone decarboxylase subunit YP_001652296.1 1424930 D 434271 CDS YP_001652297.1 165976704 5852146 1425261..1425629 1 NC_010278.1 rhodanese-related sulfurtransferase 1425629 5852146 APJL_1297 Actinobacillus pleuropneumoniae serovar 3 str. JL03 rhodanese-related sulfurtransferase YP_001652297.1 1425261 D 434271 CDS YP_001652298.1 165976705 5852627 1425738..1426058 1 NC_010278.1 hypothetical protein 1426058 5852627 APJL_1298 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652298.1 1425738 D 434271 CDS YP_001652299.1 165976706 5852655 complement(1426116..1427390) 1 NC_010278.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1427390 murA 5852655 murA Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001652299.1 1426116 R 434271 CDS YP_001652300.1 165976707 5852650 complement(1427510..1427770) 1 NC_010278.1 transcriptional regulator 1427770 5852650 APJL_1300 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652300.1 1427510 R 434271 CDS YP_001652301.1 165976708 5852681 complement(1427783..1428136) 1 NC_010278.1 putative anti-sigma factor B antagonist 1428136 5852681 APJL_1301 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative anti-sigma factor B antagonist YP_001652301.1 1427783 R 434271 CDS YP_001652302.1 165976709 5852698 complement(1428146..1428784) 1 NC_010278.1 organic solvent resistance ABC transporter auxiliary protein 1428784 5852698 APJL_1302 Actinobacillus pleuropneumoniae serovar 3 str. JL03 organic solvent resistance ABC transporter auxiliary protein YP_001652302.1 1428146 R 434271 CDS YP_001652303.1 165976710 5852776 complement(1428856..1429383) 1 NC_010278.1 organic solvent resistance ABC transporter periplasmic protein 1429383 5852776 APJL_1303 Actinobacillus pleuropneumoniae serovar 3 str. JL03 organic solvent resistance ABC transporter periplasmic protein YP_001652303.1 1428856 R 434271 CDS YP_001652304.1 165976711 5852553 complement(1429402..1430178) 1 NC_010278.1 permease 1430178 5852553 APJL_1304 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001652304.1 1429402 R 434271 CDS YP_001652305.1 165976712 5852284 complement(1430171..1430974) 1 NC_010278.1 ABC transporter ATP-binding protein 1430974 5852284 APJL_1305 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001652305.1 1430171 R 434271 CDS YP_001652306.1 165976713 5852293 1431235..1432629 1 NC_010278.1 serine protease 1432629 degP 5852293 degP Actinobacillus pleuropneumoniae serovar 3 str. JL03 serine protease YP_001652306.1 1431235 D 434271 CDS YP_001652307.1 165976714 5852434 complement(1432668..1433555) 1 NC_010278.1 hypothetical protein 1433555 5852434 APJL_1307 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652307.1 1432668 R 434271 CDS YP_001652308.1 165976715 5852590 complement(1433555..1434016) 1 NC_010278.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 1434016 argR 5852590 argR Actinobacillus pleuropneumoniae serovar 3 str. JL03 arginine repressor YP_001652308.1 1433555 R 434271 CDS YP_001652309.1 165976716 5852257 1434210..1435163 1 NC_010278.1 oxidizes malate to oxaloacetate; malate dehydrogenase 1435163 mdh 5852257 mdh Actinobacillus pleuropneumoniae serovar 3 str. JL03 malate dehydrogenase YP_001652309.1 1434210 D 434271 CDS YP_001652310.1 165976717 5852316 1435253..1435522 1 NC_010278.1 hypothetical protein 1435522 5852316 APJL_1310 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652310.1 1435253 D 434271 CDS YP_001652311.1 165976718 5852328 complement(1435590..1436234) 1 NC_010278.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1436234 adk 5852328 adk Actinobacillus pleuropneumoniae serovar 3 str. JL03 adenylate kinase YP_001652311.1 1435590 R 434271 CDS YP_001652312.1 165976719 5852337 complement(1436386..1438509) 1 NC_010278.1 iron-regulated outer membrane protein 1438509 5852337 APJL_1312 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-regulated outer membrane protein YP_001652312.1 1436386 R 434271 CDS YP_001652313.1 165976720 5852487 complement(1438686..1439966) 1 NC_010278.1 permease and signal transducer 1439966 ampG 5852487 ampG Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease and signal transducer YP_001652313.1 1438686 R 434271 CDS YP_001652314.1 165976721 5852495 complement(1440105..1441121) 1 NC_010278.1 UDP-glucose-4-epimerase 1441121 galE 5852495 galE Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-glucose-4-epimerase YP_001652314.1 1440105 R 434271 CDS YP_001652315.1 165976722 5852592 complement(1441187..1443235) 1 NC_010278.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1443235 ligA 5852592 ligA Actinobacillus pleuropneumoniae serovar 3 str. JL03 NAD-dependent DNA ligase LigA YP_001652315.1 1441187 R 434271 CDS YP_001652316.1 165976723 5852119 complement(1443299..1444309) 1 NC_010278.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 1444309 zipA 5852119 zipA Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein ZipA YP_001652316.1 1443299 R 434271 CDS YP_001652317.1 165976724 5852157 1444429..1445310 1 NC_010278.1 putative role in sulfur assimilation; putative sulfate transport protein CysZ 1445310 cysZ 5852157 cysZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sulfate transport protein CysZ YP_001652317.1 1444429 D 434271 CDS YP_001652318.1 165976725 5852382 complement(1445370..1445696) 1 NC_010278.1 hypothetical protein 1445696 5852382 APJL_1318 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652318.1 1445370 R 434271 CDS YP_001652319.1 165976726 5852571 complement(1445788..1447242) 1 NC_010278.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1447242 gnd 5852571 gnd Actinobacillus pleuropneumoniae serovar 3 str. JL03 6-phosphogluconate dehydrogenase YP_001652319.1 1445788 R 434271 CDS YP_001652320.1 165976727 5852160 complement(1447455..1447955) 1 NC_010278.1 hypothetical protein 1447955 5852160 APJL_1320 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652320.1 1447455 R 434271 CDS YP_001652321.1 165976728 5852616 complement(1448094..1448783) 1 NC_010278.1 RacX protein 1448783 racX 5852616 racX Actinobacillus pleuropneumoniae serovar 3 str. JL03 RacX protein YP_001652321.1 1448094 R 434271 CDS YP_001652322.1 165976729 5852138 complement(1448886..1450205) 1 NC_010278.1 putative transport protein 1450205 5852138 APJL_1322 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transport protein YP_001652322.1 1448886 R 434271 CDS YP_001652323.1 165976730 5852144 complement(1450338..1451036) 1 NC_010278.1 6-phosphogluconolactonase 1451036 nagB1 5852144 nagB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 6-phosphogluconolactonase YP_001652323.1 1450338 R 434271 CDS YP_001652324.1 165976731 5852134 complement(1451123..1452610) 1 NC_010278.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1452610 zwf 5852134 zwf Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucose-6-phosphate 1-dehydrogenase YP_001652324.1 1451123 R 434271 CDS YP_001652325.1 165976732 5852198 complement(1452682..1453497) 1 NC_010278.1 3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase 1453497 cysQ 5852198 cysQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase YP_001652325.1 1452682 R 434271 CDS YP_001652326.1 165976733 5852139 complement(1453510..1454067) 1 NC_010278.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 1454067 nudE 5852139 nudE Actinobacillus pleuropneumoniae serovar 3 str. JL03 ADP-ribose diphosphatase NudE YP_001652326.1 1453510 R 434271 CDS YP_001652327.1 165976734 5852203 1454210..1454614 1 NC_010278.1 heat shock protein 15-like protein 1454614 hslR 5852203 hslR Actinobacillus pleuropneumoniae serovar 3 str. JL03 heat shock protein 15-like protein YP_001652327.1 1454210 D 434271 CDS YP_001652328.1 165976735 5852489 1454745..1455635 1 NC_010278.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 1455635 hslO 5852489 hslO Actinobacillus pleuropneumoniae serovar 3 str. JL03 Hsp33-like chaperonin YP_001652328.1 1454745 D 434271 CDS YP_001652329.1 165976736 5852133 complement(1455703..1457037) 1 NC_010278.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 1457037 dcuB2 5852133 dcuB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 anaerobic C4-dicarboxylate transporter YP_001652329.1 1455703 R 434271 CDS YP_001652330.1 165976737 5852147 1457267..1457437 1 NC_010278.1 hypothetical protein 1457437 5852147 APJL_1330 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652330.1 1457267 D 434271 CDS YP_001652331.1 165976738 5852148 1457902..1458906 1 NC_010278.1 ornithine carbamoyltransferase 1458906 argF 5852148 argF Actinobacillus pleuropneumoniae serovar 3 str. JL03 ornithine carbamoyltransferase YP_001652331.1 1457902 D 434271 CDS YP_001652332.1 165976739 5852151 1458928..1459875 1 NC_010278.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 1459875 arcC 5852151 arcC Actinobacillus pleuropneumoniae serovar 3 str. JL03 carbamate kinase YP_001652332.1 1458928 D 434271 CDS YP_001652333.1 165976740 5852159 complement(1460123..1461544) 1 NC_010278.1 phosphotransferase system enzyme II,sucrose-specific, factor IIBC 1461544 ptsB 5852159 ptsB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphotransferase system enzyme II,sucrose-specific, factor IIBC YP_001652333.1 1460123 R 434271 CDS YP_001652334.1 165976741 5852162 complement(1461734..1462378) 1 NC_010278.1 thiamin ABC transporterATP-binding protein 1462378 thiQ 5852162 thiQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamin ABC transporterATP-binding protein YP_001652334.1 1461734 R 434271 CDS YP_001652335.1 165976742 5852185 complement(1462375..1464000) 1 NC_010278.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1464000 thiP 5852185 thiP Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiamine transporter membrane protein YP_001652335.1 1462375 R 434271 CDS YP_001652336.1 165976743 5852243 1464237..1464494 1 NC_010278.1 PTS system phosphocarrier protein HPr 1464494 ptsH 5852243 ptsH Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system phosphocarrier protein HPr YP_001652336.1 1464237 D 434271 CDS YP_001652337.1 165976744 5852248 1464618..1466339 1 NC_010278.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 1466339 ptsI 5852248 ptsI Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoenolpyruvate-protein phosphotransferase YP_001652337.1 1464618 D 434271 CDS YP_001652338.1 165976745 5852310 1466424..1466924 1 NC_010278.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 1466924 crr 5852310 crr Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system glucose-specific transporter YP_001652338.1 1466424 D 434271 CDS YP_001652339.1 165976746 5852317 1467146..1468537 1 NC_010278.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1468537 5852317 APJL_1339 Actinobacillus pleuropneumoniae serovar 3 str. JL03 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001652339.1 1467146 D 434271 CDS YP_001652340.1 165976747 5852401 1468739..1470937 1 NC_010278.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 1470937 uvrD 5852401 uvrD Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-dependent helicase II YP_001652340.1 1468739 D 434271 CDS YP_001652341.1 165976748 5852465 1471141..1471950 1 NC_010278.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 1471950 hypB 5852465 hypB Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase nickel incorporation protein HypB YP_001652341.1 1471141 D 434271 CDS YP_001652342.1 165976749 5852469 1471962..1473077 1 NC_010278.1 hydrogenase maturation factor 1473077 hypD 5852469 hypD Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase maturation factor YP_001652342.1 1471962 D 434271 CDS YP_001652343.1 165976750 5852471 1473151..1474092 1 NC_010278.1 hydrogenase maturation factor 1474092 hypE 5852471 hypE Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase maturation factor YP_001652343.1 1473151 D 434271 CDS YP_001652344.1 165976751 5852537 complement(1474432..1475865) 1 NC_010278.1 RTX-III toxin determinant D 1475865 apxIIID 5852537 apxIIID Actinobacillus pleuropneumoniae serovar 3 str. JL03 RTX-III toxin determinant D YP_001652344.1 1474432 R 434271 CDS YP_001652345.1 165976752 5852539 complement(1475877..1478000) 1 NC_010278.1 toxin RTX-III translocation ATP-binding protein (RTX-III toxin determinant B) 1478000 apxIIIB 5852539 apxIIIB Actinobacillus pleuropneumoniae serovar 3 str. JL03 toxin RTX-III translocation ATP-binding protein (RTX-III toxin determinant B) YP_001652345.1 1475877 R 434271 CDS YP_001652346.1 165976753 5852555 complement(1478069..1481227) 1 NC_010278.1 RTX-III toxin determinant A from serotype 8 1481227 apxIIIA 5852555 apxIIIA Actinobacillus pleuropneumoniae serovar 3 str. JL03 RTX-III toxin determinant A from serotype 8 YP_001652346.1 1478069 R 434271 CDS YP_001652347.1 165976754 5852566 complement(1481231..1481647) 1 NC_010278.1 hemolysin-activating lysine-acyltransferase HlyC 1481647 apxIIIC 5852566 apxIIIC Actinobacillus pleuropneumoniae serovar 3 str. JL03 hemolysin-activating lysine-acyltransferase HlyC YP_001652347.1 1481231 R 434271 CDS YP_001652348.1 165976755 5852612 complement(1482195..1484498) 1 NC_010278.1 hydrogenase maturation factor 1484498 hypF 5852612 hypF Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase maturation factor YP_001652348.1 1482195 R 434271 CDS YP_001652349.1 165976756 5852618 1484733..1485875 1 NC_010278.1 involved in hydrogen uptake; hydrogenase 2 small subunit 1485875 hyaA 5852618 hyaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase 2 small subunit YP_001652349.1 1484733 D 434271 CDS YP_001652350.1 165976757 5852625 1485868..1486905 1 NC_010278.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 1486905 hybA2 5852625 hybA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase 2 protein HybA YP_001652350.1 1485868 D 434271 CDS YP_001652351.1 165976758 5852691 1486898..1488079 1 NC_010278.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit 1488079 cytB 5852691 cytB Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative hydrogenase 2 b cytochrome subunit YP_001652351.1 1486898 D 434271 CDS YP_001652352.1 165976759 5852694 1488076..1489785 1 NC_010278.1 involved in hydrogen uptake; hydrogenase 2 large subunit 1489785 hyaB 5852694 hyaB Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase 2 large subunit YP_001652352.1 1488076 D 434271 CDS YP_001652353.1 165976760 5852696 1489785..1490282 1 NC_010278.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 1490282 hybD 5852696 hybD Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase 2 maturation endopeptidase YP_001652353.1 1489785 D 434271 CDS YP_001652354.1 165976761 5852707 1490275..1490778 1 NC_010278.1 hydrogenase 2-specific chaperone 1490778 hybE 5852707 hybE Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase 2-specific chaperone YP_001652354.1 1490275 D 434271 CDS YP_001652355.1 165976762 5852710 1490806..1491084 1 NC_010278.1 hydrogenase 2 accessory protein HypG 1491084 hypC 5852710 hypC Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase 2 accessory protein HypG YP_001652355.1 1490806 D 434271 CDS YP_001652356.1 165976763 5852722 complement(1491179..1491520) 1 NC_010278.1 hydrogenase nickel incorporation protein hybF 1491520 hybF 5852722 hybF Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydrogenase nickel incorporation protein hybF YP_001652356.1 1491179 R 434271 CDS YP_001652357.1 165976764 5852281 complement(1492435..1495884) 1 NC_010278.1 transcription repair coupling factor 1495884 mfd 5852281 mfd Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcription repair coupling factor YP_001652357.1 1492435 R 434271 CDS YP_001652358.1 165976765 5852576 1495986..1498595 1 NC_010278.1 aminopeptidase N 1498595 pepN 5852576 pepN Actinobacillus pleuropneumoniae serovar 3 str. JL03 aminopeptidase N YP_001652358.1 1495986 D 434271 CDS YP_001652359.1 165976766 5852783 complement(1498733..1499323) 1 NC_010278.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 1499323 5852783 APJL_1359 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative glycerol-3-phosphate acyltransferase PlsY YP_001652359.1 1498733 R 434271 CDS YP_001652360.1 165976767 5852679 1499395..1499748 1 NC_010278.1 dihydroneopterin aldolase 1499748 folB 5852679 folB Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydroneopterin aldolase YP_001652360.1 1499395 D 434271 CDS YP_001652361.1 165976768 5852296 1499857..1500750 1 NC_010278.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1500750 cdd 5852296 cdd Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytidine deaminase YP_001652361.1 1499857 D 434271 CDS YP_001652362.1 165976769 5852810 complement(1500797..1501735) 1 NC_010278.1 putative ABC transporter, membrane protein; cell division protein FtsX 1501735 ftsX 5852810 ftsX Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein FtsX YP_001652362.1 1500797 R 434271 CDS YP_001652363.1 165976770 5852808 complement(1501745..1502311) 1 NC_010278.1 cell division ATP-binding protein 1502311 fstE 5852808 fstE Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division ATP-binding protein YP_001652363.1 1501745 R 434271 CDS YP_001652364.1 165976771 5852805 complement(1502489..1504210) 1 NC_010278.1 cell division protein 1504210 ftsY 5852805 ftsY Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001652364.1 1502489 R 434271 CDS YP_001652365.1 165976772 5852788 1504288..1504881 1 NC_010278.1 putative methylase 1504881 5852788 APJL_1365 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative methylase YP_001652365.1 1504288 D 434271 CDS YP_001652366.1 165976773 5852817 1504946..1505257 1 NC_010278.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1505257 5852817 APJL_1366 Actinobacillus pleuropneumoniae serovar 3 str. JL03 dsDNA-mimic protein YP_001652366.1 1504946 D 434271 CDS YP_001652367.1 165976774 5852853 1505273..1505785 1 NC_010278.1 4-hydroxyphenylacetic acid hydroxylase 1505785 hpaC 5852853 hpaC Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-hydroxyphenylacetic acid hydroxylase YP_001652367.1 1505273 D 434271 CDS YP_001652368.1 165976775 5851013 1505900..1506772 1 NC_010278.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1506772 tehB 5851013 tehB Actinobacillus pleuropneumoniae serovar 3 str. JL03 tellurite resistance protein TehB YP_001652368.1 1505900 D 434271 CDS YP_001652369.1 165976776 5851459 complement(1506900..1507583) 1 NC_010278.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 1507583 artM 5851459 artM Actinobacillus pleuropneumoniae serovar 3 str. JL03 arginine transporter permease subunit ArtM YP_001652369.1 1506900 R 434271 CDS YP_001652370.1 165976777 5851664 complement(1507583..1508254) 1 NC_010278.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 1508254 artQ 5851664 artQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 arginine transporter permease subunit ArtQ YP_001652370.1 1507583 R 434271 CDS YP_001652371.1 165976778 5852828 complement(1508260..1508979) 1 NC_010278.1 amino acid ABC transporter periplasmic protein 1508979 artI 5852828 artI Actinobacillus pleuropneumoniae serovar 3 str. JL03 amino acid ABC transporter periplasmic protein YP_001652371.1 1508260 R 434271 CDS YP_001652372.1 165976779 5851363 complement(1508999..1509733) 1 NC_010278.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 1509733 artP 5851363 artP Actinobacillus pleuropneumoniae serovar 3 str. JL03 arginine transporter ATP-binding subunit YP_001652372.1 1508999 R 434271 CDS YP_001652373.1 165976780 5851048 complement(1509958..1510455) 1 NC_010278.1 phospholipid-binding protein 1510455 5851048 APJL_1373 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phospholipid-binding protein YP_001652373.1 1509958 R 434271 CDS YP_001652374.1 165976781 5851621 1510528..1511490 1 NC_010278.1 putative sodium/calcium exchange protein 1511490 5851621 APJL_1374 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sodium/calcium exchange protein YP_001652374.1 1510528 D 434271 CDS YP_001652375.1 165976782 5851329 complement(1511568..1511861) 1 NC_010278.1 transcriptional regulator 1511861 5851329 APJL_1375 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652375.1 1511568 R 434271 CDS YP_001652376.1 165976783 5851953 complement(1511842..1512213) 1 NC_010278.1 hypothetical protein 1512213 5851953 APJL_1376 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652376.1 1511842 R 434271 CDS YP_001652377.1 165976784 5851708 1512443..1514158 1 NC_010278.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 1514158 dipZ 5851708 dipZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol:disulfide interchange protein YP_001652377.1 1512443 D 434271 CDS YP_001652378.1 165976785 5851616 1514216..1514785 1 NC_010278.1 hypothetical protein 1514785 5851616 APJL_1378 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652378.1 1514216 D 434271 CDS YP_001652379.1 165976786 5851067 complement(1514829..1515683) 1 NC_010278.1 hypothetical protein 1515683 5851067 APJL_1379 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652379.1 1514829 R 434271 CDS YP_001652380.1 165976787 5851656 1515756..1517504 1 NC_010278.1 hypothetical protein 1517504 5851656 APJL_1380 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652380.1 1515756 D 434271 CDS YP_001652381.1 165976788 5851328 1517479..1517850 1 NC_010278.1 hypothetical protein 1517850 5851328 APJL_1381 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652381.1 1517479 D 434271 CDS YP_001652382.1 165976789 5850758 1517859..1518437 1 NC_010278.1 phosphoheptose isomerase 1518437 5850758 APJL_1382 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoheptose isomerase YP_001652382.1 1517859 D 434271 CDS YP_001652383.1 165976790 5851684 1518459..1519046 1 NC_010278.1 hypothetical protein 1519046 5851684 APJL_1383 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652383.1 1518459 D 434271 CDS YP_001652384.1 165976791 5852611 complement(1519258..1520565) 1 NC_010278.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 1520565 5852611 APJL_1384 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transglycosylase YP_001652384.1 1519258 R 434271 CDS YP_001652385.1 165976792 5851341 complement(1521496..1523445) 1 NC_010278.1 cytochrome c-type biogenesis protein 1523445 ccmF 5851341 ccmF Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c-type biogenesis protein YP_001652385.1 1521496 R 434271 CDS YP_001652386.1 165976793 5851641 complement(1523445..1523990) 1 NC_010278.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 1523990 ccmE 5851641 ccmE Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c-type biogenesis protein CcmE YP_001652386.1 1523445 R 434271 CDS YP_001652387.1 165976794 5850869 complement(1524174..1524371) 1 NC_010278.1 heme exporter protein D 1524371 ccmD 5850869 ccmD Actinobacillus pleuropneumoniae serovar 3 str. JL03 heme exporter protein D YP_001652387.1 1524174 R 434271 CDS YP_001652388.1 165976795 5850873 complement(1524384..1525115) 1 NC_010278.1 cytochrome c-type biogenesis protein 1525115 ccmC 5850873 ccmC Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c-type biogenesis protein YP_001652388.1 1524384 R 434271 CDS YP_001652389.1 165976796 5850750 complement(1525166..1525828) 1 NC_010278.1 cytochrome c-type biogenesis protein 1525828 ccmB 5850750 ccmB Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c-type biogenesis protein YP_001652389.1 1525166 R 434271 CDS YP_001652390.1 165976797 5850759 complement(1525825..1526460) 1 NC_010278.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1526460 ccmA2 5850759 ccmA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c biogenesis protein CcmA YP_001652390.1 1525825 R 434271 CDS YP_001652391.1 165976798 5851142 complement(1526601..1527311) 1 NC_010278.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 1527311 yfgE 5851142 yfgE Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA replication initiation factor YP_001652391.1 1526601 R 434271 CDS YP_001652392.1 165976799 5851242 1533305..1534138 1 NC_010278.1 hypothetical protein 1534138 5851242 APJL_1392 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652392.1 1533305 D 434271 CDS YP_001652393.1 165976800 5851623 1534313..1534579 1 NC_010278.