-- dump date 20140618_191039 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 434271000001 SEQ_END SEQ_END NC_010278.1 2242062 2242062 DR NC_010278.1; contig end 2242062..2242062 Actinobacillus pleuropneumoniae serovar 3 str. JL03 YP_001651051.1 CDS dnaA NC_010278.1 2 1486 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 2..1486 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851472 YP_001651052.1 CDS dnaN NC_010278.1 1503 2606 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1503..2606 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850820 YP_001651053.1 CDS recF NC_010278.1 2666 3748 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2666..3748 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851494 YP_001651054.1 CDS sodC NC_010278.1 3804 4376 R superoxide dismutase Cu-Zn complement(3804..4376) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851514 YP_001651055.1 CDS asd NC_010278.1 4559 5671 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4559..5671 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851493 YP_001651056.1 CDS ompP2A1 NC_010278.1 5798 6088 R outer membrane protein P2 complement(5798..6088) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851634 YP_001651057.1 CDS ompP2A2 NC_010278.1 6113 6928 R outer membrane protein P2 complement(6113..6928) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851704 YP_001651058.1 CDS lpxB NC_010278.1 7077 8258 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 7077..8258 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850778 YP_001651059.1 CDS sohB NC_010278.1 8288 9343 D SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 8288..9343 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851482 YP_001651060.1 CDS mraZ NC_010278.1 9578 10036 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 9578..10036 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851524 YP_001651061.1 CDS mraW NC_010278.1 10062 11003 D S-adenosyl-methyltransferase MraW 10062..11003 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851430 YP_001651062.1 CDS ftsL NC_010278.1 11016 11330 D cell division protein 11016..11330 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851006 YP_001651063.1 CDS ftsI NC_010278.1 11334 13394 D penicillin-binding protein 3 11334..13394 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851557 YP_001651064.1 CDS murE NC_010278.1 13418 14920 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 13418..14920 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851590 YP_001651065.1 CDS murF NC_010278.1 15135 16529 D UDP-MurNAc-pentapeptide synthetase 15135..16529 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851589 YP_001651066.1 CDS mraY NC_010278.1 16634 17716 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 16634..17716 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851572 YP_001651067.1 CDS murD NC_010278.1 17800 19110 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 17800..19110 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851577 YP_001651068.1 CDS ftsW NC_010278.1 19112 20290 D cell division protein 19112..20290 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851523 YP_001651069.1 CDS murG NC_010278.1 20445 21500 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 20445..21500 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851601 YP_001651070.1 CDS murC NC_010278.1 21552 22979 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 21552..22979 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851348 YP_001651071.1 CDS ddl NC_010278.1 23087 23998 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 23087..23998 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851576 YP_001651072.1 CDS ftsQ NC_010278.1 24103 24792 D cell division protein 24103..24792 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851022 YP_001651073.1 CDS ftsA NC_010278.1 24818 26092 D cell division protein 24818..26092 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851222 YP_001651074.1 CDS ftsZ NC_010278.1 26131 27309 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 26131..27309 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850794 YP_001651075.1 CDS lpxC NC_010278.1 27377 28297 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 27377..28297 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850984 YP_001651076.1 CDS recN NC_010278.1 28384 30132 D DNA repair protein 28384..30132 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851667 YP_001651077.1 CDS APJL_0027 NC_010278.1 30274 31677 R peptide transport system ATP-binding protein complement(30274..31677) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851339 YP_001651078.1 CDS APJL_0028 NC_010278.1 31677 32462 R nickel transport system permease complement(31677..32462) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851503 YP_001651079.1 CDS gsiC NC_010278.1 32465 33412 R glutathione permease complement(32465..33412) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851005 YP_001651080.1 CDS APJL_0030 NC_010278.1 33506 35080 R dipeptide ABC transporter periplasmic protein complement(33506..35080) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850825 YP_001651081.1 CDS prfC NC_010278.1 35274 36854 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(35274..36854) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851529 YP_001651082.1 CDS APJL_0032 NC_010278.1 37037 37504 D membrane protein 37037..37504 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851499 YP_001651083.1 CDS APJL_0033 NC_010278.1 37551 38066 D membrane protein 37551..38066 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850845 YP_001651084.1 CDS pth NC_010278.1 38193 38777 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 38193..38777 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851033 YP_001651085.1 CDS engD NC_010278.1 38886 39977 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 38886..39977 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851988 YP_001651086.1 CDS APJL_0036 NC_010278.1 40049 40486 D putative protein-S-isoprenylcysteine methyltransferase 40049..40486 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851124 YP_001651087.1 CDS APJL_0037 NC_010278.1 40536 40811 R hypothetical protein complement(40536..40811) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851127 YP_001651088.1 CDS lpp NC_010278.1 40842 41306 R outer membrane lipoprotein complement(40842..41306) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851571 YP_001651089.1 CDS APJL_0039 NC_010278.1 41333 41929 R hypothetical protein complement(41333..41929) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851976 YP_001651090.1 CDS argS NC_010278.1 42108 43754 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 42108..43754 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852077 YP_001651091.1 CDS obgE NC_010278.1 43898 45073 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 43898..45073 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852064 YP_001651092.1 CDS APJL_0042 NC_010278.1 45148 45759 D hypothetical protein 45148..45759 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852062 YP_001651093.1 CDS APJL_0043 NC_010278.1 45859 46602 R Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase complement(45859..46602) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852116 YP_001651094.1 CDS pssA NC_010278.1 46681 48045 R catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase complement(46681..48045) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852085 YP_001651095.1 CDS ileS NC_010278.1 48197 50965 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(48197..50965) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852093 YP_001651096.1 CDS ribF NC_010278.1 51074 52036 R riboflavin biosynthesis protein complement(51074..52036) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852096 YP_001651097.1 CDS nadR NC_010278.1 52369 53649 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 52369..53649 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852791 YP_001651098.1 CDS APJL_0048 NC_010278.1 53646 54344 D diadenosine tetraphosphatase and related serine/threonine protein phosphatase 53646..54344 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852794 YP_001651099.1 CDS arcA NC_010278.1 54517 55233 D two-component response regulator 54517..55233 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852795 YP_001651100.1 CDS APJL_0050 NC_010278.1 55285 55803 D hypothetical protein 55285..55803 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852253 YP_001651101.1 CDS APJL_0051 NC_010278.1 55886 56422 R 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase complement(55886..56422) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851020 YP_001651102.1 CDS APJL_0052 NC_010278.1 56477 57172 D hypothetical protein 56477..57172 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852358 YP_001651103.1 CDS typA NC_010278.1 57319 59211 D GTP-binding protein 57319..59211 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852477 YP_001651104.1 CDS grxA NC_010278.1 59370 59633 D functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 59370..59633 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852569 YP_001651105.1 CDS rph NC_010278.1 59699 60415 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(59699..60415) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852672 YP_001651106.1 CDS APJL_0056 NC_010278.1 60619 61482 D hypothetical protein 60619..61482 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852652 YP_001651107.1 CDS APJL_0057 NC_010278.1 61491 62378 D hypothetical protein 61491..62378 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852155 YP_001651108.1 CDS fdx1 NC_010278.1 62428 62688 R ferredoxin-like protein complement(62428..62688) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852121 YP_001651109.1 CDS narP NC_010278.1 62834 63463 R nitrate/nitrite response regulator protein complement(62834..63463) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852812 YP_001651110.1 CDS rlmL NC_010278.1 63667 65805 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 63667..65805 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852800 YP_001651111.1 CDS APJL_0061 NC_010278.1 65863 66342 D tRNA/rRNA methyltransferase 65863..66342 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852792 YP_001651112.1 CDS mipB NC_010278.1 66482 67429 R transaldolase B complement(66482..67429) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851678 YP_001651113.1 CDS dppA1 NC_010278.1 73587 75182 D dipeptide transport protein 73587..75182 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851579 YP_001651114.1 CDS dppA2 NC_010278.1 75349 76950 D dipeptide transport protein 75349..76950 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851591 YP_001651115.1 CDS dppB NC_010278.1 77076 78080 D dipeptide transport system permease 77076..78080 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851593 YP_001651116.1 CDS dppC NC_010278.1 78158 79048 D dipeptide transport system permease 78158..79048 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851598 YP_001651117.1 CDS dppD NC_010278.1 79059 80045 D DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 79059..80045 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852854 YP_001651118.1 CDS dppF NC_010278.1 80058 81047 D Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 80058..81047 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852796 YP_001651119.1 CDS psiE1 NC_010278.1 81120 81530 R phosphate-starvation-inducible protein PsiE complement(81120..81530) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852789 YP_001651120.1 CDS APJL_0070 NC_010278.1 81608 82240 R hypothetical protein complement(81608..82240) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852806 YP_001651121.1 CDS APJL_0071 NC_010278.1 82295 82639 R hypothetical protein complement(82295..82639) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852807 YP_001651122.1 CDS ilvE NC_010278.1 82726 83763 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(82726..83763) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852786 YP_001651123.1 CDS APJL_0073 NC_010278.1 83906 84238 R glutaredoxin-like protein complement(83906..84238) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852394 YP_001651124.1 CDS recR NC_010278.1 84310 84975 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(84310..84975) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852506 YP_001651125.1 CDS APJL_0075 NC_010278.1 84986 85315 R hypothetical protein complement(84986..85315) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851686 YP_001651126.1 CDS tonB2 NC_010278.1 85484 86218 R TobB energy transducing protein complement(85484..86218) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852741 YP_001651127.1 CDS exbD2 NC_010278.1 86351 86740 R biopolymer transport protein complement(86351..86740) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852777 YP_001651128.1 CDS exbB2 NC_010278.1 86785 87228 R biopolymer transport protein complement(86785..87228) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852100 YP_001651129.1 CDS pspE NC_010278.1 87425 87751 D rhodanese-related sulfur transferase 87425..87751 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852083 YP_001651130.1 CDS APJL_0080 NC_010278.1 87795 88640 D thioredoxin-like protein 87795..88640 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852040 YP_001651131.1 CDS dhaM NC_010278.1 88714 89121 R PTS system mannnose-specific transporter subunit IIA complement(88714..89121) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852047 YP_001651132.1 CDS dAK1 NC_010278.1 89130 89756 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(89130..89756) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852009 YP_001651133.1 CDS dhaK NC_010278.1 89758 90828 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(89758..90828) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851692 YP_001651134.1 CDS trxB NC_010278.1 90998 91951 D thioredoxin reductase 90998..91951 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852819 YP_001651135.1 CDS kdsB NC_010278.1 92059 92811 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 92059..92811 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852820 YP_001651136.1 CDS APJL_0086 NC_010278.1 92935 93360 D hypothetical protein 92935..93360 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851979 YP_001651137.1 CDS nudC NC_010278.1 93433 94203 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(93433..94203) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851963 YP_001651138.1 CDS rluB NC_010278.1 94221 94916 R pseudouridylate synthase complement(94221..94916) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851574 YP_001651139.1 CDS APJL_0089 NC_010278.1 94920 95738 R hypothetical protein complement(94920..95738) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851521 YP_001651140.1 CDS APJL_0090 NC_010278.1 95768 96232 R hypothetical protein complement(95768..96232) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851491 YP_001651141.1 CDS APJL_0091 NC_010278.1 96255 97637 R catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase complement(96255..97637) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850967 YP_001651142.1 CDS sirA NC_010278.1 97673 97849 D SirA protein 97673..97849 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850900 YP_001651143.1 CDS APJL_0093 NC_010278.1 97899 98339 R hypothetical protein complement(97899..98339) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851541 YP_001651144.1 CDS engB NC_010278.1 98341 98961 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(98341..98961) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851440 YP_001651145.1 CDS APJL_0095 NC_010278.1 99243 99659 R hypothetical protein complement(99243..99659) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851412 YP_001651146.1 CDS gufA NC_010278.1 99697 100527 R GufA-like protein complement(99697..100527) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851219 YP_001651147.1 CDS ilvD NC_010278.1 100678 102513 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(100678..102513) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850902 YP_001651148.1 CDS ilvM NC_010278.1 102631 102849 R acetolactate synthase 2 regulatory subunit complement(102631..102849) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851474 YP_001651149.1 CDS ilvG NC_010278.1 102867 104519 R acetohydroxy acid synthase II large subunit complement(102867..104519) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851476 YP_001651150.1 CDS nrfA NC_010278.1 104918 106426 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 104918..106426 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851487 YP_001651151.1 CDS nrfB NC_010278.1 106447 107094 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 106447..107094 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851706 YP_001651152.1 CDS nrfC NC_010278.1 107094 107771 D nitrate reductase, Fe-S protein 107094..107771 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851705 YP_001651153.1 CDS nrfD NC_010278.1 107771 108739 D nitrate reductase, transmembrane protein 107771..108739 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851356 YP_001651154.1 CDS uraA NC_010278.1 121391 122620 R uracil permease complement(121391..122620) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851690 YP_001651155.1 CDS putA NC_010278.1 122779 126384 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(122779..126384) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851486 YP_001651156.1 CDS putP NC_010278.1 126487 128001 R sodium/proline symporter, proline permease complement(126487..128001) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851507 YP_001651157.1 CDS APJL_0109 NC_010278.1 128576 129361 R putative HTH-type transcriptional regulator complement(128576..129361) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851409 YP_001651158.1 CDS APJL_0110 NC_010278.1 129358 129933 R hypothetical protein complement(129358..129933) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851527 YP_001651159.1 CDS APJL_0111 NC_010278.1 130204 130524 R hypothetical protein complement(130204..130524) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851446 YP_001651160.1 CDS APJL_0112 NC_010278.1 130602 131153 D hypothetical protein 130602..131153 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851135 YP_001651161.1 CDS hemE NC_010278.1 131259 132323 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 131259..132323 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851531 YP_001651162.1 CDS APJL_0114 NC_010278.1 132437 133027 D hypothetical protein 132437..133027 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851422 YP_001651163.1 CDS hupA NC_010278.1 133163 133435 D DNA-binding protein HU 133163..133435 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850919 YP_001651164.1 CDS thyA NC_010278.1 133488 134339 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(133488..134339) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851429 YP_001651165.1 CDS APJL_0117 NC_010278.1 134427 135011 D hypothetical protein 134427..135011 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851431 YP_001651166.1 CDS bioB NC_010278.1 135107 136117 D biotin synthetase 135107..136117 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851552 YP_001651167.1 CDS cspC NC_010278.1 136181 136390 R cold shock-like protein complement(136181..136390) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850713 YP_001651168.1 CDS proQ NC_010278.1 136753 137301 D affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 136753..137301 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851085 YP_001651169.1 CDS prc NC_010278.1 137393 139405 D Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 137393..139405 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850978 YP_001651170.1 CDS APJL_0122 NC_010278.1 139502 141067 D hypothetical protein 139502..141067 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851223 YP_001651171.1 CDS APJL_0123 NC_010278.1 141239 141793 D hypothetical protein 141239..141793 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851528 YP_001651172.1 CDS APJL_0124 NC_010278.1 141811 142440 D glyoxalase II family protein 141811..142440 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850722 YP_001651173.1 CDS APJL_0125 NC_010278.1 142443 143192 R hypothetical protein complement(142443..143192) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850843 YP_001651174.1 CDS APJL_0126 NC_010278.1 143189 143563 R lipoprotein complement(143189..143563) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851018 YP_001651175.1 CDS APJL_0127 NC_010278.1 143565 143930 R HIT-like protein complement(143565..143930) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850960 YP_001651176.1 CDS yfeD NC_010278.1 144002 144832 R iron (chelated) transport system membrane protein complement(144002..144832) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851239 YP_001651177.1 CDS yfeC NC_010278.1 144825 145679 R iron (chelated) transport system membrane protein complement(144825..145679) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850760 YP_001651178.1 CDS rnhB NC_010278.1 145680 146273 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(145680..146273) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850839 YP_001651179.1 CDS APJL_0131 NC_010278.1 146296 147330 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(146296..147330) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851262 YP_001651180.1 CDS gcvA NC_010278.1 147840 148730 D Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 147840..148730 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851484 YP_001651181.1 CDS APJL_0133 NC_010278.1 148730 149410 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 148730..149410 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851501 YP_001651182.1 CDS cysB NC_010278.1 149410 150393 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 149410..150393 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851198 YP_001651183.1 CDS APJL_0135 NC_010278.1 150394 151038 D hypothetical protein 150394..151038 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851500 YP_001651184.1 CDS ansB NC_010278.1 151117 152166 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(151117..152166) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851289 YP_001651185.1 CDS pyrG NC_010278.1 152470 154107 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 152470..154107 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851526 YP_001651186.1 CDS APJL_0138 NC_010278.1 154207 154713 D hypothetical protein 154207..154713 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851362 YP_001651187.1 CDS leuD NC_010278.1 154759 155361 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(154759..155361) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851361 YP_001651188.1 CDS leuC NC_010278.1 155372 156781 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(155372..156781) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850717 YP_001651189.1 CDS APJL_0141 NC_010278.1 157123 158238 D hypothetical protein 157123..158238 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850959 YP_001651190.1 CDS APJL_0142 NC_010278.1 158366 159628 D hypothetical protein 158366..159628 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851437 YP_001651191.1 CDS grk NC_010278.1 159639 160772 D glycerate kinase 159639..160772 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851522 YP_001651192.1 CDS APJL_0144 NC_010278.1 160791 161063 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 160791..161063 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851388 YP_001651193.1 CDS APJL_0145 NC_010278.1 161134 162693 R ATP-dependent endonuclease complement(161134..162693) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851351 YP_001651194.1 CDS APJL_0146 NC_010278.1 162697 164076 R Rossmann fold nucleotide-binding protein complement(162697..164076) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851360 YP_001651195.1 CDS APJL_0147 NC_010278.1 164136 165113 R tRNA-dihydrouridine synthase A complement(164136..165113) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851666 YP_001651196.1 CDS nrdB_1 NC_010278.1 165466 166443 D ribonucleoside-diphosphate reductase subunit beta 1 165466..166443 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851397 YP_001651197.1 CDS nrdA_1 NC_010278.1 166430 168094 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 166430..168094 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851427 YP_001651198.1 CDS orfG NC_010278.1 168229 168828 R cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein complement(168229..168828) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851573 YP_001651199.1 CDS nqrA NC_010278.1 169283 170632 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 169283..170632 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851670 YP_001651200.1 CDS nqrB NC_010278.1 170637 171869 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 170637..171869 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851582 YP_001651201.1 CDS nqrC NC_010278.1 171872 172645 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 171872..172645 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851581 YP_001651202.1 CDS nqrD NC_010278.1 172645 173268 D Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 172645..173268 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851578 YP_001651203.1 CDS nqrE NC_010278.1 173270 173866 D Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 173270..173866 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851584 YP_001651204.1 CDS nqrF NC_010278.1 173877 175106 D uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 173877..175106 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851587 YP_001651205.1 CDS apbE NC_010278.1 175313 176344 D thiamine biosynthesis lipoprotein 175313..176344 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851592 YP_001651206.1 CDS APJL_0158 NC_010278.1 176357 176602 D hypothetical protein 176357..176602 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851596 YP_001651207.1 CDS mnmA NC_010278.1 176831 178000 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 176831..178000 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851701 YP_001651208.1 CDS hcaT NC_010278.1 178073 179227 R putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter complement(178073..179227) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851597 YP_001651209.1 CDS APJL_0161 NC_010278.1 179224 180054 R pyrroline-5-carboxylate reductase complement(179224..180054) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851317 YP_001651210.1 CDS rdgC NC_010278.1 180216 181124 D Required for efficient pilin antigenic variation; recombination associated protein 180216..181124 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851595 YP_001651211.1 CDS APJL_0163 NC_010278.1 181134 181739 D phosphatase/phosphohexomutase 181134..181739 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851594 YP_001651212.1 CDS APJL_0164 NC_010278.1 181994 183775 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(181994..183775) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851588 YP_001651213.1 CDS APJL_0165 NC_010278.1 183780 184247 R organic radical activating protein complement(183780..184247) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851586 YP_001651214.1 CDS rnfA NC_010278.1 184629 185210 D Na(+)-translocating NADH-quinone reductase subunit E 184629..185210 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851583 YP_001651215.1 CDS rnfB NC_010278.1 185210 185821 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 185210..185821 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851575 YP_001651216.1 CDS rnfC NC_010278.1 185814 188126 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 185814..188126 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850711 YP_001651217.1 CDS APJL_0169 NC_010278.1 188119 188763 D membrane protein 188119..188763 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851357 YP_001651218.1 CDS rnfD NC_010278.1 188783 189829 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 188783..189829 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851496 YP_001651219.1 CDS rnfG NC_010278.1 189829 190461 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 189829..190461 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851428 YP_001651220.1 CDS rnfE NC_010278.1 190473 191159 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 190473..191159 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851290 YP_001651221.1 CDS lpxM NC_010278.1 191168 192124 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 191168..192124 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851101 YP_001651222.1 CDS APJL_0174 NC_010278.1 192184 193170 R hypothetical protein complement(192184..193170) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851199 YP_001651223.1 CDS tbpA NC_010278.1 193612 194577 D thiamine-binding periplasmic protein 193612..194577 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851063 YP_001651224.1 CDS dksA NC_010278.1 194784 195233 D dosage-dependent DnaK suppressor protein 194784..195233 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851169 YP_001651225.1 CDS pcnB NC_010278.1 195376 196908 D polyA polymerase 195376..196908 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850833 YP_001651226.1 CDS folK NC_010278.1 196978 197448 D 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 196978..197448 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850809 YP_001651227.1 CDS APJL_0179 NC_010278.1 197483 197704 R hypothetical protein complement(197483..197704) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850926 YP_001651228.1 CDS APJL_0180 NC_010278.1 197701 200430 R hypothetical protein complement(197701..200430) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851570 YP_001651229.1 CDS APJL_0181 NC_010278.1 200430 200951 R hypothetical protein complement(200430..200951) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850904 YP_001651230.1 CDS gloA1 NC_010278.1 201352 201759 D lactoylglutathione lyase 201352..201759 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851321 YP_001651231.1 CDS rnt NC_010278.1 201899 202555 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 201899..202555 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851064 YP_001651232.1 CDS APJL_0184 NC_010278.1 202648 203925 R manganese transporter NRAMP complement(202648..203925) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851282 YP_001651233.1 CDS tyrA NC_010278.1 204501 205622 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(204501..205622) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851308 YP_001651234.1 CDS aroF NC_010278.1 205735 206796 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(205735..206796) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851370 YP_001651235.1 CDS APJL_0187 NC_010278.1 206838 207884 R putative glycosyltransferase complement(206838..207884) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851342 YP_001651236.1 CDS pykA NC_010278.1 207972 209312 R pyruvate kinase II complement(207972..209312) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851492 YP_001651237.1 CDS sixA NC_010278.1 209543 210034 D phosphohistidine phosphatase 209543..210034 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850817 YP_001651238.1 CDS APJL_0190 NC_010278.1 210257 211219 D putative dehydrogenase 210257..211219 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850964 YP_001651239.1 CDS fis NC_010278.1 211247 211543 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 211247..211543 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851327 YP_001651240.1 CDS APJL_0192 NC_010278.1 211608 212966 R putative sodium-dependent transporter complement(211608..212966) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850971 YP_001651241.1 CDS dam NC_010278.1 213031 213864 R DNA adenine methylase complement(213031..213864) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851975 YP_001651242.1 CDS aroB NC_010278.1 213857 214846 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(213857..214846) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851727 YP_001651243.1 CDS aroK NC_010278.1 215031 215552 R catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(215031..215552) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851274 YP_001651244.1 CDS mrcA NC_010278.1 215814 218381 R penicillin-binding protein 1A complement(215814..218381) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851024 YP_001651245.1 CDS APJL_0197 NC_010278.1 218520 219200 D Tfp pilus assembly protein 218520..219200 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851768 YP_001651246.1 CDS APJL_0198 NC_010278.1 219182 219703 D hypothetical protein 219182..219703 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850996 YP_001651247.1 CDS APJL_0199 NC_010278.1 219706 220233 D hypothetical protein 219706..220233 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850747 YP_001651248.1 CDS APJL_0200 NC_010278.1 220226 220630 D hypothetical protein 220226..220630 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851405 YP_001651249.1 CDS hofQ NC_010278.1 220642 221940 D type II secretory protein 220642..221940 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851218 YP_001651250.1 CDS nusB NC_010278.1 222066 222479 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 222066..222479 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851032 YP_001651251.1 CDS thiL NC_010278.1 222547 223509 D thiamin-monophosphate kinase 222547..223509 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850768 YP_001651252.1 CDS pgpA NC_010278.1 223522 223995 D phosphatidylglycerophosphatase A 223522..223995 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850982 YP_001651253.1 CDS rhtB NC_010278.1 224011 224634 D threonine efflux protein 224011..224634 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851642 YP_001651254.1 CDS APJL_0206 NC_010278.1 224682 225719 R putative tRNA/rRNA methyltransferase complement(224682..225719) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851334 YP_001651255.1 CDS suhB NC_010278.1 225894 226697 D inositol-1-monophosphatase 225894..226697 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851164 YP_001651256.1 CDS dxs NC_010278.1 226818 228671 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 226818..228671 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850977 YP_001651257.1 CDS APJL_0209 NC_010278.1 228717 229535 R transposase complement(228717..229535) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851771 YP_001651258.1 CDS APJL_0210 NC_010278.1 229541 229891 R transposase and inactivated derivative complement(229541..229891) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850987 YP_001651259.1 CDS APJL_0211 NC_010278.1 229898 230053 R transposase and inactivated derivative complement(229898..230053) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850863 YP_001651260.1 CDS glyA NC_010278.1 230143 231408 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(230143..231408) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851434 YP_001651261.1 CDS ppnK NC_010278.1 231639 232526 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(231639..232526) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851413 YP_001651262.1 CDS APJL_0214 NC_010278.1 232617 235964 R helicase complement(232617..235964) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850857 YP_001651263.1 CDS cas1 NC_010278.1 235961 236917 R CRISPR-associated protein complement(235961..236917) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851055 YP_001651264.1 CDS APJL_0216 NC_010278.1 239167 239736 R hypothetical protein complement(239167..239736) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851545 YP_001651265.1 CDS APJL_0217 NC_010278.1 239739 240734 R CRISPR-associated protein complement(239739..240734) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850754 YP_001651266.1 CDS APJL_0218 NC_010278.1 240736 241695 R CRISPR-associated protein complement(240736..241695) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851267 YP_001651267.1 CDS APJL_0219 NC_010278.1 241692 243041 R CRISPR-associated protein complement(241692..243041) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851653 YP_001651268.1 CDS thrS NC_010278.1 243489 245420 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 243489..245420 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851158 YP_001651269.1 CDS APJL_0221 NC_010278.1 245562 246236 D putative lipoprotein 245562..246236 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850994 YP_001651270.1 CDS APJL_0222 NC_010278.1 246267 246593 D hypothetical protein 246267..246593 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851550 YP_001651271.1 CDS APJL_0223 NC_010278.1 246605 247264 D hypothetical protein 246605..247264 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851554 YP_001651272.1 CDS infC NC_010278.1 247542 248021 D translation initiation factor IF-3 247542..248021 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851390 YP_001651273.1 CDS rpmI NC_010278.1 248270 248467 D 50S ribosomal protein L35 248270..248467 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851404 YP_001651274.1 CDS rplT NC_010278.1 248535 248888 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 248535..248888 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851324 YP_001651275.1 CDS APJL_0227 NC_010278.1 248937 249473 D hypothetical protein 248937..249473 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851000 YP_001651276.1 CDS APJL_0228 NC_010278.1 249506 249799 D hypothetical protein 249506..249799 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851742 YP_001651277.1 CDS APJL_0229 NC_010278.1 249878 250387 D transposase and inactivated derivative 249878..250387 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851714 YP_001651278.1 CDS APJL_0230 NC_010278.1 250393 250716 D putative transposase-like protein 250393..250716 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851058 YP_001651279.1 CDS APJL_0231 NC_010278.1 250740 250880 D transposase 250740..250880 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851485 YP_001651280.1 CDS APJL_0232 NC_010278.1 250896 251087 D transposase 250896..251087 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850752 YP_001651281.1 CDS APJL_0233 NC_010278.1 251135 252430 R hypothetical protein complement(251135..252430) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851247 YP_001651282.1 CDS rluA NC_010278.1 252474 253124 R RNA pseudouridine synthase complement(252474..253124) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851187 YP_001651283.1 CDS gpmB NC_010278.1 253174 253806 D phosphoglycerate mutase 253174..253806 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851269 YP_001651284.1 CDS APJL_0236 NC_010278.1 253873 254286 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(253873..254286) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851813 YP_001651285.1 CDS APJL_0237 NC_010278.1 254339 254899 R hypothetical protein complement(254339..254899) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851129 YP_001651286.1 CDS APJL_0238 NC_010278.1 254899 255630 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(254899..255630) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851733 YP_001651287.1 CDS APJL_0239 NC_010278.1 255806 256396 R putative lipoprotein complement(255806..256396) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851323 YP_001651288.1 CDS bolA NC_010278.1 256525 256836 D putative transcriptional regulator 256525..256836 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851471 YP_001651289.1 CDS APJL_0241 NC_010278.1 257229 257603 R putative lipoprotein complement(257229..257603) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851401 YP_001651290.1 CDS APJL_0242 NC_010278.1 257623 257931 R hypothetical protein complement(257623..257931) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851134 YP_001651291.1 CDS APJL_0243 NC_010278.1 258034 258360 D hypothetical protein 258034..258360 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851402 YP_001651292.1 CDS secA NC_010278.1 258469 261186 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 258469..261186 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851188 YP_001651293.1 CDS APJL_0245 NC_010278.1 261316 262503 D FOG: TPR repeat; hypothetical protein 261316..262503 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851655 YP_001651294.1 CDS mutT1 NC_010278.1 262500 262898 D mutator MutT protein 262500..262898 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851646 YP_001651295.1 CDS argC NC_010278.1 263133 264086 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 263133..264086 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851457 YP_001651296.1 CDS argB NC_010278.1 264107 264961 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 264107..264961 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851082 YP_001651297.1 CDS argD2 NC_010278.1 264975 266156 D catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 264975..266156 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851417 YP_001651298.1 CDS tbpB2 NC_010278.1 266370 268079 D transferrin-binding protein 2 266370..268079 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850995 YP_001651299.1 CDS rho NC_010278.1 270930 272192 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(270930..272192) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851649 YP_001651300.1 CDS cysK NC_010278.1 272390 273340 R cysteine synthase complement(272390..273340) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851389 YP_001651301.1 CDS thrB NC_010278.1 273552 274502 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(273552..274502) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851295 YP_001651302.1 CDS sodA NC_010278.1 277366 278007 D manganese superoxide dismutase 277366..278007 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851780 YP_001651303.1 CDS alr NC_010278.1 278095 279219 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(278095..279219) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851213 YP_001651304.1 CDS recD NC_010278.1 279340 281259 D exodeoxyribonuclease V subunit alpha 279340..281259 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851002 YP_001651305.1 CDS pepD NC_010278.1 287144 288721 R aminoacyl-histidine dipeptidase complement(287144..288721) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851761 YP_001651306.1 CDS gpt NC_010278.1 288771 289244 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 288771..289244 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851722 YP_001651307.1 CDS gmk NC_010278.1 289328 289948 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 289328..289948 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851236 YP_001651308.1 CDS APJL_0265 NC_010278.1 290050 291444 D outer membrane protein 290050..291444 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852025 YP_001651309.1 CDS APJL_0266 NC_010278.1 291492 291788 R hypothetical protein complement(291492..291788) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851836 YP_001651310.1 CDS APJL_0267 NC_010278.1 291781 292215 R hypothetical protein complement(291781..292215) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851999 YP_001651311.1 CDS modC NC_010278.1 292263 293318 R Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein complement(292263..293318) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852004 YP_001651312.1 CDS modB NC_010278.1 293322 294011 R part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease complement(293322..294011) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851763 YP_001651313.1 CDS modA NC_010278.1 294071 294829 R molybdate-binding periplasmic protein, ABC transporter complement(294071..294829) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851204 YP_001651314.1 CDS APJL_0271 NC_010278.1 294925 295686 R ABC transporter permease complement(294925..295686) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851153 YP_001651315.1 CDS APJL_0272 NC_010278.1 295690 296598 R ABC transporter ATP-binding protein complement(295690..296598) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851073 YP_001651316.1 CDS dnaX NC_010278.1 296598 298664 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(296598..298664) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851315 YP_001651317.1 CDS apt NC_010278.1 298713 299261 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(298713..299261) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851490 YP_001651318.1 CDS APJL_0275 NC_010278.1 299462 300094 D two-component response regulator involved in C4-dicarboxylate transport 299462..300094 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851498 YP_001651319.1 CDS APJL_0278 NC_010278.1 300467 301561 D threonine synthase 300467..301561 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851605 YP_001651320.1 CDS APJL_0279 NC_010278.1 301576 302067 D