-- dump date 20140618_191813 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_003097821.1 256374161 8331322 98..1831 1 NC_013093.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1831 dnaA 8331322 dnaA Actinosynnema mirum DSM 43827 chromosomal replication initiation protein YP_003097821.1 98 D 446462 CDS YP_003097822.1 256374162 8324144 2628..3764 1 NC_013093.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3764 8324144 Amir_0002 Actinosynnema mirum DSM 43827 DNA polymerase III subunit beta YP_003097822.1 2628 D 446462 CDS YP_003097823.1 256374163 8324145 3806..4720 1 NC_013093.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase-like protein 4720 8324145 Amir_0003 Actinosynnema mirum DSM 43827 6-phosphogluconate dehydrogenase-like protein YP_003097823.1 3806 D 446462 CDS YP_003097824.1 256374164 8324146 4728..5843 1 NC_013093.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5843 recF 8324146 recF Actinosynnema mirum DSM 43827 recombination protein F YP_003097824.1 4728 D 446462 CDS YP_003097825.1 256374165 8324147 6031..6462 1 NC_013093.1 PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721; hypothetical protein 6462 8324147 Amir_0005 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097825.1 6031 D 446462 CDS YP_003097826.1 256374166 8324148 6701..8674 1 NC_013093.1 KEGG: bha:BH0006 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; DNA gyrase subunit B domain protein; TOPRIM domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; DNA gyrase subunit B 8674 8324148 Amir_0006 Actinosynnema mirum DSM 43827 DNA gyrase subunit B YP_003097826.1 6701 D 446462 CDS YP_003097827.1 256374167 8324149 8721..11243 1 NC_013093.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 11243 8324149 Amir_0007 Actinosynnema mirum DSM 43827 DNA gyrase subunit A YP_003097827.1 8721 D 446462 CDS YP_003097828.1 256374168 8324150 11278..12144 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 12144 8324150 Amir_0008 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097828.1 11278 D 446462 CDS YP_003097829.1 256374169 8324152 12309..12428 1 NC_013093.1 hypothetical protein 12428 8324152 Amir_0009 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097829.1 12309 D 446462 CDS YP_003097830.1 256374170 8324154 complement(12873..13304) 1 NC_013093.1 PFAM: DoxX family protein; KEGG: gur:Gura_3338 DoxX family protein; DoxX family protein 13304 8324154 Amir_0010 Actinosynnema mirum DSM 43827 DoxX family protein YP_003097830.1 12873 R 446462 CDS YP_003097831.1 256374171 8324155 13441..13986 1 NC_013093.1 KEGG: similar to Host cell factor C1; hypothetical protein 13986 8324155 Amir_0011 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097831.1 13441 D 446462 CDS YP_003097832.1 256374172 8324156 complement(14069..14509) 1 NC_013093.1 KEGG: rpt:Rpal_3590 histon H1; hypothetical protein 14509 8324156 Amir_0012 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097832.1 14069 R 446462 CDS YP_003097833.1 256374173 8324157 14769..15317 1 NC_013093.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: bba:Bd0177 peptidyl-prolyl cis-trans isomerase; peptidylprolyl isomerase 15317 8324157 Amir_0013 Actinosynnema mirum DSM 43827 peptidylprolyl isomerase YP_003097833.1 14769 D 446462 CDS YP_003097834.1 256374174 8324158 15317..16213 1 NC_013093.1 PFAM: rhomboid family protein; KEGG: bsu:BSU24870 hypothetical protein; rhomboid family protein 16213 8324158 Amir_0014 Actinosynnema mirum DSM 43827 rhomboid family protein YP_003097834.1 15317 D 446462 CDS YP_003097835.1 256374175 8324159 complement(16463..16885) 1 NC_013093.1 hypothetical protein 16885 8324159 Amir_0015 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097835.1 16463 R 446462 CDS YP_003097836.1 256374176 8324160 complement(17118..17384) 1 NC_013093.1 integral membrane protein involved in inhibition of the Z-ring formation; septation inhibitor protein 17384 8324160 Amir_0016 Actinosynnema mirum DSM 43827 septation inhibitor protein YP_003097836.1 17118 R 446462 CDS YP_003097837.1 256374177 8324161 17775..18836 1 NC_013093.1 TIGRFAM: sortase family protein; PFAM: peptidase C60 sortase A and B; KEGG: sus:Acid_5377 sortase family protein; sortase family protein 18836 8324161 Amir_0017 Actinosynnema mirum DSM 43827 sortase family protein YP_003097837.1 17775 D 446462 CDS YP_003097838.1 256374178 8324162 18838..18996 1 NC_013093.1 hypothetical protein 18996 8324162 Amir_0018 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097838.1 18838 D 446462 CDS YP_003097839.1 256374179 8324163 complement(19042..20388) 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ade:Adeh_3296 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Ferredoxin--NADP(+) reductase 20388 8324163 Amir_0019 Actinosynnema mirum DSM 43827 Ferredoxin--NADP(+) reductase YP_003097839.1 19042 R 446462 CDS YP_003097840.1 256374180 8324164 20454..21095 1 NC_013093.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: swi:Swit_3227 anthranilate synthase, component II; glutamine amidotransferase 21095 8324164 Amir_0020 Actinosynnema mirum DSM 43827 glutamine amidotransferase YP_003097840.1 20454 D 446462 CDS YP_003097841.1 256374181 8324165 complement(21196..23241) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: bha:BH2504 serine/threonine protein kinase; serine/threonine protein kinase 23241 8324165 Amir_0021 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003097841.1 21196 R 446462 CDS YP_003097842.1 256374182 8324166 complement(23322..25025) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: ade:Adeh_3649 serine/threonine protein kinase; serine/threonine protein kinase 25025 8324166 Amir_0022 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003097842.1 23322 R 446462 CDS YP_003097843.1 256374183 8324167 complement(25025..26491) 1 NC_013093.1 PFAM: penicillin-binding protein transpeptidase; KEGG: penicillin-binding protein 2; K05515 penicillin binding protein 2; peptidoglycan glycosyltransferase 26491 8324167 Amir_0023 Actinosynnema mirum DSM 43827 peptidoglycan glycosyltransferase YP_003097843.1 25025 R 446462 CDS YP_003097844.1 256374184 8324168 complement(26488..27951) 1 NC_013093.1 PFAM: cell cycle protein; KEGG: bcb:BCB4264_A4012 stage V sporulation protein E; cell cycle protein 27951 8324168 Amir_0024 Actinosynnema mirum DSM 43827 cell cycle protein YP_003097844.1 26488 R 446462 CDS YP_003097845.1 256374185 8324169 complement(27955..29379) 1 NC_013093.1 PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: tgr:Tgr7_0952 protein phosphatase 2C-like protein; protein serine/threonine phosphatase 29379 8324169 Amir_0025 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003097845.1 27955 R 446462 CDS YP_003097846.1 256374186 8324170 complement(29376..29840) 1 NC_013093.1 PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: mxa:MXAN_4649 FHA domain protein; FHA domain containing protein 29840 8324170 Amir_0026 Actinosynnema mirum DSM 43827 FHA domain containing protein YP_003097846.1 29376 R 446462 CDS YP_003097847.1 256374187 8324171 complement(29891..31153) 1 NC_013093.1 PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: eba:ebA2155 hypothetical protein; FHA domain containing protein 31153 8324171 Amir_0027 Actinosynnema mirum DSM 43827 FHA domain containing protein YP_003097847.1 29891 R 446462 CDS YP_003097848.1 256374188 8324173 31797..32417 1 NC_013093.1 hypothetical protein 32417 8324173 Amir_0028 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097848.1 31797 D 446462 CDS YP_003097849.1 256374189 8324174 32468..33103 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: xca:xccb100_0085 hypothetical protein; NAD-dependent epimerase/dehydratase 33103 8324174 Amir_0029 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003097849.1 32468 D 446462 CDS YP_003097850.1 256374190 8324175 complement(33316..34593) 1 NC_013093.1 KEGG: bur:Bcep18194_B3008 FAD-linked oxidoreductase; TIGRFAM: FAD-linked oxidoreductase; PFAM: D-arabinono-14-lactone oxidase; FAD linked oxidase domain protein; FAD-linked oxidoreductase 34593 8324175 Amir_0030 Actinosynnema mirum DSM 43827 FAD-linked oxidoreductase YP_003097850.1 33316 R 446462 CDS YP_003097851.1 256374191 8324176 34677..35864 1 NC_013093.1 PFAM: alanine racemase domain protein; KEGG: bur:Bcep18194_B3007 amino acid aldolase or racemase-like; alanine racemase domain-containing protein 35864 8324176 Amir_0031 Actinosynnema mirum DSM 43827 alanine racemase domain-containing protein YP_003097851.1 34677 D 446462 CDS YP_003097852.1 256374192 8324177 complement(35861..36493) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce5559 HTH-type transcriptional regulator BetI; TetR family transcriptional regulator 36493 8324177 Amir_0032 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003097852.1 35861 R 446462 CDS YP_003097853.1 256374193 8324178 36613..37875 1 NC_013093.1 TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; KEGG: hch:HCH_06907 beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase; beta-galactosidase 37875 8324178 Amir_0033 Actinosynnema mirum DSM 43827 beta-galactosidase YP_003097853.1 36613 D 446462 CDS YP_003097854.1 256374194 8324179 37872..39179 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: ccs:CCNA_02400 transporter, major facilitator superfamily; major facilitator superfamily protein 39179 8324179 Amir_0034 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003097854.1 37872 D 446462 CDS YP_003097855.1 256374195 8324180 39176..39943 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: hypothetical protein; short-chain dehydrogenase/reductase SDR 39943 8324180 Amir_0035 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003097855.1 39176 D 446462 CDS YP_003097856.1 256374196 8324181 complement(40316..40678) 1 NC_013093.1 hypothetical protein 40678 8324181 Amir_0036 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097856.1 40316 R 446462 CDS YP_003097857.1 256374197 8324182 41233..42615 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; hypothetical protein; KEGG: hypothetical protein; XRE family transcriptional regulator 42615 8324182 Amir_0037 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003097857.1 41233 D 446462 CDS YP_003097858.1 256374198 8324183 42689..43585 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: bcz:BCZK4351 homoserine kinase type II (protein kinase fold); aminoglycoside phosphotransferase 43585 8324183 Amir_0038 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003097858.1 42689 D 446462 CDS YP_003097859.1 256374199 8324184 43715..43996 1 NC_013093.1 hypothetical protein 43996 8324184 Amir_0039 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097859.1 43715 D 446462 CDS YP_003097860.1 256374200 8324185 complement(44172..45191) 1 NC_013093.1 PFAM: copper resistance D domain protein; KEGG: bja:bll4878 copper export protein; copper resistance D domain-containing protein 45191 8324185 Amir_0040 Actinosynnema mirum DSM 43827 copper resistance D domain-containing protein YP_003097860.1 44172 R 446462 CDS YP_003097861.1 256374201 8324186 complement(45188..45736) 1 NC_013093.1 PFAM: copper resistance protein CopC; KEGG: bra:BRADO4155 copper resistance protein; copper resistance protein CopC 45736 8324186 Amir_0041 Actinosynnema mirum DSM 43827 copper resistance protein CopC YP_003097861.1 45188 R 446462 CDS YP_003097862.1 256374202 8324187 complement(45733..46482) 1 NC_013093.1 PFAM: nuclear export factor GLE1; KEGG: sme:SMa1200 hypothetical protein; nuclear export factor GLE1 46482 8324187 Amir_0042 Actinosynnema mirum DSM 43827 nuclear export factor GLE1 YP_003097862.1 45733 R 446462 CDS YP_003097863.1 256374203 8324188 complement(46508..47065) 1 NC_013093.1 KEGG: bxe:Bxe_B0776 membrane glycoprotein; hypothetical protein 47065 8324188 Amir_0043 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097863.1 46508 R 446462 CDS YP_003097864.1 256374204 8324189 47159..48991 1 NC_013093.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: ppw:PputW619_2676 choline/carnitine/betaine transporter; choline/carnitine/betaine transporter 48991 8324189 Amir_0044 Actinosynnema mirum DSM 43827 choline/carnitine/betaine transporter YP_003097864.1 47159 D 446462 CDS YP_003097865.1 256374205 8324190 complement(49044..49484) 1 NC_013093.1 hypothetical protein 49484 8324190 Amir_0045 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097865.1 49044 R 446462 CDS YP_003097866.1 256374206 8324191 49586..51220 1 NC_013093.1 nuclease (RecB family)-like protein 51220 8324191 Amir_0046 Actinosynnema mirum DSM 43827 nuclease (RecB family)-like protein YP_003097866.1 49586 D 446462 CDS YP_003097867.1 256374207 8324192 complement(51262..52014) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bac:BamMC406_2467 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 52014 8324192 Amir_0047 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003097867.1 51262 R 446462 CDS YP_003097868.1 256374208 8324193 complement(52050..52175) 1 NC_013093.1 hypothetical protein 52175 8324193 Amir_0048 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097868.1 52050 R 446462 CDS YP_003097869.1 256374209 8324194 52353..54134 1 NC_013093.1 PFAM: gamma-glutamyltranspeptidase; KEGG: bbt:BBta_2852 gamma- glutamyltranspeptidase; gamma-glutamyltransferase 54134 8324194 Amir_0049 Actinosynnema mirum DSM 43827 gamma-glutamyltransferase YP_003097869.1 52353 D 446462 CDS YP_003097870.1 256374210 8324195 complement(54212..54541) 1 NC_013093.1 hypothetical protein 54541 8324195 Amir_0050 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097870.1 54212 R 446462 CDS YP_003097871.1 256374211 8324196 complement(55503..55877) 1 NC_013093.1 hypothetical protein 55877 8324196 Amir_0051 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097871.1 55503 R 446462 CDS YP_003097872.1 256374212 8324197 56251..57537 1 NC_013093.1 KEGG: azc:AZC_0951 hypothetical protein; hypothetical protein 57537 8324197 Amir_0052 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097872.1 56251 D 446462 CDS YP_003097873.1 256374213 8324198 57672..59063 1 NC_013093.1 KEGG: FAP262; flagellar associated protein; hypothetical protein 59063 8324198 Amir_0053 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097873.1 57672 D 446462 CDS YP_003097874.1 256374214 8324199 59060..60733 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: rce:RC1_0824 glycosyl transferase family protein; family 2 glycosyl transferase 60733 8324199 Amir_0054 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003097874.1 59060 D 446462 CDS YP_003097875.1 256374215 8324200 complement(60861..64376) 1 NC_013093.1 PFAM: glycosyl transferase family 2; methyltransferase type 12; methyltransferase type 11; KEGG: ppf:Pput_3926 glycosyl transferase family protein; family 2 glycosyl transferase 64376 8324200 Amir_0055 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003097875.1 60861 R 446462 CDS YP_003097876.1 256374216 8324201 complement(64376..65581) 1 NC_013093.1 KEGG: sus:Acid_4178 ribonuclease; hypothetical protein 65581 8324201 Amir_0056 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097876.1 64376 R 446462 CDS YP_003097877.1 256374217 8324202 complement(65703..68078) 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: xcb:XC_3634 glycosyltransferase; group 1 glycosyl transferase 68078 8324202 Amir_0057 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003097877.1 65703 R 446462 CDS YP_003097878.1 256374218 8324203 complement(68337..69401) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: swi:Swit_4011 methyltransferase type 12; type 11 methyltransferase 69401 8324203 Amir_0058 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003097878.1 68337 R 446462 CDS YP_003097879.1 256374219 8324204 complement(69961..70266) 1 NC_013093.1 hypothetical protein 70266 8324204 Amir_0059 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097879.1 69961 R 446462 CDS YP_003097880.1 256374220 8324205 complement(70271..70696) 1 NC_013093.1 PFAM: OsmC family protein; KEGG: mlo:mlr4254 osmotically inducible protein C, ATP/GTP binding protein; OsmC family protein 70696 8324205 Amir_0060 Actinosynnema mirum DSM 43827 OsmC family protein YP_003097880.1 70271 R 446462 CDS YP_003097881.1 256374221 8324207 complement(70942..71337) 1 NC_013093.1 hypothetical protein 71337 8324207 Amir_0061 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097881.1 70942 R 446462 CDS YP_003097882.1 256374222 8324208 71534..73003 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: afw:Anae109_0839 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 73003 8324208 Amir_0062 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003097882.1 71534 D 446462 CDS YP_003097883.1 256374223 8324209 73127..73564 1 NC_013093.1 hypothetical protein 73564 8324209 Amir_0063 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097883.1 73127 D 446462 CDS YP_003097884.1 256374224 8324210 73786..75072 1 NC_013093.1 PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: signal transduction histidine kinase, LytS; K07704 two-component system, LytT family, sensor histidine kinase LytS; signal transduction histidine kinase LytS 75072 8324210 Amir_0064 Actinosynnema mirum DSM 43827 signal transduction histidine kinase LytS YP_003097884.1 73786 D 446462 CDS YP_003097885.1 256374225 8324211 complement(75077..75244) 1 NC_013093.1 hypothetical protein 75244 8324211 Amir_0065 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097885.1 75077 R 446462 CDS YP_003097886.1 256374226 8324212 75285..76157 1 NC_013093.1 PFAM: peptidase S49; KEGG: rce:RC1_1672 proteinase SohB; peptidase S49 76157 8324212 Amir_0066 Actinosynnema mirum DSM 43827 peptidase S49 YP_003097886.1 75285 D 446462 CDS YP_003097887.1 256374227 8324213 76254..77081 1 NC_013093.1 PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; KEGG: gur:Gura_2791 LytTR family two component transcriptional regulator; LytTR family two component transcriptional regulator 77081 8324213 Amir_0067 Actinosynnema mirum DSM 43827 LytTR family two component transcriptional regulator YP_003097887.1 76254 D 446462 CDS YP_003097888.1 256374228 8324214 77078..77500 1 NC_013093.1 hypothetical protein 77500 8324214 Amir_0068 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097888.1 77078 D 446462 CDS YP_003097889.1 256374229 8324215 77504..79315 1 NC_013093.1 PFAM: Na+/solute symporter; KEGG: dac:Daci_5957 SSS family solute/sodium (Na+) symporter; Na+/solute symporter 79315 8324215 Amir_0069 Actinosynnema mirum DSM 43827 Na+/solute symporter YP_003097889.1 77504 D 446462 CDS YP_003097890.1 256374230 8324216 79609..79965 1 NC_013093.1 PFAM: protein of unknown function DUF485; KEGG: gme:Gmet_3287 hypothetical protein; hypothetical protein 79965 8324216 Amir_0070 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097890.1 79609 D 446462 CDS YP_003097891.1 256374231 8324217 79962..81548 1 NC_013093.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: bca:BCE_1726 sodium/solute symporter family protein; SSS sodium solute transporter superfamily protein 81548 8324217 Amir_0071 Actinosynnema mirum DSM 43827 SSS sodium solute transporter superfamily protein YP_003097891.1 79962 D 446462 CDS YP_003097892.1 256374232 8324218 81691..82116 1 NC_013093.1 TIGRFAM: DNA binding domain protein, excisionase family; KEGG: maq:Maqu_3385 DNA binding domain-containing protein; excisionase family DNA binding domain-containing protein 82116 8324218 Amir_0072 Actinosynnema mirum DSM 43827 excisionase family DNA binding domain-containing protein YP_003097892.1 81691 D 446462 CDS YP_003097893.1 256374233 8324219 82184..82774 1 NC_013093.1 KEGG: lpc:LPC_2191 hypothetical protein; hypothetical protein 82774 8324219 Amir_0073 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097893.1 82184 D 446462 CDS YP_003097894.1 256374234 8324220 82815..83162 1 NC_013093.1 PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: rfr:Rfer_3913 rhodanese-like protein; rhodanese domain-containing protein 83162 8324220 Amir_0074 Actinosynnema mirum DSM 43827 rhodanese domain-containing protein YP_003097894.1 82815 D 446462 CDS YP_003097895.1 256374235 8324221 83164..84072 1 NC_013093.1 KEGG: sfu:Sfum_2194 hypothetical protein; hypothetical protein 84072 8324221 Amir_0075 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097895.1 83164 D 446462 CDS YP_003097896.1 256374236 8324222 84163..85212 1 NC_013093.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: hypothetical protein; glycerophosphoryl diester phosphodiesterase 85212 8324222 Amir_0076 Actinosynnema mirum DSM 43827 glycerophosphoryl diester phosphodiesterase YP_003097896.1 84163 D 446462 CDS YP_003097897.1 256374237 8324223 complement(85244..86476) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: jan:Jann_1726 cytochrome P450; cytochrome P450 86476 8324223 Amir_0077 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003097897.1 85244 R 446462 CDS YP_003097898.1 256374238 8324224 86596..87294 1 NC_013093.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: gbm:Gbem_3150 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 87294 8324224 Amir_0078 Actinosynnema mirum DSM 43827 glycerophosphoryl diester phosphodiesterase YP_003097898.1 86596 D 446462 CDS YP_003097899.1 256374239 8324225 87313..88257 1 NC_013093.1 PFAM: SEC-C motif domain protein; SEC-C motif domain-containing protein 88257 8324225 Amir_0079 Actinosynnema mirum DSM 43827 SEC-C motif domain-containing protein YP_003097899.1 87313 D 446462 CDS YP_003097900.1 256374240 8324226 88330..88656 1 NC_013093.1 PFAM: protein of unknown function DUF952; KEGG: rru:Rru_A0513 hypothetical protein; hypothetical protein 88656 8324226 Amir_0080 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097900.1 88330 D 446462 CDS YP_003097901.1 256374241 8324227 88777..89808 1 NC_013093.1 KEGG: xau:Xaut_1560 phenylacetaldoxime dehydratase; phenylacetaldoxime dehydratase 89808 8324227 Amir_0081 Actinosynnema mirum DSM 43827 phenylacetaldoxime dehydratase YP_003097901.1 88777 D 446462 CDS YP_003097902.1 256374242 8324228 complement(89920..90483) 1 NC_013093.1 PFAM: Ferritin Dps family protein; KEGG: hypothetical protein; Ferritin Dps family protein 90483 8324228 Amir_0082 Actinosynnema mirum DSM 43827 Ferritin Dps family protein YP_003097902.1 89920 R 446462 CDS YP_003097903.1 256374243 8324229 complement(90632..91879) 1 NC_013093.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 91879 8324229 Amir_0083 Actinosynnema mirum DSM 43827 arginine deiminase YP_003097903.1 90632 R 446462 CDS YP_003097904.1 256374244 8324230 complement(92019..92672) 1 NC_013093.1 KEGG: bha:BH0832 hypothetical protein; hypothetical protein 92672 8324230 Amir_0084 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097904.1 92019 R 446462 CDS YP_003097905.1 256374245 8324231 complement(92746..93540) 1 NC_013093.1 PFAM: abortive infection protein; KEGG: dal:Dalk_0566 abortive infection protein; abortive infection protein 93540 8324231 Amir_0085 Actinosynnema mirum DSM 43827 abortive infection protein YP_003097905.1 92746 R 446462 CDS YP_003097906.1 256374246 8324232 complement(93550..94308) 1 NC_013093.1 KEGG: scl:sce4194 hypothetical protein; hypothetical protein 94308 8324232 Amir_0086 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097906.1 93550 R 446462 CDS YP_003097907.1 256374247 8324233 94407..95036 1 NC_013093.1 hypothetical protein 95036 8324233 Amir_0087 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097907.1 94407 D 446462 CDS YP_003097908.1 256374248 8324234 complement(95197..96399) 1 NC_013093.1 PFAM: homogentisate 12-dioxygenase; KEGG: bcz:BCZK0217 homogentisate 1,2-dioxygenase; homogentisate 12-dioxygenase 96399 8324234 Amir_0088 Actinosynnema mirum DSM 43827 homogentisate 12-dioxygenase YP_003097908.1 95197 R 446462 CDS YP_003097909.1 256374249 8324235 96535..97335 1 NC_013093.1 KEGG: sus:Acid_6517 hypothetical protein; hypothetical protein 97335 8324235 Amir_0089 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097909.1 96535 D 446462 CDS YP_003097910.1 256374250 8324236 97332..98516 1 NC_013093.1 PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969; KEGG: jan:Jann_1436 fumarylacetoacetate hydrolase; fumarylacetoacetase 98516 8324236 Amir_0090 Actinosynnema mirum DSM 43827 fumarylacetoacetase YP_003097910.1 97332 D 446462 CDS YP_003097911.1 256374251 8324237 98519..99178 1 NC_013093.1 PFAM: regulatory protein IclR; SMART: regulatory protein IclR; KEGG: dac:Daci_0951 IclR family transcriptional regulator; IclR family transcriptional regulator 99178 8324237 Amir_0091 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003097911.1 98519 D 446462 CDS YP_003097912.1 256374252 8324238 99260..100771 1 NC_013093.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: bsu:BSU38760 cytochrome bd ubiquinol oxidase (subunit I); cytochrome bd ubiquinol oxidase subunit I 100771 8324238 Amir_0092 Actinosynnema mirum DSM 43827 cytochrome bd ubiquinol oxidase subunit I YP_003097912.1 99260 D 446462 CDS YP_003097913.1 256374253 8324239 100786..101790 1 NC_013093.1 KEGG: glo:Glov_1209 cytochrome D ubiquinol oxidase, subunit II; TIGRFAM: cytochrome D ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; cytochrome D ubiquinol oxidase, subunit II 101790 8324239 Amir_0093 Actinosynnema mirum DSM 43827 cytochrome D ubiquinol oxidase, subunit II YP_003097913.1 100786 D 446462 CDS YP_003097914.1 256374254 8324240 complement(102023..103051) 1 NC_013093.1 SMART: TIR protein; KEGG: vvy:VV1926 hypothetical protein; TIR protein 103051 8324240 Amir_0094 Actinosynnema mirum DSM 43827 TIR protein YP_003097914.1 102023 R 446462 CDS YP_003097915.1 256374255 8324241 103158..106223 1 NC_013093.1 KEGG: bpt:Bpet3362 HlyB/MsbA family ABC transporter; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; cysteine ABC transporter permease/ATP-binding protein 106223 8324241 Amir_0095 Actinosynnema mirum DSM 43827 cysteine ABC transporter permease/ATP-binding protein YP_003097915.1 103158 D 446462 CDS YP_003097916.1 256374256 8324242 106220..107338 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; GAF domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: pna:Pnap_3765 multi-sensor signal transduction histidine kinase; GAF sensor signal transduction histidine kinase 107338 8324242 Amir_0096 Actinosynnema mirum DSM 43827 GAF sensor signal transduction histidine kinase YP_003097916.1 106220 D 446462 CDS YP_003097917.1 256374257 8324243 complement(107555..108184) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: xca:xccb100_3213 two-component system regulatory protein; LuxR family transcriptional regulator 108184 8324243 Amir_0097 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003097917.1 107555 R 446462 CDS YP_003097918.1 256374258 8324244 108245..108727 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bca:BCE_4174 acetyltransferase; GCN5-like N-acetyltransferase 108727 8324244 Amir_0098 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003097918.1 108245 D 446462 CDS YP_003097919.1 256374259 8324245 complement(108789..109388) 1 NC_013093.1 PFAM: Appr-1-p processing domain protein; KEGG: dal:Dalk_0690 Appr-1-p processing domain protein; Appr-1-p processing domain-containing protein 109388 8324245 Amir_0099 Actinosynnema mirum DSM 43827 Appr-1-p processing domain-containing protein YP_003097919.1 108789 R 446462 CDS YP_003097920.1 256374260 8324246 109492..110394 1 NC_013093.1 PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ank:AnaeK_2061 prephenate dehydratase; Prephenate dehydratase 110394 8324246 Amir_0100 Actinosynnema mirum DSM 43827 Prephenate dehydratase YP_003097920.1 109492 D 446462 CDS YP_003097921.1 256374261 8324247 110391..111002 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: lch:Lcho_3955 phosphoglycerate mutase; phosphoglycerate mutase 111002 8324247 Amir_0101 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003097921.1 110391 D 446462 CDS YP_003097922.1 256374262 8324250 complement(111845..112261) 1 NC_013093.1 hypothetical protein 112261 8324250 Amir_0104 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097922.1 111845 R 446462 CDS YP_003097923.1 256374263 8324251 complement(112255..112677) 1 NC_013093.1 hypothetical protein 112677 8324251 Amir_0105 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097923.1 112255 R 446462 CDS YP_003097924.1 256374264 8324252 complement(112751..112936) 1 NC_013093.1 hypothetical protein 112936 8324252 Amir_0106 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097924.1 112751 R 446462 CDS YP_003097925.1 256374265 8324253 113121..114014 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 114014 8324253 Amir_0107 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003097925.1 113121 D 446462 CDS YP_003097926.1 256374266 8324254 114011..114196 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 114196 8324254 Amir_0108 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097926.1 114011 D 446462 CDS YP_003097927.1 256374267 8324255 complement(114247..114795) 1 NC_013093.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ade:Adeh_1652 peptidylprolyl isomerase; peptidylprolyl isomerase 114795 8324255 Amir_0109 Actinosynnema mirum DSM 43827 peptidylprolyl isomerase YP_003097927.1 114247 R 446462 CDS YP_003097928.1 256374268 8324256 115026..118412 1 NC_013093.1 PFAM: glycoside hydrolase family 31; carbohydrate binding family 6; Ricin B lectin; SMART: cellulose binding type IV; Ricin B lectin; KEGG: aba:Acid345_1956 glycoside hydrolase, family 31; glycoside hydrolase family protein 118412 8324256 Amir_0110 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003097928.1 115026 D 446462 CDS YP_003097929.1 256374269 8324258 complement(120442..120792) 1 NC_013093.1 PFAM: protein of unknown function DUF1025; KEGG: eli:ELI_09390 hypothetical protein; hypothetical protein 120792 8324258 Amir_0112 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097929.1 120442 R 446462 CDS YP_003097930.1 256374270 8324259 complement(120797..121825) 1 NC_013093.1 KEGG: YALI0F05786p; hypothetical protein 121825 8324259 Amir_0113 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097930.1 120797 R 446462 CDS YP_003097931.1 256374271 8324260 121985..122737 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 122737 8324260 Amir_0114 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097931.1 121985 D 446462 CDS YP_003097932.1 256374272 8324261 122738..123901 1 NC_013093.1 PFAM: glutathionylspermidine synthase; KEGG: sus:Acid_7141 glutathionylspermidine synthase; glutathionylspermidine synthase 123901 8324261 Amir_0115 Actinosynnema mirum DSM 43827 glutathionylspermidine synthase YP_003097932.1 122738 D 446462 CDS YP_003097933.1 256374273 8324262 123918..124370 1 NC_013093.1 PFAM: protein of unknown function DUF350; KEGG: met:M446_5403 hypothetical protein; hypothetical protein 124370 8324262 Amir_0116 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097933.1 123918 D 446462 CDS YP_003097934.1 256374274 8324263 complement(124531..125205) 1 NC_013093.1 hypothetical protein 125205 8324263 Amir_0117 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097934.1 124531 R 446462 CDS YP_003097935.1 256374275 8324264 125363..126613 1 NC_013093.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 126613 8324264 Amir_0118 Actinosynnema mirum DSM 43827 seryl-tRNA synthetase YP_003097935.1 125363 D 446462 CDS YP_003097936.1 256374276 8324265 complement(127550..128737) 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; HI0933 family protein; KEGG: sus:Acid_5855 FAD dependent oxidoreductase; FAD dependent oxidoreductase 128737 8324265 Amir_0119 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003097936.1 127550 R 446462 CDS YP_003097937.1 256374277 8324266 complement(128739..129671) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4411 luciferase-like; luciferase-like monooxygenase 129671 8324266 Amir_0120 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003097937.1 128739 R 446462 CDS YP_003097938.1 256374278 8324267 129678..130499 1 NC_013093.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: mno:Mnod_7133 Cof-like hydrolase; Cof-like hydrolase 130499 8324267 Amir_0121 Actinosynnema mirum DSM 43827 Cof-like hydrolase YP_003097938.1 129678 D 446462 CDS YP_003097939.1 256374279 8324268 130616..132532 1 NC_013093.1 KEGG: sml:Smlt0624 transmembrane protein; hypothetical protein 132532 8324268 Amir_0122 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097939.1 130616 D 446462 CDS YP_003097940.1 256374280 8324269 132542..133594 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: rme:Rmet_6128 glycosyl transferase, family 2; ribonuclease III 133594 8324269 Amir_0123 Actinosynnema mirum DSM 43827 ribonuclease III YP_003097940.1 132542 D 446462 CDS YP_003097941.1 256374281 8324270 133597..134106 1 NC_013093.1 PFAM: GtrA family protein; KEGG: GtrA family protein; GtrA family protein 134106 8324270 Amir_0124 Actinosynnema mirum DSM 43827 GtrA family protein YP_003097941.1 133597 D 446462 CDS YP_003097942.1 256374282 8324271 134133..135434 1 NC_013093.1 PFAM: acyltransferase 3; KEGG: acr:Acry_1134 acyltransferase 3; acyltransferase 3 135434 8324271 Amir_0125 Actinosynnema mirum DSM 43827 acyltransferase 3 YP_003097942.1 134133 D 446462 CDS YP_003097943.1 256374283 8324272 135536..137167 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: pae:PA1391 glycosyl transferase; group 1 glycosyl transferase 137167 8324272 Amir_0126 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003097943.1 135536 D 446462 CDS YP_003097944.1 256374284 8324273 137164..138063 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: bcj:BCAL3234 glycosyltransferase; family 2 glycosyl transferase 138063 8324273 Amir_0127 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003097944.1 137164 D 446462 CDS YP_003097945.1 256374285 8324274 138200..139384 1 NC_013093.1 KEGG: gox:GOX1488 UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase-like; UDP-galactopyranose mutase 139384 8324274 Amir_0128 Actinosynnema mirum DSM 43827 UDP-galactopyranose mutase YP_003097945.1 138200 D 446462 CDS YP_003097946.1 256374286 8324275 complement(139453..140256) 1 NC_013093.1 KEGG: pna:Pnap_3593 hypothetical protein; hypothetical protein 140256 8324275 Amir_0129 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097946.1 139453 R 446462 CDS YP_003097947.1 256374287 8324276 complement(140289..141086) 1 NC_013093.1 KEGG: dac:Daci_5514 hypothetical protein; hypothetical protein 141086 8324276 Amir_0130 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097947.1 140289 R 446462 CDS YP_003097948.1 256374288 8324277 complement(141148..141948) 1 NC_013093.1 KEGG: jan:Jann_1080 metallophosphoesterase; hypothetical protein 141948 8324277 Amir_0131 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097948.1 141148 R 446462 CDS YP_003097949.1 256374289 8324278 complement(142456..143352) 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: apl:APL_1469 glycosyl transferase family protein; family 2 glycosyl transferase 143352 8324278 Amir_0132 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003097949.1 142456 R 446462 CDS YP_003097950.1 256374290 8324279 complement(143356..144171) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cbc:CbuK_1550 polysaccharide export ATP- binding protein; ABC transporter 144171 8324279 Amir_0133 Actinosynnema mirum DSM 43827 ABC transporter YP_003097950.1 143356 R 446462 CDS YP_003097951.1 256374291 8324280 complement(144188..145099) 1 NC_013093.1 PFAM: ABC transporter; KEGG: tbd:Tbd_1878 ABC transporter permease protein; ABC transporter 145099 8324280 Amir_0134 Actinosynnema mirum DSM 43827 ABC transporter YP_003097951.1 144188 R 446462 CDS YP_003097952.1 256374292 8324281 complement(145369..145917) 1 NC_013093.1 hypothetical protein 145917 8324281 Amir_0135 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097952.1 145369 R 446462 CDS YP_003097953.1 256374293 8324282 146032..147231 1 NC_013093.1 TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V; KEGG: mlo:mlr0102 aminotransferase; cysteine desulfurase family protein 147231 8324282 Amir_0136 Actinosynnema mirum DSM 43827 cysteine desulfurase family protein YP_003097953.1 146032 D 446462 CDS YP_003097954.1 256374294 8324283 147357..148010 1 NC_013093.1 KEGG: mes:Meso_0486 hypothetical protein; hypothetical protein 148010 8324283 Amir_0137 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097954.1 147357 D 446462 CDS YP_003097955.1 256374295 8324284 complement(148245..149723) 1 NC_013093.1 KEGG: scl:sce7164 hypothetical protein; hypothetical protein 149723 8324284 Amir_0138 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097955.1 148245 R 446462 CDS YP_003097956.1 256374296 8324285 complement(149847..150821) 1 NC_013093.1 TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: hypothetical protein; NAD(P)H quinone oxidoreductase 150821 8324285 Amir_0139 Actinosynnema mirum DSM 43827 NAD(P)H quinone oxidoreductase YP_003097956.1 149847 R 446462 CDS YP_003097957.1 256374297 8324286 150866..151498 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_C_5049 hypothetical protein; GCN5-like N-acetyltransferase 151498 8324286 Amir_0140 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003097957.1 150866 D 446462 CDS YP_003097958.1 256374298 8324287 151575..153095 1 NC_013093.1 PFAM: peptidase M28; protease-associated PA domain protein; KEGG: pag:PLES_21241 aminopeptidase; Aminopeptidase Y 153095 8324287 Amir_0141 Actinosynnema mirum DSM 43827 Aminopeptidase Y YP_003097958.1 151575 D 446462 CDS YP_003097959.1 256374299 8324288 complement(153173..154078) 1 NC_013093.1 PFAM: protein of unknown function zinc metallopeptidase KEGG: rfr:Rfer_2725 protein of unknown function, zinc metallopeptidase; hypothetical protein 154078 8324288 Amir_0142 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097959.1 153173 R 446462 CDS YP_003097960.1 256374300 8324289 complement(154537..156264) 1 NC_013093.1 PFAM: 5'-nucleotidase; metallophosphoesterase; KEGG: scl:sce7039 5'-nucleotidase family protein; 5'-nucleotidase 156264 8324289 Amir_0143 Actinosynnema mirum DSM 43827 5'-nucleotidase YP_003097960.1 154537 R 446462 CDS YP_003097961.1 256374301 8324290 156424..156891 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: acp:A2cp1_4259 transcriptional regulator, MarR family; MarR family transcriptional regulator 156891 8324290 Amir_0144 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003097961.1 156424 D 446462 CDS YP_003097962.1 256374302 8324292 157221..157970 1 NC_013093.1 PFAM: protein of unknown function DUF81; KEGG: sfu:Sfum_1521 protein of unknown function DUF81; hypothetical protein 157970 8324292 Amir_0145 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097962.1 157221 D 446462 CDS YP_003097963.1 256374303 8324293 complement(158047..159114) 1 NC_013093.1 TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: scl:sce8915 histidinol-phosphate transaminase; histidinol-phosphate aminotransferase 159114 8324293 Amir_0146 Actinosynnema mirum DSM 43827 histidinol-phosphate aminotransferase YP_003097963.1 158047 R 446462 CDS YP_003097964.1 256374304 8324294 159236..159919 1 NC_013093.1 PFAM: dienelactone hydrolase; KEGG: cvi:CV_3204 carboxymethylenebutenolidase; dienelactone hydrolase 159919 8324294 Amir_0147 Actinosynnema mirum DSM 43827 dienelactone hydrolase YP_003097964.1 159236 D 446462 CDS YP_003097965.1 256374305 8324295 complement(159963..160340) 1 NC_013093.1 KEGG: GK21229 gene product from transcript GK21229- RA; hypothetical protein 160340 8324295 Amir_0148 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097965.1 159963 R 446462 CDS YP_003097966.1 256374306 8324296 160367..161743 1 NC_013093.1 KEGG: GH10507 gene product from transcript GH10507- RA; hypothetical protein 161743 8324296 Amir_0149 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097966.1 160367 D 446462 CDS YP_003097967.1 256374307 8324297 161743..163089 1 NC_013093.1 KEGG: reu:Reut_B5390 glycin-rich signal peptide protein; hypothetical protein 163089 8324297 Amir_0150 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097967.1 161743 D 446462 CDS YP_003097968.1 256374308 8324298 163086..163844 1 NC_013093.1 hypothetical protein 163844 8324298 Amir_0151 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097968.1 163086 D 446462 CDS YP_003097969.1 256374309 8324299 163955..165910 1 NC_013093.1 TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: sil:SPO1959 acetoacetyl-CoA synthetase; acetoacetyl-CoA synthase 165910 8324299 Amir_0152 Actinosynnema mirum DSM 43827 acetoacetyl-CoA synthase YP_003097969.1 163955 D 446462 CDS YP_003097970.1 256374310 8324302 complement(166576..168750) 1 NC_013093.1 KEGG: SAMD1; sterile alpha motif domain containing 1; hypothetical protein 168750 8324302 Amir_0153 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097970.1 166576 R 446462 CDS YP_003097971.1 256374311 8324303 complement(168872..169687) 1 NC_013093.1 PFAM: beta-lactamase; KEGG: sml:Smlt3132 beta-lactamase; beta-lactamase 169687 8324303 Amir_0154 Actinosynnema mirum DSM 43827 beta-lactamase YP_003097971.1 168872 R 446462 CDS YP_003097972.1 256374312 8324304 169787..171295 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: bur:Bcep18194_A5663 DNA translocase FtsK; LPXTG-motif cell wall anchor domain-containing protein 171295 8324304 Amir_0155 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003097972.1 169787 D 446462 CDS YP_003097973.1 256374313 8324305 complement(171267..172106) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: hha:Hhal_0769 UDP-glucose 4-epimerase; NAD-dependent epimerase/dehydratase 172106 8324305 Amir_0156 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003097973.1 171267 R 446462 CDS YP_003097974.1 256374314 8324306 172215..172442 1 NC_013093.1 hypothetical protein 172442 8324306 Amir_0157 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097974.1 172215 D 446462 CDS YP_003097975.1 256374315 8324307 172593..174020 1 NC_013093.1 hypothetical protein 174020 8324307 Amir_0158 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097975.1 172593 D 446462 CDS YP_003097976.1 256374316 8324308 complement(174010..174810) 1 NC_013093.1 KEGG: scl:sce4085 hypothetical protein; hypothetical protein 174810 8324308 Amir_0159 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097976.1 174010 R 446462 CDS YP_003097977.1 256374317 8324309 174893..176107 1 NC_013093.1 PFAM: C-5 cytosine-specific DNA methylase; KEGG: nmc:NMC1992 modification methylase (cytosine- specific DNA methylase); DNA (cytosine-5-)-methyltransferase 176107 8324309 Amir_0160 Actinosynnema mirum DSM 43827 DNA (cytosine-5-)-methyltransferase YP_003097977.1 174893 D 446462 CDS YP_003097978.1 256374318 8324310 176495..177745 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: ADR019Cp; K01066 esterase / lipase; LPXTG-motif cell wall anchor domain-containing protein 177745 8324310 Amir_0161 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003097978.1 176495 D 446462 CDS YP_003097979.1 256374319 8324311 177884..178057 1 NC_013093.1 hypothetical protein 178057 8324311 Amir_0162 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097979.1 177884 D 446462 CDS YP_003097980.1 256374320 8324312 178054..178677 1 NC_013093.1 PFAM: protein of unknown function DUF1089; KEGG: sme:SMc03980 hypothetical protein; hypothetical protein 178677 8324312 Amir_0163 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097980.1 178054 D 446462 CDS YP_003097981.1 256374321 8324313 complement(178764..179948) 1 NC_013093.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: gbm:Gbem_1434 acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase 179948 8324313 Amir_0164 Actinosynnema mirum DSM 43827 acetyl-CoA acetyltransferase YP_003097981.1 178764 R 446462 CDS YP_003097982.1 256374322 8324314 complement(179961..181772) 1 NC_013093.1 KEGG: CG32656; hypothetical protein 181772 8324314 Amir_0165 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097982.1 179961 R 446462 CDS YP_003097983.1 256374323 8324315 complement(181830..182186) 1 NC_013093.1 hypothetical protein 182186 8324315 Amir_0166 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097983.1 181830 R 446462 CDS YP_003097984.1 256374324 8324316 complement(182183..183073) 1 NC_013093.1 KEGG: ade:Adeh_1681 PE-PGRS family protein; PE-PGRS family protein 183073 8324316 Amir_0167 Actinosynnema mirum DSM 43827 PE-PGRS family protein YP_003097984.1 182183 R 446462 CDS YP_003097985.1 256374325 8324317 complement(183317..184273) 1 NC_013093.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 184273 8324317 Amir_0168 Actinosynnema mirum DSM 43827 prephenate dehydrogenase YP_003097985.1 183317 R 446462 CDS YP_003097986.1 256374326 8324318 complement(184371..185606) 1 NC_013093.1 KEGG: sal:Sala_2314 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein; amidohydrolase 185606 8324318 Amir_0169 Actinosynnema mirum DSM 43827 amidohydrolase YP_003097986.1 184371 R 446462 CDS YP_003097987.1 256374327 8324319 185647..186177 1 NC_013093.1 hypothetical protein 186177 8324319 Amir_0170 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097987.1 185647 D 446462 CDS YP_003097988.1 256374328 8324320 186174..186656 1 NC_013093.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: gur:Gura_0055 CMP/dCMP deaminase, zinc- binding; zinc-binding CMP/dCMP deaminase 186656 8324320 Amir_0171 Actinosynnema mirum DSM 43827 zinc-binding CMP/dCMP deaminase YP_003097988.1 186174 D 446462 CDS YP_003097989.1 256374329 8324322 complement(186876..188189) 1 NC_013093.1 PFAM: integrase family protein; KEGG: sus:Acid_5994 phage integrase family protein; integrase family protein 188189 8324322 Amir_0172 Actinosynnema mirum DSM 43827 integrase family protein YP_003097989.1 186876 R 446462 CDS YP_003097990.1 256374330 8324323 complement(188197..188499) 1 NC_013093.1 TIGRFAM: DNA binding domain protein, excisionase family; excisionase family DNA binding domain-containing protein 188499 8324323 Amir_0173 Actinosynnema mirum DSM 43827 excisionase family DNA binding domain-containing protein YP_003097990.1 188197 R 446462 CDS YP_003097991.1 256374331 8324324 complement(188496..189647) 1 NC_013093.1 KEGG: rso:RSc2483 hypothetical protein; hypothetical protein 189647 8324324 Amir_0174 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097991.1 188496 R 446462 CDS YP_003097992.1 256374332 8324325 complement(189644..190216) 1 NC_013093.1 hypothetical protein 190216 8324325 Amir_0175 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097992.1 189644 R 446462 CDS YP_003097993.1 256374333 8324326 complement(190299..190574) 1 NC_013093.1 hypothetical protein 190574 8324326 Amir_0176 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097993.1 190299 R 446462 CDS YP_003097994.1 256374334 8324327 complement(190727..192922) 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: bac:BamMC406_0006 cell divisionFtsK/SpoIIIE; cell division protein FtsK/SpoIIIE 192922 8324327 Amir_0177 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003097994.1 190727 R 446462 CDS YP_003097995.1 256374335 8324328 complement(192919..193884) 1 NC_013093.1 KEGG: bmv:BMASAVP1_A1237 hypothetical protein; hypothetical protein 193884 8324328 Amir_0178 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097995.1 192919 R 446462 CDS YP_003097996.1 256374336 8324329 complement(193881..193976) 1 NC_013093.1 hypothetical protein 193976 8324329 Amir_0179 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097996.1 193881 R 446462 CDS YP_003097997.1 256374337 8324330 complement(194069..194224) 1 NC_013093.1 hypothetical protein 194224 8324330 Amir_0180 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097997.1 194069 R 446462 CDS YP_003097998.1 256374338 8324331 complement(194253..194564) 1 NC_013093.1 hypothetical protein 194564 8324331 Amir_0181 Actinosynnema mirum DSM 43827 hypothetical protein YP_003097998.1 194253 R 446462 CDS YP_003097999.1 256374339 8324332 194728..195081 1 NC_013093.1 SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 195081 8324332 Amir_0182 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003097999.1 194728 D 446462 CDS YP_003098000.1 256374340 8324333 complement(195181..196023) 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 196023 8324333 Amir_0183 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003098000.1 195181 R 446462 CDS YP_003098001.1 256374341 8324334 196208..196987 1 NC_013093.1 PFAM: aminotransferase class IV; KEGG: smt:Smal_1152 hypothetical protein; hypothetical protein 196987 8324334 Amir_0184 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098001.1 196208 D 446462 CDS YP_003098002.1 256374342 8324335 197023..197958 1 NC_013093.1 PFAM: protein of unknown function DUF323; SMART: helix-turn-helix domain protein; KEGG: scl:sce5487 protein kinase; XRE family transcriptional regulator 197958 8324335 Amir_0185 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003098002.1 197023 D 446462 CDS YP_003098003.1 256374343 8324336 complement(198068..198250) 1 NC_013093.1 hypothetical protein 198250 8324336 Amir_0186 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098003.1 198068 R 446462 CDS YP_003098004.1 256374344 8324337 complement(198251..198898) 1 NC_013093.1 KEGG: rsq:Rsph17025_0912 hypothetical protein; hypothetical protein 198898 8324337 Amir_0187 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098004.1 198251 R 446462 CDS YP_003098005.1 256374345 8324338 complement(198895..199368) 1 NC_013093.1 KEGG: bxe:Bxe_C1257 hypothetical protein; hypothetical protein 199368 8324338 Amir_0188 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098005.1 198895 R 446462 CDS YP_003098006.1 256374346 8324339 complement(199368..200309) 1 NC_013093.1 PFAM: peptidase C14 caspase catalytic subunit p20; KEGG: bcr:BCAH187_E0055 peptidase C14 caspase catalytic subunit P20; peptidase C14 caspase catalytic subunit p20 200309 8324339 Amir_0189 Actinosynnema mirum DSM 43827 peptidase C14 caspase catalytic subunit p20 YP_003098006.1 199368 R 446462 CDS YP_003098007.1 256374347 8324340 complement(200314..200691) 1 NC_013093.1 PFAM: Domain of unknown function DUF1863; KEGG: sbm:Shew185_4383 hypothetical protein; hypothetical protein 200691 8324340 Amir_0190 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098007.1 200314 R 446462 CDS YP_003098008.1 256374348 8324341 complement(201557..202771) 1 NC_013093.1 PFAM: protein-L-isoaspartate(D-aspartate) O- methyltransferase; methyltransferase type 11; KEGG: bmj:BMULJ_02352 protein-L-isoaspartate (D- aspartate) O-methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase 202771 8324341 Amir_0191 Actinosynnema mirum DSM 43827 protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_003098008.1 201557 R 446462 CDS YP_003098009.1 256374349 8324342 complement(202768..203733) 1 NC_013093.1 KEGG: scl:sce7176 hypothetical protein; hypothetical protein 203733 8324342 Amir_0192 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098009.1 202768 R 446462 CDS YP_003098010.1 256374350 8324343 complement(203733..204038) 1 NC_013093.1 hypothetical protein 204038 8324343 Amir_0193 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098010.1 203733 R 446462 CDS YP_003098011.1 256374351 8324344 204230..205435 1 NC_013093.1 PFAM: helix-turn-helix domain protein; hypothetical protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3401 phage regulatory protein; XRE family transcriptional regulator 205435 8324344 Amir_0194 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003098011.1 204230 D 446462 CDS YP_003098012.1 256374352 8324345 206393..208858 1 NC_013093.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein; endonuclease/exonuclease/phosphatase 208858 8324345 Amir_0195 Actinosynnema mirum DSM 43827 endonuclease/exonuclease/phosphatase YP_003098012.1 206393 D 446462 CDS YP_003098013.1 256374353 8324346 complement(208921..209328) 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: scl:sce5646 hypothetical protein; endoribonuclease L-PSP 209328 8324346 Amir_0196 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003098013.1 208921 R 446462 CDS YP_003098014.1 256374354 8324347 209402..210040 1 NC_013093.1 KEGG: mlo:mlr3102 transcriptional regulator; TetR family transcriptional regulator 210040 8324347 Amir_0197 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098014.1 209402 D 446462 CDS YP_003098015.1 256374355 8324349 complement(210404..212551) 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pca:Pcar_1336 methyl-accepting chemotaxis protein (MCP); methyl-accepting chemotaxis sensory transducer 212551 8324349 Amir_0198 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003098015.1 210404 R 446462 CDS YP_003098016.1 256374356 8324350 complement(212696..214294) 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 214294 8324350 Amir_0199 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003098016.1 212696 R 446462 CDS YP_003098017.1 256374357 8324351 214464..215432 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: atc:AGR_pAT_447 DtxR/iron regulated lipoprotein precursor; periplasmic binding protein 215432 8324351 Amir_0200 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003098017.1 214464 D 446462 CDS YP_003098018.1 256374358 8324353 215613..217754 1 NC_013093.1 KEGG: gbm:Gbem_0212 DNA polymerase III subunits gamma/tau; TIGRFAM: DNA polymerase III subunits gamma/tau; PFAM: ATPase AAA; SMART: ATPase AAA; DNA polymerase III subunits gamma/tau 217754 8324353 Amir_0201 Actinosynnema mirum DSM 43827 DNA polymerase III subunits gamma/tau YP_003098018.1 215613 D 446462 CDS YP_003098019.1 256374359 8324354 217802..218149 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: gme:Gmet_3421 hypothetical protein; hypothetical protein 218149 8324354 Amir_0202 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098019.1 217802 D 446462 CDS YP_003098020.1 256374360 8324355 218149..218742 1 NC_013093.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 218742 recR 8324355 recR Actinosynnema mirum DSM 43827 recombination protein RecR YP_003098020.1 218149 D 446462 CDS YP_003098021.1 256374361 8324356 218756..219226 1 NC_013093.1 KEGG: bcz:BCZK2509 hypothetical protein; hypothetical protein 219226 8324356 Amir_0204 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098021.1 218756 D 446462 CDS YP_003098022.1 256374362 8324361 complement(225081..228347) 1 NC_013093.1 PFAM: transcriptional activator domain; TPR repeat- containing protein; hypothetical protein; NB-ARC domain protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator 228347 8324361 Amir_0205 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003098022.1 225081 R 446462 CDS YP_003098023.1 256374363 8324362 228577..230262 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: hap:HAPS_0936 periplasmic dipeptide transport protein DppA; family 5 extracellular solute-binding protein 230262 8324362 Amir_0206 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003098023.1 228577 D 446462 CDS YP_003098024.1 256374364 8324363 230308..231318 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pde:Pden_1670 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane proteint 231318 8324363 Amir_0207 Actinosynnema mirum DSM 43827 ABC transporter inner membrane proteint YP_003098024.1 230308 D 446462 CDS YP_003098025.1 256374365 8324364 231325..232257 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3642 dipeptide ABC transporter (permease); dipeptide ABC transporter permease 232257 8324364 Amir_0208 Actinosynnema mirum DSM 43827 dipeptide ABC transporter permease YP_003098025.1 231325 D 446462 CDS YP_003098026.1 256374366 8324365 232263..233258 1 NC_013093.1 KEGG: bja:bll2870 ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 233258 8324365 Amir_0209 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003098026.1 232263 D 446462 CDS YP_003098027.1 256374367 8324366 233255..234397 1 NC_013093.1 KEGG: bja:blr1357 peptide ABC transporter ATP- binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 234397 8324366 Amir_0210 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003098027.1 233255 D 446462 CDS YP_003098028.1 256374368 8324367 234560..236698 1 NC_013093.1 PFAM: N-6 DNA methylase; KEGG: xom:XOO_3262 type I restriction system adenine methylase; N-6 DNA methylase 236698 8324367 Amir_0211 Actinosynnema mirum DSM 43827 N-6 DNA methylase YP_003098028.1 234560 D 446462 CDS YP_003098029.1 256374369 8324368 237187..237762 1 NC_013093.1 KEGG: pol:Bpro_3150 DedA; membrane-associated protein 237762 8324368 Amir_0212 Actinosynnema mirum DSM 43827 membrane-associated protein YP_003098029.1 237187 D 446462 CDS YP_003098030.1 256374370 8324369 complement(237857..239653) 1 NC_013093.1 KEGG: csa:Csal_2535 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; 2-isopropylmalate synthase 239653 8324369 Amir_0213 Actinosynnema mirum DSM 43827 2-isopropylmalate synthase YP_003098030.1 237857 R 446462 CDS YP_003098031.1 256374371 8324370 239881..240186 1 NC_013093.1 hypothetical protein 240186 8324370 Amir_0214 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098031.1 239881 D 446462 CDS YP_003098032.1 256374372 8324371 complement(240214..240846) 1 NC_013093.1 PFAM: nitroreductase; KEGG: ank:AnaeK_1659 nitroreductase; nitroreductase 240846 8324371 Amir_0215 Actinosynnema mirum DSM 43827 nitroreductase YP_003098032.1 240214 R 446462 CDS YP_003098033.1 256374373 8324372 complement(240873..242096) 1 NC_013093.1 KEGG: mxa:MXAN_5370 lipoprotein; hypothetical protein 242096 8324372 Amir_0216 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098033.1 240873 R 446462 CDS YP_003098034.1 256374374 8324373 242173..243438 1 NC_013093.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 243438 8324373 Amir_0217 Actinosynnema mirum DSM 43827 aspartate kinase YP_003098034.1 242173 D 446462 CDS YP_003098035.1 256374375 8324374 243435..244502 1 NC_013093.1 KEGG: bcb:BCB4264_A3899 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase dimerization region; Semialdehyde dehydrogenase NAD - binding; aspartate-semialdehyde dehydrogenase 244502 8324374 Amir_0218 Actinosynnema mirum DSM 43827 aspartate-semialdehyde dehydrogenase YP_003098035.1 243435 D 446462 CDS YP_003098036.1 256374376 8324375 244506..245936 1 NC_013093.1 PFAM: carbohydrate kinase FGGY; KEGG: bcb:BCB4264_A2253 gluconate kinase; carbohydrate kinase FGGY 245936 8324375 Amir_0219 Actinosynnema mirum DSM 43827 carbohydrate kinase FGGY YP_003098036.1 244506 D 446462 CDS YP_003098037.1 256374377 8324376 246130..246333 1 NC_013093.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: vsa:VSAL_II0614 cold shock-like protein; cold-shock DNA-binding domain-containing protein 246333 8324376 Amir_0220 Actinosynnema mirum DSM 43827 cold-shock DNA-binding domain-containing protein YP_003098037.1 246130 D 446462 CDS YP_003098038.1 256374378 8324377 complement(246436..247614) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: ppg:PputGB1_3286 major facilitator transporter; major facilitator superfamily protein 247614 8324377 Amir_0221 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098038.1 246436 R 446462 CDS YP_003098039.1 256374379 8324378 247767..249221 1 NC_013093.1 PFAM: Catalase domain protein; KEGG: eta:ETA_17240 catalase; Catalase 249221 8324378 Amir_0222 Actinosynnema mirum DSM 43827 Catalase YP_003098039.1 247767 D 446462 CDS YP_003098040.1 256374380 8324379 249410..249832 1 NC_013093.1 PFAM: OsmC family protein; KEGG: bpy:Bphyt_6798 OsmC family protein; OsmC family protein 249832 8324379 Amir_0223 Actinosynnema mirum DSM 43827 OsmC family protein YP_003098040.1 249410 D 446462 CDS YP_003098041.1 256374381 8324380 249865..250341 1 NC_013093.1 PFAM: Ferritin Dps family protein; KEGG: mpo:Mpop_0322 ferritin Dps family protein; Ferritin Dps family protein 250341 8324380 Amir_0224 Actinosynnema mirum DSM 43827 Ferritin Dps family protein YP_003098041.1 249865 D 446462 CDS YP_003098042.1 256374382 8324381 complement(250415..250981) 1 NC_013093.1 PFAM: NADPH-dependent FMN reductase; KEGG: bpl:BURPS1106A_A1934 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 250981 8324381 Amir_0225 Actinosynnema mirum DSM 43827 NADPH-dependent FMN reductase YP_003098042.1 250415 R 446462 CDS YP_003098043.1 256374383 8324382 251061..252113 1 NC_013093.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: rce:RC1_2418 lipase; alpha/beta hydrolase fold-3 domain-containing protein 252113 8324382 Amir_0226 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold-3 domain-containing protein YP_003098043.1 251061 D 446462 CDS YP_003098044.1 256374384 8324383 complement(252213..254027) 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S15; KEGG: pzu:PHZ_c2763 dipeptidyl aminopeptidase/acylaminoacyl-peptidase; peptidase S9 prolyl oligopeptidase active site domain-containing protein 254027 8324383 Amir_0227 Actinosynnema mirum DSM 43827 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_003098044.1 252213 R 446462 CDS YP_003098045.1 256374385 8324384 complement(254024..254854) 1 NC_013093.1 PFAM: methyltransferase type 11; Cyclopropane-fatty- acyl-phospholipid synthase; methyltransferase type 12; KEGG: hha:Hhal_0984 methyltransferase type 11; type 11 methyltransferase 254854 8324384 Amir_0228 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003098045.1 254024 R 446462 CDS YP_003098046.1 256374386 8324385 complement(255115..255591) 1 NC_013093.1 SYNPO2L; KEGG: SYNPO2L; synaptopodin 2-like; synaptopodin 2-like protein 255591 8324385 Amir_0229 Actinosynnema mirum DSM 43827 synaptopodin 2-like protein YP_003098046.1 255115 R 446462 CDS YP_003098047.1 256374387 8324388 complement(256654..257529) 1 NC_013093.1 hypothetical protein 257529 8324388 Amir_0232 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098047.1 256654 R 446462 CDS YP_003098048.1 256374388 8324390 complement(258162..259121) 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: hch:HCH_04892 phosphohydrolase; metallophosphoesterase 259121 8324390 Amir_0233 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003098048.1 258162 R 446462 CDS YP_003098049.1 256374389 8324391 259185..259652 1 NC_013093.1 KEGG: mxa:MXAN_5202 GatB/YqeY domain protein; GatB/YqeY domain-containing protein 259652 8324391 Amir_0234 Actinosynnema mirum DSM 43827 GatB/YqeY domain-containing protein YP_003098049.1 259185 D 446462 CDS YP_003098050.1 256374390 8324392 complement(259758..262250) 1 NC_013093.1 PFAM: glycosyl transferase family 51; PASTA domain containing protein; penicillin-binding protein transpeptidase; SMART: PASTA domain containing protein; KEGG: azc:AZC_0337 penicillin-binding protein 1A; glycosyl transferase family protein 262250 8324392 Amir_0235 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003098050.1 259758 R 446462 CDS YP_003098051.1 256374391 8324393 262504..262797 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 262797 8324393 Amir_0236 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003098051.1 262504 D 446462 CDS YP_003098052.1 256374392 8324394 complement(262823..263947) 1 NC_013093.1 PFAM: anion-transporting ATPase; KEGG: acp:A2cp1_0984 adventurous gliding motility protein R; anion-transporting ATPase 263947 8324394 Amir_0237 Actinosynnema mirum DSM 43827 anion-transporting ATPase YP_003098052.1 262823 R 446462 CDS YP_003098053.1 256374393 8324395 complement(263944..264936) 1 NC_013093.1 PFAM: anion-transporting ATPase; KEGG: afw:Anae109_0972 chromosome partitioning-like ATPase; anion-transporting ATPase 264936 8324395 Amir_0238 Actinosynnema mirum DSM 43827 anion-transporting ATPase YP_003098053.1 263944 R 446462 CDS YP_003098054.1 256374394 8324396 complement(265300..265569) 1 NC_013093.1 hypothetical protein 265569 8324396 Amir_0239 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098054.1 265300 R 446462 CDS YP_003098055.1 256374395 8324397 266128..266283 1 NC_013093.1 hypothetical protein 266283 8324397 Amir_0240 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098055.1 266128 D 446462 CDS YP_003098056.1 256374396 8324398 266280..266738 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: rce:RC1_1921 endoribonuclease L-PSP; endoribonuclease L-PSP 266738 8324398 Amir_0241 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003098056.1 266280 D 446462 CDS YP_003098057.1 256374397 8324399 266740..267351 1 NC_013093.1 hypothetical protein 267351 8324399 Amir_0242 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098057.1 266740 D 446462 CDS YP_003098058.1 256374398 8324400 267390..268634 1 NC_013093.1 KEGG: predicted protein; hypothetical protein 268634 8324400 Amir_0243 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098058.1 267390 D 446462 CDS YP_003098059.1 256374399 8324401 complement(268651..269457) 1 NC_013093.1 KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein 269457 8324401 Amir_0244 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098059.1 268651 R 446462 CDS YP_003098060.1 256374400 8324402 complement(269454..270344) 1 NC_013093.1 PFAM: oxidoreductase domain protein; KEGG: rec:RHECIAT_PC0000780 oxidoreductase protein; oxidoreductase domain-containing protein 270344 8324402 Amir_0245 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003098060.1 269454 R 446462 CDS YP_003098061.1 256374401 8324403 complement(270356..270715) 1 NC_013093.1 hypothetical protein 270715 8324403 Amir_0246 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098061.1 270356 R 446462 CDS YP_003098062.1 256374402 8324404 270739..271578 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: rpd:RPD_3111 NUDIX hydrolase; NUDIX hydrolase 271578 8324404 Amir_0247 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003098062.1 270739 D 446462 CDS YP_003098063.1 256374403 8324405 271575..272375 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: aav:Aave_0793 beta-lactamase domain protein; beta-lactamase domain-containing protein 272375 8324405 Amir_0248 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003098063.1 271575 D 446462 CDS YP_003098064.1 256374404 8324406 272493..273131 1 NC_013093.1 KEGG: mlo:mlr3017 5'-nucleotidase; hypothetical protein 273131 8324406 Amir_0249 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098064.1 272493 D 446462 CDS YP_003098065.1 256374405 8324407 complement(273148..273483) 1 NC_013093.1 hypothetical protein 273483 8324407 Amir_0250 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098065.1 273148 R 446462 CDS YP_003098066.1 256374406 8324408 complement(273605..274702) 1 NC_013093.1 KEGG: sus:Acid_0002 DNA polymerase III subunit beta; TIGRFAM: DNA polymerase III subunit beta; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain; DNA polymerase III subunit beta 274702 8324408 Amir_0251 Actinosynnema mirum DSM 43827 DNA polymerase III subunit beta YP_003098066.1 273605 R 446462 CDS YP_003098067.1 256374407 8324409 complement(274744..276042) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: sml:Smlt0548 MFS family transporter; major facilitator superfamily protein 276042 8324409 Amir_0252 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098067.1 274744 R 446462 CDS YP_003098068.1 256374408 8324410 complement(276747..277421) 1 NC_013093.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: bbt:BBta_5745 transcriptional regulator; Crp/Fnr family transcriptional regulator 277421 8324410 Amir_0253 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003098068.1 276747 R 446462 CDS YP_003098069.1 256374409 8324411 complement(277624..277872) 1 NC_013093.1 hypothetical protein 277872 8324411 Amir_0254 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098069.1 277624 R 446462 CDS YP_003098070.1 256374410 8324412 278144..278917 1 NC_013093.1 KEGG: pca:Pcar_0009 endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop; endonuclease III 278917 8324412 Amir_0255 Actinosynnema mirum DSM 43827 endonuclease III YP_003098070.1 278144 D 446462 CDS YP_003098071.1 256374411 8324413 278914..279594 1 NC_013093.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: xop:PXO_04554 thioredoxin; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 279594 8324413 Amir_0256 Actinosynnema mirum DSM 43827 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_003098071.1 278914 D 446462 CDS YP_003098072.1 256374412 8324414 279591..280331 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: mch:Mchl_1739 NUDIX hydrolase; NUDIX hydrolase 280331 8324414 Amir_0257 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003098072.1 279591 D 446462 CDS YP_003098073.1 256374413 8324415 280353..281540 1 NC_013093.1 PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; Colicin V production protein 281540 8324415 Amir_0258 Actinosynnema mirum DSM 43827 Colicin V production protein YP_003098073.1 280353 D 446462 CDS YP_003098074.1 256374414 8324416 complement(281588..282514) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: acp:A2cp1_0551 alpha/beta hydrolase fold protein; alpha/beta hydrolase fold protein 282514 8324416 Amir_0259 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003098074.1 281588 R 446462 CDS YP_003098075.1 256374415 8324417 complement(282523..282990) 1 NC_013093.1 PFAM: protein of unknown function DUF1469; KEGG: mpo:Mpop_1689 protein of unknown function DUF1469; hypothetical protein 282990 8324417 Amir_0260 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098075.1 282523 R 446462 CDS YP_003098076.1 256374416 8324418 complement(283062..284234) 1 NC_013093.1 TIGRFAM: Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter NhaA; sodium/hydrogen exchanger; KEGG: mlo:mlr5309 Na+/H+ antiporter; Na+/H+ antiporter NhaA 284234 8324418 Amir_0261 Actinosynnema mirum DSM 43827 Na+/H+ antiporter NhaA YP_003098076.1 283062 R 446462 CDS YP_003098077.1 256374417 8324419 complement(284370..286355) 1 NC_013093.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 286355 8324419 Amir_0262 Actinosynnema mirum DSM 43827 acetyl-CoA synthetase YP_003098077.1 284370 R 446462 CDS YP_003098078.1 256374418 8324420 complement(286579..287160) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aav:Aave_3953 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 287160 8324420 Amir_0263 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003098078.1 286579 R 446462 CDS YP_003098079.1 256374419 8324421 287252..287974 1 NC_013093.1 KEGG: mxa:MXAN_6904 hypothetical protein; hypothetical protein 287974 8324421 Amir_0264 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098079.1 287252 D 446462 CDS YP_003098080.1 256374420 8324422 complement(287971..289092) 1 NC_013093.1 TIGRFAM: kynureninase; PFAM: aminotransferase class V; KEGG: pde:Pden_2620 kynureninase; kynureninase 289092 8324422 Amir_0265 Actinosynnema mirum DSM 43827 kynureninase YP_003098080.1 287971 R 446462 CDS YP_003098081.1 256374421 8324423 complement(289089..289910) 1 NC_013093.1 PFAM: tryptophan 23-dioxygenase; KEGG: reh:H16_B1418 tryptophan 2,3-dioxygenase; tryptophan 23-dioxygenase 289910 8324423 Amir_0266 Actinosynnema mirum DSM 43827 tryptophan 23-dioxygenase YP_003098081.1 289089 R 446462 CDS YP_003098082.1 256374422 8324424 290017..290466 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: bam:Bamb_3888 AsnC family transcriptional regulator; AsnC family transcriptional regulator 290466 8324424 Amir_0267 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003098082.1 290017 D 446462 CDS YP_003098083.1 256374423 8324425 complement(290435..291361) 1 NC_013093.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 291361 murQ 8324425 murQ Actinosynnema mirum DSM 43827 N-acetylmuramic acid-6-phosphate etherase YP_003098083.1 290435 R 446462 CDS YP_003098084.1 256374424 8324426 complement(291358..292272) 1 NC_013093.1 PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: reh:H16_B1066 transcriptional regulator; RpiR family transcriptional regulator 292272 8324426 Amir_0269 Actinosynnema mirum DSM 43827 RpiR family transcriptional regulator YP_003098084.1 291358 R 446462 CDS YP_003098085.1 256374425 8324427 complement(292383..294536) 1 NC_013093.1 PFAM: beta-lactamase; KEGG: beta-lactamase; beta-lactamase 294536 8324427 Amir_0270 Actinosynnema mirum DSM 43827 beta-lactamase YP_003098085.1 292383 R 446462 CDS YP_003098086.1 256374426 8324428 complement(294549..295880) 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: hypothetical protein; hypothetical protein 295880 8324428 Amir_0271 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098086.1 294549 R 446462 CDS YP_003098087.1 256374427 8324429 complement(295935..296138) 1 NC_013093.1 KEGG: similar to mucin 17; hypothetical protein 296138 8324429 Amir_0272 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098087.1 295935 R 446462 CDS YP_003098088.1 256374428 8324430 complement(296355..298097) 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: bha:BH0675 beta-hexosamidase A precursor; glycoside hydrolase family protein 298097 8324430 Amir_0273 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003098088.1 296355 R 446462 CDS YP_003098089.1 256374429 8324431 complement(298682..299494) 1 NC_013093.1 TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase- like); KEGG: pap:PSPA7_0428 hypothetical protein; HAD superfamily hydrolase 299494 8324431 Amir_0274 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003098089.1 298682 R 446462 CDS YP_003098090.1 256374430 8324432 299900..301015 1 NC_013093.1 KEGG: ank:AnaeK_2914 Flp pilus assembly protein ATPase CpaE-like protein; hypothetical protein 301015 8324432 Amir_0275 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098090.1 299900 D 446462 CDS YP_003098091.1 256374431 8324433 301321..302439 1 NC_013093.1 PFAM: type II secretion system protein E; KEGG: bav:BAV2285 pilus assembly protein; type II secretion system protein E 302439 8324433 Amir_0276 Actinosynnema mirum DSM 43827 type II secretion system protein E YP_003098091.1 301321 D 446462 CDS YP_003098092.1 256374432 8324434 302579..303334 1 NC_013093.1 PFAM: type II secretion system protein; KEGG: acp:A2cp1_3010 type II secretion system protein; type II secretion system protein 303334 8324434 Amir_0277 Actinosynnema mirum DSM 43827 type II secretion system protein YP_003098092.1 302579 D 446462 CDS YP_003098093.1 256374433 8324435 303331..303888 1 NC_013093.1 PFAM: type II secretion system protein; KEGG: Hcn2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; K04955 hyperpolarization activated cyclic nucleotide-gated potassium channel 2; type II secretion system protein 303888 8324435 Amir_0278 Actinosynnema mirum DSM 43827 type II secretion system protein YP_003098093.1 303331 D 446462 CDS YP_003098094.1 256374434 8324436 303910..304065 1 NC_013093.1 hypothetical protein 304065 8324436 Amir_0279 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098094.1 303910 D 446462 CDS YP_003098095.1 256374435 8324437 304062..304478 1 NC_013093.1 hypothetical protein 304478 8324437 Amir_0280 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098095.1 304062 D 446462 CDS YP_003098096.1 256374436 8324438 304605..304934 1 NC_013093.1 KEGG: nwi:Nwi_2535 hypothetical protein; hypothetical protein 304934 8324438 Amir_0281 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098096.1 304605 D 446462 CDS YP_003098097.1 256374437 8324439 305305..305910 1 NC_013093.1 PFAM: Bifunctional DNA primase/polymerase; Bifunctional DNA primase/polymerase 305910 8324439 Amir_0282 Actinosynnema mirum DSM 43827 Bifunctional DNA primase/polymerase YP_003098097.1 305305 D 446462 CDS YP_003098098.1 256374438 8324440 complement(306276..308699) 1 NC_013093.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: dvu:DVU0256 DEAD-box ATP dependent DNA helicase; DEAD/DEAH box helicase domain-containing protein 308699 8324440 Amir_0283 Actinosynnema mirum DSM 43827 DEAD/DEAH box helicase domain-containing protein YP_003098098.1 306276 R 446462 CDS YP_003098099.1 256374439 8324441 308935..311295 1 NC_013093.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 311295 hppA 8324441 hppA Actinosynnema mirum DSM 43827 membrane-bound proton-translocating pyrophosphatase YP_003098099.1 308935 D 446462 CDS YP_003098100.1 256374440 8324442 311416..312054 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 312054 8324442 Amir_0285 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098100.1 311416 D 446462 CDS YP_003098101.1 256374441 8324443 312083..312202 1 NC_013093.1 hypothetical protein 312202 8324443 Amir_0286 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098101.1 312083 D 446462 CDS YP_003098102.1 256374442 8324444 312321..312962 1 NC_013093.1 KEGG: bac:BamMC406_1732 peptidase M23; hypothetical protein 312962 8324444 Amir_0287 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098102.1 312321 D 446462 CDS YP_003098103.1 256374443 8324445 313088..313771 1 NC_013093.1 KEGG: YALI0D24365p; hypothetical protein 313771 8324445 Amir_0288 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098103.1 313088 D 446462 CDS YP_003098104.1 256374444 8324446 313913..314566 1 NC_013093.1 KEGG: mucin-associated surface protein (MASP); hypothetical protein 314566 8324446 Amir_0289 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098104.1 313913 D 446462 CDS YP_003098105.1 256374445 8324447 314696..315328 1 NC_013093.1 KEGG: swi:Swit_0780 branched-chain alpha-keto acid dehydrogenase E2 component; hypothetical protein 315328 8324447 Amir_0290 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098105.1 314696 D 446462 CDS YP_003098106.1 256374446 8324448 315457..318228 1 NC_013093.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 318228 8324448 Amir_0291 Actinosynnema mirum DSM 43827 DNA topoisomerase I YP_003098106.1 315457 D 446462 CDS YP_003098107.1 256374447 8324449 318252..318821 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 318821 8324449 Amir_0292 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098107.1 318252 D 446462 CDS YP_003098108.1 256374448 8324450 318901..321033 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; thymidylate kinase; KEGG: eli:ELI_06215 thymidylate kinase; major facilitator superfamily protein 321033 8324450 Amir_0293 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098108.1 318901 D 446462 CDS YP_003098109.1 256374449 8324451 321047..322246 1 NC_013093.1 KEGG: dal:Dalk_0024 DNA-directed DNA polymerase; DNA-directed DNA polymerase 322246 8324451 Amir_0294 Actinosynnema mirum DSM 43827 DNA-directed DNA polymerase YP_003098109.1 321047 D 446462 CDS YP_003098110.1 256374450 8324453 322756..323649 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: dal:Dalk_4823 glycosyl transferase family 2; family 2 glycosyl transferase 323649 8324453 Amir_0295 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003098110.1 322756 D 446462 CDS YP_003098111.1 256374451 8324454 complement(323703..325736) 1 NC_013093.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 325736 8324454 Amir_0296 Actinosynnema mirum DSM 43827 iron-hydroxamate transporter permease subunit YP_003098111.1 323703 R 446462 CDS YP_003098112.1 256374452 8324455 complement(325736..326707) 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: bcb:BCB4264_A4636 iron compound ABC transporter, iron compound-binding protein; periplasmic binding protein 326707 8324455 Amir_0297 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003098112.1 325736 R 446462 CDS YP_003098113.1 256374453 8324456 complement(326738..327556) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ent:Ent638_1120 iron-enterobactin transporter ATP-binding protein; ABC transporter 327556 8324456 Amir_0298 Actinosynnema mirum DSM 43827 ABC transporter YP_003098113.1 326738 R 446462 CDS YP_003098114.1 256374454 8324457 328007..328162 1 NC_013093.1 hypothetical protein 328162 8324457 Amir_0299 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098114.1 328007 D 446462 CDS YP_003098115.1 256374455 8324458 complement(328149..329243) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: swi:Swit_1615 coenzyme F420-dependent N5 N10- methylene tetrahydromethanopterin reductase-like protein; luciferase-like monooxygenase 329243 8324458 Amir_0300 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003098115.1 328149 R 446462 CDS YP_003098116.1 256374456 8324459 complement(329240..329704) 1 NC_013093.1 PFAM: Excalibur domain protein; KEGG: GE20613 gene product from transcript GE20613- RA; Excalibur domain-containing protein 329704 8324459 Amir_0301 Actinosynnema mirum DSM 43827 Excalibur domain-containing protein YP_003098116.1 329240 R 446462 CDS YP_003098117.1 256374457 8324460 complement(329694..330653) 1 NC_013093.1 PFAM: Excalibur domain protein; KEGG: sal:Sala_0134 excalibur; Excalibur domain-containing protein 330653 8324460 Amir_0302 Actinosynnema mirum DSM 43827 Excalibur domain-containing protein YP_003098117.1 329694 R 446462 CDS YP_003098118.1 256374458 8324461 complement(330650..331321) 1 NC_013093.1 PFAM: nuclease (SNase domain protein); SMART: nuclease (SNase domain protein); KEGG: mno:Mnod_4939 hypothetical protein; nuclease 331321 8324461 Amir_0303 Actinosynnema mirum DSM 43827 nuclease YP_003098118.1 330650 R 446462 CDS YP_003098119.1 256374459 8324462 complement(331443..331889) 1 NC_013093.1 KEGG: pzu:PHZ_c1913 hypothetical protein; hypothetical protein 331889 8324462 Amir_0304 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098119.1 331443 R 446462 CDS YP_003098120.1 256374460 8324463 332019..332537 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: atc:AGR_C_1531 hypothetical protein; MarR family transcriptional regulator 332537 8324463 Amir_0305 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003098120.1 332019 D 446462 CDS YP_003098121.1 256374461 8324464 332537..334204 1 NC_013093.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ppg:PputGB1_3285 EmrB/QacA family drug resistance transporter; EmrB/QacA subfamily drug resistance transporter 334204 8324464 Amir_0306 Actinosynnema mirum DSM 43827 EmrB/QacA subfamily drug resistance transporter YP_003098121.1 332537 D 446462 CDS YP_003098122.1 256374462 8324465 complement(334313..334816) 1 NC_013093.1 PFAM: inorganic pyrophosphatase; KEGG: gdi:GDI3491 inorganic pyrophosphatase; inorganic diphosphatase 334816 8324465 Amir_0307 Actinosynnema mirum DSM 43827 inorganic diphosphatase YP_003098122.1 334313 R 446462 CDS YP_003098123.1 256374463 8324466 334943..337993 1 NC_013093.1 TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D- alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; KEGG: bpm:BURPS1710b_1102 lipoprotein; D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D- alanine-endopeptidase 337993 8324466 Amir_0308 Actinosynnema mirum DSM 43827 D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D- alanine-endopeptidase YP_003098123.1 334943 D 446462 CDS YP_003098124.1 256374464 8324467 338032..339045 1 NC_013093.1 hypothetical protein 339045 8324467 Amir_0309 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098124.1 338032 D 446462 CDS YP_003098125.1 256374465 8324468 339042..339968 1 NC_013093.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: ade:Adeh_1494 tRNA(Ile)-lysidine synthetase- like; tRNA(Ile)-lysidine synthetase 339968 8324468 Amir_0310 Actinosynnema mirum DSM 43827 tRNA(Ile)-lysidine synthetase YP_003098125.1 339042 D 446462 CDS YP_003098126.1 256374466 8324469 339985..340533 1 NC_013093.1 KEGG: spe:Spro_3998 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 340533 8324469 Amir_0311 Actinosynnema mirum DSM 43827 hypoxanthine phosphoribosyltransferase YP_003098126.1 339985 D 446462 CDS YP_003098127.1 256374467 8324470 complement(340597..342291) 1 NC_013093.1 PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: dac:Daci_0766 von Willebrand factor type A; von Willebrand factor type A 342291 8324470 Amir_0312 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003098127.1 340597 R 446462 CDS YP_003098128.1 256374468 8324471 342757..344988 1 NC_013093.1 KEGG: bcy:Bcer98_0060 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; peptidase M41 FtsH extracellular; ATPase AAA; SMART: ATPase AAA; ATP-dependent metalloprotease FtsH 344988 8324471 Amir_0313 Actinosynnema mirum DSM 43827 ATP-dependent metalloprotease FtsH YP_003098128.1 342757 D 446462 CDS YP_003098129.1 256374469 8324472 344985..345614 1 NC_013093.1 KEGG: bha:BH1646 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; GTP cyclohydrolase I 345614 8324472 Amir_0314 Actinosynnema mirum DSM 43827 GTP cyclohydrolase I YP_003098129.1 344985 D 446462 CDS YP_003098130.1 256374470 8324473 345653..346438 1 NC_013093.1 KEGG: afw:Anae109_2337 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; dihydropteroate synthase 346438 8324473 Amir_0315 Actinosynnema mirum DSM 43827 dihydropteroate synthase YP_003098130.1 345653 D 446462 CDS YP_003098131.1 256374471 8324474 346431..346808 1 NC_013093.1 TIGRFAM: dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase; KEGG: oca:OCAR_6643 dihydroneopterin aldolase; dihydroneopterin aldolase 346808 8324474 Amir_0316 Actinosynnema mirum DSM 43827 dihydroneopterin aldolase YP_003098131.1 346431 D 446462 CDS YP_003098132.1 256374472 8324475 346805..347281 1 NC_013093.1 KEGG: mex:Mext_1812 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase 347281 8324475 Amir_0317 Actinosynnema mirum DSM 43827 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase YP_003098132.1 346805 D 446462 CDS YP_003098133.1 256374473 8324476 347278..347730 1 NC_013093.1 KEGG: afw:Anae109_2860 cytochrome C oxidase subunit III; hypothetical protein 347730 8324476 Amir_0318 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098133.1 347278 D 446462 CDS YP_003098134.1 256374474 8324477 347781..349451 1 NC_013093.1 KEGG: mgm:Mmc1_2162 hypothetical protein; hypothetical protein 349451 8324477 Amir_0319 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098134.1 347781 D 446462 CDS YP_003098135.1 256374475 8324478 complement(349936..351012) 1 NC_013093.1 PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: bcz:BCZK4997 NADH dehydrogenase subunit D; NADH dehydrogenase (quinone) 351012 8324478 Amir_0320 Actinosynnema mirum DSM 43827 NADH dehydrogenase (quinone) YP_003098135.1 349936 R 446462 CDS YP_003098136.1 256374476 8324479 complement(351017..351454) 1 NC_013093.1 PFAM: protein of unknown function DUF1203; KEGG: rle:RL1972 hypothetical protein; hypothetical protein 351454 8324479 Amir_0321 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098136.1 351017 R 446462 CDS YP_003098137.1 256374477 8324480 351540..352457 1 NC_013093.1 PFAM: protein of unknown function DUF185; KEGG: lch:Lcho_0104 hypothetical protein; hypothetical protein 352457 8324480 Amir_0322 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098137.1 351540 D 446462 CDS YP_003098138.1 256374478 8324481 352527..353855 1 NC_013093.1 KEGG: scl:sce5075 hypothetical protein; hypothetical protein 353855 8324481 Amir_0323 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098138.1 352527 D 446462 CDS YP_003098139.1 256374479 8324482 353944..354837 1 NC_013093.1 KEGG: sat:SYN_02774 cytoplasmic protein; cytoplasmic protein 354837 8324482 Amir_0324 Actinosynnema mirum DSM 43827 cytoplasmic protein YP_003098139.1 353944 D 446462 CDS YP_003098140.1 256374480 8324483 354841..355731 1 NC_013093.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 355731 panC 8324483 panC Actinosynnema mirum DSM 43827 pantoate--beta-alanine ligase YP_003098140.1 354841 D 446462 CDS YP_003098141.1 256374481 8324484 355746..356216 1 NC_013093.1 KEGG: bcb:BCB4264_A1597 aspartate 1-decarboxylase; TIGRFAM: aspartate 1-decarboxylase; PFAM: aspartate decarboxylase; aspartate 1-decarboxylase 356216 8324484 Amir_0326 Actinosynnema mirum DSM 43827 aspartate 1-decarboxylase YP_003098141.1 355746 D 446462 CDS YP_003098142.1 256374482 8324485 356227..357012 1 NC_013093.1 TIGRFAM: transcriptional activator, Baf family; PFAM: Bvg accessory factor; KEGG: ank:AnaeK_1477 transcriptional acitvator, Baf family; transcriptional acitvator, Baf family 357012 8324485 Amir_0327 Actinosynnema mirum DSM 43827 transcriptional acitvator, Baf family YP_003098142.1 356227 D 446462 CDS YP_003098143.1 256374483 8324486 complement(357087..357866) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mno:Mnod_8065 methyltransferase type 11; type 11 methyltransferase 357866 8324486 Amir_0328 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003098143.1 357087 R 446462 CDS YP_003098144.1 256374484 8324487 357929..359440 1 NC_013093.1 TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dal:Dalk_1784 lysyl-tRNA synthetase; lysyl-tRNA synthetase 359440 8324487 Amir_0329 Actinosynnema mirum DSM 43827 lysyl-tRNA synthetase YP_003098144.1 357929 D 446462 CDS YP_003098145.1 256374485 8324488 359559..359909 1 NC_013093.1 hypothetical protein 359909 8324488 Amir_0330 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098145.1 359559 D 446462 CDS YP_003098146.1 256374486 8324489 360226..361230 1 NC_013093.1 PFAM: transport system permease protein; KEGG: pde:Pden_3523 transport system permease protein; transport system permease 361230 8324489 Amir_0331 Actinosynnema mirum DSM 43827 transport system permease YP_003098146.1 360226 D 446462 CDS YP_003098147.1 256374487 8324490 361227..362411 1 NC_013093.1 PFAM: transport system permease protein; KEGG: ppg:PputGB1_1806 transport system permease protein; transport system permease 362411 8324490 Amir_0332 Actinosynnema mirum DSM 43827 transport system permease YP_003098147.1 361227 D 446462 CDS YP_003098148.1 256374488 8324491 362408..363256 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cvi:CV_2234 enterobactin-iron transport system ATP-binding protein; ABC transporter 363256 8324491 Amir_0333 Actinosynnema mirum DSM 43827 ABC transporter YP_003098148.1 362408 D 446462 CDS YP_003098149.1 256374489 8324492 complement(363284..364099) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 364099 8324492 Amir_0334 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098149.1 363284 R 446462 CDS YP_003098150.1 256374490 8324493 364370..366928 1 NC_013093.1 PFAM: ATPase AAA; ATPase AAA; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA; KEGG: bha:BH0103 class III stress response-related ATPase; ATPase AAA 366928 8324493 Amir_0335 Actinosynnema mirum DSM 43827 ATPase AAA YP_003098150.1 364370 D 446462 CDS YP_003098151.1 256374491 8324494 complement(367074..367718) 1 NC_013093.1 KEGG: saz:Sama_0018 pyroglutamyl-peptidase I; TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15 pyroglutamyl peptidase I; pyrrolidone-carboxylate peptidase 367718 8324494 Amir_0336 Actinosynnema mirum DSM 43827 pyrrolidone-carboxylate peptidase YP_003098151.1 367074 R 446462 CDS YP_003098152.1 256374492 8324495 367737..368708 1 NC_013093.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: afw:Anae109_1227 endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 368708 8324495 Amir_0337 Actinosynnema mirum DSM 43827 endonuclease/exonuclease/phosphatase YP_003098152.1 367737 D 446462 CDS YP_003098153.1 256374493 8324496 complement(368769..369539) 1 NC_013093.1 PFAM: Silent information regulator protein Sir2; KEGG: afw:Anae109_4302 silent information regulator protein Sir2; Silent information regulator protein Sir2 369539 8324496 Amir_0338 Actinosynnema mirum DSM 43827 Silent information regulator protein Sir2 YP_003098153.1 368769 R 446462 CDS YP_003098154.1 256374494 8324497 complement(369553..369864) 1 NC_013093.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: afr:AFE_2662 antibiotic biosynthesis monooxygenase family protein; Antibiotic biosynthesis monooxygenase 369864 8324497 Amir_0339 Actinosynnema mirum DSM 43827 Antibiotic biosynthesis monooxygenase YP_003098154.1 369553 R 446462 CDS YP_003098155.1 256374495 8324498 complement(369874..371352) 1 NC_013093.1 PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: mxa:MXAN_0644 peptidase, M1 (aminopeptidase N) family; peptidase M1 membrane alanine aminopeptidase 371352 8324498 Amir_0340 Actinosynnema mirum DSM 43827 peptidase M1 membrane alanine aminopeptidase YP_003098155.1 369874 R 446462 CDS YP_003098156.1 256374496 8324499 371370..372116 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: ppg:PputGB1_4047 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 372116 8324499 Amir_0341 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003098156.1 371370 D 446462 CDS YP_003098157.1 256374497 8324500 complement(372065..372571) 1 NC_013093.1 hypothetical protein 372571 8324500 Amir_0342 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098157.1 372065 R 446462 CDS YP_003098158.1 256374498 8324501 complement(372629..373618) 1 NC_013093.1 PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; KEGG: scl:sce3935 A/G-specific adenine glycosylase; HhH-GPD family protein 373618 8324501 Amir_0343 Actinosynnema mirum DSM 43827 HhH-GPD family protein YP_003098158.1 372629 R 446462 CDS YP_003098159.1 256374499 8324502 complement(373677..374168) 1 NC_013093.1 PFAM: carbonic anhydrase; KEGG: aba:Acid345_1601 carbonic anhydrase; carbonic anhydrase 374168 8324502 Amir_0344 Actinosynnema mirum DSM 43827 carbonic anhydrase YP_003098159.1 373677 R 446462 CDS YP_003098160.1 256374500 8324503 374248..375048 1 NC_013093.1 KEGG: hypothetical protein; K05747 Wiskott-Aldrich syndrome protein; hypothetical protein 375048 8324503 Amir_0345 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098160.1 374248 D 446462 CDS YP_003098161.1 256374501 8324504 complement(375152..376255) 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: gox:GOX0577 transcriptional regulator; LacI family transcriptional regulator 376255 8324504 Amir_0346 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003098161.1 375152 R 446462 CDS YP_003098162.1 256374502 8324505 complement(376377..377420) 1 NC_013093.1 KEGG: pen:PSEEN1955 ribose operon repressor RbsR; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 377420 8324505 Amir_0347 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003098162.1 376377 R 446462 CDS YP_003098163.1 256374503 8324506 377686..378945 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: oan:Oant_3895 extracellular solute-binding protein family 1; family 1 extracellular solute-binding protein 378945 8324506 Amir_0348 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003098163.1 377686 D 446462 CDS YP_003098164.1 256374504 8324507 379013..379930 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ade:Adeh_4135 ABC sugar transporter, inner membrane subunit; sugar ABC transporter inner membrane protein 379930 8324507 Amir_0349 Actinosynnema mirum DSM 43827 sugar ABC transporter inner membrane protein YP_003098164.1 379013 D 446462 CDS YP_003098165.1 256374505 8324508 379930..380823 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: acp:A2cp1_4287 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 380823 8324508 Amir_0350 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098165.1 379930 D 446462 CDS YP_003098166.1 256374506 8324509 380907..382007 1 NC_013093.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: rlt:Rleg2_5484 ABC transporter; ABC transporter 382007 8324509 Amir_0351 Actinosynnema mirum DSM 43827 ABC transporter YP_003098166.1 380907 D 446462 CDS YP_003098167.1 256374507 8324510 382167..383057 1 NC_013093.1 PFAM: periplasmic solute binding protein; KEGG: bpy:Bphyt_0292 periplasmic solute binding protein; periplasmic solute binding protein 383057 8324510 Amir_0352 Actinosynnema mirum DSM 43827 periplasmic solute binding protein YP_003098167.1 382167 D 446462 CDS YP_003098168.1 256374508 8324511 383054..383896 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bvi:Bcep1808_2715 ABC transporter; ABC transporter 383896 8324511 Amir_0353 Actinosynnema mirum DSM 43827 ABC transporter YP_003098168.1 383054 D 446462 CDS YP_003098169.1 256374509 8324512 383896..384732 1 NC_013093.1 PFAM: ABC transporter; KEGG: bxe:Bxe_A0715 ABC Mn2+/Zn2+ transporter, inner membrane subunit; ABC transporter 384732 8324512 Amir_0354 Actinosynnema mirum DSM 43827 ABC transporter YP_003098169.1 383896 D 446462 CDS YP_003098170.1 256374510 8324513 complement(384876..386333) 1 NC_013093.1 KEGG: cvi:CV_3252 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 386333 8324513 Amir_0355 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003098170.1 384876 R 446462 CDS YP_003098171.1 256374511 8324514 complement(386565..387788) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: reh:H16_B2569 MFS transporter; major facilitator superfamily protein 387788 8324514 Amir_0356 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098171.1 386565 R 446462 CDS YP_003098172.1 256374512 8324515 388223..388399 1 NC_013093.1 hypothetical protein 388399 8324515 Amir_0357 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098172.1 388223 D 446462 CDS YP_003098173.1 256374513 8324516 complement(388670..390100) 1 NC_013093.1 PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: ppw:PputW619_0881 membrane bound O-acyl transferase MBOAT family protein; membrane bound O-acyl transferase MBOAT family protein 390100 8324516 Amir_0358 Actinosynnema mirum DSM 43827 membrane bound O-acyl transferase MBOAT family protein YP_003098173.1 388670 R 446462 CDS YP_003098174.1 256374514 8324517 complement(390193..391158) 1 NC_013093.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: afw:Anae109_2230 RNA methyltransferase; TrmH family RNA methyltransferase 391158 8324517 Amir_0359 Actinosynnema mirum DSM 43827 TrmH family RNA methyltransferase YP_003098174.1 390193 R 446462 CDS YP_003098175.1 256374515 8324518 complement(391164..392558) 1 NC_013093.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 392558 cysS 8324518 cysS Actinosynnema mirum DSM 43827 cysteinyl-tRNA synthetase YP_003098175.1 391164 R 446462 CDS YP_003098176.1 256374516 8324519 complement(392625..393236) 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: haloacid dehalogenase-like hydrolase family protein; HAD superfamily hydrolase 393236 8324519 Amir_0361 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003098176.1 392625 R 446462 CDS YP_003098177.1 256374517 8324520 complement(393471..393938) 1 NC_013093.1 KEGG: eli:ELI_06290 bifunctional 2-C-methyl-D- erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D- erythritol 2,4-cyclodiphosphate synthase protein; TIGRFAM: 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase; PFAM: MECDP-synthase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 393938 8324520 Amir_0362 Actinosynnema mirum DSM 43827 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_003098177.1 393471 R 446462 CDS YP_003098178.1 256374518 8324521 complement(393935..394627) 1 NC_013093.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: bcr:BCAH187_A0116 2-C-methyl-D-erythritol 4- phosphate cytidylyltransferase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 394627 8324521 Amir_0363 Actinosynnema mirum DSM 43827 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_003098178.1 393935 R 446462 CDS YP_003098179.1 256374519 8324522 complement(394663..395151) 1 NC_013093.1 PFAM: transcription factor CarD; KEGG: bcb:BCB4264_A4827 transcriptional regulator, CarD family; CarD family transcriptional regulator 395151 8324522 Amir_0364 Actinosynnema mirum DSM 43827 CarD family transcriptional regulator YP_003098179.1 394663 R 446462 CDS YP_003098180.1 256374520 8324523 395536..396153 1 NC_013093.1 KEGG: YALI0C03894p; hypothetical protein 396153 8324523 Amir_0365 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098180.1 395536 D 446462 CDS YP_003098181.1 256374521 8324524 396591..397979 1 NC_013093.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 397979 8324524 Amir_0366 Actinosynnema mirum DSM 43827 DNA repair protein RadA YP_003098181.1 396591 D 446462 CDS YP_003098182.1 256374522 8324525 complement(398370..399224) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: bur:Bcep18194_B2467 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 399224 8324525 Amir_0367 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003098182.1 398370 R 446462 CDS YP_003098183.1 256374523 8324526 399383..400234 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: reh:H16_B1910 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 400234 8324526 Amir_0368 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003098183.1 399383 D 446462 CDS YP_003098184.1 256374524 8324528 complement(400639..403167) 1 NC_013093.1 TIGRFAM: trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; PFAM: glycoside hydrolase 15-related; trehalose- phosphatase; KEGG: nmu:Nmul_A2309 glycoside hydrolase 15-like protein; trehalose-phosphatase 403167 8324528 Amir_0370 Actinosynnema mirum DSM 43827 trehalose-phosphatase YP_003098184.1 400639 R 446462 CDS YP_003098185.1 256374525 8324529 complement(403246..404682) 1 NC_013093.1 PFAM: glycosyl transferase family 20; KEGG: scl:sce0488 alpha,alpha-trehalose-phosphate synthase (UDP-forming); alpha,alpha-trehalose-phosphate synthase 404682 8324529 Amir_0371 Actinosynnema mirum DSM 43827 alpha,alpha-trehalose-phosphate synthase YP_003098185.1 403246 R 446462 CDS YP_003098186.1 256374526 8324530 complement(404791..406185) 1 NC_013093.1 PFAM: protein of unknown function DUF1212; KEGG: rpt:Rpal_1546 protein of unknown function DUF1212; hypothetical protein 406185 8324530 Amir_0372 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098186.1 404791 R 446462 CDS YP_003098187.1 256374527 8324533 407108..408085 1 NC_013093.1 SMART: regulatory protein ArsR; KEGG: ajs:Ajs_2855 ArsR family transcriptional regulator; ArsR family transcriptional regulator 408085 8324533 Amir_0374 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003098187.1 407108 D 446462 CDS YP_003098188.1 256374528 8324534 complement(408188..409822) 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 409822 8324534 Amir_0375 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003098188.1 408188 R 446462 CDS YP_003098189.1 256374529 8324535 complement(409989..411551) 1 NC_013093.1 PFAM: chemotaxis sensory transducer; GAF domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer with GAF sensor 411551 8324535 Amir_0376 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer with GAF sensor YP_003098189.1 409989 R 446462 CDS YP_003098190.1 256374530 8324536 complement(411724..413376) 1 NC_013093.1 PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: mxa:MXAN_6334 hypothetical protein; von Willebrand factor type A 413376 8324536 Amir_0377 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003098190.1 411724 R 446462 CDS YP_003098191.1 256374531 8324537 complement(413875..415284) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase 415284 8324537 Amir_0378 Actinosynnema mirum DSM 43827 histidine kinase YP_003098191.1 413875 R 446462 CDS YP_003098192.1 256374532 8324538 complement(415284..415985) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bat:BAS2056 DNA-binding response regulator; winged helix family two component transcriptional regulator 415985 8324538 Amir_0379 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003098192.1 415284 R 446462 CDS YP_003098193.1 256374533 8324539 416139..417482 1 NC_013093.1 PFAM: Ferric reductase domain protein transmembrane component domain; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; FAD-binding 8 domain protein; KEGG: ank:AnaeK_0310 oxidoreductase FAD/NAD(P)- binding domain protein; ferric reductase transmembrane domain-containing protein 417482 8324539 Amir_0380 Actinosynnema mirum DSM 43827 ferric reductase transmembrane domain-containing protein YP_003098193.1 416139 D 446462 CDS YP_003098194.1 256374534 8324540 417520..417927 1 NC_013093.1 PFAM: FMN-binding domain protein; KEGG: mlo:mll6621 hypothetical protein; FMN-binding domain-containing protein 417927 8324540 Amir_0381 Actinosynnema mirum DSM 43827 FMN-binding domain-containing protein YP_003098194.1 417520 D 446462 CDS YP_003098195.1 256374535 8324541 417932..418645 1 NC_013093.1 PFAM: ApbE family lipoprotein; KEGG: mlo:mll6620 thiamine biosynthesis lipoprotein; ApbE family lipoprotein 418645 8324541 Amir_0382 Actinosynnema mirum DSM 43827 ApbE family lipoprotein YP_003098195.1 417932 D 446462 CDS YP_003098196.1 256374536 8324542 complement(418924..419154) 1 NC_013093.1 hypothetical protein 419154 8324542 Amir_0383 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098196.1 418924 R 446462 CDS YP_003098197.1 256374537 8324543 complement(419414..420451) 1 NC_013093.1 PFAM: ADP-ribosylation/Crystallin J1; KEGG: dol:Dole_0265 ADP-ribosylation/crystallin J1; ADP-ribosylation/Crystallin J1 420451 8324543 Amir_0384 Actinosynnema mirum DSM 43827 ADP-ribosylation/Crystallin J1 YP_003098197.1 419414 R 446462 CDS YP_003098198.1 256374538 8324544 420623..423445 1 NC_013093.1 PFAM: transcriptional activator domain; NB-ARC domain protein; transcriptional regulator domain protein; KEGG: scl:sce8759 hypothetical protein; SARP family transcriptional regulator 423445 8324544 Amir_0385 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003098198.1 420623 D 446462 CDS YP_003098199.1 256374539 8324545 complement(423636..424412) 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: bcb:BCB4264_A2458 hypothetical protein; G-D-S-L family lipolytic protein 424412 8324545 Amir_0386 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003098199.1 423636 R 446462 CDS YP_003098200.1 256374540 8324546 complement(424515..424955) 1 NC_013093.1 hypothetical protein 424955 8324546 Amir_0387 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098200.1 424515 R 446462 CDS YP_003098201.1 256374541 8324547 425108..425854 1 NC_013093.1 hypothetical protein 425854 8324547 Amir_0388 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098201.1 425108 D 446462 CDS YP_003098202.1 256374542 8324548 complement(425911..426903) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: sme:SM_b21003 oxidoreductase protein; luciferase-like monooxygenase 426903 8324548 Amir_0389 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003098202.1 425911 R 446462 CDS YP_003098203.1 256374543 8324549 427020..427901 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: acr:Acry_2830 LysR family transcriptional regulator; LysR family transcriptional regulator 427901 8324549 Amir_0390 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003098203.1 427020 D 446462 CDS YP_003098204.1 256374544 8324550 complement(428065..429006) 1 NC_013093.1 PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: slo:Shew_1116 ATPase, BadF/BadG/BcrA/BcrD type; BadF/BadG/BcrA/BcrD type ATPase 429006 8324550 Amir_0391 Actinosynnema mirum DSM 43827 BadF/BadG/BcrA/BcrD type ATPase YP_003098204.1 428065 R 446462 CDS YP_003098205.1 256374545 8324551 complement(429003..432230) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: glo:Glov_1721 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 432230 8324551 Amir_0392 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003098205.1 429003 R 446462 CDS YP_003098206.1 256374546 8324552 432351..433205 1 NC_013093.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rle:RL0016 FAA hydrolase family protein; 5-oxopent-3-ene-1,2, 5-tricarboxylatedecarboxylase 433205 8324552 Amir_0393 Actinosynnema mirum DSM 43827 5-oxopent-3-ene-1,2, 5-tricarboxylatedecarboxylase YP_003098206.1 432351 D 446462 CDS YP_003098207.1 256374547 8324553 433205..434617 1 NC_013093.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: xca:xccb100_4271 phosphopyruvate hydratase; mandelate racemase/muconate lactonizing protein 434617 8324553 Amir_0394 Actinosynnema mirum DSM 43827 mandelate racemase/muconate lactonizing protein YP_003098207.1 433205 D 446462 CDS YP_003098208.1 256374548 8324554 434593..435363 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bpe:BP1923 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 435363 8324554 Amir_0395 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003098208.1 434593 D 446462 CDS YP_003098209.1 256374549 8324555 435360..436289 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: xac:XAC4184 oxidoreductase; aldo/keto reductase 436289 8324555 Amir_0396 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003098209.1 435360 D 446462 CDS YP_003098210.1 256374550 8324556 436286..437110 1 NC_013093.1 PFAM: amidohydrolase 2; KEGG: mes:Meso_1610 amidohydrolase 2; amidohydrolase 2 437110 8324556 Amir_0397 Actinosynnema mirum DSM 43827 amidohydrolase 2 YP_003098210.1 436286 D 446462 CDS YP_003098211.1 256374551 8324557 437177..438277 1 NC_013093.1 PFAM: beta-lactamase; KEGG: bcz:pE33L466_0099 D-stereospecific peptide hydrolase; Serine-type D-Ala-D-Ala carboxypeptidase 438277 8324557 Amir_0398 Actinosynnema mirum DSM 43827 Serine-type D-Ala-D-Ala carboxypeptidase YP_003098211.1 437177 D 446462 CDS YP_003098212.1 256374552 8324558 complement(438344..439018) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: csa:Csal_0365 transcriptional regulator, GntR family; GntR family transcriptional regulator 439018 8324558 Amir_0399 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003098212.1 438344 R 446462 CDS YP_003098213.1 256374553 8324559 complement(439140..440183) 1 NC_013093.1 PFAM: sugar isomerase (SIS); KEGG: sus:Acid_1598 glutamine--fructose-6-phosphate transaminase (isomerizing); glutamine--fructose-6-phosphate transaminase 440183 8324559 Amir_0400 Actinosynnema mirum DSM 43827 glutamine--fructose-6-phosphate transaminase YP_003098213.1 439140 R 446462 CDS YP_003098214.1 256374554 8324560 complement(440530..441351) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_3555 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane proteint 441351 8324560 Amir_0401 Actinosynnema mirum DSM 43827 ABC transporter inner membrane proteint YP_003098214.1 440530 R 446462 CDS YP_003098215.1 256374555 8324561 complement(441348..442340) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bxe:Bxe_B0419 ABC sugar transporter, inner membrane subunit; sugar ABC transporter inner membrane protein 442340 8324561 Amir_0402 Actinosynnema mirum DSM 43827 sugar ABC transporter inner membrane protein YP_003098215.1 441348 R 446462 CDS YP_003098216.1 256374556 8324562 complement(442348..443628) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: mlo:mll4149 sugar ABC transporter, (sugar- binding protein); family 1 extracellular solute-binding protein 443628 8324562 Amir_0403 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003098216.1 442348 R 446462 CDS YP_003098217.1 256374557 8324563 443873..444622 1 NC_013093.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bcy:Bcer98_2752 GntR family transcriptional regulator; GntR family transcriptional regulator 444622 8324563 Amir_0404 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003098217.1 443873 D 446462 CDS YP_003098218.1 256374558 8324564 complement(444671..445618) 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aba:Acid345_2084 pyridoxal-5'-phosphate- dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit 445618 8324564 Amir_0405 Actinosynnema mirum DSM 43827 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003098218.1 444671 R 446462 CDS YP_003098219.1 256374559 8324565 complement(446394..447158) 1 NC_013093.1 PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: scl:sce0163 hypothetical protein; Extradiol ring-cleavage dioxygenase class III protein subunit B 447158 8324565 Amir_0406 Actinosynnema mirum DSM 43827 Extradiol ring-cleavage dioxygenase class III protein subunit B YP_003098219.1 446394 R 446462 CDS YP_003098220.1 256374560 8324566 complement(447158..447916) 1 NC_013093.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 447916 thiE 8324566 thiE Actinosynnema mirum DSM 43827 thiamine-phosphate pyrophosphorylase YP_003098220.1 447158 R 446462 CDS YP_003098221.1 256374561 8324567 448503..449510 1 NC_013093.1 TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: azc:AZC_3554 glycine oxidase precursor; glycine oxidase ThiO 449510 8324567 Amir_0408 Actinosynnema mirum DSM 43827 glycine oxidase ThiO YP_003098221.1 448503 D 446462 CDS YP_003098222.1 256374562 8324568 449507..449704 1 NC_013093.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mms:mma_0316 thiamine biosynthesis protein ThiS; thiamine biosynthesis protein ThiS 449704 8324568 Amir_0409 Actinosynnema mirum DSM 43827 thiamine biosynthesis protein ThiS YP_003098222.1 449507 D 446462 CDS YP_003098223.1 256374563 8324569 449707..450495 1 NC_013093.1 PFAM: thiazole biosynthesis family protein; KEGG: rce:RC1_3100 thiazole biosynthesis protein ThiG; thiazole biosynthesis family protein 450495 8324569 Amir_0410 Actinosynnema mirum DSM 43827 thiazole biosynthesis family protein YP_003098223.1 449707 D 446462 CDS YP_003098224.1 256374564 8324570 450580..450999 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bcm:Bcenmc03_5734 MarR family transcriptional regulator; MarR family transcriptional regulator 450999 8324570 Amir_0411 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003098224.1 450580 D 446462 CDS YP_003098225.1 256374565 8324571 complement(451015..451833) 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: mlo:mll3178 hypothetical protein; O-methyltransferase 451833 8324571 Amir_0412 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003098225.1 451015 R 446462 CDS YP_003098226.1 256374566 8324572 complement(451917..452123) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 452123 8324572 Amir_0413 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098226.1 451917 R 446462 CDS YP_003098227.1 256374567 8324573 complement(452143..452997) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 452997 8324573 Amir_0414 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003098227.1 452143 R 446462 CDS YP_003098228.1 256374568 8324574 453216..453383 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 453383 8324574 Amir_0415 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098228.1 453216 D 446462 CDS YP_003098229.1 256374569 8324575 453387..453620 1 NC_013093.1 hypothetical protein 453620 8324575 Amir_0416 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098229.1 453387 D 446462 CDS YP_003098230.1 256374570 8324576 453617..453964 1 NC_013093.1 hypothetical protein 453964 8324576 Amir_0417 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098230.1 453617 D 446462 CDS YP_003098231.1 256374571 8324577 complement(453918..454655) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bph:Bphy_4607 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 454655 8324577 Amir_0418 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003098231.1 453918 R 446462 CDS YP_003098232.1 256374572 8324578 454677..455330 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bxe:Bxe_B1146 TetR family transcriptional regulator; TetR family transcriptional regulator 455330 8324578 Amir_0419 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098232.1 454677 D 446462 CDS YP_003098233.1 256374573 8324579 complement(455336..456040) 1 NC_013093.1 KEGG: rec:RHECIAT_CH0002869 hydrolase protein; hydrolase protein 456040 8324579 Amir_0420 Actinosynnema mirum DSM 43827 hydrolase protein YP_003098233.1 455336 R 446462 CDS YP_003098234.1 256374574 8324580 456177..456746 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: smd:Smed_4442 transcriptional regulator, TetR family; TetR family transcriptional regulator 456746 8324580 Amir_0421 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098234.1 456177 D 446462 CDS YP_003098235.1 256374575 8324581 complement(456953..457957) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: cak:Caul_0434 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 457957 8324581 Amir_0422 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003098235.1 456953 R 446462 CDS YP_003098236.1 256374576 8324582 458084..458638 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: cak:Caul_0435 TetR family transcriptional regulator; TetR family transcriptional regulator 458638 8324582 Amir_0423 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098236.1 458084 D 446462 CDS YP_003098237.1 256374577 8324583 complement(458684..459514) 1 NC_013093.1 TIGRFAM: phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase type-1; KEGG: sfu:Sfum_1692 phosphomethylpyrimidine kinase; phosphomethylpyrimidine kinase 459514 8324583 Amir_0424 Actinosynnema mirum DSM 43827 phosphomethylpyrimidine kinase YP_003098237.1 458684 R 446462 CDS YP_003098238.1 256374578 8324584 complement(459516..461159) 1 NC_013093.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 461159 8324584 Amir_0425 Actinosynnema mirum DSM 43827 thiamine biosynthesis protein ThiC YP_003098238.1 459516 R 446462 CDS YP_003098239.1 256374579 8324585 461485..462102 1 NC_013093.1 hypothetical protein 462102 8324585 Amir_0426 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098239.1 461485 D 446462 CDS YP_003098240.1 256374580 8324586 complement(462297..462884) 1 NC_013093.1 KEGG: pmr:PMI2825 peptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase; peptide deformylase 462884 8324586 Amir_0427 Actinosynnema mirum DSM 43827 peptide deformylase YP_003098240.1 462297 R 446462 CDS YP_003098241.1 256374581 8324587 463048..463332 1 NC_013093.1 hypothetical protein 463332 8324587 Amir_0428 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098241.1 463048 D 446462 CDS YP_003098242.1 256374582 8324588 463329..463991 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 463991 8324588 Amir_0429 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098242.1 463329 D 446462 CDS YP_003098243.1 256374583 8324589 complement(464055..464762) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: mes:Meso_0568 transcriptional regulator, GntR family; GntR family transcriptional regulator 464762 8324589 Amir_0430 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003098243.1 464055 R 446462 CDS YP_003098244.1 256374584 8324590 464849..465946 1 NC_013093.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: gme:Gmet_2577 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 465946 8324590 Amir_0431 Actinosynnema mirum DSM 43827 NADH:flavin oxidoreductase/NADH oxidase YP_003098244.1 464849 D 446462 CDS YP_003098245.1 256374585 8324591 466404..468608 1 NC_013093.1 KEGG: mrd:Mrad2831_5798 AAA family ATPase, CDC48 subfamily protein; PFAM: ATPase AAA; SMART: ATPase AAA; Microtubule-severing ATPase 468608 8324591 Amir_0432 Actinosynnema mirum DSM 43827 Microtubule-severing ATPase YP_003098245.1 466404 D 446462 CDS YP_003098246.1 256374586 8324592 468892..469416 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: scl:sce7901 ECF family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 469416 8324592 Amir_0433 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003098246.1 468892 D 446462 CDS YP_003098247.1 256374587 8324593 469413..470174 1 NC_013093.1 KEGG: mxa:MXAN_3349 DnaJ domain protein; DnaJ domain-containing protein 470174 8324593 Amir_0434 Actinosynnema mirum DSM 43827 DnaJ domain-containing protein YP_003098247.1 469413 D 446462 CDS YP_003098248.1 256374588 8324594 complement(470346..471323) 1 NC_013093.1 KEGG: mag:amb0603 phosphatidylserine synthase; TIGRFAM: CDP-diacylglycerol/serine O- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; CDP-diacylglycerol/serineO- phosphatidyltransferase 471323 8324594 Amir_0435 Actinosynnema mirum DSM 43827 CDP-diacylglycerol/serineO- phosphatidyltransferase YP_003098248.1 470346 R 446462 CDS YP_003098249.1 256374589 8324595 complement(471327..472040) 1 NC_013093.1 KEGG: rce:RC1_1432 phosphatidylserine decarboxylase- like protein, TIGRFAM: phosphatidylserine decarboxylase related protein; PFAM: phosphatidylserine decarboxylase-related; phosphatidylserine decarboxylase-like protein 472040 8324595 Amir_0436 Actinosynnema mirum DSM 43827 phosphatidylserine decarboxylase-like protein YP_003098249.1 471327 R 446462 CDS YP_003098250.1 256374590 8324596 complement(472257..473768) 1 NC_013093.1 PFAM: peptidase M48 Ste24p; KEGG: sfu:Sfum_1032 peptidase M48, Ste24p; peptidase M48 Ste24p 473768 8324596 Amir_0437 Actinosynnema mirum DSM 43827 peptidase M48 Ste24p YP_003098250.1 472257 R 446462 CDS YP_003098251.1 256374591 8324597 complement(473915..475120) 1 NC_013093.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: afw:Anae109_1445 molybdenum cofactor synthesis domain-containing protein; molybdenum cofactor synthesis domain-containing protein 475120 8324597 Amir_0438 Actinosynnema mirum DSM 43827 molybdenum cofactor synthesis domain-containing protein YP_003098251.1 473915 R 446462 CDS YP_003098252.1 256374592 8324598 475190..475798 1 NC_013093.1 PFAM: protein of unknown function DUF124; KEGG: hypothetical protein; hypothetical protein 475798 8324598 Amir_0439 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098252.1 475190 D 446462 CDS YP_003098253.1 256374593 8324599 475930..476136 1 NC_013093.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ank:AnaeK_2630 cold-shock DNA-binding domain protein; cold-shock DNA-binding domain-containing protein 476136 8324599 Amir_0440 Actinosynnema mirum DSM 43827 cold-shock DNA-binding domain-containing protein YP_003098253.1 475930 D 446462 CDS YP_003098254.1 256374594 8324600 476271..477605 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; protein of unknown function RIO1; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: ade:Adeh_1074 serine/threonine protein kinase; serine/threonine protein kinase 477605 8324600 Amir_0441 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003098254.1 476271 D 446462 CDS YP_003098255.1 256374595 8324601 477845..479467 1 NC_013093.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: bcb:BCB4264_A0298 chaperonin GroL; chaperonin GroEL 479467 8324601 Amir_0442 Actinosynnema mirum DSM 43827 chaperonin GroEL YP_003098255.1 477845 D 446462 CDS YP_003098256.1 256374596 8324602 complement(479947..480444) 1 NC_013093.1 hypothetical protein 480444 8324602 Amir_0443 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098256.1 479947 R 446462 CDS YP_003098257.1 256374597 8324603 complement(480441..481046) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: sus:Acid_3132 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 481046 8324603 Amir_0444 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003098257.1 480441 R 446462 CDS YP_003098258.1 256374598 8324604 481427..482101 1 NC_013093.1 PFAM: CutC family protein; KEGG: bcj:BCAL0655 CutC family protein; CutC family protein 482101 8324604 Amir_0445 Actinosynnema mirum DSM 43827 CutC family protein YP_003098258.1 481427 D 446462 CDS YP_003098259.1 256374599 8324605 482648..483922 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: rle:pRL100263 substrate-binding component of ABC transporter; family 1 extracellular solute-binding protein 483922 8324605 Amir_0446 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003098259.1 482648 D 446462 CDS YP_003098260.1 256374600 8324606 483919..484830 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mxa:MXAN_7294 sugar ABC transporter, permease protein; sugar ABC transporter permease 484830 8324606 Amir_0447 Actinosynnema mirum DSM 43827 sugar ABC transporter permease YP_003098260.1 483919 D 446462 CDS YP_003098261.1 256374601 8324607 484827..485660 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlt:Rleg2_3667 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 485660 8324607 Amir_0448 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098261.1 484827 D 446462 CDS YP_003098262.1 256374602 8324608 485657..487000 1 NC_013093.1 PFAM: glycoside hydrolase, family 20, catalytic core; KEGG: nar:Saro_2417 beta-N-acetylhexosaminidase; beta-N-acetylhexosaminidase 487000 8324608 Amir_0449 Actinosynnema mirum DSM 43827 beta-N-acetylhexosaminidase YP_003098262.1 485657 D 446462 CDS YP_003098263.1 256374603 8324609 complement(487001..487255) 1 NC_013093.1 PFAM: PspC domain protein; KEGG: cbc:CbuK_0644 stress-responsive transcriptional regulator; phage shock protein PspC 487255 8324609 Amir_0450 Actinosynnema mirum DSM 43827 phage shock protein PspC YP_003098263.1 487001 R 446462 CDS YP_003098264.1 256374604 8324610 487494..488600 1 NC_013093.1 PFAM: protein of unknown function DUF182; KEGG: msl:Msil_0236 protein of unknown function DUF182; hypothetical protein 488600 8324610 Amir_0451 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098264.1 487494 D 446462 CDS YP_003098265.1 256374605 8324611 489427..490365 1 NC_013093.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 490365 8324611 Amir_0452 Actinosynnema mirum DSM 43827 O-succinylbenzoate synthase YP_003098265.1 489427 D 446462 CDS YP_003098266.1 256374606 8324612 complement(490565..492217) 1 NC_013093.1 PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: SSL2; DNA helicase; K10843 DNA excision repair protein ERCC-3; type III restriction protein res subunit 492217 8324612 Amir_0453 Actinosynnema mirum DSM 43827 type III restriction protein res subunit YP_003098266.1 490565 R 446462 CDS YP_003098267.1 256374607 8324613 492343..492873 1 NC_013093.1 hypothetical protein 492873 8324613 Amir_0454 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098267.1 492343 D 446462 CDS YP_003098268.1 256374608 8324614 492929..493387 1 NC_013093.1 hypothetical protein 493387 8324614 Amir_0455 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098268.1 492929 D 446462 CDS YP_003098269.1 256374609 8324615 493478..494566 1 NC_013093.1 KEGG: Prp2; proline rich protein 2; hypothetical protein 494566 8324615 Amir_0456 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098269.1 493478 D 446462 CDS YP_003098270.1 256374610 8324616 complement(494631..495632) 1 NC_013093.1 KEGG: twin-arginine translocation pathway signal; K02051 sulfonate/nitrate/taurine transport system substrate-binding protein; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein 495632 8324616 Amir_0457 Actinosynnema mirum DSM 43827 nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein YP_003098270.1 494631 R 446462 CDS YP_003098271.1 256374611 8324617 496042..499320 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; nitrate and nitrite sensing domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: mag:amb3383 methyl-accepting chemotaxis protein; sensor with HAMP domain 499320 8324617 Amir_0458 Actinosynnema mirum DSM 43827 sensor with HAMP domain YP_003098271.1 496042 D 446462 CDS YP_003098272.1 256374612 8324618 499317..499736 1 NC_013093.1 PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_2813 roadblock/LC7 family protein; Roadblock/LC7 family protein 499736 8324618 Amir_0459 Actinosynnema mirum DSM 43827 Roadblock/LC7 family protein YP_003098272.1 499317 D 446462 CDS YP_003098273.1 256374613 8324619 499962..500510 1 NC_013093.1 PFAM: protein of unknown function DUF742; hypothetical protein 500510 8324619 Amir_0460 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098273.1 499962 D 446462 CDS YP_003098274.1 256374614 8324620 500491..501099 1 NC_013093.1 PFAM: protein of unknown function ATP binding; KEGG: nmn:NMCC_1665 hypothetical protein; hypothetical protein 501099 8324620 Amir_0461 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098274.1 500491 D 446462 CDS YP_003098275.1 256374615 8324621 complement(501188..502924) 1 NC_013093.1 KEGG: dac:Daci_2082 hypothetical protein; hypothetical protein 502924 8324621 Amir_0462 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098275.1 501188 R 446462 CDS YP_003098276.1 256374616 8324622 complement(503041..505284) 1 NC_013093.1 KEGG: acp:A2cp1_2891 response regulator receiver; hypothetical protein 505284 8324622 Amir_0463 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098276.1 503041 R 446462 CDS YP_003098277.1 256374617 8324623 505350..505535 1 NC_013093.1 hypothetical protein 505535 8324623 Amir_0464 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098277.1 505350 D 446462 CDS YP_003098278.1 256374618 8324624 505641..507044 1 NC_013093.1 PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: sat:SYN_00517 NAD-dependent malic enzyme; malate dehydrogenase 507044 8324624 Amir_0465 Actinosynnema mirum DSM 43827 malate dehydrogenase YP_003098278.1 505641 D 446462 CDS YP_003098279.1 256374619 8324625 507285..507758 1 NC_013093.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: eli:ELI_06520 molybdopterin cofactor biosynthesis MoaC region; molybdenum cofactor biosynthesis protein C 507758 8324625 Amir_0466 Actinosynnema mirum DSM 43827 molybdenum cofactor biosynthesis protein C YP_003098279.1 507285 D 446462 CDS YP_003098280.1 256374620 8324626 507755..508237 1 NC_013093.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: sfu:Sfum_0070 molybdenum cofactor synthesis domain; molybdenum cofactor synthesis domain-containing protein 508237 8324626 Amir_0467 Actinosynnema mirum DSM 43827 molybdenum cofactor synthesis domain-containing protein YP_003098280.1 507755 D 446462 CDS YP_003098281.1 256374621 8324627 508234..508659 1 NC_013093.1 PFAM: molybdopterin biosynthesis MoaE protein; KEGG: scl:sce2941 molybdopterin-converting factor chain 2; molybdopterin biosynthesis MoaE protein 508659 8324627 Amir_0468 Actinosynnema mirum DSM 43827 molybdopterin biosynthesis MoaE protein YP_003098281.1 508234 D 446462 CDS YP_003098282.1 256374622 8324628 complement(509101..509775) 1 NC_013093.1 PFAM: transglycosylase domain protein; SMART: peptidoglycan-binding LysM; KEGG: vei:Veis_4083 peptidoglycan-binding LysM; transglycosylase domain-containing protein 509775 8324628 Amir_0469 Actinosynnema mirum DSM 43827 transglycosylase domain-containing protein YP_003098282.1 509101 R 446462 CDS YP_003098283.1 256374623 8324629 complement(510138..510401) 1 NC_013093.1 PFAM: thiamineS protein; KEGG: ade:Adeh_1120 molybdopterin synthase subunit MoaE / molybdopterin synthase subunit MoaD; sulfur carrier protein ThiS 510401 8324629 Amir_0470 Actinosynnema mirum DSM 43827 sulfur carrier protein ThiS YP_003098283.1 510138 R 446462 CDS YP_003098284.1 256374624 8324630 complement(510403..511428) 1 NC_013093.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 511428 moaA 8324630 moaA Actinosynnema mirum DSM 43827 molybdenum cofactor biosynthesis protein A YP_003098284.1 510403 R 446462 CDS YP_003098285.1 256374625 8324631 511563..512024 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bja:bll4976 transcriptional regulatory protein; MarR family transcriptional regulator 512024 8324631 Amir_0472 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003098285.1 511563 D 446462 CDS YP_003098286.1 256374626 8324632 512044..512832 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: csa:Csal_0794 HAD-superfamily hydrolase, subfamily IIA; HAD superfamily hydrolase 512832 8324632 Amir_0473 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003098286.1 512044 D 446462 CDS YP_003098287.1 256374627 8324633 512991..513695 1 NC_013093.1 PFAM: protein of unknown function DUF1503; KEGG: scl:sce8705 hypothetical protein; hypothetical protein 513695 8324633 Amir_0474 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098287.1 512991 D 446462 CDS YP_003098288.1 256374628 8324634 514093..514917 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: serine/threonine protein phosphatase; metallophosphoesterase 514917 8324634 Amir_0475 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003098288.1 514093 D 446462 CDS YP_003098289.1 256374629 8324635 complement(514951..515325) 1 NC_013093.1 PFAM: protein of unknown function DUF307; KEGG: rpa:RPA0774 hypothetical protein; hypothetical protein 515325 8324635 Amir_0476 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098289.1 514951 R 446462 CDS YP_003098290.1 256374630 8324636 515358..516356 1 NC_013093.1 PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; oxidoreductase domain; KEGG: similar to dimeric dihydrodiol dehydrogenase; oxidoreductase domain-containing protein 516356 8324636 Amir_0477 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003098290.1 515358 D 446462 CDS YP_003098291.1 256374631 8324637 complement(516334..517299) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bbt:BBta_0237 OmpA family protein; TetR family transcriptional regulator 517299 8324637 Amir_0478 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098291.1 516334 R 446462 CDS YP_003098292.1 256374632 8324638 517475..518131 1 NC_013093.1 PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: afw:Anae109_2037 HAD family hydrolase; Haloacid dehalogenase domain-containing protein hydrolase 518131 8324638 Amir_0479 Actinosynnema mirum DSM 43827 Haloacid dehalogenase domain-containing protein hydrolase YP_003098292.1 517475 D 446462 CDS YP_003098293.1 256374633 8324639 complement(518202..518405) 1 NC_013093.1 hypothetical protein 518405 8324639 Amir_0480 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098293.1 518202 R 446462 CDS YP_003098294.1 256374634 8324640 518534..518929 1 NC_013093.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: bcy:Bcer98_3497 cold-shock DNA-binding domain- containing protein; cold-shock DNA-binding domain-containing protein 518929 8324640 Amir_0481 Actinosynnema mirum DSM 43827 cold-shock DNA-binding domain-containing protein YP_003098294.1 518534 D 446462 CDS YP_003098295.1 256374635 8324641 complement(519009..519494) 1 NC_013093.1 hypothetical protein 519494 8324641 Amir_0482 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098295.1 519009 R 446462 CDS YP_003098296.1 256374636 8324642 complement(519518..521248) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_4876 major facilitator transporter; major facilitator superfamily protein 521248 8324642 Amir_0483 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098296.1 519518 R 446462 CDS YP_003098297.1 256374637 8324643 complement(521305..522084) 1 NC_013093.1 PFAM: glutamine cyclotransferase; KEGG: sus:Acid_3566 glutamine cyclotransferase; glutamine cyclotransferase 522084 8324643 Amir_0484 Actinosynnema mirum DSM 43827 glutamine cyclotransferase YP_003098297.1 521305 R 446462 CDS YP_003098298.1 256374638 8324644 522145..523071 1 NC_013093.1 KEGG: GL17023 gene product from transcript GL17023- RA; hypothetical protein 523071 8324644 Amir_0485 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098298.1 522145 D 446462 CDS YP_003098299.1 256374639 8324645 523068..525896 1 NC_013093.1 KEGG: nha:Nham_3709 hypothetical protein; hypothetical protein 525896 8324645 Amir_0486 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098299.1 523068 D 446462 CDS YP_003098300.1 256374640 8324646 complement(526006..526251) 1 NC_013093.1 hypothetical protein 526251 8324646 Amir_0487 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098300.1 526006 R 446462 CDS YP_003098301.1 256374641 8324647 526391..527830 1 NC_013093.1 PFAM: xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: acp:A2cp1_3490 xanthine/uracil/vitamin C permease; xanthine/uracil/vitamin C permease 527830 8324647 Amir_0488 Actinosynnema mirum DSM 43827 xanthine/uracil/vitamin C permease YP_003098301.1 526391 D 446462 CDS YP_003098302.1 256374642 8324648 527995..528441 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bvi:Bcep1808_5100 MarR family transcriptional regulator; MarR family transcriptional regulator 528441 8324648 Amir_0489 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003098302.1 527995 D 446462 CDS YP_003098303.1 256374643 8324649 528446..529831 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: bpy:Bphyt_5813 major facilitator superfamily MFS_1; major facilitator superfamily protein 529831 8324649 Amir_0490 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098303.1 528446 D 446462 CDS YP_003098304.1 256374644 8324650 529828..531102 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: gdi:GDI0684 major facilitator transporter; major facilitator superfamily protein 531102 8324650 Amir_0491 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098304.1 529828 D 446462 CDS YP_003098305.1 256374645 8324651 complement(531287..531916) 1 NC_013093.1 PFAM: manganese and iron superoxide dismutase; KEGG: hypothetical protein; superoxide dismutase 531916 8324651 Amir_0492 Actinosynnema mirum DSM 43827 superoxide dismutase YP_003098305.1 531287 R 446462 CDS YP_003098306.1 256374646 8324652 532020..533633 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6528 ABC transporter, ATP-binding protein; ABC transporter 533633 8324652 Amir_0493 Actinosynnema mirum DSM 43827 ABC transporter YP_003098306.1 532020 D 446462 CDS YP_003098307.1 256374647 8324653 533638..534048 1 NC_013093.1 hypothetical protein 534048 8324653 Amir_0494 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098307.1 533638 D 446462 CDS YP_003098308.1 256374648 8324654 complement(534080..535573) 1 NC_013093.1 PFAM: glutamate--cysteine ligase GCS2; KEGG: scl:sce0051 hypothetical protein; glutamate--cysteine ligase GCS2 535573 8324654 Amir_0495 Actinosynnema mirum DSM 43827 glutamate--cysteine ligase GCS2 YP_003098308.1 534080 R 446462 CDS YP_003098309.1 256374649 8324655 535700..536551 1 NC_013093.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mes:Meso_2208 tRNA/rRNA methyltransferase (SpoU); tRNA/rRNA methyltransferase SpoU 536551 8324655 Amir_0496 Actinosynnema mirum DSM 43827 tRNA/rRNA methyltransferase SpoU YP_003098309.1 535700 D 446462 CDS YP_003098310.1 256374650 8324656 536593..537243 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 537243 8324656 Amir_0497 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098310.1 536593 D 446462 CDS YP_003098311.1 256374651 8324657 537256..538983 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; dienelactone hydrolase; phospholipase/carboxylesterase; KEGG: hypothetical protein; peptidase S9 prolyl oligopeptidase active site domain-containing protein 538983 8324657 Amir_0498 Actinosynnema mirum DSM 43827 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_003098311.1 537256 D 446462 CDS YP_003098312.1 256374652 8324658 complement(539369..540679) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: lpp:lpp1608 hypothetical protein; major facilitator superfamily protein 540679 8324658 Amir_0499 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098312.1 539369 R 446462 CDS YP_003098313.1 256374653 8324659 540751..542352 1 NC_013093.1 PFAM: polysaccharide lyase family 8; polysaccharide lyase 8 alpha-helical; KEGG: vvy:VVA1636 hypothetical protein; polysaccharide lyase family 8 542352 8324659 Amir_0500 Actinosynnema mirum DSM 43827 polysaccharide lyase family 8 YP_003098313.1 540751 D 446462 CDS YP_003098314.1 256374654 8324660 complement(542596..543255) 1 NC_013093.1 KEGG: rpi:Rpic_0717 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase 543255 8324660 Amir_0501 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase YP_003098314.1 542596 R 446462 CDS YP_003098315.1 256374655 8324661 complement(543312..544157) 1 NC_013093.1 KEGG: scl:sce6547 urease accessory protein UreD; urease accessory protein UreD 544157 8324661 Amir_0502 Actinosynnema mirum DSM 43827 urease accessory protein UreD YP_003098315.1 543312 R 446462 CDS YP_003098316.1 256374656 8324662 544235..544771 1 NC_013093.1 hypothetical protein 544771 8324662 Amir_0503 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098316.1 544235 D 446462 CDS YP_003098317.1 256374657 8324663 complement(544741..545454) 1 NC_013093.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: scl:sce6551 urease accessory protein G; urease accessory protein UreG 545454 8324663 Amir_0504 Actinosynnema mirum DSM 43827 urease accessory protein UreG YP_003098317.1 544741 R 446462 CDS YP_003098318.1 256374658 8324664 complement(545444..546106) 1 NC_013093.1 KEGG: ank:AnaeK_0974 hypothetical protein; hypothetical protein 546106 8324664 Amir_0505 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098318.1 545444 R 446462 CDS YP_003098319.1 256374659 8324665 complement(546215..547912) 1 NC_013093.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 547912 ureC 8324665 ureC Actinosynnema mirum DSM 43827 urease subunit alpha YP_003098319.1 546215 R 446462 CDS YP_003098320.1 256374660 8324666 complement(547909..548220) 1 NC_013093.1 KEGG: atu:Atu2405 urease subunit beta; TIGRFAM: urease subunit beta; PFAM: Urease beta subunit; urease subunit beta 548220 8324666 Amir_0507 Actinosynnema mirum DSM 43827 urease subunit beta YP_003098320.1 547909 R 446462 CDS YP_003098321.1 256374661 8324667 complement(548279..548581) 1 NC_013093.1 KEGG: oan:Oant_0332 urease subunit gamma; TIGRFAM: urease subunit gamma; PFAM: Urease gamma subunit region; urease subunit gamma 548581 8324667 Amir_0508 Actinosynnema mirum DSM 43827 urease subunit gamma YP_003098321.1 548279 R 446462 CDS YP_003098322.1 256374662 8324668 548814..549929 1 NC_013093.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; citrate synthase 2 549929 8324668 Amir_0509 Actinosynnema mirum DSM 43827 citrate synthase 2 YP_003098322.1 548814 D 446462 CDS YP_003098323.1 256374663 8324669 550082..550912 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sus:Acid_0079 ABC transporter; ABC transporter 550912 8324669 Amir_0510 Actinosynnema mirum DSM 43827 ABC transporter YP_003098323.1 550082 D 446462 CDS YP_003098324.1 256374664 8324670 550909..551709 1 NC_013093.1 PFAM: ABC transporter; KEGG: mxa:MXAN_1598 ABC transporter, permease protein, ABC-2 family; ABC transporter 551709 8324670 Amir_0511 Actinosynnema mirum DSM 43827 ABC transporter YP_003098324.1 550909 D 446462 CDS YP_003098325.1 256374665 8324671 551682..552701 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sus:Acid_1273 integral membrane sensor signal transduction histidine kinase; histidine kinase 552701 8324671 Amir_0512 Actinosynnema mirum DSM 43827 histidine kinase YP_003098325.1 551682 D 446462 CDS YP_003098326.1 256374666 8324672 552766..553395 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: sus:Acid_2683 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 553395 8324672 Amir_0513 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003098326.1 552766 D 446462 CDS YP_003098327.1 256374667 8324673 553647..554780 1 NC_013093.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 554780 8324673 Amir_0514 Actinosynnema mirum DSM 43827 phosphoserine aminotransferase YP_003098327.1 553647 D 446462 CDS YP_003098328.1 256374668 8324674 555000..555815 1 NC_013093.1 hypothetical protein 555815 8324674 Amir_0515 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098328.1 555000 D 446462 CDS YP_003098329.1 256374669 8324675 556396..556770 1 NC_013093.1 hypothetical protein 556770 8324675 Amir_0516 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098329.1 556396 D 446462 CDS YP_003098330.1 256374670 8324676 556763..557443 1 NC_013093.1 KEGG: similar to hedgehog protein; hypothetical protein 557443 8324676 Amir_0517 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098330.1 556763 D 446462 CDS YP_003098331.1 256374671 8324677 complement(557503..557742) 1 NC_013093.1 hypothetical protein 557742 8324677 Amir_0518 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098331.1 557503 R 446462 CDS YP_003098332.1 256374672 8324678 557855..559624 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rce:RC1_1837 ABC transporter, ATP-binding; ABC transporter 559624 8324678 Amir_0519 Actinosynnema mirum DSM 43827 ABC transporter YP_003098332.1 557855 D 446462 CDS YP_003098333.1 256374673 8324679 559621..561579 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: bha:BH1126 ABC transporter ATP-binding protein; ABC transporter 561579 8324679 Amir_0520 Actinosynnema mirum DSM 43827 ABC transporter YP_003098333.1 559621 D 446462 CDS YP_003098334.1 256374674 8324680 562328..562894 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: gdj:Gdia_1592 regulatory protein TetR; TetR family transcriptional regulator 562894 8324680 Amir_0521 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098334.1 562328 D 446462 CDS YP_003098335.1 256374675 8324681 563263..564681 1 NC_013093.1 PFAM: amino acid permease-associated region; KEGG: bpt:Bpet1644 amino acid transporter; amino acid permease-associated protein 564681 8324681 Amir_0522 Actinosynnema mirum DSM 43827 amino acid permease-associated protein YP_003098335.1 563263 D 446462 CDS YP_003098336.1 256374676 8324682 564778..565650 1 NC_013093.1 PFAM: Aldose 1-epimerase; KEGG: sfv:SFV_3620 aldose-1-epimerase; Aldose 1-epimerase 565650 8324682 Amir_0523 Actinosynnema mirum DSM 43827 Aldose 1-epimerase YP_003098336.1 564778 D 446462 CDS YP_003098337.1 256374677 8324683 565670..566863 1 NC_013093.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: bha:BH3008 hypothetical protein; amidohydrolase 566863 8324683 Amir_0524 Actinosynnema mirum DSM 43827 amidohydrolase YP_003098337.1 565670 D 446462 CDS YP_003098338.1 256374678 8324684 complement(566946..568091) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bat:BAS5190 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 568091 8324684 Amir_0525 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003098338.1 566946 R 446462 CDS YP_003098339.1 256374679 8324685 568174..568770 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rme:Rmet_3794 transcriptional regulator, TetR family; TetR family transcriptional regulator 568770 8324685 Amir_0526 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098339.1 568174 D 446462 CDS YP_003098340.1 256374680 8324686 568767..569705 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: sit:TM1040_3042 PfkB; PfkB domain-containing protein 569705 8324686 Amir_0527 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003098340.1 568767 D 446462 CDS YP_003098341.1 256374681 8324687 569976..571289 1 NC_013093.1 KEGG: scl:sce8281 hypothetical protein; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; citrate synthase I 571289 8324687 Amir_0528 Actinosynnema mirum DSM 43827 citrate synthase I YP_003098341.1 569976 D 446462 CDS YP_003098342.1 256374682 8324688 571555..572820 1 NC_013093.1 PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: cvi:CV_3481 deoxyribodipyrimidine photo-lyase; deoxyribodipyrimidine photo-lyase 572820 8324688 Amir_0529 Actinosynnema mirum DSM 43827 deoxyribodipyrimidine photo-lyase YP_003098342.1 571555 D 446462 CDS YP_003098343.1 256374683 8324689 complement(572906..573550) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: tgr:Tgr7_2171 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator 573550 8324689 Amir_0530 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003098343.1 572906 R 446462 CDS YP_003098344.1 256374684 8324690 complement(573565..574854) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: mmr:Mmar10_2544 signal transduction histidine kinase; histidine kinase 574854 8324690 Amir_0531 Actinosynnema mirum DSM 43827 histidine kinase YP_003098344.1 573565 R 446462 CDS YP_003098345.1 256374685 8324691 complement(575005..576246) 1 NC_013093.1 KEGG: scl:sce9075 hypothetical protein; sodium ABC transporter permease 576246 8324691 Amir_0532 Actinosynnema mirum DSM 43827 sodium ABC transporter permease YP_003098345.1 575005 R 446462 CDS YP_003098346.1 256374686 8324692 complement(576243..577196) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH1166 ABC transporter ATP-binding protein; ABC transporter 577196 8324692 Amir_0533 Actinosynnema mirum DSM 43827 ABC transporter YP_003098346.1 576243 R 446462 CDS YP_003098347.1 256374687 8324693 complement(577222..577482) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: gdi:GDI1973 HTH-type transcriptional regulator; XRE family transcriptional regulator 577482 8324693 Amir_0534 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003098347.1 577222 R 446462 CDS YP_003098348.1 256374688 8324694 577666..578109 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: lpn:lpg2755 hypothetical protein; hypothetical protein 578109 8324694 Amir_0535 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098348.1 577666 D 446462 CDS YP_003098349.1 256374689 8324695 578130..578438 1 NC_013093.1 hypothetical protein 578438 8324695 Amir_0536 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098349.1 578130 D 446462 CDS YP_003098350.1 256374690 8324696 578435..580219 1 NC_013093.1 KEGG: predicted gene, 100041170; hypothetical protein 580219 8324696 Amir_0537 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098350.1 578435 D 446462 CDS YP_003098351.1 256374691 8324697 580973..582172 1 NC_013093.1 PFAM: Amidohydrolase 3; KEGG: bac:BamMC406_5450 N-isopropylammelide isopropylaminohydrolase; N-isopropylammelide isopropylaminohydrolase 582172 8324697 Amir_0538 Actinosynnema mirum DSM 43827 N-isopropylammelide isopropylaminohydrolase YP_003098351.1 580973 D 446462 CDS YP_003098352.1 256374692 8324698 complement(582162..583166) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pzu:PHZ_c1983 alcohol dehydrogenase, zinc- containing; alcohol dehydrogenase zinc-binding domain-containing protein 583166 8324698 Amir_0539 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003098352.1 582162 R 446462 CDS YP_003098353.1 256374693 8324699 complement(583222..583977) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bur:Bcep18194_A4874 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 583977 8324699 Amir_0540 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003098353.1 583222 R 446462 CDS YP_003098354.1 256374694 8324700 complement(584070..584606) 1 NC_013093.1 KEGG: tgr:Tgr7_2517 hypothetical protein; hypothetical protein 584606 8324700 Amir_0541 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098354.1 584070 R 446462 CDS YP_003098355.1 256374695 8324701 complement(584603..587401) 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: bpt:Bpet4245 hypothetical protein; cell division protein FtsK/SpoIIIE 587401 8324701 Amir_0542 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003098355.1 584603 R 446462 CDS YP_003098356.1 256374696 8324702 complement(587403..587654) 1 NC_013093.1 hypothetical protein 587654 8324702 Amir_0543 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098356.1 587403 R 446462 CDS YP_003098357.1 256374697 8324703 complement(587651..587911) 1 NC_013093.1 hypothetical protein 587911 8324703 Amir_0544 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098357.1 587651 R 446462 CDS YP_003098358.1 256374698 8324704 complement(588061..589773) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 589773 8324704 Amir_0545 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098358.1 588061 R 446462 CDS YP_003098359.1 256374699 8324705 590316..590795 1 NC_013093.1 hypothetical protein 590795 8324705 Amir_0546 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098359.1 590316 D 446462 CDS YP_003098360.1 256374700 8324706 complement(590868..591659) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: spe:Spro_0615 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 591659 8324706 Amir_0547 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003098360.1 590868 R 446462 CDS YP_003098361.1 256374701 8324707 complement(591709..592527) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: dvm:DvMF_0511 transcriptional regulator, LysR family; LysR family transcriptional regulator 592527 8324707 Amir_0548 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003098361.1 591709 R 446462 CDS YP_003098362.1 256374702 8324708 592602..593429 1 NC_013093.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: phenazine biosynthesis PhzC/PhzF protein; KEGG: aha:AHA_2368 phenazine biosynthesis protein PhzF; phenazine biosynthesis protein PhzF family 593429 8324708 Amir_0549 Actinosynnema mirum DSM 43827 phenazine biosynthesis protein PhzF family YP_003098362.1 592602 D 446462 CDS YP_003098363.1 256374703 8324709 593919..594908 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bcm:Bcenmc03_5299 LysR family transcriptional regulator; LysR family transcriptional regulator 594908 8324709 Amir_0550 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003098363.1 593919 D 446462 CDS YP_003098364.1 256374704 8324710 complement(594981..595796) 1 NC_013093.1 PFAM: NmrA family protein; short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_5100 NmrA family protein; NmrA family protein 595796 8324710 Amir_0551 Actinosynnema mirum DSM 43827 NmrA family protein YP_003098364.1 594981 R 446462 CDS YP_003098365.1 256374705 8324711 595883..596269 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: mxa:MXAN_5099 transcriptional regulator; HxlR family transcriptional regulator 596269 8324711 Amir_0552 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003098365.1 595883 D 446462 CDS YP_003098366.1 256374706 8324712 596361..597458 1 NC_013093.1 PFAM: AIG2 family protein; KEGG: pae:PA4164 hypothetical protein; AIG2 family protein 597458 8324712 Amir_0553 Actinosynnema mirum DSM 43827 AIG2 family protein YP_003098366.1 596361 D 446462 CDS YP_003098367.1 256374707 8324713 597634..598308 1 NC_013093.1 KEGG: rpc:RPC_3182 peptidase C14, caspase catalytic subunit P20; peptidase C14, caspase catalytic subunit P20 598308 8324713 Amir_0554 Actinosynnema mirum DSM 43827 peptidase C14, caspase catalytic subunit P20 YP_003098367.1 597634 D 446462 CDS YP_003098368.1 256374708 8324714 complement(598611..600047) 1 NC_013093.1 KEGG: hha:Hhal_1735 ABC transporter; hypothetical protein 600047 8324714 Amir_0555 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098368.1 598611 R 446462 CDS YP_003098369.1 256374709 8324715 complement(600103..601911) 1 NC_013093.1 PFAM: GTP-binding protein HSR1-related; KEGG: scl:sce0387 hypothetical protein; HSR1-like GTP-binding protein 601911 8324715 Amir_0556 Actinosynnema mirum DSM 43827 HSR1-like GTP-binding protein YP_003098369.1 600103 R 446462 CDS YP_003098370.1 256374710 8324716 complement(602010..602867) 1 NC_013093.1 KEGG: bcj:BCAS0321a hypothetical protein; hypothetical protein 602867 8324716 Amir_0557 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098370.1 602010 R 446462 CDS YP_003098371.1 256374711 8324717 603113..604432 1 NC_013093.1 KEGG: hha:Hhal_0145 heat shock protein 70; molecular chaperone-like protein 604432 8324717 Amir_0558 Actinosynnema mirum DSM 43827 molecular chaperone-like protein YP_003098371.1 603113 D 446462 CDS YP_003098372.1 256374712 8324718 604441..606807 1 NC_013093.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_3854 tetratricopeptide TPR_2 repeat protein; LuxR family transcriptional regulator 606807 8324718 Amir_0559 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003098372.1 604441 D 446462 CDS YP_003098373.1 256374713 8324719 complement(607000..607530) 1 NC_013093.1 KEGG: hch:HCH_05440 small integral membrane protein; small integral membrane protein 607530 8324719 Amir_0560 Actinosynnema mirum DSM 43827 small integral membrane protein YP_003098373.1 607000 R 446462 CDS YP_003098374.1 256374714 8324720 complement(607655..611689) 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce4551 protein kinase; hypothetical protein 611689 8324720 Amir_0561 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098374.1 607655 R 446462 CDS YP_003098375.1 256374715 8324721 complement(612309..612665) 1 NC_013093.1 KEGG: similar to zinc finger protein 607; hypothetical protein 612665 8324721 Amir_0562 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098375.1 612309 R 446462 CDS YP_003098376.1 256374716 8324722 612716..614470 1 NC_013093.1 PFAM: AlkA domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6205 regulatory protein Ada; AraC family transcriptional regulator 614470 8324722 Amir_0563 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003098376.1 612716 D 446462 CDS YP_003098377.1 256374717 8324723 614627..614773 1 NC_013093.1 hypothetical protein 614773 8324723 Amir_0564 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098377.1 614627 D 446462 CDS YP_003098378.1 256374718 8324724 complement(614904..615737) 1 NC_013093.1 PFAM: protein of unknown function DUF574; KEGG: scl:sce6070 hypothetical protein; hypothetical protein 615737 8324724 Amir_0565 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098378.1 614904 R 446462 CDS YP_003098379.1 256374719 8324725 615946..616830 1 NC_013093.1 hypothetical protein 616830 8324725 Amir_0566 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098379.1 615946 D 446462 CDS YP_003098380.1 256374720 8324726 616934..617221 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 617221 8324726 Amir_0567 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098380.1 616934 D 446462 CDS YP_003098381.1 256374721 8324727 617205..617510 1 NC_013093.1 hypothetical protein 617510 8324727 Amir_0568 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098381.1 617205 D 446462 CDS YP_003098382.1 256374722 8324728 complement(617909..619162) 1 NC_013093.1 KEGG: hypothetical LOC586091; membrane-bound lytic murein transglycosylase B-like protein 619162 8324728 Amir_0569 Actinosynnema mirum DSM 43827 membrane-bound lytic murein transglycosylase B-like protein YP_003098382.1 617909 R 446462 CDS YP_003098383.1 256374723 8324729 619562..625705 1 NC_013093.1 TIGRFAM: hypothetical protein; LPXTG- motif cell wall anchor domain protein; PFAM: Cna B domain protein; Pericardin like; KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein 625705 8324729 Amir_0570 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098383.1 619562 D 446462 CDS YP_003098384.1 256374724 8324731 626473..631002 1 NC_013093.1 TIGRFAM: YD repeat protein; KEGG: rso:RS05482 rhs-related transmembrane protein; YD repeat-containing protein 631002 8324731 Amir_0572 Actinosynnema mirum DSM 43827 YD repeat-containing protein YP_003098384.1 626473 D 446462 CDS YP_003098385.1 256374725 8324732 631013..631729 1 NC_013093.1 hypothetical protein 631729 8324732 Amir_0573 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098385.1 631013 D 446462 CDS YP_003098386.1 256374726 8324733 631738..632154 1 NC_013093.1 hypothetical protein 632154 8324733 Amir_0574 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098386.1 631738 D 446462 CDS YP_003098387.1 256374727 8324734 complement(632186..632659) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: bbt:BBta_3942 NUDIX-like hydrolase; NUDIX hydrolase 632659 8324734 Amir_0575 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003098387.1 632186 R 446462 CDS YP_003098388.1 256374728 8324735 633802..636642 1 NC_013093.1 PFAM: transcriptional activator domain; hypothetical protein; hypothetical protein; NB- ARC domain protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator 636642 8324735 Amir_0576 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003098388.1 633802 D 446462 CDS YP_003098389.1 256374729 8324736 636814..637278 1 NC_013093.1 KEGG: xcv:XCV0585 hypothetical protein; hypothetical protein 637278 8324736 Amir_0577 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098389.1 636814 D 446462 CDS YP_003098390.1 256374730 8324737 637607..637975 1 NC_013093.1 hypothetical protein 637975 8324737 Amir_0578 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098390.1 637607 D 446462 CDS YP_003098391.1 256374731 8324738 637962..638327 1 NC_013093.1 hypothetical protein 638327 8324738 Amir_0579 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098391.1 637962 D 446462 CDS YP_003098392.1 256374732 8324739 638324..639445 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 639445 8324739 Amir_0580 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098392.1 638324 D 446462 CDS YP_003098393.1 256374733 8324740 640633..641100 1 NC_013093.1 KEGG: pca:Pcar_0786 hypothetical protein; hypothetical protein 641100 8324740 Amir_0581 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098393.1 640633 D 446462 CDS YP_003098394.1 256374734 8324742 641901..642743 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 642743 8324742 Amir_0583 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003098394.1 641901 D 446462 CDS YP_003098395.1 256374735 8324743 complement(642722..642826) 1 NC_013093.1 hypothetical protein 642826 8324743 Amir_0584 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098395.1 642722 R 446462 CDS YP_003098396.1 256374736 8324744 complement(642843..643604) 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 643604 8324744 Amir_0585 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003098396.1 642843 R 446462 CDS YP_003098397.1 256374737 8324745 complement(643644..644723) 1 NC_013093.1 hypothetical protein 644723 8324745 Amir_0586 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098397.1 643644 R 446462 CDS YP_003098398.1 256374738 8324747 645528..646220 1 NC_013093.1 KEGG: ppr:PBPRA2228 carboxynorspermidine decarboxylase; hypothetical protein 646220 8324747 Amir_0588 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098398.1 645528 D 446462 CDS YP_003098399.1 256374739 8324748 646222..648237 1 NC_013093.1 hypothetical protein 648237 8324748 Amir_0589 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098399.1 646222 D 446462 CDS YP_003098400.1 256374740 8324749 complement(648541..649371) 1 NC_013093.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: swi:Swit_5329 phosphoadenosine phosphosulfate reductase; phosphoadenosine phosphosulfate reductase 649371 8324749 Amir_0590 Actinosynnema mirum DSM 43827 phosphoadenosine phosphosulfate reductase YP_003098400.1 648541 R 446462 CDS YP_003098401.1 256374741 8324750 complement(649368..652946) 1 NC_013093.1 KEGG: swi:Swit_5328 hypothetical protein; hypothetical protein 652946 8324750 Amir_0591 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098401.1 649368 R 446462 CDS YP_003098402.1 256374742 8324751 complement(652943..654061) 1 NC_013093.1 KEGG: swi:Swit_5327 hypothetical protein; hypothetical protein 654061 8324751 Amir_0592 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098402.1 652943 R 446462 CDS YP_003098403.1 256374743 8324752 complement(654119..655288) 1 NC_013093.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: afw:Anae109_1098 aminotransferase class V; class V aminotransferase 655288 8324752 Amir_0593 Actinosynnema mirum DSM 43827 class V aminotransferase YP_003098403.1 654119 R 446462 CDS YP_003098404.1 256374744 8324753 655826..657403 1 NC_013093.1 PFAM: type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: nha:Nham_3708 helicase-like; type III restriction protein res subunit 657403 8324753 Amir_0594 Actinosynnema mirum DSM 43827 type III restriction protein res subunit YP_003098404.1 655826 D 446462 CDS YP_003098405.1 256374745 8324754 657388..659277 1 NC_013093.1 KEGG: rpe:RPE_2170 hypothetical protein; hypothetical protein 659277 8324754 Amir_0595 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098405.1 657388 D 446462 CDS YP_003098406.1 256374746 8324755 659274..660161 1 NC_013093.1 KEGG: bbr:BB2173 bifunctional riboflavin kinase/FMN adenylyltransferase; hypothetical protein 660161 8324755 Amir_0596 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098406.1 659274 D 446462 CDS YP_003098407.1 256374747 8324757 661424..662275 1 NC_013093.1 PFAM: integrase family protein; KEGG: cjd:JJD26997_0344 phage integrase; integrase family protein 662275 8324757 Amir_0598 Actinosynnema mirum DSM 43827 integrase family protein YP_003098407.1 661424 D 446462 CDS YP_003098408.1 256374748 8324759 662795..663703 1 NC_013093.1 hypothetical protein 663703 8324759 Amir_0599 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098408.1 662795 D 446462 CDS YP_003098409.1 256374749 8324760 complement(663901..666813) 1 NC_013093.1 PFAM: peptidase S45 penicillin amidase; KEGG: abc:ACICU_01963 protein related to penicillin acylase; Penicillin amidase 666813 8324760 Amir_0600 Actinosynnema mirum DSM 43827 Penicillin amidase YP_003098409.1 663901 R 446462 CDS YP_003098410.1 256374750 8324761 667159..667806 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 667806 8324761 Amir_0601 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003098410.1 667159 D 446462 CDS YP_003098411.1 256374751 8324762 complement(667782..669695) 1 NC_013093.1 KEGG: mgm:Mmc1_3430 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 669695 8324762 Amir_0602 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003098411.1 667782 R 446462 CDS YP_003098412.1 256374752 8324763 complement(669772..670404) 1 NC_013093.1 TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; KEGG: ajs:Ajs_3177 cob(II)yrinic acid a,c-diamide reductase; cob(II)yrinic acid a,c-diamide reductase 670404 8324763 Amir_0603 Actinosynnema mirum DSM 43827 cob(II)yrinic acid a,c-diamide reductase YP_003098412.1 669772 R 446462 CDS YP_003098413.1 256374753 8324764 complement(670501..670734) 1 NC_013093.1 TIGRFAM: ribosomal protein S18; PFAM: ribosomal protein S18; KEGG: bha:BH4048 30S ribosomal protein S18; 30S ribosomal protein S18 670734 8324764 Amir_0604 Actinosynnema mirum DSM 43827 30S ribosomal protein S18 YP_003098413.1 670501 R 446462 CDS YP_003098414.1 256374754 8324765 complement(670746..671042) 1 NC_013093.1 PFAM: ribosomal protein S14; KEGG: ilo:IL1903 ribosomal protein S14; 30S ribosomal protein S14 671042 8324765 Amir_0605 Actinosynnema mirum DSM 43827 30S ribosomal protein S14 YP_003098414.1 670746 R 446462 CDS YP_003098415.1 256374755 8324766 complement(671044..671211) 1 NC_013093.1 TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: bpe:BP2050 50S ribosomal protein L33; 50S ribosomal protein L33 671211 8324766 Amir_0606 Actinosynnema mirum DSM 43827 50S ribosomal protein L33 YP_003098415.1 671044 R 446462 CDS YP_003098416.1 256374756 8324767 complement(671211..671450) 1 NC_013093.1 TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: tcx:Tcr_1918 ribosomal protein L28; 50S ribosomal protein L28 671450 8324767 Amir_0607 Actinosynnema mirum DSM 43827 50S ribosomal protein L28 YP_003098416.1 671211 R 446462 CDS YP_003098417.1 256374757 8324768 complement(671544..672197) 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: phosphoglycerate/bisphosphoglycerate mutase family protein; phosphoglycerate mutase 672197 8324768 Amir_0608 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003098417.1 671544 R 446462 CDS YP_003098418.1 256374758 8324769 672244..672594 1 NC_013093.1 PFAM: ethyl tert-butyl ether degradation EthD; KEGG: bha:BH0200 hypothetical protein; ethyl tert-butyl ether degradation protein EthD 672594 8324769 Amir_0609 Actinosynnema mirum DSM 43827 ethyl tert-butyl ether degradation protein EthD YP_003098418.1 672244 D 446462 CDS YP_003098419.1 256374759 8324770 672591..673421 1 NC_013093.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: scl:sce7905 hypothetical protein; 3-hydroxyacyl-CoA dehydrogenase 673421 8324770 Amir_0610 Actinosynnema mirum DSM 43827 3-hydroxyacyl-CoA dehydrogenase YP_003098419.1 672591 D 446462 CDS YP_003098420.1 256374760 8324771 673500..674636 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_5851 acetyltransferase, GNAT family; GCN5-like N-acetyltransferase 674636 8324771 Amir_0611 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003098420.1 673500 D 446462 CDS YP_003098421.1 256374761 8324772 674727..675413 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfu:Sfum_2007 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 675413 8324772 Amir_0612 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003098421.1 674727 D 446462 CDS YP_003098422.1 256374762 8324773 675410..676840 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sfu:Sfum_2006 integral membrane sensor signal transduction histidine kinase; histidine kinase 676840 8324773 Amir_0613 Actinosynnema mirum DSM 43827 histidine kinase YP_003098422.1 675410 D 446462 CDS YP_003098423.1 256374763 8324774 complement(676917..677777) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_2010 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 677777 8324774 Amir_0614 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098423.1 676917 R 446462 CDS YP_003098424.1 256374764 8324775 complement(677774..678682) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL120384 permease component of ABC transporter; ABC transporter inner membrane protein 678682 8324775 Amir_0615 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098424.1 677774 R 446462 CDS YP_003098425.1 256374765 8324776 complement(678688..679986) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: sugar ABC transporter; family 1 extracellular solute-binding protein 679986 8324776 Amir_0616 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003098425.1 678688 R 446462 CDS YP_003098426.1 256374766 8324777 680221..682254 1 NC_013093.1 PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; beta-galactosidase domain protein; KEGG: bha:BH3701 beta-galactosidase; beta-galactosidase 682254 8324777 Amir_0617 Actinosynnema mirum DSM 43827 beta-galactosidase YP_003098426.1 680221 D 446462 CDS YP_003098427.1 256374767 8324778 682257..683057 1 NC_013093.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: glpRb; glycerol-3-phosphate transcriptional regulator protein; DeoR family transcriptional regulator 683057 8324778 Amir_0618 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003098427.1 682257 D 446462 CDS YP_003098428.1 256374768 8324779 683054..684148 1 NC_013093.1 KEGG: nmu:Nmul_A1939 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; galactose-1-phosphate uridylyltransferase 684148 8324779 Amir_0619 Actinosynnema mirum DSM 43827 galactose-1-phosphate uridylyltransferase YP_003098428.1 683054 D 446462 CDS YP_003098429.1 256374769 8324780 684324..686348 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; KEGG: gox:GOX0798 serine protease; peptidase S1 and S6 chymotrypsin/Hap 686348 8324780 Amir_0620 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003098429.1 684324 D 446462 CDS YP_003098430.1 256374770 8324781 complement(686531..686635) 1 NC_013093.1 hypothetical protein 686635 8324781 Amir_0621 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098430.1 686531 R 446462 CDS YP_003098431.1 256374771 8324782 686868..687368 1 NC_013093.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: sfu:Sfum_0070 molybdenum cofactor synthesis domain; molybdenum cofactor synthesis domain-containing protein 687368 8324782 Amir_0622 Actinosynnema mirum DSM 43827 molybdenum cofactor synthesis domain-containing protein YP_003098431.1 686868 D 446462 CDS YP_003098432.1 256374772 8324783 687365..687535 1 NC_013093.1 hypothetical protein 687535 8324783 Amir_0623 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098432.1 687365 D 446462 CDS YP_003098433.1 256374773 8324784 complement(688177..688707) 1 NC_013093.1 TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; KEGG: spe:Spro_4515 large-conductance mechanosensitive channel; large conductance mechanosensitive channel protein 688707 8324784 Amir_0624 Actinosynnema mirum DSM 43827 large conductance mechanosensitive channel protein YP_003098433.1 688177 R 446462 CDS YP_003098434.1 256374774 8324785 complement(689131..689706) 1 NC_013093.1 PFAM: SAF domain protein; KEGG: dvm:DvMF_2742 Flp pilus assembly protein CpaB; SAF domain-containing protein 689706 8324785 Amir_0625 Actinosynnema mirum DSM 43827 SAF domain-containing protein YP_003098434.1 689131 R 446462 CDS YP_003098435.1 256374775 8324786 complement(689796..690101) 1 NC_013093.1 TIGRFAM: regulatory protein, FmdB family; KEGG: scl:sce1745 hypothetical protein; FmdB family regulatory protein 690101 8324786 Amir_0626 Actinosynnema mirum DSM 43827 FmdB family regulatory protein YP_003098435.1 689796 R 446462 CDS YP_003098436.1 256374776 8324787 complement(690203..690769) 1 NC_013093.1 TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: ade:Adeh_1046 5-formyltetrahydrofolate cyclo- ligase; 5-formyltetrahydrofolate cyclo-ligase 690769 8324787 Amir_0627 Actinosynnema mirum DSM 43827 5-formyltetrahydrofolate cyclo-ligase YP_003098436.1 690203 R 446462 CDS YP_003098437.1 256374777 8324788 690808..691689 1 NC_013093.1 PFAM: Nucleotidyl transferase; KEGG: mag:amb4451 UDP-glucose pyrophosphorylase; Nucleotidyl transferase 691689 8324788 Amir_0628 Actinosynnema mirum DSM 43827 Nucleotidyl transferase YP_003098437.1 690808 D 446462 CDS YP_003098438.1 256374778 8324789 691722..692945 1 NC_013093.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: hha:Hhal_0242 molybdenum cofactor synthesis domain; molybdenum cofactor synthesis domain-containing protein 692945 8324789 Amir_0629 Actinosynnema mirum DSM 43827 molybdenum cofactor synthesis domain-containing protein YP_003098438.1 691722 D 446462 CDS YP_003098439.1 256374779 8324790 692949..693608 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: smd:Smed_0534 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 693608 8324790 Amir_0630 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003098439.1 692949 D 446462 CDS YP_003098440.1 256374780 8324791 693762..694406 1 NC_013093.1 hypothetical protein 694406 8324791 Amir_0631 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098440.1 693762 D 446462 CDS YP_003098441.1 256374781 8324793 694897..695607 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: nwi:Nwi_3032 Crp family transcriptional regulator; Crp/Fnr family transcriptional regulator 695607 8324793 Amir_0632 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003098441.1 694897 D 446462 CDS YP_003098442.1 256374782 8324794 695634..696263 1 NC_013093.1 hypothetical protein 696263 8324794 Amir_0633 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098442.1 695634 D 446462 CDS YP_003098443.1 256374783 8324795 696274..699279 1 NC_013093.1 PFAM: UvrD/REP helicase; KEGG: scl:sce3530 ATP-dependent DNA helicase; UvrD/REP helicase 699279 8324795 Amir_0634 Actinosynnema mirum DSM 43827 UvrD/REP helicase YP_003098443.1 696274 D 446462 CDS YP_003098444.1 256374784 8324796 699424..701589 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_4017 serine/threonine protein kinase; serine/threonine protein kinase 701589 8324796 Amir_0635 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003098444.1 699424 D 446462 CDS YP_003098445.1 256374785 8324797 complement(701659..703230) 1 NC_013093.1 PFAM: glycosyl transferase family 39; KEGG: glycosyl transferase family 39; glycosyl transferase family protein 703230 8324797 Amir_0636 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003098445.1 701659 R 446462 CDS YP_003098446.1 256374786 8324798 703255..704100 1 NC_013093.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tgr:Tgr7_0758 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase 704100 8324798 Amir_0637 Actinosynnema mirum DSM 43827 uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_003098446.1 703255 D 446462 CDS YP_003098447.1 256374787 8324799 complement(704087..704491) 1 NC_013093.1 hypothetical protein 704491 8324799 Amir_0638 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098447.1 704087 R 446462 CDS YP_003098448.1 256374788 8324800 complement(704551..705114) 1 NC_013093.1 hypothetical protein 705114 8324800 Amir_0639 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098448.1 704551 R 446462 CDS YP_003098449.1 256374789 8324801 complement(705189..705563) 1 NC_013093.1 hypothetical protein 705563 8324801 Amir_0640 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098449.1 705189 R 446462 CDS YP_003098450.1 256374790 8324802 complement(705567..706187) 1 NC_013093.1 hypothetical protein 706187 8324802 Amir_0641 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098450.1 705567 R 446462 CDS YP_003098451.1 256374791 8324803 706283..708073 1 NC_013093.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 708073 8324803 Amir_0642 Actinosynnema mirum DSM 43827 methionyl-tRNA synthetase YP_003098451.1 706283 D 446462 CDS YP_003098452.1 256374792 8324804 708124..708894 1 NC_013093.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: bcz:BCZK0035 TatD related DNase; hydrolase, TatD family 708894 8324804 Amir_0643 Actinosynnema mirum DSM 43827 hydrolase, TatD family YP_003098452.1 708124 D 446462 CDS YP_003098453.1 256374793 8324805 709193..710614 1 NC_013093.1 PFAM: transglycosylase domain protein; protein of unknown function DUF348; G5 domain protein; KEGG: bsu:BSU00400 hypothetical protein; transglycosylase domain-containing protein 710614 8324805 Amir_0644 Actinosynnema mirum DSM 43827 transglycosylase domain-containing protein YP_003098453.1 709193 D 446462 CDS YP_003098454.1 256374794 8324806 710778..711674 1 NC_013093.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 711674 ksgA 8324806 ksgA Actinosynnema mirum DSM 43827 dimethyladenosine transferase YP_003098454.1 710778 D 446462 CDS YP_003098455.1 256374795 8324807 712071..713072 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: rce:RC1_3351 ABC transporter, ATP-binding protein; ABC transporter 713072 8324807 Amir_0646 Actinosynnema mirum DSM 43827 ABC transporter YP_003098455.1 712071 D 446462 CDS YP_003098456.1 256374796 8324808 713069..713752 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vsp:VS_2383 probable D-methionine transport system permease protein MetI; D-methionine ABC transporter permease 713752 8324808 Amir_0647 Actinosynnema mirum DSM 43827 D-methionine ABC transporter permease YP_003098456.1 713069 D 446462 CDS YP_003098457.1 256374797 8324809 713813..714634 1 NC_013093.1 PFAM: NLPA lipoprotein; KEGG: pst:PSPTO_5216 NlpA family lipoprotein; NLPA lipoprotein 714634 8324809 Amir_0648 Actinosynnema mirum DSM 43827 NLPA lipoprotein YP_003098457.1 713813 D 446462 CDS YP_003098458.1 256374798 8324810 714738..715703 1 NC_013093.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 715703 8324810 Amir_0649 Actinosynnema mirum DSM 43827 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_003098458.1 714738 D 446462 CDS YP_003098459.1 256374799 8324811 715722..717494 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcb:BCB4264_A2173 ABC transporter, ATP- binding protein; ABC transporter 717494 8324811 Amir_0650 Actinosynnema mirum DSM 43827 ABC transporter YP_003098459.1 715722 D 446462 CDS YP_003098460.1 256374800 8324812 complement(717693..719588) 1 NC_013093.1 KEGG: WIP homolog; hypothetical protein 719588 8324812 Amir_0651 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098460.1 717693 R 446462 CDS YP_003098461.1 256374801 8324813 719692..721332 1 NC_013093.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 721332 8324813 Amir_0652 Actinosynnema mirum DSM 43827 long-chain-fatty-acid--CoA ligase YP_003098461.1 719692 D 446462 CDS YP_003098462.1 256374802 8324814 complement(721456..722025) 1 NC_013093.1 KEGG: mxa:MXAN_5077 peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 722025 8324814 Amir_0653 Actinosynnema mirum DSM 43827 peptidyl-tRNA hydrolase YP_003098462.1 721456 R 446462 CDS YP_003098463.1 256374803 8324815 complement(722015..722497) 1 NC_013093.1 hypothetical protein 722497 8324815 Amir_0654 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098463.1 722015 R 446462 CDS YP_003098464.1 256374804 8324816 complement(722583..723176) 1 NC_013093.1 TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: ribosomal protein L25; KEGG: aeh:Mlg_0284 50S ribosomal protein L25P; ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 723176 8324816 Amir_0655 Actinosynnema mirum DSM 43827 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 YP_003098464.1 722583 R 446462 CDS YP_003098465.1 256374805 8324817 complement(723726..724697) 1 NC_013093.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 724697 8324817 Amir_0656 Actinosynnema mirum DSM 43827 ribose-phosphate pyrophosphokinase YP_003098465.1 723726 R 446462 CDS YP_003098466.1 256374806 8324818 complement(724714..726189) 1 NC_013093.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: glo:Glov_0702 UDP-N-acetylglucosamine pyrophosphorylase; UDP-N-acetylglucosamine pyrophosphorylase 726189 8324818 Amir_0657 Actinosynnema mirum DSM 43827 UDP-N-acetylglucosamine pyrophosphorylase YP_003098466.1 724714 R 446462 CDS YP_003098467.1 256374807 8324819 complement(726256..727899) 1 NC_013093.1 KEGG: hha:Hhal_1304 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 727899 8324819 Amir_0658 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003098467.1 726256 R 446462 CDS YP_003098468.1 256374808 8324821 complement(728200..729366) 1 NC_013093.1 KEGG: hne:HNE_1191 hypothetical protein; dipeptidylaminopeptidase/acylaminoacyl- peptidase-like protein 729366 8324821 Amir_0659 Actinosynnema mirum DSM 43827 dipeptidylaminopeptidase/acylaminoacyl- peptidase-like protein YP_003098468.1 728200 R 446462 CDS YP_003098469.1 256374809 8324822 729521..730510 1 NC_013093.1 PFAM: fatty acid desaturase; KEGG: pfl:PFL_0262 fatty acid desaturase family proteiin; stearoyl-CoA 9-desaturase 730510 8324822 Amir_0660 Actinosynnema mirum DSM 43827 stearoyl-CoA 9-desaturase YP_003098469.1 729521 D 446462 CDS YP_003098470.1 256374810 8324823 730614..731231 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mxa:MXAN_5545 transcriptional regulator, TetR family; TetR family transcriptional regulator 731231 8324823 Amir_0661 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098470.1 730614 D 446462 CDS YP_003098471.1 256374811 8324824 731283..731810 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 731810 8324824 Amir_0662 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098471.1 731283 D 446462 CDS YP_003098472.1 256374812 8324825 731868..732971 1 NC_013093.1 PFAM: glucose sorbosone dehydrogenase; KEGG: ppd:Ppro_1990 hypothetical protein; glucose sorbosone dehydrogenase 732971 8324825 Amir_0663 Actinosynnema mirum DSM 43827 glucose sorbosone dehydrogenase YP_003098472.1 731868 D 446462 CDS YP_003098473.1 256374813 8324826 complement(732955..733863) 1 NC_013093.1 hypothetical protein 733863 8324826 Amir_0664 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098473.1 732955 R 446462 CDS YP_003098474.1 256374814 8324827 734160..737723 1 NC_013093.1 KEGG: gsu:GSU0017 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: transcription factor CarD; helicase domain protein; TRCF domain protein; DEAD/DEAH box helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; transcription-repair coupling factor 737723 8324827 Amir_0665 Actinosynnema mirum DSM 43827 transcription-repair coupling factor YP_003098474.1 734160 D 446462 CDS YP_003098475.1 256374815 8324828 737737..738678 1 NC_013093.1 hypothetical protein 738678 8324828 Amir_0666 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098475.1 737737 D 446462 CDS YP_003098476.1 256374816 8324829 738792..739778 1 NC_013093.1 TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: rce:RC1_0140 MazG family protein; MazG family protein 739778 8324829 Amir_0667 Actinosynnema mirum DSM 43827 MazG family protein YP_003098476.1 738792 D 446462 CDS YP_003098477.1 256374817 8324830 740007..743216 1 NC_013093.1 PFAM: peptidase S41; SMART: peptidase S41; KEGG: swd:Swoo_3891 peptidase S41; peptidase S41 743216 8324830 Amir_0668 Actinosynnema mirum DSM 43827 peptidase S41 YP_003098477.1 740007 D 446462 CDS YP_003098478.1 256374818 8324831 743441..744385 1 NC_013093.1 KEGG: scl:sce1066 hypothetical protein; membrane-bound lytic murein transglycosylase B-like protein 744385 8324831 Amir_0669 Actinosynnema mirum DSM 43827 membrane-bound lytic murein transglycosylase B-like protein YP_003098478.1 743441 D 446462 CDS YP_003098479.1 256374819 8324832 complement(744530..744913) 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: azc:AZC_2926 hypothetical protein; hypothetical protein 744913 8324832 Amir_0670 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098479.1 744530 R 446462 CDS YP_003098480.1 256374820 8324833 745109..746395 1 NC_013093.1 KEGG: nar:Saro_2223 enolase; TIGRFAM: enolase; PFAM: enolase; enolase 746395 8324833 Amir_0671 Actinosynnema mirum DSM 43827 enolase YP_003098480.1 745109 D 446462 CDS YP_003098481.1 256374821 8324834 746791..747156 1 NC_013093.1 PFAM: septum formation initiator; septum formation initiator 747156 8324834 Amir_0672 Actinosynnema mirum DSM 43827 septum formation initiator YP_003098481.1 746791 D 446462 CDS YP_003098482.1 256374822 8324835 747153..747650 1 NC_013093.1 PFAM: protein of unknown function DUF501; KEGG: csa:Csal_3040 hypothetical protein; hypothetical protein 747650 8324835 Amir_0673 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098482.1 747153 D 446462 CDS YP_003098483.1 256374823 8324836 747861..749165 1 NC_013093.1 KEGG: GI22470 gene product from transcript GI22470- RA; membrane-bound lytic murein transglycosylase B-like protein 749165 8324836 Amir_0674 Actinosynnema mirum DSM 43827 membrane-bound lytic murein transglycosylase B-like protein YP_003098483.1 747861 D 446462 CDS YP_003098484.1 256374824 8324837 749617..750579 1 NC_013093.1 PFAM: Ppx/GppA phosphatase; KEGG: scl:sce1705 hypothetical protein; Ppx/GppA phosphatase 750579 8324837 Amir_0675 Actinosynnema mirum DSM 43827 Ppx/GppA phosphatase YP_003098484.1 749617 D 446462 CDS YP_003098485.1 256374825 8324838 750779..752404 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: bsu:BSU11430 oligopeptide ABC transporter (binding protein); 4-phytase 752404 8324838 Amir_0676 Actinosynnema mirum DSM 43827 4-phytase YP_003098485.1 750779 D 446462 CDS YP_003098486.1 256374826 8324839 752475..753401 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dde:Dde_1184 dipeptide ABC transporter, permease protein; dipeptide ABC transporter permease 753401 8324839 Amir_0677 Actinosynnema mirum DSM 43827 dipeptide ABC transporter permease YP_003098486.1 752475 D 446462 CDS YP_003098487.1 256374827 8324840 753394..754317 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bpt:Bpet2850 ABC transporter inner membrane protein; ABC transporter inner membrane protein 754317 8324840 Amir_0678 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098487.1 753394 D 446462 CDS YP_003098488.1 256374828 8324841 754330..755313 1 NC_013093.1 KEGG: mrd:Mrad2831_4369 oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 755313 8324841 Amir_0679 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003098488.1 754330 D 446462 CDS YP_003098489.1 256374829 8324842 755306..756304 1 NC_013093.1 KEGG: bbt:BBta_6951 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 756304 8324842 Amir_0680 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003098489.1 755306 D 446462 CDS YP_003098490.1 256374830 8324843 complement(756356..757837) 1 NC_013093.1 PFAM: peptidase S10 serine carboxypeptidase; KEGG: gur:Gura_2114 peptidase S10, serine carboxypeptidase; peptidase S10 serine carboxypeptidase 757837 8324843 Amir_0681 Actinosynnema mirum DSM 43827 peptidase S10 serine carboxypeptidase YP_003098490.1 756356 R 446462 CDS YP_003098491.1 256374831 8324844 757874..758704 1 NC_013093.1 PFAM: uracil-DNA glycosylase; KEGG: ank:AnaeK_3689 uracil-DNA glycosylase protein; uracil-DNA glycosylase 758704 8324844 Amir_0682 Actinosynnema mirum DSM 43827 uracil-DNA glycosylase YP_003098491.1 757874 D 446462 CDS YP_003098492.1 256374832 8324845 758848..759519 1 NC_013093.1 KEGG: gur:Gura_0189 transglutaminase domain- containing protein; hypothetical protein 759519 8324845 Amir_0683 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098492.1 758848 D 446462 CDS YP_003098493.1 256374833 8324846 759516..759977 1 NC_013093.1 hypothetical protein 759977 8324846 Amir_0684 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098493.1 759516 D 446462 CDS YP_003098494.1 256374834 8324847 759974..760927 1 NC_013093.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: sml:Smlt4485 ATPase; ATPase 760927 8324847 Amir_0685 Actinosynnema mirum DSM 43827 ATPase YP_003098494.1 759974 D 446462 CDS YP_003098495.1 256374835 8324848 760924..762228 1 NC_013093.1 PFAM: protein of unknown function DUF58; KEGG: mmr:Mmar10_2677 hypothetical protein; hypothetical protein 762228 8324848 Amir_0686 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098495.1 760924 D 446462 CDS YP_003098496.1 256374836 8324849 762265..763008 1 NC_013093.1 KEGG: GK24882 gene product from transcript GK24882- RA; hypothetical protein 763008 8324849 Amir_0687 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098496.1 762265 D 446462 CDS YP_003098497.1 256374837 8324850 763157..764482 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: rsh:Rsph17029_3442 cyclic nucleotide- regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 764482 8324850 Amir_0688 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003098497.1 763157 D 446462 CDS YP_003098498.1 256374838 8324851 764710..764832 1 NC_013093.1 hypothetical protein 764832 8324851 Amir_0689 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098498.1 764710 D 446462 CDS YP_003098499.1 256374839 8324852 764862..766781 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 766781 8324852 Amir_0690 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098499.1 764862 D 446462 CDS YP_003098500.1 256374840 8324853 766762..767832 1 NC_013093.1 PFAM: nitroreductase; KEGG: bcz:pE33L466_0413 NADH oxidase; nitroreductase 767832 8324853 Amir_0691 Actinosynnema mirum DSM 43827 nitroreductase YP_003098500.1 766762 D 446462 CDS YP_003098501.1 256374841 8324855 complement(768231..769874) 1 NC_013093.1 PFAM: protein of unknown function DUF885; KEGG: nar:Saro_2356 hypothetical protein; hypothetical protein 769874 8324855 Amir_0692 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098501.1 768231 R 446462 CDS YP_003098502.1 256374842 8324856 770041..770664 1 NC_013093.1 KEGG: bid:Bind_2941 hypothetical protein; hypothetical protein 770664 8324856 Amir_0693 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098502.1 770041 D 446462 CDS YP_003098503.1 256374843 8324857 complement(770728..771897) 1 NC_013093.1 KEGG: scl:sce7515 hypothetical protein; hypothetical protein 771897 8324857 Amir_0694 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098503.1 770728 R 446462 CDS YP_003098504.1 256374844 8324858 complement(771975..772661) 1 NC_013093.1 PFAM: peptidase C60 sortase A and B; peptidase C60 sortase A and B 772661 8324858 Amir_0695 Actinosynnema mirum DSM 43827 peptidase C60 sortase A and B YP_003098504.1 771975 R 446462 CDS YP_003098505.1 256374845 8324859 complement(772688..774055) 1 NC_013093.1 KEGG: bmn:BMA10247_0315 cell division protein FtsK; hypothetical protein 774055 8324859 Amir_0696 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098505.1 772688 R 446462 CDS YP_003098506.1 256374846 8324860 774333..775142 1 NC_013093.1 PFAM: protein of unknown function DUF1112; KEGG: xfa:XF2760 hypothetical protein; hypothetical protein 775142 8324860 Amir_0697 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098506.1 774333 D 446462 CDS YP_003098507.1 256374847 8324861 complement(775325..775558) 1 NC_013093.1 hypothetical protein 775558 8324861 Amir_0698 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098507.1 775325 R 446462 CDS YP_003098508.1 256374848 8324862 complement(775719..776939) 1 NC_013093.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 776939 8324862 Amir_0699 Actinosynnema mirum DSM 43827 acetyl-CoA acetyltransferase YP_003098508.1 775719 R 446462 CDS YP_003098509.1 256374849 8324863 777141..778511 1 NC_013093.1 KEGG: afw:Anae109_3846 pyridoxal-5'-phosphate- dependent protein beta subunit; TIGRFAM: cystathionine beta-synthase; PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein; cystathionine beta-synthase 778511 8324863 Amir_0700 Actinosynnema mirum DSM 43827 cystathionine beta-synthase YP_003098509.1 777141 D 446462 CDS YP_003098510.1 256374850 8324864 778707..779828 1 NC_013093.1 PFAM: hypothetical protein; KEGG: GI11778 gene product from transcript GI11778- RA; hypothetical protein 779828 8324864 Amir_0701 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098510.1 778707 D 446462 CDS YP_003098511.1 256374851 8324865 780021..781172 1 NC_013093.1 PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase; cystathionine gamma-synthase 781172 8324865 Amir_0702 Actinosynnema mirum DSM 43827 cystathionine gamma-synthase YP_003098511.1 780021 D 446462 CDS YP_003098512.1 256374852 8324866 complement(781277..781549) 1 NC_013093.1 KEGG: scl:sce7470 hypothetical protein; hypothetical protein 781549 8324866 Amir_0703 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098512.1 781277 R 446462 CDS YP_003098513.1 256374853 8324867 complement(781577..781801) 1 NC_013093.1 hypothetical protein 781801 8324867 Amir_0704 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098513.1 781577 R 446462 CDS YP_003098514.1 256374854 8324868 complement(781935..783116) 1 NC_013093.1 KEGG: bcy:Bcer98_0228 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 4-hydroxyphenylpyruvate dioxygenase 783116 8324868 Amir_0705 Actinosynnema mirum DSM 43827 4-hydroxyphenylpyruvate dioxygenase YP_003098514.1 781935 R 446462 CDS YP_003098515.1 256374855 8324869 783192..783713 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: ppg:PputGB1_0412 AsnC family transcriptional regulator; AsnC family transcriptional regulator 783713 8324869 Amir_0706 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003098515.1 783192 D 446462 CDS YP_003098516.1 256374856 8324870 complement(783930..784418) 1 NC_013093.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: wol:WD0654 transcription elongation factor GreA; transcription elongation factor GreA 784418 8324870 Amir_0707 Actinosynnema mirum DSM 43827 transcription elongation factor GreA YP_003098516.1 783930 R 446462 CDS YP_003098517.1 256374857 8324871 complement(784632..785051) 1 NC_013093.1 hypothetical protein 785051 8324871 Amir_0708 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098517.1 784632 R 446462 CDS YP_003098518.1 256374858 8324872 785161..786042 1 NC_013093.1 TIGRFAM: mycothiol conjugate amidase Mca; PFAM: LmbE family protein; KEGG: aba:Acid345_2880 LmbE-like protein; mycothiol conjugate amidase Mca 786042 8324872 Amir_0709 Actinosynnema mirum DSM 43827 mycothiol conjugate amidase Mca YP_003098518.1 785161 D 446462 CDS YP_003098519.1 256374859 8324873 786039..786398 1 NC_013093.1 KEGG: SAT2; serine O-acetyl transferase; K00640 serine O-acetyltransferase; hypothetical protein 786398 8324873 Amir_0710 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098519.1 786039 D 446462 CDS YP_003098520.1 256374860 8324874 complement(786435..786995) 1 NC_013093.1 PFAM: protein of unknown function DUF1526; KEGG: rru:Rru_A1986 hypothetical protein; hypothetical protein 786995 8324874 Amir_0711 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098520.1 786435 R 446462 CDS YP_003098521.1 256374861 8324875 787541..789514 1 NC_013093.1 PFAM: protein of unknown function DUF255; KEGG: xau:Xaut_1832 hypothetical protein; hypothetical protein 789514 8324875 Amir_0712 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098521.1 787541 D 446462 CDS YP_003098522.1 256374862 8324876 complement(789566..790243) 1 NC_013093.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: afw:Anae109_1200 hemolysin III family channel protein; channel protein, hemolysin III family 790243 8324876 Amir_0713 Actinosynnema mirum DSM 43827 channel protein, hemolysin III family YP_003098522.1 789566 R 446462 CDS YP_003098523.1 256374863 8324877 790326..791105 1 NC_013093.1 KEGG: bcj:BCAM2067 undecaprenyl pyrophosphate synthetase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase 791105 8324877 Amir_0714 Actinosynnema mirum DSM 43827 undecaprenyl diphosphate synthase YP_003098523.1 790326 D 446462 CDS YP_003098524.1 256374864 8324878 complement(791335..791661) 1 NC_013093.1 KEGG: abb:ABBFA_000474 outer membrane protein A precursor (190 kDa antigen); outer membrane protein A (190 kDa antigen) 791661 8324878 Amir_0715 Actinosynnema mirum DSM 43827 outer membrane protein A (190 kDa antigen) YP_003098524.1 791335 R 446462 CDS YP_003098525.1 256374865 8324879 791836..793074 1 NC_013093.1 KEGG: sal:Sala_0599 hypothetical protein; hypothetical protein 793074 8324879 Amir_0716 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098525.1 791836 D 446462 CDS YP_003098526.1 256374866 8324880 793447..794823 1 NC_013093.1 PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; KEGG: dal:Dalk_3397 PhoH family protein; PhoH family protein 794823 8324880 Amir_0717 Actinosynnema mirum DSM 43827 PhoH family protein YP_003098526.1 793447 D 446462 CDS YP_003098527.1 256374867 8324881 complement(794926..796359) 1 NC_013093.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 796359 8324881 Amir_0718 Actinosynnema mirum DSM 43827 inosine 5-monophosphate dehydrogenase YP_003098527.1 794926 R 446462 CDS YP_003098528.1 256374868 8324882 complement(796372..797985) 1 NC_013093.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase 797985 ligB 8324882 ligB Actinosynnema mirum DSM 43827 ATP-dependent DNA ligase YP_003098528.1 796372 R 446462 CDS YP_003098529.1 256374869 8324883 complement(798086..799480) 1 NC_013093.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 799480 fumC 8324883 fumC Actinosynnema mirum DSM 43827 fumarate hydratase YP_003098529.1 798086 R 446462 CDS YP_003098530.1 256374870 8324884 799546..800517 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bha:BH3408 thioredoxin reductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 800517 8324884 Amir_0721 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003098530.1 799546 D 446462 CDS YP_003098531.1 256374871 8324885 complement(800609..801043) 1 NC_013093.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: xca:xccb100_2984 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 801043 8324885 Amir_0722 Actinosynnema mirum DSM 43827 ErfK/YbiS/YcfS/YnhG family protein YP_003098531.1 800609 R 446462 CDS YP_003098532.1 256374872 8324886 complement(801210..801974) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap 801974 8324886 Amir_0723 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003098532.1 801210 R 446462 CDS YP_003098533.1 256374873 8324887 complement(802130..803182) 1 NC_013093.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 803182 glpX 8324887 glpX Actinosynnema mirum DSM 43827 fructose 1,6-bisphosphatase II YP_003098533.1 802130 R 446462 CDS YP_003098534.1 256374874 8324888 complement(803231..803440) 1 NC_013093.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: exonuclease VII small subunit; KEGG: AGAP012846-PA; exodeoxyribonuclease VII, small subunit 803440 8324888 Amir_0725 Actinosynnema mirum DSM 43827 exodeoxyribonuclease VII, small subunit YP_003098534.1 803231 R 446462 CDS YP_003098535.1 256374875 8324889 complement(803437..803847) 1 NC_013093.1 KEGG: scl:sce2186 hypothetical protein; hypothetical protein 803847 8324889 Amir_0726 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098535.1 803437 R 446462 CDS YP_003098536.1 256374876 8324890 complement(803828..805090) 1 NC_013093.1 KEGG: hha:Hhal_1683 exodeoxyribonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: exonuclease VII large subunit; nucleic acid binding OB-fold tRNA/helicase-type; exodeoxyribonuclease VII, large subunit 805090 8324890 Amir_0727 Actinosynnema mirum DSM 43827 exodeoxyribonuclease VII, large subunit YP_003098536.1 803828 R 446462 CDS YP_003098537.1 256374877 8324891 complement(805087..805716) 1 NC_013093.1 KEGG: GM22731 gene product from transcript GM22731- RA; hypothetical protein 805716 8324891 Amir_0728 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098537.1 805087 R 446462 CDS YP_003098538.1 256374878 8324892 805781..806725 1 NC_013093.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 806725 ispH 8324892 ispH Actinosynnema mirum DSM 43827 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_003098538.1 805781 D 446462 CDS YP_003098539.1 256374879 8324893 complement(807024..807767) 1 NC_013093.1 KEGG: DNA helicase (SGS1 homologue); K03654 ATP- dependent DNA helicase RecQ; hypothetical protein 807767 8324893 Amir_0730 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098539.1 807024 R 446462 CDS YP_003098540.1 256374880 8324894 complement(807869..808810) 1 NC_013093.1 PFAM: protein of unknown function DUF195; KEGG: afw:Anae109_0527 hypothetical protein; hypothetical protein 808810 8324894 Amir_0731 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098540.1 807869 R 446462 CDS YP_003098541.1 256374881 8324895 808913..810061 1 NC_013093.