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide; oxaloacetate decarboxylase subunit gamma 1534579 5851623 APJL_1393 Actinobacillus pleuropneumoniae serovar 3 str. JL03 oxaloacetate decarboxylase subunit gamma YP_001652393.1 1534313 D 434271 CDS YP_001652394.1 165976801 5850860 1534595..1536397 1 NC_010278.1 catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 1536397 oadA 5850860 oadA Actinobacillus pleuropneumoniae serovar 3 str. JL03 oxaloacetate decarboxylase YP_001652394.1 1534595 D 434271 CDS YP_001652395.1 165976802 5850851 1536414..1537718 1 NC_010278.1 oxaloacetate decarboxylase subunit beta 1537718 oadB 5850851 oadB Actinobacillus pleuropneumoniae serovar 3 str. JL03 oxaloacetate decarboxylase subunit beta YP_001652395.1 1536414 D 434271 CDS YP_001652396.1 165976803 5851057 1537851..1538174 1 NC_010278.1 alkylphosphonate uptake protein 1538174 phnA 5851057 phnA Actinobacillus pleuropneumoniae serovar 3 str. JL03 alkylphosphonate uptake protein YP_001652396.1 1537851 D 434271 CDS YP_001652397.1 165976804 5851007 1538346..1539746 1 NC_010278.1 cytochrome c peroxidase 1539746 mauG 5851007 mauG Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c peroxidase YP_001652397.1 1538346 D 434271 CDS YP_001652398.1 165976805 5850890 complement(1539812..1540108) 1 NC_010278.1 hypothetical protein 1540108 5850890 APJL_1398 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652398.1 1539812 R 434271 CDS YP_001652399.1 165976806 5851049 complement(1540110..1540643) 1 NC_010278.1 integral membrane protein 1540643 5851049 APJL_1399 Actinobacillus pleuropneumoniae serovar 3 str. JL03 integral membrane protein YP_001652399.1 1540110 R 434271 CDS YP_001652400.1 165976807 5850774 complement(1540765..1541106) 1 NC_010278.1 hypothetical protein 1541106 5850774 APJL_1400 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652400.1 1540765 R 434271 CDS YP_001652401.1 165976808 5851287 complement(1541162..1541914) 1 NC_010278.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1541914 trmB 5851287 trmB Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA (guanine-N(7)-)-methyltransferase YP_001652401.1 1541162 R 434271 CDS YP_001652402.1 165976809 5850786 complement(1541962..1542912) 1 NC_010278.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1542912 fabH 5850786 fabH Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-oxoacyl-ACP synthase YP_001652402.1 1541962 R 434271 CDS YP_001652403.1 165976810 5850796 complement(1542924..1543958) 1 NC_010278.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1543958 plsX 5850796 plsX Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative glycerol-3-phosphate acyltransferase PlsX YP_001652403.1 1542924 R 434271 CDS YP_001652404.1 165976811 5850734 complement(1543983..1544153) 1 NC_010278.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1544153 rpmF 5850734 rpmF Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L32 YP_001652404.1 1543983 R 434271 CDS YP_001652405.1 165976812 5850852 complement(1544171..1544695) 1 NC_010278.1 hypothetical protein 1544695 5850852 APJL_1405 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652405.1 1544171 R 434271 CDS YP_001652406.1 165976813 5850893 1544915..1545706 1 NC_010278.1 inner membrane protein 1545706 5850893 APJL_1406 Actinobacillus pleuropneumoniae serovar 3 str. JL03 inner membrane protein YP_001652406.1 1544915 D 434271 CDS YP_001652407.1 165976814 5851240 1545802..1547064 1 NC_010278.1 hypothetical protein 1547064 5851240 APJL_1407 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652407.1 1545802 D 434271 CDS YP_001652408.1 165976815 5850897 1547443..1548957 1 NC_010278.1 SNF family Na(+)-dependent transporter 1548957 5850897 APJL_1408 Actinobacillus pleuropneumoniae serovar 3 str. JL03 SNF family Na(+)-dependent transporter YP_001652408.1 1547443 D 434271 CDS YP_001652409.1 165976816 5851103 1548968..1549060 1 NC_010278.1 hypothetical protein 1549060 5851103 APJL_1409 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652409.1 1548968 D 434271 CDS YP_001652410.1 165976817 5851040 1549344..1550315 1 NC_010278.1 phosphotransferase system enzyme II,mannose-specific, factor IIAB 1550315 5851040 APJL_1410 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphotransferase system enzyme II,mannose-specific, factor IIAB YP_001652410.1 1549344 D 434271 CDS YP_001652411.1 165976818 5851302 1550328..1551128 1 NC_010278.1 PTS system mannose-specific transporter subunit IIC 1551128 5851302 APJL_1411 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system mannose-specific transporter subunit IIC YP_001652411.1 1550328 D 434271 CDS YP_001652412.1 165976819 5851008 1551142..1551978 1 NC_010278.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1551978 5851008 APJL_1412 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system mannose-specific transporter subunit IID YP_001652412.1 1551142 D 434271 CDS YP_001652413.1 165976820 5850950 1552077..1552535 1 NC_010278.1 hypothetical protein 1552535 5850950 APJL_1413 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652413.1 1552077 D 434271 CDS YP_001652414.1 165976821 5851254 1552532..1553737 1 NC_010278.1 mannose-6-phosphate isomerase 1553737 manA 5851254 manA Actinobacillus pleuropneumoniae serovar 3 str. JL03 mannose-6-phosphate isomerase YP_001652414.1 1552532 D 434271 CDS YP_001652415.1 165976822 5851027 1553799..1554311 1 NC_010278.1 hypothetical protein 1554311 5851027 APJL_1415 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652415.1 1553799 D 434271 CDS YP_001652416.1 165976823 5851074 1554557..1555597 1 NC_010278.1 AfuA protein 1555597 afuA1 5851074 afuA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 AfuA protein YP_001652416.1 1554557 D 434271 CDS YP_001652417.1 165976824 5851080 1555703..1557766 1 NC_010278.1 ABC-type thiamine transport system permease 1557766 afuB1 5851080 afuB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC-type thiamine transport system permease YP_001652417.1 1555703 D 434271 CDS YP_001652418.1 165976825 5851100 1557792..1558859 1 NC_010278.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 1558859 fbpC 5851100 fbpC Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferric transporter ATP-binding subunit YP_001652418.1 1557792 D 434271 CDS YP_001652419.1 165976826 5851117 complement(1558950..1560314) 1 NC_010278.1 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 1560314 mpl 5851117 mpl Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_001652419.1 1558950 R 434271 CDS YP_001652420.1 165976827 5850928 1560437..1561441 1 NC_010278.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1561441 fbp 5850928 fbp Actinobacillus pleuropneumoniae serovar 3 str. JL03 fructose-1,6-bisphosphatase YP_001652420.1 1560437 D 434271 CDS YP_001652421.1 165976828 5851123 complement(1561597..1562385) 1 NC_010278.1 hypothetical protein 1562385 5851123 APJL_1421 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652421.1 1561597 R 434271 CDS YP_001652422.1 165976829 5851143 complement(1562676..1563860) 1 NC_010278.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1563860 tufB1 5851143 tufB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 elongation factor Tu YP_001652422.1 1562676 R 434271 CDS YP_001652423.1 165976830 5850882 complement(1566128..1566598) 1 NC_010278.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1566598 rpsG 5850882 rpsG Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S7 YP_001652423.1 1566128 R 434271 CDS YP_001652424.1 165976831 5850777 complement(1566735..1567109) 1 NC_010278.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1567109 rpsL 5850777 rpsL Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S12 YP_001652424.1 1566735 R 434271 CDS YP_001652425.1 165976832 5850790 complement(1567231..1568190) 1 NC_010278.1 ADP-heptose--LPS heptosyltransferase 1568190 rfaC 5850790 rfaC Actinobacillus pleuropneumoniae serovar 3 str. JL03 ADP-heptose--LPS heptosyltransferase YP_001652425.1 1567231 R 434271 CDS YP_001652426.1 165976833 5850871 complement(1568265..1569302) 1 NC_010278.1 ADP-heptose LPS heptosyltransferase 1569302 rfaF 5850871 rfaF Actinobacillus pleuropneumoniae serovar 3 str. JL03 ADP-heptose LPS heptosyltransferase YP_001652426.1 1568265 R 434271 CDS YP_001652427.1 165976834 5850889 complement(1569384..1569836) 1 NC_010278.1 hypothetical protein 1569836 5850889 APJL_1429 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652427.1 1569384 R 434271 CDS YP_001652428.1 165976835 5851661 complement(1569910..1571301) 1 NC_010278.1 opacity associated protein A 1571301 oapA 5851661 oapA Actinobacillus pleuropneumoniae serovar 3 str. JL03 opacity associated protein A YP_001652428.1 1569910 R 434271 CDS YP_001652429.1 165976836 5851354 1571602..1571946 1 NC_010278.1 DNA uptake protein and related DNA-binding protein 1571946 5851354 APJL_1431 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA uptake protein and related DNA-binding protein YP_001652429.1 1571602 D 434271 CDS YP_001652430.1 165976837 5851387 1572097..1572987 1 NC_010278.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 1572987 psd 5851387 psd Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphatidylserine decarboxylase YP_001652430.1 1572097 D 434271 CDS YP_001652431.1 165976838 5850875 1573104..1575446 1 NC_010278.1 Type I restriction enzyme EcoEI R protein 1575446 5850875 APJL_1433 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Type I restriction enzyme EcoEI R protein YP_001652431.1 1573104 D 434271 CDS YP_001652432.1 165976839 5851238 1575530..1576999 1 NC_010278.1 Type I restriction-modification system M subunit 1576999 hsdM 5851238 hsdM Actinobacillus pleuropneumoniae serovar 3 str. JL03 Type I restriction-modification system M subunit YP_001652432.1 1575530 D 434271 CDS YP_001652433.1 165976840 5851122 1577008..1578003 1 NC_010278.1 putative DNA binding protein 1578003 5851122 APJL_1435 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative DNA binding protein YP_001652433.1 1577008 D 434271 CDS YP_001652434.1 165976841 5851197 1578057..1579469 1 NC_010278.1 Type I restriction enzyme EcoAI specificity protein 1579469 5851197 APJL_1436 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Type I restriction enzyme EcoAI specificity protein YP_001652434.1 1578057 D 434271 CDS YP_001652435.1 165976842 5851183 1579521..1580321 1 NC_010278.1 integrase 1580321 5851183 APJL_1437 Actinobacillus pleuropneumoniae serovar 3 str. JL03 integrase YP_001652435.1 1579521 D 434271 CDS YP_001652436.1 165976843 5851189 complement(1580364..1581584) 1 NC_010278.1 Type I restriction-modification system S subunit 1581584 5851189 APJL_1438 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Type I restriction-modification system S subunit YP_001652436.1 1580364 R 434271 CDS YP_001652437.1 165976844 5851148 1581826..1584099 1 NC_010278.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1584099 gshA 5851148 gshA Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional glutamate--cysteine ligase/glutathione synthetase YP_001652437.1 1581826 D 434271 CDS YP_001652438.1 165976845 5850891 complement(1584191..1584811) 1 NC_010278.1 CueR-like transcriptional regulator 1584811 5850891 APJL_1440 Actinobacillus pleuropneumoniae serovar 3 str. JL03 CueR-like transcriptional regulator YP_001652438.1 1584191 R 434271 CDS YP_001652439.1 165976846 5851081 1585077..1586213 1 NC_010278.1 tryptophan-specific transport protein 1586213 tnaB 5851081 tnaB Actinobacillus pleuropneumoniae serovar 3 str. JL03 tryptophan-specific transport protein YP_001652439.1 1585077 D 434271 CDS YP_001652440.1 165976847 5850998 complement(1586278..1586571) 1 NC_010278.1 hypothetical protein 1586571 5850998 APJL_1442 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652440.1 1586278 R 434271 CDS YP_001652441.1 165976848 5850866 complement(1587671..1589446) 1 NC_010278.1 long-chain acyl-CoA synthetase 1589446 fAA1 5850866 fAA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 long-chain acyl-CoA synthetase YP_001652441.1 1587671 R 434271 CDS YP_001652442.1 165976849 5850911 complement(1589627..1591102) 1 NC_010278.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1591102 mqo 5850911 mqo Actinobacillus pleuropneumoniae serovar 3 str. JL03 malate:quinone oxidoreductase YP_001652442.1 1589627 R 434271 CDS YP_001652443.1 165976850 5850728 complement(1591210..1591623) 1 NC_010278.1 hypothetical protein 1591623 5850728 APJL_1447 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652443.1 1591210 R 434271 CDS YP_001652444.1 165976851 5851023 1591843..1592184 1 NC_010278.1 hypothetical protein 1592184 5851023 APJL_1448 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652444.1 1591843 D 434271 CDS YP_001652445.1 165976852 5851310 1592226..1592651 1 NC_010278.1 hypothetical protein 1592651 5851310 APJL_1449 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652445.1 1592226 D 434271 CDS YP_001652446.1 165976853 5850927 complement(1592722..1593735) 1 NC_010278.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 1593735 mglC 5850927 mglC Actinobacillus pleuropneumoniae serovar 3 str. JL03 beta-methylgalactoside transporter inner membrane protein YP_001652446.1 1592722 R 434271 CDS YP_001652447.1 165976854 5851167 complement(1593752..1595251) 1 NC_010278.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 1595251 mglA 5851167 mglA Actinobacillus pleuropneumoniae serovar 3 str. JL03 galactose/methyl galaxtoside transporter ATP-binding protein YP_001652447.1 1593752 R 434271 CDS YP_001652448.1 165976855 5851177 complement(1595314..1596306) 1 NC_010278.1 periplasmic sugar-binding protein 1596306 rbsB1 5851177 rbsB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 periplasmic sugar-binding protein YP_001652448.1 1595314 R 434271 CDS YP_001652449.1 165976856 5850797 complement(1596560..1597666) 1 NC_010278.1 major outer membrane protein 1597666 momP1 5850797 momP1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 major outer membrane protein YP_001652449.1 1596560 R 434271 CDS YP_001652450.1 165976857 5850740 1598094..1601183 1 NC_010278.1 hypothetical protein 1601183 5850740 APJL_1454 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652450.1 1598094 D 434271 CDS YP_001652451.1 165976858 5850733 1601316..1601741 1 NC_010278.1 hypothetical protein 1601741 5850733 APJL_1455 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652451.1 1601316 D 434271 CDS YP_001652452.1 165976859 5850727 1601895..1603523 1 NC_010278.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 1603523 yidC 5850727 yidC Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative inner membrane protein translocase component YidC YP_001652452.1 1601895 D 434271 CDS YP_001652453.1 165976860 5850952 complement(1603808..1604422) 1 NC_010278.1 nitrate/TMAO reductase, membrane-bound tetraheme cytochrome c subunit 1604422 napC 5850952 napC Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitrate/TMAO reductase, membrane-bound tetraheme cytochrome c subunit YP_001652453.1 1603808 R 434271 CDS YP_001652454.1 165976861 5851075 complement(1604434..1604856) 1 NC_010278.1 nitrate reductase cytochrome c-type subunit 1604856 napB 5851075 napB Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitrate reductase cytochrome c-type subunit YP_001652454.1 1604434 R 434271 CDS YP_001652455.1 165976862 5850815 complement(1604875..1605768) 1 NC_010278.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 1605768 napH 5850815 napH Actinobacillus pleuropneumoniae serovar 3 str. JL03 quinol dehydrogenase membrane component YP_001652455.1 1604875 R 434271 CDS YP_001652456.1 165976863 5850896 complement(1605768..1606673) 1 NC_010278.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 1606673 napG 5850896 napG Actinobacillus pleuropneumoniae serovar 3 str. JL03 quinol dehydrogenase periplasmic component YP_001652456.1 1605768 R 434271 CDS YP_001652457.1 165976864 5850761 complement(1606808..1609291) 1 NC_010278.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 1609291 napA 5850761 napA Actinobacillus pleuropneumoniae serovar 3 str. JL03 nitrate reductase catalytic subunit YP_001652457.1 1606808 R 434271 CDS YP_001652458.1 165976865 5851200 complement(1609323..1609592) 1 NC_010278.1 periplasmic nitrate reductase subunit NapD 1609592 napD 5851200 napD Actinobacillus pleuropneumoniae serovar 3 str. JL03 periplasmic nitrate reductase subunit NapD YP_001652458.1 1609323 R 434271 CDS YP_001652459.1 165976866 5851192 complement(1609595..1610125) 1 NC_010278.1 ferredoxin-type protein 1610125 napF 5851192 napF Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferredoxin-type protein YP_001652459.1 1609595 R 434271 CDS YP_001652460.1 165976867 5851056 1610324..1610899 1 NC_010278.1 putative NAD(P)H oxidoreductase 1610899 5851056 APJL_1464 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative NAD(P)H oxidoreductase YP_001652460.1 1610324 D 434271 CDS YP_001652461.1 165976868 5851098 complement(1611053..1611853) 1 NC_010278.1 transposase 1611853 5851098 APJL_1465 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001652461.1 1611053 R 434271 CDS YP_001652462.1 165976869 5851034 complement(1611859..1612368) 1 NC_010278.1 transposase and inactivated derivative 1612368 5851034 APJL_1466 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001652462.1 1611859 R 434271 CDS YP_001652463.1 165976870 5850836 complement(1612472..1612984) 1 NC_010278.1 hypothetical protein 1612984 5850836 APJL_1467 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652463.1 1612472 R 434271 CDS YP_001652464.1 165976871 5851136 complement(1613145..1616132) 1 NC_010278.1 ribonuclease E 1616132 rne 5851136 rne Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease E YP_001652464.1 1613145 R 434271 CDS YP_001652465.1 165976872 5850802 1616602..1617609 1 NC_010278.1 hypothetical protein 1617609 5850802 APJL_1469 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652465.1 1616602 D 434271 CDS YP_001652466.1 165976873 5851144 complement(1617679..1618200) 1 NC_010278.1 hypothetical protein 1618200 5851144 APJL_1470 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652466.1 1617679 R 434271 CDS YP_001652467.1 165976874 5851121 complement(1618350..1619813) 1 NC_010278.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1619813 ubiD 5851121 ubiD Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001652467.1 1618350 R 434271 CDS YP_001652468.1 165976875 5850850 1619959..1620936 1 NC_010278.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1620936 znuA 5850850 znuA Actinobacillus pleuropneumoniae serovar 3 str. JL03 high-affinity zinc transporter periplasmic protein YP_001652468.1 1619959 D 434271 CDS YP_001652469.1 165976876 5851606 complement(1621035..1621823) 1 NC_010278.1 hypothetical protein 1621823 5851606 APJL_1473 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652469.1 1621035 R 434271 CDS YP_001652470.1 165976877 5850985 complement(1622110..1623339) 1 NC_010278.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1623339 serA 5850985 serA Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-3-phosphoglycerate dehydrogenase YP_001652470.1 1622110 R 434271 CDS YP_001652471.1 165976878 5851296 complement(1623483..1624142) 1 NC_010278.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1624142 rpiA 5851296 rpiA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribose-5-phosphate isomerase A YP_001652471.1 1623483 R 434271 CDS YP_001652472.1 165976879 5850766 complement(1624289..1625623) 1 NC_010278.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1625623 glmM 5850766 glmM Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoglucosamine mutase YP_001652472.1 1624289 R 434271 CDS YP_001652473.1 165976880 5850732 complement(1625695..1627221) 1 NC_010278.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 1627221 ilvA 5850732 ilvA Actinobacillus pleuropneumoniae serovar 3 str. JL03 threonine dehydratase YP_001652473.1 1625695 R 434271 CDS YP_001652474.1 165976881 5850719 complement(1627347..1627940) 1 NC_010278.1 FkbP-type peptidyl-prolyl cis-trans isomerase 1627940 slyD 5850719 slyD Actinobacillus pleuropneumoniae serovar 3 str. JL03 FkbP-type peptidyl-prolyl cis-trans isomerase YP_001652474.1 1627347 R 434271 CDS YP_001652475.1 165976882 5851651 complement(1628289..1628975) 1 NC_010278.1 aquaporin Z, transmembrane water channel 1628975 aqpZ 5851651 aqpZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 aquaporin Z, transmembrane water channel YP_001652475.1 1628289 R 434271 CDS YP_001652476.1 165976883 5851011 complement(1629121..1629837) 1 NC_010278.1 periplasmic/secreted protein 1629837 5851011 APJL_1480 Actinobacillus pleuropneumoniae serovar 3 str. JL03 periplasmic/secreted protein YP_001652476.1 1629121 R 434271 CDS YP_001652477.1 165976884 5851309 complement(1629879..1630634) 1 NC_010278.1 hypothetical protein 1630634 5851309 APJL_1481 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652477.1 1629879 R 434271 CDS YP_001652478.1 165976885 5851029 1630779..1631699 1 NC_010278.1 hypothetical protein 1631699 5851029 APJL_1482 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652478.1 1630779 D 434271 CDS YP_001652479.1 165976886 5851009 1631699..1632607 1 NC_010278.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1632607 menA 5851009 menA Actinobacillus pleuropneumoniae serovar 3 str. JL03 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001652479.1 1631699 D 434271 CDS YP_001652480.1 165976887 5851300 complement(1632685..1633026) 1 NC_010278.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 1633026 5851300 APJL_1484 Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-sulfur cluster insertion protein ErpA YP_001652480.1 1632685 R 434271 CDS YP_001652481.1 165976888 5851140 1633173..1634285 1 NC_010278.1 Wzz-like protein 1634285 wzz 5851140 wzz Actinobacillus pleuropneumoniae serovar 3 str. JL03 Wzz-like protein YP_001652481.1 1633173 D 434271 CDS YP_001652482.1 165976889 5851261 1634336..1635091 1 NC_010278.1 lipopolysaccharide biosynthesis glycosyltransferase 1635091 rfaG 5851261 rfaG Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipopolysaccharide biosynthesis glycosyltransferase YP_001652482.1 1634336 D 434271 CDS YP_001652483.1 165976890 5851268 1635112..1636179 1 NC_010278.1 VI polysaccharide biosynthesis protein 1636179 5851268 APJL_1487 Actinobacillus pleuropneumoniae serovar 3 str. JL03 VI polysaccharide biosynthesis protein YP_001652483.1 1635112 D 434271 CDS YP_001652484.1 165976891 5851264 1636188..1637240 1 NC_010278.1 glycosyltransferase 1637240 5851264 APJL_1488 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycosyltransferase YP_001652484.1 1636188 D 434271 CDS YP_001652485.1 165976892 5851519 1637257..1638306 1 NC_010278.1 hypothetical protein 1638306 5851519 APJL_1489 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652485.1 1637257 D 434271 CDS YP_001652486.1 165976893 5851252 1638309..1639640 1 NC_010278.1 oligosaccharide repeat-containing polymerase 1639640 wzy 5851252 wzy Actinobacillus pleuropneumoniae serovar 3 str. JL03 oligosaccharide repeat-containing polymerase YP_001652486.1 1638309 D 434271 CDS YP_001652487.1 165976894 5851246 1639637..1641088 1 NC_010278.1 flippase Wzx 1641088 wzx 5851246 wzx Actinobacillus pleuropneumoniae serovar 3 str. JL03 flippase Wzx YP_001652487.1 1639637 D 434271 CDS YP_001652488.1 165976895 5851233 1641131..1642228 1 NC_010278.1 UDP-galactopyranose mutase 1642228 glf 5851233 glf Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-galactopyranose mutase YP_001652488.1 1641131 D 434271 CDS YP_001652489.1 165976896 5851250 1642246..1643556 1 NC_010278.1 putative sugar transferase 1643556 5851250 APJL_1493 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sugar transferase YP_001652489.1 1642246 D 434271 CDS YP_001652490.1 165976897 5851243 1643560..1644039 1 NC_010278.1 acyltransferase 3 1644039 5851243 APJL_1494 Actinobacillus pleuropneumoniae serovar 3 str. JL03 acyltransferase 3 YP_001652490.1 1643560 D 434271 CDS YP_001652491.1 165976898 5851088 1644206..1644619 1 NC_010278.1 hypothetical protein 1644619 5851088 APJL_1495 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652491.1 1644206 D 434271 CDS YP_001652492.1 165976899 5851231 1644767..1645684 1 NC_010278.1 polysacchride biosynthesis protein 1645684 5851231 APJL_1496 Actinobacillus pleuropneumoniae serovar 3 str. JL03 polysacchride biosynthesis protein YP_001652492.1 1644767 D 434271 CDS YP_001652493.1 165976900 5851611 1645698..1646771 1 NC_010278.1 dTDP-glucose 4,6-dehydratase 1646771 rmlB 5851611 rmlB Actinobacillus pleuropneumoniae serovar 3 str. JL03 dTDP-glucose 4,6-dehydratase YP_001652493.1 1645698 D 434271 CDS YP_001652494.1 165976901 5851225 1647009..1647224 1 NC_010278.