hypothetical protein 301576..302067 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851168 YP_001651321.1 CDS yfeB NC_010278.1 302178 302933 R iron (chelated) transporter, ATP-binding protein complement(302178..302933) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851399 YP_001651322.1 CDS APJL_0283 NC_010278.1 303899 304252 R putative sulfite reductase complement(303899..304252) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851313 YP_001651323.1 CDS APJL_0284 NC_010278.1 304286 304951 R transporter complement(304286..304951) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851319 YP_001651324.1 CDS pgsA NC_010278.1 305133 305684 D CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 305133..305684 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850756 YP_001651325.1 CDS frpB NC_010278.1 305804 307774 D iron-regulated outer membrane protein 305804..307774 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851335 YP_001651326.1 CDS uvrC NC_010278.1 307927 309759 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 307927..309759 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851131 YP_001651327.1 CDS APJL_0288 NC_010278.1 309828 310580 D TatD family deoxyribonuclease 309828..310580 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851447 YP_001651328.1 CDS rep NC_010278.1 310717 312735 R ATP-dependent DNA helicase complement(310717..312735) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851406 YP_001651329.1 CDS potA NC_010278.1 313069 314184 D functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 313069..314184 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851453 YP_001651330.1 CDS potB NC_010278.1 314171 315037 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 314171..315037 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851480 YP_001651331.1 CDS potC NC_010278.1 315037 315804 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 315037..315804 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850916 YP_001651332.1 CDS ruvB NC_010278.1 316686 317570 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 316686..317570 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851520 YP_001651333.1 CDS ubiG NC_010278.1 317627 318364 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(317627..318364) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851196 YP_001651334.1 CDS gyrA NC_010278.1 318511 321201 D DNA gyrase subunit A 318511..321201 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851566 YP_001651335.1 CDS hsdM2 NC_010278.1 321238 322851 D putative type I restriction-modification systemmethyltransferase subunit 321238..322851 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850991 YP_001651336.1 CDS APJL_0299 NC_010278.1 322848 323849 D hypothetical protein 322848..323849 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850938 YP_001651337.1 CDS APJL_0300 NC_010278.1 324067 324363 D hypothetical protein 324067..324363 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851383 YP_001651338.1 CDS APJL_0301 NC_010278.1 324400 324978 D hypothetical protein 324400..324978 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850811 YP_001651339.1 CDS APJL_0302 NC_010278.1 325144 326313 D putative type I restriction enzyme specificity protein 325144..326313 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851774 YP_001651340.1 CDS APJL_0303 NC_010278.1 326325 327440 D anticodon nuclease 326325..327440 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851181 YP_001651341.1 CDS hsdR NC_010278.1 327447 330584 D type I site-specific deoxyribonuclease 327447..330584 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851512 YP_001651342.1 CDS uup NC_010278.1 330603 332546 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 330603..332546 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851311 YP_001651343.1 CDS APJL_0306 NC_010278.1 332546 333310 D hypothetical protein 332546..333310 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851602 YP_001651344.1 CDS APJL_0307 NC_010278.1 333389 333721 R hypothetical protein complement(333389..333721) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851285 YP_001651345.1 CDS cydA NC_010278.1 334178 335728 D cytochrome D ubiquinol oxidase, subunit I 334178..335728 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851421 YP_001651346.1 CDS cydB NC_010278.1 335742 336878 D cytochrome D ubiquinol oxidase subunit II 335742..336878 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851420 YP_001651347.1 CDS APJL_0310 NC_010278.1 336891 336989 D hypothetical protein 336891..336989 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851061 YP_001651348.1 CDS APJL_0311 NC_010278.1 337001 337303 D hypothetical protein 337001..337303 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851280 YP_001651349.1 CDS APJL_0312 NC_010278.1 337446 337835 D hypothetical protein 337446..337835 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850739 YP_001651350.1 CDS tolQ NC_010278.1 337870 338550 D colicin transport protein 337870..338550 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850801 YP_001651351.1 CDS tolR NC_010278.1 338629 339069 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 338629..339069 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851318 YP_001651352.1 CDS tolA1 NC_010278.1 339085 340356 D colicin import membrane protein 339085..340356 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850905 YP_001651353.1 CDS tolB NC_010278.1 340374 341654 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 340374..341654 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851364 YP_001651354.1 CDS pal NC_010278.1 341681 342139 D peptidoglycan-associated outer membrane lipoprotein 341681..342139 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850944 YP_001651355.1 CDS APJL_0318 NC_010278.1 342269 343123 D putative permease 342269..343123 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851509 YP_001651356.1 CDS djlA NC_010278.1 343203 344063 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 343203..344063 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851340 YP_001651357.1 CDS APJL_0320 NC_010278.1 344148 345110 D putative nitrogen regulator protein 344148..345110 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851263 YP_001651358.1 CDS APJL_0321 NC_010278.1 345162 346208 D hypothetical protein 345162..346208 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851734 YP_001651359.1 CDS APJL_0322 NC_010278.1 346396 348312 R ABC transporter ATP-binding protein complement(346396..348312) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851359 YP_001651360.1 CDS APJL_0323 NC_010278.1 348473 348715 D hypothetical protein 348473..348715 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851104 YP_001651361.1 CDS moeB NC_010278.1 350149 350895 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 350149..350895 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850974 YP_001651362.1 CDS rumA NC_010278.1 351292 352620 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(351292..352620) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851072 YP_001651363.1 CDS dgt NC_010278.1 352678 354003 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 352678..354003 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851456 YP_001651364.1 CDS hepA NC_010278.1 354175 357084 D transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 354175..357084 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851812 YP_001651365.1 CDS rluA NC_010278.1 357199 357867 D ribosomal large subunit pseudouridine synthase A 357199..357867 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851090 YP_001651366.1 CDS ampD NC_010278.1 358063 358611 R N-acetyl-anhydromuranmyl-L-alanine amidase complement(358063..358611) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851654 YP_001651367.1 CDS APJL_0332 NC_010278.1 358751 359593 D hypothetical protein 358751..359593 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851635 YP_001651368.1 CDS pyrE NC_010278.1 359680 360321 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 359680..360321 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851658 YP_001651369.1 CDS APJL_0334 NC_010278.1 360460 361548 D cobalamin-independent methionine synthase II 360460..361548 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850828 YP_001651370.1 CDS metC1 NC_010278.1 361625 362815 R catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase complement(361625..362815) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851624 YP_001651371.1 CDS dsbB NC_010278.1 362892 363431 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(362892..363431) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851468 YP_001651372.1 CDS nhaB NC_010278.1 363527 365068 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(363527..365068) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851337 YP_001651373.1 CDS fadR NC_010278.1 365233 365961 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 365233..365961 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851393 YP_001651374.1 CDS APJL_0339 NC_010278.1 365970 367040 D PhoH-like ATP-binding protein 365970..367040 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850941 YP_001651375.1 CDS APJL_0340 NC_010278.1 367079 368056 R hypothetical protein complement(367079..368056) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850880 YP_001651376.1 CDS prfB NC_010278.1 368127 369032 R peptide chain release factor 2 complement(368127..369032) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851614 YP_001651377.1 CDS APJL_0342 NC_010278.1 369148 369225 R hypothetical protein complement(369148..369225) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851314 YP_001651378.1 CDS selD NC_010278.1 369438 370409 D catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 369438..370409 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851555 YP_001651379.1 CDS ymfB NC_010278.1 370414 370869 D putative Nudix hydrolase ymfB 370414..370869 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851175 YP_001651380.1 CDS ubiH NC_010278.1 370879 372078 D UbiH protein (2-octaprenyl-6-methoxyphenol) 370879..372078 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851084 YP_001651381.1 CDS APJL_0346 NC_010278.1 372108 372584 R hypothetical protein complement(372108..372584) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850715 YP_001651382.1 CDS APJL_0347 NC_010278.1 372641 373396 R putative lipoprotein complement(372641..373396) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851657 YP_001651383.1 CDS hlpB NC_010278.1 373477 373956 R lipoprotein HlpB complement(373477..373956) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851275 YP_001651384.1 CDS visC NC_010278.1 374092 375237 R monoxygenase complement(374092..375237) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850858 YP_001651385.1 CDS APJL_0350 NC_010278.1 375362 376222 R hypothetical protein complement(375362..376222) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850793 YP_001651386.1 CDS ptsN1 NC_010278.1 376241 376768 R PTS system, nitrogen regulatory IIA-like protein complement(376241..376768) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850849 YP_001651387.1 CDS APJL_0352 NC_010278.1 376803 377528 R ABC transporter ATP-binding protein complement(376803..377528) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850940 YP_001651388.1 CDS APJL_0353 NC_010278.1 377538 378041 R hypothetical protein complement(377538..378041) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851451 YP_001651389.1 CDS APJL_0354 NC_010278.1 378066 378662 R hypothetical protein complement(378066..378662) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851392 YP_001651390.1 CDS ppc NC_010278.1 378822 381461 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(378822..381461) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851547 YP_001651391.1 CDS APJL_0356 NC_010278.1 381676 382479 R beta-propeller domain-containing protein complement(381676..382479) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851045 YP_001651392.1 CDS APJL_0357 NC_010278.1 382476 382925 R hypothetical protein complement(382476..382925) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851326 YP_001651393.1 CDS lemA NC_010278.1 382992 383576 R LemA protein complement(382992..383576) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851952 YP_001651394.1 CDS fruA NC_010278.1 383730 385391 R phosphotransferase system, fructose-specific IIC component complement(383730..385391) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851333 YP_001651395.1 CDS fruK NC_010278.1 385473 386420 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(385473..386420) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851375 YP_001651396.1 CDS ptsN2 NC_010278.1 386435 387943 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(386435..387943) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851294 YP_001651397.1 CDS glgB NC_010278.1 388204 390537 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 388204..390537 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851662 YP_001651398.1 CDS glgX NC_010278.1 390544 392529 D glycogen operon protein 390544..392529 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851366 YP_001651399.1 CDS glgC NC_010278.1 392545 393861 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 392545..393861 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851709 YP_001651400.1 CDS glgA NC_010278.1 393991 395400 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 393991..395400 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851754 YP_001651401.1 CDS APJL_0366 NC_010278.1 395430 397934 D glucan phosphorylase 395430..397934 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851777 YP_001651402.1 CDS ndk NC_010278.1 398046 398462 R nucleoside diphosphate kinase complement(398046..398462) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851870 YP_001651403.1 CDS metG NC_010278.1 398521 400569 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(398521..400569) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851781 YP_001651404.1 CDS menC NC_010278.1 400736 401698 D catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 400736..401698 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851939 YP_001651405.1 CDS APJL_0370 NC_010278.1 401734 401895 R hypothetical protein complement(401734..401895) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851765 YP_001651406.1 CDS rsuA NC_010278.1 402012 402704 D ribosomal small subunit pseudouridine synthase A 402012..402704 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851908 YP_001651407.1 CDS proP NC_010278.1 402704 403900 D Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 402704..403900 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851842 YP_001651408.1 CDS APJL_0373 NC_010278.1 403946 404332 R hypothetical protein complement(403946..404332) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851820 YP_001651409.1 CDS APJL_0374 NC_010278.1 404403 404972 R component of anaerobic dehydrogenase complement(404403..404972) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851883 YP_001651410.1 CDS nfo NC_010278.1 405030 405872 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 405030..405872 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851881 YP_001651411.1 CDS nlpC NC_010278.1 405993 406589 D lipoprotein NlpC 405993..406589 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851532 YP_001651412.1 CDS APJL_0377 NC_010278.1 406638 407093 R SOS-response transcriptional repressor complement(406638..407093) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850795 YP_001651413.1 CDS APJL_0378 NC_010278.1 407116 407241 D hypothetical protein 407116..407241 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851720 YP_001651414.1 CDS APJL_0379 NC_010278.1 407319 407705 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(407319..407705) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851943 YP_001651415.1 CDS ung NC_010278.1 407911 408588 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 407911..408588 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851900 YP_001651416.1 CDS APJL_0381 NC_010278.1 408686 409558 R hypothetical protein complement(408686..409558) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851802 YP_001651417.1 CDS APJL_0382 NC_010278.1 409653 412451 R serotype-specific antigen 1 complement(409653..412451) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851789 YP_001651418.1 CDS hrpA NC_010278.1 412603 416502 R involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA complement(412603..416502) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851831 YP_001651419.1 CDS APJL_0384 NC_010278.1 416638 417090 R hypothetical protein complement(416638..417090) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851917 YP_001651420.1 CDS grpE NC_010278.1 417287 417883 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(417287..417883) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851604 YP_001651421.1 CDS potD2 NC_010278.1 418128 419210 D spermidine/putrescine-binding periplasmic protein 418128..419210 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851376 YP_001651422.1 CDS norM NC_010278.1 419354 420745 D multidrug resistance protein 419354..420745 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852022 YP_001651423.1 CDS recB NC_010278.1 420761 424369 D exodeoxyribonuclease V subunit beta 420761..424369 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851967 YP_001651424.1 CDS lnt NC_010278.1 424447 425958 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(424447..425958) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851694 YP_001651425.1 CDS corC NC_010278.1 426033 426926 R magnesium and cobalt efflux protein complement(426033..426926) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851868 YP_001651426.1 CDS APJL_0391 NC_010278.1 427096 427698 D hypothetical protein 427096..427698 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851811 YP_001651427.1 CDS glpF NC_010278.1 427934 428716 D glycerol uptake facilitator protein 427934..428716 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852017 YP_001651428.1 CDS glpK NC_010278.1 428751 430262 D Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 428751..430262 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851759 YP_001651429.1 CDS lon NC_010278.1 430383 432791 R ATP-dependent protease LA complement(430383..432791) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852841 YP_001651430.1 CDS glpT NC_010278.1 432937 434253 R glycerol 3-phosphate transporter complement(432937..434253) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850846 YP_001651431.1 CDS glpA NC_010278.1 435924 437609 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 435924..437609 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851751 YP_001651432.1 CDS glpB NC_010278.1 437599 438885 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 437599..438885 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851892 YP_001651433.1 CDS glpC NC_010278.1 438882 440156 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 438882..440156 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851718 YP_001651434.1 CDS APJL_0401 NC_010278.1 440216 440407 R hypothetical protein complement(440216..440407) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851778 YP_001651435.1 CDS ribD NC_010278.1 440466 441560 D riboflavin-specific deaminase 440466..441560 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851935 YP_001651436.1 CDS ribE NC_010278.1 441685 442332 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 441685..442332 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851740 YP_001651437.1 CDS ribA NC_010278.1 442393 443598 D riboflavin biosynthesis protein ribA 442393..443598 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851822 YP_001651438.1 CDS ribH NC_010278.1 443709 444170 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 443709..444170 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851914 YP_001651439.1 CDS APJL_0406 NC_010278.1 444440 445228 D hypothetical protein 444440..445228 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851723 YP_001651440.1 CDS greB NC_010278.1 445357 445845 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB complement(445357..445845) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851799 YP_001651441.1 CDS APJL_0408 NC_010278.1 445855 446790 R phosphosugar isomerase complement(445855..446790) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852845 YP_001651442.1 CDS pepB NC_010278.1 446918 448210 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B complement(446918..448210) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851933 YP_001651443.1 CDS ompP4 NC_010278.1 448325 449140 R lipoprotein E complement(448325..449140) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851796 YP_001651444.1 CDS APJL_0411 NC_010278.1 449313 450251 D Na+-dependent transporter 449313..450251 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851797 YP_001651445.1 CDS acrA1 NC_010278.1 450331 451512 R membrane-fusion protein complement(450331..451512) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851898 YP_001651446.1 CDS APJL_0413 NC_010278.1 451609 452424 R HAD superfamily hydrolase complement(451609..452424) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851925 YP_001651447.1 CDS leuA NC_010278.1 453021 454562 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 453021..454562 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852832 YP_001651448.1 CDS rpoE NC_010278.1 454905 455483 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 454905..455483 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850859 YP_001651449.1 CDS rseA NC_010278.1 455503 456126 D sigma-E factor negative regulatory protein 455503..456126 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851767 YP_001651450.1 CDS rseC NC_010278.1 456354 456779 D sigma-E factor regulatory protein 456354..456779 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851227 YP_001651451.1 CDS lcfA NC_010278.1 456791 458482 D Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 456791..458482 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852846 YP_001651452.1 CDS upp NC_010278.1 458549 459175 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 458549..459175 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851680 YP_001651453.1 CDS ksgA NC_010278.1 459282 460151 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(459282..460151) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851899 YP_001651454.1 CDS surA NC_010278.1 460217 461167 R survival SurA-like protein complement(460217..461167) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852836 YP_001651455.1 CDS pyrR NC_010278.1 461248 461787 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase complement(461248..461787) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851681 YP_001651456.1 CDS waaE NC_010278.1 461803 463233 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(461803..463233) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852051 YP_001651457.1 CDS engA NC_010278.1 463347 464867 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(463347..464867) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852048 YP_001651458.1 CDS hemA NC_010278.1 465025 466335 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(465025..466335) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852041 YP_001651459.1 CDS dxr NC_010278.1 468896 470086 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 468896..470086 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852118 YP_001651460.1 CDS APJL_0429 NC_010278.1 470171 470959 R hypothetical protein complement(470171..470959) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852802 YP_001651461.1 CDS fabZ NC_010278.1 472065 472529 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(472065..472529) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852125 YP_001651462.1 CDS lpxD NC_010278.1 472598 473623 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(472598..473623) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852519 YP_001651463.1 CDS APJL_0434 NC_010278.1 473623 474429 R outer membrane protein complement(473623..474429) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852560 YP_001651464.1 CDS ompD NC_010278.1 474545 476926 R outer membrane protein D-15 complement(474545..476926) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852202 YP_001651465.1 CDS ecfE NC_010278.1 476988 478301 R putative zinc metalloprotease complement(476988..478301) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851809 YP_001651466.1 CDS cdsA NC_010278.1 478308 479177 R phosphatidate cytidylyltransferase complement(478308..479177) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852814 YP_001651467.1 CDS uppS NC_010278.1 479202 479915 R undecaprenyl pyrophosphate synthetase complement(479202..479915) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852809 YP_001651468.1 CDS gloB NC_010278.1 480088 480795 R hydroxyacylglutathione hydrolase complement(480088..480795) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852824 YP_001651469.1 CDS APJL_0440 NC_010278.1 480854 481771 R catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase complement(480854..481771) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852834 YP_001651470.1 CDS pgpB NC_010278.1 481774 482511 R phosphatidylglycerophosphatase B complement(481774..482511) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852833 YP_001651471.1 CDS APJL_0442 NC_010278.1 482570 482887 R putative RNA-binding protein complement(482570..482887) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852825 YP_001651472.1 CDS APJL_0443 NC_010278.1 483009 483767 D putative glycosyltransferase 483009..483767 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852842 YP_001651473.1 CDS waaQ NC_010278.1 484735 485772 R heptosyltransferase complement(484735..485772) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852829 YP_001651474.1 CDS argG NC_010278.1 486016 487347 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 486016..487347 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851696 YP_001651475.1 CDS rnhA NC_010278.1 487469 487930 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 487469..487930 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851414 YP_001651476.1 CDS cvpA NC_010278.1 488087 488590 D colicin V production protein 488087..488590 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852425 YP_001651477.1 CDS purF NC_010278.1 488604 490121 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 488604..490121 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852782 YP_001651478.1 CDS APJL_0451 NC_010278.1 490190 490645 R hypothetical protein complement(490190..490645) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851700 YP_001651479.1 CDS gdhA NC_010278.1 490744 492084 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(490744..492084) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851647 YP_001651480.1 CDS smpA NC_010278.1 492388 492732 R small protein A complement(492388..492732) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851949 YP_001651481.1 CDS ndpA NC_010278.1 492803 493804 R nucleoid-associated protein NdpA complement(492803..493804) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851373 YP_001651482.1 CDS APJL_0455 NC_010278.1 493897 494286 D putative translation initiation inhibitor 493897..494286 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851757 YP_001651483.1 CDS APJL_0456 NC_010278.1 494314 495051 D hypothetical protein 494314..495051 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851808 YP_001651484.1 CDS APJL_0457 NC_010278.1 495271 495471 R hypothetical protein complement(495271..495471) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851253 YP_001651485.1 CDS leuB NC_010278.1 495616 496698 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 495616..496698 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851950 YP_001651486.1 CDS msrB NC_010278.1 496822 497217 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(496822..497217) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851510 YP_001651487.1 CDS gapA NC_010278.1 497440 498444 D glyceraldehyde 3-phosphate dehydrogenase 497440..498444 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851715 YP_001651488.1 CDS mreB NC_010278.1 498640 499692 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 498640..499692 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851489 YP_001651489.1 CDS mreC NC_010278.1 499809 500858 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 499809..500858 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851600 YP_001651490.1 CDS mreD NC_010278.1 500858 501346 D rod shape-determining protein 500858..501346 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851745 YP_001651491.1 CDS APJL_0464 NC_010278.1 501413 502699 D recombination factor protein RarA 501413..502699 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851955 YP_001651492.1 CDS znuB NC_010278.1 502780 503565 D high-affinity zinc uptake system membrane protein 502780..503565 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851756 YP_001651493.1 CDS APJL_0466 NC_010278.1 503745 504542 D putative glutamine amidotransferase 503745..504542 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851176 YP_001651494.1 CDS metX NC_010278.1 504622 505698 R Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase complement(504622..505698) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850993 YP_001651495.1 CDS sanA NC_010278.1 505990 506679 D SanA protein 505990..506679 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851037 YP_001651496.1 CDS APJL_0471 NC_010278.1 517296 517994 R hypothetical protein complement(517296..517994) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851645 YP_001651497.1 CDS ykgF NC_010278.1 518123 519532 R iron-sulfur electron transport protein complement(518123..519532) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850842 YP_001651498.1 CDS ykgE NC_010278.1 519542 520267 R dehydrogenase complement(519542..520267) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851866 YP_001651499.1 CDS lctP NC_010278.1 520437 522032 R L-lactate permease complement(520437..522032) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851691 YP_001651500.1 CDS hns NC_010278.1 522501 522908 R DNA-binding protein H-NS complement(522501..522908) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851245 YP_001651501.1 CDS APJL_0476 NC_010278.1 523465 524982 D Na+/H+ antiporter 523465..524982 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851659 YP_001651502.1 CDS mglB NC_010278.1 525188 526159 D D-galactose transport system substrate-binding protein 525188..526159 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851854 YP_001651503.1 CDS sucD NC_010278.1 526294 527166 R succinyl-CoA synthetase alpha chain complement(526294..527166) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851052 YP_001651504.1 CDS sucC NC_010278.1 527169 528335 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(527169..528335) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851617 YP_001651505.1 CDS lapB NC_010278.1 528479 529345 R hypothetical protein complement(528479..529345) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851019 YP_001651506.1 CDS sucB NC_010278.1 529488 530717 R dihydrolipoamide succinyltransferase complement(529488..530717) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850910 YP_001651507.1 CDS sucA NC_010278.1 530837 533647 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(530837..533647) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850948 YP_001651508.1 CDS znuC NC_010278.1 533890 534690 R zinc ABC transporter ATP-binding protein complement(533890..534690) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851488 YP_001651509.1 CDS APJL_0484 NC_010278.1 534894 536384 D putative metalloprotease 534894..536384 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851628 YP_001651510.1 CDS dsbC NC_010278.1 536403 537098 D thiol:disulfide interchange protein 536403..537098 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851206 YP_001651511.1 CDS recJ NC_010278.1 537367 538905 D single-stranded-DNA-specific exonuclease 537367..538905 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851607 YP_001651512.1 CDS plpD NC_010278.1 539039 539890 D lipoprotein 539039..539890 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850934 YP_001651513.1 CDS APJL_0488 NC_010278.1 539972 540790 D phosphatase 539972..540790 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851477 YP_001651514.1 CDS narQ NC_010278.1 540790 542505 D nitrate/nitrite sensor protein NarQ 540790..542505 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850810 YP_001651515.1 CDS APJL_0490 NC_010278.1 542528 543046 D sortase and related acyltransferase 542528..543046 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851160 YP_001651516.1 CDS APJL_0491 NC_010278.1 543087 543683 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 543087..543683 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850822 YP_001651517.1 CDS APJL_0492 NC_010278.1 543711 544031 D hypothetical protein 543711..544031 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851707 YP_001651518.1 CDS fhs NC_010278.1 544137 545771 R catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase complement(544137..545771) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851109 YP_001651519.1 CDS APJL_0494 NC_010278.1 545917 546363 D hypothetical protein 545917..546363 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851141 YP_001651520.1 CDS APJL_0495 NC_010278.1 546453 547202 D NADP-dependent dehydrogenase 546453..547202 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851537 YP_001651521.1 CDS trpB NC_010278.1 547388 548578 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 547388..548578 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851615 YP_001651522.1 CDS trpA NC_010278.1 548580 549389 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 548580..549389 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851038 YP_001651523.1 CDS APJL_0498 NC_010278.1 549466 549759 R hypothetical protein complement(549466..549759) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850878 YP_001651524.1 CDS APJL_0499 NC_010278.1 549768 550052 R hypothetical protein complement(549768..550052) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851798 YP_001651525.1 CDS polA NC_010278.1 550347 553106 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 550347..553106 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851884 YP_001651526.1 CDS APJL_0501 NC_010278.1 553161 553358 D hypothetical protein 553161..553358 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851980 YP_001651527.1 CDS APJL_0502 NC_010278.1 553348 553641 D plasmid stabilization system protein 553348..553641 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851915 YP_001651528.1 CDS lolA NC_010278.1 553781 554422 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 553781..554422 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851747 YP_001651529.1 CDS APJL_0504 NC_010278.1 554497 554805 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 554497..554805 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851965 YP_001651530.1 CDS APJL_0505 NC_010278.1 554834 555595 D monofunctional biosynthetic peptidoglycan transglycosylase 554834..555595 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852020 YP_001651531.1 CDS APJL_0506 NC_010278.1 555665 556000 R putative gamma-carboxymuconolactone decarboxylase subunit complement(555665..556000) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851466 YP_001651532.1 CDS APJL_0507 NC_010278.1 556027 557031 R putative inner membrane transport protein complement(556027..557031) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850989 YP_001651533.1 CDS APJL_0508 NC_010278.1 557046 557387 R hypothetical protein complement(557046..557387) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851416 YP_001651534.1 CDS APJL_0509 NC_010278.1 557398 558741 R sulfide:quinone oxidoreductase complement(557398..558741) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851513 YP_001651535.1 CDS APJL_0510 NC_010278.1 558786 558998 R hypothetical protein complement(558786..558998) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850816 YP_001651536.1 CDS APJL_0511 NC_010278.1 559153 559440 D transcriptional regulator 559153..559440 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851053 YP_001651537.1 CDS APJL_0512 NC_010278.1 559515 560225 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 559515..560225 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851367 YP_001651538.1 CDS rimK NC_010278.1 560222 561136 D ribosomal protein S6 modification protein 560222..561136 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850899 YP_001651539.1 CDS APJL_0514 NC_010278.1 561171 561929 R hypothetical protein complement(561171..561929) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850876 YP_001651540.1 CDS rplY NC_010278.1 563699 563986 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 563699..563986 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851888 YP_001651541.1 CDS APJL_0518 NC_010278.1 564565 565206 D ABC transporter substrate-binding protein 564565..565206 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851721 YP_001651542.1 CDS APJL_0519 NC_010278.1 565329 566192 D putative nickel/cobalt efflux system 565329..566192 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851377 YP_001651543.1 CDS APJL_0520 NC_010278.1 566292 567740 D putative sodium/alanine symporter 566292..567740 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851021 YP_001651544.1 CDS APJL_0521 NC_010278.1 568131 568223 D hypothetical protein 568131..568223 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851230 YP_001651545.1 CDS nasD NC_010278.1 568337 568861 D ABC transporter ATP-binding protein 568337..568861 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850973 YP_001651546.1 CDS thiF NC_010278.1 568933 569154 D putative thiamine biosynthesis protein 568933..569154 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851448 YP_001651547.1 CDS thiS NC_010278.1 569230 569430 D thiamine biosynthesis protein 569230..569430 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850862 YP_001651548.1 CDS thiG1 NC_010278.1 569511 569732 D putative thiamine biosynthesis protein 569511..569732 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850885 YP_001651549.1 CDS thiG2 NC_010278.1 569866 570276 D putative thiamine biosynthesis protein 569866..570276 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851508 YP_001651550.1 CDS thiH NC_010278.1 570286 571431 D thiamine biosynthesis protein 570286..571431 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851039 YP_001651551.1 CDS APJL_0528 NC_010278.1 571458 572108 D putative transcription activator 571458..572108 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850767 YP_001651552.1 CDS APJL_0529 NC_010278.1 572131 572931 D sulfonate/nitrate/taurine transport system substrate-binding protein 572131..572931 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851036 YP_001651553.1 CDS lepA NC_010278.1 574299 576098 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 574299..576098 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851042 YP_001651554.1 CDS lepB NC_010278.1 576203 577162 D signal peptidase I 576203..577162 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851087 YP_001651555.1 CDS rnc NC_010278.1 577258 577929 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 577258..577929 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851559 YP_001651556.1 CDS era NC_010278.1 577999 578913 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 577999..578913 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851688 YP_001651557.1 CDS recO NC_010278.1 578924 579646 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 578924..579646 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851352 YP_001651558.1 CDS tadG NC_010278.1 579740 581329 R Flp pilus assembly protein complement(579740..581329) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850791 YP_001651559.1 CDS tadF NC_010278.1 581353 582117 R tight adherence protein F complement(581353..582117) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851271 YP_001651560.1 CDS tadE NC_010278.1 581921 582406 R tight adherence protein E complement(581921..582406) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851517 YP_001651561.1 CDS tadD NC_010278.1 582409 583161 R Flp pilus assembly protein complement(582409..583161) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851384 YP_001651562.1 CDS tadC NC_010278.1 583151 583996 R Flp pilus assembly protein complement(583151..583996) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851516 YP_001651563.1 CDS tadB NC_010278.1 583996 584883 R Flp pilus assembly protein complement(583996..584883) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851687 YP_001651564.1 CDS tadA NC_010278.1 584883 586160 R tight adherence protein A complement(584883..586160) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851071 YP_001651565.1 CDS tadZ NC_010278.1 586169 587296 R Flp pilus assembly protein, ATPase complement(586169..587296) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851415 YP_001651566.1 CDS rcpB NC_010278.1 587459 587962 R rough colony protein B complement(587459..587962) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850818 YP_001651567.1 CDS rcpA NC_010278.1 587959 589347 R Flp pilus assembly protein, secretin complement(587959..589347) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850999 YP_001651568.1 CDS APJL_0549 NC_010278.1 589337 589561 R hypothetical protein complement(589337..589561) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850933 YP_001651569.1 CDS APJL_0550 NC_010278.1 589522 589779 D hypothetical protein 589522..589779 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851303 YP_001651570.1 CDS APJL_0551 NC_010278.1 589830 591329 D ATPase 589830..591329 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851371 YP_001651571.1 CDS afuA2 NC_010278.1 591526 592557 D iron(III) transport system substrate-binding protein 591526..592557 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850841 YP_001651572.1 CDS afuB2 NC_010278.1 592688 594688 D iron(III) transport system permease 592688..594688 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851436 YP_001651573.1 CDS rpsB NC_010278.1 599064 599780 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 599064..599780 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851800 YP_001651574.1 CDS tsf NC_010278.1 599876 600727 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 599876..600727 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851872 YP_001651575.1 CDS APJL_0561 NC_010278.1 600856 602409 R membrane protein complement(600856..602409) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851910 YP_001651576.1 CDS pyrH NC_010278.1 602521 603234 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 602521..603234 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851922 YP_001651577.1 CDS frr NC_010278.1 603418 603975 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 603418..603975 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851928 YP_001651578.1 CDS APJL_0564 NC_010278.1 604053 605453 R transcriptional regulator complement(604053..605453) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851758 YP_001651579.1 CDS APJL_0565 NC_010278.1 605540 606427 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 605540..606427 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851916 YP_001651580.1 CDS APJL_0566 NC_010278.1 606427 607002 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 606427..607002 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851843 YP_001651581.1 CDS APJL_0567 NC_010278.1 607076 607666 R tRNA-specific adenosine deaminase complement(607076..607666) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851907 YP_001651582.1 CDS deaD NC_010278.1 607683 609542 R cold-shock DEAD box protein-A complement(607683..609542) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851790 YP_001651583.1 CDS nlpI NC_010278.1 609764 610705 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(609764..610705) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851920 YP_001651584.1 CDS pnp NC_010278.1 610766 612913 R polynucleotide phosphorylase/polyadenylase complement(610766..612913) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851945 YP_001651585.1 CDS parC NC_010278.1 613251 615461 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 613251..615461 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851909 YP_001651586.1 CDS mukF NC_010278.1 615601 616932 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 615601..616932 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851947 YP_001651587.1 CDS mukE NC_010278.1 617012 617725 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 617012..617725 