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: afw:Anae109_2145 nuclease SbcCD, D subunit; nuclease SbcCD, D subunit 810061 8324895 Amir_0732 Actinosynnema mirum DSM 43827 nuclease SbcCD, D subunit YP_003098541.1 808913 D 446462 CDS YP_003098542.1 256374882 8324896 810058..812946 1 NC_013093.1 KEGG: afw:Anae109_2144 DNA repair exonuclease, SbcC; DNA repair exonuclease, SbcC 812946 8324896 Amir_0733 Actinosynnema mirum DSM 43827 DNA repair exonuclease, SbcC YP_003098542.1 810058 D 446462 CDS YP_003098543.1 256374883 8324897 complement(812974..813468) 1 NC_013093.1 TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; KEGG: sus:Acid_4002 methylated-DNA--protein- cysteine methyltransferase; methylated-DNA/protein- cysteinemethyltransferase 813468 8324897 Amir_0734 Actinosynnema mirum DSM 43827 methylated-DNA/protein- cysteinemethyltransferase YP_003098543.1 812974 R 446462 CDS YP_003098544.1 256374884 8324898 complement(813465..814790) 1 NC_013093.1 KEGG: scl:sce6205 regulatory protein Ada; PFAM: AlkA domain protein; Ada metal-binding domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; AraC family transcriptional regulator 814790 8324898 Amir_0735 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003098544.1 813465 R 446462 CDS YP_003098545.1 256374885 8324899 814869..815948 1 NC_013093.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 815948 8324899 Amir_0736 Actinosynnema mirum DSM 43827 GTP-dependent nucleic acid-binding protein EngD YP_003098545.1 814869 D 446462 CDS YP_003098546.1 256374886 8324900 816499..816972 1 NC_013093.1 hypothetical protein 816972 8324900 Amir_0737 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098546.1 816499 D 446462 CDS YP_003098547.1 256374887 8324901 816990..817316 1 NC_013093.1 hypothetical protein 817316 8324901 Amir_0738 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098547.1 816990 D 446462 CDS YP_003098548.1 256374888 8324902 complement(817485..818147) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 818147 8324902 Amir_0739 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098548.1 817485 R 446462 CDS YP_003098549.1 256374889 8324903 complement(818390..818743) 1 NC_013093.1 hypothetical protein 818743 8324903 Amir_0740 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098549.1 818390 R 446462 CDS YP_003098550.1 256374890 8324904 complement(818803..819153) 1 NC_013093.1 hypothetical protein 819153 8324904 Amir_0741 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098550.1 818803 R 446462 CDS YP_003098551.1 256374891 8324905 complement(819606..819710) 1 NC_013093.1 hypothetical protein 819710 8324905 Amir_0742 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098551.1 819606 R 446462 CDS YP_003098552.1 256374892 8324906 819816..821012 1 NC_013093.1 involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis; mannosyltransferase 821012 pimE 8324906 pimE Actinosynnema mirum DSM 43827 mannosyltransferase YP_003098552.1 819816 D 446462 CDS YP_003098553.1 256374893 8324908 complement(821250..821543) 1 NC_013093.1 PFAM: transcriptional coactivator/pterin dehydratase; KEGG: mxa:MXAN_6773 pterin-4-alpha- carbinolamine dehydratase; transcriptional coactivator/pterin dehydratase 821543 8324908 Amir_0745 Actinosynnema mirum DSM 43827 transcriptional coactivator/pterin dehydratase YP_003098553.1 821250 R 446462 CDS YP_003098554.1 256374894 8324909 821679..822713 1 NC_013093.1 TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; PFAM: extracellular solute-binding protein family 1; KEGG: cvi:CV_3164 thiamin-binding periplasmic protein; ABC transporter periplasmic protein 822713 8324909 Amir_0746 Actinosynnema mirum DSM 43827 ABC transporter periplasmic protein YP_003098554.1 821679 D 446462 CDS YP_003098555.1 256374895 8324910 822803..824446 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rfr:Rfer_3245 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 824446 8324910 Amir_0747 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098555.1 822803 D 446462 CDS YP_003098556.1 256374896 8324911 824446..825447 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bra:BRADO7092 spermidine/putrescine ABC transporter ATP-binding protein; ABC transporter 825447 8324911 Amir_0748 Actinosynnema mirum DSM 43827 ABC transporter YP_003098556.1 824446 D 446462 CDS YP_003098557.1 256374897 8324912 complement(825493..826359) 1 NC_013093.1 KEGG: aeh:Mlg_1077 ABC-type transport system involved in multi-copper enzyme maturation, permease component; hypothetical protein 826359 8324912 Amir_0749 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098557.1 825493 R 446462 CDS YP_003098558.1 256374898 8324913 complement(826356..829865) 1 NC_013093.1 KEGG: proteophosphoglycan 5; hypothetical protein 829865 8324913 Amir_0750 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098558.1 826356 R 446462 CDS YP_003098559.1 256374899 8324914 complement(829862..830890) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH0445 ABC transporter ATP-binding protein; ABC transporter 830890 8324914 Amir_0751 Actinosynnema mirum DSM 43827 ABC transporter YP_003098559.1 829862 R 446462 CDS YP_003098560.1 256374900 8324915 complement(830887..832089) 1 NC_013093.1 KEGG: pau:PA14_50860 hypothetical protein; hypothetical protein 832089 8324915 Amir_0752 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098560.1 830887 R 446462 CDS YP_003098561.1 256374901 8324916 832249..832974 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: met:M446_6140 two component transcriptional regulator; winged helix family two component transcriptional regulator 832974 8324916 Amir_0753 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003098561.1 832249 D 446462 CDS YP_003098562.1 256374902 8324917 832971..834254 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase 834254 8324917 Amir_0754 Actinosynnema mirum DSM 43827 histidine kinase YP_003098562.1 832971 D 446462 CDS YP_003098563.1 256374903 8324918 834452..835255 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: scl:sce8529 Nudix/MutT family protein; NUDIX hydrolase 835255 8324918 Amir_0755 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003098563.1 834452 D 446462 CDS YP_003098564.1 256374904 8324919 complement(835671..836636) 1 NC_013093.1 KEGG: hsm:HSM_0044 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; tryptophanyl-tRNA synthetase 836636 8324919 Amir_0756 Actinosynnema mirum DSM 43827 tryptophanyl-tRNA synthetase YP_003098564.1 835671 R 446462 CDS YP_003098565.1 256374905 8324920 836836..837138 1 NC_013093.1 PFAM: YCII-related; KEGG: bpy:Bphyt_0556 YCII-related; YCII-like protein 837138 8324920 Amir_0757 Actinosynnema mirum DSM 43827 YCII-like protein YP_003098565.1 836836 D 446462 CDS YP_003098566.1 256374906 8324921 complement(837484..837645) 1 NC_013093.1 hypothetical protein 837645 8324921 Amir_0758 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098566.1 837484 R 446462 CDS YP_003098567.1 256374907 8324922 837810..839711 1 NC_013093.1 TIGRFAM: GTP-binding protein TypA; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: aba:Acid345_4404 GTP-binding protein TypA; GTP-binding protein TypA 839711 8324922 Amir_0759 Actinosynnema mirum DSM 43827 GTP-binding protein TypA YP_003098567.1 837810 D 446462 CDS YP_003098568.1 256374908 8324923 839987..841687 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: mes:Meso_1835 extracellular solute-binding protein, family 5; family 5 extracellular solute-binding protein 841687 8324923 Amir_0760 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003098568.1 839987 D 446462 CDS YP_003098569.1 256374909 8324924 841988..843802 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: mes:Meso_1835 extracellular solute-binding protein, family 5; family 5 extracellular solute-binding protein 843802 8324924 Amir_0761 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003098569.1 841988 D 446462 CDS YP_003098570.1 256374910 8324925 843963..844961 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_1834 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 844961 8324925 Amir_0762 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098570.1 843963 D 446462 CDS YP_003098571.1 256374911 8324926 844963..845901 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_1833 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 845901 8324926 Amir_0763 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098571.1 844963 D 446462 CDS YP_003098572.1 256374912 8324927 845898..847076 1 NC_013093.1 KEGG: bcs:BCAN_B1102 oligopeptide/dipeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 847076 8324927 Amir_0764 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003098572.1 845898 D 446462 CDS YP_003098573.1 256374913 8324928 847073..848122 1 NC_013093.1 KEGG: bra:BRADO1097 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 848122 8324928 Amir_0765 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003098573.1 847073 D 446462 CDS YP_003098574.1 256374914 8324929 848250..849101 1 NC_013093.1 TIGRFAM:1D-myo-inosityl-2-acetamido-2-deoxy-alpha- D- glucopyranosidedeacetylase; PFAM: LmbE family protein; KEGG: aba:Acid345_2880 LmbE-like protein; 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranosidedeacetylase 849101 8324929 Amir_0766 Actinosynnema mirum DSM 43827 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranosidedeacetylase YP_003098574.1 848250 D 446462 CDS YP_003098575.1 256374915 8324930 849200..849580 1 NC_013093.1 hypothetical protein 849580 8324930 Amir_0767 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098575.1 849200 D 446462 CDS YP_003098576.1 256374916 8324931 849761..850825 1 NC_013093.1 KEGG: met:M446_5119 flagellar hook-length control protein; hypothetical protein 850825 8324931 Amir_0768 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098576.1 849761 D 446462 CDS YP_003098577.1 256374917 8324932 complement(850804..851637) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ccs:CCNA_02292 acetyltransferase; GCN5-like N-acetyltransferase 851637 8324932 Amir_0769 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003098577.1 850804 R 446462 CDS YP_003098578.1 256374918 8324933 851796..852122 1 NC_013093.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: vei:Veis_3502 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 852122 8324933 Amir_0770 Actinosynnema mirum DSM 43827 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_003098578.1 851796 D 446462 CDS YP_003098579.1 256374919 8324934 852119..853210 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: afw:Anae109_3944 aminotransferase class I and II; class I and II aminotransferase 853210 8324934 Amir_0771 Actinosynnema mirum DSM 43827 class I and II aminotransferase YP_003098579.1 852119 D 446462 CDS YP_003098580.1 256374920 8324935 complement(853292..854266) 1 NC_013093.1 KEGG: vch:VC2329 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase; 2,3,4, 5-tetrahydropyridine-2-carboxylateN-succinyltransferase 854266 8324935 Amir_0772 Actinosynnema mirum DSM 43827 2,3,4, 5-tetrahydropyridine-2-carboxylateN-succinyltransferase YP_003098580.1 853292 R 446462 CDS YP_003098581.1 256374921 8324936 854283..855362 1 NC_013093.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 855362 8324936 Amir_0773 Actinosynnema mirum DSM 43827 succinyl-diaminopimelate desuccinylase YP_003098581.1 854283 D 446462 CDS YP_003098582.1 256374922 8324937 855382..856149 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: hypothetical protein; hypothetical protein 856149 8324937 Amir_0774 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098582.1 855382 D 446462 CDS YP_003098583.1 256374923 8324938 856149..856691 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: mpt:Mpe_A2111 hypothetical protein; hypothetical protein 856691 8324938 Amir_0775 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098583.1 856149 D 446462 CDS YP_003098584.1 256374924 8324939 complement(856763..858316) 1 NC_013093.1 PFAM: peptidase S15; X-Pro dipeptidyl-peptidase domain protein; acetyl xylan esterase; KEGG: sml:Smlt2609 X-Pro dipeptidyl- peptidase protein; peptidase S15 858316 8324939 Amir_0776 Actinosynnema mirum DSM 43827 peptidase S15 YP_003098584.1 856763 R 446462 CDS YP_003098585.1 256374925 8324940 858410..859270 1 NC_013093.1 KEGG: ade:Adeh_1496 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; dihydropteroate synthase 859270 8324940 Amir_0777 Actinosynnema mirum DSM 43827 dihydropteroate synthase YP_003098585.1 858410 D 446462 CDS YP_003098586.1 256374926 8324941 859337..859684 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: aba:Acid345_4626 transcriptional regulator, PadR family; PadR family transcriptional regulator 859684 8324941 Amir_0778 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003098586.1 859337 D 446462 CDS YP_003098587.1 256374927 8324942 859772..860347 1 NC_013093.1 KEGG: GD17417 gene product from transcript GD17417- RA; hypothetical protein 860347 8324942 Amir_0779 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098587.1 859772 D 446462 CDS YP_003098588.1 256374928 8324943 860334..860765 1 NC_013093.1 hypothetical protein 860765 8324943 Amir_0780 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098588.1 860334 D 446462 CDS YP_003098589.1 256374929 8324944 860768..861346 1 NC_013093.1 KEGG: tmz:Tmz1t_2227 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase; DNA-3-methyladenine glycosylase I 861346 8324944 Amir_0781 Actinosynnema mirum DSM 43827 DNA-3-methyladenine glycosylase I YP_003098589.1 860768 D 446462 CDS YP_003098590.1 256374930 8324945 complement(861347..862234) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: ccs:CCNA_02424 transcriptional regulator, TetR family; TetR family transcriptional regulator 862234 8324945 Amir_0782 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098590.1 861347 R 446462 CDS YP_003098591.1 256374931 8324946 862339..863382 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bph:Bphy_2359 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 863382 8324946 Amir_0783 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003098591.1 862339 D 446462 CDS YP_003098592.1 256374932 8324947 863379..863972 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: cak:Caul_3929 TetR family transcriptional regulator; TetR family transcriptional regulator 863972 8324947 Amir_0784 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098592.1 863379 D 446462 CDS YP_003098593.1 256374933 8324948 864008..864613 1 NC_013093.1 KEGG: met:M446_0017 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 864613 8324948 Amir_0785 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098593.1 864008 D 446462 CDS YP_003098594.1 256374934 8324949 complement(864738..865520) 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: dac:Daci_0568 enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase 865520 8324949 Amir_0786 Actinosynnema mirum DSM 43827 enoyl-CoA hydratase/isomerase YP_003098594.1 864738 R 446462 CDS YP_003098595.1 256374935 8324950 complement(865668..866474) 1 NC_013093.1 PFAM: PaaX domain protein domain; PaaX domain protein; KEGG: bha:BH0194 repressor in the phenylacetic acid catabolic pathway; PaaX family transcriptional regulator 866474 8324950 Amir_0787 Actinosynnema mirum DSM 43827 PaaX family transcriptional regulator YP_003098595.1 865668 R 446462 CDS YP_003098596.1 256374936 8324951 866738..866905 1 NC_013093.1 hypothetical protein 866905 8324951 Amir_0788 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098596.1 866738 D 446462 CDS YP_003098597.1 256374937 8324952 867012..868379 1 NC_013093.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: rce:RC1_1566 leucyl aminopeptidase PepA; Leucyl aminopeptidase 868379 8324952 Amir_0789 Actinosynnema mirum DSM 43827 Leucyl aminopeptidase YP_003098597.1 867012 D 446462 CDS YP_003098598.1 256374938 8324953 complement(868404..869489) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bsu:BSU40670 hypothetical protein; LysR family transcriptional regulator 869489 8324953 Amir_0790 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003098598.1 868404 R 446462 CDS YP_003098599.1 256374939 8324954 869516..870820 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: acr:Acry_1491 major facilitator transporter; major facilitator superfamily protein 870820 8324954 Amir_0791 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098599.1 869516 D 446462 CDS YP_003098600.1 256374940 8324956 complement(872197..873384) 1 NC_013093.1 TIGRFAM: glycogen synthase; PFAM: glycosyl transferase group 1; KEGG: bmj:BMULJ_06045 glycosyltransferase; glycogen synthase 873384 8324956 Amir_0793 Actinosynnema mirum DSM 43827 glycogen synthase YP_003098600.1 872197 R 446462 CDS YP_003098601.1 256374941 8324957 873475..874695 1 NC_013093.1 TIGRFAM: glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; KEGG: mxa:MXAN_1524 glucose-1-phosphate adenylyltransferase; glucose-1-phosphate adenylyltransferase 874695 8324957 Amir_0794 Actinosynnema mirum DSM 43827 glucose-1-phosphate adenylyltransferase YP_003098601.1 873475 D 446462 CDS YP_003098602.1 256374942 8324958 875108..875692 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: sus:Acid_0793 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 875692 8324958 Amir_0795 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003098602.1 875108 D 446462 CDS YP_003098603.1 256374943 8324959 875689..876336 1 NC_013093.1 KEGG: similar to sperm associated antigen 8 isoform 2; transmembrane anti-sigma factor 876336 8324959 Amir_0796 Actinosynnema mirum DSM 43827 transmembrane anti-sigma factor YP_003098603.1 875689 D 446462 CDS YP_003098604.1 256374944 8324960 876404..877942 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: rfr:Rfer_2959 peptidase S1 and S6, chymotrypsin/Hap; peptidase S1 and S6 chymotrypsin/Hap 877942 8324960 Amir_0797 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003098604.1 876404 D 446462 CDS YP_003098605.1 256374945 8324961 878054..878443 1 NC_013093.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 878443 8324961 Amir_0798 Actinosynnema mirum DSM 43827 sec-independent translocase YP_003098605.1 878054 D 446462 CDS YP_003098606.1 256374946 8324962 complement(878625..879770) 1 NC_013093.1 PFAM: protein of unknown function DUF59; KEGG: bcr:BCAH187_A3588 mrp protein; hypothetical protein 879770 8324962 Amir_0799 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098606.1 878625 R 446462 CDS YP_003098607.1 256374947 8324963 879919..880422 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: pst:PSPTO_3861 MarR family transcriptional regulator; MarR family transcriptional regulator 880422 8324963 Amir_0800 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003098607.1 879919 D 446462 CDS YP_003098608.1 256374948 8324964 complement(880438..881028) 1 NC_013093.1 PFAM: protein of unknown function DUF1003; KEGG: ppf:Pput_1917 hypothetical protein; hypothetical protein 881028 8324964 Amir_0801 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098608.1 880438 R 446462 CDS YP_003098609.1 256374949 8324965 complement(881021..882271) 1 NC_013093.1 PFAM: MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: gur:Gura_2041 MgtE intracellular region; MgtE intracellular region 882271 8324965 Amir_0802 Actinosynnema mirum DSM 43827 MgtE intracellular region YP_003098609.1 881021 R 446462 CDS YP_003098610.1 256374950 8324966 complement(882299..883156) 1 NC_013093.1 PFAM: aminoglycoside/hydroxyurea antibiotic resistance kinase; KEGG: pap:PSPA7_3432 streptomycin 3''-kinase (streptomycin 3''-phosphotransferase) (SPH); aminoglycoside/hydroxyurea antibiotic resistance kinase 883156 8324966 Amir_0803 Actinosynnema mirum DSM 43827 aminoglycoside/hydroxyurea antibiotic resistance kinase YP_003098610.1 882299 R 446462 CDS YP_003098611.1 256374951 8324967 complement(883153..883473) 1 NC_013093.1 hypothetical protein 883473 8324967 Amir_0804 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098611.1 883153 R 446462 CDS YP_003098612.1 256374952 8324968 883598..884557 1 NC_013093.1 PFAM: HpcH/HpaI aldolase; KEGG: sil:SPO1565 citrate lyase; Citrate (pro-3S)-lyase 884557 8324968 Amir_0805 Actinosynnema mirum DSM 43827 Citrate (pro-3S)-lyase YP_003098612.1 883598 D 446462 CDS YP_003098613.1 256374953 8324969 884815..885354 1 NC_013093.1 KEGG: har:HEAR2359 permease; hypothetical protein 885354 8324969 Amir_0806 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098613.1 884815 D 446462 CDS YP_003098614.1 256374954 8324970 885780..887042 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: noc:Noc_0282 extracellular solute-binding protein; family 1 extracellular solute-binding protein 887042 8324970 Amir_0807 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003098614.1 885780 D 446462 CDS YP_003098615.1 256374955 8324971 887039..887995 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: noc:Noc_0281 ABC transporter, inner membrane subunit; ABC transporter inner membrane protein 887995 8324971 Amir_0808 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098615.1 887039 D 446462 CDS YP_003098616.1 256374956 8324972 887995..888840 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: noc:Noc_0280 ABC transporter, inner membrane subunit; ABC transporter inner membrane protein 888840 8324972 Amir_0809 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098616.1 887995 D 446462 CDS YP_003098617.1 256374957 8324973 888841..890031 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: noc:Noc_0279 ABC transporter, ATPase subunit; ABC transporter 890031 8324973 Amir_0810 Actinosynnema mirum DSM 43827 ABC transporter YP_003098617.1 888841 D 446462 CDS YP_003098618.1 256374958 8324974 890368..891258 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rpb:RPB_3589 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 891258 8324974 Amir_0811 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003098618.1 890368 D 446462 CDS YP_003098619.1 256374959 8324975 891313..892278 1 NC_013093.1 hypothetical protein 892278 8324975 Amir_0812 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098619.1 891313 D 446462 CDS YP_003098620.1 256374960 8324976 892336..892941 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: bmj:BMULJ_03145 PadR-like family transcriptional regulator; PadR family transcriptional regulator 892941 8324976 Amir_0813 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003098620.1 892336 D 446462 CDS YP_003098621.1 256374961 8324977 893043..894131 1 NC_013093.1 KEGG: mno:Mnod_7454 hypothetical protein; hypothetical protein 894131 8324977 Amir_0814 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098621.1 893043 D 446462 CDS YP_003098622.1 256374962 8324978 complement(894210..894305) 1 NC_013093.1 hypothetical protein 894305 8324978 Amir_0815 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098622.1 894210 R 446462 CDS YP_003098623.1 256374963 8324979 complement(894345..895448) 1 NC_013093.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: reh:H16_A0087 Mg2+ and Co2+ transporter; magnesium and cobalt transport protein CorA 895448 8324979 Amir_0816 Actinosynnema mirum DSM 43827 magnesium and cobalt transport protein CorA YP_003098623.1 894345 R 446462 CDS YP_003098624.1 256374964 8324980 895981..897048 1 NC_013093.1 KEGG: sil:SPO0916 hypothetical protein; hypothetical protein 897048 8324980 Amir_0817 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098624.1 895981 D 446462 CDS YP_003098625.1 256374965 8324981 897890..898048 1 NC_013093.1 hypothetical protein 898048 8324981 Amir_0818 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098625.1 897890 D 446462 CDS YP_003098626.1 256374966 8324982 898098..898658 1 NC_013093.1 PFAM: membrane-flanked domain; KEGG: acr:Acry_0579 membrane-flanked domain- containing protein; membrane-flanked domain-containing protein 898658 8324982 Amir_0819 Actinosynnema mirum DSM 43827 membrane-flanked domain-containing protein YP_003098626.1 898098 D 446462 CDS YP_003098627.1 256374967 8324983 898676..899533 1 NC_013093.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: mxa:MXAN_2739 hypothetical protein; PHP domain-containing protein 899533 8324983 Amir_0820 Actinosynnema mirum DSM 43827 PHP domain-containing protein YP_003098627.1 898676 D 446462 CDS YP_003098628.1 256374968 8324984 899938..900777 1 NC_013093.1 KEGG: mxa:MXAN_1877 hypothetical protein; hypothetical protein 900777 8324984 Amir_0821 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098628.1 899938 D 446462 CDS YP_003098629.1 256374969 8324985 complement(901612..902448) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: met:M446_0531 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 902448 8324985 Amir_0822 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003098629.1 901612 R 446462 CDS YP_003098630.1 256374970 8324986 complement(902513..903991) 1 NC_013093.1 KEGG: dno:DNO_0690 hypothetical protein; hypothetical protein 903991 8324986 Amir_0823 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098630.1 902513 R 446462 CDS YP_003098631.1 256374971 8324987 complement(904032..905861) 1 NC_013093.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: rle:RL3597 DEAD box ATP-dependent RNA helicase protein; DEAD/DEAH box helicase domain-containing protein 905861 8324987 Amir_0824 Actinosynnema mirum DSM 43827 DEAD/DEAH box helicase domain-containing protein YP_003098631.1 904032 R 446462 CDS YP_003098632.1 256374972 8324988 906189..906866 1 NC_013093.1 hypothetical protein 906866 8324988 Amir_0825 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098632.1 906189 D 446462 CDS YP_003098633.1 256374973 8324989 906909..907136 1 NC_013093.1 hypothetical protein 907136 8324989 Amir_0826 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098633.1 906909 D 446462 CDS YP_003098634.1 256374974 8324990 complement(907308..907700) 1 NC_013093.1 hypothetical protein 907700 8324990 Amir_0827 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098634.1 907308 R 446462 CDS YP_003098635.1 256374975 8324991 complement(907697..908524) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mxa:MXAN_5545 transcriptional regulator, TetR family; TetR family transcriptional regulator 908524 8324991 Amir_0828 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098635.1 907697 R 446462 CDS YP_003098636.1 256374976 8324992 908586..909485 1 NC_013093.1 KEGG: afr:AFE_2323 hypothetical protein; hypothetical protein 909485 8324992 Amir_0829 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098636.1 908586 D 446462 CDS YP_003098637.1 256374977 8324993 complement(909527..910171) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mxa:MXAN_5545 transcriptional regulator, TetR family; TetR family transcriptional regulator 910171 8324993 Amir_0830 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098637.1 909527 R 446462 CDS YP_003098638.1 256374978 8324994 910283..911317 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: rsp:RSP_1258 hydrolase; alpha/beta hydrolase fold protein 911317 8324994 Amir_0831 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003098638.1 910283 D 446462 CDS YP_003098639.1 256374979 8324995 911388..912422 1 NC_013093.1 hypothetical protein 912422 8324995 Amir_0832 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098639.1 911388 D 446462 CDS YP_003098640.1 256374980 8324996 912541..913713 1 NC_013093.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; molybdopterin biosynthesis-like protein MoeZ 913713 8324996 Amir_0833 Actinosynnema mirum DSM 43827 molybdopterin biosynthesis-like protein MoeZ YP_003098640.1 912541 D 446462 CDS YP_003098641.1 256374981 8324997 914297..915115 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: rle:RL1223 hypothetical protein; aminoglycoside phosphotransferase 915115 8324997 Amir_0834 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003098641.1 914297 D 446462 CDS YP_003098642.1 256374982 8324998 915248..917281 1 NC_013093.1 PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: msl:Msil_3772 molybdopterin oxidoreductase; molybdopterin oxidoreductase 917281 8324998 Amir_0835 Actinosynnema mirum DSM 43827 molybdopterin oxidoreductase YP_003098642.1 915248 D 446462 CDS YP_003098643.1 256374983 8324999 917496..918983 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: scl:sce3488 nitrite reductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 918983 8324999 Amir_0836 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003098643.1 917496 D 446462 CDS YP_003098644.1 256374984 8325000 919254..920606 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr2806 nitrite extrusion protein; major facilitator superfamily protein 920606 8325000 Amir_0837 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098644.1 919254 D 446462 CDS YP_003098645.1 256374985 8325001 920982..923486 1 NC_013093.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: bam:Bamb_3936 nitrite reductase (NAD(P)H), large subunit; nitrite reductase (NAD(P)H), large subunit 923486 8325001 Amir_0838 Actinosynnema mirum DSM 43827 nitrite reductase (NAD(P)H), large subunit YP_003098645.1 920982 D 446462 CDS YP_003098646.1 256374986 8325002 923501..923893 1 NC_013093.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: mfa:Mfla_0318 nitrite reductase (NAD(P)H) large subunit, NirD; nitrite reductase (NAD(P)H), small subunit 923893 8325002 Amir_0839 Actinosynnema mirum DSM 43827 nitrite reductase (NAD(P)H), small subunit YP_003098646.1 923501 D 446462 CDS YP_003098647.1 256374987 8325003 923932..925077 1 NC_013093.1 PFAM: uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: scl:sce6449 transcriptional regulator; uroporphyrinogen III synthase HEM4 925077 8325003 Amir_0840 Actinosynnema mirum DSM 43827 uroporphyrinogen III synthase HEM4 YP_003098647.1 923932 D 446462 CDS YP_003098648.1 256374988 8325004 925074..925832 1 NC_013093.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 transmembrane protein; cobalamin (vitamin B12) biosynthesis CbiX protein 925832 8325004 Amir_0841 Actinosynnema mirum DSM 43827 cobalamin (vitamin B12) biosynthesis CbiX protein YP_003098648.1 925074 D 446462 CDS YP_003098649.1 256374989 8325005 complement(925944..926273) 1 NC_013093.1 hypothetical protein 926273 8325005 Amir_0842 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098649.1 925944 R 446462 CDS YP_003098650.1 256374990 8325006 complement(926722..927141) 1 NC_013093.1 hypothetical protein 927141 8325006 Amir_0843 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098650.1 926722 R 446462 CDS YP_003098651.1 256374991 8325007 927294..927980 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pst:PSPTO_1307 DNA-binding heavy metal response regulator; winged helix family two component transcriptional regulator 927980 8325007 Amir_0844 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003098651.1 927294 D 446462 CDS YP_003098652.1 256374992 8325008 927977..929347 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gsu:GSU0452 sensor histidine kinase; histidine kinase 929347 8325008 Amir_0845 Actinosynnema mirum DSM 43827 histidine kinase YP_003098652.1 927977 D 446462 CDS YP_003098653.1 256374993 8325009 complement(929344..929691) 1 NC_013093.1 hypothetical protein 929691 8325009 Amir_0846 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098653.1 929344 R 446462 CDS YP_003098654.1 256374994 8325010 complement(929748..930827) 1 NC_013093.1 PFAM: TrkA-N domain protein; Ion transport 2 domain protein; KEGG: bpy:Bphyt_4906 TrkA-N domain protein; TrkA-N domain-containing protein 930827 8325010 Amir_0847 Actinosynnema mirum DSM 43827 TrkA-N domain-containing protein YP_003098654.1 929748 R 446462 CDS YP_003098655.1 256374995 8325011 complement(930827..932266) 1 NC_013093.1 PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: mgm:Mmc1_1548 peptidase M20; peptidase M20 932266 8325011 Amir_0848 Actinosynnema mirum DSM 43827 peptidase M20 YP_003098655.1 930827 R 446462 CDS YP_003098656.1 256374996 8325012 932326..932709 1 NC_013093.1 KEGG: mxa:MXAN_6481 hypothetical protein; hypothetical protein 932709 8325012 Amir_0849 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098656.1 932326 D 446462 CDS YP_003098657.1 256374997 8325013 932790..933335 1 NC_013093.1 hypothetical protein 933335 8325013 Amir_0850 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098657.1 932790 D 446462 CDS YP_003098658.1 256374998 8325014 complement(933357..937406) 1 NC_013093.1 PFAM: UvrD/REP helicase; KEGG: xau:Xaut_0776 UvrD/REP helicase; UvrD/REP helicase 937406 8325014 Amir_0851 Actinosynnema mirum DSM 43827 UvrD/REP helicase YP_003098658.1 933357 R 446462 CDS YP_003098659.1 256374999 8325015 complement(937928..941080) 1 NC_013093.1 PFAM: UvrD/REP helicase; KEGG: ank:AnaeK_0104 UvrD/REP helicase; UvrD/REP helicase 941080 8325015 Amir_0852 Actinosynnema mirum DSM 43827 UvrD/REP helicase YP_003098659.1 937928 R 446462 CDS YP_003098660.1 256375000 8325016 941213..941548 1 NC_013093.1 PFAM: methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; KEGG: aci:ACIAD2864 methyltransferase; methylated-DNA-(protein)-cysteine S- methyltransferase DNA binding 941548 8325016 Amir_0853 Actinosynnema mirum DSM 43827 methylated-DNA-(protein)-cysteine S- methyltransferase DNA binding YP_003098660.1 941213 D 446462 CDS YP_003098661.1 256375001 8325017 complement(941628..941996) 1 NC_013093.1 SMART: hypothetical protein; KEGG: oca:OCAR_7425 TPR repeat protein; hypothetical protein 941996 8325017 Amir_0854 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098661.1 941628 R 446462 CDS YP_003098662.1 256375002 8325018 complement(942082..942825) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mll2196 short chain oxidoreductase; short-chain dehydrogenase/reductase SDR 942825 8325018 Amir_0855 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003098662.1 942082 R 446462 CDS YP_003098663.1 256375003 8325019 942907..943812 1 NC_013093.1 PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: scl:sce1423 LysR family transcriptional regulator; LysR family transcriptional regulator 943812 8325019 Amir_0856 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003098663.1 942907 D 446462 CDS YP_003098664.1 256375004 8325020 complement(943891..944799) 1 NC_013093.1 PFAM: protein of unknown function zinc metallopeptidase KEGG: atc:AGR_C_3948 conserved hypothetical protein PA4717; hypothetical protein 944799 8325020 Amir_0857 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098664.1 943891 R 446462 CDS YP_003098665.1 256375005 8325021 complement(944829..945872) 1 NC_013093.1 PFAM: protein of unknown function zinc metallopeptidase KEGG: dno:DNO_0928 hypothetical protein; hypothetical protein 945872 8325021 Amir_0858 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098665.1 944829 R 446462 CDS YP_003098666.1 256375006 8325022 946230..947879 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 947879 8325022 Amir_0859 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098666.1 946230 D 446462 CDS YP_003098667.1 256375007 8325023 complement(948072..948344) 1 NC_013093.1 PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; KEGG: pen:PSEEN1871 DNA-binding protein HU-beta; histone family protein DNA-binding protein 948344 8325023 Amir_0860 Actinosynnema mirum DSM 43827 histone family protein DNA-binding protein YP_003098667.1 948072 R 446462 CDS YP_003098668.1 256375008 8325024 complement(948618..949157) 1 NC_013093.1 PFAM: protein of unknown function DUF1470; KEGG: bcm:Bcenmc03_4753 hypothetical protein; hypothetical protein 949157 8325024 Amir_0861 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098668.1 948618 R 446462 CDS YP_003098669.1 256375009 8325025 949248..950123 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: msl:Msil_2561 alpha/beta hydrolase fold protein; alpha/beta hydrolase fold protein 950123 8325025 Amir_0862 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003098669.1 949248 D 446462 CDS YP_003098670.1 256375010 8325026 950249..951535 1 NC_013093.1 PFAM: peptidase M16 domain protein; KEGG: afw:Anae109_0081 peptidase M16 domain- containing protein; peptidase M16 domain-containing protein 951535 8325026 Amir_0863 Actinosynnema mirum DSM 43827 peptidase M16 domain-containing protein YP_003098670.1 950249 D 446462 CDS YP_003098671.1 256375011 8325027 951532..952920 1 NC_013093.1 PFAM: peptidase M16 domain protein; KEGG: mxa:MXAN_1624 peptidase, M16 (pitrilysin) family; peptidase M16 domain-containing protein 952920 8325027 Amir_0864 Actinosynnema mirum DSM 43827 peptidase M16 domain-containing protein YP_003098671.1 951532 D 446462 CDS YP_003098672.1 256375012 8325028 952917..953876 1 NC_013093.1 PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: xcv:XCV0537 NUDIX hydrolase family protein; NUDIX hydrolase 953876 8325028 Amir_0865 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003098672.1 952917 D 446462 CDS YP_003098673.1 256375013 8325029 954106..955323 1 NC_013093.1 PFAM: ROK family protein; KEGG: bha:BH1094 transcriptional repressor of the xylose operon; ROK family protein 955323 8325029 Amir_0866 Actinosynnema mirum DSM 43827 ROK family protein YP_003098673.1 954106 D 446462 CDS YP_003098674.1 256375014 8325030 complement(955320..955928) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce8247 TetR family transcriptional regulator; TetR family transcriptional regulator 955928 8325030 Amir_0867 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098674.1 955320 R 446462 CDS YP_003098675.1 256375015 8325031 955999..957054 1 NC_013093.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sus:Acid_6576 amidohydrolase; amidohydrolase 957054 8325031 Amir_0868 Actinosynnema mirum DSM 43827 amidohydrolase YP_003098675.1 955999 D 446462 CDS YP_003098676.1 256375016 8325032 complement(957113..961177) 1 NC_013093.1 KEGG: scl:sce2125 hypothetical protein; hypothetical protein 961177 8325032 Amir_0869 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098676.1 957113 R 446462 CDS YP_003098677.1 256375017 8325033 complement(961174..962343) 1 NC_013093.1 KEGG: afw:Anae109_1073 hypothetical protein; hypothetical protein 962343 8325033 Amir_0870 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098677.1 961174 R 446462 CDS YP_003098678.1 256375018 8325034 complement(962346..963824) 1 NC_013093.1 KEGG: scl:sce2127 hypothetical protein; hypothetical protein 963824 8325034 Amir_0871 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098678.1 962346 R 446462 CDS YP_003098679.1 256375019 8325035 964072..965019 1 NC_013093.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; KEGG: glo:Glov_3553 cobalamin biosynthesis protein CobD; cobalamin biosynthesis protein CobD 965019 8325035 Amir_0872 Actinosynnema mirum DSM 43827 cobalamin biosynthesis protein CobD YP_003098679.1 964072 D 446462 CDS YP_003098680.1 256375020 8325036 complement(965106..965984) 1 NC_013093.1 KEGG: bbt:BBta_2034 SURF1 family protein; SURF1 family protein 965984 8325036 Amir_0873 Actinosynnema mirum DSM 43827 SURF1 family protein YP_003098680.1 965106 R 446462 CDS YP_003098681.1 256375021 8325037 complement(966144..967013) 1 NC_013093.1 PFAM: fructosamine kinase; aminoglycoside phosphotransferase; KEGG: hch:HCH_00321 fructosamine-3-kinase; fructosamine kinase 967013 8325037 Amir_0874 Actinosynnema mirum DSM 43827 fructosamine kinase YP_003098681.1 966144 R 446462 CDS YP_003098682.1 256375022 8325038 complement(967010..967468) 1 NC_013093.1 PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; KEGG: rru:Rru_A3646 protein tyrosine phosphatase; protein tyrosine phosphatase 967468 8325038 Amir_0875 Actinosynnema mirum DSM 43827 protein tyrosine phosphatase YP_003098682.1 967010 R 446462 CDS YP_003098683.1 256375023 8325039 967621..968277 1 NC_013093.1 SMART: HNH nuclease; KEGG: ank:AnaeK_4158 HNH nuclease; HNH nuclease 968277 8325039 Amir_0876 Actinosynnema mirum DSM 43827 HNH nuclease YP_003098683.1 967621 D 446462 CDS YP_003098684.1 256375024 8325040 968490..968609 1 NC_013093.1 hypothetical protein 968609 8325040 Amir_0877 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098684.1 968490 D 446462 CDS YP_003098685.1 256375025 8325041 968695..969738 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: cko:CKO_02518 threonine-phosphate decarboxylase; class I and II aminotransferase 969738 8325041 Amir_0878 Actinosynnema mirum DSM 43827 class I and II aminotransferase YP_003098685.1 968695 D 446462 CDS YP_003098686.1 256375026 8325042 969735..970877 1 NC_013093.1 PFAM: protein of unknown function DUF34; KEGG: pca:Pcar_2677 hypothetical protein; hypothetical protein 970877 8325042 Amir_0879 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098686.1 969735 D 446462 CDS YP_003098687.1 256375027 8325043 970879..971616 1 NC_013093.1 PFAM: protein of unknown function DUF164; KEGG: wsu:WS2117 hypothetical protein; hypothetical protein 971616 8325043 Amir_0880 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098687.1 970879 D 446462 CDS YP_003098688.1 256375028 8325044 971613..972788 1 NC_013093.1 PFAM: phosphoglycerate mutase; ribonuclease H; KEGG: mxa:MXAN_5728 ribonuclease H; phosphoglycerate mutase 972788 8325044 Amir_0881 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003098688.1 971613 D 446462 CDS YP_003098689.1 256375029 8325045 complement(973824..974369) 1 NC_013093.1 PFAM: NADPH-dependent FMN reductase; KEGG: cti:RALTA_A1785 NAD(P)H-dependent FMN reductase, sulfate starvation-induced protein; NADPH-dependent FMN reductase 974369 8325045 Amir_0882 Actinosynnema mirum DSM 43827 NADPH-dependent FMN reductase YP_003098689.1 973824 R 446462 CDS YP_003098690.1 256375030 8325047 complement(975092..975562) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 975562 8325047 Amir_0883 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098690.1 975092 R 446462 CDS YP_003098691.1 256375031 8325048 975952..976227 1 NC_013093.1 hypothetical protein 976227 8325048 Amir_0884 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098691.1 975952 D 446462 CDS YP_003098692.1 256375032 8325049 976232..976729 1 NC_013093.1 KEGG: GJ12100 gene product from transcript GJ12100- RA; hypothetical protein 976729 8325049 Amir_0885 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098692.1 976232 D 446462 CDS YP_003098693.1 256375033 8325050 976710..979577 1 NC_013093.1 KEGG: bcr:BCAH187_E0044 hypothetical protein; hypothetical protein 979577 8325050 Amir_0886 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098693.1 976710 D 446462 CDS YP_003098694.1 256375034 8325051 979574..981517 1 NC_013093.1 KEGG: ajs:Ajs_4066 single-strand binding protein; hypothetical protein 981517 8325051 Amir_0887 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098694.1 979574 D 446462 CDS YP_003098695.1 256375035 8325052 981517..982155 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 982155 8325052 Amir_0888 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098695.1 981517 D 446462 CDS YP_003098696.1 256375036 8325053 982157..983170 1 NC_013093.1 PFAM: NLP/P60 protein; KEGG: gme:Gmet_2365 NLP/P60:sporulation-related protein; NLP/P60 protein 983170 8325053 Amir_0889 Actinosynnema mirum DSM 43827 NLP/P60 protein YP_003098696.1 982157 D 446462 CDS YP_003098697.1 256375037 8325054 983271..983993 1 NC_013093.1 KEGG: scl:sce1554 prolipoprotein diacylglyceryl transferase; hypothetical protein 983993 8325054 Amir_0890 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098697.1 983271 D 446462 CDS YP_003098698.1 256375038 8325055 984139..984333 1 NC_013093.1 hypothetical protein 984333 8325055 Amir_0891 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098698.1 984139 D 446462 CDS YP_003098699.1 256375039 8325056 984474..985142 1 NC_013093.1 TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; Semialdehyde dehydrogenase NAD - binding; 6- phosphogluconate dehydrogenase NAD-binding; KEGG: oca:OCAR_5001 NADPH-dependent f420 reductase; NADPH-dependent F420 reductase 985142 8325056 Amir_0892 Actinosynnema mirum DSM 43827 NADPH-dependent F420 reductase YP_003098699.1 984474 D 446462 CDS YP_003098700.1 256375040 8325057 985142..985897 1 NC_013093.1 KEGG: scl:sce7051 periplasmic substrate- binding protein; periplasmic substrate-binding protein 985897 8325057 Amir_0893 Actinosynnema mirum DSM 43827 periplasmic substrate-binding protein YP_003098700.1 985142 D 446462 CDS YP_003098701.1 256375041 8325058 complement(985902..986837) 1 NC_013093.1 KEGG: bte:BTH_II2193 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; proline iminopeptidase 986837 8325058 Amir_0894 Actinosynnema mirum DSM 43827 proline iminopeptidase YP_003098701.1 985902 R 446462 CDS YP_003098702.1 256375042 8325059 986940..988310 1 NC_013093.1 SMART: LamG domain protein jellyroll fold domain protein; KEGG: GK16139 gene product from transcript GK16139- RA; LamG domain-containing protein 988310 8325059 Amir_0895 Actinosynnema mirum DSM 43827 LamG domain-containing protein YP_003098702.1 986940 D 446462 CDS YP_003098703.1 256375043 8325060 complement(988353..989105) 1 NC_013093.1 SMART: ATPase AAA; KEGG: rme:Rmet_4896 SMC protein-like protein; ATPase AAA 989105 8325060 Amir_0896 Actinosynnema mirum DSM 43827 ATPase AAA YP_003098703.1 988353 R 446462 CDS YP_003098704.1 256375044 8325062 complement(989737..990567) 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 990567 8325062 Amir_0898 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003098704.1 989737 R 446462 CDS YP_003098705.1 256375045 8325063 complement(990578..991321) 1 NC_013093.1 SMART: ATPase AAA; KEGG: rme:Rmet_4896 SMC protein-like protein; ATPase AAA 991321 8325063 Amir_0899 Actinosynnema mirum DSM 43827 ATPase AAA YP_003098705.1 990578 R 446462 CDS YP_003098706.1 256375046 8325064 complement(991333..992211) 1 NC_013093.1 PFAM: Radical SAM domain protein; KEGG: rpd:RPD_4322 radical SAM family protein; Radical SAM domain-containing protein 992211 8325064 Amir_0900 Actinosynnema mirum DSM 43827 Radical SAM domain-containing protein YP_003098706.1 991333 R 446462 CDS YP_003098707.1 256375047 8325065 complement(992208..992489) 1 NC_013093.1 hypothetical protein 992489 8325065 Amir_0901 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098707.1 992208 R 446462 CDS YP_003098708.1 256375048 8325066 992673..993551 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 993551 8325066 Amir_0902 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003098708.1 992673 D 446462 CDS YP_003098709.1 256375049 8325067 993548..993742 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 993742 8325067 Amir_0903 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098709.1 993548 D 446462 CDS YP_003098710.1 256375050 8325068 complement(993815..994678) 1 NC_013093.1 KEGG: glo:Glov_0957 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: ketopantoate hydroxymethyltransferase; 3-methyl-2-oxobutanoatehydroxymethyltransferase 994678 8325068 Amir_0904 Actinosynnema mirum DSM 43827 3-methyl-2-oxobutanoatehydroxymethyltransferase YP_003098710.1 993815 R 446462 CDS YP_003098711.1 256375051 8325069 complement(994858..995433) 1 NC_013093.1 KEGG: bmj:BMULJ_04515 predicted hydrolase or acyltransferase; hypothetical protein 995433 8325069 Amir_0905 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098711.1 994858 R 446462 CDS YP_003098712.1 256375052 8325070 995843..999127 1 NC_013093.1 catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 999127 lysS 8325070 lysS Actinosynnema mirum DSM 43827 lysyl-tRNA synthetase YP_003098712.1 995843 D 446462 CDS YP_003098713.1 256375053 8325071 complement(999230..1000795) 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: spe:Spro_2416 TAP domain-containing protein; TAP domain-containing protein 1000795 8325071 Amir_0907 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003098713.1 999230 R 446462 CDS YP_003098714.1 256375054 8325072 1000882..1002597 1 NC_013093.1 KEGG: csa:Csal_0495 NH(3)-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; NAD+ synthetase 1002597 8325072 Amir_0908 Actinosynnema mirum DSM 43827 NAD+ synthetase YP_003098714.1 1000882 D 446462 CDS YP_003098715.1 256375055 8325073 1002841..1004184 1 NC_013093.1 PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase; glutamine synthetase 1004184 8325073 Amir_0909 Actinosynnema mirum DSM 43827 glutamine synthetase YP_003098715.1 1002841 D 446462 CDS YP_003098716.1 256375056 8325074 1004181..1008275 1 NC_013093.1 TIGRFAM: methyltransferase FkbM family; KEGG: pzu:PHZ_c0476 hypothetical protein; methyltransferase 1008275 8325074 Amir_0910 Actinosynnema mirum DSM 43827 methyltransferase YP_003098716.1 1004181 D 446462 CDS YP_003098717.1 256375057 8325077 1013634..1014770 1 NC_013093.1 PFAM: phosphate transporter; KEGG: glo:Glov_0587 phosphate transporter; phosphate transporter 1014770 8325077 Amir_0911 Actinosynnema mirum DSM 43827 phosphate transporter YP_003098717.1 1013634 D 446462 CDS YP_003098718.1 256375058 8325078 1014767..1014991 1 NC_013093.1 hypothetical protein 1014991 8325078 Amir_0912 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098718.1 1014767 D 446462 CDS YP_003098719.1 256375059 8325079 1015032..1017968 1 NC_013093.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1017968 8325079 Amir_0913 Actinosynnema mirum DSM 43827 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_003098719.1 1015032 D 446462 CDS YP_003098720.1 256375060 8325080 complement(1018102..1018332) 1 NC_013093.1 hypothetical protein 1018332 8325080 Amir_0914 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098720.1 1018102 R 446462 CDS YP_003098721.1 256375061 8325081 1018522..1019133 1 NC_013093.1 KEGG: sml:Smlt3524 autotransporter subtilisin-like protease; hypothetical protein 1019133 8325081 Amir_0915 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098721.1 1018522 D 446462 CDS YP_003098722.1 256375062 8325082 complement(1019723..1020433) 1 NC_013093.1 PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: aha:AHA_2241 HAD family hydrolase; Haloacid dehalogenase domain-containing protein hydrolase 1020433 8325082 Amir_0916 Actinosynnema mirum DSM 43827 Haloacid dehalogenase domain-containing protein hydrolase YP_003098722.1 1019723 R 446462 CDS YP_003098723.1 256375063 8325083 complement(1020430..1021272) 1 NC_013093.1 PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: yen:YE1303 hypothetical protein; GntR family transcriptional regulator 1021272 8325083 Amir_0917 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003098723.1 1020430 R 446462 CDS YP_003098724.1 256375064 8325084 1021550..1021999 1 NC_013093.1 hypothetical protein 1021999 8325084 Amir_0918 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098724.1 1021550 D 446462 CDS YP_003098725.1 256375065 8325085 1022001..1022285 1 NC_013093.1 hypothetical protein 1022285 8325085 Amir_0919 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098725.1 1022001 D 446462 CDS YP_003098726.1 256375066 8325086 1022282..1022557 1 NC_013093.1 hypothetical protein 1022557 8325086 Amir_0920 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098726.1 1022282 D 446462 CDS YP_003098727.1 256375067 8325087 1022862..1024313 1 NC_013093.1 KEGG: pha:PSHAb0091 cell divisionFtsK/SpoIIIE domain-containing protein; DNA segregation ATPase FtsK/SpoIIIE-like protein 1024313 8325087 Amir_0921 Actinosynnema mirum DSM 43827 DNA segregation ATPase FtsK/SpoIIIE-like protein YP_003098727.1 1022862 D 446462 CDS YP_003098728.1 256375068 8325088 1024310..1025893 1 NC_013093.1 hypothetical protein 1025893 8325088 Amir_0922 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098728.1 1024310 D 446462 CDS YP_003098729.1 256375069 8325089 1025910..1026098 1 NC_013093.1 hypothetical protein 1026098 8325089 Amir_0923 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098729.1 1025910 D 446462 CDS YP_003098730.1 256375070 8325090 1026134..1027333 1 NC_013093.1 PFAM: integrase family protein; KEGG: bcb:BCB4264_A2589 DNA integration/recombination/invertion protein; integrase family protein 1027333 8325090 Amir_0924 Actinosynnema mirum DSM 43827 integrase family protein YP_003098730.1 1026134 D 446462 CDS YP_003098731.1 256375071 8325091 complement(1027480..1028904) 1 NC_013093.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: gur:Gura_2228 glutamine synthetase, type I; glutamine synthetase 1028904 8325091 Amir_0925 Actinosynnema mirum DSM 43827 glutamine synthetase YP_003098731.1 1027480 R 446462 CDS YP_003098732.1 256375072 8325092 1029103..1029576 1 NC_013093.1 PFAM: hypothetical protein; KEGG: shl:Shal_2580 RDD domain-containing protein; hypothetical protein 1029576 8325092 Amir_0926 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098732.1 1029103 D 446462 CDS YP_003098733.1 256375073 8325093 complement(1029691..1030419) 1 NC_013093.1 hypothetical protein 1030419 8325093 Amir_0927 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098733.1 1029691 R 446462 CDS YP_003098734.1 256375074 8325094 1030491..1033121 1 NC_013093.1 PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; KEGG: bam:Bamb_1322 UvrD/REP helicase; UvrD/REP helicase 1033121 8325094 Amir_0928 Actinosynnema mirum DSM 43827 UvrD/REP helicase YP_003098734.1 1030491 D 446462 CDS YP_003098735.1 256375075 8325095 1033675..1034094 1 NC_013093.1 PFAM: transcription factor WhiB; HMG-I and HMG-Y DNA-binding domain protein; transcription factor WhiB 1034094 8325095 Amir_0929 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003098735.1 1033675 D 446462 CDS YP_003098736.1 256375076 8325096 1034091..1034327 1 NC_013093.1 hypothetical protein 1034327 8325096 Amir_0930 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098736.1 1034091 D 446462 CDS YP_003098737.1 256375077 8325097 1034760..1035653 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: smt:Smal_2740 ubiquinone biosynthesis O- methyltransferase; type 12 methyltransferase 1035653 8325097 Amir_0931 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003098737.1 1034760 D 446462 CDS YP_003098738.1 256375078 8325099 complement(1036103..1036660) 1 NC_013093.1 hypothetical protein 1036660 8325099 Amir_0933 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098738.1 1036103 R 446462 CDS YP_003098739.1 256375079 8325100 complement(1036772..1038082) 1 NC_013093.1 PFAM: ABC-1 domain protein; KEGG: mxa:MXAN_0725 ABC1 domain protein; ABC transporter 1038082 8325100 Amir_0934 Actinosynnema mirum DSM 43827 ABC transporter YP_003098739.1 1036772 R 446462 CDS YP_003098740.1 256375080 8325101 complement(1038592..1039698) 1 NC_013093.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ank:AnaeK_3014 UBA/ThiF-type NAD/FAD binding protein; UBA/THIF-type NAD/FAD binding protein 1039698 8325101 Amir_0935 Actinosynnema mirum DSM 43827 UBA/THIF-type NAD/FAD binding protein YP_003098740.1 1038592 R 446462 CDS YP_003098741.1 256375081 8325102 complement(1039978..1040133) 1 NC_013093.1 hypothetical protein 1040133 8325102 Amir_0936 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098741.1 1039978 R 446462 CDS YP_003098742.1 256375082 8325103 1040335..1040862 1 NC_013093.1 PFAM: protein of unknown function DUF45; KEGG: gox:GOX1405 hypothetical protein; hypothetical protein 1040862 8325103 Amir_0937 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098742.1 1040335 D 446462 CDS YP_003098743.1 256375083 8325104 complement(1040866..1042308) 1 NC_013093.1 KEGG: met:M446_4394 NADH-quinone oxidoreductase, E subunit; hypothetical protein 1042308 8325104 Amir_0938 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098743.1 1040866 R 446462 CDS YP_003098744.1 256375084 8325105 1042388..1043548 1 NC_013093.1 PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: bha:BH2586 hypothetical protein; PDZ/DHR/GLGF domain-containing protein 1043548 8325105 Amir_0939 Actinosynnema mirum DSM 43827 PDZ/DHR/GLGF domain-containing protein YP_003098744.1 1042388 D 446462 CDS YP_003098745.1 256375085 8325106 complement(1043630..1044172) 1 NC_013093.1 hypothetical protein 1044172 8325106 Amir_0940 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098745.1 1043630 R 446462 CDS YP_003098746.1 256375086 8325107 1044282..1047287 1 NC_013093.1 PFAM: protein of unknown function UPF0182; KEGG: reh:H16_A1615 hypothetical membrane spanning protein; hypothetical protein 1047287 8325107 Amir_0941 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098746.1 1044282 D 446462 CDS YP_003098747.1 256375087 8325111 complement(1048143..1048343) 1 NC_013093.1 hypothetical protein 1048343 8325111 Amir_0942 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098747.1 1048143 R 446462 CDS YP_003098748.1 256375088 8325112 1048791..1049291 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: scl:sce6005 transcriptional regulator; PadR family transcriptional regulator 1049291 8325112 Amir_0943 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003098748.1 1048791 D 446462 CDS YP_003098749.1 256375089 8325113 1049362..1050465 1 NC_013093.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: gsu:GSU2278 peptide chain release factor 2; peptide chain release factor 2 1050465 8325113 Amir_0944 Actinosynnema mirum DSM 43827 peptide chain release factor 2 YP_003098749.1 1049362 D 446462 CDS YP_003098750.1 256375090 8325114 1050653..1051342 1 NC_013093.1 KEGG: bsu:BSU35260 cell-division ATP-binding protein; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter; SMART: ATPase AAA; cell division ATP-binding protein FtsE 1051342 8325114 Amir_0945 Actinosynnema mirum DSM 43827 cell division ATP-binding protein FtsE YP_003098750.1 1050653 D 446462 CDS YP_003098751.1 256375091 8325115 1051381..1052283 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: ppd:Ppro_2411 hypothetical protein; cell division protein FtsX 1052283 8325115 Amir_0946 Actinosynnema mirum DSM 43827 cell division protein FtsX YP_003098751.1 1051381 D 446462 CDS YP_003098752.1 256375092 8325116 1052314..1052799 1 NC_013093.1 TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; KEGG: ppd:Ppro_1314 SsrA-binding protein; SsrA-binding protein 1052799 8325116 Amir_0947 Actinosynnema mirum DSM 43827 SsrA-binding protein YP_003098752.1 1052314 D 446462 CDS YP_003098753.1 256375093 8325117 complement(1052864..1053508) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: tgr:Tgr7_2171 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator 1053508 8325117 Amir_0948 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003098753.1 1052864 R 446462 CDS YP_003098754.1 256375094 8325118 complement(1053496..1054746) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sus:Acid_2792 PAS/PAC sensor signal transduction histidine kinase; histidine kinase 1054746 8325118 Amir_0949 Actinosynnema mirum DSM 43827 histidine kinase YP_003098754.1 1053496 R 446462 CDS YP_003098755.1 256375095 8325120 complement(1055339..1056070) 1 NC_013093.1 hypothetical protein 1056070 8325120 Amir_0950 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098755.1 1055339 R 446462 CDS YP_003098756.1 256375096 8325121 complement(1056385..1058703) 1 NC_013093.1 KEGG: rce:RC1_1438 ATP-dependent helicase protein, TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; ATP-dependent helicase HrpB 1058703 8325121 Amir_0951 Actinosynnema mirum DSM 43827 ATP-dependent helicase HrpB YP_003098756.1 1056385 R 446462 CDS YP_003098757.1 256375097 8325122 1058720..1059853 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: gbe:GbCGDNIH1_1979 HpnB protein; family 2 glycosyl transferase 1059853 8325122 Amir_0952 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003098757.1 1058720 D 446462 CDS YP_003098758.1 256375098 8325123 1059858..1060682 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mlo:mlr0192 hypothetical protein; GCN5-like N-acetyltransferase 1060682 8325123 Amir_0953 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003098758.1 1059858 D 446462 CDS YP_003098759.1 256375099 8325124 1060794..1062101 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: afw:Anae109_0137 major facilitator transporter; major facilitator superfamily protein 1062101 8325124 Amir_0954 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098759.1 1060794 D 446462 CDS YP_003098760.1 256375100 8325125 1062170..1062934 1 NC_013093.1 KEGG: maq:Maqu_3013 DsbA oxidoreductase; protein-disulfide isomerase-like protein 1062934 8325125 Amir_0955 Actinosynnema mirum DSM 43827 protein-disulfide isomerase-like protein YP_003098760.1 1062170 D 446462 CDS YP_003098761.1 256375101 8325126 complement(1062951..1064255) 1 NC_013093.1 KEGG: dps:DP1266 coenzyme F390 synthetase II; phenylacetate--CoA ligase 1064255 8325126 Amir_0956 Actinosynnema mirum DSM 43827 phenylacetate--CoA ligase YP_003098761.1 1062951 R 446462 CDS YP_003098762.1 256375102 8325128 complement(1064749..1066320) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: bsu:BSU15770 protein kinase; serine/threonine protein kinase 1066320 8325128 Amir_0957 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003098762.1 1064749 R 446462 CDS YP_003098763.1 256375103 8325129 complement(1066453..1069656) 1 NC_013093.1 PFAM: protein of unknown function DUF450; SMART: DEAD-like helicase; KEGG: tbd:Tbd_2685 DEAD/DEAH box helicase; hypothetical protein 1069656 8325129 Amir_0958 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098763.1 1066453 R 446462 CDS YP_003098764.1 256375104 8325130 complement(1069664..1070992) 1 NC_013093.1 PFAM: restriction modification system DNA specificity domain; KEGG: rsh:Rsph17029_1858 restriction modification system DNA specificity subunit; restriction modification system DNA specificity domain-containing protein 1070992 8325130 Amir_0959 Actinosynnema mirum DSM 43827 restriction modification system DNA specificity domain-containing protein YP_003098764.1 1069664 R 446462 CDS YP_003098765.1 256375105 8325131 complement(1070989..1073001) 1 NC_013093.1 PFAM: N-6 DNA methylase; KEGG: hha:Hhal_1155 N-6 DNA methylase; N-6 DNA methylase 1073001 8325131 Amir_0960 Actinosynnema mirum DSM 43827 N-6 DNA methylase YP_003098765.1 1070989 R 446462 CDS YP_003098766.1 256375106 8325132 complement(1073083..1075116) 1 NC_013093.1 PFAM: N-6 DNA methylase; RNA methylase; KEGG: bvi:Bcep1808_0009 N-6 DNA methylase; N-6 DNA methylase 1075116 8325132 Amir_0961 Actinosynnema mirum DSM 43827 N-6 DNA methylase YP_003098766.1 1073083 R 446462 CDS YP_003098767.1 256375107 8325134 1077307..1078287 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1078287 8325134 Amir_0963 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098767.1 1077307 D 446462 CDS YP_003098768.1 256375108 8325135 1078411..1078551 1 NC_013093.1 hypothetical protein 1078551 8325135 Amir_0964 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098768.1 1078411 D 446462 CDS YP_003098769.1 256375109 8325136 complement(1078583..1079779) 1 NC_013093.1 KEGG: rde:RD1_2154 hypothetical protein; hypothetical protein 1079779 8325136 Amir_0965 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098769.1 1078583 R 446462 CDS YP_003098770.1 256375110 8325137 1079924..1081480 1 NC_013093.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sus:Acid_4295 response regulator receiver modulated serine phosphatase; protein serine/threonine phosphatase 1081480 8325137 Amir_0966 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003098770.1 1079924 D 446462 CDS YP_003098771.1 256375111 8325138 1081477..1082454 1 NC_013093.1 PFAM: cobalamin B12-binding domain protein; KEGG: rpc:RPC_1467 cobalamin B12-binding; cobalamin B12-binding domain-containing protein 1082454 8325138 Amir_0967 Actinosynnema mirum DSM 43827 cobalamin B12-binding domain-containing protein YP_003098771.1 1081477 D 446462 CDS YP_003098772.1 256375112 8325139 1082545..1082907 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist; anti-sigma-factor antagonist 1082907 8325139 Amir_0968 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003098772.1 1082545 D 446462 CDS YP_003098773.1 256375113 8325140 1082983..1083417 1 NC_013093.1 hypothetical protein 1083417 8325140 Amir_0969 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098773.1 1082983 D 446462 CDS YP_003098774.1 256375114 8325141 1083604..1084890 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: smd:Smed_3329 extracellular solute-binding protein family 1; family 1 extracellular solute-binding protein 1084890 8325141 Amir_0970 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003098774.1 1083604 D 446462 CDS YP_003098775.1 256375115 8325142 1084896..1085852 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 1085852 8325142 Amir_0971 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098775.1 1084896 D 446462 CDS YP_003098776.1 256375116 8325143 1085849..1086679 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04137 transport system permease ABC transporter protein; ABC transporter inner membrane protein 1086679 8325143 Amir_0972 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003098776.1 1085849 D 446462 CDS YP_003098777.1 256375117 8325144 1086676..1087242 1 NC_013093.1 KEGG: acp:A2cp1_3283 hypothetical protein; hypothetical protein 1087242 8325144 Amir_0973 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098777.1 1086676 D 446462 CDS YP_003098778.1 256375118 8325145 1087260..1087580 1 NC_013093.1 PFAM: protein of unknown function DUF718; KEGG: bcm:Bcenmc03_6232 L-rhamnose 1-epimerase; hypothetical protein 1087580 8325145 Amir_0974 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098778.1 1087260 D 446462 CDS YP_003098779.1 256375119 8325146 1087652..1088668 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: aav:Aave_4199 transcriptional regulator, LacI family; LacI family transcriptional regulator 1088668 8325146 Amir_0975 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003098779.1 1087652 D 446462 CDS YP_003098780.1 256375120 8325147 complement(1088702..1091029) 1 NC_013093.1 PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: helix-turn-helix domain protein; hypothetical protein; KEGG: scl:sce6858 hypothetical protein; XRE family transcriptional regulator 1091029 8325147 Amir_0976 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003098780.1 1088702 R 446462 CDS YP_003098781.1 256375121 8325148 1091435..1093690 1 NC_013093.1 PFAM: terpene synthase; KEGG: mxa:MXAN_6247 terpene synthase, metal binding domain protein; terpene synthase 1093690 8325148 Amir_0977 Actinosynnema mirum DSM 43827 terpene synthase YP_003098781.1 1091435 D 446462 CDS YP_003098782.1 256375122 8325149 complement(1093751..1094320) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: oan:Oant_4146 NUDIX hydrolase; NUDIX hydrolase 1094320 8325149 Amir_0978 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003098782.1 1093751 R 446462 CDS YP_003098783.1 256375123 8325150 complement(1094454..1094558) 1 NC_013093.1 hypothetical protein 1094558 8325150 Amir_0979 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098783.1 1094454 R 446462 CDS YP_003098784.1 256375124 8325151 complement(1094654..1095991) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: afw:Anae109_0769 heat shock protein DnaJ domain-containing protein; XRE family transcriptional regulator 1095991 8325151 Amir_0980 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003098784.1 1094654 R 446462 CDS YP_003098785.1 256375125 8325153 complement(1096592..1097392) 1 NC_013093.1 KEGG: scl:sce6462 hypothetical protein; hypothetical protein 1097392 8325153 Amir_0982 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098785.1 1096592 R 446462 CDS YP_003098786.1 256375126 8325154 1097714..1098841 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: azc:AZC_3175 FMNH2-dependent monooxygenase; acyl-CoA dehydrogenase type 2 domain-containing protein 1098841 8325154 Amir_0983 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003098786.1 1097714 D 446462 CDS YP_003098787.1 256375127 8325155 1098842..1099873 1 NC_013093.1 KEGG: aba:Acid345_1175 translation initiation factor 2B subunit I family (IF-2BI); TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; eIF-2B alpha/beta/delta-like protein 1099873 8325155 Amir_0984 Actinosynnema mirum DSM 43827 eIF-2B alpha/beta/delta-like protein YP_003098787.1 1098842 D 446462 CDS YP_003098788.1 256375128 8325156 1099866..1100540 1 NC_013093.1 TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tgr:Tgr7_2625 2,3-diketo-5-methylthio-1- phosphopentane phosphatase; 2, 3-diketo-5-methylthio-1-phosphopentanephosphatase 1100540 8325156 Amir_0985 Actinosynnema mirum DSM 43827 2, 3-diketo-5-methylthio-1-phosphopentanephosphatase YP_003098788.1 1099866 D 446462 CDS YP_003098789.1 256375129 8325157 1100537..1101157 1 NC_013093.1 TIGRFAM: methylthioribulose-1-phosphate dehydratase; PFAM: class II aldolase/adducin family protein; KEGG: tgr:Tgr7_2623 methylthioribulose-1-phosphate dehydratase; methylthioribulose-1-phosphate dehydratase 1101157 8325157 Amir_0986 Actinosynnema mirum DSM 43827 methylthioribulose-1-phosphate dehydratase YP_003098789.1 1100537 D 446462 CDS YP_003098790.1 256375130 8325158 1101154..1101723 1 NC_013093.1 PFAM: acireductone dioxygenase ARD; KEGG: tgr:Tgr7_2624 acireductone dioxygenase ARD; acireductone dioxygenase ARD 1101723 8325158 Amir_0987 Actinosynnema mirum DSM 43827 acireductone dioxygenase ARD YP_003098790.1 1101154 D 446462 CDS YP_003098791.1 256375131 8325159 complement(1101756..1102631) 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: cvi:CV_1007 serine/threonine protein kinase; aminoglycoside phosphotransferase 1102631 8325159 Amir_0988 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003098791.1 1101756 R 446462 CDS YP_003098792.1 256375132 8325160 1103164..1104954 1 NC_013093.1 KEGG: bha:BH2614 cytochrome Caa3 oxidase (subunit I); TIGRFAM: cytochrome C oxidase, subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase, subunit I 1104954 8325160 Amir_0989 Actinosynnema mirum DSM 43827 cytochrome C oxidase, subunit I YP_003098792.1 1103164 D 446462 CDS YP_003098793.1 256375133 8325161 1105046..1106266 1 NC_013093.1 KEGG: scl:sce0663 hypothetical protein; TIGRFAM: phosphoserine phosphatase SerB; HAD- superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein; phosphoserine phosphatase SerB 1106266 8325161 Amir_0990 Actinosynnema mirum DSM 43827 phosphoserine phosphatase SerB YP_003098793.1 1105046 D 446462 CDS YP_003098794.1 256375134 8325162 1106263..1107048 1 NC_013093.1 PFAM: protein of unknown function UPF0099; KEGG: predicted protein; K04794 peptidyl-tRNA hydrolase, PTH2 family; hypothetical protein 1107048 8325162 Amir_0991 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098794.1 1106263 D 446462 CDS YP_003098795.1 256375135 8325163 1108027..1108824 1 NC_013093.1 hypothetical protein 1108824 8325163 Amir_0992 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098795.1 1108027 D 446462 CDS YP_003098796.1 256375136 8325165 1109105..1110517 1 NC_013093.1 KEGG: phospholipase/phosphatidylserine synthase; PFAM: phospholipase D/transphosphatidylase; SMART: phospholipase D/transphosphatidylase; phospholipase D 1110517 8325165 Amir_0994 Actinosynnema mirum DSM 43827 phospholipase D YP_003098796.1 1109105 D 446462 CDS YP_003098797.1 256375137 8325166 complement(1110535..1112580) 1 NC_013093.1 SMART: helicase c2; DEAD-like helicase; KEGG: mxa:MXAN_6717 ATP-dependent helicase; helicase c2 1112580 8325166 Amir_0995 Actinosynnema mirum DSM 43827 helicase c2 YP_003098797.1 1110535 R 446462 CDS YP_003098798.1 256375138 8325167 complement(1112737..1113312) 1 NC_013093.1 PFAM: BioY protein; KEGG: mxa:MXAN_2207 BioY family protein; BioY protein 1113312 8325167 Amir_0996 Actinosynnema mirum DSM 43827 BioY protein YP_003098798.1 1112737 R 446462 CDS YP_003098799.1 256375139 8325168 complement(1113448..1114800) 1 NC_013093.1 KEGG: cak:Caul_0228 polysaccharide deacetylase; cell wall biogenesis glycosyltransferase 1114800 8325168 Amir_0997 Actinosynnema mirum DSM 43827 cell wall biogenesis glycosyltransferase YP_003098799.1 1113448 R 446462 CDS YP_003098800.1 256375140 8325169 complement(1114797..1115312) 1 NC_013093.1 hypothetical protein 1115312 8325169 Amir_0998 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098800.1 1114797 R 446462 CDS YP_003098801.1 256375141 8325170 1115593..1116381 1 NC_013093.1 KEGG: ect:ECIAI39_4258 invasin/intimin protein; hypothetical protein 1116381 8325170 Amir_0999 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098801.1 1115593 D 446462 CDS YP_003098802.1 256375142 8325171 1116378..1116551 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; LPXTG-motif cell wall anchor domain-containing protein 1116551 8325171 Amir_1000 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003098802.1 1116378 D 446462 CDS YP_003098803.1 256375143 8325172 1116623..1117795 1 NC_013093.1 KEGG: rso:RSp0510 UDP-N-acetylglucosamine 2- epimerase protein; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 1117795 8325172 Amir_1001 Actinosynnema mirum DSM 43827 UDP-N-acetylglucosamine 2-epimerase YP_003098803.1 1116623 D 446462 CDS YP_003098804.1 256375144 8325173 1117922..1118578 1 NC_013093.1 hypothetical protein 1118578 8325173 Amir_1002 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098804.1 1117922 D 446462 CDS YP_003098805.1 256375145 8325174 complement(1118721..1119290) 1 NC_013093.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMc02275 pyrazinamidase/nicotinamidase (includes: pyrazinamidase, nicotinamidase) protein; isochorismatase hydrolase 1119290 8325174 Amir_1003 Actinosynnema mirum DSM 43827 isochorismatase hydrolase YP_003098805.1 1118721 R 446462 CDS YP_003098806.1 256375146 8325175 complement(1119301..1120614) 1 NC_013093.1 TIGRFAM: nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; KEGG: rpi:Rpic_4654 nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase 1120614 8325175 Amir_1004 Actinosynnema mirum DSM 43827 nicotinate phosphoribosyltransferase YP_003098806.1 1119301 R 446462 CDS YP_003098807.1 256375147 8325176 1120667..1120966 1 NC_013093.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: bbr:BB2017 ATP-dependent Clp protease adaptor protein ClpS; ATP-dependent Clp protease adaptor protein ClpS 1120966 8325176 Amir_1005 Actinosynnema mirum DSM 43827 ATP-dependent Clp protease adaptor protein ClpS YP_003098807.1 1120667 D 446462 CDS YP_003098808.1 256375148 8325177 1120963..1121520 1 NC_013093.1 hypothetical protein 1121520 8325177 Amir_1006 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098808.1 1120963 D 446462 CDS YP_003098809.1 256375149 8325178 1121517..1122131 1 NC_013093.1 KEGG: aav:Aave_1804 peptidase S58, DmpA; peptidase S58, DmpA 1122131 8325178 Amir_1007 Actinosynnema mirum DSM 43827 peptidase S58, DmpA YP_003098809.1 1121517 D 446462 CDS YP_003098810.1 256375150 8325179 1122293..1122862 1 NC_013093.1 KEGG: scl:sce7049 hypothetical protein; hypothetical protein 1122862 8325179 Amir_1008 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098810.1 1122293 D 446462 CDS YP_003098811.1 256375151 8325180 1122872..1123327 1 NC_013093.1 PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: nmu:Nmul_A0971 Mov34/MPN/PAD-1; Mov34/MPN/PAD-1 family protein 1123327 8325180 Amir_1009 Actinosynnema mirum DSM 43827 Mov34/MPN/PAD-1 family protein YP_003098811.1 1122872 D 446462 CDS YP_003098812.1 256375152 8325181 1123390..1123662 1 NC_013093.1 PFAM: thiamineS protein; KEGG: hch:HCH_02849 molybdopterin converting factor, small subunit; sulfur carrier protein ThiS 1123662 8325181 Amir_1010 Actinosynnema mirum DSM 43827 sulfur carrier protein ThiS YP_003098812.1 1123390 D 446462 CDS YP_003098813.1 256375153 8325182 1123670..1124620 1 NC_013093.1 TIGRFAM: cysteine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: reh:H16_A0807 cysteine synthase; cysteine synthase 1124620 8325182 Amir_1011 Actinosynnema mirum DSM 43827 cysteine synthase YP_003098813.1 1123670 D 446462 CDS YP_003098814.1 256375154 8325183 1125224..1125994 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: bcr:BCAH187_A1247 metallo-beta-lactamase family protein; beta-lactamase domain-containing protein 1125994 8325183 Amir_1012 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003098814.1 1125224 D 446462 CDS YP_003098815.1 256375155 8325184 complement(1126035..1126871) 1 NC_013093.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: sal:Sala_3160 senescence marker protein-30 (SMP-30); SMP-30/Gluconolaconase/LRE domain-containing protein 1126871 8325184 Amir_1013 Actinosynnema mirum DSM 43827 SMP-30/Gluconolaconase/LRE domain-containing protein YP_003098815.1 1126035 R 446462 CDS YP_003098816.1 256375156 8325185 1127087..1127722 1 NC_013093.1 PFAM: rhomboid family protein; KEGG: amc:MADE_01334 rhomboid-like protein; rhomboid family protein 1127722 8325185 Amir_1014 Actinosynnema mirum DSM 43827 rhomboid family protein YP_003098816.1 1127087 D 446462 CDS YP_003098817.1 256375157 8325186 1127719..1128513 1 NC_013093.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1128513 8325186 Amir_1015 Actinosynnema mirum DSM 43827 glutamate racemase YP_003098817.1 1127719 D 446462 CDS YP_003098818.1 256375158 8325187 1128531..1129343 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: dal:Dalk_3435 beta-lactamase domain protein; beta-lactamase domain-containing protein 1129343 8325187 Amir_1016 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003098818.1 1128531 D 446462 CDS YP_003098819.1 256375159 8325188 1129333..1129836 1 NC_013093.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: scl:sce7477 hypothetical protein; Hemerythrin HHE cation binding domain-containing protein 1129836 8325188 Amir_1017 Actinosynnema mirum DSM 43827 Hemerythrin HHE cation binding domain-containing protein YP_003098819.1 1129333 D 446462 CDS YP_003098820.1 256375160 8325189 1129893..1130321 1 NC_013093.1 PFAM: OsmC family protein; KEGG: mxa:MXAN_2740 OsmC/Ohr family protein; OsmC family protein 1130321 8325189 Amir_1018 Actinosynnema mirum DSM 43827 OsmC family protein YP_003098820.1 1129893 D 446462 CDS YP_003098821.1 256375161 8325190 complement(1130397..1130933) 1 NC_013093.1 KEGG: afw:Anae109_3915 hypothetical protein; hypothetical protein 1130933 8325190 Amir_1019 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098821.1 1130397 R 446462 CDS YP_003098822.1 256375162 8325191 1130987..1131751 1 NC_013093.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1131751 rph 8325191 rph Actinosynnema mirum DSM 43827 ribonuclease PH YP_003098822.1 1130987 D 446462 CDS YP_003098823.1 256375163 8325192 1131748..1132344 1 NC_013093.1 TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein; KEGG: dds:Ddes_1892 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 1132344 8325192 Amir_1021 Actinosynnema mirum DSM 43827 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase YP_003098823.1 1131748 D 446462 CDS YP_003098824.1 256375164 8325193 complement(1132329..1133312) 1 NC_013093.1 KEGG: bph:Bphy_3741 hypothetical protein; hypothetical protein 1133312 8325193 Amir_1022 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098824.1 1132329 R 446462 CDS YP_003098825.1 256375165 8325194 complement(1133344..1133817) 1 NC_013093.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: yen:YE1135 thioredoxin-dependent thiol peroxidase; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 1133817 8325194 Amir_1023 Actinosynnema mirum DSM 43827 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_003098825.1 1133344 R 446462 CDS YP_003098826.1 256375166 8325195 complement(1133839..1134366) 1 NC_013093.1 KEGG: aba:Acid345_1279 hypothetical protein; hypothetical protein 1134366 8325195 Amir_1024 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098826.1 1133839 R 446462 CDS YP_003098827.1 256375167 8325196 complement(1134651..1135673) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: bvi:Bcep1808_1087 luciferase family protein; luciferase-like monooxygenase 1135673 8325196 Amir_1025 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003098827.1 1134651 R 446462 CDS YP_003098828.1 256375168 8325197 1135785..1136843 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: oan:Oant_2127 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1136843 8325197 Amir_1026 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003098828.1 1135785 D 446462 CDS YP_003098829.1 256375169 8325198 complement(1137043..1138020) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: pde:Pden_3867 DedA family protein; hypothetical protein 1138020 8325198 Amir_1027 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098829.1 1137043 R 446462 CDS YP_003098830.1 256375170 8325199 1138127..1139095 1 NC_013093.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: vvu:VV1_0002 GTPase; cobalamin synthesis protein P47K 1139095 8325199 Amir_1028 Actinosynnema mirum DSM 43827 cobalamin synthesis protein P47K YP_003098830.1 1138127 D 446462 CDS YP_003098831.1 256375171 8325201 1139490..1139711 1 NC_013093.1 hypothetical protein 1139711 8325201 Amir_1029 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098831.1 1139490 D 446462 CDS YP_003098832.1 256375172 8325202 complement(1139765..1140379) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bat:BAS3063 TetR family transcriptional regulator; TetR family transcriptional regulator 1140379 8325202 Amir_1030 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098832.1 1139765 R 446462 CDS YP_003098833.1 256375173 8325203 1140617..1141555 1 NC_013093.1 PFAM: esterase; KEGG: mxa:MXAN_4935 esterase; esterase 1141555 8325203 Amir_1031 Actinosynnema mirum DSM 43827 esterase YP_003098833.1 1140617 D 446462 CDS YP_003098834.1 256375174 8325204 1141662..1142696 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: rso:RSc0624 zinc-dependent alcohol dehydrogenase oxidoreductase protein; alcohol dehydrogenase GroES domain-containing protein 1142696 8325204 Amir_1032 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003098834.1 1141662 D 446462 CDS YP_003098835.1 256375175 8325205 complement(1142764..1143471) 1 NC_013093.1 PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: rsh:Rsph17029_3564 cobyric acid synthase; CobB/CobQ domain-containing protein glutamine amidotransferase 1143471 8325205 Amir_1033 Actinosynnema mirum DSM 43827 CobB/CobQ domain-containing protein glutamine amidotransferase YP_003098835.1 1142764 R 446462 CDS YP_003098836.1 256375176 8325206 complement(1143461..1144645) 1 NC_013093.1 PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; KEGG: ilo:IL0432 UDP-N-acetylmuramyl pentapeptide synthase; hypothetical protein 1144645 8325206 Amir_1034 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098836.1 1143461 R 446462 CDS YP_003098837.1 256375177 8325207 complement(1144758..1145237) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: reu:Reut_A1326 anaerobic benzoate catabolism transcriptional regulator; XRE family transcriptional regulator 1145237 8325207 Amir_1035 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003098837.1 1144758 R 446462 CDS YP_003098838.1 256375178 8325208 complement(1145358..1146104) 1 NC_013093.1 PFAM: protein of unknown function DUF218; KEGG: mxa:MXAN_6927 SanA protein; hypothetical protein 1146104 8325208 Amir_1036 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098838.1 1145358 R 446462 CDS YP_003098839.1 256375179 8325209 complement(1146600..1148798) 1 NC_013093.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bce:BC5265 membrane-bound transcriptional regulator LytR; cell envelope-related transcriptional attenuator 1148798 8325209 Amir_1037 Actinosynnema mirum DSM 43827 cell envelope-related transcriptional attenuator YP_003098839.1 1146600 R 446462 CDS YP_003098840.1 256375180 8325210 1148989..1151952 1 NC_013093.1 KEGG: hypothetical protein; K01878 glycyl-tRNA synthetase alpha chain; TIGRFAM: glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit; glycyl- tRNA synthetase beta subunit; glycyl-tRNA synthetase subunit beta 1151952 8325210 Amir_1038 Actinosynnema mirum DSM 43827 glycyl-tRNA synthetase subunit beta YP_003098840.1 1148989 D 446462 CDS YP_003098841.1 256375181 8325211 complement(1152123..1153850) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: hypothetical protein; peptidase S8/S53 subtilisin kexin sedolisin 1153850 8325211 Amir_1039 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003098841.1 1152123 R 446462 CDS YP_003098842.1 256375182 8325212 1154158..1155252 1 NC_013093.1 KEGG: rpi:Rpic_4074 D-xylose ABC transporter, periplasmic substrate-binding protein; Monosaccharide-transporting ATPase 1155252 8325212 Amir_1040 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003098842.1 1154158 D 446462 CDS YP_003098843.1 256375183 8325213 complement(1155319..1156041) 1 NC_013093.1 KEGG: aba:Acid345_1276 hypothetical protein; hypothetical protein 1156041 8325213 Amir_1041 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098843.1 1155319 R 446462 CDS YP_003098844.1 256375184 8325214 1156638..1156844 1 NC_013093.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mpt:Mpe_A2202 cold-shock DNA-binding protein family protein; cold-shock DNA-binding domain-containing protein 1156844 8325214 Amir_1042 Actinosynnema mirum DSM 43827 cold-shock DNA-binding domain-containing protein YP_003098844.1 1156638 D 446462 CDS YP_003098845.1 256375185 8325215 complement(1156980..1157357) 1 NC_013093.1 KEGG: cak:Caul_1308 hypothetical protein; hypothetical protein 1157357 8325215 Amir_1043 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098845.1 1156980 R 446462 CDS YP_003098846.1 256375186 8325216 complement(1157476..1159557) 1 NC_013093.1 KEGG: aba:Acid345_1677 alpha-galactosidase; PFAM: glycosyl hydrolase family 98 carbohydrate binding module; glycoside hydrolase clan GH- D; SMART: glycosyl hydrolase family 98 carbohydrate binding module; alpha-galactosidase 1159557 8325216 Amir_1044 Actinosynnema mirum DSM 43827 alpha-galactosidase YP_003098846.1 1157476 R 446462 CDS YP_003098847.1 256375187 8325217 complement(1159759..1161522) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: sse:Ssed_3347 acyl-CoA dehydrogenase-like protein; acyl-CoA dehydrogenase domain-containing protein 1161522 8325217 Amir_1045 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003098847.1 1159759 R 446462 CDS YP_003098848.1 256375188 8325218 complement(1161519..1162505) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: mxa:MXAN_7273 SWIM zinc finger domain protein; hypothetical protein 1162505 8325218 Amir_1046 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098848.1 1161519 R 446462 CDS YP_003098849.1 256375189 8325219 complement(1162498..1165584) 1 NC_013093.1 KEGG: scl:sce3369 SWF/SNF family helicase; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; Non-specific serine/threonine protein kinase 1165584 8325219 Amir_1047 Actinosynnema mirum DSM 43827 Non-specific serine/threonine protein kinase YP_003098849.1 1162498 R 446462 CDS YP_003098850.1 256375190 8325220 complement(1166313..1166585) 1 NC_013093.1 KEGG: gbm:Gbem_1481 transglycosylase-associated protein; hypothetical protein 1166585 8325220 Amir_1048 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098850.1 1166313 R 446462 CDS YP_003098851.1 256375191 8325221 complement(1166674..1167405) 1 NC_013093.1 KEGG: Hypothetical protein CBG18987; hypothetical protein 1167405 8325221 Amir_1049 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098851.1 1166674 R 446462 CDS YP_003098852.1 256375192 8325222 complement(1167448..1168533) 1 NC_013093.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: sfu:Sfum_2797 DNA-cytosine methyltransferase; DNA-cytosine methyltransferase 1168533 8325222 Amir_1050 Actinosynnema mirum DSM 43827 DNA-cytosine methyltransferase YP_003098852.1 1167448 R 446462 CDS YP_003098853.1 256375193 8325223 complement(1168548..1168973) 1 NC_013093.1 TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr; KEGG: ajs:Ajs_2197 very short patch repair protein; DNA mismatch endonuclease Vsr 1168973 8325223 Amir_1051 Actinosynnema mirum DSM 43827 DNA mismatch endonuclease Vsr YP_003098853.1 1168548 R 446462 CDS YP_003098854.1 256375194 8325224 complement(1169035..1170150) 1 NC_013093.1 KEGG: scl:sce2746 protein kinase; hypothetical protein 1170150 8325224 Amir_1052 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098854.1 1169035 R 446462 CDS YP_003098855.1 256375195 8325225 1170229..1170900 1 NC_013093.1 hypothetical protein 1170900 8325225 Amir_1053 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098855.1 1170229 D 446462 CDS YP_003098856.1 256375196 8325227 1171277..1172479 1 NC_013093.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mca:MCA1018 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 1172479 8325227 Amir_1054 Actinosynnema mirum DSM 43827 ErfK/YbiS/YcfS/YnhG family protein YP_003098856.1 1171277 D 446462 CDS YP_003098857.1 256375197 8325228 complement(1172496..1174124) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ank:AnaeK_1721 ABC transporter-related protein; ABC transporter 1174124 8325228 Amir_1055 Actinosynnema mirum DSM 43827 ABC transporter YP_003098857.1 1172496 R 446462 CDS YP_003098858.1 256375198 8325230 complement(1174327..1174953) 1 NC_013093.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1174953 8325230 Amir_1056 Actinosynnema mirum DSM 43827 oligoribonuclease YP_003098858.1 1174327 R 446462 CDS YP_003098859.1 256375199 8325231 complement(1175057..1176331) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_0079 major facilitator transporter; major facilitator superfamily protein 1176331 8325231 Amir_1057 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098859.1 1175057 R 446462 CDS YP_003098860.1 256375200 8325232 1176403..1177371 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bac:BamMC406_2532 AraC family transcriptional regulator; AraC family transcriptional regulator 1177371 8325232 Amir_1058 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003098860.1 1176403 D 446462 CDS YP_003098861.1 256375201 8325233 1177470..1178231 1 NC_013093.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: cak:Caul_0312 DeoR family transcriptional regulator; DeoR family transcriptional regulator 1178231 8325233 Amir_1059 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003098861.1 1177470 D 446462 CDS YP_003098862.1 256375202 8325234 1178228..1179154 1 NC_013093.1 TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: gbm:Gbem_3234 1-phosphofructokinase; 1-phosphofructokinase 1179154 8325234 Amir_1060 Actinosynnema mirum DSM 43827 1-phosphofructokinase YP_003098862.1 1178228 D 446462 CDS YP_003098863.1 256375203 8325235 1179151..1179600 1 NC_013093.1 TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: vco:VC0395_A1421 PTS system, fructose- specific IIABC component; PTS IIA-like nitrogen-regulatory protein PtsN 1179600 8325235 Amir_1061 Actinosynnema mirum DSM 43827 PTS IIA-like nitrogen-regulatory protein PtsN YP_003098863.1 1179151 D 446462 CDS YP_003098864.1 256375204 8325236 1179597..1181030 1 NC_013093.1 TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; KEGG: rsh:Rsph17029_0435 PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIC subunit 1181030 8325236 Amir_1062 Actinosynnema mirum DSM 43827 PTS system, fructose subfamily, IIC subunit YP_003098864.1 1179597 D 446462 CDS YP_003098865.1 256375205 8325237 complement(1181005..1182555) 1 NC_013093.1 PFAM: membrane-flanked domain; KEGG: bha:BH1721 hypothetical protein; membrane-flanked domain-containing protein 1182555 8325237 Amir_1063 Actinosynnema mirum DSM 43827 membrane-flanked domain-containing protein YP_003098865.1 1181005 R 446462 CDS YP_003098866.1 256375206 8325238 complement(1182648..1183133) 1 NC_013093.1 PFAM: membrane-flanked domain; KEGG: bsu:BSU04590 hypothetical protein; membrane-flanked domain-containing protein 1183133 8325238 Amir_1064 Actinosynnema mirum DSM 43827 membrane-flanked domain-containing protein YP_003098866.1 1182648 R 446462 CDS YP_003098867.1 256375207 8325239 complement(1183207..1183359) 1 NC_013093.1 hypothetical protein 1183359 8325239 Amir_1065 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098867.1 1183207 R 446462 CDS YP_003098868.1 256375208 8325240 complement(1183493..1185175) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: bur:Bcep18194_C6898 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 1185175 8325240 Amir_1066 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003098868.1 1183493 R 446462 CDS YP_003098869.1 256375209 8325241 complement(1185217..1185420) 1 NC_013093.1 hypothetical protein 1185420 8325241 Amir_1067 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098869.1 1185217 R 446462 CDS YP_003098870.1 256375210 8325242 complement(1185734..1186228) 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: atc:AGR_C_466 hypothetical protein; MarR family transcriptional regulator 1186228 8325242 Amir_1068 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003098870.1 1185734 R 446462 CDS YP_003098871.1 256375211 8325243 1186316..1186921 1 NC_013093.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH- dependent FMN reductase; KEGG: pmy:Pmen_1298 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 1186921 8325243 Amir_1069 Actinosynnema mirum DSM 43827 NAD(P)H dehydrogenase (quinone) YP_003098871.1 1186316 D 446462 CDS YP_003098872.1 256375212 8325244 1187090..1188232 1 NC_013093.1 KEGG: CG13731; hypothetical protein 1188232 8325244 Amir_1070 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098872.1 1187090 D 446462 CDS YP_003098873.1 256375213 8325245 1188362..1189357 1 NC_013093.1 PFAM: hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: bcm:Bcenmc03_0217 hypothetical protein; hypothetical protein 1189357 8325245 Amir_1071 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098873.1 1188362 D 446462 CDS YP_003098874.1 256375214 8325246 1189746..1190081 1 NC_013093.1 hypothetical protein 1190081 8325246 Amir_1072 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098874.1 1189746 D 446462 CDS YP_003098875.1 256375215 8325247 1190138..1192399 1 NC_013093.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1192399 8325247 Amir_1073 Actinosynnema mirum DSM 43827 bifunctional preprotein translocase subunit SecD/SecF YP_003098875.1 1190138 D 446462 CDS YP_003098876.1 256375216 8325248 1192627..1193808 1 NC_013093.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: hypothetical protein; K00101 L-lactate dehydrogenase (cytochrome); Lactate 2-monooxygenase 1193808 8325248 Amir_1074 Actinosynnema mirum DSM 43827 Lactate 2-monooxygenase YP_003098876.1 1192627 D 446462 CDS YP_003098877.1 256375217 8325249 1193875..1194735 1 NC_013093.1 KEGG: bha:BH1891 hypothetical protein; hypothetical protein 1194735 8325249 Amir_1075 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098877.1 1193875 D 446462 CDS YP_003098878.1 256375218 8325250 complement(1194739..1195434) 1 NC_013093.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: xca:xccb100_0257 transcriptional regulator, AraC family; AraC family transcriptional regulator 1195434 8325250 Amir_1076 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003098878.1 1194739 R 446462 CDS YP_003098879.1 256375219 8325251 complement(1195471..1196865) 1 NC_013093.1 PFAM: carbohydrate binding family 6; glycoside hydrolase family 16; SMART: cellulose binding type IV; KEGG: hypothetical protein; carbohydrate binding family 6 1196865 8325251 Amir_1077 Actinosynnema mirum DSM 43827 carbohydrate binding family 6 YP_003098879.1 1195471 R 446462 CDS YP_003098880.1 256375220 8325252 complement(1197132..1198799) 1 NC_013093.1 PFAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase; KEGG: hha:Hhal_2421 DNA polymerase I; DNA-directed DNA polymerase 1198799 8325252 Amir_1078 Actinosynnema mirum DSM 43827 DNA-directed DNA polymerase YP_003098880.1 1197132 R 446462 CDS YP_003098881.1 256375221 8325253 1198874..1201366 1 NC_013093.1 PFAM: hypothetical protein; KEGG: bid:Bind_1912 hypothetical protein; hypothetical protein 1201366 8325253 Amir_1079 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098881.1 1198874 D 446462 CDS YP_003098882.1 256375222 8325254 complement(1201368..1202015) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: smd:Smed_6054 methyltransferase type 11; type 11 methyltransferase 1202015 8325254 Amir_1080 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003098882.1 1201368 R 446462 CDS YP_003098883.1 256375223 8325255 complement(1202225..1203148) 1 NC_013093.1 PFAM: proline dehydrogenase; KEGG: mxa:MXAN_7405 proline dehydrogenase; proline dehydrogenase 1203148 8325255 Amir_1081 Actinosynnema mirum DSM 43827 proline dehydrogenase YP_003098883.1 1202225 R 446462 CDS YP_003098884.1 256375224 8325256 complement(1203152..1204780) 1 NC_013093.1 TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: scl:sce4459 1-pyrroline-5-carboxylate dehydrogenase; delta-1-pyrroline-5-carboxylate dehydrogenase 1204780 8325256 Amir_1082 Actinosynnema mirum DSM 43827 delta-1-pyrroline-5-carboxylate dehydrogenase YP_003098884.1 1203152 R 446462 CDS YP_003098885.1 256375225 8325257 1204900..1206438 1 NC_013093.1 KEGG: bha:BH1072 hypothetical protein; PucR family transcriptional regulator 1206438 8325257 Amir_1083 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003098885.1 1204900 D 446462 CDS YP_003098886.1 256375226 8325258 complement(1206473..1207273) 1 NC_013093.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: gox:GOX1827 inner membrane protein translocase component YidC; 60 kDa inner membrane insertion protein 1207273 8325258 Amir_1084 Actinosynnema mirum DSM 43827 60 kDa inner membrane insertion protein YP_003098886.1 1206473 R 446462 CDS YP_003098887.1 256375227 8325259 complement(1207310..1207588) 1 NC_013093.1 hypothetical protein 1207588 8325259 Amir_1085 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098887.1 1207310 R 446462 CDS YP_003098888.1 256375228 8325260 complement(1207604..1208224) 1 NC_013093.1 KEGG: bbt:BBta_0026 uridine kinase; hypothetical protein 1208224 8325260 Amir_1086 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098888.1 1207604 R 446462 CDS YP_003098889.1 256375229 8325261 complement(1208249..1208848) 1 NC_013093.1 PFAM: protein of unknown function DUF402; hypothetical protein 1208848 8325261 Amir_1087 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098889.1 1208249 R 446462 CDS YP_003098890.1 256375230 8325262 complement(1208870..1210285) 1 NC_013093.1 PFAM: GAF domain protein; transcriptional regulator domain protein; KEGG: rme:Rmet_4104 sigma54 specific transcriptional regulator with GAF sensor, fis family; phytochrome sensor protein 1210285 8325262 Amir_1088 Actinosynnema mirum DSM 43827 phytochrome sensor protein YP_003098890.1 1208870 R 446462 CDS YP_003098891.1 256375231 8325263 1210449..1211972 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_5040 aldehyde dehydrogenase family protein; aldehyde dehydrogenase 1211972 8325263 Amir_1089 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003098891.1 1210449 D 446462 CDS YP_003098892.1 256375232 8325264 1211972..1212346 1 NC_013093.1 PFAM: protein of unknown function DUF779; KEGG: mxa:MXAN_5039 hypothetical protein; hypothetical protein 1212346 8325264 Amir_1090 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098892.1 1211972 D 446462 CDS YP_003098893.1 256375233 8325265 complement(1212320..1213867) 1 NC_013093.1 PFAM: glycoside hydrolase, family 20, catalytic core; KEGG: cak:Caul_0293 beta-N-acetylhexosaminidase; beta-N-acetylhexosaminidase 1213867 8325265 Amir_1091 Actinosynnema mirum DSM 43827 beta-N-acetylhexosaminidase YP_003098893.1 1212320 R 446462 CDS YP_003098894.1 256375234 8325266 complement(1213908..1215395) 1 NC_013093.1 PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: reh:H16_B1017 protein of the adenylate cyclase family; CHAD domain containing protein 1215395 8325266 Amir_1092 Actinosynnema mirum DSM 43827 CHAD domain containing protein YP_003098894.1 1213908 R 446462 CDS YP_003098895.1 256375235 8325267 1215543..1216364 1 NC_013093.1 KEGG: mxa:MXAN_2991 adventurous gliding motility protein AglZ; hypothetical protein 1216364 8325267 Amir_1093 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098895.1 1215543 D 446462 CDS YP_003098896.1 256375236 8325268 complement(1216612..1217259) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1217259 8325268 Amir_1094 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098896.1 1216612 R 446462 CDS YP_003098897.1 256375237 8325269 complement(1217352..1218302) 1 NC_013093.1 PFAM: formyl transferase domain protein; KEGG: kpe:KPK_0268 UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; formyl transferase domain-containing protein 1218302 8325269 Amir_1095 Actinosynnema mirum DSM 43827 formyl transferase domain-containing protein YP_003098897.1 1217352 R 446462 CDS YP_003098898.1 256375238 8325270 1218379..1219956 1 NC_013093.1 PFAM: Amidohydrolase 3; amidohydrolase; KEGG: smd:Smed_5168 amidohydrolase 3; amidohydrolase 1219956 8325270 Amir_1096 Actinosynnema mirum DSM 43827 amidohydrolase YP_003098898.1 1218379 D 446462 CDS YP_003098899.1 256375239 8325271 complement(1220228..1220836) 1 NC_013093.1 KEGG: scl:sce4531 hypothetical protein; hypothetical protein 1220836 8325271 Amir_1097 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098899.1 1220228 R 446462 CDS YP_003098900.1 256375240 8325272 1221425..1222042 1 NC_013093.1 PFAM: peptidase S14 ClpP; KEGG: dal:Dalk_1458 ATP-dependent Clp protease, proteolytic subunit ClpP; endopeptidase Clp 1222042 8325272 Amir_1098 Actinosynnema mirum DSM 43827 endopeptidase Clp YP_003098900.1 1221425 D 446462 CDS YP_003098901.1 256375241 8325273 1222098..1222727 1 NC_013093.1 PFAM: peptidase S14 ClpP; KEGG: pmu:PM1976 ATP-dependent Clp protease proteolytic subunit; endopeptidase Clp 1222727 8325273 Amir_1099 Actinosynnema mirum DSM 43827 endopeptidase Clp YP_003098901.1 1222098 D 446462 CDS YP_003098902.1 256375242 8325274 1223191..1223283 1 NC_013093.1 hypothetical protein 1223283 8325274 Amir_1100 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098902.1 1223191 D 446462 CDS YP_003098903.1 256375243 8325275 1223787..1225103 1 NC_013093.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: pol:Bpro_0315 filamentation induced by cAMP protein Fic; filamentation induced by cAMP protein Fic 1225103 8325275 Amir_1101 Actinosynnema mirum DSM 43827 filamentation induced by cAMP protein Fic YP_003098903.1 1223787 D 446462 CDS YP_003098904.1 256375244 8325276 complement(1225890..1227101) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: gur:Gura_1136 helix-turn-helix domain- containing protein; XRE family transcriptional regulator 1227101 8325276 Amir_1102 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003098904.1 1225890 R 446462 CDS YP_003098905.1 256375245 8325277 complement(1227118..1227627) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: bba:Bd2755 ATP/GTP-binding protein; NUDIX hydrolase 1227627 8325277 Amir_1103 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003098905.1 1227118 R 446462 CDS YP_003098906.1 256375246 8325278 1227842..1228081 1 NC_013093.1 hypothetical protein 1228081 8325278 Amir_1104 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098906.1 1227842 D 446462 CDS YP_003098907.1 256375247 8325279 1228087..1228410 1 NC_013093.1 hypothetical protein 1228410 8325279 Amir_1105 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098907.1 1228087 D 446462 CDS YP_003098908.1 256375248 8325280 1228442..1229353 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: sal:Sala_1765 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 1229353 8325280 Amir_1106 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003098908.1 1228442 D 446462 CDS YP_003098909.1 256375249 8325281 complement(1229350..1230756) 1 NC_013093.1 KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein 1230756 8325281 Amir_1107 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098909.1 1229350 R 446462 CDS YP_003098910.1 256375250 8325282 complement(1230943..1231323) 1 NC_013093.1 PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dac:Daci_0148 histidine utilization repressor; GntR family transcriptional regulator 1231323 8325282 Amir_1108 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003098910.1 1230943 R 446462 CDS YP_003098911.1 256375251 8325283 1231458..1231850 1 NC_013093.1 hypothetical protein 1231850 8325283 Amir_1109 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098911.1 1231458 D 446462 CDS YP_003098912.1 256375252 8325284 1232060..1232389 1 NC_013093.1 hypothetical protein 1232389 8325284 Amir_1110 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098912.1 1232060 D 446462 CDS YP_003098913.1 256375253 8325285 1232386..1232634 1 NC_013093.1 hypothetical protein 1232634 8325285 Amir_1111 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098913.1 1232386 D 446462 CDS YP_003098914.1 256375254 8325286 1232640..1232849 1 NC_013093.1 hypothetical protein 1232849 8325286 Amir_1112 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098914.1 1232640 D 446462 CDS YP_003098915.1 256375255 8325287 1232929..1234311 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: abu:Abu_1159 cell division protein FtsK; cell division protein FtsK/SpoIIIE 1234311 8325287 Amir_1113 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003098915.1 1232929 D 446462 CDS YP_003098916.1 256375256 8325288 1234308..1234730 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 1234730 8325288 Amir_1114 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003098916.1 1234308 D 446462 CDS YP_003098917.1 256375257 8325289 1234746..1235456 1 NC_013093.1 hypothetical protein 1235456 8325289 Amir_1115 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098917.1 1234746 D 446462 CDS YP_003098918.1 256375258 8325290 1235465..1236775 1 NC_013093.1 hypothetical protein 1236775 8325290 Amir_1116 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098918.1 1235465 D 446462 CDS YP_003098919.1 256375259 8325292 1236951..1238105 1 NC_013093.1 PFAM: integrase family protein; KEGG: xau:Xaut_0620 integrase family protein; integrase family protein 1238105 8325292 Amir_1118 Actinosynnema mirum DSM 43827 integrase family protein YP_003098919.1 1236951 D 446462 CDS YP_003098920.1 256375260 8325294 complement(1238363..1239415) 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: gox:GOX0577 transcriptional regulator; LacI family transcriptional regulator 1239415 8325294 Amir_1119 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003098920.1 1238363 R 446462 CDS YP_003098921.1 256375261 8325295 1239473..1240663 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: rce:RC1_3733 major facilitator superfamily (MSF) transporter; major facilitator superfamily protein 1240663 8325295 Amir_1120 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098921.1 1239473 D 446462 CDS YP_003098922.1 256375262 8325296 complement(1240629..1241213) 1 NC_013093.1 hypothetical protein 1241213 8325296 Amir_1121 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098922.1 1240629 R 446462 CDS YP_003098923.1 256375263 8325297 1241312..1243375 1 NC_013093.1 PFAM: copper resistance D domain protein; KEGG: csa:Csal_0081 hypothetical protein; copper resistance D domain-containing protein 1243375 8325297 Amir_1122 Actinosynnema mirum DSM 43827 copper resistance D domain-containing protein YP_003098923.1 1241312 D 446462 CDS YP_003098924.1 256375264 8325298 complement(1243394..1244221) 1 NC_013093.1 PFAM: ABC transporter; KEGG: ank:AnaeK_4023 ABC transporter; ABC transporter 1244221 8325298 Amir_1123 Actinosynnema mirum DSM 43827 ABC transporter YP_003098924.1 1243394 R 446462 CDS YP_003098925.1 256375265 8325299 complement(1244251..1245186) 1 NC_013093.1 KEGG: aeh:Mlg_2715 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; daunorubicin ABC transporter ATPase 1245186 8325299 Amir_1124 Actinosynnema mirum DSM 43827 daunorubicin ABC transporter ATPase YP_003098925.1 1244251 R 446462 CDS YP_003098926.1 256375266 8325300 complement(1245171..1245803) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce5643 TetR family transcriptional regulator; TetR family transcriptional regulator 1245803 8325300 Amir_1125 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003098926.1 1245171 R 446462 CDS YP_003098927.1 256375267 8325301 1246020..1246544 1 NC_013093.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: ajs:Ajs_4211 single-strand binding protein; single-strand binding protein 1246544 8325301 Amir_1126 Actinosynnema mirum DSM 43827 single-strand binding protein YP_003098927.1 1246020 D 446462 CDS YP_003098928.1 256375268 8325302 1246872..1248548 1 NC_013093.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1248548 8325302 Amir_1127 Actinosynnema mirum DSM 43827 ABC transporter ATP-binding protein YP_003098928.1 1246872 D 446462 CDS YP_003098929.1 256375269 8325303 1248616..1253604 1 NC_013093.1 KEGG: apomucin; hypothetical protein 1253604 8325303 Amir_1128 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098929.1 1248616 D 446462 CDS YP_003098930.1 256375270 8325304 1253866..1258821 1 NC_013093.1 PFAM: NAD-glutamate dehydrogenase; KEGG: pol:Bpro_3020 glutamate dehydrogenase (NAD); NAD-glutamate dehydrogenase 1258821 8325304 Amir_1129 Actinosynnema mirum DSM 43827 NAD-glutamate dehydrogenase YP_003098930.1 1253866 D 446462 CDS YP_003098931.1 256375271 8325305 complement(1258959..1260659) 1 NC_013093.1 PFAM: alpha amylase catalytic region; glycoside hydrolase starch-binding; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; alpha amylase all-beta; KEGG: sde:Sde_2938 ATPase; alpha amylase catalytic subunit 1260659 8325305 Amir_1130 Actinosynnema mirum DSM 43827 alpha amylase catalytic subunit YP_003098931.1 1258959 R 446462 CDS YP_003098932.1 256375272 8325306 1260838..1261836 1 NC_013093.1 KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 1261836 8325306 Amir_1131 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003098932.1 1260838 D 446462 CDS YP_003098933.1 256375273 8325307 1261967..1262407 1 NC_013093.1 PFAM: thioesterase superfamily protein; KEGG: xau:Xaut_1411 thioesterase superfamily protein; thioesterase superfamily protein 1262407 8325307 Amir_1132 Actinosynnema mirum DSM 43827 thioesterase superfamily protein YP_003098933.1 1261967 D 446462 CDS YP_003098934.1 256375274 8325308 1262400..1263026 1 NC_013093.1 hypothetical protein 1263026 8325308 Amir_1133 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098934.1 1262400 D 446462 CDS YP_003098935.1 256375275 8325309 complement(1263090..1264685) 1 NC_013093.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: alpha-glucosidase; K01187 alpha-glucosidase; alpha amylase catalytic subunit 1264685 8325309 Amir_1134 Actinosynnema mirum DSM 43827 alpha amylase catalytic subunit YP_003098935.1 1263090 R 446462 CDS YP_003098936.1 256375276 8325310 complement(1264763..1265146) 1 NC_013093.1 PFAM: globin; KEGG: bha:BH2854 hypothetical protein; globin 1265146 8325310 Amir_1135 Actinosynnema mirum DSM 43827 globin YP_003098936.1 1264763 R 446462 CDS YP_003098937.1 256375277 8325311 complement(1265196..1266173) 1 NC_013093.1 PFAM: MscS Mechanosensitive ion channel; KEGG: tbd:Tbd_0499 mechanosensitive ion channel; mechanosensitive ion channel MscS 1266173 8325311 Amir_1136 Actinosynnema mirum DSM 43827 mechanosensitive ion channel MscS YP_003098937.1 1265196 R 446462 CDS YP_003098938.1 256375278 8325312 complement(1266224..1268341) 1 NC_013093.1 PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: scl:sce8590 prolyl oligopeptidase; prolyl oligopeptidase 1268341 8325312 Amir_1137 Actinosynnema mirum DSM 43827 prolyl oligopeptidase YP_003098938.1 1266224 R 446462 CDS YP_003098939.1 256375279 8325313 1268495..1269157 1 NC_013093.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: aba:Acid345_4201 HNH endonuclease; HNH endonuclease 1269157 8325313 Amir_1138 Actinosynnema mirum DSM 43827 HNH endonuclease YP_003098939.1 1268495 D 446462 CDS YP_003098940.1 256375280 8325314 complement(1269177..1269764) 1 NC_013093.1 KEGG: RGD1561483, RGD1561483_predicted; similar to ankyrin repeat domain 26; hypothetical protein 1269764 8325314 Amir_1139 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098940.1 1269177 R 446462 CDS YP_003098941.1 256375281 8325315 1270087..1270323 1 NC_013093.1 hypothetical protein 1270323 8325315 Amir_1140 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098941.1 1270087 D 446462 CDS YP_003098942.1 256375282 8325316 1270310..1270792 1 NC_013093.1 hypothetical protein 1270792 8325316 Amir_1141 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098942.1 1270310 D 446462 CDS YP_003098943.1 256375283 8325317 complement(1270865..1273423) 1 NC_013093.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: scl:sce2331 membrane alanyl aminopeptidase; aminopeptidase N 1273423 8325317 Amir_1142 Actinosynnema mirum DSM 43827 aminopeptidase N YP_003098943.1 1270865 R 446462 CDS YP_003098944.1 256375284 8325318 1273645..1274259 1 NC_013093.1 hypothetical protein 1274259 8325318 Amir_1143 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098944.1 1273645 D 446462 CDS YP_003098945.1 256375285 8325319 complement(1274328..1275104) 1 NC_013093.1 KEGG: rpi:Rpic_1101 lipoprotein; lipoprotein 1275104 8325319 Amir_1144 Actinosynnema mirum DSM 43827 lipoprotein YP_003098945.1 1274328 R 446462 CDS YP_003098946.1 256375286 8325320 1275115..1275600 1 NC_013093.1 TIGRFAM: ribose 5-phosphate isomerase; sugar- phosphate isomerase, RpiB/LacA/LacB family; PFAM: ribose/galactose isomerase; KEGG: mca:MCA0043 ribose 5-phosphate isomerase B; ribose 5-phosphate isomerase 1275600 8325320 Amir_1145 Actinosynnema mirum DSM 43827 ribose 5-phosphate isomerase YP_003098946.1 1275115 D 446462 CDS YP_003098947.1 256375287 8325321 1275600..1276274 1 NC_013093.1 hypothetical protein 1276274 8325321 Amir_1146 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098947.1 1275600 D 446462 CDS YP_003098948.1 256375288 8325322 1276267..1277070 1 NC_013093.1 PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; KEGG: hypothetical protein; DNA glycosylase/AP lyase 1277070 8325322 Amir_1147 Actinosynnema mirum DSM 43827 DNA glycosylase/AP lyase YP_003098948.1 1276267 D 446462 CDS YP_003098949.1 256375289 8325323 complement(1277139..1277909) 1 NC_013093.1 KEGG: mno:Mnod_0189 periplasmic ligand- binding sensor protein; hypothetical protein 1277909 8325323 Amir_1148 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098949.1 1277139 R 446462 CDS YP_003098950.1 256375290 8325324 complement(1278030..1279232) 1 NC_013093.1 KEGG: scl:sce0310 acetyltransferase; hypothetical protein 1279232 8325324 Amir_1149 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098950.1 1278030 R 446462 CDS YP_003098951.1 256375291 8325325 complement(1279447..1280745) 1 NC_013093.1 hypothetical protein 1280745 8325325 Amir_1150 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098951.1 1279447 R 446462 CDS YP_003098952.1 256375292 8325328 complement(1281568..1282476) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bsu:BSU36160 hypothetical protein; LysR family transcriptional regulator 1282476 8325328 Amir_1151 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003098952.1 1281568 R 446462 CDS YP_003098953.1 256375293 8325329 1283560..1284912 1 NC_013093.1 TIGRFAM: trigger factor; PFAM: trigger factor domain; trigger factor domain protein; peptidylprolyl isomerase FKBP-type; KEGG: bcr:BCAH187_A4609 trigger factor; trigger factor 1284912 8325329 Amir_1152 Actinosynnema mirum DSM 43827 trigger factor YP_003098953.1 1283560 D 446462 CDS YP_003098954.1 256375294 8325330 1285072..1285701 1 NC_013093.1 PFAM: peptidase S14 ClpP; KEGG: aba:Acid345_1560 ATP-dependent Clp protease proteolytic subunit ClpP; endopeptidase Clp 1285701 8325330 Amir_1153 Actinosynnema mirum DSM 43827 endopeptidase Clp YP_003098954.1 1285072 D 446462 CDS YP_003098955.1 256375295 8325331 1285906..1287186 1 NC_013093.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1287186 clpX 8325331 clpX Actinosynnema mirum DSM 43827 ATP-dependent protease ATP-binding subunit ClpX YP_003098955.1 1285906 D 446462 CDS YP_003098956.1 256375296 8325332 1287190..1287780 1 NC_013093.1 PFAM: protein of unknown function DUF1234; KEGG: nis:NIS_1664 hypothetical protein; hypothetical protein 1287780 8325332 Amir_1155 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098956.1 1287190 D 446462 CDS YP_003098957.1 256375297 8325333 complement(1287802..1288710) 1 NC_013093.1 PFAM: esterase; KEGG: endo-1,4-beta-xylanase; esterase 1288710 8325333 Amir_1156 Actinosynnema mirum DSM 43827 esterase YP_003098957.1 1287802 R 446462 CDS YP_003098958.1 256375298 8325334 complement(1288906..1289730) 1 NC_013093.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase subunit FdhD; KEGG: ade:Adeh_0826 formate dehydrogenase family accessory protein FdhD; formate dehydrogenase family accessory protein FdhD 1289730 8325334 Amir_1157 Actinosynnema mirum DSM 43827 formate dehydrogenase family accessory protein FdhD YP_003098958.1 1288906 R 446462 CDS YP_003098959.1 256375299 8325335 1289798..1291144 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: nma:NMA1574 integral membrane transporter; major facilitator superfamily protein 1291144 8325335 Amir_1158 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098959.1 1289798 D 446462 CDS YP_003098960.1 256375300 8325336 1291141..1291293 1 NC_013093.1 hypothetical protein 1291293 8325336 Amir_1159 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098960.1 1291141 D 446462 CDS YP_003098961.1 256375301 8325337 1291305..1292855 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: acp:A2cp1_3444 amine oxidase; FAD dependent oxidoreductase 1292855 8325337 Amir_1160 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003098961.1 1291305 D 446462 CDS YP_003098962.1 256375302 8325338 complement(1292852..1293358) 1 NC_013093.1 hypothetical protein 1293358 8325338 Amir_1161 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098962.1 1292852 R 446462 CDS YP_003098963.1 256375303 8325339 complement(1293355..1295646) 1 NC_013093.1 KEGG: mxa:MXAN_4341 oxidoreductase alpha (molybdopterin) subunit; TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; oxidoreductase alpha (molybdopterin) subunit 1295646 8325339 Amir_1162 Actinosynnema mirum DSM 43827 oxidoreductase alpha (molybdopterin) subunit YP_003098963.1 1293355 R 446462 CDS YP_003098964.1 256375304 8325340 complement(1295657..1296070) 1 NC_013093.1 hypothetical protein 1296070 8325340 Amir_1163 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098964.1 1295657 R 446462 CDS YP_003098965.1 256375305 8325341 complement(1296419..1297438) 1 NC_013093.1 KEGG: ade:Adeh_3310 zinc finger/thioredoxin; hypothetical protein 1297438 8325341 Amir_1164 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098965.1 1296419 R 446462 CDS YP_003098966.1 256375306 8325342 1297729..1300362 1 NC_013093.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1300362 valS 8325342 valS Actinosynnema mirum DSM 43827 valyl-tRNA synthetase YP_003098966.1 1297729 D 446462 CDS YP_003098967.1 256375307 8325343 1300362..1301720 1 NC_013093.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase; FolC bifunctional protein 1301720 8325343 Amir_1166 Actinosynnema mirum DSM 43827 FolC bifunctional protein YP_003098967.1 1300362 D 446462 CDS YP_003098968.1 256375308 8325344 1301717..1302172 1 NC_013093.1 hypothetical protein 1302172 8325344 Amir_1167 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098968.1 1301717 D 446462 CDS YP_003098969.1 256375309 8325345 1302376..1302510 1 NC_013093.1 hypothetical protein 1302510 8325345 Amir_1168 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098969.1 1302376 D 446462 CDS YP_003098970.1 256375310 8325347 1303945..1309512 1 NC_013093.1 KEGG: aba:Acid345_2329 alpha-1,6-glucosidases, pullulanase-type; TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: alpha amylase catalytic region; pullanase- associated protein; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; alpha-1,6-glucosidase, pullulanase-type 1309512 8325347 Amir_1170 Actinosynnema mirum DSM 43827 alpha-1,6-glucosidase, pullulanase-type YP_003098970.1 1303945 D 446462 CDS YP_003098971.1 256375311 8325348 complement(1309544..1310188) 1 NC_013093.1 hypothetical protein 1310188 8325348 Amir_1171 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098971.1 1309544 R 446462 CDS YP_003098972.1 256375312 8325349 1310265..1310675 1 NC_013093.1 KEGG: bsu:BSU22730 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase; Nucleoside-diphosphate kinase 1310675 8325349 Amir_1172 Actinosynnema mirum DSM 43827 Nucleoside-diphosphate kinase YP_003098972.1 1310265 D 446462 CDS YP_003098973.1 256375313 8325350 1310810..1311730 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mgm:Mmc1_3306 ABC transporter; ABC transporter 1311730 8325350 Amir_1173 Actinosynnema mirum DSM 43827 ABC transporter YP_003098973.1 1310810 D 446462 CDS YP_003098974.1 256375314 8325351 1311730..1312566 1 NC_013093.1 PFAM: ABC transporter; KEGG: hha:Hhal_0239 ABC transporter, NodJ family; ABC transporter 1312566 8325351 Amir_1174 Actinosynnema mirum DSM 43827 ABC transporter YP_003098974.1 1311730 D 446462 CDS YP_003098975.1 256375315 8325352 1312563..1313369 1 NC_013093.1 PFAM: ABC transporter; KEGG: afr:AFE_3235 ABC transporter, permease protein, NodJ family; ABC transporter 1313369 8325352 Amir_1175 Actinosynnema mirum DSM 43827 ABC transporter YP_003098975.1 1312563 D 446462 CDS YP_003098976.1 256375316 8325353 1313403..1315370 1 NC_013093.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pca:Pcar_2585 Fe-S oxidoreductase; Radical SAM domain-containing protein 1315370 8325353 Amir_1176 Actinosynnema mirum DSM 43827 Radical SAM domain-containing protein YP_003098976.1 1313403 D 446462 CDS YP_003098977.1 256375317 8325354 1315762..1316313 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: aba:Acid345_1825 sigma-24, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 1316313 8325354 Amir_1177 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003098977.1 1315762 D 446462 CDS YP_003098978.1 256375318 8325355 1316811..1320125 1 NC_013093.1 PFAM: regulatory protein LuxR; hypothetical protein; hypothetical protein; SMART: regulatory protein LuxR; hypothetical protein; KEGG: ade:Adeh_3797 hypothetical protein; LuxR family transcriptional regulator 1320125 8325355 Amir_1178 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003098978.1 1316811 D 446462 CDS YP_003098979.1 256375319 8325358 complement(1321093..1321632) 1 NC_013093.1 PFAM: Ferric reductase domain protein transmembrane component domain; KEGG: prw:PsycPRwf_0697 ferric reductase-like protein; ferric reductase transmembrane domain-containing protein 1321632 8325358 Amir_1181 Actinosynnema mirum DSM 43827 ferric reductase transmembrane domain-containing protein YP_003098979.1 1321093 R 446462 CDS YP_003098980.1 256375320 8325359 complement(1321629..1322525) 1 NC_013093.1 PFAM: ApbE family lipoprotein; KEGG: mca:MCA2411 thiamine biosynthesis lipoprotein ApbE; ApbE family lipoprotein 1322525 8325359 Amir_1182 Actinosynnema mirum DSM 43827 ApbE family lipoprotein YP_003098980.1 1321629 R 446462 CDS YP_003098981.1 256375321 8325360 complement(1322534..1322944) 1 NC_013093.1 KEGG: HYR10; hyphally-regulated cell wall protein; hypothetical protein 1322944 8325360 Amir_1183 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098981.1 1322534 R 446462 CDS YP_003098982.1 256375322 8325361 complement(1323018..1324721) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: acp:A2cp1_0256 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 1324721 8325361 Amir_1184 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003098982.1 1323018 R 446462 CDS YP_003098983.1 256375323 8325362 1324981..1325721 1 NC_013093.1 KEGG: glo:Glov_0470 radical SAM domain protein; hypothetical protein 1325721 8325362 Amir_1185 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098983.1 1324981 D 446462 CDS YP_003098984.1 256375324 8325363 1325914..1328838 1 NC_013093.1 KEGG: sde:Sde_3188 RNAse G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: translation initiation factor IF-2 domain protein; SMART: RNA binding S1 domain protein; ribonuclease, Rne/Rng family 1328838 8325363 Amir_1186 Actinosynnema mirum DSM 43827 ribonuclease, Rne/Rng family YP_003098984.1 1325914 D 446462 CDS YP_003098985.1 256375325 8325364 1329415..1329726 1 NC_013093.1 TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: tbd:Tbd_0864 50S ribosomal protein L21P; 50S ribosomal protein L21 1329726 8325364 Amir_1187 Actinosynnema mirum DSM 43827 50S ribosomal protein L21 YP_003098985.1 1329415 D 446462 CDS YP_003098986.1 256375326 8325365 1329741..1330004 1 NC_013093.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1330004 rpmA 8325365 rpmA Actinosynnema mirum DSM 43827 50S ribosomal protein L27 YP_003098986.1 1329741 D 446462 CDS YP_003098987.1 256375327 8325366 1330117..1331583 1 NC_013093.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1331583 obgE 8325366 obgE Actinosynnema mirum DSM 43827 GTPase ObgE YP_003098987.1 1330117 D 446462 CDS YP_003098988.1 256375328 8325367 1331586..1332716 1 NC_013093.1 KEGG: mxa:MXAN_1357 glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; glutamate 5-kinase 1332716 8325367 Amir_1190 Actinosynnema mirum DSM 43827 glutamate 5-kinase YP_003098988.1 1331586 D 446462 CDS YP_003098989.1 256375329 8325368 complement(1332889..1334169) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: bav:BAV1823 alpha-ketoglutarate permease; major facilitator superfamily protein 1334169 8325368 Amir_1191 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003098989.1 1332889 R 446462 CDS YP_003098990.1 256375330 8325369 complement(1334248..1334793) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bpl:BURPS1106A_2024 acetyltransferase; GCN5-like N-acetyltransferase 1334793 8325369 Amir_1192 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003098990.1 1334248 R 446462 CDS YP_003098991.1 256375331 8325370 complement(1335135..1337210) 1 NC_013093.1 KEGG: maq:Maqu_0559 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; RecQ family ATP-dependent DNA helicase 1337210 8325370 Amir_1193 Actinosynnema mirum DSM 43827 RecQ family ATP-dependent DNA helicase YP_003098991.1 1335135 R 446462 CDS YP_003098992.1 256375332 8325371 1337301..1338563 1 NC_013093.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1338563 proA 8325371 proA Actinosynnema mirum DSM 43827 gamma-glutamyl phosphate reductase YP_003098992.1 1337301 D 446462 CDS YP_003098993.1 256375333 8325372 1338679..1339863 1 NC_013093.1 PFAM: cytochrome P450; KEGG: scl:sce8913 cytochrome P450 CYP109C2; cytochrome P450 1339863 8325372 Amir_1195 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003098993.1 1338679 D 446462 CDS YP_003098994.1 256375334 8325373 1339866..1340087 1 NC_013093.1 KEGG: bha:BH1605 ferredoxin; hypothetical protein 1340087 8325373 Amir_1196 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098994.1 1339866 D 446462 CDS YP_003098995.1 256375335 8325374 1340162..1340755 1 NC_013093.1 KEGG: bsu:BSU25640 nicotinic acid mononucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; nicotinate (nicotinamide) nucleotide adenylyltransferase 1340755 8325374 Amir_1197 Actinosynnema mirum DSM 43827 nicotinate (nicotinamide) nucleotide adenylyltransferase YP_003098995.1 1340162 D 446462 CDS YP_003098996.1 256375336 8325375 1340880..1341326 1 NC_013093.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: ank:AnaeK_0226 iojap-like protein; iojap-like protein 1341326 8325375 Amir_1198 Actinosynnema mirum DSM 43827 iojap-like protein YP_003098996.1 1340880 D 446462 CDS YP_003098997.1 256375337 8325376 1341323..1341937 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: reh:H16_A0493 phosphoglycerate mutase 2 protein; phosphoglycerate mutase 1341937 8325376 Amir_1199 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003098997.1 1341323 D 446462 CDS YP_003098998.1 256375338 8325377 1341934..1342665 1 NC_013093.1 hypothetical protein 1342665 8325377 Amir_1200 Actinosynnema mirum DSM 43827 hypothetical protein YP_003098998.1 1341934 D 446462 CDS YP_003098999.1 256375339 8325378 1342677..1343519 1 NC_013093.1 TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: bsu:BSU35480 hypothetical protein; degV family protein 1343519 8325378 Amir_1201 Actinosynnema mirum DSM 43827 degV family protein YP_003098999.1 1342677 D 446462 CDS YP_003099000.1 256375340 8325379 1343627..1344355 1 NC_013093.1 TIGRFAM: competence protein ComEA helix-hairpin- helix repeat protein; PFAM: helix-hairpin-helix motif; KEGG: bsu:BSU25590 unspecific high-affinity DNA- binding protein; competence protein ComEA helix-hairpin-helix repeat-containing protein 1344355 8325379 Amir_1202 Actinosynnema mirum DSM 43827 competence protein ComEA helix-hairpin-helix repeat-containing protein YP_003099000.1 1343627 D 446462 CDS YP_003099001.1 256375341 8325380 1344723..1347035 1 NC_013093.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase domain protein; KEGG: ank:AnaeK_2593 DNA internalization-related competence protein ComEC/Rec2; DNA internalization-related competence protein ComEC/Rec2 1347035 8325380 Amir_1203 Actinosynnema mirum DSM 43827 DNA internalization-related competence protein ComEC/Rec2 YP_003099001.1 1344723 D 446462 CDS YP_003099002.1 256375342 8325381 1347105..1347572 1 NC_013093.1 hypothetical protein 1347572 8325381 Amir_1204 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099002.1 1347105 D 446462 CDS YP_003099003.1 256375343 8325382 complement(1348001..1349266) 1 NC_013093.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1349266 8325382 Amir_1205 Actinosynnema mirum DSM 43827 threonine synthase YP_003099003.1 1348001 R 446462 CDS YP_003099004.1 256375344 8325383 1349509..1350477 1 NC_013093.1 TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: gbm:Gbem_0755 DNA polymerase III, delta subunit; hypothetical protein 1350477 8325383 Amir_1206 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099004.1 1349509 D 446462 CDS YP_003099005.1 256375345 8325384 complement(1351197..1351457) 1 NC_013093.1 TIGRFAM: ribosomal protein S20; PFAM: ribosomal protein S20; KEGG: bha:BH1339 30S ribosomal protein S20; 30S ribosomal protein S20 1351457 8325384 Amir_1207 Actinosynnema mirum DSM 43827 30S ribosomal protein S20 YP_003099005.1 1351197 R 446462 CDS YP_003099006.1 256375346 8325385 1351726..1352529 1 NC_013093.1 PFAM: protein of unknown function DUF81; KEGG: ppg:PputGB1_3567 hypothetical protein; hypothetical protein 1352529 8325385 Amir_1208 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099006.1 1351726 D 446462 CDS YP_003099007.1 256375347 8325386 complement(1352498..1353268) 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_0263 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 1353268 8325386 Amir_1209 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003099007.1 1352498 R 446462 CDS YP_003099008.1 256375348 8325387 complement(1353558..1353821) 1 NC_013093.1 KEGG: sal:Sala_0218 hypothetical protein; hypothetical protein 1353821 8325387 Amir_1210 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099008.1 1353558 R 446462 CDS YP_003099009.1 256375349 8325388 complement(1353823..1354740) 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: sml:Smlt1263 transmembrane protein; hypothetical protein 1354740 8325388 Amir_1211 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099009.1 1353823 R 446462 CDS YP_003099010.1 256375350 8325389 1354882..1355235 1 NC_013093.1 hypothetical protein 1355235 8325389 Amir_1212 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099010.1 1354882 D 446462 CDS YP_003099011.1 256375351 8325390 1355645..1357306 1 NC_013093.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: aba:Acid345_3320 protein of unknown function DUF404; hypothetical protein 1357306 8325390 Amir_1213 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099011.1 1355645 D 446462 CDS YP_003099012.1 256375352 8325391 1357306..1358250 1 NC_013093.1 PFAM: protein of unknown function DUF403; KEGG: aba:Acid345_3319 protein of unknown function DUF403; hypothetical protein 1358250 8325391 Amir_1214 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099012.1 1357306 D 446462 CDS YP_003099013.1 256375353 8325392 1358251..1359093 1 NC_013093.1 PFAM: transglutaminase domain protein; transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: ccs:CCNA_01672 transglutaminase-like enzyme, cysteine; transglutaminase domain-containing protein 1359093 8325392 Amir_1215 Actinosynnema mirum DSM 43827 transglutaminase domain-containing protein YP_003099013.1 1358251 D 446462 CDS YP_003099014.1 256375354 8325393 complement(1359587..1361428) 1 NC_013093.1 TIGRFAM: GTP-binding protein LepA; small GTP- binding protein; PFAM: GTP-binding protein LepA domain protein; elongation factor G domain protein; elongation factor Tu domain 2 protein; protein synthesis factor GTP-binding; KEGG: bcy:Bcer98_3046 GTP-binding protein LepA; GTP-binding protein LepA 1361428 8325393 Amir_1216 Actinosynnema mirum DSM 43827 GTP-binding protein LepA YP_003099014.1 1359587 R 446462 CDS YP_003099015.1 256375355 8325394 1361535..1361978 1 NC_013093.1 hypothetical protein 1361978 8325394 Amir_1217 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099015.1 1361535 D 446462 CDS YP_003099016.1 256375356 8325395 complement(1362127..1362345) 1 NC_013093.1 hypothetical protein 1362345 8325395 Amir_1218 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099016.1 1362127 R 446462 CDS YP_003099017.1 256375357 8325396 complement(1362457..1362888) 1 NC_013093.1 KEGG: pen:PSEEN1948 hypothetical protein; hypothetical protein 1362888 8325396 Amir_1219 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099017.1 1362457 R 446462 CDS YP_003099018.1 256375358 8325397 1363011..1364543 1 NC_013093.1 PFAM: carbohydrate-binding CenC domain protein; glycoside hydrolase family 18; SMART: chitinase II; KEGG: cja:CJA_2993 endo-chitinase, , chi18C; carbohydrate-binding CenC domain-containing protein 1364543 8325397 Amir_1220 Actinosynnema mirum DSM 43827 carbohydrate-binding CenC domain-containing protein YP_003099018.1 1363011 D 446462 CDS YP_003099019.1 256375359 8325398 1364625..1365668 1 NC_013093.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: bpt:Bpet3829 2-nitropropane dioxygenase; 2-nitropropane dioxygenase NPD 1365668 8325398 Amir_1221 Actinosynnema mirum DSM 43827 2-nitropropane dioxygenase NPD YP_003099019.1 1364625 D 446462 CDS YP_003099020.1 256375360 8325399 1365699..1367339 1 NC_013093.1 PFAM: protein of unknown function DUF885; KEGG: sal:Sala_0679 hypothetical protein; hypothetical protein 1367339 8325399 Amir_1222 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099020.1 1365699 D 446462 CDS YP_003099021.1 256375361 8325400 complement(1367331..1368803) 1 NC_013093.1 PFAM: amino acid permease-associated region; KEGG: bsu:BSU07340 hypothetical protein; amino acid permease-associated protein 1368803 8325400 Amir_1223 Actinosynnema mirum DSM 43827 amino acid permease-associated protein YP_003099021.1 1367331 R 446462 CDS YP_003099022.1 256375362 8325401 1369041..1369808 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: reu:Reut_A1464 enoyl-CoA hydratase; Enoyl-CoA hydratase/isomerase 1369808 8325401 Amir_1224 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003099022.1 1369041 D 446462 CDS YP_003099023.1 256375363 8325402 complement(1369842..1370810) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: xcv:XCV2170 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 1370810 8325402 Amir_1225 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003099023.1 1369842 R 446462 CDS YP_003099024.1 256375364 8325403 1370877..1371125 1 NC_013093.1 hypothetical protein 1371125 8325403 Amir_1226 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099024.1 1370877 D 446462 CDS YP_003099025.1 256375365 8325404 1371135..1371575 1 NC_013093.1 PFAM: guanine-specific ribonuclease N1 and T1; KEGG: tmz:Tmz1t_1168 guanine-specific ribonuclease N1 and T1; guanine-specific ribonuclease N1 and T1 1371575 8325404 Amir_1227 Actinosynnema mirum DSM 43827 guanine-specific ribonuclease N1 and T1 YP_003099025.1 1371135 D 446462 CDS YP_003099026.1 256375366 8325405 1371572..1371910 1 NC_013093.1 PFAM: Barstar (barnase inhibitor); KEGG: tmz:Tmz1t_1167 barstar (barnase inhibitor); Barstar (barnase inhibitor) 1371910 8325405 Amir_1228 Actinosynnema mirum DSM 43827 Barstar (barnase inhibitor) YP_003099026.1 1371572 D 446462 CDS YP_003099027.1 256375367 8325406 1372023..1372244 1 NC_013093.1 PFAM: protein of unknown function UPF0150; KEGG: dar:Daro_3012 hypothetical protein; hypothetical protein 1372244 8325406 Amir_1229 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099027.1 1372023 D 446462 CDS YP_003099028.1 256375368 8325407 1372241..1372462 1 NC_013093.1 PFAM: YcfA family protein; KEGG: abu:Abu_0898 hypothetical protein; YcfA family protein 1372462 8325407 Amir_1230 Actinosynnema mirum DSM 43827 YcfA family protein YP_003099028.1 1372241 D 446462 CDS YP_003099029.1 256375369 8325408 complement(1372542..1373258) 1 NC_013093.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: cvi:CV_1567 precorrin-8X methylmutase; cobalamin (vitamin B12) biosynthesis CbiX protein 1373258 8325408 Amir_1231 Actinosynnema mirum DSM 43827 cobalamin (vitamin B12) biosynthesis CbiX protein YP_003099029.1 1372542 R 446462 CDS YP_003099030.1 256375370 8325409 complement(1373267..1374226) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: aba:Acid345_0827 ABC aliphatic sulfonate transporter, inner membrane subunit; ABC transporter inner membrane protein 1374226 8325409 Amir_1232 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099030.1 1373267 R 446462 CDS YP_003099031.1 256375371 8325410 complement(1374207..1374995) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0826 ABC transporter, ATPase subunit; ABC transporter 1374995 8325410 Amir_1233 Actinosynnema mirum DSM 43827 ABC transporter YP_003099031.1 1374207 R 446462 CDS YP_003099032.1 256375372 8325411 complement(1375026..1376084) 1 NC_013093.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; KEGG: afw:Anae109_0427 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein 1376084 8325411 Amir_1234 Actinosynnema mirum DSM 43827 aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein YP_003099032.1 1375026 R 446462 CDS YP_003099033.1 256375373 8325412 complement(1376144..1377478) 1 NC_013093.1 KEGG: afw:Anae109_1643 sulfate adenylyltransferase, large subunit; TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; sulfate adenylyltransferase, large subunit 1377478 8325412 Amir_1235 Actinosynnema mirum DSM 43827 sulfate adenylyltransferase, large subunit YP_003099033.1 1376144 R 446462 CDS YP_003099034.1 256375374 8325413 complement(1377479..1378378) 1 NC_013093.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 1378378 8325413 Amir_1236 Actinosynnema mirum DSM 43827 sulfate adenylyltransferase subunit 2 YP_003099034.1 1377479 R 446462 CDS YP_003099035.1 256375375 8325414 complement(1378375..1379070) 1 NC_013093.1 TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate; adenylylsulfate reductase, thioredoxin dependent 1379070 8325414 Amir_1237 Actinosynnema mirum DSM 43827 adenylylsulfate reductase, thioredoxin dependent YP_003099035.1 1378375 R 446462 CDS YP_003099036.1 256375376 8325415 complement(1379067..1379225) 1 NC_013093.1 hypothetical protein 1379225 8325415 Amir_1238 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099036.1 1379067 R 446462 CDS YP_003099037.1 256375377 8325416 complement(1379222..1380934) 1 NC_013093.1 PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: aba:Acid345_2373 nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like; sulfite reductase 1380934 8325416 Amir_1239 Actinosynnema mirum DSM 43827 sulfite reductase YP_003099037.1 1379222 R 446462 CDS YP_003099038.1 256375378 8325417 1381347..1382561 1 NC_013093.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1382561 8325417 Amir_1240 Actinosynnema mirum DSM 43827 coproporphyrinogen III oxidase YP_003099038.1 1381347 D 446462 CDS YP_003099039.1 256375379 8325418 1383074..1384096 1 NC_013093.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1384096 hrcA 8325418 hrcA Actinosynnema mirum DSM 43827 heat-inducible transcription repressor YP_003099039.1 1383074 D 446462 CDS YP_003099040.1 256375380 8325419 1384183..1385337 1 NC_013093.1 PFAM: chaperone DnaJ domain protein; DnaJ central domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_2664 chaperone protein DnaJ; chaperone DnaJ domain-containing protein 1385337 8325419 Amir_1242 Actinosynnema mirum DSM 43827 chaperone DnaJ domain-containing protein YP_003099040.1 1384183 D 446462 CDS YP_003099041.1 256375381 8325420 1385334..1386068 1 NC_013093.1 PFAM: protein of unknown function DUF558; KEGG: xca:xccb100_1268 hypothetical protein; hypothetical protein 1386068 8325420 Amir_1243 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099041.1 1385334 D 446462 CDS YP_003099042.1 256375382 8325421 complement(1386261..1387475) 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce5221 hypothetical protein; G-D-S-L family lipolytic protein 1387475 8325421 Amir_1244 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003099042.1 1386261 R 446462 CDS YP_003099043.1 256375383 8325422 complement(1387590..1388834) 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce5221 hypothetical protein; G-D-S-L family lipolytic protein 1388834 8325422 Amir_1245 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003099043.1 1387590 R 446462 CDS YP_003099044.1 256375384 8325423 1389005..1389670 1 NC_013093.1 KEGG: mxa:MXAN_0913 hypothetical protein; hypothetical protein 1389670 8325423 Amir_1246 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099044.1 1389005 D 446462 CDS YP_003099045.1 256375385 8325424 1389680..1390021 1 NC_013093.1 PFAM: histidine triad (HIT) protein; KEGG: afw:Anae109_0197 histidine triad (HIT) protein; histidine triad (HIT) protein 1390021 8325424 Amir_1247 Actinosynnema mirum DSM 43827 histidine triad (HIT) protein YP_003099045.1 1389680 D 446462 CDS YP_003099046.1 256375386 8325425 complement(1390034..1390825) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_L_2832 hypothetical protein; GCN5-like N-acetyltransferase 1390825 8325425 Amir_1248 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003099046.1 1390034 R 446462 CDS YP_003099047.1 256375387 8325426 1390958..1392922 1 NC_013093.1 PFAM: PhoH family protein; SMART: Hedgehog/intein hint domain protein; KEGG: mxa:MXAN_4738 PhoH family protein; PhoH family protein 1392922 8325426 Amir_1249 Actinosynnema mirum DSM 43827 PhoH family protein YP_003099047.1 1390958 D 446462 CDS YP_003099048.1 256375388 8325427 1392928..1393491 1 NC_013093.1 PFAM: protein of unknown function UPF0054; KEGG: bsu:BSU25320 metalloprotease; metalloprotease 1393491 8325427 Amir_1250 Actinosynnema mirum DSM 43827 metalloprotease YP_003099048.1 1392928 D 446462 CDS YP_003099049.1 256375389 8325428 1393502..1394809 1 NC_013093.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; SMART: CBS domain containing protein; KEGG: scl:sce4286 hypothetical protein; CBS domain-containing protein 1394809 8325428 Amir_1251 Actinosynnema mirum DSM 43827 CBS domain-containing protein YP_003099049.1 1393502 D 446462 CDS YP_003099050.1 256375390 8325429 1394802..1395134 1 NC_013093.1 KEGG: acp:A2cp1_0654 cytidine deaminase; cytidine deaminase 1395134 8325429 Amir_1252 Actinosynnema mirum DSM 43827 cytidine deaminase YP_003099050.1 1394802 D 446462 CDS YP_003099051.1 256375391 8325430 1395135..1395479 1 NC_013093.1 KEGG: net:Neut_1332 ferredoxin 2fe-2s protein; hypothetical protein 1395479 8325430 Amir_1253 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099051.1 1395135 D 446462 CDS YP_003099052.1 256375392 8325431 1396007..1396903 1 NC_013093.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1396903 era 8325431 era Actinosynnema mirum DSM 43827 GTP-binding protein Era YP_003099052.1 1396007 D 446462 CDS YP_003099053.1 256375393 8325432 1396904..1397656 1 NC_013093.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1397656 recO 8325432 recO Actinosynnema mirum DSM 43827 DNA repair protein RecO YP_003099053.1 1396904 D 446462 CDS YP_003099054.1 256375394 8325433 1397691..1398557 1 NC_013093.1 KEGG: acr:Acry_2555 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase 1398557 8325433 Amir_1256 Actinosynnema mirum DSM 43827 undecaprenyl diphosphate synthase YP_003099054.1 1397691 D 446462 CDS YP_003099055.1 256375395 8325434 1398554..1398982 1 NC_013093.1 hypothetical protein 1398982 8325434 Amir_1257 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099055.1 1398554 D 446462 CDS YP_003099056.1 256375396 8325435 1398985..1399269 1 NC_013093.1 hypothetical protein 1399269 8325435 Amir_1258 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099056.1 1398985 D 446462 CDS YP_003099057.1 256375397 8325436 1399357..1400361 1 NC_013093.1 PFAM: permease; KEGG: bcy:Bcer98_1540 permease; permease 1400361 8325436 Amir_1259 Actinosynnema mirum DSM 43827 permease YP_003099057.1 1399357 D 446462 CDS YP_003099058.1 256375398 8325437 1400358..1401101 1 NC_013093.1 KEGG: bcy:Bcer98_1541 hypothetical protein; hypothetical protein 1401101 8325437 Amir_1260 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099058.1 1400358 D 446462 CDS YP_003099059.1 256375399 8325438 complement(1401185..1401610) 1 NC_013093.1 PFAM: ferric-uptake regulator; KEGG: gur:Gura_3002 ferric uptake regulator family protein; Fur family ferric uptake regulator 1401610 8325438 Amir_1261 Actinosynnema mirum DSM 43827 Fur family ferric uptake regulator YP_003099059.1 1401185 R 446462 CDS YP_003099060.1 256375400 8325439 complement(1401607..1402008) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: pla:Plav_2471 regulatory protein ArsR; ArsR family transcriptional regulator 1402008 8325439 Amir_1262 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003099060.1 1401607 R 446462 CDS YP_003099061.1 256375401 8325440 1402192..1402575 1 NC_013093.1 PFAM: Antibiotic biosynthesis monooxygenase; Antibiotic biosynthesis monooxygenase 1402575 8325440 Amir_1263 Actinosynnema mirum DSM 43827 Antibiotic biosynthesis monooxygenase YP_003099061.1 1402192 D 446462 CDS YP_003099062.1 256375402 8325441 1403437..1403655 1 NC_013093.1 hypothetical protein 1403655 8325441 Amir_1264 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099062.1 1403437 D 446462 CDS YP_003099063.1 256375403 8325442 1403717..1404079 1 NC_013093.1 hypothetical protein 1404079 8325442 Amir_1265 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099063.1 1403717 D 446462 CDS YP_003099064.1 256375404 8325443 1404226..1405611 1 NC_013093.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1405611 8325443 Amir_1266 Actinosynnema mirum DSM 43827 glycyl-tRNA synthetase YP_003099064.1 1404226 D 446462 CDS YP_003099065.1 256375405 8325444 1405985..1406311 1 NC_013093.1 hypothetical protein 1406311 8325444 Amir_1267 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099065.1 1405985 D 446462 CDS YP_003099066.1 256375406 8325445 1406406..1407041 1 NC_013093.1 PFAM: carbonic anhydrase; KEGG: bac:BamMC406_5701 carbonate dehydratase; carbonate dehydratase 1407041 8325445 Amir_1268 Actinosynnema mirum DSM 43827 carbonate dehydratase YP_003099066.1 1406406 D 446462 CDS YP_003099067.1 256375407 8325446 1407128..1408585 1 NC_013093.1 PFAM: sulphate transporter; xanthine/uracil/vitamin C permease; KEGG: psa:PST_4161 probable sulfate transporter; sulfate transporter 1408585 8325446 Amir_1269 Actinosynnema mirum DSM 43827 sulfate transporter YP_003099067.1 1407128 D 446462 CDS YP_003099068.1 256375408 8325447 complement(1408642..1409697) 1 NC_013093.1 PFAM: proteinase inhibitor I4 serpin; SMART: proteinase inhibitor I4 serpin; KEGG: scl:sce5377 hypothetical protein; proteinase inhibitor I4 serpin 1409697 8325447 Amir_1270 Actinosynnema mirum DSM 43827 proteinase inhibitor I4 serpin YP_003099068.1 1408642 R 446462 CDS YP_003099069.1 256375409 8325448 complement(1409766..1411016) 1 NC_013093.1 KEGG: aba:Acid345_0225 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; deoxyguanosinetriphosphate triphosphohydrolase 1411016 8325448 Amir_1271 Actinosynnema mirum DSM 43827 deoxyguanosinetriphosphate triphosphohydrolase YP_003099069.1 1409766 R 446462 CDS YP_003099070.1 256375410 8325449 complement(1411087..1411725) 1 NC_013093.1 PFAM: protein of unknown function DUF218; KEGG: aba:Acid345_2611 protein of unknown function DUF218; hypothetical protein 1411725 8325449 Amir_1272 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099070.1 1411087 R 446462 CDS YP_003099071.1 256375411 8325450 1411882..1412607 1 NC_013093.1 PFAM: peptidase S51 dipeptidase E; KEGG: bsu:BSU08780 hypothetical protein; peptidase S51 dipeptidase E 1412607 8325450 Amir_1273 Actinosynnema mirum DSM 43827 peptidase S51 dipeptidase E YP_003099071.1 1411882 D 446462 CDS YP_003099072.1 256375412 8325451 complement(1412633..1413622) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mno:Mnod_3704 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 1413622 8325451 Amir_1274 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003099072.1 1412633 R 446462 CDS YP_003099073.1 256375413 8325452 1413651..1415540 1 NC_013093.1 KEGG: DNA primase; K02316 DNA primase; TIGRFAM: DNA primase; PFAM: DNA primase catalytic core domain; zinc finger CHC2-family protein; TOPRIM domain protein; DNA primase DnaG DnaB-binding; SMART: zinc finger CHC2-family protein; DNA primase DnaG DnaB-binding; Toprim sub domain protein; DNA primase 1415540 8325452 Amir_1275 Actinosynnema mirum DSM 43827 DNA primase YP_003099073.1 1413651 D 446462 CDS YP_003099074.1 256375414 8325453 1415610..1416149 1 NC_013093.1 KEGG: reu:Reut_A2115 DNA helicase/exodeoxyribonuclease V, subunit B; hypothetical protein 1416149 8325453 Amir_1276 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099074.1 1415610 D 446462 CDS YP_003099075.1 256375415 8325454 complement(1416723..1416953) 1 NC_013093.1 hypothetical protein 1416953 8325454 Amir_1277 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099075.1 1416723 R 446462 CDS YP_003099076.1 256375416 8325455 1417386..1417943 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: kpn:KPN_04028 hypothetical protein; NUDIX hydrolase 1417943 8325455 Amir_1278 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003099076.1 1417386 D 446462 CDS YP_003099077.1 256375417 8325456 complement(1417952..1418599) 1 NC_013093.1 PFAM: protein of unknown function DUF218; KEGG: ppr:PBPRB0680 hypothetical protein; hypothetical protein 1418599 8325456 Amir_1279 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099077.1 1417952 R 446462 CDS YP_003099078.1 256375418 8325457 complement(1418628..1419329) 1 NC_013093.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: rme:Rmet_2856 transcriptional regulator, histidine utilization repressor, GntR family; GntR family transcriptional regulator 1419329 8325457 Amir_1280 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003099078.1 1418628 R 446462 CDS YP_003099079.1 256375419 8325458 complement(1419402..1420661) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: afw:Anae109_2699 response regulator receiver; XRE family transcriptional regulator 1420661 8325458 Amir_1281 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003099079.1 1419402 R 446462 CDS YP_003099080.1 256375420 8325459 complement(1420673..1421083) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: rpi:Rpic_3754 NUDIX hydrolase; NUDIX hydrolase 1421083 8325459 Amir_1282 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003099080.1 1420673 R 446462 CDS YP_003099081.1 256375421 8325460 1421239..1421991 1 NC_013093.1 PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: hypothetical protein; taurine catabolism dioxygenase TauD/TfdA 1421991 8325460 Amir_1283 Actinosynnema mirum DSM 43827 taurine catabolism dioxygenase TauD/TfdA YP_003099081.1 1421239 D 446462 CDS YP_003099082.1 256375422 8325461 1422483..1423250 1 NC_013093.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dar:Daro_2866 GntR family transcriptional regulator; GntR family transcriptional regulator 1423250 8325461 Amir_1284 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003099082.1 1422483 D 446462 CDS YP_003099083.1 256375423 8325462 1423390..1423722 1 NC_013093.1 hypothetical protein 1423722 8325462 Amir_1285 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099083.1 1423390 D 446462 CDS YP_003099084.1 256375424 8325463 1423975..1424244 1 NC_013093.1 hypothetical protein 1424244 8325463 Amir_1286 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099084.1 1423975 D 446462 CDS YP_003099085.1 256375425 8325464 1424246..1424437 1 NC_013093.1 hypothetical protein 1424437 8325464 Amir_1287 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099085.1 1424246 D 446462 CDS YP_003099086.1 256375426 8325465 1424529..1425899 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: bac:BamMC406_0006 cell divisionFtsK/SpoIIIE; cell division protein FtsK/SpoIIIE 1425899 8325465 Amir_1288 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003099086.1 1424529 D 446462 CDS YP_003099087.1 256375427 8325466 1425970..1426185 1 NC_013093.1 hypothetical protein 1426185 8325466 Amir_1289 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099087.1 1425970 D 446462 CDS YP_003099088.1 256375428 8325467 1426182..1427096 1 NC_013093.1 KEGG: hypothetical protein; K11233 osomolarity two- component system, response regulator SSK1; hypothetical protein 1427096 8325467 Amir_1290 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099088.1 1426182 D 446462 CDS YP_003099089.1 256375429 8325468 1427123..1427620 1 NC_013093.1 hypothetical protein 1427620 8325468 Amir_1291 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099089.1 1427123 D 446462 CDS YP_003099090.1 256375430 8325469 1427716..1429059 1 NC_013093.1 hypothetical protein 1429059 8325469 Amir_1292 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099090.1 1427716 D 446462 CDS YP_003099091.1 256375431 8325470 1429056..1429235 1 NC_013093.1 PFAM: regulatory protein MerR; KEGG: nwi:Nwi_0824 hypothetical protein; MerR family transcriptional regulator 1429235 8325470 Amir_1293 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003099091.1 1429056 D 446462 CDS YP_003099092.1 256375432 8325471 1429235..1430416 1 NC_013093.1 PFAM: integrase family protein; KEGG: bat:BAS0415 prophage LambdaBa04, site- specific recombinase phage integrase family protein protein; integrase family protein 1430416 8325471 Amir_1294 Actinosynnema mirum DSM 43827 integrase family protein YP_003099092.1 1429235 D 446462 CDS YP_003099093.1 256375433 8325473 complement(1430635..1431480) 1 NC_013093.1 KEGG: scl:sce5771 hypothetical protein; hypothetical protein 1431480 8325473 Amir_1295 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099093.1 1430635 R 446462 CDS YP_003099094.1 256375434 8325475 1431847..1432089 1 NC_013093.1 hypothetical protein 1432089 8325475 Amir_1296 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099094.1 1431847 D 446462 CDS YP_003099095.1 256375435 8325476 complement(1432109..1432858) 1 NC_013093.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1432858 8325476 Amir_1297 Actinosynnema mirum DSM 43827 trans-aconitate 2-methyltransferase YP_003099095.1 1432109 R 446462 CDS YP_003099096.1 256375436 8325477 1432995..1433408 1 NC_013093.1 hypothetical protein 1433408 8325477 Amir_1298 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099096.1 1432995 D 446462 CDS YP_003099097.1 256375437 8325478 complement(1433548..1434570) 1 NC_013093.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bce:BC5265 membrane-bound transcriptional regulator LytR; cell envelope-related transcriptional attenuator 1434570 8325478 Amir_1299 Actinosynnema mirum DSM 43827 cell envelope-related transcriptional attenuator YP_003099097.1 1433548 R 446462 CDS YP_003099098.1 256375438 8325479 1434624..1435049 1 NC_013093.1 KEGG: afw:Anae109_0856 hypothetical protein; hypothetical protein 1435049 8325479 Amir_1300 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099098.1 1434624 D 446462 CDS YP_003099099.1 256375439 8325480 1435129..1437042 1 NC_013093.1 PFAM: glycosyl transferase family 2; polysaccharide deacetylase; KEGG: mno:Mnod_3023 polysaccharide deacetylase; family 2 glycosyl transferase 1437042 8325480 Amir_1301 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003099099.1 1435129 D 446462 CDS YP_003099100.1 256375440 8325481 complement(1437100..1438302) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 1438302 8325481 Amir_1302 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003099100.1 1437100 R 446462 CDS YP_003099101.1 256375441 8325482 1438928..1440088 1 NC_013093.1 PFAM: nitric oxide synthase NOS; KEGG: scl:sce1582 nitric-oxide synthase, oxygenase subunit; nitric-oxide synthase 1440088 8325482 Amir_1303 Actinosynnema mirum DSM 43827 nitric-oxide synthase YP_003099101.1 1438928 D 446462 CDS YP_003099102.1 256375442 8325483 1440187..1441296 1 NC_013093.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: eba:ebA4497 pyridine nucleotide transhydrogenase alpha subunit; alanine dehydrogenase/PNT domain-containing protein 1441296 8325483 Amir_1304 Actinosynnema mirum DSM 43827 alanine dehydrogenase/PNT domain-containing protein YP_003099102.1 1440187 D 446462 CDS YP_003099103.1 256375443 8325484 complement(1441325..1441693) 1 NC_013093.1 hypothetical protein 1441693 8325484 Amir_1305 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099103.1 1441325 R 446462 CDS YP_003099104.1 256375444 8325485 complement(1441947..1444025) 1 NC_013093.1 KEGG: dvm:DvMF_0211 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; EAL domain protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 1444025 8325485 Amir_1306 Actinosynnema mirum DSM 43827 PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase YP_003099104.1 1441947 R 446462 CDS YP_003099105.1 256375445 8325486 complement(1444032..1444856) 1 NC_013093.1 PFAM: protein of unknown function DUF574; methyltransferase type 12; KEGG: scl:sce6070 hypothetical protein; hypothetical protein 1444856 8325486 Amir_1307 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099105.1 1444032 R 446462 CDS YP_003099106.1 256375446 8325487 1445048..1445617 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bmj:BMULJ_04432 MarR family transcriptional regulator; MarR family transcriptional regulator 1445617 8325487 Amir_1308 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003099106.1 1445048 D 446462 CDS YP_003099107.1 256375447 8325488 1445668..1446042 1 NC_013093.1 PFAM: camphor resistance CrcB protein; KEGG: eli:ELI_01350 hypothetical protein; camphor resistance CrcB protein 1446042 8325488 Amir_1309 Actinosynnema mirum DSM 43827 camphor resistance CrcB protein YP_003099107.1 1445668 D 446462 CDS YP_003099108.1 256375448 8325489 1446039..1446383 1 NC_013093.1 TIGRFAM: CrcB protein; PFAM: camphor resistance CrcB protein; KEGG: smd:Smed_1020 CrcB protein; CrcB protein 1446383 8325489 Amir_1310 Actinosynnema mirum DSM 43827 CrcB protein YP_003099108.1 1446039 D 446462 CDS YP_003099109.1 256375449 8325490 complement(1446409..1448655) 1 NC_013093.1 KEGG: bcr:BCAH187_A2861 UvrD/Rep helicase family protein; superfamily I DNA and RNA helicase-like protein 1448655 8325490 Amir_1311 Actinosynnema mirum DSM 43827 superfamily I DNA and RNA helicase-like protein YP_003099109.1 1446409 R 446462 CDS YP_003099110.1 256375450 8325491 1449434..1450459 1 NC_013093.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: dvm:DvMF_2927 2-hydroxy-3-oxopropionate reductase; 2-hydroxy-3-oxopropionate reductase 1450459 8325491 Amir_1312 Actinosynnema mirum DSM 43827 2-hydroxy-3-oxopropionate reductase YP_003099110.1 1449434 D 446462 CDS YP_003099111.1 256375451 8325492 1450591..1451400 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1451400 8325492 Amir_1313 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099111.1 1450591 D 446462 CDS YP_003099112.1 256375452 8325493 1451556..1452161 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mlo:mll3939 TetR family transcriptional regulator; TetR family transcriptional regulator 1452161 8325493 Amir_1314 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099112.1 1451556 D 446462 CDS YP_003099113.1 256375453 8325494 1452198..1453577 1 NC_013093.1 PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0278 mercuric reductase, truncated; pyridine nucleotide-disulfide oxidoreductase dimerization region 1453577 8325494 Amir_1315 Actinosynnema mirum DSM 43827 pyridine nucleotide-disulfide oxidoreductase dimerization region YP_003099113.1 1452198 D 446462 CDS YP_003099114.1 256375454 8325495 1453946..1454317 1 NC_013093.1 hypothetical protein 1454317 8325495 Amir_1316 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099114.1 1453946 D 446462 CDS YP_003099115.1 256375455 8325496 complement(1454359..1455615) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1455615 8325496 Amir_1317 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099115.1 1454359 R 446462 CDS YP_003099116.1 256375456 8325497 1455998..1456501 1 NC_013093.1 hypothetical protein 1456501 8325497 Amir_1318 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099116.1 1455998 D 446462 CDS YP_003099117.1 256375457 8325498 complement(1456796..1458490) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pzu:PHZ_c3203 ABC transporter, HlyB/MsbA family; ABC transporter 1458490 8325498 Amir_1319 Actinosynnema mirum DSM 43827 ABC transporter YP_003099117.1 1456796 R 446462 CDS YP_003099118.1 256375458 8325499 complement(1458690..1460552) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pzu:PHZ_c3203 ABC transporter, HlyB/MsbA family; ABC transporter 1460552 8325499 Amir_1320 Actinosynnema mirum DSM 43827 ABC transporter YP_003099118.1 1458690 R 446462 CDS YP_003099119.1 256375459 8325500 complement(1460697..1460852) 1 NC_013093.1 hypothetical protein 1460852 8325500 Amir_1321 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099119.1 1460697 R 446462 CDS YP_003099120.1 256375460 8325501 complement(1460863..1463427) 1 NC_013093.1 PFAM: lanthionine synthetase C family protein; SMART: serine/threonine protein kinase; KEGG: smt:Smal_2130 serine/threonine protein kinase; serine/threonine protein kinase 1463427 8325501 Amir_1322 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003099120.1 1460863 R 446462 CDS YP_003099121.1 256375461 8325502 1463858..1464514 1 NC_013093.1 hypothetical protein 1464514 8325502 Amir_1323 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099121.1 1463858 D 446462 CDS YP_003099122.1 256375462 8325503 complement(1464834..1466069) 1 NC_013093.1 PFAM: beta-ketoacyl synthase; KEGG: ade:Adeh_2746 3-oxoacyl-[acyl-carrier- protein] synthase II; beta-ketoacyl synthase 1466069 8325503 Amir_1324 Actinosynnema mirum DSM 43827 beta-ketoacyl synthase YP_003099122.1 1464834 R 446462 CDS YP_003099123.1 256375463 8325504 complement(1466066..1466305) 1 NC_013093.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1466305 acpP 8325504 acpP Actinosynnema mirum DSM 43827 acyl carrier protein YP_003099123.1 1466066 R 446462 CDS YP_003099124.1 256375464 8325505 complement(1466460..1467437) 1 NC_013093.1 KEGG: bha:BH2883 3-oxoacyl-(acyl carrier protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier- protein (ACP)] synthase III; 3-oxoacyl-(acyl-carrier-protein) synthase III 1467437 8325505 Amir_1326 Actinosynnema mirum DSM 43827 3-oxoacyl-(acyl-carrier-protein) synthase III YP_003099124.1 1466460 R 446462 CDS YP_003099125.1 256375465 8325506 complement(1467434..1468369) 1 NC_013093.1 PFAM: acyl transferase; KEGG: bvi:Bcep1808_1041 [acyl-carrier-protein] S- malonyltransferase; acyl transferase 1468369 8325506 Amir_1327 Actinosynnema mirum DSM 43827 acyl transferase YP_003099125.1 1467434 R 446462 CDS YP_003099126.1 256375466 8325507 complement(1468569..1469750) 1 NC_013093.1 KEGG: reu:Reut_B5661 CdaR family transcriptional regulator; PucR family transcriptional regulator 1469750 8325507 Amir_1328 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003099126.1 1468569 R 446462 CDS YP_003099127.1 256375467 8325508 1470123..1471016 1 NC_013093.1 PFAM: Conserved hypothetical protein; KEGG: pfo:Pfl01_1775 TM helix protein; hypothetical protein 1471016 8325508 Amir_1329 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099127.1 1470123 D 446462 CDS YP_003099128.1 256375468 8325509 1471751..1472449 1 NC_013093.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: mpt:Mpe_A2849 transporter; nicotinamide mononucleotide transporter PnuC 1472449 8325509 Amir_1330 Actinosynnema mirum DSM 43827 nicotinamide mononucleotide transporter PnuC YP_003099128.1 1471751 D 446462 CDS YP_003099129.1 256375469 8325510 complement(1472436..1473782) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: mxa:MXAN_7295 sugar ABC transporter, periplasmic sugar-binding protein; family 1 extracellular solute-binding protein 1473782 8325510 Amir_1331 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003099129.1 1472436 R 446462 CDS YP_003099130.1 256375470 8325511 complement(1473772..1476027) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1476027 8325511 Amir_1332 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099130.1 1473772 R 446462 CDS YP_003099131.1 256375471 8325512 complement(1476231..1478990) 1 NC_013093.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1478990 aceE 8325512 aceE Actinosynnema mirum DSM 43827 pyruvate dehydrogenase subunit E1 YP_003099131.1 1476231 R 446462 CDS YP_003099132.1 256375472 8325513 1479123..1479224 1 NC_013093.1 hypothetical protein 1479224 8325513 Amir_1334 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099132.1 1479123 D 446462 CDS YP_003099133.1 256375473 8325514 1479301..1479735 1 NC_013093.1 KEGG: ccs:CCNA_02657 hypothetical protein; hypothetical protein 1479735 8325514 Amir_1335 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099133.1 1479301 D 446462 CDS YP_003099134.1 256375474 8325515 1479850..1480308 1 NC_013093.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pzu:PHZ_p0072 peroxiredoxin; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 1480308 8325515 Amir_1336 Actinosynnema mirum DSM 43827 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_003099134.1 1479850 D 446462 CDS YP_003099135.1 256375475 8325517 complement(1480601..1480843) 1 NC_013093.1 hypothetical protein 1480843 8325517 Amir_1337 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099135.1 1480601 R 446462 CDS YP_003099136.1 256375476 8325518 1481435..1481719 1 NC_013093.1 hypothetical protein 1481719 8325518 Amir_1338 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099136.1 1481435 D 446462 CDS YP_003099137.1 256375477 8325519 1481994..1483025 1 NC_013093.1 PFAM: saccharopine dehydrogenase; KEGG: pfl:PFL_3454 hypothetical protein; saccharopine dehydrogenase 1483025 8325519 Amir_1339 Actinosynnema mirum DSM 43827 saccharopine dehydrogenase YP_003099137.1 1481994 D 446462 CDS YP_003099138.1 256375478 8325520 complement(1483000..1484004) 1 NC_013093.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1484004 8325520 Amir_1340 Actinosynnema mirum DSM 43827 lipoyl synthase YP_003099138.1 1483000 R 446462 CDS YP_003099139.1 256375479 8325521 complement(1484020..1484943) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bid:Bind_0032 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1484943 8325521 Amir_1341 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003099139.1 1484020 R 446462 CDS YP_003099140.1 256375480 8325522 1485131..1486066 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: rpi:Rpic_0157 luciferase-like monooxygenase; luciferase-like monooxygenase 1486066 8325522 Amir_1342 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003099140.1 1485131 D 446462 CDS YP_003099141.1 256375481 8325523 complement(1486216..1487214) 1 NC_013093.1 KEGG: afw:Anae109_3917 hypothetical protein; hypothetical protein 1487214 8325523 Amir_1343 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099141.1 1486216 R 446462 CDS YP_003099142.1 256375482 8325524 complement(1487308..1488051) 1 NC_013093.1 TIGRFAM: lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase; KEGG: aba:Acid345_4305 lipoate-protein ligase B; lipoate-protein ligase B 1488051 8325524 Amir_1344 Actinosynnema mirum DSM 43827 lipoate-protein ligase B YP_003099142.1 1487308 R 446462 CDS YP_003099143.1 256375483 8325525 complement(1488048..1488896) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: bxe:Bxe_B0902 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 1488896 8325525 Amir_1345 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003099143.1 1488048 R 446462 CDS YP_003099144.1 256375484 8325526 1488999..1489442 1 NC_013093.1 KEGG: bsu:BSU06870 hypothetical protein; hypothetical protein 1489442 8325526 Amir_1346 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099144.1 1488999 D 446462 CDS YP_003099145.1 256375485 8325527 1489439..1490266 1 NC_013093.1 PFAM: NmrA family protein; KEGG: scl:sce0707 hypothetical protein; NmrA family protein 1490266 8325527 Amir_1347 Actinosynnema mirum DSM 43827 NmrA family protein YP_003099145.1 1489439 D 446462 CDS YP_003099146.1 256375486 8325528 complement(1490263..1490886) 1 NC_013093.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: ade:Adeh_2905 phosphoesterase, PA-phosphatase related; PA-phosphatase-like phosphodiesterase 1490886 8325528 Amir_1348 Actinosynnema mirum DSM 43827 PA-phosphatase-like phosphodiesterase YP_003099146.1 1490263 R 446462 CDS YP_003099147.1 256375487 8325529 complement(1490886..1491779) 1 NC_013093.1 PFAM: domain of unknown function DUF1731; NAD- dependent epimerase/dehydratase; KEGG: dal:Dalk_2335 domain of unknown function DUF1731; hypothetical protein 1491779 8325529 Amir_1349 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099147.1 1490886 R 446462 CDS YP_003099148.1 256375488 8325530 complement(1491949..1493670) 1 NC_013093.1 KEGG: aba:Acid345_4350 2-oxoglutarate dehydrogenase E2 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1493670 8325530 Amir_1350 Actinosynnema mirum DSM 43827 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase YP_003099148.1 1491949 R 446462 CDS YP_003099149.1 256375489 8325531 complement(1493723..1495093) 1 NC_013093.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1495093 8325531 Amir_1351 Actinosynnema mirum DSM 43827 dihydrolipoamide dehydrogenase YP_003099149.1 1493723 R 446462 CDS YP_003099150.1 256375490 8325532 1495271..1495594 1 NC_013093.1 hypothetical protein 1495594 8325532 Amir_1352 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099150.1 1495271 D 446462 CDS YP_003099151.1 256375491 8325533 1495756..1496364 1 NC_013093.1 KEGG: scl:sce9254 secreted protein; hypothetical protein 1496364 8325533 Amir_1353 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099151.1 1495756 D 446462 CDS YP_003099152.1 256375492 8325534 complement(1496488..1497987) 1 NC_013093.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: pst:PSPTO_1271 leucyl aminopeptidase; Leucyl aminopeptidase 1497987 8325534 Amir_1354 Actinosynnema mirum DSM 43827 Leucyl aminopeptidase YP_003099152.1 1496488 R 446462 CDS YP_003099153.1 256375493 8325535 1498190..1499425 1 NC_013093.1 KEGG: bph:Bphy_0096 amino acid permease-associated region; hypothetical protein 1499425 8325535 Amir_1355 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099153.1 1498190 D 446462 CDS YP_003099154.1 256375494 8325536 1499443..1500546 1 NC_013093.1 KEGG: swi:Swit_0778 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; branched-chain amino acid aminotransferase 1500546 8325536 Amir_1356 Actinosynnema mirum DSM 43827 branched-chain amino acid aminotransferase YP_003099154.1 1499443 D 446462 CDS YP_003099155.1 256375495 8325537 complement(1500607..1501320) 1 NC_013093.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: pde:Pden_1566 cobalamin 5'-phosphate synthase; cobalamin 5'-phosphate synthase 1501320 8325537 Amir_1357 Actinosynnema mirum DSM 43827 cobalamin 5'-phosphate synthase YP_003099155.1 1500607 R 446462 CDS YP_003099156.1 256375496 8325538 complement(1501352..1502389) 1 NC_013093.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1502389 cobT 8325538 cobT Actinosynnema mirum DSM 43827 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_003099156.1 1501352 R 446462 CDS YP_003099157.1 256375497 8325539 complement(1502386..1502928) 1 NC_013093.1 PFAM: cobalbumin biosynthesis protein; KEGG: bbt:BBta_3140 adenosylcobinamide kinase; cobalbumin biosynthesis protein 1502928 8325539 Amir_1359 Actinosynnema mirum DSM 43827 cobalbumin biosynthesis protein YP_003099157.1 1502386 R 446462 CDS YP_003099158.1 256375498 8325540 complement(1503061..1504047) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: mxa:MXAN_6482 oxidoreductase, aldo/keto reductase family; aldo/keto reductase 1504047 8325540 Amir_1360 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003099158.1 1503061 R 446462 CDS YP_003099159.1 256375499 8325541 complement(1504077..1504490) 1 NC_013093.1 hypothetical protein 1504490 8325541 Amir_1361 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099159.1 1504077 R 446462 CDS YP_003099160.1 256375500 8325542 complement(1504478..1505191) 1 NC_013093.1 hypothetical protein 1505191 8325542 Amir_1362 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099160.1 1504478 R 446462 CDS YP_003099161.1 256375501 8325543 complement(1505333..1505971) 1 NC_013093.1 hypothetical protein 1505971 8325543 Amir_1363 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099161.1 1505333 R 446462 CDS YP_003099162.1 256375502 8325544 1506376..1506750 1 NC_013093.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: bvi:Bcep1808_0647 iron-sulfur cluster insertion protein ErpA; iron-sulfur cluster assembly accessory protein 1506750 8325544 Amir_1364 Actinosynnema mirum DSM 43827 iron-sulfur cluster assembly accessory protein YP_003099162.1 1506376 D 446462 CDS YP_003099163.1 256375503 8325545 complement(1506885..1507109) 1 NC_013093.1 hypothetical protein 1507109 8325545 Amir_1365 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099163.1 1506885 R 446462 CDS YP_003099164.1 256375504 8325546 complement(1507373..1509301) 1 NC_013093.1 KEGG: bsu:BSU30540 asparagine synthetase; TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; asparagine synthase 1509301 8325546 Amir_1366 Actinosynnema mirum DSM 43827 asparagine synthase YP_003099164.1 1507373 R 446462 CDS YP_003099165.1 256375505 8325547 1509507..1510442 1 NC_013093.1 TIGRFAM: cytochrome C oxidase, subunit II; PFAM: cytochrome C oxidase subunit II; KEGG: aeh:Mlg_0293 cytochrome C oxidase, subunit II; cytochrome C oxidase, subunit II 1510442 8325547 Amir_1367 Actinosynnema mirum DSM 43827 cytochrome C oxidase, subunit II YP_003099165.1 1509507 D 446462 CDS YP_003099166.1 256375506 8325548 1510453..1510869 1 NC_013093.1 cytochrome C oxidase 1510869 8325548 Amir_1368 Actinosynnema mirum DSM 43827 cytochrome C oxidase YP_003099166.1 1510453 D 446462 CDS YP_003099167.1 256375507 8325549 complement(1511336..1512055) 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: gsu:GSU3116 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase 1512055 8325549 Amir_1369 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003099167.1 1511336 R 446462 CDS YP_003099168.1 256375508 8325550 complement(1512542..1513591) 1 NC_013093.1 KEGG: mno:Mnod_5575 anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; glycosyl transferase, family 3-like; anthranilate phosphoribosyltransferase 1513591 8325550 Amir_1370 Actinosynnema mirum DSM 43827 anthranilate phosphoribosyltransferase YP_003099168.1 1512542 R 446462 CDS YP_003099169.1 256375509 8325551 complement(1513597..1514007) 1 NC_013093.1 KEGG: rpc:RPC_3025 two component transcriptional regulator; response regulator receiver protein 1514007 8325551 Amir_1371 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003099169.1 1513597 R 446462 CDS YP_003099170.1 256375510 8325552 complement(1514050..1514460) 1 NC_013093.1 hypothetical protein 1514460 8325552 Amir_1372 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099170.1 1514050 R 446462 CDS YP_003099171.1 256375511 8325553 1514534..1515148 1 NC_013093.1 PFAM: cytochrome C oxidase subunit III; KEGG: nar:Saro_0918 cytochrome C oxidase, subunit III; cytochrome C oxidase subunit III 1515148 8325553 Amir_1373 Actinosynnema mirum DSM 43827 cytochrome C oxidase subunit III YP_003099171.1 1514534 D 446462 CDS YP_003099172.1 256375512 8325554 1515190..1516002 1 NC_013093.1 PFAM: cytochrome C class I; KEGG: pne:Pnec_1360 cytochrome C oxidase, cbb3- type, subunit III; cytochrome C class I 1516002 8325554 Amir_1374 Actinosynnema mirum DSM 43827 cytochrome C class I YP_003099172.1 1515190 D 446462 CDS YP_003099173.1 256375513 8325555 1515999..1517123 1 NC_013093.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: mpt:Mpe_A0364 Rieske iron-sulfur protein; Rieske (2Fe-2S) domain-containing protein 1517123 8325555 Amir_1375 Actinosynnema mirum DSM 43827 Rieske (2Fe-2S) domain-containing protein YP_003099173.1 1515999 D 446462 CDS YP_003099174.1 256375514 8325556 1517120..1518814 1 NC_013093.1 PFAM: Cytochrome b/b6 domain; KEGG: hha:Hhal_2108 cytochrome b/b6, N-terminal domain; cytochrome b/b6 domain-containing protein 1518814 8325556 Amir_1376 Actinosynnema mirum DSM 43827 cytochrome b/b6 domain-containing protein YP_003099174.1 1517120 D 446462 CDS YP_003099175.1 256375515 8325557 complement(1518884..1519165) 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: dps:DP0751 transcription regulator; AsnC family transcriptional regulator 1519165 8325557 Amir_1377 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003099175.1 1518884 R 446462 CDS YP_003099176.1 256375516 8325558 complement(1519203..1520939) 1 NC_013093.1 contains 3'-5'exonuclease domain; hypothetical protein 1520939 8325558 Amir_1378 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099176.1 1519203 R 446462 CDS YP_003099177.1 256375517 8325559 1520999..1522552 1 NC_013093.1 PFAM: protein of unknown function DUF901; KEGG: ank:AnaeK_0136 methyltransferase type 11; hypothetical protein 1522552 8325559 Amir_1379 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099177.1 1520999 D 446462 CDS YP_003099178.1 256375518 8325560 1522952..1523983 1 NC_013093.1 PFAM: NLP/P60 protein; KEGG: dvu:DVU1392 NLP/P60 family protein; NLP/P60 protein 1523983 8325560 Amir_1380 Actinosynnema mirum DSM 43827 NLP/P60 protein YP_003099178.1 1522952 D 446462 CDS YP_003099179.1 256375519 8325561 1524106..1525338 1 NC_013093.1 KEGG: ppd:Ppro_1566 hypothetical protein; hypothetical protein 1525338 8325561 Amir_1381 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099179.1 1524106 D 446462 CDS YP_003099180.1 256375520 8325562 1525550..1526680 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: acr:Acry_1803 glycosyl transferase, group 1; group 1 glycosyl transferase 1526680 8325562 Amir_1382 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003099180.1 1525550 D 446462 CDS YP_003099181.1 256375521 8325563 complement(1526877..1528685) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: acp:A2cp1_1619 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 1528685 8325563 Amir_1383 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003099181.1 1526877 R 446462 CDS YP_003099182.1 256375522 8325564 1528815..1529195 1 NC_013093.1 hypothetical protein 1529195 8325564 Amir_1384 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099182.1 1528815 D 446462 CDS YP_003099183.1 256375523 8325565 1529207..1529995 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: sit:TM1040_3062 metallophosphoesterase; metallophosphoesterase 1529995 8325565 Amir_1385 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003099183.1 1529207 D 446462 CDS YP_003099184.1 256375524 8325566 1530023..1530457 1 NC_013093.1 PFAM: cyclase/dehydrase; KEGG: acp:A2cp1_2307 cyclase/dehydrase; cyclase/dehydrase 1530457 8325566 Amir_1386 Actinosynnema mirum DSM 43827 cyclase/dehydrase YP_003099184.1 1530023 D 446462 CDS YP_003099185.1 256375525 8325567 1530454..1531674 1 NC_013093.1 PFAM: anion-transporting ATPase; KEGG: bcz:BCZK0288 arsenite-transporting ATPase; Arsenite-transporting ATPase 1531674 8325567 Amir_1387 Actinosynnema mirum DSM 43827 Arsenite-transporting ATPase YP_003099185.1 1530454 D 446462 CDS YP_003099186.1 256375526 8325568 1531671..1532081 1 NC_013093.1 KEGG: scl:sce1096 cell wall surface anchor family protein; hypothetical protein 1532081 8325568 Amir_1388 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099186.1 1531671 D 446462 CDS YP_003099187.1 256375527 8325569 1532075..1533052 1 NC_013093.1 PFAM: ROK family protein; KEGG: mlo:mlr7234 glucose kinase; ROK family protein 1533052 8325569 Amir_1389 Actinosynnema mirum DSM 43827 ROK family protein YP_003099187.1 1532075 D 446462 CDS YP_003099188.1 256375528 8325570 1533348..1534754 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: predicted gene, 100042292; anti-sigma regulatory factor, serine/threonine protein kinase 1534754 8325570 Amir_1390 Actinosynnema mirum DSM 43827 anti-sigma regulatory factor, serine/threonine protein kinase YP_003099188.1 1533348 D 446462 CDS YP_003099189.1 256375529 8325571 complement(1534787..1535266) 1 NC_013093.1 KEGG: EP2 procyclin; hypothetical protein 1535266 8325571 Amir_1391 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099189.1 1534787 R 446462 CDS YP_003099190.1 256375530 8325572 1535477..1536214 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 1536214 8325572 Amir_1392 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003099190.1 1535477 D 446462 CDS YP_003099191.1 256375531 8325573 1536429..1536941 1 NC_013093.1 KEGG: reu:Reut_C6145 hypothetical protein; hypothetical protein 1536941 8325573 Amir_1393 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099191.1 1536429 D 446462 CDS YP_003099192.1 256375532 8325574 1537014..1538054 1 NC_013093.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1538054 8325574 Amir_1394 Actinosynnema mirum DSM 43827 6-phosphofructokinase YP_003099192.1 1537014 D 446462 CDS YP_003099193.1 256375533 8325575 1538323..1539711 1 NC_013093.1 KEGG: rce:RC1_0952 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; phospho-2-dehydro-3-deoxyheptonate aldolase 1539711 8325575 Amir_1395 Actinosynnema mirum DSM 43827 phospho-2-dehydro-3-deoxyheptonate aldolase YP_003099193.1 1538323 D 446462 CDS YP_003099194.1 256375534 8325576 complement(1539870..1542401) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; protein of unknown function RIO1; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: bha:BH2504 serine/threonine protein kinase; serine/threonine protein kinase with PASTA sensor(s) 1542401 8325576 Amir_1396 Actinosynnema mirum DSM 43827 serine/threonine protein kinase with PASTA sensor(s) YP_003099194.1 1539870 R 446462 CDS YP_003099195.1 256375535 8325577 1542650..1542988 1 NC_013093.1 hypothetical protein 1542988 8325577 Amir_1397 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099195.1 1542650 D 446462 CDS YP_003099196.1 256375536 8325578 complement(1543167..1544627) 1 NC_013093.1 KEGG: met:M446_4899 hypothetical protein; hypothetical protein 1544627 8325578 Amir_1398 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099196.1 1543167 R 446462 CDS YP_003099197.1 256375537 8325579 complement(1545067..1546575) 1 NC_013093.1 TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0895 phytoene desaturase; phytoene desaturase 1546575 8325579 Amir_1399 Actinosynnema mirum DSM 43827 phytoene desaturase YP_003099197.1 1545067 R 446462 CDS YP_003099198.1 256375538 8325580 complement(1546577..1547647) 1 NC_013093.1 PFAM: polyprenyl synthetase; KEGG: scl:sce4204 geranyltranstransferase; polyprenyl synthetase 1547647 8325580 Amir_1400 Actinosynnema mirum DSM 43827 polyprenyl synthetase YP_003099198.1 1546577 R 446462 CDS YP_003099199.1 256375539 8325581 1547753..1548643 1 NC_013093.1 KEGG: acr:Acry_0219 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase 1548643 8325581 Amir_1401 Actinosynnema mirum DSM 43827 5,10-methylenetetrahydrofolate reductase YP_003099199.1 1547753 D 446462 CDS YP_003099200.1 256375540 8325582 complement(1548687..1549127) 1 NC_013093.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: ade:Adeh_3128 alkylhydroperoxidase AhpD core; alkylhydroperoxidase like protein 1549127 8325582 Amir_1402 Actinosynnema mirum DSM 43827 alkylhydroperoxidase like protein YP_003099200.1 1548687 R 446462 CDS YP_003099201.1 256375541 8325583 complement(1549188..1549841) 1 NC_013093.1 hypothetical protein 1549841 8325583 Amir_1403 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099201.1 1549188 R 446462 CDS YP_003099202.1 256375542 8325584 1550030..1551709 1 NC_013093.1 PFAM: protein of unknown function DUF885; KEGG: scl:sce1630 hypothetical protein; hypothetical protein 1551709 8325584 Amir_1404 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099202.1 1550030 D 446462 CDS YP_003099203.1 256375543 8325585 1551911..1552534 1 NC_013093.1 hypothetical protein 1552534 8325585 Amir_1405 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099203.1 1551911 D 446462 CDS YP_003099204.1 256375544 8325586 complement(1552583..1553146) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bce:BC2347 acetyltransferase; GCN5-like N-acetyltransferase 1553146 8325586 Amir_1406 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003099204.1 1552583 R 446462 CDS YP_003099205.1 256375545 8325587 complement(1553143..1553646) 1 NC_013093.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: bur:Bcep18194_A6310 YbaK/prolyl-tRNA synthetase like protein; YbaK/prolyl-tRNA synthetase associated protein 1553646 8325587 Amir_1407 Actinosynnema mirum DSM 43827 YbaK/prolyl-tRNA synthetase associated protein YP_003099205.1 1553143 R 446462 CDS YP_003099206.1 256375546 8325588 1553938..1554774 1 NC_013093.1 PFAM: protein of unknown function DUF1503; hypothetical protein 1554774 8325588 Amir_1408 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099206.1 1553938 D 446462 CDS YP_003099207.1 256375547 8325589 complement(1554930..1556525) 1 NC_013093.1 KEGG: vsp:VS_1778 hypothetical protein; hypothetical protein 1556525 8325589 Amir_1409 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099207.1 1554930 R 446462 CDS YP_003099208.1 256375548 8325590 1556601..1557017 1 NC_013093.1 KEGG: rle:RL3033 hypothetical protein; hypothetical protein 1557017 8325590 Amir_1410 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099208.1 1556601 D 446462 CDS YP_003099209.1 256375549 8325591 1557326..1557964 1 NC_013093.1 PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; KEGG: gme:Gmet_0062 GntR family transcriptional regulator; GntR family transcriptional regulator 1557964 8325591 Amir_1411 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003099209.1 1557326 D 446462 CDS YP_003099210.1 256375550 8325592 1557966..1558961 1 NC_013093.1 catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate; 1-aminocyclopropane-1-carboxylate deaminase 1558961 8325592 Amir_1412 Actinosynnema mirum DSM 43827 1-aminocyclopropane-1-carboxylate deaminase YP_003099210.1 1557966 D 446462 CDS YP_003099211.1 256375551 8325593 complement(1559384..1564204) 1 NC_013093.1 PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; ATPase AAA; KEGG: scl:sce3970 ATP-dependent helicase; DEAD/H associated domain-containing protein 1564204 8325593 Amir_1413 Actinosynnema mirum DSM 43827 DEAD/H associated domain-containing protein YP_003099211.1 1559384 R 446462 CDS YP_003099212.1 256375552 8325594 complement(1564201..1564338) 1 NC_013093.1 hypothetical protein 1564338 8325594 Amir_1414 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099212.1 1564201 R 446462 CDS YP_003099213.1 256375553 8325595 1564506..1566479 1 NC_013093.1 PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70; Heat shock protein 70 1566479 8325595 Amir_1415 Actinosynnema mirum DSM 43827 Heat shock protein 70 YP_003099213.1 1564506 D 446462 CDS YP_003099214.1 256375554 8325596 1566531..1567739 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bca:BCE_1913 major facilitator superfamily protein; major facilitator superfamily protein 1567739 8325596 Amir_1416 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099214.1 1566531 D 446462 CDS YP_003099215.1 256375555 8325597 complement(1567764..1567910) 1 NC_013093.1 hypothetical protein 1567910 8325597 Amir_1417 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099215.1 1567764 R 446462 CDS YP_003099216.1 256375556 8325598 1568054..1568248 1 NC_013093.1 hypothetical protein 1568248 8325598 Amir_1418 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099216.1 1568054 D 446462 CDS YP_003099217.1 256375557 8325599 1568424..1569467 1 NC_013093.1 KEGG: bha:BH2383 recombinase A; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: ATPase AAA; recA protein 1569467 8325599 Amir_1419 Actinosynnema mirum DSM 43827 recA protein YP_003099217.1 1568424 D 446462 CDS YP_003099218.1 256375558 8325600 1569572..1570075 1 NC_013093.1 PFAM: regulatory protein RecX; KEGG: scl:sce0207 hypothetical protein; regulatory protein RecX 1570075 8325600 Amir_1420 Actinosynnema mirum DSM 43827 regulatory protein RecX YP_003099218.1 1569572 D 446462 CDS YP_003099219.1 256375559 8325601 complement(1570515..1571207) 1 NC_013093.1 KEGG: bsu:BSU25740 hypothetical protein; hypothetical protein 1571207 8325601 Amir_1421 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099219.1 1570515 R 446462 CDS YP_003099220.1 256375560 8325602 complement(1571513..1572151) 1 NC_013093.1 KEGG: sil:SPO3031 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase/4- hydroxy-2-oxoglutarate aldolase 1572151 8325602 Amir_1422 Actinosynnema mirum DSM 43827 2-dehydro-3-deoxyphosphogluconate aldolase/4- hydroxy-2-oxoglutarate aldolase YP_003099220.1 1571513 R 446462 CDS YP_003099221.1 256375561 8325603 complement(1572148..1574019) 1 NC_013093.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1574019 8325603 Amir_1423 Actinosynnema mirum DSM 43827 phosphogluconate dehydratase YP_003099221.1 1572148 R 446462 CDS YP_003099222.1 256375562 8325604 1574245..1574538 1 NC_013093.1 hypothetical protein 1574538 8325604 Amir_1424 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099222.1 1574245 D 446462 CDS YP_003099223.1 256375563 8325605 1575022..1575783 1 NC_013093.1 KEGG: aba:Acid345_1383 integral membrane protein; integral membrane protein 1575783 8325605 Amir_1425 Actinosynnema mirum DSM 43827 integral membrane protein YP_003099223.1 1575022 D 446462 CDS YP_003099224.1 256375564 8325606 1575828..1577699 1 NC_013093.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1577699 sdhA 8325606 sdhA Actinosynnema mirum DSM 43827 succinate dehydrogenase flavoprotein subunit YP_003099224.1 1575828 D 446462 CDS YP_003099225.1 256375565 8325607 1577701..1578450 1 NC_013093.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; fumarate reductase iron-sulfur subunit 1578450 8325607 Amir_1427 Actinosynnema mirum DSM 43827 fumarate reductase iron-sulfur subunit YP_003099225.1 1577701 D 446462 CDS YP_003099226.1 256375566 8325608 complement(1578402..1579256) 1 NC_013093.1 PFAM: ADP-ribosylation/Crystallin J1; KEGG: predicted protein; K05521 ADP- ribosylglycohydrolase; ADP-ribosylation/Crystallin J1 1579256 8325608 Amir_1428 Actinosynnema mirum DSM 43827 ADP-ribosylation/Crystallin J1 YP_003099226.1 1578402 R 446462 CDS YP_003099227.1 256375567 8325609 complement(1579290..1579418) 1 NC_013093.1 hypothetical protein 1579418 8325609 Amir_1429 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099227.1 1579290 R 446462 CDS YP_003099228.1 256375568 8325611 complement(1580183..1583029) 1 NC_013093.1 catalyzes the reduction of ribonucleotides to deoxyribonucleotides; the rate-limiting step in dNTP synthesis; vitamin B12-dependent ribonucleotide reductase 1583029 8325611 Amir_1431 Actinosynnema mirum DSM 43827 vitamin B12-dependent ribonucleotide reductase YP_003099228.1 1580183 R 446462 CDS YP_003099229.1 256375569 8325612 complement(1583151..1583606) 1 NC_013093.1 PFAM: ATP-cone domain protein; KEGG: mxa:MXAN_4765 hypothetical protein; ATP-cone domain-containing protein 1583606 8325612 Amir_1432 Actinosynnema mirum DSM 43827 ATP-cone domain-containing protein YP_003099229.1 1583151 R 446462 CDS YP_003099230.1 256375570 8325613 complement(1584009..1584506) 1 NC_013093.1 PFAM: peptidoglycan-binding LysM; KEGG: bpa:BPP0017 hypothetical protein; peptidoglycan-binding LysM 1584506 8325613 Amir_1433 Actinosynnema mirum DSM 43827 peptidoglycan-binding LysM YP_003099230.1 1584009 R 446462 CDS YP_003099231.1 256375571 8325614 1584725..1585432 1 NC_013093.1 KEGG: bha:BH2356 LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24 and S26 domain protein; SOS-response transcriptional repressor, LexA 1585432 8325614 Amir_1434 Actinosynnema mirum DSM 43827 SOS-response transcriptional repressor, LexA YP_003099231.1 1584725 D 446462 CDS YP_003099232.1 256375572 8325615 complement(1585456..1586544) 1 NC_013093.1 KEGG: scl:sce0154 hypothetical protein; hypothetical protein 1586544 8325615 Amir_1435 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099232.1 1585456 R 446462 CDS YP_003099233.1 256375573 8325616 complement(1586571..1588013) 1 NC_013093.1 TIGRFAM: GTP-binding proten HflX; PFAM: GTP-binding protein HSR1-related; KEGG: GTP-binding family protein; K03665 GTP- binding protein HflX; GTP-binding proten HflX 1588013 8325616 Amir_1436 Actinosynnema mirum DSM 43827 GTP-binding proten HflX YP_003099233.1 1586571 R 446462 CDS YP_003099234.1 256375574 8325617 complement(1588056..1588544) 1 NC_013093.1 PFAM: regulatory protein ArsR; ArsR family transcriptional regulator 1588544 8325617 Amir_1437 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003099234.1 1588056 R 446462 CDS YP_003099235.1 256375575 8325618 1588653..1589903 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_2815 major facilitator transporter; major facilitator superfamily protein 1589903 8325618 Amir_1438 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099235.1 1588653 D 446462 CDS YP_003099236.1 256375576 8325619 complement(1589935..1590753) 1 NC_013093.1 KEGG: ade:Adeh_0570 diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; PFAM: diaminopimelate epimerase; diaminopimelate epimerase 1590753 8325619 Amir_1439 Actinosynnema mirum DSM 43827 diaminopimelate epimerase YP_003099236.1 1589935 R 446462 CDS YP_003099237.1 256375577 8325620 complement(1590764..1591666) 1 NC_013093.1 KEGG: bha:BH2366 tRNA delta(2)- isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; tRNA delta(2)-isopentenylpyrophosphate transferase 1591666 8325620 Amir_1440 Actinosynnema mirum DSM 43827 tRNA delta(2)-isopentenylpyrophosphate transferase YP_003099237.1 1590764 R 446462 CDS YP_003099238.1 256375578 8325621 complement(1591663..1592394) 1 NC_013093.1 KEGG: ade:Adeh_1392 flagellar biosynthesis/type III secretory pathway protein-like; hypothetical protein 1592394 8325621 Amir_1441 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099238.1 1591663 R 446462 CDS YP_003099239.1 256375579 8325622 1592558..1593904 1 NC_013093.1 PFAM: protein of unknown function DUF349; KEGG: pha:PSHAa1895 hypothetical protein; hypothetical protein 1593904 8325622 Amir_1442 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099239.1 1592558 D 446462 CDS YP_003099240.1 256375580 8325623 complement(1593983..1594534) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1594534 8325623 Amir_1443 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099240.1 1593983 R 446462 CDS YP_003099241.1 256375581 8325624 complement(1594531..1596006) 1 NC_013093.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1596006 8325624 Amir_1444 Actinosynnema mirum DSM 43827 (dimethylallyl)adenosine tRNA methylthiotransferase YP_003099241.1 1594531 R 446462 CDS YP_003099242.1 256375582 8325625 1596358..1597281 1 NC_013093.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: tmz:Tmz1t_0431 TRAP transporter solute receptor, TAXI family; TRAP transporter solute receptor, TAXI family 1597281 8325625 Amir_1445 Actinosynnema mirum DSM 43827 TRAP transporter solute receptor, TAXI family YP_003099242.1 1596358 D 446462 CDS YP_003099243.1 256375583 8325626 complement(1597325..1598710) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pfl:PFL_3853 sensor histidine kinase; histidine kinase 1598710 8325626 Amir_1446 Actinosynnema mirum DSM 43827 histidine kinase YP_003099243.1 1597325 R 446462 CDS YP_003099244.1 256375584 8325627 complement(1598711..1599379) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: tbd:Tbd_2791 two component transcriptional regulator; winged helix family two component transcriptional regulator 1599379 8325627 Amir_1447 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003099244.1 1598711 R 446462 CDS YP_003099245.1 256375585 8325628 1599516..1600271 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pde:Pden_5082 ABC transporter; ABC transporter 1600271 8325628 Amir_1448 Actinosynnema mirum DSM 43827 ABC transporter YP_003099245.1 1599516 D 446462 CDS YP_003099246.1 256375586 8325629 1600339..1601226 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bce:BC0640 glutamine-binding protein; family 3 extracellular solute-binding protein 1601226 8325629 Amir_1449 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003099246.1 1600339 D 446462 CDS YP_003099247.1 256375587 8325630 1601309..1601956 1 NC_013093.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bca:BCE_0709 amino acid ABC transporter, permease protein; polar amino acid ABC transporter, inner membrane subunit 1601956 8325630 Amir_1450 Actinosynnema mirum DSM 43827 polar amino acid ABC transporter, inner membrane subunit YP_003099247.1 1601309 D 446462 CDS YP_003099248.1 256375588 8325631 1601953..1602825 1 NC_013093.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: aav:Aave_3754 polar amino acid ABC transporter, inner membrane subunit; polar amino acid ABC transporter, inner membrane subunit 1602825 8325631 Amir_1451 Actinosynnema mirum DSM 43827 polar amino acid ABC transporter, inner membrane subunit YP_003099248.1 1601953 D 446462 CDS YP_003099249.1 256375589 8325632 1602925..1603734 1 NC_013093.1 KEGG: psb:Psyr_0113 hypothetical protein; hypothetical protein 1603734 8325632 Amir_1452 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099249.1 1602925 D 446462 CDS YP_003099250.1 256375590 8325633 1603952..1604146 1 NC_013093.1 hypothetical protein 1604146 8325633 Amir_1453 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099250.1 1603952 D 446462 CDS YP_003099251.1 256375591 8325634 complement(1604497..1605021) 1 NC_013093.1 PFAM: protein of unknown function DUF1470; KEGG: xau:Xaut_0954 hypothetical protein; hypothetical protein 1605021 8325634 Amir_1454 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099251.1 1604497 R 446462 CDS YP_003099252.1 256375592 8325635 1605108..1605767 1 NC_013093.1 KEGG: pde:Pden_0168 hypothetical protein; hypothetical protein 1605767 8325635 Amir_1455 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099252.1 1605108 D 446462 CDS YP_003099253.1 256375593 8325636 1605798..1606733 1 NC_013093.1 KEGG: sus:Acid_4767 hypothetical protein; hypothetical protein 1606733 8325636 Amir_1456 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099253.1 1605798 D 446462 CDS YP_003099254.1 256375594 8325637 1606759..1607457 1 NC_013093.1 PFAM: endonuclease V; KEGG: sde:Sde_3689 endonuclease V; deoxyribonuclease V 1607457 8325637 Amir_1457 Actinosynnema mirum DSM 43827 deoxyribonuclease V YP_003099254.1 1606759 D 446462 CDS YP_003099255.1 256375595 8325638 complement(1607462..1608694) 1 NC_013093.1 PFAM: glycoside hydrolase family 4; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: sus:Acid_1925 glycoside hydrolase family protein; glycoside hydrolase family protein 1608694 8325638 Amir_1458 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003099255.1 1607462 R 446462 CDS YP_003099256.1 256375596 8325639 complement(1608714..1609712) 1 NC_013093.