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1647224 rpsU 5851225 rpsU Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S21 YP_001652494.1 1647009 D 434271 CDS YP_001652495.1 165976902 5850969 1647401..1649143 1 NC_010278.1 synthesizes RNA primers at the replication forks; DNA primase 1649143 dnaG 5850969 dnaG Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA primase YP_001652495.1 1647401 D 434271 CDS YP_001652496.1 165976903 5851256 1649248..1651107 1 NC_010278.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1651107 rpoD 5851256 rpoD Actinobacillus pleuropneumoniae serovar 3 str. JL03 RNA polymerase sigma factor RpoD YP_001652496.1 1649248 D 434271 CDS YP_001652497.1 165976904 5851211 complement(1651260..1652450) 1 NC_010278.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1652450 tyrS 5851211 tyrS Actinobacillus pleuropneumoniae serovar 3 str. JL03 tyrosyl-tRNA synthetase YP_001652497.1 1651260 R 434271 CDS YP_001652498.1 165976905 5851194 complement(1652796..1653260) 1 NC_010278.1 hypothetical protein 1653260 5851194 APJL_1502 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652498.1 1652796 R 434271 CDS YP_001652499.1 165976906 5851193 complement(1653374..1655731) 1 NC_010278.1 ribonuclease R 1655731 5851193 APJL_1503 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease R YP_001652499.1 1653374 R 434271 CDS YP_001652500.1 165976907 5850881 complement(1655799..1656314) 1 NC_010278.1 thioredoxin-like protein 1656314 5850881 APJL_1504 Actinobacillus pleuropneumoniae serovar 3 str. JL03 thioredoxin-like protein YP_001652500.1 1655799 R 434271 CDS YP_001652501.1 165976908 5851185 complement(1656314..1656946) 1 NC_010278.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 1656946 5851185 APJL_1505 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding transcriptional repressor FabR YP_001652501.1 1656314 R 434271 CDS YP_001652502.1 165976909 5850962 complement(1656939..1657832) 1 NC_010278.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 1657832 oxyR 5850962 oxyR Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding transcriptional regulator OxyR YP_001652502.1 1656939 R 434271 CDS YP_001652503.1 165976910 5851184 1657958..1658692 1 NC_010278.1 hybrid peroxiredoxin hyPrx5 1658692 5851184 APJL_1507 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hybrid peroxiredoxin hyPrx5 YP_001652503.1 1657958 D 434271 CDS YP_001652504.1 165976911 5850868 1658920..1659708 1 NC_010278.1 hypothetical protein 1659708 5850868 APJL_1508 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652504.1 1658920 D 434271 CDS YP_001652505.1 165976912 5851180 complement(1659942..1660574) 1 NC_010278.1 hypothetical protein 1660574 5851180 APJL_1509 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652505.1 1659942 R 434271 CDS YP_001652506.1 165976913 5850963 complement(1660978..1661679) 1 NC_010278.1 pyridoxine kinase 1661679 pdxY 5850963 pdxY Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyridoxine kinase YP_001652506.1 1660978 R 434271 CDS YP_001652507.1 165976914 5851156 complement(1662142..1663095) 1 NC_010278.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1663095 accA 5851156 accA Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001652507.1 1662142 R 434271 CDS YP_001652508.1 165976915 5851004 complement(1663212..1664570) 1 NC_010278.1 SufI protein 1664570 sufI1 5851004 sufI1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 SufI protein YP_001652508.1 1663212 R 434271 CDS YP_001652509.1 165976916 5850909 complement(1664627..1665373) 1 NC_010278.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 1665373 plsC 5850909 plsC Actinobacillus pleuropneumoniae serovar 3 str. JL03 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001652509.1 1664627 R 434271 CDS YP_001652510.1 165976917 5851229 1665516..1666016 1 NC_010278.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1666016 tpx 5851229 tpx Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol peroxidase YP_001652510.1 1665516 D 434271 CDS YP_001652511.1 165976918 5850957 1666139..1667497 1 NC_010278.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1667497 trmE 5850957 trmE Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA modification GTPase TrmE YP_001652511.1 1666139 D 434271 CDS YP_001652512.1 165976919 5850879 complement(1667606..1668961) 1 NC_010278.1 hypothetical protein 1668961 5850879 APJL_1516 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652512.1 1667606 R 434271 CDS YP_001652513.1 165976920 5850785 complement(1668974..1669246) 1 NC_010278.1 ACT domain-containing protein; hypothetical protein 1669246 gcvR 5850785 gcvR Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652513.1 1668974 R 434271 CDS YP_001652514.1 165976921 5850979 complement(1669384..1670073) 1 NC_010278.1 pirin-related protein 1670073 5850979 APJL_1518 Actinobacillus pleuropneumoniae serovar 3 str. JL03 pirin-related protein YP_001652514.1 1669384 R 434271 CDS YP_001652515.1 165976922 5850935 1670389..1670958 1 NC_010278.1 fine tangled pili major subunit 1670958 ftpA 5850935 ftpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 fine tangled pili major subunit YP_001652515.1 1670389 D 434271 CDS YP_001652516.1 165976923 5851163 1671191..1671493 1 NC_010278.1 transcriptional regulator 1671493 5851163 APJL_1520 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652516.1 1671191 D 434271 CDS YP_001652517.1 165976924 5851096 1671640..1673004 1 NC_010278.1 hypothetical protein 1673004 5851096 APJL_1521 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652517.1 1671640 D 434271 CDS YP_001652518.1 165976925 5850737 complement(1673072..1675246) 1 NC_010278.1 hypothetical protein 1675246 5850737 APJL_1522 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652518.1 1673072 R 434271 CDS YP_001652519.1 165976926 5851030 complement(1675328..1675786) 1 NC_010278.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1675786 mgsA 5851030 mgsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 methylglyoxal synthase YP_001652519.1 1675328 R 434271 CDS YP_001652520.1 165976927 5850813 1675919..1677199 1 NC_010278.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1677199 thrC 5850813 thrC Actinobacillus pleuropneumoniae serovar 3 str. JL03 threonine synthase YP_001652520.1 1675919 D 434271 CDS YP_001652521.1 165976928 5851105 1677285..1677794 1 NC_010278.1 transposase and inactivated derivative 1677794 5851105 APJL_1525 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001652521.1 1677285 D 434271 CDS YP_001652522.1 165976929 5851083 1677800..1678618 1 NC_010278.1 transposase 1678618 5851083 APJL_1526 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001652522.1 1677800 D 434271 CDS YP_001652523.1 165976930 5850799 complement(1678677..1681541) 1 NC_010278.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1681541 valS 5850799 valS Actinobacillus pleuropneumoniae serovar 3 str. JL03 valyl-tRNA synthetase YP_001652523.1 1678677 R 434271 CDS YP_001652524.1 165976931 5850847 complement(1681556..1682032) 1 NC_010278.1 hypothetical protein 1682032 5850847 APJL_1528 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652524.1 1681556 R 434271 CDS YP_001652525.1 165976932 5850912 complement(1682284..1682460) 1 NC_010278.1 hypothetical protein 1682460 5850912 APJL_1529 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652525.1 1682284 R 434271 CDS YP_001652526.1 165976933 5851205 complement(1682620..1683042) 1 NC_010278.1 acetyltransferase 1683042 elaA 5851205 elaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyltransferase YP_001652526.1 1682620 R 434271 CDS YP_001652527.1 165976934 5850783 complement(1683043..1683480) 1 NC_010278.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 1683480 holC 5850783 holC Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunit chi YP_001652527.1 1683043 R 434271 CDS YP_001652528.1 165976935 5851971 1683754..1684197 1 NC_010278.1 LysM domain/BON superfamily protein 1684197 5851971 APJL_1532 Actinobacillus pleuropneumoniae serovar 3 str. JL03 LysM domain/BON superfamily protein YP_001652528.1 1683754 D 434271 CDS YP_001652529.1 165976936 5851732 1684399..1685700 1 NC_010278.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1685700 tig 5851732 tig Actinobacillus pleuropneumoniae serovar 3 str. JL03 trigger factor YP_001652529.1 1684399 D 434271 CDS YP_001652530.1 165976937 5851665 1685833..1686282 1 NC_010278.1 rhodanese-related sulfurtransferase 1686282 5851665 APJL_1534 Actinobacillus pleuropneumoniae serovar 3 str. JL03 rhodanese-related sulfurtransferase YP_001652530.1 1685833 D 434271 CDS YP_001652531.1 165976938 5851966 1686307..1686807 1 NC_010278.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1686807 secB 5851966 secB Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit SecB YP_001652531.1 1686307 D 434271 CDS YP_001652532.1 165976939 5851959 1686992..1688002 1 NC_010278.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1688002 gpsA 5851959 gpsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001652532.1 1686992 D 434271 CDS YP_001652533.1 165976940 5851702 1688014..1688829 1 NC_010278.1 catalyzes the O-acetylation of serine; serine acetyltransferase 1688829 cysE 5851702 cysE Actinobacillus pleuropneumoniae serovar 3 str. JL03 serine acetyltransferase YP_001652533.1 1688014 D 434271 CDS YP_001652534.1 165976941 5851358 complement(1689023..1690207) 1 NC_010278.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1690207 tufB2 5851358 tufB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 elongation factor Tu YP_001652534.1 1689023 R 434271 CDS YP_001652535.1 165976942 5851478 1690961..1691911 1 NC_010278.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1691911 coaA 5851478 coaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 pantothenate kinase YP_001652535.1 1690961 D 434271 CDS YP_001652536.1 165976943 5851094 1692046..1692588 1 NC_010278.1 thiol:disulfide interchange protein 1692588 dsbE1 5851094 dsbE1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol:disulfide interchange protein YP_001652536.1 1692046 D 434271 CDS YP_001652537.1 165976944 5851171 1692593..1693060 1 NC_010278.1 cytochrome C-type biogenesis protein 1693060 ccmH_1 5851171 ccmH_1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome C-type biogenesis protein YP_001652537.1 1692593 D 434271 CDS YP_001652538.1 165976945 5851251 1693060..1693974 1 NC_010278.1 cytochrome C-type biogenesis protein 1693974 ccmH_2 5851251 ccmH_2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome C-type biogenesis protein YP_001652538.1 1693060 D 434271 CDS YP_001652539.1 165976946 5851279 1694046..1694630 1 NC_010278.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 1694630 mogA 5851279 mogA Actinobacillus pleuropneumoniae serovar 3 str. JL03 molybdenum cofactor biosynthesis protein MogA YP_001652539.1 1694046 D 434271 CDS YP_001652540.1 165976947 5851228 1694750..1695088 1 NC_010278.1 putative nitrogen regulatory protein P-II 1695088 glnB 5851228 glnB Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative nitrogen regulatory protein P-II YP_001652540.1 1694750 D 434271 CDS YP_001652541.1 165976948 5851166 1695167..1695649 1 NC_010278.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1695649 lspA 5851166 lspA Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein signal peptidase YP_001652541.1 1695167 D 434271 CDS YP_001652542.1 165976949 5851054 1695650..1696594 1 NC_010278.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1696594 ispH 5851054 ispH Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001652542.1 1695650 D 434271 CDS YP_001652543.1 165976950 5851070 1696594..1696842 1 NC_010278.1 hypothetical protein 1696842 5851070 APJL_1547 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652543.1 1696594 D 434271 CDS YP_001652544.1 165976951 5850917 complement(1696911..1697510) 1 NC_010278.1 nucleoside-diphosphate-sugarepimerase 1697510 5850917 APJL_1548 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nucleoside-diphosphate-sugarepimerase YP_001652544.1 1696911 R 434271 CDS YP_001652545.1 165976952 5850819 complement(1697510..1699327) 1 NC_010278.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1699327 chuW 5850819 chuW Actinobacillus pleuropneumoniae serovar 3 str. JL03 coproporphyrinogen III oxidase YP_001652545.1 1697510 R 434271 CDS YP_001652546.1 165976953 5850966 complement(1699484..1700101) 1 NC_010278.1 glutathione S-transferase 1700101 gst 5850966 gst Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutathione S-transferase YP_001652546.1 1699484 R 434271 CDS YP_001652547.1 165976954 5850830 complement(1700167..1701417) 1 NC_010278.1 diaminopimelate decarboxylase 1701417 lysA 5850830 lysA Actinobacillus pleuropneumoniae serovar 3 str. JL03 diaminopimelate decarboxylase YP_001652547.1 1700167 R 434271 CDS YP_001652548.1 165976955 5850921 complement(1701540..1701653) 1 NC_010278.1 hypothetical protein 1701653 5850921 APJL_1552 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652548.1 1701540 R 434271 CDS YP_001652549.1 165976956 5850823 complement(1701831..1702175) 1 NC_010278.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 1702175 frdD 5850823 frdD Actinobacillus pleuropneumoniae serovar 3 str. JL03 fumarate reductase subunit D YP_001652549.1 1701831 R 434271 CDS YP_001652550.1 165976957 5850903 complement(1702188..1702580) 1 NC_010278.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 1702580 frdC 5850903 frdC Actinobacillus pleuropneumoniae serovar 3 str. JL03 fumarate reductase subunit C YP_001652550.1 1702188 R 434271 CDS YP_001652551.1 165976958 5850731 complement(1702589..1703323) 1 NC_010278.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 1703323 frdB 5850731 frdB Actinobacillus pleuropneumoniae serovar 3 str. JL03 fumarate reductase iron-sulfur subunit YP_001652551.1 1702589 R 434271 CDS YP_001652552.1 165976959 5850804 complement(1703336..1705135) 1 NC_010278.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 1705135 frdA 5850804 frdA Actinobacillus pleuropneumoniae serovar 3 str. JL03 fumarate reductase flavoprotein subunit YP_001652552.1 1703336 R 434271 CDS YP_001652553.1 165976960 5850946 1705478..1706461 1 NC_010278.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 1706461 genX 5850946 genX Actinobacillus pleuropneumoniae serovar 3 str. JL03 lysyl-tRNA synthetase YP_001652553.1 1705478 D 434271 CDS YP_001652554.1 165976961 5850751 complement(1706543..1707367) 1 NC_010278.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1707367 dapF 5850751 dapF Actinobacillus pleuropneumoniae serovar 3 str. JL03 diaminopimelate epimerase YP_001652554.1 1706543 R 434271 CDS YP_001652555.1 165976962 5851525 1707548..1708870 1 NC_010278.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 1708870 dcuB1 5851525 dcuB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 anaerobic C4-dicarboxylate transporter YP_001652555.1 1707548 D 434271 CDS YP_001652556.1 165976963 5851226 complement(1708942..1709313) 1 NC_010278.1 CrcB protein 1709313 crcB 5851226 crcB Actinobacillus pleuropneumoniae serovar 3 str. JL03 CrcB protein YP_001652556.1 1708942 R 434271 CDS YP_001652557.1 165976964 5851433 complement(1709316..1710380) 1 NC_010278.1 putative transport system permease 1710380 5851433 APJL_1561 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transport system permease YP_001652557.1 1709316 R 434271 CDS YP_001652558.1 165976965 5850738 1710475..1711584 1 NC_010278.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1711584 anmK 5850738 anmK Actinobacillus pleuropneumoniae serovar 3 str. JL03 anhydro-N-acetylmuramic acid kinase YP_001652558.1 1710475 D 434271 CDS YP_001652559.1 165976966 5850961 1711638..1712552 1 NC_010278.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 1712552 murQ 5850961 murQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetylmuramic acid 6-phosphate etherase YP_001652559.1 1711638 D 434271 CDS YP_001652560.1 165976967 5851432 complement(1712622..1713503) 1 NC_010278.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1713503 prmA 5851432 prmA Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L11 methyltransferase YP_001652560.1 1712622 R 434271 CDS YP_001652561.1 165976968 5851353 complement(1713587..1714054) 1 NC_010278.1 N-acetyltransferase GCN5 1714054 5851353 APJL_1565 Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetyltransferase GCN5 YP_001652561.1 1713587 R 434271 CDS YP_001652562.1 165976969 5851235 complement(1714058..1714318) 1 NC_010278.1 hypothetical protein 1714318 5851235 APJL_1566 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652562.1 1714058 R 434271 CDS YP_001652563.1 165976970 5850748 complement(1714439..1715899) 1 NC_010278.1 TldD protein 1715899 tldD 5850748 tldD Actinobacillus pleuropneumoniae serovar 3 str. JL03 TldD protein YP_001652563.1 1714439 R 434271 CDS YP_001652564.1 165976971 5850762 1716029..1717288 1 NC_010278.1 cell-cycle protein 1717288 mesJ 5850762 mesJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell-cycle protein YP_001652564.1 1716029 D 434271 CDS YP_001652565.1 165976972 5850745 complement(1717315..1717605) 1 NC_010278.1 hypothetical protein 1717605 5850745 APJL_1569 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652565.1 1717315 R 434271 CDS YP_001652566.1 165976973 5850718 complement(1717607..1718500) 1 NC_010278.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1718500 xerD 5850718 xerD Actinobacillus pleuropneumoniae serovar 3 str. JL03 site-specific tyrosine recombinase XerD YP_001652566.1 1717607 R 434271 CDS YP_001652567.1 165976974 5851895 complement(1724762..1725487) 1 NC_010278.1 putative UDP-N-acetyl-D-mannosaminuronic acid transferase 1725487 wecG 5851895 wecG Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative UDP-N-acetyl-D-mannosaminuronic acid transferase YP_001652567.1 1724762 R 434271 CDS YP_001652568.1 165976975 5851752 complement(1725471..1726805) 1 NC_010278.1 enterobacterial common antigen polymerase; putative common antigen polymerase 1726805 5851752 APJL_1572 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative common antigen polymerase YP_001652568.1 1725471 R 434271 CDS YP_001652569.1 165976976 5851912 complement(1726805..1727875) 1 NC_010278.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 1727875 wecF 5851912 wecF Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-alpha-L-fucosyltransferase YP_001652569.1 1726805 R 434271 CDS YP_001652570.1 165976977 5851901 1728155..1729810 1 NC_010278.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1729810 5851901 APJL_1574 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hydroxylamine reductase YP_001652570.1 1728155 D 434271 CDS YP_001652571.1 165976978 5851994 1729913..1730932 1 NC_010278.1 HCP oxidoreductase 1730932 5851994 APJL_1575 Actinobacillus pleuropneumoniae serovar 3 str. JL03 HCP oxidoreductase YP_001652571.1 1729913 D 434271 CDS YP_001652572.1 165976979 5851823 complement(1730974..1732224) 1 NC_010278.1 lipopolysaccharide biosynthesis protein 1732224 wzxE 5851823 wzxE Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipopolysaccharide biosynthesis protein YP_001652572.1 1730974 R 434271 CDS YP_001652573.1 165976980 5851788 complement(1732212..1733357) 1 NC_010278.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 1733357 rffA 5851788 rffA Actinobacillus pleuropneumoniae serovar 3 str. JL03 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_001652573.1 1732212 R 434271 CDS YP_001652574.1 165976981 5851893 complement(1733364..1733987) 1 NC_010278.1 TDP-fucosamine acetyltransferase 1733987 rffC 5851893 rffC Actinobacillus pleuropneumoniae serovar 3 str. JL03 TDP-fucosamine acetyltransferase YP_001652574.1 1733364 R 434271 CDS YP_001652575.1 165976982 5852028 complement(1733987..1735258) 1 NC_010278.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 1735258 wecC 5852028 wecC Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetyl-D-mannosamine dehydrogenase YP_001652575.1 1733987 R 434271 CDS YP_001652576.1 165976983 5851374 complement(1735337..1736473) 1 NC_010278.1 UDP-N-acetylglucosamine 2-epimerase 1736473 wecB 5851374 wecB Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetylglucosamine 2-epimerase YP_001652576.1 1735337 R 434271 CDS YP_001652577.1 165976984 5851050 complement(1736457..1737335) 1 NC_010278.1 putative transport protein 1737335 5851050 APJL_1581 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transport protein YP_001652577.1 1736457 R 434271 CDS YP_001652578.1 165976985 5851903 complement(1737370..1738443) 1 NC_010278.1 undecaprenyl-phosphatealpha-N- acetylglucosaminyltransferase 1738443 wecA 5851903 wecA Actinobacillus pleuropneumoniae serovar 3 str. JL03 undecaprenyl-phosphatealpha-N- acetylglucosaminyltransferase YP_001652578.1 1737370 R 434271 CDS YP_001652579.1 165976986 5851861 1738742..1740022 1 NC_010278.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1740022 hemL 5851861 hemL Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutamate-1-semialdehyde aminotransferase YP_001652579.1 1738742 D 434271 CDS YP_001652580.1 165976987 5851772 complement(1740077..1741144) 1 NC_010278.1 transport system permease 1741144 5851772 APJL_1584 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transport system permease YP_001652580.1 1740077 R 434271 CDS YP_001652581.1 165976988 5851343 complement(1741164..1742693) 1 NC_010278.1 MviN virulence factor 1742693 mviN 5851343 mviN Actinobacillus pleuropneumoniae serovar 3 str. JL03 MviN virulence factor YP_001652581.1 1741164 R 434271 CDS YP_001652582.1 165976989 5851699 1743127..1743390 1 NC_010278.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1743390 rpsT 5851699 rpsT Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S20 YP_001652582.1 1743127 D 434271 CDS YP_001652583.1 165976990 5852013 complement(1743447..1744823) 1 NC_010278.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1744823 trkA 5852013 trkA Actinobacillus pleuropneumoniae serovar 3 str. JL03 potassium transporter peripheral membrane protein YP_001652583.1 1743447 R 434271 CDS YP_001652584.1 165976991 5851848 complement(1744873..1746171) 1 NC_010278.1 SUN protein 1746171 sun 5851848 sun Actinobacillus pleuropneumoniae serovar 3 str. JL03 SUN protein YP_001652584.1 1744873 R 434271 CDS YP_001652585.1 165976992 5851395 complement(1746185..1748020) 1 NC_010278.1 selenocysteine-specific elongation factor 1748020 selB 5851395 selB Actinobacillus pleuropneumoniae serovar 3 str. JL03 selenocysteine-specific elongation factor YP_001652585.1 1746185 R 434271 CDS YP_001652586.1 165976993 5851807 complement(1748017..1749288) 1 NC_010278.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1749288 selA 5851807 selA Actinobacillus pleuropneumoniae serovar 3 str. JL03 selenocysteine synthase YP_001652586.1 1748017 R 434271 CDS YP_001652587.1 165976994 5850803 1749579..1750022 1 NC_010278.