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851894 YP_001651588.1 CDS mukB NC_010278.1 617746 622236 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 617746..622236 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851760 YP_001651589.1 CDS APJL_0575 NC_010278.1 622313 623488 D sugar efflux transporter 622313..623488 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851983 YP_001651590.1 CDS APJL_0576 NC_010278.1 623540 625279 R putative sulfatase complement(623540..625279) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851673 YP_001651591.1 CDS APJL_0577 NC_010278.1 625282 625503 R hypothetical protein complement(625282..625503) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852016 YP_001651592.1 CDS APJL_0578 NC_010278.1 625713 626291 D putative HTH-type transcriptional regulator 625713..626291 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851839 YP_001651593.1 CDS APJL_0579 NC_010278.1 626324 627529 D membrane-fusion protein 626324..627529 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851937 YP_001651594.1 CDS APJL_0580 NC_010278.1 627542 630661 D acriflavine resistance protein 627542..630661 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851846 YP_001651595.1 CDS glmU NC_010278.1 630879 632243 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 630879..632243 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851833 YP_001651596.1 CDS APJL_0582 NC_010278.1 632350 632667 R hypothetical protein complement(632350..632667) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851896 YP_001651597.1 CDS APJL_0583 NC_010278.1 632671 633291 R exopolysaccharide biosynthesis protein complement(632671..633291) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851837 YP_001651598.1 CDS yhxB NC_010278.1 633585 635243 D phosphomannomutase 633585..635243 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851753 YP_001651599.1 CDS guaA NC_010278.1 635325 636896 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(635325..636896) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851973 YP_001651600.1 CDS APJL_0586 NC_010278.1 636911 637225 R hypothetical protein complement(636911..637225) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851844 YP_001651601.1 CDS guaB NC_010278.1 637315 638778 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(637315..638778) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852008 YP_001651602.1 CDS rrmJ NC_010278.1 639031 639657 D Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 639031..639657 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851946 YP_001651603.1 CDS ftsH NC_010278.1 639761 641683 D cell division protein 639761..641683 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851961 YP_001651604.1 CDS tyrP1 NC_010278.1 641990 643135 D tyrosine-specific transport protein 641990..643135 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851815 YP_001651605.1 CDS tyrP2 NC_010278.1 643300 644448 D tyrosine-specific transport protein 643300..644448 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851987 YP_001651606.1 CDS glnD NC_010278.1 644555 647107 D PII uridylyl-transferase 644555..647107 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851743 YP_001651607.1 CDS APJL_0593 NC_010278.1 647140 647538 R hypothetical protein complement(647140..647538) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851885 YP_001651608.1 CDS rplM NC_010278.1 647844 648272 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 647844..648272 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851990 YP_001651609.1 CDS rpsI NC_010278.1 648289 648684 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 648289..648684 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852006 YP_001651610.1 CDS APJL_0596 NC_010278.1 648806 649588 D hypothetical protein 648806..649588 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852830 YP_001651611.1 CDS APJL_0597 NC_010278.1 649588 650133 D hypothetical protein 649588..650133 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851991 YP_001651612.1 CDS fieF NC_010278.1 650159 651082 D cation-efflux pump FieF 650159..651082 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851717 YP_001651613.1 CDS APJL_0599 NC_010278.1 651063 651833 D hypothetical protein 651063..651833 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851652 YP_001651614.1 CDS APJL_0600 NC_010278.1 651932 653257 D proton glutamate symport protein 651932..653257 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851819 YP_001651615.1 CDS APJL_0601 NC_010278.1 653359 654021 R putative NAD(P)H nitroreductase complement(653359..654021) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851932 YP_001651616.1 CDS pheS NC_010278.1 654303 655289 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 654303..655289 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851847 YP_001651617.1 CDS pheT NC_010278.1 655387 657774 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 655387..657774 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852012 YP_001651618.1 CDS ihfA NC_010278.1 657792 658088 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 657792..658088 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851832 YP_001651619.1 CDS APJL_0605 NC_010278.1 658148 658672 D lipoprotein 658148..658672 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851918 YP_001651620.1 CDS APJL_0606 NC_010278.1 658945 659292 R transposase complement(658945..659292) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852032 YP_001651621.1 CDS APJL_0607 NC_010278.1 659316 659639 R putative transposase-like protein complement(659316..659639) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851157 YP_001651622.1 CDS APJL_0608 NC_010278.1 659645 660154 R transposase and inactivated derivative complement(659645..660154) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851803 YP_001651623.1 CDS bioD NC_010278.1 660227 660946 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(660227..660946) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851856 YP_001651624.1 CDS mlc NC_010278.1 661000 662190 R transcriptional regulator/sugar kinase complement(661000..662190) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851829 YP_001651625.1 CDS rnd NC_010278.1 662369 663484 D ribonuclease D 662369..663484 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851762 YP_001651626.1 CDS lrp NC_010278.1 663569 664051 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 663569..664051 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852000 YP_001651627.1 CDS ftsK NC_010278.1 664117 666933 D cell division protein 664117..666933 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851880 YP_001651628.1 CDS APJL_0614 NC_010278.1 667118 667981 D hypothetical protein 667118..667981 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851792 YP_001651629.1 CDS aroG NC_010278.1 668104 669177 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 668104..669177 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851677 YP_001651630.1 CDS APJL_0616 NC_010278.1 669281 669973 D M22 peptidase-like protein 669281..669973 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850990 YP_001651631.1 CDS tdk NC_010278.1 670415 670906 R thymidine kinase complement(670415..670906) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852038 YP_001651632.1 CDS APJL_0618 NC_010278.1 671056 671274 R hypothetical protein complement(671056..671274) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851874 YP_001651633.1 CDS glpX NC_010278.1 671459 672457 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 671459..672457 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852070 YP_001651634.1 CDS APJL_0620 NC_010278.1 672520 673293 R hypothetical protein complement(672520..673293) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851911 YP_001651635.1 CDS APJL_0621 NC_010278.1 673381 675303 R putative ABC transporter ATP-binding protein complement(673381..675303) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851679 YP_001651636.1 CDS cpxA NC_010278.1 675447 676847 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(675447..676847) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852056 YP_001651637.1 CDS cpxR NC_010278.1 676912 677586 R transcriptional regulatory protein CpxR complement(676912..677586) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852102 YP_001651638.1 CDS mazG NC_010278.1 677680 678459 R MazG protein complement(677680..678459) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851730 YP_001651639.1 CDS APJL_0625 NC_010278.1 678593 678694 D hypothetical protein 678593..678694 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852082 YP_001651640.1 CDS accD NC_010278.1 678798 679691 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 678798..679691 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852101 YP_001651641.1 CDS folC NC_010278.1 679748 681052 D folylpolyglutamate synthase/dihydrofolate synthase 679748..681052 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852848 YP_001651642.1 CDS APJL_0628 NC_010278.1 681436 681897 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 681436..681897 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852785 YP_001651643.1 CDS nusA NC_010278.1 681914 683395 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 681914..683395 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852784 YP_001651644.1 CDS infB NC_010278.1 683417 685942 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 683417..685942 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852781 YP_001651645.1 CDS rbfA NC_010278.1 686114 686497 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 686114..686497 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852780 YP_001651646.1 CDS truB NC_010278.1 686498 687415 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 686498..687415 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852779 YP_001651647.1 CDS APJL_0633 NC_010278.1 687461 688549 D membrane-bound lytic murein transglycosylase B 687461..688549 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852778 YP_001651648.1 CDS APJL_0634 NC_010278.1 688678 688863 D hypothetical protein 688678..688863 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852775 YP_001651649.1 CDS pta NC_010278.1 688983 691121 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(688983..691121) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852774 YP_001651650.1 CDS ackA NC_010278.1 691177 692385 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(691177..692385) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852773 YP_001651651.1 CDS cpdB NC_010278.1 692682 694658 D periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 692682..694658 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852772 YP_001651652.1 CDS ompP2B NC_010278.1 695602 696678 R outer membrane protein P2-like protein complement(695602..696678) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852769 YP_001651653.1 CDS APJL_0640 NC_010278.1 697136 697669 D hypothetical protein 697136..697669 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852768 YP_001651654.1 CDS galU NC_010278.1 697701 698588 R UTP-glucose-1-phosphate uridylyltransferase complement(697701..698588) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852767 YP_001651655.1 CDS manB NC_010278.1 698701 700059 R phosphomannomutase complement(698701..700059) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852766 YP_001651656.1 CDS csrA NC_010278.1 700094 700288 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(700094..700288) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852764 YP_001651657.1 CDS alaS NC_010278.1 700367 702991 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(700367..702991) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852763 YP_001651658.1 CDS uspA NC_010278.1 703217 703642 R universal stress protein A complement(703217..703642) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852762 YP_001651659.1 CDS hlyX NC_010278.1 703906 704673 D Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 703906..704673 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852761 YP_001651660.1 CDS sspB NC_010278.1 704772 705188 R ClpXP protease specificity-enhancing factor complement(704772..705188) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852760 YP_001651661.1 CDS sspA NC_010278.1 705188 705832 R stringent starvation protein A complement(705188..705832) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852759 YP_001651662.1 CDS purE NC_010278.1 706051 706545 D phosphoribosylaminoimidazole carboxylasecatalytic subunit 706051..706545 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852758 YP_001651663.1 CDS APJL_0650 NC_010278.1 706555 707520 D L-asparaginase 706555..707520 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852757 YP_001651664.1 CDS purK NC_010278.1 707630 708718 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 707630..708718 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852756 YP_001651665.1 CDS aspC NC_010278.1 708850 710046 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 708850..710046 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852755 YP_001651666.1 CDS pepP NC_010278.1 710230 711516 R Xaa-Pro aminopeptidase complement(710230..711516) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852754 YP_001651667.1 CDS APJL_0654 NC_010278.1 711644 714661 R type III restriction-modification system restriction subunit complement(711644..714661) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852753 YP_001651668.1 CDS APJL_0655 NC_010278.1 714681 716537 R type III restriction-modification system methyltransferase complement(714681..716537) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852752 YP_001651669.1 CDS APJL_0656 NC_010278.1 716552 717244 R hypothetical protein complement(716552..717244) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852751 YP_001651670.1 CDS APJL_0657 NC_010278.1 717247 720522 R hypothetical protein complement(717247..720522) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852749 YP_001651671.1 CDS APJL_0658 NC_010278.1 720648 721871 R hypothetical protein complement(720648..721871) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852748 YP_001651672.1 CDS APJL_0659 NC_010278.1 722007 722396 R hypothetical protein complement(722007..722396) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852747 YP_001651673.1 CDS APJL_0660 NC_010278.1 722397 722657 R hypothetical protein complement(722397..722657) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852746 YP_001651674.1 CDS APJL_0661 NC_010278.1 723003 723839 D hypothetical protein 723003..723839 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852745 YP_001651675.1 CDS uvrB NC_010278.1 723871 725892 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(723871..725892) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852744 YP_001651676.1 CDS APJL_0663 NC_010278.1 726069 726881 D lipoprotein precursor 726069..726881 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852743 YP_001651677.1 CDS ywbN NC_010278.1 726896 728086 D putative peroxidase YwbN 726896..728086 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852740 YP_001651678.1 CDS APJL_0665 NC_010278.1 728097 728717 D high-affinity Fe2+/Pb2+ permease 728097..728717 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852739 YP_001651679.1 CDS trpH NC_010278.1 728757 729575 R metal-dependent phosphoesterase complement(728757..729575) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852737 YP_001651680.1 CDS APJL_0667 NC_010278.1 729579 730169 R Mug protein complement(729579..730169) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852736 YP_001651681.1 CDS sbcB NC_010278.1 730186 731730 R Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I complement(730186..731730) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852735 YP_001651682.1 CDS eriC NC_010278.1 731972 733252 R chloride channel protein complement(731972..733252) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852734 YP_001651683.1 CDS asnC NC_010278.1 733586 734989 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 733586..734989 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852733 YP_001651684.1 CDS APJL_0671 NC_010278.1 735093 736094 R hypothetical protein complement(735093..736094) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852732 YP_001651685.1 CDS APJL_0672 NC_010278.1 736181 736744 R hypothetical protein complement(736181..736744) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852731 YP_001651686.1 CDS efp NC_010278.1 736822 737460 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 736822..737460 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852729 YP_001651687.1 CDS glnS NC_010278.1 737615 739285 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 737615..739285 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852728 YP_001651688.1 CDS APJL_0675 NC_010278.1 739288 739482 D hypothetical protein 739288..739482 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852727 YP_001651689.1 CDS APJL_0676 NC_010278.1 739515 740906 R putative transport protein complement(739515..740906) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852726 YP_001651690.1 CDS APJL_0677 NC_010278.1 741087 743195 R putative soluble lytic murein transglycosylase complement(741087..743195) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852725 YP_001651691.1 CDS hpt NC_010278.1 743304 743843 R hypoxanthine phosphoribosyl transferase complement(743304..743843) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852723 YP_001651692.1 CDS metB NC_010278.1 743947 745083 R catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase complement(743947..745083) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852721 YP_001651693.1 CDS dapB NC_010278.1 745197 746006 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(745197..746006) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852720 YP_001651694.1 CDS APJL_0681 NC_010278.1 746065 746640 R hypothetical protein complement(746065..746640) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852719 YP_001651695.1 CDS APJL_0682 NC_010278.1 746640 747557 R hypothetical protein complement(746640..747557) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852718 YP_001651696.1 CDS mtfA NC_010278.1 747582 748667 R putative RNA 2'-O-ribose methyltransferase complement(747582..748667) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852717 YP_001651697.1 CDS APJL_0684 NC_010278.1 749039 749443 R membrane protein complement(749039..749443) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852716 YP_001651698.1 CDS dld NC_010278.1 749547 751238 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 749547..751238 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852715 YP_001651699.1 CDS torZ NC_010278.1 751376 753850 R trimethylamine-N-oxide reductase 2 complement(751376..753850) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852714 YP_001651700.1 CDS torY NC_010278.1 754046 755164 R cytochrome c-type protein TorY complement(754046..755164) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852713 YP_001651701.1 CDS moaA NC_010278.1 755516 756538 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 755516..756538 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852711 YP_001651702.1 CDS moaC NC_010278.1 756823 757299 D molybdenum cofactor biosynthesis protein C 756823..757299 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852709 YP_001651703.1 CDS moaD NC_010278.1 757321 757566 D molybdopterin converting factor, small subunit 757321..757566 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852708 YP_001651704.1 CDS moaE NC_010278.1 757567 758022 D molybdopterin converting factor subunit 2 757567..758022 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852706 YP_001651705.1 CDS APJL_0692 NC_010278.1 758103 758594 D putative metalloprotease 758103..758594 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852704 YP_001651706.1 CDS APJL_0693 NC_010278.1 758606 760396 D acetyltransferase 758606..760396 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852703 YP_001651707.1 CDS topA NC_010278.1 760460 763069 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(760460..763069) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852702 YP_001651708.1 CDS APJL_0695 NC_010278.1 763211 764107 D putative HTH-type transcriptional regulator 763211..764107 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852701 YP_001651709.1 CDS argA NC_010278.1 764199 765512 R catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase complement(764199..765512) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852700 YP_001651710.1 CDS aroA NC_010278.1 765660 766958 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(765660..766958) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852699 YP_001651711.1 CDS hisC1 NC_010278.1 766972 768066 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(766972..768066) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852697 YP_001651712.1 CDS metC2 NC_010278.1 768266 769534 R putative cystathionine beta-lyase complement(768266..769534) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852695 YP_001651713.1 CDS serC NC_010278.1 769740 770828 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(769740..770828) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852693 YP_001651714.1 CDS APJL_0703 NC_010278.1 773891 777208 R potential type III restriction enzyme complement(773891..777208) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852690 YP_001651715.1 CDS APJL_0704 NC_010278.1 777610 780498 R methylation subunit, type III restriction-modification system complement(777610..780498) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852689 YP_001651716.1 CDS APJL_0705 NC_010278.1 780823 781695 R putative HTH-type transcriptional regulator complement(780823..781695) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852688 YP_001651717.1 CDS APJL_0706 NC_010278.1 781705 782172 R hypothetical protein complement(781705..782172) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852687 YP_001651718.1 CDS ppx NC_010278.1 782373 783881 R exopolyphosphatase complement(782373..783881) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852686 YP_001651719.1 CDS APJL_0708 NC_010278.1 784090 784425 D hypothetical protein 784090..784425 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852684 YP_001651720.1 CDS nrdR NC_010278.1 786396 786845 R transcriptional regulator NrdR complement(786396..786845) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852682 YP_001651721.1 CDS APJL_0712 NC_010278.1 786845 787132 R hypothetical protein complement(786845..787132) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852680 YP_001651722.1 CDS dnaB2 NC_010278.1 787104 788585 R replicative DNA helicase complement(787104..788585) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852678 YP_001651723.1 CDS APJL_0714 NC_010278.1 788765 789673 D enterochelin ABC transporter,periplasmic protein 788765..789673 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852677 YP_001651724.1 CDS APJL_0715 NC_010278.1 789760 790707 D iron(III) transport system permease 789760..790707 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852675 YP_001651725.1 CDS APJL_0716 NC_010278.1 790707 791648 D iron(III) transport system permease 790707..791648 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852674 YP_001651726.1 CDS APJL_0717 NC_010278.1 791650 792408 D iron(III) transport system ATP-binding protein 791650..792408 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852673 YP_001651727.1 CDS APJL_0718 NC_010278.1 792597 793277 D phosphate transport regulator 792597..793277 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852671 YP_001651728.1 CDS APJL_0719 NC_010278.1 793287 794549 D putative phosphate permease 793287..794549 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852670 YP_001651729.1 CDS APJL_0720 NC_010278.1 794613 795218 D SH3 domain-containing protein 794613..795218 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852669 YP_001651730.1 CDS APJL_0721 NC_010278.1 795271 795498 R hypothetical protein complement(795271..795498) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852667 YP_001651731.1 CDS APJL_0722 NC_010278.1 795505 796020 R hypothetical protein complement(795505..796020) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852666 YP_001651732.1 CDS tgt NC_010278.1 796093 797241 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(796093..797241) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852665 YP_001651733.1 CDS APJL_0724 NC_010278.1 797313 797489 R hypothetical protein complement(797313..797489) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852664 YP_001651734.1 CDS APJL_0725 NC_010278.1 797564 798136 D hypothetical protein 797564..798136 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852663 YP_001651735.1 CDS cspD NC_010278.1 798244 798450 D cold shock-like protein CspD 798244..798450 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852662 YP_001651736.1 CDS ilvI NC_010278.1 799600 801324 D acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 3 catalytic subunit 799600..801324 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852660 YP_001651737.1 CDS ilvH NC_010278.1 801317 801808 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 801317..801808 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852658 YP_001651738.1 CDS pmbA NC_010278.1 802078 803427 R antibiotic maturation factor PmbA complement(802078..803427) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852657 YP_001651739.1 CDS APJL_0732 NC_010278.1 803535 804065 D hypothetical protein 803535..804065 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852656 YP_001651740.1 CDS APJL_0733 NC_010278.1 804110 804481 D hypothetical protein 804110..804481 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852654 YP_001651741.1 CDS ubiX NC_010278.1 804664 805113 D 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 804664..805113 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852651 YP_001651742.1 CDS yqgA NC_010278.1 805116 805829 D putative inner membrane protein 805116..805829 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852649 YP_001651743.1 CDS APJL_0736 NC_010278.1 805876 806325 D hypothetical protein 805876..806325 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852648 YP_001651744.1 CDS APJL_0737 NC_010278.1 806398 806709 R involved in start site selection during the initiation of translation; translation initiation factor Sui1 complement(806398..806709) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852647 YP_001651745.1 CDS pyrF NC_010278.1 806789 807481 R type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(806789..807481) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852646 YP_001651746.1 CDS APJL_0739 NC_010278.1 807506 808702 R tetratricopeptide repeat protein complement(807506..808702) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852645 YP_001651747.1 CDS APJL_0740 NC_010278.1 808702 808992 R hypothetical protein complement(808702..808992) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852644 YP_001651748.1 CDS ihfB NC_010278.1 809061 809342 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(809061..809342) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852643 YP_001651749.1 CDS rpsA NC_010278.1 809416 811080 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(809416..811080) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852642 YP_001651750.1 CDS cmkA NC_010278.1 811177 811851 R cytidylate kinase complement(811177..811851) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852640 YP_001651751.1 CDS degS NC_010278.1 812097 812912 R protease DegS complement(812097..812912) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852639 YP_001651752.1 CDS secG NC_010278.1 813161 813487 R preprotein translocase subunit SecG complement(813161..813487) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852637 YP_001651753.1 CDS topB2 NC_010278.1 813619 815535 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(813619..815535) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852636 YP_001651754.1 CDS APJL_0747 NC_010278.1 815718 817163 D alkaline phosphatase 815718..817163 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852635 YP_001651755.1 CDS mepA NC_010278.1 817212 818042 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(817212..818042) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852634 YP_001651756.1 CDS aroC NC_010278.1 818137 819219 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(818137..819219) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852632 YP_001651757.1 CDS kefA1 NC_010278.1 819241 822549 R small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA complement(819241..822549) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852631 YP_001651758.1 CDS kefA2 NC_010278.1 822567 825911 R small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA complement(822567..825911) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852630 YP_001651759.1 CDS menE NC_010278.1 825892 827322 R O-succinylbenzoic acid--CoA ligase complement(825892..827322) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852629 YP_001651760.1 CDS seqA NC_010278.1 827340 827900 R negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA complement(827340..827900) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852628 YP_001651761.1 CDS APJL_0754 NC_010278.1 828024 828809 D putative esterase/lipase 828024..828809 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852626 YP_001651762.1 CDS APJL_0755 NC_010278.1 828817 829542 D SAM-dependent methyltransferase 828817..829542 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852624 YP_001651763.1 CDS fabI NC_010278.1 829746 830534 D enoyl-(acyl carrier protein) reductase 829746..830534 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852623 YP_001651764.1 CDS APJL_0757 NC_010278.1 830729 831007 D hypothetical protein 830729..831007 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852622 YP_001651765.1 CDS APJL_0758 NC_010278.1 830982 831260 D hypothetical protein 830982..831260 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852620 YP_001651766.1 CDS rnb NC_010278.1 831392 833368 D Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 831392..833368 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852619 YP_001651767.1 CDS lrgA1 NC_010278.1 833443 833814 D putative effector of murein hydrolase LrgA 833443..833814 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852617 YP_001651768.1 CDS lrgB NC_010278.1 833811 834497 D putative effector of murein hydrolase 833811..834497 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852615 YP_001651769.1 CDS apaH NC_010278.1 834522 835334 D hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 834522..835334 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852614 YP_001651770.1 CDS APJL_0763 NC_010278.1 835523 835765 R hypothetical protein complement(835523..835765) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852610 YP_001651771.1 CDS APJL_0764 NC_010278.1 835933 836688 D SAM-dependent methyltransferase 835933..836688 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852609 YP_001651772.1 CDS perM NC_010278.1 836747 837808 D putative permease 836747..837808 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852607 YP_001651773.1 CDS APJL_0766 NC_010278.1 837838 838767 D hypothetical protein 837838..838767 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852605 YP_001651774.1 CDS queA NC_010278.1 838815 839900 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 838815..839900 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852604 YP_001651775.1 CDS rec2 NC_010278.1 839934 842228 R recombination protein 2 complement(839934..842228) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852603 YP_001651776.1 CDS APJL_0769 NC_010278.1 842328 843542 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(842328..843542) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852602 YP_001651777.1 CDS dgkA NC_010278.1 843791 844153 D diacylglycerol kinase 843791..844153 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852601 YP_001651778.1 CDS ushA NC_010278.1 844234 845877 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 844234..845877 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852599 YP_001651779.1 CDS APJL_0772 NC_010278.1 845956 846255 D hypothetical protein 845956..846255 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852598 YP_001651780.1 CDS APJL_0773 NC_010278.1 846384 846749 D hypothetical protein 846384..846749 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852597 YP_001651781.1 CDS lpdA NC_010278.1 847458 848882 R E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(847458..848882) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852591 YP_001651782.1 CDS aceF NC_010278.1 848978 850876 R E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase complement(848978..850876) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852589 YP_001651783.1 CDS aceE NC_010278.1 850936 853590 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(850936..853590) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852588 YP_001651784.1 CDS pyrD NC_010278.1 853945 854952 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(853945..854952) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852587 YP_001651785.1 CDS prsA NC_010278.1 855026 855976 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(855026..855976) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852586 YP_001651786.1 CDS ipk NC_010278.1 855988 856845 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(855988..856845) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852585 YP_001651787.1 CDS lolB NC_010278.1 856855 857487 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(856855..857487) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852584 YP_001651788.1 CDS msbA NC_010278.1 857616 859364 R involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease complement(857616..859364) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852583 YP_001651789.1 CDS APJL_0782 NC_010278.1 859469 860155 R putative effector of murein hydrolase complement(859469..860155) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852582 YP_001651790.1 CDS lrgA2 NC_010278.1 860165 860524 R putative effector of murein hydrolase LrgA complement(860165..860524) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852581 YP_001651791.1 CDS APJL_0784 NC_010278.1 860591 862513 R ATP-dependent helicase complement(860591..862513) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852580 YP_001651792.1 CDS APJL_0785 NC_010278.1 862635 862847 D hypothetical protein 862635..862847 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852579 YP_001651793.1 CDS uvrA NC_010278.1 862986 865814 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(862986..865814) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852578 YP_001651794.1 CDS ssb NC_010278.1 865965 866489 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 865965..866489 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852577 YP_001651795.1 CDS APJL_0788 NC_010278.1 866653 867471 R hypothetical protein complement(866653..867471) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852575 YP_001651796.1 CDS APJL_0789 NC_010278.1 867794 869785 R hypothetical protein complement(867794..869785) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852574 YP_001651797.1 CDS APJL_0790 NC_010278.1 869782 870210 R hypothetical protein complement(869782..870210) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852573 YP_001651798.1 CDS APJL_0791 NC_010278.1 870207 871295 R hypothetical protein complement(870207..871295) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852572 YP_001651799.1 CDS APJL_0792 NC_010278.1 871396 872688 R putative ATPase complement(871396..872688) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852570 YP_001651800.1 CDS APJL_0793 NC_010278.1 872996 873883 R transcriptional regulator complement(872996..873883) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852568 YP_001651801.1 CDS APJL_0794 NC_010278.1 873988 874962 D dioxygenase 873988..874962 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852567 YP_001651802.1 CDS APJL_0798 NC_010278.1 876908 877675 R hypothetical protein complement(876908..877675) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852564 YP_001651803.1 CDS sapD NC_010278.1 877758 878732 R peptide transport system ATP binding protein complement(877758..878732) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852563 YP_001651804.1 CDS sapC NC_010278.1 878809 879696 R peptide transport system permease complement(878809..879696) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852562 YP_001651805.1 CDS sapB NC_010278.1 879686 880648 R peptide transport system permease complement(879686..880648) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852559 YP_001651806.1 CDS sapA NC_010278.1 880648 882345 R peptide transport periplasmic protein complement(880648..882345) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852558 YP_001651807.1 CDS tyrR NC_010278.1 882355 883503 R transcriptional regulatory protein complement(882355..883503) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852557 YP_001651808.1 CDS gmhA NC_010278.1 883708 884292 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 883708..884292 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852556 YP_001651809.1 CDS pckA NC_010278.1 884525 886135 R PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(884525..886135) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852554 YP_001651810.1 CDS ftsB NC_010278.1 886408 886686 D cell division protein FtsB 886408..886686 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852552 YP_001651811.1 CDS ispD NC_010278.1 886702 887388 D 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 886702..887388 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852551 YP_001651812.1 CDS ispF NC_010278.1 887385 887861 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 887385..887861 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852550 YP_001651813.1 CDS APJL_0809 NC_010278.1 887895 888014 R hypothetical protein complement(887895..888014) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852548 YP_001651814.1 CDS APJL_0810 NC_010278.1 888530 890506 R hypothetical protein complement(888530..890506) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852547 YP_001651815.1 CDS ycbX NC_010278.1 890544 891332 R putative Fe-S protein complement(890544..891332) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852546 YP_001651816.1 CDS APJL_0812 NC_010278.1 891477 891701 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 891477..891701 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852545 YP_001651817.1 CDS ispA NC_010278.1 891710 892603 D geranyltranstransferase 891710..892603 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852544 YP_001651818.1 CDS APJL_0814 NC_010278.1 892687 893031 R hypothetical protein complement(892687..893031) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852543 YP_001651819.1 CDS lysS NC_010278.1 893132 894634 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(893132..894634) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852542 YP_001651820.1 CDS cafA NC_010278.1 894769 896244 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(894769..896244) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852541 YP_001651821.1 CDS APJL_0817 NC_010278.1 896474 898237 D hypothetical protein 896474..898237 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852540 YP_001651822.1 CDS APJL_0818 NC_010278.1 898270 900882 R type III restriction enzyme complement(898270..900882) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852538 YP_001651823.1 CDS APJL_0819 NC_010278.1 901021 902868 R adenine specific DNA methylase Mod complement(901021..902868) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852536 YP_001651824.1 CDS APJL_0820 NC_010278.1 903123 904085 D hypothetical protein 903123..904085 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852535 YP_001651825.1 CDS APJL_0821 NC_010278.1 904231 904566 D hypothetical protein 904231..904566 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852534 YP_001651826.1 CDS mltA NC_010278.1 904633 905730 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(904633..905730) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852533 YP_001651827.1 CDS APJL_0825 NC_010278.1 907975 908388 R transthyretin-like periplasmic protein complement(907975..908388) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852527 YP_001651828.1 CDS purR1 NC_010278.1 908587 909597 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 908587..909597 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852526 YP_001651829.1 CDS APJL_0827 NC_010278.1 909620 910222 D DedA family integral membrane protein 909620..910222 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852525 YP_001651830.1 CDS gyrB NC_010278.1 910322 912754 R DNA gyrase subunit B complement(910322..912754) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852524 YP_001651831.1 CDS ubiA NC_010278.1 912967 913848 R catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase complement(912967..913848) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852523 YP_001651832.1 CDS glpR NC_010278.1 913848 914609 R glycerol-3-phosphate regulon repressor complement(913848..914609) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852521 YP_001651833.1 CDS purB NC_010278.1 914677 916044 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(914677..916044) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852518 YP_001651834.1 CDS APJL_0832 NC_010278.1 916101 916733 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(916101..916733) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852517 YP_001651835.1 CDS cydC NC_010278.1 916898 918565 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(916898..918565) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852516 YP_001651836.1 CDS cydD NC_010278.1 918576 920249 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(918576..920249) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852515 YP_001651837.1 CDS APJL_0835 NC_010278.1 920336 920503 R hypothetical protein complement(920336..920503) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852514 YP_001651838.1 CDS APJL_0836 NC_010278.1 920478 924437 R hypothetical protein complement(920478..924437) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852512 YP_001651839.1 CDS APJL_0837 NC_010278.1 924498 926324 R putative outer membrane protein complement(924498..926324) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852510 YP_001651840.1 CDS APJL_0838 NC_010278.1 926340 927020 R hypothetical protein complement(926340..927020) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852509 YP_001651841.1 CDS APJL_0839 NC_010278.1 927188 928387 R membrane-bound metallopeptidase complement(927188..928387) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852508 YP_001651842.1 CDS gpmA NC_010278.1 928566 929249 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 928566..929249 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852505 YP_001651843.1 CDS APJL_0841 NC_010278.1 929333 930064 R lysine efflux permease complement(929333..930064) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852503 YP_001651844.1 CDS udk NC_010278.1 930086 930739 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 930086..930739 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852501 YP_001651845.1 CDS dcd NC_010278.1 930748 931332 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 930748..931332 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852500 YP_001651846.1 CDS APJL_0844 NC_010278.1 931401 931955 R transcriptional regulator complement(931401..931955) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852499 YP_001651847.1 CDS acrA2 NC_010278.1 932096 933157 D membrane-fusion protein 932096..933157 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852498 YP_001651848.1 CDS ccmA1 NC_010278.1 933161 935902 D multidrug ABC transporter ATPase 933161..935902 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852496 YP_001651849.1 CDS APJL_0847 NC_010278.1 935904 937028 D multidrug ABC transporter permease 935904..937028 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852126 YP_001651850.1 CDS tolC NC_010278.1 937045 938439 D outer membrane protein 937045..938439 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852494 YP_001651851.1 CDS pntB NC_010278.1 938517 939965 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(938517..939965) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852493 YP_001651852.1 CDS pntA NC_010278.1 939976 941514 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(939976..941514) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852492 YP_001651853.1 CDS APJL_0851 NC_010278.1 941719 942447 D tRNA/rRNA methyltransferase 941719..942447 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852491 YP_001651854.1 CDS APJL_0852 NC_010278.1 942540 943631 R hypothetical protein