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1609712 8325639 Amir_1459 Actinosynnema mirum DSM 43827 adenosine deaminase YP_003099256.1 1608714 R 446462 CDS YP_003099257.1 256375597 8325640 1609839..1611662 1 NC_013093.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1611662 8325640 Amir_1460 Actinosynnema mirum DSM 43827 x-prolyl-dipeptidyl aminopeptidase YP_003099257.1 1609839 D 446462 CDS YP_003099258.1 256375598 8325641 1611816..1612826 1 NC_013093.1 KEGG: afw:Anae109_2566 H+transporting two-sector ATPase C (AC39) subunit; hypothetical protein 1612826 8325641 Amir_1461 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099258.1 1611816 D 446462 CDS YP_003099259.1 256375599 8325642 complement(1613008..1615050) 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: ade:Adeh_0114 peptidase S9, prolyl oligopeptidase; peptidase S9 prolyl oligopeptidase active site domain-containing protein 1615050 8325642 Amir_1462 Actinosynnema mirum DSM 43827 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_003099259.1 1613008 R 446462 CDS YP_003099260.1 256375600 8325643 complement(1615056..1616018) 1 NC_013093.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; dTDP-4- dehydrorhamnose reductase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; KEGG: bha:BH1108 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 1616018 8325643 Amir_1463 Actinosynnema mirum DSM 43827 UDP-glucose 4-epimerase YP_003099260.1 1615056 R 446462 CDS YP_003099261.1 256375601 8325644 complement(1617156..1618340) 1 NC_013093.1 TIGRFAM: galactokinase; PFAM: GHMP kinase domain protein; GHMP kinase; KEGG: scl:sce2225 hypothetical protein; galactokinase 1618340 8325644 Amir_1464 Actinosynnema mirum DSM 43827 galactokinase YP_003099261.1 1617156 R 446462 CDS YP_003099262.1 256375602 8325645 complement(1618346..1619038) 1 NC_013093.1 PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; KEGG: sus:Acid_2178 DtxR family iron dependent repressor; iron (metal) dependent repressor, DtxR family 1619038 8325645 Amir_1465 Actinosynnema mirum DSM 43827 iron (metal) dependent repressor, DtxR family YP_003099262.1 1618346 R 446462 CDS YP_003099263.1 256375603 8325646 1619136..1619984 1 NC_013093.1 PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: tbd:Tbd_2489 3-mercaptopyruvate sulfurtransferase; rhodanese domain-containing protein 1619984 8325646 Amir_1466 Actinosynnema mirum DSM 43827 rhodanese domain-containing protein YP_003099263.1 1619136 D 446462 CDS YP_003099264.1 256375604 8325647 complement(1620356..1620988) 1 NC_013093.1 KEGG: scl:sce4324 hypothetical protein; hypothetical protein 1620988 8325647 Amir_1467 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099264.1 1620356 R 446462 CDS YP_003099265.1 256375605 8325648 1621190..1622383 1 NC_013093.1 PFAM: histone deacetylase superfamily; KEGG: bha:BH3237 acetoin dehydrogenase; histone deacetylase superfamily 1622383 8325648 Amir_1468 Actinosynnema mirum DSM 43827 histone deacetylase superfamily YP_003099265.1 1621190 D 446462 CDS YP_003099266.1 256375606 8325649 1622383..1625091 1 NC_013093.1 PFAM: CoA-binding domain protein; GCN5-related N- acetyltransferase; KEGG: mgm:Mmc1_1098 CoA-binding domain protein; CoA-binding domain-containing protein 1625091 8325649 Amir_1469 Actinosynnema mirum DSM 43827 CoA-binding domain-containing protein YP_003099266.1 1622383 D 446462 CDS YP_003099267.1 256375607 8325650 1625368..1626192 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: bsu:BSU27440 glutamine ABC transporter (glutamine-binding protein); family 3 extracellular solute-binding protein 1626192 8325650 Amir_1470 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003099267.1 1625368 D 446462 CDS YP_003099268.1 256375608 8325651 1626252..1627025 1 NC_013093.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bha:BH3323 GntR family transcriptional regulator; GntR family transcriptional regulator 1627025 8325651 Amir_1471 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003099268.1 1626252 D 446462 CDS YP_003099269.1 256375609 8325652 1627273..1627623 1 NC_013093.1 hypothetical protein 1627623 8325652 Amir_1472 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099269.1 1627273 D 446462 CDS YP_003099270.1 256375610 8325653 complement(1627903..1628613) 1 NC_013093.1 KEGG: aba:Acid345_3970 hypothetical protein; hypothetical protein 1628613 8325653 Amir_1473 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099270.1 1627903 R 446462 CDS YP_003099271.1 256375611 8325654 complement(1628610..1629170) 1 NC_013093.1 KEGG: gbm:Gbem_2014 secreted protein; hypothetical protein 1629170 8325654 Amir_1474 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099271.1 1628610 R 446462 CDS YP_003099272.1 256375612 8325655 complement(1629277..1630431) 1 NC_013093.1 PFAM: protein of unknown function UPF0027; KEGG: scl:sce1307 hypothetical protein; hypothetical protein 1630431 8325655 Amir_1475 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099272.1 1629277 R 446462 CDS YP_003099273.1 256375613 8325656 complement(1630517..1631320) 1 NC_013093.1 PFAM: ABC transporter; KEGG: aeh:Mlg_2716 ABC transporter; ABC transporter 1631320 8325656 Amir_1476 Actinosynnema mirum DSM 43827 ABC transporter YP_003099273.1 1630517 R 446462 CDS YP_003099274.1 256375614 8325657 complement(1631317..1632282) 1 NC_013093.1 KEGG: aeh:Mlg_2715 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; daunorubicin ABC transporter ATPase 1632282 8325657 Amir_1477 Actinosynnema mirum DSM 43827 daunorubicin ABC transporter ATPase YP_003099274.1 1631317 R 446462 CDS YP_003099275.1 256375615 8325658 1632374..1632802 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: smt:Smal_2582 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 1632802 8325658 Amir_1478 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003099275.1 1632374 D 446462 CDS YP_003099276.1 256375616 8325659 1632947..1633801 1 NC_013093.1 hypothetical protein 1633801 8325659 Amir_1479 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099276.1 1632947 D 446462 CDS YP_003099277.1 256375617 8325660 1633798..1633977 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 1633977 8325660 Amir_1480 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099277.1 1633798 D 446462 CDS YP_003099278.1 256375618 8325661 complement(1634388..1635326) 1 NC_013093.1 KEGG: ade:Adeh_2732 heat repeat-containing PBS lyase; hypothetical protein 1635326 8325661 Amir_1481 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099278.1 1634388 R 446462 CDS YP_003099279.1 256375619 8325662 complement(1635407..1636330) 1 NC_013093.1 hypothetical protein 1636330 8325662 Amir_1482 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099279.1 1635407 R 446462 CDS YP_003099280.1 256375620 8325663 complement(1637021..1638931) 1 NC_013093.1 KEGG: ade:Adeh_1681 PE-PGRS family protein; signal transduction protein with Nacht domain 1638931 8325663 Amir_1483 Actinosynnema mirum DSM 43827 signal transduction protein with Nacht domain YP_003099280.1 1637021 R 446462 CDS YP_003099281.1 256375621 8325664 complement(1639091..1640584) 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: ppw:PputW619_1998 aldehyde dehydrogenase; aldehyde dehydrogenase 1640584 8325664 Amir_1484 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003099281.1 1639091 R 446462 CDS YP_003099282.1 256375622 8325665 complement(1640581..1641405) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short- chain dehydrogenase/reductase SDR; KEGG: pst:PSPTO_1053 hypothetical protein; NAD-dependent epimerase/dehydratase 1641405 8325665 Amir_1485 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003099282.1 1640581 R 446462 CDS YP_003099283.1 256375623 8325666 complement(1641430..1642212) 1 NC_013093.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: bpt:Bpet4676 IclR family transcriptional regulator; IclR family transcriptional regulator 1642212 8325666 Amir_1486 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003099283.1 1641430 R 446462 CDS YP_003099284.1 256375624 8325667 1642464..1643456 1 NC_013093.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 1643456 8325667 Amir_1487 Actinosynnema mirum DSM 43827 5-dehydro-4-deoxyglucarate dehydratase YP_003099284.1 1642464 D 446462 CDS YP_003099285.1 256375625 8325668 1643453..1644709 1 NC_013093.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: hypothetical protein; K01706 glucarate dehydratase; mandelate racemase/muconate lactonizing protein 1644709 8325668 Amir_1488 Actinosynnema mirum DSM 43827 mandelate racemase/muconate lactonizing protein YP_003099285.1 1643453 D 446462 CDS YP_003099286.1 256375626 8325669 1644703..1645836 1 NC_013093.1 KEGG: rle:pRL100423 hypothetical protein; hypothetical protein 1645836 8325669 Amir_1489 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099286.1 1644703 D 446462 CDS YP_003099287.1 256375627 8325670 1645887..1646390 1 NC_013093.1 hypothetical protein 1646390 8325670 Amir_1490 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099287.1 1645887 D 446462 CDS YP_003099288.1 256375628 8325671 1646491..1647039 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1647039 8325671 Amir_1491 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099288.1 1646491 D 446462 CDS YP_003099289.1 256375629 8325672 complement(1647116..1648780) 1 NC_013093.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: mxa:MXAN_3162 fumarate hydratase, class I; hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta 1648780 8325672 Amir_1492 Actinosynnema mirum DSM 43827 hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta YP_003099289.1 1647116 R 446462 CDS YP_003099290.1 256375630 8325673 complement(1649131..1650123) 1 NC_013093.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase; RNA polymerase sigma factor SigB 1650123 8325673 Amir_1493 Actinosynnema mirum DSM 43827 RNA polymerase sigma factor SigB YP_003099290.1 1649131 R 446462 CDS YP_003099291.1 256375631 8325674 complement(1650344..1650769) 1 NC_013093.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1650769 8325674 Amir_1494 Actinosynnema mirum DSM 43827 D-tyrosyl-tRNA(Tyr) deacylase YP_003099291.1 1650344 R 446462 CDS YP_003099292.1 256375632 8325675 complement(1650766..1652262) 1 NC_013093.1 PFAM: methyltransferase small; KEGG: sus:Acid_0229 methyltransferase small; methyltransferase small 1652262 8325675 Amir_1495 Actinosynnema mirum DSM 43827 methyltransferase small YP_003099292.1 1650766 R 446462 CDS YP_003099293.1 256375633 8325676 complement(1652363..1653871) 1 NC_013093.1 KEGG: bha:BH1072 hypothetical protein; PucR family transcriptional regulator 1653871 8325676 Amir_1496 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003099293.1 1652363 R 446462 CDS YP_003099294.1 256375634 8325677 1653949..1654269 1 NC_013093.1 hypothetical protein 1654269 8325677 Amir_1497 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099294.1 1653949 D 446462 CDS YP_003099295.1 256375635 8325678 complement(1654251..1655153) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: oan:Oant_2477 PfkB domain protein; PfkB domain-containing protein 1655153 8325678 Amir_1498 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003099295.1 1654251 R 446462 CDS YP_003099296.1 256375636 8325679 complement(1655150..1656058) 1 NC_013093.1 PFAM: Indigoidine synthase A family protein; KEGG: swd:Swoo_1446 indigoidine synthase A family protein; Indigoidine synthase A family protein 1656058 8325679 Amir_1499 Actinosynnema mirum DSM 43827 Indigoidine synthase A family protein YP_003099296.1 1655150 R 446462 CDS YP_003099297.1 256375637 8325680 1656090..1656335 1 NC_013093.1 hypothetical protein 1656335 8325680 Amir_1500 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099297.1 1656090 D 446462 CDS YP_003099298.1 256375638 8325681 complement(1656429..1657724) 1 NC_013093.1 PFAM: ribonuclease BN; KEGG: ppu:PP_4560 ribonuclease BN; ribonuclease BN 1657724 8325681 Amir_1501 Actinosynnema mirum DSM 43827 ribonuclease BN YP_003099298.1 1656429 R 446462 CDS YP_003099299.1 256375639 8325682 1657917..1659635 1 NC_013093.1 PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; KEGG: sde:Sde_1925 GGDEF family protein; type III restriction protein res subunit 1659635 8325682 Amir_1502 Actinosynnema mirum DSM 43827 type III restriction protein res subunit YP_003099299.1 1657917 D 446462 CDS YP_003099300.1 256375640 8325683 1660627..1661763 1 NC_013093.1 KEGG: scl:sce6008 xylose binding protein transport system; Monosaccharide-transporting ATPase 1661763 8325683 Amir_1503 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003099300.1 1660627 D 446462 CDS YP_003099301.1 256375641 8325684 1661861..1662634 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: acr:Acry_1972 ABC transporter; ABC transporter 1662634 8325684 Amir_1504 Actinosynnema mirum DSM 43827 ABC transporter YP_003099301.1 1661861 D 446462 CDS YP_003099302.1 256375642 8325685 1662634..1664124 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: xylH; ABC transporter membrane spanning protein (xylose); inner-membrane translocator 1664124 8325685 Amir_1505 Actinosynnema mirum DSM 43827 inner-membrane translocator YP_003099302.1 1662634 D 446462 CDS YP_003099303.1 256375643 8325686 1664126..1665298 1 NC_013093.1 PFAM: ROK family protein; KEGG: bha:BH2758 transcriptional repressor of the xylose operon; ROK family protein 1665298 8325686 Amir_1506 Actinosynnema mirum DSM 43827 ROK family protein YP_003099303.1 1664126 D 446462 CDS YP_003099304.1 256375644 8325687 complement(1665838..1666017) 1 NC_013093.1 hypothetical protein 1666017 8325687 Amir_1507 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099304.1 1665838 R 446462 CDS YP_003099305.1 256375645 8325688 1666546..1667103 1 NC_013093.1 KEGG: NACA, TEBP; nascent polypeptide-associated complex alpha subunit; hypothetical protein 1667103 8325688 Amir_1508 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099305.1 1666546 D 446462 CDS YP_003099306.1 256375646 8325689 complement(1667194..1668501) 1 NC_013093.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 1668501 8325689 Amir_1509 Actinosynnema mirum DSM 43827 RNA polymerase sigma factor YP_003099306.1 1667194 R 446462 CDS YP_003099307.1 256375647 8325690 complement(1668710..1669471) 1 NC_013093.1 PFAM: ROK family protein; KEGG: asa:ASA_3376 ROK family protein; polyphosphate--glucose phosphotransferase 1669471 8325690 Amir_1510 Actinosynnema mirum DSM 43827 polyphosphate--glucose phosphotransferase YP_003099307.1 1668710 R 446462 CDS YP_003099308.1 256375648 8325691 1669566..1670366 1 NC_013093.1 PFAM: inositol monophosphatase; KEGG: noc:Noc_0719 inositol-1(or 4)-monophosphatase; inositol-phosphate phosphatase 1670366 8325691 Amir_1511 Actinosynnema mirum DSM 43827 inositol-phosphate phosphatase YP_003099308.1 1669566 D 446462 CDS YP_003099309.1 256375649 8325692 complement(1670839..1671546) 1 NC_013093.1 hypothetical protein 1671546 8325692 Amir_1512 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099309.1 1670839 R 446462 CDS YP_003099310.1 256375650 8325693 1671965..1672264 1 NC_013093.1 hypothetical protein 1672264 8325693 Amir_1513 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099310.1 1671965 D 446462 CDS YP_003099311.1 256375651 8325694 complement(1672857..1673381) 1 NC_013093.1 hypothetical protein 1673381 8325694 Amir_1514 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099311.1 1672857 R 446462 CDS YP_003099312.1 256375652 8325695 1673421..1673888 1 NC_013093.1 KEGG: eli:ELI_10525 deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut 1673888 8325695 Amir_1515 Actinosynnema mirum DSM 43827 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut YP_003099312.1 1673421 D 446462 CDS YP_003099313.1 256375653 8325696 1673893..1674516 1 NC_013093.1 hypothetical protein 1674516 8325696 Amir_1516 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099313.1 1673893 D 446462 CDS YP_003099314.1 256375654 8325697 complement(1674570..1675340) 1 NC_013093.1 KEGG: mlo:mlr7232 hypothetical protein; hypothetical protein 1675340 8325697 Amir_1517 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099314.1 1674570 R 446462 CDS YP_003099315.1 256375655 8325698 1675453..1675830 1 NC_013093.1 PFAM: nucleic acid binding OB-fold tRNA/helicase- type; OB-fold tRNA/helicase-type nucleic acid binding protein 1675830 8325698 Amir_1518 Actinosynnema mirum DSM 43827 OB-fold tRNA/helicase-type nucleic acid binding protein YP_003099315.1 1675453 D 446462 CDS YP_003099316.1 256375656 8325699 1675827..1676645 1 NC_013093.1 hypothetical protein 1676645 8325699 Amir_1519 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099316.1 1675827 D 446462 CDS YP_003099317.1 256375657 8325700 complement(1676742..1677398) 1 NC_013093.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rru:Rru_A1681 potassium transporter peripheral membrane component; TrkA-N domain-containing protein 1677398 8325700 Amir_1520 Actinosynnema mirum DSM 43827 TrkA-N domain-containing protein YP_003099317.1 1676742 R 446462 CDS YP_003099318.1 256375658 8325701 complement(1677398..1678060) 1 NC_013093.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: asa:ASA_4143 potassium transporter peripheral membrane component; TrkA-N domain-containing protein 1678060 8325701 Amir_1521 Actinosynnema mirum DSM 43827 TrkA-N domain-containing protein YP_003099318.1 1677398 R 446462 CDS YP_003099319.1 256375659 8325702 1678144..1680168 1 NC_013093.1 KEGG: bcb:BCB4264_A1880 hypothetical protein; hypothetical protein 1680168 8325702 Amir_1522 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099319.1 1678144 D 446462 CDS YP_003099320.1 256375660 8325703 1680165..1681400 1 NC_013093.1 PFAM: deoxyribonuclease/rho motif-related TRAM; (uracil-5)-methyltransferase; KEGG: sus:Acid_5841 23S rRNA (uracil-5-)- methyltransferase RumA; TRAM domain-containing protein 1681400 8325703 Amir_1523 Actinosynnema mirum DSM 43827 TRAM domain-containing protein YP_003099320.1 1680165 D 446462 CDS YP_003099321.1 256375661 8325704 1681489..1683390 1 NC_013093.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1683390 8325704 Amir_1524 Actinosynnema mirum DSM 43827 1-deoxy-D-xylulose-5-phosphate synthase YP_003099321.1 1681489 D 446462 CDS YP_003099322.1 256375662 8325705 1683607..1684311 1 NC_013093.1 PFAM: hypothetical protein; KEGG: bja:bll5629 hypothetical protein; hypothetical protein 1684311 8325705 Amir_1525 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099322.1 1683607 D 446462 CDS YP_003099323.1 256375663 8325706 1684347..1685024 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: mca:MCA2330 DNA-binding response regulator; winged helix family two component transcriptional regulator 1685024 8325706 Amir_1526 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003099323.1 1684347 D 446462 CDS YP_003099324.1 256375664 8325707 1685125..1686156 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sfu:Sfum_2006 integral membrane sensor signal transduction histidine kinase; histidine kinase 1686156 8325707 Amir_1527 Actinosynnema mirum DSM 43827 histidine kinase YP_003099324.1 1685125 D 446462 CDS YP_003099325.1 256375665 8325712 complement(1691800..1691940) 1 NC_013093.1 hypothetical protein 1691940 8325712 Amir_1528 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099325.1 1691800 R 446462 CDS YP_003099326.1 256375666 8325713 complement(1692143..1692736) 1 NC_013093.1 KEGG: scl:sce7642 hypothetical protein; hypothetical protein 1692736 8325713 Amir_1529 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099326.1 1692143 R 446462 CDS YP_003099327.1 256375667 8325714 complement(1692780..1693151) 1 NC_013093.1 PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: azo:azo2136 hypothetical protein; MazG nucleotide pyrophosphohydrolase 1693151 8325714 Amir_1530 Actinosynnema mirum DSM 43827 MazG nucleotide pyrophosphohydrolase YP_003099327.1 1692780 R 446462 CDS YP_003099328.1 256375668 8325715 complement(1693176..1693940) 1 NC_013093.1 hypothetical protein 1693940 8325715 Amir_1531 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099328.1 1693176 R 446462 CDS YP_003099329.1 256375669 8325716 complement(1693937..1695190) 1 NC_013093.1 KEGG: nha:Nham_3622 OmpA/MotB; hypothetical protein 1695190 8325716 Amir_1532 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099329.1 1693937 R 446462 CDS YP_003099330.1 256375670 8325717 complement(1695187..1695621) 1 NC_013093.1 hypothetical protein 1695621 8325717 Amir_1533 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099330.1 1695187 R 446462 CDS YP_003099331.1 256375671 8325718 complement(1695875..1696231) 1 NC_013093.1 hypothetical protein 1696231 8325718 Amir_1534 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099331.1 1695875 R 446462 CDS YP_003099332.1 256375672 8325719 complement(1696432..1696773) 1 NC_013093.1 hypothetical protein 1696773 8325719 Amir_1535 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099332.1 1696432 R 446462 CDS YP_003099333.1 256375673 8325721 1697273..1697959 1 NC_013093.1 KEGG: vvy:VV1763 hypothetical protein; hypothetical protein 1697959 8325721 Amir_1537 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099333.1 1697273 D 446462 CDS YP_003099334.1 256375674 8325722 complement(1698000..1698764) 1 NC_013093.1 PFAM: protein of unknown function DUF72; KEGG: xac:XAC2920 hypothetical protein; hypothetical protein 1698764 8325722 Amir_1538 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099334.1 1698000 R 446462 CDS YP_003099335.1 256375675 8325723 1698813..1699097 1 NC_013093.1 TIGRFAM: prevent-host-death family protein; KEGG: rlt:Rleg2_2735 prevent-host-death family protein; prevent-host-death family protein 1699097 8325723 Amir_1539 Actinosynnema mirum DSM 43827 prevent-host-death family protein YP_003099335.1 1698813 D 446462 CDS YP_003099336.1 256375676 8325724 1699085..1699498 1 NC_013093.1 PFAM: PilT protein domain protein; KEGG: bcm:Bcenmc03_4257 PilT domain-containing protein; PilT protein domain-containing protein 1699498 8325724 Amir_1540 Actinosynnema mirum DSM 43827 PilT protein domain-containing protein YP_003099336.1 1699085 D 446462 CDS YP_003099337.1 256375677 8325725 complement(1699569..1699970) 1 NC_013093.1 hypothetical protein 1699970 8325725 Amir_1541 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099337.1 1699569 R 446462 CDS YP_003099338.1 256375678 8325726 complement(1700115..1701017) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: ank:AnaeK_0030 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 1701017 8325726 Amir_1542 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003099338.1 1700115 R 446462 CDS YP_003099339.1 256375679 8325727 complement(1701157..1703268) 1 NC_013093.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: sfu:Sfum_1404 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase 1703268 8325727 Amir_1543 Actinosynnema mirum DSM 43827 3-hydroxyacyl-CoA dehydrogenase YP_003099339.1 1701157 R 446462 CDS YP_003099340.1 256375680 8325728 complement(1703265..1704485) 1 NC_013093.1 KEGG: sfu:Sfum_1403 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase 1704485 8325728 Amir_1544 Actinosynnema mirum DSM 43827 acetyl-CoA acetyltransferase YP_003099340.1 1703265 R 446462 CDS YP_003099341.1 256375681 8325729 complement(1704572..1705021) 1 NC_013093.1 KEGG: scl:sce6782 hypothetical protein; hypothetical protein 1705021 8325729 Amir_1545 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099341.1 1704572 R 446462 CDS YP_003099342.1 256375682 8325730 complement(1705018..1705938) 1 NC_013093.1 KEGG: scl:sce6783 hypothetical protein; hypothetical protein 1705938 8325730 Amir_1546 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099342.1 1705018 R 446462 CDS YP_003099343.1 256375683 8325731 1706023..1706742 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: smt:Smal_2399 transcriptional regulator, MerR family; MerR family transcriptional regulator 1706742 8325731 Amir_1547 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003099343.1 1706023 D 446462 CDS YP_003099344.1 256375684 8325732 complement(1707050..1708294) 1 NC_013093.1 PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein; KEGG: ade:Adeh_1602 3'-5' exonuclease; 3'-5' exonuclease 1708294 8325732 Amir_1548 Actinosynnema mirum DSM 43827 3'-5' exonuclease YP_003099344.1 1707050 R 446462 CDS YP_003099345.1 256375685 8325733 complement(1708365..1709081) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: mfa:Mfla_0447 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 1709081 8325733 Amir_1549 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099345.1 1708365 R 446462 CDS YP_003099346.1 256375686 8325734 1709337..1710503 1 NC_013093.1 PFAM: peptidase M19 renal dipeptidase; KEGG: eli:ELI_09665 dipeptidase; membrane dipeptidase 1710503 8325734 Amir_1550 Actinosynnema mirum DSM 43827 membrane dipeptidase YP_003099346.1 1709337 D 446462 CDS YP_003099347.1 256375687 8325735 complement(1710712..1711260) 1 NC_013093.1 hypothetical protein 1711260 8325735 Amir_1551 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099347.1 1710712 R 446462 CDS YP_003099348.1 256375688 8325736 1711422..1712474 1 NC_013093.1 KEGG: scl:sce8628 uroporphyrinogen decarboxylase; TIGRFAM: uroporphyrinogen decarboxylase; PFAM: uroporphyrinogen decarboxylase (URO-D); uroporphyrinogen decarboxylase 1712474 8325736 Amir_1552 Actinosynnema mirum DSM 43827 uroporphyrinogen decarboxylase YP_003099348.1 1711422 D 446462 CDS YP_003099349.1 256375689 8325737 1712471..1713892 1 NC_013093.1 KEGG: aba:Acid345_0695 protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; protoporphyrinogen oxidase 1713892 8325737 Amir_1553 Actinosynnema mirum DSM 43827 protoporphyrinogen oxidase YP_003099349.1 1712471 D 446462 CDS YP_003099350.1 256375690 8325738 1713919..1714617 1 NC_013093.1 PFAM: Chlorite dismutase; KEGG: bha:BH3825 heme peroxidase; Chlorite dismutase 1714617 8325738 Amir_1554 Actinosynnema mirum DSM 43827 Chlorite dismutase YP_003099350.1 1713919 D 446462 CDS YP_003099351.1 256375691 8325739 complement(1714673..1717909) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: shn:Shewana3_1740 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 1717909 8325739 Amir_1555 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003099351.1 1714673 R 446462 CDS YP_003099352.1 256375692 8325741 complement(1721459..1721944) 1 NC_013093.1 hypothetical protein 1721944 8325741 Amir_1557 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099352.1 1721459 R 446462 CDS YP_003099353.1 256375693 8325742 complement(1722016..1722375) 1 NC_013093.1 hypothetical protein 1722375 8325742 Amir_1558 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099353.1 1722016 R 446462 CDS YP_003099354.1 256375694 8325743 complement(1722372..1723172) 1 NC_013093.1 PFAM: protein of unknown function DUF692; xylose isomerase; KEGG: scl:sce1885 hypothetical protein; hypothetical protein 1723172 8325743 Amir_1559 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099354.1 1722372 R 446462 CDS YP_003099355.1 256375695 8325744 complement(1723198..1723977) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1723977 8325744 Amir_1560 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099355.1 1723198 R 446462 CDS YP_003099356.1 256375696 8325745 complement(1724008..1724307) 1 NC_013093.1 KEGG: scl:sce6895 hypothetical protein; hypothetical protein 1724307 8325745 Amir_1561 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099356.1 1724008 R 446462 CDS YP_003099357.1 256375697 8325746 complement(1724383..1725249) 1 NC_013093.1 KEGG: erythrocyte membrane protein 1 (PfEMP1); hypothetical protein 1725249 8325746 Amir_1562 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099357.1 1724383 R 446462 CDS YP_003099358.1 256375698 8325747 complement(1725221..1726132) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1726132 8325747 Amir_1563 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099358.1 1725221 R 446462 CDS YP_003099359.1 256375699 8325748 complement(1726173..1727093) 1 NC_013093.1 KEGG: met:M446_2019 hypothetical protein; hypothetical protein 1727093 8325748 Amir_1564 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099359.1 1726173 R 446462 CDS YP_003099360.1 256375700 8325749 complement(1727353..1727781) 1 NC_013093.1 TIGRFAM: methionine-R-sulfoxide reductase; PFAM: methionine sulfoxide reductase B; KEGG: methionine-R-sulfoxide reductase SelR; methionine-R-sulfoxide reductase 1727781 8325749 Amir_1565 Actinosynnema mirum DSM 43827 methionine-R-sulfoxide reductase YP_003099360.1 1727353 R 446462 CDS YP_003099361.1 256375701 8325750 complement(1727881..1728195) 1 NC_013093.1 hypothetical protein 1728195 8325750 Amir_1566 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099361.1 1727881 R 446462 CDS YP_003099362.1 256375702 8325751 complement(1728491..1729441) 1 NC_013093.1 PFAM: L-asparaginase II; KEGG: sil:SPO3349 L-asparaginase; L-asparaginase II 1729441 8325751 Amir_1567 Actinosynnema mirum DSM 43827 L-asparaginase II YP_003099362.1 1728491 R 446462 CDS YP_003099363.1 256375703 8325752 1729531..1730190 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pde:Pden_4617 transcriptional regulator, GntR family; GntR family transcriptional regulator 1730190 8325752 Amir_1568 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003099363.1 1729531 D 446462 CDS YP_003099364.1 256375704 8325753 complement(1730266..1731435) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bja:blr3304 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 1731435 8325753 Amir_1569 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003099364.1 1730266 R 446462 CDS YP_003099365.1 256375705 8325754 complement(1731465..1732616) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: gur:Gura_3313 acyl-CoA dehydrogenase domain- containing protein; acyl-CoA dehydrogenase domain-containing protein 1732616 8325754 Amir_1570 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003099365.1 1731465 R 446462 CDS YP_003099366.1 256375706 8325755 1732806..1733798 1 NC_013093.1 TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: afw:Anae109_2830 DNA primase small subunit; DNA polymerase LigD, polymerase domain-containing protein 1733798 8325755 Amir_1571 Actinosynnema mirum DSM 43827 DNA polymerase LigD, polymerase domain-containing protein YP_003099366.1 1732806 D 446462 CDS YP_003099367.1 256375707 8325756 1733839..1734201 1 NC_013093.1 hypothetical protein 1734201 8325756 Amir_1572 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099367.1 1733839 D 446462 CDS YP_003099368.1 256375708 8325757 complement(1734198..1735178) 1 NC_013093.1 hypothetical protein 1735178 8325757 Amir_1573 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099368.1 1734198 R 446462 CDS YP_003099369.1 256375709 8325758 1735571..1736074 1 NC_013093.1 KEGG: bpy:Bphyt_2395 haemagluttinin domain protein; hemaglutinin domain-containing protein 1736074 8325758 Amir_1574 Actinosynnema mirum DSM 43827 hemaglutinin domain-containing protein YP_003099369.1 1735571 D 446462 CDS YP_003099370.1 256375710 8325759 1736307..1736579 1 NC_013093.1 hypothetical protein 1736579 8325759 Amir_1575 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099370.1 1736307 D 446462 CDS YP_003099371.1 256375711 8325760 1736832..1737497 1 NC_013093.1 KEGG: mpt:Mpe_A1758 hypothetical protein; hypothetical protein 1737497 8325760 Amir_1576 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099371.1 1736832 D 446462 CDS YP_003099372.1 256375712 8325761 complement(1738018..1739562) 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: hypothetical protein; TAP domain-containing protein 1739562 8325761 Amir_1577 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003099372.1 1738018 R 446462 CDS YP_003099373.1 256375713 8325762 1739653..1740558 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mrd:Mrad2831_3085 hypothetical protein; hypothetical protein 1740558 8325762 Amir_1578 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099373.1 1739653 D 446462 CDS YP_003099374.1 256375714 8325763 complement(1740560..1741636) 1 NC_013093.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; ATP-dependent DNA ligase 1741636 ligC 8325763 ligC Actinosynnema mirum DSM 43827 ATP-dependent DNA ligase YP_003099374.1 1740560 R 446462 CDS YP_003099375.1 256375715 8325764 complement(1741688..1742476) 1 NC_013093.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: jan:Jann_3421 5-amino-6-(5- phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase; bifunctional deaminase-reductase domain-containing protein 1742476 8325764 Amir_1580 Actinosynnema mirum DSM 43827 bifunctional deaminase-reductase domain-containing protein YP_003099375.1 1741688 R 446462 CDS YP_003099376.1 256375716 8325765 1742475..1743482 1 NC_013093.1 PFAM: AFG1-family ATPase; KEGG: shn:Shewana3_0691 AFG1 family ATPase; AFG1-family ATPase 1743482 8325765 Amir_1581 Actinosynnema mirum DSM 43827 AFG1-family ATPase YP_003099376.1 1742475 D 446462 CDS YP_003099377.1 256375717 8325766 1743552..1743797 1 NC_013093.1 hypothetical protein 1743797 8325766 Amir_1582 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099377.1 1743552 D 446462 CDS YP_003099378.1 256375718 8325767 1743996..1745624 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ade:Adeh_0830 ABC transporter, duplicated ATPase subunits; ABC transporter 1745624 8325767 Amir_1583 Actinosynnema mirum DSM 43827 ABC transporter YP_003099378.1 1743996 D 446462 CDS YP_003099379.1 256375719 8325768 complement(1745714..1746532) 1 NC_013093.1 KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein 1746532 8325768 Amir_1584 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099379.1 1745714 R 446462 CDS YP_003099380.1 256375720 8325769 complement(1746582..1747619) 1 NC_013093.1 KEGG: sus:Acid_6335 hypothetical protein; hypothetical protein 1747619 8325769 Amir_1585 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099380.1 1746582 R 446462 CDS YP_003099381.1 256375721 8325770 1747848..1749077 1 NC_013093.1 TIGRFAM: ornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: gbe:GbCGDNIH1_1948 ornithine--oxo-acid transaminase; ornithine aminotransferase 1749077 8325770 Amir_1586 Actinosynnema mirum DSM 43827 ornithine aminotransferase YP_003099381.1 1747848 D 446462 CDS YP_003099382.1 256375722 8325771 1749176..1750561 1 NC_013093.1 KEGG: mrd:Mrad2831_2396 hypothetical protein; hypothetical protein 1750561 8325771 Amir_1587 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099382.1 1749176 D 446462 CDS YP_003099383.1 256375723 8325772 1750591..1751295 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: xca:xccb100_3271 hypothetical protein; phosphoglycerate mutase 1751295 8325772 Amir_1588 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003099383.1 1750591 D 446462 CDS YP_003099384.1 256375724 8325773 1751353..1752153 1 NC_013093.1 KEGG: mxa:MXAN_0652 hypothetical protein; hypothetical protein 1752153 8325773 Amir_1589 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099384.1 1751353 D 446462 CDS YP_003099385.1 256375725 8325774 1752137..1752538 1 NC_013093.1 KEGG: ank:AnaeK_1723 hypothetical protein; hypothetical protein 1752538 8325774 Amir_1590 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099385.1 1752137 D 446462 CDS YP_003099386.1 256375726 8325775 1752618..1753628 1 NC_013093.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bcz:BCZK4892 LytR family transcriptional regulator; cell envelope-related transcriptional attenuator 1753628 8325775 Amir_1591 Actinosynnema mirum DSM 43827 cell envelope-related transcriptional attenuator YP_003099386.1 1752618 D 446462 CDS YP_003099387.1 256375727 8325776 complement(1753797..1754012) 1 NC_013093.1 hypothetical protein 1754012 8325776 Amir_1592 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099387.1 1753797 R 446462 CDS YP_003099388.1 256375728 8325777 1754516..1756726 1 NC_013093.1 PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: hypothetical protein; PA-phosphatase-like phosphodiesterase 1756726 8325777 Amir_1593 Actinosynnema mirum DSM 43827 PA-phosphatase-like phosphodiesterase YP_003099388.1 1754516 D 446462 CDS YP_003099389.1 256375729 8325778 1757344..1757625 1 NC_013093.1 hypothetical protein 1757625 8325778 Amir_1594 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099389.1 1757344 D 446462 CDS YP_003099390.1 256375730 8325779 complement(1757786..1760104) 1 NC_013093.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1760104 8325779 Amir_1595 Actinosynnema mirum DSM 43827 preprotein translocase subunit SecA YP_003099390.1 1757786 R 446462 CDS YP_003099391.1 256375731 8325780 complement(1760580..1760969) 1 NC_013093.1 KEGG: cak:Caul_3403 hypothetical protein; hypothetical protein 1760969 8325780 Amir_1596 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099391.1 1760580 R 446462 CDS YP_003099392.1 256375732 8325781 1761088..1761873 1 NC_013093.1 PFAM: SpoOM family protein; Arrestin-like-like; KEGG: shm:Shewmr7_2729 SpoOM family protein; SpoOM family protein 1761873 8325781 Amir_1597 Actinosynnema mirum DSM 43827 SpoOM family protein YP_003099392.1 1761088 D 446462 CDS YP_003099393.1 256375733 8325782 1762055..1763200 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: pfo:Pfl01_4696 acyl-CoA dehydrogenase-like; acyl-CoA dehydrogenase domain-containing protein 1763200 8325782 Amir_1598 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003099393.1 1762055 D 446462 CDS YP_003099394.1 256375734 8325783 1763290..1764486 1 NC_013093.1 KEGG: dac:Daci_0764 hypothetical protein; hypothetical protein 1764486 8325783 Amir_1599 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099394.1 1763290 D 446462 CDS YP_003099395.1 256375735 8325784 1764483..1765928 1 NC_013093.1 PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: dac:Daci_0766 von Willebrand factor type A; von Willebrand factor type A 1765928 8325784 Amir_1600 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003099395.1 1764483 D 446462 CDS YP_003099396.1 256375736 8325785 1765915..1766673 1 NC_013093.1 hypothetical protein 1766673 8325785 Amir_1601 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099396.1 1765915 D 446462 CDS YP_003099397.1 256375737 8325786 1766670..1767212 1 NC_013093.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: scl:sce4229 exonuclease; exonuclease RNase T and DNA polymerase III 1767212 8325786 Amir_1602 Actinosynnema mirum DSM 43827 exonuclease RNase T and DNA polymerase III YP_003099397.1 1766670 D 446462 CDS YP_003099398.1 256375738 8325787 1767241..1767810 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bph:Bphy_4824 TetR family transcriptional regulator; TetR family transcriptional regulator 1767810 8325787 Amir_1603 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099398.1 1767241 D 446462 CDS YP_003099399.1 256375739 8325788 complement(1767873..1768445) 1 NC_013093.1 hypothetical protein 1768445 8325788 Amir_1604 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099399.1 1767873 R 446462 CDS YP_003099400.1 256375740 8325789 complement(1768442..1768816) 1 NC_013093.1 hypothetical protein 1768816 8325789 Amir_1605 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099400.1 1768442 R 446462 CDS YP_003099401.1 256375741 8325790 complement(1768937..1769398) 1 NC_013093.1 PFAM: MaoC domain protein dehydratase; KEGG: pol:Bpro_1240 MaoC-like dehydratase; MaoC domain-containing protein dehydratase 1769398 8325790 Amir_1606 Actinosynnema mirum DSM 43827 MaoC domain-containing protein dehydratase YP_003099401.1 1768937 R 446462 CDS YP_003099402.1 256375742 8325791 complement(1769398..1770153) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bbr:BB0613 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 1770153 8325791 Amir_1607 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003099402.1 1769398 R 446462 CDS YP_003099403.1 256375743 8325792 1770497..1771309 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pau:PA14_43180 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 1771309 8325792 Amir_1608 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003099403.1 1770497 D 446462 CDS YP_003099404.1 256375744 8325793 1771309..1772265 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: qor; quinone oxidoreductase protein; alcohol dehydrogenase zinc-binding domain-containing protein 1772265 8325793 Amir_1609 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003099404.1 1771309 D 446462 CDS YP_003099405.1 256375745 8325794 complement(1772428..1772907) 1 NC_013093.1 KEGG: mucin-associated surface protein (MASP); mucin-associated surface protein 1772907 8325794 Amir_1610 Actinosynnema mirum DSM 43827 mucin-associated surface protein YP_003099405.1 1772428 R 446462 CDS YP_003099406.1 256375746 8325795 complement(1773139..1774347) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: mno:Mnod_8803 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 1774347 8325795 Amir_1611 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003099406.1 1773139 R 446462 CDS YP_003099407.1 256375747 8325796 complement(1774464..1775645) 1 NC_013093.1 PFAM: sodium/hydrogen exchanger; KEGG: bcb:BCB4264_A4853 sodium/hydrogen exchanger family protein; sodium/hydrogen exchanger 1775645 8325796 Amir_1612 Actinosynnema mirum DSM 43827 sodium/hydrogen exchanger YP_003099407.1 1774464 R 446462 CDS YP_003099408.1 256375748 8325797 complement(1775651..1776133) 1 NC_013093.1 PFAM: TrkA-C domain protein; KEGG: bcz:BCZK4776 potassium channel, C-terminus; TrkA-C domain-containing protein 1776133 8325797 Amir_1613 Actinosynnema mirum DSM 43827 TrkA-C domain-containing protein YP_003099408.1 1775651 R 446462 CDS YP_003099409.1 256375749 8325798 1776789..1777508 1 NC_013093.1 KEGG: gur:Gura_1465 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; cytidylate kinase 1777508 8325798 Amir_1614 Actinosynnema mirum DSM 43827 cytidylate kinase YP_003099409.1 1776789 D 446462 CDS YP_003099410.1 256375750 8325799 1777505..1778272 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: bha:BH1635 hypothetical protein; phospholipid/glycerol acyltransferase 1778272 8325799 Amir_1615 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003099410.1 1777505 D 446462 CDS YP_003099411.1 256375751 8325800 1778269..1779684 1 NC_013093.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1779684 engA 8325800 engA Actinosynnema mirum DSM 43827 GTP-binding protein EngA YP_003099411.1 1778269 D 446462 CDS YP_003099412.1 256375752 8325801 1779726..1780370 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 1780370 8325801 Amir_1617 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099412.1 1779726 D 446462 CDS YP_003099413.1 256375753 8325802 1780367..1781476 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 1781476 8325802 Amir_1618 Actinosynnema mirum DSM 43827 histidine kinase YP_003099413.1 1780367 D 446462 CDS YP_003099414.1 256375754 8325804 1781757..1782734 1 NC_013093.1 PFAM: integrase family protein; KEGG: scl:sce4427 site-specific recombinase; integrase family protein 1782734 8325804 Amir_1619 Actinosynnema mirum DSM 43827 integrase family protein YP_003099414.1 1781757 D 446462 CDS YP_003099415.1 256375755 8325805 1782731..1783006 1 NC_013093.1 hypothetical protein 1783006 8325805 Amir_1620 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099415.1 1782731 D 446462 CDS YP_003099416.1 256375756 8325806 1783003..1783188 1 NC_013093.1 hypothetical protein 1783188 8325806 Amir_1621 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099416.1 1783003 D 446462 CDS YP_003099417.1 256375757 8325807 1783232..1783483 1 NC_013093.1 hypothetical protein 1783483 8325807 Amir_1622 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099417.1 1783232 D 446462 CDS YP_003099418.1 256375758 8325808 complement(1783476..1783676) 1 NC_013093.1 hypothetical protein 1783676 8325808 Amir_1623 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099418.1 1783476 R 446462 CDS YP_003099419.1 256375759 8325809 complement(1783747..1783950) 1 NC_013093.1 hypothetical protein 1783950 8325809 Amir_1624 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099419.1 1783747 R 446462 CDS YP_003099420.1 256375760 8325810 complement(1783947..1784186) 1 NC_013093.1 hypothetical protein 1784186 8325810 Amir_1625 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099420.1 1783947 R 446462 CDS YP_003099421.1 256375761 8325811 1784770..1785558 1 NC_013093.1 hypothetical protein 1785558 8325811 Amir_1626 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099421.1 1784770 D 446462 CDS YP_003099422.1 256375762 8325812 1785587..1785766 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 1785766 8325812 Amir_1627 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099422.1 1785587 D 446462 CDS YP_003099423.1 256375763 8325813 complement(1785822..1786766) 1 NC_013093.1 hypothetical protein 1786766 8325813 Amir_1628 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099423.1 1785822 R 446462 CDS YP_003099424.1 256375764 8325814 complement(1786791..1787978) 1 NC_013093.1 KEGG: bcr:BCAH187_A3991 phage minor structural protein, N-region; hypothetical protein 1787978 8325814 Amir_1629 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099424.1 1786791 R 446462 CDS YP_003099425.1 256375765 8325815 complement(1787948..1788832) 1 NC_013093.1 hypothetical protein 1788832 8325815 Amir_1630 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099425.1 1787948 R 446462 CDS YP_003099426.1 256375766 8325816 complement(1788825..1792739) 1 NC_013093.1 KEGG: mgm:Mmc1_2162 hypothetical protein; hypothetical protein 1792739 8325816 Amir_1631 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099426.1 1788825 R 446462 CDS YP_003099427.1 256375767 8325817 complement(1792764..1792922) 1 NC_013093.1 hypothetical protein 1792922 8325817 Amir_1632 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099427.1 1792764 R 446462 CDS YP_003099428.1 256375768 8325818 complement(1793009..1793488) 1 NC_013093.1 hypothetical protein 1793488 8325818 Amir_1633 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099428.1 1793009 R 446462 CDS YP_003099429.1 256375769 8325819 complement(1793501..1793971) 1 NC_013093.1 hypothetical protein 1793971 8325819 Amir_1634 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099429.1 1793501 R 446462 CDS YP_003099430.1 256375770 8325820 complement(1793968..1794432) 1 NC_013093.1 hypothetical protein 1794432 8325820 Amir_1635 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099430.1 1793968 R 446462 CDS YP_003099431.1 256375771 8325821 complement(1794429..1794779) 1 NC_013093.1 hypothetical protein 1794779 8325821 Amir_1636 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099431.1 1794429 R 446462 CDS YP_003099432.1 256375772 8325822 complement(1794779..1795099) 1 NC_013093.1 hypothetical protein 1795099 8325822 Amir_1637 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099432.1 1794779 R 446462 CDS YP_003099433.1 256375773 8325823 complement(1795093..1795536) 1 NC_013093.1 KEGG: bpy:Bphyt_0835 hypothetical protein; hypothetical protein 1795536 8325823 Amir_1638 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099433.1 1795093 R 446462 CDS YP_003099434.1 256375774 8325824 complement(1795533..1797497) 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: similar to hCG2041257; G-D-S-L family lipolytic protein 1797497 8325824 Amir_1639 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003099434.1 1795533 R 446462 CDS YP_003099435.1 256375775 8325825 complement(1797501..1797680) 1 NC_013093.1 hypothetical protein 1797680 8325825 Amir_1640 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099435.1 1797501 R 446462 CDS YP_003099436.1 256375776 8325826 complement(1797677..1798336) 1 NC_013093.1 KEGG: mno:Mnod_2529 hypothetical protein; hypothetical protein 1798336 8325826 Amir_1641 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099436.1 1797677 R 446462 CDS YP_003099437.1 256375777 8325827 complement(1798360..1798722) 1 NC_013093.1 hypothetical protein 1798722 8325827 Amir_1642 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099437.1 1798360 R 446462 CDS YP_003099438.1 256375778 8325828 complement(1798715..1798969) 1 NC_013093.1 hypothetical protein 1798969 8325828 Amir_1643 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099438.1 1798715 R 446462 CDS YP_003099439.1 256375779 8325829 complement(1799059..1799370) 1 NC_013093.1 hypothetical protein 1799370 8325829 Amir_1644 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099439.1 1799059 R 446462 CDS YP_003099440.1 256375780 8325830 complement(1799372..1800592) 1 NC_013093.1 KEGG: bcr:BCAH187_A3735 hypothetical protein; hypothetical protein 1800592 8325830 Amir_1645 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099440.1 1799372 R 446462 CDS YP_003099441.1 256375781 8325831 complement(1800706..1801410) 1 NC_013093.1 KEGG: azc:AZC_1123 hypothetical protein; hypothetical protein 1801410 8325831 Amir_1646 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099441.1 1800706 R 446462 CDS YP_003099442.1 256375782 8325832 complement(1801435..1801707) 1 NC_013093.1 KEGG: nwi:Nwi_1556 hypothetical protein; hypothetical protein 1801707 8325832 Amir_1647 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099442.1 1801435 R 446462 CDS YP_003099443.1 256375783 8325833 complement(1801731..1801940) 1 NC_013093.1 hypothetical protein 1801940 8325833 Amir_1648 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099443.1 1801731 R 446462 CDS YP_003099444.1 256375784 8325834 1802067..1802546 1 NC_013093.1 hypothetical protein 1802546 8325834 Amir_1649 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099444.1 1802067 D 446462 CDS YP_003099445.1 256375785 8325835 complement(1802599..1803663) 1 NC_013093.1 KEGG: ade:Adeh_2705 response regulator receiver; hypothetical protein 1803663 8325835 Amir_1650 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099445.1 1802599 R 446462 CDS YP_003099446.1 256375786 8325836 complement(1803663..1805273) 1 NC_013093.1 hypothetical protein 1805273 8325836 Amir_1651 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099446.1 1803663 R 446462 CDS YP_003099447.1 256375787 8325837 1805405..1805812 1 NC_013093.1 hypothetical protein 1805812 8325837 Amir_1652 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099447.1 1805405 D 446462 CDS YP_003099448.1 256375788 8325838 complement(1805793..1807106) 1 NC_013093.1 TIGRFAM: phage terminase, large subunit, PBSX family; PFAM: protein of unknown function DUF264; phage terminase, large subunit, PBSX family 1807106 8325838 Amir_1653 Actinosynnema mirum DSM 43827 phage terminase, large subunit, PBSX family YP_003099448.1 1805793 R 446462 CDS YP_003099449.1 256375789 8325839 complement(1807103..1807738) 1 NC_013093.1 hypothetical protein 1807738 8325839 Amir_1654 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099449.1 1807103 R 446462 CDS YP_003099450.1 256375790 8325840 complement(1807990..1808364) 1 NC_013093.1 hypothetical protein 1808364 8325840 Amir_1655 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099450.1 1807990 R 446462 CDS YP_003099451.1 256375791 8325841 complement(1808361..1808660) 1 NC_013093.1 KEGG: seg:SG1189 predicted phage regulatory protein; hypothetical protein 1808660 8325841 Amir_1656 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099451.1 1808361 R 446462 CDS YP_003099452.1 256375792 8325842 complement(1808657..1809127) 1 NC_013093.1 hypothetical protein 1809127 8325842 Amir_1657 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099452.1 1808657 R 446462 CDS YP_003099453.1 256375793 8325843 complement(1809139..1810431) 1 NC_013093.1 KEGG: ade:Adeh_1681 PE-PGRS family protein; PE-PGRS family protein 1810431 8325843 Amir_1658 Actinosynnema mirum DSM 43827 PE-PGRS family protein YP_003099453.1 1809139 R 446462 CDS YP_003099454.1 256375794 8325844 1810785..1811369 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: dar:Daro_0963 NUDIX hydrolase; NUDIX hydrolase 1811369 8325844 Amir_1659 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003099454.1 1810785 D 446462 CDS YP_003099455.1 256375795 8325845 complement(1811836..1812789) 1 NC_013093.1 hypothetical protein 1812789 8325845 Amir_1660 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099455.1 1811836 R 446462 CDS YP_003099456.1 256375796 8325846 1813199..1813957 1 NC_013093.1 PFAM: MHYT domain protein; KEGG: sde:Sde_0524 integral membrane sensor protein; integral membrane sensor protein 1813957 8325846 Amir_1661 Actinosynnema mirum DSM 43827 integral membrane sensor protein YP_003099456.1 1813199 D 446462 CDS YP_003099457.1 256375797 8325847 1814020..1814577 1 NC_013093.1 PFAM: ribonuclease H; KEGG: bte:BTH_I2790 RNase H; ribonuclease H 1814577 8325847 Amir_1662 Actinosynnema mirum DSM 43827 ribonuclease H YP_003099457.1 1814020 D 446462 CDS YP_003099458.1 256375798 8325848 1814767..1815402 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 1815402 8325848 Amir_1663 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099458.1 1814767 D 446462 CDS YP_003099459.1 256375799 8325849 complement(1815524..1817614) 1 NC_013093.1 KEGG: bcj:BCAM2418 haemagglutinin-related autotransporter protein; hypothetical protein 1817614 8325849 Amir_1664 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099459.1 1815524 R 446462 CDS YP_003099460.1 256375800 8325850 complement(1817991..1819694) 1 NC_013093.1 KEGG: alpha-galactosidase, / melibiase, / alpha-D-galactoside galactohydrolase, ; K07407 alpha-galactosidase; PFAM: Ricin B lectin; glycoside hydrolase clan GH- D; SMART: Ricin B lectin; alpha-galactosidase 1819694 8325850 Amir_1665 Actinosynnema mirum DSM 43827 alpha-galactosidase YP_003099460.1 1817991 R 446462 CDS YP_003099461.1 256375801 8325851 1820073..1821461 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: scl:sce8759 hypothetical protein; XRE family transcriptional regulator 1821461 8325851 Amir_1666 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003099461.1 1820073 D 446462 CDS YP_003099462.1 256375802 8325852 complement(1821436..1821897) 1 NC_013093.1 hypothetical protein 1821897 8325852 Amir_1667 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099462.1 1821436 R 446462 CDS YP_003099463.1 256375803 8325853 1822290..1823048 1 NC_013093.1 KEGG: msl:Msil_3349 hypothetical protein; hypothetical protein 1823048 8325853 Amir_1668 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099463.1 1822290 D 446462 CDS YP_003099464.1 256375804 8325854 1823045..1824178 1 NC_013093.1 KEGG: mag:amb3212 periplasmic protein TonB, links inner and outer membranes; hypothetical protein 1824178 8325854 Amir_1669 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099464.1 1823045 D 446462 CDS YP_003099465.1 256375805 8325855 complement(1824222..1824917) 1 NC_013093.1 KEGG: rso:RSc2037 ABC transporter ATP-binding protein; TIGRFAM: urea ABC transporter, ATP-binding protein UrtE; PFAM: ABC transporter; SMART: ATPase AAA; urea ABC transporter ATP-binding protein UrtE 1824917 8325855 Amir_1670 Actinosynnema mirum DSM 43827 urea ABC transporter ATP-binding protein UrtE YP_003099465.1 1824222 R 446462 CDS YP_003099466.1 256375806 8325856 complement(1824917..1825663) 1 NC_013093.1 KEGG: scl:sce5582 ABC transporter ATP- binding protein; TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter; SMART: ATPase AAA; urea ABC transporter ATP-binding protein 1825663 8325856 Amir_1671 Actinosynnema mirum DSM 43827 urea ABC transporter ATP-binding protein YP_003099466.1 1824917 R 446462 CDS YP_003099467.1 256375807 8325857 complement(1825660..1826838) 1 NC_013093.1 TIGRFAM: urea ABC transporter, permease protein UrtC; PFAM: inner-membrane translocator; KEGG: scl:sce5581 branched-chain amino acid ABC transporter, permease protein; urea ABC transporter permease 1826838 8325857 Amir_1672 Actinosynnema mirum DSM 43827 urea ABC transporter permease YP_003099467.1 1825660 R 446462 CDS YP_003099468.1 256375808 8325858 complement(1826835..1827713) 1 NC_013093.1 TIGRFAM: urea ABC transporter, permease protein UrtB; PFAM: inner-membrane translocator; KEGG: scl:sce5580 branched-chain amino acid ABC transporter, permease protein; urea ABC transporter permease 1827713 8325858 Amir_1673 Actinosynnema mirum DSM 43827 urea ABC transporter permease YP_003099468.1 1826835 R 446462 CDS YP_003099469.1 256375809 8325859 complement(1827715..1828938) 1 NC_013093.1 TIGRFAM: urea ABC transporter, urea binding protein; PFAM: Extracellular ligand-binding receptor; KEGG: scl:sce5579 branched-chain amino acid transport system substrate-binding protein; urea ABC transporter, urea binding protein 1828938 8325859 Amir_1674 Actinosynnema mirum DSM 43827 urea ABC transporter, urea binding protein YP_003099469.1 1827715 R 446462 CDS YP_003099470.1 256375810 8325860 1829213..1830340 1 NC_013093.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: bha:BH0583 hypothetical protein; hypothetical protein 1830340 8325860 Amir_1675 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099470.1 1829213 D 446462 CDS YP_003099471.1 256375811 8325861 complement(1830337..1832283) 1 NC_013093.1 KEGG: sde:Sde_0054 adenylyl cyclase class- 3/4/guanylyl cyclase; adenylyl cyclase class-3/4/guanylyl cyclase 1832283 8325861 Amir_1676 Actinosynnema mirum DSM 43827 adenylyl cyclase class-3/4/guanylyl cyclase YP_003099471.1 1830337 R 446462 CDS YP_003099472.1 256375812 8325862 complement(1832382..1833689) 1 NC_013093.1 PFAM: ROK family protein; KEGG: rlt:Rleg2_2328 ROK family protein; ROK family protein 1833689 8325862 Amir_1677 Actinosynnema mirum DSM 43827 ROK family protein YP_003099472.1 1832382 R 446462 CDS YP_003099473.1 256375813 8325863 1833856..1835517 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: scl:sce8424 ABC-type dipeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 1835517 8325863 Amir_1678 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003099473.1 1833856 D 446462 CDS YP_003099474.1 256375814 8325864 1835514..1836557 1 NC_013093.1 KEGG: scl:sce4298 ABC-type oligopeptide transport system, ATPase component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 1836557 8325864 Amir_1679 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003099474.1 1835514 D 446462 CDS YP_003099475.1 256375815 8325865 1836554..1837534 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce4301 peptide ABC transporter, permease protein; ABC transporter inner membrane protein 1837534 8325865 Amir_1680 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099475.1 1836554 D 446462 CDS YP_003099476.1 256375816 8325866 1837538..1838614 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sit:TM1040_2743 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 1838614 8325866 Amir_1681 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099476.1 1837538 D 446462 CDS YP_003099477.1 256375817 8325867 1838611..1839615 1 NC_013093.1 KEGG: scl:sce4299 peptide ABC transporter, ATP- binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 1839615 8325867 Amir_1682 Actinosynnema mirum DSM 43827 oligopeptide/dipeptide ABC transporter ATPase subunit YP_003099477.1 1838611 D 446462 CDS YP_003099478.1 256375818 8325868 1839636..1841039 1 NC_013093.1 KEGG: rfr:Rfer_1102 beta-glucosidase; TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; beta-galactosidase 1841039 8325868 Amir_1683 Actinosynnema mirum DSM 43827 beta-galactosidase YP_003099478.1 1839636 D 446462 CDS YP_003099479.1 256375819 8325869 1841213..1842778 1 NC_013093.1 KEGG: hypothetical protein LOC758923; hypothetical protein 1842778 8325869 Amir_1684 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099479.1 1841213 D 446462 CDS YP_003099480.1 256375820 8325870 1842769..1843434 1 NC_013093.1 PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: cti:RALTA_A2171 serine/threonine protein phosphatase, P2C family; protein serine/threonine phosphatase 1843434 8325870 Amir_1685 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003099480.1 1842769 D 446462 CDS YP_003099481.1 256375821 8325871 1843431..1843991 1 NC_013093.1 hypothetical protein 1843991 8325871 Amir_1686 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099481.1 1843431 D 446462 CDS YP_003099482.1 256375822 8325872 1844064..1844288 1 NC_013093.1 hypothetical protein 1844288 8325872 Amir_1687 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099482.1 1844064 D 446462 CDS YP_003099483.1 256375823 8325873 1844502..1844981 1 NC_013093.1 PFAM: TspO/MBR family protein; KEGG: xca:xccb100_2086 peripheral-type benzodiazepine receptor; TspO and MBR like protein 1844981 8325873 Amir_1688 Actinosynnema mirum DSM 43827 TspO and MBR like protein YP_003099483.1 1844502 D 446462 CDS YP_003099484.1 256375824 8325874 1845119..1845670 1 NC_013093.1 PFAM: protein of unknown function DUF664; hypothetical protein 1845670 8325874 Amir_1689 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099484.1 1845119 D 446462 CDS YP_003099485.1 256375825 8325875 complement(1845791..1846897) 1 NC_013093.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1846897 ruvB 8325875 ruvB Actinosynnema mirum DSM 43827 Holliday junction DNA helicase RuvB YP_003099485.1 1845791 R 446462 CDS YP_003099486.1 256375826 8325876 complement(1846894..1847490) 1 NC_013093.1 KEGG: ade:Adeh_0952 Holliday junction DNA helicase RuvA; TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; RuvA domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; Holliday junction DNA helicase RuvA 1847490 8325876 Amir_1691 Actinosynnema mirum DSM 43827 Holliday junction DNA helicase RuvA YP_003099486.1 1846894 R 446462 CDS YP_003099487.1 256375827 8325877 complement(1847487..1848479) 1 NC_013093.1 KEGG: tgr:Tgr7_2236 crossover junction endodeoxyribonuclease; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; crossover junction endodeoxyribonuclease RuvC 1848479 8325877 Amir_1692 Actinosynnema mirum DSM 43827 crossover junction endodeoxyribonuclease RuvC YP_003099487.1 1847487 R 446462 CDS YP_003099488.1 256375828 8325878 1848685..1850268 1 NC_013093.1 KEGG: dvm:DvMF_0211 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 1850268 8325878 Amir_1693 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003099488.1 1848685 D 446462 CDS YP_003099489.1 256375829 8325879 1850628..1851029 1 NC_013093.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mag:amb2515 preprotein translocase subunit YajC; preprotein translocase subunit YajC 1851029 8325879 Amir_1694 Actinosynnema mirum DSM 43827 preprotein translocase subunit YajC YP_003099489.1 1850628 D 446462 CDS YP_003099490.1 256375830 8325880 1851179..1853077 1 NC_013093.1 TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: oca:OCAR_6254 protein-export membrane protein SecD; protein-export membrane protein SecD 1853077 8325880 Amir_1695 Actinosynnema mirum DSM 43827 protein-export membrane protein SecD YP_003099490.1 1851179 D 446462 CDS YP_003099491.1 256375831 8325881 1853079..1854269 1 NC_013093.1 TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: cbc:CbuK_1009 protein translocase subunit; protein-export membrane protein SecF 1854269 8325881 Amir_1696 Actinosynnema mirum DSM 43827 protein-export membrane protein SecF YP_003099491.1 1853079 D 446462 CDS YP_003099492.1 256375832 8325882 1854293..1854784 1 NC_013093.1 PFAM: phosphoribosyltransferase; KEGG: scl:sce2983 adenine phosphoribosyltransferase; adenine phosphoribosyltransferase 1854784 8325882 Amir_1697 Actinosynnema mirum DSM 43827 adenine phosphoribosyltransferase YP_003099492.1 1854293 D 446462 CDS YP_003099493.1 256375833 8325883 1854932..1857232 1 NC_013093.1 KEGG: bha:BH1242 GTP pyrophosphokinase (stringent response); TIGRFAM: RelA/SpoT family protein; PFAM: RelA/SpoT domain protein; TGS domain protein; amino acid-binding ACT domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; (p)ppGpp synthetase I SpoT/RelA 1857232 8325883 Amir_1698 Actinosynnema mirum DSM 43827 (p)ppGpp synthetase I SpoT/RelA YP_003099493.1 1854932 D 446462 CDS YP_003099494.1 256375834 8325884 complement(1857403..1858248) 1 NC_013093.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: hypothetical protein; K01802 peptidylprolyl isomerase; cyclophilin type peptidyl-prolyl cis-trans isomerase 1858248 8325884 Amir_1699 Actinosynnema mirum DSM 43827 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_003099494.1 1857403 R 446462 CDS YP_003099495.1 256375835 8325885 1858464..1859168 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: glo:Glov_3342 beta-lactamase domain protein; beta-lactamase domain-containing protein 1859168 8325885 Amir_1700 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003099495.1 1858464 D 446462 CDS YP_003099496.1 256375836 8325886 1859178..1860443 1 NC_013093.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1860443 hisS 8325886 hisS Actinosynnema mirum DSM 43827 histidyl-tRNA synthetase YP_003099496.1 1859178 D 446462 CDS YP_003099497.1 256375837 8325887 1860458..1861144 1 NC_013093.1 hypothetical protein 1861144 8325887 Amir_1702 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099497.1 1860458 D 446462 CDS YP_003099498.1 256375838 8325888 complement(1861201..1861602) 1 NC_013093.1 hypothetical protein 1861602 8325888 Amir_1703 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099498.1 1861201 R 446462 CDS YP_003099499.1 256375839 8325889 complement(1862025..1862888) 1 NC_013093.1 KEGG: mxa:MXAN_2295 hypothetical protein; spermidine synthase-like protein 1862888 8325889 Amir_1704 Actinosynnema mirum DSM 43827 spermidine synthase-like protein YP_003099499.1 1862025 R 446462 CDS YP_003099500.1 256375840 8325890 1862983..1863336 1 NC_013093.1 PFAM: protein of unknown function DUF1304; KEGG: atc:AGR_L_3168 hypothetical protein; hypothetical protein 1863336 8325890 Amir_1705 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099500.1 1862983 D 446462 CDS YP_003099501.1 256375841 8325891 complement(1863263..1864804) 1 NC_013093.1 PFAM: YibE/F family protein; KEGG: mgm:Mmc1_2300 YibE/F family protein; YibE/F family protein 1864804 8325891 Amir_1706 Actinosynnema mirum DSM 43827 YibE/F family protein YP_003099501.1 1863263 R 446462 CDS YP_003099502.1 256375842 8325892 1864829..1865713 1 NC_013093.1 hypothetical protein 1865713 8325892 Amir_1707 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099502.1 1864829 D 446462 CDS YP_003099503.1 256375843 8325893 1865827..1866204 1 NC_013093.1 KEGG: acp:A2cp1_3441 hypothetical protein; hypothetical protein 1866204 8325893 Amir_1708 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099503.1 1865827 D 446462 CDS YP_003099504.1 256375844 8325894 1866345..1866932 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mxa:MXAN_0079 transcriptional regulator, TetR family; TetR family transcriptional regulator 1866932 8325894 Amir_1709 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099504.1 1866345 D 446462 CDS YP_003099505.1 256375845 8325895 1867353..1868351 1 NC_013093.1 KEGG: dal:Dalk_2661 wyosine base formation; hypothetical protein 1868351 8325895 Amir_1710 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099505.1 1867353 D 446462 CDS YP_003099506.1 256375846 8325897 1869963..1871558 1 NC_013093.1 PFAM: carboxyl transferase; KEGG: ppu:PP_4065 propionyl-CoA carboxylase; propionyl-CoA carboxylase 1871558 8325897 Amir_1712 Actinosynnema mirum DSM 43827 propionyl-CoA carboxylase YP_003099506.1 1869963 D 446462 CDS YP_003099507.1 256375847 8325898 1871566..1873596 1 NC_013093.1 PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; protein of unknown function DUF201; biotin/lipoyl attachment domain- containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: bra:BRADO6875 biotin carboxylase; carbamoyl-phosphate synthase L chain ATP- binding 1873596 8325898 Amir_1713 Actinosynnema mirum DSM 43827 carbamoyl-phosphate synthase L chain ATP- binding YP_003099507.1 1871566 D 446462 CDS YP_003099508.1 256375848 8325899 1873593..1874753 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bxe:Bxe_C0513 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 1874753 8325899 Amir_1714 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003099508.1 1873593 D 446462 CDS YP_003099509.1 256375849 8325900 complement(1874794..1875762) 1 NC_013093.1 KEGG: ccs:CCNA_00655 hypothetical protein; hypothetical protein 1875762 8325900 Amir_1715 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099509.1 1874794 R 446462 CDS YP_003099510.1 256375850 8325901 complement(1876296..1876469) 1 NC_013093.1 hypothetical protein 1876469 8325901 Amir_1716 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099510.1 1876296 R 446462 CDS YP_003099511.1 256375851 8325902 1876598..1877743 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 1877743 8325902 Amir_1717 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003099511.1 1876598 D 446462 CDS YP_003099512.1 256375852 8325903 1878010..1879203 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: swd:Swoo_2373 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 1879203 8325903 Amir_1718 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003099512.1 1878010 D 446462 CDS YP_003099513.1 256375853 8325904 1879378..1881156 1 NC_013093.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1881156 aspS 8325904 aspS Actinosynnema mirum DSM 43827 aspartyl-tRNA synthetase YP_003099513.1 1879378 D 446462 CDS YP_003099514.1 256375854 8325905 1881662..1882846 1 NC_013093.1 KEGG: lpp:plpp0130 hypothetical protein; hypothetical protein 1882846 8325905 Amir_1720 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099514.1 1881662 D 446462 CDS YP_003099515.1 256375855 8325906 complement(1883100..1884374) 1 NC_013093.1 PFAM: glycosyl transferase family 2; GtrA family protein; KEGG: ppd:Ppro_2693 glycosyl transferase family protein; family 2 glycosyl transferase 1884374 8325906 Amir_1721 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003099515.1 1883100 R 446462 CDS YP_003099516.1 256375856 8325907 complement(1884413..1886338) 1 NC_013093.1 PFAM: glycosyl transferase family 39; KEGG: bsu:BSU12880 hypothetical protein; glycosyl transferase family protein 1886338 8325907 Amir_1722 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003099516.1 1884413 R 446462 CDS YP_003099517.1 256375857 8325908 complement(1886424..1887908) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sus:Acid_6896 heavy metal sensor signal transduction histidine kinase; histidine kinase 1887908 8325908 Amir_1723 Actinosynnema mirum DSM 43827 histidine kinase YP_003099517.1 1886424 R 446462 CDS YP_003099518.1 256375858 8325909 complement(1887886..1888617) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bat:BAS2056 DNA-binding response regulator; winged helix family two component transcriptional regulator 1888617 8325909 Amir_1724 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003099518.1 1887886 R 446462 CDS YP_003099519.1 256375859 8325910 1888831..1889538 1 NC_013093.1 KEGG: bce:BC0440 surface protein; hypothetical protein 1889538 8325910 Amir_1725 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099519.1 1888831 D 446462 CDS YP_003099520.1 256375860 8325911 1889771..1890394 1 NC_013093.1 PFAM: copper resistance protein CopC; KEGG: rpc:RPC_2426 copper resistance D; copper resistance protein CopC 1890394 8325911 Amir_1726 Actinosynnema mirum DSM 43827 copper resistance protein CopC YP_003099520.1 1889771 D 446462 CDS YP_003099521.1 256375861 8325912 1890678..1891280 1 NC_013093.1 PFAM: uracil-DNA glycosylase; KEGG: scl:sce5098 G/U mismatch-specific DNA glycosylase; uracil-DNA glycosylase 1891280 8325912 Amir_1727 Actinosynnema mirum DSM 43827 uracil-DNA glycosylase YP_003099521.1 1890678 D 446462 CDS YP_003099522.1 256375862 8325913 complement(1891218..1891976) 1 NC_013093.1 PFAM: protein of unknown function DUF742; KEGG: hypothetical protein; hypothetical protein 1891976 8325913 Amir_1728 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099522.1 1891218 R 446462 CDS YP_003099523.1 256375863 8325914 1892166..1892441 1 NC_013093.1 PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: dps:DP2177 hypothetical protein; RNA-binding S4 domain-containing protein 1892441 8325914 Amir_1729 Actinosynnema mirum DSM 43827 RNA-binding S4 domain-containing protein YP_003099523.1 1892166 D 446462 CDS YP_003099524.1 256375864 8325915 1893873..1895276 1 NC_013093.1 KEGG: ank:AnaeK_2858 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 1895276 8325915 Amir_1730 Actinosynnema mirum DSM 43827 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_003099524.1 1893873 D 446462 CDS YP_003099525.1 256375865 8325916 1895276..1896370 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: ret:RHE_CH01364 oxidoreductase protein; oxidoreductase domain-containing protein 1896370 8325916 Amir_1731 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003099525.1 1895276 D 446462 CDS YP_003099526.1 256375866 8325917 1896367..1896969 1 NC_013093.1 KEGG: cvi:CV_4013 dTDP-6-deoxy-D-glucose-3,5 epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 1896969 8325917 Amir_1732 Actinosynnema mirum DSM 43827 dTDP-4-dehydrorhamnose 3,5-epimerase YP_003099526.1 1896367 D 446462 CDS YP_003099527.1 256375867 8325918 1896966..1897940 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4- dehydrorhamnose reductase; short-chain dehydrogenase/reductase SDR; KEGG: rlt:Rleg2_6416 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 1897940 8325918 Amir_1733 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003099527.1 1896966 D 446462 CDS YP_003099528.1 256375868 8325919 1897937..1899052 1 NC_013093.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mrd:Mrad2831_4616 DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 1899052 8325919 Amir_1734 Actinosynnema mirum DSM 43827 DegT/DnrJ/EryC1/StrS aminotransferase YP_003099528.1 1897937 D 446462 CDS YP_003099529.1 256375869 8325920 1899295..1904178 1 NC_013093.1 KEGG: rle:pRL90161 hypothetical protein; hypothetical protein 1904178 8325920 Amir_1735 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099529.1 1899295 D 446462 CDS YP_003099530.1 256375870 8325921 1904193..1904849 1 NC_013093.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: acetyltransferase; transferase hexapeptide repeat containing protein 1904849 8325921 Amir_1736 Actinosynnema mirum DSM 43827 transferase hexapeptide repeat containing protein YP_003099530.1 1904193 D 446462 CDS YP_003099531.1 256375871 8325922 1904846..1905943 1 NC_013093.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: aba:Acid345_1081 DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 1905943 8325922 Amir_1737 Actinosynnema mirum DSM 43827 DegT/DnrJ/EryC1/StrS aminotransferase YP_003099531.1 1904846 D 446462 CDS YP_003099532.1 256375872 8325923 1905940..1906545 1 NC_013093.1 KEGG: xcv:XCV3714 bifunctional isomerase / acetyl transferase; N-acetylglucosamine-1- phosphateuridyltransferase-like protein 1906545 8325923 Amir_1738 Actinosynnema mirum DSM 43827 N-acetylglucosamine-1- phosphateuridyltransferase-like protein YP_003099532.1 1905940 D 446462 CDS YP_003099533.1 256375873 8325924 complement(1906676..1908073) 1 NC_013093.1 PFAM: O-antigen polymerase; KEGG: mxa:MXAN_3026 O-antigen polymerase family protein; O-antigen polymerase 1908073 8325924 Amir_1739 Actinosynnema mirum DSM 43827 O-antigen polymerase YP_003099533.1 1906676 R 446462 CDS YP_003099534.1 256375874 8325925 complement(1908073..1909209) 1 NC_013093.1 KEGG: dvu:DVU0508 translation initiation factor IF- 2; hypothetical protein 1909209 8325925 Amir_1740 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099534.1 1908073 R 446462 CDS YP_003099535.1 256375875 8325926 1909305..1910264 1 NC_013093.1 KEGG: sus:Acid_4999 peptidase S9B dipeptidylpeptidase IV subunit; hypothetical protein 1910264 8325926 Amir_1741 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099535.1 1909305 D 446462 CDS YP_003099536.1 256375876 8325927 complement(1910281..1910412) 1 NC_013093.1 hypothetical protein 1910412 8325927 Amir_1742 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099536.1 1910281 R 446462 CDS YP_003099537.1 256375877 8325928 complement(1910513..1911733) 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: rme:Rmet_4154 transposase, IS4 family; transposase IS4 family protein 1911733 8325928 Amir_1743 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003099537.1 1910513 R 446462 CDS YP_003099538.1 256375878 8325929 1911891..1912421 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nar:Saro_3542 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1912421 8325929 Amir_1744 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003099538.1 1911891 D 446462 CDS YP_003099539.1 256375879 8325930 complement(1912915..1914135) 1 NC_013093.1 KEGG: smd:Smed_4803 glycosyl transferase group 1; group 1 glycosyl transferase 1914135 8325930 Amir_1745 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003099539.1 1912915 R 446462 CDS YP_003099540.1 256375880 8325931 complement(1914132..1915661) 1 NC_013093.1 PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; multi antimicrobial extrusion protein MatE; KEGG: pol:Bpro_1890 polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 1915661 8325931 Amir_1746 Actinosynnema mirum DSM 43827 polysaccharide biosynthesis protein YP_003099540.1 1914132 R 446462 CDS YP_003099541.1 256375881 8325932 complement(1915658..1916716) 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: smd:Smed_4802 glycosyl transferase family 2; family 2 glycosyl transferase 1916716 8325932 Amir_1747 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003099541.1 1915658 R 446462 CDS YP_003099542.1 256375882 8325933 1916800..1917648 1 NC_013093.1 KEGG: pat:Patl_2044 hypothetical protein; hypothetical protein 1917648 8325933 Amir_1748 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099542.1 1916800 D 446462 CDS YP_003099543.1 256375883 8325934 1917690..1918949 1 NC_013093.1 KEGG: smd:Smed_4798 hypothetical protein; hypothetical protein 1918949 8325934 Amir_1749 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099543.1 1917690 D 446462 CDS YP_003099544.1 256375884 8325935 1919236..1920591 1 NC_013093.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein; KEGG: bca:BCE_2353 triple helix repeat-containing COllagen; 40-residue YVTN family beta-propeller repeat-containing protein 1920591 8325935 Amir_1750 Actinosynnema mirum DSM 43827 40-residue YVTN family beta-propeller repeat-containing protein YP_003099544.1 1919236 D 446462 CDS YP_003099545.1 256375885 8325936 complement(1921062..1922324) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: rce:RC1_3626 major facilitator superfamily transport protein; major facilitator superfamily protein 1922324 8325936 Amir_1751 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099545.1 1921062 R 446462 CDS YP_003099546.1 256375886 8325937 1922419..1923273 1 NC_013093.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: lch:Lcho_2341 WecB/TagA/CpsF family glycosyl transferase; WecB/TagA/CpsF family glycosyl transferase 1923273 8325937 Amir_1752 Actinosynnema mirum DSM 43827 WecB/TagA/CpsF family glycosyl transferase YP_003099546.1 1922419 D 446462 CDS YP_003099547.1 256375887 8325938 1923276..1925393 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: ank:AnaeK_2727 hypothetical protein; family 2 glycosyl transferase 1925393 8325938 Amir_1753 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003099547.1 1923276 D 446462 CDS YP_003099548.1 256375888 8325939 1925587..1927194 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; protein of unknown function RIO1; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: tbd:Tbd_1700 serine/threonine protein kinase; serine/threonine protein kinase 1927194 8325939 Amir_1754 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003099548.1 1925587 D 446462 CDS YP_003099549.1 256375889 8325940 1927409..1929025 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1929025 8325940 Amir_1755 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003099549.1 1927409 D 446462 CDS YP_003099550.1 256375890 8325941 complement(1929433..1930218) 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bbt:BBta_2630 enoyl-CoA hydratase; Enoyl-CoA hydratase/isomerase 1930218 8325941 Amir_1756 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003099550.1 1929433 R 446462 CDS YP_003099551.1 256375891 8325942 1930294..1930761 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: met:M446_1745 MarR family transcriptional regulator; GCN5-like N-acetyltransferase 1930761 8325942 Amir_1757 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003099551.1 1930294 D 446462 CDS YP_003099552.1 256375892 8325943 1930861..1931406 1 NC_013093.1 PFAM: YCII-related; regulatory protein LuxR; Sigma- 70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: reu:Reut_B5221 YCII-related; LuxR family transcriptional regulator 1931406 8325943 Amir_1758 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099552.1 1930861 D 446462 CDS YP_003099553.1 256375893 8325944 1931594..1932055 1 NC_013093.1 PFAM: thioesterase superfamily protein; KEGG: acp:A2cp1_3885 thioesterase superfamily protein; thioesterase superfamily protein 1932055 8325944 Amir_1759 Actinosynnema mirum DSM 43827 thioesterase superfamily protein YP_003099553.1 1931594 D 446462 CDS YP_003099554.1 256375894 8325945 1932137..1932700 1 NC_013093.1 hypothetical protein 1932700 8325945 Amir_1760 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099554.1 1932137 D 446462 CDS YP_003099555.1 256375895 8325946 complement(1932807..1934399) 1 NC_013093.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: scl:sce3770 phytoene dehydrogenase- related protein; amine oxidase 1934399 8325946 Amir_1761 Actinosynnema mirum DSM 43827 amine oxidase YP_003099555.1 1932807 R 446462 CDS YP_003099556.1 256375896 8325947 1934811..1937168 1 NC_013093.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; RNA binding S1 domain protein; KEGG: bja:bll7280 hypothetical protein; RNA binding S1 domain-containing protein 1937168 8325947 Amir_1762 Actinosynnema mirum DSM 43827 RNA binding S1 domain-containing protein YP_003099556.1 1934811 D 446462 CDS YP_003099557.1 256375897 8325948 complement(1937262..1938287) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: rle:RL2983 aldo/keto reductase; aldo/keto reductase 1938287 8325948 Amir_1763 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003099557.1 1937262 R 446462 CDS YP_003099558.1 256375898 8325949 1938464..1939318 1 NC_013093.1 KEGG: rfr:Rfer_1474 hypothetical protein; hypothetical protein 1939318 8325949 Amir_1764 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099558.1 1938464 D 446462 CDS YP_003099559.1 256375899 8325950 1939422..1940177 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: nar:Saro_3457 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 1940177 8325950 Amir_1765 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003099559.1 1939422 D 446462 CDS YP_003099560.1 256375900 8325951 complement(1940174..1940764) 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vei:Veis_4651 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 1940764 8325951 Amir_1766 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003099560.1 1940174 R 446462 CDS YP_003099561.1 256375901 8325952 complement(1940928..1941077) 1 NC_013093.1 hypothetical protein 1941077 8325952 Amir_1767 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099561.1 1940928 R 446462 CDS YP_003099562.1 256375902 8325953 complement(1941360..1941641) 1 NC_013093.1 KEGG: bmn:BMA10247_A2255 hypothetical protein; hypothetical protein 1941641 8325953 Amir_1768 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099562.1 1941360 R 446462 CDS YP_003099563.1 256375903 8325954 complement(1941641..1943437) 1 NC_013093.1 KEGG: SNF2 superfamily protein; SNF2 superfamily protein 1943437 8325954 Amir_1769 Actinosynnema mirum DSM 43827 SNF2 superfamily protein YP_003099563.1 1941641 R 446462 CDS YP_003099564.1 256375904 8325955 1943564..1944487 1 NC_013093.1 PFAM: ribonuclease BN; KEGG: ppu:PP_4560 ribonuclease BN; ribonuclease BN 1944487 8325955 Amir_1770 Actinosynnema mirum DSM 43827 ribonuclease BN YP_003099564.1 1943564 D 446462 CDS YP_003099565.1 256375905 8325956 1944575..1945168 1 NC_013093.1 KEGG: noc:Noc_1876 hypothetical protein; hypothetical protein 1945168 8325956 Amir_1771 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099565.1 1944575 D 446462 CDS YP_003099566.1 256375906 8325957 complement(1945174..1946916) 1 NC_013093.1 PFAM: YheO domain protein; aminotransferase class V; KEGG: mxa:MXAN_1570 aminotransferase, class V; YheO domain-containing protein 1946916 8325957 Amir_1772 Actinosynnema mirum DSM 43827 YheO domain-containing protein YP_003099566.1 1945174 R 446462 CDS YP_003099567.1 256375907 8325958 complement(1946919..1947677) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bac:BamMC406_6166 ABC transporter; ABC transporter 1947677 8325958 Amir_1773 Actinosynnema mirum DSM 43827 ABC transporter YP_003099567.1 1946919 R 446462 CDS YP_003099568.1 256375908 8325959 complement(1947674..1948525) 1 NC_013093.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_2097 ABC transporter permease; polar amino acid ABC transporter, inner membrane subunit 1948525 8325959 Amir_1774 Actinosynnema mirum DSM 43827 polar amino acid ABC transporter, inner membrane subunit YP_003099568.1 1947674 R 446462 CDS YP_003099569.1 256375909 8325960 complement(1948515..1949453) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: rle:RL0985 solute-binding component of ABC transporter; family 3 extracellular solute-binding protein 1949453 8325960 Amir_1775 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003099569.1 1948515 R 446462 CDS YP_003099570.1 256375910 8325961 1949620..1950015 1 NC_013093.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: ank:AnaeK_2254 thioredoxin; thioredoxin 1950015 8325961 Amir_1776 Actinosynnema mirum DSM 43827 thioredoxin YP_003099570.1 1949620 D 446462 CDS YP_003099571.1 256375911 8325962 1950286..1950678 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 1950678 8325962 Amir_1777 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003099571.1 1950286 D 446462 CDS YP_003099572.1 256375912 8325963 1950675..1951853 1 NC_013093.1 KEGG: bch:Bcen2424_1675 precorrin-6y C5,15- methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-6y C5,15-methyltransferase , CbiE subunit 1951853 8325963 Amir_1778 Actinosynnema mirum DSM 43827 precorrin-6y C5,15-methyltransferase , CbiE subunit YP_003099572.1 1950675 D 446462 CDS YP_003099573.1 256375913 8325964 1951850..1952602 1 NC_013093.1 KEGG: bov:BOV_1262 precorrin-4 C11- methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-4 C11-methyltransferase 1952602 8325964 Amir_1779 Actinosynnema mirum DSM 43827 precorrin-4 C11-methyltransferase YP_003099573.1 1951850 D 446462 CDS YP_003099574.1 256375914 8325965 1952602..1953327 1 NC_013093.1 KEGG: rru:Rru_A2988 precorrin-6A reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; precorrin-6x reductase 1953327 8325965 Amir_1780 Actinosynnema mirum DSM 43827 precorrin-6x reductase YP_003099574.1 1952602 D 446462 CDS YP_003099575.1 256375915 8325966 complement(1953332..1954882) 1 NC_013093.1 TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: met:M446_2442 precorrin-3B C17- methyltransferase; precorrin-3B C17-methyltransferase 1954882 8325966 Amir_1781 Actinosynnema mirum DSM 43827 precorrin-3B C17-methyltransferase YP_003099575.1 1953332 R 446462 CDS YP_003099576.1 256375916 8325967 complement(1954879..1955505) 1 NC_013093.1 PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: pmy:Pmen_4572 precorrin-8X methylmutase; Precorrin-8X methylmutase 1955505 8325967 Amir_1782 Actinosynnema mirum DSM 43827 Precorrin-8X methylmutase YP_003099576.1 1954879 R 446462 CDS YP_003099577.1 256375917 8325968 complement(1955502..1956539) 1 NC_013093.1 KEGG: bja:blr3264 hypothetical protein; hypothetical protein 1956539 8325968 Amir_1783 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099577.1 1955502 R 446462 CDS YP_003099578.1 256375918 8325969 1956717..1960298 1 NC_013093.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 1960298 cobN 8325969 cobN Actinosynnema mirum DSM 43827 cobaltochelatase subunit CobN YP_003099578.1 1956717 D 446462 CDS YP_003099579.1 256375919 8325970 1961227..1962501 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1924 sugar transport system (sugar- binding protein); family 1 extracellular solute-binding protein 1962501 8325970 Amir_1785 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003099579.1 1961227 D 446462 CDS YP_003099580.1 256375920 8325971 1962498..1963505 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1925 sugar transport system (permease); ABC transporter inner membrane protein 1963505 8325971 Amir_1786 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099580.1 1962498 D 446462 CDS YP_003099581.1 256375921 8325972 1963509..1964327 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1926 sugar transport system (permease); ABC transporter inner membrane protein 1964327 8325972 Amir_1787 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099581.1 1963509 D 446462 CDS YP_003099582.1 256375922 8325973 1964330..1965748 1 NC_013093.1 KEGG: hch:HCH_06907 beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase; TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; beta-galactosidase 1965748 8325973 Amir_1788 Actinosynnema mirum DSM 43827 beta-galactosidase YP_003099582.1 1964330 D 446462 CDS YP_003099583.1 256375923 8325974 1965745..1966776 1 NC_013093.1 KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 1966776 8325974 Amir_1789 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099583.1 1965745 D 446462 CDS YP_003099584.1 256375924 8325975 complement(1966842..1967081) 1 NC_013093.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: psp:PSPPH_B0015 prevent-host-death family protein; prevent-host-death family protein 1967081 8325975 Amir_1790 Actinosynnema mirum DSM 43827 prevent-host-death family protein YP_003099584.1 1966842 R 446462 CDS YP_003099585.1 256375925 8325976 1967594..1970335 1 NC_013093.1 PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: cja:CJA_2477 endo-1,4-beta- glucanase/xyloglucanase, , gly74A; cellulose-binding family protein 1970335 8325976 Amir_1791 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003099585.1 1967594 D 446462 CDS YP_003099586.1 256375926 8325977 complement(1970531..1970758) 1 NC_013093.1 hypothetical protein 1970758 8325977 Amir_1792 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099586.1 1970531 R 446462 CDS YP_003099587.1 256375927 8325978 complement(1971079..1973784) 1 NC_013093.1 PFAM: hypothetical protein; SMART: helix-turn-helix domain protein; hypothetical protein; KEGG: scl:sce5991 protein kinase; XRE family transcriptional regulator 1973784 8325978 Amir_1793 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003099587.1 1971079 R 446462 CDS YP_003099588.1 256375928 8325979 complement(1974385..1975533) 1 NC_013093.1 PFAM: ROK family protein; KEGG: acr:Acry_0116 ROK family protein; ROK family protein 1975533 8325979 Amir_1794 Actinosynnema mirum DSM 43827 ROK family protein YP_003099588.1 1974385 R 446462 CDS YP_003099589.1 256375929 8325980 1976134..1977273 1 NC_013093.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1977273 8325980 Amir_1795 Actinosynnema mirum DSM 43827 xylose isomerase YP_003099589.1 1976134 D 446462 CDS YP_003099590.1 256375930 8325981 1977273..1978655 1 NC_013093.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: pen:PSEEN1988 xylulokinase; xylulokinase 1978655 8325981 Amir_1796 Actinosynnema mirum DSM 43827 xylulokinase YP_003099590.1 1977273 D 446462 CDS YP_003099591.1 256375931 8325982 complement(1979137..1979373) 1 NC_013093.1 hypothetical protein 1979373 8325982 Amir_1797 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099591.1 1979137 R 446462 CDS YP_003099592.1 256375932 8325983 1979436..1980020 1 NC_013093.1 KEGG: afw:Anae109_0147 hypothetical protein; hypothetical protein 1980020 8325983 Amir_1798 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099592.1 1979436 D 446462 CDS YP_003099593.1 256375933 8325984 1980017..1980271 1 NC_013093.1 hypothetical protein 1980271 8325984 Amir_1799 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099593.1 1980017 D 446462 CDS YP_003099594.1 256375934 8325985 1980268..1981011 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: mes:Meso_2768 metallophosphoesterase; metallophosphoesterase 1981011 8325985 Amir_1800 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003099594.1 1980268 D 446462 CDS YP_003099595.1 256375935 8325986 complement(1981090..1981707) 1 NC_013093.1 PFAM: cyclase/dehydrase; KEGG: mfa:Mfla_0007 cyclase/dehydrase; cyclase/dehydrase 1981707 8325986 Amir_1801 Actinosynnema mirum DSM 43827 cyclase/dehydrase YP_003099595.1 1981090 R 446462 CDS YP_003099596.1 256375936 8325987 1981969..1982829 1 NC_013093.1 PFAM: transcription activator effector binding; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bsu:BSU05170 hypothetical protein; AraC family transcriptional regulator 1982829 8325987 Amir_1802 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003099596.1 1981969 D 446462 CDS YP_003099597.1 256375937 8325988 complement(1982881..1984059) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: mrd:Mrad2831_6253 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 1984059 8325988 Amir_1803 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003099597.1 1982881 R 446462 CDS YP_003099598.1 256375938 8325989 complement(1984174..1984575) 1 NC_013093.1 KEGG: azo:azo1781 hypothetical protein; hypothetical protein 1984575 8325989 Amir_1804 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099598.1 1984174 R 446462 CDS YP_003099599.1 256375939 8325990 complement(1984628..1985140) 1 NC_013093.1 PFAM: transcriptional regulator domain protein; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 1985140 8325990 Amir_1805 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003099599.1 1984628 R 446462 CDS YP_003099600.1 256375940 8325991 1985515..1986342 1 NC_013093.1 hypothetical protein 1986342 8325991 Amir_1806 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099600.1 1985515 D 446462 CDS YP_003099601.1 256375941 8325992 complement(1986522..1987730) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_1009 sugar transport sugar binding protein; family 1 extracellular solute-binding protein 1987730 8325992 Amir_1807 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003099601.1 1986522 R 446462 CDS YP_003099602.1 256375942 8325993 1988153..1990270 1 NC_013093.1 KEGG: sus:Acid_1791 amino acid transporter; amino acid transporter 1990270 8325993 Amir_1808 Actinosynnema mirum DSM 43827 amino acid transporter YP_003099602.1 1988153 D 446462 CDS YP_003099603.1 256375943 8325994 complement(1990627..1992981) 1 NC_013093.1 PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; KEGG: mex:Mext_0562 kojibiose phosphorylase; Kojibiose phosphorylase 1992981 8325994 Amir_1809 Actinosynnema mirum DSM 43827 Kojibiose phosphorylase YP_003099603.1 1990627 R 446462 CDS YP_003099604.1 256375944 8325995 complement(1992978..1993694) 1 NC_013093.1 TIGRFAM: beta-phosphoglucomutase family hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ajs:Ajs_2161 beta-phosphoglucomutase family hydrolase; beta-phosphoglucomutase family hydrolase 1993694 8325995 Amir_1810 Actinosynnema mirum DSM 43827 beta-phosphoglucomutase family hydrolase YP_003099604.1 1992978 R 446462 CDS YP_003099605.1 256375945 8325996 1993794..1995122 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rsh:Rsph17029_3442 cyclic nucleotide- regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1995122 8325996 Amir_1811 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003099605.1 1993794 D 446462 CDS YP_003099606.1 256375946 8325997 complement(1995162..1995482) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: mxa:MXAN_5617 transcriptional regulator, ArsR family; ArsR family transcriptional regulator 1995482 8325997 Amir_1812 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003099606.1 1995162 R 446462 CDS YP_003099607.1 256375947 8325998 1995611..1996258 1 NC_013093.1 hypothetical protein 1996258 8325998 Amir_1813 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099607.1 1995611 D 446462 CDS YP_003099608.1 256375948 8325999 1996298..1996621 1 NC_013093.1 KEGG: PODXL2; podocalyxin-like 2; PODXL2; podocalyxin-like 2 1996621 8325999 Amir_1814 Actinosynnema mirum DSM 43827 PODXL2; podocalyxin-like 2 YP_003099608.1 1996298 D 446462 CDS YP_003099609.1 256375949 8326000 1996849..1997349 1 NC_013093.1 KEGG: rpi:Rpic_3996 alanine-rich signal peptide protein; hypothetical protein 1997349 8326000 Amir_1815 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099609.1 1996849 D 446462 CDS YP_003099610.1 256375950 8326001 complement(1997398..1997685) 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 1997685 8326001 Amir_1816 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003099610.1 1997398 R 446462 CDS YP_003099611.1 256375951 8326002 complement(1997743..1998606) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: scl:sce0579 MerR family transcriptional regulator; MerR family transcriptional regulator 1998606 8326002 Amir_1817 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003099611.1 1997743 R 446462 CDS YP_003099612.1 256375952 8326003 1999168..1999902 1 NC_013093.1 signal transduction histidine kinase 1999902 8326003 Amir_1818 Actinosynnema mirum DSM 43827 signal transduction histidine kinase YP_003099612.1 1999168 D 446462 CDS YP_003099613.1 256375953 8326004 complement(1999939..2000274) 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: pde:Pden_0820 anti-sigma-factor antagonist; anti-sigma-factor antagonist 2000274 8326004 Amir_1819 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003099613.1 1999939 R 446462 CDS YP_003099614.1 256375954 8326005 complement(2000400..2001392) 1 NC_013093.1 PFAM: NLP/P60 protein; KEGG: dvu:DVU1392 NLP/P60 family protein; NLP/P60 protein 2001392 8326005 Amir_1820 Actinosynnema mirum DSM 43827 NLP/P60 protein YP_003099614.1 2000400 R 446462 CDS YP_003099615.1 256375955 8326006 2001648..2002934 1 NC_013093.1 KEGG: sit:TM1040_2323 hypothetical protein; hypothetical protein 2002934 8326006 Amir_1821 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099615.1 2001648 D 446462 CDS YP_003099616.1 256375956 8326007 2003094..2004383 1 NC_013093.1 PFAM: chitin-binding domain 3 protein; Fibronectin type III domain protein; cellulose-binding family II; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: pag:PLES_44661 chitin-binding protein CbpD precursor; chitin-binding domain 3 protein 2004383 8326007 Amir_1822 Actinosynnema mirum DSM 43827 chitin-binding domain 3 protein YP_003099616.1 2003094 D 446462 CDS YP_003099617.1 256375957 8326008 2004380..2004925 1 NC_013093.1 hypothetical protein 2004925 8326008 Amir_1823 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099617.1 2004380 D 446462 CDS YP_003099618.1 256375958 8326009 complement(2004936..2005979) 1 NC_013093.1 KEGG: yen:YE0107 DNA-binding transcriptional regulator CytR; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2005979 8326009 Amir_1824 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099618.1 2004936 R 446462 CDS YP_003099619.1 256375959 8326010 2006247..2007287 1 NC_013093.1 KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2007287 8326010 Amir_1825 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099619.1 2006247 D 446462 CDS YP_003099620.1 256375960 8326011 2007329..2009644 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: esa:ESA_02100 hypothetical protein; glycoside hydrolase family protein 2009644 8326011 Amir_1826 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003099620.1 2007329 D 446462 CDS YP_003099621.1 256375961 8326012 2009767..2010693 1 NC_013093.1 hypothetical protein 2010693 8326012 Amir_1827 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099621.1 2009767 D 446462 CDS YP_003099622.1 256375962 8326013 complement(2011077..2012039) 1 NC_013093.1 PFAM: acetyl xylan esterase; peptidase S15; KEGG: mlo:mlr6993 acetyl xylan esterase; acetyl xylan esterase 2012039 8326013 Amir_1828 Actinosynnema mirum DSM 43827 acetyl xylan esterase YP_003099622.1 2011077 R 446462 CDS YP_003099623.1 256375963 8326014 2012723..2012995 1 NC_013093.1 hypothetical protein 2012995 8326014 Amir_1829 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099623.1 2012723 D 446462 CDS YP_003099624.1 256375964 8326015 2013242..2014873 1 NC_013093.1 PFAM: glycoside hydrolase family 5; Fibronectin type III domain protein; cellulose-binding family II; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: sde:Sde_0064 secreted beta- mannosidase; glycoside hydrolase family protein 2014873 8326015 Amir_1830 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003099624.1 2013242 D 446462 CDS YP_003099625.1 256375965 8326016 2014885..2016009 1 NC_013093.1 PFAM: cellulose-binding family II; lipolytic protein G-D-S-L family; SMART: cellulose-binding family II; KEGG: hypothetical protein; cellulose-binding family protein 2016009 8326016 Amir_1831 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003099625.1 2014885 D 446462 CDS YP_003099626.1 256375966 8326017 2016181..2016582 1 NC_013093.1 PFAM: YCII-related; KEGG: scl:sce5148 hypothetical protein; YCII-like protein 2016582 8326017 Amir_1832 Actinosynnema mirum DSM 43827 YCII-like protein YP_003099626.1 2016181 D 446462 CDS YP_003099627.1 256375967 8326018 2016750..2017862 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; KEGG: scl:sce5149 ECF subfamily RNA polymerase sigma-70 factor; RNA polymerase, sigma 70 family subunit 2017862 8326018 Amir_1833 Actinosynnema mirum DSM 43827 RNA polymerase, sigma 70 family subunit YP_003099627.1 2016750 D 446462 CDS YP_003099628.1 256375968 8326019 complement(2018046..2018225) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 2018225 8326019 Amir_1834 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099628.1 2018046 R 446462 CDS YP_003099629.1 256375969 8326020 complement(2018250..2019104) 1 NC_013093.1 SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 2019104 8326020 Amir_1835 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003099629.1 2018250 R 446462 CDS YP_003099630.1 256375970 8326021 2019292..2019525 1 NC_013093.1 hypothetical protein 2019525 8326021 Amir_1836 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099630.1 2019292 D 446462 CDS YP_003099631.1 256375971 8326022 2019522..2020394 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: hypothetical protein; helix-turn-helix domain-containing protein 2020394 8326022 Amir_1837 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003099631.1 2019522 D 446462 CDS YP_003099632.1 256375972 8326023 complement(2020504..2021010) 1 NC_013093.1 hypothetical protein 2021010 8326023 Amir_1838 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099632.1 2020504 R 446462 CDS YP_003099633.1 256375973 8326024 2021442..2023028 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: Foxred2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2023028 8326024 Amir_1839 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003099633.1 2021442 D 446462 CDS YP_003099634.1 256375974 8326025 2023192..2025039 1 NC_013093.1 KEGG: pca:Pcar_0512 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; Alkaline phosphatase 2025039 8326025 Amir_1840 Actinosynnema mirum DSM 43827 Alkaline phosphatase YP_003099634.1 2023192 D 446462 CDS YP_003099635.1 256375975 8326026 2025240..2026118 1 NC_013093.1 KEGG: rsh:Rsph17029_3026 hypothetical protein; hypothetical protein 2026118 8326026 Amir_1841 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099635.1 2025240 D 446462 CDS YP_003099636.1 256375976 8326027 complement(2026214..2027185) 1 NC_013093.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bvi:Bcep1808_3829 LacI family transcription regulator; LacI family transcriptional regulator 2027185 8326027 Amir_1842 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099636.1 2026214 R 446462 CDS YP_003099637.1 256375977 8326028 2027491..2029683 1 NC_013093.1 PFAM: pectate lyase/Amb allergen; pectinesterase; SMART: pectate lyase/Amb allergen; KEGG: bsu:BSU07560 pectate lyase; pectate lyase/Amb allergen 2029683 8326028 Amir_1843 Actinosynnema mirum DSM 43827 pectate lyase/Amb allergen YP_003099637.1 2027491 D 446462 CDS YP_003099638.1 256375978 8326029 2029680..2030555 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smd:Smed_0187 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2030555 8326029 Amir_1844 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099638.1 2029680 D 446462 CDS YP_003099639.1 256375979 8326030 2030552..2031439 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smd:Smed_2422 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2031439 8326030 Amir_1845 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099639.1 2030552 D 446462 CDS YP_003099640.1 256375980 8326031 2031447..2032724 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: rle:pRL110364 substrate-binding component of ABC transporter; family 1 extracellular solute-binding protein 2032724 8326031 Amir_1846 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003099640.1 2031447 D 446462 CDS YP_003099641.1 256375981 8326032 2032721..2033869 1 NC_013093.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: ent:Ent638_2707 mandelate racemase/muconate lactonizing protein; mandelate racemase/muconate lactonizing protein 2033869 8326032 Amir_1847 Actinosynnema mirum DSM 43827 mandelate racemase/muconate lactonizing protein YP_003099641.1 2032721 D 446462 CDS YP_003099642.1 256375982 8326033 2033980..2034933 1 NC_013093.1 PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; Parallel beta- helix repeat; KEGG: pectate lyase; pectate lyase/Amb allergen 2034933 8326033 Amir_1848 Actinosynnema mirum DSM 43827 pectate lyase/Amb allergen YP_003099642.1 2033980 D 446462 CDS YP_003099643.1 256375983 8326034 2035048..2036091 1 NC_013093.1 PFAM: ketopantoate reductase ApbA/PanE domain protein; KEGG: gdi:GDI0989 2-dehydropantoate 2- reductase; ketopantoate reductase ApbA/PanE domain-containing protein 2036091 8326034 Amir_1849 Actinosynnema mirum DSM 43827 ketopantoate reductase ApbA/PanE domain-containing protein YP_003099643.1 2035048 D 446462 CDS YP_003099644.1 256375984 8326035 complement(2036186..2037676) 1 NC_013093.1 PFAM: Ricin B lectin; peptidase alpha-lytic pro domain; peptidase S1 and S6 chymotrypsin/Hap; SMART: Ricin B lectin; KEGG: mxa:MXAN_5466 peptidase, S1E (streptogrisin A) subfamily; Ricin B lectin 2037676 8326035 Amir_1850 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003099644.1 2036186 R 446462 CDS YP_003099645.1 256375985 8326036 complement(2037830..2038228) 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: dde:Dde_3083 glyoxalase family protein; glyoxalase/bleomycin resistance protein/dioxygenase 2038228 8326036 Amir_1851 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003099645.1 2037830 R 446462 CDS YP_003099646.1 256375986 8326037 complement(2038339..2039337) 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: aav:Aave_2249 inner membrane ABC transporter permease protein YjfF; Monosaccharide-transporting ATPase 2039337 8326037 Amir_1852 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003099646.1 2038339 R 446462 CDS YP_003099647.1 256375987 8326038 complement(2039334..2040305) 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: scl:sce3306 ribose/xylose/arabinose/galactoside ABC-type transporter permease; Monosaccharide-transporting ATPase 2040305 8326038 Amir_1853 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003099647.1 2039334 R 446462 CDS YP_003099648.1 256375988 8326039 complement(2040302..2041819) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bvi:Bcep1808_6551 ABC transporter; ABC transporter 2041819 8326039 Amir_1854 Actinosynnema mirum DSM 43827 ABC transporter YP_003099648.1 2040302 R 446462 CDS YP_003099649.1 256375989 8326040 complement(2042023..2043003) 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rpi:Rpic_4095 periplasmic binding protein/LacI transcriptional regulator; LacI family transcriptional regulator 2043003 8326040 Amir_1855 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099649.1 2042023 R 446462 CDS YP_003099650.1 256375990 8326041 2043266..2045485 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2045485 8326041 Amir_1856 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099650.1 2043266 D 446462 CDS YP_003099651.1 256375991 8326042 2045592..2048072 1 NC_013093.1 PFAM: alpha-L-arabinofuranosidase domain protein; carbohydrate-binding CenC domain protein; KEGG: ASD1; ASD1 (ALPHA-L-ARABINOFURANOSIDASE); hydrolase, acting on glycosyl bonds; alpha-N-arabinofuranosidase 2048072 8326042 Amir_1857 Actinosynnema mirum DSM 43827 alpha-N-arabinofuranosidase YP_003099651.1 2045592 D 446462 CDS YP_003099652.1 256375992 8326043 2048069..2049586 1 NC_013093.1 PFAM: glycoside hydrolase family 43; KEGG: hypothetical protein; alpha-N-arabinofuranosidase 2049586 8326043 Amir_1858 Actinosynnema mirum DSM 43827 alpha-N-arabinofuranosidase YP_003099652.1 2048069 D 446462 CDS YP_003099653.1 256375993 8326044 2049583..2051793 1 NC_013093.1 PFAM: protein of unknown function DUF1680; SMART: LamG domain protein jellyroll fold domain protein; KEGG: hypothetical protein; hypothetical protein 2051793 8326044 Amir_1859 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099653.1 2049583 D 446462 CDS YP_003099654.1 256375994 8326045 2051820..2052836 1 NC_013093.1 KEGG: scl:sce3317 HTH-type transcriptional repressor PurR; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 2052836 8326045 Amir_1860 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099654.1 2051820 D 446462 CDS YP_003099655.1 256375995 8326046 2053322..2054986 1 NC_013093.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 2054986 8326046 Amir_1861 Actinosynnema mirum DSM 43827 ribulokinase YP_003099655.1 2053322 D 446462 CDS YP_003099656.1 256375996 8326047 2054989..2055642 1 NC_013093.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate; L-ribulose-5-phosphate 4-epimerase 2055642 8326047 Amir_1862 Actinosynnema mirum DSM 43827 L-ribulose-5-phosphate 4-epimerase YP_003099656.1 2054989 D 446462 CDS YP_003099657.1 256375997 8326048 2055663..2057171 1 NC_013093.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 2057171 8326048 Amir_1863 Actinosynnema mirum DSM 43827 L-arabinose isomerase YP_003099657.1 2055663 D 446462 CDS YP_003099658.1 256375998 8326049 2057334..2058455 1 NC_013093.1 KEGG: rle:RL3617 solute-binding component of ABC transporter; ABC transporter solute-binding protein 2058455 8326049 Amir_1864 Actinosynnema mirum DSM 43827 ABC transporter solute-binding protein YP_003099658.1 2057334 D 446462 CDS YP_003099659.1 256375999 8326050 2058458..2059984 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH3441 L-arabinose ABC transporter ATP- binding protein; ABC transporter 2059984 8326050 Amir_1865 Actinosynnema mirum DSM 43827 ABC transporter YP_003099659.1 2058458 D 446462 CDS YP_003099660.1 256376000 8326051 2059981..2061198 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: bha:BH3440 L-arabinose ABC transporter (permease); inner-membrane translocator 2061198 8326051 Amir_1866 Actinosynnema mirum DSM 43827 inner-membrane translocator YP_003099660.1 2059981 D 446462 CDS YP_003099661.1 256376001 8326052 2061252..2062469 1 NC_013093.1 hypothetical protein 2062469 8326052 Amir_1867 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099661.1 2061252 D 446462 CDS YP_003099662.1 256376002 8326053 2062832..2065066 1 NC_013093.1 PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: cja:CJA_3559 rhamnogalacturonan lyase, rgl11A; cellulose-binding family protein 2065066 8326053 Amir_1868 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003099662.1 2062832 D 446462 CDS YP_003099663.1 256376003 8326054 2065200..2066354 1 NC_013093.1 SMART: Parallel beta-helix repeat; KEGG: scl:sce5350 secreted protein; parallel beta-helix repeat-containing protein 2066354 8326054 Amir_1869 Actinosynnema mirum DSM 43827 parallel beta-helix repeat-containing protein YP_003099663.1 2065200 D 446462 CDS YP_003099664.1 256376004 8326055 complement(2066451..2066780) 1 NC_013093.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: rme:Rmet_5441 antibiotic biosynthesis monooxygenase; Antibiotic biosynthesis monooxygenase 2066780 8326055 Amir_1870 Actinosynnema mirum DSM 43827 Antibiotic biosynthesis monooxygenase YP_003099664.1 2066451 R 446462 CDS YP_003099665.1 256376005 8326056 complement(2066879..2067880) 1 NC_013093.1 KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2067880 8326056 Amir_1871 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099665.1 2066879 R 446462 CDS YP_003099666.1 256376006 8326057 2068096..2071038 1 NC_013093.1 PFAM: alpha-L-arabinofuranosidase B; glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; KEGG: sus:Acid_6668 glycoside hydrolase family protein; alpha-L-arabinofuranosidase B 2071038 8326057 Amir_1872 Actinosynnema mirum DSM 43827 alpha-L-arabinofuranosidase B YP_003099666.1 2068096 D 446462 CDS YP_003099667.1 256376007 8326058 2071212..2074439 1 NC_013093.1 TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; KEGG: sml:Smlt2180 hypothetical protein; alpha-1,2-mannosidase 2074439 8326058 Amir_1873 Actinosynnema mirum DSM 43827 alpha-1,2-mannosidase YP_003099667.1 2071212 D 446462 CDS YP_003099668.1 256376008 8326059 2074586..2075710 1 NC_013093.1 KEGG: scl:sce2753 protein kinase; hypothetical protein 2075710 8326059 Amir_1874 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099668.1 2074586 D 446462 CDS YP_003099669.1 256376009 8326060 complement(2075861..2076955) 1 NC_013093.1 KEGG: dol:Dole_0415 filamentation induced by cAMP protein Fic; hypothetical protein 2076955 8326060 Amir_1875 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099669.1 2075861 R 446462 CDS YP_003099670.1 256376010 8326061 2076974..2077072 1 NC_013093.1 hypothetical protein 2077072 8326061 Amir_1876 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099670.1 2076974 D 446462 CDS YP_003099671.1 256376011 8326062 2077405..2078571 1 NC_013093.1 PFAM: endonuclease I; KEGG: bsu:BSU32540 hypothetical protein; endonuclease I 2078571 8326062 Amir_1877 Actinosynnema mirum DSM 43827 endonuclease I YP_003099671.1 2077405 D 446462 CDS YP_003099672.1 256376012 8326063 2078591..2078842 1 NC_013093.1 KEGG: hypothetical protein LOC100078772; hypothetical protein 2078842 8326063 Amir_1878 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099672.1 2078591 D 446462 CDS YP_003099673.1 256376013 8326064 2078839..2079945 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: vei:Veis_0031 multi-sensor signal transduction histidine kinase; signal transduction histidine kinase 2079945 8326064 Amir_1879 Actinosynnema mirum DSM 43827 signal transduction histidine kinase YP_003099673.1 2078839 D 446462 CDS YP_003099674.1 256376014 8326065 2079938..2081032 1 NC_013093.1 hypothetical protein 2081032 8326065 Amir_1880 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099674.1 2079938 D 446462 CDS YP_003099675.1 256376015 8326066 2081017..2081799 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: azo:azo0569 DNA-binding response regulator; LuxR family transcriptional regulator 2081799 8326066 Amir_1881 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099675.1 2081017 D 446462 CDS YP_003099676.1 256376016 8326067 2081952..2082611 1 NC_013093.1 KEGG: YALI0F00990p; hypothetical protein 2082611 8326067 Amir_1882 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099676.1 2081952 D 446462 CDS YP_003099677.1 256376017 8326068 2082682..2083647 1 NC_013093.1 KEGG: hch:HCH_00912 phosphoribosylpyrophosphate synthetase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; ribose-phosphate pyrophosphokinase 2083647 8326068 Amir_1883 Actinosynnema mirum DSM 43827 ribose-phosphate pyrophosphokinase YP_003099677.1 2082682 D 446462 CDS YP_003099678.1 256376018 8326069 complement(2083735..2085648) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: mrd:Mrad2831_1392 zinc finger SWIM domain- containing protein; hypothetical protein 2085648 8326069 Amir_1884 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099678.1 2083735 R 446462 CDS YP_003099679.1 256376019 8326070 complement(2085648..2086754) 1 NC_013093.1 PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor type A; KEGG: bur:Bcep18194_B1557 VWA containing CoxE-like protein; VWA containing CoxE family protein 2086754 8326070 Amir_1885 Actinosynnema mirum DSM 43827 VWA containing CoxE family protein YP_003099679.1 2085648 R 446462 CDS YP_003099680.1 256376020 8326071 complement(2086751..2089204) 1 NC_013093.1 KEGG: bur:Bcep18194_B1556 hypothetical protein; hypothetical protein 2089204 8326071 Amir_1886 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099680.1 2086751 R 446462 CDS YP_003099681.1 256376021 8326072 complement(2089204..2090295) 1 NC_013093.1 PFAM: ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: MoxR-like ATPase; ATPase 2090295 8326072 Amir_1887 Actinosynnema mirum DSM 43827 ATPase YP_003099681.1 2089204 R 446462 CDS YP_003099682.1 256376022 8326073 complement(2090462..2093761) 1 NC_013093.1 KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 2093761 8326073 Amir_1888 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099682.1 2090462 R 446462 CDS YP_003099683.1 256376023 8326074 complement(2093898..2097158) 1 NC_013093.1 KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 2097158 8326074 Amir_1889 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099683.1 2093898 R 446462 CDS YP_003099684.1 256376024 8326075 complement(2097267..2100581) 1 NC_013093.1 KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 2100581 8326075 Amir_1890 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099684.1 2097267 R 446462 CDS YP_003099685.1 256376025 8326076 complement(2100738..2101886) 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: bpt:Bpet2351 glycosyltransferase; group 1 glycosyl transferase 2101886 8326076 Amir_1891 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003099685.1 2100738 R 446462 CDS YP_003099686.1 256376026 8326077 2102119..2102532 1 NC_013093.1 PFAM: OsmC family protein; KEGG: bch:Bcen2424_5605 OsmC family protein; OsmC family protein 2102532 8326077 Amir_1892 Actinosynnema mirum DSM 43827 OsmC family protein YP_003099686.1 2102119 D 446462 CDS YP_003099687.1 256376027 8326078 complement(2102730..2103701) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2103701 8326078 Amir_1893 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099687.1 2102730 R 446462 CDS YP_003099688.1 256376028 8326079 complement(2103775..2105016) 1 NC_013093.1 KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein 2105016 8326079 Amir_1894 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099688.1 2103775 R 446462 CDS YP_003099689.1 256376029 8326080 2105269..2106297 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: sme:SMc01159 oxidoreductase protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2106297 8326080 Amir_1895 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003099689.1 2105269 D 446462 CDS YP_003099690.1 256376030 8326081 complement(2106355..2107893) 1 NC_013093.1 PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bbt:BBta_0011 UDP-N-acetylglucosamine 1- carboxyvinyltransferase; XRE family transcriptional regulator 2107893 8326081 Amir_1896 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003099690.1 2106355 R 446462 CDS YP_003099691.1 256376031 8326082 2108080..2108808 1 NC_013093.1 hypothetical protein 2108808 8326082 Amir_1897 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099691.1 2108080 D 446462 CDS YP_003099692.1 256376032 8326083 2108796..2109224 1 NC_013093.1 hypothetical protein 2109224 8326083 Amir_1898 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099692.1 2108796 D 446462 CDS YP_003099693.1 256376033 8326084 complement(2109279..2110241) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 4 domain protein; KEGG: bha:BH1376 RNA polymerase sigma factor RpoD; RpoD subfamily RNA polymerase sigma-70 subunit 2110241 8326084 Amir_1899 Actinosynnema mirum DSM 43827 RpoD subfamily RNA polymerase sigma-70 subunit YP_003099693.1 2109279 R 446462 CDS YP_003099694.1 256376034 8326085 complement(2110370..2111356) 1 NC_013093.1 PFAM: protein of unknown function DUF344; KEGG: tgr:Tgr7_0141 hypothetical protein; hypothetical protein 2111356 8326085 Amir_1900 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099694.1 2110370 R 446462 CDS YP_003099695.1 256376035 8326086 2111525..2111797 1 NC_013093.1 PFAM: transglycosylase-associated protein; KEGG: csa:Csal_2587 transglycosylase-associated protein; transglycosylase-associated protein 2111797 8326086 Amir_1901 Actinosynnema mirum DSM 43827 transglycosylase-associated protein YP_003099695.1 2111525 D 446462 CDS YP_003099696.1 256376036 8326087 2111981..2112085 1 NC_013093.1 hypothetical protein 2112085 8326087 Amir_1902 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099696.1 2111981 D 446462 CDS YP_003099697.1 256376037 8326088 complement(2112206..2112868) 1 NC_013093.1 KEGG: hch:HCH_06998 hypothetical protein; hypothetical protein 2112868 8326088 Amir_1903 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099697.1 2112206 R 446462 CDS YP_003099698.1 256376038 8326089 complement(2112879..2113637) 1 NC_013093.1 KEGG: acp:A2cp1_0343 hypothetical protein; hypothetical protein 2113637 8326089 Amir_1904 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099698.1 2112879 R 446462 CDS YP_003099699.1 256376039 8326090 2113793..2114803 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: sal:Sala_2455 alcohol dehydrogenase GroES- like protein; alcohol dehydrogenase GroES domain-containing protein 2114803 8326090 Amir_1905 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003099699.1 2113793 D 446462 CDS YP_003099700.1 256376040 8326091 complement(2114951..2116000) 1 NC_013093.1 PFAM: nitroreductase; KEGG: afw:Anae109_0827 hypothetical protein; nitroreductase 2116000 8326091 Amir_1906 Actinosynnema mirum DSM 43827 nitroreductase YP_003099700.1 2114951 R 446462 CDS YP_003099701.1 256376041 8326092 2116138..2117838 1 NC_013093.1 PFAM: GAF domain protein; histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: scl:sce2236 two-component system sensor kinase; GAF sensor signal transduction histidine kinase 2117838 8326092 Amir_1907 Actinosynnema mirum DSM 43827 GAF sensor signal transduction histidine kinase YP_003099701.1 2116138 D 446462 CDS YP_003099702.1 256376042 8326093 2117835..2118002 1 NC_013093.1 hypothetical protein 2118002 8326093 Amir_1908 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099702.1 2117835 D 446462 CDS YP_003099703.1 256376043 8326094 2117999..2118235 1 NC_013093.1 hypothetical protein 2118235 8326094 Amir_1909 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099703.1 2117999 D 446462 CDS YP_003099704.1 256376044 8326095 complement(2118365..2119021) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: bcy:Bcer98_0214 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 2119021 8326095 Amir_1910 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099704.1 2118365 R 446462 CDS YP_003099705.1 256376045 8326096 2119273..2119698 1 NC_013093.1 PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: pau:PA14_40540 CBS domain-containing protein; signal transduction protein with CBS domains 2119698 8326096 Amir_1911 Actinosynnema mirum DSM 43827 signal transduction protein with CBS domains YP_003099705.1 2119273 D 446462 CDS YP_003099706.1 256376046 8326097 2119914..2120381 1 NC_013093.1 PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 2120381 8326097 Amir_1912 Actinosynnema mirum DSM 43827 UspA domain-containing protein YP_003099706.1 2119914 D 446462 CDS YP_003099707.1 256376047 8326098 2120378..2122936 1 NC_013093.1 PFAM: CoA-binding domain protein; GCN5-related N- acetyltransferase; KEGG: mgm:Mmc1_1098 CoA-binding domain protein; CoA-binding domain-containing protein 2122936 8326098 Amir_1913 Actinosynnema mirum DSM 43827 CoA-binding domain-containing protein YP_003099707.1 2120378 D 446462 CDS YP_003099708.1 256376048 8326099 2122933..2123304 1 NC_013093.1 KEGG: aeh:Mlg_0315 UspA domain-containing protein; UspA domain-containing protein 2123304 8326099 Amir_1914 Actinosynnema mirum DSM 43827 UspA domain-containing protein YP_003099708.1 2122933 D 446462 CDS YP_003099709.1 256376049 8326100 2123369..2123767 1 NC_013093.1 KEGG: bbt:BBta_6725 hypothetical protein; hypothetical protein 2123767 8326100 Amir_1915 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099709.1 2123369 D 446462 CDS YP_003099710.1 256376050 8326101 complement(2123894..2124190) 1 NC_013093.1 hypothetical protein 2124190 8326101 Amir_1916 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099710.1 2123894 R 446462 CDS YP_003099711.1 256376051 8326102 complement(2124401..2125387) 1 NC_013093.1 PFAM: nitroreductase; KEGG: rce:RC1_3281 hypothetical protein; nitroreductase 2125387 8326102 Amir_1917 Actinosynnema mirum DSM 43827 nitroreductase YP_003099711.1 2124401 R 446462 CDS YP_003099712.1 256376052 8326103 2125566..2127935 1 NC_013093.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: bja:bll2518 phosphoketolase; phosphoketolase 2127935 8326103 Amir_1918 Actinosynnema mirum DSM 43827 phosphoketolase YP_003099712.1 2125566 D 446462 CDS YP_003099713.1 256376053 8326104 2127935..2129020 1 NC_013093.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: nwi:Nwi_1948 acetate kinase; acetate kinase 2129020 8326104 Amir_1919 Actinosynnema mirum DSM 43827 acetate kinase YP_003099713.1 2127935 D 446462 CDS YP_003099714.1 256376054 8326105 2129898..2130914 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: scl:sce5315 protein kinase; serine/threonine protein kinase 2130914 8326105 Amir_1920 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003099714.1 2129898 D 446462 CDS YP_003099715.1 256376055 8326106 2131354..2131851 1 NC_013093.1 hypothetical protein 2131851 8326106 Amir_1921 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099715.1 2131354 D 446462 CDS YP_003099716.1 256376056 8326107 2132284..2134341 1 NC_013093.1 PFAM: acyltransferase 3; KEGG: mes:Meso_0485 acyltransferase 3; acyltransferase 3 2134341 8326107 Amir_1922 Actinosynnema mirum DSM 43827 acyltransferase 3 YP_003099716.1 2132284 D 446462 CDS YP_003099717.1 256376057 8326108 2134527..2135327 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: ppd:Ppro_2693 glycosyl transferase family protein; family 2 glycosyl transferase 2135327 8326108 Amir_1923 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003099717.1 2134527 D 446462 CDS YP_003099718.1 256376058 8326109 2135399..2137411 1 NC_013093.1 PFAM: glycosyl transferase family 39; KEGG: bsu:BSU40490 hypothetical protein; glycosyl transferase family protein 2137411 8326109 Amir_1924 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003099718.1 2135399 D 446462 CDS YP_003099719.1 256376059 8326110 2137527..2138777 1 NC_013093.1 hypothetical protein 2138777 8326110 Amir_1925 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099719.1 2137527 D 446462 CDS YP_003099720.1 256376060 8326111 complement(2138797..2139831) 1 NC_013093.1 KEGG: pen:PSEEN1955 ribose operon repressor RbsR; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2139831 8326111 Amir_1926 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099720.1 2138797 R 446462 CDS YP_003099721.1 256376061 8326112 2140041..2141360 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: sugar ABC transporter; K10188 lactose/L- arabinose transport system substrate-binding protein; family 1 extracellular solute-binding protein 2141360 8326112 Amir_1927 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003099721.1 2140041 D 446462 CDS YP_003099722.1 256376062 8326113 2141357..2142253 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K10189 lactose/L- arabinose transport system permease protein; ABC transporter inner membrane protein 2142253 8326113 Amir_1928 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099722.1 2141357 D 446462 CDS YP_003099723.1 256376063 8326114 2142250..2143092 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sml:Smlt3250 sugar transporter, permease protein; ABC transporter inner membrane protein 2143092 8326114 Amir_1929 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099723.1 2142250 D 446462 CDS YP_003099724.1 256376064 8326115 2143103..2144605 1 NC_013093.1 PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: vei:Veis_3457 alpha-N-arabinofuranosidase; alpha-N-arabinofuranosidase 2144605 8326115 Amir_1930 Actinosynnema mirum DSM 43827 alpha-N-arabinofuranosidase YP_003099724.1 2143103 D 446462 CDS YP_003099725.1 256376065 8326116 complement(2145028..2145930) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; dTDP-4-dehydrorhamnose reductase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: glo:Glov_0487 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 2145930 8326116 Amir_1931 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003099725.1 2145028 R 446462 CDS YP_003099726.1 256376066 8326117 complement(2146023..2146454) 1 NC_013093.1 PFAM: cyclase/dehydrase; cyclase/dehydrase 2146454 8326117 Amir_1932 Actinosynnema mirum DSM 43827 cyclase/dehydrase YP_003099726.1 2146023 R 446462 CDS YP_003099727.1 256376067 8326118 complement(2146634..2147359) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcb:BCB4264_A5589 DNA-binding response regulator YycF; winged helix family two component transcriptional regulator 2147359 8326118 Amir_1933 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003099727.1 2146634 R 446462 CDS YP_003099728.1 256376068 8326119 2147431..2148255 1 NC_013093.1 PFAM: UspA domain protein; KEGG: afw:Anae109_3830 universal stress family protein; UspA domain-containing protein 2148255 8326119 Amir_1934 Actinosynnema mirum DSM 43827 UspA domain-containing protein YP_003099728.1 2147431 D 446462 CDS YP_003099729.1 256376069 8326120 2148302..2148736 1 NC_013093.1 PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 2148736 8326120 Amir_1935 Actinosynnema mirum DSM 43827 UspA domain-containing protein YP_003099729.1 2148302 D 446462 CDS YP_003099730.1 256376070 8326121 complement(2148805..2149110) 1 NC_013093.1 hypothetical protein 2149110 8326121 Amir_1936 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099730.1 2148805 R 446462 CDS YP_003099731.1 256376071 8326122 complement(2149252..2149857) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: xcv:XCV4086 LuxR family two-component response regulator; LuxR family transcriptional regulator 2149857 8326122 Amir_1937 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099731.1 2149252 R 446462 CDS YP_003099732.1 256376072 8326123 complement(2149854..2150945) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: ccs:CCNA_01207 two-component sensor histidine kinase; histidine kinase 2150945 8326123 Amir_1938 Actinosynnema mirum DSM 43827 histidine kinase YP_003099732.1 2149854 R 446462 CDS YP_003099733.1 256376073 8326124 complement(2150955..2151683) 1 NC_013093.1 PFAM: ABC transporter; KEGG: bca:BCE_5484 ABC transporter, permease protein; ABC transporter 2151683 8326124 Amir_1939 Actinosynnema mirum DSM 43827 ABC transporter YP_003099733.1 2150955 R 446462 CDS YP_003099734.1 256376074 8326125 complement(2151683..2152603) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ccs:CCNA_01205 ABC transporter ATP-binding protein; ABC transporter 2152603 8326125 Amir_1940 Actinosynnema mirum DSM 43827 ABC transporter YP_003099734.1 2151683 R 446462 CDS YP_003099735.1 256376075 8326126 2152700..2153098 1 NC_013093.1 KEGG: scl:sce6219 hypothetical protein; hypothetical protein 2153098 8326126 Amir_1941 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099735.1 2152700 D 446462 CDS YP_003099736.1 256376076 8326127 2153098..2153559 1 NC_013093.1 hypothetical protein 2153559 8326127 Amir_1942 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099736.1 2153098 D 446462 CDS YP_003099737.1 256376077 8326128 complement(2153564..2153731) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 2153731 8326128 Amir_1943 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099737.1 2153564 R 446462 CDS YP_003099738.1 256376078 8326129 complement(2153728..2154567) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: cko:CKO_01491 hypothetical protein; XRE family transcriptional regulator 2154567 8326129 Amir_1944 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003099738.1 2153728 R 446462 CDS YP_003099739.1 256376079 8326130 2154739..2155200 1 NC_013093.1 KEGG: chromosome segregation protein SMC; K03529 chromosome segregation protein; chromosome segregation protein SMC; K03529 chromosome segregation protein 2155200 8326130 Amir_1945 Actinosynnema mirum DSM 43827 chromosome segregation protein SMC; K03529 chromosome segregation protein YP_003099739.1 2154739 D 446462 CDS YP_003099740.1 256376080 8326131 2155252..2156100 1 NC_013093.1 KEGG: bpt:Bpet3209 spermidine synthase (putrescine aminopropyltransferase); spermidine synthase-like protein 2156100 8326131 Amir_1946 Actinosynnema mirum DSM 43827 spermidine synthase-like protein YP_003099740.1 2155252 D 446462 CDS YP_003099741.1 256376081 8326132 complement(2156270..2156977) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2156977 8326132 Amir_1947 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099741.1 2156270 R 446462 CDS YP_003099742.1 256376082 8326133 complement(2157127..2158161) 1 NC_013093.1 PFAM: ABC transporter; TOBE domain protein; SMART: ATPase AAA; KEGG: bac:BamMC406_1610 ABC transporter; ABC transporter 2158161 8326133 Amir_1948 Actinosynnema mirum DSM 43827 ABC transporter YP_003099742.1 2157127 R 446462 CDS YP_003099743.1 256376083 8326134 complement(2158158..2158937) 1 NC_013093.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; NifC-like ABC-type porter; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce1134 ABC-type molybdate transporter, permease protein; molybdate ABC transporter, inner membrane subunit 2158937 8326134 Amir_1949 Actinosynnema mirum DSM 43827 molybdate ABC transporter, inner membrane subunit YP_003099743.1 2158158 R 446462 CDS YP_003099744.1 256376084 8326135 complement(2158934..2159728) 1 NC_013093.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: scl:sce1135 ABC-type molybdate transporter, substrate-binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein 2159728 8326135 Amir_1950 Actinosynnema mirum DSM 43827 molybdenum ABC transporter periplasmic molybdate-binding protein YP_003099744.1 2158934 R 446462 CDS YP_003099745.1 256376085 8326136 complement(2159734..2160132) 1 NC_013093.1 TIGRFAM: DNA binding domain protein, excisionase family; PFAM: TOBE domain protein; regulatory protein MerR; KEGG: aba:Acid345_1548 molybdenum-pterin binding protein; excisionase family DNA binding domain-containing protein 2160132 8326136 Amir_1951 Actinosynnema mirum DSM 43827 excisionase family DNA binding domain-containing protein YP_003099745.1 2159734 R 446462 CDS YP_003099746.1 256376086 8326137 complement(2160337..2161062) 1 NC_013093.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: pst:PSPTO_2646 TetR family transcriptional regulator; TetR family transcriptional regulator 2161062 8326137 Amir_1952 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099746.1 2160337 R 446462 CDS YP_003099747.1 256376087 8326138 2161152..2162630 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: smt:Smal_2153 major facilitator superfamily MFS_1; major facilitator superfamily protein 2162630 8326138 Amir_1953 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099747.1 2161152 D 446462 CDS YP_003099748.1 256376088 8326139 complement(2162777..2164489) 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: hypothetical protein; LPXTG-motif cell wall anchor domain-containing protein 2164489 8326139 Amir_1954 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003099748.1 2162777 R 446462 CDS YP_003099749.1 256376089 8326140 2164726..2167434 1 NC_013093.1 PFAM: Osmosensitive K channel His kinase sensor; ATP-binding region ATPase domain protein; UspA domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mrd:Mrad2831_0205 osmosensitive K+ channel signal transduction histidine kinase; Osmosensitive K channel His kinase sensor 2167434 8326140 Amir_1955 Actinosynnema mirum DSM 43827 Osmosensitive K channel His kinase sensor YP_003099749.1 2164726 D 446462 CDS YP_003099750.1 256376090 8326141 2167526..2167864 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2167864 8326141 Amir_1956 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099750.1 2167526 D 446462 CDS YP_003099751.1 256376091 8326142 complement(2168094..2169128) 1 NC_013093.1 PFAM: PAS fold-3 domain protein; chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; PAC repeat- containing protein; KEGG: psp:PSPPH_4230 methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 2169128 8326142 Amir_1957 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003099751.1 2168094 R 446462 CDS YP_003099752.1 256376092 8326143 2169431..2169775 1 NC_013093.1 KEGG: rso:RS05496 oxidoreductase protein; hypothetical protein 2169775 8326143 Amir_1958 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099752.1 2169431 D 446462 CDS YP_003099753.1 256376093 8326144 complement(2169772..2170413) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: acr:Acry_0512 TetR family transcriptional regulator; TetR family transcriptional regulator 2170413 8326144 Amir_1959 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099753.1 2169772 R 446462 CDS YP_003099754.1 256376094 8326145 complement(2170502..2170702) 1 NC_013093.1 PFAM: protein of unknown function DUF1271; KEGG: bpy:Bphyt_4246 hypothetical protein; hypothetical protein 2170702 8326145 Amir_1960 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099754.1 2170502 R 446462 CDS YP_003099755.1 256376095 8326146 complement(2170914..2172113) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 2172113 8326146 Amir_1961 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003099755.1 2170914 R 446462 CDS YP_003099756.1 256376096 8326147 2172443..2173321 1 NC_013093.1 PFAM: Silent information regulator protein Sir2; KEGG: scl:sce3874 hypothetical protein; Silent information regulator protein Sir2 2173321 8326147 Amir_1962 Actinosynnema mirum DSM 43827 Silent information regulator protein Sir2 YP_003099756.1 2172443 D 446462 CDS YP_003099757.1 256376097 8326148 2173465..2173767 1 NC_013093.1 hypothetical protein 2173767 8326148 Amir_1963 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099757.1 2173465 D 446462 CDS YP_003099758.1 256376098 8326149 2173760..2175085 1 NC_013093.1 KEGG: mxa:MXAN_5876 hypothetical protein; hypothetical protein 2175085 8326149 Amir_1964 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099758.1 2173760 D 446462 CDS YP_003099759.1 256376099 8326150 2175082..2175981 1 NC_013093.1 hypothetical protein 2175981 8326150 Amir_1965 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099759.1 2175082 D 446462 CDS YP_003099760.1 256376100 8326151 2176506..2176961 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bra:BRADO0101 organic hydroperoxide resistance transcriptional regulator; MarR family transcriptional regulator 2176961 8326151 Amir_1966 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003099760.1 2176506 D 446462 CDS YP_003099761.1 256376101 8326152 2176958..2177356 1 NC_013093.1 hypothetical protein 2177356 8326152 Amir_1967 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099761.1 2176958 D 446462 CDS YP_003099762.1 256376102 8326153 complement(2177364..2178581) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: jan:Jann_0419 major facilitator transporter; major facilitator superfamily protein 2178581 8326153 Amir_1968 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099762.1 2177364 R 446462 CDS YP_003099763.1 256376103 8326154 complement(2178843..2179700) 1 NC_013093.1 KEGG: pmy:Pmen_4204 hypothetical protein; triacylglycerol lipase 2179700 8326154 Amir_1969 Actinosynnema mirum DSM 43827 triacylglycerol lipase YP_003099763.1 2178843 R 446462 CDS YP_003099764.1 256376104 8326155 2180087..2182594 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: acp:A2cp1_3940 hypothetical protein; LuxR family transcriptional regulator 2182594 8326155 Amir_1970 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099764.1 2180087 D 446462 CDS YP_003099765.1 256376105 8326156 2183048..2184484 1 NC_013093.1 PFAM: alpha-L-arabinofuranosidase B; glycosyl hydrolase family 32 domain protein; KEGG: scl:sce1247 hypothetical protein; alpha-L-arabinofuranosidase B 2184484 8326156 Amir_1971 Actinosynnema mirum DSM 43827 alpha-L-arabinofuranosidase B YP_003099765.1 2183048 D 446462 CDS YP_003099766.1 256376106 8326157 complement(2184597..2185208) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: aha:AHA_0553 TetR family transcriptional regulator; TetR family transcriptional regulator 2185208 8326157 Amir_1972 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099766.1 2184597 R 446462 CDS YP_003099767.1 256376107 8326158 complement(2185208..2186122) 1 NC_013093.1 PFAM: saccharopine dehydrogenase; KEGG: bha:BH3388 hypothetical protein; saccharopine dehydrogenase 2186122 8326158 Amir_1973 Actinosynnema mirum DSM 43827 saccharopine dehydrogenase YP_003099767.1 2185208 R 446462 CDS YP_003099768.1 256376108 8326159 complement(2186122..2186904) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: bja:bll4939 methyltransferase; type 11 methyltransferase 2186904 8326159 Amir_1974 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003099768.1 2186122 R 446462 CDS YP_003099769.1 256376109 8326160 2187099..2189051 1 NC_013093.1 PFAM: glycosyl hydrolase 67 middle domain protein; glycosyl hydrolase 67 C-teriminal domain protein; KEGG: bha:BH1061 alpha-glucuronidase; alpha-glucuronidase 2189051 8326160 Amir_1975 Actinosynnema mirum DSM 43827 alpha-glucuronidase YP_003099769.1 2187099 D 446462 CDS YP_003099770.1 256376110 8326161 complement(2189301..2191340) 1 NC_013093.1 PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; beta-galactosidase domain protein; KEGG: bha:BH3701 beta-galactosidase; beta-galactosidase 2191340 8326161 Amir_1976 Actinosynnema mirum DSM 43827 beta-galactosidase YP_003099770.1 2189301 R 446462 CDS YP_003099771.1 256376111 8326162 complement(2191337..2192023) 1 NC_013093.1 KEGG: afw:Anae109_4026 glycosyltransferase 36; glycosyl transferase family protein 2192023 8326162 Amir_1977 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003099771.1 2191337 R 446462 CDS YP_003099772.1 256376112 8326163 complement(2192020..2193558) 1 NC_013093.1 PFAM: glycoside hydrolase family 39; KEGG: bha:BH1068 beta-xylosidase; xylan 1,4-beta-xylosidase 2193558 8326163 Amir_1978 Actinosynnema mirum DSM 43827 xylan 1,4-beta-xylosidase YP_003099772.1 2192020 R 446462 CDS YP_003099773.1 256376113 8326164 complement(2193564..2195192) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_3560 AlgQ1, multiple sugar transport system substrate-binding protein; family 1 extracellular solute-binding protein 2195192 8326164 Amir_1979 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003099773.1 2193564 R 446462 CDS YP_003099774.1 256376114 8326165 complement(2195239..2196180) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bsu:BSU07120 transmembrane lipoprotein; ABC transporter inner membrane protein 2196180 8326165 Amir_1980 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099774.1 2195239 R 446462 CDS YP_003099775.1 256376115 8326166 complement(2196177..2197175) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_3564 AlgM1, multiple sugar transport system permease protein; ABC transporter inner membrane protein 2197175 8326166 Amir_1981 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099775.1 2196177 R 446462 CDS YP_003099776.1 256376116 8326167 complement(2197172..2199595) 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: vei:Veis_0942 glycoside hydrolase, family 3 domain protein; glycoside hydrolase family protein 2199595 8326167 Amir_1982 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003099776.1 2197172 R 446462 CDS YP_003099777.1 256376117 8326168 2199848..2200885 1 NC_013093.1 KEGG: rpi:Rpic_0879 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2200885 8326168 Amir_1983 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099777.1 2199848 D 446462 CDS YP_003099778.1 256376118 8326169 2201044..2202027 1 NC_013093.1 PFAM: acetyl xylan esterase; KEGG: mlo:mlr6993 acetyl xylan esterase; acetyl xylan esterase 2202027 8326169 Amir_1984 Actinosynnema mirum DSM 43827 acetyl xylan esterase YP_003099778.1 2201044 D 446462 CDS YP_003099779.1 256376119 8326170 complement(2202055..2202744) 1 NC_013093.1 PFAM: Clp domain protein; KEGG: ATP-dependent clp protease ATP-binding subunit; Clp domain-containing protein 2202744 8326170 Amir_1985 Actinosynnema mirum DSM 43827 Clp domain-containing protein YP_003099779.1 2202055 R 446462 CDS YP_003099780.1 256376120 8326171 complement(2202807..2203169) 1 NC_013093.1 KEGG: ank:AnaeK_3385 hypothetical protein; hypothetical protein 2203169 8326171 Amir_1986 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099780.1 2202807 R 446462 CDS YP_003099781.1 256376121 8326172 2203266..2204171 1 NC_013093.1 KEGG: scl:sce0848 protein kinase; hypothetical protein 2204171 8326172 Amir_1987 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099781.1 2203266 D 446462 CDS YP_003099782.1 256376122 8326173 complement(2204210..2204755) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: transcriptional regulator protein; TetR family transcriptional regulator 2204755 8326173 Amir_1988 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099782.1 2204210 R 446462 CDS YP_003099783.1 256376123 8326174 2205035..2205478 1 NC_013093.1 hypothetical protein 2205478 8326174 Amir_1989 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099783.1 2205035 D 446462 CDS YP_003099784.1 256376124 8326175 2205495..2206226 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: sme:SMc02722 aminoglycoside 3'- phosphotransferase protein; aminoglycoside phosphotransferase 2206226 8326175 Amir_1990 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003099784.1 2205495 D 446462 CDS YP_003099785.1 256376125 8326176 2206319..2206978 1 NC_013093.1 PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hypothetical protein; Haloacid dehalogenase domain-containing protein hydrolase 2206978 8326176 Amir_1991 Actinosynnema mirum DSM 43827 Haloacid dehalogenase domain-containing protein hydrolase YP_003099785.1 2206319 D 446462 CDS YP_003099786.1 256376126 8326177 complement(2207022..2207612) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2207612 8326177 Amir_1992 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099786.1 2207022 R 446462 CDS YP_003099787.1 256376127 8326178 complement(2207609..2208022) 1 NC_013093.1 PFAM: protein of unknown function DUF1469; KEGG: gbm:Gbem_1384 protein of unknown function DUF1469; hypothetical protein 2208022 8326178 Amir_1993 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099787.1 2207609 R 446462 CDS YP_003099788.1 256376128 8326179 2208120..2209040 1 NC_013093.1 TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN; KEGG: pfo:Pfl01_4350 ribonuclease BN; ribonuclease BN 2209040 8326179 Amir_1994 Actinosynnema mirum DSM 43827 ribonuclease BN YP_003099788.1 2208120 D 446462 CDS YP_003099789.1 256376129 8326180 complement(2209081..2210115) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; KEGG: scl:sce5062 hypothetical protein; alcohol dehydrogenase GroES domain-containing protein 2210115 8326180 Amir_1995 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003099789.1 2209081 R 446462 CDS YP_003099790.1 256376130 8326181 complement(2210124..2211428) 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: sat:SYN_01215 4-aminobutyrate aminotransferase; class III aminotransferase 2211428 8326181 Amir_1996 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003099790.1 2210124 R 446462 CDS YP_003099791.1 256376131 8326182 complement(2211428..2212984) 1 NC_013093.1 PFAM: glycosyl transferase family 20; KEGG: ank:AnaeK_0483 HAD-superfamily hydrolase, subfamily IIB; glycosyl transferase family protein 2212984 8326182 Amir_1997 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003099791.1 2211428 R 446462 CDS YP_003099792.1 256376132 8326183 complement(2213059..2213967) 1 NC_013093.1 PFAM: dTDP-4-dehydrorhamnose reductase; NAD- dependent epimerase/dehydratase; KEGG: acp:A2cp1_4446 dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 2213967 8326183 Amir_1998 Actinosynnema mirum DSM 43827 dTDP-4-dehydrorhamnose reductase YP_003099792.1 2213059 R 446462 CDS YP_003099793.1 256376133 8326184 complement(2214258..2215532) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: major facilitator superfamily MFS_1 precursor; major facilitator superfamily protein 2215532 8326184 Amir_1999 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099793.1 2214258 R 446462 CDS YP_003099794.1 256376134 8326185 2215644..2216792 1 NC_013093.1 PFAM: 3-dehydroquinate synthase; KEGG: reh:H16_A3434 3-dehydroquinate synthase; 3-dehydroquinate synthase 2216792 8326185 Amir_2000 Actinosynnema mirum DSM 43827 3-dehydroquinate synthase YP_003099794.1 2215644 D 446462 CDS YP_003099795.1 256376135 8326186 2216789..2218768 1 NC_013093.1 PFAM: xylose isomerase; ATPase BadF/BadG/BcrA/BcrD type; KEGG: vei:Veis_3268 xylose isomerase domain protein TIM barrel; xylose isomerase 2218768 8326186 Amir_2001 Actinosynnema mirum DSM 43827 xylose isomerase YP_003099795.1 2216789 D 446462 CDS YP_003099796.1 256376136 8326187 2218765..2219871 1 NC_013093.1 PFAM: Nucleotidyl transferase; KEGG: cja:CJA_3254 glucose-1-phosphate adenylyltransferase; Nucleotidyl transferase 2219871 8326187 Amir_2002 Actinosynnema mirum DSM 43827 Nucleotidyl transferase YP_003099796.1 2218765 D 446462 CDS YP_003099797.1 256376137 8326188 2219970..2220392 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3- methyltransferase; KEGG: lch:Lcho_1958 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2220392 8326188 Amir_2003 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003099797.1 2219970 D 446462 CDS YP_003099798.1 256376138 8326189 complement(2220429..2221010) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rle:RL2982 TetR family transcriptional regulator; TetR family transcriptional regulator 2221010 8326189 Amir_2004 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099798.1 2220429 R 446462 CDS YP_003099799.1 256376139 8326190 complement(2221163..2222728) 1 NC_013093.1 KEGG: rce:RC1_2688 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase; malate synthase A 2222728 8326190 Amir_2005 Actinosynnema mirum DSM 43827 malate synthase A YP_003099799.1 2221163 R 446462 CDS YP_003099800.1 256376140 8326191 complement(2222764..2224032) 1 NC_013093.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sml:Smlt0232 isocitrate lyase; isocitrate lyase 2224032 8326191 Amir_2006 Actinosynnema mirum DSM 43827 isocitrate lyase YP_003099800.1 2222764 R 446462 CDS YP_003099801.1 256376141 8326192 2224237..2225652 1 NC_013093.1 PFAM: protein of unknown function DUF955; helix- turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: rpt:Rpal_2644 transcriptional regulator, XRE family; XRE family transcriptional regulator 2225652 8326192 Amir_2007 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003099801.1 2224237 D 446462 CDS YP_003099802.1 256376142 8326193 complement(2225671..2226882) 1 NC_013093.1 KEGG: rec:RHECIAT_PC0000040 hypothetical protein; hypothetical protein 2226882 8326193 Amir_2008 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099802.1 2225671 R 446462 CDS YP_003099803.1 256376143 8326194 2227176..2228363 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 2228363 8326194 Amir_2009 Actinosynnema mirum DSM 43827 histidine kinase YP_003099803.1 2227176 D 446462 CDS YP_003099804.1 256376144 8326195 2228376..2229020 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 2229020 8326195 Amir_2010 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003099804.1 2228376 D 446462 CDS YP_003099805.1 256376145 8326196 2229169..2230050 1 NC_013093.1 KEGG: sfu:Sfum_3154 hypothetical protein; hypothetical protein 2230050 8326196 Amir_2011 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099805.1 2229169 D 446462 CDS YP_003099806.1 256376146 8326197 2230171..2231715 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 2231715 8326197 Amir_2012 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003099806.1 2230171 D 446462 CDS YP_003099807.1 256376147 8326198 2232011..2233438 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: scl:sce4973 monooxygenase; FAD-binding monooxygenase 2233438 8326198 Amir_2013 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003099807.1 2232011 D 446462 CDS YP_003099808.1 256376148 8326199 complement(2233468..2233887) 1 NC_013093.1 hypothetical protein 2233887 8326199 Amir_2014 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099808.1 2233468 R 446462 CDS YP_003099809.1 256376149 8326203 complement(2234529..2234954) 1 NC_013093.1 PFAM: sporulation and cell division protein SsgA; sporulation and cell division protein SsgA 2234954 8326203 Amir_2015 Actinosynnema mirum DSM 43827 sporulation and cell division protein SsgA YP_003099809.1 2234529 R 446462 CDS YP_003099810.1 256376150 8326204 2235175..2235852 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpi:Rpic_2575 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 2235852 8326204 Amir_2016 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003099810.1 2235175 D 446462 CDS YP_003099811.1 256376151 8326205 2235849..2236652 1 NC_013093.1 KEGG: GH10507 gene product from transcript GH10507- RA; hypothetical protein 2236652 8326205 Amir_2017 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099811.1 2235849 D 446462 CDS YP_003099812.1 256376152 8326206 2236667..2237086 1 NC_013093.1 KEGG: swp:swp_2864 hypothetical protein swp_2864; hypothetical protein 2237086 8326206 Amir_2018 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099812.1 2236667 D 446462 CDS YP_003099813.1 256376153 8326209 complement(2237988..2239670) 1 NC_013093.1 KEGG: bvi:Bcep1808_7197 integrase catalytic subunit; hypothetical protein 2239670 8326209 Amir_2020 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099813.1 2237988 R 446462 CDS YP_003099814.1 256376154 8326210 2240627..2241712 1 NC_013093.1 KEGG: bid:Bind_1964 non-specific serine/threonine protein kinase; scyllo-inosamine-4-phosphate amidinotransferase 2241712 8326210 Amir_2021 Actinosynnema mirum DSM 43827 scyllo-inosamine-4-phosphate amidinotransferase YP_003099814.1 2240627 D 446462 CDS YP_003099815.1 256376155 8326211 2241790..2243067 1 NC_013093.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 2243067 8326211 Amir_2022 Actinosynnema mirum DSM 43827 diaminobutyrate--2-oxoglutarate aminotransferase YP_003099815.1 2241790 D 446462 CDS YP_003099816.1 256376156 8326212 2243138..2243785 1 NC_013093.1 KEGG: rec:RHECIAT_PB0000363 hypothetical protein; hypothetical protein 2243785 8326212 Amir_2023 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099816.1 2243138 D 446462 CDS YP_003099817.1 256376157 8326213 2243782..2244681 1 NC_013093.1 PFAM: tryptophan 23-dioxygenase; KEGG: cak:Caul_5244 tryptophan 23-dioxygenase; tryptophan 23-dioxygenase 2244681 8326213 Amir_2024 Actinosynnema mirum DSM 43827 tryptophan 23-dioxygenase YP_003099817.1 2243782 D 446462 CDS YP_003099818.1 256376158 8326214 2244678..2245934 1 NC_013093.1 PFAM: aminotransferase class V; KEGG: swi:Swit_0679 kynureninase; class V aminotransferase 2245934 8326214 Amir_2025 Actinosynnema mirum DSM 43827 class V aminotransferase YP_003099818.1 2244678 D 446462 CDS YP_003099819.1 256376159 8326215 2245939..2247210 1 NC_013093.1 PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: bpd:BURPS668_0791 biotin carboxylase; ATP-dependent carboxylate-amine ligase domain-containing protein 2247210 8326215 Amir_2026 Actinosynnema mirum DSM 43827 ATP-dependent carboxylate-amine ligase domain-containing protein YP_003099819.1 2245939 D 446462 CDS YP_003099820.1 256376160 8326216 2247241..2248551 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: rpc:RPC_4715 major facilitator transporter; major facilitator superfamily protein 2248551 8326216 Amir_2027 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099820.1 2247241 D 446462 CDS YP_003099821.1 256376161 8326217 2248548..2249507 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bmb:BruAb2_0285 amino acid ABC transporter, periplasmic amino acid-binding protein; family 3 extracellular solute-binding protein 2249507 8326217 Amir_2028 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003099821.1 2248548 D 446462 CDS YP_003099822.1 256376162 8326218 2249565..2250950 1 NC_013093.1 PFAM: amino acid permease-associated region; KEGG: bur:Bcep18194_C7638 amino acid transporter; amino acid permease-associated protein 2250950 8326218 Amir_2029 Actinosynnema mirum DSM 43827 amino acid permease-associated protein YP_003099822.1 2249565 D 446462 CDS YP_003099823.1 256376163 8326219 2251035..2251259 1 NC_013093.1 hypothetical protein 2251259 8326219 Amir_2030 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099823.1 2251035 D 446462 CDS YP_003099824.1 256376164 8326220 2251483..2252985 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce7656 carbohydrate ABC transporter; ABC transporter 2252985 8326220 Amir_2031 Actinosynnema mirum DSM 43827 ABC transporter YP_003099824.1 2251483 D 446462 CDS YP_003099825.1 256376165 8326221 2252985..2253323 1 NC_013093.1 PFAM: peptidase S24 and S26 domain protein; KEGG: dal:Dalk_4340 signal peptidase I; peptidase S24 and S26 domain-containing protein 2253323 8326221 Amir_2032 Actinosynnema mirum DSM 43827 peptidase S24 and S26 domain-containing protein YP_003099825.1 2252985 D 446462 CDS YP_003099826.1 256376166 8326222 complement(2253269..2253634) 1 NC_013093.1 SMART: helix-turn-helix domain protein; addiction module antidote protein 2253634 8326222 Amir_2033 Actinosynnema mirum DSM 43827 addiction module antidote protein YP_003099826.1 2253269 R 446462 CDS YP_003099827.1 256376167 8326223 complement(2253976..2254980) 1 NC_013093.1 PFAM: integral membrane protein TerC; KEGG: ade:Adeh_2303 integral membrane protein TerC; integral membrane protein TerC 2254980 8326223 Amir_2034 Actinosynnema mirum DSM 43827 integral membrane protein TerC YP_003099827.1 2253976 R 446462 CDS YP_003099828.1 256376168 8326225 complement(2255481..2256647) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_0724 monooxygenase FAD-binding; FAD-binding monooxygenase 2256647 8326225 Amir_2036 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003099828.1 2255481 R 446462 CDS YP_003099829.1 256376169 8326226 complement(2256789..2257490) 1 NC_013093.1 KEGG: bcb:BCB4264_A2138 respiratory nitrate reductase, gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: nitrate reductase gamma subunit; respiratory nitrate reductase subunit gamma 2257490 8326226 Amir_2037 Actinosynnema mirum DSM 43827 respiratory nitrate reductase subunit gamma YP_003099829.1 2256789 R 446462 CDS YP_003099830.1 256376170 8326227 complement(2257487..2258110) 1 NC_013093.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: nitrate reductase delta subunit; KEGG: bsu:BSU37260 nitrate reductase (protein J); nitrate reductase molybdenum cofactor assembly chaperone 2258110 8326227 Amir_2038 Actinosynnema mirum DSM 43827 nitrate reductase molybdenum cofactor assembly chaperone YP_003099830.1 2257487 R 446462 CDS YP_003099831.1 256376171 8326228 complement(2258107..2259642) 1 NC_013093.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: bsu:BSU37270 nitrate reductase (beta subunit); nitrate reductase subunit beta 2259642 8326228 Amir_2039 Actinosynnema mirum DSM 43827 nitrate reductase subunit beta YP_003099831.1 2258107 R 446462 CDS YP_003099832.1 256376172 8326229 complement(2259642..2263310) 1 NC_013093.1 KEGG: bcb:BCB4264_A2135 respiratory nitrate reductase, alpha subunit; TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; nitrate reductase subunit alpha 2263310 8326229 Amir_2040 Actinosynnema mirum DSM 43827 nitrate reductase subunit alpha YP_003099832.1 2259642 R 446462 CDS YP_003099833.1 256376173 8326230 2263420..2264613 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_2929 major facilitator transporter; major facilitator superfamily protein 2264613 8326230 Amir_2041 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099833.1 2263420 D 446462 CDS YP_003099834.1 256376174 8326231 complement(2264785..2265213) 1 NC_013093.1 KEGG: bcm:Bcenmc03_1697 hypothetical protein; hypothetical protein 2265213 8326231 Amir_2042 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099834.1 2264785 R 446462 CDS YP_003099835.1 256376175 8326232 complement(2265267..2265959) 1 NC_013093.1 hypothetical protein 2265959 8326232 Amir_2043 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099835.1 2265267 R 446462 CDS YP_003099836.1 256376176 8326233 complement(2266002..2266223) 1 NC_013093.1 hypothetical protein 2266223 8326233 Amir_2044 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099836.1 2266002 R 446462 CDS YP_003099837.1 256376177 8326234 2266370..2266543 1 NC_013093.1 hypothetical protein 2266543 8326234 Amir_2045 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099837.1 2266370 D 446462 CDS YP_003099838.1 256376178 8326235 2266727..2268172 1 NC_013093.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 2268172 8326235 Amir_2046 Actinosynnema mirum DSM 43827 argininosuccinate synthase YP_003099838.1 2266727 D 446462 CDS YP_003099839.1 256376179 8326236 complement(2268249..2270828) 1 NC_013093.1 PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; KEGG: hypothetical protein; alpha-L-rhamnosidase 2270828 8326236 Amir_2047 Actinosynnema mirum DSM 43827 alpha-L-rhamnosidase YP_003099839.1 2268249 R 446462 CDS YP_003099840.1 256376180 8326237 complement(2271015..2273054) 1 NC_013093.1 PFAM: cellulose-binding family II; Fibronectin type III domain protein; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: cak:Caul_2415 alpha-N-arabinofuranosidase; cellulose-binding family protein 2273054 8326237 Amir_2048 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003099840.1 2271015 R 446462 CDS YP_003099841.1 256376181 8326238 complement(2273320..2274330) 1 NC_013093.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: pst:PSPTO_4577 glycine betaine/choline OpuC ABC transporter, periplasmic substrate-binding protein; glycine/betaine ABC transporter substrate-binding protein 2274330 8326238 Amir_2049 Actinosynnema mirum DSM 43827 glycine/betaine ABC transporter substrate-binding protein YP_003099841.1 2273320 R 446462 CDS YP_003099842.1 256376182 8326239 complement(2274327..2275103) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bsu:BSU33720 choline ABC transporter membrane protein; ABC transporter inner membrane protein 2275103 8326239 Amir_2050 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099842.1 2274327 R 446462 CDS YP_003099843.1 256376183 8326240 complement(2275100..2276212) 1 NC_013093.1 KEGG: pol:Bpro_1154 glycine betaine/L-proline transport ATP binding subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; glycine betaine/L-proline ABC transporter ATPase subunit 2276212 8326240 Amir_2051 Actinosynnema mirum DSM 43827 glycine betaine/L-proline ABC transporter ATPase subunit YP_003099843.1 2275100 R 446462 CDS YP_003099844.1 256376184 8326241 complement(2276202..2276852) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1467 inner-membrane permease; ABC transporter inner membrane protein 2276852 8326241 Amir_2052 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099844.1 2276202 R 446462 CDS YP_003099845.1 256376185 8326242 complement(2277242..2277880) 1 NC_013093.1 KEGG: gsu:GSU0139 hypothetical protein; hypothetical protein 2277880 8326242 Amir_2053 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099845.1 2277242 R 446462 CDS YP_003099846.1 256376186 8326243 2278287..2279423 1 NC_013093.1 KEGG: acr:Acry_0984 extracellular solute-binding protein; extracellular solute-binding protein 2279423 8326243 Amir_2054 Actinosynnema mirum DSM 43827 extracellular solute-binding protein YP_003099846.1 2278287 D 446462 CDS YP_003099847.1 256376187 8326244 2279427..2280338 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: acr:Acry_0983 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2280338 8326244 Amir_2055 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099847.1 2279427 D 446462 CDS YP_003099848.1 256376188 8326245 2280329..2281144 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_1679 ABC transporter permease; ABC transporter inner membrane protein 2281144 8326245 Amir_2056 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099848.1 2280329 D 446462 CDS YP_003099849.1 256376189 8326246 2281146..2282231 1 NC_013093.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: acr:Acry_0981 ABC transporter; ABC transporter 2282231 8326246 Amir_2057 Actinosynnema mirum DSM 43827 ABC transporter YP_003099849.1 2281146 D 446462 CDS YP_003099850.1 256376190 8326247 complement(2282315..2283757) 1 NC_013093.1 KEGG: sus:Acid_3131 secreted protein; hypothetical protein 2283757 8326247 Amir_2058 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099850.1 2282315 R 446462 CDS YP_003099851.1 256376191 8326248 2283961..2284587 1 NC_013093.1 PFAM: protein of unknown function DUF305; KEGG: eli:ELI_14360 secreted protein; hypothetical protein 2284587 8326248 Amir_2059 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099851.1 2283961 D 446462 CDS YP_003099852.1 256376192 8326249 complement(2284777..2285037) 1 NC_013093.1 hypothetical protein 2285037 8326249 Amir_2060 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099852.1 2284777 R 446462 CDS YP_003099853.1 256376193 8326250 complement(2285251..2285727) 1 NC_013093.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sus:Acid_2535 guanine deaminase; zinc-binding CMP/dCMP deaminase 2285727 8326250 Amir_2061 Actinosynnema mirum DSM 43827 zinc-binding CMP/dCMP deaminase YP_003099853.1 2285251 R 446462 CDS YP_003099854.1 256376194 8326251 complement(2285820..2286116) 1 NC_013093.1 TIGRFAM: hydroxyisourate hydrolase; PFAM: transthyretin; KEGG: hypothetical protein; hydroxyisourate hydrolase 2286116 8326251 Amir_2062 Actinosynnema mirum DSM 43827 hydroxyisourate hydrolase YP_003099854.1 2285820 R 446462 CDS YP_003099855.1 256376195 8326252 2286271..2287956 1 NC_013093.1 PFAM: purine catabolism PurC domain protein; KEGG: GK24882 gene product from transcript GK24882- RA; PucR family transcriptional regulator 2287956 8326252 Amir_2063 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003099855.1 2286271 D 446462 CDS YP_003099856.1 256376196 8326253 2288071..2289039 1 NC_013093.1 KEGG: aav:Aave_4523 superoxide dismutase; superoxide dismutase 2289039 8326253 Amir_2064 Actinosynnema mirum DSM 43827 superoxide dismutase YP_003099856.1 2288071 D 446462 CDS YP_003099857.1 256376197 8326254 2289064..2289165 1 NC_013093.1 hypothetical protein 2289165 8326254 Amir_2065 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099857.1 2289064 D 446462 CDS YP_003099858.1 256376198 8326255 2289272..2291728 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: lch:Lcho_0275 histidine kinase; ATP-binding region ATPase domain-containing protein 2291728 8326255 Amir_2066 Actinosynnema mirum DSM 43827 ATP-binding region ATPase domain-containing protein YP_003099858.1 2289272 D 446462 CDS YP_003099859.1 256376199 8326256 2291773..2292201 1 NC_013093.1 PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_2813 roadblock/LC7 family protein; Roadblock/LC7 family protein 2292201 8326256 Amir_2067 Actinosynnema mirum DSM 43827 Roadblock/LC7 family protein YP_003099859.1 2291773 D 446462 CDS YP_003099860.1 256376200 8326257 2292198..2292566 1 NC_013093.1 PFAM: protein of unknown function DUF742; hypothetical protein 2292566 8326257 Amir_2068 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099860.1 2292198 D 446462 CDS YP_003099861.1 256376201 8326258 2292547..2293140 1 NC_013093.1 PFAM: protein of unknown function ATP binding; KEGG: dac:Daci_0776 protein of unknown function ATP binding; hypothetical protein 2293140 8326258 Amir_2069 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099861.1 2292547 D 446462 CDS YP_003099862.1 256376202 8326259 complement(2293141..2294439) 1 NC_013093.1 PFAM: flavin-containing monooxygenase FMO; FAD- dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pla:Plav_0443 flavin-containing monooxygenase; flavin-containing monooxygenase 2294439 8326259 Amir_2070 Actinosynnema mirum DSM 43827 flavin-containing monooxygenase YP_003099862.1 2293141 R 446462 CDS YP_003099863.1 256376203 8326260 2294631..2295752 1 NC_013093.1 KEGG: met:M446_0097 hypothetical protein; hypothetical protein 2295752 8326260 Amir_2071 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099863.1 2294631 D 446462 CDS YP_003099864.1 256376204 8326261 2295899..2296483 1 NC_013093.1 PFAM: protein of unknown function UPF0157; KEGG: mxa:MXAN_5238 hypothetical protein; hypothetical protein 2296483 8326261 Amir_2072 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099864.1 2295899 D 446462 CDS YP_003099865.1 256376205 8326262 complement(2296533..2297393) 1 NC_013093.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: gbm:Gbem_1461 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxybutyryl-CoA dehydrogenase 2297393 8326262 Amir_2073 Actinosynnema mirum DSM 43827 3-hydroxybutyryl-CoA dehydrogenase YP_003099865.1 2296533 R 446462 CDS YP_003099866.1 256376206 8326263 complement(2297519..2298187) 1 NC_013093.1 PFAM: SCP-like extracellular; KEGG: noc:Noc_1373 hypothetical protein; SCP-like extracellular 2298187 8326263 Amir_2074 Actinosynnema mirum DSM 43827 SCP-like extracellular YP_003099866.1 2297519 R 446462 CDS YP_003099867.1 256376207 8326264 complement(2298286..2299701) 1 NC_013093.1 TIGRFAM: ethanolamine transproter; PFAM: amino acid permease-associated region; KEGG: ppg:PputGB1_0589 ethanolamine transproter; ethanolamine transporter 2299701 8326264 Amir_2075 Actinosynnema mirum DSM 43827 ethanolamine transporter YP_003099867.1 2298286 R 446462 CDS YP_003099868.1 256376208 8326265 2299823..2301187 1 NC_013093.1 PFAM: glutamine synthetase catalytic region; KEGG: acr:Acry_2393 glutamine synthetase, catalytic region; glutamate--ammonia ligase 2301187 8326265 Amir_2076 Actinosynnema mirum DSM 43827 glutamate--ammonia ligase YP_003099868.1 2299823 D 446462 CDS YP_003099869.1 256376209 8326266 2301168..2301869 1 NC_013093.1 PFAM: peptidase C26; glutamine amidotransferase class-I; KEGG: rru:Rru_A0651 glutamine amidotransferase class-I; peptidase C26 2301869 8326266 Amir_2077 Actinosynnema mirum DSM 43827 peptidase C26 YP_003099869.1 2301168 D 446462 CDS YP_003099870.1 256376210 8326267 2301866..2303224 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: swi:Swit_1745 aldehyde dehydrogenase (acceptor); aldehyde dehydrogenase 2303224 8326267 Amir_2078 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003099870.1 2301866 D 446462 CDS YP_003099871.1 256376211 8326268 2303283..2304050 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: hypothetical protein; short chain dehydrogenase 2304050 8326268 Amir_2079 Actinosynnema mirum DSM 43827 short chain dehydrogenase YP_003099871.1 2303283 D 446462 CDS YP_003099872.1 256376212 8326269 2304064..2304765 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; Helix-turn-helix type 11 domain protein; SMART: regulatory protein GntR HTH; KEGG: swi:Swit_1674 GntR family transcriptional regulator; GntR family transcriptional regulator 2304765 8326269 Amir_2080 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003099872.1 2304064 D 446462 CDS YP_003099873.1 256376213 8326270 2304836..2305597 1 NC_013093.1 KEGG: bav:BAV1541 competence protein; hypothetical protein 2305597 8326270 Amir_2081 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099873.1 2304836 D 446462 CDS YP_003099874.1 256376214 8326271 2305594..2306076 1 NC_013093.1 hypothetical protein 2306076 8326271 Amir_2082 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099874.1 2305594 D 446462 CDS YP_003099875.1 256376215 8326272 2306154..2306657 1 NC_013093.1 KEGG: ank:AnaeK_2798 response regulator receiver; response regulator receiver 2306657 8326272 Amir_2083 Actinosynnema mirum DSM 43827 response regulator receiver YP_003099875.1 2306154 D 446462 CDS YP_003099876.1 256376216 8326273 2306785..2307630 1 NC_013093.1 KEGG: saz:Sama_0820 lipoprotein; hypothetical protein 2307630 8326273 Amir_2084 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099876.1 2306785 D 446462 CDS YP_003099877.1 256376217 8326274 2307658..2308614 1 NC_013093.1 KEGG: acp:A2cp1_4055 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; daunorubicin ABC transporter ATPase 2308614 8326274 Amir_2085 Actinosynnema mirum DSM 43827 daunorubicin ABC transporter ATPase YP_003099877.1 2307658 D 446462 CDS YP_003099878.1 256376218 8326275 2308611..2309414 1 NC_013093.1 PFAM: ABC transporter; KEGG: bcz:BCZK3149 ABC transporter efflux permease; daunorubicin resistance transmembrane protein; daunorubicin ABC transporter transmembrane protein 2309414 8326275 Amir_2086 Actinosynnema mirum DSM 43827 daunorubicin ABC transporter transmembrane protein YP_003099878.1 2308611 D 446462 CDS YP_003099879.1 256376219 8326276 complement(2309460..2309666) 1 NC_013093.1 hypothetical protein 2309666 8326276 Amir_2087 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099879.1 2309460 R 446462 CDS YP_003099880.1 256376220 8326278 2310424..2312472 1 NC_013093.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2312472 thrS 8326278 thrS Actinosynnema mirum DSM 43827 threonyl-tRNA synthetase YP_003099880.1 2310424 D 446462 CDS YP_003099881.1 256376221 8326279 2312469..2313017 1 NC_013093.1 PFAM: histidine triad (HIT) protein; KEGG: pca:Pcar_1504 HIT (HINT, histidine triad) family protein; histidine triad (HIT) protein 2313017 8326279 Amir_2090 Actinosynnema mirum DSM 43827 histidine triad (HIT) protein YP_003099881.1 2312469 D 446462 CDS YP_003099882.1 256376222 8326280 2313814..2314575 1 NC_013093.1 hypothetical protein 2314575 8326280 Amir_2091 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099882.1 2313814 D 446462 CDS YP_003099883.1 256376223 8326281 2314637..2315284 1 NC_013093.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: noc:Noc_2982 CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase 2315284 8326281 Amir_2092 Actinosynnema mirum DSM 43827 CDP-alcohol phosphatidyltransferase YP_003099883.1 2314637 D 446462 CDS YP_003099884.1 256376224 8326282 2315281..2316213 1 NC_013093.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 2316213 8326282 Amir_2093 Actinosynnema mirum DSM 43827 lipid A biosynthesis lauroyl acyltransferase YP_003099884.1 2315281 D 446462 CDS YP_003099885.1 256376225 8326283 2316210..2317337 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: acp:A2cp1_4300 phosphatidylinositol alpha- mannosyltransferase; phosphatidylinositol alpha-mannosyltransferase 2317337 8326283 Amir_2094 Actinosynnema mirum DSM 43827 phosphatidylinositol alpha-mannosyltransferase YP_003099885.1 2316210 D 446462 CDS YP_003099886.1 256376226 8326284 2317334..2318317 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: pzu:PHZ_c0948 mutator MutT protein; NUDIX hydrolase 2318317 8326284 Amir_2095 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003099886.1 2317334 D 446462 CDS YP_003099887.1 256376227 8326285 complement(2318395..2318772) 1 NC_013093.1 PFAM: protein of unknown function DUF1696; KEGG: vpa:VPA1559 hypothetical protein; hypothetical protein 2318772 8326285 Amir_2096 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099887.1 2318395 R 446462 CDS YP_003099888.1 256376228 8326286 complement(2318920..2319465) 1 NC_013093.1 hypothetical protein 2319465 8326286 Amir_2097 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099888.1 2318920 R 446462 CDS YP_003099889.1 256376229 8326287 complement(2319462..2320454) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: pde:Pden_1120 luciferase family protein; luciferase-like monooxygenase 2320454 8326287 Amir_2098 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003099889.1 2319462 R 446462 CDS YP_003099890.1 256376230 8326288 complement(2320465..2321856) 1 NC_013093.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 2321856 8326288 Amir_2099 Actinosynnema mirum DSM 43827 phenylhydantoinase YP_003099890.1 2320465 R 446462 CDS YP_003099891.1 256376231 8326289 complement(2321853..2322695) 1 NC_013093.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sus:Acid_7663 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase 2322695 8326289 Amir_2100 Actinosynnema mirum DSM 43827 nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase YP_003099891.1 2321853 R 446462 CDS YP_003099892.1 256376232 8326290 complement(2322692..2324194) 1 NC_013093.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sus:Acid_7658 NCS1 nucleoside transporter; NCS1 nucleoside transporter family 2324194 8326290 Amir_2101 Actinosynnema mirum DSM 43827 NCS1 nucleoside transporter family YP_003099892.1 2322692 R 446462 CDS YP_003099893.1 256376233 8326291 2324545..2324808 1 NC_013093.1 hypothetical protein 2324808 8326291 Amir_2102 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099893.1 2324545 D 446462 CDS YP_003099894.1 256376234 8326292 complement(2324805..2326415) 1 NC_013093.1 PFAM: purine catabolism PurC domain protein; KEGG: pag:PLES_34081 regulatory protein; PucR family transcriptional regulator 2326415 8326292 Amir_2103 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003099894.1 2324805 R 446462 CDS YP_003099895.1 256376235 8326293 2326533..2327825 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: sus:Acid_7662 aminotransferase; class III aminotransferase 2327825 8326293 Amir_2104 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003099895.1 2326533 D 446462 CDS YP_003099896.1 256376236 8326294 2327822..2329363 1 NC_013093.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: sus:Acid_0680 methylmalonate-semialdehyde dehydrogenase [acylating]; methylmalonate-semialdehyde dehydrogenase 2329363 8326294 Amir_2105 Actinosynnema mirum DSM 43827 methylmalonate-semialdehyde dehydrogenase YP_003099896.1 2327822 D 446462 CDS YP_003099897.1 256376237 8326295 2329561..2329875 1 NC_013093.1 hypothetical protein 2329875 8326295 Amir_2106 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099897.1 2329561 D 446462 CDS YP_003099898.1 256376238 8326296 complement(2330391..2332616) 1 NC_013093.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2332616 8326296 Amir_2107 Actinosynnema mirum DSM 43827 elongation factor G YP_003099898.1 2330391 R 446462 CDS YP_003099899.1 256376239 8326297 2332890..2333858 1 NC_013093.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 2333858 8326297 Amir_2108 Actinosynnema mirum DSM 43827 pyridoxal biosynthesis lyase PdxS YP_003099899.1 2332890 D 446462 CDS YP_003099900.1 256376240 8326298 2334894..2335508 1 NC_013093.1 PFAM: SNO glutamine amidotransferase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: dds:Ddes_1897 SNO glutamine amidotransferase; SNO glutamine amidotransferase 2335508 8326298 Amir_2109 Actinosynnema mirum DSM 43827 SNO glutamine amidotransferase YP_003099900.1 2334894 D 446462 CDS YP_003099901.1 256376241 8326299 2335528..2336283 1 NC_013093.1 PFAM: protein of unknown function DUF28; KEGG: gme:Gmet_0743 hypothetical protein; hypothetical protein 2336283 8326299 Amir_2110 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099901.1 2335528 D 446462 CDS YP_003099902.1 256376242 8326300 2336341..2336868 1 NC_013093.1 KEGG: pna:Pnap_0373 hypothetical protein; hypothetical protein 2336868 8326300 Amir_2111 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099902.1 2336341 D 446462 CDS YP_003099903.1 256376243 8326301 complement(2337013..2337546) 1 NC_013093.1 hypothetical protein 2337546 8326301 Amir_2112 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099903.1 2337013 R 446462 CDS YP_003099904.1 256376244 8326302 complement(2337641..2338189) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: smt:Smal_2152 transcriptional regulator, TetR family; TetR family transcriptional regulator 2338189 8326302 Amir_2113 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099904.1 2337641 R 446462 CDS YP_003099905.1 256376245 8326303 complement(2338211..2339716) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: smt:Smal_2153 major facilitator superfamily MFS_1; major facilitator superfamily protein 2339716 8326303 Amir_2114 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099905.1 2338211 R 446462 CDS YP_003099906.1 256376246 8326304 complement(2339992..2341284) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: mrd:Mrad2831_3880 cytochrome P450; cytochrome P450 2341284 8326304 Amir_2115 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003099906.1 2339992 R 446462 CDS YP_003099907.1 256376247 8326305 complement(2341316..2342485) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: pag:PLES_17331 cytochrome P450; cytochrome P450 2342485 8326305 Amir_2116 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003099907.1 2341316 R 446462 CDS YP_003099908.1 256376248 8326306 2342700..2343788 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: sus:Acid_6248 TetR family transcriptional regulator; TetR family transcriptional regulator 2343788 8326306 Amir_2117 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099908.1 2342700 D 446462 CDS YP_003099909.1 256376249 8326307 complement(2344146..2344607) 1 NC_013093.1 PFAM: thioesterase superfamily protein; KEGG: mxa:MXAN_4456 thioesterase family protein; thioesterase superfamily protein 2344607 8326307 Amir_2118 Actinosynnema mirum DSM 43827 thioesterase superfamily protein YP_003099909.1 2344146 R 446462 CDS YP_003099910.1 256376250 8326308 complement(2344618..2345778) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: nmu:Nmul_A1807 hypothetical protein; major facilitator superfamily protein 2345778 8326308 Amir_2119 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003099910.1 2344618 R 446462 CDS YP_003099911.1 256376251 8326309 complement(2345948..2346544) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: azo:azo0243 TetR family transcriptional regulator; TetR family transcriptional regulator 2346544 8326309 Amir_2120 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003099911.1 2345948 R 446462 CDS YP_003099912.1 256376252 8326310 2346699..2347658 1 NC_013093.1 KEGG: hypothetical protein LOC761802; hypothetical protein 2347658 8326310 Amir_2121 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099912.1 2346699 D 446462 CDS YP_003099913.1 256376253 8326311 2347740..2348966 1 NC_013093.1 PFAM: glutamate--cysteine ligase GCS2; KEGG: acp:A2cp1_3936 glutamate--cysteine ligase; glutamate--cysteine ligase GCS2 2348966 8326311 Amir_2122 Actinosynnema mirum DSM 43827 glutamate--cysteine ligase GCS2 YP_003099913.1 2347740 D 446462 CDS YP_003099914.1 256376254 8326312 2349328..2350656 1 NC_013093.1 PFAM: protein of unknown function DUF323; KEGG: mxa:MXAN_7471 hypothetical protein; hypothetical protein 2350656 8326312 Amir_2123 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099914.1 2349328 D 446462 CDS YP_003099915.1 256376255 8326313 2350657..2351415 1 NC_013093.1 KEGG: mch:Mchl_5354 glutamine amidotransferase class-II; glutamine amidotransferase 2351415 8326313 Amir_2124 Actinosynnema mirum DSM 43827 glutamine amidotransferase YP_003099915.1 2350657 D 446462 CDS YP_003099916.1 256376256 8326314 2351412..2352374 1 NC_013093.1 TIGRFAM: methyltransferase; KEGG: mxa:MXAN_7473 hypothetical protein; methyltransferase 2352374 8326314 Amir_2125 Actinosynnema mirum DSM 43827 methyltransferase YP_003099916.1 2351412 D 446462 CDS YP_003099917.1 256376257 8326315 complement(2352448..2352675) 1 NC_013093.1 hypothetical protein 2352675 8326315 Amir_2126 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099917.1 2352448 R 446462 CDS YP_003099918.1 256376258 8326316 2352944..2353807 1 NC_013093.1 SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 2353807 8326316 Amir_2127 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003099918.1 2352944 D 446462 CDS YP_003099919.1 256376259 8326317 2353820..2354014 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 2354014 8326317 Amir_2128 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099919.1 2353820 D 446462 CDS YP_003099920.1 256376260 8326318 complement(2354410..2354622) 1 NC_013093.1 hypothetical protein 2354622 8326318 Amir_2129 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099920.1 2354410 R 446462 CDS YP_003099921.1 256376261 8326319 2354869..2355252 1 NC_013093.1 PFAM: peptidoglycan-binding domain 1 protein; peptidoglycan-binding domain 1 protein 2355252 8326319 Amir_2130 Actinosynnema mirum DSM 43827 peptidoglycan-binding domain 1 protein YP_003099921.1 2354869 D 446462 CDS YP_003099922.1 256376262 8326320 2355321..2355695 1 NC_013093.1 PFAM: peptidoglycan-binding domain 1 protein; KEGG: mes:Meso_0085 peptidoglycan-binding domain 1; peptidoglycan-binding domain 1 protein 2355695 8326320 Amir_2131 Actinosynnema mirum DSM 43827 peptidoglycan-binding domain 1 protein YP_003099922.1 2355321 D 446462 CDS YP_003099923.1 256376263 8326321 complement(2355760..2358585) 1 NC_013093.1 TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: eba:ebA6773 aconitate hydratase; aconitate hydratase 1 2358585 8326321 Amir_2132 Actinosynnema mirum DSM 43827 aconitate hydratase 1 YP_003099923.1 2355760 R 446462 CDS YP_003099924.1 256376264 8326322 2358831..2359667 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bat:BAS4648 ABC transporter, ATP-binding protein; ABC transporter 2359667 8326322 Amir_2133 Actinosynnema mirum DSM 43827 ABC transporter YP_003099924.1 2358831 D 446462 CDS YP_003099925.1 256376265 8326323 2359664..2360314 1 NC_013093.1 KEGG: bce:BC4749 ABC transporter permease protein; hypothetical protein 2360314 8326323 Amir_2134 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099925.1 2359664 D 446462 CDS YP_003099926.1 256376266 8326324 2360379..2360837 1 NC_013093.1 KEGG: ade:Adeh_3822 AraC family transcriptional regulator; AraC family transcriptional regulator 2360837 8326324 Amir_2135 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003099926.1 2360379 D 446462 CDS YP_003099927.1 256376267 8326325 complement(2360848..2362002) 1 NC_013093.1 KEGG: bch:Bcen2424_6766 PE-PGRS family protein; hypothetical protein 2362002 8326325 Amir_2136 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099927.1 2360848 R 446462 CDS YP_003099928.1 256376268 8326326 2362104..2362868 1 NC_013093.1 PFAM: Silent information regulator protein Sir2; KEGG: sat:SYN_00042 sir2 family protein; Silent information regulator protein Sir2 2362868 8326326 Amir_2137 Actinosynnema mirum DSM 43827 Silent information regulator protein Sir2 YP_003099928.1 2362104 D 446462 CDS YP_003099929.1 256376269 8326327 2362949..2363524 1 NC_013093.1 PFAM: carbonic anhydrase; KEGG: xau:Xaut_2228 carbonate dehydratase; carbonic anhydrase 2363524 8326327 Amir_2138 Actinosynnema mirum DSM 43827 carbonic anhydrase YP_003099929.1 2362949 D 446462 CDS YP_003099930.1 256376270 8326328 2363636..2365168 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sus:Acid_7357 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 2365168 8326328 Amir_2139 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003099930.1 2363636 D 446462 CDS YP_003099931.1 256376271 8326329 2365302..2366585 1 NC_013093.1 PFAM: NLP/P60 protein; KEGG: NlpC/P60-like cell-wall peptidase; NLP/P60 protein 2366585 8326329 Amir_2140 Actinosynnema mirum DSM 43827 NLP/P60 protein YP_003099931.1 2365302 D 446462 CDS YP_003099932.1 256376272 8326330 2366708..2367310 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: mmr:Mmar10_0581 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 2367310 8326330 Amir_2141 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003099932.1 2366708 D 446462 CDS YP_003099933.1 256376273 8326331 2367373..2367750 1 NC_013093.1 KEGG: rle:RL0353 transmembrane transport protein; transmembrane transport protein 2367750 8326331 Amir_2142 Actinosynnema mirum DSM 43827 transmembrane transport protein YP_003099933.1 2367373 D 446462 CDS YP_003099934.1 256376274 8326332 complement(2368599..2369147) 1 NC_013093.1 KEGG: pfl:PFL_3722 molybdopterin-guanine dinucleotide biosynthesis protein A; molybdopterin-guanine dinucleotide biosynthesis protein A 2369147 8326332 Amir_2143 Actinosynnema mirum DSM 43827 molybdopterin-guanine dinucleotide biosynthesis protein A YP_003099934.1 2368599 R 446462 CDS YP_003099935.1 256376275 8326333 complement(2369297..2369941) 1 NC_013093.1 PFAM: thiopurine S-methyltransferase; KEGG: psa:PST_2541 thiopurine S-methyltransferase; Thiopurine S-methyltransferase 2369941 8326333 Amir_2144 Actinosynnema mirum DSM 43827 Thiopurine S-methyltransferase YP_003099935.1 2369297 R 446462 CDS YP_003099936.1 256376276 8326334 2370097..2371137 1 NC_013093.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: reh:H16_B1613 MoxR-like ATPase; ATPase 2371137 8326334 Amir_2145 Actinosynnema mirum DSM 43827 ATPase YP_003099936.1 2370097 D 446462 CDS YP_003099937.1 256376277 8326335 2371185..2372189 1 NC_013093.1 PFAM: protein of unknown function DUF58; KEGG: pna:Pnap_3246 protein of unknown function DUF58; hypothetical protein 2372189 8326335 Amir_2146 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099937.1 2371185 D 446462 CDS YP_003099938.1 256376278 8326336 2372189..2373154 1 NC_013093.1 PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: azo:azo2864 hypothetical protein; hypothetical protein 2373154 8326336 Amir_2147 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099938.1 2372189 D 446462 CDS YP_003099939.1 256376279 8326337 2373151..2373723 1 NC_013093.1 KEGG: swp:swp_0140 hypothetical protein; hypothetical protein 2373723 8326337 Amir_2148 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099939.1 2373151 D 446462 CDS YP_003099940.1 256376280 8326338 complement(2373734..2374621) 1 NC_013093.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: psa:PST_4124 periplasmic binding protein; TRAP transporter solute receptor, TAXI family 2374621 8326338 Amir_2149 Actinosynnema mirum DSM 43827 TRAP transporter solute receptor, TAXI family YP_003099940.1 2373734 R 446462 CDS YP_003099941.1 256376281 8326339 complement(2374618..2375988) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: scl:sce7107 sensor histidine kinase; histidine kinase 2375988 8326339 Amir_2150 Actinosynnema mirum DSM 43827 histidine kinase YP_003099941.1 2374618 R 446462 CDS YP_003099942.1 256376282 8326340 complement(2375993..2376646) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: afw:Anae109_0880 two component transcriptional regulator; winged helix family two component transcriptional regulator 2376646 8326340 Amir_2151 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003099942.1 2375993 R 446462 CDS YP_003099943.1 256376283 8326341 2376701..2377435 1 NC_013093.1 PFAM: ANTAR domain protein; GAF domain protein; SMART: GAF domain protein; KEGG: sus:Acid_4463 GAF sensor protein; ANTAR domain-containing protein with unknown sensor 2377435 8326341 Amir_2152 Actinosynnema mirum DSM 43827 ANTAR domain-containing protein with unknown sensor YP_003099943.1 2376701 D 446462 CDS YP_003099944.1 256376284 8326342 2377876..2378334 1 NC_013093.1 KEGG: dvm:DvMF_1072 hypothetical protein; hypothetical protein 2378334 8326342 Amir_2153 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099944.1 2377876 D 446462 CDS YP_003099945.1 256376285 8326343 complement(2378381..2379298) 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: maq:Maqu_2160 hypothetical protein; LPXTG-motif cell wall anchor domain-containing protein 2379298 8326343 Amir_2154 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003099945.1 2378381 R 446462 CDS YP_003099946.1 256376286 8326344 complement(2379375..2380637) 1 NC_013093.1 KEGG: maq:Maqu_2160 hypothetical protein; hypothetical protein 2380637 8326344 Amir_2155 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099946.1 2379375 R 446462 CDS YP_003099947.1 256376287 8326345 2380880..2381521 1 NC_013093.1 KEGG: maq:Maqu_2160 hypothetical protein; hypothetical protein 2381521 8326345 Amir_2156 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099947.1 2380880 D 446462 CDS YP_003099948.1 256376288 8326346 2381678..2382757 1 NC_013093.1 TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: bph:Bphy_2768 hypothetical protein; virulence factor Mce family protein 2382757 8326346 Amir_2157 Actinosynnema mirum DSM 43827 virulence factor Mce family protein YP_003099948.1 2381678 D 446462 CDS YP_003099949.1 256376289 8326347 2382757..2383785 1 NC_013093.1 TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sfu:Sfum_0474 mammalian cell entry related domain protein; virulence factor Mce family protein 2383785 8326347 Amir_2158 Actinosynnema mirum DSM 43827 virulence factor Mce family protein YP_003099949.1 2382757 D 446462 CDS YP_003099950.1 256376290 8326348 2383782..2384747 1 NC_013093.1 TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: gme:Gmet_1272 virulence factor MCE-like protein-related protein; virulence factor Mce family protein 2384747 8326348 Amir_2159 Actinosynnema mirum DSM 43827 virulence factor Mce family protein YP_003099950.1 2383782 D 446462 CDS YP_003099951.1 256376291 8326349 2384747..2385751 1 NC_013093.1 TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sat:SYN_00409 ABC-type transport system involved in resistance to organic solvents, periplasmic component; virulence factor Mce family protein 2385751 8326349 Amir_2160 Actinosynnema mirum DSM 43827 virulence factor Mce family protein YP_003099951.1 2384747 D 446462 CDS YP_003099952.1 256376292 8326350 2385748..2386737 1 NC_013093.1 TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sat:SYN_00409 ABC-type transport system involved in resistance to organic solvents, periplasmic component; virulence factor Mce family protein 2386737 8326350 Amir_2161 Actinosynnema mirum DSM 43827 virulence factor Mce family protein YP_003099952.1 2385748 D 446462 CDS YP_003099953.1 256376293 8326351 2386743..2387789 1 NC_013093.1 TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sat:SYN_00409 ABC-type transport system involved in resistance to organic solvents, periplasmic component; virulence factor Mce family protein 2387789 8326351 Amir_2162 Actinosynnema mirum DSM 43827 virulence factor Mce family protein YP_003099953.1 2386743 D 446462 CDS YP_003099954.1 256376294 8326352 2387893..2388432 1 NC_013093.1 hypothetical protein 2388432 8326352 Amir_2163 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099954.1 2387893 D 446462 CDS YP_003099955.1 256376295 8326353 2388640..2389527 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: bra:BRADO6829 phosphotransferase; aminoglycoside phosphotransferase 2389527 8326353 Amir_2164 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003099955.1 2388640 D 446462 CDS YP_003099956.1 256376296 8326354 complement(2389532..2389900) 1 NC_013093.1 KEGG: tgr:Tgr7_1062 sec-C motif domain protein; sec-C motif domain-containing protein 2389900 8326354 Amir_2165 Actinosynnema mirum DSM 43827 sec-C motif domain-containing protein YP_003099956.1 2389532 R 446462 CDS YP_003099957.1 256376297 8326355 complement(2389972..2391369) 1 NC_013093.1 KEGG: mxa:MXAN_4837 endoglucanase; PFAM: glycoside hydrolase family 6; cellulose- binding family II; SMART: cellulose-binding family II; Cellulase 2391369 8326355 Amir_2166 Actinosynnema mirum DSM 43827 Cellulase YP_003099957.1 2389972 R 446462 CDS YP_003099958.1 256376298 8326356 2392660..2395584 1 NC_013093.1 PFAM: glycoside hydrolase family 48; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: hch:HCH_02465 RTX toxins and related Ca2+- binding protein; glycoside hydrolase family protein 2395584 8326356 Amir_2167 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003099958.1 2392660 D 446462 CDS YP_003099959.1 256376299 8326357 2395750..2398377 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: bha:BH1908 glucan 1,4-beta-glucosidase; beta-glucosidase 2398377 8326357 Amir_2168 Actinosynnema mirum DSM 43827 beta-glucosidase YP_003099959.1 2395750 D 446462 CDS YP_003099960.1 256376300 8326358 2398377..2399390 1 NC_013093.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bam:Bamb_4929 LacI family transcription regulator; LacI family transcriptional regulator 2399390 8326358 Amir_2169 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003099960.1 2398377 D 446462 CDS YP_003099961.1 256376301 8326359 2399697..2401295 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH0482 lipoprotein; family 1 extracellular solute-binding protein 2401295 8326359 Amir_2170 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003099961.1 2399697 D 446462 CDS YP_003099962.1 256376302 8326360 2401282..2402256 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH0484 transmembrane lipoprotein; ABC transporter inner membrane protein 2402256 8326360 Amir_2171 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099962.1 2401282 D 446462 CDS YP_003099963.1 256376303 8326361 2402253..2403218 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bsu:BSU30170 hypothetical protein; ABC transporter inner membrane protein 2403218 8326361 Amir_2172 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003099963.1 2402253 D 446462 CDS YP_003099964.1 256376304 8326362 2403256..2405238 1 NC_013093.1 PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; beta-galactosidase domain protein; KEGG: bha:BH3701 beta-galactosidase; beta-galactosidase 2405238 8326362 Amir_2173 Actinosynnema mirum DSM 43827 beta-galactosidase YP_003099964.1 2403256 D 446462 CDS YP_003099965.1 256376305 8326363 2405213..2407153 1 NC_013093.1 KEGG: xcv:XCV1806 hypothetical protein; hypothetical protein 2407153 8326363 Amir_2174 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099965.1 2405213 D 446462 CDS YP_003099966.1 256376306 8326364 2407165..2407473 1 NC_013093.