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1750022 mioC 5850803 mioC Actinobacillus pleuropneumoniae serovar 3 str. JL03 flavodoxin YP_001652587.1 1749579 D 434271 CDS YP_001652588.1 165976995 5851749 1750548..1750724 1 NC_010278.1 hypothetical protein 1750724 5851749 APJL_1592 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652588.1 1750548 D 434271 CDS YP_001652589.1 165976996 5851970 1750742..1750888 1 NC_010278.1 hypothetical protein 1750888 5851970 APJL_1593 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652589.1 1750742 D 434271 CDS YP_001652590.1 165976997 5851350 complement(1750860..1752317) 1 NC_010278.1 sugar (pentulose and hexulose) kinase 1752317 xylB1 5851350 xylB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sugar (pentulose and hexulose) kinase YP_001652590.1 1750860 R 434271 CDS YP_001652591.1 165976998 5851146 complement(1752332..1752727) 1 NC_010278.1 gluconolactonase 1752727 5851146 APJL_1595 Actinobacillus pleuropneumoniae serovar 3 str. JL03 gluconolactonase YP_001652591.1 1752332 R 434271 CDS YP_001652592.1 165976999 5851693 complement(1753150..1753350) 1 NC_010278.1 hypothetical protein 1753350 5851693 APJL_1596 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652592.1 1753150 R 434271 CDS YP_001652593.1 165977000 5851902 complement(1753826..1756621) 1 NC_010278.1 transferrin-binding protein 1 1756621 tbpA1 5851902 tbpA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transferrin-binding protein 1 YP_001652593.1 1753826 R 434271 CDS YP_001652594.1 165977001 5851927 complement(1756635..1758095) 1 NC_010278.1 transferrin-binding protein 2 1758095 tbpB1 5851927 tbpB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transferrin-binding protein 2 YP_001652594.1 1756635 R 434271 CDS YP_001652595.1 165977002 5851776 complement(1758306..1758716) 1 NC_010278.1 biopolymer transport ExbD protein 1758716 exbD1 5851776 exbD1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 biopolymer transport ExbD protein YP_001652595.1 1758306 R 434271 CDS YP_001652596.1 165977003 5851871 complement(1758716..1759384) 1 NC_010278.1 biopolymer transport ExbB protein 1759384 exbB1 5851871 exbB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 biopolymer transport ExbB protein YP_001652596.1 1758716 R 434271 CDS YP_001652597.1 165977004 5851873 complement(1759406..1760146) 1 NC_010278.1 hypothetical protein 1760146 tonB1 5851873 tonB1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652597.1 1759406 R 434271 CDS YP_001652598.1 165977005 5851998 complement(1760422..1760670) 1 NC_010278.1 hypothetical protein 1760670 5851998 APJL_1602 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652598.1 1760422 R 434271 CDS YP_001652599.1 165977006 5852023 complement(1760677..1760808) 1 NC_010278.1 hypothetical protein 1760808 5852023 APJL_1603 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652599.1 1760677 R 434271 CDS YP_001652600.1 165977007 5852019 complement(1760837..1761511) 1 NC_010278.1 malate/L-lactate dehydrogenase 1761511 5852019 APJL_1604 Actinobacillus pleuropneumoniae serovar 3 str. JL03 malate/L-lactate dehydrogenase YP_001652600.1 1760837 R 434271 CDS YP_001652601.1 165977008 5852015 complement(1761498..1761836) 1 NC_010278.1 malate/L-lactate dehydrogenase 1761836 5852015 APJL_1605 Actinobacillus pleuropneumoniae serovar 3 str. JL03 malate/L-lactate dehydrogenase YP_001652601.1 1761498 R 434271 CDS YP_001652602.1 165977009 5852005 1762065..1762607 1 NC_010278.1 alpha/beta hydrolase superfamily esterase 1762607 5852005 APJL_1606 Actinobacillus pleuropneumoniae serovar 3 str. JL03 alpha/beta hydrolase superfamily esterase YP_001652602.1 1762065 D 434271 CDS YP_001652603.1 165977010 5852002 complement(1762679..1763233) 1 NC_010278.1 hypothetical protein 1763233 5852002 APJL_1607 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652603.1 1762679 R 434271 CDS YP_001652604.1 165977011 5851755 complement(1763341..1764846) 1 NC_010278.1 hypothetical protein 1764846 5851755 APJL_1608 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652604.1 1763341 R 434271 CDS YP_001652605.1 165977012 5851220 complement(1764855..1765892) 1 NC_010278.1 hypothetical protein 1765892 5851220 APJL_1609 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652605.1 1764855 R 434271 CDS YP_001652606.1 165977013 5851942 complement(1765911..1767281) 1 NC_010278.1 hypothetical protein 1767281 5851942 APJL_1610 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652606.1 1765911 R 434271 CDS YP_001652607.1 165977014 5851675 complement(1767486..1769327) 1 NC_010278.1 teichoic acid biosynthesis protein 1769327 cps3D 5851675 cps3D Actinobacillus pleuropneumoniae serovar 3 str. JL03 teichoic acid biosynthesis protein YP_001652607.1 1767486 R 434271 CDS YP_001652608.1 165977015 5851951 complement(1769332..1770480) 1 NC_010278.1 Cps7C 1770480 cps3C 5851951 cps3C Actinobacillus pleuropneumoniae serovar 3 str. JL03 Cps7C YP_001652608.1 1769332 R 434271 CDS YP_001652609.1 165977016 5851850 complement(1770482..1770910) 1 NC_010278.1 glycerol-3-phosphate cytidylyltransferase 1770910 cps3B 5851850 cps3B Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerol-3-phosphate cytidylyltransferase YP_001652609.1 1770482 R 434271 CDS YP_001652610.1 165977017 5851674 complement(1770964..1772106) 1 NC_010278.1 Cps2A 1772106 cps3A 5851674 cps3A Actinobacillus pleuropneumoniae serovar 3 str. JL03 Cps2A YP_001652610.1 1770964 R 434271 CDS YP_001652611.1 165977018 5851863 1772285..1773472 1 NC_010278.1 HexD, capsule biosynthetic locus protein 1773472 cpxD 5851863 cpxD Actinobacillus pleuropneumoniae serovar 3 str. JL03 HexD, capsule biosynthetic locus protein YP_001652611.1 1772285 D 434271 CDS YP_001652612.1 165977019 5851954 1773498..1774655 1 NC_010278.1 capsule polysaccharide export transport system permease 1774655 cpxC 5851954 cpxC Actinobacillus pleuropneumoniae serovar 3 str. JL03 capsule polysaccharide export transport system permease YP_001652612.1 1773498 D 434271 CDS YP_001652613.1 165977020 5851869 1774727..1775452 1 NC_010278.1 capsule polysaccharide export transport system permease 1775452 cpxB 5851869 cpxB Actinobacillus pleuropneumoniae serovar 3 str. JL03 capsule polysaccharide export transport system permease YP_001652613.1 1774727 D 434271 CDS YP_001652614.1 165977021 5851984 1775449..1776099 1 NC_010278.1 capsule polysaccharide export transport system ATP-binding protein 1776099 cpxA 5851984 cpxA Actinobacillus pleuropneumoniae serovar 3 str. JL03 capsule polysaccharide export transport system ATP-binding protein YP_001652614.1 1775449 D 434271 CDS YP_001652615.1 165977022 5851775 complement(1776298..1777755) 1 NC_010278.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF 1777755 modF 5851775 modF Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative molybdenum transport ATP-binding protein ModF YP_001652615.1 1776298 R 434271 CDS YP_001652616.1 165977023 5851676 complement(1777848..1778798) 1 NC_010278.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1778798 fmt 5851676 fmt Actinobacillus pleuropneumoniae serovar 3 str. JL03 methionyl-tRNA formyltransferase YP_001652616.1 1777848 R 434271 CDS YP_001652617.1 165977024 5851622 complement(1778961..1779911) 1 NC_010278.1 putative immunogenic protein 1779911 5851622 APJL_1621 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative immunogenic protein YP_001652617.1 1778961 R 434271 CDS YP_001652618.1 165977025 5852049 1779946..1780689 1 NC_010278.1 hypothetical protein 1780689 5852049 APJL_1622 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652618.1 1779946 D 434271 CDS YP_001652619.1 165977026 5852044 1780770..1782248 1 NC_010278.1 trk-type K+ transport system, membrane component 1782248 trkG 5852044 trkG Actinobacillus pleuropneumoniae serovar 3 str. JL03 trk-type K+ transport system, membrane component YP_001652619.1 1780770 D 434271 CDS YP_001652620.1 165977027 5852068 1782263..1782790 1 NC_010278.1 flavodoxin 1782790 5852068 APJL_1624 Actinobacillus pleuropneumoniae serovar 3 str. JL03 flavodoxin YP_001652620.1 1782263 D 434271 CDS YP_001652621.1 165977028 5852074 1782894..1783283 1 NC_010278.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 1783283 mscL 5852074 mscL Actinobacillus pleuropneumoniae serovar 3 str. JL03 large-conductance mechanosensitive channel YP_001652621.1 1782894 D 434271 CDS YP_001652622.1 165977029 5852103 complement(1783413..1784405) 1 NC_010278.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1784405 lipA1 5852103 lipA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoyl synthase YP_001652622.1 1783413 R 434271 CDS YP_001652623.1 165977030 5852823 complement(1784470..1785162) 1 NC_010278.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1785162 lipB 5852823 lipB Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoate-protein ligase B YP_001652623.1 1784470 R 434271 CDS YP_001652624.1 165977031 5852659 complement(1785194..1785493) 1 NC_010278.1 hypothetical protein 1785493 5852659 APJL_1628 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652624.1 1785194 R 434271 CDS YP_001652625.1 165977032 5852222 complement(1785627..1786805) 1 NC_010278.1 penicillin-binding protein 5 1786805 dacA 5852222 dacA Actinobacillus pleuropneumoniae serovar 3 str. JL03 penicillin-binding protein 5 YP_001652625.1 1785627 R 434271 CDS YP_001652626.1 165977033 5852355 complement(1786901..1787464) 1 NC_010278.1 rare lipoprotein A 1787464 5852355 APJL_1630 Actinobacillus pleuropneumoniae serovar 3 str. JL03 rare lipoprotein A YP_001652626.1 1786901 R 434271 CDS YP_001652627.1 165977034 5852225 complement(1787639..1788763) 1 NC_010278.1 rod-shape-determining protein RodA 1788763 mrdB 5852225 mrdB Actinobacillus pleuropneumoniae serovar 3 str. JL03 rod-shape-determining protein RodA YP_001652627.1 1787639 R 434271 CDS YP_001652628.1 165977035 5852431 complement(1788756..1790717) 1 NC_010278.1 penicillin binding protein 2 1790717 mrdA 5852431 mrdA Actinobacillus pleuropneumoniae serovar 3 str. JL03 penicillin binding protein 2 YP_001652628.1 1788756 R 434271 CDS YP_001652629.1 165977036 5852621 complement(1790799..1791266) 1 NC_010278.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1791266 5852621 APJL_1633 Actinobacillus pleuropneumoniae serovar 3 str. JL03 rRNA large subunit methyltransferase YP_001652629.1 1790799 R 434271 CDS YP_001652630.1 165977037 5852364 complement(1791289..1791603) 1 NC_010278.1 plant Iojap-like protein 1791603 5852364 APJL_1634 Actinobacillus pleuropneumoniae serovar 3 str. JL03 plant Iojap-like protein YP_001652630.1 1791289 R 434271 CDS YP_001652631.1 165977038 5852600 complement(1791825..1794419) 1 NC_010278.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1794419 mutS 5852600 mutS Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA mismatch repair protein MutS YP_001652631.1 1791825 R 434271 CDS YP_001652632.1 165977039 5852608 complement(1794585..1795334) 1 NC_010278.1 polar amino acid ABC transporter ATPase 1795334 glnQ 5852608 glnQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 polar amino acid ABC transporter ATPase YP_001652632.1 1794585 R 434271 CDS YP_001652633.1 165977040 5852374 complement(1795356..1796009) 1 NC_010278.1 amino acid ABC transporter permease 1796009 artM2 5852374 artM2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 amino acid ABC transporter permease YP_001652633.1 1795356 R 434271 CDS YP_001652634.1 165977041 5852724 complement(1796222..1797520) 1 NC_010278.1 hypothetical protein 1797520 5852724 APJL_1638 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652634.1 1796222 R 434271 CDS YP_001652635.1 165977042 5852141 1797792..1798286 1 NC_010278.1 regulator of cell morphogenesis and NO signaling 1798286 5852141 APJL_1639 Actinobacillus pleuropneumoniae serovar 3 str. JL03 regulator of cell morphogenesis and NO signaling YP_001652635.1 1797792 D 434271 CDS YP_001652636.1 165977043 5852815 complement(1798365..1798694) 1 NC_010278.1 drug resistance protein 1798694 5852815 APJL_1640 Actinobacillus pleuropneumoniae serovar 3 str. JL03 drug resistance protein YP_001652636.1 1798365 R 434271 CDS YP_001652637.1 165977044 5852798 complement(1798783..1799073) 1 NC_010278.1 hypothetical protein 1799073 5852798 APJL_1641 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652637.1 1798783 R 434271 CDS YP_001652638.1 165977045 5852799 complement(1799227..1799859) 1 NC_010278.1 hypothetical protein 1799859 5852799 APJL_1642 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652638.1 1799227 R 434271 CDS YP_001652639.1 165977046 5852816 complement(1800032..1800325) 1 NC_010278.1 hypothetical protein 1800325 5852816 APJL_1643 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652639.1 1800032 R 434271 CDS YP_001652640.1 165977047 5852822 complement(1800341..1801153) 1 NC_010278.1 urease accessory protein UreH 1801153 ureH 5852822 ureH Actinobacillus pleuropneumoniae serovar 3 str. JL03 urease accessory protein UreH YP_001652640.1 1800341 R 434271 CDS YP_001652641.1 165977048 5852801 complement(1801322..1801957) 1 NC_010278.1 urease accessory protein UreG 1801957 ureG 5852801 ureG Actinobacillus pleuropneumoniae serovar 3 str. JL03 urease accessory protein UreG YP_001652641.1 1801322 R 434271 CDS YP_001652642.1 165977049 5852857 complement(1801978..1802661) 1 NC_010278.1 urease accessory protein UreF 1802661 ureF 5852857 ureF Actinobacillus pleuropneumoniae serovar 3 str. JL03 urease accessory protein UreF YP_001652642.1 1801978 R 434271 CDS YP_001652643.1 165977050 5852813 complement(1802673..1803251) 1 NC_010278.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1803251 ureE 5852813 ureE Actinobacillus pleuropneumoniae serovar 3 str. JL03 urease accessory protein UreE YP_001652643.1 1802673 R 434271 CDS YP_001652644.1 165977051 5852075 complement(1803367..1803984) 1 NC_010278.1 UreX 1803984 ureX 5852075 ureX Actinobacillus pleuropneumoniae serovar 3 str. JL03 UreX YP_001652644.1 1803367 R 434271 CDS YP_001652645.1 165977052 5852076 complement(1804108..1805826) 1 NC_010278.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1805826 ureC 5852076 ureC Actinobacillus pleuropneumoniae serovar 3 str. JL03 urease subunit alpha YP_001652645.1 1804108 R 434271 CDS YP_001652646.1 165977053 5852852 complement(1805837..1806142) 1 NC_010278.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 1806142 ureB 5852852 ureB Actinobacillus pleuropneumoniae serovar 3 str. JL03 urease subunit beta YP_001652646.1 1805837 R 434271 CDS YP_001652647.1 165977054 5851806 complement(1806332..1806634) 1 NC_010278.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1806634 ureA 5851806 ureA Actinobacillus pleuropneumoniae serovar 3 str. JL03 urease subunit gamma YP_001652647.1 1806332 R 434271 CDS YP_001652648.1 165977055 5852835 complement(1806706..1807608) 1 NC_010278.1 urea transport protein 1807608 utp 5852835 utp Actinobacillus pleuropneumoniae serovar 3 str. JL03 urea transport protein YP_001652648.1 1806706 R 434271 CDS YP_001652649.1 165977056 5852838 complement(1807646..1808275) 1 NC_010278.1 cobalt ABC transporter ATPase 1808275 cbiO 5852838 cbiO Actinobacillus pleuropneumoniae serovar 3 str. JL03 cobalt ABC transporter ATPase YP_001652649.1 1807646 R 434271 CDS YP_001652650.1 165977057 5852837 complement(1808298..1808915) 1 NC_010278.1 cobalt ABC transporter permease CbiQ 1808915 cbiQ 5852837 cbiQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 cobalt ABC transporter permease CbiQ YP_001652650.1 1808298 R 434271 CDS YP_001652651.1 165977058 5852849 complement(1808922..1809530) 1 NC_010278.1 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1809530 cbiM 5852849 cbiM Actinobacillus pleuropneumoniae serovar 3 str. JL03 cobalt transport protein CbiM YP_001652651.1 1808922 R 434271 CDS YP_001652652.1 165977059 5851726 complement(1809531..1810013) 1 NC_010278.1 putative cytoplasmic membrane protein CbiL 1810013 cbiL 5851726 cbiL Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative cytoplasmic membrane protein CbiL YP_001652652.1 1809531 R 434271 CDS YP_001652653.1 165977060 5852843 complement(1810013..1810699) 1 NC_010278.1 hypothetical protein 1810699 5852843 APJL_1657 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652653.1 1810013 R 434271 CDS YP_001652654.1 165977061 5852844 1811042..1811797 1 NC_010278.1 putative LysR-type transcriptional regulator 1811797 5852844 APJL_1658 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative LysR-type transcriptional regulator YP_001652654.1 1811042 D 434271 CDS YP_001652655.1 165977062 5851154 complement(1811876..1812337) 1 NC_010278.1 hypothetical protein 1812337 5851154 APJL_1659 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652655.1 1811876 R 434271 CDS YP_001652656.1 165977063 5850883 complement(1812565..1814430) 1 NC_010278.1 di- and tricarboxylate transporter 1814430 5850883 APJL_1660 Actinobacillus pleuropneumoniae serovar 3 str. JL03 di- and tricarboxylate transporter YP_001652656.1 1812565 R 434271 CDS YP_001652657.1 165977064 5852851 complement(1814491..1815015) 1 NC_010278.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 1815015 mtlR 5852851 mtlR Actinobacillus pleuropneumoniae serovar 3 str. JL03 mannitol repressor protein YP_001652657.1 1814491 R 434271 CDS YP_001652658.1 165977065 5851216 complement(1815015..1816154) 1 NC_010278.1 mannitol-1-phosphate 5-dehydrogenase 1816154 mtlD 5851216 mtlD Actinobacillus pleuropneumoniae serovar 3 str. JL03 mannitol-1-phosphate 5-dehydrogenase YP_001652658.1 1815015 R 434271 CDS YP_001652659.1 165977066 5850721 complement(1816241..1818142) 1 NC_010278.1 phosphotransferase system, mannitol-specific IIBC component 1818142 mtlA 5850721 mtlA Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphotransferase system, mannitol-specific IIBC component YP_001652659.1 1816241 R 434271 CDS YP_001652660.1 165977067 5850730 complement(1818451..1820283) 1 NC_010278.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1820283 glmS 5850730 glmS Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucosamine--fructose-6-phosphate aminotransferase YP_001652660.1 1818451 R 434271 CDS YP_001652661.1 165977068 5850736 complement(1820407..1821165) 1 NC_010278.1 glucitol operon repressor 1821165 5850736 APJL_1665 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucitol operon repressor YP_001652661.1 1820407 R 434271 CDS YP_001652662.1 165977069 5850798 complement(1821303..1821503) 1 NC_010278.1 hypothetical protein 1821503 5850798 APJL_1666 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652662.1 1821303 R 434271 CDS YP_001652663.1 165977070 5850746 complement(1821602..1822594) 1 NC_010278.1 glycosyltransferase 1822594 5850746 APJL_1667 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycosyltransferase YP_001652663.1 1821602 R 434271 CDS YP_001652664.1 165977071 5850753 complement(1822643..1824505) 1 NC_010278.1 O-linked N-acetylglucosaminetransferase 1824505 5850753 APJL_1668 Actinobacillus pleuropneumoniae serovar 3 str. JL03 O-linked N-acetylglucosaminetransferase YP_001652664.1 1822643 R 434271 CDS YP_001652665.1 165977072 5850763 complement(1824521..1825852) 1 NC_010278.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 1825852 rimO 5850763 rimO Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosomal protein S12 methylthiotransferase YP_001652665.1 1824521 R 434271 CDS YP_001652666.1 165977073 5850764 complement(1826025..1826723) 1 NC_010278.1 MTA/SAH nucleosidase 1826723 mtn 5850764 mtn Actinobacillus pleuropneumoniae serovar 3 str. JL03 MTA/SAH nucleosidase YP_001652666.1 1826025 R 434271 CDS YP_001652667.1 165977074 5850781 complement(1826723..1827430) 1 NC_010278.1 thiol-disulfide isomerase and thioredoxin 1827430 5850781 APJL_1671 Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol-disulfide isomerase and thioredoxin YP_001652667.1 1826723 R 434271 CDS YP_001652668.1 165977075 5850782 complement(1827497..1827718) 1 NC_010278.1 hypothetical protein 1827718 5850782 APJL_1672 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652668.1 1827497 R 434271 CDS YP_001652669.1 165977076 5850789 1827809..1828528 1 NC_010278.1 FKBP-type peptidyl-prolyl cis-trans isomerase 1828528 fkpA1 5850789 fkpA1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 FKBP-type peptidyl-prolyl cis-trans isomerase YP_001652669.1 1827809 D 434271 CDS YP_001652670.1 165977077 5850800 1828640..1829299 1 NC_010278.1 hypothetical protein 1829299 5850800 APJL_1674 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652670.1 1828640 D 434271 CDS YP_001652671.1 165977078 5850806 1829299..1829676 1 NC_010278.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 1829676 5850806 APJL_1675 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfur transfer complex subunit TusD YP_001652671.1 1829299 D 434271 CDS YP_001652672.1 165977079 5851102 1829679..1830050 1 NC_010278.1 hypothetical protein 1830050 5851102 APJL_1676 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652672.1 1829679 D 434271 CDS YP_001652673.1 165977080 5850808 1830063..1830332 1 NC_010278.1 hypothetical protein 1830332 5850808 APJL_1677 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652673.1 1830063 D 434271 CDS YP_001652674.1 165977081 5851208 complement(1836330..1836749) 1 NC_010278.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1836749 atpC 5851208 atpC Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit epsilon YP_001652674.1 1836330 R 434271 CDS YP_001652675.1 165977082 5850877 complement(1836789..1838162) 1 NC_010278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1838162 atpD 5850877 atpD Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit beta YP_001652675.1 1836789 R 434271 CDS YP_001652676.1 165977083 5852826 complement(1838176..1839042) 1 NC_010278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1839042 atpG 5852826 atpG Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit gamma YP_001652676.1 1838176 R 434271 CDS YP_001652677.1 165977084 5850894 complement(1839065..1840606) 1 NC_010278.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1840606 atpA 5850894 atpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit alpha YP_001652677.1 1839065 R 434271 CDS YP_001652678.1 165977085 5850906 complement(1840619..1841152) 1 NC_010278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1841152 atpH 5850906 atpH Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit delta YP_001652678.1 1840619 R 434271 CDS YP_001652679.1 165977086 5851207 complement(1841166..1841636) 1 NC_010278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1841636 atpF 5851207 atpF Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit B YP_001652679.1 1841166 R 434271 CDS YP_001652680.1 165977087 5850908 complement(1841696..1841950) 1 NC_010278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1841950 atpE 5850908 atpE Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit C YP_001652680.1 1841696 R 434271 CDS YP_001652681.1 165977088 5850913 complement(1842069..1842857) 1 NC_010278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1842857 atpB 5850913 atpB Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit A YP_001652681.1 1842069 R 434271 CDS YP_001652682.1 165977089 5850914 complement(1842882..1843265) 1 NC_010278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 1843265 atpI 5850914 atpI Actinobacillus pleuropneumoniae serovar 3 str. JL03 F0F1 ATP synthase subunit I YP_001652682.1 1842882 R 434271 CDS YP_001652683.1 165977090 5851079 complement(1843626..1844243) 1 NC_010278.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1844243 gidB 5851079 gidB Actinobacillus pleuropneumoniae serovar 3 str. JL03 16S rRNA methyltransferase GidB YP_001652683.1 1843626 R 434271 CDS YP_001652684.1 165977091 5850915 complement(1844343..1846235) 1 NC_010278.