complement(942540..943631) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852490 YP_001651855.1 CDS APJL_0853 NC_010278.1 943700 944791 R hypothetical protein complement(943700..944791) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852488 YP_001651856.1 CDS queF NC_010278.1 945004 945843 R catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(945004..945843) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852486 YP_001651857.1 CDS APJL_0855 NC_010278.1 945933 946481 R Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase complement(945933..946481) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852485 YP_001651858.1 CDS bcp NC_010278.1 946481 946951 R bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase complement(946481..946951) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852484 YP_001651859.1 CDS APJL_0857 NC_010278.1 947016 947225 R hypothetical protein complement(947016..947225) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852482 YP_001651860.1 CDS APJL_0858 NC_010278.1 947338 948495 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(947338..948495) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852481 YP_001651861.1 CDS APJL_0859 NC_010278.1 948758 950332 D putative ABC transporter periplasmic binding protein 948758..950332 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852480 YP_001651862.1 CDS APJL_0860 NC_010278.1 950431 951384 D ABC transporter permease 950431..951384 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852479 YP_001651863.1 CDS APJL_0861 NC_010278.1 951384 953357 D ABC transporter ATP-binding protein/permease 951384..953357 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852478 YP_001651864.1 CDS APJL_0862 NC_010278.1 953361 954167 D ABC transporter ATP-binding protein 953361..954167 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852476 YP_001651865.1 CDS sdhA NC_010278.1 954217 955815 D succinate dehydrogenase/fumarate reductase,flavoprotein subunit 954217..955815 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852475 YP_001651866.1 CDS APJL_0864 NC_010278.1 955877 957025 R methionine synthase II complement(955877..957025) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852473 YP_001651867.1 CDS metF NC_010278.1 957254 958135 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 957254..958135 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852472 YP_001651868.1 CDS hbpA1 NC_010278.1 958414 960006 R heme-binding protein A complement(958414..960006) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852470 YP_001651869.1 CDS sdaC NC_010278.1 960363 961592 D serine transporter 960363..961592 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852468 YP_001651870.1 CDS sdaA NC_010278.1 961688 963067 D L-serine dehydratase 961688..963067 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852467 YP_001651871.1 CDS mnmC NC_010278.1 963246 965261 R catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase complement(963246..965261) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852466 YP_001651872.1 CDS trpCF NC_010278.1 965465 966874 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(965465..966874) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852464 YP_001651873.1 CDS APJL_0871 NC_010278.1 967052 967717 D filamentation induced by cAMP protein Fic-like protein 967052..967717 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852462 YP_001651874.1 CDS APJL_0872 NC_010278.1 967725 968036 D hypothetical protein 967725..968036 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852461 YP_001651875.1 CDS APJL_0873 NC_010278.1 968037 968780 D catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 968037..968780 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852460 YP_001651876.1 CDS APJL_0874 NC_010278.1 968782 968946 D hypothetical protein 968782..968946 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852459 YP_001651877.1 CDS APJL_0875 NC_010278.1 968943 969395 D hypothetical protein 968943..969395 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852458 YP_001651878.1 CDS APJL_0876 NC_010278.1 969439 970278 R hypothetical protein complement(969439..970278) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852457 YP_001651879.1 CDS APJL_0877 NC_010278.1 970382 971755 D hypothetical protein 970382..971755 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852456 YP_001651880.1 CDS APJL_0878 NC_010278.1 971810 971935 D hypothetical protein 971810..971935 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852455 YP_001651881.1 CDS smpB NC_010278.1 971928 972368 D SsrA-binding protein, small major protein B 971928..972368 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852454 YP_001651882.1 CDS serS NC_010278.1 972486 973793 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 972486..973793 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852453 YP_001651883.1 CDS APJL_0881 NC_010278.1 973864 975132 R aminobenzoyl-glutamate utilization protein complement(973864..975132) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852452 YP_001651884.1 CDS APJL_0882 NC_010278.1 975226 976518 R C4-dicarboxylate transporter complement(975226..976518) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852450 YP_001651885.1 CDS pepE NC_010278.1 976529 977233 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(976529..977233) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852449 YP_001651886.1 CDS leuS NC_010278.1 977484 980069 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 977484..980069 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852448 YP_001651887.1 CDS rlpB NC_010278.1 980169 980663 D rare lipoprotein B 980169..980663 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852447 YP_001651888.1 CDS holA NC_010278.1 980772 981797 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 980772..981797 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852446 YP_001651889.1 CDS yacG NC_010278.1 981874 982062 R zinc-binding protein complement(981874..982062) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852445 YP_001651890.1 CDS coaE NC_010278.1 982044 982682 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(982044..982682) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852444 YP_001651891.1 CDS hopD NC_010278.1 982704 983342 R leader peptidase HopD complement(982704..983342) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852443 YP_001651892.1 CDS hofC NC_010278.1 983369 984571 R protein transport protein HofC-like protein complement(983369..984571) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852442 YP_001651893.1 CDS hofB NC_010278.1 984555 985949 R protein transport protein HofB-like protein, pili/fimbriae biogenesis protein complement(984555..985949) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852440 YP_001651894.1 CDS apfA NC_010278.1 985967 986413 R prepilin peptidase dependent protein D complement(985967..986413) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852439 YP_001651895.1 CDS radA NC_010278.1 986595 987974 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 986595..987974 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852438 YP_001651896.1 CDS APJL_0894 NC_010278.1 988018 988251 R hypothetical protein complement(988018..988251) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852437 YP_001651897.1 CDS folA NC_010278.1 988378 988866 R dihydrofolate reductase complement(988378..988866) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852436 YP_001651898.1 CDS proB NC_010278.1 988953 990044 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 988953..990044 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852435 YP_001651899.1 CDS APJL_0897 NC_010278.1 990057 990833 D permease 990057..990833 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852433 YP_001651900.1 CDS nth NC_010278.1 990834 991433 D endonuclease III 990834..991433 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852430 YP_001651901.1 CDS fadI NC_010278.1 991677 992981 D acetyl-CoA acetyltransferase 991677..992981 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852429 YP_001651902.1 CDS fadJ NC_010278.1 992991 995108 D fatty oxidation complex subunit alpha 992991..995108 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852428 YP_001651903.1 CDS APJL_0901 NC_010278.1 995199 996614 D hypothetical protein 995199..996614 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852427 YP_001651904.1 CDS APJL_0902 NC_010278.1 996697 997629 R permease complement(996697..997629) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852424 YP_001651905.1 CDS fdhD NC_010278.1 997631 998437 R formate dehydrogenase formation protein complement(997631..998437) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852423 YP_001651906.1 CDS bisC1 NC_010278.1 998857 999444 D formate dehydrogenase subunit alpha 998857..999444 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852422 YP_001651907.1 CDS bisC2 NC_010278.1 999493 1001916 D formate dehydrogenase subunit alpha 999493..1001916 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852421 YP_001651908.1 CDS hybA1 NC_010278.1 1001916 1002815 D formate dehydrogenase subunit beta 1001916..1002815 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852420 YP_001651909.1 CDS fdnI NC_010278.1 1002808 1003479 D formate dehydrogenase subunit gamma 1002808..1003479 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852419 YP_001651910.1 CDS fdhE NC_010278.1 1003589 1004506 D required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 1003589..1004506 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852418 YP_001651911.1 CDS folD NC_010278.1 1005109 1005966 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1005109..1005966 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852414 YP_001651912.1 CDS APJL_0910 NC_010278.1 1006111 1007649 D putative oxalate/formate antiporter 1006111..1007649 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852412 YP_001651913.1 CDS dapA NC_010278.1 1007747 1008634 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(1007747..1008634) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852411 YP_001651914.1 CDS lpxL NC_010278.1 1008793 1009734 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1008793..1009734) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852410 YP_001651915.1 CDS APJL_0913 NC_010278.1 1009899 1010213 D putative sigma 54 modulation protein 1009899..1010213 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852408 YP_001651916.1 CDS truA NC_010278.1 1010271 1011059 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1010271..1011059) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852407 YP_001651917.1 CDS folE NC_010278.1 1011138 1011794 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(1011138..1011794) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852406 YP_001651918.1 CDS kdkA NC_010278.1 1011895 1012599 D catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase 1011895..1012599 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852405 YP_001651919.1 CDS APJL_0917 NC_010278.1 1012679 1013017 R hypothetical protein complement(1012679..1013017) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852404 YP_001651920.1 CDS wbbJ NC_010278.1 1013076 1013651 R acetyltransferase complement(1013076..1013651) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852403 YP_001651921.1 CDS APJL_0919 NC_010278.1 1013735 1014877 R alpha/beta fold family hydrolase complement(1013735..1014877) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852712 YP_001651922.1 CDS APJL_0920 NC_010278.1 1015036 1015920 D putative transcriptional regulator 1015036..1015920 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852402 YP_001651923.1 CDS plpB NC_010278.1 1015973 1016791 R outer membrane lipoprotein 2 complement(1015973..1016791) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852400 YP_001651924.1 CDS hlpA NC_010278.1 1016905 1017726 R outer membrane lipoprotein complement(1016905..1017726) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852399 YP_001651925.1 CDS APJL_0923 NC_010278.1 1017752 1018429 R ABC transporter permease complement(1017752..1018429) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852398 YP_001651926.1 CDS metN NC_010278.1 1018419 1019453 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(1018419..1019453) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852397 YP_001651927.1 CDS cysS NC_010278.1 1019651 1021030 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(1019651..1021030) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852396 YP_001651928.1 CDS ppiB NC_010278.1 1021175 1021684 D peptidyl-prolyl cis-trans isomerase B 1021175..1021684 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852395 YP_001651929.1 CDS cca NC_010278.1 1021713 1022951 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 1021713..1022951 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852393 YP_001651930.1 CDS APJL_0928 NC_010278.1 1023096 1023605 D transposase and inactivated derivative 1023096..1023605 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852392 YP_001651931.1 CDS APJL_0929 NC_010278.1 1023617 1024429 D transposase 1023617..1024429 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852391 YP_001651932.1 CDS irp NC_010278.1 1024475 1026847 R iron-regulated outer membrane protein complement(1024475..1026847) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852390 YP_001651933.1 CDS APJL_0931 NC_010278.1 1027009 1028265 D hypothetical protein 1027009..1028265 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852389 YP_001651934.1 CDS APJL_0932 NC_010278.1 1028321 1029736 D hypothetical protein 1028321..1029736 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852388 YP_001651935.1 CDS APJL_0933 NC_010278.1 1030762 1030956 R hypothetical protein complement(1030762..1030956) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852387 YP_001651936.1 CDS fdx2 NC_010278.1 1030956 1031297 R ferredoxin complement(1030956..1031297) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852386 YP_001651937.1 CDS hscA NC_010278.1 1031418 1033271 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(1031418..1033271) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852384 YP_001651938.1 CDS APJL_0936 NC_010278.1 1033390 1034022 R hypothetical protein complement(1033390..1034022) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852383 YP_001651939.1 CDS APJL_0937 NC_010278.1 1034050 1034502 R hypothetical protein complement(1034050..1034502) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852381 YP_001651940.1 CDS hscB NC_010278.1 1034550 1035071 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(1034550..1035071) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852380 YP_001651941.1 CDS iscA NC_010278.1 1035081 1035404 R iron-binding protein complement(1035081..1035404) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852379 YP_001651942.1 CDS iscU NC_010278.1 1035546 1035929 R scaffold protein complement(1035546..1035929) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852378 YP_001651943.1 CDS iscS NC_010278.1 1036063 1037289 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(1036063..1037289) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852377 YP_001651944.1 CDS APJL_0942 NC_010278.1 1037344 1037796 R putative HTH-type transcriptional regulator complement(1037344..1037796) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852376 YP_001651945.1 CDS ompP1 NC_010278.1 1038286 1039677 D outer membrane protein P1 1038286..1039677 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852375 YP_001651946.1 CDS ogt NC_010278.1 1039763 1040326 D methylated-DNA--protein-cysteine S-methyltransferase 1039763..1040326 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852373 YP_001651947.1 CDS arcB NC_010278.1 1040346 1042196 R sensor histidine kinase complement(1040346..1042196) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852372 YP_001651948.1 CDS APJL_0946 NC_010278.1 1042302 1043165 R putative integral membrane protein complement(1042302..1043165) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852370 YP_001651949.1 CDS APJL_0947 NC_010278.1 1043281 1043823 R hypothetical protein complement(1043281..1043823) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852369 YP_001651950.1 CDS bioD NC_010278.1 1043813 1044457 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1043813..1044457) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852368 YP_001651951.1 CDS bioC NC_010278.1 1044457 1045227 R biotin synthesis protein complement(1044457..1045227) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852367 YP_001651952.1 CDS APJL_0950 NC_010278.1 1045215 1045874 R hypothetical protein complement(1045215..1045874) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852366 YP_001651953.1 CDS bioF NC_010278.1 1045884 1047047 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(1045884..1047047) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852365 YP_001651954.1 CDS bioA NC_010278.1 1047074 1048372 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(1047074..1048372) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852363 YP_001651955.1 CDS APJL_0953 NC_010278.1 1048463 1049407 D involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1048463..1049407 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852361 YP_001651956.1 CDS greA NC_010278.1 1049489 1049965 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1049489..1049965) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852360 YP_001651957.1 CDS dacB NC_010278.1 1050049 1051491 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1050049..1051491 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852359 YP_001651958.1 CDS APJL_0956 NC_010278.1 1051528 1051797 R acetyltransferase complement(1051528..1051797) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852357 YP_001651959.1 CDS APJL_0957 NC_010278.1 1052116 1053237 R hypothetical protein complement(1052116..1053237) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852354 YP_001651960.1 CDS APJL_0958 NC_010278.1 1053649 1053996 R hypothetical protein complement(1053649..1053996) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852353 YP_001651961.1 CDS APJL_0959 NC_010278.1 1054068 1055108 D hypothetical protein 1054068..1055108 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852352 YP_001651962.1 CDS APJL_0960 NC_010278.1 1055147 1056181 R hypothetical protein complement(1055147..1056181) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852351 YP_001651963.1 CDS APJL_0961 NC_010278.1 1056174 1056737 R Zn peptidase complement(1056174..1056737) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852349 YP_001651964.1 CDS APJL_0962 NC_010278.1 1056891 1057199 R hypothetical protein complement(1056891..1057199) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852348 YP_001651965.1 CDS APJL_0963 NC_010278.1 1057262 1058347 D putative transposase 1057262..1058347 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852347 YP_001651966.1 CDS APJL_0964 NC_010278.1 1058347 1058781 D DNA repair ATPase 1058347..1058781 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852346 YP_001651967.1 CDS APJL_0965 NC_010278.1 1058782 1059171 R hypothetical protein complement(1058782..1059171) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852345 YP_001651968.1 CDS apxIIB NC_010278.1 1059213 1059785 R leukotoxin translocation ATP-binding protein complement(1059213..1059785) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852344 YP_001651969.1 CDS apxIIA NC_010278.1 1059850 1062720 R hemolysin A complement(1059850..1062720) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852343 YP_001651970.1 CDS apxIIC NC_010278.1 1062759 1063241 R hemolysin-activating lysine-acyltransferase HlyC complement(1062759..1063241) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852342 YP_001651971.1 CDS APJL_0969 NC_010278.1 1063418 1065286 R hypothetical protein complement(1063418..1065286) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852340 YP_001651972.1 CDS APJL_0970 NC_010278.1 1065316 1065807 R putative metalloprotease complement(1065316..1065807) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852338 YP_001651973.1 CDS purH NC_010278.1 1066230 1067819 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1066230..1067819 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852336 YP_001651974.1 CDS APJL_0972 NC_010278.1 1067928 1068968 D hypothetical protein 1067928..1068968 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852335 YP_001651975.1 CDS APJL_0973 NC_010278.1 1069217 1069573 R hypothetical protein complement(1069217..1069573) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852334 YP_001651976.1 CDS APJL_0974 NC_010278.1 1069587 1069892 R hypothetical protein complement(1069587..1069892) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852333 YP_001651977.1 CDS APJL_0975 NC_010278.1 1069984 1070148 R hypothetical protein complement(1069984..1070148) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852331 YP_001651978.1 CDS APJL_0976 NC_010278.1 1070293 1070625 R hypothetical protein complement(1070293..1070625) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852330 YP_001651979.1 CDS APJL_0977 NC_010278.1 1070622 1070834 R heme utilization or adhesion protein complement(1070622..1070834) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852329 YP_001651980.1 CDS APJL_0978 NC_010278.1 1071004 1071303 R hypothetical protein complement(1071004..1071303) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852327 YP_001651981.1 CDS APJL_0979 NC_010278.1 1071300 1079093 R heme utilization or adhesion protein complement(1071300..1079093) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852326 YP_001651982.1 CDS APJL_0980 NC_010278.1 1079141 1080913 R hemolysin activation/secretion protein complement(1079141..1080913) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852324 YP_001651983.1 CDS imp NC_010278.1 1081096 1083432 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(1081096..1083432) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852323 YP_001651984.1 CDS hemN NC_010278.1 1083489 1084856 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1083489..1084856) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852322 YP_001651985.1 CDS APJL_0983 NC_010278.1 1084886 1085353 R putative coproporphyrinogen III oxidase complement(1084886..1085353) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852321 YP_001651986.1 CDS APJL_0984 NC_010278.1 1085369 1085947 R hypothetical protein complement(1085369..1085947) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852320 YP_001651987.1 CDS APJL_0985 NC_010278.1 1086096 1087754 R hypothetical protein complement(1086096..1087754) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852318 YP_001651988.1 CDS gltS NC_010278.1 1088017 1089234 D sodium/glutamate symporter 1088017..1089234 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852315 YP_001651989.1 CDS APJL_0987 NC_010278.1 1089304 1089681 R hypothetical protein complement(1089304..1089681) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852314 YP_001651990.1 CDS glnE NC_010278.1 1089778 1092657 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(1089778..1092657) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852313 YP_001651991.1 CDS APJL_0989 NC_010278.1 1092732 1093013 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(1092732..1093013) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852312 YP_001651992.1 CDS APJL_0990 NC_010278.1 1093024 1093515 R putative acyl CoA thioester hydrolase complement(1093024..1093515) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852311 YP_001651993.1 CDS ispZ NC_010278.1 1093502 1094053 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1093502..1094053) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852308 YP_001651994.1 CDS APJL_0992 NC_010278.1 1094055 1094792 R hypothetical protein complement(1094055..1094792) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852307 YP_001651995.1 CDS APJL_0993 NC_010278.1 1094951 1095385 D membrane protein 1094951..1095385 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852306 YP_001651996.1 CDS APJL_0994 NC_010278.1 1095398 1095556 D hypothetical protein 1095398..1095556 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852305 YP_001651997.1 CDS APJL_0995 NC_010278.1 1095553 1096509 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1095553..1096509 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852304 YP_001651998.1 CDS APJL_0996 NC_010278.1 1096716 1098092 D permease 1096716..1098092 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852303 YP_001651999.1 CDS xthA NC_010278.1 1098144 1098986 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1098144..1098986 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852302 YP_001652000.1 CDS lysR1 NC_010278.1 1099050 1099934 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(1099050..1099934) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852301 YP_001652001.1 CDS APJL_0999 NC_010278.1 1099935 1100975 R putative D-glycero-D-manno-heptosyltransferase complement(1099935..1100975) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852300 YP_001652002.1 CDS lbgA NC_010278.1 1100977 1101660 R lipooligosaccharide galactosyltransferase I complement(1100977..1101660) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852299 YP_001652003.1 CDS APJL_1001 NC_010278.1 1101769 1102830 D hypothetical protein 1101769..1102830 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852298 YP_001652004.1 CDS rpmE NC_010278.1 1102892 1103104 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(1102892..1103104) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852297 YP_001652005.1 CDS tktA NC_010278.1 1103486 1105492 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1103486..1105492 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852295 YP_001652006.1 CDS htpG NC_010278.1 1105626 1107503 R molecular chaperone; heat shock protein 90 complement(1105626..1107503) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852294 YP_001652007.1 CDS katA NC_010278.1 1107731 1109257 D catalase 1107731..1109257 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852292 YP_001652008.1 CDS APJL_1006 NC_010278.1 1109424 1109603 D transposase and inactivated derivative 1109424..1109603 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852291 YP_001652009.1 CDS APJL_1007 NC_010278.1 1109623 1109961 D transposase 1109623..1109961 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852290 YP_001652010.1 CDS APJL_1008 NC_010278.1 1110074 1111153 D phosphohydrolase 1110074..1111153 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852289 YP_001652011.1 CDS nrdA NC_010278.1 1111367 1113637 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1111367..1113637 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852288 YP_001652012.1 CDS nrdB NC_010278.1 1113934 1115064 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1113934..1115064 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852287 YP_001652013.1 CDS galT NC_010278.1 1115326 1116375 D catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 1115326..1116375 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852286 YP_001652014.1 CDS galK NC_010278.1 1116403 1117557 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1116403..1117557 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852285 YP_001652015.1 CDS galM NC_010278.1 1117615 1118583 D aldose 1-epimerase 1117615..1118583 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852283 YP_001652016.1 CDS lacZ NC_010278.1 1118608 1121628 D beta-galactosidase/beta-glucuronidase 1118608..1121628 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852282 YP_001652017.1 CDS APJL_1017 NC_010278.1 1126340 1126810 R hypothetical protein complement(1126340..1126810) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852279 YP_001652018.1 CDS mrp NC_010278.1 1127007 1128104 R putative ATPase complement(1127007..1128104) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852278 YP_001652019.1 CDS APJL_1019 NC_010278.1 1128108 1129658 R putative oligopeptide transporter,periplasmic-binding protein complement(1128108..1129658) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852277 YP_001652020.1 CDS APJL_1020 NC_010278.1 1129673 1130326 R hypothetical protein complement(1129673..1130326) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852276 YP_001652021.1 CDS ppiD NC_010278.1 1130448 1132325 R peptidyl-prolyl cis-trans isomerase D complement(1130448..1132325) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852275 YP_001652022.1 CDS nhaP NC_010278.1 1132554 1133867 D Na+/H+ antiporter 1132554..1133867 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852274 YP_001652023.1 CDS rpsO NC_010278.1 1133989 1134258 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1133989..1134258 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852273 YP_001652024.1 CDS APJL_1024 NC_010278.1 1134336 1135205 D inner membrane protein 1134336..1135205 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852272 YP_001652025.1 CDS hemY NC_010278.1 1135263 1136513 R HemY protein complement(1135263..1136513) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852270 YP_001652026.1 CDS hemX NC_010278.1 1136525 1137865 R putative uroporphyrinogen IIIC-methyltransferase complement(1136525..1137865) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852269 YP_001652027.1 CDS hemD NC_010278.1 1137875 1138588 R uroporphyrinogen-III synthase complement(1137875..1138588) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852268 YP_001652028.1 CDS hemC NC_010278.1 1138648 1139592 R porphobilinogen deaminase complement(1138648..1139592) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852267 YP_001652029.1 CDS adh2 NC_010278.1 1139846 1142461 D bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1139846..1142461 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852266 YP_001652030.1 CDS groEL NC_010278.1 1142635 1144278 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(1142635..1144278) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852265 YP_001652031.1 CDS groES NC_010278.1 1144338 1144628 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(1144338..1144628) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852263 YP_001652032.1 CDS deoD NC_010278.1 1144840 1145562 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(1144840..1145562) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852262 YP_001652033.1 CDS deoC NC_010278.1 1145621 1146397 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(1145621..1146397) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852260 YP_001652034.1 CDS APJL_1034 NC_010278.1 1146534 1147802 R nucleoside permease complement(1146534..1147802) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852259 YP_001652035.1 CDS APJL_1035 NC_010278.1 1148016 1148660 D hypothetical protein 1148016..1148660 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852258 YP_001652036.1 CDS eda NC_010278.1 1148712 1149353 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(1148712..1149353) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852256 YP_001652037.1 CDS rbsK1 NC_010278.1 1149368 1150282 R sugar kinase complement(1149368..1150282) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852255 YP_001652038.1 CDS uxaC NC_010278.1 1150325 1150915 R glucuronate isomerase complement(1150325..1150915) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852254 YP_001652039.1 CDS APJL_1039 NC_010278.1 1151217 1152695 D alpha-glucosidase 1151217..1152695 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852252 YP_001652040.1 CDS APJL_1040 NC_010278.1 1152699 1152935 D transcriptional regulator 1152699..1152935 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852251 YP_001652041.1 CDS APJL_1041 NC_010278.1 1152910 1153338 D hypothetical protein 1152910..1153338 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852250 YP_001652042.1 CDS APJL_1042 NC_010278.1 1153582 1154088 D peptide methionine sulfoxide reductase 1153582..1154088 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852249 YP_001652043.1 CDS lsgF NC_010278.1 1154123 1154923 R putative UDP-galactose--lipooligosaccharide galactosyltransferase complement(1154123..1154923) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852247 YP_001652044.1 CDS lsgE NC_010278.1 1154923 1155804 R putative lipooligosaccharide galactosyltransferase complement(1154923..1155804) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852246 YP_001652045.1 CDS APJL_1045 NC_010278.1 1155797 1156996 R hypothetical protein complement(1155797..1156996) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852245 YP_001652046.1 CDS lsgD NC_010278.1 1156997 1157767 R LPS biosynthesis glycosyltransferase complement(1156997..1157767) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852244 YP_001652047.1 CDS APJL_1047 NC_010278.1 1157764 1158897 R hypothetical protein complement(1157764..1158897) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852242 YP_001652048.1 CDS APJL_1048 NC_010278.1 1158950 1159915 R exopolysaccharide biosynthesis protein complement(1158950..1159915) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852241 YP_001652049.1 CDS APJL_1049 NC_010278.1 1160071 1160811 D hypothetical protein 1160071..1160811 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852240 YP_001652050.1 CDS priA NC_010278.1 1160891 1163131 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1160891..1163131) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852239 YP_001652051.1 CDS pheA NC_010278.1 1163192 1164349 R prephenate dehydratase / chorismate mutase complement(1163192..1164349) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852238 YP_001652052.1 CDS prlC NC_010278.1 1164472 1166505 R oligopeptidase A complement(1164472..1166505) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852237 YP_001652053.1 CDS pflA NC_010278.1 1166646 1167383 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1166646..1167383) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852236 YP_001652054.1 CDS pflB NC_010278.1 1167511 1169823 R formate acetyltransferase complement(1167511..1169823) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852235 YP_001652055.1 CDS focA NC_010278.1 1169916 1170740 R formate transporter complement(1169916..1170740) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852234 YP_001652056.1 CDS APJL_1056 NC_010278.1 1170946 1171428 D hypothetical protein 1170946..1171428 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852233 YP_001652057.1 CDS htpX NC_010278.1 1171488 1172357 R putative metalloprotease; heat shock protein HtpX complement(1171488..1172357) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852232 YP_001652058.1 CDS dinP NC_010278.1 1172445 1173515 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(1172445..1173515) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852231 YP_001652059.1 CDS APJL_1059 NC_010278.1 1173622 1174530 D hypothetical protein 1173622..1174530 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852230 YP_001652060.1 CDS menF NC_010278.1 1174569 1175849 R menaquinone-specific isochorismate synthase complement(1174569..1175849) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852229 YP_001652061.1 CDS APJL_1061 NC_010278.1 1176013 1177230 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1176013..1177230 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852228 YP_001652062.1 CDS APJL_1062 NC_010278.1 1177274 1178167 D permease 1177274..1178167 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852226 YP_001652063.1 CDS rarD NC_010278.1 1178168 1179034 D permease 1178168..1179034 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852224 YP_001652064.1 CDS APJL_1064 NC_010278.1 1179031 1179648 D putative threonine efflux protein 1179031..1179648 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852223 YP_001652065.1 CDS hgbA NC_010278.1 1179729 1182575 R hemoglobin and hemoglobin-haptoglobin-binding protein 4 complement(1179729..1182575) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852221 YP_001652066.1 CDS hugZ NC_010278.1 1182635 1183156 R putative heme iron utilization protein complement(1182635..1183156) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852220 YP_001652067.1 CDS nrfG NC_010278.1 1183360 1184106 R formate-dependent nitrite reductase complex NrfG subunit complement(1183360..1184106) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852218 YP_001652068.1 CDS nrfF NC_010278.1 1184084 1184518 R formate-dependent nitrite reductase complex subunit NrfF complement(1184084..1184518) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852217 YP_001652069.1 CDS dsbE2 NC_010278.1 1184518 1185051 R thiol:disulfide interchange protein complement(1184518..1185051) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852216 YP_001652070.1 CDS nfrE NC_010278.1 1185053 1186969 R cytochrome c-type biogenesis protein complement(1185053..1186969) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852215 YP_001652071.1 CDS kefB NC_010278.1 1187140 1189005 R glutathione-regulated potassium-efflux system protein complement(1187140..1189005) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852214 YP_001652072.1 CDS cyaA NC_010278.1 1189094 1191622 R catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase complement(1189094..1191622) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852213 YP_001652073.1 CDS fabB NC_010278.1 1191877 1193097 D FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1191877..1193097 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852212 YP_001652074.1 CDS APJL_1074 NC_010278.1 1193289 1193798 D transposase and inactivated derivative 1193289..1193798 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852211 YP_001652075.1 CDS APJL_1075 NC_010278.1 1193804 1194622 D transposase 1193804..1194622 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852209 YP_001652076.1 CDS APJL_1076 NC_010278.1 1194769 1195116 D hypothetical protein 1194769..1195116 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852208 YP_001652077.1 CDS APJL_1077 NC_010278.1 1195172 1195768 D hypothetical protein 1195172..1195768 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852207 YP_001652078.1 CDS APJL_1078 NC_010278.1 1195809 1196183 D hypothetical protein 1195809..1196183 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852206 YP_001652079.1 CDS ygiX NC_010278.1 1196221 1196937 D transcriptional regulatory protein 1196221..1196937 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852205 YP_001652080.1 CDS ygiY NC_010278.1 1196930 1198306 D sensor protein 1196930..1198306 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852204 YP_001652081.1 CDS APJL_1081 NC_010278.1 1198354 1198914 R hypothetical protein complement(1198354..1198914) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852201 YP_001652082.1 CDS yajC NC_010278.1 1199108 1199404 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1199108..1199404 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852200 YP_001652083.1 CDS secD NC_010278.1 1199464 1201278 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1199464..1201278 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852199 YP_001652084.1 CDS secF NC_010278.1 1201289 1202263 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1201289..1202263 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852197 YP_001652085.1 CDS ftnA NC_010278.1 1202413 1202919 D ferritin-like protein 1 1202413..1202919 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852196 YP_001652086.1 CDS ftnB NC_010278.1 1202919 1203416 D ferritin-like protein 2 1202919..1203416 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852195 YP_001652087.1 CDS APJL_1087 NC_010278.1 1203656 1204957 D putative xanthine/uracil permease 1203656..1204957 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852194 YP_001652088.1 CDS APJL_1088 NC_010278.1 1205012 1205602 R putative MAF protein complement(1205012..1205602) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852193 YP_001652089.1 CDS APJL_1089 NC_010278.1 1205758 1206300 D putative macrophage infectivity potentiator-related protein 1205758..1206300 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852192 YP_001652090.1 CDS thiI NC_010278.1 1206396 1207793 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(1206396..1207793) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852190 YP_001652091.1 CDS purA NC_010278.1 1208031 1209329 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1208031..1209329) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852188 YP_001652092.1 CDS hflC NC_010278.1 1209516 1210403 R HflC protein complement(1209516..1210403) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852187 YP_001652093.1 CDS hflK NC_010278.1 1210406 1211596 R HflK protein complement(1210406..1211596) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852186 YP_001652094.1 CDS trxA NC_010278.1 1211774 1212091 R thioredoxin complement(1211774..1212091) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852184 YP_001652095.1 CDS APJL_1095 NC_010278.1 1212227 1213519 R putative xanthine permease complement(1212227..1213519) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852182 YP_001652096.1 CDS metK NC_010278.1 1213681 1214832 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1213681..1214832) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852181 YP_001652097.1 CDS APJL_1097 NC_010278.1 1215052 1215945 D homocysteine/selenocysteine methylase 1215052..1215945 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852180 YP_001652098.1 CDS arcD1 NC_010278.1 1216036 1217451 D putative arginine/ornithine antiporter 1216036..1217451 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852179 YP_001652099.1 CDS arcD2 NC_010278.1 1217547 1218953 D putative arginine/ornithine antiporter protein 1217547..1218953 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852178 YP_001652100.1 CDS APJL_1100 NC_010278.1 1218962 1219741 D hypothetical protein 1218962..1219741 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852177 YP_001652101.1 CDS argE NC_010278.1 1219756 1220898 D catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 1219756..1220898 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852176 YP_001652102.1 CDS ompW NC_010278.1 1220979 1221626 R outer membrane protein ompW complement(1220979..1221626) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852175 YP_001652103.1 CDS clpB NC_010278.1 1221887 1224460 D ATP-dependent Clp protease subunit B 1221887..1224460 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852174 YP_001652104.1 CDS acr3 NC_010278.1 1224517 1225518 R arsenite efflux pump ACR3 complement(1224517..1225518) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852173 YP_001652105.1 CDS arsC NC_010278.1 1225530 1225934 R arsenate reductase complement(1225530..1225934) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852172 YP_001652106.1 CDS APJL_1106 NC_010278.1 1225994 1226308 R putative transcriptional regulator complement(1225994..1226308) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852171 YP_001652107.1 CDS aspA NC_010278.1 1226436 1227863 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(1226436..1227863) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852169 YP_001652108.1 CDS APJL_1108 NC_010278.1 1228004 1228285 R hypothetical protein complement(1228004..1228285) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852168 YP_001652109.1 CDS purM NC_010278.1 1228359 1229396 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(1228359..1229396) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852167 YP_001652110.1 CDS dspB NC_010278.1 1229611 1230744 D N-acetyl-beta-hexosaminidase 1229611..1230744 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852166 YP_001652111.1 CDS queC NC_010278.1 1230892 1231560 D queuosine biosynthesis protein QueC 1230892..1231560 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852165 YP_001652112.1 CDS APJL_1112 NC_010278.1 1231553 1231975 D 6-pyruvoyl-tetrahydropterin synthase 1231553..1231975 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852164 YP_001652113.1 CDS APJL_1113 NC_010278.1 1232068 1232700 D organic radical activating enzyme 1232068..1232700 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852163 YP_001652114.1 CDS APJL_1114 NC_010278.1 1232841 1233398 R hypothetical protein complement(1232841..1233398) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852653 YP_001652115.1 CDS APJL_1115 NC_010278.1 1233454 1233723 R hypothetical protein complement(1233454..1233723) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852742 YP_001652116.1 CDS pepA NC_010278.1 1234067 1235566 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(1234067..1235566) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852341 YP_001652117.1 CDS APJL_1117 NC_010278.1 1235934 1236749 D hypothetical protein 1235934..1236749 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852463 YP_001652118.1 CDS APJL_1118 NC_010278.1 1237047 1238051 D permease 1237047..1238051 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852356 YP_001652119.1 CDS APJL_1119 NC_010278.1 1238052 1239134 D