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: bbr:BB0060 periplasmic divalent cation tolerance protein; CutA1 divalent ion tolerance protein 2407473 8326364 Amir_2175 Actinosynnema mirum DSM 43827 CutA1 divalent ion tolerance protein YP_003099966.1 2407165 D 446462 CDS YP_003099967.1 256376307 8326365 2407562..2407939 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: gur:Gura_3524 MerR family transcriptional regulator; MerR family transcriptional regulator 2407939 8326365 Amir_2176 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003099967.1 2407562 D 446462 CDS YP_003099968.1 256376308 8326366 complement(2408010..2408375) 1 NC_013093.1 hypothetical protein 2408375 8326366 Amir_2177 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099968.1 2408010 R 446462 CDS YP_003099969.1 256376309 8326367 complement(2408563..2409540) 1 NC_013093.1 PFAM: beta-lactamase; KEGG: bcj:BCAM2165 beta-lactamase, class A; beta-lactamase 2409540 8326367 Amir_2178 Actinosynnema mirum DSM 43827 beta-lactamase YP_003099969.1 2408563 R 446462 CDS YP_003099970.1 256376310 8326368 complement(2409598..2412282) 1 NC_013093.1 PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: ade:Adeh_0810 hypothetical protein; FAD linked oxidase domain-containing protein 2412282 8326368 Amir_2179 Actinosynnema mirum DSM 43827 FAD linked oxidase domain-containing protein YP_003099970.1 2409598 R 446462 CDS YP_003099971.1 256376311 8326369 2412409..2413113 1 NC_013093.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: prw:PsycPRwf_0457 3-oxoacyl-(acyl-carrier- protein) reductase; 3-oxoacyl-(acyl-carrier-protein) reductase 2413113 8326369 Amir_2180 Actinosynnema mirum DSM 43827 3-oxoacyl-(acyl-carrier-protein) reductase YP_003099971.1 2412409 D 446462 CDS YP_003099972.1 256376312 8326370 2413178..2413945 1 NC_013093.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 2413945 8326370 Amir_2181 Actinosynnema mirum DSM 43827 enoyl-(acyl carrier protein) reductase YP_003099972.1 2413178 D 446462 CDS YP_003099973.1 256376313 8326371 2414041..2415075 1 NC_013093.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 2415075 hemH 8326371 hemH Actinosynnema mirum DSM 43827 ferrochelatase YP_003099973.1 2414041 D 446462 CDS YP_003099974.1 256376314 8326372 2415072..2415737 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2415737 8326372 Amir_2183 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099974.1 2415072 D 446462 CDS YP_003099975.1 256376315 8326373 2415795..2416568 1 NC_013093.1 KEGG: bph:Bphy_2507 hypothetical protein; hypothetical protein 2416568 8326373 Amir_2184 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099975.1 2415795 D 446462 CDS YP_003099976.1 256376316 8326374 complement(2416673..2417386) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: hne:HNE_0018 short chain dehydrogenase/reductase family oxidoreductase; short-chain dehydrogenase/reductase SDR 2417386 8326374 Amir_2185 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003099976.1 2416673 R 446462 CDS YP_003099977.1 256376317 8326375 2417793..2418407 1 NC_013093.1 KEGG: BSM; submaxillary mucin 2; hypothetical protein 2418407 8326375 Amir_2186 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099977.1 2417793 D 446462 CDS YP_003099978.1 256376318 8326376 2418667..2419101 1 NC_013093.1 hypothetical protein 2419101 8326376 Amir_2187 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099978.1 2418667 D 446462 CDS YP_003099979.1 256376319 8326377 2419098..2419709 1 NC_013093.1 hypothetical protein 2419709 8326377 Amir_2188 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099979.1 2419098 D 446462 CDS YP_003099980.1 256376320 8326378 2419713..2421077 1 NC_013093.1 KEGG: GH21940 gene product from transcript GH21940- RA; hypothetical protein 2421077 8326378 Amir_2189 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099980.1 2419713 D 446462 CDS YP_003099981.1 256376321 8326379 2421169..2421963 1 NC_013093.1 hypothetical protein 2421963 8326379 Amir_2190 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099981.1 2421169 D 446462 CDS YP_003099982.1 256376322 8326380 2422379..2424196 1 NC_013093.1 PFAM: glycoside hydrolase family 6; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: sde:Sde_2272 cellobiohydrolase A (1 4-beta- cellobiosidase A)-like; glycoside hydrolase family protein 2424196 8326380 Amir_2191 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003099982.1 2422379 D 446462 CDS YP_003099983.1 256376323 8326381 2424621..2426006 1 NC_013093.1 KEGG: sus:Acid_2208 magnesium protoporphyrin chelatase; magnesium protoporphyrin chelatase 2426006 8326381 Amir_2192 Actinosynnema mirum DSM 43827 magnesium protoporphyrin chelatase YP_003099983.1 2424621 D 446462 CDS YP_003099984.1 256376324 8326382 2426003..2427949 1 NC_013093.1 SMART: von Willebrand factor type A; KEGG: aba:Acid345_3257 von Willebrand factor, type A; von Willebrand factor type A 2427949 8326382 Amir_2193 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003099984.1 2426003 D 446462 CDS YP_003099985.1 256376325 8326383 complement(2427952..2429133) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: GA27442 gene product from transcript GA27442- RA; ECF subfamily RNA polymerase sigma-24 subunit 2429133 8326383 Amir_2194 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003099985.1 2427952 R 446462 CDS YP_003099986.1 256376326 8326384 complement(2429225..2429695) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA2974 MutT-like protein; NUDIX hydrolase 2429695 8326384 Amir_2195 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003099986.1 2429225 R 446462 CDS YP_003099987.1 256376327 8326386 complement(2430700..2432268) 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 2432268 8326386 Amir_2197 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003099987.1 2430700 R 446462 CDS YP_003099988.1 256376328 8326387 complement(2432446..2434215) 1 NC_013093.1 KEGG: bha:BH2614 cytochrome Caa3 oxidase (subunit I); TIGRFAM: cytochrome C oxidase, subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase, subunit I 2434215 8326387 Amir_2198 Actinosynnema mirum DSM 43827 cytochrome C oxidase, subunit I YP_003099988.1 2432446 R 446462 CDS YP_003099989.1 256376329 8326390 2436340..2437578 1 NC_013093.1 KEGG: afw:Anae109_2496 cysteinyl-tRNA synthetase; TIGRFAM: cysteine/1-D-myo-inosityl 2-amino-2-deoxy- alpha-D-glucopyranoside ligase; PFAM: Cysteinyl-tRNA synthetase class Ia; cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase 2437578 8326390 Amir_2201 Actinosynnema mirum DSM 43827 cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase YP_003099989.1 2436340 D 446462 CDS YP_003099990.1 256376330 8326391 complement(2437727..2439520) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proprotein convertase P; Ig family protein; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 2439520 8326391 Amir_2202 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003099990.1 2437727 R 446462 CDS YP_003099991.1 256376331 8326392 complement(2439721..2440173) 1 NC_013093.1 KEGG: scl:sce6114 hypothetical protein; hypothetical protein 2440173 8326392 Amir_2203 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099991.1 2439721 R 446462 CDS YP_003099992.1 256376332 8326393 2440558..2441238 1 NC_013093.1 KEGG: sus:Acid_6164 Ig family protein; hypothetical protein 2441238 8326393 Amir_2204 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099992.1 2440558 D 446462 CDS YP_003099993.1 256376333 8326394 2441280..2441819 1 NC_013093.1 KEGG: similar to glycoprotein (predicted); hypothetical protein 2441819 8326394 Amir_2205 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099993.1 2441280 D 446462 CDS YP_003099994.1 256376334 8326395 2441816..2442745 1 NC_013093.1 TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24 and S26 domain protein; KEGG: similar to trefoil factor; peptidase S26B, signal peptidase 2442745 8326395 Amir_2206 Actinosynnema mirum DSM 43827 peptidase S26B, signal peptidase YP_003099994.1 2441816 D 446462 CDS YP_003099995.1 256376335 8326396 2442742..2443476 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dvm:DvMF_0882 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 2443476 8326396 Amir_2207 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003099995.1 2442742 D 446462 CDS YP_003099996.1 256376336 8326397 2443473..2443877 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: aba:Acid345_3504 response regulator receiver protein; response regulator receiver protein 2443877 8326397 Amir_2208 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003099996.1 2443473 D 446462 CDS YP_003099997.1 256376337 8326398 complement(2443831..2445030) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein; GAF sensor signal transduction histidine kinase 2445030 8326398 Amir_2209 Actinosynnema mirum DSM 43827 GAF sensor signal transduction histidine kinase YP_003099997.1 2443831 R 446462 CDS YP_003099998.1 256376338 8326399 complement(2445326..2446222) 1 NC_013093.1 PFAM: protein of unknown function DUF75; KEGG: sfu:Sfum_3209 hypothetical protein; hypothetical protein 2446222 8326399 Amir_2210 Actinosynnema mirum DSM 43827 hypothetical protein YP_003099998.1 2445326 R 446462 CDS YP_003099999.1 256376339 8326400 2446273..2449809 1 NC_013093.1 TIGRFAM: methionine synthase; PFAM: homocysteine S-methyltransferase; methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; dihydropteroate synthase DHPS; vitamin B12 dependent methionine synthase activation region; KEGG: gdi:GDI3502 methionine synthase; methionine synthase 2449809 8326400 Amir_2211 Actinosynnema mirum DSM 43827 methionine synthase YP_003099999.1 2446273 D 446462 CDS YP_003100000.1 256376340 8326401 2449922..2450584 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: smt:Smal_0452 HAD-superfamily hydrolase, subfamily IA, variant 3; HAD superfamily hydrolase 2450584 8326401 Amir_2212 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003100000.1 2449922 D 446462 CDS YP_003100001.1 256376341 8326402 complement(2450603..2451280) 1 NC_013093.1 PFAM: ferric iron reductase; KEGG: aav:Aave_3725 ferric iron reductase protein FhuF; ferric iron reductase 2451280 8326402 Amir_2213 Actinosynnema mirum DSM 43827 ferric iron reductase YP_003100001.1 2450603 R 446462 CDS YP_003100002.1 256376342 8326403 complement(2451273..2451860) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: acr:Acry_3038 TetR family transcriptional regulator; TetR family transcriptional regulator 2451860 8326403 Amir_2214 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100002.1 2451273 R 446462 CDS YP_003100003.1 256376343 8326404 2451964..2453187 1 NC_013093.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pag:PLES_23881 FMN oxidoreductase; NADH:flavin oxidoreductase/NADH oxidase 2453187 8326404 Amir_2215 Actinosynnema mirum DSM 43827 NADH:flavin oxidoreductase/NADH oxidase YP_003100003.1 2451964 D 446462 CDS YP_003100004.1 256376344 8326405 2453184..2453984 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: pau:PA14_08440 short chain alcohol dehydrogenase; short-chain dehydrogenase/reductase SDR 2453984 8326405 Amir_2216 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100004.1 2453184 D 446462 CDS YP_003100005.1 256376345 8326406 2454077..2454523 1 NC_013093.1 KEGG: sdn:Sden_0673 hypothetical protein; hypothetical protein 2454523 8326406 Amir_2217 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100005.1 2454077 D 446462 CDS YP_003100006.1 256376346 8326407 2454564..2454845 1 NC_013093.1 TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: xfn:XfasM23_1346 phosphoribosyl-ATP diphosphatase; phosphoribosyl-ATP diphosphatase 2454845 8326407 Amir_2218 Actinosynnema mirum DSM 43827 phosphoribosyl-ATP diphosphatase YP_003100006.1 2454564 D 446462 CDS YP_003100007.1 256376347 8326408 2454877..2455815 1 NC_013093.1 PFAM: auxin Efflux Carrier; KEGG: dvm:DvMF_1323 auxin efflux carrier; auxin Efflux Carrier 2455815 8326408 Amir_2219 Actinosynnema mirum DSM 43827 auxin Efflux Carrier YP_003100007.1 2454877 D 446462 CDS YP_003100008.1 256376348 8326410 complement(2456832..2457602) 1 NC_013093.1 KEGG: smt:Smal_1417 hypothetical protein; hypothetical protein 2457602 8326410 Amir_2221 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100008.1 2456832 R 446462 CDS YP_003100009.1 256376349 8326411 complement(2457731..2458624) 1 NC_013093.1 KEGG: hypothetical protein; RecB family exonuclease-like protein 2458624 8326411 Amir_2222 Actinosynnema mirum DSM 43827 RecB family exonuclease-like protein YP_003100009.1 2457731 R 446462 CDS YP_003100010.1 256376350 8326412 2458685..2459815 1 NC_013093.1 PFAM: peptidase M50; KEGG: aeh:Mlg_1368 peptidase M50; peptidase M50 2459815 8326412 Amir_2223 Actinosynnema mirum DSM 43827 peptidase M50 YP_003100010.1 2458685 D 446462 CDS YP_003100011.1 256376351 8326414 complement(2460547..2461176) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 2461176 8326414 Amir_2225 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100011.1 2460547 R 446462 CDS YP_003100012.1 256376352 8326415 complement(2461212..2462324) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 2462324 8326415 Amir_2226 Actinosynnema mirum DSM 43827 histidine kinase YP_003100012.1 2461212 R 446462 CDS YP_003100013.1 256376353 8326416 2462436..2462978 1 NC_013093.1 KEGG: bat:BAS2996 hypothetical protein; hypothetical protein 2462978 8326416 Amir_2227 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100013.1 2462436 D 446462 CDS YP_003100014.1 256376354 8326417 2463053..2463880 1 NC_013093.1 PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: sfu:Sfum_2514 SAM-dependent methyltransferase; tRNA methyltransferase complex GCD14 subunit 2463880 8326417 Amir_2228 Actinosynnema mirum DSM 43827 tRNA methyltransferase complex GCD14 subunit YP_003100014.1 2463053 D 446462 CDS YP_003100015.1 256376355 8326418 complement(2463949..2464839) 1 NC_013093.1 KEGG: scl:sce5792 hypothetical protein; hypothetical protein 2464839 8326418 Amir_2229 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100015.1 2463949 R 446462 CDS YP_003100016.1 256376356 8326419 complement(2465044..2466003) 1 NC_013093.1 KEGG: scl:sce5792 hypothetical protein; hypothetical protein 2466003 8326419 Amir_2230 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100016.1 2465044 R 446462 CDS YP_003100017.1 256376357 8326420 2466722..2468521 1 NC_013093.1 PFAM: ATPase AAA; SMART: ATPase AAA; KEGG: gur:Gura_2842 AAA family ATPase, CDC48 subfamily protein; ATPase AAA 2468521 8326420 Amir_2231 Actinosynnema mirum DSM 43827 ATPase AAA YP_003100017.1 2466722 D 446462 CDS YP_003100018.1 256376358 8326421 complement(2468559..2469467) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 2469467 8326421 Amir_2232 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100018.1 2468559 R 446462 CDS YP_003100019.1 256376359 8326422 complement(2469464..2470537) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 2470537 8326422 Amir_2233 Actinosynnema mirum DSM 43827 histidine kinase YP_003100019.1 2469464 R 446462 CDS YP_003100020.1 256376360 8326423 2470663..2471577 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cak:Caul_1642 ABC transporter; ABC transporter 2471577 8326423 Amir_2234 Actinosynnema mirum DSM 43827 ABC transporter YP_003100020.1 2470663 D 446462 CDS YP_003100021.1 256376361 8326424 2471574..2472341 1 NC_013093.1 KEGG: rpb:RPB_1462 binding-protein-dependent transport systems inner membrane component; hypothetical protein 2472341 8326424 Amir_2235 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100021.1 2471574 D 446462 CDS YP_003100022.1 256376362 8326425 2472380..2473294 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: ank:AnaeK_3196 aldo/keto reductase; aldo/keto reductase 2473294 8326425 Amir_2236 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003100022.1 2472380 D 446462 CDS YP_003100023.1 256376363 8326426 complement(2473356..2473865) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: pmr:PMI1779 NUDIX hydrolase; NUDIX hydrolase 2473865 8326426 Amir_2237 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003100023.1 2473356 R 446462 CDS YP_003100024.1 256376364 8326427 2474013..2476481 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: ade:Adeh_2042 hypothetical protein; hypothetical protein 2476481 8326427 Amir_2238 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100024.1 2474013 D 446462 CDS YP_003100025.1 256376365 8326428 2476536..2478035 1 NC_013093.1 PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; hypothetical protein 2478035 8326428 Amir_2239 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100025.1 2476536 D 446462 CDS YP_003100026.1 256376366 8326429 2478214..2478408 1 NC_013093.1 PFAM: protein of unknown function DUF797; hypothetical protein 2478408 8326429 Amir_2240 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100026.1 2478214 D 446462 CDS YP_003100027.1 256376367 8326430 2478472..2479320 1 NC_013093.1 PFAM: 20S proteasome A and B subunits; KEGG: GI10892 gene product from transcript GI10892- RA; 20S proteasome subunits A and B 2479320 8326430 Amir_2241 Actinosynnema mirum DSM 43827 20S proteasome subunits A and B YP_003100027.1 2478472 D 446462 CDS YP_003100028.1 256376368 8326431 2479365..2480156 1 NC_013093.1 PFAM: 20S proteasome A and B subunits; KEGG: proteasome subunit alpha type 2; K02726 20S proteasome subunit alpha 2; 20S proteasome subunits A and B 2480156 8326431 Amir_2242 Actinosynnema mirum DSM 43827 20S proteasome subunits A and B YP_003100028.1 2479365 D 446462 CDS YP_003100029.1 256376369 8326432 complement(2480214..2480768) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr4790 oxidoreductase; short-chain dehydrogenase/reductase SDR 2480768 8326432 Amir_2243 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100029.1 2480214 R 446462 CDS YP_003100030.1 256376370 8326433 2481067..2481660 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: azc:AZC_1061 transcriptional regulator; TetR family transcriptional regulator 2481660 8326433 Amir_2244 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100030.1 2481067 D 446462 CDS YP_003100031.1 256376371 8326434 complement(2482116..2484986) 1 NC_013093.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; ATPase AAA; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; LuxR family transcriptional regulator 2484986 8326434 Amir_2245 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100031.1 2482116 R 446462 CDS YP_003100032.1 256376372 8326435 complement(2485172..2486620) 1 NC_013093.1 PFAM: phosphoesterase PA-phosphatase related; diacylglycerol kinase catalytic region; SMART: phosphoesterase PA-phosphatase related; diacylglycerol kinase catalytic region; KEGG: scl:sce9292 hypothetical protein; PA-phosphatase-like phosphodiesterase 2486620 8326435 Amir_2246 Actinosynnema mirum DSM 43827 PA-phosphatase-like phosphodiesterase YP_003100032.1 2485172 R 446462 CDS YP_003100033.1 256376373 8326436 2486678..2488036 1 NC_013093.1 PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; hypothetical protein 2488036 8326436 Amir_2247 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100033.1 2486678 D 446462 CDS YP_003100034.1 256376374 8326437 2488163..2489047 1 NC_013093.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: afw:Anae109_0483 activator of HSP90 ATPase 1 family protein; Activator of Hsp90 ATPase 1 family protein 2489047 8326437 Amir_2248 Actinosynnema mirum DSM 43827 Activator of Hsp90 ATPase 1 family protein YP_003100034.1 2488163 D 446462 CDS YP_003100035.1 256376375 8326438 2489337..2490320 1 NC_013093.1 KEGG: mxa:MXAN_1359 hypothetical protein; transcriptional regulator protein 2490320 8326438 Amir_2249 Actinosynnema mirum DSM 43827 transcriptional regulator protein YP_003100035.1 2489337 D 446462 CDS YP_003100036.1 256376376 8326439 2490317..2491282 1 NC_013093.1 KEGG: mxa:MXAN_1360 hypothetical protein; transcriptional regulator protein 2491282 8326439 Amir_2250 Actinosynnema mirum DSM 43827 transcriptional regulator protein YP_003100036.1 2490317 D 446462 CDS YP_003100037.1 256376377 8326440 2491567..2491911 1 NC_013093.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: GG15783 gene product from transcript GG15783- RA; twin-arginine translocation protein, TatA/E family subunit 2491911 8326440 Amir_2251 Actinosynnema mirum DSM 43827 twin-arginine translocation protein, TatA/E family subunit YP_003100037.1 2491567 D 446462 CDS YP_003100038.1 256376378 8326441 2492065..2493153 1 NC_013093.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: nar:Saro_1096 sec-independent protein translocase TatC; Sec-independent protein translocase, TatC subunit 2493153 8326441 Amir_2252 Actinosynnema mirum DSM 43827 Sec-independent protein translocase, TatC subunit YP_003100038.1 2492065 D 446462 CDS YP_003100039.1 256376379 8326442 2493325..2494263 1 NC_013093.1 PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; KEGG: mxa:MXAN_6724 lipid kinase; diacylglycerol kinase catalytic subunit 2494263 8326442 Amir_2253 Actinosynnema mirum DSM 43827 diacylglycerol kinase catalytic subunit YP_003100039.1 2493325 D 446462 CDS YP_003100040.1 256376380 8326443 2494410..2497400 1 NC_013093.1 PFAM: DEAD/DEAH box helicase domain protein; DSH domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: predicted protein; DEAD/DEAH box helicase domain-containing protein 2497400 8326443 Amir_2254 Actinosynnema mirum DSM 43827 DEAD/DEAH box helicase domain-containing protein YP_003100040.1 2494410 D 446462 CDS YP_003100041.1 256376381 8326444 2497519..2498205 1 NC_013093.1 KEGG: scl:sce8934 hypothetical protein; hypothetical protein 2498205 8326444 Amir_2255 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100041.1 2497519 D 446462 CDS YP_003100042.1 256376382 8326445 2498480..2499784 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2499784 8326445 Amir_2256 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100042.1 2498480 D 446462 CDS YP_003100043.1 256376383 8326446 complement(2500259..2501308) 1 NC_013093.1 PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: rce:RC1_2483 DNA polymerase I; 5'-3' exonuclease 2501308 8326446 Amir_2257 Actinosynnema mirum DSM 43827 5'-3' exonuclease YP_003100043.1 2500259 R 446462 CDS YP_003100044.1 256376384 8326447 2501311..2502441 1 NC_013093.1 PFAM: peptidase M24; creatinase; KEGG: xca:xccb100_1756 proline dipeptidase; peptidase M24 2502441 8326447 Amir_2258 Actinosynnema mirum DSM 43827 peptidase M24 YP_003100044.1 2501311 D 446462 CDS YP_003100045.1 256376385 8326448 2502438..2502887 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: scl:sce5626 leucine responsive regulatory protein; AsnC family transcriptional regulator 2502887 8326448 Amir_2259 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003100045.1 2502438 D 446462 CDS YP_003100046.1 256376386 8326449 complement(2502933..2503679) 1 NC_013093.1 PFAM: aminotransferase class IV; KEGG: xac:XAC1291 hypothetical protein; class IV aminotransferase 2503679 8326449 Amir_2260 Actinosynnema mirum DSM 43827 class IV aminotransferase YP_003100046.1 2502933 R 446462 CDS YP_003100047.1 256376387 8326450 2503900..2505099 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_3713 transmembrane protein; major facilitator superfamily protein 2505099 8326450 Amir_2261 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100047.1 2503900 D 446462 CDS YP_003100048.1 256376388 8326451 2505398..2506690 1 NC_013093.1 KEGG: cvi:CV_1143 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 2506690 8326451 Amir_2262 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003100048.1 2505398 D 446462 CDS YP_003100049.1 256376389 8326452 2506855..2510202 1 NC_013093.1 KEGG: similar to CG6915-PA; hypothetical protein 2510202 8326452 Amir_2263 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100049.1 2506855 D 446462 CDS YP_003100050.1 256376390 8326453 complement(2510299..2511234) 1 NC_013093.1 PFAM: peptidase S58 DmpA; KEGG: xau:Xaut_4121 peptidase S58 DmpA; peptidase S58 DmpA 2511234 8326453 Amir_2264 Actinosynnema mirum DSM 43827 peptidase S58 DmpA YP_003100050.1 2510299 R 446462 CDS YP_003100051.1 256376391 8326454 2511342..2513468 1 NC_013093.1 KEGG: apl:APL_1681 hypothetical protein; hypothetical protein 2513468 8326454 Amir_2265 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100051.1 2511342 D 446462 CDS YP_003100052.1 256376392 8326455 complement(2513485..2515038) 1 NC_013093.1 PFAM: pyridoxal-dependent decarboxylase; KEGG: spe:Spro_3049 pyridoxal-dependent decarboxylase; pyridoxal-dependent decarboxylase 2515038 8326455 Amir_2266 Actinosynnema mirum DSM 43827 pyridoxal-dependent decarboxylase YP_003100052.1 2513485 R 446462 CDS YP_003100053.1 256376393 8326456 complement(2515213..2516898) 1 NC_013093.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: scl:sce0700 ATP-independent RNA helicase; DEAD/DEAH box helicase domain-containing protein 2516898 8326456 Amir_2267 Actinosynnema mirum DSM 43827 DEAD/DEAH box helicase domain-containing protein YP_003100053.1 2515213 R 446462 CDS YP_003100054.1 256376394 8326457 complement(2517111..2517725) 1 NC_013093.1 PFAM: RelA/SpoT domain protein; KEGG: bha:BH1885 hypothetical protein; RelA/SpoT domain-containing protein 2517725 8326457 Amir_2268 Actinosynnema mirum DSM 43827 RelA/SpoT domain-containing protein YP_003100054.1 2517111 R 446462 CDS YP_003100055.1 256376395 8326458 2517944..2518825 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: gbm:Gbem_3934 protein of unknown function DUF6 transmembrane; hypothetical protein 2518825 8326458 Amir_2269 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100055.1 2517944 D 446462 CDS YP_003100056.1 256376396 8326459 complement(2519123..2519617) 1 NC_013093.1 hypothetical protein 2519617 8326459 Amir_2270 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100056.1 2519123 R 446462 CDS YP_003100057.1 256376397 8326460 complement(2520093..2520635) 1 NC_013093.1 PFAM: YceI family protein; KEGG: afw:Anae109_3638 YceI family protein; YceI family protein 2520635 8326460 Amir_2271 Actinosynnema mirum DSM 43827 YceI family protein YP_003100057.1 2520093 R 446462 CDS YP_003100058.1 256376398 8326461 2520729..2521229 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rpa:RPA0821 MarR family transcriptional regulator; MarR family transcriptional regulator 2521229 8326461 Amir_2272 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100058.1 2520729 D 446462 CDS YP_003100059.1 256376399 8326462 2521578..2522549 1 NC_013093.1 PFAM: ATPase associated with various cellular activities AAA_3; magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; KEGG: gur:Gura_0187 ATPase; ATPase 2522549 8326462 Amir_2273 Actinosynnema mirum DSM 43827 ATPase YP_003100059.1 2521578 D 446462 CDS YP_003100060.1 256376400 8326463 2522546..2523670 1 NC_013093.1 PFAM: protein of unknown function DUF58; KEGG: scl:sce4442 hypothetical protein; hypothetical protein 2523670 8326463 Amir_2274 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100060.1 2522546 D 446462 CDS YP_003100061.1 256376401 8326464 2523842..2525509 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA1206 acetyl-coenzyme A synthetase; AMP-dependent synthetase and ligase 2525509 8326464 Amir_2275 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003100061.1 2523842 D 446462 CDS YP_003100062.1 256376402 8326465 complement(2525812..2526033) 1 NC_013093.1 hypothetical protein 2526033 8326465 Amir_2276 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100062.1 2525812 R 446462 CDS YP_003100063.1 256376403 8326466 2526257..2529535 1 NC_013093.1 KEGG: reu:Reut_A0253 methylmalonyl-CoA mutase, N- terminal:methylmalonyl-CoA mutase, C-terminal; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein; ArgK protein; methylmalonyl-CoA mutase, large subunit 2529535 8326466 Amir_2277 Actinosynnema mirum DSM 43827 methylmalonyl-CoA mutase, large subunit YP_003100063.1 2526257 D 446462 CDS YP_003100064.1 256376404 8326467 2529782..2530525 1 NC_013093.1 PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: bid:Bind_3201 hypothetical protein; hypothetical protein 2530525 8326467 Amir_2278 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100064.1 2529782 D 446462 CDS YP_003100065.1 256376405 8326468 complement(2530761..2533019) 1 NC_013093.1 KEGG: GH15499 gene product from transcript GH15499- RA; hypothetical protein 2533019 8326468 Amir_2279 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100065.1 2530761 R 446462 CDS YP_003100066.1 256376406 8326469 2533375..2535417 1 NC_013093.1 PFAM: DNA gyrase subunit B domain protein; TOPRIM domain protein; ATP-binding region ATPase domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; KEGG: bsu:BSU00060 DNA gyrase subunit B; DNA gyrase subunit B domain-containing protein 2535417 8326469 Amir_2280 Actinosynnema mirum DSM 43827 DNA gyrase subunit B domain-containing protein YP_003100066.1 2533375 D 446462 CDS YP_003100067.1 256376407 8326470 2535438..2538869 1 NC_013093.1 KEGG: bcz:BCZK0006 DNA gyrase subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; SMART: DNA gyrase/topoisomerase IV subunit A; Hedgehog/intein hint domain protein; DNA topoisomerase 2538869 8326470 Amir_2281 Actinosynnema mirum DSM 43827 DNA topoisomerase YP_003100067.1 2535438 D 446462 CDS YP_003100068.1 256376408 8326471 2539016..2539726 1 NC_013093.1 PFAM: xylose isomerase; KEGG: atc:AGR_L_3397 hypothetical protein; xylose isomerase 2539726 8326471 Amir_2282 Actinosynnema mirum DSM 43827 xylose isomerase YP_003100068.1 2539016 D 446462 CDS YP_003100069.1 256376409 8326472 2539803..2540360 1 NC_013093.1 KEGG: scl:sce8945 hypothetical protein; hypothetical protein 2540360 8326472 Amir_2283 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100069.1 2539803 D 446462 CDS YP_003100070.1 256376410 8326473 2540484..2541632 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: pfo:Pfl01_0703 luciferase-like; luciferase-like monooxygenase 2541632 8326473 Amir_2284 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100070.1 2540484 D 446462 CDS YP_003100071.1 256376411 8326474 2541629..2542222 1 NC_013093.1 PFAM: NADPH-dependent FMN reductase; KEGG: rsq:Rsph17025_0771 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 2542222 8326474 Amir_2285 Actinosynnema mirum DSM 43827 NADPH-dependent FMN reductase YP_003100071.1 2541629 D 446462 CDS YP_003100072.1 256376412 8326475 2542609..2543472 1 NC_013093.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2543472 hisG 8326475 hisG Actinosynnema mirum DSM 43827 ATP phosphoribosyltransferase YP_003100072.1 2542609 D 446462 CDS YP_003100073.1 256376413 8326476 complement(2543824..2546346) 1 NC_013093.1 KEGG: msl:Msil_2593 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; EAL domain protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 2546346 8326476 Amir_2287 Actinosynnema mirum DSM 43827 PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase YP_003100073.1 2543824 R 446462 CDS YP_003100074.1 256376414 8326477 2546957..2547448 1 NC_013093.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: pol:Bpro_1654 hypothetical protein; Activator of Hsp90 ATPase 1 family protein 2547448 8326477 Amir_2288 Actinosynnema mirum DSM 43827 Activator of Hsp90 ATPase 1 family protein YP_003100074.1 2546957 D 446462 CDS YP_003100075.1 256376415 8326478 complement(2547608..2548195) 1 NC_013093.1 hypothetical protein 2548195 8326478 Amir_2289 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100075.1 2547608 R 446462 CDS YP_003100076.1 256376416 8326479 complement(2548308..2549093) 1 NC_013093.1 KEGG: bcy:Bcer98_2113 hypothetical protein; hypothetical protein 2549093 8326479 Amir_2290 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100076.1 2548308 R 446462 CDS YP_003100077.1 256376417 8326480 complement(2549090..2550697) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcy:Bcer98_2114 ABC transporter-related protein; ABC transporter 2550697 8326480 Amir_2291 Actinosynnema mirum DSM 43827 ABC transporter YP_003100077.1 2549090 R 446462 CDS YP_003100078.1 256376418 8326481 complement(2550694..2551767) 1 NC_013093.1 PFAM: cobalt transport protein; KEGG: hha:Hhal_0811 NADH/ubiquinone/plastoquinone (complex I); cobalt transport protein 2551767 8326481 Amir_2292 Actinosynnema mirum DSM 43827 cobalt transport protein YP_003100078.1 2550694 R 446462 CDS YP_003100079.1 256376419 8326482 complement(2551764..2551892) 1 NC_013093.1 hypothetical protein 2551892 8326482 Amir_2293 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100079.1 2551764 R 446462 CDS YP_003100080.1 256376420 8326483 complement(2551889..2552758) 1 NC_013093.1 KEGG: MTA2; hydroxyproline-rich glycoprotein; hypothetical protein 2552758 8326483 Amir_2294 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100080.1 2551889 R 446462 CDS YP_003100081.1 256376421 8326484 complement(2552755..2554044) 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: hypothetical protein; LPXTG-motif cell wall anchor domain-containing protein 2554044 8326484 Amir_2295 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003100081.1 2552755 R 446462 CDS YP_003100082.1 256376422 8326485 complement(2554364..2554993) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: bur:Bcep18194_A5869 hypothetical protein; type 11 methyltransferase 2554993 8326485 Amir_2296 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003100082.1 2554364 R 446462 CDS YP_003100083.1 256376423 8326486 complement(2555032..2555436) 1 NC_013093.1 hypothetical protein 2555436 8326486 Amir_2297 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100083.1 2555032 R 446462 CDS YP_003100084.1 256376424 8326487 2555558..2556727 1 NC_013093.1 PFAM: ROK family protein; KEGG: vei:Veis_3275 ROK family protein; ROK family protein 2556727 8326487 Amir_2298 Actinosynnema mirum DSM 43827 ROK family protein YP_003100084.1 2555558 D 446462 CDS YP_003100085.1 256376425 8326488 2557317..2558453 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: bha:BH0710 hypothetical protein; oxidoreductase domain-containing protein 2558453 8326488 Amir_2299 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003100085.1 2557317 D 446462 CDS YP_003100086.1 256376426 8326489 2558507..2559511 1 NC_013093.1 PFAM: xylose isomerase; AP endonuclease 2 domain protein; KEGG: vei:Veis_3268 xylose isomerase domain protein TIM barrel; xylose isomerase 2559511 8326489 Amir_2300 Actinosynnema mirum DSM 43827 xylose isomerase YP_003100086.1 2558507 D 446462 CDS YP_003100087.1 256376427 8326490 2559650..2560891 1 NC_013093.1 PFAM: FAD linked oxidase domain protein; D- arabinono-14-lactone oxidase; KEGG: hypothetical protein; FAD linked oxidase domain-containing protein 2560891 8326490 Amir_2301 Actinosynnema mirum DSM 43827 FAD linked oxidase domain-containing protein YP_003100087.1 2559650 D 446462 CDS YP_003100088.1 256376428 8326491 2561488..2562660 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: swi:Swit_4414 protein of unknown function DUF894, DitE; major facilitator superfamily protein 2562660 8326491 Amir_2302 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100088.1 2561488 D 446462 CDS YP_003100089.1 256376429 8326492 2562725..2562820 1 NC_013093.1 hypothetical protein 2562820 8326492 Amir_2303 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100089.1 2562725 D 446462 CDS YP_003100090.1 256376430 8326493 2562817..2563404 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rlt:Rleg2_0103 transcriptional regulator, TetR family; TetR family transcriptional regulator 2563404 8326493 Amir_2304 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100090.1 2562817 D 446462 CDS YP_003100091.1 256376431 8326494 complement(2563426..2563617) 1 NC_013093.1 hypothetical protein 2563617 8326494 Amir_2305 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100091.1 2563426 R 446462 CDS YP_003100092.1 256376432 8326495 2563846..2564202 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rpe:RPE_3910 anti-sigma-factor antagonist; anti-sigma-factor antagonist 2564202 8326495 Amir_2306 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003100092.1 2563846 D 446462 CDS YP_003100093.1 256376433 8326496 2564267..2564923 1 NC_013093.1 TIGRFAM: methylase; PFAM: methyltransferase small; KEGG: acp:A2cp1_0395 modification methylase, HemK family; methylase 2564923 8326496 Amir_2307 Actinosynnema mirum DSM 43827 methylase YP_003100093.1 2564267 D 446462 CDS YP_003100094.1 256376434 8326497 2564958..2565125 1 NC_013093.1 SMART: hypothetical protein; hypothetical protein 2565125 8326497 Amir_2308 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100094.1 2564958 D 446462 CDS YP_003100095.1 256376435 8326498 complement(2565264..2566280) 1 NC_013093.1 KEGG: pzu:PHZ_c0782 hypothetical protein; hypothetical protein 2566280 8326498 Amir_2309 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100095.1 2565264 R 446462 CDS YP_003100096.1 256376436 8326499 complement(2566506..2567657) 1 NC_013093.1 PFAM: glutamate--cysteine ligase GCS2; KEGG: dsh:Dshi_1749 carboxylate-amine ligase; glutamate--cysteine ligase GCS2 2567657 8326499 Amir_2310 Actinosynnema mirum DSM 43827 glutamate--cysteine ligase GCS2 YP_003100096.1 2566506 R 446462 CDS YP_003100097.1 256376437 8326500 complement(2567744..2568781) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: bbt:BBta_7516 alkanal monooxygenase; luciferase-like monooxygenase 2568781 8326500 Amir_2311 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100097.1 2567744 R 446462 CDS YP_003100098.1 256376438 8326501 complement(2568801..2570450) 1 NC_013093.1 KEGG: mxa:MXAN_2785 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS/PAC sensor signal transduction histidine kinase 2570450 8326501 Amir_2312 Actinosynnema mirum DSM 43827 PAS/PAC sensor signal transduction histidine kinase YP_003100098.1 2568801 R 446462 CDS YP_003100099.1 256376439 8326502 complement(2570477..2570764) 1 NC_013093.1 hypothetical protein 2570764 8326502 Amir_2313 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100099.1 2570477 R 446462 CDS YP_003100100.1 256376440 8326503 complement(2570769..2573942) 1 NC_013093.1 KEGG: SNF2 superfamily protein; hypothetical protein 2573942 8326503 Amir_2314 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100100.1 2570769 R 446462 CDS YP_003100101.1 256376441 8326504 complement(2573920..2575962) 1 NC_013093.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: bha:BH2438 flagellar biosynthesis protein FlhA; flagellar biosynthesis protein FlhA 2575962 8326504 Amir_2315 Actinosynnema mirum DSM 43827 flagellar biosynthesis protein FlhA YP_003100101.1 2573920 R 446462 CDS YP_003100102.1 256376442 8326505 complement(2576069..2576545) 1 NC_013093.1 hypothetical protein 2576545 8326505 Amir_2316 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100102.1 2576069 R 446462 CDS YP_003100103.1 256376443 8326506 complement(2576551..2576913) 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dds:Ddes_0324 response regulator receiver protein; response regulator receiver protein 2576913 8326506 Amir_2317 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003100103.1 2576551 R 446462 CDS YP_003100104.1 256376444 8326507 complement(2576910..2577395) 1 NC_013093.1 KEGG: aba:Acid345_1530 hypothetical protein; hypothetical protein 2577395 8326507 Amir_2318 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100104.1 2576910 R 446462 CDS YP_003100105.1 256376445 8326508 complement(2577392..2577781) 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: aba:Acid345_1527 response regulator receiver protein, CheY; response regulator receiver protein 2577781 8326508 Amir_2319 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003100105.1 2577392 R 446462 CDS YP_003100106.1 256376446 8326509 complement(2577766..2578641) 1 NC_013093.1 KEGG: aba:Acid345_1529 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; methyltransferase type 12; SMART: MCP methyltransferase CheR-type; CheR-type MCP methyltransferase 2578641 8326509 Amir_2320 Actinosynnema mirum DSM 43827 CheR-type MCP methyltransferase YP_003100106.1 2577766 R 446462 CDS YP_003100107.1 256376447 8326510 complement(2578641..2579825) 1 NC_013093.1 KEGG: mmr:Mmar10_0661 chemotaxis-specific methylesterase; PFAM: CheB methylesterase; response regulator receiver; SMART: response regulator receiver; response regulator receiver modulated CheB methylesterase 2579825 8326510 Amir_2321 Actinosynnema mirum DSM 43827 response regulator receiver modulated CheB methylesterase YP_003100107.1 2578641 R 446462 CDS YP_003100108.1 256376448 8326511 complement(2580177..2581037) 1 NC_013093.1 hypothetical protein 2581037 8326511 Amir_2322 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100108.1 2580177 R 446462 CDS YP_003100109.1 256376449 8326512 complement(2581156..2582793) 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1526 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 2582793 8326512 Amir_2323 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003100109.1 2581156 R 446462 CDS YP_003100110.1 256376450 8326513 complement(2582970..2583404) 1 NC_013093.1 PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: aba:Acid345_1525 CheW protein; CheW protein 2583404 8326513 Amir_2324 Actinosynnema mirum DSM 43827 CheW protein YP_003100110.1 2582970 R 446462 CDS YP_003100111.1 256376451 8326514 complement(2583407..2585689) 1 NC_013093.1 PFAM: CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; ATP- binding region ATPase domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: aba:Acid345_1524 CheA signal transduction histidine kinases; CheA signal transduction histidine kinase 2585689 8326514 Amir_2325 Actinosynnema mirum DSM 43827 CheA signal transduction histidine kinase YP_003100111.1 2583407 R 446462 CDS YP_003100112.1 256376452 8326515 complement(2586401..2586616) 1 NC_013093.1 hypothetical protein 2586616 8326515 Amir_2326 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100112.1 2586401 R 446462 CDS YP_003100113.1 256376453 8326516 2586841..2587329 1 NC_013093.1 KEGG: bxe:Bxe_B0776 membrane glycoprotein; hypothetical protein 2587329 8326516 Amir_2327 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100113.1 2586841 D 446462 CDS YP_003100114.1 256376454 8326517 complement(2587723..2588814) 1 NC_013093.1 PFAM: type III secretion exporter; KEGG: cti:RALTA_B0268 FlhB: flagellar biosynthetic protein. FlhB/HrpN/YscU/SpaS family.; type III secretion exporter 2588814 8326517 Amir_2328 Actinosynnema mirum DSM 43827 type III secretion exporter YP_003100114.1 2587723 R 446462 CDS YP_003100115.1 256376455 8326518 complement(2588822..2589592) 1 NC_013093.1 PFAM: type III secretion system inner membrane R protein; KEGG: tbd:Tbd_1612 flagellar biosynthesis protein FliR; type III secretion system inner membrane R protein 2589592 8326518 Amir_2329 Actinosynnema mirum DSM 43827 type III secretion system inner membrane R protein YP_003100115.1 2588822 R 446462 CDS YP_003100116.1 256376456 8326519 complement(2589601..2589873) 1 NC_013093.1 PFAM: export protein FliQ family 3; KEGG: tgr:Tgr7_1332 flagellar biosynthetic protein FliQ; export protein FliQ family 3 2589873 8326519 Amir_2330 Actinosynnema mirum DSM 43827 export protein FliQ family 3 YP_003100116.1 2589601 R 446462 CDS YP_003100117.1 256376457 8326520 complement(2589885..2590766) 1 NC_013093.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2590766 fliP 8326520 fliP Actinosynnema mirum DSM 43827 flagellar biosynthesis protein FliP YP_003100117.1 2589885 R 446462 CDS YP_003100118.1 256376458 8326521 complement(2590763..2591719) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2591719 8326521 Amir_2332 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100118.1 2590763 R 446462 CDS YP_003100119.1 256376459 8326522 complement(2591719..2592471) 1 NC_013093.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: bvi:Bcep1808_0049 flagellar motor switch protein FliN; flagellar motor switch protein FliN 2592471 8326522 Amir_2333 Actinosynnema mirum DSM 43827 flagellar motor switch protein FliN YP_003100119.1 2591719 R 446462 CDS YP_003100120.1 256376460 8326523 complement(2592468..2593430) 1 NC_013093.1 PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; KEGG: hhe:HH1147 flagellar motor switch protein FliM; flagellar motor switch protein FliM 2593430 8326523 Amir_2334 Actinosynnema mirum DSM 43827 flagellar motor switch protein FliM YP_003100120.1 2592468 R 446462 CDS YP_003100121.1 256376461 8326524 complement(2593641..2594090) 1 NC_013093.1 PFAM: flagellar basal body-associated protein FliL; KEGG: rso:RSp0379 flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL 2594090 8326524 Amir_2335 Actinosynnema mirum DSM 43827 flagellar basal body-associated protein FliL YP_003100121.1 2593641 R 446462 CDS YP_003100122.1 256376462 8326525 complement(2594116..2595003) 1 NC_013093.1 PFAM: OmpA/MotB domain protein; KEGG: ppd:Ppro_3470 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein 2595003 8326525 Amir_2336 Actinosynnema mirum DSM 43827 OmpA/MotB domain-containing protein YP_003100122.1 2594116 R 446462 CDS YP_003100123.1 256376463 8326526 complement(2595003..2595776) 1 NC_013093.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: glo:Glov_0031 MotA/TolQ/ExbB proton channel; MotA/TolQ/ExbB proton channel 2595776 8326526 Amir_2337 Actinosynnema mirum DSM 43827 MotA/TolQ/ExbB proton channel YP_003100123.1 2595003 R 446462 CDS YP_003100124.1 256376464 8326527 complement(2595777..2596082) 1 NC_013093.1 PFAM: flagellar FlbD family protein; KEGG: bha:BH2448 hypothetical protein; flagellar FlbD family protein 2596082 8326527 Amir_2338 Actinosynnema mirum DSM 43827 flagellar FlbD family protein YP_003100124.1 2595777 R 446462 CDS YP_003100125.1 256376465 8326528 complement(2596215..2597045) 1 NC_013093.1 PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: bha:BH2449 flagellar basal body rod protein FlgG; hypothetical protein 2597045 8326528 Amir_2339 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100125.1 2596215 R 446462 CDS YP_003100126.1 256376466 8326529 complement(2597106..2597525) 1 NC_013093.1 PFAM: flagellar hook capping protein; KEGG: rpe:RPE_1177 flagellar basal body rod modification protein; flagellar hook capping protein 2597525 8326529 Amir_2340 Actinosynnema mirum DSM 43827 flagellar hook capping protein YP_003100126.1 2597106 R 446462 CDS YP_003100127.1 256376467 8326530 complement(2597554..2599590) 1 NC_013093.1 PFAM: flagellar hook-length control protein; KEGG: SNF2 superfamily protein; flagellar hook-length control protein 2599590 8326530 Amir_2341 Actinosynnema mirum DSM 43827 flagellar hook-length control protein YP_003100127.1 2597554 R 446462 CDS YP_003100128.1 256376468 8326531 complement(2599591..2600574) 1 NC_013093.1 PFAM: lytic transglycosylase catalytic; NLP/P60 protein; KEGG: bsu:BSU11570 hypothetical protein; lytic transglycosylase 2600574 8326531 Amir_2342 Actinosynnema mirum DSM 43827 lytic transglycosylase YP_003100128.1 2599591 R 446462 CDS YP_003100129.1 256376469 8326532 complement(2600571..2600999) 1 NC_013093.1 KEGG: bra:BRADO2721 TolA family protein; TolA family protein 2600999 8326532 Amir_2343 Actinosynnema mirum DSM 43827 TolA family protein YP_003100129.1 2600571 R 446462 CDS YP_003100130.1 256376470 8326533 complement(2600996..2602315) 1 NC_013093.1 KEGG: afw:Anae109_2216 FliI/YscN family ATPase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: ATPase AAA; FliI/YscN family ATPase 2602315 8326533 Amir_2344 Actinosynnema mirum DSM 43827 FliI/YscN family ATPase YP_003100130.1 2600996 R 446462 CDS YP_003100131.1 256376471 8326534 complement(2602312..2602992) 1 NC_013093.1 PFAM: flagellar assembly protein FliH; KEGG: azo:azo2718 flagellar assembly protein FliH; flagellar assembly protein FliH 2602992 8326534 Amir_2345 Actinosynnema mirum DSM 43827 flagellar assembly protein FliH YP_003100131.1 2602312 R 446462 CDS YP_003100132.1 256376472 8326535 complement(2602973..2603989) 1 NC_013093.1 TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; KEGG: bha:BH2457 flagellar motor switch protein G; flagellar motor switch protein FliG 2603989 8326535 Amir_2346 Actinosynnema mirum DSM 43827 flagellar motor switch protein FliG YP_003100132.1 2602973 R 446462 CDS YP_003100133.1 256376473 8326536 complement(2603991..2605670) 1 NC_013093.1 TIGRFAM: flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring domain protein; KEGG: gbm:Gbem_3838 flagellar M-ring protein FliF; flagellar M-ring protein FliF 2605670 8326536 Amir_2347 Actinosynnema mirum DSM 43827 flagellar M-ring protein FliF YP_003100133.1 2603991 R 446462 CDS YP_003100134.1 256376474 8326537 complement(2605667..2605984) 1 NC_013093.1 PFAM: flagellar hook-basal body complex protein FliE; KEGG: pca:Pcar_1193 flagellar hook-basal body complex protein FliE; flagellar hook-basal body complex protein FliE 2605984 8326537 Amir_2348 Actinosynnema mirum DSM 43827 flagellar hook-basal body complex protein FliE YP_003100134.1 2605667 R 446462 CDS YP_003100135.1 256376475 8326538 complement(2605981..2606379) 1 NC_013093.1 PFAM: protein of unknown function DUF1078 domain protein; KEGG: efe:EFER_1855 flagellar component of cell- proximal portion of basal-body rod; hypothetical protein 2606379 8326538 Amir_2349 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100135.1 2605981 R 446462 CDS YP_003100136.1 256376476 8326539 complement(2606381..2606737) 1 NC_013093.1 TIGRFAM: flagellar basal-body rod protein FlgB; KEGG: eta:ETA_20410 flagellar basal-body rod protein; flagellar basal-body rod protein FlgB 2606737 8326539 Amir_2350 Actinosynnema mirum DSM 43827 flagellar basal-body rod protein FlgB YP_003100136.1 2606381 R 446462 CDS YP_003100137.1 256376477 8326540 complement(2607284..2607619) 1 NC_013093.1 hypothetical protein 2607619 8326540 Amir_2351 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100137.1 2607284 R 446462 CDS YP_003100138.1 256376478 8326541 complement(2607616..2608014) 1 NC_013093.1 TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS; KEGG: pca:Pcar_1111 flagellar protein FliS; flagellar protein FliS 2608014 8326541 Amir_2352 Actinosynnema mirum DSM 43827 flagellar protein FliS YP_003100138.1 2607616 R 446462 CDS YP_003100139.1 256376479 8326542 complement(2608022..2609314) 1 NC_013093.1 PFAM: flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; flagellar hook- associated protein 2 domain protein; KEGG: xcb:XC_2246 flagellar protein; flagellar hook-associated 2 domain-containing protein 2609314 8326542 Amir_2353 Actinosynnema mirum DSM 43827 flagellar hook-associated 2 domain-containing protein YP_003100139.1 2608022 R 446462 CDS YP_003100140.1 256376480 8326543 complement(2609457..2610617) 1 NC_013093.1 PFAM: flagellin domain protein; KEGG: nmu:Nmul_A1337 flagellin-like; flagellin domain-containing protein 2610617 8326543 Amir_2354 Actinosynnema mirum DSM 43827 flagellin domain-containing protein YP_003100140.1 2609457 R 446462 CDS YP_003100141.1 256376481 8326544 complement(2611185..2612069) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 3 domain protein; KEGG: gbm:Gbem_3764 RNA polymerase, sigma 28 subunit, FliA/WhiG; FliA/WhiG subfamily RNA polymerase sigma-28 subunit 2612069 8326544 Amir_2355 Actinosynnema mirum DSM 43827 FliA/WhiG subfamily RNA polymerase sigma-28 subunit YP_003100141.1 2611185 R 446462 CDS YP_003100142.1 256376482 8326545 2612305..2612787 1 NC_013093.1 PFAM: FlgN family protein; KEGG: gur:Gura_4100 hypothetical protein; FlgN family protein 2612787 8326545 Amir_2356 Actinosynnema mirum DSM 43827 FlgN family protein YP_003100142.1 2612305 D 446462 CDS YP_003100143.1 256376483 8326546 2612790..2614169 1 NC_013093.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: ppd:Ppro_3455 flagellar hook-associated protein FlgK; flagellar hook-associated protein FlgK 2614169 8326546 Amir_2357 Actinosynnema mirum DSM 43827 flagellar hook-associated protein FlgK YP_003100143.1 2612790 D 446462 CDS YP_003100144.1 256376484 8326547 2614176..2615054 1 NC_013093.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: gur:Gura_4098 flagellar hook-associated protein 3; flagellar hook-associated protein 3 2615054 8326547 Amir_2358 Actinosynnema mirum DSM 43827 flagellar hook-associated protein 3 YP_003100144.1 2614176 D 446462 CDS YP_003100145.1 256376485 8326548 2615051..2615563 1 NC_013093.1 PFAM: protein of unknown function DUF180; KEGG: dps:DP2692 flagellar assembly protein FliW; hypothetical protein 2615563 8326548 Amir_2359 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100145.1 2615051 D 446462 CDS YP_003100146.1 256376486 8326549 2615517..2615777 1 NC_013093.1 TIGRFAM: carbon storage regulator; PFAM: carbon storage regulator; KEGG: mca:MCA0391 carbon storage regulator; carbon storage regulator, CsrA 2615777 8326549 Amir_2360 Actinosynnema mirum DSM 43827 carbon storage regulator, CsrA YP_003100146.1 2615517 D 446462 CDS YP_003100147.1 256376487 8326550 2616167..2617858 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proprotein convertase P; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 2617858 8326550 Amir_2361 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003100147.1 2616167 D 446462 CDS YP_003100148.1 256376488 8326551 2617931..2619571 1 NC_013093.1 KEGG: sus:Acid_3859 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAS/PAC sensor hybrid histidine kinase 2619571 8326551 Amir_2362 Actinosynnema mirum DSM 43827 PAS/PAC sensor hybrid histidine kinase YP_003100148.1 2617931 D 446462 CDS YP_003100149.1 256376489 8326552 2619568..2619948 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: rce:RC1_0432 KDP operon transcriptional regulatory protein KdpE; response regulator receiver protein 2619948 8326552 Amir_2363 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003100149.1 2619568 D 446462 CDS YP_003100150.1 256376490 8326553 complement(2620431..2621354) 1 NC_013093.1 PFAM: NmrA family protein; KEGG: sus:Acid_6298 NmrA family protein; NmrA family protein 2621354 8326553 Amir_2364 Actinosynnema mirum DSM 43827 NmrA family protein YP_003100150.1 2620431 R 446462 CDS YP_003100151.1 256376491 8326554 complement(2621432..2621875) 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: mxa:MXAN_6486 transcriptional regulator, MarR family; MarR family transcriptional regulator 2621875 8326554 Amir_2365 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100151.1 2621432 R 446462 CDS YP_003100152.1 256376492 8326555 complement(2622036..2624204) 1 NC_013093.1 KEGG: bmj:BMULJ_06047 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase A domain protein; ATP- binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: histidine kinase A domain protein; PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase 2624204 8326555 Amir_2366 Actinosynnema mirum DSM 43827 PAS/PAC sensor signal transduction histidine kinase YP_003100152.1 2622036 R 446462 CDS YP_003100153.1 256376493 8326556 2624616..2626895 1 NC_013093.1 KEGG: mag:amb2954 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase 2626895 8326556 Amir_2367 Actinosynnema mirum DSM 43827 PAS/PAC sensor signal transduction histidine kinase YP_003100153.1 2624616 D 446462 CDS YP_003100154.1 256376494 8326557 2626892..2628103 1 NC_013093.1 PFAM: Metal-dependent hydrolase HDOD; response regulator receiver; SMART: response regulator receiver; KEGG: dvu:DVU0330 response regulator; signal transduction protein 2628103 8326557 Amir_2368 Actinosynnema mirum DSM 43827 signal transduction protein YP_003100154.1 2626892 D 446462 CDS YP_003100155.1 256376495 8326558 complement(2628258..2628422) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2628422 8326558 Amir_2369 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100155.1 2628258 R 446462 CDS YP_003100156.1 256376496 8326559 2628647..2632948 1 NC_013093.1 KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein; multi-sensor hybrid histidine kinase 2632948 8326559 Amir_2370 Actinosynnema mirum DSM 43827 multi-sensor hybrid histidine kinase YP_003100156.1 2628647 D 446462 CDS YP_003100157.1 256376497 8326560 2633170..2634318 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: sat:SYN_01373 hydrogenase transcriptional regulatory protein; response regulator receiver protein 2634318 8326560 Amir_2371 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003100157.1 2633170 D 446462 CDS YP_003100158.1 256376498 8326561 complement(2634367..2635044) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pol:Bpro_0417 transcriptional regulator, GntR family; GntR family transcriptional regulator 2635044 8326561 Amir_2372 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003100158.1 2634367 R 446462 CDS YP_003100159.1 256376499 8326562 2635467..2636114 1 NC_013093.1 hypothetical protein 2636114 8326562 Amir_2373 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100159.1 2635467 D 446462 CDS YP_003100160.1 256376500 8326563 2636206..2636730 1 NC_013093.1 PFAM: CHRD domain containing protein; SMART: CHRD domain containing protein; KEGG: pzu:PHZ_c0812 hypothetical protein; CHRD domain containing protein 2636730 8326563 Amir_2374 Actinosynnema mirum DSM 43827 CHRD domain containing protein YP_003100160.1 2636206 D 446462 CDS YP_003100161.1 256376501 8326564 complement(2636829..2637188) 1 NC_013093.1 KEGG: bja:blr0122 hypothetical protein; hypothetical protein 2637188 8326564 Amir_2375 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100161.1 2636829 R 446462 CDS YP_003100162.1 256376502 8326565 2637274..2637786 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: efe:EFER_2801 MarR-family regulatory protein; MarR family transcriptional regulator 2637786 8326565 Amir_2376 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100162.1 2637274 D 446462 CDS YP_003100163.1 256376503 8326566 complement(2637971..2638822) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; XRE family transcriptional regulator 2638822 8326566 Amir_2377 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100163.1 2637971 R 446462 CDS YP_003100164.1 256376504 8326567 2638942..2639841 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: hypothetical protein; short-chain dehydrogenase/reductase SDR 2639841 8326567 Amir_2378 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100164.1 2638942 D 446462 CDS YP_003100165.1 256376505 8326568 2639910..2640227 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2640227 8326568 Amir_2379 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100165.1 2639910 D 446462 CDS YP_003100166.1 256376506 8326569 2640465..2642477 1 NC_013093.1 KEGG: pen:PSEEN0086 alginate biosynthesis sensor protein KinB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; MASE1 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS/PAC sensor signal transduction histidine kinase 2642477 8326569 Amir_2380 Actinosynnema mirum DSM 43827 PAS/PAC sensor signal transduction histidine kinase YP_003100166.1 2640465 D 446462 CDS YP_003100167.1 256376507 8326570 complement(2642971..2643297) 1 NC_013093.1 PFAM: branched-chain amino acid transport; KEGG: pin:Ping_3723 branched-chain amino acid transport; branched-chain amino acid transport 2643297 8326570 Amir_2381 Actinosynnema mirum DSM 43827 branched-chain amino acid transport YP_003100167.1 2642971 R 446462 CDS YP_003100168.1 256376508 8326571 complement(2643290..2643949) 1 NC_013093.1 PFAM: AzlC family protein; KEGG: sbl:Sbal_4248 AzlC family protein; AzlC family protein 2643949 8326571 Amir_2382 Actinosynnema mirum DSM 43827 AzlC family protein YP_003100168.1 2643290 R 446462 CDS YP_003100169.1 256376509 8326572 2644102..2644560 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: spe:Spro_3514 AsnC family transcriptional regulator; AsnC family transcriptional regulator 2644560 8326572 Amir_2383 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003100169.1 2644102 D 446462 CDS YP_003100170.1 256376510 8326573 complement(2644572..2645897) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr5567 hypothetical protein; major facilitator superfamily protein 2645897 8326573 Amir_2384 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100170.1 2644572 R 446462 CDS YP_003100171.1 256376511 8326574 2646047..2646577 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mlo:mlr3465 TetR family transcriptional regulator; TetR family transcriptional regulator 2646577 8326574 Amir_2385 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100171.1 2646047 D 446462 CDS YP_003100172.1 256376512 8326575 complement(2646701..2647252) 1 NC_013093.1 hypothetical protein 2647252 8326575 Amir_2386 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100172.1 2646701 R 446462 CDS YP_003100173.1 256376513 8326576 complement(2647423..2647839) 1 NC_013093.1 PFAM: RbsD or FucU transport; KEGG: csa:Csal_0367 RbsD or FucU transport; RbsD or FucU transport 2647839 8326576 Amir_2387 Actinosynnema mirum DSM 43827 RbsD or FucU transport YP_003100173.1 2647423 R 446462 CDS YP_003100174.1 256376514 8326577 2648184..2648804 1 NC_013093.1 KEGG: predicted gene, 672682; hypothetical protein 2648804 8326577 Amir_2388 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100174.1 2648184 D 446462 CDS YP_003100175.1 256376515 8326578 complement(2648876..2649811) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: bac:BamMC406_3547 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 2649811 8326578 Amir_2389 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003100175.1 2648876 R 446462 CDS YP_003100176.1 256376516 8326579 2649898..2650608 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bpy:Bphyt_6333 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 2650608 8326579 Amir_2390 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100176.1 2649898 D 446462 CDS YP_003100177.1 256376517 8326580 complement(2650679..2651008) 1 NC_013093.1 hypothetical protein 2651008 8326580 Amir_2391 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100177.1 2650679 R 446462 CDS YP_003100178.1 256376518 8326581 complement(2651158..2653098) 1 NC_013093.1 molecular chaperone; heat shock protein 90 2653098 8326581 Amir_2392 Actinosynnema mirum DSM 43827 heat shock protein 90 YP_003100178.1 2651158 R 446462 CDS YP_003100179.1 256376519 8326582 2653747..2654220 1 NC_013093.1 KEGG: rpi:Rpic_3955 transcriptional regulator, MarR family; hypothetical protein 2654220 8326582 Amir_2393 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100179.1 2653747 D 446462 CDS YP_003100180.1 256376520 8326583 complement(2654409..2655014) 1 NC_013093.1 hypothetical protein 2655014 8326583 Amir_2394 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100180.1 2654409 R 446462 CDS YP_003100181.1 256376521 8326584 2655266..2656051 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: pde:Pden_1769 3-oxoacyl-(acyl-carrier- protein) reductase; short-chain dehydrogenase/reductase SDR 2656051 8326584 Amir_2395 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100181.1 2655266 D 446462 CDS YP_003100182.1 256376522 8326585 complement(2656107..2656499) 1 NC_013093.1 hypothetical protein 2656499 8326585 Amir_2396 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100182.1 2656107 R 446462 CDS YP_003100183.1 256376523 8326586 complement(2657193..2658218) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: oxidoreductase protein; luciferase-like monooxygenase 2658218 8326586 Amir_2397 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100183.1 2657193 R 446462 CDS YP_003100184.1 256376524 8326587 complement(2658282..2658647) 1 NC_013093.1 PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: tcx:Tcr_0016 RNA-binding S4; RNA-binding S4 domain-containing protein 2658647 8326587 Amir_2398 Actinosynnema mirum DSM 43827 RNA-binding S4 domain-containing protein YP_003100184.1 2658282 R 446462 CDS YP_003100185.1 256376525 8326588 2658806..2659078 1 NC_013093.1 KEGG: gbm:Gbem_1481 transglycosylase-associated protein; hypothetical protein 2659078 8326588 Amir_2399 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100185.1 2658806 D 446462 CDS YP_003100186.1 256376526 8326589 2659363..2660220 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: swi:Swit_2098 luciferase family protein; luciferase-like monooxygenase 2660220 8326589 Amir_2400 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100186.1 2659363 D 446462 CDS YP_003100187.1 256376527 8326590 2660361..2661191 1 NC_013093.1 PFAM: siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: smt:Smal_2998 FAD-binding 9 siderophore- interacting domain protein; siderophore-interacting protein 2661191 8326590 Amir_2401 Actinosynnema mirum DSM 43827 siderophore-interacting protein YP_003100187.1 2660361 D 446462 CDS YP_003100188.1 256376528 8326591 2661365..2661991 1 NC_013093.1 KEGG: pde:Pden_0727 MotA/TolQ/ExbB proton channel; hypothetical protein 2661991 8326591 Amir_2402 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100188.1 2661365 D 446462 CDS YP_003100189.1 256376529 8326592 complement(2661981..2663120) 1 NC_013093.1 KEGG: aha:AHA_2314 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2663120 8326592 Amir_2403 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003100189.1 2661981 R 446462 CDS YP_003100190.1 256376530 8326593 2663250..2664524 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: mmw:Mmwyl1_2762 extracellular solute-binding protein; family 1 extracellular solute-binding protein 2664524 8326593 Amir_2404 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003100190.1 2663250 D 446462 CDS YP_003100191.1 256376531 8326594 2664524..2665408 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 2665408 8326594 Amir_2405 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100191.1 2664524 D 446462 CDS YP_003100192.1 256376532 8326595 2665408..2666238 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL2327 transmembrane component of ABC transporter; ABC transporter inner membrane protein 2666238 8326595 Amir_2406 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100192.1 2665408 D 446462 CDS YP_003100193.1 256376533 8326596 complement(2666269..2666958) 1 NC_013093.1 KEGG: GK24108 gene product from transcript GK24108- RA; hypothetical protein 2666958 8326596 Amir_2407 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100193.1 2666269 R 446462 CDS YP_003100194.1 256376534 8326597 complement(2666955..2667653) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ccs:CCNA_03389 lantibiotic transport ATP- binding protein; ABC transporter 2667653 8326597 Amir_2408 Actinosynnema mirum DSM 43827 ABC transporter YP_003100194.1 2666955 R 446462 CDS YP_003100195.1 256376535 8326598 complement(2667688..2668353) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 2668353 8326598 Amir_2409 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100195.1 2667688 R 446462 CDS YP_003100196.1 256376536 8326599 complement(2668343..2669374) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 2669374 8326599 Amir_2410 Actinosynnema mirum DSM 43827 histidine kinase YP_003100196.1 2668343 R 446462 CDS YP_003100197.1 256376537 8326600 complement(2669404..2669805) 1 NC_013093.1 hypothetical protein 2669805 8326600 Amir_2411 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100197.1 2669404 R 446462 CDS YP_003100198.1 256376538 8326601 complement(2669919..2670635) 1 NC_013093.1 KEGG: bpy:Bphyt_5600 nitroreductase; hypothetical protein 2670635 8326601 Amir_2412 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100198.1 2669919 R 446462 CDS YP_003100199.1 256376539 8326602 2670845..2671405 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2671405 8326602 Amir_2413 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100199.1 2670845 D 446462 CDS YP_003100200.1 256376540 8326603 complement(2671787..2672764) 1 NC_013093.1 PFAM: nitroreductase; KEGG: rce:RC1_3281 hypothetical protein; nitroreductase 2672764 8326603 Amir_2414 Actinosynnema mirum DSM 43827 nitroreductase YP_003100200.1 2671787 R 446462 CDS YP_003100201.1 256376541 8326604 2672942..2673529 1 NC_013093.1 hypothetical protein 2673529 8326604 Amir_2415 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100201.1 2672942 D 446462 CDS YP_003100202.1 256376542 8326605 2673623..2674456 1 NC_013093.1 PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 2674456 8326605 Amir_2416 Actinosynnema mirum DSM 43827 UspA domain-containing protein YP_003100202.1 2673623 D 446462 CDS YP_003100203.1 256376543 8326606 complement(2674578..2675423) 1 NC_013093.1 KEGG: zmo:ZMO1569 pyruvate-formate lyase activating enzyme; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; pyruvate formate-lyase activating enzyme 2675423 8326606 Amir_2417 Actinosynnema mirum DSM 43827 pyruvate formate-lyase activating enzyme YP_003100203.1 2674578 R 446462 CDS YP_003100204.1 256376544 8326607 complement(2675503..2677761) 1 NC_013093.1 KEGG: rru:Rru_A3000 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C- acetyltransferase glycine radical; formate acetyltransferase 2677761 8326607 Amir_2418 Actinosynnema mirum DSM 43827 formate acetyltransferase YP_003100204.1 2675503 R 446462 CDS YP_003100205.1 256376545 8326608 complement(2678072..2680069) 1 NC_013093.1 KEGG: ade:Adeh_0129 methyltransferase type 11; hypothetical protein 2680069 8326608 Amir_2419 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100205.1 2678072 R 446462 CDS YP_003100206.1 256376546 8326609 complement(2680236..2680628) 1 NC_013093.1 hypothetical protein 2680628 8326609 Amir_2420 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100206.1 2680236 R 446462 CDS YP_003100207.1 256376547 8326610 2680859..2690980 1 NC_013093.1 TIGRFAM: hypothetical protein; PFAM: Cna B domain protein; protein of unknown function DUF11; KEGG: colA; Cna B-type domain-containing protein; hypothetical protein 2690980 8326610 Amir_2421 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100207.1 2680859 D 446462 CDS YP_003100208.1 256376548 8326611 complement(2691116..2691808) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rso:RS05498 transcription regulator protein; TetR family transcriptional regulator 2691808 8326611 Amir_2422 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100208.1 2691116 R 446462 CDS YP_003100209.1 256376549 8326612 2691969..2692757 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: scl:sce6363 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 2692757 8326612 Amir_2423 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100209.1 2691969 D 446462 CDS YP_003100210.1 256376550 8326613 2692908..2693117 1 NC_013093.1 hypothetical protein 2693117 8326613 Amir_2424 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100210.1 2692908 D 446462 CDS YP_003100211.1 256376551 8326614 complement(2693123..2694754) 1 NC_013093.1 KEGG: prw:PsycPRwf_0069 cholesterol oxidase; Cholesterol oxidase 2694754 8326614 Amir_2425 Actinosynnema mirum DSM 43827 Cholesterol oxidase YP_003100211.1 2693123 R 446462 CDS YP_003100212.1 256376552 8326615 complement(2694882..2695691) 1 NC_013093.1 PFAM: Ion transport protein; KEGG: tmz:Tmz1t_1575 ion transport protein; Ion transport protein 2695691 8326615 Amir_2426 Actinosynnema mirum DSM 43827 Ion transport protein YP_003100212.1 2694882 R 446462 CDS YP_003100213.1 256376553 8326616 2696045..2696848 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: rlt:Rleg2_6302 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 2696848 8326616 Amir_2427 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003100213.1 2696045 D 446462 CDS YP_003100214.1 256376554 8326617 2696845..2698212 1 NC_013093.1 PFAM: FAD linked oxidase domain protein; KEGG: scl:sce0752 glycolate oxidase; FAD linked oxidase domain-containing protein 2698212 8326617 Amir_2428 Actinosynnema mirum DSM 43827 FAD linked oxidase domain-containing protein YP_003100214.1 2696845 D 446462 CDS YP_003100215.1 256376555 8326618 complement(2698252..2698437) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 2698437 8326618 Amir_2429 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100215.1 2698252 R 446462 CDS YP_003100216.1 256376556 8326619 complement(2698440..2699270) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: rlt:Rleg2_3945 transcriptional regulator, XRE family; XRE family transcriptional regulator 2699270 8326619 Amir_2430 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100216.1 2698440 R 446462 CDS YP_003100217.1 256376557 8326620 2699524..2699967 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2699967 8326620 Amir_2431 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100217.1 2699524 D 446462 CDS YP_003100218.1 256376558 8326621 complement(2699992..2700807) 1 NC_013093.1 hypothetical protein 2700807 8326621 Amir_2432 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100218.1 2699992 R 446462 CDS YP_003100219.1 256376559 8326622 2701011..2701178 1 NC_013093.1 hypothetical protein 2701178 8326622 Amir_2433 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100219.1 2701011 D 446462 CDS YP_003100220.1 256376560 8326623 complement(2701231..2702121) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: nmu:Nmul_A2438 hypothetical protein; hypothetical protein 2702121 8326623 Amir_2434 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100220.1 2701231 R 446462 CDS YP_003100221.1 256376561 8326624 complement(2702403..2703164) 1 NC_013093.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: aba:Acid345_0656 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 2703164 8326624 Amir_2435 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003100221.1 2702403 R 446462 CDS YP_003100222.1 256376562 8326625 2703327..2704814 1 NC_013093.1 PFAM: sodium/hydrogen exchanger; KEGG: mrd:Mrad2831_1143 Na+/H+ antiporter; sodium/hydrogen exchanger 2704814 8326625 Amir_2436 Actinosynnema mirum DSM 43827 sodium/hydrogen exchanger YP_003100222.1 2703327 D 446462 CDS YP_003100223.1 256376563 8326626 complement(2704818..2708651) 1 NC_013093.1 KEGG: rru:Rru_A1270 hypothetical protein; hypothetical protein 2708651 8326626 Amir_2437 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100223.1 2704818 R 446462 CDS YP_003100224.1 256376564 8326627 complement(2708651..2709868) 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: scl:sce7166 DNA repair exonuclease family protein; metallophosphoesterase 2709868 8326627 Amir_2438 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003100224.1 2708651 R 446462 CDS YP_003100225.1 256376565 8326628 2710155..2711507 1 NC_013093.1 KEGG: ade:Adeh_1847 chromosome segregation ATPase; chromosome segregation ATPase 2711507 8326628 Amir_2439 Actinosynnema mirum DSM 43827 chromosome segregation ATPase YP_003100225.1 2710155 D 446462 CDS YP_003100226.1 256376566 8326629 2711510..2712070 1 NC_013093.1 hypothetical protein 2712070 8326629 Amir_2440 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100226.1 2711510 D 446462 CDS YP_003100227.1 256376567 8326630 complement(2712111..2712938) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: bja:bll4873 hypothetical protein; XRE family transcriptional regulator 2712938 8326630 Amir_2441 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100227.1 2712111 R 446462 CDS YP_003100228.1 256376568 8326631 2713056..2713859 1 NC_013093.1 PFAM: siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: jan:Jann_2126 FAD-binding 9, siderophore- interacting; siderophore-interacting protein 2713859 8326631 Amir_2442 Actinosynnema mirum DSM 43827 siderophore-interacting protein YP_003100228.1 2713056 D 446462 CDS YP_003100229.1 256376569 8326632 complement(2713910..2714599) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rpb:RPB_4514 TetR family transcriptional regulator; TetR family transcriptional regulator 2714599 8326632 Amir_2443 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100229.1 2713910 R 446462 CDS YP_003100230.1 256376570 8326633 2714725..2715663 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: ccs:CCNA_02438 quinone oxidoreductase; alcohol dehydrogenase GroES domain-containing protein 2715663 8326633 Amir_2444 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003100230.1 2714725 D 446462 CDS YP_003100231.1 256376571 8326634 2716193..2717641 1 NC_013093.1 KEGG: scl:sce8913 cytochrome P450 CYP109C2; cytochrome P450-like protein 2717641 8326634 Amir_2445 Actinosynnema mirum DSM 43827 cytochrome P450-like protein YP_003100231.1 2716193 D 446462 CDS YP_003100232.1 256376572 8326635 complement(2717664..2718590) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pmy:Pmen_4546 LysR family transcriptional regulator; LysR family transcriptional regulator 2718590 8326635 Amir_2446 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003100232.1 2717664 R 446462 CDS YP_003100233.1 256376573 8326636 2718664..2719629 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: dvm:DvMF_1193 protein of unknown function DUF6 transmembrane; hypothetical protein 2719629 8326636 Amir_2447 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100233.1 2718664 D 446462 CDS YP_003100234.1 256376574 8326637 2719922..2720512 1 NC_013093.1 PFAM: protein of unknown function UPF0016; KEGG: sat:SYN_01349 hypothetical protein; hypothetical protein 2720512 8326637 Amir_2448 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100234.1 2719922 D 446462 CDS YP_003100235.1 256376575 8326638 complement(2720610..2720960) 1 NC_013093.1 hypothetical protein 2720960 8326638 Amir_2449 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100235.1 2720610 R 446462 CDS YP_003100236.1 256376576 8326639 complement(2720974..2721219) 1 NC_013093.1 KEGG: mag:amb4032 hypothetical protein; hypothetical protein 2721219 8326639 Amir_2450 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100236.1 2720974 R 446462 CDS YP_003100237.1 256376577 8326640 2721804..2722385 1 NC_013093.1 hypothetical protein 2722385 8326640 Amir_2451 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100237.1 2721804 D 446462 CDS YP_003100238.1 256376578 8326641 2722414..2722833 1 NC_013093.1 hypothetical protein 2722833 8326641 Amir_2452 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100238.1 2722414 D 446462 CDS YP_003100239.1 256376579 8326642 complement(2722916..2723215) 1 NC_013093.1 KEGG: gbm:Gbem_1185 hypothetical protein; hypothetical protein 2723215 8326642 Amir_2453 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100239.1 2722916 R 446462 CDS YP_003100240.1 256376580 8326643 complement(2723427..2723933) 1 NC_013093.1 PFAM: regulatory protein MarR; transcriptional regulator PadR family protein; SMART: regulatory protein MarR; KEGG: atc:AGR_C_466 hypothetical protein; MarR family transcriptional regulator 2723933 8326643 Amir_2454 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100240.1 2723427 R 446462 CDS YP_003100241.1 256376581 8326644 2723976..2725064 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: reh:H16_A0077 predicted PecM protein; hypothetical protein 2725064 8326644 Amir_2455 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100241.1 2723976 D 446462 CDS YP_003100242.1 256376582 8326645 complement(2724904..2726604) 1 NC_013093.1 PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: rsq:Rsph17025_3273 acetamidase/formamidase; ABC transporter 2726604 8326645 Amir_2456 Actinosynnema mirum DSM 43827 ABC transporter YP_003100242.1 2724904 R 446462 CDS YP_003100243.1 256376583 8326646 complement(2726601..2728289) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: gbe:GbCGDNIH1_0125 amide-UreA binding protein; family 5 extracellular solute-binding protein 2728289 8326646 Amir_2457 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003100243.1 2726601 R 446462 CDS YP_003100244.1 256376584 8326647 complement(2728410..2729405) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsh:Rsph17029_4148 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2729405 8326647 Amir_2458 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100244.1 2728410 R 446462 CDS YP_003100245.1 256376585 8326648 complement(2729405..2730331) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pca:Pcar_1867 ABC-type transport system protein; ABC transporter inner membrane protein 2730331 8326648 Amir_2459 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100245.1 2729405 R 446462 CDS YP_003100246.1 256376586 8326649 2730551..2730916 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: transcriptional regulator, HxlR family; HxlR family transcriptional regulator 2730916 8326649 Amir_2460 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003100246.1 2730551 D 446462 CDS YP_003100247.1 256376587 8326650 2731034..2731993 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: ank:AnaeK_3358 alcohol dehydrogenase zinc- binding domain protein; alcohol dehydrogenase GroES domain-containing protein 2731993 8326650 Amir_2461 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003100247.1 2731034 D 446462 CDS YP_003100248.1 256376588 8326651 2732004..2732276 1 NC_013093.1 hypothetical protein 2732276 8326651 Amir_2462 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100248.1 2732004 D 446462 CDS YP_003100249.1 256376589 8326652 2732315..2733151 1 NC_013093.1 hypothetical protein 2733151 8326652 Amir_2463 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100249.1 2732315 D 446462 CDS YP_003100250.1 256376590 8326653 complement(2733130..2733819) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: rce:RC1_3267 phosphate regulon transcriptional regulatory protein PhoB; winged helix family two component transcriptional regulator 2733819 8326653 Amir_2464 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003100250.1 2733130 R 446462 CDS YP_003100251.1 256376591 8326654 2734048..2735841 1 NC_013093.1 PFAM: histidine kinase A domain protein; ATP- binding region ATPase domain protein; SMART: histidine kinase A domain protein; ATP- binding region ATPase domain protein; KEGG: scl:sce2655 two-component hybrid sensor and regulator; histidine kinase 2735841 8326654 Amir_2465 Actinosynnema mirum DSM 43827 histidine kinase YP_003100251.1 2734048 D 446462 CDS YP_003100252.1 256376592 8326655 2735872..2736234 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sat:SYN_02356 anti-sigma F factor antagonist; anti-sigma-factor antagonist 2736234 8326655 Amir_2466 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003100252.1 2735872 D 446462 CDS YP_003100253.1 256376593 8326656 complement(2737302..2740496) 1 NC_013093.1 PFAM: glycoside hydrolase family 2 sugar binding; PA14 domain protein; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; SMART: PA14 domain protein; LamG domain protein jellyroll fold domain protein; KEGG: sus:Acid_6668 glycoside hydrolase family protein; glycoside hydrolase family protein 2740496 8326656 Amir_2467 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003100253.1 2737302 R 446462 CDS YP_003100254.1 256376594 8326657 complement(2740664..2741857) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: maq:Maqu_2048 major facilitator superfamily transporter; major facilitator superfamily protein 2741857 8326657 Amir_2468 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100254.1 2740664 R 446462 CDS YP_003100255.1 256376595 8326658 complement(2741857..2742531) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: met:M446_5037 GntR family transcriptional regulator; GntR family transcriptional regulator 2742531 8326658 Amir_2469 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003100255.1 2741857 R 446462 CDS YP_003100256.1 256376596 8326659 2742765..2743412 1 NC_013093.1 KEGG: GF15944 gene product from transcript GF15944- RA; hypothetical protein 2743412 8326659 Amir_2470 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100256.1 2742765 D 446462 CDS YP_003100257.1 256376597 8326660 2743541..2744023 1 NC_013093.1 hypothetical protein 2744023 8326660 Amir_2471 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100257.1 2743541 D 446462 CDS YP_003100258.1 256376598 8326661 2744408..2744785 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dvl:Dvul_2983 anti-sigma-factor antagonist; anti-sigma-factor antagonist 2744785 8326661 Amir_2472 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003100258.1 2744408 D 446462 CDS YP_003100259.1 256376599 8326662 2744793..2745863 1 NC_013093.1 PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: dvl:Dvul_0672 peptidase M20; peptidase M20 2745863 8326662 Amir_2473 Actinosynnema mirum DSM 43827 peptidase M20 YP_003100259.1 2744793 D 446462 CDS YP_003100260.1 256376600 8326663 2745993..2746391 1 NC_013093.1 KEGG: afw:Anae109_0106 integral membrane sensor signal transduction histidine kinase; hypothetical protein 2746391 8326663 Amir_2474 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100260.1 2745993 D 446462 CDS YP_003100261.1 256376601 8326664 2746697..2747368 1 NC_013093.1 PFAM: chitin-binding domain 3 protein; KEGG: sml:Smlt4515 cellulose/chitin- binding protein; chitin-binding domain 3 protein 2747368 8326664 Amir_2475 Actinosynnema mirum DSM 43827 chitin-binding domain 3 protein YP_003100261.1 2746697 D 446462 CDS YP_003100262.1 256376602 8326665 2747665..2748669 1 NC_013093.1 PFAM: integral membrane protein TerC; KEGG: csa:Csal_1104 integral membrane protein TerC; integral membrane protein TerC 2748669 8326665 Amir_2476 Actinosynnema mirum DSM 43827 integral membrane protein TerC YP_003100262.1 2747665 D 446462 CDS YP_003100263.1 256376603 8326666 2748907..2749524 1 NC_013093.1 PFAM: isochorismatase hydrolase; KEGG: bid:Bind_1386 isochorismatase hydrolase; isochorismatase hydrolase 2749524 8326666 Amir_2477 Actinosynnema mirum DSM 43827 isochorismatase hydrolase YP_003100263.1 2748907 D 446462 CDS YP_003100264.1 256376604 8326667 2749604..2750794 1 NC_013093.1 PFAM: peptidoglycan-binding domain 1 protein; KEGG: mes:Meso_0085 peptidoglycan-binding domain 1; peptidoglycan-binding domain 1 protein 2750794 8326667 Amir_2478 Actinosynnema mirum DSM 43827 peptidoglycan-binding domain 1 protein YP_003100264.1 2749604 D 446462 CDS YP_003100265.1 256376605 8326668 2751287..2751550 1 NC_013093.1 hypothetical protein 2751550 8326668 Amir_2479 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100265.1 2751287 D 446462 CDS YP_003100266.1 256376606 8326669 complement(2751597..2752313) 1 NC_013093.1 KEGG: rso:RS02209 transmembrane protein; integral membrane protein 2752313 8326669 Amir_2480 Actinosynnema mirum DSM 43827 integral membrane protein YP_003100266.1 2751597 R 446462 CDS YP_003100267.1 256376607 8326670 2752855..2764620 1 NC_013093.1 TIGRFAM: hypothetical protein; PFAM: protein of unknown function DUF11; KEGG: bce:BC1592 cell surface protein; hypothetical protein 2764620 8326670 Amir_2481 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100267.1 2752855 D 446462 CDS YP_003100268.1 256376608 8326671 2764713..2765351 1 NC_013093.1 hypothetical protein 2765351 8326671 Amir_2482 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100268.1 2764713 D 446462 CDS YP_003100269.1 256376609 8326672 2766687..2768600 1 NC_013093.1 KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein 2768600 8326672 Amir_2483 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100269.1 2766687 D 446462 CDS YP_003100270.1 256376610 8326673 complement(2768704..2770383) 1 NC_013093.1 SMART: von Willebrand factor type A; KEGG: dac:Daci_0766 von Willebrand factor type A; von Willebrand factor type A 2770383 8326673 Amir_2484 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003100270.1 2768704 R 446462 CDS YP_003100271.1 256376611 8326674 complement(2770371..2771597) 1 NC_013093.1 KEGG: dac:Daci_0764 hypothetical protein; hypothetical protein 2771597 8326674 Amir_2485 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100271.1 2770371 R 446462 CDS YP_003100272.1 256376612 8326675 complement(2771601..2772374) 1 NC_013093.1 hypothetical protein 2772374 8326675 Amir_2486 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100272.1 2771601 R 446462 CDS YP_003100273.1 256376613 8326676 complement(2772405..2773538) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: ank:AnaeK_0122 serine/threonine protein kinase; serine/threonine protein kinase 2773538 8326676 Amir_2487 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003100273.1 2772405 R 446462 CDS YP_003100274.1 256376614 8326679 2776059..2776721 1 NC_013093.1 KEGG: rce:RC1_0257 puromycin N-acetyltransferase; hypothetical protein 2776721 8326679 Amir_2490 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100274.1 2776059 D 446462 CDS YP_003100275.1 256376615 8326680 complement(2776775..2777878) 1 NC_013093.1 KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 2777878 8326680 Amir_2491 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100275.1 2776775 R 446462 CDS YP_003100276.1 256376616 8326681 2778236..2780008 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: eca:ECA1488 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 2780008 8326681 Amir_2492 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003100276.1 2778236 D 446462 CDS YP_003100277.1 256376617 8326682 2780680..2787840 1 NC_013093.1 PFAM: beta-ketoacyl synthase; acyl transferase; KR domain protein; short-chain dehydrogenase/reductase SDR; 2- nitropropane dioxygenase NPD; phosphopantetheine-binding; KEGG: sus:Acid_1972 beta-ketoacyl synthase; erythronolide synthase 2787840 8326682 Amir_2493 Actinosynnema mirum DSM 43827 erythronolide synthase YP_003100277.1 2780680 D 446462 CDS YP_003100278.1 256376618 8326683 2787837..2792198 1 NC_013093.1 PFAM: beta-ketoacyl synthase; acyl transferase; 4'- phosphopantetheinyl transferase; KEGG: sus:Acid_1973 beta-ketoacyl synthase; beta-ketoacyl synthase 2792198 8326683 Amir_2494 Actinosynnema mirum DSM 43827 beta-ketoacyl synthase YP_003100278.1 2787837 D 446462 CDS YP_003100279.1 256376619 8326684 2792195..2792509 1 NC_013093.1 KEGG: pub:SAR11_0708 acyl carrier protein (ACP); hypothetical protein 2792509 8326684 Amir_2495 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100279.1 2792195 D 446462 CDS YP_003100280.1 256376620 8326685 2792506..2793339 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: azc:AZC_1444 beta-ketoadipate enol-lactone hydrolase protein; alpha/beta hydrolase fold protein 2793339 8326685 Amir_2496 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003100280.1 2792506 D 446462 CDS YP_003100281.1 256376621 8326686 2793336..2794478 1 NC_013093.1 TIGRFAM: glycosyltransferase, MGT family; PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; KEGG: bcm:Bcenmc03_1778 glycosyl transferase family protein; MGT family glycosyltransferase 2794478 8326686 Amir_2497 Actinosynnema mirum DSM 43827 MGT family glycosyltransferase YP_003100281.1 2793336 D 446462 CDS YP_003100282.1 256376622 8326687 2794856..2796643 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rce:RC1_1837 ABC transporter, ATP-binding; ABC transporter 2796643 8326687 Amir_2498 Actinosynnema mirum DSM 43827 ABC transporter YP_003100282.1 2794856 D 446462 CDS YP_003100283.1 256376623 8326688 complement(2796627..2797445) 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: nar:Saro_1805 hypothetical protein; G-D-S-L family lipolytic protein 2797445 8326688 Amir_2499 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003100283.1 2796627 R 446462 CDS YP_003100284.1 256376624 8326689 2797651..2799537 1 NC_013093.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mxa:MXAN_0345 N-acetylmuramoyl-L- alanine amidase; N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD 2799537 8326689 Amir_2500 Actinosynnema mirum DSM 43827 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD YP_003100284.1 2797651 D 446462 CDS YP_003100285.1 256376625 8326690 2799627..2800091 1 NC_013093.1 SMART: CHRD domain containing protein; KEGG: scl:sce5878 hypothetical protein; CHRD domain containing protein 2800091 8326690 Amir_2501 Actinosynnema mirum DSM 43827 CHRD domain containing protein YP_003100285.1 2799627 D 446462 CDS YP_003100286.1 256376626 8326691 2800252..2800797 1 NC_013093.1 hypothetical protein 2800797 8326691 Amir_2502 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100286.1 2800252 D 446462 CDS YP_003100287.1 256376627 8326692 2800895..2801263 1 NC_013093.1 PFAM: YCII-related; KEGG: scl:sce5148 hypothetical protein; YCII-like protein 2801263 8326692 Amir_2503 Actinosynnema mirum DSM 43827 YCII-like protein YP_003100287.1 2800895 D 446462 CDS YP_003100288.1 256376628 8326693 2801278..2802510 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: sus:Acid_3701 RNA polymerase ECF-subfamily sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 2802510 8326693 Amir_2504 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003100288.1 2801278 D 446462 CDS YP_003100289.1 256376629 8326694 complement(2802500..2803240) 1 NC_013093.1 KEGG: scl:sce4774 peptidase M10A; peptidase M10A 2803240 8326694 Amir_2505 Actinosynnema mirum DSM 43827 peptidase M10A YP_003100289.1 2802500 R 446462 CDS YP_003100290.1 256376630 8326695 complement(2803691..2805142) 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: bcm:Bcenmc03_6120 aldehyde dehydrogenase; aldehyde dehydrogenase 2805142 8326695 Amir_2506 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003100290.1 2803691 R 446462 CDS YP_003100291.1 256376631 8326696 2805587..2806441 1 NC_013093.1 hypothetical protein 2806441 8326696 Amir_2507 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100291.1 2805587 D 446462 CDS YP_003100292.1 256376632 8326697 2806438..2811342 1 NC_013093.1 KEGG: acp:A2cp1_3940 hypothetical protein; hypothetical protein 2811342 8326697 Amir_2508 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100292.1 2806438 D 446462 CDS YP_003100293.1 256376633 8326698 2811339..2816237 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2816237 8326698 Amir_2509 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100293.1 2811339 D 446462 CDS YP_003100294.1 256376634 8326699 2816234..2821168 1 NC_013093.1 KEGG: MUC17; mucin 17, cell surface associated; hypothetical protein 2821168 8326699 Amir_2510 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100294.1 2816234 D 446462 CDS YP_003100295.1 256376635 8326700 2821165..2822322 1 NC_013093.1 PFAM: ATPase associated with various cellular activities AAA_5; ATPase associated with various cellular activities AAA_3; SMART: ATPase AAA; KEGG: mrd:Mrad2831_1397 ATPase; ATPase 2822322 8326700 Amir_2511 Actinosynnema mirum DSM 43827 ATPase YP_003100295.1 2821165 D 446462 CDS YP_003100296.1 256376636 8326701 2822336..2826223 1 NC_013093.1 PFAM: VWA containing CoxE family protein; KEGG: ecs:ECs2930 hypothetical protein; VWA containing CoxE family protein 2826223 8326701 Amir_2512 Actinosynnema mirum DSM 43827 VWA containing CoxE family protein YP_003100296.1 2822336 D 446462 CDS YP_003100297.1 256376637 8326702 2826220..2827986 1 NC_013093.1 KEGG: mrd:Mrad2831_1392 zinc finger SWIM domain- containing protein; hypothetical protein 2827986 8326702 Amir_2513 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100297.1 2826220 D 446462 CDS YP_003100298.1 256376638 8326703 2828329..2829081 1 NC_013093.1 hypothetical protein 2829081 8326703 Amir_2514 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100298.1 2828329 D 446462 CDS YP_003100299.1 256376639 8326704 complement(2829103..2829990) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce1222 AraC-like transcription regulator; AraC family transcriptional regulator 2829990 8326704 Amir_2515 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003100299.1 2829103 R 446462 CDS YP_003100300.1 256376640 8326705 complement(2830263..2830820) 1 NC_013093.1 PFAM: DoxX family protein; KEGG: mes:Meso_2920 DoxX; DoxX family protein 2830820 8326705 Amir_2516 Actinosynnema mirum DSM 43827 DoxX family protein YP_003100300.1 2830263 R 446462 CDS YP_003100301.1 256376641 8326706 2831131..2833398 1 NC_013093.1 PFAM: Catalase domain protein; KEGG: psa:PST_0039 hydroperoxidase II; Catalase 2833398 8326706 Amir_2517 Actinosynnema mirum DSM 43827 Catalase YP_003100301.1 2831131 D 446462 CDS YP_003100302.1 256376642 8326707 2833648..2834103 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: hypothetical protein; endoribonuclease L-PSP 2834103 8326707 Amir_2518 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003100302.1 2833648 D 446462 CDS YP_003100303.1 256376643 8326708 complement(2834125..2834976) 1 NC_013093.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: phenazine biosynthesis PhzC/PhzF protein; KEGG: psb:Psyr_3359 phenazine biosynthesis PhzC/PhzF protein; phenazine biosynthesis protein PhzF family 2834976 8326708 Amir_2519 Actinosynnema mirum DSM 43827 phenazine biosynthesis protein PhzF family YP_003100303.1 2834125 R 446462 CDS YP_003100304.1 256376644 8326709 complement(2835009..2835860) 1 NC_013093.1 SMART: prolyl 4-hydroxylase alpha subunit; KEGG: bha:BH2933 hypothetical protein; prolyl 4-hydroxylase alpha subunit 2835860 8326709 Amir_2520 Actinosynnema mirum DSM 43827 prolyl 4-hydroxylase alpha subunit YP_003100304.1 2835009 R 446462 CDS YP_003100305.1 256376645 8326710 complement(2835963..2836151) 1 NC_013093.1 hypothetical protein 2836151 8326710 Amir_2521 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100305.1 2835963 R 446462 CDS YP_003100306.1 256376646 8326711 complement(2836290..2839166) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: hypothetical protein; hypothetical protein 2839166 8326711 Amir_2522 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100306.1 2836290 R 446462 CDS YP_003100307.1 256376647 8326712 complement(2839358..2841013) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bph:Bphy_3357 EmrB/QacA family drug resistance transporter; major facilitator superfamily protein 2841013 8326712 Amir_2523 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100307.1 2839358 R 446462 CDS YP_003100308.1 256376648 8326713 complement(2841010..2841495) 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: ppw:PputW619_3117 MarR family transcriptional regulator; MarR family transcriptional regulator 2841495 8326713 Amir_2524 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100308.1 2841010 R 446462 CDS YP_003100309.1 256376649 8326714 2841606..2842208 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: transcriptional regulator protein; TetR family transcriptional regulator 2842208 8326714 Amir_2525 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100309.1 2841606 D 446462 CDS YP_003100310.1 256376650 8326715 2842333..2843328 1 NC_013093.1 PFAM: intradiol ring-cleavage dioxygenase; KEGG: dac:Daci_3143 intradiol ring-cleavage dioxygenase; intradiol ring-cleavage dioxygenase 2843328 8326715 Amir_2526 Actinosynnema mirum DSM 43827 intradiol ring-cleavage dioxygenase YP_003100310.1 2842333 D 446462 CDS YP_003100311.1 256376651 8326717 2844590..2845471 1 NC_013093.1 PFAM: transcription activator effector binding; regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcb:BCB4264_A2545 transcriptional regulator, MerR family; MerR family transcriptional regulator 2845471 8326717 Amir_2528 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003100311.1 2844590 D 446462 CDS YP_003100312.1 256376652 8326718 complement(2845611..2848967) 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: xcb:XC_4140 hypothetical protein; metallophosphoesterase 2848967 8326718 Amir_2529 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003100312.1 2845611 R 446462 CDS YP_003100313.1 256376653 8326719 2849112..2850677 1 NC_013093.1 KEGG: mxa:MXAN_5493 WD domain G-beta repeat protein; hypothetical protein 2850677 8326719 Amir_2530 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100313.1 2849112 D 446462 CDS YP_003100314.1 256376654 8326720 2850763..2853039 1 NC_013093.1 PFAM: tyrosine protein kinase; SMART: serine/threonine protein kinase; KEGG: scl:sce5109 protein kinase; serine/threonine protein kinase 2853039 8326720 Amir_2531 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003100314.1 2850763 D 446462 CDS YP_003100315.1 256376655 8326721 2853120..2854514 1 NC_013093.1 PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: mpo:Mpop_1395 LPXTG-motif cell wall anchor domain protein; von Willebrand factor type A 2854514 8326721 Amir_2532 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003100315.1 2853120 D 446462 CDS YP_003100316.1 256376656 8326722 2854511..2855647 1 NC_013093.1 KEGG: GK23348 gene product from transcript GK23348- RA; hypothetical protein 2855647 8326722 Amir_2533 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100316.1 2854511 D 446462 CDS YP_003100317.1 256376657 8326723 2855727..2856941 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: ret:RHE_CH00696 alpha-glucoside ABC transporter, substrate-binding protein; family 1 extracellular solute-binding protein 2856941 8326723 Amir_2534 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003100317.1 2855727 D 446462 CDS YP_003100318.1 256376658 8326724 2857177..2858448 1 NC_013093.1 PFAM: cytochrome P450; KEGG: hypothetical protein; cytochrome P450 2858448 8326724 Amir_2535 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100318.1 2857177 D 446462 CDS YP_003100319.1 256376659 8326725 complement(2858482..2859270) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr7343 short-chain dehydrogenase; short-chain dehydrogenase/reductase SDR 2859270 8326725 Amir_2536 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100319.1 2858482 R 446462 CDS YP_003100320.1 256376660 8326726 2859347..2860582 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: efe:EFER_2257 lactose/glucose efflux system; major facilitator superfamily protein 2860582 8326726 Amir_2537 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100320.1 2859347 D 446462 CDS YP_003100321.1 256376661 8326727 2860636..2861100 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: mag:amb1485 transcriptional regulator; MarR family transcriptional regulator 2861100 8326727 Amir_2538 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100321.1 2860636 D 446462 CDS YP_003100322.1 256376662 8326728 complement(2861017..2861829) 1 NC_013093.1 KEGG: hypothetical protein LOC743833; hypothetical protein 2861829 8326728 Amir_2539 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100322.1 2861017 R 446462 CDS YP_003100323.1 256376663 8326729 complement(2861875..2865831) 1 NC_013093.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: ABR142Wp; K01529; DEAD/DEAH box helicase domain-containing protein 2865831 8326729 Amir_2540 Actinosynnema mirum DSM 43827 DEAD/DEAH box helicase domain-containing protein YP_003100323.1 2861875 R 446462 CDS YP_003100324.1 256376664 8326730 complement(2865926..2866402) 1 NC_013093.1 KEGG: hch:HCH_03911 hypothetical protein; hypothetical protein 2866402 8326730 Amir_2541 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100324.1 2865926 R 446462 CDS YP_003100325.1 256376665 8326731 2866515..2866982 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: aha:AHA_0491 AsnC family transcriptional regulator; AsnC family transcriptional regulator 2866982 8326731 Amir_2542 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003100325.1 2866515 D 446462 CDS YP_003100326.1 256376666 8326732 2866979..2867818 1 NC_013093.1 KEGG: scl:sce1853 hypothetical protein; hypothetical protein 2867818 8326732 Amir_2543 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100326.1 2866979 D 446462 CDS YP_003100327.1 256376667 8326733 2867902..2868957 1 NC_013093.1 hypothetical protein 2868957 8326733 Amir_2544 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100327.1 2867902 D 446462 CDS YP_003100328.1 256376668 8326734 complement(2868954..2869808) 1 NC_013093.1 hypothetical protein 2869808 8326734 Amir_2545 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100328.1 2868954 R 446462 CDS YP_003100329.1 256376669 8326735 complement(2869873..2870685) 1 NC_013093.1 hypothetical protein 2870685 8326735 Amir_2546 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100329.1 2869873 R 446462 CDS YP_003100330.1 256376670 8326736 2870880..2871998 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2871998 8326736 Amir_2547 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100330.1 2870880 D 446462 CDS YP_003100331.1 256376671 8326737 complement(2872074..2875160) 1 NC_013093.1 PFAM: acriflavin resistance protein; KEGG: bcb:BCB4264_A5560 transporter, AcrB/AcrD/AcrF family; acriflavin resistance protein 2875160 8326737 Amir_2548 Actinosynnema mirum DSM 43827 acriflavin resistance protein YP_003100331.1 2872074 R 446462 CDS YP_003100332.1 256376672 8326738 complement(2875524..2876480) 1 NC_013093.1 KEGG: afw:Anae109_0827 hypothetical protein; hypothetical protein 2876480 8326738 Amir_2549 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100332.1 2875524 R 446462 CDS YP_003100333.1 256376673 8326739 2876782..2877396 1 NC_013093.1 KEGG: AGAP007349-PA; hypothetical protein 2877396 8326739 Amir_2550 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100333.1 2876782 D 446462 CDS YP_003100334.1 256376674 8326740 2877509..2878942 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_1465 major facilitator transporter; major facilitator superfamily protein 2878942 8326740 Amir_2551 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100334.1 2877509 D 446462 CDS YP_003100335.1 256376675 8326741 2879043..2879540 1 NC_013093.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: scl:sce6060 hypothetical protein; Activator of Hsp90 ATPase 1 family protein 2879540 8326741 Amir_2552 Actinosynnema mirum DSM 43827 Activator of Hsp90 ATPase 1 family protein YP_003100335.1 2879043 D 446462 CDS YP_003100336.1 256376676 8326742 2879792..2880706 1 NC_013093.1 PFAM: cytochrome oxidase assembly; KEGG: tgr:Tgr7_3001 cytochrome oxidase assembly; cytochrome oxidase assembly 2880706 8326742 Amir_2553 Actinosynnema mirum DSM 43827 cytochrome oxidase assembly YP_003100336.1 2879792 D 446462 CDS YP_003100337.1 256376677 8326743 2880725..2881183 1 NC_013093.1 KEGG: sf3a2; splicing factor 3a, subunit 2, 66kDa; hypothetical protein 2881183 8326743 Amir_2554 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100337.1 2880725 D 446462 CDS YP_003100338.1 256376678 8326744 2881596..2883752 1 NC_013093.1 KEGG: met:M446_2712 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; diguanylate cyclase/phosphodiesterase 2883752 8326744 Amir_2555 Actinosynnema mirum DSM 43827 diguanylate cyclase/phosphodiesterase YP_003100338.1 2881596 D 446462 CDS YP_003100339.1 256376679 8326745 complement(2884677..2885825) 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: dsh:Dshi_3592 Cna B domain-containing protein; Ricin B lectin 2885825 8326745 Amir_2556 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003100339.1 2884677 R 446462 CDS YP_003100340.1 256376680 8326746 complement(2886075..2886635) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: ank:AnaeK_2446 transcriptional regulator, TetR family; TetR family transcriptional regulator 2886635 8326746 Amir_2557 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100340.1 2886075 R 446462 CDS YP_003100341.1 256376681 8326747 2886739..2887677 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ank:AnaeK_2445 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 2887677 8326747 Amir_2558 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100341.1 2886739 D 446462 CDS YP_003100342.1 256376682 8326748 2887995..2888852 1 NC_013093.1 KEGG: bpt:Bpet3133 translation initiation factor IF- 2; hypothetical protein 2888852 8326748 Amir_2559 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100342.1 2887995 D 446462 CDS YP_003100343.1 256376683 8326749 complement(2888928..2890898) 1 NC_013093.1 PFAM: Ricin B lectin; KEGG: scl:sce0966 hypothetical protein; Ricin B lectin 2890898 8326749 Amir_2560 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003100343.1 2888928 R 446462 CDS YP_003100344.1 256376684 8326750 2891609..2894212 1 NC_013093.1 KEGG: pap:PSPA7_4431 hypothetical protein; hypothetical protein 2894212 8326750 Amir_2561 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100344.1 2891609 D 446462 CDS YP_003100345.1 256376685 8326751 2894209..2895429 1 NC_013093.1 KEGG: rde:RD1_A0036 hypothetical protein; hypothetical protein 2895429 8326751 Amir_2562 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100345.1 2894209 D 446462 CDS YP_003100346.1 256376686 8326752 complement(2895511..2896290) 1 NC_013093.1 PFAM: pectate lyase; KEGG: hypothetical protein; pectate lyase 2896290 8326752 Amir_2563 Actinosynnema mirum DSM 43827 pectate lyase YP_003100346.1 2895511 R 446462 CDS YP_003100347.1 256376687 8326753 complement(2896500..2897438) 1 NC_013093.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: atc:AGR_L_1807 hypothetical protein; ornithine cyclodeaminase 2897438 8326753 Amir_2564 Actinosynnema mirum DSM 43827 ornithine cyclodeaminase YP_003100347.1 2896500 R 446462 CDS YP_003100348.1 256376688 8326754 complement(2897414..2898508) 1 NC_013093.1 PFAM: alanine racemase domain protein; KEGG: atc:AGR_L_1808 hypothetical protein; alanine racemase domain-containing protein 2898508 8326754 Amir_2565 Actinosynnema mirum DSM 43827 alanine racemase domain-containing protein YP_003100348.1 2897414 R 446462 CDS YP_003100349.1 256376689 8326755 complement(2898505..2899167) 1 NC_013093.1 PFAM: YheO domain protein; KEGG: pfl:PFL_2666 hypothetical protein; YheO domain-containing protein 2899167 8326755 Amir_2566 Actinosynnema mirum DSM 43827 YheO domain-containing protein YP_003100349.1 2898505 R 446462 CDS YP_003100350.1 256376690 8326756 2899280..2900359 1 NC_013093.1 KEGG: bxe:Bxe_A2027 acyl-CoA dehydrogenase- related protein; acyl-CoA dehydrogenase-like protein 2900359 8326756 Amir_2567 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase-like protein YP_003100350.1 2899280 D 446462 CDS YP_003100351.1 256376691 8326757 2900344..2901627 1 NC_013093.1 PFAM: LmbE family protein; methyltransferase type 11; NodS family protein; methyltransferase type 12; KEGG: psb:Psyr_3000 methyltransferase; LmbE family protein 2901627 8326757 Amir_2568 Actinosynnema mirum DSM 43827 LmbE family protein YP_003100351.1 2900344 D 446462 CDS YP_003100352.1 256376692 8326758 2901624..2902307 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: xcb:XC_2588 glycosyl transferase-related protein; family 2 glycosyl transferase 2902307 8326758 Amir_2569 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003100352.1 2901624 D 446462 CDS YP_003100353.1 256376693 8326759 complement(2902364..2902942) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hypothetical protein; GCN5-like N-acetyltransferase 2902942 8326759 Amir_2570 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003100353.1 2902364 R 446462 CDS YP_003100354.1 256376694 8326760 complement(2903217..2904017) 1 NC_013093.1 PFAM: pectate lyase; KEGG: hypothetical protein; pectate lyase 2904017 8326760 Amir_2571 Actinosynnema mirum DSM 43827 pectate lyase YP_003100354.1 2903217 R 446462 CDS YP_003100355.1 256376695 8326761 2904504..2905340 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mca:MCA1942 sugar ABC transporter, permease protein; ABC transporter inner membrane protein 2905340 8326761 Amir_2572 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100355.1 2904504 D 446462 CDS YP_003100356.1 256376696 8326762 2905348..2906199 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smt:Smal_2681 monosaccharide-transporting ATPase; ABC transporter inner membrane protein 2906199 8326762 Amir_2573 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100356.1 2905348 D 446462 CDS YP_003100357.1 256376697 8326763 2906250..2907599 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1924 sugar transport system (sugar- binding protein); family 1 extracellular solute-binding protein 2907599 8326763 Amir_2574 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003100357.1 2906250 D 446462 CDS YP_003100358.1 256376698 8326764 2907684..2909222 1 NC_013093.1 PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: vei:Veis_3457 alpha-N-arabinofuranosidase; alpha-N-arabinofuranosidase 2909222 8326764 Amir_2575 Actinosynnema mirum DSM 43827 alpha-N-arabinofuranosidase YP_003100358.1 2907684 D 446462 CDS YP_003100359.1 256376699 8326765 2909215..2910954 1 NC_013093.1 PFAM: glycoside hydrolase family 35; glycoside hydrolase family 42 domain protein; KEGG: glb1l; galactosidase, beta 1-like; beta-galactosidase 2910954 8326765 Amir_2576 Actinosynnema mirum DSM 43827 beta-galactosidase YP_003100359.1 2909215 D 446462 CDS YP_003100360.1 256376700 8326766 2911112..2912152 1 NC_013093.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: scl:sce3081 lactose operon repressor; LacI family transcriptional regulator 2912152 8326766 Amir_2577 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003100360.1 2911112 D 446462 CDS YP_003100361.1 256376701 8326767 complement(2912272..2913534) 1 NC_013093.1 hypothetical protein 2913534 8326767 Amir_2578 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100361.1 2912272 R 446462 CDS YP_003100362.1 256376702 8326768 complement(2913527..2914147) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: dal:Dalk_4824 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 2914147 8326768 Amir_2579 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003100362.1 2913527 R 446462 CDS YP_003100363.1 256376703 8326769 2914411..2918286 1 NC_013093.1 KEGG: SL44-1; basic proline-rich protein; hypothetical protein 2918286 8326769 Amir_2580 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100363.1 2914411 D 446462 CDS YP_003100364.1 256376704 8326770 2918303..2919166 1 NC_013093.1 hypothetical protein 2919166 8326770 Amir_2581 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100364.1 2918303 D 446462 CDS YP_003100365.1 256376705 8326771 2919258..2919707 1 NC_013093.1 hypothetical protein 2919707 8326771 Amir_2582 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100365.1 2919258 D 446462 CDS YP_003100366.1 256376706 8326772 2919747..2920181 1 NC_013093.1 hypothetical protein 2920181 8326772 Amir_2583 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100366.1 2919747 D 446462 CDS YP_003100367.1 256376707 8326773 2920691..2920951 1 NC_013093.1 hypothetical protein 2920951 8326773 Amir_2584 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100367.1 2920691 D 446462 CDS YP_003100368.1 256376708 8326774 2921297..2921926 1 NC_013093.1 KEGG: ank:AnaeK_0087 hypothetical protein; hypothetical protein 2921926 8326774 Amir_2585 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100368.1 2921297 D 446462 CDS YP_003100369.1 256376709 8326775 complement(2922003..2923367) 1 NC_013093.1 KEGG: XylD; endoxylanase D; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase 2923367 8326775 Amir_2586 Actinosynnema mirum DSM 43827 endo-1,4-beta-xylanase YP_003100369.1 2922003 R 446462 CDS YP_003100370.1 256376710 8326776 2923630..2925090 1 NC_013093.1 PFAM: propeptide PepSY amd peptidase M4; PepSY- associated TM helix domain protein; KEGG: psb:Psyr_2687 PepSY-associated TM helix; propeptide PepSY amd peptidase M4 2925090 8326776 Amir_2587 Actinosynnema mirum DSM 43827 propeptide PepSY amd peptidase M4 YP_003100370.1 2923630 D 446462 CDS YP_003100371.1 256376711 8326777 2925087..2925698 1 NC_013093.1 KEGG: acp:A2cp1_3455 tetratricopeptide TPR_2 repeat protein; hypothetical protein 2925698 8326777 Amir_2588 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100371.1 2925087 D 446462 CDS YP_003100372.1 256376712 8326778 2925905..2926495 1 NC_013093.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: kpe:KPK_3281 tetracycline repressor protein class A from transposon 1721; TetR family transcriptional regulator 2926495 8326778 Amir_2589 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100372.1 2925905 D 446462 CDS YP_003100373.1 256376713 8326779 2926751..2927077 1 NC_013093.1 hypothetical protein 2927077 8326779 Amir_2590 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100373.1 2926751 D 446462 CDS YP_003100374.1 256376714 8326780 2927082..2927324 1 NC_013093.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; ATP-dependent Clp protease adaptor protein ClpS 2927324 8326780 Amir_2591 Actinosynnema mirum DSM 43827 ATP-dependent Clp protease adaptor protein ClpS YP_003100374.1 2927082 D 446462 CDS YP_003100375.1 256376715 8326781 2927321..2927806 1 NC_013093.1 hypothetical protein 2927806 8326781 Amir_2592 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100375.1 2927321 D 446462 CDS YP_003100376.1 256376716 8326782 2927890..2928405 1 NC_013093.1 PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; KEGG: reu:Reut_A1417 Appr-1-p processing; Appr-1-p processing domain-containing protein 2928405 8326782 Amir_2593 Actinosynnema mirum DSM 43827 Appr-1-p processing domain-containing protein YP_003100376.1 2927890 D 446462 CDS YP_003100377.1 256376717 8326783 complement(2928470..2929108) 1 NC_013093.1 PFAM: DSBA oxidoreductase; KEGG: scl:sce1376 DSBA oxidoreductase; DSBA oxidoreductase 2929108 8326783 Amir_2594 Actinosynnema mirum DSM 43827 DSBA oxidoreductase YP_003100377.1 2928470 R 446462 CDS YP_003100378.1 256376718 8326784 complement(2929099..2929221) 1 NC_013093.1 hypothetical protein 2929221 8326784 Amir_2595 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100378.1 2929099 R 446462 CDS YP_003100379.1 256376719 8326785 2929460..2931043 1 NC_013093.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bpe:BP2620 membrane efflux protein; EmrB/QacA subfamily drug resistance transporter 2931043 8326785 Amir_2596 Actinosynnema mirum DSM 43827 EmrB/QacA subfamily drug resistance transporter YP_003100379.1 2929460 D 446462 CDS YP_003100380.1 256376720 8326786 2931234..2931890 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: pla:Plav_0388 TetR family transcriptional regulator; TetR family transcriptional regulator 2931890 8326786 Amir_2597 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100380.1 2931234 D 446462 CDS YP_003100381.1 256376721 8326787 2932477..2932887 1 NC_013093.1 hypothetical protein 2932887 8326787 Amir_2598 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100381.1 2932477 D 446462 CDS YP_003100382.1 256376722 8326788 2932884..2933285 1 NC_013093.1 PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sus:Acid_1594 GntR family transcriptional regulator; GntR family transcriptional regulator 2933285 8326788 Amir_2599 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003100382.1 2932884 D 446462 CDS YP_003100383.1 256376723 8326789 complement(2933340..2934743) 1 NC_013093.1 KEGG: hypothetical protein LOC100018482; hypothetical protein 2934743 8326789 Amir_2600 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100383.1 2933340 R 446462 CDS YP_003100384.1 256376724 8326790 complement(2934763..2934903) 1 NC_013093.1 hypothetical protein 2934903 8326790 Amir_2601 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100384.1 2934763 R 446462 CDS YP_003100385.1 256376725 8326791 complement(2934896..2935165) 1 NC_013093.1 PFAM: Sigma-70 region 4 type 2; KEGG: ajs:Ajs_2554 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 2935165 8326791 Amir_2602 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003100385.1 2934896 R 446462 CDS YP_003100386.1 256376726 8326792 complement(2935187..2935453) 1 NC_013093.1 PFAM: sigma-70 region 2 domain protein; KEGG: scl:sce6054 ECF family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 2935453 8326792 Amir_2603 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003100386.1 2935187 R 446462 CDS YP_003100387.1 256376727 8326794 complement(2936321..2937337) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: tgr:Tgr7_0733 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 2937337 8326794 Amir_2605 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003100387.1 2936321 R 446462 CDS YP_003100388.1 256376728 8326795 complement(2937510..2937896) 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist 2937896 8326795 Amir_2606 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003100388.1 2937510 R 446462 CDS YP_003100389.1 256376729 8326796 complement(2938060..2938791) 1 NC_013093.1 PFAM: ANTAR domain protein; KEGG: mpo:Mpop_5014 response regulator receiver and ANTAR domain protein; ANTAR domain-containing protein with unknown sensor 2938791 8326796 Amir_2607 Actinosynnema mirum DSM 43827 ANTAR domain-containing protein with unknown sensor YP_003100389.1 2938060 R 446462 CDS YP_003100390.1 256376730 8326797 complement(2939083..2939847) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cak:Caul_1958 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 2939847 8326797 Amir_2608 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100390.1 2939083 R 446462 CDS YP_003100391.1 256376731 8326798 2939926..2940540 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: gdi:GDI0313 TetR family transcriptional regulator; TetR family transcriptional regulator 2940540 8326798 Amir_2609 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100391.1 2939926 D 446462 CDS YP_003100392.1 256376732 8326799 complement(2940611..2941480) 1 NC_013093.1 PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: scl:sce0163 hypothetical protein; Extradiol ring-cleavage dioxygenase class III protein subunit B 2941480 8326799 Amir_2610 Actinosynnema mirum DSM 43827 Extradiol ring-cleavage dioxygenase class III protein subunit B YP_003100392.1 2940611 R 446462 CDS YP_003100393.1 256376733 8326800 complement(2941480..2942319) 1 NC_013093.1 PFAM: NmrA family protein; dTDP-4-dehydrorhamnose reductase; KEGG: mxa:MXAN_5100 NmrA family protein; NmrA family protein 2942319 8326800 Amir_2611 Actinosynnema mirum DSM 43827 NmrA family protein YP_003100393.1 2941480 R 446462 CDS YP_003100394.1 256376734 8326801 complement(2942367..2942849) 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bpt:Bpet2994 MarR family transcriptional regulator; MarR family transcriptional regulator 2942849 8326801 Amir_2612 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100394.1 2942367 R 446462 CDS YP_003100395.1 256376735 8326802 2942947..2944971 1 NC_013093.1 hypothetical protein 2944971 8326802 Amir_2613 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100395.1 2942947 D 446462 CDS YP_003100396.1 256376736 8326803 complement(2945111..2946313) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 2946313 8326803 Amir_2614 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100396.1 2945111 R 446462 CDS YP_003100397.1 256376737 8326804 2946424..2947074 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: cak:Caul_4437 TetR family transcriptional regulator; TetR family transcriptional regulator 2947074 8326804 Amir_2615 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100397.1 2946424 D 446462 CDS YP_003100398.1 256376738 8326805 2947636..2949258 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mrd:Mrad2831_2095 ABC transporter; ABC transporter 2949258 8326805 Amir_2616 Actinosynnema mirum DSM 43827 ABC transporter YP_003100398.1 2947636 D 446462 CDS YP_003100399.1 256376739 8326807 complement(2949727..2950524) 1 NC_013093.1 KEGG: mxa:MXAN_6120 hypothetical protein; hypothetical protein 2950524 8326807 Amir_2618 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100399.1 2949727 R 446462 CDS YP_003100400.1 256376740 8326808 2950632..2950937 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: rpd:RPD_3981 helix-turn-helix, type 11; ArsR family transcriptional regulator 2950937 8326808 Amir_2619 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003100400.1 2950632 D 446462 CDS YP_003100401.1 256376741 8326809 2950934..2951320 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppw:PputW619_2963 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2951320 8326809 Amir_2620 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003100401.1 2950934 D 446462 CDS YP_003100402.1 256376742 8326810 complement(2951358..2952320) 1 NC_013093.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: pat:Patl_3506 inosine/uridine-preferring nucleoside hydrolase; Inosine/uridine-preferring nucleoside hydrolase 2952320 8326810 Amir_2621 Actinosynnema mirum DSM 43827 Inosine/uridine-preferring nucleoside hydrolase YP_003100402.1 2951358 R 446462 CDS YP_003100403.1 256376743 8326811 complement(2952595..2954967) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; riboflavin kinase; flavin reductase domain protein FMN- binding; KEGG: xfa:XF1765 drug:proton antiporter; major facilitator superfamily protein 2954967 8326811 Amir_2622 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100403.1 2952595 R 446462 CDS YP_003100404.1 256376744 8326812 complement(2954964..2956298) 1 NC_013093.1 KEGG: mms:mma_3466 xenobiotic compound monooxygenase A subunit; xenobiotic compound monooxygenase A subunit 2956298 8326812 Amir_2623 Actinosynnema mirum DSM 43827 xenobiotic compound monooxygenase A subunit YP_003100404.1 2954964 R 446462 CDS YP_003100405.1 256376745 8326813 complement(2956295..2956975) 1 NC_013093.1 PFAM: isochorismatase hydrolase; KEGG: pla:Plav_0992 isochorismatase hydrolase; isochorismatase hydrolase 2956975 8326813 Amir_2624 Actinosynnema mirum DSM 43827 isochorismatase hydrolase YP_003100405.1 2956295 R 446462 CDS YP_003100406.1 256376746 8326814 complement(2956975..2958036) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: ccs:CCNA_01227 nitrilotriacetate monooxygenase; luciferase-like monooxygenase 2958036 8326814 Amir_2625 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100406.1 2956975 R 446462 CDS YP_003100407.1 256376747 8326815 complement(2958083..2959228) 1 NC_013093.1 PFAM: NMT1/THI5 like domain protein; KEGG: oan:Oant_0280 NMT1/THI5 like domain protein; NMT1/THI5 like domain-containing protein 2959228 8326815 Amir_2626 Actinosynnema mirum DSM 43827 NMT1/THI5 like domain-containing protein YP_003100407.1 2958083 R 446462 CDS YP_003100408.1 256376748 8326816 complement(2959399..2960265) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbr:BB0643 transport system permease protein; ABC transporter inner membrane protein 2960265 8326816 Amir_2627 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100408.1 2959399 R 446462 CDS YP_003100409.1 256376749 8326817 complement(2960280..2961107) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pla:Plav_0892 ABC transporter; ABC transporter 2961107 8326817 Amir_2628 Actinosynnema mirum DSM 43827 ABC transporter YP_003100409.1 2960280 R 446462 CDS YP_003100410.1 256376750 8326818 complement(2961293..2961730) 1 NC_013093.1 hypothetical protein 2961730 8326818 Amir_2629 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100410.1 2961293 R 446462 CDS YP_003100411.1 256376751 8326819 complement(2962075..2962677) 1 NC_013093.1 KEGG: bch:Bcen2424_2530 hypothetical protein; hypothetical protein 2962677 8326819 Amir_2630 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100411.1 2962075 R 446462 CDS YP_003100412.1 256376752 8326820 complement(2962674..2964263) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RS02380 two-component sensor histidine kinase transcription regulator protein; histidine kinase 2964263 8326820 Amir_2631 Actinosynnema mirum DSM 43827 histidine kinase YP_003100412.1 2962674 R 446462 CDS YP_003100413.1 256376753 8326821 complement(2964260..2964949) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfu:Sfum_2007 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 2964949 8326821 Amir_2632 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003100413.1 2964260 R 446462 CDS YP_003100414.1 256376754 8326822 2965420..2966697 1 NC_013093.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: sal:Sala_3102 hypothetical protein; hypothetical protein 2966697 8326822 Amir_2633 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100414.1 2965420 D 446462 CDS YP_003100415.1 256376755 8326823 2966794..2967015 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2967015 8326823 Amir_2634 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100415.1 2966794 D 446462 CDS YP_003100416.1 256376756 8326824 complement(2967074..2968042) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: pla:Plav_2411 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 2968042 8326824 Amir_2635 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003100416.1 2967074 R 446462 CDS YP_003100417.1 256376757 8326825 2968561..2969349 1 NC_013093.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: mno:Mnod_4658 molybdopterin dehydrogenase FAD- binding; FAD-binding molybdopterin dehydrogenase 2969349 8326825 Amir_2636 Actinosynnema mirum DSM 43827 FAD-binding molybdopterin dehydrogenase YP_003100417.1 2968561 D 446462 CDS YP_003100418.1 256376758 8326826 2969349..2972042 1 NC_013093.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: azc:AZC_4623 dehydrogenase; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 2972042 8326826 Amir_2637 Actinosynnema mirum DSM 43827 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_003100418.1 2969349 D 446462 CDS YP_003100419.1 256376759 8326827 complement(2972032..2973465) 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: scl:sce3282 monooxygenase flavin-binding family protein; FAD dependent oxidoreductase 2973465 8326827 Amir_2638 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003100419.1 2972032 R 446462 CDS YP_003100420.1 256376760 8326828 2973644..2974234 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: lch:Lcho_1914 TetR family transcriptional regulator; TetR family transcriptional regulator 2974234 8326828 Amir_2639 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100420.1 2973644 D 446462 CDS YP_003100421.1 256376761 8326829 complement(2974574..2975272) 1 NC_013093.1 hypothetical protein 2975272 8326829 Amir_2640 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100421.1 2974574 R 446462 CDS YP_003100422.1 256376762 8326830 complement(2975269..2975823) 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: lch:Lcho_0031 hypothetical protein; hypothetical protein 2975823 8326830 Amir_2641 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100422.1 2975269 R 446462 CDS YP_003100423.1 256376763 8326831 complement(2975820..2976317) 1 NC_013093.1 hypothetical protein 2976317 8326831 Amir_2642 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100423.1 2975820 R 446462 CDS YP_003100424.1 256376764 8326832 complement(2976381..2977709) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2977709 8326832 Amir_2643 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100424.1 2976381 R 446462 CDS YP_003100425.1 256376765 8326833 complement(2977706..2978206) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 2978206 8326833 Amir_2644 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100425.1 2977706 R 446462 CDS YP_003100426.1 256376766 8326834 complement(2978443..2979207) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pol:Bpro_0095 transcriptional regulator NanR; GntR family transcriptional regulator 2979207 8326834 Amir_2645 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003100426.1 2978443 R 446462 CDS YP_003100427.1 256376767 8326835 2979418..2980779 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0865 transport protein; major facilitator superfamily protein 2980779 8326835 Amir_2646 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100427.1 2979418 D 446462 CDS YP_003100428.1 256376768 8326836 2980776..2982479 1 NC_013093.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone; dihydroxyacetone kinase 2982479 8326836 Amir_2647 Actinosynnema mirum DSM 43827 dihydroxyacetone kinase YP_003100428.1 2980776 D 446462 CDS YP_003100429.1 256376769 8326837 2982534..2983016 1 NC_013093.1 TIGRFAM: ribose 5-phosphate isomerase; sugar- phosphate isomerase, RpiB/LacA/LacB family; PFAM: ribose/galactose isomerase; KEGG: similar to ribose 5-phosphate isomerase; K01808 ribose 5-phosphate isomerase B; ribose 5-phosphate isomerase 2983016 8326837 Amir_2648 Actinosynnema mirum DSM 43827 ribose 5-phosphate isomerase YP_003100429.1 2982534 D 446462 CDS YP_003100430.1 256376770 8326838 2983016..2983789 1 NC_013093.1 PFAM: triosephosphate isomerase; KEGG: eca:ECA0867 triosephosphate isomerase; triose-phosphate isomerase 2983789 8326838 Amir_2649 Actinosynnema mirum DSM 43827 triose-phosphate isomerase YP_003100430.1 2983016 D 446462 CDS YP_003100431.1 256376771 8326839 2983786..2984586 1 NC_013093.1 PFAM: xylose isomerase; KEGG: eca:ECA0868 hypothetical protein; xylose isomerase 2984586 8326839 Amir_2650 Actinosynnema mirum DSM 43827 xylose isomerase YP_003100431.1 2983786 D 446462 CDS YP_003100432.1 256376772 8326840 2984583..2985437 1 NC_013093.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Acetohydroxy acid isomeroreductase catalytic domain protein; KEGG: eca:ECA0869 hypothetical protein; NADP oxidoreductase coenzyme F420-dependent 2985437 8326840 Amir_2651 Actinosynnema mirum DSM 43827 NADP oxidoreductase coenzyme F420-dependent YP_003100432.1 2984583 D 446462 CDS YP_003100433.1 256376773 8326841 2986179..2986871 1 NC_013093.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: scl:sce0560 hypothetical protein; CRISPR-associated protein, Cse3 family 2986871 8326841 Amir_2652 Actinosynnema mirum DSM 43827 CRISPR-associated protein, Cse3 family YP_003100433.1 2986179 D 446462 CDS YP_003100434.1 256376774 8326842 complement(2988003..2988200) 1 NC_013093.1 hypothetical protein 2988200 8326842 Amir_2653 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100434.1 2988003 R 446462 CDS YP_003100435.1 256376775 8326843 2988393..2988938 1 NC_013093.1 KEGG: gbe:GbCGDNIH1_0912 phosphate transport system permease protein PstA; hypothetical protein 2988938 8326843 Amir_2654 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100435.1 2988393 D 446462 CDS YP_003100436.1 256376776 8326844 2988961..2989506 1 NC_013093.1 KEGG: scl:sce2943 phosphate ABC transporter, ATP- binding protein PstB; phosphate ABC transporter ATP-binding protein PstB 2989506 8326844 Amir_2655 Actinosynnema mirum DSM 43827 phosphate ABC transporter ATP-binding protein PstB YP_003100436.1 2988961 D 446462 CDS YP_003100437.1 256376777 8326845 complement(2989650..2990159) 1 NC_013093.1 KEGG: yen:YE4124 isochorismatase family hydrolase; hypothetical protein 2990159 8326845 Amir_2656 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100437.1 2989650 R 446462 CDS YP_003100438.1 256376778 8326846 2990251..2990916 1 NC_013093.1 hypothetical protein 2990916 8326846 Amir_2657 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100438.1 2990251 D 446462 CDS YP_003100439.1 256376779 8326847 2991381..2992367 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: azo:azo0209 sarcosine oxidase, beta subunit; FAD dependent oxidoreductase 2992367 8326847 Amir_2658 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003100439.1 2991381 D 446462 CDS YP_003100440.1 256376780 8326848 2992840..2993079 1 NC_013093.1 KEGG: bha:BH1846 acyl-carrier protein; acyl-carrier protein 2993079 8326848 Amir_2659 Actinosynnema mirum DSM 43827 acyl-carrier protein YP_003100440.1 2992840 D 446462 CDS YP_003100441.1 256376781 8326849 2993188..2994534 1 NC_013093.1 KEGG: bmv:BMASAVP1_A1623 L-ornithine 5- monooxygenase; L-lysine 6-monooxygenase (NADPH) 2994534 8326849 Amir_2660 Actinosynnema mirum DSM 43827 L-lysine 6-monooxygenase (NADPH) YP_003100441.1 2993188 D 446462 CDS YP_003100442.1 256376782 8326850 2994572..2994940 1 NC_013093.1 PFAM: cupin; KEGG: psp:PSPPH_2411 hypothetical protein; cupin 2994940 8326850 Amir_2661 Actinosynnema mirum DSM 43827 cupin YP_003100442.1 2994572 D 446462 CDS YP_003100443.1 256376783 8326851 2994937..2996565 1 NC_013093.1 PFAM: tRNA synthetase class I (M); KEGG: pen:PSEEN0982 methionine--tRNA ligase; methionine--tRNA ligase 2996565 8326851 Amir_2662 Actinosynnema mirum DSM 43827 methionine--tRNA ligase YP_003100443.1 2994937 D 446462 CDS YP_003100444.1 256376784 8326852 2996575..2997816 1 NC_013093.1 PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylglycinamide synthetase; KEGG: plu:plu0116 hypothetical protein; ATP-dependent carboxylate-amine ligase domain-containing protein 2997816 8326852 Amir_2663 Actinosynnema mirum DSM 43827 ATP-dependent carboxylate-amine ligase domain-containing protein YP_003100444.1 2996575 D 446462 CDS YP_003100445.1 256376785 8326853 2997919..2998740 1 NC_013093.1 PFAM: amidinotransferase; KEGG: aeh:Mlg_0130 amidinotransferase; amidinotransferase 2998740 8326853 Amir_2664 Actinosynnema mirum DSM 43827 amidinotransferase YP_003100445.1 2997919 D 446462 CDS YP_003100446.1 256376786 8326854 2998737..2999099 1 NC_013093.1 KEGG: gbm:Gbem_0509 hypothetical protein; hypothetical protein 2999099 8326854 Amir_2665 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100446.1 2998737 D 446462 CDS YP_003100447.1 256376787 8326855 2999243..3001096 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: acr:Acry_1185 extracellular solute-binding protein; family 5 extracellular solute-binding protein 3001096 8326855 Amir_2666 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003100447.1 2999243 D 446462 CDS YP_003100448.1 256376788 8326856 3001093..3002400 1 NC_013093.1 PFAM: sodium/hydrogen exchanger; KEGG: mno:Mnod_3112 sodium/hydrogen exchanger; sodium/hydrogen exchanger 3002400 8326856 Amir_2667 Actinosynnema mirum DSM 43827 sodium/hydrogen exchanger YP_003100448.1 3001093 D 446462 CDS YP_003100449.1 256376789 8326857 3002520..3003767 1 NC_013093.1 PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: plu:plu0116 hypothetical protein; phosphoribosylglycinamide synthetase 3003767 8326857 Amir_2668 Actinosynnema mirum DSM 43827 phosphoribosylglycinamide synthetase YP_003100449.1 3002520 D 446462 CDS YP_003100450.1 256376790 8326858 3003888..3005195 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: ank:AnaeK_4388 major facilitator superfamily MFS_1; major facilitator superfamily protein 3005195 8326858 Amir_2669 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100450.1 3003888 D 446462 CDS YP_003100451.1 256376791 8326859 3005322..3005822 1 NC_013093.1 hypothetical protein 3005822 8326859 Amir_2670 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100451.1 3005322 D 446462 CDS YP_003100452.1 256376792 8326860 3006523..3008538 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: mxa:MXAN_2296 O-methyltransferase family protein; O-methyltransferase 3008538 8326860 Amir_2671 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003100452.1 3006523 D 446462 CDS YP_003100453.1 256376793 8326861 complement(join(3008596..3009096,3009098..3009199)) 1 NC_013093.1 KEGG: ade:Adeh_0244 LigA; LigA 3009199 8326861 Amir_2672 Actinosynnema mirum DSM 43827 LigA YP_003100453.1 3008596 R 446462 CDS YP_003100454.1 256376794 8326862 3009401..3012139 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3012139 8326862 Amir_2673 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100454.1 3009401 D 446462 CDS YP_003100455.1 256376795 8326863 3012438..3013211 1 NC_013093.1 KEGG: hch:HCH_01940 phytoene dehydrogenase and related protein; hypothetical protein 3013211 8326863 Amir_2674 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100455.1 3012438 D 446462 CDS YP_003100456.1 256376796 8326864 join(3013345..3015780,3015780..3015956) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; hypothetical protein 3015956 8326864 Amir_2675 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100456.1 3013345 D 446462 CDS YP_003100457.1 256376797 8326865 3016403..3017134 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bca:BCE_2589 ATP-binding transport protein NatA; ABC transporter 3017134 8326865 Amir_2676 Actinosynnema mirum DSM 43827 ABC transporter YP_003100457.1 3016403 D 446462 CDS YP_003100458.1 256376798 8326866 3017170..3017430 1 NC_013093.1 hypothetical protein 3017430 8326866 Amir_2677 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100458.1 3017170 D 446462 CDS YP_003100459.1 256376799 8326867 complement(3017571..3018395) 1 NC_013093.1 PFAM: Thioesterase; KEGG: bpd:BURPS668_A0873 pyochelin biosynthetic protein PchC; oleoyl-(acyl-carrier-protein) hydrolase 3018395 8326867 Amir_2678 Actinosynnema mirum DSM 43827 oleoyl-(acyl-carrier-protein) hydrolase YP_003100459.1 3017571 R 446462 CDS YP_003100460.1 256376800 8326868 complement(3018623..3019255) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: tmz:Tmz1t_0804 transcriptional regulator, TetR family; TetR family transcriptional regulator 3019255 8326868 Amir_2679 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100460.1 3018623 R 446462 CDS YP_003100461.1 256376801 8326869 3019338..3021143 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_1369 major facilitator superfamily MFS_1; major facilitator superfamily protein 3021143 8326869 Amir_2680 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100461.1 3019338 D 446462 CDS YP_003100462.1 256376802 8326870 3021545..3026995 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; KR domain protein; acyl transferase; erythronolide synthase docking; phosphopantetheine- binding; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA0602 type I polyketide synthase; short-chain dehydrogenase/reductase SDR 3026995 8326870 Amir_2681 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100462.1 3021545 D 446462 CDS YP_003100463.1 256376803 8326871 3027042..3036320 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; acyl transferase; KR domain protein; erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; short-chain dehydrogenase/reductase SDR 3036320 8326871 Amir_2682 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100463.1 3027042 D 446462 CDS YP_003100464.1 256376804 8326872 3036332..3041137 1 NC_013093.1 PFAM: acyl transferase; beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 3041137 8326872 Amir_2683 Actinosynnema mirum DSM 43827 acyl transferase YP_003100464.1 3036332 D 446462 CDS YP_003100465.1 256376805 8326873 3041176..3057378 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; acyl transferase; KR domain protein; erythronolide synthase docking; Thioesterase; NAD- dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: met:M446_0170 beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR 3057378 8326873 Amir_2684 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100465.1 3041176 D 446462 CDS YP_003100466.1 256376806 8326874 3057462..3058352 1 NC_013093.1 TIGRFAM: proline-specific peptidase; PFAM: alpha/beta hydrolase fold; KEGG: rru:Rru_A2180 peptidase S33, tricorn interacting factor 1; proline-specific peptidase 3058352 8326874 Amir_2685 Actinosynnema mirum DSM 43827 proline-specific peptidase YP_003100466.1 3057462 D 446462 CDS YP_003100467.1 256376807 8326875 complement(3058366..3058851) 1 NC_013093.1 hypothetical protein 3058851 8326875 Amir_2686 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100467.1 3058366 R 446462 CDS YP_003100468.1 256376808 8326876 complement(3059008..3059256) 1 NC_013093.1 KEGG: mrd:Mrad2831_0184 phosphopantetheine-binding; phosphopantetheine-binding 3059256 8326876 Amir_2687 Actinosynnema mirum DSM 43827 phosphopantetheine-binding YP_003100468.1 3059008 R 446462 CDS YP_003100469.1 256376809 8326877 3059475..3061064 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: gbm:Gbem_0542 amino acid adenylation domain protein; AMP-dependent synthetase and ligase 3061064 8326877 Amir_2688 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003100469.1 3059475 D 446462 CDS YP_003100470.1 256376810 8326878 complement(3061179..3062702) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_0131 amino acid adenylation domain- containing protein; AMP-dependent synthetase and ligase 3062702 8326878 Amir_2689 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003100470.1 3061179 R 446462 CDS YP_003100471.1 256376811 8326879 complement(3062743..3063669) 1 NC_013093.1 KEGG: plu:plu2834 acyl carrier protein S- malonyltransferase; (acyl-carrier-protein)S-malonyltransferase-like protein 3063669 8326879 Amir_2690 Actinosynnema mirum DSM 43827 (acyl-carrier-protein)S-malonyltransferase-like protein YP_003100471.1 3062743 R 446462 CDS YP_003100472.1 256376812 8326880 complement(3063696..3064955) 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase; class I and II aminotransferase 3064955 8326880 Amir_2691 Actinosynnema mirum DSM 43827 class I and II aminotransferase YP_003100472.1 3063696 R 446462 CDS YP_003100473.1 256376813 8326881 complement(3065051..3066403) 1 NC_013093.1 KEGG: mxa:MXAN_6263 hypothetical protein; L-lysine 2,3-aminomutase 3066403 8326881 Amir_2692 Actinosynnema mirum DSM 43827 L-lysine 2,3-aminomutase YP_003100473.1 3065051 R 446462 CDS YP_003100474.1 256376814 8326882 3066961..3068148 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bca:BCE_2696 cytochrome P450; cytochrome P450 3068148 8326882 Amir_2693 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100474.1 3066961 D 446462 CDS YP_003100475.1 256376815 8326883 3068145..3068387 1 NC_013093.1 KEGG: cak:Caul_1918 hypothetical protein; hypothetical protein 3068387 8326883 Amir_2694 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100475.1 3068145 D 446462 CDS YP_003100476.1 256376816 8326884 3068486..3089818 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; Male sterility domain; acyl transferase; KR domain protein; phosphopantetheine- binding; NAD-dependent epimerase/dehydratase; KEGG: met:M446_0170 beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR 3089818 8326884 Amir_2695 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100476.1 3068486 D 446462 CDS YP_003100477.1 256376817 8326885 3090196..3092991 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: reh:H16_A1278 ATP-dependent transcriptional regulator containing adenylate cyclase related domains; LuxR family transcriptional regulator 3092991 8326885 Amir_2696 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100477.1 3090196 D 446462 CDS YP_003100478.1 256376818 8326886 3093198..3094037 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: glo:Glov_3629 ABC transporter; ABC transporter 3094037 8326886 Amir_2697 Actinosynnema mirum DSM 43827 ABC transporter YP_003100478.1 3093198 D 446462 CDS YP_003100479.1 256376819 8326887 3094037..3096604 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: gme:Gmet_1517 hypothetical protein; hypothetical protein 3096604 8326887 Amir_2698 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100479.1 3094037 D 446462 CDS YP_003100480.1 256376820 8326888 complement(3097146..3097826) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: psb:Psyr_1940 LuxR response regulator receiver; LuxR family transcriptional regulator 3097826 8326888 Amir_2699 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100480.1 3097146 R 446462 CDS YP_003100481.1 256376821 8326889 complement(3097790..3099079) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: cps:CPS_1261 sensor histidine kinase; histidine kinase 3099079 8326889 Amir_2700 Actinosynnema mirum DSM 43827 histidine kinase YP_003100481.1 3097790 R 446462 CDS YP_003100482.1 256376822 8326890 3099293..3100354 1 NC_013093.1 hypothetical protein 3100354 8326890 Amir_2701 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100482.1 3099293 D 446462 CDS YP_003100483.1 256376823 8326891 3100521..3101567 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3101567 8326891 Amir_2702 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100483.1 3100521 D 446462 CDS YP_003100484.1 256376824 8326892 3101661..3103421 1 NC_013093.1 PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; Cna B domain-containing protein 3103421 8326892 Amir_2703 Actinosynnema mirum DSM 43827 Cna B domain-containing protein YP_003100484.1 3101661 D 446462 CDS YP_003100485.1 256376825 8326893 complement(3103431..3103922) 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: mlo:mlr0279 O-methyltransferase; O-methyltransferase 3103922 8326893 Amir_2704 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003100485.1 3103431 R 446462 CDS YP_003100486.1 256376826 8326894 complement(3103926..3105230) 1 NC_013093.1 KEGG: afw:Anae109_2424 DNA mismatch repair protein MutS domain-containing protein; hypothetical protein 3105230 8326894 Amir_2705 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100486.1 3103926 R 446462 CDS YP_003100487.1 256376827 8326895 3105498..3106568 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: rle:RL3052 cationic solute-binding component of ABC transporter; periplasmic binding protein 3106568 8326895 Amir_2706 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003100487.1 3105498 D 446462 CDS YP_003100488.1 256376828 8326896 3106565..3107587 1 NC_013093.1 PFAM: transport system permease protein; ABC transporter; KEGG: rec:RHECIAT_PC0000463 iron ABC transporter, permease protein; transport system permease 3107587 8326896 Amir_2707 Actinosynnema mirum DSM 43827 transport system permease YP_003100488.1 3106565 D 446462 CDS YP_003100489.1 256376829 8326897 3107584..3108357 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mpo:Mpop_4222 ABC transporter; ABC transporter 3108357 8326897 Amir_2708 Actinosynnema mirum DSM 43827 ABC transporter YP_003100489.1 3107584 D 446462 CDS YP_003100490.1 256376830 8326898 complement(3108506..3109084) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bcr:BCAH187_A5151 transcriptional regulator, TetR family; TetR family transcriptional regulator 3109084 8326898 Amir_2709 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100490.1 3108506 R 446462 CDS YP_003100491.1 256376831 8326899 3109179..3109892 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: Zn-dependent hydrolases, including glyoxylases; beta-lactamase domain-containing protein 3109892 8326899 Amir_2710 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003100491.1 3109179 D 446462 CDS YP_003100492.1 256376832 8326900 3110003..3110284 1 NC_013093.1 KEGG: sal:Sala_0018 hypothetical protein; hypothetical protein 3110284 8326900 Amir_2711 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100492.1 3110003 D 446462 CDS YP_003100493.1 256376833 8326901 complement(3110281..3110814) 1 NC_013093.1 KEGG: jan:Jann_1769 mucin-associated surface protein; mucin-associated surface protein 3110814 8326901 Amir_2712 Actinosynnema mirum DSM 43827 mucin-associated surface protein YP_003100493.1 3110281 R 446462 CDS YP_003100494.1 256376834 8326902 complement(3110811..3113327) 1 NC_013093.1 PFAM: NB-ARC domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; NB-ARC domain-containing protein 3113327 8326902 Amir_2713 Actinosynnema mirum DSM 43827 NB-ARC domain-containing protein YP_003100494.1 3110811 R 446462 CDS YP_003100495.1 256376835 8326903 complement(3113324..3113875) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mxa:MXAN_2145 transcriptional regulator, TetR family; TetR family transcriptional regulator 3113875 8326903 Amir_2714 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100495.1 3113324 R 446462 CDS YP_003100496.1 256376836 8326904 3113968..3114873 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4431 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin; luciferase-like monooxygenase 3114873 8326904 Amir_2715 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100496.1 3113968 D 446462 CDS YP_003100497.1 256376837 8326905 complement(3114940..3117765) 1 NC_013093.1 PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; LuxR family transcriptional regulator 3117765 8326905 Amir_2716 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100497.1 3114940 R 446462 CDS YP_003100498.1 256376838 8326906 complement(3118394..3119455) 1 NC_013093.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 3119455 8326906 Amir_2717 Actinosynnema mirum DSM 43827 phospho-2-dehydro-3-deoxyheptonate aldolase YP_003100498.1 3118394 R 446462 CDS YP_003100499.1 256376839 8326907 complement(3119448..3120851) 1 NC_013093.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: gdj:Gdia_2404 drug resistance transporter, EmrB/QacA subfamily; EmrB/QacA subfamily drug resistance transporter 3120851 8326907 Amir_2718 Actinosynnema mirum DSM 43827 EmrB/QacA subfamily drug resistance transporter YP_003100499.1 3119448 R 446462 CDS YP_003100500.1 256376840 8326908 complement(3120848..3131080) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; non- ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: pap:PSPA7_2858 peptide synthase; amino acid adenylation domain-containing protein 3131080 8326908 Amir_2719 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003100500.1 3120848 R 446462 CDS YP_003100501.1 256376841 8326909 complement(3131153..3131938) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: dac:Daci_3149 ABC transporter; ABC transporter 3131938 8326909 Amir_2720 Actinosynnema mirum DSM 43827 ABC transporter YP_003100501.1 3131153 R 446462 CDS YP_003100502.1 256376842 8326910 complement(3131935..3132951) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: yen:YE3620 iron-enterobactin transporter permease; transport system permease 3132951 8326910 Amir_2721 Actinosynnema mirum DSM 43827 transport system permease YP_003100502.1 3131935 R 446462 CDS YP_003100503.1 256376843 8326911 complement(3132948..3133946) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: cvi:CV_2236 iron-enterobactin transporter membrane protein; transport system permease 3133946 8326911 Amir_2722 Actinosynnema mirum DSM 43827 transport system permease YP_003100503.1 3132948 R 446462 CDS YP_003100504.1 256376844 8326912 complement(3133943..3134965) 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: bsu:BSU39610 hypothetical protein; periplasmic binding protein 3134965 8326912 Amir_2723 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003100504.1 3133943 R 446462 CDS YP_003100505.1 256376845 8326913 complement(3135012..3135947) 1 NC_013093.1 PFAM: siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: cti:RALTA_B1102 siderophore-interacting protein; siderophore-interacting protein 3135947 8326913 Amir_2724 Actinosynnema mirum DSM 43827 siderophore-interacting protein YP_003100505.1 3135012 R 446462 CDS YP_003100506.1 256376846 8326915 complement(3136848..3138524) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce3880 (2,3-dihydroxybenzoyl)adenylate synthase; AMP-dependent synthetase and ligase 3138524 8326915 Amir_2726 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003100506.1 3136848 R 446462 CDS YP_003100507.1 256376847 8326916 complement(3138521..3140032) 1 NC_013093.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: mxa:MXAN_3646 isochorismate synthase DhbC; isochorismate synthase 3140032 8326916 Amir_2727 Actinosynnema mirum DSM 43827 isochorismate synthase YP_003100507.1 3138521 R 446462 CDS YP_003100508.1 256376848 8326917 complement(3140270..3141040) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bcy:Bcer98_1754 2,3-dihydroxybenzoate-2,3- dehydrogenase; short-chain dehydrogenase/reductase SDR 3141040 8326917 Amir_2728 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100508.1 3140270 R 446462 CDS YP_003100509.1 256376849 8326918 complement(3141299..3142846) 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: hypothetical protein; TAP domain-containing protein 3142846 8326918 Amir_2729 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003100509.1 3141299 R 446462 CDS YP_003100510.1 256376850 8326919 3143249..3144301 1 NC_013093.1 PFAM: transport system permease protein; KEGG: dac:Daci_3791 transport system permease protein; transport system permease 3144301 8326919 Amir_2730 Actinosynnema mirum DSM 43827 transport system permease YP_003100510.1 3143249 D 446462 CDS YP_003100511.1 256376851 8326920 3144301..3145068 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bte:BTH_I1413 iron compound ABC transporter, ATP-binding protein; ABC transporter 3145068 8326920 Amir_2731 Actinosynnema mirum DSM 43827 ABC transporter YP_003100511.1 3144301 D 446462 CDS YP_003100512.1 256376852 8326921 3145138..3146154 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: bpd:BURPS668_3152 iron chelate uptake ABC transporter, periplasmic solute-binding protein; periplasmic binding protein 3146154 8326921 Amir_2732 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003100512.1 3145138 D 446462 CDS YP_003100513.1 256376853 8326922 complement(3146360..3146572) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: bcr:BCAH187_A3038 DNA-binding protein; XRE family transcriptional regulator 3146572 8326922 Amir_2733 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100513.1 3146360 R 446462 CDS YP_003100514.1 256376854 8326923 complement(3146574..3147053) 1 NC_013093.1 hypothetical protein 3147053 8326923 Amir_2734 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100514.1 3146574 R 446462 CDS YP_003100515.1 256376855 8326924 complement(3147165..3147662) 1 NC_013093.1 KEGG: bpl:BURPS1106A_1193 DNA translocase FtsK; hypothetical protein 3147662 8326924 Amir_2735 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100515.1 3147165 R 446462 CDS YP_003100516.1 256376856 8326925 3147876..3149168 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3149168 8326925 Amir_2736 Actinosynnema mirum DSM 43827 histidine kinase YP_003100516.1 3147876 D 446462 CDS YP_003100517.1 256376857 8326926 3149165..3149848 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 3149848 8326926 Amir_2737 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100517.1 3149165 D 446462 CDS YP_003100518.1 256376858 8326928 3153038..3154318 1 NC_013093.1 KEGG: azc:AZC_3061 enolase; TIGRFAM: enolase; PFAM: enolase; enolase 3154318 8326928 Amir_2739 Actinosynnema mirum DSM 43827 enolase YP_003100518.1 3153038 D 446462 CDS YP_003100519.1 256376859 8326929 complement(3154305..3154508) 1 NC_013093.1 hypothetical protein 3154508 8326929 Amir_2740 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100519.1 3154305 R 446462 CDS YP_003100520.1 256376860 8326930 complement(3154505..3155335) 1 NC_013093.1 hypothetical protein 3155335 8326930 Amir_2741 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100520.1 3154505 R 446462 CDS YP_003100521.1 256376861 8326931 3155761..3156639 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bsu:BSU09890 hypothetical protein; ABC transporter 3156639 8326931 Amir_2742 Actinosynnema mirum DSM 43827 ABC transporter YP_003100521.1 3155761 D 446462 CDS YP_003100522.1 256376862 8326932 3156639..3157721 1 NC_013093.1 KEGG: bha:BH1167 hypothetical protein; sodium ABC transporter permease 3157721 8326932 Amir_2743 Actinosynnema mirum DSM 43827 sodium ABC transporter permease YP_003100522.1 3156639 D 446462 CDS YP_003100523.1 256376863 8326933 3157897..3159756 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3159756 8326933 Amir_2744 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100523.1 3157897 D 446462 CDS YP_003100524.1 256376864 8326934 complement(3159898..3161466) 1 NC_013093.1 PFAM: chemotaxis sensory transducer; GAF domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer with GAF sensor 3161466 8326934 Amir_2745 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer with GAF sensor YP_003100524.1 3159898 R 446462 CDS YP_003100525.1 256376865 8326935 3161696..3162205 1 NC_013093.1 PFAM: GAF domain protein; KEGG: tmz:Tmz1t_1845 multi-sensor hybrid histidine kinase; GAF sensor protein 3162205 8326935 Amir_2746 Actinosynnema mirum DSM 43827 GAF sensor protein YP_003100525.1 3161696 D 446462 CDS YP_003100526.1 256376866 8326936 3162460..3163110 1 NC_013093.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: gbm:Gbem_1372 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 3163110 8326936 Amir_2747 Actinosynnema mirum DSM 43827 ErfK/YbiS/YcfS/YnhG family protein YP_003100526.1 3162460 D 446462 CDS YP_003100527.1 256376867 8326937 3163267..3163428 1 NC_013093.1 hypothetical protein 3163428 8326937 Amir_2748 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100527.1 3163267 D 446462 CDS YP_003100528.1 256376868 8326938 3163684..3163986 1 NC_013093.1 hypothetical protein 3163986 8326938 Amir_2749 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100528.1 3163684 D 446462 CDS YP_003100529.1 256376869 8326939 3164541..3171884 1 NC_013093.1 KEGG: bcb:BCB4264_A3445 wall-associated protein; TIGRFAM: YD repeat protein; PFAM: PA14 domain protein; YD repeat-containing protein; SMART: PA14 domain protein; LamG domain protein jellyroll fold domain protein; YD repeat-containing protein 3171884 8326939 Amir_2750 Actinosynnema mirum DSM 43827 YD repeat-containing protein YP_003100529.1 3164541 D 446462 CDS YP_003100530.1 256376870 8326940 3171962..3172429 1 NC_013093.1 hypothetical protein 3172429 8326940 Amir_2751 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100530.1 3171962 D 446462 CDS YP_003100531.1 256376871 8326941 complement(3172442..3172726) 1 NC_013093.1 hypothetical protein 3172726 8326941 Amir_2752 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100531.1 3172442 R 446462 CDS YP_003100532.1 256376872 8326942 complement(3172827..3173732) 1 NC_013093.1 PFAM: sugar isomerase (SIS); KEGG: rso:RSc1377 hypothetical protein; RpiR family transcriptional regulator 3173732 8326942 Amir_2753 Actinosynnema mirum DSM 43827 RpiR family transcriptional regulator YP_003100532.1 3172827 R 446462 CDS YP_003100533.1 256376873 8326943 3173871..3175268 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: bpy:Bphyt_2088 major facilitator superfamily MFS_1; major facilitator superfamily protein 3175268 8326943 Amir_2754 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100533.1 3173871 D 446462 CDS YP_003100534.1 256376874 8326944 3175265..3175699 1 NC_013093.1 KEGG: vei:Veis_0546 GAF sensor protein; GAF sensor protein 3175699 8326944 Amir_2755 Actinosynnema mirum DSM 43827 GAF sensor protein YP_003100534.1 3175265 D 446462 CDS YP_003100535.1 256376875 8326945 3175696..3176907 1 NC_013093.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: rru:Rru_A3412 amidohydrolase; amidohydrolase 3176907 8326945 Amir_2756 Actinosynnema mirum DSM 43827 amidohydrolase YP_003100535.1 3175696 D 446462 CDS YP_003100536.1 256376876 8326946 complement(3176968..3177612) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; response regulator receiver; KEGG: bxe:Bxe_A1815 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 3177612 8326946 Amir_2757 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100536.1 3176968 R 446462 CDS YP_003100537.1 256376877 8326947 complement(3177600..3178769) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: mch:Mchl_4713 histidine kinase; histidine kinase 3178769 8326947 Amir_2758 Actinosynnema mirum DSM 43827 histidine kinase YP_003100537.1 3177600 R 446462 CDS YP_003100538.1 256376878 8326948 3178855..3179625 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pla:Plav_1100 ABC transporter; ABC transporter 3179625 8326948 Amir_2759 Actinosynnema mirum DSM 43827 ABC transporter YP_003100538.1 3178855 D 446462 CDS YP_003100539.1 256376879 8326949 3179625..3182093 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: mxa:MXAN_6766 ABC transporter, permease protein; hypothetical protein 3182093 8326949 Amir_2760 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100539.1 3179625 D 446462 CDS YP_003100540.1 256376880 8326950 3182217..3182645 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 3182645 8326950 Amir_2761 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003100540.1 3182217 D 446462 CDS YP_003100541.1 256376881 8326951 3183189..3183293 1 NC_013093.1 hypothetical protein 3183293 8326951 Amir_2762 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100541.1 3183189 D 446462 CDS YP_003100542.1 256376882 8326952 3183375..3184583 1 NC_013093.1 KEGG: sdn:Sden_2265 hypothetical protein; hypothetical protein 3184583 8326952 Amir_2763 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100542.1 3183375 D 446462 CDS YP_003100543.1 256376883 8326953 3184580..3186631 1 NC_013093.1 PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: sdn:Sden_2266 hypothetical protein; hypothetical protein 3186631 8326953 Amir_2764 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100543.1 3184580 D 446462 CDS YP_003100544.1 256376884 8326954 3187367..3188599 1 NC_013093.1 PFAM: ROK family protein; KEGG: mxa:MXAN_6549 transcriptional regulator, ROK family; ROK family protein 3188599 8326954 Amir_2765 Actinosynnema mirum DSM 43827 ROK family protein YP_003100544.1 3187367 D 446462 CDS YP_003100545.1 256376885 8326955 3188784..3190451 1 NC_013093.1 hypothetical protein 3190451 8326955 Amir_2766 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100545.1 3188784 D 446462 CDS YP_003100546.1 256376886 8326956 complement(3190466..3192613) 1 NC_013093.1 KEGG: scl:sce5225 protein kinase; hypothetical protein 3192613 8326956 Amir_2767 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100546.1 3190466 R 446462 CDS YP_003100547.1 256376887 8326957 complement(3192907..3193557) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3193557 8326957 Amir_2768 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100547.1 3192907 R 446462 CDS YP_003100548.1 256376888 8326958 complement(3193712..3195931) 1 NC_013093.1 TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: mxa:MXAN_3422 copper-translocating P-type ATPase; heavy metal translocating P-type ATPase 3195931 8326958 Amir_2769 Actinosynnema mirum DSM 43827 heavy metal translocating P-type ATPase YP_003100548.1 3193712 R 446462 CDS YP_003100549.1 256376889 8326959 complement(3195993..3197891) 1 NC_013093.1 PFAM: copper resistance D domain protein; KEGG: csa:Csal_0081 hypothetical protein; copper resistance D domain-containing protein 3197891 8326959 Amir_2770 Actinosynnema mirum DSM 43827 copper resistance D domain-containing protein YP_003100549.1 3195993 R 446462 CDS YP_003100550.1 256376890 8326960 3198006..3198737 1 NC_013093.1 PFAM: DSBA oxidoreductase; KEGG: mxa:MXAN_3206 DsbA-like thioredoxin domain protein; DSBA oxidoreductase 3198737 8326960 Amir_2771 Actinosynnema mirum DSM 43827 DSBA oxidoreductase YP_003100550.1 3198006 D 446462 CDS YP_003100551.1 256376891 8326961 3198734..3199279 1 NC_013093.1 PFAM: vitamin K epoxide reductase; SMART: vitamin K epoxide reductase; KEGG: scl:sce9005 hypothetical protein; vitamin K epoxide reductase 3199279 8326961 Amir_2772 Actinosynnema mirum DSM 43827 vitamin K epoxide reductase YP_003100551.1 3198734 D 446462 CDS YP_003100552.1 256376892 8326962 complement(3199384..3199962) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: bid:Bind_3241 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 3199962 8326962 Amir_2773 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003100552.1 3199384 R 446462 CDS YP_003100553.1 256376893 8326963 3200007..3200735 1 NC_013093.1 KEGG: rso:RS02209 transmembrane protein; integral membrane protein 3200735 8326963 Amir_2774 Actinosynnema mirum DSM 43827 integral membrane protein YP_003100553.1 3200007 D 446462 CDS YP_003100554.1 256376894 8326964 3200780..3201331 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bcm:Bcenmc03_1936 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 3201331 8326964 Amir_2775 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003100554.1 3200780 D 446462 CDS YP_003100555.1 256376895 8326965 complement(3201351..3201971) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bha:BH2103 hypothetical protein; TetR family transcriptional regulator 3201971 8326965 Amir_2776 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100555.1 3201351 R 446462 CDS YP_003100556.1 256376896 8326966 3202011..3203837 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: bcb:BCB4264_A1961 ABC transporter, permease/ATP-binding protein; ABC transporter 3203837 8326966 Amir_2777 Actinosynnema mirum DSM 43827 ABC transporter YP_003100556.1 3202011 D 446462 CDS YP_003100557.1 256376897 8326967 3203971..3204924 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4431 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin; luciferase-like monooxygenase 3204924 8326967 Amir_2778 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100557.1 3203971 D 446462 CDS YP_003100558.1 256376898 8326968 3204921..3205478 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mrd:Mrad2831_1768 TetR family transcriptional regulator; TetR family transcriptional regulator 3205478 8326968 Amir_2779 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100558.1 3204921 D 446462 CDS YP_003100559.1 256376899 8326969 3205511..3206698 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpn:KPN_00876 DeoR-type transcriptional regulator; major facilitator superfamily protein 3206698 8326969 Amir_2780 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100559.1 3205511 D 446462 CDS YP_003100560.1 256376900 8326970 3207073..3209118 1 NC_013093.1 PFAM: glycoside hydrolase family 5; protein of unknown function DUF291; cellulose-binding family II; SMART: cellulose-binding family II; KEGG: bha:BH0603 endo-beta-1,4-glucanase (celulase B); glycoside hydrolase family protein 3209118 8326970 Amir_2781 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003100560.1 3207073 D 446462 CDS YP_003100561.1 256376901 8326971 complement(3209260..3210144) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: mxa:MXAN_1575 transcriptional regulator, LysR family; LysR family transcriptional regulator 3210144 8326971 Amir_2782 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003100561.1 3209260 R 446462 CDS YP_003100562.1 256376902 8326972 3210249..3211157 1 NC_013093.1 catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 3211157 8326972 Amir_2783 Actinosynnema mirum DSM 43827 threonine dehydratase YP_003100562.1 3210249 D 446462 CDS YP_003100563.1 256376903 8326973 complement(3211195..3212049) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: rle:RL4049 hypothetical protein; XRE family transcriptional regulator 3212049 8326973 Amir_2784 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100563.1 3211195 R 446462 CDS YP_003100564.1 256376904 8326974 3212175..3213638 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: swi:Swit_1745 aldehyde dehydrogenase (acceptor); aldehyde dehydrogenase 3213638 8326974 Amir_2785 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003100564.1 3212175 D 446462 CDS YP_003100565.1 256376905 8326975 complement(3213693..3213923) 1 NC_013093.1 hypothetical protein 3213923 8326975 Amir_2786 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100565.1 3213693 R 446462 CDS YP_003100566.1 256376906 8326976 3214052..3214627 1 NC_013093.1 hypothetical protein 3214627 8326976 Amir_2787 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100566.1 3214052 D 446462 CDS YP_003100567.1 256376907 8326977 3214818..3215327 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rpc:RPC_1740 RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 3215327 8326977 Amir_2788 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003100567.1 3214818 D 446462 CDS YP_003100568.1 256376908 8326979 complement(3215811..3218000) 1 NC_013093.1 KEGG: bsu:BSU05430 hypothetical protein; hypothetical protein 3218000 8326979 Amir_2790 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100568.1 3215811 R 446462 CDS YP_003100569.1 256376909 8326980 complement(3218032..3218571) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bav:BAV3196 TetR-family trasncriptional regulator; TetR family transcriptional regulator 3218571 8326980 Amir_2791 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100569.1 3218032 R 446462 CDS YP_003100570.1 256376910 8326981 3219015..3219581 1 NC_013093.1 hypothetical protein 3219581 8326981 Amir_2792 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100570.1 3219015 D 446462 CDS YP_003100571.1 256376911 8326982 complement(3219693..3220460) 1 NC_013093.1 PFAM: GAF domain protein; ANTAR domain protein; SMART: GAF domain protein; KEGG: sus:Acid_4463 GAF sensor protein; GAF domain-containing protein 3220460 8326982 Amir_2793 Actinosynnema mirum DSM 43827 GAF domain-containing protein YP_003100571.1 3219693 R 446462 CDS YP_003100572.1 256376912 8326983 3220753..3221253 1 NC_013093.1 PFAM: protein of unknown function DUF322; KEGG: bha:BH2786 hypothetical protein; hypothetical protein 3221253 8326983 Amir_2794 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100572.1 3220753 D 446462 CDS YP_003100573.1 256376913 8326984 3221250..3221855 1 NC_013093.1 KEGG: GH15499 gene product from transcript GH15499- RA; hypothetical protein 3221855 8326984 Amir_2795 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100573.1 3221250 D 446462 CDS YP_003100574.1 256376914 8326985 3221852..3222028 1 NC_013093.1 hypothetical protein 3222028 8326985 Amir_2796 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100574.1 3221852 D 446462 CDS YP_003100575.1 256376915 8326986 3222034..3222447 1 NC_013093.1 PFAM: protein of unknown function DUF322; KEGG: mes:Meso_4196 protein of unknown function DUF1403; hypothetical protein 3222447 8326986 Amir_2797 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100575.1 3222034 D 446462 CDS YP_003100576.1 256376916 8326987 3222444..3222989 1 NC_013093.1 hypothetical protein 3222989 8326987 Amir_2798 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100576.1 3222444 D 446462 CDS YP_003100577.1 256376917 8326988 3222986..3223588 1 NC_013093.1 hypothetical protein 3223588 8326988 Amir_2799 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100577.1 3222986 D 446462 CDS YP_003100578.1 256376918 8326989 3223578..3223868 1 NC_013093.1 hypothetical protein 3223868 8326989 Amir_2800 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100578.1 3223578 D 446462 CDS YP_003100579.1 256376919 8326990 3223865..3224527 1 NC_013093.1 hypothetical protein 3224527 8326990 Amir_2801 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100579.1 3223865 D 446462 CDS YP_003100580.1 256376920 8326992 complement(3226027..3227190) 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: bmn:BMA10247_A2262 glycosyl transferase, group 1 family protein; group 1 glycosyl transferase 3227190 8326992 Amir_2803 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003100580.1 3226027 R 446462 CDS YP_003100581.1 256376921 8326993 complement(3227795..3228592) 1 NC_013093.1 PFAM: GAF domain protein; ANTAR domain protein; SMART: GAF domain protein; KEGG: sus:Acid_4463 GAF sensor protein; GAF domain-containing protein 3228592 8326993 Amir_2804 Actinosynnema mirum DSM 43827 GAF domain-containing protein YP_003100581.1 3227795 R 446462 CDS YP_003100582.1 256376922 8326994 complement(3228634..3229410) 1 NC_013093.1 PFAM: ANTAR domain protein; GAF domain protein; SMART: GAF domain protein; KEGG: azo:azo1490 signaling protein; ANTAR domain-containing protein with unknown sensor 3229410 8326994 Amir_2805 Actinosynnema mirum DSM 43827 ANTAR domain-containing protein with unknown sensor YP_003100582.1 3228634 R 446462 CDS YP_003100583.1 256376923 8326995 complement(3229410..3230129) 1 NC_013093.1 KEGG: afw:Anae109_0792 GAF sensor signal transduction histidine kinase; hypothetical protein 3230129 8326995 Amir_2806 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100583.1 3229410 R 446462 CDS YP_003100584.1 256376924 8326996 complement(3230224..3230691) 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mag:amb0333 anti-anti-sigma regulatory factor; anti-sigma-factor antagonist 3230691 8326996 Amir_2807 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003100584.1 3230224 R 446462 CDS YP_003100585.1 256376925 8326997 3231881..3232513 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3232513 8326997 Amir_2808 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100585.1 3231881 D 446462 CDS YP_003100586.1 256376926 8326998 complement(3232570..3232914) 1 NC_013093.1 hypothetical protein 3232914 8326998 Amir_2809 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100586.1 3232570 R 446462 CDS YP_003100587.1 256376927 8326999 3233060..3236017 1 NC_013093.1 KEGG: GA27442 gene product from transcript GA27442- RA; hypothetical protein 3236017 8326999 Amir_2810 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100587.1 3233060 D 446462 CDS YP_003100588.1 256376928 8327000 complement(3236050..3236703) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; response regulator receiver; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 3236703 8327000 Amir_2811 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100588.1 3236050 R 446462 CDS YP_003100589.1 256376929 8327002 3237954..3239747 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3239747 8327002 Amir_2813 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100589.1 3237954 D 446462 CDS YP_003100590.1 256376930 8327003 3239824..3242874 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3242874 8327003 Amir_2814 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100590.1 3239824 D 446462 CDS YP_003100591.1 256376931 8327004 3243288..3243986 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: sus:Acid_5291 methyltransferase type 11; type 12 methyltransferase 3243986 8327004 Amir_2815 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003100591.1 3243288 D 446462 CDS YP_003100592.1 256376932 8327005 3244342..3245310 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: nwi:Nwi_2406 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 3245310 8327005 Amir_2816 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003100592.1 3244342 D 446462 CDS YP_003100593.1 256376933 8327006 3245310..3246332 1 NC_013093.1 PFAM: Radical SAM domain protein; KEGG: bma:BMAA1862 radical SAM domain-containing protein; Radical SAM domain-containing protein 3246332 8327006 Amir_2817 Actinosynnema mirum DSM 43827 Radical SAM domain-containing protein YP_003100593.1 3245310 D 446462 CDS YP_003100594.1 256376934 8327007 3246335..3247291 1 NC_013093.1 KEGG: smd:Smed_3106 hypothetical protein; hypothetical protein 3247291 8327007 Amir_2818 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100594.1 3246335 D 446462 CDS YP_003100595.1 256376935 8327008 3247288..3248643 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: scl:sce0549 glycogen synthase; group 1 glycosyl transferase 3248643 8327008 Amir_2819 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003100595.1 3247288 D 446462 CDS YP_003100596.1 256376936 8327009 3248640..3249332 1 NC_013093.1 PFAM: LmbE family protein; KEGG: dar:Daro_1249 LmbE-like protein; LmbE family protein 3249332 8327009 Amir_2820 Actinosynnema mirum DSM 43827 LmbE family protein YP_003100596.1 3248640 D 446462 CDS YP_003100597.1 256376937 8327010 3249317..3250315 1 NC_013093.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KR domain protein; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; short- chain dehydrogenase/reductase SDR; KEGG: bcj:BCAM2033 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 3250315 8327010 Amir_2821 Actinosynnema mirum DSM 43827 UDP-glucose 4-epimerase YP_003100597.1 3249317 D 446462 CDS YP_003100598.1 256376938 8327011 3250306..3250977 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: afr:AFE_0621 phosphoglycerate mutase family protein; phosphoglycerate mutase 3250977 8327011 Amir_2822 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003100598.1 3250306 D 446462 CDS YP_003100599.1 256376939 8327012 3250974..3252506 1 NC_013093.1 PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: predicted protein; type I phosphodiesterase/nucleotide pyrophosphatase 3252506 8327012 Amir_2823 Actinosynnema mirum DSM 43827 type I phosphodiesterase/nucleotide pyrophosphatase YP_003100599.1 3250974 D 446462 CDS YP_003100600.1 256376940 8327013 3252503..3253411 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mch:Mchl_0500 ABC transporter; ABC transporter 3253411 8327013 Amir_2824 Actinosynnema mirum DSM 43827 ABC transporter YP_003100600.1 3252503 D 446462 CDS YP_003100601.1 256376941 8327014 3253401..3254162 1 NC_013093.1 PFAM: ABC transporter; KEGG: bte:BTH_I2328 transporter; ABC transporter 3254162 8327014 Amir_2825 Actinosynnema mirum DSM 43827 ABC transporter YP_003100601.1 3253401 D 446462 CDS YP_003100602.1 256376942 8327015 3254217..3254456 1 NC_013093.1 PFAM: phosphopantetheine-binding; KEGG: pol:Bpro_3393 AMP-dependent synthetase and ligase; phosphopantetheine-binding 3254456 8327015 Amir_2826 Actinosynnema mirum DSM 43827 phosphopantetheine-binding YP_003100602.1 3254217 D 446462 CDS YP_003100603.1 256376943 8327017 complement(3255291..3256208) 1 NC_013093.1 PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_2144 NmrA-like family protein; NmrA family protein 3256208 8327017 Amir_2828 Actinosynnema mirum DSM 43827 NmrA family protein YP_003100603.1 3255291 R 446462 CDS YP_003100604.1 256376944 8327018 3256365..3256976 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mxa:MXAN_2145 transcriptional regulator, TetR family; TetR family transcriptional regulator 3256976 8327018 Amir_2829 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100604.1 3256365 D 446462 CDS YP_003100605.1 256376945 8327019 complement(3256957..3257991) 1 NC_013093.1 KEGG: smd:Smed_4158 alanine racemase; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 3257991 8327019 Amir_2830 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003100605.1 3256957 R 446462 CDS YP_003100606.1 256376946 8327020 3258637..3260526 1 NC_013093.1 PFAM: protein of unknown function DUF1680; KEGG: ret:RHE_CH03841 hypothetical protein; hypothetical protein 3260526 8327020 Amir_2831 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100606.1 3258637 D 446462 CDS YP_003100607.1 256376947 8327021 3260564..3261817 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: mlo:mlr2244 sugar binding protein of sugar ABC transporter; family 1 extracellular solute-binding protein 3261817 8327021 Amir_2832 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003100607.1 3260564 D 446462 CDS YP_003100608.1 256376948 8327022 3261825..3262772 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 3262772 8327022 Amir_2833 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100608.1 3261825 D 446462 CDS YP_003100609.1 256376949 8327023 3262787..3263614 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL4375 transmembrane component of ABC transporter; ABC transporter inner membrane protein 3263614 8327023 Amir_2834 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100609.1 3262787 D 446462 CDS YP_003100610.1 256376950 8327024 3263676..3264551 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3264551 8327024 Amir_2835 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100610.1 3263676 D 446462 CDS YP_003100611.1 256376951 8327025 3264702..3266546 1 NC_013093.1 PFAM: protein of unknown function DUF1680; KEGG: hypothetical protein; hypothetical protein 3266546 8327025 Amir_2836 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100611.1 3264702 D 446462 CDS YP_003100612.1 256376952 8327026 3266602..3267648 1 NC_013093.1 PFAM: glycoside hydrolase family 43; KEGG: scl:sce4598 endo-1,4-beta-xylanase; glycoside hydrolase family protein 3267648 8327026 Amir_2837 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003100612.1 3266602 D 446462 CDS YP_003100613.1 256376953 8327027 3267645..3270485 1 NC_013093.1 PFAM: coagulation factor 5/8 type domain protein; KEGG: xcv:XCV2729 secreted protein; coagulation factor 5/8 type domain-containing protein 3270485 8327027 Amir_2838 Actinosynnema mirum DSM 43827 coagulation factor 5/8 type domain-containing protein YP_003100613.1 3267645 D 446462 CDS YP_003100614.1 256376954 8327028 complement(3270537..3272090) 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein 3272090 8327028 Amir_2839 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003100614.1 3270537 R 446462 CDS YP_003100615.1 256376955 8327029 complement(3272204..3272539) 1 NC_013093.1 PFAM: ethyl tert-butyl ether degradation EthD; KEGG: cak:Caul_5271 ethyl tert-butyl ether degradation EthD; ethyl tert-butyl ether degradation protein EthD 3272539 8327029 Amir_2840 Actinosynnema mirum DSM 43827 ethyl tert-butyl ether degradation protein EthD YP_003100615.1 3272204 R 446462 CDS YP_003100616.1 256376956 8327030 3272689..3273066 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcr:BCAH187_A5339 transcriptional regulator, MerR family; MerR family transcriptional regulator 3273066 8327030 Amir_2841 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003100616.1 3272689 D 446462 CDS YP_003100617.1 256376957 8327031 3273281..3274759 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: acp:A2cp1_0906 transcriptional regulator, LuxR family; LuxR family transcriptional regulator 3274759 8327031 Amir_2842 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100617.1 3273281 D 446462 CDS YP_003100618.1 256376958 8327032 complement(3274711..3275091) 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: bja:bll4888 hypothetical protein; endoribonuclease L-PSP 3275091 8327032 Amir_2843 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003100618.1 3274711 R 446462 CDS YP_003100619.1 256376959 8327033 complement(3275193..3275588) 1 NC_013093.1 hypothetical protein 3275588 8327033 Amir_2844 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100619.1 3275193 R 446462 CDS YP_003100620.1 256376960 8327034 complement(3275804..3276457) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dvm:DvMF_1479 transcriptional regulator, GntR family; GntR family transcriptional regulator 3276457 8327034 Amir_2845 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003100620.1 3275804 R 446462 CDS YP_003100621.1 256376961 8327035 complement(3276471..3278195) 1 NC_013093.1 PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: rme:Rmet_5039 acetolactate synthase, large subunit; thiamine pyrophosphate TPP-binding domain-containing protein 3278195 8327035 Amir_2846 Actinosynnema mirum DSM 43827 thiamine pyrophosphate TPP-binding domain-containing protein YP_003100621.1 3276471 R 446462 CDS YP_003100622.1 256376962 8327036 complement(3278192..3279709) 1 NC_013093.1 KEGG: sal:Sala_2314 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein; amidohydrolase 3279709 8327036 Amir_2847 Actinosynnema mirum DSM 43827 amidohydrolase YP_003100622.1 3278192 R 446462 CDS YP_003100623.1 256376963 8327037 complement(3279706..3280626) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4411 luciferase-like; luciferase-like monooxygenase 3280626 8327037 Amir_2848 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100623.1 3279706 R 446462 CDS YP_003100624.1 256376964 8327038 complement(3280623..3282509) 1 NC_013093.1 PFAM: hydantoinase B/oxoprolinase; KEGG: mes:Meso_3732 hydantoinase B/oxoprolinase; 5-oxoprolinase 3282509 8327038 Amir_2849 Actinosynnema mirum DSM 43827 5-oxoprolinase YP_003100624.1 3280623 R 446462 CDS YP_003100625.1 256376965 8327039 complement(3282502..3284574) 1 NC_013093.1 PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; KEGG: mno:Mnod_8488 hydantoinase/oxoprolinase; 5-oxoprolinase 3284574 8327039 Amir_2850 Actinosynnema mirum DSM 43827 5-oxoprolinase YP_003100625.1 3282502 R 446462 CDS YP_003100626.1 256376966 8327040 complement(3284571..3285392) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL100063 ABC transporter permease component; ABC transporter inner membrane protein 3285392 8327040 Amir_2851 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100626.1 3284571 R 446462 CDS YP_003100627.1 256376967 8327041 complement(3285389..3286228) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oca:OCAR_6772 ABC transporter; ABC transporter inner membrane protein 3286228 8327041 Amir_2852 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100627.1 3285389 R 446462 CDS YP_003100628.1 256376968 8327042 complement(3286225..3287322) 1 NC_013093.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: azc:AZC_2725 ABC transporter ATP-binding protein; ABC transporter 3287322 8327042 Amir_2853 Actinosynnema mirum DSM 43827 ABC transporter YP_003100628.1 3286225 R 446462 CDS YP_003100629.1 256376969 8327043 complement(3287324..3288427) 1 NC_013093.1 KEGG: bph:Bphy_6624 extracellular solute-binding protein; spermidine/putrescine-binding periplasmic protein 3288427 8327043 Amir_2854 Actinosynnema mirum DSM 43827 spermidine/putrescine-binding periplasmic protein YP_003100629.1 3287324 R 446462 CDS YP_003100630.1 256376970 8327044 3288721..3289413 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mmw:Mmwyl1_4073 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3289413 8327044 Amir_2855 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100630.1 3288721 D 446462 CDS YP_003100631.1 256376971 8327045 complement(3289517..3290218) 1 NC_013093.1 KEGG: hch:HCH_03068 lysophospholipase; hypothetical protein 3290218 8327045 Amir_2856 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100631.1 3289517 R 446462 CDS YP_003100632.1 256376972 8327046 3290328..3291308 1 NC_013093.1 PFAM: Helix-turn-helix type 11 domain protein; protein of unknown function UPF0074; KEGG: pol:Bpro_0147 helix-turn-helix, type 11; Helix-turn-helix type 11 domain-containing protein 3291308 8327046 Amir_2857 Actinosynnema mirum DSM 43827 Helix-turn-helix type 11 domain-containing protein YP_003100632.1 3290328 D 446462 CDS YP_003100633.1 256376973 8327047 complement(3291609..3293006) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: eum:ECUMN_4826 conserved hypothetical protein mrx; major facilitator superfamily protein 3293006 8327047 Amir_2858 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100633.1 3291609 R 446462 CDS YP_003100634.1 256376974 8327048 3293115..3293675 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: ccs:CCNA_02884 transcriptional regulator, TetR family; TetR family transcriptional regulator 3293675 8327048 Amir_2859 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100634.1 3293115 D 446462 CDS YP_003100635.1 256376975 8327049 complement(3293698..3294435) 1 NC_013093.1 KEGG: mxa:MXAN_2224 hypothetical protein; hypothetical protein 3294435 8327049 Amir_2860 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100635.1 3293698 R 446462 CDS YP_003100636.1 256376976 8327050 3294839..3295240 1 NC_013093.1 KEGG: similar to bromodomain adjacent to zinc finger domain, 1B; K11658 bromodomain adjacent to zinc finger domain protein 1B; hypothetical protein 3295240 8327050 Amir_2861 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100636.1 3294839 D 446462 CDS YP_003100637.1 256376977 8327051 complement(3295237..3296715) 1 NC_013093.1 PFAM: Extracellular ligand-binding receptor; KEGG: cvi:CV_0405 amino acid ABC transporter; Extracellular ligand-binding receptor 3296715 8327051 Amir_2862 Actinosynnema mirum DSM 43827 Extracellular ligand-binding receptor YP_003100637.1 3295237 R 446462 CDS YP_003100638.1 256376978 8327052 complement(3296759..3298456) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3298456 8327052 Amir_2863 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100638.1 3296759 R 446462 CDS YP_003100639.1 256376979 8327054 complement(3299537..3302266) 1 NC_013093.1 KEGG: eca:ECA4303 hypothetical protein; hypothetical protein 3302266 8327054 Amir_2865 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100639.1 3299537 R 446462 CDS YP_003100640.1 256376980 8327055 3302549..3302875 1 NC_013093.1 hypothetical protein 3302875 8327055 Amir_2866 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100640.1 3302549 D 446462 CDS YP_003100641.1 256376981 8327056 3302872..3303567 1 NC_013093.1 KEGG: mpo:Mpop_2368 GLUG domain protein; hypothetical protein 3303567 8327056 Amir_2867 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100641.1 3302872 D 446462 CDS YP_003100642.1 256376982 8327057 complement(3304515..3304679) 1 NC_013093.1 hypothetical protein 3304679 8327057 Amir_2868 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100642.1 3304515 R 446462 CDS YP_003100643.1 256376983 8327058 complement(3304757..3305023) 1 NC_013093.1 hypothetical protein 3305023 8327058 Amir_2869 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100643.1 3304757 R 446462 CDS YP_003100644.1 256376984 8327059 3306210..3312644 1 NC_013093.1 TIGRFAM: YD repeat protein; KEGG: ypp:YPDSF_0222 membrane protein; YD repeat-containing protein 3312644 8327059 Amir_2870 Actinosynnema mirum DSM 43827 YD repeat-containing protein YP_003100644.1 3306210 D 446462 CDS YP_003100645.1 256376985 8327060 complement(3313133..3314707) 1 NC_013093.1 PFAM: Domain of unknown function DUF1814; KEGG: scl:sce3078 hydrolase; hypothetical protein 3314707 8327060 Amir_2871 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100645.1 3313133 R 446462 CDS YP_003100646.1 256376986 8327061 3314890..3315294 1 NC_013093.1 PFAM: Rare lipoprotein A; KEGG: lipoprotein A domain-containing protein; Rare lipoprotein A 3315294 8327061 Amir_2872 Actinosynnema mirum DSM 43827 Rare lipoprotein A YP_003100646.1 3314890 D 446462 CDS YP_003100647.1 256376987 8327062 3315415..3316509 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: dsh:Dshi_0573 periplasmic binding protein; periplasmic binding protein 3316509 8327062 Amir_2873 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003100647.1 3315415 D 446462 CDS YP_003100648.1 256376988 8327063 3316506..3317588 1 NC_013093.1 PFAM: transport system permease protein; KEGG: rce:RC1_3860 hemin transport system permease protein HmuU; transport system permease 3317588 8327063 Amir_2874 Actinosynnema mirum DSM 43827 transport system permease YP_003100648.1 3316506 D 446462 CDS YP_003100649.1 256376989 8327064 3317585..3318403 1 NC_013093.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3318403 hmuV 8327064 hmuV Actinosynnema mirum DSM 43827 hemin importer ATP-binding subunit YP_003100649.1 3317585 D 446462 CDS YP_003100650.1 256376990 8327065 3318403..3319500 1 NC_013093.1 KEGG: cti:RALTA_B2062 conserved hypothetical protein; exported protein; hypothetical protein 3319500 8327065 Amir_2876 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100650.1 3318403 D 446462 CDS YP_003100651.1 256376991 8327066 3319497..3320540 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Htaa domain protein; KEGG: GJ12556 gene product from transcript GJ12556- RA; LPXTG-motif cell wall anchor domain-containing protein 3320540 8327066 Amir_2877 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003100651.1 3319497 D 446462 CDS YP_003100652.1 256376992 8327067 complement(3320578..3321714) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: gdj:Gdia_2837 monooxygenase FAD-binding; FAD-binding monooxygenase 3321714 8327067 Amir_2878 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003100652.1 3320578 R 446462 CDS YP_003100653.1 256376993 8327068 3321789..3322469 1 NC_013093.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: bur:Bcep18194_B0744 TetR family transcriptional regulator; TetR family transcriptional regulator 3322469 8327068 Amir_2879 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100653.1 3321789 D 446462 CDS YP_003100654.1 256376994 8327069 complement(3322501..3323601) 1 NC_013093.1 PFAM: protein of unknown function DUF916 cell surface KEGG: mex:Mext_2409 hypothetical protein; hypothetical protein 3323601 8327069 Amir_2880 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100654.1 3322501 R 446462 CDS YP_003100655.1 256376995 8327070 complement(3323661..3324998) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3324998 8327070 Amir_2881 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100655.1 3323661 R 446462 CDS YP_003100656.1 256376996 8327071 complement(3325147..3325743) 1 NC_013093.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mpt:Mpe_A2158 phosphoribosylanthranilate isomerase; phosphoribosylanthranilate isomerase 3325743 8327071 Amir_2882 Actinosynnema mirum DSM 43827 phosphoribosylanthranilate isomerase YP_003100656.1 3325147 R 446462 CDS YP_003100657.1 256376997 8327072 3325794..3326375 1 NC_013093.1 TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD family protein; HhH-GPD family protein 3326375 8327072 Amir_2883 Actinosynnema mirum DSM 43827 HhH-GPD family protein YP_003100657.1 3325794 D 446462 CDS YP_003100658.1 256376998 8327074 3326757..3329027 1 NC_013093.1 KEGG: YALI0B09867p; hypothetical protein 3329027 8327074 Amir_2885 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100658.1 3326757 D 446462 CDS YP_003100659.1 256376999 8327075 3329188..3330075 1 NC_013093.1 KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein 3330075 8327075 Amir_2886 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100659.1 3329188 D 446462 CDS YP_003100660.1 256377000 8327076 complement(3330390..3330704) 1 NC_013093.1 PFAM: small multidrug resistance protein; KEGG: pzu:PHZ_c0240 small multidrug resistance protein; small multidrug resistance protein 3330704 8327076 Amir_2887 Actinosynnema mirum DSM 43827 small multidrug resistance protein YP_003100660.1 3330390 R 446462 CDS YP_003100661.1 256377001 8327077 complement(3331030..3332478) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: sal:Sala_0898 major facilitator transporter; major facilitator superfamily protein 3332478 8327077 Amir_2888 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100661.1 3331030 R 446462 CDS YP_003100662.1 256377002 8327078 3332639..3333322 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: pla:Plav_0388 TetR family transcriptional regulator; TetR family transcriptional regulator 3333322 8327078 Amir_2889 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100662.1 3332639 D 446462 CDS YP_003100663.1 256377003 8327079 3333994..3334248 1 NC_013093.1 KEGG: cell wall protein; hypothetical protein 3334248 8327079 Amir_2890 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100663.1 3333994 D 446462 CDS YP_003100664.1 256377004 8327080 3334245..3334955 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: swi:Swit_1768 regulatory protein, TetR; TetR family transcriptional regulator 3334955 8327080 Amir_2891 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100664.1 3334245 D 446462 CDS YP_003100665.1 256377005 8327081 3334952..3335152 1 NC_013093.1 PFAM: protein of unknown function DUF1271; KEGG: bxe:Bxe_C0944 ferredoxin; hypothetical protein 3335152 8327081 Amir_2892 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100665.1 3334952 D 446462 CDS YP_003100666.1 256377006 8327082 3335149..3336585 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: met:M446_4600 cyclic nucleotide-binding protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 3336585 8327082 Amir_2893 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003100666.1 3335149 D 446462 CDS YP_003100667.1 256377007 8327083 3336582..3337805 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 3337805 8327083 Amir_2894 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100667.1 3336582 D 446462 CDS YP_003100668.1 256377008 8327084 3337898..3339103 1 NC_013093.1 PFAM: cytochrome P450; KEGG: CYP55B1; cytochrome P450, nitric oxide reductase; cytochrome P450 3339103 8327084 Amir_2895 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100668.1 3337898 D 446462 CDS YP_003100669.1 256377009 8327085 3339117..3340109 1 NC_013093.1 TIGRFAM: glycosyltransferase, MGT family; PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; glycosyltransferase 28 domain; KEGG: ses:SARI_00205 hypothetical protein; MGT family glycosyltransferase 3340109 8327085 Amir_2896 Actinosynnema mirum DSM 43827 MGT family glycosyltransferase YP_003100669.1 3339117 D 446462 CDS YP_003100670.1 256377010 8327086 3340812..3342527 1 NC_013093.1 PFAM: histidine kinase A domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: bxe:Bxe_A0786 lipoprotein; histidine kinase 3342527 8327086 Amir_2897 Actinosynnema mirum DSM 43827 histidine kinase YP_003100670.1 3340812 D 446462 CDS YP_003100671.1 256377011 8327087 complement(3342548..3343396) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcz:pE33L466_0331 MerR family transcriptional regulator; MerR family transcriptional regulator 3343396 8327087 Amir_2898 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003100671.1 3342548 R 446462 CDS YP_003100672.1 256377012 8327088 complement(3343645..3345093) 1 NC_013093.