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1846235 gidA 5850915 gidA Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001652684.1 1844343 R 434271 CDS YP_001652685.1 165977092 5850922 1846706..1847497 1 NC_010278.1 HAD superfamily hydrolase 1847497 cof 5850922 cof Actinobacillus pleuropneumoniae serovar 3 str. JL03 HAD superfamily hydrolase YP_001652685.1 1846706 D 434271 CDS YP_001652686.1 165977093 5851150 complement(1847547..1848329) 1 NC_010278.1 amino acid ABC transporter substrate-binding protein 1848329 5851150 APJL_1690 Actinobacillus pleuropneumoniae serovar 3 str. JL03 amino acid ABC transporter substrate-binding protein YP_001652686.1 1847547 R 434271 CDS YP_001652687.1 165977094 5850932 complement(1848541..1849017) 1 NC_010278.1 hypothetical protein 1849017 5850932 APJL_1691 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652687.1 1848541 R 434271 CDS YP_001652688.1 165977095 5851097 complement(1849020..1849397) 1 NC_010278.1 hypothetical protein 1849397 5851097 APJL_1692 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652688.1 1849020 R 434271 CDS YP_001652689.1 165977096 5850937 complement(1849485..1850312) 1 NC_010278.1 PTS system mannose-specific transporter subunit IID 1850312 5850937 APJL_1693 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system mannose-specific transporter subunit IID YP_001652689.1 1849485 R 434271 CDS YP_001652690.1 165977097 5850939 complement(1850323..1851117) 1 NC_010278.1 PTS system mannose-specific transporter subunit IIC 1851117 5850939 APJL_1694 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system mannose-specific transporter subunit IIC YP_001652690.1 1850323 R 434271 CDS YP_001652691.1 165977098 5851086 complement(1851132..1852100) 1 NC_010278.1 phosphotransferase system,mannose/fructose/N-acetylgalactosamine-specific component IIB 1852100 5851086 APJL_1695 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphotransferase system,mannose/fructose/N-acetylgalactosamine-specific component IIB YP_001652691.1 1851132 R 434271 CDS YP_001652692.1 165977099 5850942 complement(1852290..1853639) 1 NC_010278.1 gluconate permease 1853639 gntP 5850942 gntP Actinobacillus pleuropneumoniae serovar 3 str. JL03 gluconate permease YP_001652692.1 1852290 R 434271 CDS YP_001652693.1 165977100 5850953 1853817..1854332 1 NC_010278.1 gluconate kinase 1854332 gntK 5850953 gntK Actinobacillus pleuropneumoniae serovar 3 str. JL03 gluconate kinase YP_001652693.1 1853817 D 434271 CDS YP_001652694.1 165977101 5850970 complement(1854404..1855504) 1 NC_010278.1 transcriptional regulator 1855504 purR2 5850970 purR2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652694.1 1854404 R 434271 CDS YP_001652695.1 165977102 5850975 1855540..1856529 1 NC_010278.1 ribose operon repressor 1856529 rbsR 5850975 rbsR Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribose operon repressor YP_001652695.1 1855540 D 434271 CDS YP_001652696.1 165977103 5850986 1856650..1857069 1 NC_010278.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 1857069 rbsD 5850986 rbsD Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-ribose pyranase YP_001652696.1 1856650 D 434271 CDS YP_001652697.1 165977104 5850988 1857082..1858563 1 NC_010278.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 1858563 rbsA 5850988 rbsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-ribose transporter ATP-binding protein YP_001652697.1 1857082 D 434271 CDS YP_001652698.1 165977105 5850807 1858616..1859575 1 NC_010278.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 1859575 rbsC 5850807 rbsC Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribose ABC transporter permease YP_001652698.1 1858616 D 434271 CDS YP_001652699.1 165977106 5850997 1859599..1860471 1 NC_010278.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 1860471 rbsB2 5850997 rbsB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-ribose transporter subunit RbsB YP_001652699.1 1859599 D 434271 CDS YP_001652700.1 165977107 5851015 1860544..1861455 1 NC_010278.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 1861455 rbsK2 5851015 rbsK2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribokinase YP_001652700.1 1860544 D 434271 CDS YP_001652701.1 165977108 5851276 1861690..1864107 1 NC_010278.1 anaerobic dimethyl sulfoxide reductase subunit A 1864107 dmsA 5851276 dmsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 anaerobic dimethyl sulfoxide reductase subunit A YP_001652701.1 1861690 D 434271 CDS YP_001652702.1 165977109 5851016 1864117..1864734 1 NC_010278.1 anaerobic dimethyl sulfoxide reductase subunit B 1864734 dmsB 5851016 dmsB Actinobacillus pleuropneumoniae serovar 3 str. JL03 anaerobic dimethyl sulfoxide reductase subunit B YP_001652702.1 1864117 D 434271 CDS YP_001652703.1 165977110 5851028 1864736..1865569 1 NC_010278.1 anaerobic dimethyl sulfoxide reductase subunit C 1865569 dmsC 5851028 dmsC Actinobacillus pleuropneumoniae serovar 3 str. JL03 anaerobic dimethyl sulfoxide reductase subunit C YP_001652703.1 1864736 D 434271 CDS YP_001652704.1 165977111 5851031 1865625..1866230 1 NC_010278.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1866230 5851031 APJL_1708 Actinobacillus pleuropneumoniae serovar 3 str. JL03 twin-argninine leader-binding protein DmsD YP_001652704.1 1865625 D 434271 CDS YP_001652705.1 165977112 5851047 1866234..1866752 1 NC_010278.1 ferredoxin 1866752 5851047 APJL_1709 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferredoxin YP_001652705.1 1866234 D 434271 CDS YP_001652706.1 165977113 5851060 complement(1866749..1867378) 1 NC_010278.1 hypothetical protein 1867378 5851060 APJL_1710 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652706.1 1866749 R 434271 CDS YP_001652707.1 165977114 5851062 1867660..1868151 1 NC_010278.1 Abi family protein 1868151 5851062 APJL_1711 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Abi family protein YP_001652707.1 1867660 D 434271 CDS YP_001652708.1 165977115 5851065 1868238..1868678 1 NC_010278.1 abortive infection bacteriophage resistance protein 1868678 5851065 APJL_1712 Actinobacillus pleuropneumoniae serovar 3 str. JL03 abortive infection bacteriophage resistance protein YP_001652708.1 1868238 D 434271 CDS YP_001652709.1 165977116 5850726 complement(1868834..1869475) 1 NC_010278.1 hypothetical protein 1869475 5850726 APJL_1713 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652709.1 1868834 R 434271 CDS YP_001652710.1 165977117 5851078 complement(1869532..1873428) 1 NC_010278.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 1873428 purL 5851078 purL Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylformylglycinamidine synthase YP_001652710.1 1869532 R 434271 CDS YP_001652711.1 165977118 5850735 1873655..1874401 1 NC_010278.1 L-fucose operon activator 1874401 fucR 5850735 fucR Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-fucose operon activator YP_001652711.1 1873655 D 434271 CDS YP_001652712.1 165977119 5851092 1874623..1876389 1 NC_010278.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 1876389 fucI 5851092 fucI Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-fucose isomerase YP_001652712.1 1874623 D 434271 CDS YP_001652713.1 165977120 5851093 1876466..1877899 1 NC_010278.1 L-fuculokinase 1877899 fucK 5851093 fucK Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-fuculokinase YP_001652713.1 1876466 D 434271 CDS YP_001652714.1 165977121 5851113 1878034..1878468 1 NC_010278.1 fucose operon FucU protein 1878468 fucU 5851113 fucU Actinobacillus pleuropneumoniae serovar 3 str. JL03 fucose operon FucU protein YP_001652714.1 1878034 D 434271 CDS YP_001652715.1 165977122 5851115 1878519..1879169 1 NC_010278.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 1879169 fucA 5851115 fucA Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-fuculose phosphate aldolase YP_001652715.1 1878519 D 434271 CDS YP_001652716.1 165977123 5851110 1879223..1880512 1 NC_010278.1 L-fucose permease 1880512 fucP 5851110 fucP Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-fucose permease YP_001652716.1 1879223 D 434271 CDS YP_001652717.1 165977124 5851118 1880632..1881783 1 NC_010278.1 L-1,2-propanediol oxidoreductase 1881783 fucO 5851118 fucO Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-1,2-propanediol oxidoreductase YP_001652717.1 1880632 D 434271 CDS YP_001652718.1 165977125 5851257 1881986..1882627 1 NC_010278.1 periplasmic/secreted protein 1882627 5851257 APJL_1722 Actinobacillus pleuropneumoniae serovar 3 str. JL03 periplasmic/secreted protein YP_001652718.1 1881986 D 434271 CDS YP_001652719.1 165977126 5851128 1882829..1883488 1 NC_010278.1 ABC transporter permease 1883488 5851128 APJL_1723 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter permease YP_001652719.1 1882829 D 434271 CDS YP_001652720.1 165977127 5851130 1883478..1884146 1 NC_010278.1 ABC transporter permease 1884146 5851130 APJL_1724 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter permease YP_001652720.1 1883478 D 434271 CDS YP_001652721.1 165977128 5850773 1884147..1884878 1 NC_010278.1 ABC transporter ATP-binding protein 1884878 5850773 APJL_1725 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001652721.1 1884147 D 434271 CDS YP_001652722.1 165977129 5851137 1884939..1885775 1 NC_010278.1 putative ABC transporter periplasmic binding protein 1885775 5851137 APJL_1726 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative ABC transporter periplasmic binding protein YP_001652722.1 1884939 D 434271 CDS YP_001652723.1 165977130 5851151 1885908..1887977 1 NC_010278.1 capsule polysaccharide modification protein 1887977 lipA2 5851151 lipA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 capsule polysaccharide modification protein YP_001652723.1 1885908 D 434271 CDS YP_001652724.1 165977131 5851165 1888000..1889220 1 NC_010278.1 PhyB, capsule biosynthetic locus protein 1889220 phyB 5851165 phyB Actinobacillus pleuropneumoniae serovar 3 str. JL03 PhyB, capsule biosynthetic locus protein YP_001652724.1 1888000 D 434271 CDS YP_001652725.1 165977132 5851172 complement(1889289..1890317) 1 NC_010278.1 hypothetical protein 1890317 5851172 APJL_1729 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652725.1 1889289 R 434271 CDS YP_001652726.1 165977133 5851139 complement(1890412..1891092) 1 NC_010278.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1891092 ulaD 5851139 ulaD Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-keto-L-gulonate-6-phosphate decarboxylase YP_001652726.1 1890412 R 434271 CDS YP_001652727.1 165977134 5851385 complement(1891163..1891630) 1 NC_010278.1 PTS system enzyme II-A permease 1891630 5851385 APJL_1731 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system enzyme II-A permease YP_001652727.1 1891163 R 434271 CDS YP_001652728.1 165977135 5851801 complement(1891708..1893489) 1 NC_010278.1 PTS system ascorbate-specific transporter subunits IICB 1893489 sgaT 5851801 sgaT Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system ascorbate-specific transporter subunits IICB YP_001652728.1 1891708 R 434271 CDS YP_001652729.1 165977136 5851089 1893989..1895080 1 NC_010278.1 putative L-ascorbate 6-phosphate lactonase 1895080 ulaG 5851089 ulaG Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative L-ascorbate 6-phosphate lactonase YP_001652729.1 1893989 D 434271 CDS YP_001652730.1 165977137 5851237 1895182..1895928 1 NC_010278.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 1895928 5851237 APJL_1734 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional repressor UlaR YP_001652730.1 1895182 D 434271 CDS YP_001652731.1 165977138 5850848 1896014..1896874 1 NC_010278.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 1896874 sgbU 5850848 sgbU Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative L-xylulose 5-phosphate 3-epimerase YP_001652731.1 1896014 D 434271 CDS YP_001652732.1 165977139 5851255 1896868..1897581 1 NC_010278.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 1897581 araD 5851255 araD Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-ribulose-5-phosphate 4-epimerase YP_001652732.1 1896868 D 434271 CDS YP_001652733.1 165977140 5851259 complement(1897758..1898363) 1 NC_010278.1 FKBP-type peptidyl-prolyl cis-trans isomerase 1 1898363 fkpA2 5851259 fkpA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 FKBP-type peptidyl-prolyl cis-trans isomerase 1 YP_001652733.1 1897758 R 434271 CDS YP_001652734.1 165977141 5850787 1898690..1899427 1 NC_010278.1 hypothetical protein 1899427 5850787 APJL_1738 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652734.1 1898690 D 434271 CDS YP_001652735.1 165977142 5851266 complement(1899568..1900017) 1 NC_010278.1 hypothetical protein 1900017 5851266 APJL_1739 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652735.1 1899568 R 434271 CDS YP_001652736.1 165977143 5851210 1900117..1901466 1 NC_010278.1 colicin import membrane protein 1901466 tolA2 5851210 tolA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 colicin import membrane protein YP_001652736.1 1900117 D 434271 CDS YP_001652737.1 165977144 5851270 1901613..1903019 1 NC_010278.1 hypothetical protein 1903019 5851270 APJL_1741 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652737.1 1901613 D 434271 CDS YP_001652738.1 165977145 5850780 complement(1903080..1904006) 1 NC_010278.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 1904006 rfaD 5850780 rfaD Actinobacillus pleuropneumoniae serovar 3 str. JL03 ADP-L-glycero-D-manno-heptose-6-epimerase YP_001652738.1 1903080 R 434271 CDS YP_001652739.1 165977146 5851201 complement(1904146..1904610) 1 NC_010278.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1904610 def 5851201 def Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide deformylase YP_001652739.1 1904146 R 434271 CDS YP_001652740.1 165977147 5851284 1904844..1905998 1 NC_010278.1 Smf protein 1905998 smf 5851284 smf Actinobacillus pleuropneumoniae serovar 3 str. JL03 Smf protein YP_001652740.1 1904844 D 434271 CDS YP_001652741.1 165977148 5850929 complement(1906042..1908048) 1 NC_010278.1 putative oligopeptide transporter 1908048 5850929 APJL_1745 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative oligopeptide transporter YP_001652741.1 1906042 R 434271 CDS YP_001652742.1 165977149 5851286 1908160..1908261 1 NC_010278.1 hypothetical protein 1908261 5851286 APJL_1746 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652742.1 1908160 D 434271 CDS YP_001652743.1 165977150 5851291 complement(1908269..1909624) 1 NC_010278.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1909624 ulaA 5851291 ulaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 PTS system ascorbate-specific transporter subunit IIC YP_001652743.1 1908269 R 434271 CDS YP_001652744.1 165977151 5850829 complement(1909633..1909905) 1 NC_010278.1 phosphotransferase system, galactitol-specific IIB component 1909905 sgaB 5850829 sgaB Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphotransferase system, galactitol-specific IIB component YP_001652744.1 1909633 R 434271 CDS YP_001652745.1 165977152 5851292 1910208..1910621 1 NC_010278.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1910621 secE 5851292 secE Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit SecE YP_001652745.1 1910208 D 434271 CDS YP_001652746.1 165977153 5850854 1910656..1911186 1 NC_010278.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1911186 nusG 5850854 nusG Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcription antitermination protein NusG YP_001652746.1 1910656 D 434271 CDS YP_001652747.2 408843740 5851299 <1911528..1911902 1 NC_010278.1 truncated; 50S ribosomal protein L11 1911902 rplK 5851299 rplK Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L11 YP_001652747.2 <1911528 D 434271 CDS YP_001652748.1 165977155 5851312 1911907..1912596 1 NC_010278.1 50S ribosomal protein L1 1912596 rplA 5851312 rplA Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L1 YP_001652748.1 1911907 D 434271 CDS YP_001652749.1 165977156 5850955 1913437..1913805 1 NC_010278.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1913805 rplL 5850955 rplL Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L7/L12 YP_001652749.1 1913437 D 434271 CDS YP_001652750.1 165977157 5851316 1913969..1914241 1 NC_010278.1 hypothetical protein 1914241 5851316 APJL_1756 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652750.1 1913969 D 434271 CDS YP_001652751.1 165977158 5851568 1914246..1915502 1 NC_010278.1 hypothetical protein 1915502 5851568 APJL_1757 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652751.1 1914246 D 434271 CDS YP_001652752.1 165977159 5851580 1915660..1915878 1 NC_010278.1 hypothetical protein 1915878 5851580 APJL_1758 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652752.1 1915660 D 434271 CDS YP_001652753.1 165977160 5851355 1915889..1916428 1 NC_010278.1 hypothetical protein 1916428 5851355 APJL_1759 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652753.1 1915889 D 434271 CDS YP_001652754.1 165977161 5851585 1916503..1916817 1 NC_010278.1 hypothetical protein 1916817 5851585 APJL_1760 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652754.1 1916503 D 434271 CDS YP_001652755.1 165977162 5852035 1916914..1917699 1 NC_010278.1 hypothetical protein 1917699 5852035 APJL_1761 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652755.1 1916914 D 434271 CDS YP_001652756.1 165977163 5850867 1918000..1922028 1 NC_010278.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1922028 rpoB 5850867 rpoB Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-directed RNA polymerase subunit beta YP_001652756.1 1918000 D 434271 CDS YP_001652757.1 165977164 5850976 1922154..1926425 1 NC_010278.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1926425 rpoC 5850976 rpoC Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-directed RNA polymerase subunit beta' YP_001652757.1 1922154 D 434271 CDS YP_001652758.1 165977165 5851858 1926587..1928002 1 NC_010278.1 hypothetical protein 1928002 5851858 APJL_1764 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652758.1 1926587 D 434271 CDS YP_001652759.1 165977166 5851170 1927995..1928567 1 NC_010278.1 hypothetical protein 1928567 5851170 APJL_1765 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652759.1 1927995 D 434271 CDS YP_001652760.1 165977167 5850951 1929188..1929418 1 NC_010278.1 hypothetical protein 1929418 5850951 APJL_1766 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652760.1 1929188 D 434271 CDS YP_001652761.1 165977168 5851964 1929418..1929816 1 NC_010278.1 nucleic acid-binding protein 1929816 5851964 APJL_1767 Actinobacillus pleuropneumoniae serovar 3 str. JL03 nucleic acid-binding protein YP_001652761.1 1929418 D 434271 CDS YP_001652762.1 165977169 5851203 complement(1929952..1930368) 1 NC_010278.1 hypothetical protein 1930368 5851203 APJL_1768 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652762.1 1929952 R 434271 CDS YP_001652763.1 165977170 5851565 1930614..1931264 1 NC_010278.1 hypothetical protein 1931264 5851565 APJL_1769 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652763.1 1930614 D 434271 CDS YP_001652764.1 165977171 5850788 complement(1931337..1931996) 1 NC_010278.1 hypothetical protein 1931996 5850788 APJL_1770 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652764.1 1931337 R 434271 CDS YP_001652765.1 165977172 5851244 complement(1932310..1933632) 1 NC_010278.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1933632 hslU 5851244 hslU Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent protease ATP-binding subunit HslU YP_001652765.1 1932310 R 434271 CDS YP_001652766.1 165977173 5851960 complement(1933898..1934419) 1 NC_010278.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1934419 hslV 5851960 hslV Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent protease peptidase subunit YP_001652766.1 1933898 R 434271 CDS YP_001652767.1 165977174 5851460 complement(1934497..1935210) 1 NC_010278.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1935210 sfsA 5851460 sfsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 sugar fermentation stimulation protein A YP_001652767.1 1934497 R 434271 CDS YP_001652768.1 165977175 5851467 complement(1935517..1935909) 1 NC_010278.1 lactoylglutathione lyase 1935909 gloA2 5851467 gloA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lactoylglutathione lyase YP_001652768.1 1935517 R 434271 CDS YP_001652769.1 165977176 5851398 1936009..1937154 1 NC_010278.1 A/G-specific adenine glycosylase 1937154 mutY 5851398 mutY Actinobacillus pleuropneumoniae serovar 3 str. JL03 A/G-specific adenine glycosylase YP_001652769.1 1936009 D 434271 CDS YP_001652770.1 165977177 5851138 1937158..1937433 1 NC_010278.1 hypothetical protein 1937433 5851138 APJL_1776 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652770.1 1937158 D 434271 CDS YP_001652771.1 165977178 5851305 1937451..1938548 1 NC_010278.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 1938548 mltC 5851305 mltC Actinobacillus pleuropneumoniae serovar 3 str. JL03 murein transglycosylase C YP_001652771.1 1937451 D 434271 CDS YP_001652772.1 165977179 5851424 1939542..1940933 1 NC_010278.1 signal recognition particle GTPase 1940933 ffh 5851424 ffh Actinobacillus pleuropneumoniae serovar 3 str. JL03 signal recognition particle GTPase YP_001652772.1 1939542 D 434271 CDS YP_001652773.1 165977180 5851426 complement(1941087..1942751) 1 NC_010278.1 2',3'-cyclic-nucleotide 2'-phosphodiesterase 1942751 5851426 APJL_1779 Actinobacillus pleuropneumoniae serovar 3 str. JL03 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_001652773.1 1941087 R 434271 CDS YP_001652774.1 165977181 5851536 complement(1942943..1944109) 1 NC_010278.1 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 1944109 ubiF 5851536 ubiF Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_001652774.1 1942943 R 434271 CDS YP_001652775.1 165977182 5851425 complement(1944143..1944451) 1 NC_010278.1 transcriptional regulator 1944451 5851425 APJL_1781 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652775.1 1944143 R 434271 CDS YP_001652776.1 165977183 5851391 1944783..1946309 1 NC_010278.1 competence protein M 1946309 comM 5851391 comM Actinobacillus pleuropneumoniae serovar 3 str. JL03 competence protein M YP_001652776.1 1944783 D 434271 CDS YP_001652777.1 165977184 5851464 1946432..1947526 1 NC_010278.1 outer membrane lipoprotein A 1947526 5851464 APJL_1783 Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane lipoprotein A YP_001652777.1 1946432 D 434271 CDS YP_001652778.1 165977185 5851875 complement(1947577..1948341) 1 NC_010278.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 1948341 5851875 APJL_1784 Actinobacillus pleuropneumoniae serovar 3 str. JL03 acyl-CoA thioester hydrolase YfbB YP_001652778.1 1947577 R 434271 CDS YP_001652779.1 165977186 5851934 complement(1948341..1950047) 1 NC_010278.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1950047 menD 5851934 menD Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_001652779.1 1948341 R 434271 CDS YP_001652780.1 165977187 5851793 1950300..1950893 1 NC_010278.1 acylneuraminate cytidylyltransferase 1950893 neuA 5851793 neuA Actinobacillus pleuropneumoniae serovar 3 str. JL03 acylneuraminate cytidylyltransferase YP_001652780.1 1950300 D 434271 CDS YP_001652781.1 165977188 5851563 1950931..1951620 1 NC_010278.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1951620 nanE 5851563 nanE Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetylmannosamine-6-phosphate 2-epimerase YP_001652781.1 1950931 D 434271 CDS YP_001652782.1 165977189 5851336 1951630..1952502 1 NC_010278.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 1952502 5851336 APJL_1788 Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetylmannosamine kinase YP_001652782.1 1951630 D 434271 CDS YP_001652783.1 165977190 5851538 1952523..1953401 1 NC_010278.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 1953401 nanA 5851538 nanA Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetylneuraminate lyase YP_001652783.1 1952523 D 434271 CDS YP_001652784.1 165977191 5851439 1953451..1954254 1 NC_010278.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 1954254 nagB 5851439 nagB Actinobacillus pleuropneumoniae serovar 3 str. JL03 glucosamine-6-phosphate deaminase YP_001652784.1 1953451 D 434271 CDS YP_001652785.1 165977192 5850832 1954306..1955451 1 NC_010278.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 1955451 nagA 5850832 nagA Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-acetylglucosamine-6-phosphate deacetylase YP_001652785.1 1954306 D 434271 CDS YP_001652786.1 165977193 5851567 complement(1955600..1956994) 1 NC_010278.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1956994 fumC 5851567 fumC Actinobacillus pleuropneumoniae serovar 3 str. JL03 fumarate hydratase YP_001652786.1 1955600 R 434271 CDS YP_001652787.1 165977194 5851332 complement(1957149..1957805) 1 NC_010278.1 DNA transformation protein 1957805 5851332 APJL_1793 Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA transformation protein YP_001652787.1 1957149 R 434271 CDS YP_001652788.1 165977195 5851449 1958213..1958524 1 NC_010278.1 30S ribosomal protein S10 1958524 rpsJ 5851449 rpsJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S10 YP_001652788.1 1958213 D 434271 CDS YP_001652789.1 165977196 5851386 1958550..1959176 1 NC_010278.