permease 1238052..1239134 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852451 YP_001652120.1 CDS dnaE NC_010278.1 1239341 1242817 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1239341..1242817 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852502 YP_001652121.1 CDS APJL_1121 NC_010278.1 1243573 1243668 R hypothetical protein complement(1243573..1243668) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852511 YP_001652122.1 CDS purT1 NC_010278.1 1243682 1244068 R phosphoribosylglycinamide formyltransferase 2 complement(1243682..1244068) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852633 YP_001652123.1 CDS APJL_1123 NC_010278.1 1244945 1246135 R hypothetical protein complement(1244945..1246135) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852156 YP_001652124.1 CDS APJL_1124 NC_010278.1 1246113 1246304 R hypothetical protein complement(1246113..1246304) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851719 YP_001652125.1 CDS purT NC_010278.1 1247008 1248189 R non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 complement(1247008..1248189) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852142 YP_001652126.1 CDS plsB NC_010278.1 1248312 1250786 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(1248312..1250786) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852507 YP_001652127.1 CDS lexA NC_010278.1 1250943 1251575 D Represses a number of genes involved in the response to DNA damage; LexA repressor 1250943..1251575 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852158 YP_001652128.1 CDS mutH NC_010278.1 1251635 1252315 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 1251635..1252315 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852730 YP_001652129.1 CDS APJL_1129 NC_010278.1 1252401 1253132 D hypothetical protein 1252401..1253132 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852170 YP_001652130.1 CDS nagZ NC_010278.1 1253247 1254284 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1253247..1254284 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852189 YP_001652131.1 CDS rumB NC_010278.1 1254365 1255540 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1254365..1255540 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852339 YP_001652132.1 CDS eno NC_010278.1 1255747 1257057 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1255747..1257057 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852811 YP_001652133.1 CDS APJL_1133 NC_010278.1 1257082 1257762 D hypothetical protein 1257082..1257762 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852804 YP_001652134.1 CDS APJL_1134 NC_010278.1 1257776 1258186 D hypothetical protein 1257776..1258186 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852132 YP_001652135.1 CDS recQ NC_010278.1 1258245 1260053 R ATP-dependent DNA helicase complement(1258245..1260053) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852131 YP_001652136.1 CDS cyaY NC_010278.1 1260138 1260443 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(1260138..1260443) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852803 YP_001652137.1 CDS lpsA1 NC_010278.1 1260452 1260922 R lipooligosaccharide biosynthesis protein complement(1260452..1260922) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851381 YP_001652138.1 CDS lpsA2 NC_010278.1 1260926 1261228 R lipooligosaccharide biosynthesis protein complement(1260926..1261228) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852787 YP_001652139.1 CDS gcp NC_010278.1 1261269 1262312 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(1261269..1262312) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852821 YP_001652140.1 CDS APJL_1140 NC_010278.1 1262404 1263180 R putative lipoprotein complement(1262404..1263180) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852840 YP_001652141.1 CDS rluD NC_010278.1 1263333 1264310 D responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 1263333..1264310 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851795 YP_001652142.1 CDS APJL_1142 NC_010278.1 1264354 1265067 R hypothetical protein complement(1264354..1265067) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851179 YP_001652143.1 CDS pfkA NC_010278.1 1265128 1266102 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(1265128..1266102) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851972 YP_001652144.1 CDS nifS NC_010278.1 1266212 1267414 R cysteine desulfurase complement(1266212..1267414) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851561 YP_001652145.1 CDS APJL_1145 NC_010278.1 1267414 1268112 R putative endonuclease complement(1267414..1268112) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851650 YP_001652146.1 CDS APJL_1146 NC_010278.1 1268178 1269545 R Na+/alanine symporter complement(1268178..1269545) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851041 YP_001652147.1 CDS APJL_1147 NC_010278.1 1270012 1271064 R hypothetical protein complement(1270012..1271064) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851346 YP_001652148.1 CDS cytB562 NC_010278.1 1271158 1271532 R soluble cytochrome b562 complement(1271158..1271532) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850992 YP_001652149.1 CDS APJL_1149 NC_010278.1 1271681 1273078 D putative protease 1271681..1273078 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851779 YP_001652150.1 CDS APJL_1150 NC_010278.1 1273222 1274571 D hypothetical protein 1273222..1274571 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851560 YP_001652151.1 CDS waaA NC_010278.1 1274571 1275851 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 1274571..1275851 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851369 YP_001652152.1 CDS coaD NC_010278.1 1275853 1276329 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1275853..1276329 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850886 YP_001652153.1 CDS APJL_1153 NC_010278.1 1276332 1276886 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1276332..1276886 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850714 YP_001652154.1 CDS APJL_1154 NC_010278.1 1276894 1277385 D ATP-binding protein 1276894..1277385 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851382 YP_001652155.1 CDS amiB NC_010278.1 1277409 1278554 D N-acetylmuramoyl-L-alanine amidase 1277409..1278554 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851511 YP_001652156.1 CDS pgi NC_010278.1 1278633 1280273 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1278633..1280273) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850864 YP_001652157.1 CDS APJL_1157 NC_010278.1 1280310 1280561 R hypothetical protein complement(1280310..1280561) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851638 YP_001652158.1 CDS aroE NC_010278.1 1281245 1282069 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1281245..1282069) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851826 YP_001652159.1 CDS APJL_1159 NC_010278.1 1282076 1282630 R hypothetical protein complement(1282076..1282630) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850968 YP_001652160.1 CDS APJL_1160 NC_010278.1 1282623 1283156 R DNA topoisomerase I-related protein complement(1282623..1283156) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852529 YP_001652161.1 CDS APJL_1161 NC_010278.1 1283153 1283473 R hypothetical protein complement(1283153..1283473) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851683 YP_001652162.1 CDS recX NC_010278.1 1283524 1283925 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(1283524..1283925) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851668 YP_001652163.1 CDS recA NC_010278.1 1283979 1285109 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1283979..1285109) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850771 YP_001652164.1 CDS APJL_1164 NC_010278.1 1285223 1285828 R hypothetical protein complement(1285223..1285828) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851540 YP_001652165.1 CDS pabB NC_010278.1 1285806 1286774 R catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I complement(1285806..1286774) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851533 YP_001652166.1 CDS rmuC NC_010278.1 1286909 1288543 D DNA recombination protein RmuC-like protein 1286909..1288543 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851320 YP_001652167.1 CDS trpG NC_010278.1 1288527 1289126 D catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; putative anthranilate synthase component II 1288527..1289126 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850931 YP_001652168.1 CDS APJL_1168 NC_010278.1 1289198 1289647 D hypothetical protein 1289198..1289647 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851106 YP_001652169.1 CDS aspS NC_010278.1 1289819 1291594 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1289819..1291594 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850872 YP_001652170.1 CDS ntpA NC_010278.1 1291694 1292098 D converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1291694..1292098 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851338 YP_001652171.1 CDS APJL_1171 NC_010278.1 1292122 1292862 D hypothetical protein 1292122..1292862 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851783 YP_001652172.1 CDS APJL_1172 NC_010278.1 1292995 1293519 D hypothetical protein 1292995..1293519 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851703 YP_001652173.1 CDS ruvC NC_010278.1 1293579 1294181 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1293579..1294181 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851627 YP_001652174.1 CDS APJL_1174 NC_010278.1 1294221 1295735 R putative zinc protease complement(1294221..1295735) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851407 YP_001652175.1 CDS metE NC_010278.1 1295893 1298166 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase complement(1295893..1298166) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851746 YP_001652176.1 CDS citT NC_010278.1 1298397 1299719 R di- and tricarboxylate transporter complement(1298397..1299719) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851365 YP_001652177.1 CDS lysR2 NC_010278.1 1300082 1301011 D transcriptional regulator 1300082..1301011 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850888 YP_001652178.1 CDS APJL_1178 NC_010278.1 1301089 1302225 R hypothetical protein complement(1301089..1302225) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851648 YP_001652179.1 CDS APJL_1179 NC_010278.1 1302358 1303407 R pseudouridine synthase complement(1302358..1303407) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851249 YP_001652180.1 CDS APJL_1180 NC_010278.1 1303479 1304096 R putative translation factor complement(1303479..1304096) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851619 YP_001652181.1 CDS APJL_1181 NC_010278.1 1304295 1304525 R hypothetical protein complement(1304295..1304525) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851423 YP_001652182.1 CDS APJL_1182 NC_010278.1 1304641 1305537 R iron-dependent peroxidase complement(1304641..1305537) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851111 YP_001652183.1 CDS trpE NC_010278.1 1305709 1307259 D with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1305709..1307259 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851773 YP_001652184.1 CDS pabA NC_010278.1 1307273 1307860 D TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1307273..1307860 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851906 YP_001652185.1 CDS trpD NC_010278.1 1307917 1308921 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1307917..1308921 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851919 YP_001652186.1 CDS APJL_1186 NC_010278.1 1308964 1309719 D SAM-dependent methyltransferase 1308964..1309719 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850744 YP_001652187.1 CDS APJL_1187 NC_010278.1 1309746 1310831 R hypothetical protein complement(1309746..1310831) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850892 YP_001652188.1 CDS APJL_1188 NC_010278.1 1311027 1311242 D hypothetical protein 1311027..1311242 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850723 YP_001652189.1 CDS rplI NC_010278.1 1311331 1311780 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(1311331..1311780) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850772 YP_001652190.1 CDS rpsR NC_010278.1 1311798 1312025 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1311798..1312025) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851956 YP_001652191.1 CDS priB NC_010278.1 1312000 1312374 R binds single-stranded DNA at the primosome assembly site; primosomal replication protein N complement(1312000..1312374) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851857 YP_001652192.1 CDS rpsF NC_010278.1 1312349 1312723 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1312349..1312723) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851728 YP_001652193.1 CDS purD NC_010278.1 1313012 1314298 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1313012..1314298 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851985 YP_001652194.1 CDS APJL_1194 NC_010278.1 1314390 1315082 R nicotinamide mononucleotide transporter complement(1314390..1315082) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851713 YP_001652195.1 CDS APJL_1195 NC_010278.1 1315210 1315833 R hypothetical protein complement(1315210..1315833) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851483 YP_001652196.1 CDS hisS NC_010278.1 1315849 1317090 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1315849..1317090) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851921 YP_001652197.1 CDS APJL_1197 NC_010278.1 1317141 1317233 R hypothetical protein complement(1317141..1317233) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850757 YP_001652198.1 CDS ispG NC_010278.1 1317248 1318360 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(1317248..1318360) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850805 YP_001652199.1 CDS APJL_1199 NC_010278.1 1318370 1319338 R hypothetical protein complement(1318370..1319338) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851738 YP_001652200.1 CDS APJL_1200 NC_010278.1 1319618 1321174 D integral membrane sulfate transporter 1319618..1321174 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850770 YP_001652201.1 CDS argH NC_010278.1 1321485 1322861 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(1321485..1322861) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850840 YP_001652202.1 CDS APJL_1202 NC_010278.1 1323142 1324182 R putative oxidoreductase complement(1323142..1324182) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851644 YP_001652203.1 CDS kefBC NC_010278.1 1324433 1326238 D glutathione-regulated potassium-efflux system protein 1324433..1326238 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850779 YP_001652204.1 CDS APJL_1204 NC_010278.1 1326591 1326815 D hypothetical protein 1326591..1326815 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851273 YP_001652205.1 CDS APJL_1205 NC_010278.1 1326832 1327929 D hypothetical protein 1326832..1327929 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851784 YP_001652206.1 CDS APJL_1206 NC_010278.1 1328034 1328927 R putative HTH-type transcriptional regulator complement(1328034..1328927) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851518 YP_001652207.1 CDS APJL_1207 NC_010278.1 1329051 1329503 D hypothetical protein 1329051..1329503 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851017 YP_001652208.1 CDS APJL_1208 NC_010278.1 1329626 1330261 R hypothetical protein complement(1329626..1330261) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851281 YP_001652209.1 CDS yqhC NC_010278.1 1330598 1331449 D putative HTH-type transcriptional regulator 1330598..1331449 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851155 YP_001652210.1 CDS nahR NC_010278.1 1331508 1332407 R HTH-type transcriptional activator complement(1331508..1332407) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851112 YP_001652211.1 CDS APJL_1211 NC_010278.1 1332628 1333584 D NADPH dehydrogenase 1332628..1333584 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851610 YP_001652212.1 CDS APJL_1212 NC_010278.1 1333654 1334703 D putative oxidoreductase 1333654..1334703 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851725 YP_001652213.1 CDS APJL_1213 NC_010278.1 1334762 1335631 R 3-hydroxyisobutyrate dehydrogenase complement(1334762..1335631) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851076 YP_001652214.1 CDS nfnB NC_010278.1 1335942 1336595 D putative NAD(P)H nitroreductase 1335942..1336595 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851301 YP_001652215.1 CDS marC NC_010278.1 1336758 1337375 D MarC family integral membrane protein 1336758..1337375 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850827 YP_001652216.1 CDS APJL_1216 NC_010278.1 1337406 1338017 D hypothetical protein 1337406..1338017 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850834 YP_001652217.1 CDS APJL_1217 NC_010278.1 1338091 1338948 R putative esterase complement(1338091..1338948) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851609 YP_001652218.1 CDS APJL_1218 NC_010278.1 1338963 1339757 R putative GST-like protein complement(1338963..1339757) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851957 YP_001652219.1 CDS pilT NC_010278.1 1339933 1340352 R PilT domain-containing protein complement(1339933..1340352) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851419 YP_001652220.1 CDS APJL_1220 NC_010278.1 1340362 1340619 R antitoxin of toxin-antitoxin stability system complement(1340362..1340619) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851178 YP_001652221.1 CDS adh1 NC_010278.1 1340769 1341887 R putative alcohol dehydrogenase class III complement(1340769..1341887) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850887 YP_001652222.1 CDS APJL_1222 NC_010278.1 1342042 1344069 R choline-glycine betaine transporter complement(1342042..1344069) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851996 YP_001652223.1 CDS APJL_1223 NC_010278.1 1344366 1345076 D hypothetical protein 1344366..1345076 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851729 YP_001652224.1 CDS APJL_1224 NC_010278.1 1345076 1345912 D hypothetical protein 1345076..1345912 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851882 YP_001652225.1 CDS tehA NC_010278.1 1345991 1346938 R potassium-tellurite ethidium and proflavin transporter complement(1345991..1346938) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851978 YP_001652226.1 CDS APJL_1226 NC_010278.1 1347037 1347687 R hypothetical protein complement(1347037..1347687) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851864 YP_001652227.1 CDS APJL_1227 NC_010278.1 1347925 1348488 R flavin reductase domain-containing protein complement(1347925..1348488) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851830 YP_001652228.1 CDS APJL_1228 NC_010278.1 1348575 1350419 R ABC transporter ATP-binding protein complement(1348575..1350419) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851814 YP_001652229.1 CDS luxS NC_010278.1 1350525 1351034 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(1350525..1351034) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851794 YP_001652230.1 CDS APJL_1230 NC_010278.1 1351089 1353617 R hypothetical protein complement(1351089..1353617) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851841 YP_001652231.1 CDS fur NC_010278.1 1353903 1354352 R ferric uptake regulation protein complement(1353903..1354352) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851786 YP_001652232.1 CDS fldA NC_010278.1 1354381 1354905 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(1354381..1354905) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851897 YP_001652233.1 CDS APJL_1233 NC_010278.1 1354927 1355220 R LexA regulated protein complement(1354927..1355220) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851940 YP_001652234.1 CDS APJL_1234 NC_010278.1 1355420 1355896 R hypothetical protein complement(1355420..1355896) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851992 YP_001652235.1 CDS APJL_1235 NC_010278.1 1355988 1356989 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1355988..1356989 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851827 YP_001652236.1 CDS APJL_1236 NC_010278.1 1357050 1358345 D xanthine/uracil family permease 1357050..1358345 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851744 YP_001652237.1 CDS APJL_1237 NC_010278.1 1358455 1358805 D hypothetical protein 1358455..1358805 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852030 YP_001652238.1 CDS APJL_1238 NC_010278.1 1358805 1359992 D flavoprotein 1358805..1359992 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851944 YP_001652239.1 CDS infA NC_010278.1 1360070 1360288 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1360070..1360288) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851612 YP_001652240.1 CDS aphA NC_010278.1 1360380 1361042 R AphA (smp-like) protein complement(1360380..1361042) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851697 YP_001652241.1 CDS serB NC_010278.1 1361135 1362004 D phosphoserine phosphatase 1361135..1362004 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851855 YP_001652242.1 CDS APJL_1242 NC_010278.1 1362054 1362545 D putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 1362054..1362545 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851968 YP_001652243.1 CDS APJL_1243 NC_010278.1 1362594 1362791 D hypothetical protein 1362594..1362791 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851736 YP_001652244.1 CDS glgP NC_010278.1 1362899 1365298 D glucan phosphorylase 1362899..1365298 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851878 YP_001652245.1 CDS malT NC_010278.1 1365376 1368093 R ATP-dependent transcriptional regulator complement(1365376..1368093) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851989 YP_001652246.1 CDS APJL_1246 NC_010278.1 1368208 1369092 R maltose regulon periplasmic protein complement(1368208..1369092) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851748 YP_001652247.1 CDS lamB NC_010278.1 1369164 1370456 R porin involved in the transport of maltose and maltodextrins; maltoporin complement(1369164..1370456) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851495 YP_001652248.1 CDS malK NC_010278.1 1370526 1371665 R with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein complement(1370526..1371665) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851936 YP_001652249.1 CDS malE NC_010278.1 1371996 1373180 D functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 1371996..1373180 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852001 YP_001652250.1 CDS malF NC_010278.1 1373259 1374809 D with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 1373259..1374809 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851278 YP_001652251.1 CDS malG NC_010278.1 1374860 1375750 D with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 1374860..1375750 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851475 YP_001652252.1 CDS malQ NC_010278.1 1375841 1377859 D amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1375841..1377859 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851948 YP_001652253.1 CDS APJL_1253 NC_010278.1 1378077 1379663 D carbon starvation protein, membrane protein 1378077..1379663 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852007 YP_001652254.1 CDS APJL_1254 NC_010278.1 1379729 1380523 D putative deoxyribonuclease 1379729..1380523 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851923 YP_001652255.1 CDS lpd NC_010278.1 1380585 1381955 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(1380585..1381955) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852839 YP_001652256.1 CDS APJL_1256 NC_010278.1 1382041 1382559 R hypothetical protein complement(1382041..1382559) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851993 YP_001652257.1 CDS APJL_1257 NC_010278.1 1382661 1383299 R putative NAD(P)H nitroreductase complement(1382661..1383299) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851887 YP_001652258.1 CDS APJL_1258 NC_010278.1 1383462 1383755 R hypothetical protein complement(1383462..1383755) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851849 YP_001652259.1 CDS APJL_1259 NC_010278.1 1383755 1384414 R AzlC family protein complement(1383755..1384414) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851764 YP_001652260.1 CDS sapF NC_010278.1 1384488 1385288 R peptide transport system ATP-binding protein complement(1384488..1385288) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851862 YP_001652261.1 CDS fba NC_010278.1 1385404 1386480 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(1385404..1386480) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851931 YP_001652262.1 CDS pgk NC_010278.1 1386581 1387756 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1386581..1387756) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851506 YP_001652263.1 CDS APJL_1263 NC_010278.1 1387914 1389302 R hypothetical protein complement(1387914..1389302) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851969 YP_001652264.1 CDS APJL_1264 NC_010278.1 1389535 1390809 R di- and tricarboxylate transporter complement(1389535..1390809) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851865 YP_001652265.1 CDS APJL_1265 NC_010278.1 1391114 1392505 R di- and tricarboxylate transporter complement(1391114..1392505) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851941 YP_001652266.1 CDS parE NC_010278.1 1392701 1394614 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1392701..1394614) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852033 YP_001652267.1 CDS phoR NC_010278.1 1394692 1395984 R phosphate regulon sensor protein complement(1394692..1395984) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851685 YP_001652268.1 CDS phoB NC_010278.1 1395984 1396625 R phosphate regulon transcriptional regulatory protein complement(1395984..1396625) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852037 YP_001652269.1 CDS pstB NC_010278.1 1396800 1397579 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1396800..1397579) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851669 YP_001652270.1 CDS pstA NC_010278.1 1397588 1398439 R phosphate ABC transporter permease complement(1397588..1398439) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852055 YP_001652271.1 CDS pstC NC_010278.1 1398439 1399392 R phosphate transport system permease protein complement(1398439..1399392) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852043 YP_001652272.1 CDS pstS NC_010278.1 1399541 1400584 R phosphate-binding periplasmic protein complement(1399541..1400584) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852046 YP_001652273.1 CDS APJL_1273 NC_010278.1 1400706 1401092 R heavy metal-dependent transcriptional regulator complement(1400706..1401092) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852063 YP_001652274.1 CDS APJL_1274 NC_010278.1 1401178 1401630 D metal-binding protein 1401178..1401630 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852050 YP_001652275.1 CDS APJL_1275 NC_010278.1 1401648 1401848 D cation transport ATPase 1401648..1401848 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852069 YP_001652276.1 CDS copA NC_010278.1 1402087 1404237 D copper-transporting P-type ATPase 1402087..1404237 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852042 YP_001652277.1 CDS APJL_1277 NC_010278.1 1404335 1405156 R putative oxidoreductase complement(1404335..1405156) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852073 YP_001652278.1 CDS APJL_1278 NC_010278.1 1405184 1405747 R nitroreductase complement(1405184..1405747) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852072 YP_001652279.1 CDS sppA NC_010278.1 1405862 1407718 D protease IV, signal peptide peptidase 1405862..1407718 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852053 YP_001652280.1 CDS APJL_1280 NC_010278.1 1407877 1408620 D ribonuclease 1407877..1408620 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852058 YP_001652281.1 CDS sprT NC_010278.1 1408651 1409142 D hypothetical protein 1408651..1409142 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852060 YP_001652282.1 CDS ndh NC_010278.1 1409247 1410533 D NADH dehydrogenase 1409247..1410533 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852061 YP_001652283.1 CDS APJL_1283 NC_010278.1 1410723 1413062 R transcriptional accessory protein complement(1410723..1413062) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852065 YP_001652284.1 CDS pilF NC_010278.1 1413137 1413685 R putative fimbrial biogenesis and twitching motility protein PilF-like protein complement(1413137..1413685) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852067 YP_001652285.1 CDS APJL_1285 NC_010278.1 1413739 1414920 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(1413739..1414920) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852088 YP_001652286.1 CDS gltX NC_010278.1 1415825 1417264 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1415825..1417264 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852856 YP_001652287.1 CDS APJL_1287 NC_010278.1 1417602 1417853 D Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 1417602..1417853 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852092 YP_001652288.1 CDS yoeB NC_010278.1 1417850 1418110 D toxin YoeB 1417850..1418110 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852114 YP_001652289.1 CDS APJL_1289 NC_010278.1 1418268 1418435 R hypothetical protein complement(1418268..1418435) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852104 YP_001652290.1 CDS lpxK NC_010278.1 1418437 1419417 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(1418437..1419417) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852106 YP_001652291.1 CDS clpX NC_010278.1 1419511 1420647 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1419511..1420647) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852105 YP_001652292.1 CDS clpP NC_010278.1 1420770 1421360 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1420770..1421360) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852107 YP_001652293.1 CDS sufE NC_010278.1 1421484 1421876 D hypothetical protein 1421484..1421876 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852108 YP_001652294.1 CDS dnaQ NC_010278.1 1422235 1423008 R DNA polymerase III subunit epsilon complement(1422235..1423008) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852124 YP_001652295.1 CDS APJL_1295 NC_010278.1 1423095 1424765 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(1423095..1424765) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852123 YP_001652296.1 CDS APJL_1296 NC_010278.1 1424930 1425268 D putative gamma-carboxymuconolactone decarboxylase subunit 1424930..1425268 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852120 YP_001652297.1 CDS APJL_1297 NC_010278.1 1425261 1425629 D rhodanese-related sulfurtransferase 1425261..1425629 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852146 YP_001652298.1 CDS APJL_1298 NC_010278.1 1425738 1426058 D hypothetical protein 1425738..1426058 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852627 YP_001652299.1 CDS murA NC_010278.1 1426116 1427390 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1426116..1427390) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852655 YP_001652300.1 CDS APJL_1300 NC_010278.1 1427510 1427770 R transcriptional regulator complement(1427510..1427770) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852650 YP_001652301.1 CDS APJL_1301 NC_010278.1 1427783 1428136 R putative anti-sigma factor B antagonist complement(1427783..1428136) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852681 YP_001652302.1 CDS APJL_1302 NC_010278.1 1428146 1428784 R organic solvent resistance ABC transporter auxiliary protein complement(1428146..1428784) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852698 YP_001652303.1 CDS APJL_1303 NC_010278.1 1428856 1429383 R organic solvent resistance ABC transporter periplasmic protein complement(1428856..1429383) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852776 YP_001652304.1 CDS APJL_1304 NC_010278.1 1429402 1430178 R permease complement(1429402..1430178) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852553 YP_001652305.1 CDS APJL_1305 NC_010278.1 1430171 1430974 R ABC transporter ATP-binding protein complement(1430171..1430974) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852284 YP_001652306.1 CDS degP NC_010278.1 1431235 1432629 D serine protease 1431235..1432629 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852293 YP_001652307.1 CDS APJL_1307 NC_010278.1 1432668 1433555 R hypothetical protein complement(1432668..1433555) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852434 YP_001652308.1 CDS argR NC_010278.1 1433555 1434016 R regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor complement(1433555..1434016) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852590 YP_001652309.1 CDS mdh NC_010278.1 1434210 1435163 D oxidizes malate to oxaloacetate; malate dehydrogenase 1434210..1435163 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852257 YP_001652310.1 CDS APJL_1310 NC_010278.1 1435253 1435522 D hypothetical protein 1435253..1435522 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852316 YP_001652311.1 CDS adk NC_010278.1 1435590 1436234 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(1435590..1436234) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852328 YP_001652312.1 CDS APJL_1312 NC_010278.1 1436386 1438509 R iron-regulated outer membrane protein complement(1436386..1438509) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852337 YP_001652313.1 CDS ampG NC_010278.1 1438686 1439966 R permease and signal transducer complement(1438686..1439966) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852487 YP_001652314.1 CDS galE NC_010278.1 1440105 1441121 R UDP-glucose-4-epimerase complement(1440105..1441121) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852495 YP_001652315.1 CDS ligA NC_010278.1 1441187 1443235 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(1441187..1443235) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852592 YP_001652316.1 CDS zipA NC_010278.1 1443299 1444309 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(1443299..1444309) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852119 YP_001652317.1 CDS cysZ NC_010278.1 1444429 1445310 D putative role in sulfur assimilation; putative sulfate transport protein CysZ 1444429..1445310 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852157 YP_001652318.1 CDS APJL_1318 NC_010278.1 1445370 1445696 R hypothetical protein complement(1445370..1445696) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852382 YP_001652319.1 CDS gnd NC_010278.1 1445788 1447242 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(1445788..1447242) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852571 YP_001652320.1 CDS APJL_1320 NC_010278.1 1447455 1447955 R hypothetical protein complement(1447455..1447955) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852160 YP_001652321.1 CDS racX NC_010278.1 1448094 1448783 R RacX protein complement(1448094..1448783) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852616 YP_001652322.1 CDS APJL_1322 NC_010278.1 1448886 1450205 R putative transport protein complement(1448886..1450205) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852138 YP_001652323.1 CDS nagB1 NC_010278.1 1450338 1451036 R 6-phosphogluconolactonase complement(1450338..1451036) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852144 YP_001652324.1 CDS zwf NC_010278.1 1451123 1452610 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1451123..1452610) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852134 YP_001652325.1 CDS cysQ NC_010278.1 1452682 1453497 R 3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase complement(1452682..1453497) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852198 YP_001652326.1 CDS nudE NC_010278.1 1453510 1454067 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(1453510..1454067) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852139 YP_001652327.1 CDS hslR NC_010278.1 1454210 1454614 D heat shock protein 15-like protein 1454210..1454614 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852203 YP_001652328.1 CDS hslO NC_010278.1 1454745 1455635 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 1454745..1455635 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852489 YP_001652329.1 CDS dcuB2 NC_010278.1 1455703 1457037 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(1455703..1457037) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852133 YP_001652330.1 CDS APJL_1330 NC_010278.1 1457267 1457437 D hypothetical protein 1457267..1457437 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852147 YP_001652331.1 CDS argF NC_010278.1 1457902 1458906 D ornithine carbamoyltransferase 1457902..1458906 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852148 YP_001652332.1 CDS arcC NC_010278.1 1458928 1459875 D reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 1458928..1459875 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852151 YP_001652333.1 CDS ptsB NC_010278.1 1460123 1461544 R phosphotransferase system enzyme II,sucrose-specific, factor IIBC complement(1460123..1461544) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852159 YP_001652334.1 CDS thiQ NC_010278.1 1461734 1462378 R thiamin ABC transporterATP-binding protein complement(1461734..1462378) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852162 YP_001652335.1 CDS thiP NC_010278.1 1462375 1464000 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(1462375..1464000) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852185 YP_001652336.1 CDS ptsH NC_010278.1 1464237 1464494 D PTS system phosphocarrier protein HPr 1464237..1464494 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852243 YP_001652337.1 CDS ptsI NC_010278.1 1464618 1466339 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 1464618..1466339 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852248 YP_001652338.1 CDS crr NC_010278.1 1466424 1466924 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 1466424..1466924 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852310 YP_001652339.1 CDS APJL_1339 NC_010278.1 1467146 1468537 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1467146..1468537 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852317 YP_001652340.1 CDS uvrD NC_010278.1 1468739 1470937 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 1468739..1470937 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852401 YP_001652341.1 CDS hypB NC_010278.1 1471141 1471950 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 1471141..1471950 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852465 YP_001652342.1 CDS hypD NC_010278.1 1471962 1473077 D hydrogenase maturation factor 1471962..1473077 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852469 YP_001652343.1 CDS hypE NC_010278.1 1473151 1474092 D hydrogenase maturation factor 1473151..1474092 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852471 YP_001652344.1 CDS apxIIID NC_010278.1 1474432 1475865 R RTX-III toxin determinant D complement(1474432..1475865) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852537 YP_001652345.1 CDS apxIIIB NC_010278.1 1475877 1478000 R toxin RTX-III translocation ATP-binding protein (RTX-III toxin determinant B) complement(1475877..1478000) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852539 YP_001652346.1 CDS apxIIIA NC_010278.1 1478069 1481227 R RTX-III toxin determinant A from serotype 8 complement(1478069..1481227) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852555 YP_001652347.1 CDS apxIIIC NC_010278.1 1481231 1481647 R hemolysin-activating lysine-acyltransferase HlyC complement(1481231..1481647) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852566 YP_001652348.1 CDS hypF NC_010278.1 1482195 1484498 R hydrogenase maturation factor complement(1482195..1484498) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852612 YP_001652349.1 CDS hyaA NC_010278.1 1484733 1485875 D involved in hydrogen uptake; hydrogenase 2 small subunit 1484733..1485875 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852618 YP_001652350.1 CDS hybA2 NC_010278.1 1485868 1486905 D Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 1485868..1486905 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852625 YP_001652351.1 CDS cytB NC_010278.1 1486898 1488079 D HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit 1486898..1488079 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852691 YP_001652352.1 CDS hyaB NC_010278.1 1488076 1489785 D involved in hydrogen uptake; hydrogenase 2 large subunit 1488076..1489785 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852694 YP_001652353.1 CDS hybD NC_010278.1 1489785 1490282 D protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 1489785..1490282 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852696 YP_001652354.1 CDS hybE NC_010278.1 1490275 1490778 D hydrogenase 2-specific chaperone 1490275..1490778 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852707 YP_001652355.1 CDS hypC NC_010278.1 1490806 1491084 D hydrogenase 2 accessory protein HypG 1490806..1491084 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852710 YP_001652356.1 CDS hybF NC_010278.1 1491179 1491520 R hydrogenase nickel incorporation protein hybF complement(1491179..1491520) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852722 YP_001652357.1 CDS mfd NC_010278.1 1492435 1495884 R transcription repair coupling factor complement(1492435..1495884) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852281 YP_001652358.1 CDS pepN NC_010278.1 1495986 1498595 D aminopeptidase N 1495986..1498595 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852576 YP_001652359.1 CDS APJL_1359 NC_010278.1 1498733 1499323 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY complement(1498733..1499323) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852783 YP_001652360.1 CDS folB NC_010278.1 1499395 1499748 D dihydroneopterin aldolase 1499395..1499748 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852679 YP_001652361.1 CDS cdd NC_010278.1 1499857 1500750 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1499857..1500750 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852296 YP_001652362.1 CDS ftsX NC_010278.1 1500797 1501735 R putative ABC transporter, membrane protein; cell division protein FtsX complement(1500797..1501735) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852810 YP_001652363.1 CDS fstE NC_010278.1 1501745 1502311 R cell division ATP-binding protein complement(1501745..1502311) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852808 YP_001652364.1 CDS ftsY NC_010278.1 1502489 1504210 R cell division protein complement(1502489..1504210) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852805 YP_001652365.1 CDS APJL_1365 NC_010278.1 1504288 1504881 D putative methylase 1504288..1504881 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852788 YP_001652366.1 CDS APJL_1366 NC_010278.1 1504946 1505257 D highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1504946..1505257 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852817 YP_001652367.1 CDS hpaC NC_010278.1 1505273 1505785 D 4-hydroxyphenylacetic acid hydroxylase 1505273..1505785 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852853 YP_001652368.1 CDS tehB NC_010278.1 1505900 1506772 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1505900..1506772 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851013 YP_001652369.1 CDS artM NC_010278.1 1506900 1507583 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(1506900..1507583) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851459 YP_001652370.1 CDS artQ NC_010278.1 1507583 1508254 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(1507583..1508254) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851664 YP_001652371.1 CDS artI NC_010278.1 1508260 1508979 R amino acid ABC transporter periplasmic protein complement(1508260..1508979) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852828 YP_001652372.1 CDS artP NC_010278.1 1508999 1509733 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(1508999..1509733) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851363 YP_001652373.1 CDS APJL_1373 NC_010278.1 1509958 1510455 R phospholipid-binding protein complement(1509958..1510455) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851048 YP_001652374.1 CDS APJL_1374 NC_010278.1 1510528 1511490 D putative sodium/calcium exchange protein 1510528..1511490 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851621 YP_001652375.1 CDS APJL_1375 NC_010278.1 1511568 1511861 R transcriptional regulator complement(1511568..1511861) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851329 YP_001652376.1 CDS APJL_1376 NC_010278.1 1511842 1512213 R hypothetical protein complement(1511842..1512213) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851953 YP_001652377.1 