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: reu:Reut_C6231 hypothetical protein; amidohydrolase 3345093 8327088 Amir_2899 Actinosynnema mirum DSM 43827 amidohydrolase YP_003100672.1 3343645 R 446462 CDS YP_003100673.1 256377013 8327089 3345176..3345781 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: xau:Xaut_3070 TetR family transcriptional regulator; TetR family transcriptional regulator 3345781 8327089 Amir_2900 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100673.1 3345176 D 446462 CDS YP_003100674.1 256377014 8327090 complement(3345848..3347203) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: pen:PSEEN2716 non-ribosomal peptide synthetase; AMP-dependent synthetase and ligase 3347203 8327090 Amir_2901 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003100674.1 3345848 R 446462 CDS YP_003100675.1 256377015 8327096 3351047..3352924 1 NC_013093.1 KEGG: GD20599 gene product from transcript GD20599- RA; hypothetical protein 3352924 8327096 Amir_2907 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100675.1 3351047 D 446462 CDS YP_003100676.1 256377016 8327097 complement(3352971..3354476) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: extracellular solute-binding protein; K02035 peptide/nickel transport system substrate-binding protein; family 5 extracellular solute-binding protein 3354476 8327097 Amir_2908 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003100676.1 3352971 R 446462 CDS YP_003100677.1 256377017 8327098 3355008..3358358 1 NC_013093.1 KEGG: efe:EFER_2201 molybdate metabolism regulator (MolR); hypothetical protein 3358358 8327098 Amir_2909 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100677.1 3355008 D 446462 CDS YP_003100678.1 256377018 8327099 complement(3358541..3360892) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-2 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; KEGG: sml:Smlt2382 two-component sensor histidine kinase protein; multi-sensor signal transduction histidine kinase 3360892 8327099 Amir_2910 Actinosynnema mirum DSM 43827 multi-sensor signal transduction histidine kinase YP_003100678.1 3358541 R 446462 CDS YP_003100679.1 256377019 8327100 3361009..3362985 1 NC_013093.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sus:Acid_5974 serine phosphatase; protein serine/threonine phosphatase 3362985 8327100 Amir_2911 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003100679.1 3361009 D 446462 CDS YP_003100680.1 256377020 8327101 3362964..3363389 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mag:amb3470 FOG: CheY-like receiver; response regulator receiver protein 3363389 8327101 Amir_2912 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003100680.1 3362964 D 446462 CDS YP_003100681.1 256377021 8327102 3363559..3363855 1 NC_013093.1 hypothetical protein 3363855 8327102 Amir_2913 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100681.1 3363559 D 446462 CDS YP_003100682.1 256377022 8327104 3366125..3366565 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: mxa:MXAN_5099 transcriptional regulator; HxlR family transcriptional regulator 3366565 8327104 Amir_2915 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003100682.1 3366125 D 446462 CDS YP_003100683.1 256377023 8327105 3366690..3367475 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cak:Caul_1370 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3367475 8327105 Amir_2916 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100683.1 3366690 D 446462 CDS YP_003100684.1 256377024 8327106 complement(3367435..3368103) 1 NC_013093.1 KEGG: hypothetical protein LOC686639; hypothetical protein 3368103 8327106 Amir_2917 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100684.1 3367435 R 446462 CDS YP_003100685.1 256377025 8327107 complement(3368109..3368981) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL120663 permease component of ABC transporter; ABC transporter inner membrane protein 3368981 8327107 Amir_2918 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100685.1 3368109 R 446462 CDS YP_003100686.1 256377026 8327108 complement(3368978..3369910) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ABC transporter membrane spanning protein (sugar); K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 3369910 8327108 Amir_2919 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100686.1 3368978 R 446462 CDS YP_003100687.1 256377027 8327109 complement(3369915..3371189) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: rle:pRL120659 substrate-binding component of ABC transporter; family 1 extracellular solute-binding protein 3371189 8327109 Amir_2920 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003100687.1 3369915 R 446462 CDS YP_003100688.1 256377028 8327110 complement(3371235..3373190) 1 NC_013093.1 KEGG: ret:RHE_CH00075 hypothetical protein; hypothetical protein 3373190 8327110 Amir_2921 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100688.1 3371235 R 446462 CDS YP_003100689.1 256377029 8327111 complement(3373187..3374167) 1 NC_013093.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rlt:Rleg2_4009 D-isomer specific 2- hydroxyacid dehydrogenase NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 3374167 8327111 Amir_2922 Actinosynnema mirum DSM 43827 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_003100689.1 3373187 R 446462 CDS YP_003100690.1 256377030 8327112 3374356..3375444 1 NC_013093.1 PFAM: regulatory protein DeoR; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein DeoR; KEGG: ppw:PputW619_1959 LacI family transcription regulator; DeoR family transcriptional regulator 3375444 8327112 Amir_2923 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003100690.1 3374356 D 446462 CDS YP_003100691.1 256377031 8327113 3375820..3376701 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: ade:Adeh_2416 hypothetical protein; hypothetical protein 3376701 8327113 Amir_2924 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100691.1 3375820 D 446462 CDS YP_003100692.1 256377032 8327114 complement(3376705..3378711) 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; SARP family transcriptional regulator 3378711 8327114 Amir_2925 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003100692.1 3376705 R 446462 CDS YP_003100693.1 256377033 8327115 3378911..3379252 1 NC_013093.1 hypothetical protein 3379252 8327115 Amir_2926 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100693.1 3378911 D 446462 CDS YP_003100694.1 256377034 8327116 3379249..3379506 1 NC_013093.1 hypothetical protein 3379506 8327116 Amir_2927 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100694.1 3379249 D 446462 CDS YP_003100695.1 256377035 8327117 3380126..3380290 1 NC_013093.1 hypothetical protein 3380290 8327117 Amir_2928 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100695.1 3380126 D 446462 CDS YP_003100696.1 256377036 8327118 complement(3380342..3381685) 1 NC_013093.1 KEGG: GM17356 gene product from transcript GM17356- RA; hypothetical protein 3381685 8327118 Amir_2929 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100696.1 3380342 R 446462 CDS YP_003100697.1 256377037 8327119 3381835..3382461 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: bcy:Bcer98_1160 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 3382461 8327119 Amir_2930 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100697.1 3381835 D 446462 CDS YP_003100698.1 256377038 8327120 3382591..3385680 1 NC_013093.1 PFAM: hypothetical protein; KEGG: ade:Adeh_2230 hypothetical protein; hypothetical protein 3385680 8327120 Amir_2931 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100698.1 3382591 D 446462 CDS YP_003100699.1 256377039 8327121 3385733..3386458 1 NC_013093.1 KEGG: plu:plu1715 hypothetical protein; hypothetical protein 3386458 8327121 Amir_2932 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100699.1 3385733 D 446462 CDS YP_003100700.1 256377040 8327122 3386532..3388601 1 NC_013093.1 PFAM: ATPase AAA; SMART: ATPase AAA; KEGG: noc:Noc_1879 ATPase AAA; ATPase AAA 3388601 8327122 Amir_2933 Actinosynnema mirum DSM 43827 ATPase AAA YP_003100700.1 3386532 D 446462 CDS YP_003100701.1 256377041 8327123 complement(3388642..3389502) 1 NC_013093.1 KEGG: aci:ACIAD3520 hypothetical protein; hypothetical protein 3389502 8327123 Amir_2934 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100701.1 3388642 R 446462 CDS YP_003100702.1 256377042 8327124 3389649..3390107 1 NC_013093.1 hypothetical protein 3390107 8327124 Amir_2935 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100702.1 3389649 D 446462 CDS YP_003100703.1 256377043 8327125 complement(3390127..3393291) 1 NC_013093.1 PFAM: transcriptional activator domain; TPR repeat- containing protein; hypothetical protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce6858 hypothetical protein; SARP family transcriptional regulator 3393291 8327125 Amir_2936 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003100703.1 3390127 R 446462 CDS YP_003100704.1 256377044 8327126 3393516..3393725 1 NC_013093.1 KEGG: bpy:Bphyt_1629 pseudouridine synthase; pseudouridine synthase 3393725 8327126 Amir_2937 Actinosynnema mirum DSM 43827 pseudouridine synthase YP_003100704.1 3393516 D 446462 CDS YP_003100705.1 256377045 8327127 3394111..3395640 1 NC_013093.1 PFAM: tail sheath protein; KEGG: mlo:mlr6548 hypothetical protein; tail sheath protein 3395640 8327127 Amir_2938 Actinosynnema mirum DSM 43827 tail sheath protein YP_003100705.1 3394111 D 446462 CDS YP_003100706.1 256377046 8327128 3395687..3396127 1 NC_013093.1 TIGRFAM: conserved hypothetical protein; KEGG: gsu:GSU0979 hypothetical protein; hypothetical protein 3396127 8327128 Amir_2939 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100706.1 3395687 D 446462 CDS YP_003100707.1 256377047 8327129 3396124..3396624 1 NC_013093.1 KEGG: gsu:GSU0977 hypothetical protein; hypothetical protein 3396624 8327129 Amir_2940 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100707.1 3396124 D 446462 CDS YP_003100708.1 256377048 8327130 3396621..3396779 1 NC_013093.1 KEGG: mlo:msr6553 hypothetical protein; hypothetical protein 3396779 8327130 Amir_2941 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100708.1 3396621 D 446462 CDS YP_003100709.1 256377049 8327131 3396884..3399646 1 NC_013093.1 KEGG: proteophosphoglycan 5; hypothetical protein 3399646 8327131 Amir_2942 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100709.1 3396884 D 446462 CDS YP_003100710.1 256377050 8327132 3399697..3400122 1 NC_013093.1 TIGRFAM: conserved hypothetical protein; KEGG: noc:Noc_1873 phage tail region protein; hypothetical protein 3400122 8327132 Amir_2943 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100710.1 3399697 D 446462 CDS YP_003100711.1 256377051 8327133 3400147..3400857 1 NC_013093.1 PFAM: peptidoglycan-binding LysM; KEGG: gsu:GSU0981 hypothetical protein; peptidoglycan-binding LysM 3400857 8327133 Amir_2944 Actinosynnema mirum DSM 43827 peptidoglycan-binding LysM YP_003100711.1 3400147 D 446462 CDS YP_003100712.1 256377052 8327134 3400854..3402623 1 NC_013093.1 TIGRFAM: Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: gbm:Gbem_2550 rhs element Vgr protein; Rhs element Vgr protein 3402623 8327134 Amir_2945 Actinosynnema mirum DSM 43827 Rhs element Vgr protein YP_003100712.1 3400854 D 446462 CDS YP_003100713.1 256377053 8327135 3402657..3402968 1 NC_013093.1 PFAM: hypothetical protein; KEGG: sde:Sde_1043 hypothetical protein; hypothetical protein 3402968 8327135 Amir_2946 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100713.1 3402657 D 446462 CDS YP_003100714.1 256377054 8327136 3402965..3403372 1 NC_013093.1 PFAM: GPW/gp25 family protein; KEGG: gsu:GSU0986 tail lysozyme; GPW/gp25 family protein 3403372 8327136 Amir_2947 Actinosynnema mirum DSM 43827 GPW/gp25 family protein YP_003100714.1 3402965 D 446462 CDS YP_003100715.1 256377055 8327137 3403372..3405324 1 NC_013093.1 KEGG: gsu:GSU0988 hypothetical protein; hypothetical protein 3405324 8327137 Amir_2948 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100715.1 3403372 D 446462 CDS YP_003100716.1 256377056 8327138 3405321..3405896 1 NC_013093.1 TIGRFAM: phage tail protein; KEGG: rsq:Rsph17025_4353 hypothetical protein; phage tail protein 3405896 8327138 Amir_2949 Actinosynnema mirum DSM 43827 phage tail protein YP_003100716.1 3405321 D 446462 CDS YP_003100717.1 256377057 8327139 3406304..3407299 1 NC_013093.1 KEGG: similar to Enabled protein homolog; K05746 enabled; hypothetical protein 3407299 8327139 Amir_2950 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100717.1 3406304 D 446462 CDS YP_003100718.1 256377058 8327140 3407328..3408353 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: mgm:Mmc1_2871 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 3408353 8327140 Amir_2951 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003100718.1 3407328 D 446462 CDS YP_003100719.1 256377059 8327141 3408427..3409050 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: bcy:Bcer98_0214 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 3409050 8327141 Amir_2952 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100719.1 3408427 D 446462 CDS YP_003100720.1 256377060 8327142 3409052..3409291 1 NC_013093.1 hypothetical protein 3409291 8327142 Amir_2953 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100720.1 3409052 D 446462 CDS YP_003100721.1 256377061 8327143 complement(3409582..3413022) 1 NC_013093.1 PFAM: transcriptional activator domain; hypothetical protein; transcriptional regulator domain protein; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; transcriptional regulator 3413022 8327143 Amir_2954 Actinosynnema mirum DSM 43827 transcriptional regulator YP_003100721.1 3409582 R 446462 CDS YP_003100722.1 256377062 8327144 complement(3413019..3413336) 1 NC_013093.1 KEGG: bbr:BB2134 hypothetical protein; hypothetical protein 3413336 8327144 Amir_2955 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100722.1 3413019 R 446462 CDS YP_003100723.1 256377063 8327145 complement(3413350..3417369) 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: bpm:BURPS1710b_1102 lipoprotein; transcriptional regulator 3417369 8327145 Amir_2956 Actinosynnema mirum DSM 43827 transcriptional regulator YP_003100723.1 3413350 R 446462 CDS YP_003100724.1 256377064 8327146 3418122..3418556 1 NC_013093.1 PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 3418556 8327146 Amir_2957 Actinosynnema mirum DSM 43827 UspA domain-containing protein YP_003100724.1 3418122 D 446462 CDS YP_003100725.1 256377065 8327147 3418810..3419277 1 NC_013093.1 hypothetical protein 3419277 8327147 Amir_2958 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100725.1 3418810 D 446462 CDS YP_003100726.1 256377066 8327148 3419337..3420461 1 NC_013093.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pat:Patl_1928 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 3420461 8327148 Amir_2959 Actinosynnema mirum DSM 43827 NADH:flavin oxidoreductase/NADH oxidase YP_003100726.1 3419337 D 446462 CDS YP_003100727.1 256377067 8327149 3420792..3421010 1 NC_013093.1 hypothetical protein 3421010 8327149 Amir_2960 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100727.1 3420792 D 446462 CDS YP_003100728.1 256377068 8327150 complement(3421087..3421671) 1 NC_013093.1 KEGG: cvi:CV_3666 acetyltransferase; hypothetical protein 3421671 8327150 Amir_2961 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100728.1 3421087 R 446462 CDS YP_003100729.1 256377069 8327151 complement(3421661..3422005) 1 NC_013093.1 KEGG: GM10273 gene product from transcript GM10273- RA; hypothetical protein 3422005 8327151 Amir_2962 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100729.1 3421661 R 446462 CDS YP_003100730.1 256377070 8327152 complement(3422077..3422538) 1 NC_013093.1 hypothetical protein 3422538 8327152 Amir_2963 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100730.1 3422077 R 446462 CDS YP_003100731.1 256377071 8327153 3423093..3425117 1 NC_013093.1 KEGG: cti:RALTA_A1696 DNA ligase; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD- dependent DNA ligase OB-fold; SMART: NAD-dependent DNA ligase; BRCT domain protein; Helix-hairpin-helix DNA-binding class 1; DNA ligase, NAD-dependent 3425117 8327153 Amir_2964 Actinosynnema mirum DSM 43827 DNA ligase, NAD-dependent YP_003100731.1 3423093 D 446462 CDS YP_003100732.1 256377072 8327155 3428249..3431500 1 NC_013093.1 KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 3431500 8327155 Amir_2966 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100732.1 3428249 D 446462 CDS YP_003100733.1 256377073 8327156 complement(3431766..3432920) 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: dvl:Dvul_2797 aminotransferase, class I and II; class I and II aminotransferase 3432920 8327156 Amir_2967 Actinosynnema mirum DSM 43827 class I and II aminotransferase YP_003100733.1 3431766 R 446462 CDS YP_003100734.1 256377074 8327157 3432871..3434229 1 NC_013093.1 KEGG: xca:xccb100_4160 secreted hydrolase; hypothetical protein 3434229 8327157 Amir_2968 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100734.1 3432871 D 446462 CDS YP_003100735.1 256377075 8327158 3434570..3435088 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: mpt:Mpe_A0358 two-component sensor histidine kinase-like protein; signal transduction histidine kinase 3435088 8327158 Amir_2969 Actinosynnema mirum DSM 43827 signal transduction histidine kinase YP_003100735.1 3434570 D 446462 CDS YP_003100736.1 256377076 8327159 3435371..3436999 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: sde:Sde_0644 hypothetical protein; TAP domain-containing protein 3436999 8327159 Amir_2970 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003100736.1 3435371 D 446462 CDS YP_003100737.1 256377077 8327160 3437157..3438014 1 NC_013093.1 KEGG: hypothetical protein; K10592 E3 ubiquitin- protein ligase HUWE1; hypothetical protein 3438014 8327160 Amir_2971 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100737.1 3437157 D 446462 CDS YP_003100738.1 256377078 8327161 3438326..3439063 1 NC_013093.1 PFAM: xylose isomerase; KEGG: lch:Lcho_4327 xylose isomerase domain- containing protein; xylose isomerase 3439063 8327161 Amir_2972 Actinosynnema mirum DSM 43827 xylose isomerase YP_003100738.1 3438326 D 446462 CDS YP_003100739.1 256377079 8327162 3439060..3440160 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: rec:RHECIAT_CH0002098 dehydrogenase protein; oxidoreductase domain-containing protein 3440160 8327162 Amir_2973 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003100739.1 3439060 D 446462 CDS YP_003100740.1 256377080 8327163 complement(3440231..3440830) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: pst:PSPTO_3319 TetR family transcriptional regulator; TetR family transcriptional regulator 3440830 8327163 Amir_2974 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100740.1 3440231 R 446462 CDS YP_003100741.1 256377081 8327164 complement(3440915..3441352) 1 NC_013093.1 hypothetical protein 3441352 8327164 Amir_2975 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100741.1 3440915 R 446462 CDS YP_003100742.1 256377082 8327165 complement(3441467..3441955) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: bce:BC3339 phosphohydrolase (MutT/NUDIX family protein); NUDIX hydrolase 3441955 8327165 Amir_2976 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003100742.1 3441467 R 446462 CDS YP_003100743.1 256377083 8327166 complement(3442342..3442932) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: psb:Psyr_3154 regulatory protein, TetR; TetR family transcriptional regulator 3442932 8327166 Amir_2977 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100743.1 3442342 R 446462 CDS YP_003100744.1 256377084 8327167 complement(3442929..3444758) 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: beta-glucosidase-related glycosidases; xylan 1,4-beta-xylosidase 3444758 8327167 Amir_2978 Actinosynnema mirum DSM 43827 xylan 1,4-beta-xylosidase YP_003100744.1 3442929 R 446462 CDS YP_003100745.1 256377085 8327168 3444924..3446189 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: floR; florfenicol/chloramphenicol resistance transporter protein; major facilitator superfamily protein 3446189 8327168 Amir_2979 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100745.1 3444924 D 446462 CDS YP_003100746.1 256377086 8327169 3446316..3447131 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: rle:RL4049 hypothetical protein; XRE family transcriptional regulator 3447131 8327169 Amir_2980 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100746.1 3446316 D 446462 CDS YP_003100747.1 256377087 8327170 3447220..3448005 1 NC_013093.1 PFAM: protein of unknown function DUF1684; KEGG: acp:A2cp1_0109 protein of unknown function DUF1684; hypothetical protein 3448005 8327170 Amir_2981 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100747.1 3447220 D 446462 CDS YP_003100748.1 256377088 8327171 complement(3448316..3448660) 1 NC_013093.1 KEGG: eli:ELI_10905 hypothetical protein; hypothetical protein 3448660 8327171 Amir_2982 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100748.1 3448316 R 446462 CDS YP_003100749.1 256377089 8327172 3448844..3450121 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: sugar ABC transporter; family 1 extracellular solute-binding protein 3450121 8327172 Amir_2983 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003100749.1 3448844 D 446462 CDS YP_003100750.1 256377090 8327173 3450118..3451035 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 3451035 8327173 Amir_2984 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100750.1 3450118 D 446462 CDS YP_003100751.1 256377091 8327174 3451035..3451847 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rec:RHECIAT_PC0000203 sugar ABC transporter, permease protein; ABC transporter inner membrane protein 3451847 8327174 Amir_2985 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100751.1 3451035 D 446462 CDS YP_003100752.1 256377092 8327175 3451844..3454093 1 NC_013093.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI 3454093 8327175 Amir_2986 Actinosynnema mirum DSM 43827 alpha-xylosidase YicI YP_003100752.1 3451844 D 446462 CDS YP_003100753.1 256377093 8327176 complement(3454204..3455175) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: mmr:Mmar10_0065 ArsR family transcriptional regulator; ArsR family transcriptional regulator 3455175 8327176 Amir_2987 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003100753.1 3454204 R 446462 CDS YP_003100754.1 256377094 8327177 complement(3455322..3456308) 1 NC_013093.1 PFAM: regulatory protein LacI; SMART: regulatory protein LacI; KEGG: bam:Bamb_4929 LacI family transcription regulator; LacI family transcriptional regulator 3456308 8327177 Amir_2988 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003100754.1 3455322 R 446462 CDS YP_003100755.1 256377095 8327178 3456484..3456630 1 NC_013093.1 hypothetical protein 3456630 8327178 Amir_2989 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100755.1 3456484 D 446462 CDS YP_003100756.1 256377096 8327180 3457371..3459527 1 NC_013093.1 KEGG: bcb:BCB4264_A3230 hypothetical cytosolic protein; hypothetical protein 3459527 8327180 Amir_2990 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100756.1 3457371 D 446462 CDS YP_003100757.1 256377097 8327181 3459797..3460516 1 NC_013093.1 KEGG: dol:Dole_2720 hypothetical protein; hypothetical protein 3460516 8327181 Amir_2991 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100757.1 3459797 D 446462 CDS YP_003100758.1 256377098 8327182 3460625..3461191 1 NC_013093.1 PFAM: helix-turn-helix domain protein; cupin; SMART: helix-turn-helix domain protein; KEGG: transcriptional regulator protein; XRE family transcriptional regulator 3461191 8327182 Amir_2992 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100758.1 3460625 D 446462 CDS YP_003100759.1 256377099 8327183 3461305..3462192 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: acp:A2cp1_1436 methyltransferase type 11; type 12 methyltransferase 3462192 8327183 Amir_2993 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003100759.1 3461305 D 446462 CDS YP_003100760.1 256377100 8327184 3462234..3462947 1 NC_013093.1 KEGG: hch:HCH_03879 hypothetical protein; hypothetical protein 3462947 8327184 Amir_2994 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100760.1 3462234 D 446462 CDS YP_003100761.1 256377101 8327185 3462954..3463607 1 NC_013093.1 hypothetical protein 3463607 8327185 Amir_2995 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100761.1 3462954 D 446462 CDS YP_003100762.1 256377102 8327186 complement(3463655..3464662) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: bcj:BCAM1529 hydrolase; alpha/beta hydrolase fold protein 3464662 8327186 Amir_2996 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003100762.1 3463655 R 446462 CDS YP_003100763.1 256377103 8327187 complement(3464694..3465161) 1 NC_013093.1 PFAM: protein of unknown function DUF664; hypothetical protein 3465161 8327187 Amir_2997 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100763.1 3464694 R 446462 CDS YP_003100764.1 256377104 8327188 complement(3465183..3465794) 1 NC_013093.1 PFAM: methyltransferase type 11; Tellurite resistance methyltransferase, TehB, core; thiopurine S- methyltransferase; methyltransferase type 12; KEGG: methyltransferase type 12; type 11 methyltransferase 3465794 8327188 Amir_2998 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003100764.1 3465183 R 446462 CDS YP_003100765.1 256377105 8327189 3465882..3466484 1 NC_013093.1 PFAM: helix-turn-helix domain protein; cupin; SMART: helix-turn-helix domain protein; KEGG: reh:H16_B1998 transcriptional regulator, XRE- family; XRE family transcriptional regulator 3466484 8327189 Amir_2999 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003100765.1 3465882 D 446462 CDS YP_003100766.1 256377106 8327190 complement(3466536..3467354) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rso:RSc0215 short chain dehydrogenase; short chain dehydrogenase 3467354 8327190 Amir_3000 Actinosynnema mirum DSM 43827 short chain dehydrogenase YP_003100766.1 3466536 R 446462 CDS YP_003100767.1 256377107 8327191 3467421..3468044 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: afw:Anae109_0884 TetR family transcriptional regulator; TetR family transcriptional regulator 3468044 8327191 Amir_3001 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100767.1 3467421 D 446462 CDS YP_003100768.1 256377108 8327192 3468612..3469730 1 NC_013093.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: tmz:Tmz1t_2342 exonuclease RNase T and DNA polymerase III; exonuclease RNase T and DNA polymerase III 3469730 8327192 Amir_3002 Actinosynnema mirum DSM 43827 exonuclease RNase T and DNA polymerase III YP_003100768.1 3468612 D 446462 CDS YP_003100769.1 256377109 8327193 3469770..3470789 1 NC_013093.1 PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; KEGG: cja:CJA_2025 MerR-family transcriptional regulator; MerR family transcriptional regulator 3470789 8327193 Amir_3003 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003100769.1 3469770 D 446462 CDS YP_003100770.1 256377110 8327194 complement(3470839..3471510) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 3471510 8327194 Amir_3004 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100770.1 3470839 R 446462 CDS YP_003100771.1 256377111 8327195 complement(3471507..3472670) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3472670 8327195 Amir_3005 Actinosynnema mirum DSM 43827 histidine kinase YP_003100771.1 3471507 R 446462 CDS YP_003100772.1 256377112 8327196 3472791..3473564 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0970 ABC transporter, ATPase subunit; ABC transporter 3473564 8327196 Amir_3006 Actinosynnema mirum DSM 43827 ABC transporter YP_003100772.1 3472791 D 446462 CDS YP_003100773.1 256377113 8327197 3473564..3475969 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: aeh:Mlg_1312 hypothetical protein; hypothetical protein 3475969 8327197 Amir_3007 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100773.1 3473564 D 446462 CDS YP_003100774.1 256377114 8327198 complement(3476013..3477188) 1 NC_013093.1 PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; PglZ domain protein; KEGG: tbd:Tbd_1468 hypothetical protein; type I phosphodiesterase/nucleotide pyrophosphatase 3477188 8327198 Amir_3008 Actinosynnema mirum DSM 43827 type I phosphodiesterase/nucleotide pyrophosphatase YP_003100774.1 3476013 R 446462 CDS YP_003100775.1 256377115 8327199 3477602..3479269 1 NC_013093.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: lch:Lcho_3323 alpha amylase catalytic region; alpha amylase catalytic subunit 3479269 8327199 Amir_3009 Actinosynnema mirum DSM 43827 alpha amylase catalytic subunit YP_003100775.1 3477602 D 446462 CDS YP_003100776.1 256377116 8327200 3479435..3479821 1 NC_013093.1 KEGG: pag:PLES_32071 hypothetical protein; hypothetical protein 3479821 8327200 Amir_3010 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100776.1 3479435 D 446462 CDS YP_003100777.1 256377117 8327201 complement(3480056..3480805) 1 NC_013093.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: afw:Anae109_2808 NADP oxidoreductase coenzyme F420-dependent; NADP oxidoreductase coenzyme F420-dependent 3480805 8327201 Amir_3011 Actinosynnema mirum DSM 43827 NADP oxidoreductase coenzyme F420-dependent YP_003100777.1 3480056 R 446462 CDS YP_003100778.1 256377118 8327202 3480917..3481576 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bbt:BBta_0873 TetR family transcriptional regulator; TetR family transcriptional regulator 3481576 8327202 Amir_3012 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100778.1 3480917 D 446462 CDS YP_003100779.1 256377119 8327203 3482195..3482704 1 NC_013093.1 hypothetical protein 3482704 8327203 Amir_3013 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100779.1 3482195 D 446462 CDS YP_003100780.1 256377120 8327204 3483618..3484118 1 NC_013093.1 hypothetical protein 3484118 8327204 Amir_3014 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100780.1 3483618 D 446462 CDS YP_003100781.1 256377121 8327205 complement(3484096..3485427) 1 NC_013093.1 PFAM: sodium/calcium exchanger membrane region; KEGG: dvl:Dvul_0633 sodium/calcium exchanger membrane region; sodium/calcium exchanger membrane protein 3485427 8327205 Amir_3015 Actinosynnema mirum DSM 43827 sodium/calcium exchanger membrane protein YP_003100781.1 3484096 R 446462 CDS YP_003100782.1 256377122 8327206 3485551..3486378 1 NC_013093.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; siderophore-interacting protein; KEGG: pag:PLES_28941 SIP; FAD-binding 9 siderophore-interacting domain-containing protein 3486378 8327206 Amir_3016 Actinosynnema mirum DSM 43827 FAD-binding 9 siderophore-interacting domain-containing protein YP_003100782.1 3485551 D 446462 CDS YP_003100783.1 256377123 8327208 complement(3487470..3488300) 1 NC_013093.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: phenazine biosynthesis PhzC/PhzF protein; KEGG: acr:Acry_0325 PhzF family phenazine biosynthesis protein; phenazine biosynthesis protein PhzF family 3488300 8327208 Amir_3018 Actinosynnema mirum DSM 43827 phenazine biosynthesis protein PhzF family YP_003100783.1 3487470 R 446462 CDS YP_003100784.1 256377124 8327209 complement(3488359..3488982) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bmu:Bmul_5991 TetR family transcriptional regulator; TetR family transcriptional regulator 3488982 8327209 Amir_3019 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100784.1 3488359 R 446462 CDS YP_003100785.1 256377125 8327210 3489110..3489667 1 NC_013093.1 PFAM: NADPH-dependent FMN reductase; NAD(P)H dehydrogenase (quinone); KEGG: rsp:RSP_3069 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 3489667 8327210 Amir_3020 Actinosynnema mirum DSM 43827 NADPH-dependent FMN reductase YP_003100785.1 3489110 D 446462 CDS YP_003100786.1 256377126 8327211 3489781..3493725 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 3493725 8327211 Amir_3021 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100786.1 3489781 D 446462 CDS YP_003100787.1 256377127 8327212 complement(3493870..3494058) 1 NC_013093.1 hypothetical protein 3494058 8327212 Amir_3022 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100787.1 3493870 R 446462 CDS YP_003100788.1 256377128 8327213 complement(3494051..3494509) 1 NC_013093.1 KEGG: gme:Gmet_1196 PASTA; hypothetical protein 3494509 8327213 Amir_3023 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100788.1 3494051 R 446462 CDS YP_003100789.1 256377129 8327214 3494948..3495733 1 NC_013093.1 PFAM: inositol monophosphatase; KEGG: mgm:Mmc1_0078 inositol-phosphate phosphatase; inositol-phosphate phosphatase 3495733 8327214 Amir_3024 Actinosynnema mirum DSM 43827 inositol-phosphate phosphatase YP_003100789.1 3494948 D 446462 CDS YP_003100790.1 256377130 8327215 3495991..3497850 1 NC_013093.1 PFAM: ABC transporter transmembrane protein; ABC transporter; KEGG: mpo:Mpop_2313 lipid A ABC exporter family, fused ATPase and inner membrane subunits; ABC transporter transmembrane protein 3497850 8327215 Amir_3025 Actinosynnema mirum DSM 43827 ABC transporter transmembrane protein YP_003100790.1 3495991 D 446462 CDS YP_003100791.1 256377131 8327216 3497847..3499679 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: maq:Maqu_2187 ABC transporter; ABC transporter 3499679 8327216 Amir_3026 Actinosynnema mirum DSM 43827 ABC transporter YP_003100791.1 3497847 D 446462 CDS YP_003100792.1 256377132 8327217 complement(3500217..3500906) 1 NC_013093.1 PFAM: glycoside hydrolase family 12; KEGG: bja:blr1964 hypothetical protein; hypothetical protein 3500906 8327217 Amir_3027 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100792.1 3500217 R 446462 CDS YP_003100793.1 256377133 8327218 complement(3501226..3502983) 1 NC_013093.1 KEGG: xcb:XC_4318 avirulence protein; avirulence protein 3502983 8327218 Amir_3028 Actinosynnema mirum DSM 43827 avirulence protein YP_003100793.1 3501226 R 446462 CDS YP_003100794.1 256377134 8327219 3503343..3503639 1 NC_013093.1 KEGG: similar to DNA Helicase; hypothetical protein 3503639 8327219 Amir_3029 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100794.1 3503343 D 446462 CDS YP_003100795.1 256377135 8327220 complement(3503718..3504125) 1 NC_013093.1 hypothetical protein 3504125 8327220 Amir_3030 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100795.1 3503718 R 446462 CDS YP_003100796.1 256377136 8327221 3504246..3504638 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: swi:Swit_1410 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 3504638 8327221 Amir_3031 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003100796.1 3504246 D 446462 CDS YP_003100797.1 256377137 8327222 3504730..3506376 1 NC_013093.1 KEGG: rsh:Rsph17029_3222 hypothetical protein; kinase-like protein 3506376 8327222 Amir_3032 Actinosynnema mirum DSM 43827 kinase-like protein YP_003100797.1 3504730 D 446462 CDS YP_003100798.1 256377138 8327223 3506376..3509063 1 NC_013093.1 PFAM: endonuclease/exonuclease/phosphatase; phosphoesterase HXTX; DNA polymerase beta domain protein region; KEGG: scl:sce0152 polynucleotide adenyltransferase; endonuclease/exonuclease/phosphatase 3509063 8327223 Amir_3033 Actinosynnema mirum DSM 43827 endonuclease/exonuclease/phosphatase YP_003100798.1 3506376 D 446462 CDS YP_003100799.1 256377139 8327224 complement(3509072..3509533) 1 NC_013093.1 KEGG: rle:RL3033 hypothetical protein; hypothetical protein 3509533 8327224 Amir_3034 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100799.1 3509072 R 446462 CDS YP_003100800.1 256377140 8327225 complement(3509530..3510099) 1 NC_013093.1 hypothetical protein 3510099 8327225 Amir_3035 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100800.1 3509530 R 446462 CDS YP_003100801.1 256377141 8327226 complement(3510373..3510984) 1 NC_013093.1 PFAM: protein of unknown function DUF162; KEGG: eba:ebA3914 hypothetical protein; hypothetical protein 3510984 8327226 Amir_3036 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100801.1 3510373 R 446462 CDS YP_003100802.1 256377142 8327227 complement(3511476..3512879) 1 NC_013093.1 PFAM: protein of unknown function DUF162; KEGG: rru:Rru_A1412 4Fe-4S ferredoxin, iron-sulfur binding; hypothetical protein 3512879 8327227 Amir_3037 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100802.1 3511476 R 446462 CDS YP_003100803.1 256377143 8327228 complement(3512891..3513631) 1 NC_013093.1 PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: sus:Acid_5763 hypothetical protein; hypothetical protein 3513631 8327228 Amir_3038 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100803.1 3512891 R 446462 CDS YP_003100804.1 256377144 8327229 3513640..3514395 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: scl:sce0751 GntR family transcriptional regulator; GntR family transcriptional regulator 3514395 8327229 Amir_3039 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003100804.1 3513640 D 446462 CDS YP_003100805.1 256377145 8327230 complement(3514866..3515885) 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: ppw:PputW619_1959 LacI family transcription regulator; LacI family transcriptional regulator 3515885 8327230 Amir_3040 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003100805.1 3514866 R 446462 CDS YP_003100806.1 256377146 8327231 3516064..3517566 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bph:Bphy_3463 ABC transporter; ABC transporter 3517566 8327231 Amir_3041 Actinosynnema mirum DSM 43827 ABC transporter YP_003100806.1 3516064 D 446462 CDS YP_003100807.1 256377147 8327232 3517563..3518585 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: bac:BamMC406_1213 monosaccharide-transporting ATPase; Monosaccharide-transporting ATPase 3518585 8327232 Amir_3042 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003100807.1 3517563 D 446462 CDS YP_003100808.1 256377148 8327233 3518575..3519564 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: bxe:Bxe_B1037 ABC sugar transporter, inner membrane subunit; Monosaccharide-transporting ATPase 3519564 8327233 Amir_3043 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003100808.1 3518575 D 446462 CDS YP_003100809.1 256377149 8327234 3519594..3520670 1 NC_013093.1 TIGRFAM: rhamnose ABC transporter, periplasmic rhamnose-binding protein; KEGG: bph:Bphy_3460 rhamnose ABC transporter, periplasmic rhamnose-binding protein; rhamnose ABC transporter periplasmic rhamnose- binding protein 3520670 8327234 Amir_3044 Actinosynnema mirum DSM 43827 rhamnose ABC transporter periplasmic rhamnose- binding protein YP_003100809.1 3519594 D 446462 CDS YP_003100810.1 256377150 8327235 3520733..3521923 1 NC_013093.1 TIGRFAM: L-rhamnose isomerase; PFAM: xylose isomerase; KEGG: acr:Acry_2987 L-rhamnose isomerase; L-rhamnose isomerase 3521923 8327235 Amir_3045 Actinosynnema mirum DSM 43827 L-rhamnose isomerase YP_003100810.1 3520733 D 446462 CDS YP_003100811.1 256377151 8327236 3521926..3523956 1 NC_013093.1 TIGRFAM: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; PFAM: class II aldolase/adducin family protein; KR domain protein; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: rde:RD1_3083 short chain dehydrogenase; short chain dehydrogenase 3523956 8327236 Amir_3046 Actinosynnema mirum DSM 43827 short chain dehydrogenase YP_003100811.1 3521926 D 446462 CDS YP_003100812.1 256377152 8327237 3523969..3525375 1 NC_013093.1 PFAM: carbohydrate kinase FGGY; KEGG: sus:Acid_3424 carbohydrate kinase, FGGY; carbohydrate kinase FGGY 3525375 8327237 Amir_3047 Actinosynnema mirum DSM 43827 carbohydrate kinase FGGY YP_003100812.1 3523969 D 446462 CDS YP_003100813.1 256377153 8327238 3525392..3525721 1 NC_013093.1 KEGG: smt:Smal_1180 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 3525721 8327238 Amir_3048 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003100813.1 3525392 D 446462 CDS YP_003100814.1 256377154 8327239 complement(3525753..3526997) 1 NC_013093.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: azc:AZC_1412 hypothetical protein; amidohydrolase 3526997 8327239 Amir_3049 Actinosynnema mirum DSM 43827 amidohydrolase YP_003100814.1 3525753 R 446462 CDS YP_003100815.1 256377155 8327240 complement(3527106..3527465) 1 NC_013093.1 KEGG: mpo:Mpop_1143 hypothetical protein; hypothetical protein 3527465 8327240 Amir_3050 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100815.1 3527106 R 446462 CDS YP_003100816.1 256377156 8327241 3527537..3528394 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: smt:Smal_0276 transcriptional regulator, LysR family; LysR family transcriptional regulator 3528394 8327241 Amir_3051 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003100816.1 3527537 D 446462 CDS YP_003100817.1 256377157 8327244 complement(3529055..3530221) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3530221 8327244 Amir_3054 Actinosynnema mirum DSM 43827 histidine kinase YP_003100817.1 3529055 R 446462 CDS YP_003100818.1 256377158 8327245 complement(3530167..3530736) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mlo:mlr3851 TetR family transcriptional regulator; TetR family transcriptional regulator 3530736 8327245 Amir_3055 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100818.1 3530167 R 446462 CDS YP_003100819.1 256377159 8327246 complement(3530770..3532854) 1 NC_013093.1 KEGG: hypothetical protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; ECF subfamily RNA polymerase sigma-24 subunit 3532854 8327246 Amir_3056 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003100819.1 3530770 R 446462 CDS YP_003100820.1 256377160 8327247 complement(3533317..3533655) 1 NC_013093.1 KEGG: ses:SARI_03963 hypothetical protein; hypothetical protein 3533655 8327247 Amir_3057 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100820.1 3533317 R 446462 CDS YP_003100821.1 256377161 8327248 complement(3533662..3534024) 1 NC_013093.1 PFAM: protein of unknown function DUF202; KEGG: pmy:Pmen_1718 hypothetical protein; hypothetical protein 3534024 8327248 Amir_3058 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100821.1 3533662 R 446462 CDS YP_003100822.1 256377162 8327249 complement(3534131..3535384) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: mlo:mll6125 cytochrome P450-family protein; cytochrome P450 3535384 8327249 Amir_3059 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100822.1 3534131 R 446462 CDS YP_003100823.1 256377163 8327250 complement(3535635..3536576) 1 NC_013093.1 SMART: regulatory protein ArsR; KEGG: ade:Adeh_4096 serine/threonine protein kinase; ArsR family transcriptional regulator 3536576 8327250 Amir_3060 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003100823.1 3535635 R 446462 CDS YP_003100824.1 256377164 8327251 3536831..3537214 1 NC_013093.1 hypothetical protein 3537214 8327251 Amir_3061 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100824.1 3536831 D 446462 CDS YP_003100825.1 256377165 8327252 complement(3537339..3537992) 1 NC_013093.1 PFAM: Haem oxygenase-like; KEGG: rpa:RPA1539 heme oxygenase (decyclizing); Heme oxygenase 3537992 8327252 Amir_3062 Actinosynnema mirum DSM 43827 Heme oxygenase YP_003100825.1 3537339 R 446462 CDS YP_003100826.1 256377166 8327253 3538184..3539098 1 NC_013093.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bha:BH2806 carboxylesterase; alpha/beta hydrolase fold-3 domain-containing protein 3539098 8327253 Amir_3063 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold-3 domain-containing protein YP_003100826.1 3538184 D 446462 CDS YP_003100827.1 256377167 8327255 3540076..3540864 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: bcb:BCB4264_A2458 hypothetical protein; G-D-S-L family lipolytic protein 3540864 8327255 Amir_3065 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003100827.1 3540076 D 446462 CDS YP_003100828.1 256377168 8327256 3540979..3542622 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: dde:Dde_1329 dipeptide ABC transporter, solute-binding protein; family 5 extracellular solute-binding protein 3542622 8327256 Amir_3066 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003100828.1 3540979 D 446462 CDS YP_003100829.1 256377169 8327257 3542616..3543728 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dde:Dde_1328 dipeptide ABC transporter, permease protein; ABC transporter inner membrane protein 3543728 8327257 Amir_3067 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100829.1 3542616 D 446462 CDS YP_003100830.1 256377170 8327258 3543725..3544555 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dde:Dde_1327 dipeptide ABC transporter, permease protein; ABC transporter inner membrane protein 3544555 8327258 Amir_3068 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003100830.1 3543725 D 446462 CDS YP_003100831.1 256377171 8327259 3544552..3545361 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: dde:Dde_1326 ATPase; ABC transporter 3545361 8327259 Amir_3069 Actinosynnema mirum DSM 43827 ABC transporter YP_003100831.1 3544552 D 446462 CDS YP_003100832.1 256377172 8327260 3545358..3545996 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: dde:Dde_1325 ATPase; ABC transporter 3545996 8327260 Amir_3070 Actinosynnema mirum DSM 43827 ABC transporter YP_003100832.1 3545358 D 446462 CDS YP_003100833.1 256377173 8327261 3546155..3547993 1 NC_013093.1 KEGG: scl:sce4939 hypothetical protein; TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; asparagine synthase 3547993 8327261 Amir_3071 Actinosynnema mirum DSM 43827 asparagine synthase YP_003100833.1 3546155 D 446462 CDS YP_003100834.1 256377174 8327262 3548265..3548585 1 NC_013093.1 hypothetical protein 3548585 8327262 Amir_3072 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100834.1 3548265 D 446462 CDS YP_003100835.1 256377175 8327263 3548582..3550843 1 NC_013093.1 KEGG: mgm:Mmc1_2162 hypothetical protein; hypothetical protein 3550843 8327263 Amir_3073 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100835.1 3548582 D 446462 CDS YP_003100836.1 256377176 8327264 complement(3550985..3551314) 1 NC_013093.1 PFAM: small multidrug resistance protein; KEGG: acr:Acry_0986 small multidrug resistance protein; small multidrug resistance protein 3551314 8327264 Amir_3074 Actinosynnema mirum DSM 43827 small multidrug resistance protein YP_003100836.1 3550985 R 446462 CDS YP_003100837.1 256377177 8327265 complement(3551551..3552864) 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: rsq:Rsph17025_3685 hypothetical protein; class III aminotransferase 3552864 8327265 Amir_3075 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003100837.1 3551551 R 446462 CDS YP_003100838.1 256377178 8327266 complement(3552861..3554159) 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: aba:Acid345_3989 4-aminobutyrate aminotransferase; acetylornithine transaminase 3554159 8327266 Amir_3076 Actinosynnema mirum DSM 43827 acetylornithine transaminase YP_003100838.1 3552861 R 446462 CDS YP_003100839.1 256377179 8327267 complement(3554156..3555721) 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: sfu:Sfum_2203 aldehyde dehydrogenase; aldehyde dehydrogenase 3555721 8327267 Amir_3077 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003100839.1 3554156 R 446462 CDS YP_003100840.1 256377180 8327268 3556274..3558508 1 NC_013093.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 3558508 8327268 Amir_3078 Actinosynnema mirum DSM 43827 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_003100840.1 3556274 D 446462 CDS YP_003100841.1 256377181 8327269 3558964..3560028 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: mxa:MXAN_2296 O-methyltransferase family protein; O-methyltransferase 3560028 8327269 Amir_3079 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003100841.1 3558964 D 446462 CDS YP_003100842.1 256377182 8327270 3560165..3561487 1 NC_013093.1 PFAM: beta-lactamase; KEGG: aba:Acid345_4043 beta-lactamase; beta-lactamase 3561487 8327270 Amir_3080 Actinosynnema mirum DSM 43827 beta-lactamase YP_003100842.1 3560165 D 446462 CDS YP_003100843.1 256377183 8327271 complement(3561549..3562364) 1 NC_013093.1 hypothetical protein 3562364 8327271 Amir_3081 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100843.1 3561549 R 446462 CDS YP_003100844.1 256377184 8327272 complement(3562364..3563494) 1 NC_013093.1 KEGG: mex:Mext_2409 hypothetical protein; hypothetical protein 3563494 8327272 Amir_3082 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100844.1 3562364 R 446462 CDS YP_003100845.1 256377185 8327273 complement(3563494..3563829) 1 NC_013093.1 hypothetical protein 3563829 8327273 Amir_3083 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100845.1 3563494 R 446462 CDS YP_003100846.1 256377186 8327274 complement(3563867..3564520) 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: ade:Adeh_0726 hypothetical protein; hypothetical protein 3564520 8327274 Amir_3084 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100846.1 3563867 R 446462 CDS YP_003100847.1 256377187 8327276 complement(3565933..3566313) 1 NC_013093.1 KEGG: mrd:Mrad2831_6137 transposase; transposase 3566313 8327276 Amir_3086 Actinosynnema mirum DSM 43827 transposase YP_003100847.1 3565933 R 446462 CDS YP_003100848.1 256377188 8327277 complement(3566472..3566894) 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: mms:mma_1646 hypothetical protein; endoribonuclease L-PSP 3566894 8327277 Amir_3087 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003100848.1 3566472 R 446462 CDS YP_003100849.1 256377189 8327278 3567005..3567547 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rso:RSc2325 transcription regulator protein; MarR family transcriptional regulator 3567547 8327278 Amir_3088 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003100849.1 3567005 D 446462 CDS YP_003100850.1 256377190 8327279 3567656..3569236 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 3569236 8327279 Amir_3089 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003100850.1 3567656 D 446462 CDS YP_003100851.1 256377191 8327280 complement(3569331..3570182) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpe:KPK_2589 transcriptional regulator, LysR family; LysR family transcriptional regulator 3570182 8327280 Amir_3090 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003100851.1 3569331 R 446462 CDS YP_003100852.1 256377192 8327281 3570227..3571156 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: hypothetical protein; hypothetical protein 3571156 8327281 Amir_3091 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100852.1 3570227 D 446462 CDS YP_003100853.1 256377193 8327282 3571222..3572085 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 3572085 8327282 Amir_3092 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003100853.1 3571222 D 446462 CDS YP_003100854.1 256377194 8327283 3572224..3573423 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bmv:BMASAVP1_A0386 transporter; major facilitator superfamily protein 3573423 8327283 Amir_3093 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003100854.1 3572224 D 446462 CDS YP_003100855.1 256377195 8327285 complement(3573679..3573954) 1 NC_013093.1 hypothetical protein 3573954 8327285 Amir_3095 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100855.1 3573679 R 446462 CDS YP_003100856.1 256377196 8327286 3574068..3574433 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: dal:Dalk_3679 transcriptional regulator, ArsR family; ArsR family transcriptional regulator 3574433 8327286 Amir_3096 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003100856.1 3574068 D 446462 CDS YP_003100857.1 256377197 8327287 3574437..3576449 1 NC_013093.1 TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: afe:Lferr_0209 heavy metal translocating P- type ATPase; heavy metal translocating P-type ATPase 3576449 8327287 Amir_3097 Actinosynnema mirum DSM 43827 heavy metal translocating P-type ATPase YP_003100857.1 3574437 D 446462 CDS YP_003100858.1 256377198 8327288 complement(3576475..3577119) 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: aba:Acid345_3929 HAD-superfamily hydrolase subfamily IA, variant 3; HAD superfamily hydrolase 3577119 8327288 Amir_3098 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003100858.1 3576475 R 446462 CDS YP_003100859.1 256377199 8327289 3577184..3578341 1 NC_013093.1 PFAM: ROK family protein; KEGG: sme:SMa2303 ROK family transcriptional regulator; ROK family protein 3578341 8327289 Amir_3099 Actinosynnema mirum DSM 43827 ROK family protein YP_003100859.1 3577184 D 446462 CDS YP_003100860.1 256377200 8327290 complement(3578325..3579053) 1 NC_013093.1 hypothetical protein 3579053 8327290 Amir_3100 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100860.1 3578325 R 446462 CDS YP_003100861.1 256377201 8327291 complement(3579050..3580798) 1 NC_013093.1 KEGG: ade:Adeh_0992 Vgr-related protein; hypothetical protein 3580798 8327291 Amir_3101 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100861.1 3579050 R 446462 CDS YP_003100862.1 256377202 8327292 complement(3580955..3582430) 1 NC_013093.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 3582430 8327292 Amir_3102 Actinosynnema mirum DSM 43827 S-adenosyl-L-homocysteine hydrolase YP_003100862.1 3580955 R 446462 CDS YP_003100863.1 256377203 8327293 complement(3582456..3583661) 1 NC_013093.1 KEGG: bha:BH3300 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 3583661 8327293 Amir_3103 Actinosynnema mirum DSM 43827 S-adenosylmethionine synthetase YP_003100863.1 3582456 R 446462 CDS YP_003100864.1 256377204 8327294 3583893..3585032 1 NC_013093.1 KEGG: dal:Dalk_4624 hypothetical protein; hypothetical protein 3585032 8327294 Amir_3104 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100864.1 3583893 D 446462 CDS YP_003100865.1 256377205 8327295 complement(3585039..3585503) 1 NC_013093.1 hypothetical protein 3585503 8327295 Amir_3105 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100865.1 3585039 R 446462 CDS YP_003100866.1 256377206 8327296 complement(3585645..3587291) 1 NC_013093.1 PFAM: Ricin B lectin; glycoside hydrolase clan GH- D; SMART: Ricin B lectin; KEGG: cak:Caul_2129 alpha-galactosidase; Ricin B lectin 3587291 8327296 Amir_3106 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003100866.1 3585645 R 446462 CDS YP_003100867.1 256377207 8327297 3587729..3590044 1 NC_013093.1 PFAM: protein of unknown function DUF1680; Ricin B lectin; KEGG: hypothetical protein; hypothetical protein 3590044 8327297 Amir_3107 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100867.1 3587729 D 446462 CDS YP_003100868.1 256377208 8327298 3590424..3591530 1 NC_013093.1 PFAM: Ricin B lectin; lipolytic protein G-D-S-L family; SMART: Ricin B lectin; KEGG: hypothetical protein; Ricin B lectin 3591530 8327298 Amir_3108 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003100868.1 3590424 D 446462 CDS YP_003100869.1 256377209 8327299 3591766..3593100 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: eta:ETA_13590 flavoprotein monooxygenase; FAD-binding monooxygenase 3593100 8327299 Amir_3109 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003100869.1 3591766 D 446462 CDS YP_003100870.1 256377210 8327300 3593097..3594698 1 NC_013093.1 PFAM: aminotransferase class I and II; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mxa:MXAN_2571 aminotransferase, class II; class I and II aminotransferase 3594698 8327300 Amir_3110 Actinosynnema mirum DSM 43827 class I and II aminotransferase YP_003100870.1 3593097 D 446462 CDS YP_003100871.1 256377211 8327301 complement(3594753..3595643) 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: bav:BAV1824 transcriptional regulator; AsnC family transcriptional regulator 3595643 8327301 Amir_3111 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003100871.1 3594753 R 446462 CDS YP_003100872.1 256377212 8327302 complement(3595640..3596596) 1 NC_013093.1 KEGG: similar to ODAG protein; hypothetical protein 3596596 8327302 Amir_3112 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100872.1 3595640 R 446462 CDS YP_003100873.1 256377213 8327303 complement(3596668..3598617) 1 NC_013093.1 KEGG: xcb:XC_2636 plasmid-related protein; plasmid-like protein 3598617 8327303 Amir_3113 Actinosynnema mirum DSM 43827 plasmid-like protein YP_003100873.1 3596668 R 446462 CDS YP_003100874.1 256377214 8327304 complement(3598614..3599102) 1 NC_013093.1 KEGG: bps:BPSL0769 hypothetical protein; hypothetical protein 3599102 8327304 Amir_3114 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100874.1 3598614 R 446462 CDS YP_003100875.1 256377215 8327305 complement(3599099..3600310) 1 NC_013093.1 KEGG: xcb:XC_2635 hypothetical protein; hypothetical protein 3600310 8327305 Amir_3115 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100875.1 3599099 R 446462 CDS YP_003100876.1 256377216 8327306 3600866..3602050 1 NC_013093.1 hypothetical protein 3602050 8327306 Amir_3116 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100876.1 3600866 D 446462 CDS YP_003100877.1 256377217 8327307 complement(3602172..3602786) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: dol:Dole_0928 TetR family transcriptional regulator; TetR family transcriptional regulator 3602786 8327307 Amir_3117 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100877.1 3602172 R 446462 CDS YP_003100878.1 256377218 8327308 3602876..3603745 1 NC_013093.1 PFAM: NmrA family protein; dTDP-4-dehydrorhamnose reductase; KEGG: mlo:mlr0239 hypothetical protein; NmrA family protein 3603745 8327308 Amir_3118 Actinosynnema mirum DSM 43827 NmrA family protein YP_003100878.1 3602876 D 446462 CDS YP_003100879.1 256377219 8327309 3603742..3604641 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: swi:Swit_2098 luciferase family protein; luciferase-like monooxygenase 3604641 8327309 Amir_3119 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003100879.1 3603742 D 446462 CDS YP_003100880.1 256377220 8327311 3605268..3606515 1 NC_013093.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: xau:Xaut_2796 cyclic nucleotide-binding protein; protein serine/threonine phosphatase 3606515 8327311 Amir_3121 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003100880.1 3605268 D 446462 CDS YP_003100881.1 256377221 8327312 3607014..3607250 1 NC_013093.1 hypothetical protein 3607250 8327312 Amir_3122 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100881.1 3607014 D 446462 CDS YP_003100882.1 256377222 8327313 3607447..3611625 1 NC_013093.1 KEGG: mxa:MXAN_5493 WD domain G-beta repeat protein; hypothetical protein 3611625 8327313 Amir_3123 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100882.1 3607447 D 446462 CDS YP_003100883.1 256377223 8327314 complement(3611656..3612777) 1 NC_013093.1 KEGG: hne:HNE_0890 TRAP dicarboxylate transporter, DctM subunit; hypothetical protein 3612777 8327314 Amir_3124 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100883.1 3611656 R 446462 CDS YP_003100884.1 256377224 8327315 complement(3613022..3613303) 1 NC_013093.1 KEGG: mxa:MXAN_6144 oxygen-dependent FAD- linked oxidoreductase; hypothetical protein 3613303 8327315 Amir_3125 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100884.1 3613022 R 446462 CDS YP_003100885.1 256377225 8327316 complement(3613444..3613887) 1 NC_013093.1 PFAM: FAD linked oxidase domain protein; KEGG: mxa:MXAN_6144 oxygen-dependent FAD- linked oxidoreductase; FAD linked oxidase domain-containing protein 3613887 8327316 Amir_3126 Actinosynnema mirum DSM 43827 FAD linked oxidase domain-containing protein YP_003100885.1 3613444 R 446462 CDS YP_003100886.1 256377226 8327318 complement(3614844..3615773) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: scl:sce1114 LysR family transcriptional regulator; LysR family transcriptional regulator 3615773 8327318 Amir_3128 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003100886.1 3614844 R 446462 CDS YP_003100887.1 256377227 8327319 3615819..3616556 1 NC_013093.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; KEGG: scl:sce8821 hypothetical protein; FAD-binding 9 siderophore-interacting domain-containing protein 3616556 8327319 Amir_3129 Actinosynnema mirum DSM 43827 FAD-binding 9 siderophore-interacting domain-containing protein YP_003100887.1 3615819 D 446462 CDS YP_003100888.1 256377228 8327320 3616830..3617096 1 NC_013093.1 KEGG: dal:Dalk_3308 acyl carrier protein; hypothetical protein 3617096 8327320 Amir_3130 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100888.1 3616830 D 446462 CDS YP_003100889.1 256377229 8327321 3617096..3618061 1 NC_013093.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier- protein (ACP)] synthase III; KEGG: gdi:GDI3075 3-oxoacyl-[acyl-carrier- protein] synthase 3 (3-oxoacyl [acyl-carrier-protein] synthase III) (beta-ketoacyl-ACP synthase III (KAS III); beta-ketoacyl-acyl-carrier-protein synthase I 3618061 8327321 Amir_3131 Actinosynnema mirum DSM 43827 beta-ketoacyl-acyl-carrier-protein synthase I YP_003100889.1 3617096 D 446462 CDS YP_003100890.1 256377230 8327322 3618088..3619422 1 NC_013093.1 PFAM: cytochrome P450; KEGG: mxa:MXAN_3943 cytochrome P450 family protein; cytochrome P450 3619422 8327322 Amir_3132 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100890.1 3618088 D 446462 CDS YP_003100891.1 256377231 8327323 3619419..3620462 1 NC_013093.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: bpy:Bphyt_6246 3-oxoacyl-(acyl-carrier- protein (ACP)) synthase III domain protein; 3-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III domain-containing protein 3620462 8327323 Amir_3133 Actinosynnema mirum DSM 43827 3-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III domain-containing protein YP_003100891.1 3619419 D 446462 CDS YP_003100892.1 256377232 8327324 3620477..3623104 1 NC_013093.1 PFAM: aminotransferase class-III; protein of unknown function RIO1; aminoglycoside phosphotransferase; ABC-1 domain protein; KEGG: sus:Acid_1674 aminotransferase; class III aminotransferase 3623104 8327324 Amir_3134 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003100892.1 3620477 D 446462 CDS YP_003100893.1 256377233 8327325 3623108..3623974 1 NC_013093.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: bur:Bcep18194_C6793 beta-hydroxyacid dehydrogenase; 6-phosphogluconate dehydrogenase 3623974 8327325 Amir_3135 Actinosynnema mirum DSM 43827 6-phosphogluconate dehydrogenase YP_003100893.1 3623108 D 446462 CDS YP_003100894.1 256377234 8327326 complement(3623982..3624347) 1 NC_013093.1 KEGG: mpo:Mpop_0225 hypothetical protein; hypothetical protein 3624347 8327326 Amir_3136 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100894.1 3623982 R 446462 CDS YP_003100895.1 256377235 8327327 complement(3624401..3625156) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: ret:RHE_PE00158 methyltransferase protein; type 11 methyltransferase 3625156 8327327 Amir_3137 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003100895.1 3624401 R 446462 CDS YP_003100896.1 256377236 8327328 3625259..3625699 1 NC_013093.1 hypothetical protein 3625699 8327328 Amir_3138 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100896.1 3625259 D 446462 CDS YP_003100897.1 256377237 8327329 complement(3625742..3626476) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: 3-oxoacyl-(acyl-carrier-protein) reductase protein; K00059 3-oxoacyl-; short-chain dehydrogenase/reductase SDR 3626476 8327329 Amir_3139 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100897.1 3625742 R 446462 CDS YP_003100898.1 256377238 8327330 3626621..3627313 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bid:Bind_1892 TetR family transcriptional regulator; TetR family transcriptional regulator 3627313 8327330 Amir_3140 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100898.1 3626621 D 446462 CDS YP_003100899.1 256377239 8327331 3627477..3628262 1 NC_013093.1 PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: bur:Bcep18194_C6861 fructose-bisphosphate aldolase; deoxyribose-phosphate aldolase/phospho-2-dehydro- 3-deoxyheptonate aldolase 3628262 8327331 Amir_3141 Actinosynnema mirum DSM 43827 deoxyribose-phosphate aldolase/phospho-2-dehydro- 3-deoxyheptonate aldolase YP_003100899.1 3627477 D 446462 CDS YP_003100900.1 256377240 8327332 complement(3628412..3629452) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: reu:Reut_C6082 zinc-containing alcohol dehydrogenase superfamily protein; alcohol dehydrogenase GroES domain-containing protein 3629452 8327332 Amir_3142 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003100900.1 3628412 R 446462 CDS YP_003100901.1 256377241 8327333 complement(3629449..3630141) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce6308 TetR family transcriptional regulator; TetR family transcriptional regulator 3630141 8327333 Amir_3143 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100901.1 3629449 R 446462 CDS YP_003100902.1 256377242 8327334 3630422..3631927 1 NC_013093.1 PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; KEGG: esa:ESA_00979 hypothetical protein; sulfate transporter 3631927 8327334 Amir_3144 Actinosynnema mirum DSM 43827 sulfate transporter YP_003100902.1 3630422 D 446462 CDS YP_003100903.1 256377243 8327335 3632037..3632759 1 NC_013093.1 PFAM: B3/4 domain protein; KEGG: hypothetical protein; B3/4 domain-containing protein 3632759 8327335 Amir_3145 Actinosynnema mirum DSM 43827 B3/4 domain-containing protein YP_003100903.1 3632037 D 446462 CDS YP_003100904.1 256377244 8327336 3632947..3634179 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 3634179 8327336 Amir_3146 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003100904.1 3632947 D 446462 CDS YP_003100905.1 256377245 8327337 complement(3634208..3634759) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bat:BAS4873 transcriptional regulator; TetR family transcriptional regulator 3634759 8327337 Amir_3147 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100905.1 3634208 R 446462 CDS YP_003100906.1 256377246 8327338 complement(3634832..3635521) 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; KEGG: pfo:Pfl01_1835 ThiJ/PfpI; ThiJ/PfpI domain-containing protein 3635521 8327338 Amir_3148 Actinosynnema mirum DSM 43827 ThiJ/PfpI domain-containing protein YP_003100906.1 3634832 R 446462 CDS YP_003100907.1 256377247 8327339 complement(3635559..3636392) 1 NC_013093.1 PFAM: abortive infection protein; KEGG: sdn:Sden_1909 abortive infection protein; abortive infection protein 3636392 8327339 Amir_3149 Actinosynnema mirum DSM 43827 abortive infection protein YP_003100907.1 3635559 R 446462 CDS YP_003100908.1 256377248 8327341 complement(3637126..3638271) 1 NC_013093.1 PFAM: arsenical pump membrane protein; Citrate transporter; KEGG: bvi:Bcep1808_6442 arsenical pump membrane protein; arsenical pump membrane protein 3638271 8327341 Amir_3151 Actinosynnema mirum DSM 43827 arsenical pump membrane protein YP_003100908.1 3637126 R 446462 CDS YP_003100909.1 256377249 8327342 complement(3638268..3639443) 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: rpi:Rpic_2954 metallophosphoesterase; metallophosphoesterase 3639443 8327342 Amir_3152 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003100909.1 3638268 R 446462 CDS YP_003100910.1 256377250 8327343 complement(3639554..3640222) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bid:Bind_0033 TetR family transcriptional regulator; TetR family transcriptional regulator 3640222 8327343 Amir_3153 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100910.1 3639554 R 446462 CDS YP_003100911.1 256377251 8327344 3640512..3641660 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: sde:Sde_3022 hypothetical protein; Ricin B lectin 3641660 8327344 Amir_3154 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003100911.1 3640512 D 446462 CDS YP_003100912.1 256377252 8327345 complement(3641698..3642741) 1 NC_013093.1 hypothetical protein 3642741 8327345 Amir_3155 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100912.1 3641698 R 446462 CDS YP_003100913.1 256377253 8327346 complement(3642738..3643904) 1 NC_013093.1 hypothetical protein 3643904 8327346 Amir_3156 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100913.1 3642738 R 446462 CDS YP_003100914.1 256377254 8327347 3644502..3647354 1 NC_013093.1 KEGG: mes:Meso_2703 ribonucleotide-diphosphate reductase subunit alpha; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit; PFAM: ribonucleotide reductase large subunit; ATP- cone domain protein; ribonucleotide reductase large subunit domain protein; ribonucleoside-diphosphate reductase subunit alpha 3647354 8327347 Amir_3157 Actinosynnema mirum DSM 43827 ribonucleoside-diphosphate reductase subunit alpha YP_003100914.1 3644502 D 446462 CDS YP_003100915.1 256377255 8327348 3647351..3648427 1 NC_013093.1 PFAM: ribonucleotide reductase; KEGG: oca:OCAR_6755 ribonucleoside-diphosphate reductase, beta subunit; ribonucleoside-diphosphate reductase 3648427 8327348 Amir_3158 Actinosynnema mirum DSM 43827 ribonucleoside-diphosphate reductase YP_003100915.1 3647351 D 446462 CDS YP_003100916.1 256377256 8327349 3648629..3649867 1 NC_013093.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: bcb:BCB4264_A1874 transport protein, NRAMP family; Mn2+/Fe2+ transporter, NRAMP family 3649867 8327349 Amir_3159 Actinosynnema mirum DSM 43827 Mn2+/Fe2+ transporter, NRAMP family YP_003100916.1 3648629 D 446462 CDS YP_003100917.1 256377257 8327350 complement(3649919..3651133) 1 NC_013093.1 PFAM: protein of unknown function DUF955; helix- turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ppd:Ppro_0104 helix-turn-helix domain- containing protein; hypothetical protein 3651133 8327350 Amir_3160 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100917.1 3649919 R 446462 CDS YP_003100918.1 256377258 8327351 complement(3651130..3651933) 1 NC_013093.1 hypothetical protein 3651933 8327351 Amir_3161 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100918.1 3651130 R 446462 CDS YP_003100919.1 256377259 8327352 3652133..3654349 1 NC_013093.1 PFAM: MMPL domain protein; KEGG: bsu:BSU05430 hypothetical protein; MMPL domain-containing protein 3654349 8327352 Amir_3162 Actinosynnema mirum DSM 43827 MMPL domain-containing protein YP_003100919.1 3652133 D 446462 CDS YP_003100920.1 256377260 8327353 3654551..3655276 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce8862 BKRF1 encodes EBNA-1 protein, latent cycle gene; G-D-S-L family lipolytic protein 3655276 8327353 Amir_3163 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003100920.1 3654551 D 446462 CDS YP_003100921.1 256377261 8327354 3655388..3655732 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; anti-sigma-factor antagonist 3655732 8327354 Amir_3164 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003100921.1 3655388 D 446462 CDS YP_003100922.1 256377262 8327355 3655954..3656958 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: acr:Acry_0624 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 3656958 8327355 Amir_3165 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003100922.1 3655954 D 446462 CDS YP_003100923.1 256377263 8327356 3657082..3657708 1 NC_013093.1 KEGG: pzu:PHZ_p0176 hypothetical protein; hypothetical protein 3657708 8327356 Amir_3166 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100923.1 3657082 D 446462 CDS YP_003100924.1 256377264 8327357 3657795..3658148 1 NC_013093.1 hypothetical protein 3658148 8327357 Amir_3167 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100924.1 3657795 D 446462 CDS YP_003100925.1 256377265 8327358 complement(3658171..3658398) 1 NC_013093.1 hypothetical protein 3658398 8327358 Amir_3168 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100925.1 3658171 R 446462 CDS YP_003100926.1 256377266 8327359 3658614..3659090 1 NC_013093.1 KEGG: kpn:KPN_01215 ABC transporter membrane protein; hypothetical protein 3659090 8327359 Amir_3169 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100926.1 3658614 D 446462 CDS YP_003100927.1 256377267 8327360 3659220..3659933 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3659933 8327360 Amir_3170 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100927.1 3659220 D 446462 CDS YP_003100928.1 256377268 8327361 complement(3660347..3661228) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: msl:Msil_0872 alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain-containing protein 3661228 8327361 Amir_3171 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003100928.1 3660347 R 446462 CDS YP_003100929.1 256377269 8327362 3661299..3661895 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mrd:Mrad2831_4515 TetR family transcriptional regulator; TetR family transcriptional regulator 3661895 8327362 Amir_3172 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100929.1 3661299 D 446462 CDS YP_003100930.1 256377270 8327363 3662147..3662413 1 NC_013093.1 KEGG: mca:MCA1086 hypothetical protein; hypothetical protein 3662413 8327363 Amir_3173 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100930.1 3662147 D 446462 CDS YP_003100931.1 256377271 8327364 3662457..3664709 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: neu:NE0720 ABC transporter permease/ATP- binding protein; ABC transporter 3664709 8327364 Amir_3174 Actinosynnema mirum DSM 43827 ABC transporter YP_003100931.1 3662457 D 446462 CDS YP_003100932.1 256377272 8327365 3664718..3665968 1 NC_013093.1 PFAM: sodium/hydrogen exchanger; KEGG: mxa:MXAN_0260 cation transporter/universal stress family protein; sodium/hydrogen exchanger 3665968 8327365 Amir_3175 Actinosynnema mirum DSM 43827 sodium/hydrogen exchanger YP_003100932.1 3664718 D 446462 CDS YP_003100933.1 256377273 8327366 complement(3666067..3666642) 1 NC_013093.1 KEGG: cak:Caul_0156 ricin B lectin; hypothetical protein 3666642 8327366 Amir_3176 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100933.1 3666067 R 446462 CDS YP_003100934.1 256377274 8327367 complement(3666886..3667932) 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: mno:Mnod_7639 O-methyltransferase; O-methyltransferase 3667932 8327367 Amir_3177 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003100934.1 3666886 R 446462 CDS YP_003100935.1 256377275 8327368 3668122..3671346 1 NC_013093.1 PFAM: regulatory protein LuxR; hypothetical protein; Bacterio-opsin activator HTH domain protein; SMART: regulatory protein LuxR; KEGG: GK24882 gene product from transcript GK24882- RA; LuxR family transcriptional regulator 3671346 8327368 Amir_3178 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100935.1 3668122 D 446462 CDS YP_003100936.1 256377276 8327369 3671497..3676278 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 3676278 8327369 Amir_3179 Actinosynnema mirum DSM 43827 acyl transferase YP_003100936.1 3671497 D 446462 CDS YP_003100937.1 256377277 8327370 3676288..3686355 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; NAD- dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: met:M446_0170 beta-ketoacyl synthase; acyl transferase 3686355 8327370 Amir_3180 Actinosynnema mirum DSM 43827 acyl transferase YP_003100937.1 3676288 D 446462 CDS YP_003100938.1 256377278 8327371 3686357..3687136 1 NC_013093.1 PFAM: N-acetyltransferase; KEGG: mxa:MXAN_1194 N-acetyltransferase family protein; N-acetyltransferase 3687136 8327371 Amir_3181 Actinosynnema mirum DSM 43827 N-acetyltransferase YP_003100938.1 3686357 D 446462 CDS YP_003100939.1 256377279 8327372 complement(3687233..3688174) 1 NC_013093.1 TIGRFAM: methyltransferase; PFAM: O-methyltransferase; KEGG: bur:Bcep18194_B1573 protein of unknown function Mtu_121; methyltransferase 3688174 8327372 Amir_3182 Actinosynnema mirum DSM 43827 methyltransferase YP_003100939.1 3687233 R 446462 CDS YP_003100940.1 256377280 8327373 complement(3688171..3689706) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: gbe:GbCGDNIH1_1787 hypothetical protein; FAD-binding monooxygenase 3689706 8327373 Amir_3183 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003100940.1 3688171 R 446462 CDS YP_003100941.1 256377281 8327374 complement(3689718..3691043) 1 NC_013093.1 PFAM: tryptophan halogenase; monooxygenase FAD- binding; FAD dependent oxidoreductase; KEGG: scl:sce7303 dehyrogenase; tryptophan halogenase 3691043 8327374 Amir_3184 Actinosynnema mirum DSM 43827 tryptophan halogenase YP_003100941.1 3689718 R 446462 CDS YP_003100942.1 256377282 8327375 3691300..3692295 1 NC_013093.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: bid:Bind_3102 3-hydroxybutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase 3692295 8327375 Amir_3185 Actinosynnema mirum DSM 43827 3-hydroxyacyl-CoA dehydrogenase YP_003100942.1 3691300 D 446462 CDS YP_003100943.1 256377283 8327376 3692292..3692564 1 NC_013093.1 KEGG: gbm:Gbem_0719 hypothetical protein; hypothetical protein 3692564 8327376 Amir_3186 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100943.1 3692292 D 446462 CDS YP_003100944.1 256377284 8327377 3692557..3693672 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: hch:HCH_03452 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 3693672 8327377 Amir_3187 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003100944.1 3692557 D 446462 CDS YP_003100945.1 256377285 8327378 3693786..3695078 1 NC_013093.1 TIGRFAM: FkbH like protein; HAD-superfamily phosphatase, subfamily IIIC; KEGG: nmu:Nmul_A2515 FkbH domain-containing protein; FkbH like protein 3695078 8327378 Amir_3188 Actinosynnema mirum DSM 43827 FkbH like protein YP_003100945.1 3693786 D 446462 CDS YP_003100946.1 256377286 8327379 3695071..3695733 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: rce:RC1_1081 O-methyltransferase; caffeoyl-CoA O-methyltransferase 3695733 8327379 Amir_3189 Actinosynnema mirum DSM 43827 caffeoyl-CoA O-methyltransferase YP_003100946.1 3695071 D 446462 CDS YP_003100947.1 256377287 8327380 3695911..3698670 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: sme:SMa0464 adenylate/guanylate cyclase; transcriptional regulator 3698670 8327380 Amir_3190 Actinosynnema mirum DSM 43827 transcriptional regulator YP_003100947.1 3695911 D 446462 CDS YP_003100948.1 256377288 8327381 3698696..3699832 1 NC_013093.1 PFAM: acyltransferase 3; KEGG: acp:A2cp1_3016 acyltransferase 3; acyltransferase 3 3699832 8327381 Amir_3191 Actinosynnema mirum DSM 43827 acyltransferase 3 YP_003100948.1 3698696 D 446462 CDS YP_003100949.1 256377289 8327382 complement(3699847..3700194) 1 NC_013093.1 PFAM: YCII-related; KEGG: bja:bll6613 hypothetical protein; YCII-like protein 3700194 8327382 Amir_3192 Actinosynnema mirum DSM 43827 YCII-like protein YP_003100949.1 3699847 R 446462 CDS YP_003100950.1 256377290 8327383 3700424..3702436 1 NC_013093.1 PFAM: carbamoyltransferase; KEGG: mlo:mlr6171 nodulation protein NolO; carbamoyltransferase 3702436 8327383 Amir_3193 Actinosynnema mirum DSM 43827 carbamoyltransferase YP_003100950.1 3700424 D 446462 CDS YP_003100951.1 256377291 8327384 3702839..3703204 1 NC_013093.1 hypothetical protein 3703204 8327384 Amir_3194 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100951.1 3702839 D 446462 CDS YP_003100952.1 256377292 8327385 complement(3703523..3703957) 1 NC_013093.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 3703957 8327385 Amir_3195 Actinosynnema mirum DSM 43827 3-dehydroquinate dehydratase YP_003100952.1 3703523 R 446462 CDS YP_003100953.1 256377293 8327386 3704178..3705344 1 NC_013093.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: rpb:RPB_2068 DegT/DnrJ/EryC1/StrS aminotransferase; glutamine--scyllo-inositol transaminase 3705344 8327386 Amir_3196 Actinosynnema mirum DSM 43827 glutamine--scyllo-inositol transaminase YP_003100953.1 3704178 D 446462 CDS YP_003100954.1 256377294 8327387 3705533..3719260 1 NC_013093.1 PFAM: acyl transferase; AMP-dependent synthetase and ligase; beta-ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; KEGG: met:M446_0172 beta-ketoacyl synthase; acyl transferase 3719260 8327387 Amir_3197 Actinosynnema mirum DSM 43827 acyl transferase YP_003100954.1 3705533 D 446462 CDS YP_003100955.1 256377295 8327388 3719257..3728703 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 3728703 8327388 Amir_3198 Actinosynnema mirum DSM 43827 acyl transferase YP_003100955.1 3719257 D 446462 CDS YP_003100956.1 256377296 8327389 3728780..3729988 1 NC_013093.1 PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; KEGG: cak:Caul_2842 glycosyl transferase family protein; UDP-glucuronosyl/UDP-glucosyltransferase 3729988 8327389 Amir_3199 Actinosynnema mirum DSM 43827 UDP-glucuronosyl/UDP-glucosyltransferase YP_003100956.1 3728780 D 446462 CDS YP_003100957.1 256377297 8327390 3730371..3731396 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ank:AnaeK_2751 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3731396 8327390 Amir_3200 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100957.1 3730371 D 446462 CDS YP_003100958.1 256377298 8327391 complement(3731475..3731939) 1 NC_013093.1 KEGG: sde:Sde_2765 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 3731939 8327391 Amir_3201 Actinosynnema mirum DSM 43827 TonB-dependent siderophore receptor YP_003100958.1 3731475 R 446462 CDS YP_003100959.1 256377299 8327392 complement(3732121..3732702) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bur:Bcep18194_C6787 TetR family transcriptional regulator; TetR family transcriptional regulator 3732702 8327392 Amir_3202 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100959.1 3732121 R 446462 CDS YP_003100960.1 256377300 8327394 complement(3734701..3735750) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 4 domain protein; KEGG: bha:BH1376 RNA polymerase sigma factor RpoD; RpoD subfamily RNA polymerase sigma-70 subunit 3735750 8327394 Amir_3204 Actinosynnema mirum DSM 43827 RpoD subfamily RNA polymerase sigma-70 subunit YP_003100960.1 3734701 R 446462 CDS YP_003100961.1 256377301 8327395 complement(3735915..3736547) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: sil:SPO3211 hypothetical protein; type 11 methyltransferase 3736547 8327395 Amir_3205 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003100961.1 3735915 R 446462 CDS YP_003100962.1 256377302 8327397 complement(3737416..3737991) 1 NC_013093.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: mxa:MXAN_1250 RibD domain protein; bifunctional deaminase-reductase domain-containing protein 3737991 8327397 Amir_3207 Actinosynnema mirum DSM 43827 bifunctional deaminase-reductase domain-containing protein YP_003100962.1 3737416 R 446462 CDS YP_003100963.1 256377303 8327398 3738078..3738692 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: psa:PST_0620 hypothetical protein; TetR family transcriptional regulator 3738692 8327398 Amir_3208 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003100963.1 3738078 D 446462 CDS YP_003100964.1 256377304 8327399 complement(3738944..3740629) 1 NC_013093.1 KEGG: scl:sce8854 secreted protein; hypothetical protein 3740629 8327399 Amir_3209 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100964.1 3738944 R 446462 CDS YP_003100965.1 256377305 8327401 complement(3741439..3742545) 1 NC_013093.1 KEGG: rce:RC1_3059 hypothetical protein; hypothetical protein 3742545 8327401 Amir_3211 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100965.1 3741439 R 446462 CDS YP_003100966.1 256377306 8327402 complement(3742622..3743374) 1 NC_013093.1 PFAM: intradiol ring-cleavage dioxygenase; KEGG: noc:Noc_1128 protocatechuate 3 4-dioxygenase beta subunit like protein; intradiol ring-cleavage dioxygenase 3743374 8327402 Amir_3212 Actinosynnema mirum DSM 43827 intradiol ring-cleavage dioxygenase YP_003100966.1 3742622 R 446462 CDS YP_003100967.1 256377307 8327403 complement(3743552..3744946) 1 NC_013093.1 PFAM: glycoside hydrolase family 43; carbohydrate binding family 6; SMART: cellulose binding type IV; KEGG: hypothetical protein; glycoside hydrolase family protein 3744946 8327403 Amir_3213 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003100967.1 3743552 R 446462 CDS YP_003100968.1 256377308 8327404 complement(3744954..3746327) 1 NC_013093.1 KEGG: XylD; endoxylanase D; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase 3746327 8327404 Amir_3214 Actinosynnema mirum DSM 43827 endo-1,4-beta-xylanase YP_003100968.1 3744954 R 446462 CDS YP_003100969.1 256377309 8327405 3746657..3747973 1 NC_013093.1 PFAM: glycoside hydrolase family 6; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: mxa:MXAN_4837 endoglucanase; glycoside hydrolase family protein 3747973 8327405 Amir_3215 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003100969.1 3746657 D 446462 CDS YP_003100970.1 256377310 8327406 3748226..3750175 1 NC_013093.1 PFAM: glycoside hydrolase family 5; Fibronectin type III domain protein; cellulose-binding family II; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: azc:AZC_1301 endoglucanase; glycoside hydrolase family protein 3750175 8327406 Amir_3216 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003100970.1 3748226 D 446462 CDS YP_003100971.1 256377311 8327407 complement(3750230..3750451) 1 NC_013093.1 PFAM: proteinase inhibitor I13 potato inhibitor I; KEGG: similar to chymotrypsin inhibitor 2; proteinase inhibitor I13 potato inhibitor I 3750451 8327407 Amir_3217 Actinosynnema mirum DSM 43827 proteinase inhibitor I13 potato inhibitor I YP_003100971.1 3750230 R 446462 CDS YP_003100972.1 256377312 8327408 3750581..3751756 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3751756 8327408 Amir_3218 Actinosynnema mirum DSM 43827 histidine kinase YP_003100972.1 3750581 D 446462 CDS YP_003100973.1 256377313 8327409 3751753..3752379 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 3752379 8327409 Amir_3219 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003100973.1 3751753 D 446462 CDS YP_003100974.1 256377314 8327410 3752670..3753290 1 NC_013093.1 KEGG: pap:PSPA7_2550 hypothetical protein; hypothetical protein 3753290 8327410 Amir_3220 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100974.1 3752670 D 446462 CDS YP_003100975.1 256377315 8327411 3753287..3754132 1 NC_013093.1 KEGG: rde:RD1_3606 hypothetical protein; hypothetical protein 3754132 8327411 Amir_3221 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100975.1 3753287 D 446462 CDS YP_003100976.1 256377316 8327412 3754123..3756144 1 NC_013093.1 PFAM: cellulose-binding family II; Spore coat protein CotH; SMART: cellulose-binding family II; KEGG: scl:sce0771 hypothetical protein; cellulose-binding family protein 3756144 8327412 Amir_3222 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003100976.1 3754123 D 446462 CDS YP_003100977.1 256377317 8327413 3756492..3757043 1 NC_013093.1 PFAM: VanZ family protein; VanZ family protein 3757043 8327413 Amir_3223 Actinosynnema mirum DSM 43827 VanZ family protein YP_003100977.1 3756492 D 446462 CDS YP_003100978.1 256377318 8327414 3757040..3758176 1 NC_013093.1 KEGG: hne:HNE_2077 hypothetical protein; hypothetical protein 3758176 8327414 Amir_3224 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100978.1 3757040 D 446462 CDS YP_003100979.1 256377319 8327415 complement(3758191..3758913) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bpy:Bphyt_6660 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3758913 8327415 Amir_3225 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003100979.1 3758191 R 446462 CDS YP_003100980.1 256377320 8327416 complement(3758910..3759947) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: spe:Spro_1178 aldo/keto reductase; aldo/keto reductase 3759947 8327416 Amir_3226 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003100980.1 3758910 R 446462 CDS YP_003100981.1 256377321 8327417 3760068..3760901 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: sml:Smlt2229 hypothetical protein; helix-turn-helix domain-containing protein 3760901 8327417 Amir_3227 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003100981.1 3760068 D 446462 CDS YP_003100982.1 256377322 8327418 complement(3760957..3763521) 1 NC_013093.1 PFAM: Osmosensitive K channel His kinase sensor; ATP-binding region ATPase domain protein; UspA domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mno:Mnod_0197 osmosensitive K+ channel signal transduction histidine kinase; Osmosensitive K channel His kinase sensor 3763521 8327418 Amir_3228 Actinosynnema mirum DSM 43827 Osmosensitive K channel His kinase sensor YP_003100982.1 3760957 R 446462 CDS YP_003100983.1 256377323 8327419 complement(3763595..3764146) 1 NC_013093.1 PFAM: K transporting ATPase KdpC subunit; KEGG: xop:PXO_04385 K+-transporting ATPase, C subunit; Potassium-transporting ATPase 3764146 8327419 Amir_3229 Actinosynnema mirum DSM 43827 Potassium-transporting ATPase YP_003100983.1 3763595 R 446462 CDS YP_003100984.1 256377324 8327420 complement(3764143..3766185) 1 NC_013093.1 TIGRFAM: K+-transporting ATPase, B subunit; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: sus:Acid_0074 K+-transporting ATPase, B subunit; K+-transporting ATPase subunit B 3766185 8327420 Amir_3230 Actinosynnema mirum DSM 43827 K+-transporting ATPase subunit B YP_003100984.1 3764143 R 446462 CDS YP_003100985.1 256377325 8327421 complement(3766182..3767804) 1 NC_013093.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 3767804 8327421 Amir_3231 Actinosynnema mirum DSM 43827 potassium-transporting ATPase subunit A YP_003100985.1 3766182 R 446462 CDS YP_003100986.1 256377326 8327422 complement(3767804..3767905) 1 NC_013093.1 TIGRFAM: K+-transporting ATPase, F subunit; K+-transporting ATPase subunit F 3767905 8327422 Amir_3232 Actinosynnema mirum DSM 43827 K+-transporting ATPase subunit F YP_003100986.1 3767804 R 446462 CDS YP_003100987.1 256377327 8327423 complement(3768790..3770775) 1 NC_013093.1 KEGG: sus:Acid_1791 amino acid transporter; amino acid transporter 3770775 8327423 Amir_3233 Actinosynnema mirum DSM 43827 amino acid transporter YP_003100987.1 3768790 R 446462 CDS YP_003100988.1 256377328 8327424 3771068..3772381 1 NC_013093.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: bcy:Bcer98_1141 diaminopimelate decarboxylase; diaminopimelate decarboxylase 3772381 8327424 Amir_3234 Actinosynnema mirum DSM 43827 diaminopimelate decarboxylase YP_003100988.1 3771068 D 446462 CDS YP_003100989.1 256377329 8327426 complement(3772998..3773411) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: ade:Adeh_0021 periplasmic sensor signal transduction histidine kinase; anti-sigma regulatory factor, serine/threonine protein kinase 3773411 8327426 Amir_3236 Actinosynnema mirum DSM 43827 anti-sigma regulatory factor, serine/threonine protein kinase YP_003100989.1 3772998 R 446462 CDS YP_003100990.1 256377330 8327427 complement(3773780..3774166) 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sfu:Sfum_4033 anti-sigma-factor antagonist; anti-sigma-factor antagonist 3774166 8327427 Amir_3237 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003100990.1 3773780 R 446462 CDS YP_003100991.1 256377331 8327428 3774353..3774949 1 NC_013093.1 KEGG: jan:Jann_4076 secreted protein; hypothetical protein 3774949 8327428 Amir_3238 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100991.1 3774353 D 446462 CDS YP_003100992.1 256377332 8327429 complement(3774980..3775990) 1 NC_013093.1 PFAM: protein of unknown function DUF218; KEGG: bat:BAS4694 hypothetical protein; hypothetical protein 3775990 8327429 Amir_3239 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100992.1 3774980 R 446462 CDS YP_003100993.1 256377333 8327430 3776444..3778192 1 NC_013093.1 PFAM: Recombinase; KEGG: bca:BCE_4599 DNA recombinase; Recombinase 3778192 8327430 Amir_3240 Actinosynnema mirum DSM 43827 Recombinase YP_003100993.1 3776444 D 446462 CDS YP_003100994.1 256377334 8327431 complement(3778260..3778451) 1 NC_013093.1 hypothetical protein 3778451 8327431 Amir_3241 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100994.1 3778260 R 446462 CDS YP_003100995.1 256377335 8327432 complement(3778481..3779083) 1 NC_013093.1 hypothetical protein 3779083 8327432 Amir_3242 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100995.1 3778481 R 446462 CDS YP_003100996.1 256377336 8327433 complement(3779245..3779502) 1 NC_013093.1 hypothetical protein 3779502 8327433 Amir_3243 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100996.1 3779245 R 446462 CDS YP_003100997.1 256377337 8327434 complement(3779653..3780615) 1 NC_013093.1 PFAM: glycoside hydrolase family 25; peptidoglycan- binding LysM; SMART: peptidoglycan-binding LysM; glycoside hydrolase family 25; KEGG: mxa:MXAN_7387 chitinase, class I; glycoside hydrolase family protein 3780615 8327434 Amir_3244 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003100997.1 3779653 R 446462 CDS YP_003100998.1 256377338 8327435 complement(3780695..3781039) 1 NC_013093.1 KEGG: ade:Adeh_2705 response regulator receiver; hypothetical protein 3781039 8327435 Amir_3245 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100998.1 3780695 R 446462 CDS YP_003100999.1 256377339 8327436 complement(3781466..3783685) 1 NC_013093.1 KEGG: rso:RS05070 hemagglutinin/hemolysin- related protein; hypothetical protein 3783685 8327436 Amir_3246 Actinosynnema mirum DSM 43827 hypothetical protein YP_003100999.1 3781466 R 446462 CDS YP_003101000.1 256377340 8327437 complement(3783672..3784466) 1 NC_013093.1 hypothetical protein 3784466 8327437 Amir_3247 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101000.1 3783672 R 446462 CDS YP_003101001.1 256377341 8327438 complement(3784471..3785427) 1 NC_013093.1 KEGG: bce:BC1906 phage protein; hypothetical protein 3785427 8327438 Amir_3248 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101001.1 3784471 R 446462 CDS YP_003101002.1 256377342 8327439 complement(3785424..3787232) 1 NC_013093.1 KEGG: rsp:RSP_3854 ICE nucleation protein; hypothetical protein 3787232 8327439 Amir_3249 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101002.1 3785424 R 446462 CDS YP_003101003.1 256377343 8327440 complement(3787377..3787706) 1 NC_013093.1 hypothetical protein 3787706 8327440 Amir_3250 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101003.1 3787377 R 446462 CDS YP_003101004.1 256377344 8327441 complement(3787760..3787987) 1 NC_013093.1 hypothetical protein 3787987 8327441 Amir_3251 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101004.1 3787760 R 446462 CDS YP_003101005.1 256377345 8327442 complement(3788053..3788676) 1 NC_013093.1 hypothetical protein 3788676 8327442 Amir_3252 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101005.1 3788053 R 446462 CDS YP_003101006.1 256377346 8327443 complement(3788667..3789116) 1 NC_013093.1 hypothetical protein 3789116 8327443 Amir_3253 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101006.1 3788667 R 446462 CDS YP_003101007.1 256377347 8327444 complement(3789113..3789433) 1 NC_013093.1 hypothetical protein 3789433 8327444 Amir_3254 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101007.1 3789113 R 446462 CDS YP_003101008.1 256377348 8327445 complement(3789438..3789743) 1 NC_013093.1 hypothetical protein 3789743 8327445 Amir_3255 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101008.1 3789438 R 446462 CDS YP_003101009.1 256377349 8327446 complement(3789899..3790264) 1 NC_013093.1 hypothetical protein 3790264 8327446 Amir_3256 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101009.1 3789899 R 446462 CDS YP_003101010.1 256377350 8327447 complement(3790261..3790446) 1 NC_013093.1 hypothetical protein 3790446 8327447 Amir_3257 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101010.1 3790261 R 446462 CDS YP_003101011.1 256377351 8327448 3790603..3790800 1 NC_013093.1 hypothetical protein 3790800 8327448 Amir_3258 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101011.1 3790603 D 446462 CDS YP_003101012.1 256377352 8327449 complement(3790809..3791798) 1 NC_013093.1 KEGG: bbt:BBta_5785 phage major head protein; hypothetical protein 3791798 8327449 Amir_3259 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101012.1 3790809 R 446462 CDS YP_003101013.1 256377353 8327450 complement(3791912..3792271) 1 NC_013093.1 hypothetical protein 3792271 8327450 Amir_3260 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101013.1 3791912 R 446462 CDS YP_003101014.1 256377354 8327451 complement(3792880..3793845) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3793845 8327451 Amir_3261 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101014.1 3792880 R 446462 CDS YP_003101015.1 256377355 8327452 complement(3793851..3795320) 1 NC_013093.1 PFAM: protein of unknown function DUF1483; hypothetical protein 3795320 8327452 Amir_3262 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101015.1 3793851 R 446462 CDS YP_003101016.1 256377356 8327453 3795474..3796301 1 NC_013093.1 hypothetical protein 3796301 8327453 Amir_3263 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101016.1 3795474 D 446462 CDS YP_003101017.1 256377357 8327454 complement(3796303..3797943) 1 NC_013093.1 PFAM: terminase; KEGG: bca:BCE_0397 phage terminase, large subunit; terminase 3797943 8327454 Amir_3264 Actinosynnema mirum DSM 43827 terminase YP_003101017.1 3796303 R 446462 CDS YP_003101018.1 256377358 8327455 complement(3798032..3798493) 1 NC_013093.1 TIGRFAM: phage terminase, small subunit, P27 family; PFAM: terminase small subunit P27; KEGG: rsh:Rsph17029_0646 P27 family phage terminase small subunit; phage terminase, small subunit, P27 family 3798493 8327455 Amir_3265 Actinosynnema mirum DSM 43827 phage terminase, small subunit, P27 family YP_003101018.1 3798032 R 446462 CDS YP_003101019.1 256377359 8327456 complement(3798620..3799033) 1 NC_013093.1 hypothetical protein 3799033 8327456 Amir_3266 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101019.1 3798620 R 446462 CDS YP_003101020.1 256377360 8327457 complement(3799017..3799598) 1 NC_013093.1 hypothetical protein 3799598 8327457 Amir_3267 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101020.1 3799017 R 446462 CDS YP_003101021.1 256377361 8327458 complement(3799790..3800062) 1 NC_013093.1 hypothetical protein 3800062 8327458 Amir_3268 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101021.1 3799790 R 446462 CDS YP_003101022.1 256377362 8327460 complement(3800611..3801681) 1 NC_013093.1 hypothetical protein 3801681 8327460 Amir_3270 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101022.1 3800611 R 446462 CDS YP_003101023.1 256377363 8327461 complement(3801877..3802719) 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 3802719 8327461 Amir_3271 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003101023.1 3801877 R 446462 CDS YP_003101024.1 256377364 8327462 3802797..3803426 1 NC_013093.1 hypothetical protein 3803426 8327462 Amir_3272 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101024.1 3802797 D 446462 CDS YP_003101025.1 256377365 8327463 3803436..3804275 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 3804275 8327463 Amir_3273 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003101025.1 3803436 D 446462 CDS YP_003101026.1 256377366 8327464 complement(3804502..3805287) 1 NC_013093.1 PFAM: methyltransferase type 11; Cyclopropane-fatty- acyl-phospholipid synthase; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: hypothetical protein; type 11 methyltransferase 3805287 8327464 Amir_3274 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003101026.1 3804502 R 446462 CDS YP_003101027.1 256377367 8327465 complement(3805284..3806099) 1 NC_013093.1 PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; Cyclopropane-fatty-acyl-phospholipid synthase; methyltransferase type 12; KEGG: hypothetical protein; type 11 methyltransferase 3806099 8327465 Amir_3275 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003101027.1 3805284 R 446462 CDS YP_003101028.1 256377368 8327466 complement(3806164..3807387) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 3807387 8327466 Amir_3276 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101028.1 3806164 R 446462 CDS YP_003101029.1 256377369 8327467 complement(3807416..3808633) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 3808633 8327467 Amir_3277 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101029.1 3807416 R 446462 CDS YP_003101030.1 256377370 8327468 complement(3808681..3809337) 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: rce:RC1_1081 O-methyltransferase; caffeoyl-CoA O-methyltransferase 3809337 8327468 Amir_3278 Actinosynnema mirum DSM 43827 caffeoyl-CoA O-methyltransferase YP_003101030.1 3808681 R 446462 CDS YP_003101031.1 256377371 8327469 3809590..3810456 1 NC_013093.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: aba:Acid345_4328 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase 3810456 8327469 Amir_3279 Actinosynnema mirum DSM 43827 3-hydroxyacyl-CoA dehydrogenase YP_003101031.1 3809590 D 446462 CDS YP_003101032.1 256377372 8327470 3810453..3810728 1 NC_013093.1 KEGG: gbm:Gbem_0719 hypothetical protein; hypothetical protein 3810728 8327470 Amir_3280 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101032.1 3810453 D 446462 CDS YP_003101033.1 256377373 8327471 3810725..3811912 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: hch:HCH_03452 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 3811912 8327471 Amir_3281 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003101033.1 3810725 D 446462 CDS YP_003101034.1 256377374 8327472 3811909..3813000 1 NC_013093.1 TIGRFAM: FkbH like protein; HAD-superfamily phosphatase, subfamily IIIC; KEGG: nmu:Nmul_A2515 FkbH domain-containing protein; FkbH like protein 3813000 8327472 Amir_3282 Actinosynnema mirum DSM 43827 FkbH like protein YP_003101034.1 3811909 D 446462 CDS YP_003101035.1 256377375 8327473 3813054..3815063 1 NC_013093.1 PFAM: carbamoyltransferase; KEGG: mlo:mlr6171 nodulation protein NolO; carbamoyltransferase 3815063 8327473 Amir_3283 Actinosynnema mirum DSM 43827 carbamoyltransferase YP_003101035.1 3813054 D 446462 CDS YP_003101036.1 256377376 8327474 3815095..3815421 1 NC_013093.1 KEGG: mag:amb2610 O-linked N-acetylglucosamine transferase; O-linked N-acetylglucosamine transferase 3815421 8327474 Amir_3284 Actinosynnema mirum DSM 43827 O-linked N-acetylglucosamine transferase YP_003101036.1 3815095 D 446462 CDS YP_003101037.1 256377377 8327475 3815614..3816543 1 NC_013093.1 PFAM: ROK family protein; KEGG: met:M446_2296 ROK family protein; ROK family protein 3816543 8327475 Amir_3285 Actinosynnema mirum DSM 43827 ROK family protein YP_003101037.1 3815614 D 446462 CDS YP_003101038.1 256377378 8327476 complement(3816501..3816998) 1 NC_013093.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 3816998 8327476 Amir_3286 Actinosynnema mirum DSM 43827 3-dehydroquinate dehydratase YP_003101038.1 3816501 R 446462 CDS YP_003101039.1 256377379 8327477 3817176..3818342 1 NC_013093.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: rpb:RPB_2068 DegT/DnrJ/EryC1/StrS aminotransferase; glutamine--scyllo-inositol transaminase 3818342 8327477 Amir_3287 Actinosynnema mirum DSM 43827 glutamine--scyllo-inositol transaminase YP_003101039.1 3817176 D 446462 CDS YP_003101040.1 256377380 8327478 3818416..3819540 1 NC_013093.1 PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; KEGG: rpb:RPB_2066 oxidoreductase-like; oxidoreductase domain-containing protein 3819540 8327478 Amir_3288 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003101040.1 3818416 D 446462 CDS YP_003101041.1 256377381 8327479 3819540..3820334 1 NC_013093.1 TIGRFAM: AHBA synthesis associated protein; HAD- superfamily hydrolase, subfamily IA, variant 3; HAD- superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpb:RPB_2065 HAD-superfamily hydrolase; AHBA synthesis associated protein 3820334 8327479 Amir_3289 Actinosynnema mirum DSM 43827 AHBA synthesis associated protein YP_003101041.1 3819540 D 446462 CDS YP_003101042.1 256377382 8327480 complement(3820381..3821952) 1 NC_013093.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 3821952 mhpA 8327480 mhpA Actinosynnema mirum DSM 43827 3-(3-hydroxyphenyl)propionate hydroxylase YP_003101042.1 3820381 R 446462 CDS YP_003101043.1 256377383 8327481 complement(3821957..3822733) 1 NC_013093.1 PFAM: N-acetyltransferase; KEGG: si:rp71-1f1.6; N-acetyltransferase 3822733 8327481 Amir_3291 Actinosynnema mirum DSM 43827 N-acetyltransferase YP_003101043.1 3821957 R 446462 CDS YP_003101044.1 256377384 8327482 complement(3822742..3834366) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; beta-ketoacyl synthase; acyl transferase; alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; KEGG: met:M446_0172 beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR 3834366 8327482 Amir_3292 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101044.1 3822742 R 446462 CDS YP_003101045.1 256377385 8327483 complement(3834374..3844600) 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 3844600 8327483 Amir_3293 Actinosynnema mirum DSM 43827 acyl transferase YP_003101045.1 3834374 R 446462 CDS YP_003101046.1 256377386 8327484 complement(3844681..3864987) 1 NC_013093.1 PFAM: acyl transferase; AMP-dependent synthetase and ligase; beta-ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I; acyl transferase 3864987 8327484 Amir_3294 Actinosynnema mirum DSM 43827 acyl transferase YP_003101046.1 3844681 R 446462 CDS YP_003101047.1 256377387 8327485 3865365..3866054 1 NC_013093.1 hypothetical protein 3866054 8327485 Amir_3295 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101047.1 3865365 D 446462 CDS YP_003101048.1 256377388 8327486 3866242..3867291 1 NC_013093.1 PFAM: 3-dehydroquinate synthase; KEGG: gsu:GSU2025 3-dehydroquinate synthase; 3-dehydroquinate synthase 3867291 8327486 Amir_3296 Actinosynnema mirum DSM 43827 3-dehydroquinate synthase YP_003101048.1 3866242 D 446462 CDS YP_003101049.1 256377389 8327487 complement(3867406..3870132) 1 NC_013093.1 PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; KEGG: vei:Veis_2932 regulatory protein, LuxR; LuxR family transcriptional regulator 3870132 8327487 Amir_3297 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101049.1 3867406 R 446462 CDS YP_003101050.1 256377390 8327488 3871496..3871909 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: GNAT family acetyltransferase; GCN5-like N-acetyltransferase 3871909 8327488 Amir_3298 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101050.1 3871496 D 446462 CDS YP_003101051.1 256377391 8327489 complement(3871967..3872809) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 3872809 8327489 Amir_3299 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003101051.1 3871967 R 446462 CDS YP_003101052.1 256377392 8327490 3872966..3873964 1 NC_013093.1 KEGG: aav:Aave_4523 superoxide dismutase; superoxide dismutase 3873964 8327490 Amir_3300 Actinosynnema mirum DSM 43827 superoxide dismutase YP_003101052.1 3872966 D 446462 CDS YP_003101053.1 256377393 8327491 3874243..3875700 1 NC_013093.1 PFAM: glycoside hydrolase family 62; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: glycosyl hydrolase family 62 protein; glycoside hydrolase family protein 3875700 8327491 Amir_3301 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101053.1 3874243 D 446462 CDS YP_003101054.1 256377394 8327492 3875783..3877381 1 NC_013093.1 PFAM: glycoside hydrolase family 43; KEGG: xylosidase/glycosyl hydrolase; glycoside hydrolase family protein 3877381 8327492 Amir_3302 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101054.1 3875783 D 446462 CDS YP_003101055.1 256377395 8327493 3877420..3878730 1 NC_013093.1 PFAM: glycoside hydrolase family 62; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: hypothetical protein; glycoside hydrolase family protein 3878730 8327493 Amir_3303 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101055.1 3877420 D 446462 CDS YP_003101056.1 256377396 8327494 3878775..3879851 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: bur:Bcep18194_B2373 LacI family transcription regulator; LacI family transcriptional regulator 3879851 8327494 Amir_3304 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003101056.1 3878775 D 446462 CDS YP_003101057.1 256377397 8327495 complement(3879900..3881114) 1 NC_013093.1 KEGG: mxa:MXAN_1686 acetyltransferase, GNAT family; hypothetical protein 3881114 8327495 Amir_3305 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101057.1 3879900 R 446462 CDS YP_003101058.1 256377398 8327496 3881218..3881787 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bcy:Bcer98_3256 TetR family transcriptional regulator; TetR family transcriptional regulator 3881787 8327496 Amir_3306 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101058.1 3881218 D 446462 CDS YP_003101059.1 256377399 8327497 3881859..3882383 1 NC_013093.1 PFAM: isochorismatase hydrolase; KEGG: bxe:Bxe_C0259 isochorismatase hydrolase family protein; isochorismatase hydrolase 3882383 8327497 Amir_3307 Actinosynnema mirum DSM 43827 isochorismatase hydrolase YP_003101059.1 3881859 D 446462 CDS YP_003101060.1 256377400 8327498 complement(3882421..3885438) 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: scl:sce5225 protein kinase; transcriptional regulator, winged helix family 3885438 8327498 Amir_3308 Actinosynnema mirum DSM 43827 transcriptional regulator, winged helix family YP_003101060.1 3882421 R 446462 CDS YP_003101061.1 256377401 8327499 3885560..3886279 1 NC_013093.1 KEGG: scl:sce8587 hypothetical protein; hypothetical protein 3886279 8327499 Amir_3309 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101061.1 3885560 D 446462 CDS YP_003101062.1 256377402 8327500 complement(3886345..3887115) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bid:Bind_1892 TetR family transcriptional regulator; TetR family transcriptional regulator 3887115 8327500 Amir_3310 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101062.1 3886345 R 446462 CDS YP_003101063.1 256377403 8327501 3887208..3888134 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: short-chain oxidoreductase protein; short-chain dehydrogenase/reductase SDR 3888134 8327501 Amir_3311 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101063.1 3887208 D 446462 CDS YP_003101064.1 256377404 8327502 3888175..3888381 1 NC_013093.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: bcm:Bcenmc03_4438 4-oxalocrotonate tautomerase; 4-oxalocrotonate tautomerase 3888381 8327502 Amir_3312 Actinosynnema mirum DSM 43827 4-oxalocrotonate tautomerase YP_003101064.1 3888175 D 446462 CDS YP_003101065.1 256377405 8327503 complement(3888426..3888971) 1 NC_013093.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: mes:Meso_4307 bifunctional deaminase- reductase-like; bifunctional deaminase-reductase domain-containing protein 3888971 8327503 Amir_3313 Actinosynnema mirum DSM 43827 bifunctional deaminase-reductase domain-containing protein YP_003101065.1 3888426 R 446462 CDS YP_003101066.1 256377406 8327504 complement(3889055..3889723) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 3889723 8327504 Amir_3314 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101066.1 3889055 R 446462 CDS YP_003101067.1 256377407 8327505 complement(3889724..3890905) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3890905 8327505 Amir_3315 Actinosynnema mirum DSM 43827 histidine kinase YP_003101067.1 3889724 R 446462 CDS YP_003101068.1 256377408 8327506 3891062..3892516 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: atu:Atu2171 hydrolase; TAP domain-containing protein 3892516 8327506 Amir_3316 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003101068.1 3891062 D 446462 CDS YP_003101069.1 256377409 8327507 complement(3892588..3893877) 1 NC_013093.1 KEGG: eli:ELI_05955 beta-lactamase; beta-lactamase class A-like protein 3893877 8327507 Amir_3317 Actinosynnema mirum DSM 43827 beta-lactamase class A-like protein YP_003101069.1 3892588 R 446462 CDS YP_003101070.1 256377410 8327508 complement(3893896..3894546) 1 NC_013093.1 hypothetical protein 3894546 8327508 Amir_3318 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101070.1 3893896 R 446462 CDS YP_003101071.1 256377411 8327510 complement(3895604..3896818) 1 NC_013093.1 KEGG: dvm:DvMF_2570 hypothetical protein; hypothetical protein 3896818 8327510 Amir_3320 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101071.1 3895604 R 446462 CDS YP_003101072.1 256377412 8327511 complement(3896815..3898071) 1 NC_013093.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: dde:Dde_0483 ATPase; ATPase 3898071 8327511 Amir_3321 Actinosynnema mirum DSM 43827 ATPase YP_003101072.1 3896815 R 446462 CDS YP_003101073.1 256377413 8327512 complement(3898155..3899558) 1 NC_013093.1 KEGG: rsq:Rsph17025_0280 sporulation domain- containing protein; hypothetical protein 3899558 8327512 Amir_3322 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101073.1 3898155 R 446462 CDS YP_003101074.1 256377414 8327513 complement(3899723..3900349) 1 NC_013093.1 hypothetical protein 3900349 8327513 Amir_3323 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101074.1 3899723 R 446462 CDS YP_003101075.1 256377415 8327514 complement(3900346..3901152) 1 NC_013093.1 PFAM: regulatory protein MarR; KEGG: scl:sce6114 hypothetical protein; MarR family transcriptional regulator 3901152 8327514 Amir_3324 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003101075.1 3900346 R 446462 CDS YP_003101076.1 256377416 8327515 3901214..3903346 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: sus:Acid_0469 peptidase S9B dipeptidylpeptidase IV subunit; Dipeptidyl-peptidase IV 3903346 8327515 Amir_3325 Actinosynnema mirum DSM 43827 Dipeptidyl-peptidase IV YP_003101076.1 3901214 D 446462 CDS YP_003101077.1 256377417 8327516 3903655..3904578 1 NC_013093.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: aeh:Mlg_1632 AraC family transcriptional regulator; AraC family transcriptional regulator 3904578 8327516 Amir_3326 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101077.1 3903655 D 446462 CDS YP_003101078.1 256377418 8327517 3904689..3906488 1 NC_013093.1 PFAM: asparagine synthase; KEGG: swi:Swit_4548 asparagine synthase; asparagine synthase 3906488 8327517 Amir_3327 Actinosynnema mirum DSM 43827 asparagine synthase YP_003101078.1 3904689 D 446462 CDS YP_003101079.1 256377419 8327518 3906485..3906742 1 NC_013093.1 hypothetical protein 3906742 8327518 Amir_3328 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101079.1 3906485 D 446462 CDS YP_003101080.1 256377420 8327519 3906754..3907152 1 NC_013093.1 KEGG: cak:Caul_5192 hypothetical protein; hypothetical protein 3907152 8327519 Amir_3329 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101080.1 3906754 D 446462 CDS YP_003101081.1 256377421 8327520 complement(3907424..3907735) 1 NC_013093.1 hypothetical protein 3907735 8327520 Amir_3330 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101081.1 3907424 R 446462 CDS YP_003101082.1 256377422 8327521 complement(3907835..3908881) 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pfl:PFL_2250 transcriptional activator FtrA; AraC family transcriptional regulator 3908881 8327521 Amir_3331 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101082.1 3907835 R 446462 CDS YP_003101083.1 256377423 8327522 3908959..3909351 1 NC_013093.1 PFAM: cupin; KEGG: bja:blr5564 hypothetical protein; cyclic nucleotide-binding protein 3909351 8327522 Amir_3332 Actinosynnema mirum DSM 43827 cyclic nucleotide-binding protein YP_003101083.1 3908959 D 446462 CDS YP_003101084.1 256377424 8327523 complement(3909355..3910038) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bid:Bind_0033 TetR family transcriptional regulator; TetR family transcriptional regulator 3910038 8327523 Amir_3333 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101084.1 3909355 R 446462 CDS YP_003101085.1 256377425 8327524 3910141..3911040 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bid:Bind_0032 short-chain dehydrogenase/reductase SDR; short chain dehydrogenase 3911040 8327524 Amir_3334 Actinosynnema mirum DSM 43827 short chain dehydrogenase YP_003101085.1 3910141 D 446462 CDS YP_003101086.1 256377426 8327525 complement(3911164..3912900) 1 NC_013093.1 PFAM: glycoside hydrolase family 5; protein of unknown function DUF291; KEGG: bha:BH0603 endo-beta-1,4-glucanase (celulase B); Cellulase 3912900 8327525 Amir_3335 Actinosynnema mirum DSM 43827 Cellulase YP_003101086.1 3911164 R 446462 CDS YP_003101087.1 256377427 8327526 3913209..3914822 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH0482 lipoprotein; family 1 extracellular solute-binding protein 3914822 8327526 Amir_3336 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003101087.1 3913209 D 446462 CDS YP_003101088.1 256377428 8327528 complement(3915744..3916769) 1 NC_013093.1 KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 3916769 8327528 Amir_3338 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003101088.1 3915744 R 446462 CDS YP_003101089.1 256377429 8327529 complement(3916885..3917724) 1 NC_013093.1 PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: scl:sce8968 nucleotide-diphosphate-sugar epimerase; NmrA family protein 3917724 8327529 Amir_3339 Actinosynnema mirum DSM 43827 NmrA family protein YP_003101089.1 3916885 R 446462 CDS YP_003101090.1 256377430 8327530 3917823..3918200 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: aav:Aave_1296 transcriptional regulator, HxlR family; HxlR family transcriptional regulator 3918200 8327530 Amir_3340 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003101090.1 3917823 D 446462 CDS YP_003101091.1 256377431 8327532 3919105..3919569 1 NC_013093.1 hypothetical protein 3919569 8327532 Amir_3342 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101091.1 3919105 D 446462 CDS YP_003101092.1 256377432 8327534 complement(3920479..3921129) 1 NC_013093.1 hypothetical protein 3921129 8327534 Amir_3344 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101092.1 3920479 R 446462 CDS YP_003101093.1 256377433 8327535 3921150..3921938 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: pzu:PHZ_c1878 hypothetical protein; alpha/beta hydrolase fold protein 3921938 8327535 Amir_3345 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101093.1 3921150 D 446462 CDS YP_003101094.1 256377434 8327536 3922119..3922382 1 NC_013093.1 hypothetical protein 3922382 8327536 Amir_3346 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101094.1 3922119 D 446462 CDS YP_003101095.1 256377435 8327537 complement(3922438..3922704) 1 NC_013093.1 hypothetical protein 3922704 8327537 Amir_3347 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101095.1 3922438 R 446462 CDS YP_003101096.1 256377436 8327538 complement(3922879..3923676) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: bat:BAS3592 alpha/beta fold family hydrolase; alpha/beta hydrolase fold protein 3923676 8327538 Amir_3348 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101096.1 3922879 R 446462 CDS YP_003101097.1 256377437 8327539 3923830..3924831 1 NC_013093.1 KEGG: sus:Acid_6922 natural resistance-associated macrophage protein; hypothetical protein 3924831 8327539 Amir_3349 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101097.1 3923830 D 446462 CDS YP_003101098.1 256377438 8327540 3925037..3925981 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: rso:RS05496 oxidoreductase protein; short-chain dehydrogenase/reductase SDR 3925981 8327540 Amir_3350 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101098.1 3925037 D 446462 CDS YP_003101099.1 256377439 8327541 complement(3926044..3926307) 1 NC_013093.1 KEGG: afw:Anae109_3772 hypothetical protein; hypothetical protein 3926307 8327541 Amir_3351 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101099.1 3926044 R 446462 CDS YP_003101100.1 256377440 8327542 complement(3926429..3927757) 1 NC_013093.1 PFAM: carboxylesterase type B; KEGG: swi:Swit_1148 carboxylesterase, type B; carboxylesterase type B 3927757 8327542 Amir_3352 Actinosynnema mirum DSM 43827 carboxylesterase type B YP_003101100.1 3926429 R 446462 CDS YP_003101101.1 256377441 8327543 complement(3927789..3928787) 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: nar:Saro_2457 beta-lactamase-like; beta-lactamase domain-containing protein 3928787 8327543 Amir_3353 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003101101.1 3927789 R 446462 CDS YP_003101102.1 256377442 8327544 complement(3928866..3929546) 1 NC_013093.1 hypothetical protein 3929546 8327544 Amir_3354 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101102.1 3928866 R 446462 CDS YP_003101103.1 256377443 8327545 complement(3929878..3930843) 1 NC_013093.1 PFAM: TAP domain protein; KEGG: NACA, TEBP; nascent polypeptide-associated complex alpha subunit; TAP domain-containing protein 3930843 8327545 Amir_3355 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003101103.1 3929878 R 446462 CDS YP_003101104.1 256377444 8327546 3930994..3932274 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3932274 8327546 Amir_3356 Actinosynnema mirum DSM 43827 histidine kinase YP_003101104.1 3930994 D 446462 CDS YP_003101105.1 256377445 8327547 3932285..3932944 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: swi:Swit_3205 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 3932944 8327547 Amir_3357 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101105.1 3932285 D 446462 CDS YP_003101106.1 256377446 8327548 complement(3932954..3934537) 1 NC_013093.1 hypothetical protein 3934537 8327548 Amir_3358 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101106.1 3932954 R 446462 CDS YP_003101107.1 256377447 8327549 complement(3934640..3935632) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: bid:Bind_1144 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 3935632 8327549 Amir_3359 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003101107.1 3934640 R 446462 CDS YP_003101108.1 256377448 8327550 complement(3935634..3936218) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce7471 TetR family transcriptional regulator; TetR family transcriptional regulator 3936218 8327550 Amir_3360 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101108.1 3935634 R 446462 CDS YP_003101109.1 256377449 8327551 complement(3936259..3936765) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bac:BamMC406_4517 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 3936765 8327551 Amir_3361 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101109.1 3936259 R 446462 CDS YP_003101110.1 256377450 8327552 3937213..3937773 1 NC_013093.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein; bifunctional deaminase-reductase domain-containing protein 3937773 8327552 Amir_3362 Actinosynnema mirum DSM 43827 bifunctional deaminase-reductase domain-containing protein YP_003101110.1 3937213 D 446462 CDS YP_003101111.1 256377451 8327555 complement(3938634..3939644) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: bxe:Bxe_B0085 norsolorinic acid reductase; aldo/keto reductase 3939644 8327555 Amir_3365 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101111.1 3938634 R 446462 CDS YP_003101112.1 256377452 8327556 3939750..3940679 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bur:Bcep18194_C7080 AraC family transcriptional regulator; AraC family transcriptional regulator 3940679 8327556 Amir_3366 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101112.1 3939750 D 446462 CDS YP_003101113.1 256377453 8327557 complement(3940659..3941189) 1 NC_013093.1 hypothetical protein 3941189 8327557 Amir_3367 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101113.1 3940659 R 446462 CDS YP_003101114.1 256377454 8327558 3941285..3943633 1 NC_013093.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: mno:Mnod_8717 D-xylulose 5-phosphate/D- fructose 6-phosphate phosphoketolase; phosphoketolase 3943633 8327558 Amir_3368 Actinosynnema mirum DSM 43827 phosphoketolase YP_003101114.1 3941285 D 446462 CDS YP_003101115.1 256377455 8327559 3943630..3944721 1 NC_013093.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: bsu:BSU29470 acetate kinase; acetate kinase 3944721 8327559 Amir_3369 Actinosynnema mirum DSM 43827 acetate kinase YP_003101115.1 3943630 D 446462 CDS YP_003101116.1 256377456 8327560 complement(3944728..3945393) 1 NC_013093.1 hypothetical protein 3945393 8327560 Amir_3370 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101116.1 3944728 R 446462 CDS YP_003101117.1 256377457 8327561 3945485..3945910 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: oan:Oant_1677 NUDIX hydrolase; NUDIX hydrolase 3945910 8327561 Amir_3371 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003101117.1 3945485 D 446462 CDS YP_003101118.1 256377458 8327562 3946003..3946254 1 NC_013093.1 hypothetical protein 3946254 8327562 Amir_3372 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101118.1 3946003 D 446462 CDS YP_003101119.1 256377459 8327563 3946558..3947166 1 NC_013093.1 hypothetical protein 3947166 8327563 Amir_3373 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101119.1 3946558 D 446462 CDS YP_003101120.1 256377460 8327564 3947232..3947450 1 NC_013093.1 KEGG: ccv:CCV52592_2062 hypothetical protein; hypothetical protein 3947450 8327564 Amir_3374 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101120.1 3947232 D 446462 CDS YP_003101121.1 256377461 8327565 3947477..3947797 1 NC_013093.1 hypothetical protein 3947797 8327565 Amir_3375 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101121.1 3947477 D 446462 CDS YP_003101122.1 256377462 8327566 complement(3947820..3949580) 1 NC_013093.1 PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: scl:sce2120 pyruvate decarboxylase; thiamine pyrophosphate TPP-binding domain-containing protein 3949580 8327566 Amir_3376 Actinosynnema mirum DSM 43827 thiamine pyrophosphate TPP-binding domain-containing protein YP_003101122.1 3947820 R 446462 CDS YP_003101123.1 256377463 8327567 complement(3949577..3950224) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; KEGG: noc:Noc_0592 zinc-containing alcohol dehydrogenase superfamily protein; alcohol dehydrogenase GroES domain-containing protein 3950224 8327567 Amir_3377 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003101123.1 3949577 R 446462 CDS YP_003101124.1 256377464 8327568 complement(3950401..3951231) 1 NC_013093.1 PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: spe:Spro_1223 glycoside hydrolase family protein; Fibronectin type III domain-containing protein 3951231 8327568 Amir_3378 Actinosynnema mirum DSM 43827 Fibronectin type III domain-containing protein YP_003101124.1 3950401 R 446462 CDS YP_003101125.1 256377465 8327569 complement(3951338..3952585) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: csa:Csal_3232 major facilitator superfamily MFS_1; major facilitator superfamily protein 3952585 8327569 Amir_3379 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101125.1 3951338 R 446462 CDS YP_003101126.1 256377466 8327570 3952653..3953552 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: smt:Smal_0276 transcriptional regulator, LysR family; LysR family transcriptional regulator 3953552 8327570 Amir_3380 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003101126.1 3952653 D 446462 CDS YP_003101127.1 256377467 8327571 complement(3953563..3954576) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 3954576 8327571 Amir_3381 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101127.1 3953563 R 446462 CDS YP_003101128.1 256377468 8327572 3954765..3955766 1 NC_013093.1 PFAM: regulatory protein LacI; SMART: regulatory protein LacI; KEGG: atc:AGR_L_1215 hypothetical protein; LacI family transcriptional regulator 3955766 8327572 Amir_3382 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003101128.1 3954765 D 446462 CDS YP_003101129.1 256377469 8327573 3955763..3957355 1 NC_013093.1 KEGG: atu:Atu4253 hypothetical protein; hypothetical protein 3957355 8327573 Amir_3383 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101129.1 3955763 D 446462 CDS YP_003101130.1 256377470 8327574 3957355..3959562 1 NC_013093.1 PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; KEGG: scl:sce2622 N-methylhydantoinase A, beta subunit; hydantoinase/oxoprolinase 3959562 8327574 Amir_3384 Actinosynnema mirum DSM 43827 hydantoinase/oxoprolinase YP_003101130.1 3957355 D 446462 CDS YP_003101131.1 256377471 8327575 3959559..3960107 1 NC_013093.1 hypothetical protein 3960107 8327575 Amir_3385 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101131.1 3959559 D 446462 CDS YP_003101132.1 256377472 8327576 3960111..3961382 1 NC_013093.1 PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; Citrate transporter; KEGG: azc:AZC_1182 H+/citrate symporter; TRAP dicarboxylate transporter subunit DctM 3961382 8327576 Amir_3386 Actinosynnema mirum DSM 43827 TRAP dicarboxylate transporter subunit DctM YP_003101132.1 3960111 D 446462 CDS YP_003101133.1 256377473 8327577 complement(3961438..3962070) 1 NC_013093.1 KEGG: Muc19; mucin 19; hypothetical protein 3962070 8327577 Amir_3387 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101133.1 3961438 R 446462 CDS YP_003101134.1 256377474 8327578 complement(3962558..3963139) 1 NC_013093.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH- dependent FMN reductase; KEGG: aav:Aave_3540 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 3963139 8327578 Amir_3388 Actinosynnema mirum DSM 43827 NAD(P)H dehydrogenase (quinone) YP_003101134.1 3962558 R 446462 CDS YP_003101135.1 256377475 8327579 3963237..3963800 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bpt:Bpet2251 TetR family transcriptional regulator; TetR family transcriptional regulator 3963800 8327579 Amir_3389 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101135.1 3963237 D 446462 CDS YP_003101136.1 256377476 8327581 complement(3964177..3964728) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce1138 acetyltransferase; GCN5-like N-acetyltransferase 3964728 8327581 Amir_3391 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101136.1 3964177 R 446462 CDS YP_003101137.1 256377477 8327582 complement(3964803..3965003) 1 NC_013093.1 hypothetical protein 3965003 8327582 Amir_3392 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101137.1 3964803 R 446462 CDS YP_003101138.1 256377478 8327584 3965998..3968550 1 NC_013093.1 PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; KEGG: acp:A2cp1_1693 protein of unknown function DUF470; hypothetical protein 3968550 8327584 Amir_3394 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101138.1 3965998 D 446462 CDS YP_003101139.1 256377479 8327585 3968568..3969872 1 NC_013093.1 PFAM: esterase; KEGG: bcm:Bcenmc03_5695 esterase; esterase 3969872 8327585 Amir_3395 Actinosynnema mirum DSM 43827 esterase YP_003101139.1 3968568 D 446462 CDS YP_003101140.1 256377480 8327586 complement(3969917..3970417) 1 NC_013093.1 hypothetical protein 3970417 8327586 Amir_3396 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101140.1 3969917 R 446462 CDS YP_003101141.1 256377481 8327587 3970759..3972315 1 NC_013093.1 PFAM: Amidohydrolase 3; KEGG: rce:RC1_3136 amidohydrolase family protein; Amidohydrolase 3 3972315 8327587 Amir_3397 Actinosynnema mirum DSM 43827 Amidohydrolase 3 YP_003101141.1 3970759 D 446462 CDS YP_003101142.1 256377482 8327588 complement(3972425..3972817) 1 NC_013093.1 KEGG: mxa:MXAN_4385 beta-alanyl-CoA:ammonia lyase; beta-alanyl-CoA:ammonia lyase 3972817 8327588 Amir_3398 Actinosynnema mirum DSM 43827 beta-alanyl-CoA:ammonia lyase YP_003101142.1 3972425 R 446462 CDS YP_003101143.1 256377483 8327589 3973078..3973431 1 NC_013093.1 PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bcy:Bcer98_1077 regulatory protein GntR HTH; GntR family transcriptional regulator 3973431 8327589 Amir_3399 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003101143.1 3973078 D 446462 CDS YP_003101144.1 256377484 8327590 3973462..3974208 1 NC_013093.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: mxa:MXAN_2794 transcriptional regulator, TetR family; TetR family transcriptional regulator 3974208 8327590 Amir_3400 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101144.1 3973462 D 446462 CDS YP_003101145.1 256377485 8327591 complement(3974186..3974374) 1 NC_013093.1 PFAM: PspC domain protein; KEGG: xom:XOO_2087 hypothetical protein; phage shock protein PspC 3974374 8327591 Amir_3401 Actinosynnema mirum DSM 43827 phage shock protein PspC YP_003101145.1 3974186 R 446462 CDS YP_003101146.1 256377486 8327592 3974730..3975521 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: ank:AnaeK_2710 glycosyl transferase family 2; family 2 glycosyl transferase 3975521 8327592 Amir_3402 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003101146.1 3974730 D 446462 CDS YP_003101147.1 256377487 8327593 complement(3975729..3976073) 1 NC_013093.1 hypothetical protein 3976073 8327593 Amir_3403 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101147.1 3975729 R 446462 CDS YP_003101148.1 256377488 8327594 complement(3976561..3977085) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: nha:Nham_1987 NUDIX hydrolase; NUDIX hydrolase 3977085 8327594 Amir_3404 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003101148.1 3976561 R 446462 CDS YP_003101149.1 256377489 8327595 complement(3977280..3977507) 1 NC_013093.1 hypothetical protein 3977507 8327595 Amir_3405 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101149.1 3977280 R 446462 CDS YP_003101150.1 256377490 8327596 complement(3977708..3978679) 1 NC_013093.1 KEGG: hypothetical protein; PucR family transcriptional regulator 3978679 8327596 Amir_3406 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003101150.1 3977708 R 446462 CDS YP_003101151.1 256377491 8327597 complement(3978995..3979573) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; cupin; SMART: helix-turn-helix domain protein; KEGG: scl:sce6511 transcriptional regulator; XRE family transcriptional regulator 3979573 8327597 Amir_3407 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101151.1 3978995 R 446462 CDS YP_003101152.1 256377492 8327598 complement(3979646..3980365) 1 NC_013093.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 3980365 8327598 Amir_3408 Actinosynnema mirum DSM 43827 thymidine kinase YP_003101152.1 3979646 R 446462 CDS YP_003101153.1 256377493 8327599 3980471..3980785 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: sus:Acid_0652 PadR family transcriptional regulator; PadR family transcriptional regulator 3980785 8327599 Amir_3409 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003101153.1 3980471 D 446462 CDS YP_003101154.1 256377494 8327600 3980782..3981567 1 NC_013093.1 KEGG: ret:RHE_CH02708 hypothetical protein; hypothetical protein 3981567 8327600 Amir_3410 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101154.1 3980782 D 446462 CDS YP_003101155.1 256377495 8327601 complement(3981574..3982983) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: pca:Pcar_1854 major facilitator superfamily permease/BtlA-like; major facilitator superfamily protein 3982983 8327601 Amir_3411 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101155.1 3981574 R 446462 CDS YP_003101156.1 256377496 8327602 complement(3983048..3983824) 1 NC_013093.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: rce:RC1_2887 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 3983824 8327602 Amir_3412 Actinosynnema mirum DSM 43827 glycerophosphoryl diester phosphodiesterase YP_003101156.1 3983048 R 446462 CDS YP_003101157.1 256377497 8327603 3983892..3984353 1 NC_013093.1 KEGG: scl:sce6697 transcriptional regulator; hypothetical protein 3984353 8327603 Amir_3413 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101157.1 3983892 D 446462 CDS YP_003101158.1 256377498 8327604 3984443..3986464 1 NC_013093.1 KEGG: tbd:Tbd_2428 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 3986464 8327604 Amir_3414 Actinosynnema mirum DSM 43827 PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase YP_003101158.1 3984443 D 446462 CDS YP_003101159.1 256377499 8327605 3986488..3987147 1 NC_013093.1 KEGG: she:Shewmr4_3786 glyoxalase/bleomycin resistance protein/dioxygenase; hypothetical protein 3987147 8327605 Amir_3415 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101159.1 3986488 D 446462 CDS YP_003101160.1 256377500 8327606 complement(3987208..3987663) 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 3987663 8327606 Amir_3416 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003101160.1 3987208 R 446462 CDS YP_003101161.1 256377501 8327607 complement(3987700..3988560) 1 NC_013093.1 KEGG: afw:Anae109_1008 Ku family containing protein; TIGRFAM: Ku protein; PFAM: Ku domain protein; SMART: Ku domain protein; Ku domain containing protein 3988560 8327607 Amir_3417 Actinosynnema mirum DSM 43827 Ku domain containing protein YP_003101161.1 3987700 R 446462 CDS YP_003101162.1 256377502 8327608 complement(3988699..3989256) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hne:HNE_3215 acetyltransferase; GCN5-like N-acetyltransferase 3989256 8327608 Amir_3418 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101162.1 3988699 R 446462 CDS YP_003101163.1 256377503 8327609 3989388..3990209 1 NC_013093.1 hypothetical protein 3990209 8327609 Amir_3419 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101163.1 3989388 D 446462 CDS YP_003101164.1 256377504 8327610 3990255..3990686 1 NC_013093.1 PFAM: protein of unknown function DUF107; KEGG: sfu:Sfum_2309 protein of unknown function DUF107; hypothetical protein 3990686 8327610 Amir_3420 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101164.1 3990255 D 446462 CDS YP_003101165.1 256377505 8327611 3990698..3991906 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: bcy:Bcer98_1560 hypothetical protein; hypothetical protein 3991906 8327611 Amir_3421 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101165.1 3990698 D 446462 CDS YP_003101166.1 256377506 8327612 complement(3991957..3992145) 1 NC_013093.1 hypothetical protein 3992145 8327612 Amir_3422 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101166.1 3991957 R 446462 CDS YP_003101167.1 256377507 8327613 3992168..3992527 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: hha:Hhal_1112 regulatory protein, ArsR; ArsR family transcriptional regulator 3992527 8327613 Amir_3423 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003101167.1 3992168 D 446462 CDS YP_003101168.1 256377508 8327614 3992524..3993570 1 NC_013093.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: arsenical-resistance protein precursor; K03325 arsenite transporter, ACR3 family; arsenical-resistance protein 3993570 8327614 Amir_3424 Actinosynnema mirum DSM 43827 arsenical-resistance protein YP_003101168.1 3992524 D 446462 CDS YP_003101169.1 256377509 8327615 3993621..3994031 1 NC_013093.1 PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; KEGG: arsenate reductase ArsC; K03741 arsenate reductase; Protein-tyrosine phosphatase, low molecular weight 3994031 8327615 Amir_3425 Actinosynnema mirum DSM 43827 Protein-tyrosine phosphatase, low molecular weight YP_003101169.1 3993621 D 446462 CDS YP_003101170.1 256377510 8327616 3994103..3995170 1 NC_013093.1 KEGG: bph:Bphy_3936 zinc finger SWIM domain- containing protein; hypothetical protein 3995170 8327616 Amir_3426 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101170.1 3994103 D 446462 CDS YP_003101171.1 256377511 8327618 3995887..3996168 1 NC_013093.1 PFAM: ANTAR domain protein; ANTAR domain-containing protein 3996168 8327618 Amir_3428 Actinosynnema mirum DSM 43827 ANTAR domain-containing protein YP_003101171.1 3995887 D 446462 CDS YP_003101172.1 256377512 8327619 complement(3996197..3997570) 1 NC_013093.1 PFAM: amidase; KEGG: met:M446_0555 amidase; amidase 3997570 8327619 Amir_3429 Actinosynnema mirum DSM 43827 amidase YP_003101172.1 3996197 R 446462 CDS YP_003101173.1 256377513 8327620 3997770..3998660 1 NC_013093.1 KEGG: mag:amb0998 hypothetical protein; hypothetical protein 3998660 8327620 Amir_3430 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101173.1 3997770 D 446462 CDS YP_003101174.1 256377514 8327621 3998861..3999451 1 NC_013093.1 KEGG: ppg:PputGB1_1457 hypothetical protein; hypothetical protein 3999451 8327621 Amir_3431 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101174.1 3998861 D 446462 CDS YP_003101175.1 256377515 8327622 complement(3999559..4000083) 1 NC_013093.1 PFAM: protein of unknown function DUF1470; KEGG: jan:Jann_2411 hypothetical protein; hypothetical protein 4000083 8327622 Amir_3432 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101175.1 3999559 R 446462 CDS YP_003101176.1 256377516 8327623 4000098..4000286 1 NC_013093.1 hypothetical protein 4000286 8327623 Amir_3433 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101176.1 4000098 D 446462 CDS YP_003101177.1 256377517 8327624 4000299..4000964 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: ade:Adeh_2880 TetR family transcriptional regulator; TetR family transcriptional regulator 4000964 8327624 Amir_3434 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101177.1 4000299 D 446462 CDS YP_003101178.1 256377518 8327625 complement(4001187..4001552) 1 NC_013093.1 hypothetical protein 4001552 8327625 Amir_3435 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101178.1 4001187 R 446462 CDS YP_003101179.1 256377519 8327626 4001870..4002547 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4002547 8327626 Amir_3436 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101179.1 4001870 D 446462 CDS YP_003101180.1 256377520 8327627 4002535..4003248 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: azc:AZC_4194 dehydrogenases; short-chain dehydrogenase/reductase SDR 4003248 8327627 Amir_3437 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101180.1 4002535 D 446462 CDS YP_003101181.1 256377521 8327628 complement(4003208..4004002) 1 NC_013093.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: ank:AnaeK_1955 methionine aminopeptidase, type I; methionine aminopeptidase, type I 4004002 8327628 Amir_3438 Actinosynnema mirum DSM 43827 methionine aminopeptidase, type I YP_003101181.1 4003208 R 446462 CDS YP_003101182.1 256377522 8327629 4004049..4004309 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: mxa:MXAN_2709 transcriptional regulator; XRE family transcriptional regulator 4004309 8327629 Amir_3439 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101182.1 4004049 D 446462 CDS YP_003101183.1 256377523 8327630 complement(4004327..4005337) 1 NC_013093.1 PFAM: Helix-turn-helix type 11 domain protein; regulatory protein DeoR; protein of unknown function UPF0074; SMART: regulatory protein DeoR; KEGG: scl:sce5223 DeoR family transcriptional regulator; Helix-turn-helix type 11 domain-containing protein 4005337 8327630 Amir_3440 Actinosynnema mirum DSM 43827 Helix-turn-helix type 11 domain-containing protein YP_003101183.1 4004327 R 446462 CDS YP_003101184.1 256377524 8327631 4005370..4006656 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: bbt:BBta_2587 monoxygenase; FAD-binding monooxygenase 4006656 8327631 Amir_3441 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101184.1 4005370 D 446462 CDS YP_003101185.1 256377525 8327632 complement(4006769..4007518) 1 NC_013093.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: kpe:KPK_3034 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 4007518 8327632 Amir_3442 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003101185.1 4006769 R 446462 CDS YP_003101186.1 256377526 8327633 4007579..4009156 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: hypothetical protein LOC100149318; NUDIX hydrolase 4009156 8327633 Amir_3443 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003101186.1 4007579 D 446462 CDS YP_003101187.1 256377527 8327634 complement(4009128..4009751) 1 NC_013093.1 hypothetical protein 4009751 8327634 Amir_3444 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101187.1 4009128 R 446462 CDS YP_003101188.1 256377528 8327635 complement(4009778..4010566) 1 NC_013093.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: scl:sce7572 DNA polymerase III, epsilon subunit; exonuclease RNase T and DNA polymerase III 4010566 8327635 Amir_3445 Actinosynnema mirum DSM 43827 exonuclease RNase T and DNA polymerase III YP_003101188.1 4009778 R 446462 CDS YP_003101189.1 256377529 8327636 complement(4010670..4010912) 1 NC_013093.1 hypothetical protein 4010912 8327636 Amir_3446 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101189.1 4010670 R 446462 CDS YP_003101190.1 256377530 8327637 4011959..4012933 1 NC_013093.1 PFAM: integrase family protein; KEGG: mag:amb4250 site-specific tyrosine recombinase XerC; integrase family protein 4012933 8327637 Amir_3447 Actinosynnema mirum DSM 43827 integrase family protein YP_003101190.1 4011959 D 446462 CDS YP_003101191.1 256377531 8327638 4013029..4013874 1 NC_013093.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce1871 AraC family transcriptional regulator; AraC family transcriptional regulator 4013874 8327638 Amir_3448 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101191.1 4013029 D 446462 CDS YP_003101192.1 256377532 8327639 4013941..4014522 1 NC_013093.1 KEGG: cvi:CV_3295 hypothetical protein; hypothetical protein 4014522 8327639 Amir_3449 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101192.1 4013941 D 446462 CDS YP_003101193.1 256377533 8327640 complement(4014596..4015054) 1 NC_013093.1 hypothetical protein 4015054 8327640 Amir_3450 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101193.1 4014596 R 446462 CDS YP_003101194.1 256377534 8327641 complement(4015301..4016104) 1 NC_013093.1 hypothetical protein 4016104 8327641 Amir_3451 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101194.1 4015301 R 446462 CDS YP_003101195.1 256377535 8327642 complement(4016110..4016676) 1 NC_013093.1 hypothetical protein 4016676 8327642 Amir_3452 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101195.1 4016110 R 446462 CDS YP_003101196.1 256377536 8327643 4016788..4018710 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: msl:Msil_1579 peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9 prolyl oligopeptidase active site domain-containing protein 4018710 8327643 Amir_3453 Actinosynnema mirum DSM 43827 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_003101196.1 4016788 D 446462 CDS YP_003101197.1 256377537 8327644 4018707..4019609 1 NC_013093.1 PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: dal:Dalk_3806 peptidase U61 LD- carboxypeptidase A; peptidase U61 LD-carboxypeptidase A 4019609 8327644 Amir_3454 Actinosynnema mirum DSM 43827 peptidase U61 LD-carboxypeptidase A YP_003101197.1 4018707 D 446462 CDS YP_003101198.1 256377538 8327645 4019625..4019768 1 NC_013093.1 hypothetical protein 4019768 8327645 Amir_3455 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101198.1 4019625 D 446462 CDS YP_003101199.1 256377539 8327646 complement(4019738..4020271) 1 NC_013093.1 hypothetical protein 4020271 8327646 Amir_3456 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101199.1 4019738 R 446462 CDS YP_003101200.1 256377540 8327649 4022261..4022911 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hypothetical protein; HAD superfamily hydrolase 4022911 8327649 Amir_3459 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003101200.1 4022261 D 446462 CDS YP_003101201.1 256377541 8327650 4022908..4023942 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: mrd:Mrad2831_1820 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 4023942 8327650 Amir_3460 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003101201.1 4022908 D 446462 CDS YP_003101202.1 256377542 8327651 4023942..4025150 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: pen:PSEEN3343 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 4025150 8327651 Amir_3461 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003101202.1 4023942 D 446462 CDS YP_003101203.1 256377543 8327653 complement(4025872..4027512) 1 NC_013093.1 PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: cti:RALTA_B1385 dipeptide ABC transporter atp_binding domain; ABC transporter 4027512 8327653 Amir_3463 Actinosynnema mirum DSM 43827 ABC transporter YP_003101203.1 4025872 R 446462 CDS YP_003101204.1 256377544 8327654 complement(4027509..4028390) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr6084 ABC transporter, permease; ABC transporter inner membrane protein 4028390 8327654 Amir_3464 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003101204.1 4027509 R 446462 CDS YP_003101205.1 256377545 8327655 complement(4028387..4029346) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr6083 ABC transporter, permease; ABC transporter inner membrane protein 4029346 8327655 Amir_3465 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003101205.1 4028387 R 446462 CDS YP_003101206.1 256377546 8327656 complement(4029343..4031133) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: mlo:mlr6082 ABC transporter, binding protein component; family 5 extracellular solute-binding protein 4031133 8327656 Amir_3466 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003101206.1 4029343 R 446462 CDS YP_003101207.1 256377547 8327657 4031227..4032054 1 NC_013093.1 PFAM: peptidase M55 D-aminopeptidase; KEGG: mrd:Mrad2831_3239 peptidase M55 D- aminopeptidase; peptidase M55 D-aminopeptidase 4032054 8327657 Amir_3467 Actinosynnema mirum DSM 43827 peptidase M55 D-aminopeptidase YP_003101207.1 4031227 D 446462 CDS YP_003101208.1 256377548 8327658 4032060..4033346 1 NC_013093.1 PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: dal:Dalk_4445 peptidase M20; hypothetical protein 4033346 8327658 Amir_3468 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101208.1 4032060 D 446462 CDS YP_003101209.1 256377549 8327659 4033460..4034665 1 NC_013093.1 hypothetical protein 4034665 8327659 Amir_3469 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101209.1 4033460 D 446462 CDS YP_003101210.1 256377550 8327660 4034802..4035797 1 NC_013093.1 KEGG: sml:Smlt2568 LacI-family transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 4035797 8327660 Amir_3470 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003101210.1 4034802 D 446462 CDS YP_003101211.1 256377551 8327661 4035802..4036626 1 NC_013093.1 KEGG: scl:sce1247 hypothetical protein; hypothetical protein 4036626 8327661 Amir_3471 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101211.1 4035802 D 446462 CDS YP_003101212.1 256377552 8327662 4036682..4037923 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: bur:Bcep18194_C6933 ABC sugar transporter, periplasmic ligand binding protein; family 1 extracellular solute-binding protein 4037923 8327662 Amir_3472 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003101212.1 4036682 D 446462 CDS YP_003101213.1 256377553 8327663 4037927..4038796 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bur:Bcep18194_C6934 ABC sugar transporter, inner membrane subunit; ABC transporter inner membrane protein 4038796 8327663 Amir_3473 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003101213.1 4037927 D 446462 CDS YP_003101214.1 256377554 8327664 4038790..4039632 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bur:Bcep18194_C6935 ABC sugar transporter, inner membrane subunit; ABC transporter inner membrane protein 4039632 8327664 Amir_3474 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003101214.1 4038790 D 446462 CDS YP_003101215.1 256377555 8327665 complement(4039808..4041025) 1 NC_013093.1 PFAM: integrase family protein; KEGG: gme:Gmet_1427 tyrosine recombinase XerD subunit; integrase family protein 4041025 8327665 Amir_3475 Actinosynnema mirum DSM 43827 integrase family protein YP_003101215.1 4039808 R 446462 CDS YP_003101216.1 256377556 8327666 4041194..4042273 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4042273 8327666 Amir_3476 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101216.1 4041194 D 446462 CDS YP_003101217.1 256377557 8327667 complement(4042404..4044617) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: scl:sce3873 WD repeat-containing protein; XRE family transcriptional regulator 4044617 8327667 Amir_3477 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101217.1 4042404 R 446462 CDS YP_003101218.1 256377558 8327668 4044754..4045824 1 NC_013093.1 PFAM: esterase; KEGG: mxa:MXAN_4935 esterase; esterase 4045824 8327668 Amir_3478 Actinosynnema mirum DSM 43827 esterase YP_003101218.1 4044754 D 446462 CDS YP_003101219.1 256377559 8327669 complement(4045880..4047280) 1 NC_013093.1 KEGG: bcj:BCAS0321a hypothetical protein; hypothetical protein 4047280 8327669 Amir_3479 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101219.1 4045880 R 446462 CDS YP_003101220.1 256377560 8327670 complement(4047277..4047582) 1 NC_013093.1 hypothetical protein 4047582 8327670 Amir_3480 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101220.1 4047277 R 446462 CDS YP_003101221.1 256377561 8327671 complement(4047579..4047977) 1 NC_013093.1 hypothetical protein 4047977 8327671 Amir_3481 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101221.1 4047579 R 446462 CDS YP_003101222.1 256377562 8327672 complement(4047974..4048744) 1 NC_013093.1 KEGG: pzu:PHZ_c2693 cytochrome C-type biogenesis protein CycH; cytochrome C biogenesis protein CycH 4048744 8327672 Amir_3482 Actinosynnema mirum DSM 43827 cytochrome C biogenesis protein CycH YP_003101222.1 4047974 R 446462 CDS YP_003101223.1 256377563 8327673 complement(4048741..4049082) 1 NC_013093.1 hypothetical protein 4049082 8327673 Amir_3483 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101223.1 4048741 R 446462 CDS YP_003101224.1 256377564 8327674 complement(4049079..4050230) 1 NC_013093.1 KEGG: scl:sce3028 protein kinase; hypothetical protein 4050230 8327674 Amir_3484 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101224.1 4049079 R 446462 CDS YP_003101225.1 256377565 8327675 4050544..4051353 1 NC_013093.1 KEGG: pau:PA14_07050 hypothetical protein; hypothetical protein 4051353 8327675 Amir_3485 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101225.1 4050544 D 446462 CDS YP_003101226.1 256377566 8327676 complement(4051350..4052294) 1 NC_013093.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: scl:sce5223 DeoR family transcriptional regulator; Helix-turn-helix type 11 domain-containing protein 4052294 8327676 Amir_3486 Actinosynnema mirum DSM 43827 Helix-turn-helix type 11 domain-containing protein YP_003101226.1 4051350 R 446462 CDS YP_003101227.1 256377567 8327677 4052376..4053401 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: rle:RL2983 aldo/keto reductase; aldo/keto reductase 4053401 8327677 Amir_3487 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101227.1 4052376 D 446462 CDS YP_003101228.1 256377568 8327678 4053409..4054476 1 NC_013093.1 KEGG: afw:Anae109_3510 hypothetical protein; hypothetical protein 4054476 8327678 Amir_3488 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101228.1 4053409 D 446462 CDS YP_003101229.1 256377569 8327679 complement(4054712..4055314) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: gdi:GDI2777 transcription regulator; TetR family transcriptional regulator 4055314 8327679 Amir_3489 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101229.1 4054712 R 446462 CDS YP_003101230.1 256377570 8327680 4055365..4056312 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bid:Bind_1477 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 4056312 8327680 Amir_3490 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003101230.1 4055365 D 446462 CDS YP_003101231.1 256377571 8327681 complement(4056605..4056979) 1 NC_013093.1 hypothetical protein 4056979 8327681 Amir_3491 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101231.1 4056605 R 446462 CDS YP_003101232.1 256377572 8327682 4057238..4057711 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: bba:Bd2755 ATP/GTP-binding protein; NUDIX hydrolase 4057711 8327682 Amir_3492 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003101232.1 4057238 D 446462 CDS YP_003101233.1 256377573 8327683 complement(4057749..4058150) 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: mch:Mchl_5535 endoribonuclease L-PSP; endoribonuclease L-PSP 4058150 8327683 Amir_3493 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003101233.1 4057749 R 446462 CDS YP_003101234.1 256377574 8327684 4058258..4059292 1 NC_013093.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: mxa:MXAN_2553 hypothetical protein; Helix-turn-helix type 11 domain-containing protein 4059292 8327684 Amir_3494 Actinosynnema mirum DSM 43827 Helix-turn-helix type 11 domain-containing protein YP_003101234.1 4058258 D 446462 CDS YP_003101235.1 256377575 8327685 4059367..4060854 1 NC_013093.1 PFAM: cellulose-binding family II; lipolytic protein G-D-S-L family; SMART: cellulose-binding family II; KEGG: ccs:CCNA_02538 endoglucanase E; cellulose-binding family protein 4060854 8327685 Amir_3495 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003101235.1 4059367 D 446462 CDS YP_003101236.1 256377576 8327686 complement(4061059..4061430) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: hha:Hhal_0914 transcriptional regulator, MerR family; MerR family transcriptional regulator 4061430 8327686 Amir_3496 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003101236.1 4061059 R 446462 CDS YP_003101237.1 256377577 8327687 complement(4062172..4062855) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcj:BCAM0093 MerR family regulatory protein; MerR family transcriptional regulator 4062855 8327687 Amir_3497 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003101237.1 4062172 R 446462 CDS YP_003101238.1 256377578 8327688 4062978..4064102 1 NC_013093.1 PFAM: erythromycin esterase; KEGG: swi:Swit_1817 erythromycin esterase; erythromycin esterase 4064102 8327688 Amir_3498 Actinosynnema mirum DSM 43827 erythromycin esterase YP_003101238.1 4062978 D 446462 CDS YP_003101239.1 256377579 8327689 complement(4064164..4064673) 1 NC_013093.1 hypothetical protein 4064673 8327689 Amir_3499 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101239.1 4064164 R 446462 CDS YP_003101240.1 256377580 8327690 complement(4064808..4065212) 1 NC_013093.1 KEGG: aeh:Mlg_0162 hypothetical protein; hypothetical protein 4065212 8327690 Amir_3500 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101240.1 4064808 R 446462 CDS YP_003101241.1 256377581 8327691 4065312..4066679 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: scl:sce2734 ubiquinone/menaquinone biosynthesis methyltransferase UbiE; type 12 methyltransferase 4066679 8327691 Amir_3501 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003101241.1 4065312 D 446462 CDS YP_003101242.1 256377582 8327692 4066679..4069183 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: scl:sce2733 bis(5'-nucleosyl)- tetraphosphatase (symmetrical); metallophosphoesterase 4069183 8327692 Amir_3502 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003101242.1 4066679 D 446462 CDS YP_003101243.1 256377583 8327693 4069250..4069828 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: scl:sce2276 hypothetical protein; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 4069828 8327693 Amir_3503 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003101243.1 4069250 D 446462 CDS YP_003101244.1 256377584 8327694 complement(4069869..4071416) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: scl:sce4973 monooxygenase; FAD-binding monooxygenase 4071416 8327694 Amir_3504 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101244.1 4069869 R 446462 CDS YP_003101245.1 256377585 8327695 4071577..4072098 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: dac:Daci_5761 hypothetical protein; hypothetical protein 4072098 8327695 Amir_3505 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101245.1 4071577 D 446462 CDS YP_003101246.1 256377586 8327696 complement(4072095..4072832) 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: azc:AZC_0786 ICC protein; metallophosphoesterase 4072832 8327696 Amir_3506 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003101246.1 4072095 R 446462 CDS YP_003101247.1 256377587 8327697 4072942..4074201 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4074201 8327697 Amir_3507 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101247.1 4072942 D 446462 CDS YP_003101248.1 256377588 8327698 4074198..4075157 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: bcy:Bcer98_0541 extracellular solute-binding protein; family 3 extracellular solute-binding protein 4075157 8327698 Amir_3508 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003101248.1 4074198 D 446462 CDS YP_003101249.1 256377589 8327699 4075249..4078284 1 NC_013093.1 PFAM: tyrosine protein kinase; SMART: serine/threonine protein kinase; KEGG: scl:sce1432 protein kinase; serine/threonine protein kinase 4078284 8327699 Amir_3509 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003101249.1 4075249 D 446462 CDS YP_003101250.1 256377590 8327700 4078281..4079252 1 NC_013093.1 PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: xau:Xaut_0996 protein phosphatase 2C-like protein; protein serine/threonine phosphatase 4079252 8327700 Amir_3510 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003101250.1 4078281 D 446462 CDS YP_003101251.1 256377591 8327701 4079400..4079885 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: cti:RALTA_A0035 transcriptional regulator, MarR family; MarR family transcriptional regulator 4079885 8327701 Amir_3511 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003101251.1 4079400 D 446462 CDS YP_003101252.1 256377592 8327702 4080150..4081301 1 NC_013093.1 KEGG: rpt:Rpal_0425 cytochrome P450; cytochrome P450-like protein 4081301 8327702 Amir_3512 Actinosynnema mirum DSM 43827 cytochrome P450-like protein YP_003101252.1 4080150 D 446462 CDS YP_003101253.1 256377593 8327705 complement(4082150..4083100) 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 4083100 8327705 Amir_3515 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003101253.1 4082150 R 446462 CDS YP_003101254.1 256377594 8327706 complement(4083149..4084171) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pla:Plav_0381 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 4084171 8327706 Amir_3516 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003101254.1 4083149 R 446462 CDS YP_003101255.1 256377595 8327707 complement(4084280..4085197) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mpt:Mpe_A3662 AraC family transcriptional regulator; AraC family transcriptional regulator 4085197 8327707 Amir_3517 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101255.1 4084280 R 446462 CDS YP_003101256.1 256377596 8327708 complement(4085194..4089114) 1 NC_013093.1 KEGG: ses:SARI_01345 ATP-dependent RNA helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; protein of unknown function DUF1605; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; ATPase AAA; ATP-dependent helicase HrpA 4089114 8327708 Amir_3518 Actinosynnema mirum DSM 43827 ATP-dependent helicase HrpA YP_003101256.1 4085194 R 446462 CDS YP_003101257.1 256377597 8327709 complement(4089281..4090030) 1 NC_013093.1 KEGG: cvi:CV_0390 hypothetical protein; hypothetical protein 4090030 8327709 Amir_3519 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101257.1 4089281 R 446462 CDS YP_003101258.1 256377598 8327710 4090116..4090481 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bja:blr4238 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase 4090481 8327710 Amir_3520 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003101258.1 4090116 D 446462 CDS YP_003101259.1 256377599 8327711 complement(4090920..4091606) 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: met:M446_2115 phosphoglycerate mutase; phosphoglycerate mutase 4091606 8327711 Amir_3521 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003101259.1 4090920 R 446462 CDS YP_003101260.1 256377600 8327712 complement(4091743..4092567) 1 NC_013093.1 KEGG: atc:AGR_C_1833 undecaprenyl-diphosphatase; TIGRFAM: undecaprenol kinase; PFAM: Bacitracin resistance protein BacA; undecaprenol kinase 4092567 8327712 Amir_3522 Actinosynnema mirum DSM 43827 undecaprenol kinase YP_003101260.1 4091743 R 446462 CDS YP_003101261.1 256377601 8327713 complement(4092564..4093613) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: pzu:PHZ_c2543 5,10- methylenetetrahydromethanopterin reductase; luciferase-like monooxygenase 4093613 8327713 Amir_3523 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003101261.1 4092564 R 446462 CDS YP_003101262.1 256377602 8327714 4093675..4094640 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: scl:sce4235 oxidoreductase; aldo/keto reductase 4094640 8327714 Amir_3524 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101262.1 4093675 D 446462 CDS YP_003101263.1 256377603 8327715 complement(4094704..4095945) 1 NC_013093.1 KEGG: FAP75; flagellar associated protein; hypothetical protein 4095945 8327715 Amir_3525 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101263.1 4094704 R 446462 CDS YP_003101264.1 256377604 8327716 4096111..4097076 1 NC_013093.1 KEGG: scl:sce2139 hypothetical protein; hypothetical protein 4097076 8327716 Amir_3526 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101264.1 4096111 D 446462 CDS YP_003101265.1 256377605 8327717 4097073..4097303 1 NC_013093.1 hypothetical protein 4097303 8327717 Amir_3527 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101265.1 4097073 D 446462 CDS YP_003101266.1 256377606 8327718 complement(4097670..4098797) 1 NC_013093.1 PFAM: protein of unknown function DUF450; KEGG: pmy:Pmen_3692 hypothetical protein; hypothetical protein 4098797 8327718 Amir_3528 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101266.1 4097670 R 446462 CDS YP_003101267.1 256377607 8327719 4099050..4099529 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rpd:RPD_1351 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 4099529 8327719 Amir_3529 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101267.1 4099050 D 446462 CDS YP_003101268.1 256377608 8327720 complement(4099768..4100571) 1 NC_013093.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: scl:sce6697 transcriptional regulator; TetR family transcriptional regulator 4100571 8327720 Amir_3530 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101268.1 4099768 R 446462 CDS YP_003101269.1 256377609 8327721 4100650..4102914 1 NC_013093.1 PFAM: ABC transporter; KEGG: scl:sce6315 excinuclease ABC subunit A; ABC transporter 4102914 8327721 Amir_3531 Actinosynnema mirum DSM 43827 ABC transporter YP_003101269.1 4100650 D 446462 CDS YP_003101270.1 256377610 8327722 4103007..4103780 1 NC_013093.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; siderophore-interacting protein; KEGG: mxa:MXAN_3639 iron-chelator utilization protein; FAD-binding 9 siderophore-interacting domain-containing protein 4103780 8327722 Amir_3532 Actinosynnema mirum DSM 43827 FAD-binding 9 siderophore-interacting domain-containing protein YP_003101270.1 4103007 D 446462 CDS YP_003101271.1 256377611 8327723 complement(4103936..4107130) 1 NC_013093.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; hypothetical protein; SMART: regulatory protein LuxR; KEGG: SNF2 superfamily protein; LuxR family transcriptional regulator 4107130 8327723 Amir_3533 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101271.1 4103936 R 446462 CDS YP_003101272.1 256377612 8327724 4107893..4108639 1 NC_013093.1 PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: lch:Lcho_2886 IclR family transcriptional regulator; IclR family transcriptional regulator 4108639 8327724 Amir_3534 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003101272.1 4107893 D 446462 CDS YP_003101273.1 256377613 8327725 4108709..4109452 1 NC_013093.1 hypothetical protein 4109452 8327725 Amir_3535 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101273.1 4108709 D 446462 CDS YP_003101274.1 256377614 8327726 4109560..4110729 1 NC_013093.1 PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: hypothetical protein; cellulose-binding family protein 4110729 8327726 Amir_3536 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003101274.1 4109560 D 446462 CDS YP_003101275.1 256377615 8327727 4110841..4111917 1 NC_013093.1 PFAM: Ricin B lectin; lipolytic protein G-D-S-L family; SMART: Ricin B lectin; KEGG: hypothetical protein; Ricin B lectin 4111917 8327727 Amir_3537 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101275.1 4110841 D 446462 CDS YP_003101276.1 256377616 8327728 4112009..4112995 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bsu:BSU27440 glutamine ABC transporter (glutamine-binding protein); family 3 extracellular solute-binding protein 4112995 8327728 Amir_3538 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003101276.1 4112009 D 446462 CDS YP_003101277.1 256377617 8327729 4113000..4114049 1 NC_013093.1 hypothetical protein 4114049 8327729 Amir_3539 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101277.1 4113000 D 446462 CDS YP_003101278.1 256377618 8327730 complement(4114114..4114485) 1 NC_013093.1 hypothetical protein 4114485 8327730 Amir_3540 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101278.1 4114114 R 446462 CDS YP_003101279.1 256377619 8327731 4114612..4115649 1 NC_013093.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: sil:SPO3307 saccharopine dehydrogenase; alanine dehydrogenase/PNT domain-containing protein 4115649 8327731 Amir_3541 Actinosynnema mirum DSM 43827 alanine dehydrogenase/PNT domain-containing protein YP_003101279.1 4114612 D 446462 CDS YP_003101280.1 256377620 8327732 4115642..4116790 1 NC_013093.1 PFAM: saccharopine dehydrogenase; 6- phosphogluconate dehydrogenase NAD-binding; KEGG: sit:TM1040_0106 saccharopine dehydrogenase (NADP+, L-glutamate forming); saccharopine dehydrogenase 4116790 8327732 Amir_3542 Actinosynnema mirum DSM 43827 saccharopine dehydrogenase YP_003101280.1 4115642 D 446462 CDS YP_003101281.1 256377621 8327734 4117655..4119286 1 NC_013093.1 KEGG: scl:sce3550 hypothetical protein; hypothetical protein 4119286 8327734 Amir_3544 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101281.1 4117655 D 446462 CDS YP_003101282.1 256377622 8327735 complement(4119289..4119915) 1 NC_013093.1 PFAM: uracil-DNA glycosylase; KEGG: met:M446_1657 uracil-DNA glycosylase protein; uracil-DNA glycosylase 4119915 8327735 Amir_3545 Actinosynnema mirum DSM 43827 uracil-DNA glycosylase YP_003101282.1 4119289 R 446462 CDS YP_003101283.1 256377623 8327736 complement(4120025..4120546) 1 NC_013093.1 hypothetical protein 4120546 8327736 Amir_3546 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101283.1 4120025 R 446462 CDS YP_003101284.1 256377624 8327737 4120859..4122058 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: atc:AGR_C_1839 hypothetical protein; major facilitator superfamily protein 4122058 8327737 Amir_3547 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101284.1 4120859 D 446462 CDS YP_003101285.1 256377625 8327738 4122135..4122650 1 NC_013093.1 hypothetical protein 4122650 8327738 Amir_3548 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101285.1 4122135 D 446462 CDS YP_003101286.1 256377626 8327739 complement(4122661..4123149) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mrd:Mrad2831_3652 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 4123149 8327739 Amir_3549 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101286.1 4122661 R 446462 CDS YP_003101287.1 256377627 8327740 4123340..4124458 1 NC_013093.1 PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; KEGG: hypothetical protein; glycoside hydrolase family protein 4124458 8327740 Amir_3550 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101287.1 4123340 D 446462 CDS YP_003101288.1 256377628 8327741 complement(4124841..4126031) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 4126031 8327741 Amir_3551 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003101288.1 4124841 R 446462 CDS YP_003101289.1 256377629 8327742 complement(4126140..4127087) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: predicted protein; alpha/beta hydrolase fold protein 4127087 8327742 Amir_3552 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101289.1 4126140 R 446462 CDS YP_003101290.1 256377630 8327743 4127299..4129158 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: rru:Rru_A2348 glycosyl transferase; family 2 glycosyl transferase 4129158 8327743 Amir_3553 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003101290.1 4127299 D 446462 CDS YP_003101291.1 256377631 8327744 4129182..4130693 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA2757 benzoate-CoA ligase; AMP-dependent synthetase and ligase 4130693 8327744 Amir_3554 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101291.1 4129182 D 446462 CDS YP_003101292.1 256377632 8327745 4130785..4131129 1 NC_013093.1 hypothetical protein 4131129 8327745 Amir_3555 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101292.1 4130785 D 446462 CDS YP_003101293.1 256377633 8327746 complement(4131145..4131780) 1 NC_013093.1 hypothetical protein 4131780 8327746 Amir_3556 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101293.1 4131145 R 446462 CDS YP_003101294.1 256377634 8327747 complement(4131830..4132297) 1 NC_013093.1 hypothetical protein 4132297 8327747 Amir_3557 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101294.1 4131830 R 446462 CDS YP_003101295.1 256377635 8327748 4132426..4132929 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: xau:Xaut_0976 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 4132929 8327748 Amir_3558 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003101295.1 4132426 D 446462 CDS YP_003101296.1 256377636 8327749 4132926..4133984 1 NC_013093.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bha:BH3670 attenuator for lytABC and LytR expression; cell envelope-related transcriptional attenuator 4133984 8327749 Amir_3559 Actinosynnema mirum DSM 43827 cell envelope-related transcriptional attenuator YP_003101296.1 4132926 D 446462 CDS YP_003101297.1 256377637 8327751 4134452..4135474 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: alkanal monooxygenase (bacterial liciferase alpha chain) like protein; luciferase-like monooxygenase 4135474 8327751 Amir_3561 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003101297.1 4134452 D 446462 CDS YP_003101298.1 256377638 8327752 complement(4135526..4136509) 1 NC_013093.1 PFAM: Bile acid:sodium symporter; KEGG: gox:GOX0688 efflux protein; Bile acid:sodium symporter 4136509 8327752 Amir_3562 Actinosynnema mirum DSM 43827 Bile acid:sodium symporter YP_003101298.1 4135526 R 446462 CDS YP_003101299.1 256377639 8327753 4136642..4137565 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: smt:Smal_1721 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 4137565 8327753 Amir_3563 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003101299.1 4136642 D 446462 CDS YP_003101300.1 256377640 8327754 4137794..4140976 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: shn:Shewana3_1740 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 4140976 8327754 Amir_3564 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003101300.1 4137794 D 446462 CDS YP_003101301.1 256377641 8327755 complement(4141041..4141610) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 4141610 8327755 Amir_3565 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101301.1 4141041 R 446462 CDS YP_003101302.1 256377642 8327756 4141708..4142667 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: hne:HNE_2225 aldo/keto reductase family oxidoreductase; aldo/keto reductase 4142667 8327756 Amir_3566 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101302.1 4141708 D 446462 CDS YP_003101303.1 256377643 8327757 4142749..4143657 1 NC_013093.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bur:Bcep18194_B0145 esterase/lipase/thioesterase; alpha/beta hydrolase fold-3 domain-containing protein 4143657 8327757 Amir_3567 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold-3 domain-containing protein YP_003101303.1 4142749 D 446462 CDS YP_003101304.1 256377644 8327758 complement(4143668..4144876) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce0310 acetyltransferase; GCN5-like N-acetyltransferase 4144876 8327758 Amir_3568 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101304.1 4143668 R 446462 CDS YP_003101305.1 256377645 8327759 4145071..4146525 1 NC_013093.1 PFAM: glycoside hydrolase family 43; glycosyl hydrolase family 32 domain protein; KEGG: pzu:PHZ_c2480 xylosidase/arabinosidase; glycoside hydrolase family protein 4146525 8327759 Amir_3569 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101305.1 4145071 D 446462 CDS YP_003101306.1 256377646 8327760 complement(4146737..4147120) 1 NC_013093.1 hypothetical protein 4147120 8327760 Amir_3570 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101306.1 4146737 R 446462 CDS YP_003101307.1 256377647 8327761 4147372..4150236 1 NC_013093.1 PFAM: transcriptional activator domain; hypothetical protein; NB-ARC domain protein; transcriptional regulator domain protein; SMART: hypothetical protein; KEGG: scl:sce6858 hypothetical protein; SARP family transcriptional regulator 4150236 8327761 Amir_3571 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003101307.1 4147372 D 446462 CDS YP_003101308.1 256377648 8327762 complement(4150285..4150695) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4150695 8327762 Amir_3572 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101308.1 4150285 R 446462 CDS YP_003101309.1 256377649 8327763 complement(4150843..4151412) 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: afw:Anae109_0915 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 4151412 8327763 Amir_3573 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101309.1 4150843 R 446462 CDS YP_003101310.1 256377650 8327764 complement(4151424..4152044) 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_0902 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator 4152044 8327764 Amir_3574 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101310.1 4151424 R 446462 CDS YP_003101311.1 256377651 8327765 complement(4152347..4153597) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: gbm:Gbem_1224 major facilitator superfamily MFS_1; major facilitator superfamily protein 4153597 8327765 Amir_3575 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101311.1 4152347 R 446462 CDS YP_003101312.1 256377652 8327766 complement(4153726..4155045) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: scl:sce0675 cytochrome P450 CYP267A1; cytochrome P450 4155045 8327766 Amir_3576 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101312.1 4153726 R 446462 CDS YP_003101313.1 256377653 8327767 complement(4155042..4162280) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3618 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 4162280 8327767 Amir_3577 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101313.1 4155042 R 446462 CDS YP_003101314.1 256377654 8327768 complement(4162304..4168600) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3636 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 4168600 8327768 Amir_3578 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101314.1 4162304 R 446462 CDS YP_003101315.1 256377655 8327769 4168784..4168987 1 NC_013093.1 PFAM: MbtH domain protein; KEGG: scl:sce3255 hypothetical protein; MbtH domain-containing protein 4168987 8327769 Amir_3579 Actinosynnema mirum DSM 43827 MbtH domain-containing protein YP_003101315.1 4168784 D 446462 CDS YP_003101316.1 256377656 8327770 4169016..4171337 1 NC_013093.1 PFAM: Lantibiotic dehydratase domain protein; KEGG: scl:sce2385 hypothetical protein; Lantibiotic dehydratase domain-containing protein 4171337 8327770 Amir_3580 Actinosynnema mirum DSM 43827 Lantibiotic dehydratase domain-containing protein YP_003101316.1 4169016 D 446462 CDS YP_003101317.1 256377657 8327771 4171337..4172803 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_1089 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein 4172803 8327771 Amir_3581 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101317.1 4171337 D 446462 CDS YP_003101318.1 256377658 8327772 4172800..4174209 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_3217 pyridoxal-5'-phosphate- dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit 4174209 8327772 Amir_3582 Actinosynnema mirum DSM 43827 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003101318.1 4172800 D 446462 CDS YP_003101319.1 256377659 8327774 4174459..4176744 1 NC_013093.1 PFAM: Lantibiotic dehydratase domain protein; KEGG: scl:sce2385 hypothetical protein; Lantibiotic dehydratase domain-containing protein 4176744 8327774 Amir_3584 Actinosynnema mirum DSM 43827 Lantibiotic dehydratase domain-containing protein YP_003101319.1 4174459 D 446462 CDS YP_003101320.1 256377660 8327775 4176860..4177807 1 NC_013093.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: ornithine cyclodeaminase; ornithine cyclodeaminase/mu-crystallin 4177807 8327775 Amir_3585 Actinosynnema mirum DSM 43827 ornithine cyclodeaminase/mu-crystallin YP_003101320.1 4176860 D 446462 CDS YP_003101321.1 256377661 8327776 4177869..4178378 1 NC_013093.1 hypothetical protein 4178378 8327776 Amir_3586 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101321.1 4177869 D 446462 CDS YP_003101322.1 256377662 8327777 4178482..4178610 1 NC_013093.1 hypothetical protein 4178610 8327777 Amir_3587 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101322.1 4178482 D 446462 CDS YP_003101323.1 256377663 8327778 4178673..4179194 1 NC_013093.1 KEGG: mxa:MXAN_2219 hypothetical protein; hypothetical protein 4179194 8327778 Amir_3588 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101323.1 4178673 D 446462 CDS YP_003101324.1 256377664 8327779 4179449..4180147 1 NC_013093.1 TIGRFAM: cobalamin biosynthesis protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: glo:Glov_3660 cobalamin biosynthesis protein CbiM; cobalamin biosynthesis protein CbiM 4180147 8327779 Amir_3589 Actinosynnema mirum DSM 43827 cobalamin biosynthesis protein CbiM YP_003101324.1 4179449 D 446462 CDS YP_003101325.1 256377665 8327780 4180140..4180496 1 NC_013093.1 PFAM: cobalt transport protein CbiN; KEGG: kpn:KPN_03187 cobalt transport protein CbiN; cobalt transport protein CbiN 4180496 8327780 Amir_3590 Actinosynnema mirum DSM 43827 cobalt transport protein CbiN YP_003101325.1 4180140 D 446462 CDS YP_003101326.1 256377666 8327781 4180498..4181265 1 NC_013093.1 TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; KEGG: mag:amb0277 ABC-type cobalt transport system; cobalt ABC transporter inner membrane protein 4181265 8327781 Amir_3591 Actinosynnema mirum DSM 43827 cobalt ABC transporter inner membrane protein YP_003101326.1 4180498 D 446462 CDS YP_003101327.1 256377667 8327782 4181262..4182077 1 NC_013093.1 KEGG: mag:amb0278 ABC-type cobalt transport system; TIGRFAM: cobalt ABC transporter ATPase; PFAM: ABC transporter; SMART: ATPase AAA; cobalt ABC transporter ATPase 4182077 8327782 Amir_3592 Actinosynnema mirum DSM 43827 cobalt ABC transporter ATPase YP_003101327.1 4181262 D 446462 CDS YP_003101328.1 256377668 8327783 complement(4182111..4182653) 1 NC_013093.1 KEGG: bbt:BBta_2404 hypothetical protein; hypothetical protein 4182653 8327783 Amir_3593 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101328.1 4182111 R 446462 CDS YP_003101329.1 256377669 8327784 complement(4182747..4183583) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: azc:AZC_1457 transcriptional regulator; MerR family transcriptional regulator 4183583 8327784 Amir_3594 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003101329.1 4182747 R 446462 CDS YP_003101330.1 256377670 8327785 4183752..4185341 1 NC_013093.1 KEGG: bha:BH1072 hypothetical protein; PucR family transcriptional regulator 4185341 8327785 Amir_3595 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003101330.1 4183752 D 446462 CDS YP_003101331.1 256377671 8327786 4185503..4186777 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: xca:xccb100_1581 D-amino-acid dehydrogenase; FAD dependent oxidoreductase 4186777 8327786 Amir_3596 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003101331.1 4185503 D 446462 CDS YP_003101332.1 256377672 8327787 4186874..4187341 1 NC_013093.1 PFAM: transcription elongation factor GreA/GreB domain protein; GreA/GreB family elongation factor 4187341 8327787 Amir_3597 Actinosynnema mirum DSM 43827 GreA/GreB family elongation factor YP_003101332.1 4186874 D 446462 CDS YP_003101333.1 256377673 8327788 complement(4187453..4187641) 1 NC_013093.1 hypothetical protein 4187641 8327788 Amir_3598 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101333.1 4187453 R 446462 CDS YP_003101334.1 256377674 8327789 complement(4187625..4188377) 1 NC_013093.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: scl:sce2341 hypothetical protein; Activator of Hsp90 ATPase 1 family protein 4188377 8327789 Amir_3599 Actinosynnema mirum DSM 43827 Activator of Hsp90 ATPase 1 family protein YP_003101334.1 4187625 R 446462 CDS YP_003101335.1 256377675 8327790 complement(4188414..4189622) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: scl:sce0675 cytochrome P450 CYP267A1; cytochrome P450 4189622 8327790 Amir_3600 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101335.1 4188414 R 446462 CDS YP_003101336.1 256377676 8327791 complement(4189619..4189840) 1 NC_013093.1 PFAM: MbtH domain protein; KEGG: bcy:Bcer98_1759 MbtH domain-containing protein; MbtH domain-containing protein 4189840 8327791 Amir_3601 Actinosynnema mirum DSM 43827 MbtH domain-containing protein YP_003101336.1 4189619 R 446462 CDS YP_003101337.1 256377677 8327792 complement(4189882..4214517) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; methyltransferase type 11; methyltransferase type 12; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: smd:Smed_6472 amino acid adenylation domain; cyclic nucleotide-binding protein 4214517 8327792 Amir_3602 Actinosynnema mirum DSM 43827 cyclic nucleotide-binding protein YP_003101337.1 4189882 R 446462 CDS YP_003101338.1 256377678 8327793 complement(4214919..4217807) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: neu:NE0720 ABC transporter permease/ATP- binding protein; ABC transporter 4217807 8327793 Amir_3603 Actinosynnema mirum DSM 43827 ABC transporter YP_003101338.1 4214919 R 446462 CDS YP_003101339.1 256377679 8327794 complement(4217877..4218215) 1 NC_013093.1 KEGG: nmu:Nmul_A0032 hypothetical protein; hypothetical protein 4218215 8327794 Amir_3604 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101339.1 4217877 R 446462 CDS YP_003101340.1 256377680 8327795 4218854..4219345 1 NC_013093.1 KEGG: mex:Mext_0734 hypothetical protein; hypothetical protein 4219345 8327795 Amir_3605 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101340.1 4218854 D 446462 CDS YP_003101341.1 256377681 8327796 complement(4219418..4220605) 1 NC_013093.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sfu:Sfum_2453 serine phosphatase; protein serine/threonine phosphatase 4220605 8327796 Amir_3606 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003101341.1 4219418 R 446462 CDS YP_003101342.1 256377682 8327797 4220767..4221246 1 NC_013093.1 hypothetical protein 4221246 8327797 Amir_3607 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101342.1 4220767 D 446462 CDS YP_003101343.1 256377683 8327798 complement(4221253..4222173) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: ade:Adeh_0027 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4222173 8327798 Amir_3608 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003101343.1 4221253 R 446462 CDS YP_003101344.1 256377684 8327799 4222273..4222959 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mes:Meso_0701 transcriptional regulator, TetR family; TetR family transcriptional regulator 4222959 8327799 Amir_3609 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101344.1 4222273 D 446462 CDS YP_003101345.1 256377685 8327800 4223112..4225286 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: thuE; trehalosemaltose ABC transporter; family 1 extracellular solute-binding protein 4225286 8327800 Amir_3610 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003101345.1 4223112 D 446462 CDS YP_003101346.1 256377686 8327801 complement(4225342..4227852) 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: hha:Hhal_1416 protein of unknown function DUF214; hypothetical protein 4227852 8327801 Amir_3611 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101346.1 4225342 R 446462 CDS YP_003101347.1 256377687 8327802 complement(4227852..4228547) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: shl:Shal_1616 lipoprotein releasing system, ATP-binding protein; ABC transporter 4228547 8327802 Amir_3612 Actinosynnema mirum DSM 43827 ABC transporter YP_003101347.1 4227852 R 446462 CDS YP_003101348.1 256377688 8327803 complement(4228544..4230241) 1 NC_013093.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_5165 GMC oxidoreductase family protein; glucose-methanol-choline oxidoreductase 4230241 8327803 Amir_3613 Actinosynnema mirum DSM 43827 glucose-methanol-choline oxidoreductase YP_003101348.1 4228544 R 446462 CDS YP_003101349.1 256377689 8327804 complement(4230238..4230708) 1 NC_013093.1 PFAM: cyclase/dehydrase; KEGG: psp:PSPPH_4312 hypothetical protein; cyclase/dehydrase 4230708 8327804 Amir_3614 Actinosynnema mirum DSM 43827 cyclase/dehydrase YP_003101349.1 4230238 R 446462 CDS YP_003101350.1 256377690 8327805 complement(4230722..4232002) 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: esa:ESA_03492 putrescine--2-oxoglutarate aminotransferase; class III aminotransferase 4232002 8327805 Amir_3615 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003101350.1 4230722 R 446462 CDS YP_003101351.1 256377691 8327806 complement(4232161..4233291) 1 NC_013093.1 KEGG: bph:Bphy_6313 isobutylamine N-hydroxylase; isobutylamine N-hydroxylase 4233291 8327806 Amir_3616 Actinosynnema mirum DSM 43827 isobutylamine N-hydroxylase YP_003101351.1 4232161 R 446462 CDS YP_003101352.1 256377692 8327807 complement(4233288..4234934) 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: pca:Pcar_1701 aldehyde dehydrogenase, NAD- linked; aldehyde dehydrogenase 4234934 8327807 Amir_3617 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003101352.1 4233288 R 446462 CDS YP_003101353.1 256377693 8327808 complement(4234968..4235915) 1 NC_013093.1 KEGG: plu:plu4388 hypothetical protein; hypothetical protein 4235915 8327808 Amir_3618 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101353.1 4234968 R 446462 CDS YP_003101354.1 256377694 8327809 complement(4235952..4236938) 1 NC_013093.1 PFAM: protein of unknown function DUF470; protein of unknown function DUF472; protein of unknown function DUF471; KEGG: bph:Bphy_6311 hypothetical protein; hypothetical protein 4236938 8327809 Amir_3619 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101354.1 4235952 R 446462 CDS YP_003101355.1 256377695 8327810 complement(4236935..4237429) 1 NC_013093.1 KEGG: bph:Bphy_6310 integral membrane protein; integral membrane protein 4237429 8327810 Amir_3620 Actinosynnema mirum DSM 43827 integral membrane protein YP_003101355.1 4236935 R 446462 CDS YP_003101356.1 256377696 8327811 complement(4237596..4239299) 1 NC_013093.1 KEGG: kpe:KPK_3424 hypothetical protein; hypothetical protein 4239299 8327811 Amir_3621 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101356.1 4237596 R 446462 CDS YP_003101357.1 256377697 8327812 complement(4239296..4240201) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: hch:HCH_00758 alpha/beta hydrolase; alpha/beta hydrolase fold protein 4240201 8327812 Amir_3622 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101357.1 4239296 R 446462 CDS YP_003101358.1 256377698 8327813 4240640..4242430 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: acp:A2cp1_1619 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 4242430 8327813 Amir_3623 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101358.1 4240640 D 446462 CDS YP_003101359.1 256377699 8327814 complement(4242477..4243025) 1 NC_013093.1 KEGG: bac:BamMC406_2852 hexapaptide repeat- containing transferase; hexapaptide repeat-containing transferase 4243025 8327814 Amir_3624 Actinosynnema mirum DSM 43827 hexapaptide repeat-containing transferase YP_003101359.1 4242477 R 446462 CDS YP_003101360.1 256377700 8327815 4243108..4244037 1 NC_013093.1 PFAM: regulatory protein LysR; KEGG: mxa:MXAN_5480 transcriptional regulator, LysR family; LysR family transcriptional regulator 4244037 8327815 Amir_3625 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003101360.1 4243108 D 446462 CDS YP_003101361.1 256377701 8327816 4244077..4244553 1 NC_013093.1 KEGG: nar:Saro_3714 hypothetical protein; hypothetical protein 4244553 8327816 Amir_3626 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101361.1 4244077 D 446462 CDS YP_003101362.1 256377702 8327817 4244590..4244919 1 NC_013093.1 hypothetical protein 4244919 8327817 Amir_3627 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101362.1 4244590 D 446462 CDS YP_003101363.1 256377703 8327818 complement(4244938..4245333) 1 NC_013093.1 hypothetical protein 4245333 8327818 Amir_3628 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101363.1 4244938 R 446462 CDS YP_003101364.1 256377704 8327819 4245567..4246841 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: dac:Daci_3577 major facilitator transporter; major facilitator superfamily protein 4246841 8327819 Amir_3629 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101364.1 4245567 D 446462 CDS YP_003101365.1 256377705 8327820 4246895..4247770 1 NC_013093.1 PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: mmr:Mmar10_1955 methyltransferase type 11; type 11 methyltransferase 4247770 8327820 Amir_3630 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003101365.1 4246895 D 446462 CDS YP_003101366.1 256377706 8327821 4247811..4248650 1 NC_013093.1 hypothetical protein 4248650 8327821 Amir_3631 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101366.1 4247811 D 446462 CDS YP_003101367.1 256377707 8327822 complement(4248762..4249604) 1 NC_013093.1 hypothetical protein 4249604 8327822 Amir_3632 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101367.1 4248762 R 446462 CDS YP_003101368.1 256377708 8327825 4251529..4252179 1 NC_013093.1 hypothetical protein 4252179 8327825 Amir_3635 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101368.1 4251529 D 446462 CDS YP_003101369.1 256377709 8327826 4252350..4252796 1 NC_013093.1 hypothetical protein 4252796 8327826 Amir_3636 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101369.1 4252350 D 446462 CDS YP_003101370.1 256377710 8327827 4252777..4254678 1 NC_013093.1 KEGG: bbr:BB2304 competence protein; hypothetical protein 4254678 8327827 Amir_3637 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101370.1 4252777 D 446462 CDS YP_003101371.1 256377711 8327828 complement(4254939..4255286) 1 NC_013093.1 KEGG: gbm:Gbem_2481 hypothetical protein; hypothetical protein 4255286 8327828 Amir_3638 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101371.1 4254939 R 446462 CDS YP_003101372.1 256377712 8327829 complement(4255283..4256830) 1 NC_013093.1 hypothetical protein 4256830 8327829 Amir_3639 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101372.1 4255283 R 446462 CDS YP_003101373.1 256377713 8327831 4257471..4257653 1 NC_013093.1 hypothetical protein 4257653 8327831 Amir_3641 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101373.1 4257471 D 446462 CDS YP_003101374.1 256377714 8327832 4257650..4257967 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 4257967 8327832 Amir_3642 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003101374.1 4257650 D 446462 CDS YP_003101375.1 256377715 8327833 4257997..4258284 1 NC_013093.1 hypothetical protein 4258284 8327833 Amir_3643 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101375.1 4257997 D 446462 CDS YP_003101376.1 256377716 8327835 4258904..4260931 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: pha:PSHAb0091 cell divisionFtsK/SpoIIIE domain-containing protein; cell division protein FtsK/SpoIIIE 4260931 8327835 Amir_3645 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003101376.1 4258904 D 446462 CDS YP_003101377.1 256377717 8327836 complement(4260993..4261898) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 4261898 8327836 Amir_3646 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003101377.1 4260993 R 446462 CDS YP_003101378.1 256377718 8327837 complement(4261895..4262167) 1 NC_013093.1 hypothetical protein 4262167 8327837 Amir_3647 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101378.1 4261895 R 446462 CDS YP_003101379.1 256377719 8327838 4262325..4263176 1 NC_013093.1 SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 4263176 8327838 Amir_3648 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101379.1 4262325 D 446462 CDS YP_003101380.1 256377720 8327839 4263218..4263445 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 4263445 8327839 Amir_3649 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101380.1 4263218 D 446462 CDS YP_003101381.1 256377721 8327840 4263636..4265021 1 NC_013093.1 KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein 4265021 8327840 Amir_3650 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101381.1 4263636 D 446462 CDS YP_003101382.1 256377722 8327841 complement(4265024..4265683) 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hypothetical protein; HAD superfamily hydrolase 4265683 8327841 Amir_3651 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003101382.1 4265024 R 446462 CDS YP_003101383.1 256377723 8327842 4266080..4266694 1 NC_013093.1 hypothetical protein 4266694 8327842 Amir_3652 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101383.1 4266080 D 446462 CDS YP_003101384.1 256377724 8327843 complement(4266640..4267470) 1 NC_013093.