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1959176 rplC 5851386 rplC Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L3 YP_001652789.1 1958550 D 434271 CDS YP_001652790.1 165977197 5851224 1959192..1959794 1 NC_010278.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1959794 rplD 5851224 rplD Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L4 YP_001652790.1 1959192 D 434271 CDS YP_001652791.1 165977198 5851394 1959791..1960096 1 NC_010278.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1960096 rplW 5851394 rplW Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L23 YP_001652791.1 1959791 D 434271 CDS YP_001652792.1 165977199 5851543 1960117..1960938 1 NC_010278.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1960938 rplB 5851543 rplB Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L2 YP_001652792.1 1960117 D 434271 CDS YP_001652793.1 165977200 5851461 1960966..1961241 1 NC_010278.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1961241 rpsS 5851461 rpsS Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S19 YP_001652793.1 1960966 D 434271 CDS YP_001652794.1 165977201 5851810 1961252..1961584 1 NC_010278.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1961584 rplV 5851810 rplV Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L22 YP_001652794.1 1961252 D 434271 CDS YP_001652795.1 165977202 5851974 1961603..1962310 1 NC_010278.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1962310 rpsC 5851974 rpsC Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S3 YP_001652795.1 1961603 D 434271 CDS YP_001652796.1 165977203 5851116 1962324..1962734 1 NC_010278.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1962734 rplP 5851116 rplP Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L16 YP_001652796.1 1962324 D 434271 CDS YP_001652797.1 165977204 5851452 1962734..1962925 1 NC_010278.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1962925 rpmC 5851452 rpmC Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L29 YP_001652797.1 1962734 D 434271 CDS YP_001652798.1 165977205 5851982 1962925..1963179 1 NC_010278.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1963179 rpsQ 5851982 rpsQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S17 YP_001652798.1 1962925 D 434271 CDS YP_001652799.1 165977206 5851132 1963419..1963790 1 NC_010278.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1963790 rplN 5851132 rplN Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L14 YP_001652799.1 1963419 D 434271 CDS YP_001652800.1 165977207 5851408 1963801..1964112 1 NC_010278.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1964112 rplX 5851408 rplX Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L24 YP_001652800.1 1963801 D 434271 CDS YP_001652801.1 165977208 5851716 1964130..1964669 1 NC_010278.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1964669 rplE 5851716 rplE Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L5 YP_001652801.1 1964130 D 434271 CDS YP_001652802.1 165977209 5851418 1964681..1964986 1 NC_010278.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1964986 rpsN 5851418 rpsN Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S14 YP_001652802.1 1964681 D 434271 CDS YP_001652803.1 165977210 5850947 1965023..1965415 1 NC_010278.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1965415 rpsH 5850947 rpsH Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S8 YP_001652803.1 1965023 D 434271 CDS YP_001652804.1 165977211 5850838 1965432..1965965 1 NC_010278.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1965965 rplF 5850838 rplF Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L6 YP_001652804.1 1965432 D 434271 CDS YP_001652805.1 165977212 5851396 1965980..1966333 1 NC_010278.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1966333 rplR 5851396 rplR Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L18 YP_001652805.1 1965980 D 434271 CDS YP_001652806.1 165977213 5851603 1966348..1966848 1 NC_010278.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1966848 rpsE 5851603 rpsE Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S5 YP_001652806.1 1966348 D 434271 CDS YP_001652807.1 165977214 5851182 1966855..1967034 1 NC_010278.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1967034 rpmD 5851182 rpmD Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L30 YP_001652807.1 1966855 D 434271 CDS YP_001652808.1 165977215 5850729 1967039..1967473 1 NC_010278.1 late assembly protein; 50S ribosomal protein L15 1967473 rplO 5850729 rplO Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L15 YP_001652808.1 1967039 D 434271 CDS YP_001652809.1 165977216 5850895 1967477..1968799 1 NC_010278.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1968799 secY 5850895 secY Actinobacillus pleuropneumoniae serovar 3 str. JL03 preprotein translocase subunit SecY YP_001652809.1 1967477 D 434271 CDS YP_001652810.1 165977217 5850812 1968825..1968938 1 NC_010278.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1968938 rpmJ 5850812 rpmJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L36 YP_001652810.1 1968825 D 434271 CDS YP_001652811.1 165977218 5851731 1969075..1969431 1 NC_010278.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1969431 rpsM 5851731 rpsM Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S13 YP_001652811.1 1969075 D 434271 CDS YP_001652812.1 165977219 5851297 1969448..1969837 1 NC_010278.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1969837 rpsK 5851297 rpsK Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S11 YP_001652812.1 1969448 D 434271 CDS YP_001652813.1 165977220 5851044 1969866..1970492 1 NC_010278.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1970492 rpsD 5851044 rpsD Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S4 YP_001652813.1 1969866 D 434271 CDS YP_001652814.1 165977221 5851099 1970558..1971547 1 NC_010278.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1971547 rpoA 5851099 rpoA Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-directed RNA polymerase subunit alpha YP_001652814.1 1970558 D 434271 CDS YP_001652815.1 165977222 5851724 1971583..1971966 1 NC_010278.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1971966 rplQ 5851724 rplQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L17 YP_001652815.1 1971583 D 434271 CDS YP_001652816.1 165977223 5851410 1972203..1972451 1 NC_010278.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1972451 rpsP 5851410 rpsP Actinobacillus pleuropneumoniae serovar 3 str. JL03 30S ribosomal protein S16 YP_001652816.1 1972203 D 434271 CDS YP_001652817.1 165977224 5851663 1972485..1973012 1 NC_010278.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1973012 rimM 5851663 rimM Actinobacillus pleuropneumoniae serovar 3 str. JL03 16S rRNA-processing protein RimM YP_001652817.1 1972485 D 434271 CDS YP_001652818.1 165977225 5851330 1973070..1973825 1 NC_010278.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1973825 trmD 5851330 trmD Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA (guanine-N(1)-)-methyltransferase YP_001652818.1 1973070 D 434271 CDS YP_001652819.1 165977226 5851454 1973851..1974201 1 NC_010278.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1974201 rplS 5851454 rplS Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L19 YP_001652819.1 1973851 D 434271 CDS YP_001652820.1 165977227 5851455 complement(1974371..1975564) 1 NC_010278.1 hypothetical protein 1975564 5851455 APJL_1826 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652820.1 1974371 R 434271 CDS YP_001652821.1 165977228 5851463 1975780..1976895 1 NC_010278.1 Fe3+-hydroxamate ABC transporter,periplasmic protein 1976895 5851463 APJL_1827 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Fe3+-hydroxamate ABC transporter,periplasmic protein YP_001652821.1 1975780 D 434271 CDS YP_001652822.1 165977229 5851347 1976898..1977935 1 NC_010278.1 Fe(III) dicitrate ABC transporter permease 1977935 5851347 APJL_1828 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Fe(III) dicitrate ABC transporter permease YP_001652822.1 1976898 D 434271 CDS YP_001652823.1 165977230 5851534 1977951..1978718 1 NC_010278.1 hemin import ATP-binding protein 1978718 hmuV 5851534 hmuV Actinobacillus pleuropneumoniae serovar 3 str. JL03 hemin import ATP-binding protein YP_001652823.1 1977951 D 434271 CDS YP_001652824.1 165977231 5851625 1978728..1979159 1 NC_010278.1 plastocyanin 1979159 5851625 APJL_1830 Actinobacillus pleuropneumoniae serovar 3 str. JL03 plastocyanin YP_001652824.1 1978728 D 434271 CDS YP_001652825.1 165977232 5851769 1979168..1980274 1 NC_010278.1 Fe3+-hydroxamate ABC transporter,periplasmic protein 1980274 5851769 APJL_1831 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Fe3+-hydroxamate ABC transporter,periplasmic protein YP_001652825.1 1979168 D 434271 CDS YP_001652826.1 165977233 5851787 1980330..1981181 1 NC_010278.1 hypothetical protein 1981181 5851787 APJL_1832 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652826.1 1980330 D 434271 CDS YP_001652827.1 165977234 5850775 complement(1981224..1981823) 1 NC_010278.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1981823 torD 5850775 torD Actinobacillus pleuropneumoniae serovar 3 str. JL03 chaperone protein TorD YP_001652827.1 1981224 R 434271 CDS YP_001652828.1 165977235 5851737 complement(1981823..1984306) 1 NC_010278.1 trimethylamine-n-oxide reductase 1984306 torA 5851737 torA Actinobacillus pleuropneumoniae serovar 3 str. JL03 trimethylamine-n-oxide reductase YP_001652828.1 1981823 R 434271 CDS YP_001652829.1 165977236 5851710 complement(1984316..1984936) 1 NC_010278.1 cytochrome c-type protein 1984936 torC2 5851710 torC2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cytochrome c-type protein YP_001652829.1 1984316 R 434271 CDS YP_001652830.1 165977237 5851805 1985130..1986044 1 NC_010278.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1986044 glyQ 5851805 glyQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycyl-tRNA synthetase subunit alpha YP_001652830.1 1985130 D 434271 CDS YP_001652831.1 165977238 5851695 1986087..1986470 1 NC_010278.1 hypothetical protein 1986470 5851695 APJL_1837 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652831.1 1986087 D 434271 CDS YP_001652832.1 165977239 5851349 1986943..1987347 1 NC_010278.1 hypothetical protein 1987347 5851349 APJL_1838 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652832.1 1986943 D 434271 CDS YP_001652833.1 165977240 5850824 1987385..1989454 1 NC_010278.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1989454 glyS 5850824 glyS Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycyl-tRNA synthetase subunit beta YP_001652833.1 1987385 D 434271 CDS YP_001652834.1 165977241 5851217 1989570..1989860 1 NC_010278.1 hypothetical protein 1989860 5851217 APJL_1840 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652834.1 1989570 D 434271 CDS YP_001652835.1 165977242 5851215 1989861..1990871 1 NC_010278.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1990871 xerC 5851215 xerC Actinobacillus pleuropneumoniae serovar 3 str. JL03 site-specific tyrosine recombinase XerC YP_001652835.1 1989861 D 434271 CDS YP_001652836.1 165977243 5851234 complement(1990875..1991264) 1 NC_010278.1 hypothetical protein 1991264 5851234 APJL_1842 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652836.1 1990875 R 434271 CDS YP_001652837.1 165977244 5851438 complement(1991328..1992074) 1 NC_010278.1 hypothetical protein 1992074 5851438 APJL_1843 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652837.1 1991328 R 434271 CDS YP_001652838.1 165977245 5850855 complement(1992116..1992847) 1 NC_010278.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 1992847 lpxH 5850855 lpxH Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-2,3-diacylglucosamine hydrolase YP_001652838.1 1992116 R 434271 CDS YP_001652839.1 165977246 5850755 complement(1992880..1993404) 1 NC_010278.1 hypothetical protein 1993404 5850755 APJL_1845 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652839.1 1992880 R 434271 CDS YP_001652840.1 165977247 5851014 complement(1993439..1994227) 1 NC_010278.1 putative deoxyribonuclease 1994227 5851014 APJL_1846 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative deoxyribonuclease YP_001652840.1 1993439 R 434271 CDS YP_001652841.1 165977248 5851162 complement(1994432..1994635) 1 NC_010278.1 hypothetical protein 1994635 5851162 APJL_1847 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652841.1 1994432 R 434271 CDS YP_001652842.1 165977249 5850945 1995317..1995949 1 NC_010278.1 hypothetical protein 1995949 5850945 APJL_1848 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652842.1 1995317 D 434271 CDS YP_001652843.1 165977250 5851133 complement(1996055..1997995) 1 NC_010278.1 ABC transporter ATP-binding protein 1997995 5851133 APJL_1849 Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC transporter ATP-binding protein YP_001652843.1 1996055 R 434271 CDS YP_001652844.1 165977251 5851481 complement(1997995..1999158) 1 NC_010278.1 hypothetical protein 1999158 5851481 APJL_1850 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652844.1 1997995 R 434271 CDS YP_001652845.1 165977252 5850792 complement(1999291..2000067) 1 NC_010278.1 putative outer membrane protein 2000067 5850792 APJL_1851 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative outer membrane protein YP_001652845.1 1999291 R 434271 CDS YP_001652846.1 165977253 5850923 complement(2000398..2001381) 1 NC_010278.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 2001381 holB 5850923 holB Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunit delta' YP_001652846.1 2000398 R 434271 CDS YP_001652847.1 165977254 5851444 complement(2001384..2002010) 1 NC_010278.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 2002010 tmk 5851444 tmk Actinobacillus pleuropneumoniae serovar 3 str. JL03 thymidylate kinase YP_001652847.1 2001384 R 434271 CDS YP_001652848.1 165977255 5851403 complement(2002014..2003048) 1 NC_010278.1 periplasmic solute-binding protein 2003048 5851403 APJL_1854 Actinobacillus pleuropneumoniae serovar 3 str. JL03 periplasmic solute-binding protein YP_001652848.1 2002014 R 434271 CDS YP_001652849.1 165977256 5851539 complement(2003646..2003951) 1 NC_010278.1 acyl carrier protein 2003951 acpP 5851539 acpP Actinobacillus pleuropneumoniae serovar 3 str. JL03 acyl carrier protein YP_001652849.1 2003646 R 434271 CDS YP_001652850.1 165977257 5851630 complement(2004143..2004817) 1 NC_010278.1 D-ribulose-phosphate-3 epimerase 2004817 rpe 5851630 rpe Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-ribulose-phosphate-3 epimerase YP_001652850.1 2004143 R 434271 CDS YP_001652851.1 165977258 5851618 2005039..2005308 1 NC_010278.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 2005308 rpmE2 5851618 rpmE2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L31 YP_001652851.1 2005039 D 434271 CDS YP_001652852.1 165977259 5851174 2005322..2005447 1 NC_010278.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 2005447 rpmJ 5851174 rpmJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L36 YP_001652852.1 2005322 D 434271 CDS YP_001652853.1 165977260 5851145 complement(2005552..2007954) 1 NC_010278.1 penicillin-binding protein 1B 2007954 ponB 5851145 ponB Actinobacillus pleuropneumoniae serovar 3 str. JL03 penicillin-binding protein 1B YP_001652853.1 2005552 R 434271 CDS YP_001652854.1 165977261 5850924 complement(2008033..2008890) 1 NC_010278.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2008890 menB 5850924 menB Actinobacillus pleuropneumoniae serovar 3 str. JL03 naphthoate synthase YP_001652854.1 2008033 R 434271 CDS YP_001652855.1 165977262 5851191 complement(2009025..2010731) 1 NC_010278.1 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 2010731 spoT 5851191 spoT Actinobacillus pleuropneumoniae serovar 3 str. JL03 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase YP_001652855.1 2009025 R 434271 CDS YP_001652856.1 165977263 5851195 complement(2010827..2011108) 1 NC_010278.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2011108 rpoZ 5851195 rpoZ Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-directed RNA polymerase subunit omega YP_001652856.1 2010827 R 434271 CDS YP_001652857.1 165977264 5851564 complement(2011235..2013316) 1 NC_010278.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 2013316 recG 5851564 recG Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent DNA helicase RecG YP_001652857.1 2011235 R 434271 CDS YP_001652858.1 165977265 5851241 complement(2013440..2013868) 1 NC_010278.1 PilT protein-like protein 2013868 5851241 APJL_1864 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PilT protein-like protein YP_001652858.1 2013440 R 434271 CDS YP_001652859.1 165977266 5851107 complement(2013868..2014155) 1 NC_010278.1 hypothetical protein 2014155 5851107 APJL_1865 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652859.1 2013868 R 434271 CDS YP_001652860.1 165977267 5851962 2014225..2014320 1 NC_010278.1 hypothetical protein 2014320 5851962 APJL_1866 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652860.1 2014225 D 434271 CDS YP_001652861.1 165977268 5850965 2014361..2016076 1 NC_010278.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 2016076 proS 5850965 proS Actinobacillus pleuropneumoniae serovar 3 str. JL03 prolyl-tRNA synthetase YP_001652861.1 2014361 D 434271 CDS YP_001652862.1 165977269 5851470 complement(2016142..2016330) 1 NC_010278.1 hypothetical protein 2016330 5851470 APJL_1868 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652862.1 2016142 R 434271 CDS YP_001652863.1 165977270 5851400 complement(2016333..2016914) 1 NC_010278.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 2016914 5851400 APJL_1869 Actinobacillus pleuropneumoniae serovar 3 str. JL03 RNA polymerase sigma factor YP_001652863.1 2016333 R 434271 CDS YP_001652864.1 165977271 5850712 2017003..2017959 1 NC_010278.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 2017959 5850712 APJL_1870 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sulfite oxidase subunit YedY YP_001652864.1 2017003 D 434271 CDS YP_001652865.1 165977272 5850898 2017959..2018552 1 NC_010278.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 2018552 5850898 APJL_1871 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative sulfite oxidase subunit YedZ YP_001652865.1 2017959 D 434271 CDS YP_001652866.1 165977273 5850983 complement(2018663..2019613) 1 NC_010278.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 2019613 rpoH 5850983 rpoH Actinobacillus pleuropneumoniae serovar 3 str. JL03 RNA polymerase factor sigma-32 YP_001652866.1 2018663 R 434271 CDS YP_001652867.1 165977274 5851608 complement(2019762..2021099) 1 NC_010278.1 sugar phosphate permease 2021099 5851608 APJL_1873 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sugar phosphate permease YP_001652867.1 2019762 R 434271 CDS YP_001652868.1 165977275 5851544 2021674..2022249 1 NC_010278.1 hypothetical protein 2022249 5851544 APJL_1874 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652868.1 2021674 D 434271 CDS YP_001652869.1 165977276 5851465 2022269..2022661 1 NC_010278.1 hypothetical protein 2022661 5851465 APJL_1875 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652869.1 2022269 D 434271 CDS YP_001652870.1 165977277 5851450 complement(2022704..2023696) 1 NC_010278.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 2023696 asnA 5851450 asnA Actinobacillus pleuropneumoniae serovar 3 str. JL03 asparagine synthetase AsnA YP_001652870.1 2022704 R 434271 CDS YP_001652871.1 165977278 5851556 2023878..2024339 1 NC_010278.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 2024339 asnC 5851556 asnC Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-binding transcriptional regulator AsnC YP_001652871.1 2023878 D 434271 CDS YP_001652872.1 165977279 5851114 2024528..2025292 1 NC_010278.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 2025292 udp 5851114 udp Actinobacillus pleuropneumoniae serovar 3 str. JL03 uridine phosphorylase YP_001652872.1 2024528 D 434271 CDS YP_001652873.1 165977280 5851441 2025356..2025850 1 NC_010278.1 4-hydroxybenzoate synthetase/chorismate--pyruvate lyase 2025850 ubiC 5851441 ubiC Actinobacillus pleuropneumoniae serovar 3 str. JL03 4-hydroxybenzoate synthetase/chorismate--pyruvate lyase YP_001652873.1 2025356 D 434271 CDS YP_001652874.1 165977281 5850776 2025923..2026720 1 NC_010278.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 2026720 murI 5850776 murI Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutamate racemase YP_001652874.1 2025923 D 434271 CDS YP_001652875.1 165977282 5851546 complement(2033112..2034878) 1 NC_010278.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 2034878 cysI 5851546 cysI Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfite reductase subunit beta YP_001652875.1 2033112 R 434271 CDS YP_001652876.1 165977283 5851542 complement(2034906..2036717) 1 NC_010278.1 sulfite reductase (NADPH) flavoprotein alpha-component 2036717 cysJ 5851542 cysJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfite reductase (NADPH) flavoprotein alpha-component YP_001652876.1 2034906 R 434271 CDS YP_001652877.1 165977284 5851462 complement(2037018..2038310) 1 NC_010278.1 sulfate adenylyltransferase 2038310 cysN 5851462 cysN Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfate adenylyltransferase YP_001652877.1 2037018 R 434271 CDS YP_001652878.1 165977285 5851411 complement(2038393..2039319) 1 NC_010278.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2039319 cysD 5851411 cysD Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfate adenylyltransferase subunit 2 YP_001652878.1 2038393 R 434271 CDS YP_001652879.1 165977286 5851958 complement(2039334..2040068) 1 NC_010278.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 2040068 cysH 5851958 cysH Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoadenosine phosphosulfate reductase YP_001652879.1 2039334 R 434271 CDS YP_001652880.1 165977287 5851879 complement(2040082..2041542) 1 NC_010278.1 uroporphyrinogen-III methylase 2041542 cysG 5851879 cysG Actinobacillus pleuropneumoniae serovar 3 str. JL03 uroporphyrinogen-III methylase YP_001652880.1 2040082 R 434271 CDS YP_001652881.1 165977288 5851735 2041817..2042809 1 NC_010278.1 sulfate-binding protein 2042809 sbp 5851735 sbp Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfate-binding protein YP_001652881.1 2041817 D 434271 CDS YP_001652882.1 165977289 5851891 2042828..2043640 1 NC_010278.1 sulfate ABC transporter permease 2043640 cysU 5851891 cysU Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfate ABC transporter permease YP_001652882.1 2042828 D 434271 CDS YP_001652883.1 165977290 5851828 2043659..2044474 1 NC_010278.1 sulfate ABC transporter permease 2044474 cysW 5851828 cysW Actinobacillus pleuropneumoniae serovar 3 str. JL03 sulfate ABC transporter permease YP_001652883.1 2043659 D 434271 CDS YP_001652884.1 165977291 5851825 2044485..2045555 1 NC_010278.1 ABC-type sulfate/molybdate transport systems, ATPase component 2045555 cysA 5851825 cysA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC-type sulfate/molybdate transport systems, ATPase component YP_001652884.1 2044485 D 434271 CDS YP_001652885.1 165977292 5851838 complement(2045644..2046789) 1 NC_010278.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 2046789 lldD 5851838 lldD Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-lactate dehydrogenase YP_001652885.1 2045644 R 434271 CDS YP_001652886.1 165977293 5851995 complement(2046973..2047737) 1 NC_010278.1 biotin operon represssor 2047737 birA 5851995 birA Actinobacillus pleuropneumoniae serovar 3 str. JL03 biotin operon represssor YP_001652886.1 2046973 R 434271 CDS YP_001652887.1 165977294 5851913 complement(2047746..2048780) 1 NC_010278.