CDS dipZ NC_010278.1 1512443 1514158 D two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 1512443..1514158 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851708 YP_001652378.1 CDS APJL_1378 NC_010278.1 1514216 1514785 D hypothetical protein 1514216..1514785 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851616 YP_001652379.1 CDS APJL_1379 NC_010278.1 1514829 1515683 R hypothetical protein complement(1514829..1515683) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851067 YP_001652380.1 CDS APJL_1380 NC_010278.1 1515756 1517504 D hypothetical protein 1515756..1517504 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851656 YP_001652381.1 CDS APJL_1381 NC_010278.1 1517479 1517850 D hypothetical protein 1517479..1517850 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851328 YP_001652382.1 CDS APJL_1382 NC_010278.1 1517859 1518437 D phosphoheptose isomerase 1517859..1518437 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850758 YP_001652383.1 CDS APJL_1383 NC_010278.1 1518459 1519046 D hypothetical protein 1518459..1519046 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851684 YP_001652384.1 CDS APJL_1384 NC_010278.1 1519258 1520565 R YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase complement(1519258..1520565) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852611 YP_001652385.1 CDS ccmF NC_010278.1 1521496 1523445 R cytochrome c-type biogenesis protein complement(1521496..1523445) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851341 YP_001652386.1 CDS ccmE NC_010278.1 1523445 1523990 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(1523445..1523990) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851641 YP_001652387.1 CDS ccmD NC_010278.1 1524174 1524371 R heme exporter protein D complement(1524174..1524371) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850869 YP_001652388.1 CDS ccmC NC_010278.1 1524384 1525115 R cytochrome c-type biogenesis protein complement(1524384..1525115) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850873 YP_001652389.1 CDS ccmB NC_010278.1 1525166 1525828 R cytochrome c-type biogenesis protein complement(1525166..1525828) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850750 YP_001652390.1 CDS ccmA2 NC_010278.1 1525825 1526460 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(1525825..1526460) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850759 YP_001652391.1 CDS yfgE NC_010278.1 1526601 1527311 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(1526601..1527311) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851142 YP_001652392.1 CDS APJL_1392 NC_010278.1 1533305 1534138 D hypothetical protein 1533305..1534138 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851242 YP_001652393.1 CDS APJL_1393 NC_010278.1 1534313 1534579 D catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide; oxaloacetate decarboxylase subunit gamma 1534313..1534579 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851623 YP_001652394.1 CDS oadA NC_010278.1 1534595 1536397 D catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 1534595..1536397 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850860 YP_001652395.1 CDS oadB NC_010278.1 1536414 1537718 D oxaloacetate decarboxylase subunit beta 1536414..1537718 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850851 YP_001652396.1 CDS phnA NC_010278.1 1537851 1538174 D alkylphosphonate uptake protein 1537851..1538174 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851057 YP_001652397.1 CDS mauG NC_010278.1 1538346 1539746 D cytochrome c peroxidase 1538346..1539746 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851007 YP_001652398.1 CDS APJL_1398 NC_010278.1 1539812 1540108 R hypothetical protein complement(1539812..1540108) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850890 YP_001652399.1 CDS APJL_1399 NC_010278.1 1540110 1540643 R integral membrane protein complement(1540110..1540643) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851049 YP_001652400.1 CDS APJL_1400 NC_010278.1 1540765 1541106 R hypothetical protein complement(1540765..1541106) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850774 YP_001652401.1 CDS trmB NC_010278.1 1541162 1541914 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(1541162..1541914) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851287 YP_001652402.1 CDS fabH NC_010278.1 1541962 1542912 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(1541962..1542912) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850786 YP_001652403.1 CDS plsX NC_010278.1 1542924 1543958 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX complement(1542924..1543958) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850796 YP_001652404.1 CDS rpmF NC_010278.1 1543983 1544153 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(1543983..1544153) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850734 YP_001652405.1 CDS APJL_1405 NC_010278.1 1544171 1544695 R hypothetical protein complement(1544171..1544695) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850852 YP_001652406.1 CDS APJL_1406 NC_010278.1 1544915 1545706 D inner membrane protein 1544915..1545706 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850893 YP_001652407.1 CDS APJL_1407 NC_010278.1 1545802 1547064 D hypothetical protein 1545802..1547064 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851240 YP_001652408.1 CDS APJL_1408 NC_010278.1 1547443 1548957 D SNF family Na(+)-dependent transporter 1547443..1548957 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850897 YP_001652409.1 CDS APJL_1409 NC_010278.1 1548968 1549060 D hypothetical protein 1548968..1549060 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851103 YP_001652410.1 CDS APJL_1410 NC_010278.1 1549344 1550315 D phosphotransferase system enzyme II,mannose-specific, factor IIAB 1549344..1550315 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851040 YP_001652411.1 CDS APJL_1411 NC_010278.1 1550328 1551128 D PTS system mannose-specific transporter subunit IIC 1550328..1551128 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851302 YP_001652412.1 CDS APJL_1412 NC_010278.1 1551142 1551978 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1551142..1551978 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851008 YP_001652413.1 CDS APJL_1413 NC_010278.1 1552077 1552535 D hypothetical protein 1552077..1552535 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850950 YP_001652414.1 CDS manA NC_010278.1 1552532 1553737 D mannose-6-phosphate isomerase 1552532..1553737 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851254 YP_001652415.1 CDS APJL_1415 NC_010278.1 1553799 1554311 D hypothetical protein 1553799..1554311 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851027 YP_001652416.1 CDS afuA1 NC_010278.1 1554557 1555597 D AfuA protein 1554557..1555597 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851074 YP_001652417.1 CDS afuB1 NC_010278.1 1555703 1557766 D ABC-type thiamine transport system permease 1555703..1557766 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851080 YP_001652418.1 CDS fbpC NC_010278.1 1557792 1558859 D Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 1557792..1558859 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851100 YP_001652419.1 CDS mpl NC_010278.1 1558950 1560314 R UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase complement(1558950..1560314) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851117 YP_001652420.1 CDS fbp NC_010278.1 1560437 1561441 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1560437..1561441 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850928 YP_001652421.1 CDS APJL_1421 NC_010278.1 1561597 1562385 R hypothetical protein complement(1561597..1562385) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851123 YP_001652422.1 CDS tufB1 NC_010278.1 1562676 1563860 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1562676..1563860) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851143 YP_001652423.1 CDS rpsG NC_010278.1 1566128 1566598 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1566128..1566598) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850882 YP_001652424.1 CDS rpsL NC_010278.1 1566735 1567109 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1566735..1567109) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850777 YP_001652425.1 CDS rfaC NC_010278.1 1567231 1568190 R ADP-heptose--LPS heptosyltransferase complement(1567231..1568190) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850790 YP_001652426.1 CDS rfaF NC_010278.1 1568265 1569302 R ADP-heptose LPS heptosyltransferase complement(1568265..1569302) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850871 YP_001652427.1 CDS APJL_1429 NC_010278.1 1569384 1569836 R hypothetical protein complement(1569384..1569836) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850889 YP_001652428.1 CDS oapA NC_010278.1 1569910 1571301 R opacity associated protein A complement(1569910..1571301) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851661 YP_001652429.1 CDS APJL_1431 NC_010278.1 1571602 1571946 D DNA uptake protein and related DNA-binding protein 1571602..1571946 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851354 YP_001652430.1 CDS psd NC_010278.1 1572097 1572987 D catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 1572097..1572987 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851387 YP_001652431.1 CDS APJL_1433 NC_010278.1 1573104 1575446 D Type I restriction enzyme EcoEI R protein 1573104..1575446 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850875 YP_001652432.1 CDS hsdM NC_010278.1 1575530 1576999 D Type I restriction-modification system M subunit 1575530..1576999 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851238 YP_001652433.1 CDS APJL_1435 NC_010278.1 1577008 1578003 D putative DNA binding protein 1577008..1578003 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851122 YP_001652434.1 CDS APJL_1436 NC_010278.1 1578057 1579469 D Type I restriction enzyme EcoAI specificity protein 1578057..1579469 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851197 YP_001652435.1 CDS APJL_1437 NC_010278.1 1579521 1580321 D integrase 1579521..1580321 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851183 YP_001652436.1 CDS APJL_1438 NC_010278.1 1580364 1581584 R Type I restriction-modification system S subunit complement(1580364..1581584) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851189 YP_001652437.1 CDS gshA NC_010278.1 1581826 1584099 D Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1581826..1584099 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851148 YP_001652438.1 CDS APJL_1440 NC_010278.1 1584191 1584811 R CueR-like transcriptional regulator complement(1584191..1584811) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850891 YP_001652439.1 CDS tnaB NC_010278.1 1585077 1586213 D tryptophan-specific transport protein 1585077..1586213 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851081 YP_001652440.1 CDS APJL_1442 NC_010278.1 1586278 1586571 R hypothetical protein complement(1586278..1586571) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850998 YP_001652441.1 CDS fAA1 NC_010278.1 1587671 1589446 R long-chain acyl-CoA synthetase complement(1587671..1589446) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850866 YP_001652442.1 CDS mqo NC_010278.1 1589627 1591102 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(1589627..1591102) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850911 YP_001652443.1 CDS APJL_1447 NC_010278.1 1591210 1591623 R hypothetical protein complement(1591210..1591623) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850728 YP_001652444.1 CDS APJL_1448 NC_010278.1 1591843 1592184 D hypothetical protein 1591843..1592184 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851023 YP_001652445.1 CDS APJL_1449 NC_010278.1 1592226 1592651 D hypothetical protein 1592226..1592651 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851310 YP_001652446.1 CDS mglC NC_010278.1 1592722 1593735 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(1592722..1593735) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850927 YP_001652447.1 CDS mglA NC_010278.1 1593752 1595251 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(1593752..1595251) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851167 YP_001652448.1 CDS rbsB1 NC_010278.1 1595314 1596306 R periplasmic sugar-binding protein complement(1595314..1596306) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851177 YP_001652449.1 CDS momP1 NC_010278.1 1596560 1597666 R major outer membrane protein complement(1596560..1597666) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850797 YP_001652450.1 CDS APJL_1454 NC_010278.1 1598094 1601183 D hypothetical protein 1598094..1601183 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850740 YP_001652451.1 CDS APJL_1455 NC_010278.1 1601316 1601741 D hypothetical protein 1601316..1601741 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850733 YP_001652452.1 CDS yidC NC_010278.1 1601895 1603523 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 1601895..1603523 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850727 YP_001652453.1 CDS napC NC_010278.1 1603808 1604422 R nitrate/TMAO reductase, membrane-bound tetraheme cytochrome c subunit complement(1603808..1604422) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850952 YP_001652454.1 CDS napB NC_010278.1 1604434 1604856 R nitrate reductase cytochrome c-type subunit complement(1604434..1604856) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851075 YP_001652455.1 CDS napH NC_010278.1 1604875 1605768 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(1604875..1605768) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850815 YP_001652456.1 CDS napG NC_010278.1 1605768 1606673 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(1605768..1606673) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850896 YP_001652457.1 CDS napA NC_010278.1 1606808 1609291 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(1606808..1609291) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850761 YP_001652458.1 CDS napD NC_010278.1 1609323 1609592 R periplasmic nitrate reductase subunit NapD complement(1609323..1609592) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851200 YP_001652459.1 CDS napF NC_010278.1 1609595 1610125 R ferredoxin-type protein complement(1609595..1610125) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851192 YP_001652460.1 CDS APJL_1464 NC_010278.1 1610324 1610899 D putative NAD(P)H oxidoreductase 1610324..1610899 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851056 YP_001652461.1 CDS APJL_1465 NC_010278.1 1611053 1611853 R transposase complement(1611053..1611853) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851098 YP_001652462.1 CDS APJL_1466 NC_010278.1 1611859 1612368 R transposase and inactivated derivative complement(1611859..1612368) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851034 YP_001652463.1 CDS APJL_1467 NC_010278.1 1612472 1612984 R hypothetical protein complement(1612472..1612984) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850836 YP_001652464.1 CDS rne NC_010278.1 1613145 1616132 R ribonuclease E complement(1613145..1616132) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851136 YP_001652465.1 CDS APJL_1469 NC_010278.1 1616602 1617609 D hypothetical protein 1616602..1617609 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850802 YP_001652466.1 CDS APJL_1470 NC_010278.1 1617679 1618200 R hypothetical protein complement(1617679..1618200) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851144 YP_001652467.1 CDS ubiD NC_010278.1 1618350 1619813 R 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1618350..1619813) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851121 YP_001652468.1 CDS znuA NC_010278.1 1619959 1620936 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1619959..1620936 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850850 YP_001652469.1 CDS APJL_1473 NC_010278.1 1621035 1621823 R hypothetical protein complement(1621035..1621823) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851606 YP_001652470.1 CDS serA NC_010278.1 1622110 1623339 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(1622110..1623339) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850985 YP_001652471.1 CDS rpiA NC_010278.1 1623483 1624142 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(1623483..1624142) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851296 YP_001652472.1 CDS glmM NC_010278.1 1624289 1625623 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1624289..1625623) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850766 YP_001652473.1 CDS ilvA NC_010278.1 1625695 1627221 R threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase complement(1625695..1627221) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850732 YP_001652474.1 CDS slyD NC_010278.1 1627347 1627940 R FkbP-type peptidyl-prolyl cis-trans isomerase complement(1627347..1627940) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850719 YP_001652475.1 CDS aqpZ NC_010278.1 1628289 1628975 R aquaporin Z, transmembrane water channel complement(1628289..1628975) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851651 YP_001652476.1 CDS APJL_1480 NC_010278.1 1629121 1629837 R periplasmic/secreted protein complement(1629121..1629837) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851011 YP_001652477.1 CDS APJL_1481 NC_010278.1 1629879 1630634 R hypothetical protein complement(1629879..1630634) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851309 YP_001652478.1 CDS APJL_1482 NC_010278.1 1630779 1631699 D hypothetical protein 1630779..1631699 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851029 YP_001652479.1 CDS menA NC_010278.1 1631699 1632607 D catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1631699..1632607 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851009 YP_001652480.1 CDS APJL_1484 NC_010278.1 1632685 1633026 R essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA complement(1632685..1633026) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851300 YP_001652481.1 CDS wzz NC_010278.1 1633173 1634285 D Wzz-like protein 1633173..1634285 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851140 YP_001652482.1 CDS rfaG NC_010278.1 1634336 1635091 D lipopolysaccharide biosynthesis glycosyltransferase 1634336..1635091 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851261 YP_001652483.1 CDS APJL_1487 NC_010278.1 1635112 1636179 D VI polysaccharide biosynthesis protein 1635112..1636179 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851268 YP_001652484.1 CDS APJL_1488 NC_010278.1 1636188 1637240 D glycosyltransferase 1636188..1637240 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851264 YP_001652485.1 CDS APJL_1489 NC_010278.1 1637257 1638306 D hypothetical protein 1637257..1638306 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851519 YP_001652486.1 CDS wzy NC_010278.1 1638309 1639640 D oligosaccharide repeat-containing polymerase 1638309..1639640 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851252 YP_001652487.1 CDS wzx NC_010278.1 1639637 1641088 D flippase Wzx 1639637..1641088 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851246 YP_001652488.1 CDS glf NC_010278.1 1641131 1642228 D UDP-galactopyranose mutase 1641131..1642228 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851233 YP_001652489.1 CDS APJL_1493 NC_010278.1 1642246 1643556 D putative sugar transferase 1642246..1643556 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851250 YP_001652490.1 CDS APJL_1494 NC_010278.1 1643560 1644039 D acyltransferase 3 1643560..1644039 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851243 YP_001652491.1 CDS APJL_1495 NC_010278.1 1644206 1644619 D hypothetical protein 1644206..1644619 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851088 YP_001652492.1 CDS APJL_1496 NC_010278.1 1644767 1645684 D polysacchride biosynthesis protein 1644767..1645684 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851231 YP_001652493.1 CDS rmlB NC_010278.1 1645698 1646771 D dTDP-glucose 4,6-dehydratase 1645698..1646771 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851611 YP_001652494.1 CDS rpsU NC_010278.1 1647009 1647224 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1647009..1647224 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851225 YP_001652495.1 CDS dnaG NC_010278.1 1647401 1649143 D synthesizes RNA primers at the replication forks; DNA primase 1647401..1649143 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850969 YP_001652496.1 CDS rpoD NC_010278.1 1649248 1651107 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1649248..1651107 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851256 YP_001652497.1 CDS tyrS NC_010278.1 1651260 1652450 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1651260..1652450) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851211 YP_001652498.1 CDS APJL_1502 NC_010278.1 1652796 1653260 R hypothetical protein complement(1652796..1653260) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851194 YP_001652499.1 CDS APJL_1503 NC_010278.1 1653374 1655731 R ribonuclease R complement(1653374..1655731) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851193 YP_001652500.1 CDS APJL_1504 NC_010278.1 1655799 1656314 R thioredoxin-like protein complement(1655799..1656314) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850881 YP_001652501.1 CDS APJL_1505 NC_010278.1 1656314 1656946 R negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR complement(1656314..1656946) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851185 YP_001652502.1 CDS oxyR NC_010278.1 1656939 1657832 R Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR complement(1656939..1657832) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850962 YP_001652503.1 CDS APJL_1507 NC_010278.1 1657958 1658692 D hybrid peroxiredoxin hyPrx5 1657958..1658692 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851184 YP_001652504.1 CDS APJL_1508 NC_010278.1 1658920 1659708 D hypothetical protein 1658920..1659708 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850868 YP_001652505.1 CDS APJL_1509 NC_010278.1 1659942 1660574 R hypothetical protein complement(1659942..1660574) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851180 YP_001652506.1 CDS pdxY NC_010278.1 1660978 1661679 R pyridoxine kinase complement(1660978..1661679) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850963 YP_001652507.1 CDS accA NC_010278.1 1662142 1663095 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(1662142..1663095) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851156 YP_001652508.1 CDS sufI1 NC_010278.1 1663212 1664570 R SufI protein complement(1663212..1664570) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851004 YP_001652509.1 CDS plsC NC_010278.1 1664627 1665373 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1664627..1665373) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850909 YP_001652510.1 CDS tpx NC_010278.1 1665516 1666016 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1665516..1666016 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851229 YP_001652511.1 CDS trmE NC_010278.1 1666139 1667497 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1666139..1667497 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850957 YP_001652512.1 CDS APJL_1516 NC_010278.1 1667606 1668961 R hypothetical protein complement(1667606..1668961) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850879 YP_001652513.1 CDS gcvR NC_010278.1 1668974 1669246 R ACT domain-containing protein; hypothetical protein complement(1668974..1669246) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850785 YP_001652514.1 CDS APJL_1518 NC_010278.1 1669384 1670073 R pirin-related protein complement(1669384..1670073) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850979 YP_001652515.1 CDS ftpA NC_010278.1 1670389 1670958 D fine tangled pili major subunit 1670389..1670958 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850935 YP_001652516.1 CDS APJL_1520 NC_010278.1 1671191 1671493 D transcriptional regulator 1671191..1671493 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851163 YP_001652517.1 CDS APJL_1521 NC_010278.1 1671640 1673004 D hypothetical protein 1671640..1673004 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851096 YP_001652518.1 CDS APJL_1522 NC_010278.1 1673072 1675246 R hypothetical protein complement(1673072..1675246) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850737 YP_001652519.1 CDS mgsA NC_010278.1 1675328 1675786 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1675328..1675786) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851030 YP_001652520.1 CDS thrC NC_010278.1 1675919 1677199 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1675919..1677199 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850813 YP_001652521.1 CDS APJL_1525 NC_010278.1 1677285 1677794 D transposase and inactivated derivative 1677285..1677794 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851105 YP_001652522.1 CDS APJL_1526 NC_010278.1 1677800 1678618 D transposase 1677800..1678618 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851083 YP_001652523.1 CDS valS NC_010278.1 1678677 1681541 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1678677..1681541) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850799 YP_001652524.1 CDS APJL_1528 NC_010278.1 1681556 1682032 R hypothetical protein complement(1681556..1682032) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850847 YP_001652525.1 CDS APJL_1529 NC_010278.1 1682284 1682460 R hypothetical protein complement(1682284..1682460) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850912 YP_001652526.1 CDS elaA NC_010278.1 1682620 1683042 R acetyltransferase complement(1682620..1683042) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851205 YP_001652527.1 CDS holC NC_010278.1 1683043 1683480 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(1683043..1683480) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850783 YP_001652528.1 CDS APJL_1532 NC_010278.1 1683754 1684197 D LysM domain/BON superfamily protein 1683754..1684197 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851971 YP_001652529.1 CDS tig NC_010278.1 1684399 1685700 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1684399..1685700 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851732 YP_001652530.1 CDS APJL_1534 NC_010278.1 1685833 1686282 D rhodanese-related sulfurtransferase 1685833..1686282 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851665 YP_001652531.1 CDS secB NC_010278.1 1686307 1686807 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1686307..1686807 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851966 YP_001652532.1 CDS gpsA NC_010278.1 1686992 1688002 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1686992..1688002 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851959 YP_001652533.1 CDS cysE NC_010278.1 1688014 1688829 D catalyzes the O-acetylation of serine; serine acetyltransferase 1688014..1688829 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851702 YP_001652534.1 CDS tufB2 NC_010278.1 1689023 1690207 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1689023..1690207) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851358 YP_001652535.1 CDS coaA NC_010278.1 1690961 1691911 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1690961..1691911 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851478 YP_001652536.1 CDS dsbE1 NC_010278.1 1692046 1692588 D thiol:disulfide interchange protein 1692046..1692588 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851094 YP_001652537.1 CDS ccmH_1 NC_010278.1 1692593 1693060 D cytochrome C-type biogenesis protein 1692593..1693060 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851171 YP_001652538.1 CDS ccmH_2 NC_010278.1 1693060 1693974 D cytochrome C-type biogenesis protein 1693060..1693974 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851251 YP_001652539.1 CDS mogA NC_010278.1 1694046 1694630 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 1694046..1694630 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851279 YP_001652540.1 CDS glnB NC_010278.1 1694750 1695088 D putative nitrogen regulatory protein P-II 1694750..1695088 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851228 YP_001652541.1 CDS lspA NC_010278.1 1695167 1695649 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1695167..1695649 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851166 YP_001652542.1 CDS ispH NC_010278.1 1695650 1696594 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1695650..1696594 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851054 YP_001652543.1 CDS APJL_1547 NC_010278.1 1696594 1696842 D hypothetical protein 1696594..1696842 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851070 YP_001652544.1 CDS APJL_1548 NC_010278.1 1696911 1697510 R nucleoside-diphosphate-sugarepimerase complement(1696911..1697510) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850917 YP_001652545.1 CDS chuW NC_010278.1 1697510 1699327 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1697510..1699327) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850819 YP_001652546.1 CDS gst NC_010278.1 1699484 1700101 R glutathione S-transferase complement(1699484..1700101) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850966 YP_001652547.1 CDS lysA NC_010278.1 1700167 1701417 R diaminopimelate decarboxylase complement(1700167..1701417) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850830 YP_001652548.1 CDS APJL_1552 NC_010278.1 1701540 1701653 R hypothetical protein complement(1701540..1701653) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850921 YP_001652549.1 CDS frdD NC_010278.1 1701831 1702175 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(1701831..1702175) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850823 YP_001652550.1 CDS frdC NC_010278.1 1702188 1702580 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(1702188..1702580) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850903 YP_001652551.1 CDS frdB NC_010278.1 1702589 1703323 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(1702589..1703323) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850731 YP_001652552.1 CDS frdA NC_010278.1 1703336 1705135 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(1703336..1705135) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850804 YP_001652553.1 CDS genX NC_010278.1 1705478 1706461 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 1705478..1706461 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850946 YP_001652554.1 CDS dapF NC_010278.1 1706543 1707367 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(1706543..1707367) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850751 YP_001652555.1 CDS dcuB1 NC_010278.1 1707548 1708870 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 1707548..1708870 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851525 YP_001652556.1 CDS crcB NC_010278.1 1708942 1709313 R CrcB protein complement(1708942..1709313) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851226 YP_001652557.1 CDS APJL_1561 NC_010278.1 1709316 1710380 R putative transport system permease complement(1709316..1710380) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851433 YP_001652558.1 CDS anmK NC_010278.1 1710475 1711584 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1710475..1711584 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850738 YP_001652559.1 CDS murQ NC_010278.1 1711638 1712552 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 1711638..1712552 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850961 YP_001652560.1 CDS prmA NC_010278.1 1712622 1713503 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase complement(1712622..1713503) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851432 YP_001652561.1 CDS APJL_1565 NC_010278.1 1713587 1714054 R N-acetyltransferase GCN5 complement(1713587..1714054) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851353 YP_001652562.1 CDS APJL_1566 NC_010278.1 1714058 1714318 R hypothetical protein complement(1714058..1714318) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851235 YP_001652563.1 CDS tldD NC_010278.1 1714439 1715899 R TldD protein complement(1714439..1715899) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850748 YP_001652564.1 CDS mesJ NC_010278.1 1716029 1717288 D cell-cycle protein 1716029..1717288 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850762 YP_001652565.1 CDS APJL_1569 NC_010278.1 1717315 1717605 R hypothetical protein complement(1717315..1717605) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850745 YP_001652566.1 CDS xerD NC_010278.1 1717607 1718500 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(1717607..1718500) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850718 YP_001652567.1 CDS wecG NC_010278.1 1724762 1725487 R putative UDP-N-acetyl-D-mannosaminuronic acid transferase complement(1724762..1725487) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851895 YP_001652568.1 CDS APJL_1572 NC_010278.1 1725471 1726805 R enterobacterial common antigen polymerase; putative common antigen polymerase complement(1725471..1726805) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851752 YP_001652569.1 CDS wecF NC_010278.1 1726805 1727875 R catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase complement(1726805..1727875) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851912 YP_001652570.1 CDS APJL_1574 NC_010278.1 1728155 1729810 D catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1728155..1729810 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851901 YP_001652571.1 CDS APJL_1575 NC_010278.1 1729913 1730932 D HCP oxidoreductase 1729913..1730932 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851994 YP_001652572.1 CDS wzxE NC_010278.1 1730974 1732224 R lipopolysaccharide biosynthesis protein complement(1730974..1732224) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851823 YP_001652573.1 CDS rffA NC_010278.1 1732212 1733357 R catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase complement(1732212..1733357) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851788 YP_001652574.1 CDS rffC NC_010278.1 1733364 1733987 R TDP-fucosamine acetyltransferase complement(1733364..1733987) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851893 YP_001652575.1 CDS wecC NC_010278.1 1733987 1735258 R catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase complement(1733987..1735258) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852028 YP_001652576.1 CDS wecB NC_010278.1 1735337 1736473 R UDP-N-acetylglucosamine 2-epimerase complement(1735337..1736473) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851374 YP_001652577.1 CDS APJL_1581 NC_010278.1 1736457 1737335 R putative transport protein complement(1736457..1737335) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851050 YP_001652578.1 CDS wecA NC_010278.1 1737370 1738443 R undecaprenyl-phosphatealpha-N- acetylglucosaminyltransferase complement(1737370..1738443) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851903 YP_001652579.1 CDS hemL NC_010278.1 1738742 1740022 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1738742..1740022 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851861 YP_001652580.1 CDS APJL_1584 NC_010278.1 1740077 1741144 R transport system permease complement(1740077..1741144) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851772 YP_001652581.1 CDS mviN NC_010278.1 1741164 1742693 R MviN virulence factor complement(1741164..1742693) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851343 YP_001652582.1 CDS rpsT NC_010278.1 1743127 1743390 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1743127..1743390 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851699 YP_001652583.1 CDS trkA NC_010278.1 1743447 1744823 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein complement(1743447..1744823) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852013 YP_001652584.1 CDS sun NC_010278.1 1744873 1746171 R SUN protein complement(1744873..1746171) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851848 YP_001652585.1 CDS selB NC_010278.1 1746185 1748020 R selenocysteine-specific elongation factor complement(1746185..1748020) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851395 YP_001652586.1 CDS selA NC_010278.1 1748017 1749288 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(1748017..1749288) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851807 YP_001652587.1 CDS mioC NC_010278.1 1749579 1750022 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1749579..1750022 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850803 YP_001652588.1 CDS APJL_1592 NC_010278.1 1750548 1750724 D hypothetical protein 1750548..1750724 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851749 YP_001652589.1 CDS APJL_1593 NC_010278.1 1750742 1750888 D hypothetical protein 1750742..1750888 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851970 YP_001652590.1 CDS xylB1 NC_010278.1 1750860 1752317 R sugar (pentulose and hexulose) kinase complement(1750860..1752317) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851350 YP_001652591.1 CDS APJL_1595 NC_010278.1 1752332 1752727 R gluconolactonase complement(1752332..1752727) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851146 YP_001652592.1 CDS APJL_1596 NC_010278.1 1753150 1753350 R hypothetical protein complement(1753150..1753350) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851693 YP_001652593.1 CDS tbpA1 NC_010278.1 1753826 1756621 R transferrin-binding protein 1 complement(1753826..1756621) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851902 YP_001652594.1 CDS tbpB1 NC_010278.1 1756635 1758095 R transferrin-binding protein 2 complement(1756635..1758095) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851927 YP_001652595.1 CDS exbD1 NC_010278.1 1758306 1758716 R biopolymer transport ExbD protein complement(1758306..1758716) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851776 YP_001652596.1 CDS exbB1 NC_010278.1 1758716 1759384 R biopolymer transport ExbB protein complement(1758716..1759384) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851871 YP_001652597.1 CDS tonB1 NC_010278.1 1759406 1760146 R hypothetical protein complement(1759406..1760146) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851873 YP_001652598.1 CDS APJL_1602 NC_010278.1 1760422 1760670 R hypothetical protein complement(1760422..1760670) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851998 YP_001652599.1 CDS APJL_1603 NC_010278.1 1760677 1760808 R hypothetical protein complement(1760677..1760808) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852023 YP_001652600.1 CDS APJL_1604 NC_010278.1 1760837 1761511 R malate/L-lactate dehydrogenase complement(1760837..1761511) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852019 YP_001652601.1 CDS APJL_1605 NC_010278.1 1761498 1761836 R malate/L-lactate dehydrogenase complement(1761498..1761836) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852015 YP_001652602.1 CDS APJL_1606 NC_010278.1 1762065 1762607 D alpha/beta hydrolase superfamily esterase 1762065..1762607 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852005 YP_001652603.1 CDS APJL_1607 NC_010278.1 1762679 1763233 R hypothetical protein complement(1762679..1763233) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852002 YP_001652604.1 CDS APJL_1608 NC_010278.1 1763341 1764846 R hypothetical protein complement(1763341..1764846) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851755 YP_001652605.1 CDS APJL_1609 NC_010278.1 1764855 1765892 R hypothetical protein complement(1764855..1765892) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851220 YP_001652606.1 CDS APJL_1610 NC_010278.1 1765911 1767281 R hypothetical protein complement(1765911..1767281) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851942 YP_001652607.1 CDS cps3D NC_010278.1 1767486 1769327 R teichoic acid biosynthesis protein complement(1767486..1769327) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851675 YP_001652608.1 CDS cps3C NC_010278.1 1769332 1770480 R Cps7C complement(1769332..1770480) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851951 YP_001652609.1 CDS cps3B NC_010278.1 1770482 1770910 R glycerol-3-phosphate cytidylyltransferase complement(1770482..1770910) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851850 YP_001652610.1 CDS cps3A NC_010278.1 1770964 1772106 R Cps2A complement(1770964..1772106) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851674 YP_001652611.1 CDS cpxD NC_010278.1 1772285 1773472 D HexD, capsule biosynthetic locus protein 1772285..1773472 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851863 YP_001652612.1 CDS cpxC NC_010278.1 1773498 1774655 D capsule polysaccharide export transport system permease 1773498..1774655 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851954 YP_001652613.1 CDS cpxB NC_010278.1 1774727 1775452 D capsule polysaccharide export transport system permease 1774727..1775452 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851869 YP_001652614.1 CDS cpxA NC_010278.1 1775449 1776099 D capsule polysaccharide export transport system ATP-binding protein 1775449..1776099 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851984 YP_001652615.1 CDS modF NC_010278.1 1776298 1777755 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF complement(1776298..1777755) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851775 YP_001652616.1 CDS fmt NC_010278.1 1777848 1778798 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1777848..1778798) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851676 YP_001652617.1 CDS APJL_1621 NC_010278.1 1778961 1779911 R putative immunogenic protein complement(1778961..1779911) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851622 YP_001652618.1 CDS APJL_1622 NC_010278.1 1779946 1780689 D hypothetical protein 1779946..1780689 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852049 YP_001652619.1 CDS trkG NC_010278.1 1780770 1782248 D trk-type K+ transport system, membrane component 1780770..1782248 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852044 YP_001652620.1 CDS APJL_1624 NC_010278.1 1782263 1782790 D flavodoxin 1782263..1782790 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852068 YP_001652621.1 CDS mscL NC_010278.1 1782894 1783283 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 1782894..1783283 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852074 YP_001652622.1 CDS lipA1 NC_010278.1 1783413 1784405 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1783413..1784405) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852103 YP_001652623.1 CDS lipB NC_010278.1 1784470 1785162 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1784470..1785162) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852823 YP_001652624.1 CDS APJL_1628 NC_010278.1 1785194 1785493 R hypothetical protein complement(1785194..1785493) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852659 YP_001652625.1 CDS dacA NC_010278.1 1785627 1786805 R penicillin-binding protein 5 complement(1785627..1786805) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852222 YP_001652626.1 CDS APJL_1630 NC_010278.1 1786901 1787464 R rare lipoprotein A complement(1786901..1787464) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852355 YP_001652627.1 CDS mrdB NC_010278.1 1787639 1788763 R rod-shape-determining protein RodA complement(1787639..1788763) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852225 YP_001652628.1 CDS mrdA NC_010278.1 1788756 1790717 R penicillin binding protein 2 complement(1788756..1790717) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852431 YP_001652629.1 CDS APJL_1633 NC_010278.1 1790799 1791266 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(1790799..1791266) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852621 YP_001652630.1 CDS APJL_1634 NC_010278.1 1791289 1791603 R plant Iojap-like protein complement(1791289..1791603) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852364 YP_001652631.1 CDS mutS NC_010278.1 1791825 1794419 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(1791825..1794419) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852600 YP_001652632.1 CDS glnQ NC_010278.1 1794585 1795334 R polar amino acid ABC transporter ATPase complement(1794585..1795334) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852608 YP_001652633.1 CDS artM2 NC_010278.1 1795356 1796009 R amino acid ABC transporter permease complement(1795356..1796009) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852374 YP_001652634.1 CDS APJL_1638 NC_010278.1 1796222 1797520 R hypothetical protein complement(1796222..1797520) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852724 YP_001652635.1 CDS APJL_1639 NC_010278.1 1797792 1798286 D regulator of cell morphogenesis and NO signaling 1797792..1798286 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852141 YP_001652636.1 CDS APJL_1640 NC_010278.1 1798365 1798694 R drug resistance protein complement(1798365..1798694) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852815 