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: rru:Rru_A2021 endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 4267470 8327843 Amir_3653 Actinosynnema mirum DSM 43827 endonuclease/exonuclease/phosphatase YP_003101384.1 4266640 R 446462 CDS YP_003101385.1 256377725 8327844 complement(4267467..4268519) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: ecp:ECP_1719 oxidoreductase YdjG; aldo/keto reductase 4268519 8327844 Amir_3654 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101385.1 4267467 R 446462 CDS YP_003101386.1 256377726 8327845 4268681..4270816 1 NC_013093.1 PFAM: Radical SAM domain protein; KEGG: rpb:RPB_2074 radical SAM binding protein; Radical SAM domain-containing protein 4270816 8327845 Amir_3655 Actinosynnema mirum DSM 43827 Radical SAM domain-containing protein YP_003101386.1 4268681 D 446462 CDS YP_003101387.1 256377727 8327846 4270966..4271193 1 NC_013093.1 hypothetical protein 4271193 8327846 Amir_3656 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101387.1 4270966 D 446462 CDS YP_003101388.1 256377728 8327847 4271244..4271564 1 NC_013093.1 hypothetical protein 4271564 8327847 Amir_3657 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101388.1 4271244 D 446462 CDS YP_003101389.1 256377729 8327848 4271933..4272751 1 NC_013093.1 hypothetical protein 4272751 8327848 Amir_3658 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101389.1 4271933 D 446462 CDS YP_003101390.1 256377730 8327849 4272803..4273645 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 4273645 8327849 Amir_3659 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003101390.1 4272803 D 446462 CDS YP_003101391.1 256377731 8327851 complement(4275175..4276341) 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: sal:Sala_1921 glycosyl transferase, group 1; group 1 glycosyl transferase 4276341 8327851 Amir_3661 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003101391.1 4275175 R 446462 CDS YP_003101392.1 256377732 8327852 complement(4276470..4277714) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 4277714 8327852 Amir_3662 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101392.1 4276470 R 446462 CDS YP_003101393.1 256377733 8327853 complement(4277795..4278673) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cak:Caul_3937 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 4278673 8327853 Amir_3663 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101393.1 4277795 R 446462 CDS YP_003101394.1 256377734 8327854 complement(4278732..4280087) 1 NC_013093.1 TIGRFAM: crotonyl-CoA reductase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: dds:Ddes_1332 crotonyl-CoA reductase; crotonyl-CoA reductase 4280087 8327854 Amir_3664 Actinosynnema mirum DSM 43827 crotonyl-CoA reductase YP_003101394.1 4278732 R 446462 CDS YP_003101395.1 256377735 8327855 complement(4280158..4281126) 1 NC_013093.1 PFAM: aspartyl/Asparaginyl beta-hydroxylase; KEGG: similar to aspartyl/asparaginyl beta- hydroxylase; peptide-aspartate beta-dioxygenase 4281126 8327855 Amir_3665 Actinosynnema mirum DSM 43827 peptide-aspartate beta-dioxygenase YP_003101395.1 4280158 R 446462 CDS YP_003101396.1 256377736 8327856 complement(4281123..4281722) 1 NC_013093.1 PFAM: Ankyrin; SMART: Ankyrin; KEGG: Os03g0655500; hypothetical protein; Ankyrin 4281722 8327856 Amir_3666 Actinosynnema mirum DSM 43827 Ankyrin YP_003101396.1 4281123 R 446462 CDS YP_003101397.1 256377737 8327857 complement(4281712..4283565) 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: pca:Pcar_1259 ATP-binding transport protein; multicopy suppressor of HtrB; ABC transporter 4283565 8327857 Amir_3667 Actinosynnema mirum DSM 43827 ABC transporter YP_003101397.1 4281712 R 446462 CDS YP_003101398.1 256377738 8327858 complement(4283562..4284515) 1 NC_013093.1 PFAM: aspartyl/Asparaginyl beta-hydroxylase; KEGG: hypothetical protein; peptide-aspartate beta-dioxygenase 4284515 8327858 Amir_3668 Actinosynnema mirum DSM 43827 peptide-aspartate beta-dioxygenase YP_003101398.1 4283562 R 446462 CDS YP_003101399.1 256377739 8327859 complement(4284512..4285978) 1 NC_013093.1 TIGRFAM: cytidyltransferase-related domain protein; PFAM: PfkB domain protein; cytidylyltransferase; KEGG: nmu:Nmul_A1792 bifunctional ADP-heptose synthase; cytidyltransferase 4285978 8327859 Amir_3669 Actinosynnema mirum DSM 43827 cytidyltransferase YP_003101399.1 4284512 R 446462 CDS YP_003101400.1 256377740 8327860 complement(4286007..4287632) 1 NC_013093.1 PFAM: carbamoyltransferase; KEGG: bra:BRADO2235 carbamoyltransferase family protein; carbamoyltransferase 4287632 8327860 Amir_3670 Actinosynnema mirum DSM 43827 carbamoyltransferase YP_003101400.1 4286007 R 446462 CDS YP_003101401.1 256377741 8327861 complement(4287629..4288771) 1 NC_013093.1 PFAM: glycosyl transferase family 9; KEGG: rso:RSc0565 ADP-heptose--lipopolysaccharide heptosyltransferase II protein; glycosyl transferase family protein 4288771 8327861 Amir_3671 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003101401.1 4287629 R 446462 CDS YP_003101402.1 256377742 8327862 complement(4288803..4289390) 1 NC_013093.1 PFAM: MbtH domain protein; KEGG: bbt:BBta_1084 hypothetical protein; MbtH domain-containing protein 4289390 8327862 Amir_3672 Actinosynnema mirum DSM 43827 MbtH domain-containing protein YP_003101402.1 4288803 R 446462 CDS YP_003101403.1 256377743 8327863 complement(4289471..4290478) 1 NC_013093.1 PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: pen:PSEEN3233 SyrP protein; taurine catabolism dioxygenase TauD/TfdA 4290478 8327863 Amir_3673 Actinosynnema mirum DSM 43827 taurine catabolism dioxygenase TauD/TfdA YP_003101403.1 4289471 R 446462 CDS YP_003101404.1 256377744 8327864 complement(4290517..4293099) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; nitroreductase; phosphopantetheine-binding; KEGG: pen:PSEEN2716 non-ribosomal peptide synthetase; AMP-dependent synthetase and ligase 4293099 8327864 Amir_3674 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101404.1 4290517 R 446462 CDS YP_003101405.1 256377745 8327865 complement(4293096..4300955) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; Non-ribosomal peptide synthetase; condensation domain protein; KEGG: psb:Psyr_1792 amino acid adenylation; amino acid adenylation domain-containing protein 4300955 8327865 Amir_3675 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101405.1 4293096 R 446462 CDS YP_003101406.1 256377746 8327866 complement(4300948..4302864) 1 NC_013093.1 KEGG: bbt:BBta_3705 asparagine synthase, glutamine- hydrolyzing; TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; asparagine synthase 4302864 8327866 Amir_3676 Actinosynnema mirum DSM 43827 asparagine synthase YP_003101406.1 4300948 R 446462 CDS YP_003101407.1 256377747 8327867 complement(4302870..4304597) 1 NC_013093.1 PFAM: aspartyl/Asparaginyl beta-hydroxylase; KEGG: hypothetical protein; aspartyl/Asparaginyl beta-hydroxylase 4304597 8327867 Amir_3677 Actinosynnema mirum DSM 43827 aspartyl/Asparaginyl beta-hydroxylase YP_003101407.1 4302870 R 446462 CDS YP_003101408.1 256377748 8327868 complement(4304594..4305583) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: aba:Acid345_0895 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4305583 8327868 Amir_3678 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003101408.1 4304594 R 446462 CDS YP_003101409.1 256377749 8327869 complement(4305580..4307388) 1 NC_013093.1 PFAM: condensation domain protein; phosphopantetheine-binding; KEGG: peptide synthetase; condensation domain-containing protein 4307388 8327869 Amir_3679 Actinosynnema mirum DSM 43827 condensation domain-containing protein YP_003101409.1 4305580 R 446462 CDS YP_003101410.1 256377750 8327870 complement(4307375..4315540) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein 4315540 8327870 Amir_3680 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101410.1 4307375 R 446462 CDS YP_003101411.1 256377751 8327871 complement(4315537..4318965) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: eca:ECA1487 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 4318965 8327871 Amir_3681 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101411.1 4315537 R 446462 CDS YP_003101412.1 256377752 8327872 complement(4318962..4323455) 1 NC_013093.1 PFAM: KR domain protein; beta-ketoacyl synthase; acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3631 polyketide synthase type I; KR domain-containing protein 4323455 8327872 Amir_3682 Actinosynnema mirum DSM 43827 KR domain-containing protein YP_003101412.1 4318962 R 446462 CDS YP_003101413.1 256377753 8327873 complement(4323452..4326631) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3636 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 4326631 8327873 Amir_3683 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101413.1 4323452 R 446462 CDS YP_003101414.1 256377754 8327874 complement(4326640..4332969) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein 4332969 8327874 Amir_3684 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101414.1 4326640 R 446462 CDS YP_003101415.1 256377755 8327875 complement(4333280..4335754) 1 NC_013093.1 PFAM: peptidase S45 penicillin amidase; KEGG: mxa:MXAN_2906 penicillin acylase family protein; peptidase S45 penicillin amidase 4335754 8327875 Amir_3685 Actinosynnema mirum DSM 43827 peptidase S45 penicillin amidase YP_003101415.1 4333280 R 446462 CDS YP_003101416.1 256377756 8327876 complement(4335932..4337947) 1 NC_013093.1 PFAM: condensation domain protein; KEGG: reh:H16_B1685 non-ribosomal peptide synthetase; condensation domain-containing protein 4337947 8327876 Amir_3686 Actinosynnema mirum DSM 43827 condensation domain-containing protein YP_003101416.1 4335932 R 446462 CDS YP_003101417.1 256377757 8327877 complement(4338052..4338342) 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: mlo:mlr2600 hypothetical protein; HxlR family transcriptional regulator 4338342 8327877 Amir_3687 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003101417.1 4338052 R 446462 CDS YP_003101418.1 256377758 8327879 complement(4340739..4341683) 1 NC_013093.1 KEGG: bmv:BMASAVP1_0867 RemN protein; RemN protein 4341683 8327879 Amir_3689 Actinosynnema mirum DSM 43827 RemN protein YP_003101418.1 4340739 R 446462 CDS YP_003101419.1 256377759 8327880 4342081..4342254 1 NC_013093.1 hypothetical protein 4342254 8327880 Amir_3690 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101419.1 4342081 D 446462 CDS YP_003101420.1 256377760 8327881 4342380..4342895 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 4342895 8327881 Amir_3691 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003101420.1 4342380 D 446462 CDS YP_003101421.1 256377761 8327882 4343043..4344236 1 NC_013093.1 PFAM: cytochrome P450; KEGG: hypothetical protein; cytochrome P450 4344236 8327882 Amir_3692 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101421.1 4343043 D 446462 CDS YP_003101422.1 256377762 8327883 4344233..4344430 1 NC_013093.1 PFAM: protein of unknown function DUF1271; KEGG: bha:BH1605 ferredoxin; hypothetical protein 4344430 8327883 Amir_3693 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101422.1 4344233 D 446462 CDS YP_003101423.1 256377763 8327884 complement(4344444..4344896) 1 NC_013093.1 KEGG: dsh:Dshi_1841 hypothetical protein; hypothetical protein 4344896 8327884 Amir_3694 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101423.1 4344444 R 446462 CDS YP_003101424.1 256377764 8327885 4345073..4346884 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bpa:BPP2159 ABC transporter, ATP-binding protein; ABC transporter 4346884 8327885 Amir_3695 Actinosynnema mirum DSM 43827 ABC transporter YP_003101424.1 4345073 D 446462 CDS YP_003101425.1 256377765 8327886 complement(4346913..4347566) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 4347566 8327886 Amir_3696 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101425.1 4346913 R 446462 CDS YP_003101426.1 256377766 8327887 complement(4347563..4348504) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 4348504 8327887 Amir_3697 Actinosynnema mirum DSM 43827 histidine kinase YP_003101426.1 4347563 R 446462 CDS YP_003101427.1 256377767 8327888 complement(4348510..4349940) 1 NC_013093.1 PFAM: beta-lactamase; KEGG: bat:BAS2400 penicillin-binding protein; beta-lactamase 4349940 8327888 Amir_3698 Actinosynnema mirum DSM 43827 beta-lactamase YP_003101427.1 4348510 R 446462 CDS YP_003101428.1 256377768 8327889 4350093..4351208 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: gdj:Gdia_2837 monooxygenase FAD-binding; FAD-binding monooxygenase 4351208 8327889 Amir_3699 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101428.1 4350093 D 446462 CDS YP_003101429.1 256377769 8327890 complement(4351254..4351814) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: acp:A2cp1_1650 regulatory protein TetR; TetR family transcriptional regulator 4351814 8327890 Amir_3700 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101429.1 4351254 R 446462 CDS YP_003101430.1 256377770 8327891 4351972..4352391 1 NC_013093.1 KEGG: nar:Saro_3538 hypothetical protein; hypothetical protein 4352391 8327891 Amir_3701 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101430.1 4351972 D 446462 CDS YP_003101431.1 256377771 8327892 complement(4352474..4353997) 1 NC_013093.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: smd:Smed_0363 protein of unknown function DUF112 transmembrane; hypothetical protein 4353997 8327892 Amir_3702 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101431.1 4352474 R 446462 CDS YP_003101432.1 256377772 8327893 complement(4353990..4354484) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4354484 8327893 Amir_3703 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101432.1 4353990 R 446462 CDS YP_003101433.1 256377773 8327894 complement(4354481..4355467) 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: azc:AZC_4334 hypothetical protein; hypothetical protein 4355467 8327894 Amir_3704 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101433.1 4354481 R 446462 CDS YP_003101434.1 256377774 8327895 4355612..4357195 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: sfu:Sfum_3991 signal transduction histidine kinase regulating citrate/malate metabolism; signal transduction histidine kinase regulating citrate/malate metabolism 4357195 8327895 Amir_3705 Actinosynnema mirum DSM 43827 signal transduction histidine kinase regulating citrate/malate metabolism YP_003101434.1 4355612 D 446462 CDS YP_003101435.1 256377775 8327896 4357198..4357878 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: vco:VC0395_A1209 response regulator; response regulator receiver and unknown domain-containing protein 4357878 8327896 Amir_3706 Actinosynnema mirum DSM 43827 response regulator receiver and unknown domain-containing protein YP_003101435.1 4357198 D 446462 CDS YP_003101436.1 256377776 8327897 complement(4357920..4358309) 1 NC_013093.1 PFAM: YCII-related; KEGG: scl:sce5148 hypothetical protein; YCII-like protein 4358309 8327897 Amir_3707 Actinosynnema mirum DSM 43827 YCII-like protein YP_003101436.1 4357920 R 446462 CDS YP_003101437.1 256377777 8327898 complement(4358375..4359940) 1 NC_013093.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: rsq:Rsph17025_2978 alpha amylase, catalytic region; alpha amylase catalytic subunit 4359940 8327898 Amir_3708 Actinosynnema mirum DSM 43827 alpha amylase catalytic subunit YP_003101437.1 4358375 R 446462 CDS YP_003101438.1 256377778 8327899 complement(4359937..4360914) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: mex:Mext_1273 dehydrogenase protein; luciferase-like monooxygenase 4360914 8327899 Amir_3709 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003101438.1 4359937 R 446462 CDS YP_003101439.1 256377779 8327900 complement(4360965..4361741) 1 NC_013093.1 SMART: ATPase AAA; KEGG: rme:Rmet_4896 SMC protein-like protein; ATPase AAA 4361741 8327900 Amir_3710 Actinosynnema mirum DSM 43827 ATPase AAA YP_003101439.1 4360965 R 446462 CDS YP_003101440.1 256377780 8327901 complement(4361845..4362468) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: tmz:Tmz1t_0804 transcriptional regulator, TetR family; TetR family transcriptional regulator 4362468 8327901 Amir_3711 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101440.1 4361845 R 446462 CDS YP_003101441.1 256377781 8327902 4362533..4363393 1 NC_013093.1 PFAM: ketopantoate reductase ApbA/PanE domain protein; KEGG: scl:sce9123 oxidoreductase; ketopantoate reductase ApbA/PanE domain-containing protein 4363393 8327902 Amir_3712 Actinosynnema mirum DSM 43827 ketopantoate reductase ApbA/PanE domain-containing protein YP_003101441.1 4362533 D 446462 CDS YP_003101442.1 256377782 8327903 complement(4363499..4363975) 1 NC_013093.1 KEGG: mno:Mnod_4965 hypothetical protein; hypothetical protein 4363975 8327903 Amir_3713 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101442.1 4363499 R 446462 CDS YP_003101443.1 256377783 8327904 4363995..4364531 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: baa:BA_3806 bacterial regulatory proteins, TetR family; TetR family transcriptional regulator 4364531 8327904 Amir_3714 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101443.1 4363995 D 446462 CDS YP_003101444.1 256377784 8327905 complement(4364612..4365190) 1 NC_013093.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: mxa:MXAN_5566 FxsA-like protein; FxsA cytoplasmic membrane protein 4365190 8327905 Amir_3715 Actinosynnema mirum DSM 43827 FxsA cytoplasmic membrane protein YP_003101444.1 4364612 R 446462 CDS YP_003101445.1 256377785 8327906 4365277..4366656 1 NC_013093.1 PFAM: Radical SAM domain protein; KEGG: mxa:MXAN_4699 L-lysine 2,3- aminomutase; lysine 2,3-aminomutase 4366656 8327906 Amir_3716 Actinosynnema mirum DSM 43827 lysine 2,3-aminomutase YP_003101445.1 4365277 D 446462 CDS YP_003101446.1 256377786 8327907 complement(4366905..4367285) 1 NC_013093.1 hypothetical protein 4367285 8327907 Amir_3717 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101446.1 4366905 R 446462 CDS YP_003101447.1 256377787 8327908 complement(4367305..4368297) 1 NC_013093.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: rle:pRL120701 transmembrane magnesium and cobalt transport protein; Mg2 transporter protein CorA family protein 4368297 8327908 Amir_3718 Actinosynnema mirum DSM 43827 Mg2 transporter protein CorA family protein YP_003101447.1 4367305 R 446462 CDS YP_003101448.1 256377788 8327909 4368359..4369042 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: lch:Lcho_0755 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 4369042 8327909 Amir_3719 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003101448.1 4368359 D 446462 CDS YP_003101449.1 256377789 8327910 4369177..4370028 1 NC_013093.1 hypothetical protein 4370028 8327910 Amir_3720 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101449.1 4369177 D 446462 CDS YP_003101450.1 256377790 8327911 4370025..4371839 1 NC_013093.1 KEGG: ade:Adeh_3311 hypothetical protein; hypothetical protein 4371839 8327911 Amir_3721 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101450.1 4370025 D 446462 CDS YP_003101451.1 256377791 8327912 4371836..4372927 1 NC_013093.1 hypothetical protein 4372927 8327912 Amir_3722 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101451.1 4371836 D 446462 CDS YP_003101452.1 256377792 8327913 complement(4372993..4373319) 1 NC_013093.1 hypothetical protein 4373319 8327913 Amir_3723 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101452.1 4372993 R 446462 CDS YP_003101453.1 256377793 8327914 4373506..4375314 1 NC_013093.1 KEGG: bha:BH2614 cytochrome Caa3 oxidase (subunit I); TIGRFAM: cytochrome C oxidase, subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase, subunit I 4375314 8327914 Amir_3724 Actinosynnema mirum DSM 43827 cytochrome C oxidase, subunit I YP_003101453.1 4373506 D 446462 CDS YP_003101454.1 256377794 8327915 4375763..4376827 1 NC_013093.1 KEGG: dac:Daci_4530 acyl protein synthase/acyl-CoA reductase-like protein; acyl protein synthase/acyl-CoA reductase-like protein 4376827 8327915 Amir_3725 Actinosynnema mirum DSM 43827 acyl protein synthase/acyl-CoA reductase-like protein YP_003101454.1 4375763 D 446462 CDS YP_003101455.1 256377795 8327916 4376831..4378306 1 NC_013093.1 PFAM: acyl-CoA reductase; KEGG: aav:Aave_4516 acyl-CoA reductase; acyl-CoA reductase 4378306 8327916 Amir_3726 Actinosynnema mirum DSM 43827 acyl-CoA reductase YP_003101455.1 4376831 D 446462 CDS YP_003101456.1 256377796 8327917 4378383..4380815 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6315 excinuclease ABC subunit A; ABC transporter 4380815 8327917 Amir_3727 Actinosynnema mirum DSM 43827 ABC transporter YP_003101456.1 4378383 D 446462 CDS YP_003101457.1 256377797 8327918 complement(4380886..4382163) 1 NC_013093.1 PFAM: dicarboxylate carrier MatC domain protein; Citrate transporter; KEGG: matC; dicarboxylate-carrier protein; dicarboxylate carrier MatC domain-containing protein 4382163 8327918 Amir_3728 Actinosynnema mirum DSM 43827 dicarboxylate carrier MatC domain-containing protein YP_003101457.1 4380886 R 446462 CDS YP_003101458.1 256377798 8327919 complement(4382160..4383482) 1 NC_013093.1 PFAM: SAF domain protein; homoserine dehydrogenase NAD-binding; KEGG: rru:Rru_A3141 homoserine dehydrogenase, NAD- binding; SAF domain-containing protein 4383482 8327919 Amir_3729 Actinosynnema mirum DSM 43827 SAF domain-containing protein YP_003101458.1 4382160 R 446462 CDS YP_003101459.1 256377799 8327920 4383621..4384874 1 NC_013093.1 PFAM: type III effector Hrp-dependent outers; KEGG: pde:Pden_3383 type III effector Hrp-dependent outers; Hrp-dependent type III effector protein 4384874 8327920 Amir_3730 Actinosynnema mirum DSM 43827 Hrp-dependent type III effector protein YP_003101459.1 4383621 D 446462 CDS YP_003101460.1 256377800 8327921 4384871..4385533 1 NC_013093.1 PFAM: class II aldolase/adducin family protein; KEGG: hiq:CGSHiGG_08670 aldolase; class II aldolase/adducin family protein 4385533 8327921 Amir_3731 Actinosynnema mirum DSM 43827 class II aldolase/adducin family protein YP_003101460.1 4384871 D 446462 CDS YP_003101461.1 256377801 8327922 4385538..4386389 1 NC_013093.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: psp:PSPPH_4844 DeoR family transcriptional regulator; DeoR family transcriptional regulator 4386389 8327922 Amir_3732 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003101461.1 4385538 D 446462 CDS YP_003101462.1 256377802 8327923 complement(4386386..4387201) 1 NC_013093.1 PFAM: Bifunctional DNA primase/polymerase; KEGG: bbt:BBta_1244 phage / plasmid primase P4; Bifunctional DNA primase/polymerase 4387201 8327923 Amir_3733 Actinosynnema mirum DSM 43827 Bifunctional DNA primase/polymerase YP_003101462.1 4386386 R 446462 CDS YP_003101463.1 256377803 8327924 complement(4387521..4388162) 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: mch:Mchl_5542 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 4388162 8327924 Amir_3734 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003101463.1 4387521 R 446462 CDS YP_003101464.1 256377804 8327925 complement(4388413..4389528) 1 NC_013093.1 PFAM: sodium/calcium exchanger membrane region; KEGG: bph:Bphy_3245 sodium/calcium exchanger membrane region; sodium/calcium exchanger membrane protein 4389528 8327925 Amir_3735 Actinosynnema mirum DSM 43827 sodium/calcium exchanger membrane protein YP_003101464.1 4388413 R 446462 CDS YP_003101465.1 256377805 8327926 4389753..4392806 1 NC_013093.1 KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein; PAS/PAC sensor protein 4392806 8327926 Amir_3736 Actinosynnema mirum DSM 43827 PAS/PAC sensor protein YP_003101465.1 4389753 D 446462 CDS YP_003101466.1 256377806 8327927 4392993..4395221 1 NC_013093.1 PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce3550 hypothetical protein; hypothetical protein 4395221 8327927 Amir_3737 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101466.1 4392993 D 446462 CDS YP_003101467.1 256377807 8327928 complement(4395246..4395611) 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1431 anti-anti-sigma factor family protein; anti-sigma-factor antagonist 4395611 8327928 Amir_3738 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003101467.1 4395246 R 446462 CDS YP_003101468.1 256377808 8327929 complement(4395709..4397280) 1 NC_013093.1 PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; KEGG: pfo:Pfl01_3138 multi-sensor hybrid histidine kinase; response regulator receiver modulated serine phosphatase 4397280 8327929 Amir_3739 Actinosynnema mirum DSM 43827 response regulator receiver modulated serine phosphatase YP_003101468.1 4395709 R 446462 CDS YP_003101469.1 256377809 8327930 complement(4397277..4399127) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_0803 histidine kinase; histidine kinase 4399127 8327930 Amir_3740 Actinosynnema mirum DSM 43827 histidine kinase YP_003101469.1 4397277 R 446462 CDS YP_003101470.1 256377810 8327931 complement(4399124..4400143) 1 NC_013093.1 PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; KEGG: mch:Mchl_3342 anti-sigma regulatory factor, serine/threonine protein kinase; anti-sigma regulatory factor, serine/threonine protein kinase 4400143 8327931 Amir_3741 Actinosynnema mirum DSM 43827 anti-sigma regulatory factor, serine/threonine protein kinase YP_003101470.1 4399124 R 446462 CDS YP_003101471.1 256377811 8327932 complement(4400145..4400558) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: xca:xccb100_3165 sigma-B negative effector; anti-sigma regulatory factor, serine/threonine protein kinase 4400558 8327932 Amir_3742 Actinosynnema mirum DSM 43827 anti-sigma regulatory factor, serine/threonine protein kinase YP_003101471.1 4400145 R 446462 CDS YP_003101472.1 256377812 8327933 complement(4400555..4400932) 1 NC_013093.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dac:Daci_4410 anti-sigma-factor antagonist; anti-sigma-factor antagonist 4400932 8327933 Amir_3743 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003101472.1 4400555 R 446462 CDS YP_003101473.1 256377813 8327934 complement(4400932..4401798) 1 NC_013093.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: xac:XAC1269 positive regulator of sigma-B; anti-sigma-factor antagonist 4401798 8327934 Amir_3744 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003101473.1 4400932 R 446462 CDS YP_003101474.1 256377814 8327935 complement(4402034..4402657) 1 NC_013093.1 KEGG: met:M446_0126 hypothetical protein; hypothetical protein 4402657 8327935 Amir_3745 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101474.1 4402034 R 446462 CDS YP_003101475.1 256377815 8327936 complement(4402828..4404501) 1 NC_013093.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: scl:sce0787 hypothetical protein; glucose-methanol-choline oxidoreductase 4404501 8327936 Amir_3746 Actinosynnema mirum DSM 43827 glucose-methanol-choline oxidoreductase YP_003101475.1 4402828 R 446462 CDS YP_003101476.1 256377816 8327937 complement(4404561..4406015) 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: bur:Bcep18194_B2514 lipolytic protein; FAD dependent oxidoreductase 4406015 8327937 Amir_3747 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003101476.1 4404561 R 446462 CDS YP_003101477.1 256377817 8327938 4406087..4407139 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pag:PLES_32251 transcriptional regulator; AraC family transcriptional regulator 4407139 8327938 Amir_3748 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101477.1 4406087 D 446462 CDS YP_003101478.1 256377818 8327939 complement(4407109..4407735) 1 NC_013093.1 KEGG: afw:Anae109_3301 hypothetical protein; hypothetical protein 4407735 8327939 Amir_3749 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101478.1 4407109 R 446462 CDS YP_003101479.1 256377819 8327940 4407930..4408889 1 NC_013093.1 PFAM: glycoside hydrolase family 43; KEGG: hypothetical protein; Arabinan endo-1,5-alpha-L-arabinosidase 4408889 8327940 Amir_3750 Actinosynnema mirum DSM 43827 Arabinan endo-1,5-alpha-L-arabinosidase YP_003101479.1 4407930 D 446462 CDS YP_003101480.1 256377820 8327943 4409326..4411908 1 NC_013093.1 KEGG: mxa:MXAN_5281 hypothetical protein; hypothetical protein 4411908 8327943 Amir_3751 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101480.1 4409326 D 446462 CDS YP_003101481.1 256377821 8327944 4412999..4413424 1 NC_013093.1 ECF subfamily RNA polymerase sigma-24 subunit 4413424 8327944 Amir_3752 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003101481.1 4412999 D 446462 CDS YP_003101482.1 256377822 8327945 4413522..4414262 1 NC_013093.1 hypothetical protein 4414262 8327945 Amir_3753 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101482.1 4413522 D 446462 CDS YP_003101483.1 256377823 8327946 complement(4414475..4416316) 1 NC_013093.1 PFAM: ABC transporter transmembrane protein; ABC transporter; SMART: ATPase AAA; KEGG: scl:sce5645 carbohydrate ABC transporter; ABC transporter transmembrane protein 4416316 8327946 Amir_3754 Actinosynnema mirum DSM 43827 ABC transporter transmembrane protein YP_003101483.1 4414475 R 446462 CDS YP_003101484.1 256377824 8327947 4417098..4417229 1 NC_013093.1 hypothetical protein 4417229 8327947 Amir_3755 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101484.1 4417098 D 446462 CDS YP_003101485.1 256377825 8327948 complement(4417761..4419506) 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: scl:sce5644 carbohydrate ABC transporter; ABC transporter 4419506 8327948 Amir_3756 Actinosynnema mirum DSM 43827 ABC transporter YP_003101485.1 4417761 R 446462 CDS YP_003101486.1 256377826 8327949 4419578..4420198 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: gdj:Gdia_1592 regulatory protein TetR; TetR family transcriptional regulator 4420198 8327949 Amir_3757 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101486.1 4419578 D 446462 CDS YP_003101487.1 256377827 8327950 complement(4420205..4421047) 1 NC_013093.1 KEGG: bcz:BCZK2871 hypothetical protein; hypothetical protein 4421047 8327950 Amir_3758 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101487.1 4420205 R 446462 CDS YP_003101488.1 256377828 8327951 complement(4421144..4421770) 1 NC_013093.1 hypothetical protein 4421770 8327951 Amir_3759 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101488.1 4421144 R 446462 CDS YP_003101489.1 256377829 8327953 4425066..4425890 1 NC_013093.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: dar:Daro_0364 ABC transporter; Hemerythrin HHE cation binding domain-containing protein 4425890 8327953 Amir_3761 Actinosynnema mirum DSM 43827 Hemerythrin HHE cation binding domain-containing protein YP_003101489.1 4425066 D 446462 CDS YP_003101490.1 256377830 8327954 complement(4425940..4427070) 1 NC_013093.1 PFAM: SpoOM family protein; KEGG: vha:VIBHAR_02077 hypothetical protein; SpoOM family protein 4427070 8327954 Amir_3762 Actinosynnema mirum DSM 43827 SpoOM family protein YP_003101490.1 4425940 R 446462 CDS YP_003101491.1 256377831 8327955 4427265..4427663 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: esa:ESA_01491 hypothetical protein; MerR family transcriptional regulator 4427663 8327955 Amir_3763 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003101491.1 4427265 D 446462 CDS YP_003101492.1 256377832 8327956 complement(4427736..4428965) 1 NC_013093.1 TIGRFAM: DGQHR domain protein; KEGG: spl:Spea_2305 hypothetical protein; DGQHR domain-containing protein 4428965 8327956 Amir_3764 Actinosynnema mirum DSM 43827 DGQHR domain-containing protein YP_003101492.1 4427736 R 446462 CDS YP_003101493.1 256377833 8327957 complement(4429110..4429751) 1 NC_013093.1 hypothetical protein 4429751 8327957 Amir_3765 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101493.1 4429110 R 446462 CDS YP_003101494.1 256377834 8327958 complement(4429822..4431537) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: afw:Anae109_0119 protein kinase; serine/threonine protein kinase 4431537 8327958 Amir_3766 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003101494.1 4429822 R 446462 CDS YP_003101495.1 256377835 8327959 4431792..4432877 1 NC_013093.1 TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: dac:Daci_0183 alcohol dehydrogenase; mycothiol-dependent formaldehyde dehydrogenase 4432877 8327959 Amir_3767 Actinosynnema mirum DSM 43827 mycothiol-dependent formaldehyde dehydrogenase YP_003101495.1 4431792 D 446462 CDS YP_003101496.1 256377836 8327960 4432874..4433503 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: glo:Glov_3342 beta-lactamase domain protein; beta-lactamase domain-containing protein 4433503 8327960 Amir_3768 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003101496.1 4432874 D 446462 CDS YP_003101497.1 256377837 8327961 complement(4433530..4434732) 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: sus:Acid_3087 TonB-dependent receptor; Ricin B lectin 4434732 8327961 Amir_3769 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101497.1 4433530 R 446462 CDS YP_003101498.1 256377838 8327962 4434884..4436146 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: dol:Dole_0353 major facilitator transporter; major facilitator superfamily protein 4436146 8327962 Amir_3770 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101498.1 4434884 D 446462 CDS YP_003101499.1 256377839 8327963 4436143..4437537 1 NC_013093.1 PFAM: pyridoxal-dependent decarboxylase; aminotransferase class V; KEGG: dal:Dalk_0154 pyridoxal-dependent decarboxylase; pyridoxal-dependent decarboxylase 4437537 8327963 Amir_3771 Actinosynnema mirum DSM 43827 pyridoxal-dependent decarboxylase YP_003101499.1 4436143 D 446462 CDS YP_003101500.1 256377840 8327964 4437608..4438915 1 NC_013093.1 KEGG: psb:Psyr_1929 hypothetical protein; hypothetical protein 4438915 8327964 Amir_3772 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101500.1 4437608 D 446462 CDS YP_003101501.1 256377841 8327965 complement(4438969..4440231) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bpd:BURPS668_A2325 major facilitator superfamily permease; major facilitator superfamily protein 4440231 8327965 Amir_3773 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101501.1 4438969 R 446462 CDS YP_003101502.1 256377842 8327966 4440361..4441194 1 NC_013093.1 hypothetical protein 4441194 8327966 Amir_3774 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101502.1 4440361 D 446462 CDS YP_003101503.1 256377843 8327967 4441205..4441531 1 NC_013093.1 hypothetical protein 4441531 8327967 Amir_3775 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101503.1 4441205 D 446462 CDS YP_003101504.1 256377844 8327968 4441528..4442028 1 NC_013093.1 hypothetical protein 4442028 8327968 Amir_3776 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101504.1 4441528 D 446462 CDS YP_003101505.1 256377845 8327970 4442542..4442988 1 NC_013093.1 hypothetical protein 4442988 8327970 Amir_3778 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101505.1 4442542 D 446462 CDS YP_003101506.1 256377846 8327971 complement(4443040..4443453) 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3- methyltransferase; KEGG: xca:xccb100_3974 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase 4443453 8327971 Amir_3779 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003101506.1 4443040 R 446462 CDS YP_003101507.1 256377847 8327972 4443559..4443681 1 NC_013093.1 hypothetical protein 4443681 8327972 Amir_3780 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101507.1 4443559 D 446462 CDS YP_003101508.1 256377848 8327973 complement(4443794..4444210) 1 NC_013093.1 KEGG: mgm:Mmc1_3605 MJ0042 family finger-like protein; hypothetical protein 4444210 8327973 Amir_3781 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101508.1 4443794 R 446462 CDS YP_003101509.1 256377849 8327974 complement(4444548..4444967) 1 NC_013093.1 hypothetical protein 4444967 8327974 Amir_3782 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101509.1 4444548 R 446462 CDS YP_003101510.1 256377850 8327975 4445068..4445277 1 NC_013093.1 hypothetical protein 4445277 8327975 Amir_3783 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101510.1 4445068 D 446462 CDS YP_003101511.1 256377851 8327977 4445777..4446466 1 NC_013093.1 hypothetical protein 4446466 8327977 Amir_3785 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101511.1 4445777 D 446462 CDS YP_003101512.1 256377852 8327978 complement(4446474..4447148) 1 NC_013093.1 PFAM: FR47 domain protein; GCN5-related N- acetyltransferase; KEGG: swi:Swit_4396 GCN5-related N- acetyltransferase; FR47 domain-containing protein 4447148 8327978 Amir_3786 Actinosynnema mirum DSM 43827 FR47 domain-containing protein YP_003101512.1 4446474 R 446462 CDS YP_003101513.1 256377853 8327979 4447288..4447614 1 NC_013093.1 hypothetical protein 4447614 8327979 Amir_3787 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101513.1 4447288 D 446462 CDS YP_003101514.1 256377854 8327980 complement(4447658..4447924) 1 NC_013093.1 hypothetical protein 4447924 8327980 Amir_3788 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101514.1 4447658 R 446462 CDS YP_003101515.1 256377855 8327981 complement(4448254..4449111) 1 NC_013093.1 KEGG: bbr:BB0423 hydrolase; hydrolase 4449111 8327981 Amir_3789 Actinosynnema mirum DSM 43827 hydrolase YP_003101515.1 4448254 R 446462 CDS YP_003101516.1 256377856 8327982 complement(4449111..4449611) 1 NC_013093.1 hypothetical protein 4449611 8327982 Amir_3790 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101516.1 4449111 R 446462 CDS YP_003101517.1 256377857 8327983 complement(4449621..4449737) 1 NC_013093.1 hypothetical protein 4449737 8327983 Amir_3791 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101517.1 4449621 R 446462 CDS YP_003101518.1 256377858 8327984 4450200..4451207 1 NC_013093.1 KEGG: impN; serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial; hypothetical protein 4451207 8327984 Amir_3792 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101518.1 4450200 D 446462 CDS YP_003101519.1 256377859 8327985 4451209..4452192 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4452192 8327985 Amir_3793 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101519.1 4451209 D 446462 CDS YP_003101520.1 256377860 8327986 4452176..4453609 1 NC_013093.1 KEGG: rec:RHECIAT_CH0004205 adenylosuccinate synthase protein; PFAM: adenylosuccinate synthetase; SMART: adenylosuccinate synthetase; adenylosuccinate synthase 4453609 8327986 Amir_3794 Actinosynnema mirum DSM 43827 adenylosuccinate synthase YP_003101520.1 4452176 D 446462 CDS YP_003101521.1 256377861 8327987 4453680..4454366 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: aeh:Mlg_0745 NUDIX hydrolase; NUDIX hydrolase 4454366 8327987 Amir_3795 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003101521.1 4453680 D 446462 CDS YP_003101522.1 256377862 8327988 4454686..4456479 1 NC_013093.1 PFAM: Ricin B lectin; glycoside hydrolase clan GH- D; SMART: Ricin B lectin; KEGG: cak:Caul_2129 alpha-galactosidase; Ricin B lectin 4456479 8327988 Amir_3796 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101522.1 4454686 D 446462 CDS YP_003101523.1 256377863 8327989 4456583..4456993 1 NC_013093.1 KEGG: sde:Sde_1986 hypothetical protein; hypothetical protein 4456993 8327989 Amir_3797 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101523.1 4456583 D 446462 CDS YP_003101524.1 256377864 8327990 complement(4457237..4458805) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 4458805 8327990 Amir_3798 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003101524.1 4457237 R 446462 CDS YP_003101525.1 256377865 8327991 4459388..4459819 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: bur:Bcep18194_A4724 HxlR family transcriptional regulator; HxlR family transcriptional regulator 4459819 8327991 Amir_3799 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003101525.1 4459388 D 446462 CDS YP_003101526.1 256377866 8327992 4460082..4461833 1 NC_013093.1 PFAM: transketolase; transketolase; KEGG: tgr:Tgr7_0832 1-deoxy-D-xylulose-5-phosphate synthase; transketolase 4461833 8327992 Amir_3800 Actinosynnema mirum DSM 43827 transketolase YP_003101526.1 4460082 D 446462 CDS YP_003101527.1 256377867 8327993 4461830..4462822 1 NC_013093.1 KEGG: scl:sce8552 terpene cyclase; hypothetical protein 4462822 8327993 Amir_3801 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101527.1 4461830 D 446462 CDS YP_003101528.1 256377868 8327994 4462943..4463590 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4463590 8327994 Amir_3802 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101528.1 4462943 D 446462 CDS YP_003101529.1 256377869 8327996 4464116..4464541 1 NC_013093.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: cvi:CV_3487 hypothetical protein; BadM/Rrf2 family transcriptional regulator 4464541 8327996 Amir_3804 Actinosynnema mirum DSM 43827 BadM/Rrf2 family transcriptional regulator YP_003101529.1 4464116 D 446462 CDS YP_003101530.1 256377870 8327997 4464555..4465778 1 NC_013093.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; globin; oxidoreductase FAD-binding domain protein; KEGG: rso:RSc3398 flavohemoprotein (hemoglobin- like) transmembrane; oxidoreductase FAD/NAD(P)-binding domain-containing protein 4465778 8327997 Amir_3805 Actinosynnema mirum DSM 43827 oxidoreductase FAD/NAD(P)-binding domain-containing protein YP_003101530.1 4464555 D 446462 CDS YP_003101531.1 256377871 8327998 complement(4465978..4466982) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: aav:Aave_2096 transcriptional regulator, ArsR family; ArsR family transcriptional regulator 4466982 8327998 Amir_3806 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003101531.1 4465978 R 446462 CDS YP_003101532.1 256377872 8327999 complement(4467254..4467676) 1 NC_013093.1 PFAM: Roadblock/LC7 family protein; KEGG: sml:Smlt4270 hypothetical protein; Roadblock/LC7 family protein 4467676 8327999 Amir_3807 Actinosynnema mirum DSM 43827 Roadblock/LC7 family protein YP_003101532.1 4467254 R 446462 CDS YP_003101533.1 256377873 8328000 complement(4467673..4468041) 1 NC_013093.1 KEGG: sml:Smlt4269 hypothetical protein; hypothetical protein 4468041 8328000 Amir_3808 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101533.1 4467673 R 446462 CDS YP_003101534.1 256377874 8328001 complement(4468230..4469708) 1 NC_013093.1 TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0895 phytoene desaturase; phytoene desaturase 4469708 8328001 Amir_3809 Actinosynnema mirum DSM 43827 phytoene desaturase YP_003101534.1 4468230 R 446462 CDS YP_003101535.1 256377875 8328002 complement(4469828..4470913) 1 NC_013093.1 PFAM: polyprenyl synthetase; KEGG: scl:sce4204 geranyltranstransferase; polyprenyl synthetase 4470913 8328002 Amir_3810 Actinosynnema mirum DSM 43827 polyprenyl synthetase YP_003101535.1 4469828 R 446462 CDS YP_003101536.1 256377876 8328003 4471084..4472016 1 NC_013093.1 PFAM: squalene/phytoene synthase; KEGG: PSY; PSY (PHYTOENE SYNTHASE); geranylgeranyl- diphosphate geranylgeranyltransferase; K02291 phytoene synthase; squalene/phytoene synthase 4472016 8328003 Amir_3811 Actinosynnema mirum DSM 43827 squalene/phytoene synthase YP_003101536.1 4471084 D 446462 CDS YP_003101537.1 256377877 8328004 4472135..4473112 1 NC_013093.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: bur:Bcep18194_B0420 Rieske (2Fe-2S) protein; Rieske (2Fe-2S) domain-containing protein 4473112 8328004 Amir_3812 Actinosynnema mirum DSM 43827 Rieske (2Fe-2S) domain-containing protein YP_003101537.1 4472135 D 446462 CDS YP_003101538.1 256377878 8328005 complement(4473221..4474792) 1 NC_013093.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: hypothetical protein; amine oxidase 4474792 8328005 Amir_3813 Actinosynnema mirum DSM 43827 amine oxidase YP_003101538.1 4473221 R 446462 CDS YP_003101539.1 256377879 8328006 complement(4474789..4475481) 1 NC_013093.1 PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: mno:Mnod_7055 ubiquinone/menaquinone biosynthesis methyltransferase; type 11 methyltransferase 4475481 8328006 Amir_3814 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003101539.1 4474789 R 446462 CDS YP_003101540.1 256377880 8328007 complement(4475471..4475797) 1 NC_013093.1 TIGRFAM: lycopene cyclase domain protein; lycopene cyclase domain-containing protein 4475797 8328007 Amir_3815 Actinosynnema mirum DSM 43827 lycopene cyclase domain-containing protein YP_003101540.1 4475471 R 446462 CDS YP_003101541.1 256377881 8328008 complement(4475794..4476141) 1 NC_013093.1 TIGRFAM: lycopene cyclase domain protein; KEGG: mxa:MXAN_0901 hypothetical protein; lycopene cyclase domain-containing protein 4476141 8328008 Amir_3816 Actinosynnema mirum DSM 43827 lycopene cyclase domain-containing protein YP_003101541.1 4475794 R 446462 CDS YP_003101542.1 256377882 8328009 4476417..4477088 1 NC_013093.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: sme:SMc01715 hypothetical protein; TetR family transcriptional regulator 4477088 8328009 Amir_3817 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101542.1 4476417 D 446462 CDS YP_003101543.1 256377883 8328010 4477085..4478221 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: gdj:Gdia_2837 monooxygenase FAD-binding; FAD-binding monooxygenase 4478221 8328010 Amir_3818 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101543.1 4477085 D 446462 CDS YP_003101544.1 256377884 8328011 complement(4478268..4479248) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: bur:Bcep18194_B1321 aldo/keto reductase; aldo/keto reductase 4479248 8328011 Amir_3819 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101544.1 4478268 R 446462 CDS YP_003101545.1 256377885 8328012 complement(4479361..4480224) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4480224 8328012 Amir_3820 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101545.1 4479361 R 446462 CDS YP_003101546.1 256377886 8328013 complement(4480366..4481229) 1 NC_013093.1 KEGG: calcium-binding protein; hypothetical protein 4481229 8328013 Amir_3821 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101546.1 4480366 R 446462 CDS YP_003101547.1 256377887 8328014 complement(4481725..4485456) 1 NC_013093.1 PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; Cna B domain-containing protein 4485456 8328014 Amir_3822 Actinosynnema mirum DSM 43827 Cna B domain-containing protein YP_003101547.1 4481725 R 446462 CDS YP_003101548.1 256377888 8328015 4485690..4486862 1 NC_013093.1 PFAM: protein of unknown function UPF0118; KEGG: mxa:MXAN_7270 hypothetical protein; hypothetical protein 4486862 8328015 Amir_3823 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101548.1 4485690 D 446462 CDS YP_003101549.1 256377889 8328016 complement(4486974..4488068) 1 NC_013093.1 hypothetical protein 4488068 8328016 Amir_3824 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101549.1 4486974 R 446462 CDS YP_003101550.1 256377890 8328017 complement(4488564..4488929) 1 NC_013093.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: bur:Bcep18194_B0126 5-carboxymethyl-2- hydroxymuconate isomerase; 5-carboxymethyl-2-hydroxymuconate isomerase 4488929 8328017 Amir_3825 Actinosynnema mirum DSM 43827 5-carboxymethyl-2-hydroxymuconate isomerase YP_003101550.1 4488564 R 446462 CDS YP_003101551.1 256377891 8328018 complement(4489057..4489482) 1 NC_013093.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: ajs:Ajs_3259 alkylhydroperoxidase; alkylhydroperoxidase like protein 4489482 8328018 Amir_3826 Actinosynnema mirum DSM 43827 alkylhydroperoxidase like protein YP_003101551.1 4489057 R 446462 CDS YP_003101552.1 256377892 8328019 complement(4489479..4490966) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: hch:HCH_02847 peptide arylation protein; AMP-dependent synthetase and ligase 4490966 8328019 Amir_3827 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101552.1 4489479 R 446462 CDS YP_003101553.1 256377893 8328020 complement(4490963..4492471) 1 NC_013093.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: nmu:Nmul_A0969 L-carnitine dehydratase/bile acid-inducible protein F; L-carnitine dehydratase/bile acid-inducible protein F 4492471 8328020 Amir_3828 Actinosynnema mirum DSM 43827 L-carnitine dehydratase/bile acid-inducible protein F YP_003101553.1 4490963 R 446462 CDS YP_003101554.1 256377894 8328021 complement(4492468..4493262) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: scl:sce8893 hypothetical protein; type 11 methyltransferase 4493262 8328021 Amir_3829 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003101554.1 4492468 R 446462 CDS YP_003101555.1 256377895 8328022 complement(4493303..4494838) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: pla:Plav_1766 cyclohexanecarboxylate-CoA ligase; AMP-dependent synthetase and ligase 4494838 8328022 Amir_3830 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101555.1 4493303 R 446462 CDS YP_003101556.1 256377896 8328023 complement(4494850..4496166) 1 NC_013093.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cvi:CV_1653 protoporphyrinogen oxidase; amine oxidase 4496166 8328023 Amir_3831 Actinosynnema mirum DSM 43827 amine oxidase YP_003101556.1 4494850 R 446462 CDS YP_003101557.1 256377897 8328024 complement(4496166..4497353) 1 NC_013093.1 PFAM: UbiA prenyltransferase; KEGG: hha:Hhal_1173 1,4-dihydroxy-2-naphthoate octaprenyltransferase; UbiA prenyltransferase 4497353 8328024 Amir_3832 Actinosynnema mirum DSM 43827 UbiA prenyltransferase YP_003101557.1 4496166 R 446462 CDS YP_003101558.1 256377898 8328025 complement(4497350..4497991) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: gur:Gura_3006 methyltransferase type 11; type 11 methyltransferase 4497991 8328025 Amir_3833 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003101558.1 4497350 R 446462 CDS YP_003101559.1 256377899 8328026 complement(4498001..4499137) 1 NC_013093.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 4499137 8328026 Amir_3834 Actinosynnema mirum DSM 43827 DegT/DnrJ/EryC1/StrS aminotransferase YP_003101559.1 4498001 R 446462 CDS YP_003101560.1 256377900 8328027 complement(4499134..4500354) 1 NC_013093.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce7344 NDP-sugar aminotransferase; glutamine--scyllo-inositol transaminase 4500354 8328027 Amir_3835 Actinosynnema mirum DSM 43827 glutamine--scyllo-inositol transaminase YP_003101560.1 4499134 R 446462 CDS YP_003101561.1 256377901 8328028 4500540..4501556 1 NC_013093.1 PFAM: oxidoreductase domain protein; KEGG: xac:XAC0681 oxidoreductase; oxidoreductase domain-containing protein 4501556 8328028 Amir_3836 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003101561.1 4500540 D 446462 CDS YP_003101562.1 256377902 8328029 4501546..4502418 1 NC_013093.1 PFAM: xylose isomerase; KEGG: sus:Acid_2233 xylose isomerase domain- containing protein; xylose isomerase 4502418 8328029 Amir_3837 Actinosynnema mirum DSM 43827 xylose isomerase YP_003101562.1 4501546 D 446462 CDS YP_003101563.1 256377903 8328030 4502415..4503653 1 NC_013093.1 PFAM: peptidase M20; KEGG: sus:Acid_2224 acetylornithine deacetylase; peptidase M20 4503653 8328030 Amir_3838 Actinosynnema mirum DSM 43827 peptidase M20 YP_003101563.1 4502415 D 446462 CDS YP_003101564.1 256377904 8328031 4503650..4504738 1 NC_013093.1 PFAM: malate/L-lactate dehydrogenase; KEGG: bpt:Bpet2680 malate dehydrogenase; malate/L-lactate dehydrogenase 4504738 8328031 Amir_3839 Actinosynnema mirum DSM 43827 malate/L-lactate dehydrogenase YP_003101564.1 4503650 D 446462 CDS YP_003101565.1 256377905 8328032 4504939..4505904 1 NC_013093.1 PFAM: oxidoreductase domain protein; KEGG: met:M446_2288 oxidoreductase domain- containing protein; oxidoreductase domain-containing protein 4505904 8328032 Amir_3840 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003101565.1 4504939 D 446462 CDS YP_003101566.1 256377906 8328033 4505904..4506392 1 NC_013093.1 hypothetical protein 4506392 8328033 Amir_3841 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101566.1 4505904 D 446462 CDS YP_003101567.1 256377907 8328034 complement(4506593..4507129) 1 NC_013093.1 PFAM: calcium-binding EF-hand-containing protein; SMART: calcium-binding EF-hand-containing protein; KEGG: bbt:BBta_5331 calcium-binding domain- containing protein; signal transduction protein with EFhand domain 4507129 8328034 Amir_3842 Actinosynnema mirum DSM 43827 signal transduction protein with EFhand domain YP_003101567.1 4506593 R 446462 CDS YP_003101568.1 256377908 8328035 complement(4507191..4508438) 1 NC_013093.1 TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sus:Acid_4597 UDP-glucose 6-dehydrogenase; nucleotide sugar dehydrogenase 4508438 8328035 Amir_3843 Actinosynnema mirum DSM 43827 nucleotide sugar dehydrogenase YP_003101568.1 4507191 R 446462 CDS YP_003101569.1 256377909 8328036 complement(4508479..4508793) 1 NC_013093.1 hypothetical protein 4508793 8328036 Amir_3844 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101569.1 4508479 R 446462 CDS YP_003101570.1 256377910 8328037 complement(4509194..4510117) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mlo:mlr3236 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 4510117 8328037 Amir_3845 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003101570.1 4509194 R 446462 CDS YP_003101571.1 256377911 8328038 4510239..4510859 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce6308 TetR family transcriptional regulator; TetR family transcriptional regulator 4510859 8328038 Amir_3846 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101571.1 4510239 D 446462 CDS YP_003101572.1 256377912 8328039 4510911..4511951 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: dsh:Dshi_2951 pyridoxal-5'-phosphate- dependent protein beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit 4511951 8328039 Amir_3847 Actinosynnema mirum DSM 43827 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003101572.1 4510911 D 446462 CDS YP_003101573.1 256377913 8328040 complement(4511982..4512608) 1 NC_013093.1 KEGG: mrd:Mrad2831_3526 PRC-barrel domain- containing protein; hypothetical protein 4512608 8328040 Amir_3848 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101573.1 4511982 R 446462 CDS YP_003101574.1 256377914 8328041 4512815..4516069 1 NC_013093.1 TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; KEGG: cps:CPS_2650 alpha-1,2-mannosidase family protein; alpha-1,2-mannosidase 4516069 8328041 Amir_3849 Actinosynnema mirum DSM 43827 alpha-1,2-mannosidase YP_003101574.1 4512815 D 446462 CDS YP_003101575.1 256377915 8328042 complement(4516133..4516372) 1 NC_013093.1 hypothetical protein 4516372 8328042 Amir_3850 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101575.1 4516133 R 446462 CDS YP_003101576.1 256377916 8328043 4516628..4517446 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: rle:RL1000 hydrolase; alpha/beta hydrolase fold protein 4517446 8328043 Amir_3851 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101576.1 4516628 D 446462 CDS YP_003101577.1 256377917 8328044 4517443..4518618 1 NC_013093.1 KEGG: rle:RL0999 two-component regulator sensor histidine kinase protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; PAS/PAC sensor protein 4518618 8328044 Amir_3852 Actinosynnema mirum DSM 43827 PAS/PAC sensor protein YP_003101577.1 4517443 D 446462 CDS YP_003101578.1 256377918 8328045 4518615..4518953 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; anti-sigma-factor antagonist 4518953 8328045 Amir_3853 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003101578.1 4518615 D 446462 CDS YP_003101579.1 256377919 8328046 4519202..4519720 1 NC_013093.1 KEGG: psb:Psyr_0893 hypothetical protein; hypothetical protein 4519720 8328046 Amir_3854 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101579.1 4519202 D 446462 CDS YP_003101580.1 256377920 8328047 4519852..4520397 1 NC_013093.1 KEGG: nha:Nham_0965 ChrB domain-containing protein; ChrB domain-containing protein 4520397 8328047 Amir_3855 Actinosynnema mirum DSM 43827 ChrB domain-containing protein YP_003101580.1 4519852 D 446462 CDS YP_003101581.1 256377921 8328048 4520406..4521563 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: afw:Anae109_0137 major facilitator transporter; major facilitator superfamily protein 4521563 8328048 Amir_3856 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101581.1 4520406 D 446462 CDS YP_003101582.1 256377922 8328049 4521705..4522241 1 NC_013093.1 TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: hne:HNE_1728 signal peptidase II; lipoprotein signal peptidase 4522241 8328049 Amir_3857 Actinosynnema mirum DSM 43827 lipoprotein signal peptidase YP_003101582.1 4521705 D 446462 CDS YP_003101583.1 256377923 8328050 complement(4522255..4522710) 1 NC_013093.1 KEGG: rle:RL3033 hypothetical protein; hypothetical protein 4522710 8328050 Amir_3858 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101583.1 4522255 R 446462 CDS YP_003101584.1 256377924 8328051 complement(4522751..4523536) 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: afw:Anae109_1735 SARP family transcriptional regulator; SARP family transcriptional regulator 4523536 8328051 Amir_3859 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003101584.1 4522751 R 446462 CDS YP_003101585.1 256377925 8328052 4523773..4523946 1 NC_013093.1 hypothetical protein 4523946 8328052 Amir_3860 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101585.1 4523773 D 446462 CDS YP_003101586.1 256377926 8328053 4524018..4526471 1 NC_013093.1 PFAM: Lantibiotic dehydratase domain protein; KEGG: scl:sce9070 hypothetical protein; Lantibiotic dehydratase domain-containing protein 4526471 8328053 Amir_3861 Actinosynnema mirum DSM 43827 Lantibiotic dehydratase domain-containing protein YP_003101586.1 4524018 D 446462 CDS YP_003101587.1 256377927 8328054 4526468..4527556 1 NC_013093.1 hypothetical protein 4527556 8328054 Amir_3862 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101587.1 4526468 D 446462 CDS YP_003101588.1 256377928 8328055 4527553..4529112 1 NC_013093.1 KEGG: afw:Anae109_2123 heat repeat-containing PBS lyase; hypothetical protein 4529112 8328055 Amir_3863 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101588.1 4527553 D 446462 CDS YP_003101589.1 256377929 8328056 4529109..4530809 1 NC_013093.1 PFAM: protein of unknown function DUF181; KEGG: bca:BCE_1377 hypothetical protein; hypothetical protein 4530809 8328056 Amir_3864 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101589.1 4529109 D 446462 CDS YP_003101590.1 256377930 8328057 4530818..4531948 1 NC_013093.1 hypothetical protein 4531948 8328057 Amir_3865 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101590.1 4530818 D 446462 CDS YP_003101591.1 256377931 8328058 4531948..4533504 1 NC_013093.1 KEGG: rsh:Rsph17029_3715 nitroreductase; hypothetical protein 4533504 8328058 Amir_3866 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101591.1 4531948 D 446462 CDS YP_003101592.1 256377932 8328059 complement(4533480..4534139) 1 NC_013093.1 KEGG: rme:Rmet_5057 transcriptional regulator, TetR family; TetR family transcriptional regulator 4534139 8328059 Amir_3867 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101592.1 4533480 R 446462 CDS YP_003101593.1 256377933 8328060 4534228..4535076 1 NC_013093.1 KEGG: swi:Swit_4207 esterase; esterase 4535076 8328060 Amir_3868 Actinosynnema mirum DSM 43827 esterase YP_003101593.1 4534228 D 446462 CDS YP_003101594.1 256377934 8328061 complement(4535465..4536478) 1 NC_013093.1 KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein 4536478 8328061 Amir_3869 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101594.1 4535465 R 446462 CDS YP_003101595.1 256377935 8328062 complement(4536619..4536849) 1 NC_013093.1 hypothetical protein 4536849 8328062 Amir_3870 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101595.1 4536619 R 446462 CDS YP_003101596.1 256377936 8328063 complement(4536951..4537634) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcb:BCB4264_A5589 DNA-binding response regulator YycF; winged helix family two component transcriptional regulator 4537634 8328063 Amir_3871 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003101596.1 4536951 R 446462 CDS YP_003101597.1 256377937 8328064 4537773..4538225 1 NC_013093.1 KEGG: met:M446_2237 hypothetical protein; hypothetical protein 4538225 8328064 Amir_3872 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101597.1 4537773 D 446462 CDS YP_003101598.1 256377938 8328066 complement(4538643..4539962) 1 NC_013093.1 PFAM: integrase family protein; KEGG: afw:Anae109_4219 phage integrase family protein; integrase family protein 4539962 8328066 Amir_3873 Actinosynnema mirum DSM 43827 integrase family protein YP_003101598.1 4538643 R 446462 CDS YP_003101599.1 256377939 8328068 complement(4540637..4542124) 1 NC_013093.1 KEGG: afw:Anae109_2123 heat repeat-containing PBS lyase; hypothetical protein 4542124 8328068 Amir_3875 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101599.1 4540637 R 446462 CDS YP_003101600.1 256377940 8328069 4542333..4542443 1 NC_013093.1 hypothetical protein 4542443 8328069 Amir_3876 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101600.1 4542333 D 446462 CDS YP_003101601.1 256377941 8328070 4542797..4543282 1 NC_013093.1 hypothetical protein 4543282 8328070 Amir_3877 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101601.1 4542797 D 446462 CDS YP_003101602.1 256377942 8328071 4543461..4547096 1 NC_013093.1 PFAM: protein of unknown function DUF312; KEGG: hso:HS_1058 large adhesin; hypothetical protein 4547096 8328071 Amir_3878 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101602.1 4543461 D 446462 CDS YP_003101603.1 256377943 8328072 complement(4547854..4548399) 1 NC_013093.1 hypothetical protein 4548399 8328072 Amir_3879 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101603.1 4547854 R 446462 CDS YP_003101604.1 256377944 8328073 complement(4548399..4552574) 1 NC_013093.1 PFAM: protein of unknown function DUF312; KEGG: hso:HS_1058 large adhesin; methyl-accepting chemotaxis sensory transducer 4552574 8328073 Amir_3880 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003101604.1 4548399 R 446462 CDS YP_003101605.1 256377945 8328075 4553487..4555022 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap 4555022 8328075 Amir_3882 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003101605.1 4553487 D 446462 CDS YP_003101606.1 256377946 8328076 4556416..4557636 1 NC_013093.1 PFAM: condensation domain protein; KEGG: bam:Bamb_1537 amino acid adenylation domain- containing protein; condensation domain-containing protein 4557636 8328076 Amir_3883 Actinosynnema mirum DSM 43827 condensation domain-containing protein YP_003101606.1 4556416 D 446462 CDS YP_003101607.1 256377947 8328078 4558282..4558644 1 NC_013093.1 KEGG: cak:Caul_1058 hypothetical protein; hypothetical protein 4558644 8328078 Amir_3885 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101607.1 4558282 D 446462 CDS YP_003101608.1 256377948 8328080 complement(4559023..4560003) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ank:AnaeK_2445 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4560003 8328080 Amir_3887 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101608.1 4559023 R 446462 CDS YP_003101609.1 256377949 8328081 4560100..4560663 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 4560663 8328081 Amir_3888 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101609.1 4560100 D 446462 CDS YP_003101610.1 256377950 8328083 4561320..4561814 1 NC_013093.1 PFAM: peptidoglycan-binding domain 1 protein; KEGG: hypothetical protein; peptidoglycan-binding domain 1 protein 4561814 8328083 Amir_3890 Actinosynnema mirum DSM 43827 peptidoglycan-binding domain 1 protein YP_003101610.1 4561320 D 446462 CDS YP_003101611.1 256377951 8328084 4562626..4566396 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: pen:PSEEN2717 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 4566396 8328084 Amir_3891 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101611.1 4562626 D 446462 CDS YP_003101612.1 256377952 8328085 4566393..4574876 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; condensation domain protein; KR domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pen:PSEEN2718 polyketide synthase (terminal component); amino acid adenylation domain-containing protein 4574876 8328085 Amir_3892 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101612.1 4566393 D 446462 CDS YP_003101613.1 256377953 8328086 4574899..4575771 1 NC_013093.1 PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: pen:PSEEN2720 dioxygenase, TauD; taurine dioxygenase 4575771 8328086 Amir_3893 Actinosynnema mirum DSM 43827 taurine dioxygenase YP_003101613.1 4574899 D 446462 CDS YP_003101614.1 256377954 8328087 4575773..4576984 1 NC_013093.1 PFAM: cytochrome P450; KEGG: scl:sce7167 hypothetical protein; cytochrome P450 4576984 8328087 Amir_3894 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101614.1 4575773 D 446462 CDS YP_003101615.1 256377955 8328088 4576981..4577658 1 NC_013093.1 KEGG: mes:Meso_2739 UDP-glucose pyrophosphorylase; hypothetical protein 4577658 8328088 Amir_3895 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101615.1 4576981 D 446462 CDS YP_003101616.1 256377956 8328089 4577661..4579112 1 NC_013093.1 PFAM: beta-lactamase; KEGG: xac:XAC0134 beta-lactamase; beta-lactamase 4579112 8328089 Amir_3896 Actinosynnema mirum DSM 43827 beta-lactamase YP_003101616.1 4577661 D 446462 CDS YP_003101617.1 256377957 8328090 4579109..4580302 1 NC_013093.1 PFAM: glycosyl transferase family 28; KEGG: scl:sce8970 glycosyl transferase; glycosyl transferase family protein 4580302 8328090 Amir_3897 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003101617.1 4579109 D 446462 CDS YP_003101618.1 256377958 8328091 4580448..4580888 1 NC_013093.1 hypothetical protein 4580888 8328091 Amir_3898 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101618.1 4580448 D 446462 CDS YP_003101619.1 256377959 8328092 complement(4580932..4581795) 1 NC_013093.1 PFAM: NmrA family protein; KEGG: scl:sce1557 hypothetical protein; NmrA family protein 4581795 8328092 Amir_3899 Actinosynnema mirum DSM 43827 NmrA family protein YP_003101619.1 4580932 R 446462 CDS YP_003101620.1 256377960 8328093 4581892..4582767 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bma:BMAA0201 transcriptional regulator CatR; LysR family transcriptional regulator 4582767 8328093 Amir_3900 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003101620.1 4581892 D 446462 CDS YP_003101621.1 256377961 8328094 complement(4582820..4583005) 1 NC_013093.1 hypothetical protein 4583005 8328094 Amir_3901 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101621.1 4582820 R 446462 CDS YP_003101622.1 256377962 8328095 complement(4583361..4583861) 1 NC_013093.1 PFAM: cupin; KEGG: hypothetical protein; cupin 4583861 8328095 Amir_3902 Actinosynnema mirum DSM 43827 cupin YP_003101622.1 4583361 R 446462 CDS YP_003101623.1 256377963 8328096 complement(4583907..4584851) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: rme:Rmet_4293 alcohol dehydrogenase, zinc- binding; alcohol dehydrogenase GroES domain-containing protein 4584851 8328096 Amir_3903 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003101623.1 4583907 R 446462 CDS YP_003101624.1 256377964 8328097 complement(4585012..4585866) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcj:BCAM0680 DNA-binding protein; XRE family transcriptional regulator 4585866 8328097 Amir_3904 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101624.1 4585012 R 446462 CDS YP_003101625.1 256377965 8328098 complement(4585944..4586396) 1 NC_013093.1 hypothetical protein 4586396 8328098 Amir_3905 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101625.1 4585944 R 446462 CDS YP_003101626.1 256377966 8328099 complement(4586393..4586659) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4586659 8328099 Amir_3906 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101626.1 4586393 R 446462 CDS YP_003101627.1 256377967 8328100 4587082..4587972 1 NC_013093.1 PFAM: glycoside hydrolase family 18; KEGG: hypothetical protein; mannosyl-glycoproteinendo-beta-N-acetylglucosami nidase 4587972 8328100 Amir_3907 Actinosynnema mirum DSM 43827 mannosyl-glycoproteinendo-beta-N-acetylglucosami nidase YP_003101627.1 4587082 D 446462 CDS YP_003101628.1 256377968 8328104 4590595..4591464 1 NC_013093.1 PFAM: transport system permease protein; KEGG: pmy:Pmen_4564 transport system permease protein; transport system permease 4591464 8328104 Amir_3911 Actinosynnema mirum DSM 43827 transport system permease YP_003101628.1 4590595 D 446462 CDS YP_003101629.1 256377969 8328105 4591490..4592509 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: pen:PSEEN3067 Fe uptake ABC transporter, periplasmic binding protein; periplasmic binding protein 4592509 8328105 Amir_3912 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003101629.1 4591490 D 446462 CDS YP_003101630.1 256377970 8328106 complement(4592616..4593392) 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: pau:PA14_39660 hypothetical protein; type 12 methyltransferase 4593392 8328106 Amir_3913 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003101630.1 4592616 R 446462 CDS YP_003101631.1 256377971 8328107 complement(4593389..4594213) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pmy:Pmen_4566 ABC transporter; ABC transporter 4594213 8328107 Amir_3914 Actinosynnema mirum DSM 43827 ABC transporter YP_003101631.1 4593389 R 446462 CDS YP_003101632.1 256377972 8328108 complement(4594210..4595292) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: dac:Daci_3791 transport system permease protein; transport system permease 4595292 8328108 Amir_3915 Actinosynnema mirum DSM 43827 transport system permease YP_003101632.1 4594210 R 446462 CDS YP_003101633.1 256377973 8328109 complement(4595289..4596419) 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: bpm:BURPS1710b_3208 periplasmic binding protein; periplasmic binding protein 4596419 8328109 Amir_3916 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003101633.1 4595289 R 446462 CDS YP_003101634.1 256377974 8328110 complement(4596416..4597690) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: dsh:Dshi_2354 major facilitator transporter; major facilitator superfamily protein 4597690 8328110 Amir_3917 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101634.1 4596416 R 446462 CDS YP_003101635.1 256377975 8328111 complement(4597687..4598985) 1 NC_013093.1 KEGG: bha:BH2073 hypothetical protein; hypothetical protein 4598985 8328111 Amir_3918 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101635.1 4597687 R 446462 CDS YP_003101636.1 256377976 8328112 complement(4599030..4599821) 1 NC_013093.1 KEGG: bha:BH2072 hypothetical protein; hypothetical protein 4599821 8328112 Amir_3919 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101636.1 4599030 R 446462 CDS YP_003101637.1 256377977 8328113 complement(4599882..4600694) 1 NC_013093.1 KEGG: bha:BH2071 hypothetical protein; hypothetical protein 4600694 8328113 Amir_3920 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101637.1 4599882 R 446462 CDS YP_003101638.1 256377978 8328114 complement(4600924..4601322) 1 NC_013093.1 hypothetical protein 4601322 8328114 Amir_3921 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101638.1 4600924 R 446462 CDS YP_003101639.1 256377979 8328115 4601669..4602676 1 NC_013093.1 KEGG: rso:RS03054 hypothetical protein; hypothetical protein 4602676 8328115 Amir_3922 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101639.1 4601669 D 446462 CDS YP_003101640.1 256377980 8328116 4602815..4604995 1 NC_013093.1 KEGG: bpy:Bphyt_0257 hypothetical protein; hypothetical protein 4604995 8328116 Amir_3923 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101640.1 4602815 D 446462 CDS YP_003101641.1 256377981 8328117 4605007..4606827 1 NC_013093.1 PFAM: carbamoyltransferase; KEGG: bpy:Bphyt_0258 carbamoyltransferase; carbamoyltransferase 4606827 8328117 Amir_3924 Actinosynnema mirum DSM 43827 carbamoyltransferase YP_003101641.1 4605007 D 446462 CDS YP_003101642.1 256377982 8328119 complement(4606993..4608054) 1 NC_013093.1 PFAM: glycoside hydrolase family 43; KEGG: cja:CJA_0819 alpha-L-arabinfuranosidase, , abf43M; alpha-N-arabinofuranosidase 4608054 8328119 Amir_3926 Actinosynnema mirum DSM 43827 alpha-N-arabinofuranosidase YP_003101642.1 4606993 R 446462 CDS YP_003101643.1 256377983 8328120 complement(4608144..4609454) 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: sde:Sde_3710 arabinogalactan endo-1,4-beta- galactosidase; Ricin B lectin 4609454 8328120 Amir_3927 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101643.1 4608144 R 446462 CDS YP_003101644.1 256377984 8328122 4610870..4612102 1 NC_013093.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: mfa:Mfla_0439 aminomethyltransferase; glycine cleavage T protein (aminomethyl transferase) 4612102 8328122 Amir_3929 Actinosynnema mirum DSM 43827 glycine cleavage T protein (aminomethyl transferase) YP_003101644.1 4610870 D 446462 CDS YP_003101645.1 256377985 8328123 4612099..4613166 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: sus:Acid_5898 N-methyltryptophan oxidase; FAD dependent oxidoreductase 4613166 8328123 Amir_3930 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003101645.1 4612099 D 446462 CDS YP_003101646.1 256377986 8328124 4613163..4614155 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: gur:Gura_3526 aldo/keto reductase; aldo/keto reductase 4614155 8328124 Amir_3931 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101646.1 4613163 D 446462 CDS YP_003101647.1 256377987 8328125 4614163..4614450 1 NC_013093.1 hypothetical protein 4614450 8328125 Amir_3932 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101647.1 4614163 D 446462 CDS YP_003101648.1 256377988 8328126 4614478..4616217 1 NC_013093.1 PFAM: carbamoyltransferase; KEGG: nha:Nham_2127 carbamoyltransferase; carbamoyltransferase 4616217 8328126 Amir_3933 Actinosynnema mirum DSM 43827 carbamoyltransferase YP_003101648.1 4614478 D 446462 CDS YP_003101649.1 256377989 8328127 4616214..4616993 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: tbd:Tbd_2162 hypothetical protein; type 11 methyltransferase 4616993 8328127 Amir_3934 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003101649.1 4616214 D 446462 CDS YP_003101650.1 256377990 8328128 4616995..4618212 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: ppu:PP_3961 major facilitator transporter; major facilitator superfamily protein 4618212 8328128 Amir_3935 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101650.1 4616995 D 446462 CDS YP_003101651.1 256377991 8328131 4619639..4620379 1 NC_013093.1 hypothetical protein 4620379 8328131 Amir_3938 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101651.1 4619639 D 446462 CDS YP_003101652.1 256377992 8328132 complement(4620663..4621283) 1 NC_013093.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: cvi:CV_3295 hypothetical protein; bifunctional deaminase-reductase domain-containing protein 4621283 8328132 Amir_3939 Actinosynnema mirum DSM 43827 bifunctional deaminase-reductase domain-containing protein YP_003101652.1 4620663 R 446462 CDS YP_003101653.1 256377993 8328133 complement(4621283..4621861) 1 NC_013093.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: afw:Anae109_0511 activator of HSP90 ATPase 1 family protein; Activator of Hsp90 ATPase 1 family protein 4621861 8328133 Amir_3940 Actinosynnema mirum DSM 43827 Activator of Hsp90 ATPase 1 family protein YP_003101653.1 4621283 R 446462 CDS YP_003101654.1 256377994 8328134 complement(4621865..4622206) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: afw:Anae109_0512 regulatory protein ArsR; ArsR family transcriptional regulator 4622206 8328134 Amir_3941 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003101654.1 4621865 R 446462 CDS YP_003101655.1 256377995 8328135 complement(4622296..4622889) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ent:Ent638_3529 XRE family transcriptional regulator; XRE family transcriptional regulator 4622889 8328135 Amir_3942 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101655.1 4622296 R 446462 CDS YP_003101656.1 256377996 8328136 4622991..4624229 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: smd:Smed_5551 hypothetical protein; major facilitator superfamily protein 4624229 8328136 Amir_3943 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101656.1 4622991 D 446462 CDS YP_003101657.1 256377997 8328137 complement(4624226..4625626) 1 NC_013093.1 KEGG: sde:Sde_0791 alpha-L-arabinofuranosidase; PFAM: glycoside hydrolase family 43; Ricin B lectin; SMART: Ricin B lectin; alpha-N-arabinofuranosidase 4625626 8328137 Amir_3944 Actinosynnema mirum DSM 43827 alpha-N-arabinofuranosidase YP_003101657.1 4624226 R 446462 CDS YP_003101658.1 256377998 8328138 4625812..4626699 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: mes:Meso_3900 aldo/keto reductase; aldo/keto reductase 4626699 8328138 Amir_3945 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101658.1 4625812 D 446462 CDS YP_003101659.1 256377999 8328139 4626914..4627252 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sus:Acid_5261 anti-sigma-factor antagonist; anti-sigma-factor antagonist 4627252 8328139 Amir_3946 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003101659.1 4626914 D 446462 CDS YP_003101660.1 256378000 8328140 complement(4627327..4628079) 1 NC_013093.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: acp:A2cp1_0906 transcriptional regulator, LuxR family; LuxR family transcriptional regulator 4628079 8328140 Amir_3947 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101660.1 4627327 R 446462 CDS YP_003101661.1 256378001 8328141 complement(4628751..4630325) 1 NC_013093.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bph:Bphy_3357 EmrB/QacA family drug resistance transporter; EmrB/QacA subfamily drug resistance transporter 4630325 8328141 Amir_3948 Actinosynnema mirum DSM 43827 EmrB/QacA subfamily drug resistance transporter YP_003101661.1 4628751 R 446462 CDS YP_003101662.1 256378002 8328142 complement(4630322..4630954) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: transcriptional regulator protein; TetR family transcriptional regulator 4630954 8328142 Amir_3949 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101662.1 4630322 R 446462 CDS YP_003101663.1 256378003 8328143 complement(4631056..4631766) 1 NC_013093.1 KEGG: acp:A2cp1_0909 translation initiation factor SUI1; hypothetical protein 4631766 8328143 Amir_3950 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101663.1 4631056 R 446462 CDS YP_003101664.1 256378004 8328144 complement(4631763..4632101) 1 NC_013093.1 hypothetical protein 4632101 8328144 Amir_3951 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101664.1 4631763 R 446462 CDS YP_003101665.1 256378005 8328145 complement(4632114..4633286) 1 NC_013093.1 KEGG: YALI0E33891p; hypothetical protein 4633286 8328145 Amir_3952 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101665.1 4632114 R 446462 CDS YP_003101666.1 256378006 8328146 complement(4633430..4633744) 1 NC_013093.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: azc:AZC_4213 anti-sigma factor antagonist; anti-sigma-factor antagonist 4633744 8328146 Amir_3953 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003101666.1 4633430 R 446462 CDS YP_003101667.1 256378007 8328147 complement(4633741..4637853) 1 NC_013093.1 KEGG: cti:RALTA_B0128 multi-site sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein; multi-sensor signal transduction histidine kinase 4637853 8328147 Amir_3954 Actinosynnema mirum DSM 43827 multi-sensor signal transduction histidine kinase YP_003101667.1 4633741 R 446462 CDS YP_003101668.1 256378008 8328148 complement(4637943..4638350) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; ATP-binding region ATPase domain-containing protein 4638350 8328148 Amir_3955 Actinosynnema mirum DSM 43827 ATP-binding region ATPase domain-containing protein YP_003101668.1 4637943 R 446462 CDS YP_003101669.1 256378009 8328149 4638618..4639436 1 NC_013093.1 KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein 4639436 8328149 Amir_3956 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101669.1 4638618 D 446462 CDS YP_003101670.1 256378010 8328150 4639751..4640620 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; cyclic nucleotide- binding; KEGG: swi:Swit_2706 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 4640620 8328150 Amir_3957 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003101670.1 4639751 D 446462 CDS YP_003101671.1 256378011 8328151 complement(4640945..4642042) 1 NC_013093.1 PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; KEGG: sde:Sde_0943 ribosomal protein S5; pectate lyase/Amb allergen 4642042 8328151 Amir_3958 Actinosynnema mirum DSM 43827 pectate lyase/Amb allergen YP_003101671.1 4640945 R 446462 CDS YP_003101672.1 256378012 8328152 complement(4642382..4643653) 1 NC_013093.1 KEGG: acetyl xylan esterase; K01567; TIGRFAM: esterase, PHB depolymerase family; PFAM: cellulose-binding family II; SMART: cellulose-binding family II; esterase, PHB depolymerase family 4643653 8328152 Amir_3959 Actinosynnema mirum DSM 43827 esterase, PHB depolymerase family YP_003101672.1 4642382 R 446462 CDS YP_003101673.1 256378013 8328153 complement(4643730..4644617) 1 NC_013093.1 KEGG: vvu:VV2_0700 beta-lactamase class A; hypothetical protein 4644617 8328153 Amir_3960 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101673.1 4643730 R 446462 CDS YP_003101674.1 256378014 8328154 complement(4644629..4645495) 1 NC_013093.1 PFAM: regulatory protein LysR; KEGG: bmj:BMULJ_04428 LysR family transcriptional regulator; LysR family transcriptional regulator 4645495 8328154 Amir_3961 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003101674.1 4644629 R 446462 CDS YP_003101675.1 256378015 8328155 4645608..4646555 1 NC_013093.1 PFAM: beta-lactamase; penicillin-binding protein transpeptidase; KEGG: bsu:BSU18800 beta-lactamase precursor; beta-lactamase 4646555 8328155 Amir_3962 Actinosynnema mirum DSM 43827 beta-lactamase YP_003101675.1 4645608 D 446462 CDS YP_003101676.1 256378016 8328156 complement(4646925..4647869) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sml:Smlt2229 hypothetical protein; XRE family transcriptional regulator 4647869 8328156 Amir_3963 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101676.1 4646925 R 446462 CDS YP_003101677.1 256378017 8328157 4648428..4649474 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: sme:SMc00680 zinc-type alcohol dehydrogenase protein; alcohol dehydrogenase GroES domain-containing protein 4649474 8328157 Amir_3964 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003101677.1 4648428 D 446462 CDS YP_003101678.1 256378018 8328159 4649883..4650263 1 NC_013093.1 hypothetical protein 4650263 8328159 Amir_3966 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101678.1 4649883 D 446462 CDS YP_003101679.1 256378019 8328160 complement(4650450..4650869) 1 NC_013093.1 KEGG: dac:Daci_4779 SPW repeat-containing protein; hypothetical protein 4650869 8328160 Amir_3967 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101679.1 4650450 R 446462 CDS YP_003101680.1 256378020 8328161 4651137..4652510 1 NC_013093.1 KEGG: scl:sce6003 protein kinase; hypothetical protein 4652510 8328161 Amir_3968 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101680.1 4651137 D 446462 CDS YP_003101681.1 256378021 8328162 complement(4652552..4652980) 1 NC_013093.1 hypothetical protein 4652980 8328162 Amir_3969 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101681.1 4652552 R 446462 CDS YP_003101682.1 256378022 8328164 complement(4653718..4655205) 1 NC_013093.1 PFAM: pyrrolo-quinoline quinone; SMART: pyrrolo-quinoline quinone; KEGG: rso:RSc1218 lipoprotein transmembrane; pyrrolo-quinoline quinone 4655205 8328164 Amir_3971 Actinosynnema mirum DSM 43827 pyrrolo-quinoline quinone YP_003101682.1 4653718 R 446462 CDS YP_003101683.1 256378023 8328165 4655564..4656814 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: pde:Pden_1503 hypothetical protein; FAD-binding monooxygenase 4656814 8328165 Amir_3972 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101683.1 4655564 D 446462 CDS YP_003101684.1 256378024 8328166 complement(4656811..4658328) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: ABC-type dipeptide transport system, periplasmic component; K02035 peptide/nickel transport system substrate-binding protein; family 5 extracellular solute-binding protein 4658328 8328166 Amir_3973 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003101684.1 4656811 R 446462 CDS YP_003101685.1 256378025 8328167 complement(4658604..4659263) 1 NC_013093.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4659263 8328167 Amir_3974 Actinosynnema mirum DSM 43827 LexA repressor YP_003101685.1 4658604 R 446462 CDS YP_003101686.1 256378026 8328168 4659383..4659994 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bja:bll7174 transcriptional regulatory protein; TetR family transcriptional regulator 4659994 8328168 Amir_3975 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101686.1 4659383 D 446462 CDS YP_003101687.1 256378027 8328169 4660107..4660841 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bpy:Bphyt_1098 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4660841 8328169 Amir_3976 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101687.1 4660107 D 446462 CDS YP_003101688.1 256378028 8328170 4660957..4661259 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4661259 8328170 Amir_3977 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101688.1 4660957 D 446462 CDS YP_003101689.1 256378029 8328171 complement(4661377..4662579) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: mxa:MXAN_2233 major facilitator family transporter; major facilitator superfamily protein 4662579 8328171 Amir_3978 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101689.1 4661377 R 446462 CDS YP_003101690.1 256378030 8328172 4662650..4663261 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mrd:Mrad2831_1768 TetR family transcriptional regulator; TetR family transcriptional regulator 4663261 8328172 Amir_3979 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101690.1 4662650 D 446462 CDS YP_003101691.1 256378031 8328173 4663413..4664120 1 NC_013093.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 4664120 ribA 8328173 ribA Actinosynnema mirum DSM 43827 GTP cyclohydrolase II YP_003101691.1 4663413 D 446462 CDS YP_003101692.1 256378032 8328174 4664117..4664719 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: oan:Oant_4026 transcriptional regulator, MarR family; MarR family transcriptional regulator 4664719 8328174 Amir_3981 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003101692.1 4664117 D 446462 CDS YP_003101693.1 256378033 8328175 4664740..4665765 1 NC_013093.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; KEGG: xca:xccb100_3664 riboflavin biosynthesis protein RibD (diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-[5-phosphoribosylamino]uracil reductase); riboflavin biosynthesis protein RibD 4665765 8328175 Amir_3982 Actinosynnema mirum DSM 43827 riboflavin biosynthesis protein RibD YP_003101693.1 4664740 D 446462 CDS YP_003101694.1 256378034 8328176 4665992..4667137 1 NC_013093.1 PFAM: peptidase dimerization domain protein; peptidase M20; KEGG: aba:Acid345_0237 peptidase M20; peptidase dimerization domain-containing protein 4667137 8328176 Amir_3983 Actinosynnema mirum DSM 43827 peptidase dimerization domain-containing protein YP_003101694.1 4665992 D 446462 CDS YP_003101695.1 256378035 8328177 4667269..4669086 1 NC_013093.1 PFAM: PBS lyase HEAT domain protein repeat- containing protein; HEAT domain containing protein; SMART: PBS lyase HEAT domain protein repeat- containing protein; KEGG: afw:Anae109_2123 heat repeat-containing PBS lyase; PBS lyase HEAT domain-containing protein repeat-containing protein 4669086 8328177 Amir_3984 Actinosynnema mirum DSM 43827 PBS lyase HEAT domain-containing protein repeat-containing protein YP_003101695.1 4667269 D 446462 CDS YP_003101696.1 256378036 8328178 4669083..4669709 1 NC_013093.1 KEGG: hypothetical protein LOC100014234; hypothetical protein 4669709 8328178 Amir_3985 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101696.1 4669083 D 446462 CDS YP_003101697.1 256378037 8328179 complement(4669702..4670595) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xcv:XCV1204 oxidoreductase; short-chain dehydrogenase/reductase SDR 4670595 8328179 Amir_3986 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101697.1 4669702 R 446462 CDS YP_003101698.1 256378038 8328180 complement(4670740..4671501) 1 NC_013093.1 PFAM: glycoside hydrolase family 12; KEGG: hypothetical protein; glycoside hydrolase family protein 4671501 8328180 Amir_3987 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101698.1 4670740 R 446462 CDS YP_003101699.1 256378039 8328181 complement(4671675..4672532) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: psb:Psyr_0904 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4672532 8328181 Amir_3988 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101699.1 4671675 R 446462 CDS YP_003101700.1 256378040 8328182 4672872..4673924 1 NC_013093.1 KEGG: tgr:Tgr7_0702 glutathione S- transferase; glutathione S-transferase 4673924 8328182 Amir_3989 Actinosynnema mirum DSM 43827 glutathione S-transferase YP_003101700.1 4672872 D 446462 CDS YP_003101701.1 256378041 8328183 4673944..4674690 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: atc:AGR_pAT_269 hypothetical protein; MerR family transcriptional regulator 4674690 8328183 Amir_3990 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003101701.1 4673944 D 446462 CDS YP_003101702.1 256378042 8328185 4676336..4677082 1 NC_013093.1 PFAM: NmrA family protein; dTDP-4-dehydrorhamnose reductase; KEGG: bpa:BPP3249 hypothetical protein; NmrA family protein 4677082 8328185 Amir_3992 Actinosynnema mirum DSM 43827 NmrA family protein YP_003101702.1 4676336 D 446462 CDS YP_003101703.1 256378043 8328186 complement(4677058..4677591) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: mlo:mll8365 hypothetical protein; hypothetical protein 4677591 8328186 Amir_3993 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101703.1 4677058 R 446462 CDS YP_003101704.1 256378044 8328187 4677708..4679381 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein 4679381 8328187 Amir_3994 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003101704.1 4677708 D 446462 CDS YP_003101705.1 256378045 8328188 complement(4679427..4679972) 1 NC_013093.1 KEGG: rpb:RPB_1369 hypothetical protein; hypothetical protein 4679972 8328188 Amir_3995 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101705.1 4679427 R 446462 CDS YP_003101706.1 256378046 8328189 complement(4679977..4680414) 1 NC_013093.1 KEGG: ank:AnaeK_1205 protein of unknown function DUF1028; hypothetical protein 4680414 8328189 Amir_3996 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101706.1 4679977 R 446462 CDS YP_003101707.1 256378047 8328190 4680580..4681461 1 NC_013093.1 PFAM: SEFIR domain protein; KEGG: gme:Gmet_1793 hypothetical protein; SEFIR domain-containing protein 4681461 8328190 Amir_3997 Actinosynnema mirum DSM 43827 SEFIR domain-containing protein YP_003101707.1 4680580 D 446462 CDS YP_003101708.1 256378048 8328191 4681533..4681718 1 NC_013093.1 hypothetical protein 4681718 8328191 Amir_3998 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101708.1 4681533 D 446462 CDS YP_003101709.1 256378049 8328192 4681806..4682201 1 NC_013093.1 KEGG: nwi:Nwi_1916 hypothetical protein; hypothetical protein 4682201 8328192 Amir_3999 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101709.1 4681806 D 446462 CDS YP_003101710.1 256378050 8328193 4682227..4683372 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 4683372 8328193 Amir_4000 Actinosynnema mirum DSM 43827 histidine kinase YP_003101710.1 4682227 D 446462 CDS YP_003101711.1 256378051 8328194 4683398..4684051 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 4684051 8328194 Amir_4001 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101711.1 4683398 D 446462 CDS YP_003101712.1 256378052 8328195 4684166..4684633 1 NC_013093.1 hypothetical protein 4684633 8328195 Amir_4002 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101712.1 4684166 D 446462 CDS YP_003101713.1 256378053 8328196 4684882..4685634 1 NC_013093.1 PFAM: Thioesterase; KEGG: pau:PA14_09230 pyochelin biosynthetic protein PchC; oleoyl-(acyl-carrier-protein) hydrolase 4685634 8328196 Amir_4003 Actinosynnema mirum DSM 43827 oleoyl-(acyl-carrier-protein) hydrolase YP_003101713.1 4684882 D 446462 CDS YP_003101714.1 256378054 8328197 complement(4685708..4686625) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4686625 8328197 Amir_4004 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101714.1 4685708 R 446462 CDS YP_003101715.1 256378055 8328198 4686747..4687937 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: msl:Msil_0387 monooxygenase FAD-binding; FAD-binding monooxygenase 4687937 8328198 Amir_4005 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101715.1 4686747 D 446462 CDS YP_003101716.1 256378056 8328199 complement(4687988..4688569) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: acp:A2cp1_2482 transcriptional regulator, TetR family; TetR family transcriptional regulator 4688569 8328199 Amir_4006 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101716.1 4687988 R 446462 CDS YP_003101717.1 256378057 8328200 complement(4688647..4689456) 1 NC_013093.1 PFAM: xylose isomerase; KEGG: smd:Smed_3334 xylose isomerase domain protein TIM barrel; xylose isomerase 4689456 8328200 Amir_4007 Actinosynnema mirum DSM 43827 xylose isomerase YP_003101717.1 4688647 R 446462 CDS YP_003101718.1 256378058 8328201 complement(4689453..4690595) 1 NC_013093.1 KEGG: sme:SMc04132 hypothetical protein; hypothetical protein 4690595 8328201 Amir_4008 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101718.1 4689453 R 446462 CDS YP_003101719.1 256378059 8328202 complement(4690592..4691737) 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: atc:AGR_L_3386 hypothetical protein; oxidoreductase domain-containing protein 4691737 8328202 Amir_4009 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003101719.1 4690592 R 446462 CDS YP_003101720.1 256378060 8328204 complement(4693102..4693743) 1 NC_013093.1 PFAM: superoxide dismutase copper/zinc binding; superoxide dismutase copper/zinc binding 4693743 8328204 Amir_4011 Actinosynnema mirum DSM 43827 superoxide dismutase copper/zinc binding YP_003101720.1 4693102 R 446462 CDS YP_003101721.1 256378061 8328205 4693917..4695188 1 NC_013093.1 KEGG: rlt:Rleg2_2895 heat domain containing protein; heat domain containing protein 4695188 8328205 Amir_4012 Actinosynnema mirum DSM 43827 heat domain containing protein YP_003101721.1 4693917 D 446462 CDS YP_003101722.1 256378062 8328206 4695762..4696562 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: pde:Pden_1042 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4696562 8328206 Amir_4013 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101722.1 4695762 D 446462 CDS YP_003101723.1 256378063 8328207 complement(4696610..4697110) 1 NC_013093.1 PFAM: transcriptional regulator domain protein; KEGG: bcb:BCB4264_A1351 DNA-binding response regulator; winged helix family two component transcriptional regulator 4697110 8328207 Amir_4014 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003101723.1 4696610 R 446462 CDS YP_003101724.1 256378064 8328208 4697316..4698173 1 NC_013093.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: sde:Sde_1920 methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NADP(+)) 4698173 8328208 Amir_4015 Actinosynnema mirum DSM 43827 methylenetetrahydrofolate dehydrogenase (NADP(+)) YP_003101724.1 4697316 D 446462 CDS YP_003101725.1 256378065 8328209 complement(4698370..4699722) 1 NC_013093.1 KEGG: sus:Acid_5487 O-acetylhomoserine/O- acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; O-acetylhomoserine/O-acetylserine sulfhydrylase 4699722 8328209 Amir_4016 Actinosynnema mirum DSM 43827 O-acetylhomoserine/O-acetylserine sulfhydrylase YP_003101725.1 4698370 R 446462 CDS YP_003101726.1 256378066 8328210 complement(4699865..4700668) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bbt:BBta_7223 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4700668 8328210 Amir_4017 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101726.1 4699865 R 446462 CDS YP_003101727.1 256378067 8328211 complement(4701286..4701927) 1 NC_013093.1 KEGG: jan:Jann_0393 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4701927 8328211 Amir_4018 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003101727.1 4701286 R 446462 CDS YP_003101728.1 256378068 8328212 4702898..4719478 1 NC_013093.1 PFAM: acyl transferase; beta-ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I; acyl transferase 4719478 8328212 Amir_4019 Actinosynnema mirum DSM 43827 acyl transferase YP_003101728.1 4702898 D 446462 CDS YP_003101729.1 256378069 8328213 complement(4719491..4720342) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: oca:OCAR_4999 hypothetical protein; luciferase-like monooxygenase 4720342 8328213 Amir_4020 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003101729.1 4719491 R 446462 CDS YP_003101730.1 256378070 8328214 complement(4720433..4721644) 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: dde:Dde_2559 beta-N-acetylhexosaminidase; glycoside hydrolase family protein 4721644 8328214 Amir_4021 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101730.1 4720433 R 446462 CDS YP_003101731.1 256378071 8328215 4722188..4724440 1 NC_013093.1 KEGG: acp:A2cp1_0462 exonuclease SbcC; hypothetical protein 4724440 8328215 Amir_4022 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101731.1 4722188 D 446462 CDS YP_003101732.1 256378072 8328216 4724509..4725687 1 NC_013093.1 hypothetical protein 4725687 8328216 Amir_4023 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101732.1 4724509 D 446462 CDS YP_003101733.1 256378073 8328217 4725938..4726183 1 NC_013093.1 hypothetical protein 4726183 8328217 Amir_4024 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101733.1 4725938 D 446462 CDS YP_003101734.1 256378074 8328218 4726180..4726443 1 NC_013093.1 hypothetical protein 4726443 8328218 Amir_4025 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101734.1 4726180 D 446462 CDS YP_003101735.1 256378075 8328219 complement(4726467..4726778) 1 NC_013093.1 hypothetical protein 4726778 8328219 Amir_4026 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101735.1 4726467 R 446462 CDS YP_003101736.1 256378076 8328220 4726953..4727339 1 NC_013093.1 hypothetical protein 4727339 8328220 Amir_4027 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101736.1 4726953 D 446462 CDS YP_003101737.1 256378077 8328221 complement(4727392..4728873) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: sus:Acid_7020 WD-40 repeat-containing serine/threonin protein kinase; serine/threonine protein kinase 4728873 8328221 Amir_4028 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003101737.1 4727392 R 446462 CDS YP_003101738.1 256378078 8328222 complement(4729017..4731491) 1 NC_013093.1 KEGG: rle:pRL90161 hypothetical protein; hypothetical protein 4731491 8328222 Amir_4029 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101738.1 4729017 R 446462 CDS YP_003101739.1 256378079 8328223 4731947..4732843 1 NC_013093.1 KEGG: bba:Bd3647 hypothetical protein; hypothetical protein 4732843 8328223 Amir_4030 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101739.1 4731947 D 446462 CDS YP_003101740.1 256378080 8328224 complement(4733014..4734609) 1 NC_013093.1 KEGG: hypothetical protein; PFAM: Ricin B lectin; SMART: Ricin B lectin; glucan endo-1,3-beta-D-glucosidase 4734609 8328224 Amir_4031 Actinosynnema mirum DSM 43827 glucan endo-1,3-beta-D-glucosidase YP_003101740.1 4733014 R 446462 CDS YP_003101741.1 256378081 8328225 complement(4734902..4736407) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: vei:Veis_4674 acyl-CoA synthetase; AMP-dependent synthetase and ligase 4736407 8328225 Amir_4032 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101741.1 4734902 R 446462 CDS YP_003101742.1 256378082 8328226 4736646..4738229 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: RCJMB04_10a6, FOXRED2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4738229 8328226 Amir_4033 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003101742.1 4736646 D 446462 CDS YP_003101743.1 256378083 8328227 4738226..4739347 1 NC_013093.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: scl:sce7671 (S)-2-hydroxy-acid oxidase; FMN-dependent alpha-hydroxy acid dehydrogenase 4739347 8328227 Amir_4034 Actinosynnema mirum DSM 43827 FMN-dependent alpha-hydroxy acid dehydrogenase YP_003101743.1 4738226 D 446462 CDS YP_003101744.1 256378084 8328228 4739344..4740780 1 NC_013093.1 KEGG: predicted protein; cytochrome P450-like protein 4740780 8328228 Amir_4035 Actinosynnema mirum DSM 43827 cytochrome P450-like protein YP_003101744.1 4739344 D 446462 CDS YP_003101745.1 256378085 8328229 4741043..4742311 1 NC_013093.1 PFAM: sodium/hydrogen exchanger; KEGG: pzu:PHZ_c2901 Kef-type K+ transport system, membrane component; sodium/hydrogen exchanger 4742311 8328229 Amir_4036 Actinosynnema mirum DSM 43827 sodium/hydrogen exchanger YP_003101745.1 4741043 D 446462 CDS YP_003101746.1 256378086 8328231 4742888..4744243 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: histidine kinase; histidine kinase 4744243 8328231 Amir_4038 Actinosynnema mirum DSM 43827 histidine kinase YP_003101746.1 4742888 D 446462 CDS YP_003101747.1 256378087 8328232 4744828..4745112 1 NC_013093.1 KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein 4745112 8328232 Amir_4039 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101747.1 4744828 D 446462 CDS YP_003101748.1 256378088 8328233 complement(4745429..4745929) 1 NC_013093.1 KEGG: asa:ASA_3456 hypothetical protein; hypothetical protein 4745929 8328233 Amir_4040 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101748.1 4745429 R 446462 CDS YP_003101749.1 256378089 8328234 complement(4746067..4751058) 1 NC_013093.1 KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein 4751058 8328234 Amir_4041 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101749.1 4746067 R 446462 CDS YP_003101750.1 256378090 8328235 complement(4751173..4752312) 1 NC_013093.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: reu:Reut_B4643 mandelate racemase/muconate lactonizing protein; mandelate racemase/muconate lactonizing protein 4752312 8328235 Amir_4042 Actinosynnema mirum DSM 43827 mandelate racemase/muconate lactonizing protein YP_003101750.1 4751173 R 446462 CDS YP_003101751.1 256378091 8328237 4753130..4755073 1 NC_013093.1 PFAM: Na-Ca exchanger/integrin-beta4; SMART: Na-Ca exchanger/integrin-beta4; KEGG: hch:HCH_05909 hypothetical protein; Na-Ca exchanger/integrin-beta4 4755073 8328237 Amir_4044 Actinosynnema mirum DSM 43827 Na-Ca exchanger/integrin-beta4 YP_003101751.1 4753130 D 446462 CDS YP_003101752.1 256378092 8328238 complement(4755135..4756883) 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rru:Rru_A2339 ABC transporter component; ABC transporter 4756883 8328238 Amir_4045 Actinosynnema mirum DSM 43827 ABC transporter YP_003101752.1 4755135 R 446462 CDS YP_003101753.1 256378093 8328239 complement(4756880..4758670) 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rru:Rru_A2340 ABC transporter, transmembrane region; ABC transporter 4758670 8328239 Amir_4046 Actinosynnema mirum DSM 43827 ABC transporter YP_003101753.1 4756880 R 446462 CDS YP_003101754.1 256378094 8328240 complement(4758797..4759492) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mlo:mlr7883 transcription regulator; TetR family transcriptional regulator 4759492 8328240 Amir_4047 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101754.1 4758797 R 446462 CDS YP_003101755.1 256378095 8328241 complement(4759524..4762004) 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: afw:Anae109_1773 hypothetical protein; hypothetical protein 4762004 8328241 Amir_4048 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101755.1 4759524 R 446462 CDS YP_003101756.1 256378096 8328242 complement(4762001..4762753) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0970 ABC transporter, ATPase subunit; ABC transporter 4762753 8328242 Amir_4049 Actinosynnema mirum DSM 43827 ABC transporter YP_003101756.1 4762001 R 446462 CDS YP_003101757.1 256378097 8328243 complement(4762762..4763181) 1 NC_013093.1 hypothetical protein 4763181 8328243 Amir_4050 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101757.1 4762762 R 446462 CDS YP_003101758.1 256378098 8328244 complement(4763398..4764075) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 4764075 8328244 Amir_4051 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101758.1 4763398 R 446462 CDS YP_003101759.1 256378099 8328245 complement(4764199..4765356) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: mmr:Mmar10_2544 signal transduction histidine kinase; histidine kinase 4765356 8328245 Amir_4052 Actinosynnema mirum DSM 43827 histidine kinase YP_003101759.1 4764199 R 446462 CDS YP_003101760.1 256378100 8328246 4765573..4765962 1 NC_013093.1 KEGG: afw:Anae109_4407 hypothetical protein; hypothetical protein 4765962 8328246 Amir_4053 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101760.1 4765573 D 446462 CDS YP_003101761.1 256378101 8328247 4765999..4766973 1 NC_013093.1 PFAM: Helix-turn-helix type 11 domain protein; protein of unknown function UPF0074; KEGG: afw:Anae109_3752 helix-turn-helix type 11 domain-containing protein; Helix-turn-helix type 11 domain-containing protein 4766973 8328247 Amir_4054 Actinosynnema mirum DSM 43827 Helix-turn-helix type 11 domain-containing protein YP_003101761.1 4765999 D 446462 CDS YP_003101762.1 256378102 8328248 4767068..4767517 1 NC_013093.1 KEGG: CG32198; hypothetical protein 4767517 8328248 Amir_4055 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101762.1 4767068 D 446462 CDS YP_003101763.1 256378103 8328249 complement(4767474..4768103) 1 NC_013093.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: bph:Bphy_6164 TetR family transcriptional regulator; TetR family transcriptional regulator 4768103 8328249 Amir_4056 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101763.1 4767474 R 446462 CDS YP_003101764.1 256378104 8328250 4768554..4769117 1 NC_013093.1 PFAM: protein of unknown function DUF1486; KEGG: cak:Caul_1308 hypothetical protein; hypothetical protein 4769117 8328250 Amir_4057 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101764.1 4768554 D 446462 CDS YP_003101765.1 256378105 8328251 4769121..4769897 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: bja:blr3078 hypothetical protein; beta-lactamase domain-containing protein 4769897 8328251 Amir_4058 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003101765.1 4769121 D 446462 CDS YP_003101766.1 256378106 8328253 complement(4772182..4772295) 1 NC_013093.1 hypothetical protein 4772295 8328253 Amir_4060 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101766.1 4772182 R 446462 CDS YP_003101767.1 256378107 8328254 complement(4772447..4773184) 1 NC_013093.1 hypothetical protein 4773184 8328254 Amir_4061 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101767.1 4772447 R 446462 CDS YP_003101768.1 256378108 8328257 complement(4775007..4775516) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bcn:Bcen_3699 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 4775516 8328257 Amir_4064 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101768.1 4775007 R 446462 CDS YP_003101769.1 256378109 8328258 complement(4775744..4776331) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: afw:Anae109_3254 TetR family transcriptional regulator; TetR family transcriptional regulator 4776331 8328258 Amir_4065 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101769.1 4775744 R 446462 CDS YP_003101770.1 256378110 8328261 complement(4778416..4780200) 1 NC_013093.1 KEGG: lch:Lcho_2475 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; histidine kinase 4780200 8328261 Amir_4068 Actinosynnema mirum DSM 43827 histidine kinase YP_003101770.1 4778416 R 446462 CDS YP_003101771.1 256378111 8328262 complement(4780190..4780888) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sus:Acid_5032 two component transcriptional regulator; winged helix family two component transcriptional regulator 4780888 8328262 Amir_4069 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003101771.1 4780190 R 446462 CDS YP_003101772.1 256378112 8328263 4780947..4782023 1 NC_013093.1 PFAM: peptidoglycan-binding domain 1 protein; KEGG: gur:Gura_3473 peptidoglycan binding domain- containing protein; peptidoglycan-binding domain 1 protein 4782023 8328263 Amir_4070 Actinosynnema mirum DSM 43827 peptidoglycan-binding domain 1 protein YP_003101772.1 4780947 D 446462 CDS YP_003101773.1 256378113 8328264 4782020..4782778 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: vco:VC0395_A1173 ABC transporter, ATP-binding protein; ABC transporter 4782778 8328264 Amir_4071 Actinosynnema mirum DSM 43827 ABC transporter YP_003101773.1 4782020 D 446462 CDS YP_003101774.1 256378114 8328265 4782775..4784049 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: gur:Gura_3474 ABC transporter; hypothetical protein 4784049 8328265 Amir_4072 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101774.1 4782775 D 446462 CDS YP_003101775.1 256378115 8328266 4784135..4784692 1 NC_013093.1 hypothetical protein 4784692 8328266 Amir_4073 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101775.1 4784135 D 446462 CDS YP_003101776.1 256378116 8328267 4784689..4785243 1 NC_013093.1 hypothetical protein 4785243 8328267 Amir_4074 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101776.1 4784689 D 446462 CDS YP_003101777.1 256378117 8328268 complement(4785299..4786501) 1 NC_013093.1 TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: spe:Spro_3869 cysteine desulfurase family protein; cysteine desulfurase family protein 4786501 8328268 Amir_4075 Actinosynnema mirum DSM 43827 cysteine desulfurase family protein YP_003101777.1 4785299 R 446462 CDS YP_003101778.1 256378118 8328269 4786835..4788385 1 NC_013093.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: scl:sce3486 choline dehydrogenase; glucose-methanol-choline oxidoreductase 4788385 8328269 Amir_4076 Actinosynnema mirum DSM 43827 glucose-methanol-choline oxidoreductase YP_003101778.1 4786835 D 446462 CDS YP_003101779.1 256378119 8328270 4788393..4789463 1 NC_013093.1 PFAM: O-methyltransferase; methyltransferase type 12; methyltransferase type 11; KEGG: sfu:Sfum_0920 O-methyltransferase, family 2; O-methyltransferase 4789463 8328270 Amir_4077 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003101779.1 4788393 D 446462 CDS YP_003101780.1 256378120 8328271 complement(4789499..4790074) 1 NC_013093.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: mxa:MXAN_3277 peroxidase, selenocysteine-containing; alkylhydroperoxidase like protein 4790074 8328271 Amir_4078 Actinosynnema mirum DSM 43827 alkylhydroperoxidase like protein YP_003101780.1 4789499 R 446462 CDS YP_003101781.1 256378121 8328272 complement(4790204..4790653) 1 NC_013093.1 KEGG: cbg:CbuG_0320 hypothetical membrane spanning protein; hypothetical protein 4790653 8328272 Amir_4079 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101781.1 4790204 R 446462 CDS YP_003101782.1 256378122 8328273 complement(4790664..4791674) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KR domain protein; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; KEGG: ade:Adeh_0777 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4791674 8328273 Amir_4080 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003101782.1 4790664 R 446462 CDS YP_003101783.1 256378123 8328274 complement(4791735..4792226) 1 NC_013093.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: pde:Pden_2689 flavin reductase domain protein, FMN-binding; flavin reductase domain-containing protein 4792226 8328274 Amir_4081 Actinosynnema mirum DSM 43827 flavin reductase domain-containing protein YP_003101783.1 4791735 R 446462 CDS YP_003101784.1 256378124 8328275 complement(4792223..4792681) 1 NC_013093.1 KEGG: pau:PA14_51770 hypothetical protein; hypothetical protein 4792681 8328275 Amir_4082 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101784.1 4792223 R 446462 CDS YP_003101785.1 256378125 8328276 complement(4792683..4798487) 1 NC_013093.1 PFAM: beta-ketoacyl synthase; acyl transferase; KR domain protein; short-chain dehydrogenase/reductase SDR; KEGG: mca:MCA1238 polyketide synthase; erythronolide synthase 4798487 8328276 Amir_4083 Actinosynnema mirum DSM 43827 erythronolide synthase YP_003101785.1 4792683 R 446462 CDS YP_003101786.1 256378126 8328277 complement(4798845..4800029) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: bur:Bcep18194_B1567 acyl-CoA dehydrogenase- like; acyl-CoA dehydrogenase type 2 domain-containing protein 4800029 8328277 Amir_4084 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003101786.1 4798845 R 446462 CDS YP_003101787.1 256378127 8328278 complement(4800084..4801268) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: bur:Bcep18194_B1567 acyl-CoA dehydrogenase- like; acyl-CoA dehydrogenase type 2 domain-containing protein 4801268 8328278 Amir_4085 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003101787.1 4800084 R 446462 CDS YP_003101788.1 256378128 8328279 complement(4801539..4802792) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: aha:AHA_1643 major facilitator transporter; major facilitator superfamily protein 4802792 8328279 Amir_4086 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101788.1 4801539 R 446462 CDS YP_003101789.1 256378129 8328280 4802988..4803509 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: sme:SMc02225 hypothetical protein; HxlR family transcriptional regulator 4803509 8328280 Amir_4087 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003101789.1 4802988 D 446462 CDS YP_003101790.1 256378130 8328281 complement(4803494..4804423) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: bja:blr8188 dehalogenase; alpha/beta hydrolase fold protein 4804423 8328281 Amir_4088 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101790.1 4803494 R 446462 CDS YP_003101791.1 256378131 8328282 complement(4804602..4805828) 1 NC_013093.1 KEGG: mxa:MXAN_0277 hypothetical protein; hypothetical protein 4805828 8328282 Amir_4089 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101791.1 4804602 R 446462 CDS YP_003101792.1 256378132 8328283 complement(4805992..4807317) 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: gbm:Gbem_1049 glycosyl transferase family 2; family 2 glycosyl transferase 4807317 8328283 Amir_4090 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003101792.1 4805992 R 446462 CDS YP_003101793.1 256378133 8328284 complement(4807459..4808637) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: bur:Bcep18194_B1567 acyl-CoA dehydrogenase- like; acyl-CoA dehydrogenase type 2 domain-containing protein 4808637 8328284 Amir_4091 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003101793.1 4807459 R 446462 CDS YP_003101794.1 256378134 8328285 complement(4808848..4810080) 1 NC_013093.1 PFAM: Epoxide hydrolase domain protein; alpha/beta hydrolase fold; KEGG: bja:bll7368 hydrolase; Epoxide hydrolase domain-containing protein 4810080 8328285 Amir_4092 Actinosynnema mirum DSM 43827 Epoxide hydrolase domain-containing protein YP_003101794.1 4808848 R 446462 CDS YP_003101795.1 256378135 8328286 complement(4810239..4811012) 1 NC_013093.1 PFAM: protein of unknown function DUF899 thioredoxin family protein; KEGG: pmy:Pmen_1335 protein of unknown function DUF899, thioredoxin family protein; hypothetical protein 4811012 8328286 Amir_4093 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101795.1 4810239 R 446462 CDS YP_003101796.1 256378136 8328287 complement(4811063..4812199) 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: bha:BH0710 hypothetical protein; oxidoreductase domain-containing protein 4812199 8328287 Amir_4094 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003101796.1 4811063 R 446462 CDS YP_003101797.1 256378137 8328288 4812666..4813643 1 NC_013093.1 KEGG: bpt:Bpet4347 hypothetical protein; hypothetical protein 4813643 8328288 Amir_4095 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101797.1 4812666 D 446462 CDS YP_003101798.1 256378138 8328289 complement(4813644..4814522) 1 NC_013093.1 hypothetical protein 4814522 8328289 Amir_4096 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101798.1 4813644 R 446462 CDS YP_003101799.1 256378139 8328290 4814805..4816121 1 NC_013093.1 PFAM: ABC-1 domain protein; KEGG: rsh:Rsph17029_0006 2-polyprenylphenol 6- hydroxylase; ABC transporter 4816121 8328290 Amir_4097 Actinosynnema mirum DSM 43827 ABC transporter YP_003101799.1 4814805 D 446462 CDS YP_003101800.1 256378140 8328291 4816129..4816764 1 NC_013093.1 TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: gur:Gura_3352 uncharacterized peroxidase- related enzyme; peroxidase 4816764 8328291 Amir_4098 Actinosynnema mirum DSM 43827 peroxidase YP_003101800.1 4816129 D 446462 CDS YP_003101801.1 256378141 8328292 4816761..4817639 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: msl:Msil_2581 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4817639 8328292 Amir_4099 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101801.1 4816761 D 446462 CDS YP_003101802.1 256378142 8328293 complement(4817745..4819292) 1 NC_013093.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: scl:sce3486 choline dehydrogenase; glucose-methanol-choline oxidoreductase 4819292 8328293 Amir_4100 Actinosynnema mirum DSM 43827 glucose-methanol-choline oxidoreductase YP_003101802.1 4817745 R 446462 CDS YP_003101803.1 256378143 8328294 4819509..4820495 1 NC_013093.1 PFAM: protein of unknown function DUF1702; hypothetical protein 4820495 8328294 Amir_4101 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101803.1 4819509 D 446462 CDS YP_003101804.1 256378144 8328295 4820492..4821850 1 NC_013093.1 PFAM: cytochrome P450; KEGG: mxa:MXAN_2304 cytochrome P450 family protein; cytochrome P450 4821850 8328295 Amir_4102 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101804.1 4820492 D 446462 CDS YP_003101805.1 256378145 8328296 4821883..4822911 1 NC_013093.1 KEGG: acp:A2cp1_3940 hypothetical protein; hypothetical protein 4822911 8328296 Amir_4103 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101805.1 4821883 D 446462 CDS YP_003101806.1 256378146 8328297 complement(4823000..4823752) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bha:BH0851 AraC/XylS family transcriptional regulator; AraC family transcriptional regulator 4823752 8328297 Amir_4104 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101806.1 4823000 R 446462 CDS YP_003101807.1 256378147 8328298 4824164..4824862 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rfr:Rfer_0325 TetR family transcriptional regulator; TetR family transcriptional regulator 4824862 8328298 Amir_4105 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101807.1 4824164 D 446462 CDS YP_003101808.1 256378148 8328300 complement(4825735..4826688) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: swi:Swit_1657 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 4826688 8328300 Amir_4107 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003101808.1 4825735 R 446462 CDS YP_003101809.1 256378149 8328301 4826774..4827343 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: cak:Caul_4437 TetR family transcriptional regulator; TetR family transcriptional regulator 4827343 8328301 Amir_4108 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101809.1 4826774 D 446462 CDS YP_003101810.1 256378150 8328302 complement(4827390..4827914) 1 NC_013093.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: pde:Pden_2689 flavin reductase domain protein, FMN-binding; flavin reductase domain-containing protein 4827914 8328302 Amir_4109 Actinosynnema mirum DSM 43827 flavin reductase domain-containing protein YP_003101810.1 4827390 R 446462 CDS YP_003101811.1 256378151 8328303 complement(4827911..4829209) 1 NC_013093.1 PFAM: acyl transferase; KEGG: dsh:Dshi_1963 beta-ketoacyl synthase; acyl transferase 4829209 8328303 Amir_4110 Actinosynnema mirum DSM 43827 acyl transferase YP_003101811.1 4827911 R 446462 CDS YP_003101812.1 256378152 8328304 complement(4829206..4830240) 1 NC_013093.1 KEGG: mxa:MXAN_7127 FG-GAP repeat protein; hypothetical protein 4830240 8328304 Amir_4111 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101812.1 4829206 R 446462 CDS YP_003101813.1 256378153 8328305 complement(4830237..4832240) 1 NC_013093.1 PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; KEGG: mxa:MXAN_7127 FG-GAP repeat protein; ASPIC/UnbV domain-containing protein 4832240 8328305 Amir_4112 Actinosynnema mirum DSM 43827 ASPIC/UnbV domain-containing protein YP_003101813.1 4830237 R 446462 CDS YP_003101814.1 256378154 8328306 complement(4832516..4833262) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rpi:Rpic_1138 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4833262 8328306 Amir_4113 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101814.1 4832516 R 446462 CDS YP_003101815.1 256378155 8328307 complement(4833383..4834081) 1 NC_013093.1 PFAM: protein of unknown function DUF899 thioredoxin family protein; KEGG: pmy:Pmen_1335 protein of unknown function DUF899, thioredoxin family protein; hypothetical protein 4834081 8328307 Amir_4114 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101815.1 4833383 R 446462 CDS YP_003101816.1 256378156 8328308 complement(4834113..4835666) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: dsh:Dshi_0253 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 4835666 8328308 Amir_4115 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101816.1 4834113 R 446462 CDS YP_003101817.1 256378157 8328309 complement(4835663..4836493) 1 NC_013093.1 catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA; p-hydroxycinnamoyl CoA hydratase/lyase 4836493 8328309 Amir_4116 Actinosynnema mirum DSM 43827 p-hydroxycinnamoyl CoA hydratase/lyase YP_003101817.1 4835663 R 446462 CDS YP_003101818.1 256378158 8328310 4836901..4838868 1 NC_013093.1 PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; KEGG: mxa:MXAN_7127 FG-GAP repeat protein; ASPIC/UnbV domain-containing protein 4838868 8328310 Amir_4117 Actinosynnema mirum DSM 43827 ASPIC/UnbV domain-containing protein YP_003101818.1 4836901 D 446462 CDS YP_003101819.1 256378159 8328311 4838906..4839967 1 NC_013093.1 KEGG: mxa:MXAN_7127 FG-GAP repeat protein; hypothetical protein 4839967 8328311 Amir_4118 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101819.1 4838906 D 446462 CDS YP_003101820.1 256378160 8328312 complement(4840147..4840935) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bha:BH0851 AraC/XylS family transcriptional regulator; AraC family transcriptional regulator 4840935 8328312 Amir_4119 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003101820.1 4840147 R 446462 CDS YP_003101821.1 256378161 8328313 4841924..4842496 1 NC_013093.1 hypothetical protein 4842496 8328313 Amir_4120 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101821.1 4841924 D 446462 CDS YP_003101822.1 256378162 8328314 4842501..4844030 1 NC_013093.1 KEGG: GK18511 gene product from transcript GK18511- RA; hypothetical protein 4844030 8328314 Amir_4121 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101822.1 4842501 D 446462 CDS YP_003101823.1 256378163 8328315 4844163..4845989 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: azc:AZC_2089 hypothetical protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4845989 8328315 Amir_4122 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003101823.1 4844163 D 446462 CDS YP_003101824.1 256378164 8328316 4846114..4847415 1 NC_013093.1 PFAM: PEP-utilizing protein; KEGG: ccs:CCNA_00571 phosphoenolpyruvate-protein phosphotransferase/phosphocarrier protein HPr/PTS system, glucose-specific IIA subunit; PEP-utilizing protein 4847415 8328316 Amir_4123 Actinosynnema mirum DSM 43827 PEP-utilizing protein YP_003101824.1 4846114 D 446462 CDS YP_003101825.1 256378165 8328317 complement(4847422..4849437) 1 NC_013093.1 KEGG: ade:Adeh_3102 molybdopterin-binding xanthine dehydrogenase; isoquinoline 1-oxidoreductase 4849437 8328317 Amir_4124 Actinosynnema mirum DSM 43827 isoquinoline 1-oxidoreductase YP_003101825.1 4847422 R 446462 CDS YP_003101826.1 256378166 8328318 complement(4849434..4849898) 1 NC_013093.1 PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: mxa:MXAN_1751 isoquinoline 1-oxidoreductase, alpha subunit; (2Fe-2S)-binding domain-containing protein 4849898 8328318 Amir_4125 Actinosynnema mirum DSM 43827 (2Fe-2S)-binding domain-containing protein YP_003101826.1 4849434 R 446462 CDS YP_003101827.1 256378167 8328319 4850121..4850249 1 NC_013093.1 hypothetical protein 4850249 8328319 Amir_4126 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101827.1 4850121 D 446462 CDS YP_003101828.1 256378168 8328320 complement(4850429..4853086) 1 NC_013093.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: scl:sce2990 hypothetical protein; SNF2-like protein 4853086 8328320 Amir_4127 Actinosynnema mirum DSM 43827 SNF2-like protein YP_003101828.1 4850429 R 446462 CDS YP_003101829.1 256378169 8328321 4853202..4856597 1 NC_013093.1 PFAM: helicase domain protein; SNF2-related protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicase; KEGG: xau:Xaut_2988 helicase domain-containing protein; helicase domain-containing protein 4856597 8328321 Amir_4128 Actinosynnema mirum DSM 43827 helicase domain-containing protein YP_003101829.1 4853202 D 446462 CDS YP_003101830.1 256378170 8328322 complement(4856688..4857368) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4857368 8328322 Amir_4129 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101830.1 4856688 R 446462 CDS YP_003101831.1 256378171 8328323 complement(4857632..4858666) 1 NC_013093.1 KEGG: scl:sce0662 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 4858666 8328323 Amir_4130 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003101831.1 4857632 R 446462 CDS YP_003101832.1 256378172 8328324 4858782..4860689 1 NC_013093.1 KEGG: scl:sce0661 mannan endo-1,4-beta-mannosidase; mannan endo-1,4-beta-mannosidase 4860689 8328324 Amir_4131 Actinosynnema mirum DSM 43827 mannan endo-1,4-beta-mannosidase YP_003101832.1 4858782 D 446462 CDS YP_003101833.1 256378173 8328325 4860686..4861909 1 NC_013093.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: ccs:CCNA_02903 starvation sensing protein RspA; mandelate racemase/muconate lactonizing protein 4861909 8328325 Amir_4132 Actinosynnema mirum DSM 43827 mandelate racemase/muconate lactonizing protein YP_003101833.1 4860686 D 446462 CDS YP_003101834.1 256378174 8328326 4862064..4862561 1 NC_013093.1 hypothetical protein 4862561 8328326 Amir_4133 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101834.1 4862064 D 446462 CDS YP_003101835.1 256378175 8328327 4862679..4864289 1 NC_013093.1 PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: scl:sce2212 topoisomerase; cellulose-binding family protein 4864289 8328327 Amir_4134 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003101835.1 4862679 D 446462 CDS YP_003101836.1 256378176 8328328 complement(4864350..4865732) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: met:M446_1000 hypothetical protein; FAD-binding monooxygenase 4865732 8328328 Amir_4135 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101836.1 4864350 R 446462 CDS YP_003101837.1 256378177 8328329 complement(4866204..4866674) 1 NC_013093.1 PFAM: calcium/calmodulin dependent protein kinase II association-domain protein; KEGG: pfl:PFL_3821 hypothetical protein; calcium/calmodulin dependent protein kinase II association-domain-containing protein 4866674 8328329 Amir_4136 Actinosynnema mirum DSM 43827 calcium/calmodulin dependent protein kinase II association-domain-containing protein YP_003101837.1 4866204 R 446462 CDS YP_003101838.1 256378178 8328330 complement(4866773..4868119) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: ppu:PP_4505 integral membrane sensor signal transduction histidine kinase; histidine kinase 4868119 8328330 Amir_4137 Actinosynnema mirum DSM 43827 histidine kinase YP_003101838.1 4866773 R 446462 CDS YP_003101839.1 256378179 8328331 complement(4868119..4868856) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bte:BTH_II1765 DNA-binding response regulator; winged helix family two component transcriptional regulator 4868856 8328331 Amir_4138 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003101839.1 4868119 R 446462 CDS YP_003101840.1 256378180 8328332 complement(4869007..4870872) 1 NC_013093.1 KEGG: fibrocystin-L-like protein; hypothetical protein 4870872 8328332 Amir_4139 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101840.1 4869007 R 446462 CDS YP_003101841.1 256378181 8328333 complement(4870916..4871779) 1 NC_013093.1 hypothetical protein 4871779 8328333 Amir_4140 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101841.1 4870916 R 446462 CDS YP_003101842.1 256378182 8328334 complement(4872275..4874623) 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: bps:BPSL0571 hypothetical protein; aminoglycoside phosphotransferase 4874623 8328334 Amir_4141 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003101842.1 4872275 R 446462 CDS YP_003101843.1 256378183 8328335 complement(4874586..4875404) 1 NC_013093.1 KEGG: dac:Daci_2301 hypothetical protein; hypothetical protein 4875404 8328335 Amir_4142 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101843.1 4874586 R 446462 CDS YP_003101844.1 256378184 8328336 complement(4875413..4876252) 1 NC_013093.1 SMART: von Willebrand factor type A; KEGG: dac:Daci_2300 hypothetical protein; von Willebrand factor type A 4876252 8328336 Amir_4143 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003101844.1 4875413 R 446462 CDS YP_003101845.1 256378185 8328337 4876453..4877442 1 NC_013093.1 PFAM: pirin; KEGG: pap:PSPA7_4173 hypothetical protein; pirin 4877442 8328337 Amir_4144 Actinosynnema mirum DSM 43827 pirin YP_003101845.1 4876453 D 446462 CDS YP_003101846.1 256378186 8328338 complement(4877596..4879023) 1 NC_013093.1 KEGG: mxa:MXAN_0224 hypothetical protein; hypothetical protein 4879023 8328338 Amir_4145 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101846.1 4877596 R 446462 CDS YP_003101847.1 256378187 8328339 4879355..4879603 1 NC_013093.1 hypothetical protein 4879603 8328339 Amir_4146 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101847.1 4879355 D 446462 CDS YP_003101848.1 256378188 8328340 4879564..4879800 1 NC_013093.1 hypothetical protein 4879800 8328340 Amir_4147 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101848.1 4879564 D 446462 CDS YP_003101849.1 256378189 8328341 4879912..4880748 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sml:Smlt0507 arylesterase (aryl- ester hydrolase); alpha/beta hydrolase fold protein 4880748 8328341 Amir_4148 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101849.1 4879912 D 446462 CDS YP_003101850.1 256378190 8328342 complement(4880803..4881765) 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: dsh:Dshi_3592 Cna B domain-containing protein; Ricin B lectin 4881765 8328342 Amir_4149 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101850.1 4880803 R 446462 CDS YP_003101851.1 256378191 8328343 complement(4882198..4883199) 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: hypothetical protein; Ricin B lectin 4883199 8328343 Amir_4150 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101851.1 4882198 R 446462 CDS YP_003101852.1 256378192 8328344 complement(4883864..4884826) 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: hdu:HD0746 endo-1,4-beta-xylanase A; Ricin B lectin 4884826 8328344 Amir_4151 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101852.1 4883864 R 446462 CDS YP_003101853.1 256378193 8328345 complement(4885000..4886349) 1 NC_013093.1 PFAM: cellulose-binding family II; glycoside hydrolase family 5; SMART: cellulose-binding family II; KEGG: sde:Sde_0064 secreted beta- mannosidase; cellulose-binding family protein 4886349 8328345 Amir_4152 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003101853.1 4885000 R 446462 CDS YP_003101854.1 256378194 8328346 complement(4886550..4888169) 1 NC_013093.1 KEGG: mno:Mnod_3288 hypothetical protein; hypothetical protein 4888169 8328346 Amir_4153 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101854.1 4886550 R 446462 CDS YP_003101855.1 256378195 8328347 4888507..4890438 1 NC_013093.1 KEGG: pap:PSPA7_4431 hypothetical protein; hypothetical protein 4890438 8328347 Amir_4154 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101855.1 4888507 D 446462 CDS YP_003101856.1 256378196 8328348 4890557..4891486 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: bvi:Bcep1808_2033 allergen V5/TPX-1 family protein; G-D-S-L family lipolytic protein 4891486 8328348 Amir_4155 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003101856.1 4890557 D 446462 CDS YP_003101857.1 256378197 8328349 4891759..4892562 1 NC_013093.1 KEGG: hypothetical LOC100006405; hypothetical protein 4892562 8328349 Amir_4156 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101857.1 4891759 D 446462 CDS YP_003101858.1 256378198 8328350 4892613..4893224 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4893224 8328350 Amir_4157 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101858.1 4892613 D 446462 CDS YP_003101859.1 256378199 8328351 4893344..4893847 1 NC_013093.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4893847 8328351 Amir_4158 Actinosynnema mirum DSM 43827 methionine sulfoxide reductase A YP_003101859.1 4893344 D 446462 CDS YP_003101860.1 256378200 8328352 complement(4894193..4895020) 1 NC_013093.1 KEGG: rme:Rmet_4144 citrate synthase; citrate synthase 4895020 8328352 Amir_4159 Actinosynnema mirum DSM 43827 citrate synthase YP_003101860.1 4894193 R 446462 CDS YP_003101861.1 256378201 8328353 complement(4895017..4896240) 1 NC_013093.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rme:Rmet_4145 L-carnitine dehydratase/bile acid-inducible protein F; L-carnitine dehydratase/bile acid-inducible protein F 4896240 8328353 Amir_4160 Actinosynnema mirum DSM 43827 L-carnitine dehydratase/bile acid-inducible protein F YP_003101861.1 4895017 R 446462 CDS YP_003101862.1 256378202 8328354 complement(4896237..4897748) 1 NC_013093.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: bpt:Bpet0754 hypothetical protein; hypothetical protein 4897748 8328354 Amir_4161 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101862.1 4896237 R 446462 CDS YP_003101863.1 256378203 8328355 complement(4897748..4898335) 1 NC_013093.1 KEGG: bja:blr3162 hypothetical protein; hypothetical protein 4898335 8328355 Amir_4162 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101863.1 4897748 R 446462 CDS YP_003101864.1 256378204 8328356 complement(4898332..4899318) 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: oan:Oant_3917 uncharacterized protein UPF0065; hypothetical protein 4899318 8328356 Amir_4163 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101864.1 4898332 R 446462 CDS YP_003101865.1 256378205 8328357 4899456..4900235 1 NC_013093.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: cti:RALTA_B1947 transcriptional regulator, IclR family; IclR family transcriptional regulator 4900235 8328357 Amir_4164 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003101865.1 4899456 D 446462 CDS YP_003101866.1 256378206 8328358 4900292..4900882 1 NC_013093.1 PFAM: Dimethylmenaquinone methyltransferase; KEGG: mrd:Mrad2831_3497 dimethylmenaquinone methyltransferase; Dimethylmenaquinone methyltransferase 4900882 8328358 Amir_4165 Actinosynnema mirum DSM 43827 Dimethylmenaquinone methyltransferase YP_003101866.1 4900292 D 446462 CDS YP_003101867.1 256378207 8328359 4900890..4901810 1 NC_013093.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: ppf:Pput_1368 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 4901810 8328359 Amir_4166 Actinosynnema mirum DSM 43827 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_003101867.1 4900890 D 446462 CDS YP_003101868.1 256378208 8328360 complement(4902799..4903947) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4903947 8328360 Amir_4167 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101868.1 4902799 R 446462 CDS YP_003101869.1 256378209 8328361 complement(4904208..4905146) 1 NC_013093.1 PFAM: protein of unknown function DUF1177; KEGG: vei:Veis_1102 protein of unknown function DUF1177; hypothetical protein 4905146 8328361 Amir_4168 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101869.1 4904208 R 446462 CDS YP_003101870.1 256378210 8328362 complement(4905242..4905883) 1 NC_013093.1 PFAM: Asp/Glu/hydantoin racemase; KEGG: jan:Jann_1486 Asp/Glu racemase; Asp/Glu/hydantoin racemase 4905883 8328362 Amir_4169 Actinosynnema mirum DSM 43827 Asp/Glu/hydantoin racemase YP_003101870.1 4905242 R 446462 CDS YP_003101871.1 256378211 8328363 complement(4905880..4906599) 1 NC_013093.1 PFAM: AroM family protein; KEGG: spe:Spro_1025 hypothetical protein; AroM family protein 4906599 8328363 Amir_4170 Actinosynnema mirum DSM 43827 AroM family protein YP_003101871.1 4905880 R 446462 CDS YP_003101872.1 256378212 8328364 complement(4906592..4908292) 1 NC_013093.1 PFAM: Oligopeptide transporter OPT superfamily protein; KEGG: vei:Veis_1103 oligopeptide transporter OPT superfamily protein; Oligopeptide transporter OPT superfamily protein 4908292 8328364 Amir_4171 Actinosynnema mirum DSM 43827 Oligopeptide transporter OPT superfamily protein YP_003101872.1 4906592 R 446462 CDS YP_003101873.1 256378213 8328365 complement(4908305..4909054) 1 NC_013093.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: reu:Reut_B5545 regulatory protein, IclR; IclR family transcriptional regulator 4909054 8328365 Amir_4172 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003101873.1 4908305 R 446462 CDS YP_003101874.1 256378214 8328366 4909181..4909930 1 NC_013093.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4909930 8328366 Amir_4173 Actinosynnema mirum DSM 43827 peptidase E YP_003101874.1 4909181 D 446462 CDS YP_003101875.1 256378215 8328367 4910160..4911641 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; cellulose-binding family II; SMART: serine/threonine protein kinase; cellulose- binding family II; tyrosine protein kinase; KEGG: acp:A2cp1_2229 serine/threonine protein kinase with TPR repeats; serine/threonine protein kinase 4911641 8328367 Amir_4174 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003101875.1 4910160 D 446462 CDS YP_003101876.1 256378216 8328368 4911853..4913475 1 NC_013093.1 hypothetical protein 4913475 8328368 Amir_4175 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101876.1 4911853 D 446462 CDS YP_003101877.1 256378217 8328369 4913829..4915280 1 NC_013093.1 hypothetical protein 4915280 8328369 Amir_4176 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101877.1 4913829 D 446462 CDS YP_003101878.1 256378218 8328370 complement(4915343..4916635) 1 NC_013093.1 PFAM: pectate lyase; Ricin B lectin; SMART: Ricin B lectin; KEGG: hypothetical protein; pectate lyase 4916635 8328370 Amir_4177 Actinosynnema mirum DSM 43827 pectate lyase YP_003101878.1 4915343 R 446462 CDS YP_003101879.1 256378219 8328371 complement(4916834..4917778) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: msl:Msil_0872 alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase GroES domain-containing protein 4917778 8328371 Amir_4178 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003101879.1 4916834 R 446462 CDS YP_003101880.1 256378220 8328372 4917920..4918420 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: abo:ABO_0014 MarR family transcriptional regulator; MarR family transcriptional regulator 4918420 8328372 Amir_4179 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003101880.1 4917920 D 446462 CDS YP_003101881.1 256378221 8328373 4918488..4919435 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: similar to D-aspartate oxidase; K00272 D- aspartate oxidase; D-aspartate oxidase 4919435 8328373 Amir_4180 Actinosynnema mirum DSM 43827 D-aspartate oxidase YP_003101881.1 4918488 D 446462 CDS YP_003101882.1 256378222 8328374 4919670..4920449 1 NC_013093.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: afw:Anae109_1933 methionine aminopeptidase, type I; methionine aminopeptidase, type I 4920449 8328374 Amir_4181 Actinosynnema mirum DSM 43827 methionine aminopeptidase, type I YP_003101882.1 4919670 D 446462 CDS YP_003101883.1 256378223 8328375 complement(4920537..4922609) 1 NC_013093.1 SMART: ATPase AAA; hypothetical protein; KEGG: scl:sce5225 protein kinase; ATPase AAA 4922609 8328375 Amir_4182 Actinosynnema mirum DSM 43827 ATPase AAA YP_003101883.1 4920537 R 446462 CDS YP_003101884.1 256378224 8328376 complement(4922638..4924287) 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: bcu:BCAH820_0093 DNA-binding protein; hypothetical protein 4924287 8328376 Amir_4183 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101884.1 4922638 R 446462 CDS YP_003101885.1 256378225 8328377 4924654..4926264 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 4926264 8328377 Amir_4184 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003101885.1 4924654 D 446462 CDS YP_003101886.1 256378226 8328378 complement(4926336..4927892) 1 NC_013093.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: abo:ABO_1940 apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 4927892 8328378 Amir_4185 Actinosynnema mirum DSM 43827 apolipoprotein N-acyltransferase YP_003101886.1 4926336 R 446462 CDS YP_003101887.1 256378227 8328379 complement(4927987..4929573) 1 NC_013093.1 KEGG: met:M446_3732 von Willebrand factor type A; hypothetical protein 4929573 8328379 Amir_4186 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101887.1 4927987 R 446462 CDS YP_003101888.1 256378228 8328380 complement(4929747..4930685) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: oxidoreductase protein; short chain dehydrogenase 4930685 8328380 Amir_4187 Actinosynnema mirum DSM 43827 short chain dehydrogenase YP_003101888.1 4929747 R 446462 CDS YP_003101889.1 256378229 8328381 4930876..4931772 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; XRE family transcriptional regulator 4931772 8328381 Amir_4188 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003101889.1 4930876 D 446462 CDS YP_003101890.1 256378230 8328382 complement(4931836..4932681) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: alpha/beta hydrolase protein; alpha/beta hydrolase fold protein 4932681 8328382 Amir_4189 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101890.1 4931836 R 446462 CDS YP_003101891.1 256378231 8328383 4932779..4933255 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: scl:sce8843 MarR family transcriptional regulator; MarR family transcriptional regulator 4933255 8328383 Amir_4190 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003101891.1 4932779 D 446462 CDS YP_003101892.1 256378232 8328384 4933363..4934979 1 NC_013093.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 4934979 8328384 Amir_4191 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003101892.1 4933363 D 446462 CDS YP_003101893.1 256378233 8328385 4935123..4935548 1 NC_013093.1 PFAM: ferric-uptake regulator; KEGG: hhe:HH0942 transcriptional regulator; Fur family ferric uptake regulator 4935548 8328385 Amir_4192 Actinosynnema mirum DSM 43827 Fur family ferric uptake regulator YP_003101893.1 4935123 D 446462 CDS YP_003101894.1 256378234 8328386 4935633..4937861 1 NC_013093.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: pol:Bpro_0678 catalase/peroxidase HPI; catalase/peroxidase HPI 4937861 8328386 Amir_4193 Actinosynnema mirum DSM 43827 catalase/peroxidase HPI YP_003101894.1 4935633 D 446462 CDS YP_003101895.1 256378235 8328387 complement(4938033..4941230) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: she:Shewmr4_1596 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 4941230 8328387 Amir_4194 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003101895.1 4938033 R 446462 CDS YP_003101896.1 256378236 8328388 complement(4941518..4944778) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: she:Shewmr4_1596 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 4944778 8328388 Amir_4195 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003101896.1 4941518 R 446462 CDS YP_003101897.1 256378237 8328389 complement(4945227..4947227) 1 NC_013093.1 TIGRFAM: hypothetical protein; PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein 4947227 8328389 Amir_4196 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101897.1 4945227 R 446462 CDS YP_003101898.1 256378238 8328390 4947433..4947585 1 NC_013093.1 hypothetical protein 4947585 8328390 Amir_4197 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101898.1 4947433 D 446462 CDS YP_003101899.1 256378239 8328391 4947727..4949190 1 NC_013093.1 KEGG: xca:xccb100_0130 exported pectinesterase; PFAM: pectinesterase; Ricin B lectin; SMART: Ricin B lectin; pectinesterase 4949190 8328391 Amir_4198 Actinosynnema mirum DSM 43827 pectinesterase YP_003101899.1 4947727 D 446462 CDS YP_003101900.1 256378240 8328392 4949211..4950635 1 NC_013093.1 PFAM: Ricin B lectin; pectate lyase/Amb allergen; SMART: Ricin B lectin; Parallel beta-helix repeat; pectate lyase/Amb allergen; KEGG: bha:BH0698 pectate lyase; Ricin B lectin 4950635 8328392 Amir_4199 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003101900.1 4949211 D 446462 CDS YP_003101901.1 256378241 8328393 4950817..4951386 1 NC_013093.1 hypothetical protein 4951386 8328393 Amir_4200 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101901.1 4950817 D 446462 CDS YP_003101902.1 256378242 8328394 complement(4951417..4952217) 1 NC_013093.1 catalyzes the formation of precorrin 6x from precorrin 5; precorrin 6A synthase 4952217 8328394 Amir_4201 Actinosynnema mirum DSM 43827 precorrin 6A synthase YP_003101902.1 4951417 R 446462 CDS YP_003101903.1 256378243 8328395 complement(4952264..4952878) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: sus:Acid_4679 TetR family transcriptional regulator; TetR family transcriptional regulator 4952878 8328395 Amir_4202 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101903.1 4952264 R 446462 CDS YP_003101904.1 256378244 8328396 4952923..4954386 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: bsu:BSU10500 hypothetical protein; FAD-binding monooxygenase 4954386 8328396 Amir_4203 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101904.1 4952923 D 446462 CDS YP_003101905.1 256378245 8328397 complement(4954489..4955736) 1 NC_013093.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 4955736 8328397 Amir_4204 Actinosynnema mirum DSM 43827 diaminobutyrate--2-oxoglutarate aminotransferase YP_003101905.1 4954489 R 446462 CDS YP_003101906.1 256378246 8328398 complement(4955816..4956940) 1 NC_013093.1 KEGG: bmj:BMULJ_04091 APA family basic amino acid/polyamine antiporter; APA family basic amino acid/polyamine antiporter 4956940 8328398 Amir_4205 Actinosynnema mirum DSM 43827 APA family basic amino acid/polyamine antiporter YP_003101906.1 4955816 R 446462 CDS YP_003101907.1 256378247 8328399 complement(4956937..4958292) 1 NC_013093.1 KEGG: rso:RSp1425 L-ornithine 5-monooxygenase oxidoreductase protein; L-ornithine 5-monooxygenase oxidoreductase protein 4958292 8328399 Amir_4206 Actinosynnema mirum DSM 43827 L-ornithine 5-monooxygenase oxidoreductase protein YP_003101907.1 4956937 R 446462 CDS YP_003101908.1 256378248 8328400 complement(4958336..4959415) 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: bpy:Bphyt_0284 FAD dependent oxidoreductase; FAD dependent oxidoreductase 4959415 8328400 Amir_4207 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003101908.1 4958336 R 446462 CDS YP_003101909.1 256378249 8328401 complement(4959412..4961349) 1 NC_013093.1 PFAM: tRNA synthetase class I (M); cupin; KEGG: pen:PSEEN0982 methionine--tRNA ligase; methionine--tRNA ligase 4961349 8328401 Amir_4208 Actinosynnema mirum DSM 43827 methionine--tRNA ligase YP_003101909.1 4959412 R 446462 CDS YP_003101910.1 256378250 8328402 complement(4961555..4962097) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4962097 8328402 Amir_4209 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101910.1 4961555 R 446462 CDS YP_003101911.1 256378251 8328403 complement(4962201..4963190) 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: tmz:Tmz1t_1271 hypothetical protein; hypothetical protein 4963190 8328403 Amir_4210 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101911.1 4962201 R 446462 CDS YP_003101912.1 256378252 8328404 complement(4963227..4964516) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: rso:RS03119 transmembrane protein; FAD-binding monooxygenase 4964516 8328404 Amir_4211 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003101912.1 4963227 R 446462 CDS YP_003101913.1 256378253 8328405 complement(4964563..4965288) 1 NC_013093.1 PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: rso:RS03114 hypothetical protein; rhodanese domain-containing protein 4965288 8328405 Amir_4212 Actinosynnema mirum DSM 43827 rhodanese domain-containing protein YP_003101913.1 4964563 R 446462 CDS YP_003101914.1 256378254 8328406 complement(4965298..4966953) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS03108 hypothetical protein; AMP-dependent synthetase and ligase 4966953 8328406 Amir_4213 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003101914.1 4965298 R 446462 CDS YP_003101915.1 256378255 8328407 complement(4966937..4967851) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: rso:RS03113 esterase protein; alpha/beta hydrolase fold-3 domain-containing protein 4967851 8328407 Amir_4214 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold-3 domain-containing protein YP_003101915.1 4966937 R 446462 CDS YP_003101916.1 256378256 8328408 complement(4967856..4969499) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS03108 hypothetical protein; amino acid adenylation domain-containing protein 4969499 8328408 Amir_4215 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003101916.1 4967856 R 446462 CDS YP_003101917.1 256378257 8328409 complement(4969496..4969954) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rso:RS03106 acetyltransferase protein; GCN5-like N-acetyltransferase 4969954 8328409 Amir_4216 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003101917.1 4969496 R 446462 CDS YP_003101918.1 256378258 8328410 complement(4969966..4970487) 1 NC_013093.1 KEGG: rso:RS03105 hypothetical protein; hypothetical protein 4970487 8328410 Amir_4217 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101918.1 4969966 R 446462 CDS YP_003101919.1 256378259 8328411 4971419..4972321 1 NC_013093.1 PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: aha:AHA_4117 regulatory protein, LysR:LysR, substrate-binding; LysR family transcriptional regulator 4972321 8328411 Amir_4218 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003101919.1 4971419 D 446462 CDS YP_003101920.1 256378260 8328412 4972422..4973201 1 NC_013093.1 PFAM: inositol monophosphatase; KEGG: rru:Rru_A1076 inositol monophosphatase; inositol monophosphatase 4973201 8328412 Amir_4219 Actinosynnema mirum DSM 43827 inositol monophosphatase YP_003101920.1 4972422 D 446462 CDS YP_003101921.1 256378261 8328413 4973198..4973830 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: dsh:Dshi_0026 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4973830 8328413 Amir_4220 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003101921.1 4973198 D 446462 CDS YP_003101922.1 256378262 8328414 4974321..4974875 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4974875 8328414 Amir_4221 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101922.1 4974321 D 446462 CDS YP_003101923.1 256378263 8328415 4974882..4975214 1 NC_013093.1 hypothetical protein 4975214 8328415 Amir_4222 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101923.1 4974882 D 446462 CDS YP_003101924.1 256378264 8328416 4975211..4976107 1 NC_013093.1 KEGG: GK21128 gene product from transcript GK21128- RA; hypothetical protein 4976107 8328416 Amir_4223 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101924.1 4975211 D 446462 CDS YP_003101925.1 256378265 8328417 complement(4976219..4976980) 1 NC_013093.1 hypothetical protein 4976980 8328417 Amir_4224 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101925.1 4976219 R 446462 CDS YP_003101926.1 256378266 8328418 4977378..4979276 1 NC_013093.1 PFAM: glycoside hydrolase family 5; KEGG: hypothetical protein; glycoside hydrolase family protein 4979276 8328418 Amir_4225 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003101926.1 4977378 D 446462 CDS YP_003101927.1 256378267 8328419 4979319..4980107 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 4980107 8328419 Amir_4226 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101927.1 4979319 D 446462 CDS YP_003101928.1 256378268 8328420 4980190..4980525 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bcz:pE33L466_0439 transcriptional regulator; ArsR family transcriptional regulator 4980525 8328420 Amir_4227 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003101928.1 4980190 D 446462 CDS YP_003101929.1 256378269 8328421 4980522..4982132 1 NC_013093.1 PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; KEGG: net:Neut_0352 sulphate transporter; sulfate transporter 4982132 8328421 Amir_4228 Actinosynnema mirum DSM 43827 sulfate transporter YP_003101929.1 4980522 D 446462 CDS YP_003101930.1 256378270 8328422 complement(4982163..4982939) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: atc:AGR_pAT_269 hypothetical protein; MerR family transcriptional regulator 4982939 8328422 Amir_4229 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003101930.1 4982163 R 446462 CDS YP_003101931.1 256378271 8328423 4983064..4983708 1 NC_013093.1 hypothetical protein 4983708 8328423 Amir_4230 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101931.1 4983064 D 446462 CDS YP_003101932.1 256378272 8328424 complement(4983795..4984361) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bcm:Bcenmc03_5854 hypothetical protein; TetR family transcriptional regulator 4984361 8328424 Amir_4231 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101932.1 4983795 R 446462 CDS YP_003101933.1 256378273 8328425 4984434..4984913 1 NC_013093.1 hypothetical protein 4984913 8328425 Amir_4232 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101933.1 4984434 D 446462 CDS YP_003101934.1 256378274 8328426 4984945..4985376 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 4985376 8328426 Amir_4233 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003101934.1 4984945 D 446462 CDS YP_003101935.1 256378275 8328427 4985692..4986588 1 NC_013093.1 TIGRFAM: methyltransferase; PFAM: O-methyltransferase; KEGG: bur:Bcep18194_B1573 protein of unknown function Mtu_121; methyltransferase 4986588 8328427 Amir_4234 Actinosynnema mirum DSM 43827 methyltransferase YP_003101935.1 4985692 D 446462 CDS YP_003101936.1 256378276 8328428 4986728..4987930 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bca:BCE_2696 cytochrome P450; cytochrome P450 4987930 8328428 Amir_4235 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003101936.1 4986728 D 446462 CDS YP_003101937.1 256378277 8328429 4988138..4989745 1 NC_013093.1 KEGG: sus:Acid_0740 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; RecQ family ATP-dependent DNA helicase 4989745 8328429 Amir_4236 Actinosynnema mirum DSM 43827 RecQ family ATP-dependent DNA helicase YP_003101937.1 4988138 D 446462 CDS YP_003101938.1 256378278 8328430 4989937..4990638 1 NC_013093.1 PFAM: glycoside hydrolase family 11; KEGG: sde:Sde_3061 xylanase/chitin deacetylase-like; endo-1,4-beta-xylanase 4990638 8328430 Amir_4237 Actinosynnema mirum DSM 43827 endo-1,4-beta-xylanase YP_003101938.1 4989937 D 446462 CDS YP_003101939.1 256378279 8328431 complement(4990794..4996277) 1 NC_013093.1 PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; carboxyl transferase; biotin/lipoyl attachment domain- containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: aba:Acid345_0466 carbamoyl-phosphate synthase L chain, ATP-binding; carbamoyl-phosphate synthase L chain ATP- binding 4996277 8328431 Amir_4238 Actinosynnema mirum DSM 43827 carbamoyl-phosphate synthase L chain ATP- binding YP_003101939.1 4990794 R 446462 CDS YP_003101940.1 256378280 8328432 complement(4996684..4997490) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_2483 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 4997490 8328432 Amir_4239 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003101940.1 4996684 R 446462 CDS YP_003101941.1 256378281 8328433 complement(4997487..4998392) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: xfm:Xfasm12_1606 ABC transporter sugar permease; ABC transporter inner membrane protein 4998392 8328433 Amir_4240 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003101941.1 4997487 R 446462 CDS YP_003101942.1 256378282 8328434 complement(4998389..4999657) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: sit:TM1040_3216 extracellular solute-binding protein; family 1 extracellular solute-binding protein 4999657 8328434 Amir_4241 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003101942.1 4998389 R 446462 CDS YP_003101943.1 256378283 8328435 5000032..5000559 1 NC_013093.1 hypothetical protein 5000559 8328435 Amir_4242 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101943.1 5000032 D 446462 CDS YP_003101944.1 256378284 8328436 complement(5000650..5001642) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: cak:Caul_4616 aldo/keto reductase; aldo/keto reductase 5001642 8328436 Amir_4243 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003101944.1 5000650 R 446462 CDS YP_003101945.1 256378285 8328437 5001773..5002636 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: rle:RL4049 hypothetical protein; helix-turn-helix domain-containing protein 5002636 8328437 Amir_4244 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003101945.1 5001773 D 446462 CDS YP_003101946.1 256378286 8328438 5002809..5003219 1 NC_013093.1 KEGG: sml:Smlt3526 outer membrane lipoprotein; hypothetical protein 5003219 8328438 Amir_4245 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101946.1 5002809 D 446462 CDS YP_003101947.1 256378287 8328439 complement(5003295..5004182) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aav:Aave_0303 transcriptional regulator, LysR family; LysR family transcriptional regulator 5004182 8328439 Amir_4246 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003101947.1 5003295 R 446462 CDS YP_003101948.1 256378288 8328440 complement(5004188..5005015) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: rpb:RPB_0526 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 5005015 8328440 Amir_4247 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003101948.1 5004188 R 446462 CDS YP_003101949.1 256378289 8328441 5005205..5006023 1 NC_013093.1 hypothetical protein 5006023 8328441 Amir_4248 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101949.1 5005205 D 446462 CDS YP_003101950.1 256378290 8328442 5006027..5007454 1 NC_013093.1 hypothetical protein 5007454 8328442 Amir_4249 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101950.1 5006027 D 446462 CDS YP_003101951.1 256378291 8328443 5007451..5009280 1 NC_013093.1 KEGG: bvi:Bcep1808_7108 ATPase; hypothetical protein 5009280 8328443 Amir_4250 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101951.1 5007451 D 446462 CDS YP_003101952.1 256378292 8328444 complement(5009351..5010694) 1 NC_013093.1 KEGG: mxa:MXAN_1171 oxidoreductase, short chain dehydrogenase/reductase family; oxidoreductase, short chain dehydrogenase/reductase family 5010694 8328444 Amir_4251 Actinosynnema mirum DSM 43827 oxidoreductase, short chain dehydrogenase/reductase family YP_003101952.1 5009351 R 446462 CDS YP_003101953.1 256378293 8328449 complement(5011299..5011709) 1 NC_013093.1 KEGG: sme:SMa0312 hypothetical protein; hypothetical protein 5011709 8328449 Amir_4252 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101953.1 5011299 R 446462 CDS YP_003101954.1 256378294 8328450 5011825..5012421 1 NC_013093.1 KEGG: scl:sce1386 galactoside O-acetyltransferase; galactoside O-acetyltransferase 5012421 8328450 Amir_4253 Actinosynnema mirum DSM 43827 galactoside O-acetyltransferase YP_003101954.1 5011825 D 446462 CDS YP_003101955.1 256378295 8328451 complement(5012444..5012707) 1 NC_013093.1 hypothetical protein 5012707 8328451 Amir_4254 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101955.1 5012444 R 446462 CDS YP_003101956.1 256378296 8328452 5012927..5014051 1 NC_013093.1 KEGG: excinuclease ABC C subunit domain protein; hypothetical protein 5014051 8328452 Amir_4255 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101956.1 5012927 D 446462 CDS YP_003101957.1 256378297 8328453 complement(5014057..5015076) 1 NC_013093.1 KEGG: rce:RC1_0609 D-alanine--D-alanine ligase B; D-alanine--D-alanine ligase 5015076 8328453 Amir_4256 Actinosynnema mirum DSM 43827 D-alanine--D-alanine ligase YP_003101957.1 5014057 R 446462 CDS YP_003101958.1 256378298 8328454 complement(5015080..5016369) 1 NC_013093.1 KEGG: predicted protein; hypothetical protein 5016369 8328454 Amir_4257 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101958.1 5015080 R 446462 CDS YP_003101959.1 256378299 8328455 complement(5016432..5017286) 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: zgc:113054; O-methyltransferase 5017286 8328455 Amir_4258 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003101959.1 5016432 R 446462 CDS YP_003101960.1 256378300 8328456 complement(5017283..5018503) 1 NC_013093.1 PFAM: 3-dehydroquinate synthase; KEGG: hypothetical protein; K01735 3- dehydroquinate synthase; 3-dehydroquinate synthase 5018503 8328456 Amir_4259 Actinosynnema mirum DSM 43827 3-dehydroquinate synthase YP_003101960.1 5017283 R 446462 CDS YP_003101961.1 256378301 8328457 complement(5018912..5019565) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 5019565 8328457 Amir_4260 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101961.1 5018912 R 446462 CDS YP_003101962.1 256378302 8328458 complement(5019589..5020878) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 5020878 8328458 Amir_4261 Actinosynnema mirum DSM 43827 histidine kinase YP_003101962.1 5019589 R 446462 CDS YP_003101963.1 256378303 8328459 complement(5020949..5023036) 1 NC_013093.1 PFAM: beta-lactamase; KEGG: swi:Swit_4612 beta-lactamase; beta-lactamase 5023036 8328459 Amir_4262 Actinosynnema mirum DSM 43827 beta-lactamase YP_003101963.1 5020949 R 446462 CDS YP_003101964.1 256378304 8328460 complement(5023373..5023705) 1 NC_013093.1 hypothetical protein 5023705 8328460 Amir_4263 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101964.1 5023373 R 446462 CDS YP_003101965.1 256378305 8328461 complement(5023702..5023800) 1 NC_013093.1 hypothetical protein 5023800 8328461 Amir_4264 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101965.1 5023702 R 446462 CDS YP_003101966.1 256378306 8328462 complement(5024123..5027659) 1 NC_013093.1 KEGG: bur:Bcep18194_B1559 hypothetical protein; hypothetical protein 5027659 8328462 Amir_4265 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101966.1 5024123 R 446462 CDS YP_003101967.1 256378307 8328463 complement(5027774..5030689) 1 NC_013093.1 KEGG: bur:Bcep18194_B1559 hypothetical protein; hypothetical protein 5030689 8328463 Amir_4266 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101967.1 5027774 R 446462 CDS YP_003101968.1 256378308 8328464 5030801..5031103 1 NC_013093.1 hypothetical protein 5031103 8328464 Amir_4267 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101968.1 5030801 D 446462 CDS YP_003101969.1 256378309 8328465 complement(5031123..5031530) 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: scl:sce5646 hypothetical protein; endoribonuclease L-PSP 5031530 8328465 Amir_4268 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003101969.1 5031123 R 446462 CDS YP_003101970.1 256378310 8328466 5031607..5032377 1 NC_013093.1 PFAM: protein of unknown function DUF124; KEGG: protein of unknown function DUF124; hypothetical protein 5032377 8328466 Amir_4269 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101970.1 5031607 D 446462 CDS YP_003101971.1 256378311 8328468 5033153..5033401 1 NC_013093.1 hypothetical protein 5033401 8328468 Amir_4271 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101971.1 5033153 D 446462 CDS YP_003101972.1 256378312 8328469 complement(5033537..5034286) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: swi:Swit_1445 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 5034286 8328469 Amir_4272 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003101972.1 5033537 R 446462 CDS YP_003101973.1 256378313 8328470 5034388..5034825 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rpb:RPB_1659 MarR family transcriptional regulator; MarR family transcriptional regulator 5034825 8328470 Amir_4273 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003101973.1 5034388 D 446462 CDS YP_003101974.1 256378314 8328471 5034949..5035632 1 NC_013093.1 KEGG: aba:Acid345_2268 hypothetical protein; hypothetical protein 5035632 8328471 Amir_4274 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101974.1 5034949 D 446462 CDS YP_003101975.1 256378315 8328472 complement(5035654..5038338) 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; LuxR family transcriptional regulator 5038338 8328472 Amir_4275 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003101975.1 5035654 R 446462 CDS YP_003101976.1 256378316 8328473 complement(5038430..5038561) 1 NC_013093.1 hypothetical protein 5038561 8328473 Amir_4276 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101976.1 5038430 R 446462 CDS YP_003101977.1 256378317 8328474 complement(5038992..5040149) 1 NC_013093.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pfl:PFL_0942 Oye family NADH-dependent flavin oxidoreductase; NADH:flavin oxidoreductase/NADH oxidase 5040149 8328474 Amir_4277 Actinosynnema mirum DSM 43827 NADH:flavin oxidoreductase/NADH oxidase YP_003101977.1 5038992 R 446462 CDS YP_003101978.1 256378318 8328475 5040280..5040879 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bbt:BBta_0873 TetR family transcriptional regulator; TetR family transcriptional regulator 5040879 8328475 Amir_4278 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003101978.1 5040280 D 446462 CDS YP_003101979.1 256378319 8328476 5040990..5041976 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce5395 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 5041976 8328476 Amir_4279 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003101979.1 5040990 D 446462 CDS YP_003101980.1 256378320 8328477 5041976..5043313 1 NC_013093.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: scl:sce5396 hypothetical protein; MATE efflux family protein 5043313 8328477 Amir_4280 Actinosynnema mirum DSM 43827 MATE efflux family protein YP_003101980.1 5041976 D 446462 CDS YP_003101981.1 256378321 8328478 complement(5043300..5044298) 1 NC_013093.1 KEGG: spe:Spro_1475 hydrolase family protein; hydrolase family protein 5044298 8328478 Amir_4281 Actinosynnema mirum DSM 43827 hydrolase family protein YP_003101981.1 5043300 R 446462 CDS YP_003101982.1 256378322 8328479 5044329..5045093 1 NC_013093.1 KEGG: bha:BH0194 repressor in the phenylacetic acid catabolic pathway; PaaX family transcriptional regulator 5045093 8328479 Amir_4282 Actinosynnema mirum DSM 43827 PaaX family transcriptional regulator YP_003101982.1 5044329 D 446462 CDS YP_003101983.1 256378323 8328480 complement(5045098..5045472) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bsu:BSU19120 hypothetical protein; ArsR family transcriptional regulator 5045472 8328480 Amir_4283 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003101983.1 5045098 R 446462 CDS YP_003101984.1 256378324 8328481 5045568..5047532 1 NC_013093.1 TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: afe:Lferr_0209 heavy metal translocating P- type ATPase; heavy metal translocating P-type ATPase 5047532 8328481 Amir_4284 Actinosynnema mirum DSM 43827 heavy metal translocating P-type ATPase YP_003101984.1 5045568 D 446462 CDS YP_003101985.1 256378325 8328482 5047658..5048992 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: smd:Smed_5611 major facilitator superfamily MFS_1; major facilitator superfamily protein 5048992 8328482 Amir_4285 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003101985.1 5047658 D 446462 CDS YP_003101986.1 256378326 8328483 complement(5049053..5049409) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: dvm:DvMF_1207 transcriptional regulator, ArsR family; ArsR family transcriptional regulator 5049409 8328483 Amir_4286 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003101986.1 5049053 R 446462 CDS YP_003101987.1 256378327 8328484 5049602..5050474 1 NC_013093.1 PFAM: iron permease FTR1; KEGG: pde:Pden_1733 iron permease FTR1; iron permease FTR1 5050474 8328484 Amir_4287 Actinosynnema mirum DSM 43827 iron permease FTR1 YP_003101987.1 5049602 D 446462 CDS YP_003101988.1 256378328 8328485 5050471..5051592 1 NC_013093.1 KEGG: nmn:NMCC_0036 hypothetical protein; hypothetical protein 5051592 8328485 Amir_4288 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101988.1 5050471 D 446462 CDS YP_003101989.1 256378329 8328486 5051589..5052914 1 NC_013093.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: bur:Bcep18194_A3951 Dyp-type peroxidase; Dyp-type peroxidase family 5052914 8328486 Amir_4289 Actinosynnema mirum DSM 43827 Dyp-type peroxidase family YP_003101989.1 5051589 D 446462 CDS YP_003101990.1 256378330 8328487 5053009..5053407 1 NC_013093.1 PFAM: Penicillinase repressor; KEGG: mxa:MXAN_7319 transcriptional regulator; CopY family transcriptional regulator 5053407 8328487 Amir_4290 Actinosynnema mirum DSM 43827 CopY family transcriptional regulator YP_003101990.1 5053009 D 446462 CDS YP_003101991.1 256378331 8328488 complement(5053448..5053948) 1 NC_013093.1 PFAM: protein of unknown function DUF1470; KEGG: bbr:BB0827 hypothetical protein; hypothetical protein 5053948 8328488 Amir_4291 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101991.1 5053448 R 446462 CDS YP_003101992.1 256378332 8328489 5054017..5055105 1 NC_013093.1 PFAM: Epoxide hydrolase domain protein; alpha/beta hydrolase fold; KEGG: bpy:Bphyt_5343 epoxide hydrolase domain protein; Epoxide hydrolase domain-containing protein 5055105 8328489 Amir_4292 Actinosynnema mirum DSM 43827 Epoxide hydrolase domain-containing protein YP_003101992.1 5054017 D 446462 CDS YP_003101993.1 256378333 8328490 complement(5055248..5056090) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pde:Pden_3525 ABC transporter; ABC transporter 5056090 8328490 Amir_4293 Actinosynnema mirum DSM 43827 ABC transporter YP_003101993.1 5055248 R 446462 CDS YP_003101994.1 256378334 8328491 complement(5056087..5057181) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: oan:Oant_2825 transport system permease protein; transport system permease 5057181 8328491 Amir_4294 Actinosynnema mirum DSM 43827 transport system permease YP_003101994.1 5056087 R 446462 CDS YP_003101995.1 256378335 8328492 complement(5057178..5058221) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: oan:Oant_2826 transport system permease protein; transport system permease 5058221 8328492 Amir_4295 Actinosynnema mirum DSM 43827 transport system permease YP_003101995.1 5057178 R 446462 CDS YP_003101996.1 256378336 8328493 complement(5058218..5059258) 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: pde:Pden_3522 periplasmic binding protein; periplasmic binding protein 5059258 8328493 Amir_4296 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003101996.1 5058218 R 446462 CDS YP_003101997.1 256378337 8328494 complement(5059695..5060801) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap 5060801 8328494 Amir_4297 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003101997.1 5059695 R 446462 CDS YP_003101998.1 256378338 8328495 complement(5061303..5062049) 1 NC_013093.1 KEGG: PT repeat family protein; hypothetical protein 5062049 8328495 Amir_4298 Actinosynnema mirum DSM 43827 hypothetical protein YP_003101998.1 5061303 R 446462 CDS YP_003101999.1 256378339 8328496 complement(5062194..5062943) 1 NC_013093.1 PFAM: ANTAR domain protein; KEGG: afw:Anae109_3912 multi-sensor signal transduction histidine kinase; ANTAR domain-containing protein with unknown sensor 5062943 8328496 Amir_4299 Actinosynnema mirum DSM 43827 ANTAR domain-containing protein with unknown sensor YP_003101999.1 5062194 R 446462 CDS YP_003102000.1 256378340 8328497 complement(5063119..5063847) 1 NC_013093.1 PFAM: Orn/Lys/Arg decarboxylase domain protein; Orn/Lys/Arg decarboxylase major region; KEGG: bha:BH2640 lysine decarboxylase; Orn/Lys/Arg decarboxylase domain-containing protein 5063847 8328497 Amir_4300 Actinosynnema mirum DSM 43827 Orn/Lys/Arg decarboxylase domain-containing protein YP_003102000.1 5063119 R 446462 CDS YP_003102001.1 256378341 8328498 complement(5063942..5064727) 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: azo:azo0656 LuxR family transcriptional regulator; LuxR family transcriptional regulator 5064727 8328498 Amir_4301 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102001.1 5063942 R 446462 CDS YP_003102002.1 256378342 8328499 complement(5065271..5066116) 1 NC_013093.1 PFAM: protein of unknown function DUF88; KEGG: dal:Dalk_1950 cold-shock DNA-binding domain protein; hypothetical protein 5066116 8328499 Amir_4302 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102002.1 5065271 R 446462 CDS YP_003102003.1 256378343 8328500 complement(5066410..5067138) 1 NC_013093.1 KEGG: nmu:Nmul_A2202 hypothetical protein; hypothetical protein 5067138 8328500 Amir_4303 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102003.1 5066410 R 446462 CDS YP_003102004.1 256378344 8328502 5067812..5068663 1 NC_013093.1 hypothetical protein 5068663 8328502 Amir_4305 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102004.1 5067812 D 446462 CDS YP_003102005.1 256378345 8328503 5068751..5069569 1 NC_013093.1 PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: scl:sce6912 thiosulfate sulfurtransferase; rhodanese domain-containing protein 5069569 8328503 Amir_4306 Actinosynnema mirum DSM 43827 rhodanese domain-containing protein YP_003102005.1 5068751 D 446462 CDS YP_003102006.1 256378346 8328504 5069566..5070909 1 NC_013093.1 PFAM: FAD linked oxidase domain protein; KEGG: scl:sce0752 glycolate oxidase; FAD linked oxidase domain-containing protein 5070909 8328504 Amir_4307 Actinosynnema mirum DSM 43827 FAD linked oxidase domain-containing protein YP_003102006.1 5069566 D 446462 CDS YP_003102007.1 256378347 8328505 5070938..5071699 1 NC_013093.1 KEGG: reh:H16_A2809 peptidase, S33 family; hypothetical protein 5071699 8328505 Amir_4308 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102007.1 5070938 D 446462 CDS YP_003102008.1 256378348 8328506 5071806..5074973 1 NC_013093.1 KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 5074973 8328506 Amir_4309 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102008.1 5071806 D 446462 CDS YP_003102009.1 256378349 8328507 complement(5075204..5075815) 1 NC_013093.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: flavoprotein oxidoreductase protein; flavin reductase domain-containing protein 5075815 8328507 Amir_4310 Actinosynnema mirum DSM 43827 flavin reductase domain-containing protein YP_003102009.1 5075204 R 446462 CDS YP_003102010.1 256378350 8328508 5076012..5076908 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rpi:Rpic_3636 transcriptional regulator, LysR family; LysR family transcriptional regulator 5076908 8328508 Amir_4311 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102010.1 5076012 D 446462 CDS YP_003102011.1 256378351 8328509 5077001..5078215 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: ssuD; alkanesulfonate monooxygenase protein; Alkanesulfonate monooxygenase 5078215 8328509 Amir_4312 Actinosynnema mirum DSM 43827 Alkanesulfonate monooxygenase YP_003102011.1 5077001 D 446462 CDS YP_003102012.1 256378352 8328510 5078230..5079423 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: bja:bll6452 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase type 2 domain-containing protein 5079423 8328510 Amir_4313 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003102012.1 5078230 D 446462 CDS YP_003102013.1 256378353 8328511 5079547..5079645 1 NC_013093.1 hypothetical protein 5079645 8328511 Amir_4314 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102013.1 5079547 D 446462 CDS YP_003102014.1 256378354 8328512 complement(5079706..5080404) 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; KEGG: scl:sce8831 ThiJ/PfpI family protein; ThiJ/PfpI domain-containing protein 5080404 8328512 Amir_4315 Actinosynnema mirum DSM 43827 ThiJ/PfpI domain-containing protein YP_003102014.1 5079706 R 446462 CDS YP_003102015.1 256378355 8328513 5080501..5081463 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6302 AraC family transcriptional regulator; AraC family transcriptional regulator 5081463 8328513 Amir_4316 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102015.1 5080501 D 446462 CDS YP_003102016.1 256378356 8328514 5081610..5082605 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_A3489 transcriptional regulator, AraC- family; AraC family transcriptional regulator 5082605 8328514 Amir_4317 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102016.1 5081610 D 446462 CDS YP_003102017.1 256378357 8328515 complement(5082678..5082968) 1 NC_013093.1 hypothetical protein 5082968 8328515 Amir_4318 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102017.1 5082678 R 446462 CDS YP_003102018.1 256378358 8328517 5085486..5087150 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: bbt:BBta_4832 ABC transporter (substrate binding protein); family 5 extracellular solute-binding protein 5087150 8328517 Amir_4320 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003102018.1 5085486 D 446462 CDS YP_003102019.1 256378359 8328518 5087147..5088118 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_4833 ABC transporter (permease protein); ABC transporter inner membrane protein 5088118 8328518 Amir_4321 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102019.1 5087147 D 446462 CDS YP_003102020.1 256378360 8328519 5088115..5088957 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_4834 ABC transporter (permease protein); ABC transporter inner membrane protein 5088957 8328519 Amir_4322 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102020.1 5088115 D 446462 CDS YP_003102021.1 256378361 8328520 5088936..5090579 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: peptide ABC transporter; ABC transporter 5090579 8328520 Amir_4323 Actinosynnema mirum DSM 43827 ABC transporter YP_003102021.1 5088936 D 446462 CDS YP_003102022.1 256378362 8328521 5090720..5092030 1 NC_013093.1 TIGRFAM: hypothetical protein; PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein 5092030 8328521 Amir_4324 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102022.1 5090720 D 446462 CDS YP_003102023.1 256378363 8328522 complement(5092080..5092490) 1 NC_013093.1 hypothetical protein 5092490 8328522 Amir_4325 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102023.1 5092080 R 446462 CDS YP_003102024.1 256378364 8328523 complement(5092777..5093160) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 5093160 8328523 Amir_4326 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102024.1 5092777 R 446462 CDS YP_003102025.1 256378365 8328524 complement(5093325..5093834) 1 NC_013093.1 hypothetical protein 5093834 8328524 Amir_4327 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102025.1 5093325 R 446462 CDS YP_003102026.1 256378366 8328525 complement(5094141..5094656) 1 NC_013093.1 KEGG: scl:sce0948 hypothetical protein; hypothetical protein 5094656 8328525 Amir_4328 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102026.1 5094141 R 446462 CDS YP_003102027.1 256378367 8328526 5094764..5095636 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: bra:BRADO4150 hypothetical protein; XRE family transcriptional regulator 5095636 8328526 Amir_4329 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102027.1 5094764 D 446462 CDS YP_003102028.1 256378368 8328527 5095709..5096992 1 NC_013093.1 KEGG: scl:sce8953 hypothetical protein; hypothetical protein 5096992 8328527 Amir_4330 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102028.1 5095709 D 446462 CDS YP_003102029.1 256378369 8328528 complement(5097047..5098291) 1 NC_013093.1 PFAM: glycoside hydrolase family 46; Ricin B lectin; SMART: Ricin B lectin; KEGG: bsu:BSU26890 chitosanase; glycoside hydrolase family protein 5098291 8328528 Amir_4331 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003102029.1 5097047 R 446462 CDS YP_003102030.1 256378370 8328529 5098585..5099019 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dvm:DvMF_2540 response regulator receiver protein; response regulator receiver protein 5099019 8328529 Amir_4332 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003102030.1 5098585 D 446462 CDS YP_003102031.1 256378371 8328530 5099183..5100976 1 NC_013093.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: oxidoreductase protein; K07077; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 5100976 8328530 Amir_4333 Actinosynnema mirum DSM 43827 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein YP_003102031.1 5099183 D 446462 CDS YP_003102032.1 256378372 8328532 complement(5102067..5102588) 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: aha:AHA_0491 AsnC family transcriptional regulator; AsnC family transcriptional regulator 5102588 8328532 Amir_4335 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003102032.1 5102067 R 446462 CDS YP_003102033.1 256378373 8328533 complement(5102644..5102913) 1 NC_013093.1 hypothetical protein 5102913 8328533 Amir_4336 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102033.1 5102644 R 446462 CDS YP_003102034.1 256378374 8328534 complement(5103039..5103926) 1 NC_013093.1 PFAM: integral membrane protein TerC; KEGG: integral membrane protein TerC; integral membrane protein TerC 5103926 8328534 Amir_4337 Actinosynnema mirum DSM 43827 integral membrane protein TerC YP_003102034.1 5103039 R 446462 CDS YP_003102035.1 256378375 8328535 complement(5104555..5105250) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: nha:Nham_3206 TetR family transcriptional regulator; TetR family transcriptional regulator 5105250 8328535 Amir_4338 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102035.1 5104555 R 446462 CDS YP_003102036.1 256378376 8328536 complement(5105234..5106538) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: sme:SMc02891 oxidoreductase transmembrane protein; FAD-binding monooxygenase 5106538 8328536 Amir_4339 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102036.1 5105234 R 446462 CDS YP_003102037.1 256378377 8328537 complement(5106593..5107792) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_3850 major facilitator transporter; major facilitator superfamily protein 5107792 8328537 Amir_4340 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102037.1 5106593 R 446462 CDS YP_003102038.1 256378378 8328538 complement(5107865..5108902) 1 NC_013093.1 KEGG: met:M446_2055 methyl-accepting chemotaxis sensory transducer; hypothetical protein 5108902 8328538 Amir_4341 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102038.1 5107865 R 446462 CDS YP_003102039.1 256378379 8328539 5109178..5110428 1 NC_013093.1 PFAM: sodium/hydrogen exchanger; KEGG: mxa:MXAN_0260 cation transporter/universal stress family protein; sodium/hydrogen exchanger 5110428 8328539 Amir_4342 Actinosynnema mirum DSM 43827 sodium/hydrogen exchanger YP_003102039.1 5109178 D 446462 CDS YP_003102040.1 256378380 8328540 complement(5110473..5110838) 1 NC_013093.1 KEGG: ade:Adeh_2705 response regulator receiver; hypothetical protein 5110838 8328540 Amir_4343 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102040.1 5110473 R 446462 CDS YP_003102041.1 256378381 8328541 complement(5110835..5112637) 1 NC_013093.1 hypothetical protein 5112637 8328541 Amir_4344 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102041.1 5110835 R 446462 CDS YP_003102042.1 256378382 8328542 complement(5112684..5113904) 1 NC_013093.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bcb:BCB4264_A0206 drug resistance transporter, Bcr/CflA family; Bcr/CflA subfamily drug resistance transporter 5113904 8328542 Amir_4345 Actinosynnema mirum DSM 43827 Bcr/CflA subfamily drug resistance transporter YP_003102042.1 5112684 R 446462 CDS YP_003102043.1 256378383 8328543 5113941..5114384 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: dac:Daci_5402 transcriptional regulator, TrmB; MarR family transcriptional regulator 5114384 8328543 Amir_4346 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003102043.1 5113941 D 446462 CDS YP_003102044.1 256378384 8328544 complement(5114391..5117417) 1 NC_013093.1 SMART: ATPase AAA; KEGG: scl:sce3623 hypothetical protein; signal transduction protein with Nacht domain 5117417 8328544 Amir_4347 Actinosynnema mirum DSM 43827 signal transduction protein with Nacht domain YP_003102044.1 5114391 R 446462 CDS YP_003102045.1 256378385 8328545 complement(5117476..5117958) 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: rru:Rru_A3685 AsnC family transcriptional regulator; AsnC family transcriptional regulator 5117958 8328545 Amir_4348 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003102045.1 5117476 R 446462 CDS YP_003102046.1 256378386 8328546 5118087..5118695 1 NC_013093.1 PFAM: protein of unknown function DUF161; KEGG: rpi:Rpic_4668 protein of unknown function DUF161; hypothetical protein 5118695 8328546 Amir_4349 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102046.1 5118087 D 446462 CDS YP_003102047.1 256378387 8328547 complement(5118772..5121582) 1 NC_013093.1 KEGG: nha:Nham_0826 hypothetical protein; hypothetical protein 5121582 8328547 Amir_4350 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102047.1 5118772 R 446462 CDS YP_003102048.1 256378388 8328548 5121845..5122534 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bxe:Bxe_A0699 two component transcriptional regulator; winged helix family two component transcriptional regulator 5122534 8328548 Amir_4351 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003102048.1 5121845 D 446462 CDS YP_003102049.1 256378389 8328549 5122531..5123862 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ade:Adeh_2943 histidine kinase; histidine kinase 5123862 8328549 Amir_4352 Actinosynnema mirum DSM 43827 histidine kinase YP_003102049.1 5122531 D 446462 CDS YP_003102050.1 256378390 8328550 complement(5123917..5125440) 1 NC_013093.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: rsh:Rsph17029_1579 histidine ammonia-lyase; Histidine ammonia-lyase 5125440 8328550 Amir_4353 Actinosynnema mirum DSM 43827 Histidine ammonia-lyase YP_003102050.1 5123917 R 446462 CDS YP_003102051.1 256378391 8328551 5125504..5127054 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: RCJMB04_10a6, FOXRED2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 5127054 8328551 Amir_4354 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003102051.1 5125504 D 446462 CDS YP_003102052.1 256378392 8328552 5127047..5128474 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: vei:Veis_4674 acyl-CoA synthetase; AMP-dependent synthetase and ligase 5128474 8328552 Amir_4355 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102052.1 5127047 D 446462 CDS YP_003102053.1 256378393 8328553 complement(5128550..5138752) 1 NC_013093.1 PFAM: KR domain protein; beta-ketoacyl synthase; acyl transferase; erythronolide synthase docking; short- chain dehydrogenase/reductase SDR; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase; KR domain-containing protein 5138752 8328553 Amir_4356 Actinosynnema mirum DSM 43827 KR domain-containing protein YP_003102053.1 5128550 R 446462 CDS YP_003102054.1 256378394 8328554 complement(5138804..5141272) 1 NC_013093.1 PFAM: beta-ketoacyl synthase; KEGG: eca:ECA0603 type I polyketide synthase; beta-ketoacyl synthase 5141272 8328554 Amir_4357 Actinosynnema mirum DSM 43827 beta-ketoacyl synthase YP_003102054.1 5138804 R 446462 CDS YP_003102055.1 256378395 8328555 complement(5141269..5142612) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: scl:sce4847 hypothetical protein; FAD-binding monooxygenase 5142612 8328555 Amir_4358 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102055.1 5141269 R 446462 CDS YP_003102056.1 256378396 8328556 complement(5142609..5152235) 1 NC_013093.1 PFAM: acyl transferase; KR domain protein; beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 5152235 8328556 Amir_4359 Actinosynnema mirum DSM 43827 acyl transferase YP_003102056.1 5142609 R 446462 CDS YP_003102057.1 256378397 8328557 complement(5152509..5153840) 1 NC_013093.1 PFAM: glycosyl transferase family 28; KEGG: ses:SARI_00205 hypothetical protein; glycosyl transferase family protein 5153840 8328557 Amir_4360 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003102057.1 5152509 R 446462 CDS YP_003102058.1 256378398 8328558 complement(5153954..5155189) 1 NC_013093.1 PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; KEGG: ses:SARI_00205 hypothetical protein; hypothetical protein 5155189 8328558 Amir_4361 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102058.1 5153954 R 446462 CDS YP_003102059.1 256378399 8328559 5155490..5156230 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: glo:Glov_3377 methyltransferase type 11; type 11 methyltransferase 5156230 8328559 Amir_4362 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003102059.1 5155490 D 446462 CDS YP_003102060.1 256378400 8328560 complement(5156329..5156628) 1 NC_013093.1 hypothetical protein 5156628 8328560 Amir_4363 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102060.1 5156329 R 446462 CDS YP_003102061.1 256378401 8328563 5157612..5158619 1 NC_013093.1 KEGG: afw:Anae109_1986 extracellular HAF; hypothetical protein 5158619 8328563 Amir_4366 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102061.1 5157612 D 446462 CDS YP_003102062.1 256378402 8328564 complement(5158663..5159640) 1 NC_013093.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: rpt:Rpal_2151 2-nitropropane dioxygenase NPD; 2-nitropropane dioxygenase NPD 5159640 8328564 Amir_4367 Actinosynnema mirum DSM 43827 2-nitropropane dioxygenase NPD YP_003102062.1 5158663 R 446462 CDS YP_003102063.1 256378403 8328565 complement(5159653..5160795) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: IVD; IVD (ISOVALERYL-COA-DEHYDROGENASE); K00253 isovaleryl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 5160795 8328565 Amir_4368 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003102063.1 5159653 R 446462 CDS YP_003102064.1 256378404 8328566 complement(5160829..5161449) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rpd:RPD_4359 regulatory protein, TetR; TetR family transcriptional regulator 5161449 8328566 Amir_4369 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102064.1 5160829 R 446462 CDS YP_003102065.1 256378405 8328567 complement(5161497..5163302) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce8696 long-chain fatty-acid-- CoA ligase; AMP-dependent synthetase and ligase 5163302 8328567 Amir_4370 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102065.1 5161497 R 446462 CDS YP_003102066.1 256378406 8328568 5163548..5164756 1 NC_013093.1 KEGG: mxa:MXAN_6988 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase 5164756 8328568 Amir_4371 Actinosynnema mirum DSM 43827 acetyl-CoA acetyltransferase YP_003102066.1 5163548 D 446462 CDS YP_003102067.1 256378407 8328569 5164804..5166969 1 NC_013093.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: mxa:MXAN_6987 fatty oxidation complex, alpha subunit; 3-hydroxyacyl-CoA dehydrogenase 5166969 8328569 Amir_4372 Actinosynnema mirum DSM 43827 3-hydroxyacyl-CoA dehydrogenase YP_003102067.1 5164804 D 446462 CDS YP_003102068.1 256378408 8328570 complement(5166988..5167677) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: sme:SMa2387 transcriptional regulator, TetR family; TetR family transcriptional regulator 5167677 8328570 Amir_4373 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102068.1 5166988 R 446462 CDS YP_003102069.1 256378409 8328571 5167841..5169070 1 NC_013093.1 KEGG: scl:sce5500 hypothetical protein; hypothetical protein 5169070 8328571 Amir_4374 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102069.1 5167841 D 446462 CDS YP_003102070.1 256378410 8328572 5169108..5170355 1 NC_013093.1 KEGG: scl:sce5500 hypothetical protein; hypothetical protein 5170355 8328572 Amir_4375 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102070.1 5169108 D 446462 CDS YP_003102071.1 256378411 8328573 5170367..5172715 1 NC_013093.