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 2048780 murB 5851913 murB Actinobacillus pleuropneumoniae serovar 3 str. JL03 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001652887.1 2047746 R 434271 CDS YP_001652888.1 165977295 5851926 complement(2048930..2050024) 1 NC_010278.1 major outer membrane protein 2050024 momP2 5851926 momP2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 major outer membrane protein YP_001652888.1 2048930 R 434271 CDS YP_001652889.1 165977296 5851981 2050442..2050951 1 NC_010278.1 transposase and inactivated derivative 2050951 5851981 APJL_1895 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001652889.1 2050442 D 434271 CDS YP_001652890.1 165977297 5851816 2050963..2051775 1 NC_010278.1 transposase 2051775 5851816 APJL_1896 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001652890.1 2050963 D 434271 CDS YP_001652891.1 165977298 5852027 complement(2051835..2053316) 1 NC_010278.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 2053316 ilvC 5852027 ilvC Actinobacillus pleuropneumoniae serovar 3 str. JL03 ketol-acid reductoisomerase YP_001652891.1 2051835 R 434271 CDS YP_001652892.1 165977299 5851876 2053553..2054794 1 NC_010278.1 PqiA protein 2054794 5851876 APJL_1898 Actinobacillus pleuropneumoniae serovar 3 str. JL03 PqiA protein YP_001652892.1 2053553 D 434271 CDS YP_001652893.1 165977300 5851835 2054971..2056071 1 NC_010278.1 hypothetical protein 2056071 5851835 APJL_1899 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652893.1 2054971 D 434271 CDS YP_001652894.1 165977301 5852003 2056043..2056396 1 NC_010278.1 putative mercuric transport protein 2056396 5852003 APJL_1900 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative mercuric transport protein YP_001652894.1 2056043 D 434271 CDS YP_001652895.1 165977302 5851997 2056393..2056707 1 NC_010278.1 copper chaperone 2056707 5851997 APJL_1901 Actinobacillus pleuropneumoniae serovar 3 str. JL03 copper chaperone YP_001652895.1 2056393 D 434271 CDS YP_001652896.1 165977303 5851890 complement(2056830..2058014) 1 NC_010278.1 NADH-dependent butanol dehydrogenase 1 2058014 5851890 APJL_1902 Actinobacillus pleuropneumoniae serovar 3 str. JL03 NADH-dependent butanol dehydrogenase 1 YP_001652896.1 2056830 R 434271 CDS YP_001652897.1 165977304 5851851 2058130..2059032 1 NC_010278.1 transcriptional regulator 2059032 5851851 APJL_1903 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652897.1 2058130 D 434271 CDS YP_001652898.1 165977305 5852850 2059236..2060060 1 NC_010278.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 2060060 dapD 5852850 dapD Actinobacillus pleuropneumoniae serovar 3 str. JL03 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001652898.1 2059236 D 434271 CDS YP_001652899.1 165977306 5852036 2060125..2060589 1 NC_010278.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 2060589 aroQ 5852036 aroQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-dehydroquinate dehydratase YP_001652899.1 2060125 D 434271 CDS YP_001652900.1 165977307 5852066 2060582..2061370 1 NC_010278.1 glycosyltransferase 2061370 5852066 APJL_1906 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycosyltransferase YP_001652900.1 2060582 D 434271 CDS YP_001652901.1 165977308 5852045 2061542..2062006 1 NC_010278.1 biotin carboxyl carrier protein ofacetyl-CoA carboxylase 2062006 accB 5852045 accB Actinobacillus pleuropneumoniae serovar 3 str. JL03 biotin carboxyl carrier protein ofacetyl-CoA carboxylase YP_001652901.1 2061542 D 434271 CDS YP_001652902.1 165977309 5852052 2062162..2063505 1 NC_010278.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 2063505 accC 5852052 accC Actinobacillus pleuropneumoniae serovar 3 str. JL03 acetyl-CoA carboxylase biotin carboxylase subunit YP_001652902.1 2062162 D 434271 CDS YP_001652903.1 165977310 5852054 complement(2063548..2064639) 1 NC_010278.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; MobB is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB 2064639 mobAB 5852054 mobAB Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB YP_001652903.1 2063548 R 434271 CDS YP_001652904.1 165977311 5852059 2064726..2064995 1 NC_010278.1 hypothetical protein 2064995 5852059 APJL_1910 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652904.1 2064726 D 434271 CDS YP_001652905.1 165977312 5852086 2065039..2065677 1 NC_010278.1 thiol:disulfide interchange protein 2065677 dsbA 5852086 dsbA Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol:disulfide interchange protein YP_001652905.1 2065039 D 434271 CDS YP_001652906.1 165977313 5852097 complement(2065769..2066035) 1 NC_010278.1 hypothetical protein 2066035 5852097 APJL_1912 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652906.1 2065769 R 434271 CDS YP_001652907.1 165977314 5852081 complement(2066148..2066354) 1 NC_010278.1 hypothetical protein 2066354 5852081 APJL_1913 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652907.1 2066148 R 434271 CDS YP_001652908.1 165977315 5852087 complement(2066457..2067380) 1 NC_010278.1 cell division protein 2067380 5852087 APJL_1914 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cell division protein YP_001652908.1 2066457 R 434271 CDS YP_001652909.1 165977316 5852098 complement(2067492..2068247) 1 NC_010278.1 hypothetical protein 2068247 5852098 APJL_1915 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652909.1 2067492 R 434271 CDS YP_001652910.1 165977317 5852793 complement(2068265..2068933) 1 NC_010278.1 D-alanyl-D-alanine carboxypeptidase 2068933 5852793 APJL_1916 Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-alanyl-D-alanine carboxypeptidase YP_001652910.1 2068265 R 434271 CDS YP_001652911.1 165977318 5852112 complement(2068952..2070085) 1 NC_010278.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2070085 dapE 5852112 dapE Actinobacillus pleuropneumoniae serovar 3 str. JL03 succinyl-diaminopimelate desuccinylase YP_001652911.1 2068952 R 434271 CDS YP_001652912.1 165977319 5852113 complement(2070108..2070458) 1 NC_010278.1 hypothetical protein 2070458 5852113 APJL_1918 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652912.1 2070108 R 434271 CDS YP_001652913.1 165977320 5852094 2070665..2071375 1 NC_010278.1 hypothetical protein 2071375 5852094 APJL_1919 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652913.1 2070665 D 434271 CDS YP_001652914.1 165977321 5852750 complement(2071426..2072271) 1 NC_010278.1 dihydropteroate synthase 2072271 folP 5852750 folP Actinobacillus pleuropneumoniae serovar 3 str. JL03 dihydropteroate synthase YP_001652914.1 2071426 R 434271 CDS YP_001652915.1 165977322 5852227 complement(2072333..2073298) 1 NC_010278.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 2073298 rluC 5852227 rluC Actinobacillus pleuropneumoniae serovar 3 str. JL03 23S rRNA pseudouridylate synthase C YP_001652915.1 2072333 R 434271 CDS YP_001652916.1 165977323 5852350 2073451..2076009 1 NC_010278.1 outer membrane receptor protein, mostly Fe transport 2076009 5852350 APJL_1922 Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane receptor protein, mostly Fe transport YP_001652916.1 2073451 D 434271 CDS YP_001652917.1 165977324 5852127 2076165..2077076 1 NC_010278.1 small-conductance mechanosensitive channel 2077076 5852127 APJL_1923 Actinobacillus pleuropneumoniae serovar 3 str. JL03 small-conductance mechanosensitive channel YP_001652917.1 2076165 D 434271 CDS YP_001652918.1 165977325 5852593 2077272..2078450 1 NC_010278.1 carbamoylphosphate synthase large subunit 2078450 5852593 APJL_1924 Actinobacillus pleuropneumoniae serovar 3 str. JL03 carbamoylphosphate synthase large subunit YP_001652918.1 2077272 D 434271 CDS YP_001652919.1 165977326 5852153 2078462..2079214 1 NC_010278.1 hypothetical protein 2079214 5852153 APJL_1925 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652919.1 2078462 D 434271 CDS YP_001652920.1 165977327 5852271 complement(2079282..2082242) 1 NC_010278.1 protease III 2082242 ptrA 5852271 ptrA Actinobacillus pleuropneumoniae serovar 3 str. JL03 protease III YP_001652920.1 2079282 R 434271 CDS YP_001652921.1 165977328 5852122 complement(2082239..2085583) 1 NC_010278.1 exodeoxyribonuclease V subunit gamma 2085583 recC 5852122 recC Actinobacillus pleuropneumoniae serovar 3 str. JL03 exodeoxyribonuclease V subunit gamma YP_001652921.1 2082239 R 434271 CDS YP_001652922.1 165977329 5852129 complement(2085688..2085984) 1 NC_010278.1 hypothetical protein 2085984 5852129 APJL_1928 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652922.1 2085688 R 434271 CDS YP_001652923.1 165977330 5852143 complement(2085974..2086630) 1 NC_010278.1 hypothetical protein 2086630 5852143 APJL_1929 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652923.1 2085974 R 434271 CDS YP_001652924.1 165977331 5852219 complement(2086640..2087338) 1 NC_010278.1 hypothetical protein 2087338 5852219 APJL_1930 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652924.1 2086640 R 434271 CDS YP_001652925.1 165977332 5852522 complement(2087298..2087828) 1 NC_010278.1 hypothetical protein 2087828 5852522 APJL_1931 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652925.1 2087298 R 434271 CDS YP_001652926.1 165977333 5852140 complement(2087916..2088446) 1 NC_010278.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 2088446 fabA 5852140 fabA Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-hydroxydecanoyl-ACP dehydratase YP_001652926.1 2087916 R 434271 CDS YP_001652927.1 165977334 5852149 complement(2088557..2090194) 1 NC_010278.1 lon protease 2090194 lonH 5852149 lonH Actinobacillus pleuropneumoniae serovar 3 str. JL03 lon protease YP_001652927.1 2088557 R 434271 CDS YP_001652928.1 165977335 5852136 2090279..2090725 1 NC_010278.1 hypothetical protein 2090725 5852136 APJL_1934 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652928.1 2090279 D 434271 CDS YP_001652929.1 165977336 5852145 complement(2090797..2091825) 1 NC_010278.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 2091825 trpS 5852145 trpS Actinobacillus pleuropneumoniae serovar 3 str. JL03 tryptophanyl-tRNA synthetase YP_001652929.1 2090797 R 434271 CDS YP_001652930.1 165977337 5852152 complement(2091965..2092630) 1 NC_010278.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 2092630 gph 5852152 gph Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoglycolate phosphatase YP_001652930.1 2091965 R 434271 CDS YP_001652931.1 165977338 5852154 complement(2092800..2092991) 1 NC_010278.1 hypothetical protein 2092991 5852154 APJL_1937 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652931.1 2092800 R 434271 CDS YP_001652932.1 165977339 5852183 complement(2093189..2093983) 1 NC_010278.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 2093983 lgt 5852183 lgt Actinobacillus pleuropneumoniae serovar 3 str. JL03 prolipoprotein diacylglyceryl transferase YP_001652932.1 2093189 R 434271 CDS YP_001652933.1 165977340 5852264 complement(2094036..2094827) 1 NC_010278.1 permease 2094827 5852264 APJL_1939 Actinobacillus pleuropneumoniae serovar 3 str. JL03 permease YP_001652933.1 2094036 R 434271 CDS YP_001652934.1 165977341 5852319 complement(2094824..2095444) 1 NC_010278.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 2095444 nudH 5852319 nudH Actinobacillus pleuropneumoniae serovar 3 str. JL03 dinucleoside polyphosphate hydrolase YP_001652934.1 2094824 R 434271 CDS YP_001652935.1 165977342 5852332 2095483..2095647 1 NC_010278.1 hypothetical protein 2095647 5852332 APJL_1941 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652935.1 2095483 D 434271 CDS YP_001652936.1 165977343 5852409 complement(2095989..2096756) 1 NC_010278.1 Zn-dependent protease with chaperone function 2096756 5852409 APJL_1942 Actinobacillus pleuropneumoniae serovar 3 str. JL03 Zn-dependent protease with chaperone function YP_001652936.1 2095989 R 434271 CDS YP_001652937.1 165977344 5852474 complement(2096852..2097379) 1 NC_010278.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 2097379 ppa 5852474 ppa Actinobacillus pleuropneumoniae serovar 3 str. JL03 inorganic pyrophosphatase YP_001652937.1 2096852 R 434271 CDS YP_001652938.1 165977345 5852261 complement(2098209..2098706) 1 NC_010278.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 2098706 menG 5852261 menG Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease activity regulator protein RraA YP_001652938.1 2098209 R 434271 CDS YP_001652939.1 165977346 5852641 2099009..2099719 1 NC_010278.1 putative formate-nitrite transporter 2099719 yrhG 5852641 yrhG Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative formate-nitrite transporter YP_001652939.1 2099009 D 434271 CDS YP_001652940.1 165977347 5852705 2099890..2100714 1 NC_010278.1 hypothetical protein 2100714 5852705 APJL_1948 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652940.1 2099890 D 434271 CDS YP_001652941.1 165977348 5852161 complement(2100862..2101674) 1 NC_010278.1 transposase 2101674 5852161 APJL_1949 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase YP_001652941.1 2100862 R 434271 CDS YP_001652942.1 165977349 5852676 complement(2101686..2102195) 1 NC_010278.1 transposase and inactivated derivative 2102195 5852676 APJL_1950 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase and inactivated derivative YP_001652942.1 2101686 R 434271 CDS YP_001652943.1 165977350 5852210 complement(2102188..2103042) 1 NC_010278.1 hypothetical protein 2103042 5852210 APJL_1951 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652943.1 2102188 R 434271 CDS YP_001652944.1 165977351 5852738 complement(2103301..2104443) 1 NC_010278.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 2104443 dnaJ 5852738 dnaJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 chaperone protein DnaJ YP_001652944.1 2103301 R 434271 CDS YP_001652945.1 165977352 5852606 complement(2104582..2106483) 1 NC_010278.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 2106483 dnaK 5852606 dnaK Actinobacillus pleuropneumoniae serovar 3 str. JL03 molecular chaperone DnaK YP_001652945.1 2104582 R 434271 CDS YP_001652946.1 165977353 5852818 complement(2106758..2108203) 1 NC_010278.1 sugar (pentulose and hexulose) kinase 2108203 xylB2 5852818 xylB2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 sugar (pentulose and hexulose) kinase YP_001652946.1 2106758 R 434271 CDS YP_001652947.1 165977354 5852797 complement(2108401..2109720) 1 NC_010278.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 2109720 xylA 5852797 xylA Actinobacillus pleuropneumoniae serovar 3 str. JL03 xylose isomerase YP_001652947.1 2108401 R 434271 CDS YP_001652948.1 165977355 5852790 2109974..2110972 1 NC_010278.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 2110972 xylF 5852790 xylF Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-xylose transporter subunit XylF YP_001652948.1 2109974 D 434271 CDS YP_001652949.1 165977356 5851804 2111036..2112550 1 NC_010278.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 2112550 xylG 5851804 xylG Actinobacillus pleuropneumoniae serovar 3 str. JL03 xylose transporter ATP-binding subunit YP_001652949.1 2111036 D 434271 CDS YP_001652950.1 165977357 5851938 2112554..2113681 1 NC_010278.1 D-xylose transport system permease 2113681 xylH 5851938 xylH Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-xylose transport system permease YP_001652950.1 2112554 D 434271 CDS YP_001652951.1 165977358 5851741 2113806..2114987 1 NC_010278.1 transcriptional regulator 2114987 purR3 5851741 purR3 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional regulator YP_001652951.1 2113806 D 434271 CDS YP_001652952.1 165977359 5851766 2114992..2117019 1 NC_010278.1 metallopeptidase 2117019 pepO 5851766 pepO Actinobacillus pleuropneumoniae serovar 3 str. JL03 metallopeptidase YP_001652952.1 2114992 D 434271 CDS YP_001652953.1 165977360 5852078 2117094..2117321 1 NC_010278.1 hypothetical protein 2117321 5852078 APJL_1961 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652953.1 2117094 D 434271 CDS YP_001652954.1 165977361 5851368 complement(2117390..2118802) 1 NC_010278.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 2118802 panF 5851368 panF Actinobacillus pleuropneumoniae serovar 3 str. JL03 sodium/panthothenate symporter YP_001652954.1 2117390 R 434271 CDS YP_001652955.1 165977362 5851530 complement(2118822..2119046) 1 NC_010278.1 hypothetical protein 2119046 5851530 APJL_1963 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652955.1 2118822 R 434271 CDS YP_001652956.1 165977363 5852309 complement(2119098..2119415) 1 NC_010278.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 2119415 metJ 5852309 metJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 transcriptional repressor protein MetJ YP_001652956.1 2119098 R 434271 CDS YP_001652957.1 165977364 5852034 2119584..2120333 1 NC_010278.1 VacJ lipoprotein 2120333 vacJ 5852034 vacJ Actinobacillus pleuropneumoniae serovar 3 str. JL03 VacJ lipoprotein YP_001652957.1 2119584 D 434271 CDS YP_001652958.1 165977365 5851445 2120408..2121217 1 NC_010278.1 hypothetical protein 2121217 5851445 APJL_1966 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652958.1 2120408 D 434271 CDS YP_001652959.1 165977366 5851010 2121342..2123309 1 NC_010278.1 site-specific recombinase 2123309 5851010 APJL_1967 Actinobacillus pleuropneumoniae serovar 3 str. JL03 site-specific recombinase YP_001652959.1 2121342 D 434271 CDS YP_001652960.1 165977367 5851378 2124055..2126547 1 NC_010278.1 biofilm PGA synthesis protein PgaA 2126547 pgaA 5851378 pgaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 biofilm PGA synthesis protein PgaA YP_001652960.1 2124055 D 434271 CDS YP_001652961.1 165977368 5850743 2126562..2128334 1 NC_010278.1 biofilm PGA synthesis lipoprotein PgaB 2128334 pgaB 5850743 pgaB Actinobacillus pleuropneumoniae serovar 3 str. JL03 biofilm PGA synthesis lipoprotein PgaB YP_001652961.1 2126562 D 434271 CDS YP_001652962.1 165977369 5850972 2128343..2129524 1 NC_010278.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 2129524 pgaC 5850972 pgaC Actinobacillus pleuropneumoniae serovar 3 str. JL03 N-glycosyltransferase YP_001652962.1 2128343 D 434271 CDS YP_001652963.1 165977370 5851322 2129526..2129810 1 NC_010278.1 FOG: WD40 repeat; biofilm PGA synthesis protein 2129810 pgaD 5851322 pgaD Actinobacillus pleuropneumoniae serovar 3 str. JL03 biofilm PGA synthesis protein YP_001652963.1 2129526 D 434271 CDS YP_001652964.1 165977371 5851232 complement(2129914..2130684) 1 NC_010278.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 2130684 tpiA 5851232 tpiA Actinobacillus pleuropneumoniae serovar 3 str. JL03 triosephosphate isomerase YP_001652964.1 2129914 R 434271 CDS YP_001652965.1 165977372 5851549 2130959..2131972 1 NC_010278.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 2131972 truD 5851549 truD Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA pseudouridine synthase D YP_001652965.1 2130959 D 434271 CDS YP_001652966.1 165977373 5851272 2131972..2132736 1 NC_010278.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 2132736 surE 5851272 surE Actinobacillus pleuropneumoniae serovar 3 str. JL03 stationary phase survival protein SurE YP_001652966.1 2131972 D 434271 CDS YP_001652967.1 165977374 5850861 2132736..2133320 1 NC_010278.1 hypothetical protein 2133320 5850861 APJL_1975 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652967.1 2132736 D 434271 CDS YP_001652968.1 165977375 5851059 2133332..2133907 1 NC_010278.1 lipoprotein 2133907 5851059 APJL_1976 Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein YP_001652968.1 2133332 D 434271 CDS YP_001652969.1 165977376 5850954 2133993..2134190 1 NC_010278.1 hypothetical protein 2134190 5850954 APJL_1977 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652969.1 2133993 D 434271 CDS YP_001652970.1 165977377 5851473 2134266..2135462 1 NC_010278.1 outer membrane antigenic lipoprotein B 2135462 lppB 5851473 lppB Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane antigenic lipoprotein B YP_001652970.1 2134266 D 434271 CDS YP_001652971.1 165977378 5851283 2135551..2136114 1 NC_010278.1 DNA-3-methyladenine glycosidase I 2136114 tagI 5851283 tagI Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA-3-methyladenine glycosidase I YP_001652971.1 2135551 D 434271 CDS YP_001652972.1 165977379 5850865 complement(2136166..2137293) 1 NC_010278.1 carboxypeptidase G2 2137293 5850865 APJL_1980 Actinobacillus pleuropneumoniae serovar 3 str. JL03 carboxypeptidase G2 YP_001652972.1 2136166 R 434271 CDS YP_001652973.1 165977380 5850936 complement(2137307..2137771) 1 NC_010278.1 hypothetical protein 2137771 5850936 APJL_1981 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652973.1 2137307 R 434271 CDS YP_001652974.1 165977381 5851497 complement(2137768..2138406) 1 NC_010278.1 hypothetical protein 2138406 5851497 APJL_1982 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652974.1 2137768 R 434271 CDS YP_001652975.1 165977382 5851505 complement(2138583..2139542) 1 NC_010278.1 protoheme ferro-lyase 2139542 hemH 5851505 hemH Actinobacillus pleuropneumoniae serovar 3 str. JL03 protoheme ferro-lyase YP_001652975.1 2138583 R 434271 CDS YP_001652976.1 165977383 5850724 2139818..2139952 1 NC_010278.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 2139952 rpmH 5850724 rpmH Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L34 YP_001652976.1 2139818 D 434271 CDS YP_001652977.1 165977384 5851504 2140018..2140350 1 NC_010278.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 2140350 rnpA 5851504 rnpA Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease P YP_001652977.1 2140018 D 434271 CDS YP_001652978.1 165977385 5851126 2140377..2140613 1 NC_010278.1 hypothetical protein 2140613 5851126 APJL_1986 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652978.1 2140377 D 434271 CDS YP_001652979.1 165977386 5851043 complement(2140664..2142079) 1 NC_010278.1 glutamine synthetase 2142079 glnA 5851043 glnA Actinobacillus pleuropneumoniae serovar 3 str. JL03 glutamine synthetase YP_001652979.1 2140664 R 434271 CDS YP_001652980.1 165977387 5851479 complement(2142437..2143264) 1 NC_010278.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 2143264 icc 5851479 icc Actinobacillus pleuropneumoniae serovar 3 str. JL03 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_001652980.1 2142437 R 434271 CDS YP_001652981.1 165977388 5851562 complement(2143471..2144094) 1 NC_010278.1 putative ADP-ribose pyrophosphatase 2144094 5851562 APJL_1989 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative ADP-ribose pyrophosphatase YP_001652981.1 2143471 R 434271 CDS YP_001652982.1 165977389 5851629 complement(2144104..2144523) 1 NC_010278.1 phosphate-starvation-inducible protein PsiE 2144523 psiE2 5851629 psiE2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphate-starvation-inducible protein PsiE YP_001652982.1 2144104 R 434271 CDS YP_001652983.1 165977390 5851345 complement(2144516..2145244) 1 NC_010278.1 putative 4'-phosphopantetheinyl transferase 2145244 5851345 APJL_1991 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative 4'-phosphopantetheinyl transferase YP_001652983.1 2144516 R 434271 CDS YP_001652984.1 165977391 5851120 complement(2145304..2145732) 1 NC_010278.1 integral membrane protein 2145732 5851120 APJL_1992 Actinobacillus pleuropneumoniae serovar 3 str. JL03 integral membrane protein YP_001652984.1 2145304 R 434271 CDS YP_001652985.1 165977392 5851380 complement(2145735..2145911) 1 NC_010278.1 hypothetical protein 2145911 5851380 APJL_1993 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652985.1 2145735 R 434271 CDS YP_001652986.1 165977393 5851631 2145910..2147094 1 NC_010278.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 2147094 nhaA 5851631 nhaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 pH-dependent sodium/proton antiporter YP_001652986.1 2145910 D 434271 CDS YP_001652987.1 165977394 5851159 2147237..2147725 1 NC_010278.1 hypothetical protein 2147725 5851159 APJL_1995 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652987.1 2147237 D 434271 CDS YP_001652988.1 165977395 5851202 complement(2147761..2148195) 1 NC_010278.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2148195 dtd 5851202 dtd Actinobacillus pleuropneumoniae serovar 3 str. JL03 D-tyrosyl-tRNA(Tyr) deacylase YP_001652988.1 2147761 R 434271 CDS YP_001652989.1 165977396 5851095 complement(2148192..2149022) 1 NC_010278.