YP_001652637.1 CDS APJL_1641 NC_010278.1 1798783 1799073 R hypothetical protein complement(1798783..1799073) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852798 YP_001652638.1 CDS APJL_1642 NC_010278.1 1799227 1799859 R hypothetical protein complement(1799227..1799859) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852799 YP_001652639.1 CDS APJL_1643 NC_010278.1 1800032 1800325 R hypothetical protein complement(1800032..1800325) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852816 YP_001652640.1 CDS ureH NC_010278.1 1800341 1801153 R urease accessory protein UreH complement(1800341..1801153) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852822 YP_001652641.1 CDS ureG NC_010278.1 1801322 1801957 R urease accessory protein UreG complement(1801322..1801957) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852801 YP_001652642.1 CDS ureF NC_010278.1 1801978 1802661 R urease accessory protein UreF complement(1801978..1802661) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852857 YP_001652643.1 CDS ureE NC_010278.1 1802673 1803251 R involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE complement(1802673..1803251) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852813 YP_001652644.1 CDS ureX NC_010278.1 1803367 1803984 R UreX complement(1803367..1803984) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852075 YP_001652645.1 CDS ureC NC_010278.1 1804108 1805826 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(1804108..1805826) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852076 YP_001652646.1 CDS ureB NC_010278.1 1805837 1806142 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta complement(1805837..1806142) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852852 YP_001652647.1 CDS ureA NC_010278.1 1806332 1806634 R UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma complement(1806332..1806634) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851806 YP_001652648.1 CDS utp NC_010278.1 1806706 1807608 R urea transport protein complement(1806706..1807608) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852835 YP_001652649.1 CDS cbiO NC_010278.1 1807646 1808275 R cobalt ABC transporter ATPase complement(1807646..1808275) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852838 YP_001652650.1 CDS cbiQ NC_010278.1 1808298 1808915 R cobalt ABC transporter permease CbiQ complement(1808298..1808915) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852837 YP_001652651.1 CDS cbiM NC_010278.1 1808922 1809530 R catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM complement(1808922..1809530) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852849 YP_001652652.1 CDS cbiL NC_010278.1 1809531 1810013 R putative cytoplasmic membrane protein CbiL complement(1809531..1810013) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851726 YP_001652653.1 CDS APJL_1657 NC_010278.1 1810013 1810699 R hypothetical protein complement(1810013..1810699) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852843 YP_001652654.1 CDS APJL_1658 NC_010278.1 1811042 1811797 D putative LysR-type transcriptional regulator 1811042..1811797 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852844 YP_001652655.1 CDS APJL_1659 NC_010278.1 1811876 1812337 R hypothetical protein complement(1811876..1812337) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851154 YP_001652656.1 CDS APJL_1660 NC_010278.1 1812565 1814430 R di- and tricarboxylate transporter complement(1812565..1814430) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850883 YP_001652657.1 CDS mtlR NC_010278.1 1814491 1815015 R Acts as a repressor of the mtlAD operon; mannitol repressor protein complement(1814491..1815015) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852851 YP_001652658.1 CDS mtlD NC_010278.1 1815015 1816154 R mannitol-1-phosphate 5-dehydrogenase complement(1815015..1816154) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851216 YP_001652659.1 CDS mtlA NC_010278.1 1816241 1818142 R phosphotransferase system, mannitol-specific IIBC component complement(1816241..1818142) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850721 YP_001652660.1 CDS glmS NC_010278.1 1818451 1820283 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(1818451..1820283) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850730 YP_001652661.1 CDS APJL_1665 NC_010278.1 1820407 1821165 R glucitol operon repressor complement(1820407..1821165) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850736 YP_001652662.1 CDS APJL_1666 NC_010278.1 1821303 1821503 R hypothetical protein complement(1821303..1821503) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850798 YP_001652663.1 CDS APJL_1667 NC_010278.1 1821602 1822594 R glycosyltransferase complement(1821602..1822594) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850746 YP_001652664.1 CDS APJL_1668 NC_010278.1 1822643 1824505 R O-linked N-acetylglucosaminetransferase complement(1822643..1824505) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850753 YP_001652665.1 CDS rimO NC_010278.1 1824521 1825852 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(1824521..1825852) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850763 YP_001652666.1 CDS mtn NC_010278.1 1826025 1826723 R MTA/SAH nucleosidase complement(1826025..1826723) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850764 YP_001652667.1 CDS APJL_1671 NC_010278.1 1826723 1827430 R thiol-disulfide isomerase and thioredoxin complement(1826723..1827430) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850781 YP_001652668.1 CDS APJL_1672 NC_010278.1 1827497 1827718 R hypothetical protein complement(1827497..1827718) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850782 YP_001652669.1 CDS fkpA1 NC_010278.1 1827809 1828528 D FKBP-type peptidyl-prolyl cis-trans isomerase 1827809..1828528 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850789 YP_001652670.1 CDS APJL_1674 NC_010278.1 1828640 1829299 D hypothetical protein 1828640..1829299 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850800 YP_001652671.1 CDS APJL_1675 NC_010278.1 1829299 1829676 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 1829299..1829676 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850806 YP_001652672.1 CDS APJL_1676 NC_010278.1 1829679 1830050 D hypothetical protein 1829679..1830050 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851102 YP_001652673.1 CDS APJL_1677 NC_010278.1 1830063 1830332 D hypothetical protein 1830063..1830332 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850808 YP_001652674.1 CDS atpC NC_010278.1 1836330 1836749 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1836330..1836749) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851208 YP_001652675.1 CDS atpD NC_010278.1 1836789 1838162 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1836789..1838162) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850877 YP_001652676.1 CDS atpG NC_010278.1 1838176 1839042 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1838176..1839042) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852826 YP_001652677.1 CDS atpA NC_010278.1 1839065 1840606 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1839065..1840606) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850894 YP_001652678.1 CDS atpH NC_010278.1 1840619 1841152 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1840619..1841152) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850906 YP_001652679.1 CDS atpF NC_010278.1 1841166 1841636 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1841166..1841636) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851207 YP_001652680.1 CDS atpE NC_010278.1 1841696 1841950 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1841696..1841950) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850908 YP_001652681.1 CDS atpB NC_010278.1 1842069 1842857 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(1842069..1842857) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850913 YP_001652682.1 CDS atpI NC_010278.1 1842882 1843265 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(1842882..1843265) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850914 YP_001652683.1 CDS gidB NC_010278.1 1843626 1844243 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(1843626..1844243) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851079 YP_001652684.1 CDS gidA NC_010278.1 1844343 1846235 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(1844343..1846235) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850915 YP_001652685.1 CDS cof NC_010278.1 1846706 1847497 D HAD superfamily hydrolase 1846706..1847497 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850922 YP_001652686.1 CDS APJL_1690 NC_010278.1 1847547 1848329 R amino acid ABC transporter substrate-binding protein complement(1847547..1848329) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851150 YP_001652687.1 CDS APJL_1691 NC_010278.1 1848541 1849017 R hypothetical protein complement(1848541..1849017) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850932 YP_001652688.1 CDS APJL_1692 NC_010278.1 1849020 1849397 R hypothetical protein complement(1849020..1849397) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851097 YP_001652689.1 CDS APJL_1693 NC_010278.1 1849485 1850312 R PTS system mannose-specific transporter subunit IID complement(1849485..1850312) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850937 YP_001652690.1 CDS APJL_1694 NC_010278.1 1850323 1851117 R PTS system mannose-specific transporter subunit IIC complement(1850323..1851117) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850939 YP_001652691.1 CDS APJL_1695 NC_010278.1 1851132 1852100 R phosphotransferase system,mannose/fructose/N-acetylgalactosamine-specific component IIB complement(1851132..1852100) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851086 YP_001652692.1 CDS gntP NC_010278.1 1852290 1853639 R gluconate permease complement(1852290..1853639) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850942 YP_001652693.1 CDS gntK NC_010278.1 1853817 1854332 D gluconate kinase 1853817..1854332 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850953 YP_001652694.1 CDS purR2 NC_010278.1 1854404 1855504 R transcriptional regulator complement(1854404..1855504) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850970 YP_001652695.1 CDS rbsR NC_010278.1 1855540 1856529 D ribose operon repressor 1855540..1856529 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850975 YP_001652696.1 CDS rbsD NC_010278.1 1856650 1857069 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 1856650..1857069 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850986 YP_001652697.1 CDS rbsA NC_010278.1 1857082 1858563 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 1857082..1858563 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850988 YP_001652698.1 CDS rbsC NC_010278.1 1858616 1859575 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 1858616..1859575 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850807 YP_001652699.1 CDS rbsB2 NC_010278.1 1859599 1860471 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 1859599..1860471 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850997 YP_001652700.1 CDS rbsK2 NC_010278.1 1860544 1861455 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 1860544..1861455 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851015 YP_001652701.1 CDS dmsA NC_010278.1 1861690 1864107 D anaerobic dimethyl sulfoxide reductase subunit A 1861690..1864107 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851276 YP_001652702.1 CDS dmsB NC_010278.1 1864117 1864734 D anaerobic dimethyl sulfoxide reductase subunit B 1864117..1864734 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851016 YP_001652703.1 CDS dmsC NC_010278.1 1864736 1865569 D anaerobic dimethyl sulfoxide reductase subunit C 1864736..1865569 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851028 YP_001652704.1 CDS APJL_1708 NC_010278.1 1865625 1866230 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1865625..1866230 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851031 YP_001652705.1 CDS APJL_1709 NC_010278.1 1866234 1866752 D ferredoxin 1866234..1866752 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851047 YP_001652706.1 CDS APJL_1710 NC_010278.1 1866749 1867378 R hypothetical protein complement(1866749..1867378) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851060 YP_001652707.1 CDS APJL_1711 NC_010278.1 1867660 1868151 D Abi family protein 1867660..1868151 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851062 YP_001652708.1 CDS APJL_1712 NC_010278.1 1868238 1868678 D abortive infection bacteriophage resistance protein 1868238..1868678 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851065 YP_001652709.1 CDS APJL_1713 NC_010278.1 1868834 1869475 R hypothetical protein complement(1868834..1869475) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850726 YP_001652710.1 CDS purL NC_010278.1 1869532 1873428 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(1869532..1873428) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851078 YP_001652711.1 CDS fucR NC_010278.1 1873655 1874401 D L-fucose operon activator 1873655..1874401 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850735 YP_001652712.1 CDS fucI NC_010278.1 1874623 1876389 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 1874623..1876389 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851092 YP_001652713.1 CDS fucK NC_010278.1 1876466 1877899 D L-fuculokinase 1876466..1877899 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851093 YP_001652714.1 CDS fucU NC_010278.1 1878034 1878468 D fucose operon FucU protein 1878034..1878468 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851113 YP_001652715.1 CDS fucA NC_010278.1 1878519 1879169 D catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 1878519..1879169 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851115 YP_001652716.1 CDS fucP NC_010278.1 1879223 1880512 D L-fucose permease 1879223..1880512 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851110 YP_001652717.1 CDS fucO NC_010278.1 1880632 1881783 D L-1,2-propanediol oxidoreductase 1880632..1881783 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851118 YP_001652718.1 CDS APJL_1722 NC_010278.1 1881986 1882627 D periplasmic/secreted protein 1881986..1882627 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851257 YP_001652719.1 CDS APJL_1723 NC_010278.1 1882829 1883488 D ABC transporter permease 1882829..1883488 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851128 YP_001652720.1 CDS APJL_1724 NC_010278.1 1883478 1884146 D ABC transporter permease 1883478..1884146 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851130 YP_001652721.1 CDS APJL_1725 NC_010278.1 1884147 1884878 D ABC transporter ATP-binding protein 1884147..1884878 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850773 YP_001652722.1 CDS APJL_1726 NC_010278.1 1884939 1885775 D putative ABC transporter periplasmic binding protein 1884939..1885775 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851137 YP_001652723.1 CDS lipA2 NC_010278.1 1885908 1887977 D capsule polysaccharide modification protein 1885908..1887977 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851151 YP_001652724.1 CDS phyB NC_010278.1 1888000 1889220 D PhyB, capsule biosynthetic locus protein 1888000..1889220 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851165 YP_001652725.1 CDS APJL_1729 NC_010278.1 1889289 1890317 R hypothetical protein complement(1889289..1890317) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851172 YP_001652726.1 CDS ulaD NC_010278.1 1890412 1891092 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(1890412..1891092) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851139 YP_001652727.1 CDS APJL_1731 NC_010278.1 1891163 1891630 R PTS system enzyme II-A permease complement(1891163..1891630) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851385 YP_001652728.1 CDS sgaT NC_010278.1 1891708 1893489 R PTS system ascorbate-specific transporter subunits IICB complement(1891708..1893489) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851801 YP_001652729.1 CDS ulaG NC_010278.1 1893989 1895080 D putative L-ascorbate 6-phosphate lactonase 1893989..1895080 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851089 YP_001652730.1 CDS APJL_1734 NC_010278.1 1895182 1895928 D negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 1895182..1895928 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851237 YP_001652731.1 CDS sgbU NC_010278.1 1896014 1896874 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 1896014..1896874 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850848 YP_001652732.1 CDS araD NC_010278.1 1896868 1897581 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 1896868..1897581 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851255 YP_001652733.1 CDS fkpA2 NC_010278.1 1897758 1898363 R FKBP-type peptidyl-prolyl cis-trans isomerase 1 complement(1897758..1898363) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851259 YP_001652734.1 CDS APJL_1738 NC_010278.1 1898690 1899427 D hypothetical protein 1898690..1899427 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850787 YP_001652735.1 CDS APJL_1739 NC_010278.1 1899568 1900017 R hypothetical protein complement(1899568..1900017) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851266 YP_001652736.1 CDS tolA2 NC_010278.1 1900117 1901466 D colicin import membrane protein 1900117..1901466 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851210 YP_001652737.1 CDS APJL_1741 NC_010278.1 1901613 1903019 D hypothetical protein 1901613..1903019 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851270 YP_001652738.1 CDS rfaD NC_010278.1 1903080 1904006 R catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase complement(1903080..1904006) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850780 YP_001652739.1 CDS def NC_010278.1 1904146 1904610 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1904146..1904610) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851201 YP_001652740.1 CDS smf NC_010278.1 1904844 1905998 D Smf protein 1904844..1905998 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851284 YP_001652741.1 CDS APJL_1745 NC_010278.1 1906042 1908048 R putative oligopeptide transporter complement(1906042..1908048) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850929 YP_001652742.1 CDS APJL_1746 NC_010278.1 1908160 1908261 D hypothetical protein 1908160..1908261 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851286 YP_001652743.1 CDS ulaA NC_010278.1 1908269 1909624 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(1908269..1909624) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851291 YP_001652744.1 CDS sgaB NC_010278.1 1909633 1909905 R phosphotransferase system, galactitol-specific IIB component complement(1909633..1909905) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850829 YP_001652745.1 CDS secE NC_010278.1 1910208 1910621 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1910208..1910621 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851292 YP_001652746.1 CDS nusG NC_010278.1 1910656 1911186 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1910656..1911186 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850854 YP_001652747.2 CDS rplK NC_010278.1 <1911528 1911902 D truncated; 50S ribosomal protein L11 <1911528..1911902 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851299 YP_001652748.1 CDS rplA NC_010278.1 1911907 1912596 D 50S ribosomal protein L1 1911907..1912596 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851312 YP_001652749.1 CDS rplL NC_010278.1 1913437 1913805 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1913437..1913805 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850955 YP_001652750.1 CDS APJL_1756 NC_010278.1 1913969 1914241 D hypothetical protein 1913969..1914241 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851316 YP_001652751.1 CDS APJL_1757 NC_010278.1 1914246 1915502 D hypothetical protein 1914246..1915502 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851568 YP_001652752.1 CDS APJL_1758 NC_010278.1 1915660 1915878 D hypothetical protein 1915660..1915878 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851580 YP_001652753.1 CDS APJL_1759 NC_010278.1 1915889 1916428 D hypothetical protein 1915889..1916428 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851355 YP_001652754.1 CDS APJL_1760 NC_010278.1 1916503 1916817 D hypothetical protein 1916503..1916817 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851585 YP_001652755.1 CDS APJL_1761 NC_010278.1 1916914 1917699 D hypothetical protein 1916914..1917699 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852035 YP_001652756.1 CDS rpoB NC_010278.1 1918000 1922028 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1918000..1922028 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850867 YP_001652757.1 CDS rpoC NC_010278.1 1922154 1926425 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1922154..1926425 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850976 YP_001652758.1 CDS APJL_1764 NC_010278.1 1926587 1928002 D hypothetical protein 1926587..1928002 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851858 YP_001652759.1 CDS APJL_1765 NC_010278.1 1927995 1928567 D hypothetical protein 1927995..1928567 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851170 YP_001652760.1 CDS APJL_1766 NC_010278.1 1929188 1929418 D hypothetical protein 1929188..1929418 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850951 YP_001652761.1 CDS APJL_1767 NC_010278.1 1929418 1929816 D nucleic acid-binding protein 1929418..1929816 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851964 YP_001652762.1 CDS APJL_1768 NC_010278.1 1929952 1930368 R hypothetical protein complement(1929952..1930368) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851203 YP_001652763.1 CDS APJL_1769 NC_010278.1 1930614 1931264 D hypothetical protein 1930614..1931264 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851565 YP_001652764.1 CDS APJL_1770 NC_010278.1 1931337 1931996 R hypothetical protein complement(1931337..1931996) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850788 YP_001652765.1 CDS hslU NC_010278.1 1932310 1933632 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(1932310..1933632) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851244 YP_001652766.1 CDS hslV NC_010278.1 1933898 1934419 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(1933898..1934419) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851960 YP_001652767.1 CDS sfsA NC_010278.1 1934497 1935210 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(1934497..1935210) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851460 YP_001652768.1 CDS gloA2 NC_010278.1 1935517 1935909 R lactoylglutathione lyase complement(1935517..1935909) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851467 YP_001652769.1 CDS mutY NC_010278.1 1936009 1937154 D A/G-specific adenine glycosylase 1936009..1937154 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851398 YP_001652770.1 CDS APJL_1776 NC_010278.1 1937158 1937433 D hypothetical protein 1937158..1937433 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851138 YP_001652771.1 CDS mltC NC_010278.1 1937451 1938548 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 1937451..1938548 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851305 YP_001652772.1 CDS ffh NC_010278.1 1939542 1940933 D signal recognition particle GTPase 1939542..1940933 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851424 YP_001652773.1 CDS APJL_1779 NC_010278.1 1941087 1942751 R 2',3'-cyclic-nucleotide 2'-phosphodiesterase complement(1941087..1942751) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851426 YP_001652774.1 CDS ubiF NC_010278.1 1942943 1944109 R 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase complement(1942943..1944109) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851536 YP_001652775.1 CDS APJL_1781 NC_010278.1 1944143 1944451 R transcriptional regulator complement(1944143..1944451) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851425 YP_001652776.1 CDS comM NC_010278.1 1944783 1946309 D competence protein M 1944783..1946309 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851391 YP_001652777.1 CDS APJL_1783 NC_010278.1 1946432 1947526 D outer membrane lipoprotein A 1946432..1947526 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851464 YP_001652778.1 CDS APJL_1784 NC_010278.1 1947577 1948341 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(1947577..1948341) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851875 YP_001652779.1 CDS menD NC_010278.1 1948341 1950047 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(1948341..1950047) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851934 YP_001652780.1 CDS neuA NC_010278.1 1950300 1950893 D acylneuraminate cytidylyltransferase 1950300..1950893 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851793 YP_001652781.1 CDS nanE NC_010278.1 1950931 1951620 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1950931..1951620 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851563 YP_001652782.1 CDS APJL_1788 NC_010278.1 1951630 1952502 D catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 1951630..1952502 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851336 YP_001652783.1 CDS nanA NC_010278.1 1952523 1953401 D catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 1952523..1953401 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851538 YP_001652784.1 CDS nagB NC_010278.1 1953451 1954254 D catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 1953451..1954254 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851439 YP_001652785.1 CDS nagA NC_010278.1 1954306 1955451 D catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 1954306..1955451 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850832 YP_001652786.1 CDS fumC NC_010278.1 1955600 1956994 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1955600..1956994) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851567 YP_001652787.1 CDS APJL_1793 NC_010278.1 1957149 1957805 R DNA transformation protein complement(1957149..1957805) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851332 YP_001652788.1 CDS rpsJ NC_010278.1 1958213 1958524 D 30S ribosomal protein S10 1958213..1958524 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851449 YP_001652789.1 CDS rplC NC_010278.1 1958550 1959176 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1958550..1959176 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851386 YP_001652790.1 CDS rplD NC_010278.1 1959192 1959794 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1959192..1959794 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851224 YP_001652791.1 CDS rplW NC_010278.1 1959791 1960096 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1959791..1960096 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851394 YP_001652792.1 CDS rplB NC_010278.1 1960117 1960938 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1960117..1960938 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851543 YP_001652793.1 CDS rpsS NC_010278.1 1960966 1961241 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1960966..1961241 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851461 YP_001652794.1 CDS rplV NC_010278.1 1961252 1961584 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1961252..1961584 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851810 YP_001652795.1 CDS rpsC NC_010278.1 1961603 1962310 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1961603..1962310 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851974 YP_001652796.1 CDS rplP NC_010278.1 1962324 1962734 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1962324..1962734 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851116 YP_001652797.1 CDS rpmC NC_010278.1 1962734 1962925 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1962734..1962925 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851452 YP_001652798.1 CDS rpsQ NC_010278.1 1962925 1963179 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1962925..1963179 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851982 YP_001652799.1 CDS rplN NC_010278.1 1963419 1963790 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1963419..1963790 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851132 YP_001652800.1 CDS rplX NC_010278.1 1963801 1964112 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1963801..1964112 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851408 YP_001652801.1 CDS rplE NC_010278.1 1964130 1964669 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1964130..1964669 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851716 YP_001652802.1 CDS rpsN NC_010278.1 1964681 1964986 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1964681..1964986 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851418 YP_001652803.1 CDS rpsH NC_010278.1 1965023 1965415 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1965023..1965415 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850947 YP_001652804.1 CDS rplF NC_010278.1 1965432 1965965 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1965432..1965965 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850838 YP_001652805.1 CDS rplR NC_010278.1 1965980 1966333 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1965980..1966333 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851396 YP_001652806.1 CDS rpsE NC_010278.1 1966348 1966848 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1966348..1966848 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851603 YP_001652807.1 CDS rpmD NC_010278.1 1966855 1967034 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1966855..1967034 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851182 YP_001652808.1 CDS rplO NC_010278.1 1967039 1967473 D late assembly protein; 50S ribosomal protein L15 1967039..1967473 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850729 YP_001652809.1 CDS secY NC_010278.1 1967477 1968799 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1967477..1968799 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850895 YP_001652810.1 CDS rpmJ NC_010278.1 1968825 1968938 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1968825..1968938 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850812 YP_001652811.1 CDS rpsM NC_010278.1 1969075 1969431 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1969075..1969431 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851731 YP_001652812.1 CDS rpsK NC_010278.1 1969448 1969837 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1969448..1969837 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851297 YP_001652813.1 CDS rpsD NC_010278.1 1969866 1970492 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1969866..1970492 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851044 YP_001652814.1 CDS rpoA NC_010278.1 1970558 1971547 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1970558..1971547 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851099 YP_001652815.1 CDS rplQ NC_010278.1 1971583 1971966 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1971583..1971966 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851724 YP_001652816.1 CDS rpsP NC_010278.1 1972203 1972451 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1972203..1972451 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851410 YP_001652817.1 CDS rimM NC_010278.1 1972485 1973012 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1972485..1973012 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851663 YP_001652818.1 CDS trmD NC_010278.1 1973070 1973825 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1973070..1973825 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851330 YP_001652819.1 CDS rplS NC_010278.1 1973851 1974201 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1973851..1974201 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851454 YP_001652820.1 CDS APJL_1826 NC_010278.1 1974371 1975564 R hypothetical protein complement(1974371..1975564) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851455 YP_001652821.1 CDS APJL_1827 NC_010278.1 1975780 1976895 D Fe3+-hydroxamate ABC transporter,periplasmic protein 1975780..1976895 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851463 YP_001652822.1 CDS APJL_1828 NC_010278.1 1976898 1977935 D Fe(III) dicitrate ABC transporter permease 1976898..1977935 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851347 YP_001652823.1 CDS hmuV NC_010278.1 1977951 1978718 D hemin import ATP-binding protein 1977951..1978718 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851534 YP_001652824.1 CDS APJL_1830 NC_010278.1 1978728 1979159 D plastocyanin 1978728..1979159 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851625 YP_001652825.1 CDS APJL_1831 NC_010278.1 1979168 1980274 D Fe3+-hydroxamate ABC transporter,periplasmic protein 1979168..1980274 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851769 YP_001652826.1 CDS APJL_1832 NC_010278.1 1980330 1981181 D hypothetical protein 1980330..1981181 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851787 YP_001652827.1 CDS torD NC_010278.1 1981224 1981823 R TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD complement(1981224..1981823) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850775 YP_001652828.1 CDS torA NC_010278.1 1981823 1984306 R trimethylamine-n-oxide reductase complement(1981823..1984306) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851737 YP_001652829.1 CDS torC2 NC_010278.1 1984316 1984936 R cytochrome c-type protein complement(1984316..1984936) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851710 YP_001652830.1 CDS glyQ NC_010278.1 1985130 1986044 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1985130..1986044 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851805 YP_001652831.1 CDS APJL_1837 NC_010278.1 1986087 1986470 D hypothetical protein 1986087..1986470 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851695 YP_001652832.1 CDS APJL_1838 NC_010278.1 1986943 1987347 D hypothetical protein 1986943..1987347 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851349 YP_001652833.1 CDS glyS NC_010278.1 1987385 1989454 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1987385..1989454 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850824 YP_001652834.1 CDS APJL_1840 NC_010278.1 1989570 1989860 D hypothetical protein 1989570..1989860 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851217 YP_001652835.1 CDS xerC NC_010278.1 1989861 1990871 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1989861..1990871 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851215 YP_001652836.1 CDS APJL_1842 NC_010278.1 1990875 1991264 R hypothetical protein complement(1990875..1991264) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851234 YP_001652837.1 CDS APJL_1843 NC_010278.1 1991328 1992074 R hypothetical protein complement(1991328..1992074) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851438 YP_001652838.1 CDS lpxH NC_010278.1 1992116 1992847 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(1992116..1992847) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850855 YP_001652839.1 CDS APJL_1845 NC_010278.1 1992880 1993404 R hypothetical protein complement(1992880..1993404) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850755 YP_001652840.1 CDS APJL_1846 NC_010278.1 1993439 1994227 R putative deoxyribonuclease complement(1993439..1994227) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851014 YP_001652841.1 CDS APJL_1847 NC_010278.1 1994432 1994635 R hypothetical protein complement(1994432..1994635) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851162 YP_001652842.1 CDS APJL_1848 NC_010278.1 1995317 1995949 D hypothetical protein 1995317..1995949 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850945 YP_001652843.1 CDS APJL_1849 NC_010278.1 1996055 1997995 R ABC transporter ATP-binding protein complement(1996055..1997995) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851133 YP_001652844.1 CDS APJL_1850 NC_010278.1 1997995 1999158 R hypothetical protein complement(1997995..1999158) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851481 YP_001652845.1 CDS APJL_1851 NC_010278.1 1999291 2000067 R putative outer membrane protein complement(1999291..2000067) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850792 YP_001652846.1 CDS holB NC_010278.1 2000398 2001381 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(2000398..2001381) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850923 YP_001652847.1 CDS tmk NC_010278.1 2001384 2002010 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(2001384..2002010) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851444 YP_001652848.1 CDS APJL_1854 NC_010278.1 2002014 2003048 R periplasmic solute-binding protein complement(2002014..2003048) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851403 YP_001652849.1 CDS acpP NC_010278.1 2003646 2003951 R acyl carrier protein complement(2003646..2003951) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851539 YP_001652850.1 CDS rpe NC_010278.1 2004143 2004817 R D-ribulose-phosphate-3 epimerase complement(2004143..2004817) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851630 YP_001652851.1 CDS rpmE2 NC_010278.1 2005039 2005308 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 2005039..2005308 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851618 YP_001652852.1 CDS rpmJ NC_010278.1 2005322 2005447 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 2005322..2005447 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851174 YP_001652853.1 CDS ponB NC_010278.1 2005552 2007954 R penicillin-binding protein 1B complement(2005552..2007954) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851145 YP_001652854.1 CDS menB NC_010278.1 2008033 2008890 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2008033..2008890) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850924 YP_001652855.1 CDS spoT NC_010278.1 2009025 2010731 R guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase complement(2009025..2010731) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851191 YP_001652856.1 CDS rpoZ NC_010278.1 2010827 2011108 R promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(2010827..2011108) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851195 YP_001652857.1 CDS recG NC_010278.1 2011235 2013316 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(2011235..2013316) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851564 YP_001652858.1 CDS APJL_1864 NC_010278.1 2013440 2013868 R PilT protein-like protein complement(2013440..2013868) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851241 YP_001652859.1 CDS APJL_1865 NC_010278.1 2013868 2014155 R hypothetical protein complement(2013868..2014155) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851107 YP_001652860.1 CDS APJL_1866 NC_010278.1 2014225 2014320 D hypothetical protein 2014225..2014320 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851962 YP_001652861.1 CDS proS NC_010278.1 2014361 2016076 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 2014361..2016076 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850965 YP_001652862.1 CDS APJL_1868 NC_010278.1 2016142 2016330 R hypothetical protein complement(2016142..2016330) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851470 YP_001652863.1 CDS APJL_1869 NC_010278.1 2016333 2016914 R Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor complement(2016333..2016914) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851400 YP_001652864.1 CDS APJL_1870 NC_010278.1 2017003 2017959 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 2017003..2017959 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850712 YP_001652865.1 CDS APJL_1871 NC_010278.1 2017959 2018552 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 2017959..2018552 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850898 YP_001652866.1 CDS rpoH NC_010278.1 2018663 2019613 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(2018663..2019613) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850983 YP_001652867.1 CDS APJL_1873 NC_010278.1 2019762 2021099 R sugar phosphate permease complement(2019762..2021099) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851608 YP_001652868.1 CDS APJL_1874 NC_010278.1 2021674 2022249 D hypothetical protein 2021674..2022249 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851544 YP_001652869.1 CDS APJL_1875 NC_010278.1 2022269 2022661 D hypothetical protein 2022269..2022661 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851465 YP_001652870.1 CDS asnA NC_010278.1 2022704 2023696 R catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA complement(2022704..2023696) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851450 YP_001652871.1 CDS asnC NC_010278.1 2023878 2024339 D transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 2023878..2024339 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851556 YP_001652872.1 CDS udp NC_010278.1 2024528 2025292 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 2024528..2025292 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851114 YP_001652873.1 CDS ubiC NC_010278.1 2025356 2025850 D 4-hydroxybenzoate synthetase/chorismate--pyruvate lyase 2025356..2025850 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851441 YP_001652874.1 CDS murI NC_010278.1 2025923 2026720 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 2025923..2026720 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850776 YP_001652875.1 CDS cysI NC_010278.1 2033112 2034878 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(2033112..2034878) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851546 YP_001652876.1 CDS cysJ NC_010278.1 2034906 2036717 R sulfite reductase (NADPH) flavoprotein alpha-component complement(2034906..2036717) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851542 YP_001652877.1 CDS cysN NC_010278.1 2037018 2038310 R sulfate adenylyltransferase complement(2037018..2038310) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851462 YP_001652878.1 CDS cysD NC_010278.1 2038393 2039319 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(2038393..2039319) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851411 YP_001652879.1 CDS cysH NC_010278.1 2039334 2040068 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(2039334..2040068) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851958 YP_001652880.1 CDS cysG NC_010278.1 2040082 2041542 R uroporphyrinogen-III methylase complement(2040082..2041542) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851879 YP_001652881.1 CDS sbp NC_010278.1 2041817 2042809 D sulfate-binding protein 2041817..2042809 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851735 YP_001652882.1 CDS cysU NC_010278.1 2042828 2043640 D sulfate ABC transporter permease 2042828..2043640 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851891 YP_001652883.1 CDS cysW NC_010278.1 2043659 2044474 D sulfate ABC transporter permease 2043659..2044474 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851828 YP_001652884.1 CDS cysA NC_010278.1 2044485 2045555 D ABC-type sulfate/molybdate transport systems, ATPase component 2044485..2045555 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851825 YP_001652885.1 CDS lldD NC_010278.1 2045644 2046789 R flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase complement(2045644..2046789) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851838 YP_001652886.1 CDS birA NC_010278.1 2046973 2047737 R biotin operon represssor complement(2046973..2047737) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851995 YP_001652887.1 CDS murB NC_010278.1 2047746 2048780 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(2047746..2048780) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851913 YP_001652888.1 CDS momP2 NC_010278.1 2048930 2050024 R major outer membrane protein complement(2048930..2050024) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851926 YP_001652889.1 CDS APJL_1895 NC_010278.1 2050442 2050951 D transposase and inactivated derivative 2050442..2050951 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851981 YP_001652890.1 CDS APJL_1896 NC_010278.1 2050963 2051775 D transposase 2050963..2051775 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851816 YP_001652891.1 CDS ilvC NC_010278.1 2051835 2053316 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(2051835..2053316) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852027 YP_001652892.1 CDS APJL_1898 NC_010278.1 2053553 2054794 D PqiA protein 2053553..2054794 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851876 YP_001652893.1 CDS APJL_1899 NC_010278.1 2054971 2056071 D hypothetical protein 2054971..2056071 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851835 YP_001652894.1 CDS APJL_1900 NC_010278.1 2056043 2056396 D putative mercuric transport protein 2056043..2056396 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852003 YP_001652895.1 CDS APJL_1901 NC_010278.1 2056393 2056707 D copper chaperone 2056393..2056707 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851997 