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mxa:MXAN_1752 isoquinoline 1-oxidoreductase, beta subunit; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 5172715 8328573 Amir_4376 Actinosynnema mirum DSM 43827 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_003102071.1 5170367 D 446462 CDS YP_003102072.1 256378412 8328574 5172860..5173363 1 NC_013093.1 PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: mxa:MXAN_1751 isoquinoline 1-oxidoreductase, alpha subunit; (2Fe-2S)-binding domain-containing protein 5173363 8328574 Amir_4377 Actinosynnema mirum DSM 43827 (2Fe-2S)-binding domain-containing protein YP_003102072.1 5172860 D 446462 CDS YP_003102073.1 256378413 8328575 complement(5173421..5174149) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: atc:AGR_pAT_269 hypothetical protein; MerR family transcriptional regulator 5174149 8328575 Amir_4378 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003102073.1 5173421 R 446462 CDS YP_003102074.1 256378414 8328576 5175087..5176760 1 NC_013093.1 PFAM: polyprenyl synthetase; KEGG: hne:HNE_0678 polyprenyl synthetase; polyprenyl synthetase 5176760 8328576 Amir_4379 Actinosynnema mirum DSM 43827 polyprenyl synthetase YP_003102074.1 5175087 D 446462 CDS YP_003102075.1 256378415 8328577 5176760..5177743 1 NC_013093.1 PFAM: UbiA prenyltransferase; KEGG: bbt:BBta_6422 bacteriochlorophyll/chlorophyll a synthase; UbiA prenyltransferase 5177743 8328577 Amir_4380 Actinosynnema mirum DSM 43827 UbiA prenyltransferase YP_003102075.1 5176760 D 446462 CDS YP_003102076.1 256378416 8328578 5177850..5179103 1 NC_013093.1 PFAM: monooxygenase FAD-binding; glucose-inhibited division protein A; FAD dependent oxidoreductase; KEGG: bmn:BMA10247_A1734 monooxygenase; FAD-binding monooxygenase 5179103 8328578 Amir_4381 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102076.1 5177850 D 446462 CDS YP_003102077.1 256378417 8328579 complement(5179112..5180104) 1 NC_013093.1 PFAM: O-methyltransferase; KEGG: sus:Acid_5654 hydroxyneurosporene-O- methyltransferase; O-methyltransferase 5180104 8328579 Amir_4382 Actinosynnema mirum DSM 43827 O-methyltransferase YP_003102077.1 5179112 R 446462 CDS YP_003102078.1 256378418 8328580 5180272..5181117 1 NC_013093.1 PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: pla:Plav_2004 taurine dioxygenase; taurine dioxygenase 5181117 8328580 Amir_4383 Actinosynnema mirum DSM 43827 taurine dioxygenase YP_003102078.1 5180272 D 446462 CDS YP_003102079.1 256378419 8328581 complement(5181213..5182415) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: bca:BCE_2654 cytochrome P450; cytochrome P450 5182415 8328581 Amir_4384 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003102079.1 5181213 R 446462 CDS YP_003102080.1 256378420 8328582 complement(5182451..5184133) 1 NC_013093.1 PFAM: Prenyltransferase/squalene oxidase; KEGG: afw:Anae109_4079 squalene-hopene cyclase; Prenyltransferase/squalene oxidase 5184133 8328582 Amir_4385 Actinosynnema mirum DSM 43827 Prenyltransferase/squalene oxidase YP_003102080.1 5182451 R 446462 CDS YP_003102081.1 256378421 8328583 complement(5184380..5185381) 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: scl:sce8915 histidinol-phosphate transaminase; class I and II aminotransferase 5185381 8328583 Amir_4386 Actinosynnema mirum DSM 43827 class I and II aminotransferase YP_003102081.1 5184380 R 446462 CDS YP_003102082.1 256378422 8328584 5185962..5187251 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: floR; florfenicol/chloramphenicol resistance transporter protein; major facilitator superfamily protein 5187251 8328584 Amir_4387 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102082.1 5185962 D 446462 CDS YP_003102083.1 256378423 8328585 5187352..5187795 1 NC_013093.1 KEGG: dal:Dalk_2807 hypothetical protein; hypothetical protein 5187795 8328585 Amir_4388 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102083.1 5187352 D 446462 CDS YP_003102084.1 256378424 8328586 complement(5187921..5189153) 1 NC_013093.1 KEGG: mxa:MXAN_1195 hypothetical protein; hypothetical protein 5189153 8328586 Amir_4389 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102084.1 5187921 R 446462 CDS YP_003102085.1 256378425 8328587 complement(5189293..5190555) 1 NC_013093.1 KEGG: bcz:BCZK1172 signal peptidase I; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24 and S26 domain protein; SMART: LamG domain protein jellyroll fold domain protein; peptidase S26B, signal peptidase 5190555 8328587 Amir_4390 Actinosynnema mirum DSM 43827 peptidase S26B, signal peptidase YP_003102085.1 5189293 R 446462 CDS YP_003102086.1 256378426 8328588 complement(5190552..5191169) 1 NC_013093.1 KEGG: MUC1.3; hypothetical protein, likely cell wall localized and GPI-anchored mucin like; hypothetical protein 5191169 8328588 Amir_4391 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102086.1 5190552 R 446462 CDS YP_003102087.1 256378427 8328589 5191394..5191936 1 NC_013093.1 PFAM: SCP-like extracellular; KEGG: noc:Noc_1373 hypothetical protein; SCP-like extracellular 5191936 8328589 Amir_4392 Actinosynnema mirum DSM 43827 SCP-like extracellular YP_003102087.1 5191394 D 446462 CDS YP_003102088.1 256378428 8328590 complement(5192055..5192795) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6740 AraC family transcriptional regulator; AraC family transcriptional regulator 5192795 8328590 Amir_4393 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102088.1 5192055 R 446462 CDS YP_003102089.1 256378429 8328591 5192871..5193431 1 NC_013093.1 hypothetical protein 5193431 8328591 Amir_4394 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102089.1 5192871 D 446462 CDS YP_003102090.1 256378430 8328592 complement(5193446..5194036) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_4360 regulatory protein TetR; TetR family transcriptional regulator 5194036 8328592 Amir_4395 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102090.1 5193446 R 446462 CDS YP_003102091.1 256378431 8328593 complement(5194084..5194773) 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; KEGG: reu:Reut_A0026 ThiJ/PfpI; ThiJ/PfpI domain-containing protein 5194773 8328593 Amir_4396 Actinosynnema mirum DSM 43827 ThiJ/PfpI domain-containing protein YP_003102091.1 5194084 R 446462 CDS YP_003102092.1 256378432 8328594 complement(5194910..5195308) 1 NC_013093.1 hypothetical protein 5195308 8328594 Amir_4397 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102092.1 5194910 R 446462 CDS YP_003102093.1 256378433 8328595 complement(5195346..5196095) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: esa:ESA_01962 hypothetical protein; short-chain dehydrogenase/reductase SDR 5196095 8328595 Amir_4398 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102093.1 5195346 R 446462 CDS YP_003102094.1 256378434 8328596 5196187..5196789 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: afw:Anae109_3254 TetR family transcriptional regulator; TetR family transcriptional regulator 5196789 8328596 Amir_4399 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102094.1 5196187 D 446462 CDS YP_003102095.1 256378435 8328597 5196863..5197774 1 NC_013093.1 PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; KEGG: har:HEAR1617 transcriptional regulator (CadR); MerR family transcriptional regulator 5197774 8328597 Amir_4400 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003102095.1 5196863 D 446462 CDS YP_003102096.1 256378436 8328599 complement(5198601..5199272) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: mes:Meso_2933 transcriptional regulator, GntR family; GntR family transcriptional regulator 5199272 8328599 Amir_4402 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003102096.1 5198601 R 446462 CDS YP_003102097.1 256378437 8328600 5199382..5199906 1 NC_013093.1 PFAM: PEBP family protein; KEGG: PEBP family protein; PEBP family protein 5199906 8328600 Amir_4403 Actinosynnema mirum DSM 43827 PEBP family protein YP_003102097.1 5199382 D 446462 CDS YP_003102098.1 256378438 8328601 complement(5200156..5203194) 1 NC_013093.1 KEGG: bur:Bcep18194_B1559 hypothetical protein; hypothetical protein 5203194 8328601 Amir_4404 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102098.1 5200156 R 446462 CDS YP_003102099.1 256378439 8328602 5203586..5204890 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_A3378 transcriptional regulator, AraC- family; AraC family transcriptional regulator 5204890 8328602 Amir_4405 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102099.1 5203586 D 446462 CDS YP_003102100.1 256378440 8328603 5204955..5205131 1 NC_013093.1 hypothetical protein 5205131 8328603 Amir_4406 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102100.1 5204955 D 446462 CDS YP_003102101.1 256378441 8328604 5205155..5205538 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist; anti-sigma-factor antagonist 5205538 8328604 Amir_4407 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003102101.1 5205155 D 446462 CDS YP_003102102.1 256378442 8328605 5205764..5206945 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: cti:RALTA_A0583 glycosyl transferase, group 1; group 1 glycosyl transferase 5206945 8328605 Amir_4408 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003102102.1 5205764 D 446462 CDS YP_003102103.1 256378443 8328606 complement(5206949..5207920) 1 NC_013093.1 KEGG: lpc:LPC_2297 hypothetical protein; Mn2+dependent serine/threonine protein kinase 5207920 8328606 Amir_4409 Actinosynnema mirum DSM 43827 Mn2+dependent serine/threonine protein kinase YP_003102103.1 5206949 R 446462 CDS YP_003102104.1 256378444 8328607 complement(5207956..5208474) 1 NC_013093.1 KEGG: nar:Saro_3607 short-chain dehydrogenase/reductase SDR; hypothetical protein 5208474 8328607 Amir_4410 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102104.1 5207956 R 446462 CDS YP_003102105.1 256378445 8328609 5210003..5210428 1 NC_013093.1 hypothetical protein 5210428 8328609 Amir_4412 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102105.1 5210003 D 446462 CDS YP_003102106.1 256378446 8328610 5210512..5210955 1 NC_013093.1 PFAM: ferric-uptake regulator; KEGG: afw:Anae109_2251 ferric uptake regulator family protein; Fur family ferric uptake regulator 5210955 8328610 Amir_4413 Actinosynnema mirum DSM 43827 Fur family ferric uptake regulator YP_003102106.1 5210512 D 446462 CDS YP_003102107.1 256378447 8328611 complement(5211027..5211188) 1 NC_013093.1 TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; 50S ribosomal protein L32 5211188 8328611 Amir_4414 Actinosynnema mirum DSM 43827 50S ribosomal protein L32 YP_003102107.1 5211027 R 446462 CDS YP_003102108.1 256378448 8328612 complement(5211188..5211439) 1 NC_013093.1 TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: bha:BH3780 50S ribosomal protein L31 type B; 50S ribosomal protein L31 5211439 8328612 Amir_4415 Actinosynnema mirum DSM 43827 50S ribosomal protein L31 YP_003102108.1 5211188 R 446462 CDS YP_003102109.1 256378449 8328613 complement(5211436..5212527) 1 NC_013093.1 PFAM: cobalamin synthesis CobW domain protein; KEGG: bxe:Bxe_A4503 cobalamin synthesis protein/P47K; cobalamin synthesis CobW domain-containing protein 5212527 8328613 Amir_4416 Actinosynnema mirum DSM 43827 cobalamin synthesis CobW domain-containing protein YP_003102109.1 5211436 R 446462 CDS YP_003102110.1 256378450 8328614 complement(5212657..5214129) 1 NC_013093.1 PFAM: Catalase domain protein; KEGG: ppd:Ppro_1932 catalase; Catalase 5214129 8328614 Amir_4417 Actinosynnema mirum DSM 43827 Catalase YP_003102110.1 5212657 R 446462 CDS YP_003102111.1 256378451 8328615 5214277..5214951 1 NC_013093.1 PFAM: glutamine amidotransferase class-I; KEGG: rpi:Rpic_0998 glutamine amidotransferase class-I; glutamine amidotransferase class-I 5214951 8328615 Amir_4418 Actinosynnema mirum DSM 43827 glutamine amidotransferase class-I YP_003102111.1 5214277 D 446462 CDS YP_003102112.1 256378452 8328616 5214948..5215637 1 NC_013093.1 PFAM: MOSC domain containing protein; KEGG: rsh:Rsph17029_0572 MOSC domain-containing protein; MOSC domain containing protein 5215637 8328616 Amir_4419 Actinosynnema mirum DSM 43827 MOSC domain containing protein YP_003102112.1 5214948 D 446462 CDS YP_003102113.1 256378453 8328617 5215696..5216241 1 NC_013093.1 TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: oca:OCAR_6549 MIP; peroxidase-like protein 5216241 8328617 Amir_4420 Actinosynnema mirum DSM 43827 peroxidase-like protein YP_003102113.1 5215696 D 446462 CDS YP_003102114.1 256378454 8328618 5216389..5216982 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: oca:OCAR_6548 transcriptional regulator, MarR family; MarR family transcriptional regulator 5216982 8328618 Amir_4421 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003102114.1 5216389 D 446462 CDS YP_003102115.1 256378455 8328619 complement(5216993..5217976) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_B0937 transcriptional regulator, AraC- family; AraC family transcriptional regulator 5217976 8328619 Amir_4422 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102115.1 5216993 R 446462 CDS YP_003102116.1 256378456 8328620 5218113..5219024 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mlo:mlr3236 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 5219024 8328620 Amir_4423 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003102116.1 5218113 D 446462 CDS YP_003102117.1 256378457 8328621 complement(5219040..5220053) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: cti:RALTA_B0761 transcriptional regulator, AraC family; AraC family transcriptional regulator 5220053 8328621 Amir_4424 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102117.1 5219040 R 446462 CDS YP_003102118.1 256378458 8328622 5220181..5221089 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mlo:mlr3236 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 5221089 8328622 Amir_4425 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003102118.1 5220181 D 446462 CDS YP_003102119.1 256378459 8328623 complement(5221124..5222218) 1 NC_013093.1 PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: cti:RALTA_A2171 serine/threonine protein phosphatase, P2C family; protein serine/threonine phosphatase 5222218 8328623 Amir_4426 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003102119.1 5221124 R 446462 CDS YP_003102120.1 256378460 8328625 complement(5223000..5223938) 1 NC_013093.1 PFAM: NmrA family protein; KEGG: mxa:MXAN_7053 NmrA-like family protein; NmrA family protein 5223938 8328625 Amir_4428 Actinosynnema mirum DSM 43827 NmrA family protein YP_003102120.1 5223000 R 446462 CDS YP_003102121.1 256378461 8328626 5224106..5224996 1 NC_013093.1 PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: scl:sce1423 LysR family transcriptional regulator; LysR family transcriptional regulator 5224996 8328626 Amir_4429 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102121.1 5224106 D 446462 CDS YP_003102122.1 256378462 8328627 5225142..5225579 1 NC_013093.1 PFAM: stress responsive alpha-beta barrel domain protein; stress responsive alpha-beta barrel domain-containing protein 5225579 8328627 Amir_4430 Actinosynnema mirum DSM 43827 stress responsive alpha-beta barrel domain-containing protein YP_003102122.1 5225142 D 446462 CDS YP_003102123.1 256378463 8328628 5225576..5226634 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: ccs:CCNA_02209 quinone oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 5226634 8328628 Amir_4431 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003102123.1 5225576 D 446462 CDS YP_003102124.1 256378464 8328629 5226631..5227197 1 NC_013093.1 hypothetical protein 5227197 8328629 Amir_4432 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102124.1 5226631 D 446462 CDS YP_003102125.1 256378465 8328630 complement(5227194..5227841) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 5227841 8328630 Amir_4433 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102125.1 5227194 R 446462 CDS YP_003102126.1 256378466 8328631 complement(5227838..5228947) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: gdi:GDI1194 two-component system sensor protein; histidine kinase 5228947 8328631 Amir_4434 Actinosynnema mirum DSM 43827 histidine kinase YP_003102126.1 5227838 R 446462 CDS YP_003102127.1 256378467 8328632 5229068..5229256 1 NC_013093.1 KEGG: bcr:BCAH187_A2835 HIT family hydrolase; HIT family hydrolase 5229256 8328632 Amir_4435 Actinosynnema mirum DSM 43827 HIT family hydrolase YP_003102127.1 5229068 D 446462 CDS YP_003102128.1 256378468 8328633 5229934..5231376 1 NC_013093.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: reh:H16_A0856 L-amino-acid oxidase; amine oxidase 5231376 8328633 Amir_4436 Actinosynnema mirum DSM 43827 amine oxidase YP_003102128.1 5229934 D 446462 CDS YP_003102129.1 256378469 8328634 complement(5231562..5232446) 1 NC_013093.1 PFAM: ABC transporter; KEGG: rpb:RPB_3405 hypothetical protein; ABC transporter 5232446 8328634 Amir_4437 Actinosynnema mirum DSM 43827 ABC transporter YP_003102129.1 5231562 R 446462 CDS YP_003102130.1 256378470 8328635 complement(5232443..5233183) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: plu:plu2673 iron transport system ATP-binding protein YfeB; ABC transporter 5233183 8328635 Amir_4438 Actinosynnema mirum DSM 43827 ABC transporter YP_003102130.1 5232443 R 446462 CDS YP_003102131.1 256378471 8328636 complement(5233180..5234094) 1 NC_013093.1 PFAM: periplasmic solute binding protein; KEGG: rsq:Rsph17025_0249 periplasmic solute binding protein; periplasmic solute binding protein 5234094 8328636 Amir_4439 Actinosynnema mirum DSM 43827 periplasmic solute binding protein YP_003102131.1 5233180 R 446462 CDS YP_003102132.1 256378472 8328637 complement(5234581..5240904) 1 NC_013093.1 TIGRFAM: thioester reductase domain protein; PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; Male sterility domain; KR domain protein; acyl transferase; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA0602 type I polyketide synthase; thioester reductase domain-containing protein 5240904 8328637 Amir_4440 Actinosynnema mirum DSM 43827 thioester reductase domain-containing protein YP_003102132.1 5234581 R 446462 CDS YP_003102133.1 256378473 8328638 complement(5240932..5249832) 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 5249832 8328638 Amir_4441 Actinosynnema mirum DSM 43827 acyl transferase YP_003102133.1 5240932 R 446462 CDS YP_003102134.1 256378474 8328639 complement(5249837..5260849) 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; NAD- dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 5260849 8328639 Amir_4442 Actinosynnema mirum DSM 43827 acyl transferase YP_003102134.1 5249837 R 446462 CDS YP_003102135.1 256378475 8328640 complement(5260871..5269414) 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: eca:ECA0602 type I polyketide synthase; acyl transferase 5269414 8328640 Amir_4443 Actinosynnema mirum DSM 43827 acyl transferase YP_003102135.1 5260871 R 446462 CDS YP_003102136.1 256378476 8328641 complement(5269440..5270756) 1 NC_013093.1 KEGG: bur:Bcep18194_C6844 regulator of polyketide synthase expression; PucR family transcriptional regulator 5270756 8328641 Amir_4444 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003102136.1 5269440 R 446462 CDS YP_003102137.1 256378477 8328642 complement(5270766..5272331) 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: ppu:PP_2782 pyridoxalphosphate dependent aminotransferase, class III; class III aminotransferase 5272331 8328642 Amir_4445 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003102137.1 5270766 R 446462 CDS YP_003102138.1 256378478 8328643 5272505..5272870 1 NC_013093.1 KEGG: pap:PSPA7_2619 hypothetical protein; hypothetical protein 5272870 8328643 Amir_4446 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102138.1 5272505 D 446462 CDS YP_003102139.1 256378479 8328644 complement(5272944..5274140) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: pol:Bpro_2060 acyl-CoA dehydrogenase, C- terminal type2; acyl-CoA dehydrogenase type 2 domain-containing protein 5274140 8328644 Amir_4447 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003102139.1 5272944 R 446462 CDS YP_003102140.1 256378480 8328645 5274353..5274850 1 NC_013093.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: nar:Saro_1462 flavin reductase-like, FMN- binding; flavin reductase domain-containing protein 5274850 8328645 Amir_4448 Actinosynnema mirum DSM 43827 flavin reductase domain-containing protein YP_003102140.1 5274353 D 446462 CDS YP_003102141.1 256378481 8328646 complement(5274895..5275356) 1 NC_013093.1 hypothetical protein 5275356 8328646 Amir_4449 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102141.1 5274895 R 446462 CDS YP_003102142.1 256378482 8328647 complement(5275360..5276322) 1 NC_013093.1 PFAM: ribonucleotide reductase; KEGG: bba:Bd1983 ribonucleotide-diphosphate reductase small chain; ribonucleotide reductase 5276322 8328647 Amir_4450 Actinosynnema mirum DSM 43827 ribonucleotide reductase YP_003102142.1 5275360 R 446462 CDS YP_003102143.1 256378483 8328648 complement(5276414..5277214) 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: ade:Adeh_3289 SARP family transcriptional regulator; SARP family transcriptional regulator 5277214 8328648 Amir_4451 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003102143.1 5276414 R 446462 CDS YP_003102144.1 256378484 8328649 complement(5277705..5278862) 1 NC_013093.1 SMART: regulatory protein LuxR; KEGG: nha:Nham_1032 LuxR family transcriptional regulator; LuxR family transcriptional regulator 5278862 8328649 Amir_4452 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102144.1 5277705 R 446462 CDS YP_003102145.1 256378485 8328650 complement(5279469..5280800) 1 NC_013093.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: reh:H16_A0856 L-amino-acid oxidase; amine oxidase 5280800 8328650 Amir_4453 Actinosynnema mirum DSM 43827 amine oxidase YP_003102145.1 5279469 R 446462 CDS YP_003102146.1 256378486 8328651 complement(5281007..5281852) 1 NC_013093.1 PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: rpd:RPD_2341 NmrA-like; NmrA family protein 5281852 8328651 Amir_4454 Actinosynnema mirum DSM 43827 NmrA family protein YP_003102146.1 5281007 R 446462 CDS YP_003102147.1 256378487 8328652 5281933..5282892 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mno:Mnod_1588 transcriptional regulator, AraC family; AraC family transcriptional regulator 5282892 8328652 Amir_4455 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102147.1 5281933 D 446462 CDS YP_003102148.1 256378488 8328653 complement(5282988..5283743) 1 NC_013093.1 PFAM: protein of unknown function DUF81; KEGG: sfu:Sfum_1521 protein of unknown function DUF81; hypothetical protein 5283743 8328653 Amir_4456 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102148.1 5282988 R 446462 CDS YP_003102149.1 256378489 8328654 5284250..5284561 1 NC_013093.1 hypothetical protein 5284561 8328654 Amir_4457 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102149.1 5284250 D 446462 CDS YP_003102150.1 256378490 8328655 complement(5284569..5285387) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; XRE family transcriptional regulator 5285387 8328655 Amir_4458 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102150.1 5284569 R 446462 CDS YP_003102151.1 256378491 8328656 complement(5285392..5286303) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: xcv:XCV0256 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 5286303 8328656 Amir_4459 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102151.1 5285392 R 446462 CDS YP_003102152.1 256378492 8328657 complement(5286406..5286870) 1 NC_013093.1 KEGG: bbt:BBta_5025 hypothetical protein; hypothetical protein 5286870 8328657 Amir_4460 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102152.1 5286406 R 446462 CDS YP_003102153.1 256378493 8328658 complement(5286867..5287418) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bcz:BCZK4730 TetR family transcriptional regulator; TetR family transcriptional regulator 5287418 8328658 Amir_4461 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102153.1 5286867 R 446462 CDS YP_003102154.1 256378494 8328659 complement(5287411..5288244) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: hypothetical protein; alpha/beta hydrolase fold protein 5288244 8328659 Amir_4462 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003102154.1 5287411 R 446462 CDS YP_003102155.1 256378495 8328660 5288447..5289106 1 NC_013093.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: afw:Anae109_2808 NADP oxidoreductase coenzyme F420-dependent; NADP oxidoreductase coenzyme F420-dependent 5289106 8328660 Amir_4463 Actinosynnema mirum DSM 43827 NADP oxidoreductase coenzyme F420-dependent YP_003102155.1 5288447 D 446462 CDS YP_003102156.1 256378496 8328661 complement(5289116..5289682) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: atc:AGR_pAT_729 hypothetical protein; TetR family transcriptional regulator 5289682 8328661 Amir_4464 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102156.1 5289116 R 446462 CDS YP_003102157.1 256378497 8328662 complement(5290060..5292159) 1 NC_013093.1 PFAM: oxidoreductase FAD-binding domain protein; pyridoxamine 5'-phosphate oxidase-related FMN-binding; ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: scl:sce7711 hypothetical protein; oxidoreductase FAD-binding domain-containing protein 5292159 8328662 Amir_4465 Actinosynnema mirum DSM 43827 oxidoreductase FAD-binding domain-containing protein YP_003102157.1 5290060 R 446462 CDS YP_003102158.1 256378498 8328663 5292246..5292860 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: pla:Plav_1079 TetR family transcriptional regulator; TetR family transcriptional regulator 5292860 8328663 Amir_4466 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102158.1 5292246 D 446462 CDS YP_003102159.1 256378499 8328664 5293004..5293729 1 NC_013093.1 KEGG: scl:sce9100 hypothetical protein; hypothetical protein 5293729 8328664 Amir_4467 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102159.1 5293004 D 446462 CDS YP_003102160.1 256378500 8328665 complement(5293797..5295590) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: afw:Anae109_0968 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 5295590 8328665 Amir_4468 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102160.1 5293797 R 446462 CDS YP_003102161.1 256378501 8328666 5295830..5296171 1 NC_013093.1 KEGG: similar to hyphally regulated cell wall protein HYR1p; hyphally regulated cell wall protein HYR1p-like protein 5296171 8328666 Amir_4469 Actinosynnema mirum DSM 43827 hyphally regulated cell wall protein HYR1p-like protein YP_003102161.1 5295830 D 446462 CDS YP_003102162.1 256378502 8328667 5296310..5296441 1 NC_013093.1 hypothetical protein 5296441 8328667 Amir_4470 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102162.1 5296310 D 446462 CDS YP_003102163.1 256378503 8328668 complement(5296524..5296820) 1 NC_013093.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: jan:Jann_1295 antibiotic biosynthesis monooxygenase; Antibiotic biosynthesis monooxygenase 5296820 8328668 Amir_4471 Actinosynnema mirum DSM 43827 Antibiotic biosynthesis monooxygenase YP_003102163.1 5296524 R 446462 CDS YP_003102164.1 256378504 8328669 complement(5296902..5297519) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: xau:Xaut_2611 TetR family transcriptional regulator; TetR family transcriptional regulator 5297519 8328669 Amir_4472 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102164.1 5296902 R 446462 CDS YP_003102165.1 256378505 8328670 5297612..5298289 1 NC_013093.1 PFAM: nitroreductase; KEGG: pla:Plav_2473 nitroreductase; nitroreductase 5298289 8328670 Amir_4473 Actinosynnema mirum DSM 43827 nitroreductase YP_003102165.1 5297612 D 446462 CDS YP_003102166.1 256378506 8328671 complement(5298302..5298985) 1 NC_013093.1 hypothetical protein 5298985 8328671 Amir_4474 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102166.1 5298302 R 446462 CDS YP_003102167.1 256378507 8328672 complement(5299045..5300217) 1 NC_013093.1 KEGG: rle:RL4432 hypothetical protein; hypothetical protein 5300217 8328672 Amir_4475 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102167.1 5299045 R 446462 CDS YP_003102168.1 256378508 8328674 complement(5301065..5302810) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: pap:PSPA7_0145 serine/threonine protein kinase PpkA; serine/threonine protein kinase 5302810 8328674 Amir_4477 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003102168.1 5301065 R 446462 CDS YP_003102169.1 256378509 8328676 5304179..5305330 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 5305330 8328676 Amir_4479 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003102169.1 5304179 D 446462 CDS YP_003102170.1 256378510 8328677 5305327..5306661 1 NC_013093.1 KEGG: rle:pRL120266 hypothetical protein; hypothetical protein 5306661 8328677 Amir_4480 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102170.1 5305327 D 446462 CDS YP_003102171.1 256378511 8328678 5306658..5307833 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: cvi:CV_1398 hypothetical protein; major facilitator superfamily protein 5307833 8328678 Amir_4481 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102171.1 5306658 D 446462 CDS YP_003102172.1 256378512 8328679 5307830..5308987 1 NC_013093.1 PFAM: ROK family protein; KEGG: scl:sce7667 ROK family transcriptional regulator; ROK family protein 5308987 8328679 Amir_4482 Actinosynnema mirum DSM 43827 ROK family protein YP_003102172.1 5307830 D 446462 CDS YP_003102173.1 256378513 8328680 complement(5309081..5309464) 1 NC_013093.1 KEGG: mpo:Mpop_1521 short-chain dehydrogenase/reductase SDR; hypothetical protein 5309464 8328680 Amir_4483 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102173.1 5309081 R 446462 CDS YP_003102174.1 256378514 8328681 complement(5309496..5309918) 1 NC_013093.1 KEGG: bja:blr2505 hypothetical protein; hypothetical protein 5309918 8328681 Amir_4484 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102174.1 5309496 R 446462 CDS YP_003102175.1 256378515 8328682 complement(5310025..5311170) 1 NC_013093.1 KEGG: ade:Adeh_2548 L-lysine 2,3-aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein 5311170 8328682 Amir_4485 Actinosynnema mirum DSM 43827 lysine 2,3-aminomutase YodO family protein YP_003102175.1 5310025 R 446462 CDS YP_003102176.1 256378516 8328683 complement(5311185..5316260) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: scl:sce8257 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 5316260 8328683 Amir_4486 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102176.1 5311185 R 446462 CDS YP_003102177.1 256378517 8328684 5316799..5317956 1 NC_013093.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: afw:Anae109_4239 monooxygenase FAD-binding; FAD-binding monooxygenase 5317956 8328684 Amir_4487 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102177.1 5316799 D 446462 CDS YP_003102178.1 256378518 8328685 5317992..5319260 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pen:PSEEN0980 L-ornithine 5-/L-lysine 6- monooxygenase; L-lysine 6-monooxygenase (NADPH) 5319260 8328685 Amir_4488 Actinosynnema mirum DSM 43827 L-lysine 6-monooxygenase (NADPH) YP_003102178.1 5317992 D 446462 CDS YP_003102179.1 256378519 8328686 5319270..5319926 1 NC_013093.1 PFAM: Negative transcriptional regulator; KEGG: pmy:Pmen_0131 FMN-binding negative transcriptional regulator; FMN-binding negative transcriptional regulator 5319926 8328686 Amir_4489 Actinosynnema mirum DSM 43827 FMN-binding negative transcriptional regulator YP_003102179.1 5319270 D 446462 CDS YP_003102180.1 256378520 8328687 5319923..5321431 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: hch:HCH_03445 non-ribosomal peptide synthetase modules and related protein; amino acid adenylation domain-containing protein 5321431 8328687 Amir_4490 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102180.1 5319923 D 446462 CDS YP_003102181.1 256378521 8328688 complement(5321478..5322749) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_2815 major facilitator transporter; major facilitator superfamily protein 5322749 8328688 Amir_4491 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102181.1 5321478 R 446462 CDS YP_003102182.1 256378522 8328689 complement(5322746..5324695) 1 NC_013093.1 KEGG: rpe:RPE_0078 carbamoyltransferase; carbamoyl transferase NodU family-like protein 5324695 8328689 Amir_4492 Actinosynnema mirum DSM 43827 carbamoyl transferase NodU family-like protein YP_003102182.1 5322746 R 446462 CDS YP_003102183.1 256378523 8328690 complement(5324692..5325459) 1 NC_013093.1 PFAM: Thioesterase; KEGG: mxa:MXAN_4290 thioesterase; Thioesterase 5325459 8328690 Amir_4493 Actinosynnema mirum DSM 43827 Thioesterase YP_003102183.1 5324692 R 446462 CDS YP_003102184.1 256378524 8328691 complement(5325437..5326720) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: scl:sce7867 cytochrome P450 CYP124E1; cytochrome P450 5326720 8328691 Amir_4494 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003102184.1 5325437 R 446462 CDS YP_003102185.1 256378525 8328692 complement(5326717..5328396) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: mxa:MXAN_4601 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein 5328396 8328692 Amir_4495 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102185.1 5326717 R 446462 CDS YP_003102186.1 256378526 8328693 complement(5328398..5329090) 1 NC_013093.1 KEGG: bja:blr5743 hypothetical protein; hypothetical protein 5329090 8328693 Amir_4496 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102186.1 5328398 R 446462 CDS YP_003102187.1 256378527 8328694 complement(5329090..5330094) 1 NC_013093.1 PFAM: GHMP kinase; KEGG: bvi:Bcep1808_5165 GHMP kinase; GHMP kinase 5330094 8328694 Amir_4497 Actinosynnema mirum DSM 43827 GHMP kinase YP_003102187.1 5329090 R 446462 CDS YP_003102188.1 256378528 8328695 complement(5330091..5335769) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3618 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 5335769 8328695 Amir_4498 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102188.1 5330091 R 446462 CDS YP_003102189.1 256378529 8328696 complement(5335766..5336812) 1 NC_013093.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: bpd:BURPS668_2111 L-allo-threonine aldolase; Threonine aldolase 5336812 8328696 Amir_4499 Actinosynnema mirum DSM 43827 Threonine aldolase YP_003102189.1 5335766 R 446462 CDS YP_003102190.1 256378530 8328697 complement(5336809..5339079) 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: bps:BPSL1715 argininosuccinate lyase; cysteine synthase 5339079 8328697 Amir_4500 Actinosynnema mirum DSM 43827 cysteine synthase YP_003102190.1 5336809 R 446462 CDS YP_003102191.1 256378531 8328698 complement(5339076..5340659) 1 NC_013093.1 PFAM: fumarate lyase; KEGG: rsq:Rsph17025_3642 hypothetical protein; fumarate lyase 5340659 8328698 Amir_4501 Actinosynnema mirum DSM 43827 fumarate lyase YP_003102191.1 5339076 R 446462 CDS YP_003102192.1 256378532 8328699 complement(5340656..5340871) 1 NC_013093.1 PFAM: MbtH domain protein; KEGG: rpc:RPC_1861 MbtH-like protein; MbtH domain-containing protein 5340871 8328699 Amir_4502 Actinosynnema mirum DSM 43827 MbtH domain-containing protein YP_003102192.1 5340656 R 446462 CDS YP_003102193.1 256378533 8328700 complement(5340885..5342804) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: aav:Aave_3731 amino acid adenylation domain; amino acid adenylation domain-containing protein 5342804 8328700 Amir_4503 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102193.1 5340885 R 446462 CDS YP_003102194.1 256378534 8328701 5343145..5343639 1 NC_013093.1 hypothetical protein 5343639 8328701 Amir_4504 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102194.1 5343145 D 446462 CDS YP_003102195.1 256378535 8328702 5343682..5344965 1 NC_013093.1 PFAM: condensation domain protein; KEGG: mxa:MXAN_4415 non-ribosomal peptide synthetase/polyketide synthase; condensation domain-containing protein 5344965 8328702 Amir_4505 Actinosynnema mirum DSM 43827 condensation domain-containing protein YP_003102195.1 5343682 D 446462 CDS YP_003102196.1 256378536 8328703 5344962..5346830 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: mxa:MXAN_3779 non-ribosomal peptide synthetase/polyketide synthase; amino acid adenylation domain-containing protein 5346830 8328703 Amir_4506 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102196.1 5344962 D 446462 CDS YP_003102197.1 256378537 8328704 5346994..5347242 1 NC_013093.1 KEGG: mlo:mlr3218 hypothetical protein; hypothetical protein 5347242 8328704 Amir_4507 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102197.1 5346994 D 446462 CDS YP_003102198.1 256378538 8328705 5347572..5349653 1 NC_013093.1 KEGG: bcz:BCZK2539 UvrD/Rep helicase family protein; superfamily I DNA and RNA helicase-like protein 5349653 8328705 Amir_4508 Actinosynnema mirum DSM 43827 superfamily I DNA and RNA helicase-like protein YP_003102198.1 5347572 D 446462 CDS YP_003102199.1 256378539 8328706 complement(5349713..5351884) 1 NC_013093.1 PFAM: MMPL domain protein; KEGG: bsu:BSU05430 hypothetical protein; MMPL domain-containing protein 5351884 8328706 Amir_4509 Actinosynnema mirum DSM 43827 MMPL domain-containing protein YP_003102199.1 5349713 R 446462 CDS YP_003102200.1 256378540 8328707 5352063..5353289 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 5353289 8328707 Amir_4510 Actinosynnema mirum DSM 43827 histidine kinase YP_003102200.1 5352063 D 446462 CDS YP_003102201.1 256378541 8328708 5353286..5353966 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 5353966 8328708 Amir_4511 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102201.1 5353286 D 446462 CDS YP_003102202.1 256378542 8328709 5354019..5354672 1 NC_013093.1 PFAM: VanZ family protein; KEGG: bha:BH2294 hypothetical protein; VanZ family protein 5354672 8328709 Amir_4512 Actinosynnema mirum DSM 43827 VanZ family protein YP_003102202.1 5354019 D 446462 CDS YP_003102203.1 256378543 8328710 complement(5354581..5355729) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sfu:Sfum_2006 integral membrane sensor signal transduction histidine kinase; histidine kinase 5355729 8328710 Amir_4513 Actinosynnema mirum DSM 43827 histidine kinase YP_003102203.1 5354581 R 446462 CDS YP_003102204.1 256378544 8328711 complement(5355722..5356390) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sus:Acid_5477 two component transcriptional regulator; winged helix family two component transcriptional regulator 5356390 8328711 Amir_4514 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003102204.1 5355722 R 446462 CDS YP_003102205.1 256378545 8328712 complement(5356496..5357632) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: mxa:MXAN_5466 peptidase, S1E (streptogrisin A) subfamily; peptidase S1 and S6 chymotrypsin/Hap 5357632 8328712 Amir_4515 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003102205.1 5356496 R 446462 CDS YP_003102206.1 256378546 8328713 5357935..5358984 1 NC_013093.1 PFAM: cellulose-binding family II; lipolytic protein G-D-S-L family; SMART: cellulose-binding family II; KEGG: scl:sce7021 endoglucanase; cellulose-binding family protein 5358984 8328713 Amir_4516 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003102206.1 5357935 D 446462 CDS YP_003102207.1 256378547 8328714 5359238..5359597 1 NC_013093.1 hypothetical protein 5359597 8328714 Amir_4517 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102207.1 5359238 D 446462 CDS YP_003102208.1 256378548 8328715 5359594..5360172 1 NC_013093.1 hypothetical protein 5360172 8328715 Amir_4518 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102208.1 5359594 D 446462 CDS YP_003102209.1 256378549 8328716 5360186..5361508 1 NC_013093.1 KEGG: GG22683 gene product from transcript GG22683- RA; hypothetical protein 5361508 8328716 Amir_4519 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102209.1 5360186 D 446462 CDS YP_003102210.1 256378550 8328717 5361505..5362284 1 NC_013093.1 KEGG: rru:Rru_A3404 TrkA domain-containing protein; hypothetical protein 5362284 8328717 Amir_4520 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102210.1 5361505 D 446462 CDS YP_003102211.1 256378551 8328718 complement(5362294..5363166) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: bsu:BSU03260 hypothetical protein; alpha/beta hydrolase fold protein 5363166 8328718 Amir_4521 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003102211.1 5362294 R 446462 CDS YP_003102212.1 256378552 8328719 5363436..5364356 1 NC_013093.1 KEGG: bsu:BSU02240 extracellular metalloprotease; extracellular metalloprotease 5364356 8328719 Amir_4522 Actinosynnema mirum DSM 43827 extracellular metalloprotease YP_003102212.1 5363436 D 446462 CDS YP_003102213.1 256378553 8328720 5364413..5364832 1 NC_013093.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: sit:TM1040_1898 twin-arginine translocation pathway signal; hypothetical protein 5364832 8328720 Amir_4523 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102213.1 5364413 D 446462 CDS YP_003102214.1 256378554 8328721 complement(5364843..5365229) 1 NC_013093.1 hypothetical protein 5365229 8328721 Amir_4524 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102214.1 5364843 R 446462 CDS YP_003102215.1 256378555 8328723 complement(5368097..5368786) 1 NC_013093.1 KEGG: Gpr125; G protein-coupled receptor 125; K08462 G protein-coupled receptor 125; hypothetical protein 5368786 8328723 Amir_4526 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102215.1 5368097 R 446462 CDS YP_003102216.1 256378556 8328724 complement(5368783..5369091) 1 NC_013093.1 hypothetical protein 5369091 8328724 Amir_4527 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102216.1 5368783 R 446462 CDS YP_003102217.1 256378557 8328725 complement(5369197..5370045) 1 NC_013093.1 hypothetical protein 5370045 8328725 Amir_4528 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102217.1 5369197 R 446462 CDS YP_003102218.1 256378558 8328726 complement(5370211..5370645) 1 NC_013093.1 hypothetical protein 5370645 8328726 Amir_4529 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102218.1 5370211 R 446462 CDS YP_003102219.1 256378559 8328727 5370867..5371301 1 NC_013093.1 hypothetical protein 5371301 8328727 Amir_4530 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102219.1 5370867 D 446462 CDS YP_003102220.1 256378560 8328728 5371621..5372274 1 NC_013093.1 KEGG: rso:RS03147 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; PAS fold-4 domain protein; SMART: PAS domain containing protein; regulatory protein LuxR; LuxR family transcriptional regulator 5372274 8328728 Amir_4531 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102220.1 5371621 D 446462 CDS YP_003102221.1 256378561 8328729 5372300..5373301 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce5395 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 5373301 8328729 Amir_4532 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003102221.1 5372300 D 446462 CDS YP_003102222.1 256378562 8328730 complement(5373348..5374430) 1 NC_013093.1 hypothetical protein 5374430 8328730 Amir_4533 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102222.1 5373348 R 446462 CDS YP_003102223.1 256378563 8328731 complement(5374427..5375422) 1 NC_013093.1 PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: hne:HNE_0812 oxidoreductase, NAD-binding; oxidoreductase domain-containing protein 5375422 8328731 Amir_4534 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003102223.1 5374427 R 446462 CDS YP_003102224.1 256378564 8328732 complement(5375412..5376671) 1 NC_013093.1 KEGG: scl:sce0971 hypothetical protein; hypothetical protein 5376671 8328732 Amir_4535 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102224.1 5375412 R 446462 CDS YP_003102225.1 256378565 8328733 complement(5376668..5376964) 1 NC_013093.1 KEGG: sfu:Sfum_3460 acyl carrier protein; hypothetical protein 5376964 8328733 Amir_4536 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102225.1 5376668 R 446462 CDS YP_003102226.1 256378566 8328734 complement(5376967..5378142) 1 NC_013093.1 PFAM: Radical SAM domain protein; KEGG: sfu:Sfum_2252 radical SAM domain protein; Radical SAM domain-containing protein 5378142 8328734 Amir_4537 Actinosynnema mirum DSM 43827 Radical SAM domain-containing protein YP_003102226.1 5376967 R 446462 CDS YP_003102227.1 256378567 8328735 5378419..5379774 1 NC_013093.1 PFAM: condensation domain protein; KEGG: bmn:BMA10247_A0621 peptide synthetase; condensation domain-containing protein 5379774 8328735 Amir_4538 Actinosynnema mirum DSM 43827 condensation domain-containing protein YP_003102227.1 5378419 D 446462 CDS YP_003102228.1 256378568 8328736 5379884..5380258 1 NC_013093.1 hypothetical protein 5380258 8328736 Amir_4539 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102228.1 5379884 D 446462 CDS YP_003102229.1 256378569 8328738 complement(5382947..5383078) 1 NC_013093.1 hypothetical protein 5383078 8328738 Amir_4541 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102229.1 5382947 R 446462 CDS YP_003102230.1 256378570 8328739 complement(5383248..5383601) 1 NC_013093.1 hypothetical protein 5383601 8328739 Amir_4542 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102230.1 5383248 R 446462 CDS YP_003102231.1 256378571 8328740 complement(5383588..5384067) 1 NC_013093.1 hypothetical protein 5384067 8328740 Amir_4543 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102231.1 5383588 R 446462 CDS YP_003102232.1 256378572 8328741 complement(5384030..5388496) 1 NC_013093.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; KEGG: rso:RS05482 rhs-related transmembrane protein; YD repeat-containing protein 5388496 8328741 Amir_4544 Actinosynnema mirum DSM 43827 YD repeat-containing protein YP_003102232.1 5384030 R 446462 CDS YP_003102233.1 256378573 8328743 5389116..5389673 1 NC_013093.1 hypothetical protein 5389673 8328743 Amir_4545 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102233.1 5389116 D 446462 CDS YP_003102234.1 256378574 8328744 5389670..5390743 1 NC_013093.1 PFAM: integrase family protein; KEGG: aeh:Mlg_1488 tyrosine recombinase XerD; integrase family protein 5390743 8328744 Amir_4546 Actinosynnema mirum DSM 43827 integrase family protein YP_003102234.1 5389670 D 446462 CDS YP_003102235.1 256378575 8328747 complement(5391796..5393868) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; FG-GAP repeat protein; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: acp:A2cp1_3748 hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap 5393868 8328747 Amir_4549 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003102235.1 5391796 R 446462 CDS YP_003102236.1 256378576 8328748 complement(5393882..5397004) 1 NC_013093.1 PFAM: protein of unknown function DUF312; KEGG: SNF2 superfamily protein; methyl-accepting chemotaxis sensory transducer 5397004 8328748 Amir_4550 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003102236.1 5393882 R 446462 CDS YP_003102237.1 256378577 8328749 5397643..5398521 1 NC_013093.1 hypothetical protein 5398521 8328749 Amir_4551 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102237.1 5397643 D 446462 CDS YP_003102238.1 256378578 8328751 5400713..5401804 1 NC_013093.1 KEGG: bxe:Bxe_A3516 transposase; transposase 5401804 8328751 Amir_4553 Actinosynnema mirum DSM 43827 transposase YP_003102238.1 5400713 D 446462 CDS YP_003102239.1 256378579 8328752 5402015..5403241 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: afw:Anae109_3372 hypothetical protein; XRE family transcriptional regulator 5403241 8328752 Amir_4554 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102239.1 5402015 D 446462 CDS YP_003102240.1 256378580 8328753 5403341..5404459 1 NC_013093.1 KEGG: mucin-associated surface protein (MASP); hypothetical protein 5404459 8328753 Amir_4555 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102240.1 5403341 D 446462 CDS YP_003102241.1 256378581 8328754 5405125..5406549 1 NC_013093.1 KEGG: mca:MCA2681 hypothetical protein; hypothetical protein 5406549 8328754 Amir_4556 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102241.1 5405125 D 446462 CDS YP_003102242.1 256378582 8328755 complement(5406539..5406775) 1 NC_013093.1 hypothetical protein 5406775 8328755 Amir_4557 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102242.1 5406539 R 446462 CDS YP_003102243.1 256378583 8328756 complement(5406911..5408107) 1 NC_013093.1 hypothetical protein 5408107 8328756 Amir_4558 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102243.1 5406911 R 446462 CDS YP_003102244.1 256378584 8328757 complement(5408444..5410147) 1 NC_013093.1 hypothetical protein 5410147 8328757 Amir_4559 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102244.1 5408444 R 446462 CDS YP_003102245.1 256378585 8328758 complement(5410429..5410551) 1 NC_013093.1 hypothetical protein 5410551 8328758 Amir_4560 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102245.1 5410429 R 446462 CDS YP_003102246.1 256378586 8328759 5411020..5411121 1 NC_013093.1 hypothetical protein 5411121 8328759 Amir_4561 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102246.1 5411020 D 446462 CDS YP_003102247.1 256378587 8328761 5411564..5412235 1 NC_013093.1 hypothetical protein 5412235 8328761 Amir_4563 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102247.1 5411564 D 446462 CDS YP_003102248.1 256378588 8328762 5412561..5412857 1 NC_013093.1 hypothetical protein 5412857 8328762 Amir_4564 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102248.1 5412561 D 446462 CDS YP_003102249.1 256378589 8328763 5413208..5413477 1 NC_013093.1 hypothetical protein 5413477 8328763 Amir_4565 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102249.1 5413208 D 446462 CDS YP_003102250.1 256378590 8328764 5413733..5414206 1 NC_013093.1 hypothetical protein 5414206 8328764 Amir_4566 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102250.1 5413733 D 446462 CDS YP_003102251.1 256378591 8328765 5414493..5415203 1 NC_013093.1 KEGG: hypothetical protein LOC743833; hypothetical protein 5415203 8328765 Amir_4567 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102251.1 5414493 D 446462 CDS YP_003102252.1 256378592 8328766 5415562..5416518 1 NC_013093.1 hypothetical protein 5416518 8328766 Amir_4568 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102252.1 5415562 D 446462 CDS YP_003102253.1 256378593 8328767 5416695..5416811 1 NC_013093.1 hypothetical protein 5416811 8328767 Amir_4569 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102253.1 5416695 D 446462 CDS YP_003102254.1 256378594 8328768 5416932..5418176 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: pin:Ping_0445 colicin uptake-like protein; XRE family transcriptional regulator 5418176 8328768 Amir_4570 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102254.1 5416932 D 446462 CDS YP_003102255.1 256378595 8328769 5418459..5419016 1 NC_013093.1 hypothetical protein 5419016 8328769 Amir_4571 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102255.1 5418459 D 446462 CDS YP_003102256.1 256378596 8328770 5419291..5419461 1 NC_013093.1 hypothetical protein 5419461 8328770 Amir_4572 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102256.1 5419291 D 446462 CDS YP_003102257.1 256378597 8328771 5419458..5420165 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pmy:Pmen_3998 phosphoglycolate phosphatase; HAD superfamily hydrolase 5420165 8328771 Amir_4573 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003102257.1 5419458 D 446462 CDS YP_003102258.1 256378598 8328772 5420633..5421262 1 NC_013093.1 hypothetical protein 5421262 8328772 Amir_4574 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102258.1 5420633 D 446462 CDS YP_003102259.1 256378599 8328773 5421259..5421969 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mno:Mnod_6944 phosphoglycolate phosphatase; HAD superfamily hydrolase 5421969 8328773 Amir_4575 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003102259.1 5421259 D 446462 CDS YP_003102260.1 256378600 8328774 5422067..5423161 1 NC_013093.1 KEGG: sus:Acid_3202 alpha/beta hydrolase fold; hypothetical protein 5423161 8328774 Amir_4576 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102260.1 5422067 D 446462 CDS YP_003102261.1 256378601 8328776 5424665..5425444 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 5425444 8328776 Amir_4578 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003102261.1 5424665 D 446462 CDS YP_003102262.1 256378602 8328778 5426251..5427441 1 NC_013093.1 KEGG: numb; numb homolog (Drosophila); K06057 numb; hypothetical protein 5427441 8328778 Amir_4580 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102262.1 5426251 D 446462 CDS YP_003102263.1 256378603 8328782 complement(5429735..5429995) 1 NC_013093.1 hypothetical protein 5429995 8328782 Amir_4584 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102263.1 5429735 R 446462 CDS YP_003102264.1 256378604 8328783 complement(5430003..5434247) 1 NC_013093.1 KEGG: scl:sce2557 secreted protein; hypothetical protein 5434247 8328783 Amir_4585 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102264.1 5430003 R 446462 CDS YP_003102265.1 256378605 8328784 complement(5434642..5435196) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: kpn:KPN_01751 acetyltransferase; GCN5-like N-acetyltransferase 5435196 8328784 Amir_4586 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003102265.1 5434642 R 446462 CDS YP_003102266.1 256378606 8328785 complement(5435237..5436142) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: pfo:Pfl01_3628 hypothetical protein; type 11 methyltransferase 5436142 8328785 Amir_4587 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003102266.1 5435237 R 446462 CDS YP_003102267.1 256378607 8328786 complement(5436139..5441916) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: pap:PSPA7_2859 peptide synthase; amino acid adenylation domain-containing protein 5441916 8328786 Amir_4588 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102267.1 5436139 R 446462 CDS YP_003102268.1 256378608 8328787 complement(5441913..5452958) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: dac:Daci_4753 amino acid adenylation domain- containing protein; amino acid adenylation domain-containing protein 5452958 8328787 Amir_4589 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102268.1 5441913 R 446462 CDS YP_003102269.1 256378609 8328788 5453084..5454121 1 NC_013093.1 KEGG: sus:Acid_4167 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 4-hydroxyphenylpyruvate dioxygenase 5454121 8328788 Amir_4590 Actinosynnema mirum DSM 43827 4-hydroxyphenylpyruvate dioxygenase YP_003102269.1 5453084 D 446462 CDS YP_003102270.1 256378610 8328789 5454137..5455432 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: hch:HCH_01676 transcriptional regulator; GntR family transcriptional regulator 5455432 8328789 Amir_4591 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003102270.1 5454137 D 446462 CDS YP_003102271.1 256378611 8328790 complement(5455474..5456700) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpe:KPK_3480 multidrug resistance protein MdtH; major facilitator superfamily protein 5456700 8328790 Amir_4592 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102271.1 5455474 R 446462 CDS YP_003102272.1 256378612 8328791 5456801..5457022 1 NC_013093.1 PFAM: MbtH domain protein; KEGG: scl:sce3255 hypothetical protein; MbtH domain-containing protein 5457022 8328791 Amir_4593 Actinosynnema mirum DSM 43827 MbtH domain-containing protein YP_003102272.1 5456801 D 446462 CDS YP_003102273.1 256378613 8328792 5457043..5458026 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mex:Mext_2357 D-cysteine desulfhydrase; pyridoxal-5'-phosphate-dependent protein beta subunit 5458026 8328792 Amir_4594 Actinosynnema mirum DSM 43827 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003102273.1 5457043 D 446462 CDS YP_003102274.1 256378614 8328793 5458029..5459063 1 NC_013093.1 KEGG: bte:BTH_II0297 LpqC; poly(3-hydroxybutyrate) depolymerase-like protein 5459063 8328793 Amir_4595 Actinosynnema mirum DSM 43827 poly(3-hydroxybutyrate) depolymerase-like protein YP_003102274.1 5458029 D 446462 CDS YP_003102275.1 256378615 8328794 complement(5459086..5460282) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: rpd:RPD_0041 cytochrome P450; cytochrome P450 5460282 8328794 Amir_4596 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003102275.1 5459086 R 446462 CDS YP_003102276.1 256378616 8328795 complement(5460312..5462060) 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: scl:sce8759 hypothetical protein; SARP family transcriptional regulator 5462060 8328795 Amir_4597 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003102276.1 5460312 R 446462 CDS YP_003102277.1 256378617 8328796 complement(5462153..5463283) 1 NC_013093.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: scl:sce7671 (S)-2-hydroxy-acid oxidase; FMN-dependent alpha-hydroxy acid dehydrogenase 5463283 8328796 Amir_4598 Actinosynnema mirum DSM 43827 FMN-dependent alpha-hydroxy acid dehydrogenase YP_003102277.1 5462153 R 446462 CDS YP_003102278.1 256378618 8328797 complement(5463890..5465227) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: mxa:MXAN_2304 cytochrome P450 family protein; cytochrome P450 5465227 8328797 Amir_4599 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003102278.1 5463890 R 446462 CDS YP_003102279.1 256378619 8328798 complement(5465375..5465596) 1 NC_013093.1 PFAM: MbtH domain protein; KEGG: cvi:CV_2232 MbtH-like protein; MbtH domain-containing protein 5465596 8328798 Amir_4600 Actinosynnema mirum DSM 43827 MbtH domain-containing protein YP_003102279.1 5465375 R 446462 CDS YP_003102280.1 256378620 8328799 complement(5465622..5466536) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 5466536 8328799 Amir_4601 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102280.1 5465622 R 446462 CDS YP_003102281.1 256378621 8328800 complement(5466565..5467713) 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: pag:PLES_17361 FAD-dependent monooxygenase; FAD-binding monooxygenase 5467713 8328800 Amir_4602 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102281.1 5466565 R 446462 CDS YP_003102282.1 256378622 8328801 complement(5467710..5470019) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; condensation domain protein; KEGG: pau:PA14_21000 hypothetical protein; short-chain dehydrogenase/reductase SDR 5470019 8328801 Amir_4603 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102282.1 5467710 R 446462 CDS YP_003102283.1 256378623 8328802 complement(5470016..5483839) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; beta- ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; condensation domain protein; acyl transferase; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pae:PA3327 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 5483839 8328802 Amir_4604 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102283.1 5470016 R 446462 CDS YP_003102284.1 256378624 8328803 5484257..5485666 1 NC_013093.1 PFAM: cytochrome P450; KEGG: rde:RD1_3506 cytochrome P450 family protein; cytochrome P450 5485666 8328803 Amir_4605 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003102284.1 5484257 D 446462 CDS YP_003102285.1 256378625 8328804 5485810..5487405 1 NC_013093.1 PFAM: carboxylesterase type B; KEGG: rpe:RPE_0251 carboxylesterase, type B; carboxylesterase type B 5487405 8328804 Amir_4606 Actinosynnema mirum DSM 43827 carboxylesterase type B YP_003102285.1 5485810 D 446462 CDS YP_003102286.1 256378626 8328805 complement(5487844..5489091) 1 NC_013093.1 KEGG: scl:sce0661 mannan endo-1,4-beta-mannosidase; hypothetical protein 5489091 8328805 Amir_4607 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102286.1 5487844 R 446462 CDS YP_003102287.1 256378627 8328806 complement(5489088..5490122) 1 NC_013093.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: scl:sce0662 LacI family transcription regulator; LacI family transcriptional regulator 5490122 8328806 Amir_4608 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003102287.1 5489088 R 446462 CDS YP_003102288.1 256378628 8328807 5490270..5491553 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH3845 ABC transporter (substrate-binding protein); family 1 extracellular solute-binding protein 5491553 8328807 Amir_4609 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003102288.1 5490270 D 446462 CDS YP_003102289.1 256378629 8328808 5491568..5492503 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlt:Rleg2_5350 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 5492503 8328808 Amir_4610 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102289.1 5491568 D 446462 CDS YP_003102290.1 256378630 8328809 5492525..5493376 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vei:Veis_0946 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 5493376 8328809 Amir_4611 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102290.1 5492525 D 446462 CDS YP_003102291.1 256378631 8328810 5493373..5495688 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: sus:Acid_6936 glycoside hydrolase family 3 protein; glycoside hydrolase family protein 5495688 8328810 Amir_4612 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003102291.1 5493373 D 446462 CDS YP_003102292.1 256378632 8328811 5495676..5496959 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: hypothetical LOC367592; K09704 hypothetical protein; hypothetical protein 5496959 8328811 Amir_4613 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102292.1 5495676 D 446462 CDS YP_003102293.1 256378633 8328812 complement(5496964..5497632) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mlo:mll1924 transcription regulator; TetR family transcriptional regulator 5497632 8328812 Amir_4614 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102293.1 5496964 R 446462 CDS YP_003102294.1 256378634 8328813 5497778..5498956 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: sme:SMc02891 oxidoreductase transmembrane protein; FAD-binding monooxygenase 5498956 8328813 Amir_4615 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102294.1 5497778 D 446462 CDS YP_003102295.1 256378635 8328814 5499190..5500044 1 NC_013093.1 KEGG: gur:Gura_2349 hypothetical protein; hypothetical protein 5500044 8328814 Amir_4616 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102295.1 5499190 D 446462 CDS YP_003102296.1 256378636 8328815 complement(5500111..5500491) 1 NC_013093.1 hypothetical protein 5500491 8328815 Amir_4617 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102296.1 5500111 R 446462 CDS YP_003102297.1 256378637 8328816 5500749..5501987 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: pst:PSPTO_4522 hypothetical protein; major facilitator superfamily protein 5501987 8328816 Amir_4618 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102297.1 5500749 D 446462 CDS YP_003102298.1 256378638 8328817 complement(5501991..5502794) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bpe:BP2854 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 5502794 8328817 Amir_4619 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102298.1 5501991 R 446462 CDS YP_003102299.1 256378639 8328818 5502890..5503474 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: acp:A2cp1_2482 transcriptional regulator, TetR family; TetR family transcriptional regulator 5503474 8328818 Amir_4620 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102299.1 5502890 D 446462 CDS YP_003102300.1 256378640 8328819 5503602..5505095 1 NC_013093.1 PFAM: Ricin B lectin; glycoside hydrolase family 5; SMART: Ricin B lectin; KEGG: scl:sce0748 Ricin precursor and poly(3- hydroxybutyrate) depolymerase fusion; Ricin B lectin 5505095 8328819 Amir_4621 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003102300.1 5503602 D 446462 CDS YP_003102301.1 256378641 8328820 5505178..5505954 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: scl:sce7498 short chain dehydrogenase; short chain dehydrogenase 5505954 8328820 Amir_4622 Actinosynnema mirum DSM 43827 short chain dehydrogenase YP_003102301.1 5505178 D 446462 CDS YP_003102302.1 256378642 8328821 5505971..5506864 1 NC_013093.1 PFAM: regulatory protein MerR; transcription activator effector binding; SMART: regulatory protein MerR; KEGG: cvi:CV_4236 MerR family transcriptional regulator; MerR family transcriptional regulator 5506864 8328821 Amir_4623 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003102302.1 5505971 D 446462 CDS YP_003102303.1 256378643 8328822 complement(5506842..5507843) 1 NC_013093.1 PFAM: regulatory protein MerR; PBS lyase HEAT domain protein repeat-containing protein; SMART: regulatory protein MerR; PBS lyase HEAT domain protein repeat-containing protein; KEGG: bur:Bcep18194_B2665 MerR family transcriptional regulator; MerR family transcriptional regulator 5507843 8328822 Amir_4624 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003102303.1 5506842 R 446462 CDS YP_003102304.1 256378644 8328823 complement(5507837..5508505) 1 NC_013093.1 KEGG: ppw:PputW619_5008 heat repeat-containing PBS lyase; hypothetical protein 5508505 8328823 Amir_4625 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102304.1 5507837 R 446462 CDS YP_003102305.1 256378645 8328824 5508825..5510438 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: pzu:PHZ_c2512 long-chain-fatty-acid--CoA ligase; AMP-dependent synthetase and ligase 5510438 8328824 Amir_4626 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102305.1 5508825 D 446462 CDS YP_003102306.1 256378646 8328825 5510435..5511136 1 NC_013093.1 KEGG: bsu:BSU35070 hypothetical protein; hypothetical protein 5511136 8328825 Amir_4627 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102306.1 5510435 D 446462 CDS YP_003102307.1 256378647 8328826 5511190..5511915 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; MCP methyltransferase CheR-type; KEGG: pfl:PFL_1036 ToxA protein; CheR-type MCP methyltransferase 5511915 8328826 Amir_4628 Actinosynnema mirum DSM 43827 CheR-type MCP methyltransferase YP_003102307.1 5511190 D 446462 CDS YP_003102308.1 256378648 8328828 complement(5512855..5513184) 1 NC_013093.1 PFAM: protein of unknown function DUF1330; KEGG: pde:Pden_4583 protein of unknown function DUF1330; hypothetical protein 5513184 8328828 Amir_4630 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102308.1 5512855 R 446462 CDS YP_003102309.1 256378649 8328829 5513246..5514061 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: transcriptional regulator, XRE family; XRE family transcriptional regulator 5514061 8328829 Amir_4631 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102309.1 5513246 D 446462 CDS YP_003102310.1 256378650 8328830 complement(5514078..5514965) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bpt:Bpet4146 LysR family transcriptional regulator; LysR family transcriptional regulator 5514965 8328830 Amir_4632 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102310.1 5514078 R 446462 CDS YP_003102311.1 256378651 8328831 5515035..5515982 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: met:M446_6836 threonine dehydratase; pyridoxal-5'-phosphate-dependent protein beta subunit 5515982 8328831 Amir_4633 Actinosynnema mirum DSM 43827 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003102311.1 5515035 D 446462 CDS YP_003102312.1 256378652 8328832 5516079..5520353 1 NC_013093.1 PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 42 domain 5 loop region; glycosyl hydrolase family 98 carbohydrate binding module; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; SMART: glycosyl hydrolase family 98 carbohydrate binding module; LamG domain protein jellyroll fold domain protein; KEGG: sus:Acid_4607 beta-galactosidase; glycoside hydrolase family protein 5520353 8328832 Amir_4634 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003102312.1 5516079 D 446462 CDS YP_003102313.1 256378653 8328833 complement(5520406..5520819) 1 NC_013093.1 hypothetical protein 5520819 8328833 Amir_4635 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102313.1 5520406 R 446462 CDS YP_003102314.1 256378654 8328834 complement(5520930..5521892) 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_0902 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator 5521892 8328834 Amir_4636 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102314.1 5520930 R 446462 CDS YP_003102315.1 256378655 8328835 complement(5522020..5522949) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: mlo:mlr2819 oxidoreductase; alcohol dehydrogenase GroES domain-containing protein 5522949 8328835 Amir_4637 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003102315.1 5522020 R 446462 CDS YP_003102316.1 256378656 8328836 5523082..5523579 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bch:Bcen2424_4743 MarR family transcriptional regulator; MarR family transcriptional regulator 5523579 8328836 Amir_4638 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003102316.1 5523082 D 446462 CDS YP_003102317.1 256378657 8328837 5523699..5525024 1 NC_013093.1 PFAM: amino acid permease-associated region; KEGG: lpc:LPC_0052 amino acid transporter, permease; amino acid permease-associated protein 5525024 8328837 Amir_4639 Actinosynnema mirum DSM 43827 amino acid permease-associated protein YP_003102317.1 5523699 D 446462 CDS YP_003102318.1 256378658 8328838 5525125..5525967 1 NC_013093.1 KEGG: sat:SYN_02434 hydrolase or acyltransferase; hypothetical protein 5525967 8328838 Amir_4640 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102318.1 5525125 D 446462 CDS YP_003102319.1 256378659 8328839 5525964..5526656 1 NC_013093.1 hypothetical protein 5526656 8328839 Amir_4641 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102319.1 5525964 D 446462 CDS YP_003102320.1 256378660 8328840 5526749..5527843 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: gur:Gura_3220 glycosyl transferase, group 1; group 1 glycosyl transferase 5527843 8328840 Amir_4642 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003102320.1 5526749 D 446462 CDS YP_003102321.1 256378661 8328841 5527860..5528660 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: bcm:Bcenmc03_0849 glycosyl transferase family protein; family 2 glycosyl transferase 5528660 8328841 Amir_4643 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003102321.1 5527860 D 446462 CDS YP_003102322.1 256378662 8328842 complement(5529317..5529937) 1 NC_013093.1 hypothetical protein 5529937 8328842 Amir_4644 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102322.1 5529317 R 446462 CDS YP_003102323.1 256378663 8328843 complement(5530090..5531103) 1 NC_013093.1 hypothetical protein 5531103 8328843 Amir_4645 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102323.1 5530090 R 446462 CDS YP_003102324.1 256378664 8328844 complement(5531325..5532425) 1 NC_013093.1 TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: oca:OCAR_6856 alcohol dehydrogenase class 3; mycothiol-dependent formaldehyde dehydrogenase 5532425 8328844 Amir_4646 Actinosynnema mirum DSM 43827 mycothiol-dependent formaldehyde dehydrogenase YP_003102324.1 5531325 R 446462 CDS YP_003102325.1 256378665 8328845 5532742..5533992 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: reu:Reut_B3953 major facilitator transporter; major facilitator superfamily protein 5533992 8328845 Amir_4647 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102325.1 5532742 D 446462 CDS YP_003102326.1 256378666 8328846 5534320..5535534 1 NC_013093.1 PFAM: protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: scl:sce5193 hypothetical protein; hypothetical protein 5535534 8328846 Amir_4648 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102326.1 5534320 D 446462 CDS YP_003102327.1 256378667 8328847 5535531..5536811 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: ank:AnaeK_4388 major facilitator superfamily MFS_1; major facilitator superfamily protein 5536811 8328847 Amir_4649 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102327.1 5535531 D 446462 CDS YP_003102328.1 256378668 8328848 5537170..5538774 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sdn:Sden_3736 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 5538774 8328848 Amir_4650 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102328.1 5537170 D 446462 CDS YP_003102329.1 256378669 8328849 5538818..5539066 1 NC_013093.1 PFAM: phosphopantetheine-binding; KEGG: mxa:MXAN_3631 polyketide synthase type I; phosphopantetheine-binding 5539066 8328849 Amir_4651 Actinosynnema mirum DSM 43827 phosphopantetheine-binding YP_003102329.1 5538818 D 446462 CDS YP_003102330.1 256378670 8328850 5539063..5540028 1 NC_013093.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bcy:Bcer98_3668 alpha/beta hydrolase domain- containing protein; alpha/beta hydrolase fold-3 domain-containing protein 5540028 8328850 Amir_4652 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold-3 domain-containing protein YP_003102330.1 5539063 D 446462 CDS YP_003102331.1 256378671 8328851 complement(5540074..5541123) 1 NC_013093.1 PFAM: transketolase; KEGG: bbt:BBta_4462 pyruvate dehydrogenase subunit beta; transketolase 5541123 8328851 Amir_4653 Actinosynnema mirum DSM 43827 transketolase YP_003102331.1 5540074 R 446462 CDS YP_003102332.1 256378672 8328852 complement(5541120..5542514) 1 NC_013093.1 TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: reu:Reut_B5023 3-carboxy-cis,cis-muconate cycloisomerase; 3-carboxy-cis,cis-muconate cycloisomerase 5542514 8328852 Amir_4654 Actinosynnema mirum DSM 43827 3-carboxy-cis,cis-muconate cycloisomerase YP_003102332.1 5541120 R 446462 CDS YP_003102333.1 256378673 8328853 complement(5542504..5544816) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 5544816 8328853 Amir_4655 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102333.1 5542504 R 446462 CDS YP_003102334.1 256378674 8328854 5545289..5546032 1 NC_013093.1 KEGG: bcz:BCZK1714 hypothetical protein; hypothetical protein 5546032 8328854 Amir_4656 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102334.1 5545289 D 446462 CDS YP_003102335.1 256378675 8328855 5546154..5547251 1 NC_013093.1 KEGG: bja:blr1218 hypothetical protein; hypothetical protein 5547251 8328855 Amir_4657 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102335.1 5546154 D 446462 CDS YP_003102336.1 256378676 8328856 5547438..5548211 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: short chain dehydrogenase protein; short-chain dehydrogenase/reductase SDR 5548211 8328856 Amir_4658 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102336.1 5547438 D 446462 CDS YP_003102337.1 256378677 8328857 5548489..5549208 1 NC_013093.1 hypothetical protein 5549208 8328857 Amir_4659 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102337.1 5548489 D 446462 CDS YP_003102338.1 256378678 8328858 5549427..5550164 1 NC_013093.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: dps:DP1551 hypothetical protein; nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase 5550164 8328858 Amir_4660 Actinosynnema mirum DSM 43827 nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase YP_003102338.1 5549427 D 446462 CDS YP_003102339.1 256378679 8328859 5550161..5551153 1 NC_013093.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bcy:Bcer98_3668 alpha/beta hydrolase domain- containing protein; alpha/beta hydrolase fold-3 domain-containing protein 5551153 8328859 Amir_4661 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold-3 domain-containing protein YP_003102339.1 5550161 D 446462 CDS YP_003102340.1 256378680 8328860 5551387..5552238 1 NC_013093.1 KEGG: xcb:XC_3673 hypothetical protein; hypothetical protein 5552238 8328860 Amir_4662 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102340.1 5551387 D 446462 CDS YP_003102341.1 256378681 8328861 complement(5552303..5553307) 1 NC_013093.1 PFAM: pectinesterase; KEGG: xop:PXO_00373 pectinesterase; pectinesterase 5553307 8328861 Amir_4663 Actinosynnema mirum DSM 43827 pectinesterase YP_003102341.1 5552303 R 446462 CDS YP_003102342.1 256378682 8328862 complement(5553359..5554216) 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: bsu:BSU07020 hypothetical protein; G-D-S-L family lipolytic protein 5554216 8328862 Amir_4664 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003102342.1 5553359 R 446462 CDS YP_003102343.1 256378683 8328863 5554572..5554952 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rlt:Rleg2_1526 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase 5554952 8328863 Amir_4665 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003102343.1 5554572 D 446462 CDS YP_003102344.1 256378684 8328864 complement(5555206..5555433) 1 NC_013093.1 KEGG: bha:BH0581 two-component response regulator; response regulator receiver protein 5555433 8328864 Amir_4666 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003102344.1 5555206 R 446462 CDS YP_003102345.1 256378685 8328865 complement(5555468..5555851) 1 NC_013093.1 hypothetical protein 5555851 8328865 Amir_4667 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102345.1 5555468 R 446462 CDS YP_003102346.1 256378686 8328866 complement(5555848..5556288) 1 NC_013093.1 KEGG: ilo:IL0311 ABC-type multidrug transport system, permease component; multidrug ABC transporter permease 5556288 8328866 Amir_4668 Actinosynnema mirum DSM 43827 multidrug ABC transporter permease YP_003102346.1 5555848 R 446462 CDS YP_003102347.1 256378687 8328867 complement(5556285..5556860) 1 NC_013093.1 PFAM: ABC transporter; KEGG: ccs:CCNA_01205 ABC transporter ATP-binding protein; ABC transporter ATP-binding protein 5556860 8328867 Amir_4669 Actinosynnema mirum DSM 43827 ABC transporter ATP-binding protein YP_003102347.1 5556285 R 446462 CDS YP_003102348.1 256378688 8328868 5556986..5557879 1 NC_013093.1 KEGG: atc:AGR_pAT_397 hypothetical protein; hypothetical protein 5557879 8328868 Amir_4670 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102348.1 5556986 D 446462 CDS YP_003102349.1 256378689 8328869 5557876..5558739 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: bcj:BCAM1565 monooxygenase; luciferase-like monooxygenase 5558739 8328869 Amir_4671 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003102349.1 5557876 D 446462 CDS YP_003102350.1 256378690 8328870 5558860..5559504 1 NC_013093.1 KEGG: sun:SUN_0435 hypothetical protein; hypothetical protein 5559504 8328870 Amir_4672 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102350.1 5558860 D 446462 CDS YP_003102351.1 256378691 8328871 5559679..5560674 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: hypothetical protein; G-D-S-L family lipolytic protein 5560674 8328871 Amir_4673 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003102351.1 5559679 D 446462 CDS YP_003102352.1 256378692 8328872 5560676..5561680 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce5722 endo-1,4-beta-glucanase; G-D-S-L family lipolytic protein 5561680 8328872 Amir_4674 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003102352.1 5560676 D 446462 CDS YP_003102353.1 256378693 8328873 5561700..5561861 1 NC_013093.1 hypothetical protein 5561861 8328873 Amir_4675 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102353.1 5561700 D 446462 CDS YP_003102354.1 256378694 8328874 complement(5561862..5562215) 1 NC_013093.1 KEGG: scl:sce8365 hypothetical protein; hypothetical protein 5562215 8328874 Amir_4676 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102354.1 5561862 R 446462 CDS YP_003102355.1 256378695 8328875 complement(5562291..5562440) 1 NC_013093.1 hypothetical protein 5562440 8328875 Amir_4677 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102355.1 5562291 R 446462 CDS YP_003102356.1 256378696 8328876 5562458..5563105 1 NC_013093.1 KEGG: abo:ABO_1927 hypothetical protein; hypothetical protein 5563105 8328876 Amir_4678 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102356.1 5562458 D 446462 CDS YP_003102357.1 256378697 8328877 complement(5563107..5564879) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_5176 serine/threonine protein kinase; serine/threonine protein kinase 5564879 8328877 Amir_4679 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003102357.1 5563107 R 446462 CDS YP_003102358.1 256378698 8328880 5566698..5568479 1 NC_013093.1 PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: ccs:CCNA_03254 pectate lyase; cellulose-binding family protein 5568479 8328880 Amir_4682 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003102358.1 5566698 D 446462 CDS YP_003102359.1 256378699 8328881 complement(5568526..5569683) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: cvi:CV_0711 TetR family transcriptional regulator; TetR family transcriptional regulator 5569683 8328881 Amir_4683 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102359.1 5568526 R 446462 CDS YP_003102360.1 256378700 8328882 5569905..5571485 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA2050 ADP-producing CoA ligase, feruloyl-CoA synthetase; AMP-dependent synthetase and ligase 5571485 8328882 Amir_4684 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102360.1 5569905 D 446462 CDS YP_003102361.1 256378701 8328883 complement(5571598..5573214) 1 NC_013093.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase 5573214 gabD2 8328883 gabD2 Actinosynnema mirum DSM 43827 succinic semialdehyde dehydrogenase YP_003102361.1 5571598 R 446462 CDS YP_003102362.1 256378702 8328884 5573387..5574598 1 NC_013093.1 KEGG: scl:sce5500 hypothetical protein; hypothetical protein 5574598 8328884 Amir_4686 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102362.1 5573387 D 446462 CDS YP_003102363.1 256378703 8328885 5574765..5575886 1 NC_013093.1 PFAM: beta-lactamase; KEGG: scl:sce3869 hypothetical protein; Serine-type D-Ala-D-Ala carboxypeptidase 5575886 8328885 Amir_4687 Actinosynnema mirum DSM 43827 Serine-type D-Ala-D-Ala carboxypeptidase YP_003102363.1 5574765 D 446462 CDS YP_003102364.1 256378704 8328886 5575877..5577136 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: bme:BMEI1583 sensor protein DegS; histidine kinase 5577136 8328886 Amir_4688 Actinosynnema mirum DSM 43827 histidine kinase YP_003102364.1 5575877 D 446462 CDS YP_003102365.1 256378705 8328887 5577124..5577774 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; response regulator receiver; KEGG: bsu:BSU08300 hypothetical protein; LuxR family transcriptional regulator 5577774 8328887 Amir_4689 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102365.1 5577124 D 446462 CDS YP_003102366.1 256378706 8328888 5577789..5577884 1 NC_013093.1 hypothetical protein 5577884 8328888 Amir_4690 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102366.1 5577789 D 446462 CDS YP_003102367.1 256378707 8328889 complement(5577939..5579090) 1 NC_013093.1 PFAM: beta-lactamase; KEGG: scl:sce3868 alkaline D-peptidase; Serine-type D-Ala-D-Ala carboxypeptidase 5579090 8328889 Amir_4691 Actinosynnema mirum DSM 43827 Serine-type D-Ala-D-Ala carboxypeptidase YP_003102367.1 5577939 R 446462 CDS YP_003102368.1 256378708 8328890 complement(5579180..5580208) 1 NC_013093.1 KEGG: eba:ebA5037 hypothetical protein; hypothetical protein 5580208 8328890 Amir_4692 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102368.1 5579180 R 446462 CDS YP_003102369.1 256378709 8328891 5580423..5581085 1 NC_013093.1 PFAM: chitin-binding domain 3 protein; KEGG: cvi:CV_0554 carbohydrate-binding protein; chitin-binding domain 3 protein 5581085 8328891 Amir_4693 Actinosynnema mirum DSM 43827 chitin-binding domain 3 protein YP_003102369.1 5580423 D 446462 CDS YP_003102370.1 256378710 8328892 5581888..5584389 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: sme:SMa0464 adenylate/guanylate cyclase; SARP family transcriptional regulator 5584389 8328892 Amir_4694 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003102370.1 5581888 D 446462 CDS YP_003102371.1 256378711 8328893 5584548..5586101 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: ppu:PP_2782 pyridoxalphosphate dependent aminotransferase, class III; class III aminotransferase 5586101 8328893 Amir_4695 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003102371.1 5584548 D 446462 CDS YP_003102372.1 256378712 8328894 5586098..5587270 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: bsu:BSU18260 hypothetical protein; acyl-CoA dehydrogenase domain-containing protein 5587270 8328894 Amir_4696 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003102372.1 5586098 D 446462 CDS YP_003102373.1 256378713 8328895 complement(5587362..5587769) 1 NC_013093.1 KEGG: pap:PSPA7_2619 hypothetical protein; hypothetical protein 5587769 8328895 Amir_4697 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102373.1 5587362 R 446462 CDS YP_003102374.1 256378714 8328896 complement(5587851..5594192) 1 NC_013093.1 TIGRFAM: thioester reductase domain protein; PFAM: Male sterility domain; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; 3- beta hydroxysteroid dehydrogenase/isomerase; acyl transferase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: pst:PSPTO_4687 coronafacic acid polyketide synthetase II; thioester reductase domain-containing protein 5594192 8328896 Amir_4698 Actinosynnema mirum DSM 43827 thioester reductase domain-containing protein YP_003102374.1 5587851 R 446462 CDS YP_003102375.1 256378715 8328897 complement(5594239..5606481) 1 NC_013093.1 PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; phosphopantetheine-binding; KEGG: met:M446_0170 beta-ketoacyl synthase; Mycocerosate synthase., erythronolide synthase 5606481 8328897 Amir_4699 Actinosynnema mirum DSM 43827 Mycocerosate synthase., erythronolide synthase YP_003102375.1 5594239 R 446462 CDS YP_003102376.1 256378716 8328898 5606723..5607262 1 NC_013093.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: bpy:Bphyt_1723 flavin reductase domain protein FMN-binding; flavin reductase domain-containing protein 5607262 8328898 Amir_4700 Actinosynnema mirum DSM 43827 flavin reductase domain-containing protein YP_003102376.1 5606723 D 446462 CDS YP_003102377.1 256378717 8328899 5607479..5608024 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 5608024 8328899 Amir_4701 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003102377.1 5607479 D 446462 CDS YP_003102378.1 256378718 8328900 complement(5608166..5609017) 1 NC_013093.1 PFAM: NmrA family protein; KEGG: afw:Anae109_3754 NmrA family protein; NmrA family protein 5609017 8328900 Amir_4702 Actinosynnema mirum DSM 43827 NmrA family protein YP_003102378.1 5608166 R 446462 CDS YP_003102379.1 256378719 8328901 complement(5609217..5610398) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: rsh:Rsph17029_3744 acyl-CoA dehydrogenase type 2; acyl-CoA dehydrogenase type 2 domain-containing protein 5610398 8328901 Amir_4703 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003102379.1 5609217 R 446462 CDS YP_003102380.1 256378720 8328902 complement(5610713..5612149) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: transporter protein; major facilitator superfamily protein 5612149 8328902 Amir_4704 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102380.1 5610713 R 446462 CDS YP_003102381.1 256378721 8328903 5612274..5612720 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: hypothetical protein; HxlR family transcriptional regulator 5612720 8328903 Amir_4705 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003102381.1 5612274 D 446462 CDS YP_003102382.1 256378722 8328904 complement(5612783..5613184) 1 NC_013093.1 KEGG: pap:PSPA7_2619 hypothetical protein; hypothetical protein 5613184 8328904 Amir_4706 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102382.1 5612783 R 446462 CDS YP_003102383.1 256378723 8328905 complement(5613245..5614432) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: rlt:Rleg2_5725 acyl-CoA dehydrogenase type 2 domain; acyl-CoA dehydrogenase type 2 domain-containing protein 5614432 8328905 Amir_4707 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase type 2 domain-containing protein YP_003102383.1 5613245 R 446462 CDS YP_003102384.1 256378724 8328906 5614664..5615083 1 NC_013093.1 KEGG: sus:Acid_5966 hypothetical protein; hypothetical protein 5615083 8328906 Amir_4708 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102384.1 5614664 D 446462 CDS YP_003102385.1 256378725 8328907 5615253..5615618 1 NC_013093.1 KEGG: aav:Aave_2096 transcriptional regulator, ArsR family; hypothetical protein 5615618 8328907 Amir_4709 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102385.1 5615253 D 446462 CDS YP_003102386.1 256378726 8328908 complement(5615801..5617315) 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: sde:Sde_0644 hypothetical protein; TAP domain-containing protein 5617315 8328908 Amir_4710 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003102386.1 5615801 R 446462 CDS YP_003102387.1 256378727 8328909 complement(5617627..5619573) 1 NC_013093.1 KEGG: rme:Rmet_4641 ATP-dependent endonuclease of the OLD family-like protein; ATP-dependent endonuclease of the OLD family- like protein 5619573 8328909 Amir_4711 Actinosynnema mirum DSM 43827 ATP-dependent endonuclease of the OLD family- like protein YP_003102387.1 5617627 R 446462 CDS YP_003102388.1 256378728 8328910 complement(5619780..5622425) 1 NC_013093.1 PFAM: protein of unknown function DUF1680; KEGG: hypothetical protein; hypothetical protein 5622425 8328910 Amir_4712 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102388.1 5619780 R 446462 CDS YP_003102389.1 256378729 8328911 complement(5622422..5623783) 1 NC_013093.1 PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: scl:sce8667 hypothetical protein; Xaa-Pro aminopeptidase 5623783 8328911 Amir_4713 Actinosynnema mirum DSM 43827 Xaa-Pro aminopeptidase YP_003102389.1 5622422 R 446462 CDS YP_003102390.1 256378730 8328912 complement(5623794..5625113) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: rle:pRL100270 proline iminopeptidase; alpha/beta hydrolase fold protein 5625113 8328912 Amir_4714 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003102390.1 5623794 R 446462 CDS YP_003102391.1 256378731 8328913 complement(5625110..5626090) 1 NC_013093.1 PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: dol:Dole_0940 oligopeptide/dipeptide ABC transporter, ATPase subunit; ABC transporter 5626090 8328913 Amir_4715 Actinosynnema mirum DSM 43827 ABC transporter YP_003102391.1 5625110 R 446462 CDS YP_003102392.1 256378732 8328914 complement(5626087..5626902) 1 NC_013093.1 PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: bja:bll2870 ABC transporter ATP-binding protein; ABC transporter 5626902 8328914 Amir_4716 Actinosynnema mirum DSM 43827 ABC transporter YP_003102392.1 5626087 R 446462 CDS YP_003102393.1 256378733 8328915 complement(5626899..5627897) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: peptide transport system permease protein; K02033 peptide/nickel transport system permease protein; ABC transporter inner membrane protein 5627897 8328915 Amir_4717 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102393.1 5626899 R 446462 CDS YP_003102394.1 256378734 8328916 complement(5627894..5628850) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: gme:Gmet_1236 binding-protein dependent transport system inner membrane protein; ABC transporter inner membrane protein 5628850 8328916 Amir_4718 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102394.1 5627894 R 446462 CDS YP_003102395.1 256378735 8328917 complement(5628855..5630549) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: rle:pRL110448 substrate-binding ABC transporter protein; 4-phytase 5630549 8328917 Amir_4719 Actinosynnema mirum DSM 43827 4-phytase YP_003102395.1 5628855 R 446462 CDS YP_003102396.1 256378736 8328918 complement(5631077..5631748) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bbr:BB0470 GntR family transcriptional regulator; GntR family transcriptional regulator 5631748 8328918 Amir_4720 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003102396.1 5631077 R 446462 CDS YP_003102397.1 256378737 8328919 complement(5631866..5633239) 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_02881 oxoglutarate semialdehyde dehydrogenase; aldehyde dehydrogenase 5633239 8328919 Amir_4721 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003102397.1 5631866 R 446462 CDS YP_003102398.1 256378738 8328920 complement(5633250..5634251) 1 NC_013093.1 PFAM: proline racemase; KEGG: bat:BAS2643 proline racemase; proline racemase 5634251 8328920 Amir_4722 Actinosynnema mirum DSM 43827 proline racemase YP_003102398.1 5633250 R 446462 CDS YP_003102399.1 256378739 8328921 complement(5634253..5635185) 1 NC_013093.1 PFAM: dihydrodipicolinate synthetase; KEGG: swd:Swoo_2822 dihydrodipicolinate synthetase; dihydrodipicolinate synthetase 5635185 8328921 Amir_4723 Actinosynnema mirum DSM 43827 dihydrodipicolinate synthetase YP_003102399.1 5634253 R 446462 CDS YP_003102400.1 256378740 8328922 complement(5635182..5636585) 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: bph:Bphy_4670 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 5636585 8328922 Amir_4724 Actinosynnema mirum DSM 43827 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_003102400.1 5635182 R 446462 CDS YP_003102401.1 256378741 8328923 complement(5636578..5636835) 1 NC_013093.1 KEGG: vei:Veis_0721 FAD dependent oxidoreductase; FAD dependent oxidoreductase 5636835 8328923 Amir_4725 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003102401.1 5636578 R 446462 CDS YP_003102402.1 256378742 8328924 complement(5636832..5638001) 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: bce:BC2836 sarcosine oxidase beta subunit; FAD dependent oxidoreductase 5638001 8328924 Amir_4726 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003102402.1 5636832 R 446462 CDS YP_003102403.1 256378743 8328925 complement(5638415..5638918) 1 NC_013093.1 hypothetical protein 5638918 8328925 Amir_4727 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102403.1 5638415 R 446462 CDS YP_003102404.1 256378744 8328926 5639694..5640359 1 NC_013093.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5640359 8328926 Amir_4728 Actinosynnema mirum DSM 43827 deoxyribose-phosphate aldolase YP_003102404.1 5639694 D 446462 CDS YP_003102405.1 256378745 8328927 5640505..5641533 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bac:BamMC406_6022 LacI family transcription regulator; LacI family transcriptional regulator 5641533 8328927 Amir_4729 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003102405.1 5640505 D 446462 CDS YP_003102406.1 256378746 8328928 5641562..5642863 1 NC_013093.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5642863 deoA 8328928 deoA Actinosynnema mirum DSM 43827 thymidine phosphorylase YP_003102406.1 5641562 D 446462 CDS YP_003102407.1 256378747 8328929 5643007..5644479 1 NC_013093.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: scl:sce1158 hypothetical protein; amidohydrolase 5644479 8328929 Amir_4731 Actinosynnema mirum DSM 43827 amidohydrolase YP_003102407.1 5643007 D 446462 CDS YP_003102408.1 256378748 8328930 complement(5644553..5645908) 1 NC_013093.1 KEGG: glycosyl hydrolase family 10 protein; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase 5645908 8328930 Amir_4732 Actinosynnema mirum DSM 43827 endo-1,4-beta-xylanase YP_003102408.1 5644553 R 446462 CDS YP_003102409.1 256378749 8328931 complement(5646080..5646982) 1 NC_013093.1 hypothetical protein 5646982 8328931 Amir_4733 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102409.1 5646080 R 446462 CDS YP_003102410.1 256378750 8328932 5647196..5647891 1 NC_013093.1 hypothetical protein 5647891 8328932 Amir_4734 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102410.1 5647196 D 446462 CDS YP_003102411.1 256378751 8328933 5647888..5648655 1 NC_013093.1 KEGG: ade:Adeh_2319 hypothetical protein; hypothetical protein 5648655 8328933 Amir_4735 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102411.1 5647888 D 446462 CDS YP_003102412.1 256378752 8328935 complement(5649397..5649846) 1 NC_013093.1 KEGG: pzu:PHZ_c0663 type II secretion system protein N; hypothetical protein 5649846 8328935 Amir_4737 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102412.1 5649397 R 446462 CDS YP_003102413.1 256378753 8328936 complement(5649849..5651000) 1 NC_013093.1 KEGG: smd:Smed_1835 hypothetical protein; hypothetical protein 5651000 8328936 Amir_4738 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102413.1 5649849 R 446462 CDS YP_003102414.1 256378754 8328937 complement(5651000..5651296) 1 NC_013093.1 hypothetical protein 5651296 8328937 Amir_4739 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102414.1 5651000 R 446462 CDS YP_003102415.1 256378755 8328938 complement(5651559..5652407) 1 NC_013093.1 KEGG: ank:AnaeK_3866 hypothetical protein; hypothetical protein 5652407 8328938 Amir_4740 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102415.1 5651559 R 446462 CDS YP_003102416.1 256378756 8328939 complement(5652530..5653096) 1 NC_013093.1 KEGG: pna:Pnap_3074 hypothetical protein; hypothetical protein 5653096 8328939 Amir_4741 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102416.1 5652530 R 446462 CDS YP_003102417.1 256378757 8328940 complement(5653093..5654448) 1 NC_013093.1 KEGG: ank:AnaeK_1466 hypothetical protein; hypothetical protein 5654448 8328940 Amir_4742 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102417.1 5653093 R 446462 CDS YP_003102418.1 256378758 8328941 complement(5654448..5655251) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mmr:Mmar10_2631 ABC transporter; ABC transporter 5655251 8328941 Amir_4743 Actinosynnema mirum DSM 43827 ABC transporter YP_003102418.1 5654448 R 446462 CDS YP_003102419.1 256378759 8328942 complement(5655401..5656192) 1 NC_013093.1 KEGG: mpo:Mpop_3497 integral membrane protein MviN; hypothetical protein 5656192 8328942 Amir_4744 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102419.1 5655401 R 446462 CDS YP_003102420.1 256378760 8328943 complement(5656189..5656740) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: pla:Plav_1868 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit 5656740 8328943 Amir_4745 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102420.1 5656189 R 446462 CDS YP_003102421.1 256378761 8328944 complement(5656977..5657804) 1 NC_013093.1 KEGG: rme:Rmet_3224 hypothetical protein; hypothetical protein 5657804 8328944 Amir_4746 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102421.1 5656977 R 446462 CDS YP_003102422.1 256378762 8328945 complement(5657961..5659394) 1 NC_013093.1 PFAM: NAD(P) transhydrogenase beta subunit; KEGG: abo:ABO_1327 pyridine nucleotide transhydrogenase, B subunit; NAD(P)(+) transhydrogenase 5659394 8328945 Amir_4747 Actinosynnema mirum DSM 43827 NAD(P)(+) transhydrogenase YP_003102422.1 5657961 R 446462 CDS YP_003102423.1 256378763 8328946 complement(5659391..5659765) 1 NC_013093.1 KEGG: afw:Anae109_2972 pyridine nucleotide transhydrogenase alpha subunit-like protein; NAD/NADP transhydrogenase alpha subunit-like protein 5659765 8328946 Amir_4748 Actinosynnema mirum DSM 43827 NAD/NADP transhydrogenase alpha subunit-like protein YP_003102423.1 5659391 R 446462 CDS YP_003102424.1 256378764 8328947 complement(5659765..5660886) 1 NC_013093.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: tgr:Tgr7_0268 NAD(P)(+) transhydrogenase (AB- specific); alanine dehydrogenase/PNT domain-containing protein 5660886 8328947 Amir_4749 Actinosynnema mirum DSM 43827 alanine dehydrogenase/PNT domain-containing protein YP_003102424.1 5659765 R 446462 CDS YP_003102425.1 256378765 8328948 complement(5661119..5661763) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sus:Acid_0202 hypothetical protein; GCN5-like N-acetyltransferase 5661763 8328948 Amir_4750 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003102425.1 5661119 R 446462 CDS YP_003102426.1 256378766 8328949 complement(5661779..5662504) 1 NC_013093.1 KEGG: bha:BH0230 hypothetical protein; hypothetical protein 5662504 8328949 Amir_4751 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102426.1 5661779 R 446462 CDS YP_003102427.1 256378767 8328950 complement(5662504..5663871) 1 NC_013093.1 PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: oca:OCAR_7249 copper-containing nitrite reductase; nitrite reductase (NO-forming) 5663871 8328950 Amir_4752 Actinosynnema mirum DSM 43827 nitrite reductase (NO-forming) YP_003102427.1 5662504 R 446462 CDS YP_003102428.1 256378768 8328951 complement(5663868..5665109) 1 NC_013093.1 KEGG: tbd:Tbd_2176 hypothetical protein; hypothetical protein 5665109 8328951 Amir_4753 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102428.1 5663868 R 446462 CDS YP_003102429.1 256378769 8328952 complement(5665106..5666188) 1 NC_013093.1 KEGG: dar:Daro_3949 hypothetical protein; hypothetical protein 5666188 8328952 Amir_4754 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102429.1 5665106 R 446462 CDS YP_003102430.1 256378770 8328953 complement(5666188..5666874) 1 NC_013093.1 KEGG: ank:AnaeK_1843 SpoIID/LytB domain protein; transcriptional regulator 5666874 8328953 Amir_4755 Actinosynnema mirum DSM 43827 transcriptional regulator YP_003102430.1 5666188 R 446462 CDS YP_003102431.1 256378771 8328954 complement(5666935..5668914) 1 NC_013093.1 PFAM: peptidase M48 Ste24p; KEGG: acp:A2cp1_3025 peptidase M48 Ste24p; peptidase M48 Ste24p 5668914 8328954 Amir_4756 Actinosynnema mirum DSM 43827 peptidase M48 Ste24p YP_003102431.1 5666935 R 446462 CDS YP_003102432.1 256378772 8328955 complement(5668904..5669356) 1 NC_013093.1 KEGG: pla:Plav_2920 ubiquinol-cytochrome C chaperone; ubiquinol-cytochrome C chaperone 5669356 8328955 Amir_4757 Actinosynnema mirum DSM 43827 ubiquinol-cytochrome C chaperone YP_003102432.1 5668904 R 446462 CDS YP_003102433.1 256378773 8328956 5669632..5672106 1 NC_013093.1 PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; KEGG: bba:Bd3234 carboxypeptidase T precursor; peptidase M14 carboxypeptidase A 5672106 8328956 Amir_4758 Actinosynnema mirum DSM 43827 peptidase M14 carboxypeptidase A YP_003102433.1 5669632 D 446462 CDS YP_003102434.1 256378774 8328957 complement(5672231..5672353) 1 NC_013093.1 hypothetical protein 5672353 8328957 Amir_4759 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102434.1 5672231 R 446462 CDS YP_003102435.1 256378775 8328958 5672456..5672983 1 NC_013093.1 SMART: calcium-binding EF-hand-containing protein; KEGG: Hypothetical protein CBG02402; calcium-binding EF-hand-containing protein 5672983 8328958 Amir_4760 Actinosynnema mirum DSM 43827 calcium-binding EF-hand-containing protein YP_003102435.1 5672456 D 446462 CDS YP_003102436.1 256378776 8328959 5672987..5673928 1 NC_013093.1 TIGRFAM: methyltransferase; PFAM: O-methyltransferase; KEGG: bur:Bcep18194_B1573 protein of unknown function Mtu_121; methyltransferase 5673928 8328959 Amir_4761 Actinosynnema mirum DSM 43827 methyltransferase YP_003102436.1 5672987 D 446462 CDS YP_003102437.1 256378777 8328960 5674008..5674184 1 NC_013093.1 KEGG: bvi:Bcep1808_5626 transposase, IS4 family protein; transposase, IS4 family protein 5674184 8328960 Amir_4762 Actinosynnema mirum DSM 43827 transposase, IS4 family protein YP_003102437.1 5674008 D 446462 CDS YP_003102438.1 256378778 8328961 complement(5674234..5674683) 1 NC_013093.1 PFAM: DoxX family protein; KEGG: scl:sce3628 hypothetical protein; DoxX family protein 5674683 8328961 Amir_4763 Actinosynnema mirum DSM 43827 DoxX family protein YP_003102438.1 5674234 R 446462 CDS YP_003102439.1 256378779 8328962 5674880..5675425 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: met:M446_2111 TetR family transcriptional regulator; TetR family transcriptional regulator 5675425 8328962 Amir_4764 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102439.1 5674880 D 446462 CDS YP_003102440.1 256378780 8328963 5675864..5679514 1 NC_013093.1 KEGG: dar:Daro_3601 hypothetical protein; hypothetical protein 5679514 8328963 Amir_4765 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102440.1 5675864 D 446462 CDS YP_003102441.1 256378781 8328964 5679495..5680073 1 NC_013093.1 hypothetical protein 5680073 8328964 Amir_4766 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102441.1 5679495 D 446462 CDS YP_003102442.1 256378782 8328966 5680797..5682326 1 NC_013093.1 PFAM: periplasmic solute binding protein; KEGG: bra:BRADO6268 ABC transporter substrate- binding protein; periplasmic solute binding protein 5682326 8328966 Amir_4768 Actinosynnema mirum DSM 43827 periplasmic solute binding protein YP_003102442.1 5680797 D 446462 CDS YP_003102443.1 256378783 8328967 5682314..5683150 1 NC_013093.1 KEGG: GK21128 gene product from transcript GK21128- RA; hypothetical protein 5683150 8328967 Amir_4769 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102443.1 5682314 D 446462 CDS YP_003102444.1 256378784 8328968 5683143..5683895 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcz:pE33L54_0038 manganese ABC transporter, ATP-binding protein; ABC transporter 5683895 8328968 Amir_4770 Actinosynnema mirum DSM 43827 ABC transporter YP_003102444.1 5683143 D 446462 CDS YP_003102445.1 256378785 8328969 5683892..5684755 1 NC_013093.1 PFAM: ABC transporter; KEGG: bha:BH1390 hypothetical protein; ABC transporter 5684755 8328969 Amir_4771 Actinosynnema mirum DSM 43827 ABC transporter YP_003102445.1 5683892 D 446462 CDS YP_003102446.1 256378786 8328970 complement(5684723..5685838) 1 NC_013093.1 KEGG: pin:Ping_0445 colicin uptake-like protein; hypothetical protein 5685838 8328970 Amir_4772 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102446.1 5684723 R 446462 CDS YP_003102447.1 256378787 8328971 complement(5685907..5687040) 1 NC_013093.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: cko:CKO_00925 hypothetical protein; cobalamin synthesis protein P47K 5687040 8328971 Amir_4773 Actinosynnema mirum DSM 43827 cobalamin synthesis protein P47K YP_003102447.1 5685907 R 446462 CDS YP_003102448.1 256378788 8328972 complement(5687063..5688067) 1 NC_013093.1 PFAM: protein of unknown function DUF916 cell surface KEGG: bcj:BCAM2172 patatin-like phospholipase; hypothetical protein 5688067 8328972 Amir_4774 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102448.1 5687063 R 446462 CDS YP_003102449.1 256378789 8328973 complement(5688166..5689644) 1 NC_013093.1 KEGG: mno:Mnod_2545 hypothetical protein; hypothetical protein 5689644 8328973 Amir_4775 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102449.1 5688166 R 446462 CDS YP_003102450.1 256378790 8328974 complement(5689751..5691541) 1 NC_013093.1 KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein 5691541 8328974 Amir_4776 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102450.1 5689751 R 446462 CDS YP_003102451.1 256378791 8328975 complement(5691749..5692993) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE2035 membrane transport protein; major facilitator superfamily protein 5692993 8328975 Amir_4777 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102451.1 5691749 R 446462 CDS YP_003102452.1 256378792 8328976 5693219..5693950 1 NC_013093.1 PFAM: methyltransferase small; KEGG: rpe:RPE_0637 methyltransferase small; methyltransferase small 5693950 8328976 Amir_4778 Actinosynnema mirum DSM 43827 methyltransferase small YP_003102452.1 5693219 D 446462 CDS YP_003102453.1 256378793 8328977 5693947..5694759 1 NC_013093.1 KEGG: pca:Pcar_1737 hypothetical protein; hypothetical protein 5694759 8328977 Amir_4779 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102453.1 5693947 D 446462 CDS YP_003102454.1 256378794 8328978 5694815..5695750 1 NC_013093.1 PFAM: GHMP kinase; KEGG: mlo:mlr9540 hypothetical protein; GHMP kinase 5695750 8328978 Amir_4780 Actinosynnema mirum DSM 43827 GHMP kinase YP_003102454.1 5694815 D 446462 CDS YP_003102455.1 256378795 8328979 5695829..5696833 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bpd:BURPS668_2001 cysteine synthase; pyridoxal-5'-phosphate-dependent protein beta subunit 5696833 8328979 Amir_4781 Actinosynnema mirum DSM 43827 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003102455.1 5695829 D 446462 CDS YP_003102456.1 256378796 8328980 complement(5696891..5697874) 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: ABC transporter substrate binding protein (iron); K02016 iron complex transport system substrate-binding protein; periplasmic binding protein 5697874 8328980 Amir_4782 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003102456.1 5696891 R 446462 CDS YP_003102457.1 256378797 8328981 complement(5697871..5698662) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcj:BCAL1346 Fe uptake system ATP- binding protein; ABC transporter 5698662 8328981 Amir_4783 Actinosynnema mirum DSM 43827 ABC transporter YP_003102457.1 5697871 R 446462 CDS YP_003102458.1 256378798 8328982 complement(5698659..5699720) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: dac:Daci_3791 transport system permease protein; transport system permease 5699720 8328982 Amir_4784 Actinosynnema mirum DSM 43827 transport system permease YP_003102458.1 5698659 R 446462 CDS YP_003102459.1 256378799 8328983 5699850..5700653 1 NC_013093.1 PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: mca:MCA3003 UbiE/COQ5 family methlytransferase; type 11 methyltransferase 5700653 8328983 Amir_4785 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003102459.1 5699850 D 446462 CDS YP_003102460.1 256378800 8328984 complement(5700763..5701332) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rec:RHECIAT_CH0000638 probable transcriptional regulator protein, TetR family; TetR family transcriptional regulator 5701332 8328984 Amir_4786 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102460.1 5700763 R 446462 CDS YP_003102461.1 256378801 8328985 complement(5701370..5702920) 1 NC_013093.1 PFAM: amidase; KEGG: bpt:Bpet1417 glutamyl-tRNA(Gln) amidotransferase subunit A; amidase 5702920 8328985 Amir_4787 Actinosynnema mirum DSM 43827 amidase YP_003102461.1 5701370 R 446462 CDS YP_003102462.1 256378802 8328986 5703027..5703911 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: rpt:Rpal_4911 beta-lactamase domain protein; beta-lactamase domain-containing protein 5703911 8328986 Amir_4788 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003102462.1 5703027 D 446462 CDS YP_003102463.1 256378803 8328987 5704118..5705599 1 NC_013093.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5705599 8328987 Amir_4789 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003102463.1 5704118 D 446462 CDS YP_003102464.1 256378804 8328988 complement(5705681..5706631) 1 NC_013093.1 KEGG: reh:H16_A1489 DNA topoisomerase IB; DNA topoisomerase IB 5706631 8328988 Amir_4790 Actinosynnema mirum DSM 43827 DNA topoisomerase IB YP_003102464.1 5705681 R 446462 CDS YP_003102465.1 256378805 8328989 complement(5706727..5707599) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pag:PLES_56121 transcriptional regulator; LysR family transcriptional regulator 5707599 8328989 Amir_4791 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102465.1 5706727 R 446462 CDS YP_003102466.1 256378806 8328990 5707723..5708448 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sus:Acid_6073 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 5708448 8328990 Amir_4792 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102466.1 5707723 D 446462 CDS YP_003102467.1 256378807 8328991 5708448..5709302 1 NC_013093.1 PFAM: amidohydrolase 2; KEGG: hypothetical protein; K07046; amidohydrolase 2 5709302 8328991 Amir_4793 Actinosynnema mirum DSM 43827 amidohydrolase 2 YP_003102467.1 5708448 D 446462 CDS YP_003102468.1 256378808 8328992 complement(5709312..5709875) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: ank:AnaeK_1572 regulatory protein TetR; TetR family transcriptional regulator 5709875 8328992 Amir_4794 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102468.1 5709312 R 446462 CDS YP_003102469.1 256378809 8328993 5709954..5710847 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: acp:A2cp1_1649 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 5710847 8328993 Amir_4795 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003102469.1 5709954 D 446462 CDS YP_003102470.1 256378810 8328994 5710939..5712210 1 NC_013093.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: par:Psyc_1255 TolB periplamsic protein; hypothetical protein 5712210 8328994 Amir_4796 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102470.1 5710939 D 446462 CDS YP_003102471.1 256378811 8328996 5712680..5712907 1 NC_013093.1 hypothetical protein 5712907 8328996 Amir_4798 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102471.1 5712680 D 446462 CDS YP_003102472.1 256378812 8328997 5712998..5714431 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: pde:Pden_3048 hypothetical protein; FAD-binding monooxygenase 5714431 8328997 Amir_4799 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102472.1 5712998 D 446462 CDS YP_003102473.1 256378813 8328998 complement(5714472..5717240) 1 NC_013093.1 PFAM: transcriptional regulator domain protein; transcriptional activator domain; KEGG: afw:Anae109_3667 ATPase-like protein; transcriptional regulator, winged helix family 5717240 8328998 Amir_4800 Actinosynnema mirum DSM 43827 transcriptional regulator, winged helix family YP_003102473.1 5714472 R 446462 CDS YP_003102474.1 256378814 8328999 complement(5717369..5718139) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: gdi:GDI1794 hypothetical protein; hypothetical protein 5718139 8328999 Amir_4801 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102474.1 5717369 R 446462 CDS YP_003102475.1 256378815 8329000 complement(5718169..5719695) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_1369 major facilitator superfamily MFS_1; major facilitator superfamily protein 5719695 8329000 Amir_4802 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102475.1 5718169 R 446462 CDS YP_003102476.1 256378816 8329001 5719816..5720397 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bac:BamMC406_5866 TetR family transcriptional regulator; TetR family transcriptional regulator 5720397 8329001 Amir_4803 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102476.1 5719816 D 446462 CDS YP_003102477.1 256378817 8329002 complement(5720384..5720989) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: sml:Smlt4073 TetR family regulatory protein; TetR family transcriptional regulator 5720989 8329002 Amir_4804 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102477.1 5720384 R 446462 CDS YP_003102478.1 256378818 8329003 complement(5721051..5721557) 1 NC_013093.1 KEGG: afw:Anae109_0991 major facilitator transporter; hypothetical protein 5721557 8329003 Amir_4805 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102478.1 5721051 R 446462 CDS YP_003102479.1 256378819 8329004 complement(5721662..5724019) 1 NC_013093.1 PFAM: coagulation factor 5/8 type domain protein; KEGG: hypothetical protein; coagulation factor 5/8 type domain-containing protein 5724019 8329004 Amir_4806 Actinosynnema mirum DSM 43827 coagulation factor 5/8 type domain-containing protein YP_003102479.1 5721662 R 446462 CDS YP_003102480.1 256378820 8329005 complement(5724121..5724600) 1 NC_013093.1 KEGG: mxa:MXAN_2741 hypothetical protein; hypothetical protein 5724600 8329005 Amir_4807 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102480.1 5724121 R 446462 CDS YP_003102481.1 256378821 8329006 complement(5724696..5725592) 1 NC_013093.1 KEGG: swi:Swit_3769 NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerase-like protein 5725592 8329006 Amir_4808 Actinosynnema mirum DSM 43827 Nucleoside-diphosphate-sugar epimerase-like protein YP_003102481.1 5724696 R 446462 CDS YP_003102482.1 256378822 8329007 complement(5725666..5726325) 1 NC_013093.1 PFAM: restriction endonuclease; KEGG: acr:Acry_3352 restriction endonuclease; restriction endonuclease 5726325 8329007 Amir_4809 Actinosynnema mirum DSM 43827 restriction endonuclease YP_003102482.1 5725666 R 446462 CDS YP_003102483.1 256378823 8329008 complement(5726704..5726976) 1 NC_013093.1 hypothetical protein 5726976 8329008 Amir_4810 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102483.1 5726704 R 446462 CDS YP_003102484.1 256378824 8329009 5727628..5730831 1 NC_013093.1 KEGG: pmy:Pmen_1048 signal transduction protein; signal transduction protein with Nacht domain 5730831 8329009 Amir_4811 Actinosynnema mirum DSM 43827 signal transduction protein with Nacht domain YP_003102484.1 5727628 D 446462 CDS YP_003102485.1 256378825 8329010 complement(5731126..5732466) 1 NC_013093.1 KEGG: mlo:mll6125 cytochrome P450-family protein; cytochrome P450-family protein 5732466 8329010 Amir_4812 Actinosynnema mirum DSM 43827 cytochrome P450-family protein YP_003102485.1 5731126 R 446462 CDS YP_003102486.1 256378826 8329011 complement(5732463..5733071) 1 NC_013093.1 PFAM: protein of unknown function ATP binding; KEGG: dac:Daci_0776 protein of unknown function ATP binding; hypothetical protein 5733071 8329011 Amir_4813 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102486.1 5732463 R 446462 CDS YP_003102487.1 256378827 8329012 complement(5733052..5733453) 1 NC_013093.1 PFAM: protein of unknown function DUF742; hypothetical protein 5733453 8329012 Amir_4814 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102487.1 5733052 R 446462 CDS YP_003102488.1 256378828 8329013 complement(5733450..5733869) 1 NC_013093.1 PFAM: Roadblock/LC7 family protein; Roadblock/LC7 family protein 5733869 8329013 Amir_4815 Actinosynnema mirum DSM 43827 Roadblock/LC7 family protein YP_003102488.1 5733450 R 446462 CDS YP_003102489.1 256378829 8329014 complement(5734002..5735894) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: hypothetical protein; ATP-binding region ATPase domain-containing protein 5735894 8329014 Amir_4816 Actinosynnema mirum DSM 43827 ATP-binding region ATPase domain-containing protein YP_003102489.1 5734002 R 446462 CDS YP_003102490.1 256378830 8329015 5736441..5737106 1 NC_013093.1 KEGG: ppw:PputW619_3130 hypothetical protein; hypothetical protein 5737106 8329015 Amir_4817 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102490.1 5736441 D 446462 CDS YP_003102491.1 256378831 8329016 complement(5737156..5738241) 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: atc:AGR_L_1778 hypothetical protein; oxidoreductase domain-containing protein 5738241 8329016 Amir_4818 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003102491.1 5737156 R 446462 CDS YP_003102492.1 256378832 8329017 complement(5738238..5738957) 1 NC_013093.1 PFAM: cupin; cupin 5738957 8329017 Amir_4819 Actinosynnema mirum DSM 43827 cupin YP_003102492.1 5738238 R 446462 CDS YP_003102493.1 256378833 8329018 complement(5738954..5739856) 1 NC_013093.1 KEGG: sus:Acid_2874 transmembrane prediction; hypothetical protein 5739856 8329018 Amir_4820 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102493.1 5738954 R 446462 CDS YP_003102494.1 256378834 8329019 5740013..5741146 1 NC_013093.1 KEGG: spe:Spro_1142 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase; glycerate kinase 5741146 8329019 Amir_4821 Actinosynnema mirum DSM 43827 glycerate kinase YP_003102494.1 5740013 D 446462 CDS YP_003102495.1 256378835 8329020 complement(5741267..5742052) 1 NC_013093.1 PFAM: xylose isomerase; KEGG: hypothetical protein; xylose isomerase 5742052 8329020 Amir_4822 Actinosynnema mirum DSM 43827 xylose isomerase YP_003102495.1 5741267 R 446462 CDS YP_003102496.1 256378836 8329021 5742161..5742889 1 NC_013093.1 KEGG: ilo:IL1495 hypothetical protein; hypothetical protein 5742889 8329021 Amir_4823 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102496.1 5742161 D 446462 CDS YP_003102497.1 256378837 8329022 complement(5742911..5743837) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pol:Bpro_4368 transcriptional regulator, LysR family; LysR family transcriptional regulator 5743837 8329022 Amir_4824 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102497.1 5742911 R 446462 CDS YP_003102498.1 256378838 8329023 5743899..5745239 1 NC_013093.1 PFAM: aminotransferase class-III; KEGG: bxe:Bxe_B2675 aminotransferase; class III aminotransferase 5745239 8329023 Amir_4825 Actinosynnema mirum DSM 43827 class III aminotransferase YP_003102498.1 5743899 D 446462 CDS YP_003102499.1 256378839 8329024 5745630..5746193 1 NC_013093.1 KEGG: rsq:Rsph17025_0144 chromosome segregation protein SMC; hypothetical protein 5746193 8329024 Amir_4826 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102499.1 5745630 D 446462 CDS YP_003102500.1 256378840 8329025 complement(5746691..5747029) 1 NC_013093.1 hypothetical protein 5747029 8329025 Amir_4827 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102500.1 5746691 R 446462 CDS YP_003102501.1 256378841 8329026 5747669..5749399 1 NC_013093.1 PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: bha:BH0494 exopolygalacturonate lyase; Ricin B lectin 5749399 8329026 Amir_4828 Actinosynnema mirum DSM 43827 Ricin B lectin YP_003102501.1 5747669 D 446462 CDS YP_003102502.1 256378842 8329027 complement(5749479..5749982) 1 NC_013093.1 hypothetical protein 5749982 8329027 Amir_4829 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102502.1 5749479 R 446462 CDS YP_003102503.1 256378843 8329028 complement(5750210..5750569) 1 NC_013093.1 KEGG: rfr:Rfer_3942 serine/threonine protein kinase with CHASE2 sensor; hypothetical protein 5750569 8329028 Amir_4830 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102503.1 5750210 R 446462 CDS YP_003102504.1 256378844 8329029 complement(5750918..5751523) 1 NC_013093.1 KEGG: YALI0B22110p; hypothetical protein 5751523 8329029 Amir_4831 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102504.1 5750918 R 446462 CDS YP_003102505.1 256378845 8329030 complement(5751527..5752615) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 5752615 8329030 Amir_4832 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102505.1 5751527 R 446462 CDS YP_003102506.1 256378846 8329031 complement(5753248..5753793) 1 NC_013093.1 PFAM: protein of unknown function DUF1697; KEGG: cak:Caul_2927 hypothetical protein; hypothetical protein 5753793 8329031 Amir_4833 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102506.1 5753248 R 446462 CDS YP_003102507.1 256378847 8329032 5754258..5755592 1 NC_013093.1 PFAM: cytochrome P450; KEGG: mxa:MXAN_2304 cytochrome P450 family protein; cytochrome P450 5755592 8329032 Amir_4834 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003102507.1 5754258 D 446462 CDS YP_003102508.1 256378848 8329033 5755642..5757402 1 NC_013093.1 KEGG: Eln; elastin; hypothetical protein 5757402 8329033 Amir_4835 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102508.1 5755642 D 446462 CDS YP_003102509.1 256378849 8329034 complement(5757488..5758222) 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: gbm:Gbem_1276 glycosyl transferase family 2; family 2 glycosyl transferase 5758222 8329034 Amir_4836 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003102509.1 5757488 R 446462 CDS YP_003102510.1 256378850 8329035 complement(5758355..5758945) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: msl:Msil_3313 transcriptional regulator, TetR family; TetR family transcriptional regulator 5758945 8329035 Amir_4837 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102510.1 5758355 R 446462 CDS YP_003102511.1 256378851 8329036 complement(5758972..5759886) 1 NC_013093.1 PFAM: NmrA family protein; KEGG: scl:sce0707 hypothetical protein; NmrA family protein 5759886 8329036 Amir_4838 Actinosynnema mirum DSM 43827 NmrA family protein YP_003102511.1 5758972 R 446462 CDS YP_003102512.1 256378852 8329037 5760076..5760786 1 NC_013093.1 KEGG: bcr:BCAH187_A3347 hypothetical protein; hypothetical protein 5760786 8329037 Amir_4839 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102512.1 5760076 D 446462 CDS YP_003102513.1 256378853 8329038 complement(5760929..5761150) 1 NC_013093.1 hypothetical protein 5761150 8329038 Amir_4840 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102513.1 5760929 R 446462 CDS YP_003102514.1 256378854 8329039 complement(5761240..5762571) 1 NC_013093.1 PFAM: glycosyl transferase family 28; KEGG: afw:Anae109_0485 glycosyl transferase family protein; Sterol 3-beta-glucosyltransferase 5762571 8329039 Amir_4841 Actinosynnema mirum DSM 43827 Sterol 3-beta-glucosyltransferase YP_003102514.1 5761240 R 446462 CDS YP_003102515.1 256378855 8329040 complement(5762568..5764670) 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: scl:sce8590 prolyl oligopeptidase; peptidase S9 prolyl oligopeptidase active site domain-containing protein 5764670 8329040 Amir_4842 Actinosynnema mirum DSM 43827 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_003102515.1 5762568 R 446462 CDS YP_003102516.1 256378856 8329041 complement(5764674..5765699) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; short- chain dehydrogenase/reductase SDR; KEGG: ppd:Ppro_3571 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 5765699 8329041 Amir_4843 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003102516.1 5764674 R 446462 CDS YP_003102517.1 256378857 8329042 complement(5765696..5767000) 1 NC_013093.1 PFAM: glycosyl transferase family 28; KEGG: afw:Anae109_0485 glycosyl transferase family protein; Sterol 3-beta-glucosyltransferase 5767000 8329042 Amir_4844 Actinosynnema mirum DSM 43827 Sterol 3-beta-glucosyltransferase YP_003102517.1 5765696 R 446462 CDS YP_003102518.1 256378858 8329043 complement(5767060..5768277) 1 NC_013093.1 PFAM: cytochrome P450; KEGG: scl:sce8913 cytochrome P450 CYP109C2; cytochrome P450 5768277 8329043 Amir_4845 Actinosynnema mirum DSM 43827 cytochrome P450 YP_003102518.1 5767060 R 446462 CDS YP_003102519.1 256378859 8329044 complement(5768374..5768466) 1 NC_013093.1 hypothetical protein 5768466 8329044 Amir_4846 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102519.1 5768374 R 446462 CDS YP_003102520.1 256378860 8329045 complement(5768520..5768618) 1 NC_013093.1 hypothetical protein 5768618 8329045 Amir_4847 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102520.1 5768520 R 446462 CDS YP_003102521.1 256378861 8329046 complement(5768650..5771292) 1 NC_013093.1 PFAM: lanthionine synthetase C family protein; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; KEGG: smt:Smal_2130 serine/threonine protein kinase; serine/threonine protein kinase 5771292 8329046 Amir_4848 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003102521.1 5768650 R 446462 CDS YP_003102522.1 256378862 8329047 complement(5771450..5772061) 1 NC_013093.1 PFAM: flavoprotein; KEGG: tgr:Tgr7_0102 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; flavoprotein 5772061 8329047 Amir_4849 Actinosynnema mirum DSM 43827 flavoprotein YP_003102522.1 5771450 R 446462 CDS YP_003102523.1 256378863 8329048 complement(5772058..5772672) 1 NC_013093.1 PFAM: MaoC domain protein dehydratase; KEGG: reu:Reut_A1571 MaoC-like dehydratase; MaoC domain-containing protein dehydratase 5772672 8329048 Amir_4850 Actinosynnema mirum DSM 43827 MaoC domain-containing protein dehydratase YP_003102523.1 5772058 R 446462 CDS YP_003102524.1 256378864 8329049 complement(5772677..5773441) 1 NC_013093.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 5773441 8329049 Amir_4851 Actinosynnema mirum DSM 43827 enoyl-(acyl carrier protein) reductase YP_003102524.1 5772677 R 446462 CDS YP_003102525.1 256378865 8329050 complement(5773446..5774150) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: tbd:Tbd_1549 3-oxoacyl-[acyl-carrier-protein] reductase; short-chain dehydrogenase/reductase SDR 5774150 8329050 Amir_4852 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102525.1 5773446 R 446462 CDS YP_003102526.1 256378866 8329051 complement(5774147..5779606) 1 NC_013093.1 PFAM: acyl transferase; beta-ketoacyl synthase; KR domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_4528 polyketide synthase; acyl transferase 5779606 8329051 Amir_4853 Actinosynnema mirum DSM 43827 acyl transferase YP_003102526.1 5774147 R 446462 CDS YP_003102527.1 256378867 8329053 5780990..5781487 1 NC_013093.1 KEGG: gox:GOX1622 transposase; hypothetical protein 5781487 8329053 Amir_4855 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102527.1 5780990 D 446462 CDS YP_003102528.1 256378868 8329054 5781695..5783101 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: bvi:Bcep1808_2651 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 5783101 8329054 Amir_4856 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102528.1 5781695 D 446462 CDS YP_003102529.1 256378869 8329055 5783098..5784357 1 NC_013093.1 TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: beta-ketoacyl synthase; KEGG: mgm:Mmc1_1872 3-oxoacyl-[acyl-carrier- protein] synthase II; 3-oxoacyl-(acyl-carrier-protein) synthase 2 5784357 8329055 Amir_4857 Actinosynnema mirum DSM 43827 3-oxoacyl-(acyl-carrier-protein) synthase 2 YP_003102529.1 5783098 D 446462 CDS YP_003102530.1 256378870 8329056 5784400..5785698 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: plu:plu3928 hypothetical protein; aldehyde dehydrogenase 5785698 8329056 Amir_4858 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003102530.1 5784400 D 446462 CDS YP_003102531.1 256378871 8329057 5785695..5787365 1 NC_013093.1 PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: eba:ebA4751 acetolactate synthase catalytic subunit; thiamine pyrophosphate protein 5787365 8329057 Amir_4859 Actinosynnema mirum DSM 43827 thiamine pyrophosphate protein YP_003102531.1 5785695 D 446462 CDS YP_003102532.1 256378872 8329058 5787362..5789110 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce8262 non-ribosomal peptide synthetase; AMP-dependent synthetase and ligase 5789110 8329058 Amir_4860 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003102532.1 5787362 D 446462 CDS YP_003102533.1 256378873 8329059 5789149..5789406 1 NC_013093.1 PFAM: phosphopantetheine-binding; KEGG: pcr:Pcryo_0517 acyl carrier protein; phosphopantetheine-binding 5789406 8329059 Amir_4861 Actinosynnema mirum DSM 43827 phosphopantetheine-binding YP_003102533.1 5789149 D 446462 CDS YP_003102534.1 256378874 8329060 complement(5789471..5791270) 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: bsu:BSU34820 hypothetical protein; ABC transporter 5791270 8329060 Amir_4862 Actinosynnema mirum DSM 43827 ABC transporter YP_003102534.1 5789471 R 446462 CDS YP_003102535.1 256378875 8329061 5791317..5791940 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bha:BH2103 hypothetical protein; TetR family transcriptional regulator 5791940 8329061 Amir_4863 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102535.1 5791317 D 446462 CDS YP_003102536.1 256378876 8329062 complement(5791961..5794018) 1 NC_013093.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bxe:Bxe_B1779 major facilitator superfamily multidrug efflux transporter; EmrB/QacA subfamily drug resistance transporter 5794018 8329062 Amir_4864 Actinosynnema mirum DSM 43827 EmrB/QacA subfamily drug resistance transporter YP_003102536.1 5791961 R 446462 CDS YP_003102537.1 256378877 8329063 complement(5794273..5795706) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bmv:BMASAVP1_0279 EmrB/QacA family drug resistance transporter; major facilitator superfamily protein 5795706 8329063 Amir_4865 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102537.1 5794273 R 446462 CDS YP_003102538.1 256378878 8329064 complement(5795703..5797235) 1 NC_013093.1 PFAM: NHL repeat containing protein; KEGG: bxe:Bxe_C0275 hypothetical protein; NHL repeat containing protein 5797235 8329064 Amir_4866 Actinosynnema mirum DSM 43827 NHL repeat containing protein YP_003102538.1 5795703 R 446462 CDS YP_003102539.1 256378879 8329065 complement(5797232..5799193) 1 NC_013093.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pzu:PHZ_c1832 monooxygenase; cyclohexanone monooxygenase 5799193 8329065 Amir_4867 Actinosynnema mirum DSM 43827 cyclohexanone monooxygenase YP_003102539.1 5797232 R 446462 CDS YP_003102540.1 256378880 8329066 5799287..5799661 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: kpe:KPK_1169 DNA-binding protein; XRE family transcriptional regulator 5799661 8329066 Amir_4868 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102540.1 5799287 D 446462 CDS YP_003102541.1 256378881 8329067 complement(5799746..5806618) 1 NC_013093.1 TIGRFAM: YD repeat protein; SMART: Hedgehog/intein hint domain protein; KEGG: dal:Dalk_1487 YD repeat protein; YD repeat-containing protein 5806618 8329067 Amir_4869 Actinosynnema mirum DSM 43827 YD repeat-containing protein YP_003102541.1 5799746 R 446462 CDS YP_003102542.1 256378882 8329068 complement(5806663..5810106) 1 NC_013093.1 SMART: LamG domain protein jellyroll fold domain protein; KEGG: bat:BAS1022 wall-associated protein; LamG domain-containing protein 5810106 8329068 Amir_4870 Actinosynnema mirum DSM 43827 LamG domain-containing protein YP_003102542.1 5806663 R 446462 CDS YP_003102543.1 256378883 8329069 complement(5810478..5810864) 1 NC_013093.1 hypothetical protein 5810864 8329069 Amir_4871 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102543.1 5810478 R 446462 CDS YP_003102544.1 256378884 8329070 complement(5810924..5813152) 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: glycoside hydrolase, family 3, N- terminal:glycoside hydrolase, family 3, C-terminal; glycoside hydrolase family protein 5813152 8329070 Amir_4872 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003102544.1 5810924 R 446462 CDS YP_003102545.1 256378885 8329071 5813249..5813830 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: psb:Psyr_3154 regulatory protein, TetR; TetR family transcriptional regulator 5813830 8329071 Amir_4873 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102545.1 5813249 D 446462 CDS YP_003102546.1 256378886 8329072 complement(5813832..5814254) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rlt:Rleg2_6394 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 5814254 8329072 Amir_4874 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003102546.1 5813832 R 446462 CDS YP_003102547.1 256378887 8329073 complement(5814319..5814594) 1 NC_013093.1 hypothetical protein 5814594 8329073 Amir_4875 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102547.1 5814319 R 446462 CDS YP_003102548.1 256378888 8329074 5814623..5814745 1 NC_013093.1 hypothetical protein 5814745 8329074 Amir_4876 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102548.1 5814623 D 446462 CDS YP_003102549.1 256378889 8329075 5814878..5817448 1 NC_013093.1 SMART: ATPase AAA; KEGG: mxa:MXAN_4188 adenylate/guanylate cyclase domain protein; ATPase AAA 5817448 8329075 Amir_4877 Actinosynnema mirum DSM 43827 ATPase AAA YP_003102549.1 5814878 D 446462 CDS YP_003102550.1 256378890 8329076 complement(5817461..5818051) 1 NC_013093.1 hypothetical protein 5818051 8329076 Amir_4878 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102550.1 5817461 R 446462 CDS YP_003102551.1 256378891 8329077 complement(5818246..5819628) 1 NC_013093.1 KEGG: mxa:MXAN_2888 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Coproporphyrinogen dehydrogenase 5819628 8329077 Amir_4879 Actinosynnema mirum DSM 43827 Coproporphyrinogen dehydrogenase YP_003102551.1 5818246 R 446462 CDS YP_003102552.1 256378892 8329078 complement(5819649..5820002) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: mxa:MXAN_3769 hydrolase, NUDIX family; NUDIX hydrolase 5820002 8329078 Amir_4880 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003102552.1 5819649 R 446462 CDS YP_003102553.1 256378893 8329079 5820276..5820926 1 NC_013093.1 KEGG: pla:Plav_1718 shikimate kinase; hypothetical protein 5820926 8329079 Amir_4881 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102553.1 5820276 D 446462 CDS YP_003102554.1 256378894 8329080 5821126..5822457 1 NC_013093.1 PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: dal:Dalk_4445 peptidase M20; hypothetical protein 5822457 8329080 Amir_4882 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102554.1 5821126 D 446462 CDS YP_003102555.1 256378895 8329081 5822599..5823291 1 NC_013093.1 hypothetical protein 5823291 8329081 Amir_4883 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102555.1 5822599 D 446462 CDS YP_003102556.1 256378896 8329082 complement(5823448..5824230) 1 NC_013093.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: sus:Acid_3105 IclR family transcriptional regulator; IclR family transcriptional regulator 5824230 8329082 Amir_4884 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003102556.1 5823448 R 446462 CDS YP_003102557.1 256378897 8329083 complement(5824290..5825072) 1 NC_013093.1 PFAM: purine or other phosphorylase family 1; KEGG: aha:AHA_3168 uridine phosphorylase; purine or other phosphorylase family 1 5825072 8329083 Amir_4885 Actinosynnema mirum DSM 43827 purine or other phosphorylase family 1 YP_003102557.1 5824290 R 446462 CDS YP_003102558.1 256378898 8329084 5825271..5826164 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sat:SYN_00367 sulfate transport ATP-binding protein; ABC transporter 5826164 8329084 Amir_4886 Actinosynnema mirum DSM 43827 ABC transporter YP_003102558.1 5825271 D 446462 CDS YP_003102559.1 256378899 8329085 5826161..5826964 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bav:BAV0644 ABC transporter, permease protein; ABC transporter inner membrane protein 5826964 8329085 Amir_4887 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102559.1 5826161 D 446462 CDS YP_003102560.1 256378900 8329086 5827032..5828063 1 NC_013093.1 PFAM: NMT1/THI5 like domain protein; SMART: extracellular solute-binding protein family 3; KEGG: mes:Meso_0815 sulfonate transport system substrate-binding protein; NMT1/THI5 like domain-containing protein 5828063 8329086 Amir_4888 Actinosynnema mirum DSM 43827 NMT1/THI5 like domain-containing protein YP_003102560.1 5827032 D 446462 CDS YP_003102561.1 256378901 8329087 5828060..5828836 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_1169 ABC transporter permease protein; ABC transporter inner membrane protein 5828836 8329087 Amir_4889 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102561.1 5828060 D 446462 CDS YP_003102562.1 256378902 8329088 5829168..5829638 1 NC_013093.1 KEGG: type I polyketide synthase; K09936 hypothetical protein; type I polyketide synthase 5829638 8329088 Amir_4890 Actinosynnema mirum DSM 43827 type I polyketide synthase YP_003102562.1 5829168 D 446462 CDS YP_003102563.1 256378903 8329089 5829982..5831325 1 NC_013093.1 TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: scl:sce4269 dihydroorotase; dihydroorotase, multifunctional complex type 5831325 8329089 Amir_4891 Actinosynnema mirum DSM 43827 dihydroorotase, multifunctional complex type YP_003102563.1 5829982 D 446462 CDS YP_003102564.1 256378904 8329090 complement(5831395..5832351) 1 NC_013093.1 PFAM: Kelch repeat-containing protein; Kelch repeat protein; SMART: Kelch repeat-containing protein; KEGG: mex:Mext_0574 kelch repeat-containing protein; Kelch repeat-containing protein 5832351 8329090 Amir_4892 Actinosynnema mirum DSM 43827 Kelch repeat-containing protein YP_003102564.1 5831395 R 446462 CDS YP_003102565.1 256378905 8329091 5832435..5833277 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; LysR family transcriptional regulator 5833277 8329091 Amir_4893 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102565.1 5832435 D 446462 CDS YP_003102566.1 256378906 8329092 5833474..5835150 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: scl:sce5237 protein kinase; serine/threonine protein kinase 5835150 8329092 Amir_4894 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003102566.1 5833474 D 446462 CDS YP_003102567.1 256378907 8329093 5835680..5835904 1 NC_013093.1 hypothetical protein 5835904 8329093 Amir_4895 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102567.1 5835680 D 446462 CDS YP_003102568.1 256378908 8329094 complement(5836268..5837341) 1 NC_013093.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bam:Bamb_4722 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 5837341 8329094 Amir_4896 Actinosynnema mirum DSM 43827 NADH:flavin oxidoreductase/NADH oxidase YP_003102568.1 5836268 R 446462 CDS YP_003102569.1 256378909 8329095 5837497..5837952 1 NC_013093.1 PFAM: regulatory protein MarR; regulatory protein ArsR; SMART: regulatory protein MarR; KEGG: azc:AZC_0116 regulatory protein; MarR family transcriptional regulator 5837952 8329095 Amir_4897 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003102569.1 5837497 D 446462 CDS YP_003102570.1 256378910 8329096 5838111..5838470 1 NC_013093.1 KEGG: bsu:BSU26920 hypothetical protein; hypothetical protein 5838470 8329096 Amir_4898 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102570.1 5838111 D 446462 CDS YP_003102571.1 256378911 8329097 complement(5838516..5838890) 1 NC_013093.1 hypothetical protein 5838890 8329097 Amir_4899 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102571.1 5838516 R 446462 CDS YP_003102572.1 256378912 8329098 5839320..5839988 1 NC_013093.1 KEGG: bce:BC3289 hypothetical protein; hypothetical protein 5839988 8329098 Amir_4900 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102572.1 5839320 D 446462 CDS YP_003102573.1 256378913 8329099 5840182..5840667 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: reu:Reut_A1539 LuxR family transcriptional regulator; LuxR family transcriptional regulator 5840667 8329099 Amir_4901 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102573.1 5840182 D 446462 CDS YP_003102574.1 256378914 8329100 complement(5840759..5841199) 1 NC_013093.1 hypothetical protein 5841199 8329100 Amir_4902 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102574.1 5840759 R 446462 CDS YP_003102575.1 256378915 8329101 complement(5841304..5842035) 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: jan:Jann_4133 GntR family transcriptional regulator; GntR family transcriptional regulator 5842035 8329101 Amir_4903 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003102575.1 5841304 R 446462 CDS YP_003102576.1 256378916 8329102 complement(5842070..5842849) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: rsq:Rsph17025_3334 hypothetical protein; ABC transporter 5842849 8329102 Amir_4904 Actinosynnema mirum DSM 43827 ABC transporter YP_003102576.1 5842070 R 446462 CDS YP_003102577.1 256378917 8329103 complement(5842846..5843895) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: dac:Daci_3152 transport system permease protein; transport system permease 5843895 8329103 Amir_4905 Actinosynnema mirum DSM 43827 transport system permease YP_003102577.1 5842846 R 446462 CDS YP_003102578.1 256378918 8329104 complement(5843892..5844974) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: atc:AGR_pAT_449 ferric enterobactin transport protein FepD; transport system permease 5844974 8329104 Amir_4906 Actinosynnema mirum DSM 43827 transport system permease YP_003102578.1 5843892 R 446462 CDS YP_003102579.1 256378919 8329105 complement(5844974..5845930) 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: bsu:BSU08440 hypothetical protein; periplasmic binding protein 5845930 8329105 Amir_4907 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003102579.1 5844974 R 446462 CDS YP_003102580.1 256378920 8329106 complement(5846003..5847709) 1 NC_013093.1 KEGG: mxa:MXAN_2857 lantibiotic modification protein; lantibiotic modification protein 5847709 8329106 Amir_4908 Actinosynnema mirum DSM 43827 lantibiotic modification protein YP_003102580.1 5846003 R 446462 CDS YP_003102581.1 256378921 8329107 complement(5847706..5848596) 1 NC_013093.1 PFAM: aminotransferase class IV; KEGG: afw:Anae109_1102 branched-chain amino acid aminotransferase; class IV aminotransferase 5848596 8329107 Amir_4909 Actinosynnema mirum DSM 43827 class IV aminotransferase YP_003102581.1 5847706 R 446462 CDS YP_003102582.1 256378922 8329108 complement(5848593..5849711) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: mxa:MXAN_4001 non-ribosomal peptide synthase/polyketide synthase; luciferase-like monooxygenase 5849711 8329108 Amir_4910 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003102582.1 5848593 R 446462 CDS YP_003102583.1 256378923 8329109 complement(5849711..5854111) 1 NC_013093.1 PFAM: beta-ketoacyl synthase; KR domain protein; acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3620 polyketide synthase type I; beta-ketoacyl synthase 5854111 8329109 Amir_4911 Actinosynnema mirum DSM 43827 beta-ketoacyl synthase YP_003102583.1 5849711 R 446462 CDS YP_003102584.1 256378924 8329110 complement(5854108..5859255) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein 5859255 8329110 Amir_4912 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102584.1 5854108 R 446462 CDS YP_003102585.1 256378925 8329111 complement(5859252..5861474) 1 NC_013093.1 PFAM: peptidase S45 penicillin amidase; KEGG: scl:sce8259 penicillin amidase; peptidase S45 penicillin amidase 5861474 8329111 Amir_4913 Actinosynnema mirum DSM 43827 peptidase S45 penicillin amidase YP_003102585.1 5859252 R 446462 CDS YP_003102586.1 256378926 8329112 complement(5861467..5862804) 1 NC_013093.1 PFAM: condensation domain protein; KEGG: mxa:MXAN_4525 non-ribosomal peptide synthase MxaA; condensation domain-containing protein 5862804 8329112 Amir_4914 Actinosynnema mirum DSM 43827 condensation domain-containing protein YP_003102586.1 5861467 R 446462 CDS YP_003102587.1 256378927 8329113 complement(5862801..5863847) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: hypothetical protein; aldo/keto reductase 5863847 8329113 Amir_4915 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003102587.1 5862801 R 446462 CDS YP_003102588.1 256378928 8329114 complement(5863840..5865111) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bpy:Bphyt_3134 major facilitator superfamily MFS_1; major facilitator superfamily protein 5865111 8329114 Amir_4916 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102588.1 5863840 R 446462 CDS YP_003102589.1 256378929 8329115 complement(5865169..5865267) 1 NC_013093.1 hypothetical protein 5865267 8329115 Amir_4917 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102589.1 5865169 R 446462 CDS YP_003102590.1 256378930 8329116 5865719..5866492 1 NC_013093.1 PFAM: thiazole biosynthesis family protein; KEGG: esa:ESA_03683 thiazole synthase; thiazole biosynthesis family protein 5866492 8329116 Amir_4918 Actinosynnema mirum DSM 43827 thiazole biosynthesis family protein YP_003102590.1 5865719 D 446462 CDS YP_003102591.1 256378931 8329117 complement(5866938..5867300) 1 NC_013093.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist 5867300 8329117 Amir_4919 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003102591.1 5866938 R 446462 CDS YP_003102592.1 256378932 8329118 complement(5867297..5868397) 1 NC_013093.1 PFAM: cobalamin B12-binding domain protein; KEGG: rpc:RPC_1467 cobalamin B12-binding; cobalamin B12-binding domain-containing protein 5868397 8329118 Amir_4920 Actinosynnema mirum DSM 43827 cobalamin B12-binding domain-containing protein YP_003102592.1 5867297 R 446462 CDS YP_003102593.1 256378933 8329119 complement(5868394..5870043) 1 NC_013093.1 PFAM: Stage II sporulation E family protein; GAF domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; KEGG: sus:Acid_6601 serine phosphatase; protein serine phosphatase with GAF(s) sensor(s) 5870043 8329119 Amir_4921 Actinosynnema mirum DSM 43827 protein serine phosphatase with GAF(s) sensor(s) YP_003102593.1 5868394 R 446462 CDS YP_003102594.1 256378934 8329120 complement(5870336..5870731) 1 NC_013093.1 KEGG: rsq:Rsph17025_3833 hypothetical protein; hypothetical protein 5870731 8329120 Amir_4922 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102594.1 5870336 R 446462 CDS YP_003102595.1 256378935 8329121 complement(5870927..5871964) 1 NC_013093.1 KEGG: nar:Saro_3082 protein tyrosine/serine phosphatase; protein tyrosine/serine phosphatase 5871964 8329121 Amir_4923 Actinosynnema mirum DSM 43827 protein tyrosine/serine phosphatase YP_003102595.1 5870927 R 446462 CDS YP_003102596.1 256378936 8329122 complement(5871973..5873988) 1 NC_013093.1 KEGG: mxa:MXAN_6381 hypothetical protein; hypothetical protein 5873988 8329122 Amir_4924 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102596.1 5871973 R 446462 CDS YP_003102597.1 256378937 8329123 complement(5873990..5874877) 1 NC_013093.1 KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein 5874877 8329123 Amir_4925 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102597.1 5873990 R 446462 CDS YP_003102598.1 256378938 8329124 5875296..5876483 1 NC_013093.1 KEGG: bxe:Bxe_B2117 CdaR family transcriptional regulator; CdaR family transcriptional regulator 5876483 8329124 Amir_4926 Actinosynnema mirum DSM 43827 CdaR family transcriptional regulator YP_003102598.1 5875296 D 446462 CDS YP_003102599.1 256378939 8329125 5876641..5878128 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1549 ABC transporter substrate-binding protein; family 5 extracellular solute-binding protein 5878128 8329125 Amir_4927 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003102599.1 5876641 D 446462 CDS YP_003102600.1 256378940 8329126 5878163..5879878 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_2742 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 5879878 8329126 Amir_4928 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102600.1 5878163 D 446462 CDS YP_003102601.1 256378941 8329127 5879879..5881066 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_3208 major facilitator transporter; major facilitator superfamily protein 5881066 8329127 Amir_4929 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102601.1 5879879 D 446462 CDS YP_003102602.1 256378942 8329128 complement(5881105..5882268) 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: bvi:Bcep1808_6371 transcriptional regulator; helix-turn-helix domain-containing protein 5882268 8329128 Amir_4930 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003102602.1 5881105 R 446462 CDS YP_003102603.1 256378943 8329129 5882507..5883967 1 NC_013093.1 PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: pde:Pden_4560 sodium/sulphate symporter; sodium/sulfate symporter 5883967 8329129 Amir_4931 Actinosynnema mirum DSM 43827 sodium/sulfate symporter YP_003102603.1 5882507 D 446462 CDS YP_003102604.1 256378944 8329130 5883986..5885137 1 NC_013093.1 KEGG: pde:Pden_4561 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase; glycerate kinase 5885137 8329130 Amir_4932 Actinosynnema mirum DSM 43827 glycerate kinase YP_003102604.1 5883986 D 446462 CDS YP_003102605.1 256378945 8329131 5885217..5885537 1 NC_013093.1 KEGG: scl:sce2447 transcriptional regulator; transcriptional regulator 5885537 8329131 Amir_4933 Actinosynnema mirum DSM 43827 transcriptional regulator YP_003102605.1 5885217 D 446462 CDS YP_003102606.1 256378946 8329132 5885573..5887120 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase 5887120 8329132 Amir_4934 Actinosynnema mirum DSM 43827 histidine kinase YP_003102606.1 5885573 D 446462 CDS YP_003102607.1 256378947 8329133 5887105..5887770 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: two component heavy metal response transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 5887770 8329133 Amir_4935 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003102607.1 5887105 D 446462 CDS YP_003102608.1 256378948 8329134 5888249..5889085 1 NC_013093.1 PFAM: lytic transglycosylase catalytic; KEGG: bsu:BSU26030 hypothetical protein; lytic transglycosylase 5889085 8329134 Amir_4936 Actinosynnema mirum DSM 43827 lytic transglycosylase YP_003102608.1 5888249 D 446462 CDS YP_003102609.1 256378949 8329135 5889386..5890978 1 NC_013093.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: rpe:RPE_0181 Na+/H+ antiporter; Na+/H+ antiporter 5890978 8329135 Amir_4937 Actinosynnema mirum DSM 43827 Na+/H+ antiporter YP_003102609.1 5889386 D 446462 CDS YP_003102610.1 256378950 8329136 complement(5890985..5892421) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_1465 major facilitator transporter; major facilitator superfamily protein 5892421 8329136 Amir_4938 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102610.1 5890985 R 446462 CDS YP_003102611.1 256378951 8329137 complement(5892418..5893296) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: bvi:Bcep1808_3804 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 5893296 8329137 Amir_4939 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003102611.1 5892418 R 446462 CDS YP_003102612.1 256378952 8329138 5893330..5894262 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; LysR family transcriptional regulator 5894262 8329138 Amir_4940 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102612.1 5893330 D 446462 CDS YP_003102613.1 256378953 8329139 5894326..5894721 1 NC_013093.1 hypothetical protein 5894721 8329139 Amir_4941 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102613.1 5894326 D 446462 CDS YP_003102614.1 256378954 8329140 5894806..5895813 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: short-chain dehydrogenase/reductase (SDR) family protein; short-chain dehydrogenase/reductase SDR 5895813 8329140 Amir_4942 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102614.1 5894806 D 446462 CDS YP_003102615.1 256378955 8329141 complement(5895901..5896632) 1 NC_013093.1 PFAM: survival protein SurE; KEGG: rce:RC1_0808 5'/3'-nucleotidase SurE; survival protein SurE 5896632 8329141 Amir_4943 Actinosynnema mirum DSM 43827 survival protein SurE YP_003102615.1 5895901 R 446462 CDS YP_003102616.1 256378956 8329142 complement(5896629..5897543) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: bha:BH0827 fructose 1-phosphate kinase; PfkB domain-containing protein 5897543 8329142 Amir_4944 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003102616.1 5896629 R 446462 CDS YP_003102617.1 256378957 8329143 complement(5897661..5899031) 1 NC_013093.1 KEGG: scl:sce9313 hypothetical protein; hypothetical protein 5899031 8329143 Amir_4945 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102617.1 5897661 R 446462 CDS YP_003102618.1 256378958 8329144 5899252..5900142 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 5900142 8329144 Amir_4946 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102618.1 5899252 D 446462 CDS YP_003102619.1 256378959 8329145 complement(5900186..5901841) 1 NC_013093.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: hypothetical protein; amine oxidase 5901841 8329145 Amir_4947 Actinosynnema mirum DSM 43827 amine oxidase YP_003102619.1 5900186 R 446462 CDS YP_003102620.1 256378960 8329146 5901951..5902766 1 NC_013093.1 KEGG: bid:Bind_2275 membrane protein-like protein; hypothetical protein 5902766 8329146 Amir_4948 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102620.1 5901951 D 446462 CDS YP_003102621.1 256378961 8329147 5902763..5903920 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_3434 glycosyl transferase family protein; family 2 glycosyl transferase 5903920 8329147 Amir_4949 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003102621.1 5902763 D 446462 CDS YP_003102622.1 256378962 8329148 complement(5903864..5904598) 1 NC_013093.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: ank:AnaeK_2943 CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase 5904598 8329148 Amir_4950 Actinosynnema mirum DSM 43827 CDP-alcohol phosphatidyltransferase YP_003102622.1 5903864 R 446462 CDS YP_003102623.1 256378963 8329149 5905661..5906506 1 NC_013093.1 KEGG: dsh:Dshi_1005 ribonuclease BN; hypothetical protein 5906506 8329149 Amir_4951 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102623.1 5905661 D 446462 CDS YP_003102624.1 256378964 8329150 5906591..5907799 1 NC_013093.1 KEGG: mxa:MXAN_1566 hypothetical protein; hypothetical protein 5907799 8329150 Amir_4952 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102624.1 5906591 D 446462 CDS YP_003102625.1 256378965 8329151 5908004..5908942 1 NC_013093.1 PFAM: peptidase M28; peptidase M20; KEGG: pap:PSPA7_2223 aminopeptidase; aminopeptidase 5908942 8329151 Amir_4953 Actinosynnema mirum DSM 43827 aminopeptidase YP_003102625.1 5908004 D 446462 CDS YP_003102626.1 256378966 8329152 complement(5908946..5909863) 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: psb:Psyr_1799 hypothetical protein; hypothetical protein 5909863 8329152 Amir_4954 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102626.1 5908946 R 446462 CDS YP_003102627.1 256378967 8329153 5909924..5910580 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bxe:Bxe_B3018 TetR family transcriptional regulator; TetR family transcriptional regulator 5910580 8329153 Amir_4955 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102627.1 5909924 D 446462 CDS YP_003102628.1 256378968 8329154 5910899..5911636 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: aba:Acid345_0505 glycosyl transferase, family 2; family 2 glycosyl transferase 5911636 8329154 Amir_4956 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003102628.1 5910899 D 446462 CDS YP_003102629.1 256378969 8329155 5911633..5913189 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: afw:Anae109_1425 glycosyl transferase group 1; group 1 glycosyl transferase 5913189 8329155 Amir_4957 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003102629.1 5911633 D 446462 CDS YP_003102630.1 256378970 8329156 5913243..5915711 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: ade:Adeh_3504 phosphatidylinositol alpha- mannosyltransferase; group 1 glycosyl transferase 5915711 8329156 Amir_4958 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003102630.1 5913243 D 446462 CDS YP_003102631.1 256378971 8329157 5915708..5917198 1 NC_013093.1 KEGG: tgr:Tgr7_3096 glycosyl transferase family 39; hypothetical protein 5917198 8329157 Amir_4959 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102631.1 5915708 D 446462 CDS YP_003102632.1 256378972 8329158 5917195..5918349 1 NC_013093.1 PFAM: acyltransferase 3; KEGG: cak:Caul_2329 acyltransferase 3; acyltransferase 3 5918349 8329158 Amir_4960 Actinosynnema mirum DSM 43827 acyltransferase 3 YP_003102632.1 5917195 D 446462 CDS YP_003102633.1 256378973 8329159 complement(5918378..5919166) 1 NC_013093.1 KEGG: dal:Dalk_1860 hypothetical protein; hypothetical protein 5919166 8329159 Amir_4961 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102633.1 5918378 R 446462 CDS YP_003102634.1 256378974 8329160 complement(5919163..5919753) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rme:Rmet_4903 transcriptional regulator, TetR family; TetR family transcriptional regulator 5919753 8329160 Amir_4962 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102634.1 5919163 R 446462 CDS YP_003102635.1 256378975 8329161 complement(5919904..5922537) 1 NC_013093.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: rfr:Rfer_1113 glycoside hydrolase family protein; glycoside hydrolase family protein 5922537 8329161 Amir_4963 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003102635.1 5919904 R 446462 CDS YP_003102636.1 256378976 8329162 complement(5922777..5925161) 1 NC_013093.1 PFAM: pectinesterase; Ricin B lectin; pectate lyase/Amb allergen; SMART: Ricin B lectin; Parallel beta-helix repeat; pectate lyase/Amb allergen; KEGG: bha:BH0698 pectate lyase; pectinesterase 5925161 8329162 Amir_4964 Actinosynnema mirum DSM 43827 pectinesterase YP_003102636.1 5922777 R 446462 CDS YP_003102637.1 256378977 8329163 5925378..5926304 1 NC_013093.1 KEGG: pip; proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; proline iminopeptidase 5926304 8329163 Amir_4965 Actinosynnema mirum DSM 43827 proline iminopeptidase YP_003102637.1 5925378 D 446462 CDS YP_003102638.1 256378978 8329164 complement(5926380..5927903) 1 NC_013093.1 KEGG: hypothetical protein; PFAM: glycoside hydrolase family 62; Ricin B lectin; SMART: Ricin B lectin; alpha-N-arabinofuranosidase 5927903 8329164 Amir_4966 Actinosynnema mirum DSM 43827 alpha-N-arabinofuranosidase YP_003102638.1 5926380 R 446462 CDS YP_003102639.1 256378979 8329165 complement(5928141..5928362) 1 NC_013093.1 hypothetical protein 5928362 8329165 Amir_4967 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102639.1 5928141 R 446462 CDS YP_003102640.1 256378980 8329166 complement(5928359..5928478) 1 NC_013093.1 hypothetical protein 5928478 8329166 Amir_4968 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102640.1 5928359 R 446462 CDS YP_003102641.1 256378981 8329167 5928734..5929717 1 NC_013093.1 KEGG: acr:Acry_0972 methionyl-tRNA synthetase; methionyl-tRNA synthetase-like protein 5929717 8329167 Amir_4969 Actinosynnema mirum DSM 43827 methionyl-tRNA synthetase-like protein YP_003102641.1 5928734 D 446462 CDS YP_003102642.1 256378982 8329168 complement(5929742..5930332) 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; Tellurite resistance methyltransferase, TehB, core; thiopurine S-methyltransferase; KEGG: scl:sce2146 methyltransferase; type 12 methyltransferase 5930332 8329168 Amir_4970 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003102642.1 5929742 R 446462 CDS YP_003102643.1 256378983 8329169 5930579..5931733 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: bur:Bcep18194_A4891 monooxygenase, FAD- binding; FAD-binding monooxygenase 5931733 8329169 Amir_4971 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003102643.1 5930579 D 446462 CDS YP_003102644.1 256378984 8329172 5933060..5934679 1 NC_013093.1 KEGG: MYH3; myosin, heavy chain 3, skeletal muscle, embryonic; K10352 myosin heavy chain; hypothetical protein 5934679 8329172 Amir_4974 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102644.1 5933060 D 446462 CDS YP_003102645.1 256378985 8329173 complement(5934962..5937010) 1 NC_013093.1 PFAM: MMPL domain protein; KEGG: bcz:BCZK2163 MmpL family integral membrane protein; MMPL domain-containing protein 5937010 8329173 Amir_4975 Actinosynnema mirum DSM 43827 MMPL domain-containing protein YP_003102645.1 5934962 R 446462 CDS YP_003102646.1 256378986 8329174 5937089..5937553 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: cak:Caul_0809 MarR family transcriptional regulator; MarR family transcriptional regulator 5937553 8329174 Amir_4976 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003102646.1 5937089 D 446462 CDS YP_003102647.1 256378987 8329175 5937606..5938742 1 NC_013093.1 TIGRFAM: glycosyltransferase, MGT family; PFAM: protein of unknown function DUF1205; KEGG: bsu:BSU12220 hypothetical protein; MGT family glycosyltransferase 5938742 8329175 Amir_4977 Actinosynnema mirum DSM 43827 MGT family glycosyltransferase YP_003102647.1 5937606 D 446462 CDS YP_003102648.1 256378988 8329176 5939063..5940232 1 NC_013093.1 TIGRFAM: glycosyltransferase, MGT family; PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; KEGG: ecf:ECH74115_1369 glycosyl transferase; MGT family glycosyltransferase 5940232 8329176 Amir_4978 Actinosynnema mirum DSM 43827 MGT family glycosyltransferase YP_003102648.1 5939063 D 446462 CDS YP_003102649.1 256378989 8329177 complement(5940308..5941630) 1 NC_013093.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: scl:sce2495 hemolysin; hypothetical protein 5941630 8329177 Amir_4979 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102649.1 5940308 R 446462 CDS YP_003102650.1 256378990 8329178 5941747..5942130 1 NC_013093.1 hypothetical protein 5942130 8329178 Amir_4980 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102650.1 5941747 D 446462 CDS YP_003102651.1 256378991 8329179 5942123..5942653 1 NC_013093.1 KEGG: GA24328 gene product from transcript GA24328- RA; hypothetical protein 5942653 8329179 Amir_4981 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102651.1 5942123 D 446462 CDS YP_003102652.1 256378992 8329180 5942646..5942987 1 NC_013093.1 KEGG: hne:HNE_2114 hypothetical protein; hypothetical protein 5942987 8329180 Amir_4982 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102652.1 5942646 D 446462 CDS YP_003102653.1 256378993 8329181 complement(5942988..5943158) 1 NC_013093.1 hypothetical protein 5943158 8329181 Amir_4983 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102653.1 5942988 R 446462 CDS YP_003102654.1 256378994 8329182 5943412..5945070 1 NC_013093.1 KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein 5945070 8329182 Amir_4984 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102654.1 5943412 D 446462 CDS YP_003102655.1 256378995 8329183 complement(5945067..5947130) 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; hypothetical protein 5947130 8329183 Amir_4985 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102655.1 5945067 R 446462 CDS YP_003102656.1 256378996 8329184 complement(5947208..5947435) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 5947435 8329184 Amir_4986 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102656.1 5947208 R 446462 CDS YP_003102657.1 256378997 8329185 complement(5947724..5948581) 1 NC_013093.1 SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 5948581 8329185 Amir_4987 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102657.1 5947724 R 446462 CDS YP_003102658.1 256378998 8329186 5949273..5949842 1 NC_013093.1 KEGG: bra:BRADO4970 hypothetical protein; hypothetical protein 5949842 8329186 Amir_4988 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102658.1 5949273 D 446462 CDS YP_003102659.1 256378999 8329187 complement(5949889..5950326) 1 NC_013093.1 hypothetical protein 5950326 8329187 Amir_4989 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102659.1 5949889 R 446462 CDS YP_003102660.1 256379000 8329188 5950479..5951099 1 NC_013093.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: nmc:NMC1726 hypothetical protein; Sua5/YciO/YrdC/YwlC family protein 5951099 8329188 Amir_4990 Actinosynnema mirum DSM 43827 Sua5/YciO/YrdC/YwlC family protein YP_003102660.1 5950479 D 446462 CDS YP_003102661.1 256379001 8329189 5951198..5951728 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 5951728 8329189 Amir_4991 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102661.1 5951198 D 446462 CDS YP_003102662.1 256379002 8329190 5951838..5952440 1 NC_013093.1 PFAM: hypothetical protein; KEGG: mch:Mchl_4966 hypothetical protein; hypothetical protein 5952440 8329190 Amir_4992 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102662.1 5951838 D 446462 CDS YP_003102663.1 256379003 8329191 5952533..5953585 1 NC_013093.1 hypothetical protein 5953585 8329191 Amir_4993 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102663.1 5952533 D 446462 CDS YP_003102664.1 256379004 8329192 complement(5953663..5954361) 1 NC_013093.1 KEGG: esa:ESA_01086 hypothetical protein; hypothetical protein 5954361 8329192 Amir_4994 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102664.1 5953663 R 446462 CDS YP_003102665.1 256379005 8329193 complement(5954405..5955061) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 5955061 8329193 Amir_4995 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102665.1 5954405 R 446462 CDS YP_003102666.1 256379006 8329194 complement(5955058..5956275) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: mch:Mchl_4713 histidine kinase; histidine kinase 5956275 8329194 Amir_4996 Actinosynnema mirum DSM 43827 histidine kinase YP_003102666.1 5955058 R 446462 CDS YP_003102667.1 256379007 8329195 5956415..5957347 1 NC_013093.1 KEGG: bte:BTH_II2362 esterase EstC; hypothetical protein 5957347 8329195 Amir_4997 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102667.1 5956415 D 446462 CDS YP_003102668.1 256379008 8329197 complement(5957860..5958462) 1 NC_013093.1 KEGG: HDA1511; class II RPD3 type histone deacetylase protein; K11407 histone deacetylase 6/10; histone deacetylase 5958462 8329197 Amir_4999 Actinosynnema mirum DSM 43827 histone deacetylase YP_003102668.1 5957860 R 446462 CDS YP_003102669.1 256379009 8329198 complement(5958438..5958995) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pla:Plav_1643 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 5958995 8329198 Amir_5000 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003102669.1 5958438 R 446462 CDS YP_003102670.1 256379010 8329199 complement(5959005..5960336) 1 NC_013093.1 PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bpt:Bpet3509 branched-chain alpha-keto acid dehydrogenase subunit E2; branched-chain alpha-keto acid dehydrogenase subunit E2 5960336 8329199 Amir_5001 Actinosynnema mirum DSM 43827 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_003102670.1 5959005 R 446462 CDS YP_003102671.1 256379011 8329200 complement(5960329..5961306) 1 NC_013093.1 PFAM: transketolase; transketolase; KEGG: nha:Nham_3108 transketolase, central region; transketolase 5961306 8329200 Amir_5002 Actinosynnema mirum DSM 43827 transketolase YP_003102671.1 5960329 R 446462 CDS YP_003102672.1 256379012 8329201 complement(5961381..5962493) 1 NC_013093.1 KEGG: ank:AnaeK_1422 pyruvate dehydrogenase (acetyl- transferring); TIGRFAM: pyruvate dehydrogenase (acetyl- transferring) E1 component, alpha subunit; PFAM: dehydrogenase E1 component; pyruvate dehydrogenase E1 component subunit alpha 5962493 8329201 Amir_5003 Actinosynnema mirum DSM 43827 pyruvate dehydrogenase E1 component subunit alpha YP_003102672.1 5961381 R 446462 CDS YP_003102673.1 256379013 8329202 5962605..5963093 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: har:HEAR0121 leucine-responsive regulatory protein; AsnC family transcriptional regulator 5963093 8329202 Amir_5004 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003102673.1 5962605 D 446462 CDS YP_003102674.1 256379014 8329203 complement(5963435..5964199) 1 NC_013093.1 PFAM: SCP-like extracellular; KEGG: SCP-like extracellular; SCP-like extracellular 5964199 8329203 Amir_5005 Actinosynnema mirum DSM 43827 SCP-like extracellular YP_003102674.1 5963435 R 446462 CDS YP_003102675.1 256379015 8329204 complement(5964442..5965722) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ent:Ent638_4061 two-component sensor protein; histidine kinase 5965722 8329204 Amir_5006 Actinosynnema mirum DSM 43827 histidine kinase YP_003102675.1 5964442 R 446462 CDS YP_003102676.1 256379016 8329205 complement(5965719..5966435) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pap:PSPA7_3717 KDP operon transcriptional regulatory protein KdpE; winged helix family two component transcriptional regulator 5966435 8329205 Amir_5007 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003102676.1 5965719 R 446462 CDS YP_003102677.1 256379017 8329206 5966846..5967412 1 NC_013093.1 KEGG: similar to Ras GTPase-activating protein- binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2); hypothetical protein 5967412 8329206 Amir_5008 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102677.1 5966846 D 446462 CDS YP_003102678.1 256379018 8329207 complement(5967691..5968167) 1 NC_013093.1 KEGG: cti:RALTA_A3069 membrane bound protein, weak cytochrome C domains; hypothetical protein 5968167 8329207 Amir_5009 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102678.1 5967691 R 446462 CDS YP_003102679.1 256379019 8329208 complement(5968155..5970035) 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: bxe:Bxe_A3516 transposase; aminoglycoside phosphotransferase 5970035 8329208 Amir_5010 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003102679.1 5968155 R 446462 CDS YP_003102680.1 256379020 8329209 5970190..5970402 1 NC_013093.1 hypothetical protein 5970402 8329209 Amir_5011 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102680.1 5970190 D 446462 CDS YP_003102681.1 256379021 8329210 5970511..5971992 1 NC_013093.1 KEGG: mrd:Mrad2831_4352 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 5971992 8329210 Amir_5012 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003102681.1 5970511 D 446462 CDS YP_003102682.1 256379022 8329211 complement(5971989..5972759) 1 NC_013093.1 PFAM: cyclase family protein; KEGG: hch:HCH_01555 metal-dependent hydrolase; cyclase family protein 5972759 8329211 Amir_5013 Actinosynnema mirum DSM 43827 cyclase family protein YP_003102682.1 5971989 R 446462 CDS YP_003102683.1 256379023 8329212 complement(5973146..5974246) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: smd:Smed_2747 alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain-containing protein 5974246 8329212 Amir_5014 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003102683.1 5973146 R 446462 CDS YP_003102684.1 256379024 8329213 complement(5974243..5974656) 1 NC_013093.1 PFAM: thioesterase superfamily protein; KEGG: bmj:BMULJ_01339 thioesterase; thioesterase superfamily protein 5974656 8329213 Amir_5015 Actinosynnema mirum DSM 43827 thioesterase superfamily protein YP_003102684.1 5974243 R 446462 CDS YP_003102685.1 256379025 8329214 5975219..5976625 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: mxa:MXAN_6248 cyclic nucleotide-binding domain protein; Crp/Fnr family transcriptional regulator 5976625 8329214 Amir_5016 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003102685.1 5975219 D 446462 CDS YP_003102686.1 256379026 8329215 5976672..5978081 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: scl:sce1442 nucleotide-binding protein; Crp/Fnr family transcriptional regulator 5978081 8329215 Amir_5017 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003102686.1 5976672 D 446462 CDS YP_003102687.1 256379027 8329216 5978465..5979505 1 NC_013093.1 PFAM: polyprenyl synthetase; KEGG: sfu:Sfum_1417 polyprenyl synthetase; polyprenyl synthetase 5979505 8329216 Amir_5018 Actinosynnema mirum DSM 43827 polyprenyl synthetase YP_003102687.1 5978465 D 446462 CDS YP_003102688.1 256379028 8329217 5979577..5980500 1 NC_013093.1 KEGG: acr:Acry_1832 hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; hydroxymethylbutenyl pyrophosphate reductase 5980500 8329217 Amir_5019 Actinosynnema mirum DSM 43827 hydroxymethylbutenyl pyrophosphate reductase YP_003102688.1 5979577 D 446462 CDS YP_003102689.1 256379029 8329218 5980497..5982353 1 NC_013093.1 PFAM: transketolase; transketolase; KEGG: mgm:Mmc1_1048 1-deoxy-D-xylulose-5-phosphate synthase; transketolase 5982353 8329218 Amir_5020 Actinosynnema mirum DSM 43827 transketolase YP_003102689.1 5980497 D 446462 CDS YP_003102690.1 256379030 8329219 5982456..5983265 1 NC_013093.1 KEGG: rsr-1; SR protein related; hypothetical protein 5983265 8329219 Amir_5021 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102690.1 5982456 D 446462 CDS YP_003102691.1 256379031 8329220 5983470..5983808 1 NC_013093.1 PFAM: protein of unknown function DUF742; hypothetical protein 5983808 8329220 Amir_5022 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102691.1 5983470 D 446462 CDS YP_003102692.1 256379032 8329221 complement(5983891..5984628) 1 NC_013093.1 transmembrane anti-sigma factor 5984628 8329221 Amir_5023 Actinosynnema mirum DSM 43827 transmembrane anti-sigma factor YP_003102692.1 5983891 R 446462 CDS YP_003102693.1 256379033 8329222 complement(5984634..5985200) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpe:RPE_0795 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit 5985200 8329222 Amir_5024 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102693.1 5984634 R 446462 CDS YP_003102694.1 256379034 8329223 5985832..5987058 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: sfu:Sfum_0186 glycosyl transferase, family 2; family 2 glycosyl transferase 5987058 8329223 Amir_5025 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003102694.1 5985832 D 446462 CDS YP_003102695.1 256379035 8329225 complement(5987425..5988459) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: rso:RSc0632 NADP-dependent alcohol dehydrogenase oxidoreductase protein; alcohol dehydrogenase GroES domain-containing protein 5988459 8329225 Amir_5027 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003102695.1 5987425 R 446462 CDS YP_003102696.1 256379036 8329226 5988557..5989141 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 5989141 8329226 Amir_5028 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102696.1 5988557 D 446462 CDS YP_003102697.1 256379037 8329227 5989207..5989683 1 NC_013093.1 PFAM: protein of unknown function DUF1232; KEGG: mca:MCA0116 hypothetical protein; hypothetical protein 5989683 8329227 Amir_5029 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102697.1 5989207 D 446462 CDS YP_003102698.1 256379038 8329228 complement(5989648..5990823) 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: afw:Anae109_3197 hypothetical protein; hypothetical protein 5990823 8329228 Amir_5030 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102698.1 5989648 R 446462 CDS YP_003102699.1 256379039 8329229 complement(5990820..5990927) 1 NC_013093.1 hypothetical protein 5990927 8329229 Amir_5031 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102699.1 5990820 R 446462 CDS YP_003102700.1 256379040 8329230 complement(5991068..5991850) 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: dar:Daro_0405 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 5991850 8329230 Amir_5032 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003102700.1 5991068 R 446462 CDS YP_003102701.1 256379041 8329231 5991988..5993157 1 NC_013093.1 PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver; KEGG: mag:amb3537 serine phosphatase RsbU, regulator of sigma subunit; response regulator receiver modulated serine phosphatase 5993157 8329231 Amir_5033 Actinosynnema mirum DSM 43827 response regulator receiver modulated serine phosphatase YP_003102701.1 5991988 D 446462 CDS YP_003102702.1 256379042 8329232 5993160..5994656 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dal:Dalk_3400 histidine kinase; histidine kinase 5994656 8329232 Amir_5034 Actinosynnema mirum DSM 43827 histidine kinase YP_003102702.1 5993160 D 446462 CDS YP_003102703.1 256379043 8329233 5994653..5995090 1 NC_013093.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mag:amb2979 FOG: CheY-like receiver; response regulator receiver protein 5995090 8329233 Amir_5035 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003102703.1 5994653 D 446462 CDS YP_003102704.1 256379044 8329234 5995182..5995937 1 NC_013093.1 KEGG: ade:Adeh_3125 alpha/beta hydrolase fold-1; alpha/beta hydrolase fold-1 5995937 8329234 Amir_5036 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold-1 YP_003102704.1 5995182 D 446462 CDS YP_003102705.1 256379045 8329235 complement(5996029..5996250) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 5996250 8329235 Amir_5037 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102705.1 5996029 R 446462 CDS YP_003102706.1 256379046 8329236 complement(5996247..5997110) 1 NC_013093.1 SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 5997110 8329236 Amir_5038 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003102706.1 5996247 R 446462 CDS YP_003102707.1 256379047 8329237 5997300..5997644 1 NC_013093.1 hypothetical protein 5997644 8329237 Amir_5039 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102707.1 5997300 D 446462 CDS YP_003102708.1 256379048 8329238 complement(5997598..5997861) 1 NC_013093.1 hypothetical protein 5997861 8329238 Amir_5040 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102708.1 5997598 R 446462 CDS YP_003102709.1 256379049 8329239 complement(5998125..5998613) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 5998613 8329239 Amir_5041 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102709.1 5998125 R 446462 CDS YP_003102710.1 256379050 8329240 complement(5998912..5999094) 1 NC_013093.1 hypothetical protein 5999094 8329240 Amir_5042 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102710.1 5998912 R 446462 CDS YP_003102711.1 256379051 8329241 complement(5999351..6001408) 1 NC_013093.1 KEGG: aeh:Mlg_1110 hypothetical protein; superfamily I DNA and RNA helicase-like protein 6001408 8329241 Amir_5043 Actinosynnema mirum DSM 43827 superfamily I DNA and RNA helicase-like protein YP_003102711.1 5999351 R 446462 CDS YP_003102712.1 256379052 8329242 6001996..6003132 1 NC_013093.1 KEGG: afw:Anae109_1986 extracellular HAF; hypothetical protein 6003132 8329242 Amir_5044 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102712.1 6001996 D 446462 CDS YP_003102713.1 256379053 8329243 complement(6003391..6003750) 1 NC_013093.1 hypothetical protein 6003750 8329243 Amir_5045 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102713.1 6003391 R 446462 CDS YP_003102714.1 256379054 8329244 complement(6003870..6004451) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 6004451 8329244 Amir_5046 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102714.1 6003870 R 446462 CDS YP_003102715.1 256379055 8329245 6004530..6005375 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bid:Bind_1825 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6005375 8329245 Amir_5047 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102715.1 6004530 D 446462 CDS YP_003102716.1 256379056 8329246 6005410..6006147 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bur:Bcep18194_B1012 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6006147 8329246 Amir_5048 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102716.1 6005410 D 446462 CDS YP_003102717.1 256379057 8329247 complement(6006185..6009280) 1 NC_013093.1 PFAM: amidohydrolase; hypothetical protein; KEGG: ade:Adeh_2230 hypothetical protein; amidohydrolase 6009280 8329247 Amir_5049 Actinosynnema mirum DSM 43827 amidohydrolase YP_003102717.1 6006185 R 446462 CDS YP_003102718.1 256379058 8329248 complement(6009463..6010116) 1 NC_013093.1 hypothetical protein 6010116 8329248 Amir_5050 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102718.1 6009463 R 446462 CDS YP_003102719.1 256379059 8329249 6010206..6011885 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: mno:Mnod_8094 transposase IS4 family protein; transposase IS4 family protein 6011885 8329249 Amir_5051 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003102719.1 6010206 D 446462 CDS YP_003102720.1 256379060 8329250 complement(6011951..6014152) 1 NC_013093.1 KEGG: bcz:BCZK2539 UvrD/Rep helicase family protein; superfamily I DNA and RNA helicase-like protein 6014152 8329250 Amir_5052 Actinosynnema mirum DSM 43827 superfamily I DNA and RNA helicase-like protein YP_003102720.1 6011951 R 446462 CDS YP_003102721.1 256379061 8329251 complement(6014361..6015176) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: spe:Spro_3426 ABC transporter-related protein; ABC transporter 6015176 8329251 Amir_5053 Actinosynnema mirum DSM 43827 ABC transporter YP_003102721.1 6014361 R 446462 CDS YP_003102722.1 256379062 8329252 complement(6015173..6016204) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: ppg:PputGB1_1806 transport system permease protein; transport system permease 6016204 8329252 Amir_5054 Actinosynnema mirum DSM 43827 transport system permease YP_003102722.1 6015173 R 446462 CDS YP_003102723.1 256379063 8329253 complement(6016201..6017202) 1 NC_013093.1 PFAM: transport system permease protein; KEGG: atc:AGR_pAT_449 ferric enterobactin transport protein FepD; transport system permease 6017202 8329253 Amir_5055 Actinosynnema mirum DSM 43827 transport system permease YP_003102723.1 6016201 R 446462 CDS YP_003102724.1 256379064 8329254 complement(6017298..6018260) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: bha:BH3724 2-keto-3-deoxygluconate kinase; PfkB domain-containing protein 6018260 8329254 Amir_5056 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003102724.1 6017298 R 446462 CDS YP_003102725.1 256379065 8329255 complement(6018257..6019279) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: gdi:GDI1202 L-idonate 5-dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 6019279 8329255 Amir_5057 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003102725.1 6018257 R 446462 CDS YP_003102726.1 256379066 8329256 complement(6019276..6020682) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: eca:ECA0919 transport protein; major facilitator superfamily protein 6020682 8329256 Amir_5058 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003102726.1 6019276 R 446462 CDS YP_003102727.1 256379067 8329257 complement(6020808..6022235) 1 NC_013093.1 PFAM: mannitol dehydrogenase domain; mannitol dehydrogenase rossman domain; KEGG: mmr:Mmar10_0223 mannitol dehydrogenase; mannitol dehydrogenase domain-containing protein 6022235 8329257 Amir_5059 Actinosynnema mirum DSM 43827 mannitol dehydrogenase domain-containing protein YP_003102727.1 6020808 R 446462 CDS YP_003102728.1 256379068 8329258 complement(6022232..6023440) 1 NC_013093.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0917 starvation sensing mandelate racemase / muconate lactonizing enzyme; mandelate racemase/muconate lactonizing protein 6023440 8329258 Amir_5060 Actinosynnema mirum DSM 43827 mandelate racemase/muconate lactonizing protein YP_003102728.1 6022232 R 446462 CDS YP_003102729.1 256379069 8329259 6024619..6025329 1 NC_013093.1 PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; KEGG: sme:SMa0065 GntR family transcriptional regulator; GntR family transcriptional regulator 6025329 8329259 Amir_5061 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003102729.1 6024619 D 446462 CDS YP_003102730.1 256379070 8329260 6025326..6025625 1 NC_013093.1 hypothetical protein 6025625 8329260 Amir_5062 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102730.1 6025326 D 446462 CDS YP_003102731.1 256379071 8329261 complement(6025703..6025897) 1 NC_013093.1 PFAM: MbtH domain protein; KEGG: bbt:BBta_4111 hypothetical protein; MbtH domain-containing protein 6025897 8329261 Amir_5063 Actinosynnema mirum DSM 43827 MbtH domain-containing protein YP_003102731.1 6025703 R 446462 CDS YP_003102732.1 256379072 8329262 complement(6025894..6039243) 1 NC_013093.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3636 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 6039243 8329262 Amir_5064 Actinosynnema mirum DSM 43827 amino acid adenylation domain-containing protein YP_003102732.1 6025894 R 446462 CDS YP_003102733.1 256379073 8329263 complement(6039351..6040361) 1 NC_013093.1 PFAM: periplasmic binding protein; KEGG: atc:AGR_pAT_447 DtxR/iron regulated lipoprotein precursor; periplasmic binding protein 6040361 8329263 Amir_5065 Actinosynnema mirum DSM 43827 periplasmic binding protein YP_003102733.1 6039351 R 446462 CDS YP_003102734.1 256379074 8329264 complement(6040429..6041757) 1 NC_013093.1 KEGG: dac:Daci_4749 L-lysine 6-monooxygenase (NADPH); L-lysine 6-monooxygenase (NADPH) 6041757 8329264 Amir_5066 Actinosynnema mirum DSM 43827 L-lysine 6-monooxygenase (NADPH) YP_003102734.1 6040429 R 446462 CDS YP_003102735.1 256379075 8329265 6041895..6043544 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; KEGG: met:M446_4330 lipid ABC transporter ATPase/inner membrane protein; ABC transporter 6043544 8329265 Amir_5067 Actinosynnema mirum DSM 43827 ABC transporter YP_003102735.1 6041895 D 446462 CDS YP_003102736.1 256379076 8329266 6043618..6045618 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: afw:Anae109_3226 ABC transporter; ABC transporter 6045618 8329266 Amir_5068 Actinosynnema mirum DSM 43827 ABC transporter YP_003102736.1 6043618 D 446462 CDS YP_003102737.1 256379077 8329267 6045677..6046321 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: beta-lactamase domain protein; beta-lactamase domain-containing protein 6046321 8329267 Amir_5069 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003102737.1 6045677 D 446462 CDS YP_003102738.1 256379078 8329268 complement(6046382..6047443) 1 NC_013093.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: Animal peptidoglycan recognition protein PGRP; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: similar to PGRP-SC1a protein; N-acetylmuramoyl-L-alanine amidase family 2 6047443 8329268 Amir_5070 Actinosynnema mirum DSM 43827 N-acetylmuramoyl-L-alanine amidase family 2 YP_003102738.1 6046382 R 446462 CDS YP_003102739.1 256379079 8329269 complement(6047597..6048781) 1 NC_013093.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_6060 amine oxidase, flavin- containing; amine oxidase 6048781 8329269 Amir_5071 Actinosynnema mirum DSM 43827 amine oxidase YP_003102739.1 6047597 R 446462 CDS YP_003102740.1 256379080 8329270 6048948..6050303 1 NC_013093.1 KEGG: endo-1,4-beta-xylanase; K01181 endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase 6050303 8329270 Amir_5072 Actinosynnema mirum DSM 43827 endo-1,4-beta-xylanase YP_003102740.1 6048948 D 446462 CDS YP_003102741.1 256379081 8329271 complement(6050307..6050840) 1 NC_013093.1 hypothetical protein 6050840 8329271 Amir_5073 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102741.1 6050307 R 446462 CDS YP_003102742.1 256379082 8329272 complement(6050919..6051722) 1 NC_013093.1 PFAM: glycoside hydrolase family 16; KEGG: glycoside hydrolase; glycoside hydrolase family protein 6051722 8329272 Amir_5074 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003102742.1 6050919 R 446462 CDS YP_003102743.1 256379083 8329273 complement(6051936..6052802) 1 NC_013093.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 6052802 8329273 Amir_5075 Actinosynnema mirum DSM 43827 chromosome replication initiation inhibitor protein YP_003102743.1 6051936 R 446462 CDS YP_003102744.1 256379084 8329274 6053389..6053505 1 NC_013093.1 hypothetical protein 6053505 8329274 Amir_5076 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102744.1 6053389 D 446462 CDS YP_003102745.1 256379085 8329275 6053634..6054221 1 NC_013093.1 PFAM: lysine exporter protein (LYSE/YGGA); KEGG: smt:Smal_1176 lysine exporter protein (LysE/YggA); lysine exporter protein LysE/YggA 6054221 8329275 Amir_5077 Actinosynnema mirum DSM 43827 lysine exporter protein LysE/YggA YP_003102745.1 6053634 D 446462 CDS YP_003102746.1 256379086 8329276 6054346..6054978 1 NC_013093.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_1010 bifunctional deaminase- reductase-like; bifunctional deaminase-reductase domain-containing protein 6054978 8329276 Amir_5078 Actinosynnema mirum DSM 43827 bifunctional deaminase-reductase domain-containing protein YP_003102746.1 6054346 D 446462 CDS YP_003102747.1 256379087 8329277 6055514..6056065 1 NC_013093.1 KEGG: bcm:Bcenmc03_6355 outer membrane autotransporter; hypothetical protein 6056065 8329277 Amir_5079 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102747.1 6055514 D 446462 CDS YP_003102748.1 256379088 8329278 complement(6056116..6056865) 1 NC_013093.1 KEGG: bac:BamMC406_5247 IclR family transcriptional regulator; TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; IclR family transcriptional regulator 6056865 8329278 Amir_5080 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003102748.1 6056116 R 446462 CDS YP_003102749.1 256379089 8329279 complement(6056858..6057226) 1 NC_013093.1 PFAM: carboxymuconolactone decarboxylase; KEGG: mlo:mlr7207 gamma carboxymuconolactone decarboxylase; carboxymuconolactone decarboxylase 6057226 8329279 Amir_5081 Actinosynnema mirum DSM 43827 carboxymuconolactone decarboxylase YP_003102749.1 6056858 R 446462 CDS YP_003102750.1 256379090 8329280 complement(6057223..6057333) 1 NC_013093.1 hypothetical protein 6057333 8329280 Amir_5082 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102750.1 6057223 R 446462 CDS YP_003102751.1 256379091 8329281 complement(6057442..6058224) 1 NC_013093.1 TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; KEGG: swi:Swit_0978 3-oxoadipate enol-lactonase; 3-oxoadipate enol-lactonase 6058224 8329281 Amir_5083 Actinosynnema mirum DSM 43827 3-oxoadipate enol-lactonase YP_003102751.1 6057442 R 446462 CDS YP_003102752.1 256379092 8329282 complement(6058199..6058765) 1 NC_013093.1 KEGG: reh:H16_B2290 protocatechuate 3,4-dioxygenase alpha chain; TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase; protocatechuate 3,4-dioxygenase subunit alpha 6058765 8329282 Amir_5084 Actinosynnema mirum DSM 43827 protocatechuate 3,4-dioxygenase subunit alpha YP_003102752.1 6058199 R 446462 CDS YP_003102753.1 256379093 8329283 complement(6058758..6059474) 1 NC_013093.1 KEGG: pfo:Pfl01_1270 protocatechuate 3,4- dioxygenase, beta subunit; TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; protocatechuate 3,4-dioxygenase subunit beta 6059474 8329283 Amir_5085 Actinosynnema mirum DSM 43827 protocatechuate 3,4-dioxygenase subunit beta YP_003102753.1 6058758 R 446462 CDS YP_003102754.1 256379094 8329284 complement(6059528..6060283) 1 NC_013093.1 PFAM: coenzyme A transferase; KEGG: xcv:XCV0379 glutaconate CoA transferase subunit B; glutaconate CoA-transferase 6060283 8329284 Amir_5086 Actinosynnema mirum DSM 43827 glutaconate CoA-transferase YP_003102754.1 6059528 R 446462 CDS YP_003102755.1 256379095 8329285 complement(6060280..6061077) 1 NC_013093.1 PFAM: coenzyme A transferase; KEGG: pag:PLES_02231 CoA transferase, subunit A; coenzyme A transferase 6061077 8329285 Amir_5087 Actinosynnema mirum DSM 43827 coenzyme A transferase YP_003102755.1 6060280 R 446462 CDS YP_003102756.1 256379096 8329286 6061235..6061837 1 NC_013093.1 KEGG: noc:Noc_2708 hypothetical protein; hypothetical protein 6061837 8329286 Amir_5088 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102756.1 6061235 D 446462 CDS YP_003102757.1 256379097 8329287 6061834..6065136 1 NC_013093.1 SMART: ATPase AAA; KEGG: met:M446_5114 ATPase AAA; ATPase AAA 6065136 8329287 Amir_5089 Actinosynnema mirum DSM 43827 ATPase AAA YP_003102757.1 6061834 D 446462 CDS YP_003102758.1 256379098 8329288 complement(6065558..6067021) 1 NC_013093.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: gsu:GSU0700 sensory box/response regulator; protein serine/threonine phosphatase 6067021 8329288 Amir_5090 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003102758.1 6065558 R 446462 CDS YP_003102759.1 256379099 8329289 6067224..6071663 1 NC_013093.1 KEGG: ank:AnaeK_4253 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; GAF sensor hybrid histidine kinase 6071663 8329289 Amir_5091 Actinosynnema mirum DSM 43827 GAF sensor hybrid histidine kinase YP_003102759.1 6067224 D 446462 CDS YP_003102760.1 256379100 8329290 complement(6071713..6072039) 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; anti-sigma-factor antagonist 6072039 8329290 Amir_5092 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003102760.1 6071713 R 446462 CDS YP_003102761.1 256379101 8329291 6072173..6072571 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: met:M446_2753 signal transduction histidine kinase; anti-sigma regulatory factor, serine/threonine protein kinase 6072571 8329291 Amir_5093 Actinosynnema mirum DSM 43827 anti-sigma regulatory factor, serine/threonine protein kinase YP_003102761.1 6072173 D 446462 CDS YP_003102762.1 256379102 8329292 6073230..6074144 1 NC_013093.1 PFAM: Ppx/GppA phosphatase; KEGG: acp:A2cp1_0693 Ppx/GppA phosphatase; Ppx/GppA phosphatase 6074144 8329292 Amir_5094 Actinosynnema mirum DSM 43827 Ppx/GppA phosphatase YP_003102762.1 6073230 D 446462 CDS YP_003102763.1 256379103 8329293 6074158..6074544 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sus:Acid_2843 anti-sigma-factor antagonist; anti-sigma-factor antagonist 6074544 8329293 Amir_5095 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003102763.1 6074158 D 446462 CDS YP_003102764.1 256379104 8329294 6074578..6074958 1 NC_013093.1 hypothetical protein 6074958 8329294 Amir_5096 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102764.1 6074578 D 446462 CDS YP_003102765.1 256379105 8329295 6074970..6075452 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pzu:PHZ_c2921 acetyltransferase, GNAT family; GCN5-like N-acetyltransferase 6075452 8329295 Amir_5097 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003102765.1 6074970 D 446462 CDS YP_003102766.1 256379106 8329296 6075665..6076804 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: mpo:Mpop_1275 dehydrogenase protein; luciferase-like monooxygenase 6076804 8329296 Amir_5098 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003102766.1 6075665 D 446462 CDS YP_003102767.1 256379107 8329297 6076852..6077040 1 NC_013093.1 hypothetical protein 6077040 8329297 Amir_5099 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102767.1 6076852 D 446462 CDS YP_003102768.1 256379108 8329298 complement(6077133..6077522) 1 NC_013093.1 KEGG: TIMP2; TIMP metallopeptidase inhibitor 2; TIMP2; TIMP metallopeptidase inhibitor 2 6077522 8329298 Amir_5100 Actinosynnema mirum DSM 43827 TIMP2; TIMP metallopeptidase inhibitor 2 YP_003102768.1 6077133 R 446462 CDS YP_003102769.1 256379109 8329299 6077591..6077713 1 NC_013093.1 hypothetical protein 6077713 8329299 Amir_5101 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102769.1 6077591 D 446462 CDS YP_003102770.1 256379110 8329300 6077809..6078789 1 NC_013093.1 KEGG: vei:Veis_1391 periplasmic binding protein/LacI transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 6078789 8329300 Amir_5102 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003102770.1 6077809 D 446462 CDS YP_003102771.1 256379111 8329301 6078905..6079810 1 NC_013093.1 PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: peptidase U61, LD-carboxypeptidase A; peptidase U61 LD-carboxypeptidase A 6079810 8329301 Amir_5103 Actinosynnema mirum DSM 43827 peptidase U61 LD-carboxypeptidase A YP_003102771.1 6078905 D 446462 CDS YP_003102772.1 256379112 8329302 complement(6080073..6080927) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: pag:PLES_17341 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 6080927 8329302 Amir_5104 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102772.1 6080073 R 446462 CDS YP_003102773.1 256379113 8329303 6080997..6081590 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: met:M446_2111 TetR family transcriptional regulator; TetR family transcriptional regulator 6081590 8329303 Amir_5105 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102773.1 6080997 D 446462 CDS YP_003102774.1 256379114 8329304 complement(6081622..6082356) 1 NC_013093.1 hypothetical protein 6082356 8329304 Amir_5106 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102774.1 6081622 R 446462 CDS YP_003102775.1 256379115 8329305 6082824..6083339 1 NC_013093.1 PFAM: chitin-binding domain 3 protein; KEGG: hch:HCH_03973 N-acetylglucosamine-binding protein A; chitin-binding domain 3 protein 6083339 8329305 Amir_5107 Actinosynnema mirum DSM 43827 chitin-binding domain 3 protein YP_003102775.1 6082824 D 446462 CDS YP_003102776.1 256379116 8329306 6083782..6083946 1 NC_013093.1 hypothetical protein 6083946 8329306 Amir_5108 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102776.1 6083782 D 446462 CDS YP_003102777.1 256379117 8329307 6083946..6085697 1 NC_013093.1 KEGG: GK22681 gene product from transcript GK22681- RA; hypothetical protein 6085697 8329307 Amir_5109 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102777.1 6083946 D 446462 CDS YP_003102778.1 256379118 8329308 complement(6086748..6086921) 1 NC_013093.1 PFAM: CsbD family protein; KEGG: pen:PSEEN4005 hypothetical protein; CsbD family protein 6086921 8329308 Amir_5110 Actinosynnema mirum DSM 43827 CsbD family protein YP_003102778.1 6086748 R 446462 CDS YP_003102779.1 256379119 8329309 6087207..6087698 1 NC_013093.1 PFAM: ANTAR domain protein; ANTAR domain-containing protein with unknown sensor 6087698 8329309 Amir_5111 Actinosynnema mirum DSM 43827 ANTAR domain-containing protein with unknown sensor YP_003102779.1 6087207 D 446462 CDS YP_003102780.1 256379120 8329310 complement(6087647..6089539) 1 NC_013093.1 KEGG: gsu:GSU2358 isoamylase family protein; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; malto-oligosyltrehalose trehalohydrolase 6089539 8329310 Amir_5112 Actinosynnema mirum DSM 43827 malto-oligosyltrehalose trehalohydrolase YP_003102780.1 6087647 R 446462 CDS YP_003102781.1 256379121 8329311 complement(6089536..6091785) 1 NC_013093.1 KEGG: reu:Reut_B4234 alpha amylase domain- containing protein; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; malto-oligosyltrehalose synthase 6091785 8329311 Amir_5113 Actinosynnema mirum DSM 43827 malto-oligosyltrehalose synthase YP_003102781.1 6089536 R 446462 CDS YP_003102782.1 256379122 8329312 complement(6091782..6093908) 1 NC_013093.1 KEGG: nmu:Nmul_A1401 glycogen debranching protein GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; glycogen debranching protein GlgX 6093908 8329312 Amir_5114 Actinosynnema mirum DSM 43827 glycogen debranching protein GlgX YP_003102782.1 6091782 R 446462 CDS YP_003102783.1 256379123 8329313 complement(6094069..6094407) 1 NC_013093.1 hypothetical protein 6094407 8329313 Amir_5115 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102783.1 6094069 R 446462 CDS YP_003102784.1 256379124 8329314 complement(6094512..6096590) 1 NC_013093.1 KEGG: bpt:Bpet2366 hypothetical protein; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; 4-alpha-glucanotransferase 6096590 8329314 Amir_5116 Actinosynnema mirum DSM 43827 4-alpha-glucanotransferase YP_003102784.1 6094512 R 446462 CDS YP_003102785.1 256379125 8329315 complement(6096709..6097671) 1 NC_013093.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SM_b20014 transcriptional regulator protein; LacI family transcriptional regulator 6097671 8329315 Amir_5117 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003102785.1 6096709 R 446462 CDS YP_003102786.1 256379126 8329316 6097783..6098235 1 NC_013093.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: afw:Anae109_2778 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 6098235 8329316 Amir_5118 Actinosynnema mirum DSM 43827 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_003102786.1 6097783 D 446462 CDS YP_003102787.1 256379127 8329317 complement(6098239..6099222) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: pzu:PHZ_c2545 5,10- methylenetetrahydromethanopterin reductase; luciferase-like monooxygenase 6099222 8329317 Amir_5119 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003102787.1 6098239 R 446462 CDS YP_003102788.1 256379128 8329318 complement(6099506..6100372) 1 NC_013093.1 PFAM: peptidase M23; KEGG: pde:Pden_4473 peptidase M23B; peptidase M23 6100372 8329318 Amir_5120 Actinosynnema mirum DSM 43827 peptidase M23 YP_003102788.1 6099506 R 446462 CDS YP_003102789.1 256379129 8329319 complement(6100961..6103042) 1 NC_013093.1 PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: rce:RC1_2700 penicillin-binding protein, 1A family; glycosyl transferase family protein 6103042 8329319 Amir_5121 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003102789.1 6100961 R 446462 CDS YP_003102790.1 256379130 8329320 complement(6103337..6104380) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: sme:SM_b21462 sugar kinase protein; PfkB domain-containing protein 6104380 8329320 Amir_5122 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003102790.1 6103337 R 446462 CDS YP_003102791.1 256379131 8329321 complement(6104393..6105124) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: pla:Plav_0951 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 6105124 8329321 Amir_5123 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102791.1 6104393 R 446462 CDS YP_003102792.1 256379132 8329322 6105572..6106390 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: mrd:Mrad2831_0619 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 6106390 8329322 Amir_5124 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003102792.1 6105572 D 446462 CDS YP_003102793.1 256379133 8329324 6106632..6107186 1 NC_013093.1 KEGG: pap:PSPA7_5262 hypothetical protein; hypothetical protein 6107186 8329324 Amir_5126 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102793.1 6106632 D 446462 CDS YP_003102794.1 256379134 8329325 complement(6107179..6108075) 1 NC_013093.1 PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; LysR family transcriptional regulator 6108075 8329325 Amir_5127 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003102794.1 6107179 R 446462 CDS YP_003102795.1 256379135 8329326 6108096..6108908 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mll2997 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 6108908 8329326 Amir_5128 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102795.1 6108096 D 446462 CDS YP_003102796.1 256379136 8329327 complement(6108954..6109718) 1 NC_013093.1 PFAM: regulatory protein DeoR; regulatory protein GntR HTH; SMART: regulatory protein DeoR; KEGG: aba:Acid345_0659 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 6109718 8329327 Amir_5129 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003102796.1 6108954 R 446462 CDS YP_003102797.1 256379137 8329328 6109816..6110553 1 NC_013093.1 KEGG: bha:BH0227 hypothetical protein; hypothetical protein 6110553 8329328 Amir_5130 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102797.1 6109816 D 446462 CDS YP_003102798.1 256379138 8329329 complement(6111091..6113037) 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: sat:SYN_01564 phospholipid-lipopolysaccharide ABC transporter; ABC transporter 6113037 8329329 Amir_5131 Actinosynnema mirum DSM 43827 ABC transporter YP_003102798.1 6111091 R 446462 CDS YP_003102799.1 256379139 8329330 complement(6113533..6114342) 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: dal:Dalk_3354 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 6114342 8329330 Amir_5132 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003102799.1 6113533 R 446462 CDS YP_003102800.1 256379140 8329331 complement(6114412..6114621) 1 NC_013093.1 transcriptional regulator 6114621 8329331 Amir_5133 Actinosynnema mirum DSM 43827 transcriptional regulator YP_003102800.1 6114412 R 446462 CDS YP_003102801.1 256379141 8329332 complement(6114785..6116413) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6041 ABC transporter, ATP-binding protein; ABC transporter 6116413 8329332 Amir_5134 Actinosynnema mirum DSM 43827 ABC transporter YP_003102801.1 6114785 R 446462 CDS YP_003102802.1 256379142 8329333 6116622..6117377 1 NC_013093.