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 2149022 rbn 5851095 rbn Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribonuclease BN YP_001652989.1 2148192 R 434271 CDS YP_001652990.1 165977397 5850958 complement(2149040..2150278) 1 NC_010278.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 2150278 proA 5850958 proA Actinobacillus pleuropneumoniae serovar 3 str. JL03 gamma-glutamyl phosphate reductase YP_001652990.1 2149040 R 434271 CDS YP_001652991.1 165977398 5851119 2150479..2150658 1 NC_010278.1 hypothetical protein 2150658 5851119 APJL_1999 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652991.1 2150479 D 434271 CDS YP_001652992.1 165977399 5851288 complement(2153027..2153881) 1 NC_010278.1 hypothetical protein 2153881 5851288 APJL_2003 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652992.1 2153027 R 434271 CDS YP_001652993.1 165977400 5851632 complement(2154000..2155244) 1 NC_010278.1 hypothetical protein 2155244 5851632 APJL_2004 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652993.1 2154000 R 434271 CDS YP_001652994.1 165977401 5851001 2155558..2157426 1 NC_010278.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 2157426 mutL 5851001 mutL Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA mismatch repair protein YP_001652994.1 2155558 D 434271 CDS YP_001652995.1 165977402 5851551 2157626..2158675 1 NC_010278.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 2158675 adh3 5851551 adh3 Actinobacillus pleuropneumoniae serovar 3 str. JL03 alcohol dehydrogenase YP_001652995.1 2157626 D 434271 CDS YP_001652996.1 165977403 5851372 2158807..2159751 1 NC_010278.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 2159751 miaA 5851372 miaA Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001652996.1 2158807 D 434271 CDS YP_001652997.1 165977404 5850981 2159816..2160094 1 NC_010278.1 host factor-I protein Hfq 2160094 hfq 5850981 hfq Actinobacillus pleuropneumoniae serovar 3 str. JL03 host factor-I protein Hfq YP_001652997.1 2159816 D 434271 CDS YP_001652998.1 165977405 5851469 2160426..2161499 1 NC_010278.1 GTP-binding protein HflX 2161499 hflX 5851469 hflX Actinobacillus pleuropneumoniae serovar 3 str. JL03 GTP-binding protein HflX YP_001652998.1 2160426 D 434271 CDS YP_001652999.1 165977406 5851458 complement(2161535..2162095) 1 NC_010278.1 hypothetical protein 2162095 5851458 APJL_2010 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001652999.1 2161535 R 434271 CDS YP_001653000.1 165977407 5850930 2162158..2162481 1 NC_010278.1 pyrophosphatase 2162481 5850930 APJL_2011 Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyrophosphatase YP_001653000.1 2162158 D 434271 CDS YP_001653001.1 165977408 5851248 complement(2162530..2163210) 1 NC_010278.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 2163210 5851248 APJL_2012 Actinobacillus pleuropneumoniae serovar 3 str. JL03 cAMP-regulatory protein YP_001653001.1 2162530 R 434271 CDS YP_001653002.1 165977409 5850920 complement(2163282..2163500) 1 NC_010278.1 hypothetical protein 2163500 5850920 APJL_2013 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653002.1 2163282 R 434271 CDS YP_001653003.1 165977410 5850784 complement(2163506..2164114) 1 NC_010278.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 2164114 slmA 5850784 slmA Actinobacillus pleuropneumoniae serovar 3 str. JL03 nucleoid occlusion protein YP_001653003.1 2163506 R 434271 CDS YP_001653004.1 165977411 5851012 complement(2164220..2164675) 1 NC_010278.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 2164675 dut 5851012 dut Actinobacillus pleuropneumoniae serovar 3 str. JL03 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001653004.1 2164220 R 434271 CDS YP_001653005.1 165977412 5851066 complement(2164684..2165889) 1 NC_010278.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 2165889 dfp 5851066 dfp Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001653005.1 2164684 R 434271 CDS YP_001653006.1 165977413 5850943 2166097..2166759 1 NC_010278.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 2166759 radC 5850943 radC Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA repair protein RadC YP_001653006.1 2166097 D 434271 CDS YP_001653007.1 165977414 5851643 2166928..2167164 1 NC_010278.1 required for 70S ribosome assembly; 50S ribosomal protein L28 2167164 rpmB 5851643 rpmB Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L28 YP_001653007.1 2166928 D 434271 CDS YP_001653008.1 165977415 5850741 2167176..2167346 1 NC_010278.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2167346 rpmG 5850741 rpmG Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L33 YP_001653008.1 2167176 D 434271 CDS YP_001653009.1 165977416 5851435 2167497..2167682 1 NC_010278.1 hypothetical protein 2167682 5851435 APJL_2020 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653009.1 2167497 D 434271 CDS YP_001653010.1 165977417 5851212 2167711..2168271 1 NC_010278.1 hypothetical protein 2168271 5851212 APJL_2021 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653010.1 2167711 D 434271 CDS YP_001653011.1 165977418 5850716 complement(2168283..2168459) 1 NC_010278.1 hypothetical protein 2168459 5850716 APJL_2022 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653011.1 2168283 R 434271 CDS YP_001653012.1 165977419 5851209 2168621..2169916 1 NC_010278.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 2169916 argD1 5851209 argD1 Actinobacillus pleuropneumoniae serovar 3 str. JL03 diaminobutyrate--2-oxoglutarate aminotransferase YP_001653012.1 2168621 D 434271 CDS YP_001653013.1 165977420 5850980 2170045..2171580 1 NC_010278.1 L-2,4-diaminobutyrate decarboxylase 2171580 ddc 5850980 ddc Actinobacillus pleuropneumoniae serovar 3 str. JL03 L-2,4-diaminobutyrate decarboxylase YP_001653013.1 2170045 D 434271 CDS YP_001653014.1 165977421 5851068 complement(2171639..2171908) 1 NC_010278.1 hypothetical protein 2171908 5851068 APJL_2025 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653014.1 2171639 R 434271 CDS YP_001653015.1 165977422 5851633 complement(2171926..2173146) 1 NC_010278.1 putative inner membrane protein 2173146 5851633 APJL_2026 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative inner membrane protein YP_001653015.1 2171926 R 434271 CDS YP_001653016.1 165977423 5850901 2173442..2173774 1 NC_010278.1 hypothetical protein 2173774 5850901 APJL_2027 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653016.1 2173442 D 434271 CDS YP_001653017.1 165977424 5850814 2173937..2175043 1 NC_010278.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 2175043 trmA2 5850814 trmA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 tRNA (uracil-5-)-methyltransferase YP_001653017.1 2173937 D 434271 CDS YP_001653018.1 165977425 5851626 complement(2175544..2176497) 1 NC_010278.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 2176497 corA 5851626 corA Actinobacillus pleuropneumoniae serovar 3 str. JL03 magnesium/nickel/cobalt transporter CorA YP_001653018.1 2175544 R 434271 CDS YP_001653019.1 165977426 5851636 2176798..2177574 1 NC_010278.1 ubiquinone/menaquinone biosynthesis methyltransferase 2177574 ubiE 5851636 ubiE Actinobacillus pleuropneumoniae serovar 3 str. JL03 ubiquinone/menaquinone biosynthesis methyltransferase YP_001653019.1 2176798 D 434271 CDS YP_001653020.1 165977427 5851304 2177610..2178242 1 NC_010278.1 hypothetical protein 2178242 5851304 APJL_2031 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653020.1 2177610 D 434271 CDS YP_001653021.1 165977428 5850742 2178239..2179873 1 NC_010278.1 ubiquinone biosynthesis protein 2179873 ubiB 5850742 ubiB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ubiquinone biosynthesis protein YP_001653021.1 2178239 D 434271 CDS YP_001653022.1 165977429 5851026 2179965..2180195 1 NC_010278.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 2180195 tatA 5851026 tatA Actinobacillus pleuropneumoniae serovar 3 str. JL03 twin arginine translocase protein A YP_001653022.1 2179965 D 434271 CDS YP_001653023.1 165977430 5851025 2180199..2180786 1 NC_010278.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 2180786 tatB 5851025 tatB Actinobacillus pleuropneumoniae serovar 3 str. JL03 sec-independent translocase YP_001653023.1 2180199 D 434271 CDS YP_001653024.1 165977431 5851069 2180950..2181522 1 NC_010278.1 sec-independent protein secretion pathway component 2181522 tatC 5851069 tatC Actinobacillus pleuropneumoniae serovar 3 str. JL03 sec-independent protein secretion pathway component YP_001653024.1 2180950 D 434271 CDS YP_001653025.1 165977432 5851149 2181582..2182601 1 NC_010278.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2182601 hemB 5851149 hemB Actinobacillus pleuropneumoniae serovar 3 str. JL03 delta-aminolevulinic acid dehydratase YP_001653025.1 2181582 D 434271 CDS YP_001653026.1 165977433 5851077 2182688..2183050 1 NC_010278.1 hypothetical protein 2183050 5851077 APJL_2037 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653026.1 2182688 D 434271 CDS YP_001653027.1 165977434 5850907 complement(2183101..2183922) 1 NC_010278.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 2183922 mutM 5850907 mutM Actinobacillus pleuropneumoniae serovar 3 str. JL03 formamidopyrimidine-DNA glycosylase YP_001653027.1 2183101 R 434271 CDS YP_001653028.1 165977435 5851877 complement(2183985..2185277) 1 NC_010278.1 branched-chain amino acid permease 2185277 brnQ 5851877 brnQ Actinobacillus pleuropneumoniae serovar 3 str. JL03 branched-chain amino acid permease YP_001653028.1 2183985 R 434271 CDS YP_001653029.1 165977436 5852018 complement(2185403..2186128) 1 NC_010278.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2186128 fabG 5852018 fabG Actinobacillus pleuropneumoniae serovar 3 str. JL03 3-ketoacyl-ACP reductase YP_001653029.1 2185403 R 434271 CDS YP_001653030.1 165977437 5852021 complement(2186246..2187181) 1 NC_010278.1 malonyl CoA-acyl carrier protein transacylase 2187181 fabD 5852021 fabD Actinobacillus pleuropneumoniae serovar 3 str. JL03 malonyl CoA-acyl carrier protein transacylase YP_001653030.1 2186246 R 434271 CDS YP_001653031.1 165977438 5851930 complement(2187248..2187994) 1 NC_010278.1 hypothetical protein 2187994 5851930 APJL_2042 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653031.1 2187248 R 434271 CDS YP_001653032.1 165977439 5851904 complement(2188031..2189026) 1 NC_010278.1 octaprenyl-diphosphate synthase 2189026 ispB 5851904 ispB Actinobacillus pleuropneumoniae serovar 3 str. JL03 octaprenyl-diphosphate synthase YP_001653032.1 2188031 R 434271 CDS YP_001653033.1 165977440 5851770 2189315..2190133 1 NC_010278.1 hypothetical protein 2190133 5851770 APJL_2044 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653033.1 2189315 D 434271 CDS YP_001653034.1 165977441 5851824 2190297..2190848 1 NC_010278.1 flavoprotein 2190848 5851824 APJL_2045 Actinobacillus pleuropneumoniae serovar 3 str. JL03 flavoprotein YP_001653034.1 2190297 D 434271 CDS YP_001653035.1 165977442 5851817 2191049..2191462 1 NC_010278.1 hypothetical protein 2191462 5851817 APJL_2046 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653035.1 2191049 D 434271 CDS YP_001653036.1 165977443 5852026 2191791..2192126 1 NC_010278.1 50S ribosomal protein L21 2192126 rplU 5852026 rplU Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L21 YP_001653036.1 2191791 D 434271 CDS YP_001653037.1 165977444 5851821 2192147..2192404 1 NC_010278.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 2192404 rpmA 5851821 rpmA Actinobacillus pleuropneumoniae serovar 3 str. JL03 50S ribosomal protein L27 YP_001653037.1 2192147 D 434271 CDS YP_001653038.1 165977445 5851818 2192439..2193428 1 NC_010278.1 putative transport protein 2193428 5851818 APJL_2049 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative transport protein YP_001653038.1 2192439 D 434271 CDS YP_001653039.1 165977446 5852031 2193425..2193595 1 NC_010278.1 hypothetical protein 2193595 5852031 APJL_2050 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653039.1 2193425 D 434271 CDS YP_001653040.1 165977447 5851840 complement(2193657..2195126) 1 NC_010278.1 hypothetical protein 2195126 5851840 APJL_2051 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653040.1 2193657 R 434271 CDS YP_001653041.1 165977448 5851867 complement(2195242..2196051) 1 NC_010278.1 HAD superfamily hydrolase 2196051 5851867 APJL_2052 Actinobacillus pleuropneumoniae serovar 3 str. JL03 HAD superfamily hydrolase YP_001653041.1 2195242 R 434271 CDS YP_001653042.1 165977449 5852029 2196026..2196178 1 NC_010278.1 hypothetical protein 2196178 5852029 APJL_2053 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653042.1 2196026 D 434271 CDS YP_001653043.1 165977450 5851845 2196171..2196848 1 NC_010278.1 competence protein F 2196848 comF 5851845 comF Actinobacillus pleuropneumoniae serovar 3 str. JL03 competence protein F YP_001653043.1 2196171 D 434271 CDS YP_001653044.1 165977451 5851672 complement(2197283..2198272) 1 NC_010278.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 2198272 rsmC 5851672 rsmC Actinobacillus pleuropneumoniae serovar 3 str. JL03 16S ribosomal RNA m2G1207 methyltransferase YP_001653044.1 2197283 R 434271 CDS YP_001653045.1 165977452 5851986 2198407..2198799 1 NC_010278.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 2198799 holD 5851986 holD Actinobacillus pleuropneumoniae serovar 3 str. JL03 DNA polymerase III subunit psi YP_001653045.1 2198407 D 434271 CDS YP_001653046.1 165977453 5851515 2198792..2199229 1 NC_010278.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 2199229 rimI 5851515 rimI Actinobacillus pleuropneumoniae serovar 3 str. JL03 ribosomal-protein-alanine N-acetyltransferase YP_001653046.1 2198792 D 434271 CDS YP_001653047.1 165977454 5851886 2199252..2200601 1 NC_010278.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2200601 srmB 5851886 srmB Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP-dependent RNA helicase SrmB YP_001653047.1 2199252 D 434271 CDS YP_001653048.1 165977455 5851698 2200679..2201308 1 NC_010278.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2201308 pdxH 5851698 pdxH Actinobacillus pleuropneumoniae serovar 3 str. JL03 pyridoxamine 5'-phosphate oxidase YP_001653048.1 2200679 D 434271 CDS YP_001653049.1 165977456 5851924 complement(2201377..2203014) 1 NC_010278.1 heme-binding protein A 2203014 hbpA2 5851924 hbpA2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 heme-binding protein A YP_001653049.1 2201377 R 434271 CDS YP_001653050.1 165977457 5851711 complement(2203205..2204686) 1 NC_010278.1 putative aldehyde dehydrogenase 2204686 aldA 5851711 aldA Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative aldehyde dehydrogenase YP_001653050.1 2203205 R 434271 CDS YP_001653051.1 165977458 5852010 complement(2204892..2205461) 1 NC_010278.1 inner membrane protein 2205461 5852010 APJL_2062 Actinobacillus pleuropneumoniae serovar 3 str. JL03 inner membrane protein YP_001653051.1 2204892 R 434271 CDS YP_001653052.1 165977459 5852827 2205703..2206467 1 NC_010278.1 ABC-type cobalamin/Fe3+-siderophores transportsystems, ATPase components 2206467 fhuC 5852827 fhuC Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABC-type cobalamin/Fe3+-siderophores transportsystems, ATPase components YP_001653052.1 2205703 D 434271 CDS YP_001653053.1 165977460 5852011 2206467..2207423 1 NC_010278.1 ferrichrome-binding periplasmic protein 2207423 fhuD 5852011 fhuD Actinobacillus pleuropneumoniae serovar 3 str. JL03 ferrichrome-binding periplasmic protein YP_001653053.1 2206467 D 434271 CDS YP_001653054.1 165977461 5852024 2207417..2209369 1 NC_010278.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 2209369 fhuB 5852024 fhuB Actinobacillus pleuropneumoniae serovar 3 str. JL03 iron-hydroxamate transporter permease subunit YP_001653054.1 2207417 D 434271 CDS YP_001653055.1 165977462 5851905 2209416..2211503 1 NC_010278.1 outer membrane ferric hydroxamate receptor 2211503 fhuA 5851905 fhuA Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane ferric hydroxamate receptor YP_001653055.1 2209416 D 434271 CDS YP_001653056.1 165977463 5851190 2211570..2211887 1 NC_010278.1 hypothetical protein 2211887 5851190 APJL_2067 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653056.1 2211570 D 434271 CDS YP_001653057.1 165977464 5852014 complement(2211978..2212835) 1 NC_010278.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2212835 purC 5852014 purC Actinobacillus pleuropneumoniae serovar 3 str. JL03 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001653057.1 2211978 R 434271 CDS YP_001653058.1 165977465 5852071 2213204..2214103 1 NC_010278.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2214103 hisG 5852071 hisG Actinobacillus pleuropneumoniae serovar 3 str. JL03 ATP phosphoribosyltransferase YP_001653058.1 2213204 D 434271 CDS YP_001653059.1 165977466 5852057 2214219..2215505 1 NC_010278.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2215505 hisD 5852057 hisD Actinobacillus pleuropneumoniae serovar 3 str. JL03 histidinol dehydrogenase YP_001653059.1 2214219 D 434271 CDS YP_001653060.1 165977467 5852080 2215629..2216681 1 NC_010278.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2216681 hisC2 5852080 hisC2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 histidinol-phosphate aminotransferase YP_001653060.1 2215629 D 434271 CDS YP_001653061.1 165977468 5851682 2216792..2217085 1 NC_010278.1 transposase IS200-like protein 2217085 5851682 APJL_2072 Actinobacillus pleuropneumoniae serovar 3 str. JL03 transposase IS200-like protein YP_001653061.1 2216792 D 434271 CDS YP_001653062.1 165977469 5852099 2217207..2218292 1 NC_010278.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2218292 hisB 5852099 hisB Actinobacillus pleuropneumoniae serovar 3 str. JL03 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_001653062.1 2217207 D 434271 CDS YP_001653063.1 165977470 5852084 2218634..2219587 1 NC_010278.1 hypothetical protein 2219587 5852084 APJL_2074 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653063.1 2218634 D 434271 CDS YP_001653064.1 165977471 5852109 2219604..2220197 1 NC_010278.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2220197 hisH 5852109 hisH Actinobacillus pleuropneumoniae serovar 3 str. JL03 imidazole glycerol phosphate synthase subunit HisH YP_001653064.1 2219604 D 434271 CDS YP_001653065.1 165977472 5852115 2220318..2221070 1 NC_010278.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2221070 hisA 5852115 hisA Actinobacillus pleuropneumoniae serovar 3 str. JL03 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_001653065.1 2220318 D 434271 CDS YP_001653066.2 229597127 5852117 2221052..2221825 1 NC_010278.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2221825 hisF 5852117 hisF Actinobacillus pleuropneumoniae serovar 3 str. JL03 imidazole glycerol phosphate synthase subunit HisF YP_001653066.2 2221052 D 434271 CDS YP_001653067.1 165977474 5852079 2221954..2222598 1 NC_010278.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2222598 hisI 5852079 hisI Actinobacillus pleuropneumoniae serovar 3 str. JL03 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_001653067.1 2221954 D 434271 CDS YP_001653068.1 165977475 5852039 2222719..2223384 1 NC_010278.1 hypothetical protein 2223384 5852039 APJL_2079 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653068.1 2222719 D 434271 CDS YP_001653069.1 165977476 5852137 2223491..2224297 1 NC_010278.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 2224297 map 5852137 map Actinobacillus pleuropneumoniae serovar 3 str. JL03 methionine aminopeptidase YP_001653069.1 2223491 D 434271 CDS YP_001653070.1 165977477 5852685 2224531..2225319 1 NC_010278.1 hypothetical protein 2225319 5852685 APJL_2081 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653070.1 2224531 D 434271 CDS YP_001653071.1 165977478 5852668 complement(2225462..2225956) 1 NC_010278.1 thiol-disulfide isomerase and thioredoxins 2225956 5852668 APJL_2082 Actinobacillus pleuropneumoniae serovar 3 str. JL03 thiol-disulfide isomerase and thioredoxins YP_001653071.1 2225462 R 434271 CDS YP_001653072.1 165977479 5852561 complement(2225989..2227008) 1 NC_010278.1 sucrose operon repressor 2227008 scrR 5852561 scrR Actinobacillus pleuropneumoniae serovar 3 str. JL03 sucrose operon repressor YP_001653072.1 2225989 R 434271 CDS YP_001653073.1 165977480 5852520 complement(2227079..2228515) 1 NC_010278.1 sucrose-6-phosphate hydrolase 2228515 scrB 5852520 scrB Actinobacillus pleuropneumoniae serovar 3 str. JL03 sucrose-6-phosphate hydrolase YP_001653073.1 2227079 R 434271 CDS YP_001653074.1 165977481 5852513 complement(2228567..2229490) 1 NC_010278.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 2229490 rbsK3 5852513 rbsK3 Actinobacillus pleuropneumoniae serovar 3 str. JL03 aminoimidazole riboside kinase YP_001653074.1 2228567 R 434271 CDS YP_001653075.1 165977482 5852504 2229634..2230713 1 NC_010278.1 copper-containing nitrite reductase 2230713 sufI2 5852504 sufI2 Actinobacillus pleuropneumoniae serovar 3 str. JL03 copper-containing nitrite reductase YP_001653075.1 2229634 D 434271 CDS YP_001653076.1 165977483 5852441 complement(2230781..2232031) 1 NC_010278.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 2232031 lolE 5852441 lolE Actinobacillus pleuropneumoniae serovar 3 str. JL03 outer membrane-specific lipoprotein transporter subunit LolE YP_001653076.1 2230781 R 434271 CDS YP_001653077.1 165977484 5852432 complement(2232031..2232744) 1 NC_010278.1 lipoprotein releasing system ATP-binding protein 2232744 lolD 5852432 lolD Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein releasing system ATP-binding protein YP_001653077.1 2232031 R 434271 CDS YP_001653078.1 165977485 5852426 complement(2232812..2233984) 1 NC_010278.1 lipoprotein releasing system transmembrane protein 2233984 lolC 5852426 lolC Actinobacillus pleuropneumoniae serovar 3 str. JL03 lipoprotein releasing system transmembrane protein YP_001653078.1 2232812 R 434271 CDS YP_001653079.1 165977486 5852415 complement(2234109..2235059) 1 NC_010278.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 2235059 5852415 APJL_2090 Actinobacillus pleuropneumoniae serovar 3 str. JL03 glycerate dehydrogenase YP_001653079.1 2234109 R 434271 CDS YP_001653080.1 165977487 5852371 complement(2235116..2235970) 1 NC_010278.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 2235970 kdsA 5852371 kdsA Actinobacillus pleuropneumoniae serovar 3 str. JL03 2-dehydro-3-deoxyphosphooctonate aldolase YP_001653080.1 2235116 R 434271 CDS YP_001653081.1 165977488 5852362 complement(2236021..2236887) 1 NC_010278.1 hypothetical protein 2236887 5852362 APJL_2092 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653081.1 2236021 R 434271 CDS YP_001653082.1 165977489 5852191 complement(2236871..2237833) 1 NC_010278.1 protein-glutamine N-methyl transferase 2237833 hemK 5852191 hemK Actinobacillus pleuropneumoniae serovar 3 str. JL03 protein-glutamine N-methyl transferase YP_001653082.1 2236871 R 434271 CDS YP_001653083.1 165977490 5852385 complement(2237763..2238290) 1 NC_010278.1 hypothetical protein 2238290 5852385 APJL_2094 Actinobacillus pleuropneumoniae serovar 3 str. JL03 hypothetical protein YP_001653083.1 2237763 R 434271 CDS YP_001653084.1 165977491 5852325 complement(2238353..2239354) 1 NC_010278.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2239354 prfA 5852325 prfA Actinobacillus pleuropneumoniae serovar 3 str. JL03 peptide chain release factor 1 YP_001653084.1 2238353 R 434271 CDS YP_001653085.1 165977492 5852497 complement(2239587..2240957) 1 NC_010278.1 rhodanese-related sulfur transferase 2240957 sseA 5852497 sseA Actinobacillus pleuropneumoniae serovar 3 str. JL03 rhodanese-related sulfur transferase YP_001653085.1 2239587 R 434271 CDS YP_001653086.1 165977493 5852549 complement(2240966..2241958) 1 NC_010278.1 putative inner membrane protein 2241958 5852549 APJL_2097 Actinobacillus pleuropneumoniae serovar 3 str. JL03 putative inner membrane protein YP_001653086.1 2240966 R 434271 CDS