YP_001652896.1 CDS APJL_1902 NC_010278.1 2056830 2058014 R NADH-dependent butanol dehydrogenase 1 complement(2056830..2058014) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851890 YP_001652897.1 CDS APJL_1903 NC_010278.1 2058130 2059032 D transcriptional regulator 2058130..2059032 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851851 YP_001652898.1 CDS dapD NC_010278.1 2059236 2060060 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 2059236..2060060 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852850 YP_001652899.1 CDS aroQ NC_010278.1 2060125 2060589 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 2060125..2060589 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852036 YP_001652900.1 CDS APJL_1906 NC_010278.1 2060582 2061370 D glycosyltransferase 2060582..2061370 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852066 YP_001652901.1 CDS accB NC_010278.1 2061542 2062006 D biotin carboxyl carrier protein ofacetyl-CoA carboxylase 2061542..2062006 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852045 YP_001652902.1 CDS accC NC_010278.1 2062162 2063505 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 2062162..2063505 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852052 YP_001652903.1 CDS mobAB NC_010278.1 2063548 2064639 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; MobB is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB complement(2063548..2064639) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852054 YP_001652904.1 CDS APJL_1910 NC_010278.1 2064726 2064995 D hypothetical protein 2064726..2064995 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852059 YP_001652905.1 CDS dsbA NC_010278.1 2065039 2065677 D thiol:disulfide interchange protein 2065039..2065677 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852086 YP_001652906.1 CDS APJL_1912 NC_010278.1 2065769 2066035 R hypothetical protein complement(2065769..2066035) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852097 YP_001652907.1 CDS APJL_1913 NC_010278.1 2066148 2066354 R hypothetical protein complement(2066148..2066354) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852081 YP_001652908.1 CDS APJL_1914 NC_010278.1 2066457 2067380 R cell division protein complement(2066457..2067380) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852087 YP_001652909.1 CDS APJL_1915 NC_010278.1 2067492 2068247 R hypothetical protein complement(2067492..2068247) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852098 YP_001652910.1 CDS APJL_1916 NC_010278.1 2068265 2068933 R D-alanyl-D-alanine carboxypeptidase complement(2068265..2068933) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852793 YP_001652911.1 CDS dapE NC_010278.1 2068952 2070085 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(2068952..2070085) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852112 YP_001652912.1 CDS APJL_1918 NC_010278.1 2070108 2070458 R hypothetical protein complement(2070108..2070458) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852113 YP_001652913.1 CDS APJL_1919 NC_010278.1 2070665 2071375 D hypothetical protein 2070665..2071375 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852094 YP_001652914.1 CDS folP NC_010278.1 2071426 2072271 R dihydropteroate synthase complement(2071426..2072271) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852750 YP_001652915.1 CDS rluC NC_010278.1 2072333 2073298 R catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C complement(2072333..2073298) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852227 YP_001652916.1 CDS APJL_1922 NC_010278.1 2073451 2076009 D outer membrane receptor protein, mostly Fe transport 2073451..2076009 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852350 YP_001652917.1 CDS APJL_1923 NC_010278.1 2076165 2077076 D small-conductance mechanosensitive channel 2076165..2077076 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852127 YP_001652918.1 CDS APJL_1924 NC_010278.1 2077272 2078450 D carbamoylphosphate synthase large subunit 2077272..2078450 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852593 YP_001652919.1 CDS APJL_1925 NC_010278.1 2078462 2079214 D hypothetical protein 2078462..2079214 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852153 YP_001652920.1 CDS ptrA NC_010278.1 2079282 2082242 R protease III complement(2079282..2082242) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852271 YP_001652921.1 CDS recC NC_010278.1 2082239 2085583 R exodeoxyribonuclease V subunit gamma complement(2082239..2085583) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852122 YP_001652922.1 CDS APJL_1928 NC_010278.1 2085688 2085984 R hypothetical protein complement(2085688..2085984) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852129 YP_001652923.1 CDS APJL_1929 NC_010278.1 2085974 2086630 R hypothetical protein complement(2085974..2086630) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852143 YP_001652924.1 CDS APJL_1930 NC_010278.1 2086640 2087338 R hypothetical protein complement(2086640..2087338) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852219 YP_001652925.1 CDS APJL_1931 NC_010278.1 2087298 2087828 R hypothetical protein complement(2087298..2087828) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852522 YP_001652926.1 CDS fabA NC_010278.1 2087916 2088446 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(2087916..2088446) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852140 YP_001652927.1 CDS lonH NC_010278.1 2088557 2090194 R lon protease complement(2088557..2090194) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852149 YP_001652928.1 CDS APJL_1934 NC_010278.1 2090279 2090725 D hypothetical protein 2090279..2090725 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852136 YP_001652929.1 CDS trpS NC_010278.1 2090797 2091825 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(2090797..2091825) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852145 YP_001652930.1 CDS gph NC_010278.1 2091965 2092630 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(2091965..2092630) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852152 YP_001652931.1 CDS APJL_1937 NC_010278.1 2092800 2092991 R hypothetical protein complement(2092800..2092991) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852154 YP_001652932.1 CDS lgt NC_010278.1 2093189 2093983 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(2093189..2093983) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852183 YP_001652933.1 CDS APJL_1939 NC_010278.1 2094036 2094827 R permease complement(2094036..2094827) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852264 YP_001652934.1 CDS nudH NC_010278.1 2094824 2095444 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(2094824..2095444) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852319 YP_001652935.1 CDS APJL_1941 NC_010278.1 2095483 2095647 D hypothetical protein 2095483..2095647 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852332 YP_001652936.1 CDS APJL_1942 NC_010278.1 2095989 2096756 R Zn-dependent protease with chaperone function complement(2095989..2096756) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852409 YP_001652937.1 CDS ppa NC_010278.1 2096852 2097379 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(2096852..2097379) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852474 YP_001652938.1 CDS menG NC_010278.1 2098209 2098706 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(2098209..2098706) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852261 YP_001652939.1 CDS yrhG NC_010278.1 2099009 2099719 D putative formate-nitrite transporter 2099009..2099719 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852641 YP_001652940.1 CDS APJL_1948 NC_010278.1 2099890 2100714 D hypothetical protein 2099890..2100714 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852705 YP_001652941.1 CDS APJL_1949 NC_010278.1 2100862 2101674 R transposase complement(2100862..2101674) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852161 YP_001652942.1 CDS APJL_1950 NC_010278.1 2101686 2102195 R transposase and inactivated derivative complement(2101686..2102195) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852676 YP_001652943.1 CDS APJL_1951 NC_010278.1 2102188 2103042 R hypothetical protein complement(2102188..2103042) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852210 YP_001652944.1 CDS dnaJ NC_010278.1 2103301 2104443 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(2103301..2104443) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852738 YP_001652945.1 CDS dnaK NC_010278.1 2104582 2106483 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(2104582..2106483) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852606 YP_001652946.1 CDS xylB2 NC_010278.1 2106758 2108203 R sugar (pentulose and hexulose) kinase complement(2106758..2108203) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852818 YP_001652947.1 CDS xylA NC_010278.1 2108401 2109720 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(2108401..2109720) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852797 YP_001652948.1 CDS xylF NC_010278.1 2109974 2110972 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 2109974..2110972 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852790 YP_001652949.1 CDS xylG NC_010278.1 2111036 2112550 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 2111036..2112550 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851804 YP_001652950.1 CDS xylH NC_010278.1 2112554 2113681 D D-xylose transport system permease 2112554..2113681 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851938 YP_001652951.1 CDS purR3 NC_010278.1 2113806 2114987 D transcriptional regulator 2113806..2114987 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851741 YP_001652952.1 CDS pepO NC_010278.1 2114992 2117019 D metallopeptidase 2114992..2117019 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851766 YP_001652953.1 CDS APJL_1961 NC_010278.1 2117094 2117321 D hypothetical protein 2117094..2117321 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852078 YP_001652954.1 CDS panF NC_010278.1 2117390 2118802 R mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter complement(2117390..2118802) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851368 YP_001652955.1 CDS APJL_1963 NC_010278.1 2118822 2119046 R hypothetical protein complement(2118822..2119046) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851530 YP_001652956.1 CDS metJ NC_010278.1 2119098 2119415 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(2119098..2119415) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852309 YP_001652957.1 CDS vacJ NC_010278.1 2119584 2120333 D VacJ lipoprotein 2119584..2120333 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852034 YP_001652958.1 CDS APJL_1966 NC_010278.1 2120408 2121217 D hypothetical protein 2120408..2121217 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851445 YP_001652959.1 CDS APJL_1967 NC_010278.1 2121342 2123309 D site-specific recombinase 2121342..2123309 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851010 YP_001652960.1 CDS pgaA NC_010278.1 2124055 2126547 D biofilm PGA synthesis protein PgaA 2124055..2126547 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851378 YP_001652961.1 CDS pgaB NC_010278.1 2126562 2128334 D biofilm PGA synthesis lipoprotein PgaB 2126562..2128334 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850743 YP_001652962.1 CDS pgaC NC_010278.1 2128343 2129524 D predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 2128343..2129524 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850972 YP_001652963.1 CDS pgaD NC_010278.1 2129526 2129810 D FOG: WD40 repeat; biofilm PGA synthesis protein 2129526..2129810 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851322 YP_001652964.1 CDS tpiA NC_010278.1 2129914 2130684 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(2129914..2130684) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851232 YP_001652965.1 CDS truD NC_010278.1 2130959 2131972 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 2130959..2131972 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851549 YP_001652966.1 CDS surE NC_010278.1 2131972 2132736 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 2131972..2132736 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851272 YP_001652967.1 CDS APJL_1975 NC_010278.1 2132736 2133320 D hypothetical protein 2132736..2133320 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850861 YP_001652968.1 CDS APJL_1976 NC_010278.1 2133332 2133907 D lipoprotein 2133332..2133907 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851059 YP_001652969.1 CDS APJL_1977 NC_010278.1 2133993 2134190 D hypothetical protein 2133993..2134190 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850954 YP_001652970.1 CDS lppB NC_010278.1 2134266 2135462 D outer membrane antigenic lipoprotein B 2134266..2135462 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851473 YP_001652971.1 CDS tagI NC_010278.1 2135551 2136114 D DNA-3-methyladenine glycosidase I 2135551..2136114 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851283 YP_001652972.1 CDS APJL_1980 NC_010278.1 2136166 2137293 R carboxypeptidase G2 complement(2136166..2137293) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850865 YP_001652973.1 CDS APJL_1981 NC_010278.1 2137307 2137771 R hypothetical protein complement(2137307..2137771) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850936 YP_001652974.1 CDS APJL_1982 NC_010278.1 2137768 2138406 R hypothetical protein complement(2137768..2138406) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851497 YP_001652975.1 CDS hemH NC_010278.1 2138583 2139542 R protoheme ferro-lyase complement(2138583..2139542) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851505 YP_001652976.1 CDS rpmH NC_010278.1 2139818 2139952 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 2139818..2139952 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850724 YP_001652977.1 CDS rnpA NC_010278.1 2140018 2140350 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 2140018..2140350 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851504 YP_001652978.1 CDS APJL_1986 NC_010278.1 2140377 2140613 D hypothetical protein 2140377..2140613 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851126 YP_001652979.1 CDS glnA NC_010278.1 2140664 2142079 R glutamine synthetase complement(2140664..2142079) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851043 YP_001652980.1 CDS icc NC_010278.1 2142437 2143264 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(2142437..2143264) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851479 YP_001652981.1 CDS APJL_1989 NC_010278.1 2143471 2144094 R putative ADP-ribose pyrophosphatase complement(2143471..2144094) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851562 YP_001652982.1 CDS psiE2 NC_010278.1 2144104 2144523 R phosphate-starvation-inducible protein PsiE complement(2144104..2144523) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851629 YP_001652983.1 CDS APJL_1991 NC_010278.1 2144516 2145244 R putative 4'-phosphopantetheinyl transferase complement(2144516..2145244) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851345 YP_001652984.1 CDS APJL_1992 NC_010278.1 2145304 2145732 R integral membrane protein complement(2145304..2145732) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851120 YP_001652985.1 CDS APJL_1993 NC_010278.1 2145735 2145911 R hypothetical protein complement(2145735..2145911) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851380 YP_001652986.1 CDS nhaA NC_010278.1 2145910 2147094 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 2145910..2147094 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851631 YP_001652987.1 CDS APJL_1995 NC_010278.1 2147237 2147725 D hypothetical protein 2147237..2147725 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851159 YP_001652988.1 CDS dtd NC_010278.1 2147761 2148195 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(2147761..2148195) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851202 YP_001652989.1 CDS rbn NC_010278.1 2148192 2149022 R RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN complement(2148192..2149022) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851095 YP_001652990.1 CDS proA NC_010278.1 2149040 2150278 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(2149040..2150278) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850958 YP_001652991.1 CDS APJL_1999 NC_010278.1 2150479 2150658 D hypothetical protein 2150479..2150658 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851119 YP_001652992.1 CDS APJL_2003 NC_010278.1 2153027 2153881 R hypothetical protein complement(2153027..2153881) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851288 YP_001652993.1 CDS APJL_2004 NC_010278.1 2154000 2155244 R hypothetical protein complement(2154000..2155244) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851632 YP_001652994.1 CDS mutL NC_010278.1 2155558 2157426 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 2155558..2157426 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851001 YP_001652995.1 CDS adh3 NC_010278.1 2157626 2158675 D similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 2157626..2158675 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851551 YP_001652996.1 CDS miaA NC_010278.1 2158807 2159751 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 2158807..2159751 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851372 YP_001652997.1 CDS hfq NC_010278.1 2159816 2160094 D host factor-I protein Hfq 2159816..2160094 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850981 YP_001652998.1 CDS hflX NC_010278.1 2160426 2161499 D GTP-binding protein HflX 2160426..2161499 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851469 YP_001652999.1 CDS APJL_2010 NC_010278.1 2161535 2162095 R hypothetical protein complement(2161535..2162095) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851458 YP_001653000.1 CDS APJL_2011 NC_010278.1 2162158 2162481 D pyrophosphatase 2162158..2162481 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850930 YP_001653001.1 CDS APJL_2012 NC_010278.1 2162530 2163210 R complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein complement(2162530..2163210) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851248 YP_001653002.1 CDS APJL_2013 NC_010278.1 2163282 2163500 R hypothetical protein complement(2163282..2163500) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850920 YP_001653003.1 CDS slmA NC_010278.1 2163506 2164114 R FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein complement(2163506..2164114) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850784 YP_001653004.1 CDS dut NC_010278.1 2164220 2164675 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(2164220..2164675) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851012 YP_001653005.1 CDS dfp NC_010278.1 2164684 2165889 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(2164684..2165889) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851066 YP_001653006.1 CDS radC NC_010278.1 2166097 2166759 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 2166097..2166759 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850943 YP_001653007.1 CDS rpmB NC_010278.1 2166928 2167164 D required for 70S ribosome assembly; 50S ribosomal protein L28 2166928..2167164 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851643 YP_001653008.1 CDS rpmG NC_010278.1 2167176 2167346 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2167176..2167346 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850741 YP_001653009.1 CDS APJL_2020 NC_010278.1 2167497 2167682 D hypothetical protein 2167497..2167682 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851435 YP_001653010.1 CDS APJL_2021 NC_010278.1 2167711 2168271 D hypothetical protein 2167711..2168271 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851212 YP_001653011.1 CDS APJL_2022 NC_010278.1 2168283 2168459 R hypothetical protein complement(2168283..2168459) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850716 YP_001653012.1 CDS argD1 NC_010278.1 2168621 2169916 D catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 2168621..2169916 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851209 YP_001653013.1 CDS ddc NC_010278.1 2170045 2171580 D L-2,4-diaminobutyrate decarboxylase 2170045..2171580 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850980 YP_001653014.1 CDS APJL_2025 NC_010278.1 2171639 2171908 R hypothetical protein complement(2171639..2171908) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851068 YP_001653015.1 CDS APJL_2026 NC_010278.1 2171926 2173146 R putative inner membrane protein complement(2171926..2173146) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851633 YP_001653016.1 CDS APJL_2027 NC_010278.1 2173442 2173774 D hypothetical protein 2173442..2173774 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850901 YP_001653017.1 CDS trmA2 NC_010278.1 2173937 2175043 D catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 2173937..2175043 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850814 YP_001653018.1 CDS corA NC_010278.1 2175544 2176497 R responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA complement(2175544..2176497) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851626 YP_001653019.1 CDS ubiE NC_010278.1 2176798 2177574 D ubiquinone/menaquinone biosynthesis methyltransferase 2176798..2177574 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851636 YP_001653020.1 CDS APJL_2031 NC_010278.1 2177610 2178242 D hypothetical protein 2177610..2178242 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851304 YP_001653021.1 CDS ubiB NC_010278.1 2178239 2179873 D ubiquinone biosynthesis protein 2178239..2179873 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850742 YP_001653022.1 CDS tatA NC_010278.1 2179965 2180195 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 2179965..2180195 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851026 YP_001653023.1 CDS tatB NC_010278.1 2180199 2180786 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 2180199..2180786 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851025 YP_001653024.1 CDS tatC NC_010278.1 2180950 2181522 D sec-independent protein secretion pathway component 2180950..2181522 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851069 YP_001653025.1 CDS hemB NC_010278.1 2181582 2182601 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2181582..2182601 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851149 YP_001653026.1 CDS APJL_2037 NC_010278.1 2182688 2183050 D hypothetical protein 2182688..2183050 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851077 YP_001653027.1 CDS mutM NC_010278.1 2183101 2183922 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(2183101..2183922) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850907 YP_001653028.1 CDS brnQ NC_010278.1 2183985 2185277 R branched-chain amino acid permease complement(2183985..2185277) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851877 YP_001653029.1 CDS fabG NC_010278.1 2185403 2186128 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(2185403..2186128) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852018 YP_001653030.1 CDS fabD NC_010278.1 2186246 2187181 R malonyl CoA-acyl carrier protein transacylase complement(2186246..2187181) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852021 YP_001653031.1 CDS APJL_2042 NC_010278.1 2187248 2187994 R hypothetical protein complement(2187248..2187994) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851930 YP_001653032.1 CDS ispB NC_010278.1 2188031 2189026 R octaprenyl-diphosphate synthase complement(2188031..2189026) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851904 YP_001653033.1 CDS APJL_2044 NC_010278.1 2189315 2190133 D hypothetical protein 2189315..2190133 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851770 YP_001653034.1 CDS APJL_2045 NC_010278.1 2190297 2190848 D flavoprotein 2190297..2190848 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851824 YP_001653035.1 CDS APJL_2046 NC_010278.1 2191049 2191462 D hypothetical protein 2191049..2191462 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851817 YP_001653036.1 CDS rplU NC_010278.1 2191791 2192126 D 50S ribosomal protein L21 2191791..2192126 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852026 YP_001653037.1 CDS rpmA NC_010278.1 2192147 2192404 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 2192147..2192404 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851821 YP_001653038.1 CDS APJL_2049 NC_010278.1 2192439 2193428 D putative transport protein 2192439..2193428 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851818 YP_001653039.1 CDS APJL_2050 NC_010278.1 2193425 2193595 D hypothetical protein 2193425..2193595 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852031 YP_001653040.1 CDS APJL_2051 NC_010278.1 2193657 2195126 R hypothetical protein complement(2193657..2195126) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851840 YP_001653041.1 CDS APJL_2052 NC_010278.1 2195242 2196051 R HAD superfamily hydrolase complement(2195242..2196051) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851867 YP_001653042.1 CDS APJL_2053 NC_010278.1 2196026 2196178 D hypothetical protein 2196026..2196178 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852029 YP_001653043.1 CDS comF NC_010278.1 2196171 2196848 D competence protein F 2196171..2196848 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851845 YP_001653044.1 CDS rsmC NC_010278.1 2197283 2198272 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(2197283..2198272) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851672 YP_001653045.1 CDS holD NC_010278.1 2198407 2198799 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 2198407..2198799 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851986 YP_001653046.1 CDS rimI NC_010278.1 2198792 2199229 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 2198792..2199229 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851515 YP_001653047.1 CDS srmB NC_010278.1 2199252 2200601 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2199252..2200601 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851886 YP_001653048.1 CDS pdxH NC_010278.1 2200679 2201308 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2200679..2201308 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851698 YP_001653049.1 CDS hbpA2 NC_010278.1 2201377 2203014 R heme-binding protein A complement(2201377..2203014) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851924 YP_001653050.1 CDS aldA NC_010278.1 2203205 2204686 R putative aldehyde dehydrogenase complement(2203205..2204686) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851711 YP_001653051.1 CDS APJL_2062 NC_010278.1 2204892 2205461 R inner membrane protein complement(2204892..2205461) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852010 YP_001653052.1 CDS fhuC NC_010278.1 2205703 2206467 D ABC-type cobalamin/Fe3+-siderophores transportsystems, ATPase components 2205703..2206467 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852827 YP_001653053.1 CDS fhuD NC_010278.1 2206467 2207423 D ferrichrome-binding periplasmic protein 2206467..2207423 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852011 YP_001653054.1 CDS fhuB NC_010278.1 2207417 2209369 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 2207417..2209369 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852024 YP_001653055.1 CDS fhuA NC_010278.1 2209416 2211503 D outer membrane ferric hydroxamate receptor 2209416..2211503 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851905 YP_001653056.1 CDS APJL_2067 NC_010278.1 2211570 2211887 D hypothetical protein 2211570..2211887 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851190 YP_001653057.1 CDS purC NC_010278.1 2211978 2212835 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2211978..2212835) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852014 YP_001653058.1 CDS hisG NC_010278.1 2213204 2214103 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2213204..2214103 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852071 YP_001653059.1 CDS hisD NC_010278.1 2214219 2215505 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2214219..2215505 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852057 YP_001653060.1 CDS hisC2 NC_010278.1 2215629 2216681 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2215629..2216681 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852080 YP_001653061.1 CDS APJL_2072 NC_010278.1 2216792 2217085 D transposase IS200-like protein 2216792..2217085 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851682 YP_001653062.1 CDS hisB NC_010278.1 2217207 2218292 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2217207..2218292 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852099 YP_001653063.1 CDS APJL_2074 NC_010278.1 2218634 2219587 D hypothetical protein 2218634..2219587 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852084 YP_001653064.1 CDS hisH NC_010278.1 2219604 2220197 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2219604..2220197 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852109 YP_001653065.1 CDS hisA NC_010278.1 2220318 2221070 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2220318..2221070 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852115 YP_001653066.2 CDS hisF NC_010278.1 2221052 2221825 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2221052..2221825 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852117 YP_001653067.1 CDS hisI NC_010278.1 2221954 2222598 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2221954..2222598 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852079 YP_001653068.1 CDS APJL_2079 NC_010278.1 2222719 2223384 D hypothetical protein 2222719..2223384 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852039 YP_001653069.1 CDS map NC_010278.1 2223491 2224297 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 2223491..2224297 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852137 YP_001653070.1 CDS APJL_2081 NC_010278.1 2224531 2225319 D hypothetical protein 2224531..2225319 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852685 YP_001653071.1 CDS APJL_2082 NC_010278.1 2225462 2225956 R thiol-disulfide isomerase and thioredoxins complement(2225462..2225956) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852668 YP_001653072.1 CDS scrR NC_010278.1 2225989 2227008 R sucrose operon repressor complement(2225989..2227008) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852561 YP_001653073.1 CDS scrB NC_010278.1 2227079 2228515 R sucrose-6-phosphate hydrolase complement(2227079..2228515) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852520 YP_001653074.1 CDS rbsK3 NC_010278.1 2228567 2229490 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(2228567..2229490) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852513 YP_001653075.1 CDS sufI2 NC_010278.1 2229634 2230713 D copper-containing nitrite reductase 2229634..2230713 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852504 YP_001653076.1 CDS lolE NC_010278.1 2230781 2232031 R part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE complement(2230781..2232031) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852441 YP_001653077.1 CDS lolD NC_010278.1 2232031 2232744 R lipoprotein releasing system ATP-binding protein complement(2232031..2232744) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852432 YP_001653078.1 CDS lolC NC_010278.1 2232812 2233984 R lipoprotein releasing system transmembrane protein complement(2232812..2233984) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852426 YP_001653079.1 CDS APJL_2090 NC_010278.1 2234109 2235059 R Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase complement(2234109..2235059) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852415 YP_001653080.1 CDS kdsA NC_010278.1 2235116 2235970 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(2235116..2235970) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852371 YP_001653081.1 CDS APJL_2092 NC_010278.1 2236021 2236887 R hypothetical protein complement(2236021..2236887) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852362 YP_001653082.1 CDS hemK NC_010278.1 2236871 2237833 R protein-glutamine N-methyl transferase complement(2236871..2237833) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852191 YP_001653083.1 CDS APJL_2094 NC_010278.1 2237763 2238290 R hypothetical protein complement(2237763..2238290) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852385 YP_001653084.1 CDS prfA NC_010278.1 2238353 2239354 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(2238353..2239354) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852325 YP_001653085.1 CDS sseA NC_010278.1 2239587 2240957 R rhodanese-related sulfur transferase complement(2239587..2240957) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852497 YP_001653086.1 CDS APJL_2097 NC_010278.1 2240966 2241958 R putative inner membrane protein complement(2240966..2241958) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852549 APJL_T002 tRNA APJL_T002 NC_010278.1 69550 69629 D tRNA-Ile 69550..69629 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851671 APJL_T003 tRNA APJL_T003 NC_010278.1 69678 69756 D tRNA-Ala 69678..69756 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851599 APJL_T006 tRNA APJL_T006 NC_010278.1 256948 257040 D tRNA-Ser 256948..257040 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851221 APJL_T008 tRNA APJL_T008 NC_010278.1 283247 283326 D tRNA-Ile 283247..283326 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851046 APJL_T009 tRNA APJL_T009 NC_010278.1 283371 283450 D tRNA-Glu 283371..283450 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850874 APJL_T012 tRNA APJL_T012 NC_010278.1 350988 351066 D tRNA-Asn 350988..351066 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850749 APJL_T013 tRNA APJL_T013 NC_010278.1 495149 495228 D tRNA-Met 495149..495228 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851558 APJL_T014 tRNA APJL_T014 NC_010278.1 681139 681218 D tRNA-Met 681139..681218 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852847 APJL_T015 tRNA APJL_T015 NC_010278.1 813054 813142 R tRNA-Leu complement(813054..813142) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852638 APJL_T016 tRNA APJL_T016 NC_010278.1 835398 835477 D tRNA-Val 835398..835477 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852613 APJL_T017 tRNA APJL_T017 NC_010278.1 847029 847105 R tRNA-Cys complement(847029..847105) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852596 APJL_T018 tRNA APJL_T018 NC_010278.1 847120 847198 R tRNA-Gly complement(847120..847198) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852594 APJL_T019 tRNA APJL_T019 NC_010278.1 905935 906014 D tRNA-Met 905935..906014 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852532 APJL_T020 tRNA APJL_T020 NC_010278.1 907849 907937 D tRNA-Leu 907849..907937 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852528 APJL_T021 tRNA APJL_T021 NC_010278.1 1004722 1004801 R tRNA-Arg complement(1004722..1004801) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852417 APJL_T022 tRNA APJL_T022 NC_010278.1 1004842 1004921 R tRNA-Pro complement(1004842..1004921) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852416 APJL_T023 tRNA APJL_T023 NC_010278.1 1280680 1280757 R tRNA-Gln complement(1280680..1280757) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851853 APJL_T024 tRNA APJL_T024 NC_010278.1 1280803 1280880 R tRNA-Gln complement(1280803..1280880) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851173 APJL_T025 tRNA APJL_T025 NC_010278.1 1280903 1280990 R tRNA-Leu complement(1280903..1280990) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851852 APJL_T026 tRNA APJL_T026 NC_010278.1 1280991 1281070 R tRNA-Met complement(1280991..1281070) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850918 APJL_T027 tRNA APJL_T027 NC_010278.1 1415167 1415245 R tRNA-Val complement(1415167..1415245) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852089 APJL_T028 tRNA APJL_T028 NC_010278.1 1415293 1415371 R tRNA-Val complement(1415293..1415371) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852090 APJL_T029 tRNA APJL_T029 NC_010278.1 1415419 1415497 R tRNA-Val complement(1415419..1415497) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852110 APJL_T030 tRNA APJL_T030 NC_010278.1 1415543 1415621 R tRNA-Val complement(1415543..1415621) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852095 APJL_T031 tRNA APJL_T031 NC_010278.1 1417314 1417392 D tRNA-Ala 1417314..1417392 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852111 APJL_T032 tRNA APJL_T032 NC_010278.1 1421935 1422014 R tRNA-Asp complement(1421935..1422014) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852130 APJL_T033 tRNA APJL_T033 NC_010278.1 1422053 1422132 R tRNA-Asp complement(1422053..1422132) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852128 APJL_T034 tRNA APJL_T034 NC_010278.1 1491639 1491717 R tRNA-Gly complement(1491639..1491717) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852765 APJL_T035 tRNA APJL_T035 NC_010278.1 1491761 1491850 R tRNA-Leu complement(1491761..1491850) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852771 APJL_T036 tRNA APJL_T036 NC_010278.1 1491880 1491969 R tRNA-Leu complement(1491880..1491969) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852483 APJL_T037 tRNA APJL_T037 NC_010278.1 1491989 1492067 R tRNA-Gly complement(1491989..1492067) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852150 APJL_T038 tRNA APJL_T038 NC_010278.1 1492091 1492180 R tRNA-Leu complement(1492091..1492180) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852595 APJL_T039 tRNA APJL_T039 NC_010278.1 1492189 1492267 R tRNA-Gly complement(1492189..1492267) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852530 APJL_T040 tRNA APJL_T040 NC_010278.1 1520868 1520947 R tRNA-Arg complement(1520868..1520947) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5852413 APJL_T041 tRNA APJL_T041 NC_010278.1 1521017 1521096 R tRNA-Arg complement(1521017..1521096) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851782 APJL_T042 tRNA APJL_T042 NC_010278.1 1521107 1521204 R tRNA-Ser complement(1521107..1521204) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851977 APJL_T045 tRNA APJL_T045 NC_010278.1 1530990 1531068 R tRNA-Ala complement(1530990..1531068) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851051 APJL_T046 tRNA APJL_T046 NC_010278.1 1531117 1531196 R tRNA-Ile complement(1531117..1531196) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850765 APJL_T048 tRNA APJL_T048 NC_010278.1 1661939 1662017 D tRNA-Thr 1661939..1662017 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851152 APJL_T049 tRNA APJL_T049 NC_010278.1 1690318 1690396 R tRNA-Thr complement(1690318..1690396) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851214 APJL_T050 tRNA APJL_T050 NC_010278.1 1690397 1690474 R tRNA-Gly complement(1690397..1690474) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850844 APJL_T051 tRNA APJL_T051 NC_010278.1 1690516 1690603 R tRNA-Tyr complement(1690516..1690603) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851108 APJL_T052 tRNA APJL_T052 NC_010278.1 1690637 1690715 R tRNA-Thr complement(1690637..1690715) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851298 APJL_T053 tRNA APJL_T053 NC_010278.1 1718611 1718689 R tRNA-Trp complement(1718611..1718689) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850725 APJL_T054 tRNA APJL_T054 NC_010278.1 1718736 1718815 R tRNA-Asp complement(1718736..1718815) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851260 APJL_T058 tRNA APJL_T058 NC_010278.1 1722344 1722422 R tRNA-Glu complement(1722344..1722422) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851003 APJL_T060 tRNA APJL_T060 NC_010278.1 1724312 1724391 R tRNA-Pro complement(1724312..1724391) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851750 APJL_T061 tRNA APJL_T061 NC_010278.1 1724417 1724495 R tRNA-His complement(1724417..1724495) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851889 APJL_T062 tRNA APJL_T062 NC_010278.1 1724523 1724602 R tRNA-Arg complement(1724523..1724602) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851929 APJL_T063 tRNA APJL_T063 NC_010278.1 1749469 1749562 D tRNA-Sec 1749469..1749562 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851834 APJL_T066 tRNA APJL_T066 NC_010278.1 1834009 1834087 R tRNA-Ala complement(1834009..1834087) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850837 APJL_T067 tRNA APJL_T067 NC_010278.1 1834136 1834215 R tRNA-Ile complement(1834136..1834215) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851344 APJL_T069 tRNA APJL_T069 NC_010278.1 1938673 1938751 D tRNA-Phe 1938673..1938751 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851639 APJL_T070 tRNA APJL_T070 NC_010278.1 1938754 1938832 D tRNA-Asn 1938754..1938832 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851186 APJL_T071 tRNA APJL_T071 NC_010278.1 1938962 1939040 D tRNA-Phe 1938962..1939040 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851035 APJL_T072 tRNA APJL_T072 NC_010278.1 1939043 1939121 D tRNA-Asn 1939043..1939121 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851125 APJL_T073 tRNA APJL_T073 NC_010278.1 2003165 2003243 R tRNA-Lys complement(2003165..2003243) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851325 APJL_T074 tRNA APJL_T074 NC_010278.1 2003275 2003353 R tRNA-Lys complement(2003275..2003353) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851535 APJL_T075 tRNA APJL_T075 NC_010278.1 2003374 2003452 R tRNA-Lys complement(2003374..2003452) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851277 APJL_T077 tRNA APJL_T077 NC_010278.1 2028720 2028799 D tRNA-Ile 2028720..2028799 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851258 APJL_T078 tRNA APJL_T078 NC_010278.1 2028848 2028926 D tRNA-Ala 2028848..2028926 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851660 APJL_T081 tRNA APJL_T081 NC_010278.1 2175149 2175241 D tRNA-Ser 2175149..2175241 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850884 APJL_T082 tRNA APJL_T082 NC_010278.1 2175322 2175414 D tRNA-Ser 2175322..2175414 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850821 APJL_R001 rRNA APJL_R001 NC_010278.1 67935 69465 D 16S ribosomal RNA 67935..69465 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851569 APJL_R004 rRNA APJL_R004 NC_010278.1 70022 72924 D 23S ribosomal RNA 70022..72924 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851502 APJL_R005 rRNA APJL_R005 NC_010278.1 73083 73200 D 5S ribosomal RNA 73083..73200 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851379 APJL_R007 rRNA APJL_R007 NC_010278.1 281630 283162 D 16S ribosomal RNA 281630..283162 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851442 APJL_R010 rRNA APJL_R010 NC_010278.1 283668 286570 D 23S ribosomal RNA 283668..286570 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851637 APJL_R011 rRNA APJL_R011 NC_010278.1 286681 286798 D 5S ribosomal RNA 286681..286798 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851331 APJL_R043 rRNA APJL_R043 NC_010278.1 1527546 1527663 R 5S ribosomal RNA complement(1527546..1527663) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850720 APJL_R044 rRNA APJL_R044 NC_010278.1 1527822 1530724 R 23S ribosomal RNA complement(1527822..1530724) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851265 APJL_R047 rRNA APJL_R047 NC_010278.1 1531281 1532813 R 16S ribosomal RNA complement(1531281..1532813) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850769 APJL_R055 rRNA APJL_R055 NC_010278.1 1718824 1718941 R 5S ribosomal RNA complement(1718824..1718941) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851306 APJL_R056 rRNA APJL_R056 NC_010278.1 1718996 1719113 R 5S ribosomal RNA complement(1718996..1719113) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850956 APJL_R057 rRNA APJL_R057 NC_010278.1 1719224 1722126 R 23S ribosomal RNA complement(1719224..1722126) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850870 APJL_R059 rRNA APJL_R059 NC_010278.1 1722577 1724109 R 16S ribosomal RNA complement(1722577..1724109) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851791 APJL_R064 rRNA APJL_R064 NC_010278.1 1830565 1830682 R 5S ribosomal RNA complement(1830565..1830682) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850826 APJL_R065 rRNA APJL_R065 NC_010278.1 1830841 1833743 R 23S ribosomal RNA complement(1830841..1833743) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850831 APJL_R068 rRNA APJL_R068 NC_010278.1 1834300 1835832 R 16S ribosomal RNA complement(1834300..1835832) Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850856 APJL_R076 rRNA APJL_R076 NC_010278.1 2027103 2028635 D 16S ribosomal RNA 2027103..2028635 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851620 APJL_R079 rRNA APJL_R079 NC_010278.1 2029192 2032094 D 23S ribosomal RNA 2029192..2032094 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5850835 APJL_R080 rRNA APJL_R080 NC_010278.1 2032253 2032370 D 5S ribosomal RNA 2032253..2032370 Actinobacillus pleuropneumoniae serovar 3 str. JL03 5851443