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 6117377 fabG 8329333 fabG Actinosynnema mirum DSM 43827 3-ketoacyl-(acyl-carrier-protein) reductase YP_003102802.1 6116622 D 446462 CDS YP_003102803.1 256379143 8329334 complement(6117418..6117855) 1 NC_013093.1 KEGG: scl:sce9133 secreted protein; hypothetical protein 6117855 8329334 Amir_5136 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102803.1 6117418 R 446462 CDS YP_003102804.1 256379144 8329335 complement(6117848..6118363) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: xau:Xaut_1595 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 6118363 8329335 Amir_5137 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102804.1 6117848 R 446462 CDS YP_003102805.1 256379145 8329336 complement(6118368..6118742) 1 NC_013093.1 KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein 6118742 8329336 Amir_5138 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102805.1 6118368 R 446462 CDS YP_003102806.1 256379146 8329337 complement(6118859..6119437) 1 NC_013093.1 KEGG: bur:Bcep18194_A4859 hypothetical protein; hypothetical protein 6119437 8329337 Amir_5139 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102806.1 6118859 R 446462 CDS YP_003102807.1 256379147 8329338 6119672..6120649 1 NC_013093.1 hypothetical protein 6120649 8329338 Amir_5140 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102807.1 6119672 D 446462 CDS YP_003102808.1 256379148 8329339 complement(6120837..6123653) 1 NC_013093.1 PFAM: proprotein convertase P; KEGG: aba:Acid345_4222 hypothetical protein; proprotein convertase P 6123653 8329339 Amir_5141 Actinosynnema mirum DSM 43827 proprotein convertase P YP_003102808.1 6120837 R 446462 CDS YP_003102809.1 256379149 8329340 complement(6123800..6125368) 1 NC_013093.1 KEGG: aba:Acid345_0225 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; deoxyguanosinetriphosphate triphosphohydrolase 6125368 8329340 Amir_5142 Actinosynnema mirum DSM 43827 deoxyguanosinetriphosphate triphosphohydrolase YP_003102809.1 6123800 R 446462 CDS YP_003102810.1 256379150 8329345 6131515..6132954 1 NC_013093.1 PFAM: MASE1 domain protein; KEGG: sse:Ssed_3344 signal transduction protein; integral membrane sensor protein 6132954 8329345 Amir_5143 Actinosynnema mirum DSM 43827 integral membrane sensor protein YP_003102810.1 6131515 D 446462 CDS YP_003102811.1 256379151 8329346 6132958..6134037 1 NC_013093.1 TIGRFAM: lycopene cyclase family protein; PFAM: Lycopene beta and epsilon cyclase; KEGG: hypothetical protein; K06443 lycopene beta cyclase; lycopene cyclase family protein 6134037 8329346 Amir_5144 Actinosynnema mirum DSM 43827 lycopene cyclase family protein YP_003102811.1 6132958 D 446462 CDS YP_003102812.1 256379152 8329347 6134080..6135777 1 NC_013093.1 KEGG: cti:RALTA_B1157 diguanylate cyclase (GGDEF domain) and C-di-GMP phosphodiesterase (EAL domain)); TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; diguanylate cyclase/phosphodiesterase 6135777 8329347 Amir_5145 Actinosynnema mirum DSM 43827 diguanylate cyclase/phosphodiesterase YP_003102812.1 6134080 D 446462 CDS YP_003102813.1 256379153 8329348 6135991..6137112 1 NC_013093.1 PFAM: glutamate--cysteine ligase GCS2; KEGG: jan:Jann_1911 carboxylate-amine ligase; glutamate--cysteine ligase GCS2 6137112 8329348 Amir_5146 Actinosynnema mirum DSM 43827 glutamate--cysteine ligase GCS2 YP_003102813.1 6135991 D 446462 CDS YP_003102814.1 256379154 8329349 6137184..6137597 1 NC_013093.1 PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: bph:Bphy_4760 CBS domain-containing protein; signal transduction protein with CBS domains 6137597 8329349 Amir_5147 Actinosynnema mirum DSM 43827 signal transduction protein with CBS domains YP_003102814.1 6137184 D 446462 CDS YP_003102815.1 256379155 8329350 complement(6137682..6138077) 1 NC_013093.1 PFAM: protein of unknown function DUF59; KEGG: eli:ELI_12745 metal-sulfur cluster biosynthetic enzyme; hypothetical protein 6138077 8329350 Amir_5148 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102815.1 6137682 R 446462 CDS YP_003102816.1 256379156 8329351 complement(6138074..6138517) 1 NC_013093.1 TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: bsu:BSU32680 hypothetical protein; SUF system FeS assembly protein, NifU family 6138517 8329351 Amir_5149 Actinosynnema mirum DSM 43827 SUF system FeS assembly protein, NifU family YP_003102816.1 6138074 R 446462 CDS YP_003102817.1 256379157 8329352 complement(6138517..6139794) 1 NC_013093.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; KEGG: acr:Acry_2269 SufS subfamily cysteine desulfurase; SufS subfamily cysteine desulfurase 6139794 8329352 Amir_5150 Actinosynnema mirum DSM 43827 SufS subfamily cysteine desulfurase YP_003102817.1 6138517 R 446462 CDS YP_003102818.1 256379158 8329353 complement(6139858..6140631) 1 NC_013093.1 KEGG: bat:BAS4851 ABC transporter, ATP-binding protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; SMART: ATPase AAA; FeS assembly ATPase SufC 6140631 8329353 Amir_5151 Actinosynnema mirum DSM 43827 FeS assembly ATPase SufC YP_003102818.1 6139858 R 446462 CDS YP_003102819.1 256379159 8329354 complement(6140669..6140995) 1 NC_013093.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: bmn:BMA10247_A0236 aromatic-ring- hydroxylating dioxygenase, ferredoxin subunit; Rieske (2Fe-2S) domain-containing protein 6140995 8329354 Amir_5152 Actinosynnema mirum DSM 43827 Rieske (2Fe-2S) domain-containing protein YP_003102819.1 6140669 R 446462 CDS YP_003102820.1 256379160 8329355 complement(6140992..6142164) 1 NC_013093.1 TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: mxa:MXAN_1155 FeS assembly protein SufD; FeS assembly protein SufD 6142164 8329355 Amir_5153 Actinosynnema mirum DSM 43827 FeS assembly protein SufD YP_003102820.1 6140992 R 446462 CDS YP_003102821.1 256379161 8329356 complement(6142166..6143611) 1 NC_013093.1 TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: bcz:BCZK4703 iron-regulated ABC transporter; FeS assembly protein SufB 6143611 8329356 Amir_5154 Actinosynnema mirum DSM 43827 FeS assembly protein SufB YP_003102821.1 6142166 R 446462 CDS YP_003102822.1 256379162 8329357 complement(6143608..6144324) 1 NC_013093.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: ypk:y4095 hypothetical protein; transcriptional regulator 6144324 8329357 Amir_5155 Actinosynnema mirum DSM 43827 transcriptional regulator YP_003102822.1 6143608 R 446462 CDS YP_003102823.1 256379163 8329358 6144522..6145559 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_0865 oxidoreductase, short chain dehydrogenase/reductase family; short-chain dehydrogenase/reductase SDR 6145559 8329358 Amir_5156 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003102823.1 6144522 D 446462 CDS YP_003102824.1 256379164 8329359 6145570..6146151 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: msl:Msil_3313 transcriptional regulator, TetR family; TetR family transcriptional regulator 6146151 8329359 Amir_5157 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102824.1 6145570 D 446462 CDS YP_003102825.1 256379165 8329360 6146256..6147839 1 NC_013093.1 KEGG: met:M446_4899 hypothetical protein; hypothetical protein 6147839 8329360 Amir_5158 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102825.1 6146256 D 446462 CDS YP_003102826.1 256379166 8329361 6147996..6151958 1 NC_013093.1 PFAM: Patatin; KEGG: bpm:BURPS1710b_1675 patatin family phospholipase; patatin 6151958 8329361 Amir_5159 Actinosynnema mirum DSM 43827 patatin YP_003102826.1 6147996 D 446462 CDS YP_003102827.1 256379167 8329362 complement(6151901..6154303) 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: lpc:LPC_1061 glycosyltransferase; group 1 glycosyl transferase 6154303 8329362 Amir_5160 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003102827.1 6151901 R 446462 CDS YP_003102828.1 256379168 8329363 complement(6154300..6154911) 1 NC_013093.1 KEGG: dvm:DvMF_2468 molybdopterin-containing oxidoreductase membrane anchor subunit; hypothetical protein 6154911 8329363 Amir_5161 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102828.1 6154300 R 446462 CDS YP_003102829.1 256379169 8329364 6155048..6155986 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mxa:MXAN_1597 ABC transporter, ATP-binding protein; ABC transporter 6155986 8329364 Amir_5162 Actinosynnema mirum DSM 43827 ABC transporter YP_003102829.1 6155048 D 446462 CDS YP_003102830.1 256379170 8329365 6155983..6156756 1 NC_013093.1 PFAM: ABC transporter; KEGG: scl:sce5572 integral membrane transport protein; ABC transporter 6156756 8329365 Amir_5163 Actinosynnema mirum DSM 43827 ABC transporter YP_003102830.1 6155983 D 446462 CDS YP_003102831.1 256379171 8329366 6156972..6157802 1 NC_013093.1 KEGG: Sfrs15; splicing factor, arginine/serine-rich 15; hypothetical protein 6157802 8329366 Amir_5164 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102831.1 6156972 D 446462 CDS YP_003102832.1 256379172 8329367 6157799..6158122 1 NC_013093.1 hypothetical protein 6158122 8329367 Amir_5165 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102832.1 6157799 D 446462 CDS YP_003102833.1 256379173 8329368 6158126..6159247 1 NC_013093.1 KEGG: pfo:Pfl01_4833 chemotaxis sensory transducer; hypothetical protein 6159247 8329368 Amir_5166 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102833.1 6158126 D 446462 CDS YP_003102834.1 256379174 8329369 6159247..6160092 1 NC_013093.1 hypothetical protein 6160092 8329369 Amir_5167 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102834.1 6159247 D 446462 CDS YP_003102835.1 256379175 8329370 6160290..6161258 1 NC_013093.1 PFAM: cytochrome oxidase assembly; KEGG: noc:Noc_3040 cytochrome oxidase assembly; cytochrome oxidase assembly 6161258 8329370 Amir_5168 Actinosynnema mirum DSM 43827 cytochrome oxidase assembly YP_003102835.1 6160290 D 446462 CDS YP_003102836.1 256379176 8329371 complement(6161201..6161659) 1 NC_013093.1 SMART: regulatory protein ArsR; KEGG: scl:sce6114 hypothetical protein; ArsR family transcriptional regulator 6161659 8329371 Amir_5169 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003102836.1 6161201 R 446462 CDS YP_003102837.1 256379177 8329372 complement(6161792..6162595) 1 NC_013093.1 PFAM: protein of unknown function DUF742; KEGG: Hypothetical protein CBG22207; hypothetical protein 6162595 8329372 Amir_5170 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102837.1 6161792 R 446462 CDS YP_003102838.1 256379178 8329373 complement(6162606..6163049) 1 NC_013093.1 PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_0367 roadblock/LC7 family protein; Roadblock/LC7 family protein 6163049 8329373 Amir_5171 Actinosynnema mirum DSM 43827 Roadblock/LC7 family protein YP_003102838.1 6162606 R 446462 CDS YP_003102839.1 256379179 8329374 complement(6163046..6166117) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: rpe:RPE_2275 peptidase C14, caspase catalytic subunit P20; sensor with HAMP domain 6166117 8329374 Amir_5172 Actinosynnema mirum DSM 43827 sensor with HAMP domain YP_003102839.1 6163046 R 446462 CDS YP_003102840.1 256379180 8329375 6166459..6166878 1 NC_013093.1 PFAM: protein of unknown function DUF485; KEGG: sus:Acid_0924 hypothetical protein; hypothetical protein 6166878 8329375 Amir_5173 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102840.1 6166459 D 446462 CDS YP_003102841.1 256379181 8329376 6166878..6168455 1 NC_013093.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: dvm:DvMF_0315 SSS sodium solute transporter superfamily; SSS sodium solute transporter superfamily protein 6168455 8329376 Amir_5174 Actinosynnema mirum DSM 43827 SSS sodium solute transporter superfamily protein YP_003102841.1 6166878 D 446462 CDS YP_003102842.1 256379182 8329377 complement(6168549..6169409) 1 NC_013093.1 KEGG: tmz:Tmz1t_1794 hypothetical protein; hypothetical protein 6169409 8329377 Amir_5175 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102842.1 6168549 R 446462 CDS YP_003102843.1 256379183 8329378 complement(6169406..6169693) 1 NC_013093.1 hypothetical protein 6169693 8329378 Amir_5176 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102843.1 6169406 R 446462 CDS YP_003102844.1 256379184 8329379 6169708..6171339 1 NC_013093.1 PFAM: protein of unknown function DUF885; KEGG: mxa:MXAN_0186 lipoprotein; hypothetical protein 6171339 8329379 Amir_5177 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102844.1 6169708 D 446462 CDS YP_003102845.1 256379185 8329380 6171538..6172509 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bte:BTH_II0233 quinone oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 6172509 8329380 Amir_5178 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003102845.1 6171538 D 446462 CDS YP_003102846.1 256379186 8329381 complement(6172660..6173247) 1 NC_013093.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: scl:sce3796 FKBP-type peptidyl-prolyl cis- trans isomerase; FKBP-type peptidylprolyl isomerase 6173247 8329381 Amir_5179 Actinosynnema mirum DSM 43827 FKBP-type peptidylprolyl isomerase YP_003102846.1 6172660 R 446462 CDS YP_003102847.1 256379187 8329382 6173453..6174460 1 NC_013093.1 hypothetical protein 6174460 8329382 Amir_5180 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102847.1 6173453 D 446462 CDS YP_003102848.1 256379188 8329383 6174467..6175114 1 NC_013093.1 hypothetical protein 6175114 8329383 Amir_5181 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102848.1 6174467 D 446462 CDS YP_003102849.1 256379189 8329384 6175382..6176020 1 NC_013093.1 KEGG: bsu:BSU21890 hypothetical protein; hypothetical protein 6176020 8329384 Amir_5182 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102849.1 6175382 D 446462 CDS YP_003102850.1 256379190 8329385 6176139..6176789 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: mno:Mnod_5360 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 6176789 8329385 Amir_5183 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102850.1 6176139 D 446462 CDS YP_003102851.1 256379191 8329386 6177402..6177782 1 NC_013093.1 KEGG: eca:ECA0122 hypothetical protein; hypothetical protein 6177782 8329386 Amir_5184 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102851.1 6177402 D 446462 CDS YP_003102852.1 256379192 8329387 complement(6177895..6178818) 1 NC_013093.1 TIGRFAM: protoheme IX farnesyltransferase; PFAM: UbiA prenyltransferase; KEGG: rce:RC1_3632 protoheme IX farnesyltransferase; protoheme IX farnesyltransferase 6178818 8329387 Amir_5185 Actinosynnema mirum DSM 43827 protoheme IX farnesyltransferase YP_003102852.1 6177895 R 446462 CDS YP_003102853.1 256379193 8329388 6179098..6181191 1 NC_013093.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 6181191 8329388 Amir_5186 Actinosynnema mirum DSM 43827 transketolase YP_003102853.1 6179098 D 446462 CDS YP_003102854.1 256379194 8329389 6181224..6182336 1 NC_013093.1 TIGRFAM: transaldolase; PFAM: transaldolase; KEGG: aba:Acid345_2810 bifunctional transaldolase/phosoglucose isomerase; transaldolase 6182336 8329389 Amir_5187 Actinosynnema mirum DSM 43827 transaldolase YP_003102854.1 6181224 D 446462 CDS YP_003102855.1 256379195 8329390 6182339..6183958 1 NC_013093.1 PFAM: phosphoglucose isomerase (PGI); KEGG: mno:Mnod_7445 transaldolase; phosphoglucose isomerase (PGI) 6183958 8329390 Amir_5188 Actinosynnema mirum DSM 43827 phosphoglucose isomerase (PGI) YP_003102855.1 6182339 D 446462 CDS YP_003102856.1 256379196 8329391 6183955..6185496 1 NC_013093.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 6185496 8329391 Amir_5189 Actinosynnema mirum DSM 43827 glucose-6-phosphate 1-dehydrogenase YP_003102856.1 6183955 D 446462 CDS YP_003102857.1 256379197 8329392 6185493..6186632 1 NC_013093.1 TIGRFAM: OpcA protein; KEGG: sus:Acid_5280 glucose-6-P dehydrogenase subunit-like protein; OpcA protein 6186632 8329392 Amir_5190 Actinosynnema mirum DSM 43827 OpcA protein YP_003102857.1 6185493 D 446462 CDS YP_003102858.1 256379198 8329393 6186629..6187408 1 NC_013093.1 TIGRFAM: 6-phosphogluconolactonase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: gdi:GDI0291 6-phosphogluconolactonase; 6-phosphogluconolactonase 6187408 8329393 Amir_5191 Actinosynnema mirum DSM 43827 6-phosphogluconolactonase YP_003102858.1 6186629 D 446462 CDS YP_003102859.1 256379199 8329394 6187858..6189195 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 6189195 8329394 Amir_5192 Actinosynnema mirum DSM 43827 histidine kinase YP_003102859.1 6187858 D 446462 CDS YP_003102860.1 256379200 8329395 complement(6189582..6190907) 1 NC_013093.1 KEGG: GI19648 gene product from transcript GI19648- RA; hypothetical protein 6190907 8329395 Amir_5193 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102860.1 6189582 R 446462 CDS YP_003102861.1 256379201 8329396 6190952..6191893 1 NC_013093.1 KEGG: YALI0C10450p; hypothetical protein 6191893 8329396 Amir_5194 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102861.1 6190952 D 446462 CDS YP_003102862.1 256379202 8329397 complement(6191977..6192273) 1 NC_013093.1 hypothetical protein 6192273 8329397 Amir_5195 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102862.1 6191977 R 446462 CDS YP_003102863.1 256379203 8329398 complement(6192373..6192606) 1 NC_013093.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: pne:Pnec_0820 preprotein translocase, SecG subunit; preprotein translocase subunit SecG 6192606 secG 8329398 secG Actinosynnema mirum DSM 43827 preprotein translocase subunit SecG YP_003102863.1 6192373 R 446462 CDS YP_003102864.1 256379204 8329399 complement(6192700..6193485) 1 NC_013093.1 KEGG: bsu:BSU33920 triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; triosephosphate isomerase 6193485 8329399 Amir_5197 Actinosynnema mirum DSM 43827 triosephosphate isomerase YP_003102864.1 6192700 R 446462 CDS YP_003102865.1 256379205 8329400 complement(6193487..6194653) 1 NC_013093.1 PFAM: phosphoglycerate kinase; KEGG: bsu:BSU33930 phosphoglycerate kinase; phosphoglycerate kinase 6194653 8329400 Amir_5198 Actinosynnema mirum DSM 43827 phosphoglycerate kinase YP_003102865.1 6193487 R 446462 CDS YP_003102866.1 256379206 8329401 complement(6194673..6195677) 1 NC_013093.1 KEGG: bha:BH3560 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase, type I 6195677 8329401 Amir_5199 Actinosynnema mirum DSM 43827 glyceraldehyde-3-phosphate dehydrogenase, type I YP_003102866.1 6194673 R 446462 CDS YP_003102867.1 256379207 8329402 complement(6196043..6197023) 1 NC_013093.1 KEGG: PHC10; cell wall protein pherophorin-C10; hypothetical protein 6197023 8329402 Amir_5200 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102867.1 6196043 R 446462 CDS YP_003102868.1 256379208 8329403 complement(6197113..6197244) 1 NC_013093.1 hypothetical protein 6197244 8329403 Amir_5201 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102868.1 6197113 R 446462 CDS YP_003102869.1 256379209 8329404 complement(6197329..6198534) 1 NC_013093.1 KEGG: scl:sce6476 hypothetical protein; hypothetical protein 6198534 8329404 Amir_5202 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102869.1 6197329 R 446462 CDS YP_003102870.1 256379210 8329405 complement(6198662..6199648) 1 NC_013093.1 PFAM: protein of unknown function DUF199; KEGG: bsu:BSU34750 hypothetical protein; hypothetical protein 6199648 8329405 Amir_5203 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102870.1 6198662 R 446462 CDS YP_003102871.1 256379211 8329406 complement(6199639..6200691) 1 NC_013093.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: afw:Anae109_2613 protein of unknown function UPF0052 and CofD; hypothetical protein 6200691 8329406 Amir_5204 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102871.1 6199639 R 446462 CDS YP_003102872.1 256379212 8329407 complement(6200688..6201575) 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: afw:Anae109_0152 hypothetical protein; hypothetical protein 6201575 8329407 Amir_5205 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102872.1 6200688 R 446462 CDS YP_003102873.1 256379213 8329408 complement(6201572..6203521) 1 NC_013093.1 KEGG: tgr:Tgr7_1907 excinuclease ABC subunit C; TIGRFAM: excinuclease ABC, C subunit; PFAM: excinuclease ABC C subunit domain protein; Excinuclease ABC C subunit domain protein; helix-hairpin- helix motif; UvrB/UvrC protein; SMART: Excinuclease ABC C subunit domain protein; Helix-hairpin-helix DNA-binding class 1; excinuclease ABC subunit C 6203521 8329408 Amir_5206 Actinosynnema mirum DSM 43827 excinuclease ABC subunit C YP_003102873.1 6201572 R 446462 CDS YP_003102874.1 256379214 8329409 complement(6203863..6204378) 1 NC_013093.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: bxe:Bxe_B1329 dioxygenase, ferredoxin reductase component; Rieske (2Fe-2S) domain-containing protein 6204378 8329409 Amir_5207 Actinosynnema mirum DSM 43827 Rieske (2Fe-2S) domain-containing protein YP_003102874.1 6203863 R 446462 CDS YP_003102875.1 256379215 8329410 complement(6204629..6205039) 1 NC_013093.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: xcv:XCV3420 Rieske 2Fe-2S family protein; Rieske (2Fe-2S) domain-containing protein 6205039 8329410 Amir_5208 Actinosynnema mirum DSM 43827 Rieske (2Fe-2S) domain-containing protein YP_003102875.1 6204629 R 446462 CDS YP_003102876.1 256379216 8329411 complement(6205919..6206410) 1 NC_013093.1 hypothetical protein 6206410 8329411 Amir_5209 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102876.1 6205919 R 446462 CDS YP_003102877.1 256379217 8329412 6206655..6208247 1 NC_013093.1 XRE family transcriptional regulator 6208247 8329412 Amir_5210 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102877.1 6206655 D 446462 CDS YP_003102878.1 256379218 8329413 6208247..6208744 1 NC_013093.1 KEGG: bxe:Bxe_C1257 hypothetical protein; hypothetical protein 6208744 8329413 Amir_5211 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102878.1 6208247 D 446462 CDS YP_003102879.1 256379219 8329414 6208808..6209761 1 NC_013093.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: scl:sce5223 DeoR family transcriptional regulator; Helix-turn-helix type 11 domain-containing protein 6209761 8329414 Amir_5212 Actinosynnema mirum DSM 43827 Helix-turn-helix type 11 domain-containing protein YP_003102879.1 6208808 D 446462 CDS YP_003102880.1 256379220 8329415 complement(6209768..6210709) 1 NC_013093.1 hypothetical protein 6210709 8329415 Amir_5213 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102880.1 6209768 R 446462 CDS YP_003102881.1 256379221 8329416 complement(6210709..6211206) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: pca:Pcar_3124 RNA polymerase, sigma-E factor; ECF subfamily RNA polymerase sigma-24 subunit 6211206 8329416 Amir_5214 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102881.1 6210709 R 446462 CDS YP_003102882.1 256379222 8329417 complement(6211360..6212712) 1 NC_013093.1 PFAM: peptidase M28; peptidase M20; KEGG: bcy:Bcer98_3876 peptidase M28; peptidase M28 6212712 8329417 Amir_5215 Actinosynnema mirum DSM 43827 peptidase M28 YP_003102882.1 6211360 R 446462 CDS YP_003102883.1 256379223 8329418 complement(6212815..6213291) 1 NC_013093.1 hypothetical protein 6213291 8329418 Amir_5216 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102883.1 6212815 R 446462 CDS YP_003102884.1 256379224 8329419 complement(6213288..6213770) 1 NC_013093.1 KEGG: dds:Ddes_1621 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; 6,7-dimethyl-8-ribityllumazine synthase 6213770 8329419 Amir_5217 Actinosynnema mirum DSM 43827 6,7-dimethyl-8-ribityllumazine synthase YP_003102884.1 6213288 R 446462 CDS YP_003102885.1 256379225 8329420 complement(6213767..6215020) 1 NC_013093.1 KEGG: ATGCH; ATGCH (ARABIDOPSIS THALIANA GTP CYCLOHYDROLASE II); 3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP cyclohydrolase II; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase 6215020 8329420 Amir_5218 Actinosynnema mirum DSM 43827 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_003102885.1 6213767 R 446462 CDS YP_003102886.1 256379226 8329421 complement(6215017..6215655) 1 NC_013093.1 TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: hap:HAPS_1135 riboflavin synthase subunit alpha; riboflavin synthase subunit alpha 6215655 8329421 Amir_5219 Actinosynnema mirum DSM 43827 riboflavin synthase subunit alpha YP_003102886.1 6215017 R 446462 CDS YP_003102887.1 256379227 8329422 complement(6215763..6216413) 1 NC_013093.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 6216413 8329422 Amir_5220 Actinosynnema mirum DSM 43827 ribulose-phosphate 3-epimerase YP_003102887.1 6215763 R 446462 CDS YP_003102888.1 256379228 8329423 complement(6216688..6218796) 1 NC_013093.1 KEGG: acp:A2cp1_3940 hypothetical protein; hypothetical protein 6218796 8329423 Amir_5221 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102888.1 6216688 R 446462 CDS YP_003102889.1 256379229 8329424 complement(6218903..6219448) 1 NC_013093.1 PFAM: flavoprotein; KEGG: xau:Xaut_0078 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; flavoprotein 6219448 8329424 Amir_5222 Actinosynnema mirum DSM 43827 flavoprotein YP_003102889.1 6218903 R 446462 CDS YP_003102890.1 256379230 8329425 complement(6219516..6220952) 1 NC_013093.1 PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: ade:Adeh_3970 NusB/RsmB/TIM44 family protein; Fmu (Sun) domain-containing protein 6220952 8329425 Amir_5223 Actinosynnema mirum DSM 43827 Fmu (Sun) domain-containing protein YP_003102890.1 6219516 R 446462 CDS YP_003102891.1 256379231 8329426 complement(6220949..6221881) 1 NC_013093.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: mca:MCA2844 methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 6221881 8329426 Amir_5224 Actinosynnema mirum DSM 43827 methionyl-tRNA formyltransferase YP_003102891.1 6220949 R 446462 CDS YP_003102892.1 256379232 8329427 complement(6221883..6222428) 1 NC_013093.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 6222428 def 8329427 def Actinosynnema mirum DSM 43827 peptide deformylase YP_003102892.1 6221883 R 446462 CDS YP_003102893.1 256379233 8329428 6223044..6223148 1 NC_013093.1 hypothetical protein 6223148 8329428 Amir_5226 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102893.1 6223044 D 446462 CDS YP_003102894.1 256379234 8329429 complement(6223159..6223293) 1 NC_013093.1 hypothetical protein 6223293 8329429 Amir_5227 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102894.1 6223159 R 446462 CDS YP_003102895.1 256379235 8329430 6223507..6224046 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: pla:Plav_1868 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit 6224046 8329430 Amir_5228 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102895.1 6223507 D 446462 CDS YP_003102896.1 256379236 8329431 6224515..6225216 1 NC_013093.1 hypothetical protein 6225216 8329431 Amir_5229 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102896.1 6224515 D 446462 CDS YP_003102897.1 256379237 8329432 6225194..6225622 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; KEGG: pzu:PHZ_c1529 RNA polymerase sigma-70 factor,ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 6225622 8329432 Amir_5230 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003102897.1 6225194 D 446462 CDS YP_003102898.1 256379238 8329433 6225619..6226830 1 NC_013093.1 hypothetical protein 6226830 8329433 Amir_5231 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102898.1 6225619 D 446462 CDS YP_003102899.1 256379239 8329434 complement(6226930..6228747) 1 NC_013093.1 KEGG: scl:sce1211 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; gamma-glutamyltransferase 6228747 8329434 Amir_5232 Actinosynnema mirum DSM 43827 gamma-glutamyltransferase YP_003102899.1 6226930 R 446462 CDS YP_003102900.1 256379240 8329435 6228957..6229259 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6229259 8329435 Amir_5233 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102900.1 6228957 D 446462 CDS YP_003102901.1 256379241 8329436 complement(6229267..6231264) 1 NC_013093.1 KEGG: bav:BAV3210 primosomal protein N'; Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein 6231264 8329436 Amir_5234 Actinosynnema mirum DSM 43827 Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein YP_003102901.1 6229267 R 446462 CDS YP_003102902.1 256379242 8329437 complement(6231334..6232536) 1 NC_013093.1 KEGG: bha:BH3300 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 6232536 8329437 Amir_5235 Actinosynnema mirum DSM 43827 S-adenosylmethionine synthetase YP_003102902.1 6231334 R 446462 CDS YP_003102903.1 256379243 8329438 complement(6232619..6233887) 1 NC_013093.1 KEGG: acp:A2cp1_1587 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase 6233887 8329438 Amir_5236 Actinosynnema mirum DSM 43827 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase YP_003102903.1 6232619 R 446462 CDS YP_003102904.1 256379244 8329439 complement(6233884..6234162) 1 NC_013093.1 TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; KEGG: rma:Rmag_0405 DNA-directed RNA polymerase, omega subunit; DNA-directed RNA polymerase subunit omega 6234162 8329439 Amir_5237 Actinosynnema mirum DSM 43827 DNA-directed RNA polymerase subunit omega YP_003102904.1 6233884 R 446462 CDS YP_003102905.1 256379245 8329440 complement(6234290..6234889) 1 NC_013093.1 KEGG: bcy:Bcer98_2523 guanylate kinase; TIGRFAM: guanylate kinase; PFAM: guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; guanylate kinase 6234889 8329440 Amir_5238 Actinosynnema mirum DSM 43827 guanylate kinase YP_003102905.1 6234290 R 446462 CDS YP_003102906.1 256379246 8329441 complement(6234886..6235203) 1 NC_013093.1 hypothetical protein 6235203 8329441 Amir_5239 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102906.1 6234886 R 446462 CDS YP_003102907.1 256379247 8329442 complement(6235512..6236330) 1 NC_013093.1 TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mxa:MXAN_5910 orotidine 5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 6236330 8329442 Amir_5240 Actinosynnema mirum DSM 43827 orotidine 5'-phosphate decarboxylase YP_003102907.1 6235512 R 446462 CDS YP_003102908.1 256379248 8329443 complement(6236327..6239626) 1 NC_013093.1 TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: carbamoyl-phosphate synthase L chain ATP- binding; RimK domain protein ATP-grasp; MGS domain protein; ATP-grasp domain protein; carbamoyl-phosphate synthetase large chain oligomerisation; carbamoyl- phosphate synthetase large chain domain protein; KEGG: gur:Gura_1864 carbamoyl-phosphate synthase, large subunit; carbamoyl-phosphate synthase, large subunit 6239626 8329443 Amir_5241 Actinosynnema mirum DSM 43827 carbamoyl-phosphate synthase, large subunit YP_003102908.1 6236327 R 446462 CDS YP_003102909.1 256379249 8329444 complement(6239628..6240740) 1 NC_013093.1 KEGG: smt:Smal_1811 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; carbamoyl-phosphate synthase, small subunit 6240740 8329444 Amir_5242 Actinosynnema mirum DSM 43827 carbamoyl-phosphate synthase, small subunit YP_003102909.1 6239628 R 446462 CDS YP_003102910.1 256379250 8329445 complement(6240737..6241228) 1 NC_013093.1 hypothetical protein 6241228 8329445 Amir_5243 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102910.1 6240737 R 446462 CDS YP_003102911.1 256379251 8329446 complement(6241225..6242526) 1 NC_013093.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 6242526 pyrC 8329446 pyrC Actinosynnema mirum DSM 43827 dihydroorotase YP_003102911.1 6241225 R 446462 CDS YP_003102912.1 256379252 8329447 complement(6242523..6243458) 1 NC_013093.1 TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: scl:sce3822 hypothetical protein; aspartate carbamoyltransferase 6243458 8329447 Amir_5245 Actinosynnema mirum DSM 43827 aspartate carbamoyltransferase YP_003102912.1 6242523 R 446462 CDS YP_003102913.1 256379253 8329448 complement(6243455..6244027) 1 NC_013093.1 PFAM: phosphoribosyltransferase; KEGG: gsu:GSU1270 pyrimidine regulatory protein pyrR; uracil phosphoribosyltransferase 6244027 8329448 Amir_5246 Actinosynnema mirum DSM 43827 uracil phosphoribosyltransferase YP_003102913.1 6243455 R 446462 CDS YP_003102914.1 256379254 8329449 6244286..6244774 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pzu:PHZ_c2067 transcriptional regulator, Cro/CI family; XRE family transcriptional regulator 6244774 8329449 Amir_5247 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003102914.1 6244286 D 446462 CDS YP_003102915.1 256379255 8329450 complement(6245175..6245594) 1 NC_013093.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44; KEGG: mxa:MXAN_4761 transcription antitermination factor NusB; NusB antitermination factor 6245594 8329450 Amir_5248 Actinosynnema mirum DSM 43827 NusB antitermination factor YP_003102915.1 6245175 R 446462 CDS YP_003102916.1 256379256 8329451 complement(6245596..6246159) 1 NC_013093.1 TIGRFAM: translation elongation factor P; PFAM: Elongation factor KOW domain protein; Elongation factor P; Elongation factor P/YeiP protein; KEGG: bha:BH2799 elongation factor P; translation elongation factor P 6246159 8329451 Amir_5249 Actinosynnema mirum DSM 43827 translation elongation factor P YP_003102916.1 6245596 R 446462 CDS YP_003102917.1 256379257 8329452 complement(6246215..6247312) 1 NC_013093.1 PFAM: peptidase M24; creatinase; KEGG: sus:Acid_7433 peptidase M24; peptidase M24 6247312 8329452 Amir_5250 Actinosynnema mirum DSM 43827 peptidase M24 YP_003102917.1 6246215 R 446462 CDS YP_003102918.1 256379258 8329453 complement(6247785..6249296) 1 NC_013093.1 KEGG: mrd:Mrad2831_3019 hypothetical protein; hypothetical protein 6249296 8329453 Amir_5251 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102918.1 6247785 R 446462 CDS YP_003102919.1 256379259 8329454 complement(6249782..6250222) 1 NC_013093.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 6250222 8329454 Amir_5252 Actinosynnema mirum DSM 43827 3-dehydroquinate dehydratase YP_003102919.1 6249782 R 446462 CDS YP_003102920.1 256379260 8329455 complement(6250219..6251325) 1 NC_013093.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 6251325 aroB 8329455 aroB Actinosynnema mirum DSM 43827 3-dehydroquinate synthase YP_003102920.1 6250219 R 446462 CDS YP_003102921.1 256379261 8329456 complement(6252277..6252792) 1 NC_013093.1 PFAM: shikimate kinase; KEGG: pen:PSEEN0334 shikimate kinase; shikimate kinase 6252792 8329456 Amir_5254 Actinosynnema mirum DSM 43827 shikimate kinase YP_003102921.1 6252277 R 446462 CDS YP_003102922.1 256379262 8329457 complement(6252789..6253988) 1 NC_013093.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 6253988 8329457 Amir_5255 Actinosynnema mirum DSM 43827 chorismate synthase YP_003102922.1 6252789 R 446462 CDS YP_003102923.1 256379263 8329458 complement(6254941..6255525) 1 NC_013093.1 PFAM: peptidase A24A prepilin type IV; KEGG: hha:Hhal_2022 prepilin peptidase; peptidase A24A prepilin type IV 6255525 8329458 Amir_5256 Actinosynnema mirum DSM 43827 peptidase A24A prepilin type IV YP_003102923.1 6254941 R 446462 CDS YP_003102924.1 256379264 8329459 complement(6255717..6256175) 1 NC_013093.1 TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: bsu:BSU39270 phosphotransferase system (PTS) beta-glucoside-specific enzyme IIBCA component; PTS system, glucose subfamily, IIA subunit 6256175 8329459 Amir_5257 Actinosynnema mirum DSM 43827 PTS system, glucose subfamily, IIA subunit YP_003102924.1 6255717 R 446462 CDS YP_003102925.1 256379265 8329460 complement(6256172..6256408) 1 NC_013093.1 PFAM: phosphotransferase system PTS EIIB protein; KEGG: esa:ESA_00528 hypothetical protein; phosphotransferase system PTS EIIB protein 6256408 8329460 Amir_5258 Actinosynnema mirum DSM 43827 phosphotransferase system PTS EIIB protein YP_003102925.1 6256172 R 446462 CDS YP_003102926.1 256379266 8329461 6256582..6257346 1 NC_013093.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bha:BH0419 GntR family transcriptional regulator; GntR family transcriptional regulator 6257346 8329461 Amir_5259 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003102926.1 6256582 D 446462 CDS YP_003102927.1 256379267 8329462 6257343..6258641 1 NC_013093.1 PFAM: phosphotransferase system EIIC; KEGG: bha:BH0422 PTS system, N-acetylglucosamine- specific enzyme II, ABC component; Protein-N(pi)-phosphohistidine--sugar phosphotransferase 6258641 8329462 Amir_5260 Actinosynnema mirum DSM 43827 Protein-N(pi)-phosphohistidine--sugar phosphotransferase YP_003102927.1 6257343 D 446462 CDS YP_003102928.1 256379268 8329463 6258660..6258932 1 NC_013093.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: aeh:Mlg_2234 HPr family phosphocarrier protein; phosphotransferase system, phosphocarrier protein HPr 6258932 8329463 Amir_5261 Actinosynnema mirum DSM 43827 phosphotransferase system, phosphocarrier protein HPr YP_003102928.1 6258660 D 446462 CDS YP_003102929.1 256379269 8329464 complement(6259027..6259884) 1 NC_013093.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 6259884 aroE 8329464 aroE Actinosynnema mirum DSM 43827 shikimate 5-dehydrogenase YP_003102929.1 6259027 R 446462 CDS YP_003102930.1 256379270 8329465 complement(6259865..6261094) 1 NC_013093.1 PFAM: aminodeoxychorismate lyase; KEGG: gme:Gmet_3021 aminodeoxychorismate lyase; aminodeoxychorismate lyase 6261094 8329465 Amir_5263 Actinosynnema mirum DSM 43827 aminodeoxychorismate lyase YP_003102930.1 6259865 R 446462 CDS YP_003102931.1 256379271 8329466 complement(6261091..6261603) 1 NC_013093.1 PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; KEGG: bha:BH1269 hypothetical protein; Holliday junction resolvase YqgF 6261603 8329466 Amir_5264 Actinosynnema mirum DSM 43827 Holliday junction resolvase YqgF YP_003102931.1 6261091 R 446462 CDS YP_003102932.1 256379272 8329467 complement(6261590..6264262) 1 NC_013093.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 6264262 alaS 8329467 alaS Actinosynnema mirum DSM 43827 alanyl-tRNA synthetase YP_003102932.1 6261590 R 446462 CDS YP_003102933.1 256379273 8329468 complement(6264317..6264580) 1 NC_013093.1 hypothetical protein 6264580 8329468 Amir_5266 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102933.1 6264317 R 446462 CDS YP_003102934.1 256379274 8329469 complement(6264577..6264984) 1 NC_013093.1 hypothetical protein 6264984 8329469 Amir_5267 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102934.1 6264577 R 446462 CDS YP_003102935.1 256379275 8329470 6265231..6265353 1 NC_013093.1 hypothetical protein 6265353 8329470 Amir_5268 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102935.1 6265231 D 446462 CDS YP_003102936.1 256379276 8329471 6265354..6266541 1 NC_013093.1 PFAM: cupin; SMART: transcription factor jumonji jmjC domain protein; KEGG: jan:Jann_0385 cupin 4; cupin 6266541 8329471 Amir_5269 Actinosynnema mirum DSM 43827 cupin YP_003102936.1 6265354 D 446462 CDS YP_003102937.1 256379277 8329472 6266592..6267536 1 NC_013093.1 PFAM: sucraseferredoxin; KEGG: hch:HCH_03459 hypothetical protein; sucraseferredoxin 6267536 8329472 Amir_5270 Actinosynnema mirum DSM 43827 sucraseferredoxin YP_003102937.1 6266592 D 446462 CDS YP_003102938.1 256379278 8329473 complement(6267852..6268616) 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: sfu:Sfum_2834 methyltransferase type 12; type 12 methyltransferase 6268616 8329473 Amir_5271 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003102938.1 6267852 R 446462 CDS YP_003102939.1 256379279 8329474 complement(6268687..6270033) 1 NC_013093.1 PFAM: ATPase AAA; magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: gsu:GSU2067 recombination factor protein RarA; recombination factor protein RarA 6270033 8329474 Amir_5272 Actinosynnema mirum DSM 43827 recombination factor protein RarA YP_003102939.1 6268687 R 446462 CDS YP_003102940.1 256379280 8329475 6270146..6270784 1 NC_013093.1 KEGG: hypothetical protein; K00876 uridine kinase; uridine kinase-like protein 6270784 8329475 Amir_5273 Actinosynnema mirum DSM 43827 uridine kinase-like protein YP_003102940.1 6270146 D 446462 CDS YP_003102941.1 256379281 8329476 6271178..6273661 1 NC_013093.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: scl:sce4364 ATP-dependent helicase; DEAD/DEAH box helicase domain-containing protein 6273661 8329476 Amir_5274 Actinosynnema mirum DSM 43827 DEAD/DEAH box helicase domain-containing protein YP_003102941.1 6271178 D 446462 CDS YP_003102942.1 256379282 8329477 6273904..6276873 1 NC_013093.1 PFAM: transcriptional activator domain; TPR repeat- containing protein; NB-ARC domain protein; transcriptional regulator domain protein; SMART: ATPase AAA; hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator 6276873 8329477 Amir_5275 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003102942.1 6273904 D 446462 CDS YP_003102943.1 256379283 8329478 complement(6277215..6277832) 1 NC_013093.1 PFAM: transglycosylase domain protein; peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: ade:Adeh_2701 peptidoglycan-binding LysM; transglycosylase domain-containing protein 6277832 8329478 Amir_5276 Actinosynnema mirum DSM 43827 transglycosylase domain-containing protein YP_003102943.1 6277215 R 446462 CDS YP_003102944.1 256379284 8329479 6278228..6278500 1 NC_013093.1 hypothetical protein 6278500 8329479 Amir_5277 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102944.1 6278228 D 446462 CDS YP_003102945.1 256379285 8329480 6278537..6279382 1 NC_013093.1 PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; KEGG: rpi:Rpic_1227 two component transcriptional regulator, LytTR family; LytTR family two component transcriptional regulator 6279382 8329480 Amir_5278 Actinosynnema mirum DSM 43827 LytTR family two component transcriptional regulator YP_003102945.1 6278537 D 446462 CDS YP_003102946.1 256379286 8329481 6279379..6279813 1 NC_013093.1 PFAM: protein of unknown function DUF485; hypothetical protein 6279813 8329481 Amir_5279 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102946.1 6279379 D 446462 CDS YP_003102947.1 256379287 8329482 6279810..6281531 1 NC_013093.1 PFAM: Na+/solute symporter; KEGG: ade:Adeh_3696 SSS family solute/sodium (Na+) symporter; Na+/solute symporter 6281531 8329482 Amir_5280 Actinosynnema mirum DSM 43827 Na+/solute symporter YP_003102947.1 6279810 D 446462 CDS YP_003102948.1 256379288 8329483 6281528..6282703 1 NC_013093.1 PFAM: histidine kinase internal region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: gme:Gmet_2698 histidine kinase internal region; signal transduction histidine kinase LytS 6282703 8329483 Amir_5281 Actinosynnema mirum DSM 43827 signal transduction histidine kinase LytS YP_003102948.1 6281528 D 446462 CDS YP_003102949.1 256379289 8329484 complement(6282803..6283177) 1 NC_013093.1 KEGG: rle:RL1216 hypothetical protein; hypothetical protein 6283177 8329484 Amir_5282 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102949.1 6282803 R 446462 CDS YP_003102950.1 256379290 8329485 6283261..6283815 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rlt:Rleg2_5162 transcriptional regulator, TetR family; TetR family transcriptional regulator 6283815 8329485 Amir_5283 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102950.1 6283261 D 446462 CDS YP_003102951.1 256379291 8329486 complement(6283907..6284491) 1 NC_013093.1 KEGG: bvi:Bcep1808_7569 transposase and inactivated derivatives-like protein; hypothetical protein 6284491 8329486 Amir_5284 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102951.1 6283907 R 446462 CDS YP_003102952.1 256379292 8329487 6284674..6285519 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: scl:sce5059 metallophosphoesterase; metallophosphoesterase 6285519 8329487 Amir_5285 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003102952.1 6284674 D 446462 CDS YP_003102953.1 256379293 8329488 6285516..6286172 1 NC_013093.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: gdi:GDI2832 phosphopantetheinyl transferase PptA; 4'-phosphopantetheinyl transferase 6286172 8329488 Amir_5286 Actinosynnema mirum DSM 43827 4'-phosphopantetheinyl transferase YP_003102953.1 6285516 D 446462 CDS YP_003102954.1 256379294 8329489 6286242..6287723 1 NC_013093.1 KEGG: swd:Swoo_0692 CBS domain-containing protein; CBS domain-containing protein 6287723 8329489 Amir_5287 Actinosynnema mirum DSM 43827 CBS domain-containing protein YP_003102954.1 6286242 D 446462 CDS YP_003102955.1 256379295 8329490 6287965..6289797 1 NC_013093.1 PFAM: hypothetical protein; KEGG: ecw:EcE24377A_3363 hypothetical protein; hypothetical protein 6289797 8329490 Amir_5288 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102955.1 6287965 D 446462 CDS YP_003102956.1 256379296 8329491 complement(6290127..6290963) 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: spe:Spro_3591 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 6290963 8329491 Amir_5289 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003102956.1 6290127 R 446462 CDS YP_003102957.1 256379297 8329492 6291107..6291490 1 NC_013093.1 PFAM: helix-turn-helix HxlR type; KEGG: transcriptional regulator protein; HxlR family transcriptional regulator 6291490 8329492 Amir_5290 Actinosynnema mirum DSM 43827 HxlR family transcriptional regulator YP_003102957.1 6291107 D 446462 CDS YP_003102958.1 256379298 8329493 complement(6291487..6291816) 1 NC_013093.1 hypothetical protein 6291816 8329493 Amir_5291 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102958.1 6291487 R 446462 CDS YP_003102959.1 256379299 8329494 complement(6292020..6292427) 1 NC_013093.1 hypothetical protein 6292427 8329494 Amir_5292 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102959.1 6292020 R 446462 CDS YP_003102960.1 256379300 8329495 complement(6292427..6293101) 1 NC_013093.1 KEGG: xcv:XCV1426 hypothetical protein; hypothetical protein 6293101 8329495 Amir_5293 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102960.1 6292427 R 446462 CDS YP_003102961.1 256379301 8329496 complement(6293171..6293743) 1 NC_013093.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 6293743 8329496 Amir_5294 Actinosynnema mirum DSM 43827 isopentenyl-diphosphate delta-isomerase YP_003102961.1 6293171 R 446462 CDS YP_003102962.1 256379302 8329497 complement(6293798..6294367) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mno:Mnod_1181 transcriptional regulator, TetR family; TetR family transcriptional regulator 6294367 8329497 Amir_5295 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102962.1 6293798 R 446462 CDS YP_003102963.1 256379303 8329498 6294444..6295292 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: rlt:Rleg2_1533 methyltransferase type 12; type 11 methyltransferase 6295292 8329498 Amir_5296 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003102963.1 6294444 D 446462 CDS YP_003102964.1 256379304 8329499 complement(6296166..6297128) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: bxe:Bxe_C1266 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 6297128 8329499 Amir_5297 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003102964.1 6296166 R 446462 CDS YP_003102965.1 256379305 8329500 6297234..6298163 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mmw:Mmwyl1_2496 helix-turn-helix domain- containing protein; AraC family transcriptional regulator 6298163 8329500 Amir_5298 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003102965.1 6297234 D 446462 CDS YP_003102966.1 256379306 8329501 6298310..6299056 1 NC_013093.1 hypothetical protein 6299056 8329501 Amir_5299 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102966.1 6298310 D 446462 CDS YP_003102967.1 256379307 8329502 6299047..6299460 1 NC_013093.1 hypothetical protein 6299460 8329502 Amir_5300 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102967.1 6299047 D 446462 CDS YP_003102968.1 256379308 8329503 complement(6299539..6300297) 1 NC_013093.1 KEGG: rpc:RPC_1516 hypothetical protein; hypothetical protein 6300297 8329503 Amir_5301 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102968.1 6299539 R 446462 CDS YP_003102969.1 256379309 8329504 complement(6300294..6301490) 1 NC_013093.1 KEGG: Trpm4; transient receptor potential cation channel, subfamily M, member 4; K04979 transient receptor potential cation channel, subfamily M, member 4; hypothetical protein 6301490 8329504 Amir_5302 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102969.1 6300294 R 446462 CDS YP_003102970.1 256379310 8329505 6301664..6303055 1 NC_013093.1 KEGG: xca:xccb100_0630 oxidoreductase; oxidoreductase 6303055 8329505 Amir_5303 Actinosynnema mirum DSM 43827 oxidoreductase YP_003102970.1 6301664 D 446462 CDS YP_003102971.1 256379311 8329506 6303143..6306604 1 NC_013093.1 SMART: ATPase AAA; KEGG: bbr:BB2829 hypothetical protein; ATPase AAA 6306604 8329506 Amir_5304 Actinosynnema mirum DSM 43827 ATPase AAA YP_003102971.1 6303143 D 446462 CDS YP_003102972.1 256379312 8329507 6307215..6307934 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: predicted protein; LPXTG-motif cell wall anchor domain-containing protein 6307934 8329507 Amir_5305 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003102972.1 6307215 D 446462 CDS YP_003102973.1 256379313 8329508 complement(6308101..6309090) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: scl:sce9297 zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 6309090 8329508 Amir_5306 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003102973.1 6308101 R 446462 CDS YP_003102974.1 256379314 8329509 complement(6309087..6309890) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: gdi:GDI2636 transporter protein; ABC transporter inner membrane protein 6309890 8329509 Amir_5307 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102974.1 6309087 R 446462 CDS YP_003102975.1 256379315 8329510 complement(6309887..6310771) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bam:Bamb_2642 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 6310771 8329510 Amir_5308 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003102975.1 6309887 R 446462 CDS YP_003102976.1 256379316 8329511 complement(6310806..6312149) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: bac:BamMC406_2511 extracellular solute- binding protein; family 1 extracellular solute-binding protein 6312149 8329511 Amir_5309 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003102976.1 6310806 R 446462 CDS YP_003102977.1 256379317 8329512 complement(6312231..6312992) 1 NC_013093.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: cak:Caul_0312 DeoR family transcriptional regulator; DeoR family transcriptional regulator 6312992 8329512 Amir_5310 Actinosynnema mirum DSM 43827 DeoR family transcriptional regulator YP_003102977.1 6312231 R 446462 CDS YP_003102978.1 256379318 8329513 complement(6313722..6314243) 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: cvi:CV_1553 enoyl-CoA hydratase; Enoyl-CoA hydratase/isomerase 6314243 8329513 Amir_5311 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003102978.1 6313722 R 446462 CDS YP_003102979.1 256379319 8329514 6314325..6314918 1 NC_013093.1 hypothetical protein 6314918 8329514 Amir_5312 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102979.1 6314325 D 446462 CDS YP_003102980.1 256379320 8329515 6314998..6318039 1 NC_013093.1 PFAM: lanthionine synthetase C family protein; KEGG: mxa:MXAN_6388 lanthionine synthetase C family protein; lanthionine synthetase C family protein 6318039 8329515 Amir_5313 Actinosynnema mirum DSM 43827 lanthionine synthetase C family protein YP_003102980.1 6314998 D 446462 CDS YP_003102981.1 256379321 8329516 6318092..6318322 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6318322 8329516 Amir_5314 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102981.1 6318092 D 446462 CDS YP_003102982.1 256379322 8329517 6319267..6322164 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: ade:Adeh_3289 SARP family transcriptional regulator; LuxR family transcriptional regulator 6322164 8329517 Amir_5315 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003102982.1 6319267 D 446462 CDS YP_003102983.1 256379323 8329518 6322251..6322949 1 NC_013093.1 PFAM: MOSC domain containing protein; KEGG: mex:Mext_4291 MOSC domain-containing protein; MOSC domain containing protein 6322949 8329518 Amir_5316 Actinosynnema mirum DSM 43827 MOSC domain containing protein YP_003102983.1 6322251 D 446462 CDS YP_003102984.1 256379324 8329519 complement(6322971..6323810) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: aba:Acid345_2253 aldo/keto reductase; aldo/keto reductase 6323810 8329519 Amir_5317 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003102984.1 6322971 R 446462 CDS YP_003102985.1 256379325 8329520 6324006..6324995 1 NC_013093.1 KEGG: rso:RS03172 signal peptide protein; hypothetical protein 6324995 8329520 Amir_5318 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102985.1 6324006 D 446462 CDS YP_003102986.1 256379326 8329522 complement(6325289..6327316) 1 NC_013093.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 6327316 8329522 Amir_5320 Actinosynnema mirum DSM 43827 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase YP_003102986.1 6325289 R 446462 CDS YP_003102987.1 256379327 8329523 6327469..6328749 1 NC_013093.1 PFAM: glycoside hydrolase family 16; Ricin B lectin; SMART: Ricin B lectin; KEGG: cja:CJA_2759 beta glucanase, , glu16F; glycoside hydrolase family protein 6328749 8329523 Amir_5321 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003102987.1 6327469 D 446462 CDS YP_003102988.1 256379328 8329524 complement(6328982..6329386) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6329386 8329524 Amir_5322 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102988.1 6328982 R 446462 CDS YP_003102989.1 256379329 8329525 complement(6329566..6332643) 1 NC_013093.1 PFAM: transcriptional activator domain; TPR repeat- containing protein; hypothetical protein; NB-ARC domain protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce6858 hypothetical protein; SARP family transcriptional regulator 6332643 8329525 Amir_5323 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003102989.1 6329566 R 446462 CDS YP_003102990.1 256379330 8329526 complement(6332870..6334897) 1 NC_013093.1 PFAM: acyltransferase 3; KEGG: mes:Meso_0485 acyltransferase 3; acyltransferase 3 6334897 8329526 Amir_5324 Actinosynnema mirum DSM 43827 acyltransferase 3 YP_003102990.1 6332870 R 446462 CDS YP_003102991.1 256379331 8329527 complement(6335295..6336191) 1 NC_013093.1 PFAM: protein of unknown function DUF75; KEGG: sfu:Sfum_3209 hypothetical protein; hypothetical protein 6336191 8329527 Amir_5325 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102991.1 6335295 R 446462 CDS YP_003102992.1 256379332 8329528 6336478..6338442 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: sat:SYN_01564 phospholipid-lipopolysaccharide ABC transporter; ABC transporter 6338442 8329528 Amir_5326 Actinosynnema mirum DSM 43827 ABC transporter YP_003102992.1 6336478 D 446462 CDS YP_003102993.1 256379333 8329529 6338502..6339098 1 NC_013093.1 KEGG: mch:Mchl_4435 methyl-accepting chemotaxis sensory transducer; hypothetical protein 6339098 8329529 Amir_5327 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102993.1 6338502 D 446462 CDS YP_003102994.1 256379334 8329530 6339241..6340680 1 NC_013093.1 KEGG: bxe:Bxe_B2117 CdaR family transcriptional regulator; PucR family transcriptional regulator 6340680 8329530 Amir_5328 Actinosynnema mirum DSM 43827 PucR family transcriptional regulator YP_003102994.1 6339241 D 446462 CDS YP_003102995.1 256379335 8329531 6340818..6341435 1 NC_013093.1 KEGG: aba:Acid345_2313 hypothetical protein; hypothetical protein 6341435 8329531 Amir_5329 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102995.1 6340818 D 446462 CDS YP_003102996.1 256379336 8329532 complement(6341614..6342186) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: ade:Adeh_2298 TetR family transcriptional regulator; TetR family transcriptional regulator 6342186 8329532 Amir_5330 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003102996.1 6341614 R 446462 CDS YP_003102997.1 256379337 8329533 6342287..6343165 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; dTDP-4-dehydrorhamnose reductase; KEGG: acp:A2cp1_1649 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 6343165 8329533 Amir_5331 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003102997.1 6342287 D 446462 CDS YP_003102998.1 256379338 8329534 6343268..6344176 1 NC_013093.1 PFAM: pseudouridine synthase; KEGG: pmy:Pmen_1453 pseudouridine synthase; pseudouridine synthase 6344176 8329534 Amir_5332 Actinosynnema mirum DSM 43827 pseudouridine synthase YP_003102998.1 6343268 D 446462 CDS YP_003102999.1 256379339 8329535 complement(6344234..6344854) 1 NC_013093.1 PFAM: protein of unknown function DUF305; KEGG: pag:PLES_26381 hypothetical protein; hypothetical protein 6344854 8329535 Amir_5333 Actinosynnema mirum DSM 43827 hypothetical protein YP_003102999.1 6344234 R 446462 CDS YP_003103000.1 256379340 8329536 complement(6344924..6345712) 1 NC_013093.1 PFAM: chitin-binding domain 3 protein; carbohydrate- binding family V/XII; SMART: carbohydrate-binding family V/XII; KEGG: hypothetical protein; chitin-binding domain 3 protein 6345712 8329536 Amir_5334 Actinosynnema mirum DSM 43827 chitin-binding domain 3 protein YP_003103000.1 6344924 R 446462 CDS YP_003103001.1 256379341 8329537 6346362..6346919 1 NC_013093.1 KEGG: glo:Glov_2382 alpha/beta hydrolase fold; hypothetical protein 6346919 8329537 Amir_5335 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103001.1 6346362 D 446462 CDS YP_003103002.1 256379342 8329538 complement(6347070..6348176) 1 NC_013093.1 PFAM: glycoside hydrolase family 19; KEGG: cja:CJA_0996 chitinase, , chi19A; chitinase 6348176 8329538 Amir_5336 Actinosynnema mirum DSM 43827 chitinase YP_003103002.1 6347070 R 446462 CDS YP_003103003.1 256379343 8329539 complement(6348544..6349017) 1 NC_013093.1 KEGG: hha:Hhal_2194 alcohol dehydrogenase, zinc- binding domain protein; hypothetical protein 6349017 8329539 Amir_5337 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103003.1 6348544 R 446462 CDS YP_003103004.1 256379344 8329540 complement(6349014..6349259) 1 NC_013093.1 KEGG: mlo:mll2594 quinone oxidoreductase; quinone oxidoreductase 6349259 8329540 Amir_5338 Actinosynnema mirum DSM 43827 quinone oxidoreductase YP_003103004.1 6349014 R 446462 CDS YP_003103005.1 256379345 8329541 6349434..6352061 1 NC_013093.1 PFAM: glycoside hydrolase family 9; cellulose- binding family II; glycoside hydrolase family 9 domain protein Ig domain protein; carbohydrate-binding CenC domain protein; SMART: cellulose-binding family II; KEGG: scl:sce2234 cellulase; glycoside hydrolase family protein 6352061 8329541 Amir_5339 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003103005.1 6349434 D 446462 CDS YP_003103006.1 256379346 8329542 complement(6352115..6352744) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: psa:PST_1446 oxidoreductase, short-chain dehydrogenase/reductase family; short-chain dehydrogenase/reductase SDR 6352744 8329542 Amir_5340 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003103006.1 6352115 R 446462 CDS YP_003103007.1 256379347 8329543 6352953..6354005 1 NC_013093.1 KEGG: sus:Acid_4466 beta-lactamase; hypothetical protein 6354005 8329543 Amir_5341 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103007.1 6352953 D 446462 CDS YP_003103008.1 256379348 8329544 6354255..6355676 1 NC_013093.1 TIGRFAM: Dyp-type peroxidase family; KEGG: aba:Acid345_1379 hypothetical protein; Dyp-type peroxidase family 6355676 8329544 Amir_5342 Actinosynnema mirum DSM 43827 Dyp-type peroxidase family YP_003103008.1 6354255 D 446462 CDS YP_003103009.1 256379349 8329545 6356553..6357593 1 NC_013093.1 KEGG: pzu:PHZ_c2158 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 6357593 8329545 Amir_5343 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003103009.1 6356553 D 446462 CDS YP_003103010.1 256379350 8329546 6357740..6359074 1 NC_013093.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: pde:Pden_3115 protein of unknown function DUF21; hypothetical protein 6359074 8329546 Amir_5344 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103010.1 6357740 D 446462 CDS YP_003103011.1 256379351 8329547 6359071..6360117 1 NC_013093.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; KEGG: hps:HPSH_07635 hypothetical protein; hypothetical protein 6360117 8329547 Amir_5345 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103011.1 6359071 D 446462 CDS YP_003103012.1 256379352 8329548 6360553..6361452 1 NC_013093.1 hypothetical protein 6361452 8329548 Amir_5346 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103012.1 6360553 D 446462 CDS YP_003103013.1 256379353 8329549 6361708..6363498 1 NC_013093.1 SMART: von Willebrand factor type A; KEGG: hypothetical protein; von Willebrand factor type A 6363498 8329549 Amir_5347 Actinosynnema mirum DSM 43827 von Willebrand factor type A YP_003103013.1 6361708 D 446462 CDS YP_003103014.1 256379354 8329551 6363847..6364035 1 NC_013093.1 hypothetical protein 6364035 8329551 Amir_5349 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103014.1 6363847 D 446462 CDS YP_003103015.1 256379355 8329552 complement(6364039..6364938) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: mlo:mlr0745 transcriptional regulator; ArsR family transcriptional regulator 6364938 8329552 Amir_5350 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003103015.1 6364039 R 446462 CDS YP_003103016.1 256379356 8329553 6364996..6366201 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: sil:SPO1430 antibiotic efflux protein; major facilitator superfamily protein 6366201 8329553 Amir_5351 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003103016.1 6364996 D 446462 CDS YP_003103017.1 256379357 8329554 complement(6366280..6369168) 1 NC_013093.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 6369168 8329554 Amir_5352 Actinosynnema mirum DSM 43827 glycine dehydrogenase YP_003103017.1 6366280 R 446462 CDS YP_003103018.1 256379358 8329555 complement(6369652..6370218) 1 NC_013093.1 SMART: regulatory protein MerR; KEGG: afw:Anae109_4225 MerR family transcriptional regulator; MerR family transcriptional regulator 6370218 8329555 Amir_5353 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003103018.1 6369652 R 446462 CDS YP_003103019.1 256379359 8329556 complement(6370603..6371076) 1 NC_013093.1 PFAM: protein of unknown function DUF151; KEGG: dal:Dalk_2411 protein of unknown function DUF151; hypothetical protein 6371076 8329556 Amir_5354 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103019.1 6370603 R 446462 CDS YP_003103020.1 256379360 8329557 complement(6371222..6372163) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: ade:Adeh_3310 zinc finger/thioredoxin; MerR family transcriptional regulator 6372163 8329557 Amir_5355 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003103020.1 6371222 R 446462 CDS YP_003103021.1 256379361 8329558 complement(6372197..6372649) 1 NC_013093.1 PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: scl:sce2902 GGDEF domain-containing protein; FHA domain containing protein 6372649 8329558 Amir_5356 Actinosynnema mirum DSM 43827 FHA domain containing protein YP_003103021.1 6372197 R 446462 CDS YP_003103022.1 256379362 8329559 complement(6372763..6373143) 1 NC_013093.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; KEGG: ank:AnaeK_2621 glycine cleavage system H protein; glycine cleavage system H protein 6373143 8329559 Amir_5357 Actinosynnema mirum DSM 43827 glycine cleavage system H protein YP_003103022.1 6372763 R 446462 CDS YP_003103023.1 256379363 8329560 complement(6373202..6373813) 1 NC_013093.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: tmz:Tmz1t_2031 CDP-diacylglycerol/glycerol-3- phosphate 3-phosphatidyltransferase; CDP-alcohol phosphatidyltransferase 6373813 8329560 Amir_5358 Actinosynnema mirum DSM 43827 CDP-alcohol phosphatidyltransferase YP_003103023.1 6373202 R 446462 CDS YP_003103024.1 256379364 8329561 complement(6374316..6374522) 1 NC_013093.1 hypothetical protein 6374522 8329561 Amir_5359 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103024.1 6374316 R 446462 CDS YP_003103025.1 256379365 8329562 6374938..6375354 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mag:amb0333 anti-anti-sigma regulatory factor; anti-sigma-factor antagonist 6375354 8329562 Amir_5360 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003103025.1 6374938 D 446462 CDS YP_003103026.1 256379366 8329563 complement(6375305..6376102) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: dvm:DvMF_0253 signal transduction histidine kinase; anti-sigma regulatory factor, serine/threonine protein kinase 6376102 8329563 Amir_5361 Actinosynnema mirum DSM 43827 anti-sigma regulatory factor, serine/threonine protein kinase YP_003103026.1 6375305 R 446462 CDS YP_003103027.1 256379367 8329564 6376261..6376698 1 NC_013093.1 KEGG: bsu:BSU04720 serine-protein kinase RsbW; anti-sigma regulatory factor, serine/threonine protein kinase 6376698 8329564 Amir_5362 Actinosynnema mirum DSM 43827 anti-sigma regulatory factor, serine/threonine protein kinase YP_003103027.1 6376261 D 446462 CDS YP_003103028.1 256379368 8329565 6376695..6377501 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 4 domain protein; KEGG: bha:BH0529 RNA polymerase sigma factor SigB; SigB/F/G subfamily RNA polymerase sigma-28 subunit 6377501 8329565 Amir_5363 Actinosynnema mirum DSM 43827 SigB/F/G subfamily RNA polymerase sigma-28 subunit YP_003103028.1 6376695 D 446462 CDS YP_003103029.1 256379369 8329566 6377686..6377985 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 6377985 8329566 Amir_5364 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003103029.1 6377686 D 446462 CDS YP_003103030.1 256379370 8329567 complement(6378158..6378817) 1 NC_013093.1 KEGG: mxa:MXAN_2497 hypothetical protein; hypothetical protein 6378817 8329567 Amir_5365 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103030.1 6378158 R 446462 CDS YP_003103031.1 256379371 8329568 6378900..6379853 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_0318 aldo/keto reductase; aldo/keto reductase 6379853 8329568 Amir_5366 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003103031.1 6378900 D 446462 CDS YP_003103032.1 256379372 8329569 complement(6379958..6380695) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6380695 8329569 Amir_5367 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103032.1 6379958 R 446462 CDS YP_003103033.1 256379373 8329570 complement(6381091..6382476) 1 NC_013093.1 KEGG: afw:Anae109_0266 response regulator receiver; hypothetical protein 6382476 8329570 Amir_5368 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103033.1 6381091 R 446462 CDS YP_003103034.1 256379374 8329571 complement(6382614..6383333) 1 NC_013093.1 KEGG: ank:AnaeK_0242 Fe-S oxidoreductase; transmembrane anti-sigma factor 6383333 8329571 Amir_5369 Actinosynnema mirum DSM 43827 transmembrane anti-sigma factor YP_003103034.1 6382614 R 446462 CDS YP_003103035.1 256379375 8329572 complement(6383330..6383875) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpb:RPB_0486 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit 6383875 8329572 Amir_5370 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103035.1 6383330 R 446462 CDS YP_003103036.1 256379376 8329573 complement(6384084..6384995) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6384995 8329573 Amir_5371 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103036.1 6384084 R 446462 CDS YP_003103037.1 256379377 8329574 6385160..6385462 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: rpt:Rpal_2803 transcriptional regulator, PadR- like family; PadR family transcriptional regulator 6385462 8329574 Amir_5372 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003103037.1 6385160 D 446462 CDS YP_003103038.1 256379378 8329575 complement(6385476..6386459) 1 NC_013093.1 PFAM: Radical SAM domain protein; KEGG: sat:SYN_02268 radical SAM superfamily protein; Radical SAM domain-containing protein 6386459 8329575 Amir_5373 Actinosynnema mirum DSM 43827 Radical SAM domain-containing protein YP_003103038.1 6385476 R 446462 CDS YP_003103039.1 256379379 8329576 6386659..6387315 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: oca:OCAR_4624 signal transduction histidine kinase containing PAS/PAC sensor domain; histidine kinase 6387315 8329576 Amir_5374 Actinosynnema mirum DSM 43827 histidine kinase YP_003103039.1 6386659 D 446462 CDS YP_003103040.1 256379380 8329577 6387312..6387968 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: bcr:BCAH187_A1601 DNA-binding response regulator; LuxR family transcriptional regulator 6387968 8329577 Amir_5375 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003103040.1 6387312 D 446462 CDS YP_003103041.1 256379381 8329578 6388249..6388890 1 NC_013093.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: bcy:Bcer98_1160 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 6388890 8329578 Amir_5376 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003103041.1 6388249 D 446462 CDS YP_003103042.1 256379382 8329579 complement(6388993..6390333) 1 NC_013093.1 KEGG: mucin-associated surface protein (MASP); hypothetical protein 6390333 8329579 Amir_5377 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103042.1 6388993 R 446462 CDS YP_003103043.1 256379383 8329580 complement(6390443..6393643) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: hypothetical protein; hypothetical protein 6393643 8329580 Amir_5378 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103043.1 6390443 R 446462 CDS YP_003103044.1 256379384 8329581 complement(6393676..6394797) 1 NC_013093.1 KEGG: mrd:Mrad2831_3727 translation initiation factor IF-2; FHA domain containing protein 6394797 8329581 Amir_5379 Actinosynnema mirum DSM 43827 FHA domain containing protein YP_003103044.1 6393676 R 446462 CDS YP_003103045.1 256379385 8329582 complement(6394794..6395333) 1 NC_013093.1 TIGRFAM: phage tail protein; KEGG: gsu:GSU0989 NHL repeat-containing protein; phage tail protein 6395333 8329582 Amir_5380 Actinosynnema mirum DSM 43827 phage tail protein YP_003103045.1 6394794 R 446462 CDS YP_003103046.1 256379386 8329583 complement(6395330..6397264) 1 NC_013093.1 KEGG: gsu:GSU0988 hypothetical protein; hypothetical protein 6397264 8329583 Amir_5381 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103046.1 6395330 R 446462 CDS YP_003103047.1 256379387 8329584 complement(6397264..6397671) 1 NC_013093.1 PFAM: GPW/gp25 family protein; KEGG: gsu:GSU0986 tail lysozyme; GPW/gp25 family protein 6397671 8329584 Amir_5382 Actinosynnema mirum DSM 43827 GPW/gp25 family protein YP_003103047.1 6397264 R 446462 CDS YP_003103048.1 256379388 8329585 complement(6397674..6397955) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: dar:Daro_3608 PaaR; hypothetical protein 6397955 8329585 Amir_5383 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103048.1 6397674 R 446462 CDS YP_003103049.1 256379389 8329586 complement(6398003..6399811) 1 NC_013093.1 TIGRFAM: Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: dsh:Dshi_2462 rhs element Vgr protein; Rhs element Vgr protein 6399811 8329586 Amir_5384 Actinosynnema mirum DSM 43827 Rhs element Vgr protein YP_003103049.1 6398003 R 446462 CDS YP_003103050.1 256379390 8329587 complement(6399804..6400559) 1 NC_013093.1 PFAM: peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: sde:Sde_1041 hypothetical protein; peptidoglycan-binding LysM 6400559 8329587 Amir_5385 Actinosynnema mirum DSM 43827 peptidoglycan-binding LysM YP_003103050.1 6399804 R 446462 CDS YP_003103051.1 256379391 8329588 complement(6400564..6400995) 1 NC_013093.1 TIGRFAM: conserved hypothetical protein; KEGG: noc:Noc_1873 phage tail region protein; hypothetical protein 6400995 8329588 Amir_5386 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103051.1 6400564 R 446462 CDS YP_003103052.1 256379392 8329589 complement(6401077..6403479) 1 NC_013093.1 KEGG: NACA, TEBP; nascent polypeptide-associated complex alpha subunit; hypothetical protein 6403479 8329589 Amir_5387 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103052.1 6401077 R 446462 CDS YP_003103053.1 256379393 8329590 complement(6403486..6403632) 1 NC_013093.1 KEGG: mlo:msr6553 hypothetical protein; hypothetical protein 6403632 8329590 Amir_5388 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103053.1 6403486 R 446462 CDS YP_003103054.1 256379394 8329591 complement(6403629..6404042) 1 NC_013093.1 KEGG: gsu:GSU0977 hypothetical protein; hypothetical protein 6404042 8329591 Amir_5389 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103054.1 6403629 R 446462 CDS YP_003103055.1 256379395 8329592 complement(6404042..6404485) 1 NC_013093.1 TIGRFAM: conserved hypothetical protein; KEGG: gsu:GSU0976 hypothetical protein; hypothetical protein 6404485 8329592 Amir_5390 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103055.1 6404042 R 446462 CDS YP_003103056.1 256379396 8329593 complement(6404500..6406044) 1 NC_013093.1 PFAM: tail sheath protein; KEGG: mlo:mlr6548 hypothetical protein; tail sheath protein 6406044 8329593 Amir_5391 Actinosynnema mirum DSM 43827 tail sheath protein YP_003103056.1 6404500 R 446462 CDS YP_003103057.1 256379397 8329594 complement(6406289..6407020) 1 NC_013093.1 KEGG: nha:Nham_0826 hypothetical protein; hypothetical protein 6407020 8329594 Amir_5392 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103057.1 6406289 R 446462 CDS YP_003103058.1 256379398 8329595 complement(6407067..6409115) 1 NC_013093.1 PFAM: ATPase AAA; SMART: ATPase AAA; KEGG: gsu:GSU0972 AAA family ATPase; ATPase AAA 6409115 8329595 Amir_5393 Actinosynnema mirum DSM 43827 ATPase AAA YP_003103058.1 6407067 R 446462 CDS YP_003103059.1 256379399 8329596 complement(6409112..6409699) 1 NC_013093.1 KEGG: noc:Noc_1875 hypothetical protein; hypothetical protein 6409699 8329596 Amir_5394 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103059.1 6409112 R 446462 CDS YP_003103060.1 256379400 8329597 6410006..6410854 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 6410854 8329597 Amir_5395 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103060.1 6410006 D 446462 CDS YP_003103061.1 256379401 8329598 6410851..6411051 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 6411051 8329598 Amir_5396 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103061.1 6410851 D 446462 CDS YP_003103062.1 256379402 8329599 complement(6411057..6414092) 1 NC_013093.1 KEGG: scl:sce3623 hypothetical protein; hypothetical protein 6414092 8329599 Amir_5397 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103062.1 6411057 R 446462 CDS YP_003103063.1 256379403 8329600 6414473..6414841 1 NC_013093.1 hypothetical protein 6414841 8329600 Amir_5398 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103063.1 6414473 D 446462 CDS YP_003103064.1 256379404 8329601 6414838..6415569 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 3 domain protein; KEGG: bha:BH0529 RNA polymerase sigma factor SigB; SigB/F/G subfamily RNA polymerase sigma-28 subunit 6415569 8329601 Amir_5399 Actinosynnema mirum DSM 43827 SigB/F/G subfamily RNA polymerase sigma-28 subunit YP_003103064.1 6414838 D 446462 CDS YP_003103065.1 256379405 8329602 6415585..6416061 1 NC_013093.1 KEGG: mpt:Mpe_A0228 hypothetical protein; hypothetical protein 6416061 8329602 Amir_5400 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103065.1 6415585 D 446462 CDS YP_003103066.1 256379406 8329603 6416153..6417079 1 NC_013093.1 KEGG: mca:MCA0157 hypothetical protein; hypothetical protein 6417079 8329603 Amir_5401 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103066.1 6416153 D 446462 CDS YP_003103067.1 256379407 8329604 6417303..6418394 1 NC_013093.1 PFAM: glutamate--cysteine ligase GCS2; KEGG: sus:Acid_3926 carboxylate-amine ligase; glutamate--cysteine ligase GCS2 6418394 8329604 Amir_5402 Actinosynnema mirum DSM 43827 glutamate--cysteine ligase GCS2 YP_003103067.1 6417303 D 446462 CDS YP_003103068.1 256379408 8329605 6418455..6418811 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist; anti-sigma-factor antagonist 6418811 8329605 Amir_5403 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003103068.1 6418455 D 446462 CDS YP_003103069.1 256379409 8329606 complement(6419020..6419364) 1 NC_013093.1 hypothetical protein 6419364 8329606 Amir_5404 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103069.1 6419020 R 446462 CDS YP_003103070.1 256379410 8329607 complement(6419495..6419938) 1 NC_013093.1 KEGG: rru:Rru_A3720 polysaccharide biosynthesis protein; hypothetical protein 6419938 8329607 Amir_5405 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103070.1 6419495 R 446462 CDS YP_003103071.1 256379411 8329608 complement(6419935..6420552) 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; KEGG: bca:BCE_3203 ThiJ/PfpI family protein; ThiJ/PfpI domain-containing protein 6420552 8329608 Amir_5406 Actinosynnema mirum DSM 43827 ThiJ/PfpI domain-containing protein YP_003103071.1 6419935 R 446462 CDS YP_003103072.1 256379412 8329609 6420660..6421601 1 NC_013093.1 PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6302 AraC family transcriptional regulator; AraC family transcriptional regulator 6421601 8329609 Amir_5407 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003103072.1 6420660 D 446462 CDS YP_003103073.1 256379413 8329610 6421844..6423712 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_3338 serine/threonine protein kinase; serine/threonine protein kinase 6423712 8329610 Amir_5408 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003103073.1 6421844 D 446462 CDS YP_003103074.1 256379414 8329611 complement(6423709..6424185) 1 NC_013093.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: smt:Smal_3461 CMP/dCMP deaminase zinc-binding; zinc-binding CMP/dCMP deaminase 6424185 8329611 Amir_5409 Actinosynnema mirum DSM 43827 zinc-binding CMP/dCMP deaminase YP_003103074.1 6423709 R 446462 CDS YP_003103075.1 256379415 8329612 complement(6424241..6424756) 1 NC_013093.1 KEGG: ade:Adeh_3063 VCBS; hypothetical protein 6424756 8329612 Amir_5410 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103075.1 6424241 R 446462 CDS YP_003103076.1 256379416 8329613 complement(6424892..6427513) 1 NC_013093.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: sus:Acid_3454 tetratricopeptide TPR_4; hypothetical protein 6427513 8329613 Amir_5411 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103076.1 6424892 R 446462 CDS YP_003103077.1 256379417 8329614 6427591..6428805 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: ade:Adeh_0234 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 6428805 8329614 Amir_5412 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003103077.1 6427591 D 446462 CDS YP_003103078.1 256379418 8329615 6428968..6429627 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: sus:Acid_3455 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 6429627 8329615 Amir_5413 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103078.1 6428968 D 446462 CDS YP_003103079.1 256379419 8329616 6429611..6430048 1 NC_013093.1 hypothetical protein 6430048 8329616 Amir_5414 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103079.1 6429611 D 446462 CDS YP_003103080.1 256379420 8329617 6430567..6432522 1 NC_013093.1 KEGG: azo:azo0950 GGEF/EAL/PAS/PAC-domain- containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat- containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 6432522 8329617 Amir_5415 Actinosynnema mirum DSM 43827 PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase YP_003103080.1 6430567 D 446462 CDS YP_003103081.1 256379421 8329618 complement(6432628..6433215) 1 NC_013093.1 PFAM: protein of unknown function ATP binding; Miro domain protein; KEGG: dac:Daci_0776 protein of unknown function ATP binding; hypothetical protein 6433215 8329618 Amir_5416 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103081.1 6432628 R 446462 CDS YP_003103082.1 256379422 8329619 complement(6433254..6433676) 1 NC_013093.1 PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_2813 roadblock/LC7 family protein; Roadblock/LC7 family protein 6433676 8329619 Amir_5417 Actinosynnema mirum DSM 43827 Roadblock/LC7 family protein YP_003103082.1 6433254 R 446462 CDS YP_003103083.1 256379423 8329620 complement(6433673..6436855) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: dvm:DvMF_1114 methyl-accepting chemotaxis sensory transducer; sensor with HAMP domain 6436855 8329620 Amir_5418 Actinosynnema mirum DSM 43827 sensor with HAMP domain YP_003103083.1 6433673 R 446462 CDS YP_003103084.1 256379424 8329621 complement(6437119..6438156) 1 NC_013093.1 PFAM: NMT1/THI5 like domain protein; KEGG: bbt:BBta_5981 ABC transporter substrate- binding protein; NMT1/THI5 like domain-containing protein 6438156 8329621 Amir_5419 Actinosynnema mirum DSM 43827 NMT1/THI5 like domain-containing protein YP_003103084.1 6437119 R 446462 CDS YP_003103085.1 256379425 8329622 6438347..6439549 1 NC_013093.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 6439549 8329622 Amir_5420 Actinosynnema mirum DSM 43827 4-hydroxybenzoate 3-monooxygenase YP_003103085.1 6438347 D 446462 CDS YP_003103086.1 256379426 8329623 complement(6440358..6441242) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ABC transporter; ABC transporter 6441242 8329623 Amir_5421 Actinosynnema mirum DSM 43827 ABC transporter YP_003103086.1 6440358 R 446462 CDS YP_003103087.1 256379427 8329624 complement(6441244..6442053) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ABC transporter, permease protein; ABC transporter inner membrane protein 6442053 8329624 Amir_5422 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003103087.1 6441244 R 446462 CDS YP_003103088.1 256379428 8329625 complement(6442050..6442946) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_1369 ABC transporter membrane protein; ABC transporter inner membrane protein 6442946 8329625 Amir_5423 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003103088.1 6442050 R 446462 CDS YP_003103089.1 256379429 8329626 complement(6442998..6443234) 1 NC_013093.1 hypothetical protein 6443234 8329626 Amir_5424 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103089.1 6442998 R 446462 CDS YP_003103090.1 256379430 8329627 complement(6443568..6444308) 1 NC_013093.1 PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: sat:SYN_02856 RNA pseudouridylate synthase S4 domain-containing protein; pseudouridine synthase 6444308 8329627 Amir_5425 Actinosynnema mirum DSM 43827 pseudouridine synthase YP_003103090.1 6443568 R 446462 CDS YP_003103091.1 256379431 8329628 complement(6444301..6444882) 1 NC_013093.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: sus:Acid_6490 condensin subunit ScpB; chromosome segregation and condensation protein ScpB 6444882 8329628 Amir_5426 Actinosynnema mirum DSM 43827 chromosome segregation and condensation protein ScpB YP_003103091.1 6444301 R 446462 CDS YP_003103092.1 256379432 8329629 complement(6444879..6445814) 1 NC_013093.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: mxa:MXAN_3841 segregation and condensation protein A; chromosome segregation and condensation protein ScpA 6445814 8329629 Amir_5427 Actinosynnema mirum DSM 43827 chromosome segregation and condensation protein ScpA YP_003103092.1 6444879 R 446462 CDS YP_003103093.1 256379433 8329630 complement(6445811..6446380) 1 NC_013093.1 KEGG: similar to Williams syndrome transcription factor; hypothetical protein 6446380 8329630 Amir_5428 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103093.1 6445811 R 446462 CDS YP_003103094.1 256379434 8329631 complement(6446377..6447345) 1 NC_013093.1 PFAM: cobyrinic acid ac-diamide synthase; KEGG: bcb:BCB4264_A5607 sporulation initiation inhibitor protein Soj; cobyrinic acid ac-diamide synthase 6447345 8329631 Amir_5429 Actinosynnema mirum DSM 43827 cobyrinic acid ac-diamide synthase YP_003103094.1 6446377 R 446462 CDS YP_003103095.1 256379435 8329632 complement(6447438..6447770) 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bca:BCE_2079 ArsR family transcriptional regulator; ArsR family transcriptional regulator 6447770 8329632 Amir_5430 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003103095.1 6447438 R 446462 CDS YP_003103096.1 256379436 8329633 complement(6447935..6448834) 1 NC_013093.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: acp:A2cp1_2258 tyrosine recombinase XerD; tyrosine recombinase XerD 6448834 8329633 Amir_5431 Actinosynnema mirum DSM 43827 tyrosine recombinase XerD YP_003103096.1 6447935 R 446462 CDS YP_003103097.1 256379437 8329634 6448917..6449501 1 NC_013093.1 PFAM: protein of unknown function DUF1707; TM2 domain containing protein?; KEGG: scl:sce7607 TM2 domain-containing protein; hypothetical protein 6449501 8329634 Amir_5432 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103097.1 6448917 D 446462 CDS YP_003103098.1 256379438 8329635 complement(6449649..6450074) 1 NC_013093.1 KEGG: pca:Pcar_0371 hypothetical protein; hypothetical protein 6450074 8329635 Amir_5433 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103098.1 6449649 R 446462 CDS YP_003103099.1 256379439 8329636 complement(6450314..6450955) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: dol:Dole_1905 NUDIX hydrolase; NUDIX hydrolase 6450955 8329636 Amir_5434 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003103099.1 6450314 R 446462 CDS YP_003103100.1 256379440 8329637 complement(6450997..6452766) 1 NC_013093.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 6452766 pyrG 8329637 pyrG Actinosynnema mirum DSM 43827 CTP synthetase YP_003103100.1 6450997 R 446462 CDS YP_003103101.1 256379441 8329638 complement(6452963..6453889) 1 NC_013093.1 KEGG: acp:A2cp1_3214 PE-PGRS family protein; hypothetical protein 6453889 8329638 Amir_5436 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103101.1 6452963 R 446462 CDS YP_003103102.1 256379442 8329639 complement(6453895..6455079) 1 NC_013093.1 KEGG: bha:BH2771 hypothetical protein; membrane-anchored protein 6455079 8329639 Amir_5437 Actinosynnema mirum DSM 43827 membrane-anchored protein YP_003103102.1 6453895 R 446462 CDS YP_003103103.1 256379443 8329640 complement(6455221..6456480) 1 NC_013093.1 hypothetical protein 6456480 8329640 Amir_5438 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103103.1 6455221 R 446462 CDS YP_003103104.1 256379444 8329641 complement(6456790..6458568) 1 NC_013093.1 TIGRFAM: DNA repair protein RecN; PFAM: hypothetical protein; KEGG: acp:A2cp1_0769 DNA repair protein RecN; DNA repair protein RecN 6458568 8329641 Amir_5439 Actinosynnema mirum DSM 43827 DNA repair protein RecN YP_003103104.1 6456790 R 446462 CDS YP_003103105.1 256379445 8329642 complement(6458607..6459509) 1 NC_013093.1 PFAM: ATP-NAD/AcoX kinase; KEGG: ATP-NAD/AcoX kinase; K00858 NAD+ kinase; NAD(+) kinase 6459509 8329642 Amir_5440 Actinosynnema mirum DSM 43827 NAD(+) kinase YP_003103105.1 6458607 R 446462 CDS YP_003103106.1 256379446 8329643 complement(6459506..6460312) 1 NC_013093.1 KEGG: acp:A2cp1_1226 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; hemolysin A 6460312 8329643 Amir_5441 Actinosynnema mirum DSM 43827 hemolysin A YP_003103106.1 6459506 R 446462 CDS YP_003103107.1 256379447 8329644 complement(6460319..6460492) 1 NC_013093.1 hypothetical protein 6460492 8329644 Amir_5442 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103107.1 6460319 R 446462 CDS YP_003103108.1 256379448 8329645 complement(6460489..6461283) 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bat:BAS4827 phosphatase; HAD superfamily hydrolase 6461283 8329645 Amir_5443 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003103108.1 6460489 R 446462 CDS YP_003103109.1 256379449 8329646 complement(6461835..6464591) 1 NC_013093.1 KEGG: dvu:DVU0907 hypothetical protein; hypothetical protein 6464591 8329646 Amir_5444 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103109.1 6461835 R 446462 CDS YP_003103110.1 256379450 8329651 complement(6470460..6471743) 1 NC_013093.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 6471743 8329651 Amir_5445 Actinosynnema mirum DSM 43827 tyrosyl-tRNA synthetase YP_003103110.1 6470460 R 446462 CDS YP_003103111.1 256379451 8329652 complement(6471778..6473502) 1 NC_013093.1 hypothetical protein 6473502 8329652 Amir_5446 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103111.1 6471778 R 446462 CDS YP_003103112.1 256379452 8329653 6473611..6474132 1 NC_013093.1 PFAM: calcium-binding EF-hand-containing protein; SMART: calcium-binding EF-hand-containing protein; KEGG: Scp2; Sarcoplasmic calcium-binding protein 2; signal transduction protein with EFhand domain 6474132 8329653 Amir_5447 Actinosynnema mirum DSM 43827 signal transduction protein with EFhand domain YP_003103112.1 6473611 D 446462 CDS YP_003103113.1 256379453 8329654 complement(6474160..6474789) 1 NC_013093.1 TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); KEGG: bmu:Bmul_0540 3-methyladenine DNA glycosylase; DNA-3-methyladenine glycosylase 6474789 8329654 Amir_5448 Actinosynnema mirum DSM 43827 DNA-3-methyladenine glycosylase YP_003103113.1 6474160 R 446462 CDS YP_003103114.1 256379454 8329655 complement(6474773..6476164) 1 NC_013093.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 6476164 8329655 Amir_5449 Actinosynnema mirum DSM 43827 argininosuccinate lyase YP_003103114.1 6474773 R 446462 CDS YP_003103115.1 256379455 8329656 complement(6476259..6477206) 1 NC_013093.1 PFAM: argininosuccinate synthase; KEGG: bha:BH3187 argininosuccinate synthase; Argininosuccinate synthase 6477206 8329656 Amir_5450 Actinosynnema mirum DSM 43827 Argininosuccinate synthase YP_003103115.1 6476259 R 446462 CDS YP_003103116.1 256379456 8329657 complement(6477709..6478203) 1 NC_013093.1 TIGRFAM: arginine repressor; PFAM: arginine repressor; KEGG: afw:Anae109_0631 arginine repressor, ArgR; arginine repressor, ArgR 6478203 8329657 Amir_5451 Actinosynnema mirum DSM 43827 arginine repressor, ArgR YP_003103116.1 6477709 R 446462 CDS YP_003103117.1 256379457 8329658 complement(6478200..6479132) 1 NC_013093.1 TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: afr:AFE_0405 ornithine carbamoyltransferase; ornithine carbamoyltransferase 6479132 8329658 Amir_5452 Actinosynnema mirum DSM 43827 ornithine carbamoyltransferase YP_003103117.1 6478200 R 446462 CDS YP_003103118.1 256379458 8329659 complement(6479138..6480301) 1 NC_013093.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 6480301 argD 8329659 argD Actinosynnema mirum DSM 43827 acetylornithine aminotransferase YP_003103118.1 6479138 R 446462 CDS YP_003103119.1 256379459 8329660 complement(6480298..6481200) 1 NC_013093.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 6481200 8329660 Amir_5454 Actinosynnema mirum DSM 43827 acetylglutamate kinase YP_003103119.1 6480298 R 446462 CDS YP_003103120.1 256379460 8329661 complement(6481197..6482369) 1 NC_013093.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 6482369 argJ 8329661 argJ Actinosynnema mirum DSM 43827 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_003103120.1 6481197 R 446462 CDS YP_003103121.1 256379461 8329662 complement(6482366..6483388) 1 NC_013093.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 6483388 argC 8329662 argC Actinosynnema mirum DSM 43827 N-acetyl-gamma-glutamyl-phosphate reductase YP_003103121.1 6482366 R 446462 CDS YP_003103122.1 256379462 8329663 complement(6483447..6484394) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: scl:sce1535 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 6484394 8329663 Amir_5457 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003103122.1 6483447 R 446462 CDS YP_003103123.1 256379463 8329665 6484733..6485830 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: sbc:SbBS512_A0291 transposase (IS4 family); transposase IS4 family protein 6485830 8329665 Amir_5459 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003103123.1 6484733 D 446462 CDS YP_003103124.1 256379464 8329666 complement(6486006..6486245) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: mmr:Mmar10_0512 XRE family transcriptional regulator; XRE family transcriptional regulator 6486245 8329666 Amir_5460 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103124.1 6486006 R 446462 CDS YP_003103125.1 256379465 8329667 complement(6486239..6486682) 1 NC_013093.1 KEGG: cak:Caul_3518 hypothetical protein; hypothetical protein 6486682 8329667 Amir_5461 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103125.1 6486239 R 446462 CDS YP_003103126.1 256379466 8329668 complement(6486787..6488202) 1 NC_013093.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 6488202 8329668 Amir_5462 Actinosynnema mirum DSM 43827 soluble pyridine nucleotide transhydrogenase YP_003103126.1 6486787 R 446462 CDS YP_003103127.1 256379467 8329669 complement(6488290..6488787) 1 NC_013093.1 hypothetical protein 6488787 8329669 Amir_5463 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103127.1 6488290 R 446462 CDS YP_003103128.1 256379468 8329670 complement(6489099..6491576) 1 NC_013093.1 KEGG: pca:Pcar_1423 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; phenylalanyl-tRNA synthetase subunit beta 6491576 8329670 Amir_5464 Actinosynnema mirum DSM 43827 phenylalanyl-tRNA synthetase subunit beta YP_003103128.1 6489099 R 446462 CDS YP_003103129.1 256379469 8329671 complement(6491580..6492647) 1 NC_013093.1 TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: cja:CJA_2526 phenylalanyl-tRNA synthetase, alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 6492647 8329671 Amir_5465 Actinosynnema mirum DSM 43827 phenylalanyl-tRNA synthetase subunit alpha YP_003103129.1 6491580 R 446462 CDS YP_003103130.1 256379470 8329672 6492830..6494587 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: mxa:MXAN_1393 ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; HSP90 family protein 6494587 8329672 Amir_5466 Actinosynnema mirum DSM 43827 HSP90 family protein YP_003103130.1 6492830 D 446462 CDS YP_003103131.1 256379471 8329673 6494601..6497432 1 NC_013093.1 PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: mxa:MXAN_1392 hypothetical protein; hypothetical protein 6497432 8329673 Amir_5467 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103131.1 6494601 D 446462 CDS YP_003103132.1 256379472 8329674 6497572..6498243 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sus:Acid_5477 two component transcriptional regulator; winged helix family two component transcriptional regulator 6498243 8329674 Amir_5468 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003103132.1 6497572 D 446462 CDS YP_003103133.1 256379473 8329675 6498240..6499610 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: psa:PST_4043 sensor histidine kinase TctE; histidine kinase 6499610 8329675 Amir_5469 Actinosynnema mirum DSM 43827 histidine kinase YP_003103133.1 6498240 D 446462 CDS YP_003103134.1 256379474 8329676 complement(6499607..6500455) 1 NC_013093.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: ret:RHE_CH00393 rRNA methylase; tRNA/rRNA methyltransferase SpoU 6500455 8329676 Amir_5470 Actinosynnema mirum DSM 43827 tRNA/rRNA methyltransferase SpoU YP_003103134.1 6499607 R 446462 CDS YP_003103135.1 256379475 8329677 complement(6500455..6500844) 1 NC_013093.1 TIGRFAM: ribosomal protein L20; PFAM: ribosomal protein L20; KEGG: pfo:Pfl01_1934 50S ribosomal protein L20; 50S ribosomal protein L20 6500844 8329677 Amir_5471 Actinosynnema mirum DSM 43827 50S ribosomal protein L20 YP_003103135.1 6500455 R 446462 CDS YP_003103136.1 256379476 8329678 complement(6500906..6501100) 1 NC_013093.1 TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: aba:Acid345_0714 LSU ribosomal protein L35P; 50S ribosomal protein L35 6501100 rpmI 8329678 rpmI Actinosynnema mirum DSM 43827 50S ribosomal protein L35 YP_003103136.1 6500906 R 446462 CDS YP_003103137.1 256379477 8329679 complement(6501185..6501799) 1 NC_013093.1 TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3; KEGG: ftm:FTM_1017 translation initiation factor IF- 3; translation initiation factor IF-3 6501799 8329679 Amir_5473 Actinosynnema mirum DSM 43827 translation initiation factor IF-3 YP_003103137.1 6501185 R 446462 CDS YP_003103138.1 256379478 8329680 6502081..6502422 1 NC_013093.1 hypothetical protein 6502422 8329680 Amir_5474 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103138.1 6502081 D 446462 CDS YP_003103139.1 256379479 8329681 complement(6502580..6503233) 1 NC_013093.1 hypothetical protein 6503233 8329681 Amir_5475 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103139.1 6502580 R 446462 CDS YP_003103140.1 256379480 8329682 6503436..6505721 1 NC_013093.1 PFAM: helix-turn-helix domain protein; NB-ARC domain protein; SMART: helix-turn-helix domain protein; ATPase AAA; KEGG: scl:sce5225 protein kinase; XRE family transcriptional regulator 6505721 8329682 Amir_5476 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103140.1 6503436 D 446462 CDS YP_003103141.1 256379481 8329683 complement(6505946..6506332) 1 NC_013093.1 TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: mmw:Mmwyl1_4387 endoribonuclease L- PSP; endoribonuclease L-PSP 6506332 8329683 Amir_5477 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003103141.1 6505946 R 446462 CDS YP_003103142.1 256379482 8329684 complement(6506349..6507098) 1 NC_013093.1 PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: bha:BH2137 IclR family transcriptional regulator; IclR family transcriptional regulator 6507098 8329684 Amir_5478 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003103142.1 6506349 R 446462 CDS YP_003103143.1 256379483 8329685 complement(6507095..6508060) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: bha:BH3724 2-keto-3-deoxygluconate kinase; PfkB domain-containing protein 6508060 8329685 Amir_5479 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003103143.1 6507095 R 446462 CDS YP_003103144.1 256379484 8329686 6508172..6509461 1 NC_013093.1 PFAM: alanine racemase domain protein; KEGG: lch:Lcho_0086 D-serine deaminase; alanine racemase domain-containing protein 6509461 8329686 Amir_5480 Actinosynnema mirum DSM 43827 alanine racemase domain-containing protein YP_003103144.1 6508172 D 446462 CDS YP_003103145.1 256379485 8329687 6509522..6511111 1 NC_013093.1 PFAM: Amidohydrolase 3; D-aminoacylase domain protein; amidohydrolase; KEGG: hypothetical protein; N-acyl-D-amino-acid deacylase 6511111 8329687 Amir_5481 Actinosynnema mirum DSM 43827 N-acyl-D-amino-acid deacylase YP_003103145.1 6509522 D 446462 CDS YP_003103146.1 256379486 8329688 6511108..6512502 1 NC_013093.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: oan:Oant_4271 gluconate transporter; gluconate transporter 6512502 8329688 Amir_5482 Actinosynnema mirum DSM 43827 gluconate transporter YP_003103146.1 6511108 D 446462 CDS YP_003103147.1 256379487 8329689 complement(6512671..6515535) 1 NC_013093.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 6515535 uvrA 8329689 uvrA Actinosynnema mirum DSM 43827 excinuclease ABC subunit A YP_003103147.1 6512671 R 446462 CDS YP_003103148.1 256379488 8329690 6515834..6516553 1 NC_013093.1 in Corynebacterium glutamicum this enzyme catalyzes the conversion of maleylpyruvate into fumarylpyruvate in a glutathione-independent gentisate pathway; dependent on mycothiol; mycothiol-dependent maleylpyruvate isomerase 6516553 8329690 Amir_5484 Actinosynnema mirum DSM 43827 mycothiol-dependent maleylpyruvate isomerase YP_003103148.1 6515834 D 446462 CDS YP_003103149.1 256379489 8329691 complement(6516406..6517590) 1 NC_013093.1 PFAM: acyltransferase 3; KEGG: maq:Maqu_3475 acyltransferase 3; acyltransferase 3 6517590 8329691 Amir_5485 Actinosynnema mirum DSM 43827 acyltransferase 3 YP_003103149.1 6516406 R 446462 CDS YP_003103150.1 256379490 8329692 6517722..6518399 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: gme:Gmet_2674 beta-lactamase-like; beta-lactamase domain-containing protein 6518399 8329692 Amir_5486 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003103150.1 6517722 D 446462 CDS YP_003103151.1 256379491 8329693 complement(6519162..6520460) 1 NC_013093.1 hypothetical protein 6520460 8329693 Amir_5487 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103151.1 6519162 R 446462 CDS YP_003103152.1 256379492 8329694 6521183..6521437 1 NC_013093.1 hypothetical protein 6521437 8329694 Amir_5488 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103152.1 6521183 D 446462 CDS YP_003103153.1 256379493 8329695 complement(6522106..6522792) 1 NC_013093.1 KEGG: hypothetical protein LOC762973; hypothetical protein 6522792 8329695 Amir_5489 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103153.1 6522106 R 446462 CDS YP_003103154.1 256379494 8329696 complement(6522890..6524023) 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein; GntR family transcriptional regulator 6524023 8329696 Amir_5490 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003103154.1 6522890 R 446462 CDS YP_003103155.1 256379495 8329697 6524354..6524653 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bpt:Bpet3500 ArsR family transcriptional regulator; ArsR family transcriptional regulator 6524653 8329697 Amir_5491 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003103155.1 6524354 D 446462 CDS YP_003103156.1 256379496 8329698 6524650..6525540 1 NC_013093.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: ank:AnaeK_2658 activator of HSP90 ATPase 1 family protein; Activator of Hsp90 ATPase 1 family protein 6525540 8329698 Amir_5492 Actinosynnema mirum DSM 43827 Activator of Hsp90 ATPase 1 family protein YP_003103156.1 6524650 D 446462 CDS YP_003103157.1 256379497 8329699 complement(6525678..6526652) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6526652 8329699 Amir_5493 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103157.1 6525678 R 446462 CDS YP_003103158.1 256379498 8329700 6526872..6527306 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: cti:RALTA_B0884 transcriptional regulator, AraC family, isolated domain; AraC family transcriptional regulator 6527306 8329700 Amir_5494 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003103158.1 6526872 D 446462 CDS YP_003103159.1 256379499 8329701 6527303..6527713 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cti:RALTA_B0885 lyase; glyoxalase/bleomycin resistance protein/dioxygenase 6527713 8329701 Amir_5495 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003103159.1 6527303 D 446462 CDS YP_003103160.1 256379500 8329702 6527847..6528404 1 NC_013093.1 PFAM: protein of unknown function DUF309; KEGG: dvm:DvMF_2231 protein of unknown function DUF309; hypothetical protein 6528404 8329702 Amir_5496 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103160.1 6527847 D 446462 CDS YP_003103161.1 256379501 8329703 6528401..6529045 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pla:Plav_0958 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 6529045 8329703 Amir_5497 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103161.1 6528401 D 446462 CDS YP_003103162.1 256379502 8329704 6529077..6529259 1 NC_013093.1 hypothetical protein 6529259 8329704 Amir_5498 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103162.1 6529077 D 446462 CDS YP_003103163.1 256379503 8329705 complement(6529973..6530125) 1 NC_013093.1 hypothetical protein 6530125 8329705 Amir_5499 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103163.1 6529973 R 446462 CDS YP_003103164.1 256379504 8329706 complement(6530198..6531400) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: acp:A2cp1_3940 hypothetical protein; helix-turn-helix domain-containing protein 6531400 8329706 Amir_5500 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003103164.1 6530198 R 446462 CDS YP_003103165.1 256379505 8329707 6532862..6533632 1 NC_013093.1 PFAM: protein of unknown function DUF540; KEGG: maq:Maqu_3616 hypothetical protein; hypothetical protein 6533632 8329707 Amir_5501 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103165.1 6532862 D 446462 CDS YP_003103166.1 256379506 8329708 complement(6533778..6534605) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: AGAP008296-PA; peptidase S1 and S6 chymotrypsin/Hap 6534605 8329708 Amir_5502 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003103166.1 6533778 R 446462 CDS YP_003103167.1 256379507 8329709 6534783..6535157 1 NC_013093.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: tbd:Tbd_2152 peptidyl-prolyl cis-trans isomerase; FKBP-type peptidylprolyl isomerase 6535157 8329709 Amir_5503 Actinosynnema mirum DSM 43827 FKBP-type peptidylprolyl isomerase YP_003103167.1 6534783 D 446462 CDS YP_003103168.1 256379508 8329710 6535463..6536029 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6536029 8329710 Amir_5504 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103168.1 6535463 D 446462 CDS YP_003103169.1 256379509 8329711 6536137..6537210 1 NC_013093.1 KEGG: predicted gene, EG114600; hypothetical protein 6537210 8329711 Amir_5505 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103169.1 6536137 D 446462 CDS YP_003103170.1 256379510 8329712 complement(6537318..6538505) 1 NC_013093.1 KEGG: hne:HNE_2077 hypothetical protein; hypothetical protein 6538505 8329712 Amir_5506 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103170.1 6537318 R 446462 CDS YP_003103171.1 256379511 8329713 6538702..6539286 1 NC_013093.1 KEGG: pla:Plav_3469 hypothetical protein; hypothetical protein 6539286 8329713 Amir_5507 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103171.1 6538702 D 446462 CDS YP_003103172.1 256379512 8329714 6540197..6540853 1 NC_013093.1 PFAM: hypothetical protein; KEGG: rsh:Rsph17029_3025 hypothetical protein; hypothetical protein 6540853 8329714 Amir_5508 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103172.1 6540197 D 446462 CDS YP_003103173.1 256379513 8329715 complement(6541042..6541629) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce8211 adenylattransferase; GCN5-like N-acetyltransferase 6541629 8329715 Amir_5509 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103173.1 6541042 R 446462 CDS YP_003103174.1 256379514 8329716 complement(6541663..6542280) 1 NC_013093.1 hypothetical protein 6542280 8329716 Amir_5510 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103174.1 6541663 R 446462 CDS YP_003103175.1 256379515 8329717 complement(6542277..6542960) 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: dal:Dalk_5197 transcriptional regulator, Crp/Fnr family; Crp/Fnr family transcriptional regulator 6542960 8329717 Amir_5511 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003103175.1 6542277 R 446462 CDS YP_003103176.1 256379516 8329718 complement(6543220..6545124) 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; dienelactone hydrolase; hypothetical protein; acetyl xylan esterase; KEGG: bsu:BSU32230 hypothetical protein; peptidase S9 prolyl oligopeptidase active site domain-containing protein 6545124 8329718 Amir_5512 Actinosynnema mirum DSM 43827 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_003103176.1 6543220 R 446462 CDS YP_003103177.1 256379517 8329719 complement(6545189..6546181) 1 NC_013093.1 PFAM: integral membrane protein TerC; KEGG: csa:Csal_1104 integral membrane protein TerC; integral membrane protein TerC 6546181 8329719 Amir_5513 Actinosynnema mirum DSM 43827 integral membrane protein TerC YP_003103177.1 6545189 R 446462 CDS YP_003103178.1 256379518 8329720 6546560..6549466 1 NC_013093.1 PFAM: ABC transporter; peptidase S15; alpha/beta hydrolase fold; SMART: ATPase AAA; KEGG: bcz:BCZK3372 bacitracin ABC transporter, ATP- binding protein; ABC transporter 6549466 8329720 Amir_5514 Actinosynnema mirum DSM 43827 ABC transporter YP_003103178.1 6546560 D 446462 CDS YP_003103179.1 256379519 8329721 6549463..6550446 1 NC_013093.1 KEGG: rso:RSp1372 NosY transmembrane protein; hypothetical protein 6550446 8329721 Amir_5515 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103179.1 6549463 D 446462 CDS YP_003103180.1 256379520 8329722 complement(6550512..6552683) 1 NC_013093.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 6552683 8329722 Amir_5516 Actinosynnema mirum DSM 43827 excinuclease ABC subunit B YP_003103180.1 6550512 R 446462 CDS YP_003103181.1 256379521 8329723 complement(6552768..6554081) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6554081 8329723 Amir_5517 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103181.1 6552768 R 446462 CDS YP_003103182.1 256379522 8329724 6554188..6554733 1 NC_013093.1 hypothetical protein 6554733 8329724 Amir_5518 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103182.1 6554188 D 446462 CDS YP_003103183.1 256379523 8329725 6554881..6555402 1 NC_013093.1 hypothetical protein 6555402 8329725 Amir_5519 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103183.1 6554881 D 446462 CDS YP_003103184.1 256379524 8329726 complement(6555372..6556556) 1 NC_013093.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain; dephospho-CoA kinase/protein folding accessory domain-containing protein 6556556 coaE 8329726 coaE Actinosynnema mirum DSM 43827 dephospho-CoA kinase/protein folding accessory domain-containing protein YP_003103184.1 6555372 R 446462 CDS YP_003103185.1 256379525 8329727 complement(6556597..6557217) 1 NC_013093.1 hypothetical protein 6557217 8329727 Amir_5521 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103185.1 6556597 R 446462 CDS YP_003103186.1 256379526 8329728 complement(6557513..6559000) 1 NC_013093.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 6559000 rpsA 8329728 rpsA Actinosynnema mirum DSM 43827 30S ribosomal protein S1 YP_003103186.1 6557513 R 446462 CDS YP_003103187.1 256379527 8329729 6559192..6560022 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: ank:AnaeK_1219 methyltransferase type 11; type 11 methyltransferase 6560022 8329729 Amir_5523 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003103187.1 6559192 D 446462 CDS YP_003103188.1 256379528 8329730 6560033..6560959 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sil:SPO0965 acetyltransferase; GCN5-like N-acetyltransferase 6560959 8329730 Amir_5524 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103188.1 6560033 D 446462 CDS YP_003103189.1 256379529 8329731 6561709..6562344 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6562344 8329731 Amir_5525 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103189.1 6561709 D 446462 CDS YP_003103190.1 256379530 8329732 6562341..6564236 1 NC_013093.1 TIGRFAM: YhgE/Pip C-terminal domain protein; YhgE/Pip N-terminal domain protein; PFAM: ABC transporter; KEGG: bce:BC5221 phage infection protein; YhgE/Pip C-terminal domain-containing protein 6564236 8329732 Amir_5526 Actinosynnema mirum DSM 43827 YhgE/Pip C-terminal domain-containing protein YP_003103190.1 6562341 D 446462 CDS YP_003103191.1 256379531 8329733 6564233..6564844 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 6564844 8329733 Amir_5527 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003103191.1 6564233 D 446462 CDS YP_003103192.1 256379532 8329734 complement(6564890..6565510) 1 NC_013093.1 KEGG: bcz:BCZK1848 short chain dehydrogenase; hypothetical protein 6565510 8329734 Amir_5528 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103192.1 6564890 R 446462 CDS YP_003103193.1 256379533 8329735 complement(6565585..6566193) 1 NC_013093.1 KEGG: cvi:CV_0278 hypothetical protein; hypothetical protein 6566193 8329735 Amir_5529 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103193.1 6565585 R 446462 CDS YP_003103194.1 256379534 8329736 complement(6566485..6567720) 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: NAD binding Rossmann fold oxidoreductase; K00540; oxidoreductase domain-containing protein 6567720 8329736 Amir_5530 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003103194.1 6566485 R 446462 CDS YP_003103195.1 256379535 8329737 complement(6567754..6567945) 1 NC_013093.1 KEGG: bur:Bcep18194_B0875 hypothetical protein; hypothetical protein 6567945 8329737 Amir_5531 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103195.1 6567754 R 446462 CDS YP_003103196.1 256379536 8329738 complement(6568951..6571617) 1 NC_013093.1 KEGG: afw:Anae109_2455 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; 3'-5' exonuclease; Helix-hairpin-helix domain protein class 2; DNA polymerase I 6571617 8329738 Amir_5532 Actinosynnema mirum DSM 43827 DNA polymerase I YP_003103196.1 6568951 R 446462 CDS YP_003103197.1 256379537 8329739 6571672..6572082 1 NC_013093.1 PFAM: thioesterase superfamily protein; KEGG: eum:ECUMN_0691 esterase; thioesterase superfamily protein 6572082 8329739 Amir_5533 Actinosynnema mirum DSM 43827 thioesterase superfamily protein YP_003103197.1 6571672 D 446462 CDS YP_003103198.1 256379538 8329740 6572087..6572605 1 NC_013093.1 KEGG: bcr:BCAH187_A1173 hypothetical protein; hypothetical protein 6572605 8329740 Amir_5534 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103198.1 6572087 D 446462 CDS YP_003103199.1 256379539 8329741 complement(6572684..6573388) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: gbm:Gbem_1946 ABC transporter protein; ABC transporter 6573388 8329741 Amir_5535 Actinosynnema mirum DSM 43827 ABC transporter YP_003103199.1 6572684 R 446462 CDS YP_003103200.1 256379540 8329742 complement(6573378..6574154) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bmj:BMULJ_02460 branched-chain amino acid transport system ATP-binding protein; ABC transporter 6574154 8329742 Amir_5536 Actinosynnema mirum DSM 43827 ABC transporter YP_003103200.1 6573378 R 446462 CDS YP_003103201.1 256379541 8329743 complement(6574151..6575308) 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: bbr:BB2027 ABC transport protein, ATP-binding component; inner-membrane translocator 6575308 8329743 Amir_5537 Actinosynnema mirum DSM 43827 inner-membrane translocator YP_003103201.1 6574151 R 446462 CDS YP_003103202.1 256379542 8329744 complement(6575305..6576267) 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: cvi:CV_1503 leucine/isoleucine/valine transport system permease protein; inner-membrane translocator 6576267 8329744 Amir_5538 Actinosynnema mirum DSM 43827 inner-membrane translocator YP_003103202.1 6575305 R 446462 CDS YP_003103203.1 256379543 8329745 complement(6576393..6577571) 1 NC_013093.1 PFAM: Extracellular ligand-binding receptor; KEGG: azo:azo3730 leucine-specific binding protein; Extracellular ligand-binding receptor 6577571 8329745 Amir_5539 Actinosynnema mirum DSM 43827 Extracellular ligand-binding receptor YP_003103203.1 6576393 R 446462 CDS YP_003103204.1 256379544 8329746 complement(6577885..6578487) 1 NC_013093.1 PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; KEGG: gme:Gmet_0660 response regulator receiver/ANTAR domain-containing protein; response regulator receiver and ANTAR domain-containing protein 6578487 8329746 Amir_5540 Actinosynnema mirum DSM 43827 response regulator receiver and ANTAR domain-containing protein YP_003103204.1 6577885 R 446462 CDS YP_003103205.1 256379545 8329747 complement(6579184..6580137) 1 NC_013093.1 hypothetical protein 6580137 8329747 Amir_5541 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103205.1 6579184 R 446462 CDS YP_003103206.1 256379546 8329748 6580562..6581077 1 NC_013093.1 PFAM: protein of unknown function DUF664; hypothetical protein 6581077 8329748 Amir_5542 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103206.1 6580562 D 446462 CDS YP_003103207.1 256379547 8329749 complement(6581555..6582871) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6582871 8329749 Amir_5543 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103207.1 6581555 R 446462 CDS YP_003103208.1 256379548 8329750 6582967..6583431 1 NC_013093.1 PFAM: CoA-binding domain protein; KEGG: mag:amb2851 hypothetical protein; CoA-binding domain-containing protein 6583431 8329750 Amir_5544 Actinosynnema mirum DSM 43827 CoA-binding domain-containing protein YP_003103208.1 6582967 D 446462 CDS YP_003103209.1 256379549 8329751 complement(6583409..6583789) 1 NC_013093.1 PFAM: endoribonuclease L-PSP; KEGG: nmu:Nmul_A2263 endoribonuclease L-PSP; endoribonuclease L-PSP 6583789 8329751 Amir_5545 Actinosynnema mirum DSM 43827 endoribonuclease L-PSP YP_003103209.1 6583409 R 446462 CDS YP_003103210.1 256379550 8329752 6583847..6584641 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: xau:Xaut_2294 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 6584641 8329752 Amir_5546 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003103210.1 6583847 D 446462 CDS YP_003103211.1 256379551 8329753 6585183..6587426 1 NC_013093.1 KEGG: disease resistance-responsive family protein / fibroin-related; signal transduction protein with Nacht domain 6587426 8329753 Amir_5547 Actinosynnema mirum DSM 43827 signal transduction protein with Nacht domain YP_003103211.1 6585183 D 446462 CDS YP_003103212.1 256379552 8329754 complement(6587522..6588352) 1 NC_013093.1 PFAM: pentapeptide repeat protein; KEGG: bat:BAS3175 pentapeptide repeat-containing protein; pentapeptide repeat-containing protein 6588352 8329754 Amir_5548 Actinosynnema mirum DSM 43827 pentapeptide repeat-containing protein YP_003103212.1 6587522 R 446462 CDS YP_003103213.1 256379553 8329755 complement(6588700..6590520) 1 NC_013093.1 KEGG: bpt:Bpet0900 DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; HRDC domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein; ATP-dependent DNA helicase RecQ 6590520 8329755 Amir_5549 Actinosynnema mirum DSM 43827 ATP-dependent DNA helicase RecQ YP_003103213.1 6588700 R 446462 CDS YP_003103214.1 256379554 8329756 complement(6590530..6591894) 1 NC_013093.1 KEGG: bat:BAS3517 hypothetical protein; hypothetical protein 6591894 8329756 Amir_5550 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103214.1 6590530 R 446462 CDS YP_003103215.1 256379555 8329757 6591979..6592734 1 NC_013093.1 KEGG: hypothetical protein; restriction endonuclease-like protein 6592734 8329757 Amir_5551 Actinosynnema mirum DSM 43827 restriction endonuclease-like protein YP_003103215.1 6591979 D 446462 CDS YP_003103216.1 256379556 8329758 complement(6592742..6593104) 1 NC_013093.1 hypothetical protein 6593104 8329758 Amir_5552 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103216.1 6592742 R 446462 CDS YP_003103217.1 256379557 8329759 6593140..6594543 1 NC_013093.1 KEGG: ade:Adeh_0244 LigA; hypothetical protein 6594543 8329759 Amir_5553 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103217.1 6593140 D 446462 CDS YP_003103218.1 256379558 8329760 6594572..6594829 1 NC_013093.1 hypothetical protein 6594829 8329760 Amir_5554 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103218.1 6594572 D 446462 CDS YP_003103219.1 256379559 8329761 complement(6594888..6595355) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 6595355 8329761 Amir_5555 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103219.1 6594888 R 446462 CDS YP_003103220.1 256379560 8329762 6595479..6595742 1 NC_013093.1 KEGG: cja:CJA_3805 helix-turn-helix domain protein; XRE family transcriptional regulator 6595742 8329762 Amir_5556 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103220.1 6595479 D 446462 CDS YP_003103221.1 256379561 8329763 6595742..6596194 1 NC_013093.1 hypothetical protein 6596194 8329763 Amir_5557 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103221.1 6595742 D 446462 CDS YP_003103222.1 256379562 8329764 6596267..6597244 1 NC_013093.1 hypothetical protein 6597244 8329764 Amir_5558 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103222.1 6596267 D 446462 CDS YP_003103223.1 256379563 8329765 6597241..6598422 1 NC_013093.1 hypothetical protein 6598422 8329765 Amir_5559 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103223.1 6597241 D 446462 CDS YP_003103224.1 256379564 8329766 6598616..6599356 1 NC_013093.1 hypothetical protein 6599356 8329766 Amir_5560 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103224.1 6598616 D 446462 CDS YP_003103225.1 256379565 8329767 6599353..6599703 1 NC_013093.1 hypothetical protein 6599703 8329767 Amir_5561 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103225.1 6599353 D 446462 CDS YP_003103226.1 256379566 8329768 6599775..6600209 1 NC_013093.1 PFAM: HNH endonuclease; KEGG: sus:Acid_3418 HNH endonuclease; HNH endonuclease 6600209 8329768 Amir_5562 Actinosynnema mirum DSM 43827 HNH endonuclease YP_003103226.1 6599775 D 446462 CDS YP_003103227.1 256379567 8329769 6600206..6600715 1 NC_013093.1 hypothetical protein 6600715 8329769 Amir_5563 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103227.1 6600206 D 446462 CDS YP_003103228.1 256379568 8329770 6600746..6601606 1 NC_013093.1 KEGG: similar to homologue to Drosophila photoreceptor protein calphotin; hypothetical protein 6601606 8329770 Amir_5564 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103228.1 6600746 D 446462 CDS YP_003103229.1 256379569 8329771 6601603..6601881 1 NC_013093.1 hypothetical protein 6601881 8329771 Amir_5565 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103229.1 6601603 D 446462 CDS YP_003103230.1 256379570 8329772 6602048..6602350 1 NC_013093.1 hypothetical protein 6602350 8329772 Amir_5566 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103230.1 6602048 D 446462 CDS YP_003103231.1 256379571 8329773 6602468..6602929 1 NC_013093.1 hypothetical protein 6602929 8329773 Amir_5567 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103231.1 6602468 D 446462 CDS YP_003103232.1 256379572 8329774 6603093..6603497 1 NC_013093.1 hypothetical protein 6603497 8329774 Amir_5568 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103232.1 6603093 D 446462 CDS YP_003103233.1 256379573 8329775 6603494..6604198 1 NC_013093.1 hypothetical protein 6604198 8329775 Amir_5569 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103233.1 6603494 D 446462 CDS YP_003103234.1 256379574 8329776 6604654..6604848 1 NC_013093.1 hypothetical protein 6604848 8329776 Amir_5570 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103234.1 6604654 D 446462 CDS YP_003103235.1 256379575 8329777 6604845..6605237 1 NC_013093.1 hypothetical protein 6605237 8329777 Amir_5571 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103235.1 6604845 D 446462 CDS YP_003103236.1 256379576 8329778 6605247..6606314 1 NC_013093.1 KEGG: ppg:PputGB1_3430 hypothetical protein; hypothetical protein 6606314 8329778 Amir_5572 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103236.1 6605247 D 446462 CDS YP_003103237.1 256379577 8329779 6606318..6606803 1 NC_013093.1 KEGG: aba:Acid345_1977 metallophosphoesterase; metallophosphoesterase 6606803 8329779 Amir_5573 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003103237.1 6606318 D 446462 CDS YP_003103238.1 256379578 8329780 6606806..6608296 1 NC_013093.1 PFAM: C-5 cytosine-specific DNA methylase; KEGG: vei:Veis_3654 C-5 cytosine-specific DNA methylase; C-5 cytosine-specific DNA methylase 6608296 8329780 Amir_5574 Actinosynnema mirum DSM 43827 C-5 cytosine-specific DNA methylase YP_003103238.1 6606806 D 446462 CDS YP_003103239.1 256379579 8329781 6608323..6609000 1 NC_013093.1 KEGG: mxa:MXAN_2991 adventurous gliding motility protein AglZ; hypothetical protein 6609000 8329781 Amir_5575 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103239.1 6608323 D 446462 CDS YP_003103240.1 256379580 8329782 6609004..6609198 1 NC_013093.1 hypothetical protein 6609198 8329782 Amir_5576 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103240.1 6609004 D 446462 CDS YP_003103241.1 256379581 8329783 6609275..6609589 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 6609589 8329783 Amir_5577 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003103241.1 6609275 D 446462 CDS YP_003103242.1 256379582 8329784 6609589..6610083 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6610083 8329784 Amir_5578 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103242.1 6609589 D 446462 CDS YP_003103243.1 256379583 8329785 6610080..6610670 1 NC_013093.1 hypothetical protein 6610670 8329785 Amir_5579 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103243.1 6610080 D 446462 CDS YP_003103244.1 256379584 8329786 6610667..6610762 1 NC_013093.1 hypothetical protein 6610762 8329786 Amir_5580 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103244.1 6610667 D 446462 CDS YP_003103245.1 256379585 8329787 6610772..6610969 1 NC_013093.1 hypothetical protein 6610969 8329787 Amir_5581 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103245.1 6610772 D 446462 CDS YP_003103246.1 256379586 8329788 6611025..6611285 1 NC_013093.1 hypothetical protein 6611285 8329788 Amir_5582 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103246.1 6611025 D 446462 CDS YP_003103247.1 256379587 8329789 6611322..6612224 1 NC_013093.1 KEGG: pzu:PHZ_c2649 5-methyltetrahydrofolate-- homocysteine methyltransferase; hypothetical protein 6612224 8329789 Amir_5583 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103247.1 6611322 D 446462 CDS YP_003103248.1 256379588 8329790 6612239..6612607 1 NC_013093.1 hypothetical protein 6612607 8329790 Amir_5584 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103248.1 6612239 D 446462 CDS YP_003103249.1 256379589 8329791 6612878..6613822 1 NC_013093.1 PFAM: hypothetical protein; KEGG: gme:Gmet_0890 smf protein; hypothetical protein 6613822 8329791 Amir_5585 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103249.1 6612878 D 446462 CDS YP_003103250.1 256379590 8329792 6613839..6614582 1 NC_013093.1 KEGG: dol:Dole_1907 phosphoribosyltransferase; phosphoribosyltransferase 6614582 8329792 Amir_5586 Actinosynnema mirum DSM 43827 phosphoribosyltransferase YP_003103250.1 6613839 D 446462 CDS YP_003103251.1 256379591 8329793 complement(6614684..6614878) 1 NC_013093.1 hypothetical protein 6614878 8329793 Amir_5587 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103251.1 6614684 R 446462 CDS YP_003103252.1 256379592 8329794 complement(6614878..6615633) 1 NC_013093.1 KEGG: GK12364 gene product from transcript GK12364- RA; hypothetical protein 6615633 8329794 Amir_5588 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103252.1 6614878 R 446462 CDS YP_003103253.1 256379593 8329795 complement(6615739..6615951) 1 NC_013093.1 hypothetical protein 6615951 8329795 Amir_5589 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103253.1 6615739 R 446462 CDS YP_003103254.1 256379594 8329796 complement(6615997..6616725) 1 NC_013093.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: gbe:GbCGDNIH1_1245 predicted membrane-bound metal-dependent hydrolase; membrane-bound metal-dependent hydrolase 6616725 8329796 Amir_5590 Actinosynnema mirum DSM 43827 membrane-bound metal-dependent hydrolase YP_003103254.1 6615997 R 446462 CDS YP_003103255.1 256379595 8329797 complement(6616857..6617591) 1 NC_013093.1 KEGG: fibrocystin-L-like protein; hypothetical protein 6617591 8329797 Amir_5591 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103255.1 6616857 R 446462 CDS YP_003103256.1 256379596 8329798 complement(6617855..6620113) 1 NC_013093.1 KEGG: ade:Adeh_4037 MaoC-like dehydratase; hypothetical protein 6620113 8329798 Amir_5592 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103256.1 6617855 R 446462 CDS YP_003103257.1 256379597 8329799 complement(6620176..6621246) 1 NC_013093.1 KEGG: PF6; flagellar central pair-associated protein; hypothetical protein 6621246 8329799 Amir_5593 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103257.1 6620176 R 446462 CDS YP_003103258.1 256379598 8329800 complement(6621246..6621689) 1 NC_013093.1 hypothetical protein 6621689 8329800 Amir_5594 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103258.1 6621246 R 446462 CDS YP_003103259.1 256379599 8329801 complement(6621701..6623071) 1 NC_013093.1 KEGG: pin:Ping_0445 colicin uptake-like protein; hypothetical protein 6623071 8329801 Amir_5595 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103259.1 6621701 R 446462 CDS YP_003103260.1 256379600 8329802 complement(6623132..6623800) 1 NC_013093.1 hypothetical protein 6623800 8329802 Amir_5596 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103260.1 6623132 R 446462 CDS YP_003103261.1 256379601 8329803 complement(6623869..6624387) 1 NC_013093.1 KEGG: scl:sce8592 hypothetical protein; hypothetical protein 6624387 8329803 Amir_5597 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103261.1 6623869 R 446462 CDS YP_003103262.1 256379602 8329804 complement(6624384..6624881) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: scl:sce2352 hypothetical protein; NUDIX hydrolase 6624881 8329804 Amir_5598 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003103262.1 6624384 R 446462 CDS YP_003103263.1 256379603 8329805 complement(6624973..6625239) 1 NC_013093.1 hypothetical protein 6625239 8329805 Amir_5599 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103263.1 6624973 R 446462 CDS YP_003103264.1 256379604 8329808 complement(6625791..6626732) 1 NC_013093.1 hypothetical protein 6626732 8329808 Amir_5602 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103264.1 6625791 R 446462 CDS YP_003103265.1 256379605 8329809 complement(6626809..6626967) 1 NC_013093.1 hypothetical protein 6626967 8329809 Amir_5603 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103265.1 6626809 R 446462 CDS YP_003103266.1 256379606 8329810 complement(6627012..6627218) 1 NC_013093.1 hypothetical protein 6627218 8329810 Amir_5604 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103266.1 6627012 R 446462 CDS YP_003103267.1 256379607 8329811 6627335..6628135 1 NC_013093.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sil:SPO0467 GntR family transcriptional regulator; GntR family transcriptional regulator 6628135 8329811 Amir_5605 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003103267.1 6627335 D 446462 CDS YP_003103268.1 256379608 8329812 6628276..6628458 1 NC_013093.1 hypothetical protein 6628458 8329812 Amir_5606 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103268.1 6628276 D 446462 CDS YP_003103269.1 256379609 8329813 6628549..6629106 1 NC_013093.1 hypothetical protein 6629106 8329813 Amir_5607 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103269.1 6628549 D 446462 CDS YP_003103270.1 256379610 8329814 6629103..6629558 1 NC_013093.1 hypothetical protein 6629558 8329814 Amir_5608 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103270.1 6629103 D 446462 CDS YP_003103271.1 256379611 8329815 6629882..6630007 1 NC_013093.1 hypothetical protein 6630007 8329815 Amir_5609 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103271.1 6629882 D 446462 CDS YP_003103272.1 256379612 8329816 6630039..6630329 1 NC_013093.1 hypothetical protein 6630329 8329816 Amir_5610 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103272.1 6630039 D 446462 CDS YP_003103273.1 256379613 8329817 6630791..6632560 1 NC_013093.1 PFAM: lipolytic protein G-D-S-L family; KEGG: met:M446_3487 triple helix repeat-containing COllagen; G-D-S-L family lipolytic protein 6632560 8329817 Amir_5611 Actinosynnema mirum DSM 43827 G-D-S-L family lipolytic protein YP_003103273.1 6630791 D 446462 CDS YP_003103274.1 256379614 8329818 6632577..6632963 1 NC_013093.1 KEGG: bav:BAV1457 phage protein; phage protein 6632963 8329818 Amir_5612 Actinosynnema mirum DSM 43827 phage protein YP_003103274.1 6632577 D 446462 CDS YP_003103275.1 256379615 8329819 6632974..6633249 1 NC_013093.1 hypothetical protein 6633249 8329819 Amir_5613 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103275.1 6632974 D 446462 CDS YP_003103276.1 256379616 8329820 6633246..6633665 1 NC_013093.1 hypothetical protein 6633665 8329820 Amir_5614 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103276.1 6633246 D 446462 CDS YP_003103277.1 256379617 8329821 6633662..6634258 1 NC_013093.1 KEGG: nwi:Nwi_1556 hypothetical protein; hypothetical protein 6634258 8329821 Amir_5615 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103277.1 6633662 D 446462 CDS YP_003103278.1 256379618 8329822 6634262..6634528 1 NC_013093.1 hypothetical protein 6634528 8329822 Amir_5616 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103278.1 6634262 D 446462 CDS YP_003103279.1 256379619 8329823 6634515..6634727 1 NC_013093.1 hypothetical protein 6634727 8329823 Amir_5617 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103279.1 6634515 D 446462 CDS YP_003103280.1 256379620 8329824 6634986..6635186 1 NC_013093.1 hypothetical protein 6635186 8329824 Amir_5618 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103280.1 6634986 D 446462 CDS YP_003103281.1 256379621 8329825 6635186..6635635 1 NC_013093.1 hypothetical protein 6635635 8329825 Amir_5619 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103281.1 6635186 D 446462 CDS YP_003103282.1 256379622 8329826 6635632..6637245 1 NC_013093.1 PFAM: terminase; KEGG: acp:A2cp1_1302 terminase; terminase 6637245 8329826 Amir_5620 Actinosynnema mirum DSM 43827 terminase YP_003103282.1 6635632 D 446462 CDS YP_003103283.1 256379623 8329827 6637256..6638680 1 NC_013093.1 PFAM: protein of unknown function DUF1483; hypothetical protein 6638680 8329827 Amir_5621 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103283.1 6637256 D 446462 CDS YP_003103284.1 256379624 8329828 6638677..6639720 1 NC_013093.1 hypothetical protein 6639720 8329828 Amir_5622 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103284.1 6638677 D 446462 CDS YP_003103285.1 256379625 8329829 6639767..6640432 1 NC_013093.1 KEGG: dal:Dalk_5199 hypothetical protein; hypothetical protein 6640432 8329829 Amir_5623 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103285.1 6639767 D 446462 CDS YP_003103286.1 256379626 8329830 6640429..6640620 1 NC_013093.1 hypothetical protein 6640620 8329830 Amir_5624 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103286.1 6640429 D 446462 CDS YP_003103287.1 256379627 8329831 6640620..6641975 1 NC_013093.1 KEGG: acr:Acry_2510 hypothetical protein; hypothetical protein 6641975 8329831 Amir_5625 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103287.1 6640620 D 446462 CDS YP_003103288.1 256379628 8329832 6641975..6642439 1 NC_013093.1 KEGG: bpa:BPP1618 autotransporter; hypothetical protein 6642439 8329832 Amir_5626 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103288.1 6641975 D 446462 CDS YP_003103289.1 256379629 8329833 6642450..6643067 1 NC_013093.1 hypothetical protein 6643067 8329833 Amir_5627 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103289.1 6642450 D 446462 CDS YP_003103290.1 256379630 8329834 6643199..6643567 1 NC_013093.1 hypothetical protein 6643567 8329834 Amir_5628 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103290.1 6643199 D 446462 CDS YP_003103291.1 256379631 8329835 6643577..6643900 1 NC_013093.1 hypothetical protein 6643900 8329835 Amir_5629 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103291.1 6643577 D 446462 CDS YP_003103292.1 256379632 8329836 6643903..6644205 1 NC_013093.1 hypothetical protein 6644205 8329836 Amir_5630 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103292.1 6643903 D 446462 CDS YP_003103293.1 256379633 8329837 6644215..6644649 1 NC_013093.1 hypothetical protein 6644649 8329837 Amir_5631 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103293.1 6644215 D 446462 CDS YP_003103294.1 256379634 8329838 6644788..6645339 1 NC_013093.1 hypothetical protein 6645339 8329838 Amir_5632 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103294.1 6644788 D 446462 CDS YP_003103295.1 256379635 8329839 6645354..6645725 1 NC_013093.1 hypothetical protein 6645725 8329839 Amir_5633 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103295.1 6645354 D 446462 CDS YP_003103296.1 256379636 8329840 6645812..6646225 1 NC_013093.1 hypothetical protein 6646225 8329840 Amir_5634 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103296.1 6645812 D 446462 CDS YP_003103297.1 256379637 8329841 6646242..6650357 1 NC_013093.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: mgm:Mmc1_2034 phage tail tape measure protein, TP901 family; phage tail tape measure protein, TP901 family 6650357 8329841 Amir_5635 Actinosynnema mirum DSM 43827 phage tail tape measure protein, TP901 family YP_003103297.1 6646242 D 446462 CDS YP_003103298.1 256379638 8329842 6650368..6651813 1 NC_013093.1 KEGG: similar to endo-1,4-beta-glucanase; hypothetical protein 6651813 8329842 Amir_5636 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103298.1 6650368 D 446462 CDS YP_003103299.1 256379639 8329843 6651863..6652993 1 NC_013093.1 KEGG: mag:amb1782 PRY3 protein; hypothetical protein 6652993 8329843 Amir_5637 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103299.1 6651863 D 446462 CDS YP_003103300.1 256379640 8329844 6652990..6654129 1 NC_013093.1 hypothetical protein 6654129 8329844 Amir_5638 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103300.1 6652990 D 446462 CDS YP_003103301.1 256379641 8329845 6654129..6654839 1 NC_013093.1 hypothetical protein 6654839 8329845 Amir_5639 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103301.1 6654129 D 446462 CDS YP_003103302.1 256379642 8329846 complement(6654840..6655265) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6655265 8329846 Amir_5640 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103302.1 6654840 R 446462 CDS YP_003103303.1 256379643 8329847 6655352..6655609 1 NC_013093.1 hypothetical protein 6655609 8329847 Amir_5641 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103303.1 6655352 D 446462 CDS YP_003103304.1 256379644 8329848 6655606..6655986 1 NC_013093.1 hypothetical protein 6655986 8329848 Amir_5642 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103304.1 6655606 D 446462 CDS YP_003103305.1 256379645 8329849 6655983..6656990 1 NC_013093.1 PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; KEGG: sil:SPO3258 glycosy hydrolase family protein; glycoside hydrolase family protein 6656990 8329849 Amir_5643 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003103305.1 6655983 D 446462 CDS YP_003103306.1 256379646 8329850 6656987..6658045 1 NC_013093.1 hypothetical protein 6658045 8329850 Amir_5644 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103306.1 6656987 D 446462 CDS YP_003103307.1 256379647 8329852 6658454..6658687 1 NC_013093.1 KEGG: psb:Psyr_2800 hypothetical protein; hypothetical protein 6658687 8329852 Amir_5646 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103307.1 6658454 D 446462 CDS YP_003103308.1 256379648 8329853 complement(6658747..6659979) 1 NC_013093.1 PFAM: integrase family protein; KEGG: bce:BC1272 DNA integration/recombination/invertion protein; integrase family protein 6659979 8329853 Amir_5647 Actinosynnema mirum DSM 43827 integrase family protein YP_003103308.1 6658747 R 446462 CDS YP_003103309.1 256379649 8329855 complement(6660208..6660489) 1 NC_013093.1 PFAM: protein of unknown function DUF156; KEGG: acp:A2cp1_3648 protein of unknown function DUF156; hypothetical protein 6660489 8329855 Amir_5648 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103309.1 6660208 R 446462 CDS YP_003103310.1 256379650 8329856 6660753..6661094 1 NC_013093.1 hypothetical protein 6661094 8329856 Amir_5649 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103310.1 6660753 D 446462 CDS YP_003103311.1 256379651 8329857 complement(6661156..6663174) 1 NC_013093.1 TIGRFAM: para-aminobenzoate synthase, subunit I; glutamine amidotransferase of anthranilate synthase; PFAM: Chorismate binding-like; glutamine amidotransferase class-I; Anthranilate synthase component I domain protein; KEGG: rpd:RPD_2897 para-aminobenzoate synthase, component I; para-aminobenzoate synthase, subunit I 6663174 8329857 Amir_5650 Actinosynnema mirum DSM 43827 para-aminobenzoate synthase, subunit I YP_003103311.1 6661156 R 446462 CDS YP_003103312.1 256379652 8329858 complement(6663234..6663959) 1 NC_013093.1 hypothetical protein 6663959 8329858 Amir_5651 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103312.1 6663234 R 446462 CDS YP_003103313.1 256379653 8329859 complement(6663953..6664453) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: pca:Pcar_3124 RNA polymerase, sigma-E factor; ECF subfamily RNA polymerase sigma-24 subunit 6664453 8329859 Amir_5652 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103313.1 6663953 R 446462 CDS YP_003103314.1 256379654 8329860 6664572..6665831 1 NC_013093.1 PFAM: metallophosphoesterase; KEGG: scl:sce7577 integral membrane protein; metallophosphoesterase 6665831 8329860 Amir_5653 Actinosynnema mirum DSM 43827 metallophosphoesterase YP_003103314.1 6664572 D 446462 CDS YP_003103315.1 256379655 8329861 6665882..6667075 1 NC_013093.1 PFAM: Orn/DAP/Arg decarboxylase 2; alanine racemase domain protein; KEGG: mag:amb1388 diaminopimelate decarboxylase; Orn/DAP/Arg decarboxylase 2 6667075 8329861 Amir_5654 Actinosynnema mirum DSM 43827 Orn/DAP/Arg decarboxylase 2 YP_003103315.1 6665882 D 446462 CDS YP_003103316.1 256379656 8329862 6667146..6667559 1 NC_013093.1 TIGRFAM: S-adenosylmethionine decarboxylase proenzyme; PFAM: S-adenosylmethionine decarboxylase related; KEGG: bcr:BCAH187_A5378 adenosylmethionine decarboxylase 2; S-adenosylmethionine decarboxylase proenzyme 6667559 8329862 Amir_5655 Actinosynnema mirum DSM 43827 S-adenosylmethionine decarboxylase proenzyme YP_003103316.1 6667146 D 446462 CDS YP_003103317.1 256379657 8329863 6667556..6668401 1 NC_013093.1 PFAM: spermine synthase; KEGG: jan:Jann_0855 spermidine synthase; spermine synthase 6668401 8329863 Amir_5656 Actinosynnema mirum DSM 43827 spermine synthase YP_003103317.1 6667556 D 446462 CDS YP_003103318.1 256379658 8329864 complement(6668504..6670585) 1 NC_013093.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: afw:Anae109_2431 peptidase S9B dipeptidylpeptidase IV subunit; peptidase S9 prolyl oligopeptidase active site domain-containing protein 6670585 8329864 Amir_5657 Actinosynnema mirum DSM 43827 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_003103318.1 6668504 R 446462 CDS YP_003103319.1 256379659 8329865 complement(6670710..6671315) 1 NC_013093.1 PFAM: nitroreductase; KEGG: lch:Lcho_1290 nitroreductase; hypothetical protein 6671315 8329865 Amir_5658 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103319.1 6670710 R 446462 CDS YP_003103320.1 256379660 8329866 complement(6671480..6672745) 1 NC_013093.1 PFAM: glycine hydroxymethyltransferase; aminotransferase class I and II; aromatic amino acid beta- eliminating lyase/threonine aldolase; KEGG: rce:RC1_1342 serine hydroxymethyltransferase; glycine hydroxymethyltransferase 6672745 8329866 Amir_5659 Actinosynnema mirum DSM 43827 glycine hydroxymethyltransferase YP_003103320.1 6671480 R 446462 CDS YP_003103321.1 256379661 8329867 complement(6672763..6673860) 1 NC_013093.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 6673860 gcvT 8329867 gcvT Actinosynnema mirum DSM 43827 glycine cleavage system aminomethyltransferase T YP_003103321.1 6672763 R 446462 CDS YP_003103322.1 256379662 8329868 complement(6674048..6674350) 1 NC_013093.1 KEGG: bba:Bd3290 hypothetical protein; hypothetical protein 6674350 8329868 Amir_5661 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103322.1 6674048 R 446462 CDS YP_003103323.1 256379663 8329869 complement(6674374..6674844) 1 NC_013093.1 glucitol operon activator-like protein 6674844 8329869 Amir_5662 Actinosynnema mirum DSM 43827 glucitol operon activator-like protein YP_003103323.1 6674374 R 446462 CDS YP_003103324.1 256379664 8329870 complement(6675471..6675962) 1 NC_013093.1 hypothetical protein 6675962 8329870 Amir_5663 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103324.1 6675471 R 446462 CDS YP_003103325.1 256379665 8329871 complement(6676142..6676288) 1 NC_013093.1 hypothetical protein 6676288 8329871 Amir_5664 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103325.1 6676142 R 446462 CDS YP_003103326.1 256379666 8329872 complement(6677645..6678766) 1 NC_013093.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rfr:Rfer_0993 L-carnitine dehydratase/bile acid-inducible protein F; L-carnitine dehydratase/bile acid-inducible protein F 6678766 8329872 Amir_5665 Actinosynnema mirum DSM 43827 L-carnitine dehydratase/bile acid-inducible protein F YP_003103326.1 6677645 R 446462 CDS YP_003103327.1 256379667 8329873 complement(6678766..6679911) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: rce:RC1_0378 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 6679911 8329873 Amir_5666 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003103327.1 6678766 R 446462 CDS YP_003103328.1 256379668 8329874 6679981..6680553 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: swp:swp_4165 GCN5-like N-acetyltransferase; GCN5-like N-acetyltransferase 6680553 8329874 Amir_5667 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103328.1 6679981 D 446462 CDS YP_003103329.1 256379669 8329875 6680614..6681816 1 NC_013093.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: pag:PLES_35931 acyl-CoA thiolase; acetyl-CoA acetyltransferase 6681816 8329875 Amir_5668 Actinosynnema mirum DSM 43827 acetyl-CoA acetyltransferase YP_003103329.1 6680614 D 446462 CDS YP_003103330.1 256379670 8329876 6681818..6683872 1 NC_013093.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: pmy:Pmen_2590 short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase 6683872 8329876 Amir_5669 Actinosynnema mirum DSM 43827 3-hydroxyacyl-CoA dehydrogenase YP_003103330.1 6681818 D 446462 CDS YP_003103331.1 256379671 8329877 complement(6683863..6684870) 1 NC_013093.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pmy:Pmen_2972 AraC family transcriptional regulator; AraC family transcriptional regulator 6684870 8329877 Amir_5670 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003103331.1 6683863 R 446462 CDS YP_003103332.1 256379672 8329878 6685400..6685795 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6685795 8329878 Amir_5671 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103332.1 6685400 D 446462 CDS YP_003103333.1 256379673 8329879 6686089..6687207 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; amino acid- binding ACT domain protein; KEGG: mch:Mchl_1293 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 6687207 8329879 Amir_5672 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103333.1 6686089 D 446462 CDS YP_003103334.1 256379674 8329880 6687607..6688638 1 NC_013093.1 KEGG: vvy:VVA0123 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 6688638 8329880 Amir_5673 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003103334.1 6687607 D 446462 CDS YP_003103335.1 256379675 8329881 complement(6689046..6691562) 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: aeh:Mlg_1312 hypothetical protein; hypothetical protein 6691562 8329881 Amir_5674 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103335.1 6689046 R 446462 CDS YP_003103336.1 256379676 8329882 complement(6691562..6692314) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0970 ABC transporter, ATPase subunit; ABC transporter 6692314 8329882 Amir_5675 Actinosynnema mirum DSM 43827 ABC transporter YP_003103336.1 6691562 R 446462 CDS YP_003103337.1 256379677 8329883 complement(6692533..6695394) 1 NC_013093.1 PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; ATPase AAA; KEGG: rlt:Rleg2_5436 transcriptional regulator, LuxR family; LuxR family transcriptional regulator 6695394 8329883 Amir_5676 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003103337.1 6692533 R 446462 CDS YP_003103338.1 256379678 8329884 complement(6695531..6698428) 1 NC_013093.1 PFAM: transcriptional activator domain; TPR repeat- containing protein; NB-ARC domain protein; transcriptional regulator domain protein; SMART: hypothetical protein; KEGG: scl:sce3550 hypothetical protein; SARP family transcriptional regulator 6698428 8329884 Amir_5677 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003103338.1 6695531 R 446462 CDS YP_003103339.1 256379679 8329885 complement(6698964..6699629) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: ssn:SSON_2375 hypothetical protein; hypothetical protein 6699629 8329885 Amir_5678 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103339.1 6698964 R 446462 CDS YP_003103340.1 256379680 8329886 complement(6699936..6700127) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 6700127 8329886 Amir_5679 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103340.1 6699936 R 446462 CDS YP_003103341.1 256379681 8329887 complement(6700146..6700994) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 6700994 8329887 Amir_5680 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103341.1 6700146 R 446462 CDS YP_003103342.1 256379682 8329888 6701169..6701549 1 NC_013093.1 hypothetical protein 6701549 8329888 Amir_5681 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103342.1 6701169 D 446462 CDS YP_003103343.1 256379683 8329889 6701944..6704163 1 NC_013093.1 PFAM: carbonic anhydrase; sulphate transporter; xanthine/uracil/vitamin C permease; KEGG: mxa:MXAN_4784 inorganic anion transporter, sulfate permease (SulP) family; carbonate dehydratase 6704163 8329889 Amir_5682 Actinosynnema mirum DSM 43827 carbonate dehydratase YP_003103343.1 6701944 D 446462 CDS YP_003103344.1 256379684 8329890 complement(6704244..6705683) 1 NC_013093.1 TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: bsu:BSU23860 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase 6705683 8329890 Amir_5683 Actinosynnema mirum DSM 43827 6-phosphogluconate dehydrogenase YP_003103344.1 6704244 R 446462 CDS YP_003103345.1 256379685 8329891 complement(6705946..6707874) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: hypothetical protein; ECF subfamily RNA polymerase sigma-24 subunit 6707874 8329891 Amir_5684 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103345.1 6705946 R 446462 CDS YP_003103346.1 256379686 8329892 6707962..6709350 1 NC_013093.1 PFAM: pyridoxal-dependent decarboxylase; KEGG: aba:Acid345_2160 aromatic-L-amino-acid decarboxylase; Aromatic-L-amino-acid decarboxylase 6709350 8329892 Amir_5685 Actinosynnema mirum DSM 43827 Aromatic-L-amino-acid decarboxylase YP_003103346.1 6707962 D 446462 CDS YP_003103347.1 256379687 8329893 complement(6709518..6710450) 1 NC_013093.1 KEGG: met:M446_5500 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; acyl-CoA thioesterase II 6710450 8329893 Amir_5686 Actinosynnema mirum DSM 43827 acyl-CoA thioesterase II YP_003103347.1 6709518 R 446462 CDS YP_003103348.1 256379688 8329894 complement(6710466..6711890) 1 NC_013093.1 KEGG: gur:Gura_4409 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; pyruvate kinase 6711890 8329894 Amir_5687 Actinosynnema mirum DSM 43827 pyruvate kinase YP_003103348.1 6710466 R 446462 CDS YP_003103349.1 256379689 8329895 6711976..6712335 1 NC_013093.1 PFAM: VanZ family protein; KEGG: jan:Jann_0771 VanZ like protein; VanZ family protein 6712335 8329895 Amir_5688 Actinosynnema mirum DSM 43827 VanZ family protein YP_003103349.1 6711976 D 446462 CDS YP_003103350.1 256379690 8329896 complement(6712420..6713076) 1 NC_013093.1 KEGG: hch:HCH_00125 hypothetical protein; hypothetical protein 6713076 8329896 Amir_5689 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103350.1 6712420 R 446462 CDS YP_003103351.1 256379691 8329897 complement(6713371..6714273) 1 NC_013093.1 hypothetical protein 6714273 8329897 Amir_5690 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103351.1 6713371 R 446462 CDS YP_003103352.1 256379692 8329898 complement(6714380..6715741) 1 NC_013093.1 KEGG: xau:Xaut_0919 leucine-rich repeat-containing protein; hypothetical protein 6715741 8329898 Amir_5691 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103352.1 6714380 R 446462 CDS YP_003103353.1 256379693 8329899 complement(6716066..6717568) 1 NC_013093.1 TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: sus:Acid_3815 glutamate synthase (NADH) small subunit; glutamate synthase, NADH/NADPH, small subunit 6717568 8329899 Amir_5692 Actinosynnema mirum DSM 43827 glutamate synthase, NADH/NADPH, small subunit YP_003103353.1 6716066 R 446462 CDS YP_003103354.1 256379694 8329900 complement(6717561..6722099) 1 NC_013093.1 PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin); glutamate synthase (ferredoxin) 6722099 8329900 Amir_5693 Actinosynnema mirum DSM 43827 glutamate synthase (ferredoxin) YP_003103354.1 6717561 R 446462 CDS YP_003103355.1 256379695 8329901 complement(6723006..6724376) 1 NC_013093.1 PFAM: sodium:dicarboxylate symporter; KEGG: gur:Gura_0381 sodium:dicarboxylate symporter; sodium:dicarboxylate symporter 6724376 8329901 Amir_5694 Actinosynnema mirum DSM 43827 sodium:dicarboxylate symporter YP_003103355.1 6723006 R 446462 CDS YP_003103356.1 256379696 8329902 6724957..6725883 1 NC_013093.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: sfu:Sfum_3723 TRAP transporter solute receptor, TAXI family; TRAP transporter solute receptor, TAXI family 6725883 8329902 Amir_5695 Actinosynnema mirum DSM 43827 TRAP transporter solute receptor, TAXI family YP_003103356.1 6724957 D 446462 CDS YP_003103357.1 256379697 8329903 complement(6726232..6727599) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_0328 ATPase domain-containing protein; histidine kinase 6727599 8329903 Amir_5696 Actinosynnema mirum DSM 43827 histidine kinase YP_003103357.1 6726232 R 446462 CDS YP_003103358.1 256379698 8329904 6727708..6728274 1 NC_013093.1 KEGG: scl:sce7916 hypothetical protein; hypothetical protein 6728274 8329904 Amir_5697 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103358.1 6727708 D 446462 CDS YP_003103359.1 256379699 8329905 complement(6728338..6729006) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: ade:Adeh_3856 two component transcriptional regulator; winged helix family two component transcriptional regulator 6729006 8329905 Amir_5698 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003103359.1 6728338 R 446462 CDS YP_003103360.1 256379700 8329906 complement(6729013..6730128) 1 NC_013093.1 TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; KEGG: bha:BH3589 prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase 6730128 8329906 Amir_5699 Actinosynnema mirum DSM 43827 prolipoprotein diacylglyceryl transferase YP_003103360.1 6729013 R 446462 CDS YP_003103361.1 256379701 8329907 complement(6730301..6731086) 1 NC_013093.1 KEGG: acp:A2cp1_4201 tryptophan synthase, alpha subunit; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain; tryptophan synthase subunit alpha 6731086 8329907 Amir_5700 Actinosynnema mirum DSM 43827 tryptophan synthase subunit alpha YP_003103361.1 6730301 R 446462 CDS YP_003103362.1 256379702 8329908 complement(6731083..6732318) 1 NC_013093.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 6732318 8329908 Amir_5701 Actinosynnema mirum DSM 43827 tryptophan synthase subunit beta YP_003103362.1 6731083 R 446462 CDS YP_003103363.1 256379703 8329909 complement(6732330..6733145) 1 NC_013093.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 6733145 trpC 8329909 trpC Actinosynnema mirum DSM 43827 indole-3-glycerol-phosphate synthase YP_003103363.1 6732330 R 446462 CDS YP_003103364.1 256379704 8329910 complement(6733361..6733993) 1 NC_013093.1 KEGG: azo:azo0239 hypothetical protein; hypothetical protein 6733993 8329910 Amir_5703 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103364.1 6733361 R 446462 CDS YP_003103365.1 256379705 8329911 complement(6734079..6735620) 1 NC_013093.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 6735620 8329911 Amir_5704 Actinosynnema mirum DSM 43827 anthranilate synthase component I YP_003103365.1 6734079 R 446462 CDS YP_003103366.1 256379706 8329912 6735739..6736401 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mlo:mlr3851 TetR family transcriptional regulator; TetR family transcriptional regulator 6736401 8329912 Amir_5705 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003103366.1 6735739 D 446462 CDS YP_003103367.1 256379707 8329913 complement(6736326..6736700) 1 NC_013093.1 PFAM: phosphoribosyl-AMP cyclohydrolase; KEGG: mag:amb2307 phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-AMP cyclohydrolase 6736700 8329913 Amir_5706 Actinosynnema mirum DSM 43827 phosphoribosyl-AMP cyclohydrolase YP_003103367.1 6736326 R 446462 CDS YP_003103368.1 256379708 8329914 complement(6736700..6737062) 1 NC_013093.1 KEGG: pen:PSEEN4801 sensor histidine kinase; hypothetical protein 6737062 8329914 Amir_5707 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103368.1 6736700 R 446462 CDS YP_003103369.1 256379709 8329915 complement(6737062..6737835) 1 NC_013093.1 TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; KEGG: rce:RC1_3299 imidazoleglycerol phosphate synthase, cyclase subunit; imidazoleglycerol phosphate synthase, cyclase subunit 6737835 8329915 Amir_5708 Actinosynnema mirum DSM 43827 imidazoleglycerol phosphate synthase, cyclase subunit YP_003103369.1 6737062 R 446462 CDS YP_003103370.1 256379710 8329916 complement(6737946..6738335) 1 NC_013093.1 TIGRFAM: death-on-curing family protein; PFAM: filamentation induced by cAMP protein Fic; KEGG: pla:Plav_1338 death-on-curing family protein; death-on-curing family protein 6738335 8329916 Amir_5709 Actinosynnema mirum DSM 43827 death-on-curing family protein YP_003103370.1 6737946 R 446462 CDS YP_003103371.1 256379711 8329917 6738459..6738827 1 NC_013093.1 hypothetical protein 6738827 8329917 Amir_5710 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103371.1 6738459 D 446462 CDS YP_003103372.1 256379712 8329918 6738866..6739588 1 NC_013093.1 PFAM: Clp domain protein; KEGG: Os12g0230100; hypothetical protein; K03696 ATP-dependent Clp protease ATP-binding subunit ClpC; Clp domain-containing protein 6739588 8329918 Amir_5711 Actinosynnema mirum DSM 43827 Clp domain-containing protein YP_003103372.1 6738866 D 446462 CDS YP_003103373.1 256379713 8329919 complement(6739551..6740285) 1 NC_013093.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A 6740285 8329919 Amir_5712 Actinosynnema mirum DSM 43827 phosphoribosyl isomerase A YP_003103373.1 6739551 R 446462 CDS YP_003103374.1 256379714 8329920 complement(6740335..6740967) 1 NC_013093.1 TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; KEGG: xau:Xaut_2291 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 6740967 8329920 Amir_5713 Actinosynnema mirum DSM 43827 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_003103374.1 6740335 R 446462 CDS YP_003103375.1 256379715 8329921 complement(6740978..6741466) 1 NC_013093.1 hypothetical protein 6741466 8329921 Amir_5714 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103375.1 6740978 R 446462 CDS YP_003103376.1 256379716 8329922 complement(6741504..6742394) 1 NC_013093.1 PFAM: transketolase; transketolase; KEGG: rpe:RPE_1518 transketolase, central region; transketolase 6742394 8329922 Amir_5715 Actinosynnema mirum DSM 43827 transketolase YP_003103376.1 6741504 R 446462 CDS YP_003103377.1 256379717 8329923 complement(6742391..6743077) 1 NC_013093.1 PFAM: transketolase; KEGG: bja:blr5426 transketolase; transketolase 6743077 8329923 Amir_5716 Actinosynnema mirum DSM 43827 transketolase YP_003103377.1 6742391 R 446462 CDS YP_003103378.1 256379718 8329924 6743101..6743592 1 NC_013093.1 KEGG: aav:Aave_2276 transcriptional regulator, MerR family; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR; MerR family transcriptional regulator 6743592 8329924 Amir_5717 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003103378.1 6743101 D 446462 CDS YP_003103379.1 256379719 8329925 6743603..6744127 1 NC_013093.1 PFAM: phosphotransferase KptA/Tpt1; KEGG: rle:RL2607 RNA 2'-phosphotransferase; phosphotransferase KptA/Tpt1 6744127 8329925 Amir_5718 Actinosynnema mirum DSM 43827 phosphotransferase KptA/Tpt1 YP_003103379.1 6743603 D 446462 CDS YP_003103380.1 256379720 8329926 complement(6744177..6744317) 1 NC_013093.1 hypothetical protein 6744317 8329926 Amir_5719 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103380.1 6744177 R 446462 CDS YP_003103381.1 256379721 8329927 complement(6744333..6744935) 1 NC_013093.1 PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: acr:Acry_1413 imidazoleglycerol-phosphate dehydratase; imidazoleglycerol-phosphate dehydratase 6744935 8329927 Amir_5720 Actinosynnema mirum DSM 43827 imidazoleglycerol-phosphate dehydratase YP_003103381.1 6744333 R 446462 CDS YP_003103382.1 256379722 8329928 complement(6744932..6746083) 1 NC_013093.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 6746083 8329928 Amir_5721 Actinosynnema mirum DSM 43827 histidinol-phosphate aminotransferase YP_003103382.1 6744932 R 446462 CDS YP_003103383.1 256379723 8329929 complement(6746080..6747396) 1 NC_013093.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 6747396 hisD 8329929 hisD Actinosynnema mirum DSM 43827 histidinol dehydrogenase YP_003103383.1 6746080 R 446462 CDS YP_003103384.1 256379724 8329930 6747591..6748910 1 NC_013093.1 PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; KEGG: bba:Bd3234 carboxypeptidase T precursor; peptidase M14 carboxypeptidase A 6748910 8329930 Amir_5723 Actinosynnema mirum DSM 43827 peptidase M14 carboxypeptidase A YP_003103384.1 6747591 D 446462 CDS YP_003103385.1 256379725 8329931 complement(6749030..6750211) 1 NC_013093.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce8911 class-V aminotransferase; class V aminotransferase 6750211 8329931 Amir_5724 Actinosynnema mirum DSM 43827 class V aminotransferase YP_003103385.1 6749030 R 446462 CDS YP_003103386.1 256379726 8329932 complement(6750196..6751755) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: ses:SARI_01727 hypothetical protein; family 5 extracellular solute-binding protein 6751755 8329932 Amir_5725 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003103386.1 6750196 R 446462 CDS YP_003103387.1 256379727 8329933 6751772..6752551 1 NC_013093.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eta:ETA_23610 hydrolase; nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase 6752551 8329933 Amir_5726 Actinosynnema mirum DSM 43827 nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase YP_003103387.1 6751772 D 446462 CDS YP_003103388.1 256379728 8329934 6752703..6753140 1 NC_013093.1 PFAM: PRC-barrel domain protein; KEGG: atc:AGR_C_723 hypothetical protein; PRC-barrel domain-containing protein 6753140 8329934 Amir_5727 Actinosynnema mirum DSM 43827 PRC-barrel domain-containing protein YP_003103388.1 6752703 D 446462 CDS YP_003103389.1 256379729 8329935 complement(6753345..6754208) 1 NC_013093.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 6754208 8329935 Amir_5728 Actinosynnema mirum DSM 43827 nicotinate-nucleotide pyrophosphorylase YP_003103389.1 6753345 R 446462 CDS YP_003103390.1 256379730 8329936 complement(6754288..6755904) 1 NC_013093.1 KEGG: sus:Acid_7341 L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; L-aspartate oxidase 6755904 8329936 Amir_5729 Actinosynnema mirum DSM 43827 L-aspartate oxidase YP_003103390.1 6754288 R 446462 CDS YP_003103391.1 256379731 8329937 complement(6755901..6756920) 1 NC_013093.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 6756920 8329937 Amir_5730 Actinosynnema mirum DSM 43827 quinolinate synthetase YP_003103391.1 6755901 R 446462 CDS YP_003103392.1 256379732 8329938 6756994..6757683 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: dal:Dalk_4948 NUDIX hydrolase; NUDIX hydrolase 6757683 8329938 Amir_5731 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003103392.1 6756994 D 446462 CDS YP_003103393.1 256379733 8329939 6757680..6758360 1 NC_013093.1 PFAM: peptidase S16 lon domain protein; SMART: peptidase S16 lon domain protein; KEGG: pau:PA14_11940 hypothetical protein; peptidase S16 lon domain-containing protein 6758360 8329939 Amir_5732 Actinosynnema mirum DSM 43827 peptidase S16 lon domain-containing protein YP_003103393.1 6757680 D 446462 CDS YP_003103394.1 256379734 8329941 6759781..6761052 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: cti:RALTA_B1248 muconolactone transporter; major facilitator superfamily MFS_1; major facilitator superfamily protein 6761052 8329941 Amir_5734 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003103394.1 6759781 D 446462 CDS YP_003103395.1 256379735 8329942 6761141..6761896 1 NC_013093.1 PFAM: protein of unknown function DUF1445; KEGG: pde:Pden_0321 hypothetical protein; hypothetical protein 6761896 8329942 Amir_5735 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103395.1 6761141 D 446462 CDS YP_003103396.1 256379736 8329943 complement(6761903..6763198) 1 NC_013093.1 KEGG: trans-sialidase; hypothetical protein 6763198 8329943 Amir_5736 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103396.1 6761903 R 446462 CDS YP_003103397.1 256379737 8329944 complement(6763292..6763489) 1 NC_013093.1 hypothetical protein 6763489 8329944 Amir_5737 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103397.1 6763292 R 446462 CDS YP_003103398.1 256379738 8329945 complement(6763486..6764529) 1 NC_013093.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase 6764529 8329945 Amir_5738 Actinosynnema mirum DSM 43827 biotin synthase YP_003103398.1 6763486 R 446462 CDS YP_003103399.1 256379739 8329946 complement(6764613..6765341) 1 NC_013093.1 TIGRFAM: dethiobiotin synthase; KEGG: ade:Adeh_0070 dethiobiotin synthase; dethiobiotin synthase 6765341 8329946 Amir_5739 Actinosynnema mirum DSM 43827 dethiobiotin synthase YP_003103399.1 6764613 R 446462 CDS YP_003103400.1 256379740 8329947 6765390..6765635 1 NC_013093.1 PFAM: glutaredoxin; KEGG: mno:Mnod_5953 glutaredoxin 3; glutaredoxin 6765635 8329947 Amir_5740 Actinosynnema mirum DSM 43827 glutaredoxin YP_003103400.1 6765390 D 446462 CDS YP_003103401.1 256379741 8329948 6765641..6766285 1 NC_013093.1 KEGG: MFS transporter; hypothetical protein 6766285 8329948 Amir_5741 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103401.1 6765641 D 446462 CDS YP_003103402.1 256379742 8329949 complement(6766265..6767548) 1 NC_013093.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: scl:sce0693 adenosylmethionine--8-amino-7- oxononanoate transaminase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 6767548 8329949 Amir_5742 Actinosynnema mirum DSM 43827 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_003103402.1 6766265 R 446462 CDS YP_003103403.1 256379743 8329950 complement(6768297..6771827) 1 NC_013093.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 6771827 dnaE 8329950 dnaE Actinosynnema mirum DSM 43827 DNA polymerase III subunit alpha YP_003103403.1 6768297 R 446462 CDS YP_003103404.1 256379744 8329951 6772069..6772941 1 NC_013093.1 KEGG: GA25950 gene product from transcript GA25950- RA; hypothetical protein 6772941 8329951 Amir_5744 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103404.1 6772069 D 446462 CDS YP_003103405.1 256379745 8329952 6773314..6774567 1 NC_013093.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bce:BC0204 bicyclomycin resistance protein; Bcr/CflA subfamily drug resistance transporter 6774567 8329952 Amir_5745 Actinosynnema mirum DSM 43827 Bcr/CflA subfamily drug resistance transporter YP_003103405.1 6773314 D 446462 CDS YP_003103406.1 256379746 8329953 complement(6774660..6775592) 1 NC_013093.1 KEGG: gsu:GSU0082 ribosomal large subunit pseudouridine synthase D; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; RluA family pseudouridine synthase 6775592 8329953 Amir_5746 Actinosynnema mirum DSM 43827 RluA family pseudouridine synthase YP_003103406.1 6774660 R 446462 CDS YP_003103407.1 256379747 8329954 complement(6775589..6776353) 1 NC_013093.1 TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: sde:Sde_2565 signal peptidase II; lipoprotein signal peptidase 6776353 8329954 Amir_5747 Actinosynnema mirum DSM 43827 lipoprotein signal peptidase YP_003103407.1 6775589 R 446462 CDS YP_003103408.1 256379748 8329955 complement(6776394..6777752) 1 NC_013093.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce1210 hypothetical protein; class V aminotransferase 6777752 8329955 Amir_5748 Actinosynnema mirum DSM 43827 class V aminotransferase YP_003103408.1 6776394 R 446462 CDS YP_003103409.1 256379749 8329956 complement(6778117..6779595) 1 NC_013093.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 6779595 8329956 Amir_5749 Actinosynnema mirum DSM 43827 potassium/proton antiporter YP_003103409.1 6778117 R 446462 CDS YP_003103410.1 256379750 8329958 6781173..6781736 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMa1660 hypothetical protein; GCN5-like N-acetyltransferase 6781736 8329958 Amir_5751 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103410.1 6781173 D 446462 CDS YP_003103411.1 256379751 8329959 complement(6781872..6782144) 1 NC_013093.1 PFAM: protein of unknown function DUF167; KEGG: scl:sce8156 hypothetical protein; hypothetical protein 6782144 8329959 Amir_5752 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103411.1 6781872 R 446462 CDS YP_003103412.1 256379752 8329960 complement(6782243..6785356) 1 NC_013093.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 6785356 ileS 8329960 ileS Actinosynnema mirum DSM 43827 isoleucyl-tRNA synthetase YP_003103412.1 6782243 R 446462 CDS YP_003103413.1 256379753 8329961 complement(6785621..6786352) 1 NC_013093.1 KEGG: col-102; COllagen; hypothetical protein 6786352 8329961 Amir_5754 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103413.1 6785621 R 446462 CDS YP_003103414.1 256379754 8329962 complement(6786401..6787222) 1 NC_013093.1 PFAM: DivIVA family protein; KEGG: hypothetical protein; DivIVA family protein 6787222 8329962 Amir_5755 Actinosynnema mirum DSM 43827 DivIVA family protein YP_003103414.1 6786401 R 446462 CDS YP_003103415.1 256379755 8329963 complement(6787268..6787552) 1 NC_013093.1 PFAM: protein of unknown function YGGT; hypothetical protein 6787552 8329963 Amir_5756 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103415.1 6787268 R 446462 CDS YP_003103416.1 256379756 8329964 complement(6787573..6788220) 1 NC_013093.1 PFAM: protein of unknown function DUF552; KEGG: bha:BH2549 hypothetical protein; hypothetical protein 6788220 8329964 Amir_5757 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103416.1 6787573 R 446462 CDS YP_003103417.1 256379757 8329965 complement(6788288..6788983) 1 NC_013093.1 PFAM: alanine racemase domain protein; KEGG: pag:PLES_03921 PLP dependent enzyme; alanine racemase domain-containing protein 6788983 8329965 Amir_5758 Actinosynnema mirum DSM 43827 alanine racemase domain-containing protein YP_003103417.1 6788288 R 446462 CDS YP_003103418.1 256379758 8329966 complement(6788980..6789666) 1 NC_013093.1 PFAM: protein of unknown function DUF152; KEGG: tgr:Tgr7_0816 protein of unknown function DUF152; hypothetical protein 6789666 8329966 Amir_5759 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103418.1 6788980 R 446462 CDS YP_003103419.1 256379759 8329967 complement(6789842..6791056) 1 NC_013093.1 TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ domain protein; KEGG: bat:BAS3757 cell division protein FtsZ; cell division protein FtsZ 6791056 8329967 Amir_5760 Actinosynnema mirum DSM 43827 cell division protein FtsZ YP_003103419.1 6789842 R 446462 CDS YP_003103420.1 256379760 8329968 complement(6791578..6792300) 1 NC_013093.1 PFAM: polypeptide-transport-associated domain protein FtsQ-type; cell division protein FtsQ; KEGG: ade:Adeh_3776 cell division protein FtsQ; polypeptide-transport-associated protein domain-containing protein FtsQ-type 6792300 8329968 Amir_5761 Actinosynnema mirum DSM 43827 polypeptide-transport-associated protein domain-containing protein FtsQ-type YP_003103420.1 6791578 R 446462 CDS YP_003103421.1 256379761 8329969 complement(6792297..6793697) 1 NC_013093.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 6793697 murC 8329969 murC Actinosynnema mirum DSM 43827 UDP-N-acetylmuramate--L-alanine ligase YP_003103421.1 6792297 R 446462 CDS YP_003103422.1 256379762 8329970 complement(6793694..6794764) 1 NC_013093.1 KEGG: aba:Acid345_3629 UDP-N-acetylglucosamine--N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase; TIGRFAM:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase; PFAM: glycosyltransferase 28 domain; glycosyl transferase family 28; UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase 6794764 8329970 Amir_5763 Actinosynnema mirum DSM 43827 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase YP_003103422.1 6793694 R 446462 CDS YP_003103423.1 256379763 8329971 complement(6795220..6796683) 1 NC_013093.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: bce:BC3911 stage V sporulation protein E; cell division protein FtsW 6796683 8329971 Amir_5764 Actinosynnema mirum DSM 43827 cell division protein FtsW YP_003103423.1 6795220 R 446462 CDS YP_003103424.1 256379764 8329972 complement(6796793..6798007) 1 NC_013093.1 KEGG: rec:RHECIAT_PA0000107 hypothetical protein; hypothetical protein 6798007 8329972 Amir_5765 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103424.1 6796793 R 446462 CDS YP_003103425.1 256379765 8329973 complement(6798009..6798470) 1 NC_013093.1 hypothetical protein 6798470 8329973 Amir_5766 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103425.1 6798009 R 446462 CDS YP_003103426.1 256379766 8329974 complement(6798490..6799767) 1 NC_013093.1 KEGG: sfu:Sfum_1001 FAD dependent oxidoreductase; FAD-dependent dehydrogenase-like protein 6799767 8329974 Amir_5767 Actinosynnema mirum DSM 43827 FAD-dependent dehydrogenase-like protein YP_003103426.1 6798490 R 446462 CDS YP_003103427.1 256379767 8329975 complement(6799922..6801274) 1 NC_013093.1 TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: scl:sce1662 UDP-N-acetylmuramoylalanine-D- glutamate ligase; UDP-N-acetylmuramoylalanine/D-glutamate ligase 6801274 8329975 Amir_5768 Actinosynnema mirum DSM 43827 UDP-N-acetylmuramoylalanine/D-glutamate ligase YP_003103427.1 6799922 R 446462 CDS YP_003103428.1 256379768 8329976 complement(6801277..6802365) 1 NC_013093.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 6802365 mraY 8329976 mraY Actinosynnema mirum DSM 43827 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_003103428.1 6801277 R 446462 CDS YP_003103429.1 256379769 8329977 complement(6802362..6803834) 1 NC_013093.1 TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-di aminopimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: aeh:Mlg_2197 UDP-N-acetylmuramoyl-tripeptide-- D-alanyl-D-alanine ligase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanylligase 6803834 8329977 Amir_5770 Actinosynnema mirum DSM 43827 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanylligase YP_003103429.1 6802362 R 446462 CDS YP_003103430.1 256379770 8329978 complement(6803831..6805414) 1 NC_013093.1 TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: ade:Adeh_3766 UDP-N-acetylmuramoylalanyl-D- glutamate--2,6-diaminopimelate ligase; UDP-N-acetylmuramyl-tripeptide synthetase 6805414 8329978 Amir_5771 Actinosynnema mirum DSM 43827 UDP-N-acetylmuramyl-tripeptide synthetase YP_003103430.1 6803831 R 446462 CDS YP_003103431.1 256379771 8329979 complement(6805477..6807384) 1 NC_013093.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ppd:Ppro_3295 peptidoglycan glycosyltransferase; peptidoglycan glycosyltransferase 6807384 8329979 Amir_5772 Actinosynnema mirum DSM 43827 peptidoglycan glycosyltransferase YP_003103431.1 6805477 R 446462 CDS YP_003103432.1 256379772 8329980 complement(6807922..6808683) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6808683 8329980 Amir_5773 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103432.1 6807922 R 446462 CDS YP_003103433.1 256379773 8329981 complement(6808680..6809630) 1 NC_013093.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: gbm:Gbem_0483 S-adenosyl-methyltransferase MraW; S-adenosyl-methyltransferase MraW 6809630 mraW 8329981 mraW Actinosynnema mirum DSM 43827 S-adenosyl-methyltransferase MraW YP_003103433.1 6808680 R 446462 CDS YP_003103434.1 256379774 8329982 complement(6810010..6810441) 1 NC_013093.1 TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: bha:BH2576 cell division protein MraZ; MraZ protein 6810441 8329982 Amir_5775 Actinosynnema mirum DSM 43827 MraZ protein YP_003103434.1 6810010 R 446462 CDS YP_003103435.1 256379775 8329983 6810934..6811998 1 NC_013093.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: bha:BH0604 methanol dehydrogenase regulatory protein; ATPase 6811998 8329983 Amir_5776 Actinosynnema mirum DSM 43827 ATPase YP_003103435.1 6810934 D 446462 CDS YP_003103436.1 256379776 8329984 6812000..6813289 1 NC_013093.1 PFAM: protein of unknown function DUF58; KEGG: gur:Gura_0188 hypothetical protein; hypothetical protein 6813289 8329984 Amir_5777 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103436.1 6812000 D 446462 CDS YP_003103437.1 256379777 8329985 6813290..6815737 1 NC_013093.1 PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: aba:Acid345_2146 transglutaminase-like; transglutaminase domain-containing protein 6815737 8329985 Amir_5778 Actinosynnema mirum DSM 43827 transglutaminase domain-containing protein YP_003103437.1 6813290 D 446462 CDS YP_003103438.1 256379778 8329986 complement(6816367..6816753) 1 NC_013093.1 hypothetical protein 6816753 8329986 Amir_5779 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103438.1 6816367 R 446462 CDS YP_003103439.1 256379779 8329987 complement(6817206..6818273) 1 NC_013093.1 KEGG: GF24314 gene product from transcript GF24314- RA; hypothetical protein 6818273 8329987 Amir_5780 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103439.1 6817206 R 446462 CDS YP_003103440.1 256379780 8329988 complement(6818311..6819327) 1 NC_013093.1 KEGG: similar to keratinocytes proline-rich protein; hypothetical protein 6819327 8329988 Amir_5781 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103440.1 6818311 R 446462 CDS YP_003103441.1 256379781 8329989 complement(6819539..6819802) 1 NC_013093.1 hypothetical protein 6819802 8329989 Amir_5782 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103441.1 6819539 R 446462 CDS YP_003103442.1 256379782 8329990 complement(6819882..6820520) 1 NC_013093.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; cyclic nucleotide- binding; KEGG: lch:Lcho_0755 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 6820520 8329990 Amir_5783 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003103442.1 6819882 R 446462 CDS YP_003103443.1 256379783 8329991 complement(6820903..6822195) 1 NC_013093.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: acp:A2cp1_0159 DNA-directed DNA polymerase; DNA-directed DNA polymerase 6822195 8329991 Amir_5784 Actinosynnema mirum DSM 43827 DNA-directed DNA polymerase YP_003103443.1 6820903 R 446462 CDS YP_003103444.1 256379784 8329992 complement(6822244..6823335) 1 NC_013093.1 PFAM: amidohydrolase 2; KEGG: hypothetical protein; amidohydrolase 2 6823335 8329992 Amir_5785 Actinosynnema mirum DSM 43827 amidohydrolase 2 YP_003103444.1 6822244 R 446462 CDS YP_003103445.1 256379785 8329993 6823374..6824702 1 NC_013093.1 PFAM: glutamine synthetase catalytic region; KEGG: pag:PLES_59041 glutamine synthetase; glutamine synthetase 6824702 8329993 Amir_5786 Actinosynnema mirum DSM 43827 glutamine synthetase YP_003103445.1 6823374 D 446462 CDS YP_003103446.1 256379786 8329994 complement(6824722..6825315) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpb:RPB_3555 RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 6825315 8329994 Amir_5787 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103446.1 6824722 R 446462 CDS YP_003103447.1 256379787 8329995 complement(6825326..6826057) 1 NC_013093.1 PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: ank:AnaeK_0691 methyltransferase type 11; type 12 methyltransferase 6826057 8329995 Amir_5788 Actinosynnema mirum DSM 43827 type 12 methyltransferase YP_003103447.1 6825326 R 446462 CDS YP_003103448.1 256379788 8329996 6826092..6826928 1 NC_013093.1 PFAM: cobyrinic acid ac-diamide synthase; KEGG: gox:GOX1063 chromosome partitioning protein ParA; cobyrinic acid ac-diamide synthase 6826928 8329996 Amir_5789 Actinosynnema mirum DSM 43827 cobyrinic acid ac-diamide synthase YP_003103448.1 6826092 D 446462 CDS YP_003103449.1 256379789 8329997 6826950..6827747 1 NC_013093.1 PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; KEGG: afw:Anae109_1725 DNA-(apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyase 6827747 8329997 Amir_5790 Actinosynnema mirum DSM 43827 DNA glycosylase/AP lyase YP_003103449.1 6826950 D 446462 CDS YP_003103450.1 256379790 8329998 6827758..6828786 1 NC_013093.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 6828786 8329998 Amir_5791 Actinosynnema mirum DSM 43827 dihydroorotate dehydrogenase 2 YP_003103450.1 6827758 D 446462 CDS YP_003103451.1 256379791 8329999 complement(6828793..6829443) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: rso:RS05498 transcription regulator protein; TetR family transcriptional regulator 6829443 8329999 Amir_5792 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003103451.1 6828793 R 446462 CDS YP_003103452.1 256379792 8330000 6829547..6830260 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bpy:Bphyt_6660 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6830260 8330000 Amir_5793 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003103452.1 6829547 D 446462 CDS YP_003103453.1 256379793 8330001 complement(6830296..6831543) 1 NC_013093.1 PFAM: xanthine/uracil/vitamin C permease; KEGG: bmv:BMASAVP1_A3006 uracil-xanthine permease; xanthine/uracil/vitamin C permease 6831543 8330001 Amir_5794 Actinosynnema mirum DSM 43827 xanthine/uracil/vitamin C permease YP_003103453.1 6830296 R 446462 CDS YP_003103454.1 256379794 8330002 complement(6832041..6832829) 1 NC_013093.1 KEGG: jan:Jann_1769 mucin-associated surface protein; hypothetical protein 6832829 8330002 Amir_5795 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103454.1 6832041 R 446462 CDS YP_003103455.1 256379795 8330003 complement(6832844..6833710) 1 NC_013093.1 PFAM: PspA/IM30 family protein; KEGG: GG12650 gene product from transcript GG12650- RA; phage shock protein PspA 6833710 8330003 Amir_5796 Actinosynnema mirum DSM 43827 phage shock protein PspA YP_003103455.1 6832844 R 446462 CDS YP_003103456.1 256379796 8330004 complement(6833998..6834414) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pde:Pden_1785 helix-turn-helix domain protein; helix-turn-helix domain-containing protein 6834414 8330004 Amir_5797 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003103456.1 6833998 R 446462 CDS YP_003103457.1 256379797 8330005 complement(6834580..6835191) 1 NC_013093.1 PFAM: CinA domain protein; KEGG: hypothetical protein; CinA domain-containing protein 6835191 8330005 Amir_5798 Actinosynnema mirum DSM 43827 CinA domain-containing protein YP_003103457.1 6834580 R 446462 CDS YP_003103458.1 256379798 8330006 complement(6835188..6835772) 1 NC_013093.1 TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bha:BH2386 phosphatidylglycerophosphate synthase; CDP-diacylglycerol/glycerol-3-phosphate3- phosphatidyltransferase 6835772 8330006 Amir_5799 Actinosynnema mirum DSM 43827 CDP-diacylglycerol/glycerol-3-phosphate3- phosphatidyltransferase YP_003103458.1 6835188 R 446462 CDS YP_003103459.1 256379799 8330007 complement(6835769..6837178) 1 NC_013093.1 KEGG: ank:AnaeK_0100 MiaB-like tRNA modifying enzyme YliG; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: Protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying protein YliG 6837178 8330007 Amir_5800 Actinosynnema mirum DSM 43827 MiaB-like tRNA modifying protein YliG YP_003103459.1 6835769 R 446462 CDS YP_003103460.1 256379800 8330008 6837451..6837951 1 NC_013093.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase 6837951 8330008 Amir_5801 Actinosynnema mirum DSM 43827 N-acetylglutamate synthase YP_003103460.1 6837451 D 446462 CDS YP_003103461.1 256379801 8330009 6838066..6838920 1 NC_013093.1 SMART: regulatory protein MerR; KEGG: bmn:BMA10247_A1013 MerR family transcriptional regulator; MerR family transcriptional regulator 6838920 8330009 Amir_5802 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003103461.1 6838066 D 446462 CDS YP_003103462.1 256379802 8330010 6839066..6839521 1 NC_013093.1 PFAM: Prokaryotic phospholipase A2; KEGG: hypothetical protein; phospholipase A2 6839521 8330010 Amir_5803 Actinosynnema mirum DSM 43827 phospholipase A2 YP_003103462.1 6839066 D 446462 CDS YP_003103463.1 256379803 8330011 complement(6839532..6842093) 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: bha:BH2395 hypothetical protein; cell division protein FtsK/SpoIIIE 6842093 8330011 Amir_5804 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003103463.1 6839532 R 446462 CDS YP_003103464.1 256379804 8330012 6842226..6843032 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: dde:Dde_1136 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase 6843032 8330012 Amir_5805 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003103464.1 6842226 D 446462 CDS YP_003103465.1 256379805 8330013 complement(6843154..6844833) 1 NC_013093.1 PFAM: beta-lactamase domain protein; RNA- metabolising metallo-beta-lactamase; KEGG: gme:Gmet_0366 hypothetical protein; beta-lactamase domain-containing protein 6844833 8330013 Amir_5806 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003103465.1 6843154 R 446462 CDS YP_003103466.1 256379806 8330014 complement(6844830..6845726) 1 NC_013093.1 KEGG: bha:BH2399 dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; dihydrodipicolinate synthase 6845726 8330014 Amir_5807 Actinosynnema mirum DSM 43827 dihydrodipicolinate synthase YP_003103466.1 6844830 R 446462 CDS YP_003103467.1 256379807 8330015 complement(6845764..6846384) 1 NC_013093.1 hypothetical protein 6846384 8330015 Amir_5808 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103467.1 6845764 R 446462 CDS YP_003103468.1 256379808 8330016 complement(6846455..6847918) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: sus:Acid_3693 serine/threonine protein kinase; serine/threonine protein kinase 6847918 8330016 Amir_5809 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003103468.1 6846455 R 446462 CDS YP_003103469.1 256379809 8330018 complement(6848385..6849137) 1 NC_013093.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 6849137 thyX 8330018 thyX Actinosynnema mirum DSM 43827 FAD-dependent thymidylate synthase YP_003103469.1 6848385 R 446462 CDS YP_003103470.1 256379810 8330019 6849368..6849925 1 NC_013093.1 PFAM: HicB family protein; KEGG: GI22065 gene product from transcript GI22065- RA; HicB family protein 6849925 8330019 Amir_5812 Actinosynnema mirum DSM 43827 HicB family protein YP_003103470.1 6849368 D 446462 CDS YP_003103471.1 256379811 8330020 6849947..6850840 1 NC_013093.1 KEGG: aba:Acid345_3530 hypothetical protein; hypothetical protein 6850840 8330020 Amir_5813 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103471.1 6849947 D 446462 CDS YP_003103472.1 256379812 8330021 complement(6851015..6851602) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bja:bll5689 transcriptional regulatory protein; TetR family transcriptional regulator 6851602 8330021 Amir_5814 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003103472.1 6851015 R 446462 CDS YP_003103473.1 256379813 8330023 complement(6853486..6854484) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: rlt:Rleg2_2710 aldo/keto reductase; aldo/keto reductase 6854484 8330023 Amir_5816 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003103473.1 6853486 R 446462 CDS YP_003103474.1 256379814 8330024 complement(6854561..6855781) 1 NC_013093.1 PFAM: protein of unknown function DUF1006; KEGG: pae:PA2844 hypothetical protein; hypothetical protein 6855781 8330024 Amir_5817 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103474.1 6854561 R 446462 CDS YP_003103475.1 256379815 8330025 6855837..6856403 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bac:BamMC406_4804 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 6856403 8330025 Amir_5818 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103475.1 6855837 D 446462 CDS YP_003103476.1 256379816 8330026 6856411..6856914 1 NC_013093.1 hypothetical protein 6856914 8330026 Amir_5819 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103476.1 6856411 D 446462 CDS YP_003103477.1 256379817 8330027 complement(6856993..6857445) 1 NC_013093.1 hypothetical protein 6857445 8330027 Amir_5820 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103477.1 6856993 R 446462 CDS YP_003103478.1 256379818 8330028 complement(6857442..6858149) 1 NC_013093.1 KEGG: bcz:BCZK1415 dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase 6858149 8330028 Amir_5821 Actinosynnema mirum DSM 43827 dihydrodipicolinate reductase YP_003103478.1 6857442 R 446462 CDS YP_003103479.1 256379819 8330029 complement(6858206..6859591) 1 NC_013093.1 PFAM: peptidase M16 domain protein; KEGG: gur:Gura_1907 peptidase M16 domain-containing protein; peptidase M16 domain-containing protein 6859591 8330029 Amir_5822 Actinosynnema mirum DSM 43827 peptidase M16 domain-containing protein YP_003103479.1 6858206 R 446462 CDS YP_003103480.1 256379820 8330030 complement(6859588..6861831) 1 NC_013093.1 KEGG: ilo:IL0964 polynucleotide phosphorylase/polyadenylase; TIGRFAM: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; RNA binding S1 domain protein; Exoribonuclease, phosphorolytic domain 2; KH type 1 domain protein; SMART: RNA binding S1 domain protein; KH domain protein; polynucleotide phosphorylase/polyadenylase 6861831 8330030 Amir_5823 Actinosynnema mirum DSM 43827 polynucleotide phosphorylase/polyadenylase YP_003103480.1 6859588 R 446462 CDS YP_003103481.1 256379821 8330031 complement(6862077..6862346) 1 NC_013093.1 TIGRFAM: ribosomal protein S15; PFAM: ribosomal protein S15; KEGG: gsu:GSU1592 30S ribosomal protein S15; 30S ribosomal protein S15 6862346 8330031 Amir_5824 Actinosynnema mirum DSM 43827 30S ribosomal protein S15 YP_003103481.1 6862077 R 446462 CDS YP_003103482.1 256379822 8330032 complement(6862472..6862933) 1 NC_013093.1 TIGRFAM: 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; KEGG: scl:sce5087 hypothetical protein; 2'-5' RNA ligase 6862933 8330032 Amir_5825 Actinosynnema mirum DSM 43827 2'-5' RNA ligase YP_003103482.1 6862472 R 446462 CDS YP_003103483.1 256379823 8330033 complement(6862930..6863409) 1 NC_013093.1 KEGG: oan:Oant_1395 ABC transporter; hypothetical protein 6863409 8330033 Amir_5826 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103483.1 6862930 R 446462 CDS YP_003103484.1 256379824 8330034 complement(6863510..6864442) 1 NC_013093.1 TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; riboflavin kinase; KEGG: dvm:DvMF_1762 riboflavin biosynthesis protein RibF; riboflavin biosynthesis protein RibF 6864442 8330034 Amir_5827 Actinosynnema mirum DSM 43827 riboflavin biosynthesis protein RibF YP_003103484.1 6863510 R 446462 CDS YP_003103485.1 256379825 8330035 complement(6865056..6865955) 1 NC_013093.1 TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; tRNA pseudouridine synthase II; KEGG: ade:Adeh_1105 tRNA pseudouridine synthase B; tRNA pseudouridine synthase B 6865955 8330035 Amir_5828 Actinosynnema mirum DSM 43827 tRNA pseudouridine synthase B YP_003103485.1 6865056 R 446462 CDS YP_003103486.1 256379826 8330036 complement(6866028..6867347) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_3100 major facilitator transporter; major facilitator superfamily protein 6867347 8330036 Amir_5829 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003103486.1 6866028 R 446462 CDS YP_003103487.1 256379827 8330037 complement(6867439..6868743) 1 NC_013093.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: MATE efflux family protein; MATE efflux family protein 6868743 8330037 Amir_5830 Actinosynnema mirum DSM 43827 MATE efflux family protein YP_003103487.1 6867439 R 446462 CDS YP_003103488.1 256379828 8330038 complement(6868828..6869838) 1 NC_013093.1 PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: pca:Pcar_1558 exopolyphosphatase related protein; phosphoesterase RecJ domain-containing protein 6869838 8330038 Amir_5831 Actinosynnema mirum DSM 43827 phosphoesterase RecJ domain-containing protein YP_003103488.1 6868828 R 446462 CDS YP_003103489.1 256379829 8330039 complement(6869849..6870298) 1 NC_013093.1 TIGRFAM: ribosome-binding factor A; PFAM: ribosome-binding factor A; KEGG: tcx:Tcr_1124 ribosome-binding factor A; ribosome-binding factor A 6870298 8330039 Amir_5832 Actinosynnema mirum DSM 43827 ribosome-binding factor A YP_003103489.1 6869849 R 446462 CDS YP_003103490.1 256379830 8330040 complement(6870318..6870614) 1 NC_013093.1 PFAM: protein of unknown function DUF503; KEGG: sus:Acid_5182 hypothetical protein; hypothetical protein 6870614 8330040 Amir_5833 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103490.1 6870318 R 446462 CDS YP_003103491.1 256379831 8330041 complement(6870713..6873817) 1 NC_013093.1 TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; translation initiation factor IF-2 domain protein; Ras family protein; KEGG: dvm:DvMF_2513 translation initiation factor IF-2; translation initiation factor IF-2 6873817 8330041 Amir_5834 Actinosynnema mirum DSM 43827 translation initiation factor IF-2 YP_003103491.1 6870713 R 446462 CDS YP_003103492.1 256379832 8330043 complement(6874271..6875284) 1 NC_013093.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 6875284 nusA 8330043 nusA Actinosynnema mirum DSM 43827 transcription elongation factor NusA YP_003103492.1 6874271 R 446462 CDS YP_003103493.1 256379833 8330044 complement(6875281..6875805) 1 NC_013093.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 6875805 8330044 Amir_5837 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103493.1 6875281 R 446462 CDS YP_003103494.1 256379834 8330045 6875961..6876398 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 6876398 8330045 Amir_5838 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103494.1 6875961 D 446462 CDS YP_003103495.1 256379835 8330046 6876395..6876835 1 NC_013093.1 hypothetical protein 6876835 8330046 Amir_5839 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103495.1 6876395 D 446462 CDS YP_003103496.1 256379836 8330047 complement(6877030..6877890) 1 NC_013093.1 KEGG: AGAP011399-PA; hypothetical protein 6877890 8330047 Amir_5840 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103496.1 6877030 R 446462 CDS YP_003103497.1 256379837 8330048 complement(6877985..6878986) 1 NC_013093.1 PFAM: aminotransferase class V; KEGG: acp:A2cp1_4498 aminotransferase class V; class V aminotransferase 6878986 8330048 Amir_5841 Actinosynnema mirum DSM 43827 class V aminotransferase YP_003103497.1 6877985 R 446462 CDS YP_003103498.1 256379838 8330049 complement(6879088..6879876) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3419 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6879876 8330049 Amir_5842 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003103498.1 6879088 R 446462 CDS YP_003103499.1 256379839 8330050 6879925..6880332 1 NC_013093.1 PFAM: protein of unknown function UPF0047; KEGG: rpe:RPE_0423 protein of unknown function UPF0047; hypothetical protein 6880332 8330050 Amir_5843 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103499.1 6879925 D 446462 CDS YP_003103500.1 256379840 8330051 6880457..6881545 1 NC_013093.1 KEGG: scl:sce6476 hypothetical protein; hypothetical protein 6881545 8330051 Amir_5844 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103500.1 6880457 D 446462 CDS YP_003103501.1 256379841 8330052 6881542..6882228 1 NC_013093.1 hypothetical protein 6882228 8330052 Amir_5845 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103501.1 6881542 D 446462 CDS YP_003103502.1 256379842 8330053 6882225..6882914 1 NC_013093.1 PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ade:Adeh_0672 haloacid dehalogenase-like hydrolase; Haloacid dehalogenase domain-containing protein hydrolase 6882914 8330053 Amir_5846 Actinosynnema mirum DSM 43827 Haloacid dehalogenase domain-containing protein hydrolase YP_003103502.1 6882225 D 446462 CDS YP_003103503.1 256379843 8330054 complement(6882984..6884729) 1 NC_013093.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 6884729 8330054 Amir_5847 Actinosynnema mirum DSM 43827 prolyl-tRNA synthetase YP_003103503.1 6882984 R 446462 CDS YP_003103504.1 256379844 8330055 6884926..6885279 1 NC_013093.1 KEGG: rle:RL3033 hypothetical protein; hypothetical protein 6885279 8330055 Amir_5848 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103504.1 6884926 D 446462 CDS YP_003103505.1 256379845 8330056 6885718..6886485 1 NC_013093.1 PFAM: protein of unknown function DUF328; KEGG: sun:SUN_0122 hypothetical protein; hypothetical protein 6886485 8330056 Amir_5849 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103505.1 6885718 D 446462 CDS YP_003103506.1 256379846 8330057 6886907..6887578 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: swi:Swit_2706 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 6887578 8330057 Amir_5850 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003103506.1 6886907 D 446462 CDS YP_003103507.1 256379847 8330058 6887701..6888429 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: gsu:GSU1992 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 6888429 8330058 Amir_5851 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003103507.1 6887701 D 446462 CDS YP_003103508.1 256379848 8330059 6888887..6890050 1 NC_013093.1 PFAM: protein of unknown function RIO1; SMART: protein of unknown function RIO1; KEGG: afw:Anae109_3105 protein of unknown function RIO1; hypothetical protein 6890050 8330059 Amir_5852 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103508.1 6888887 D 446462 CDS YP_003103509.1 256379849 8330060 6890931..6892436 1 NC_013093.1 PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: smt:Smal_0480 DEAD/DEAH box helicase domain protein; DEAD/DEAH box helicase domain-containing protein 6892436 8330060 Amir_5853 Actinosynnema mirum DSM 43827 DEAD/DEAH box helicase domain-containing protein YP_003103509.1 6890931 D 446462 CDS YP_003103510.1 256379850 8330061 complement(6892754..6893971) 1 NC_013093.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cvi:CV_0813 uroporphyrin-III C- methyltransferase; uroporphyrin-III C-methyltransferase 6893971 8330061 Amir_5854 Actinosynnema mirum DSM 43827 uroporphyrin-III C-methyltransferase YP_003103510.1 6892754 R 446462 CDS YP_003103511.1 256379851 8330062 complement(6894286..6895071) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: similar to trypsin-like proteinase; peptidase S1 and S6 chymotrypsin/Hap 6895071 8330062 Amir_5855 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003103511.1 6894286 R 446462 CDS YP_003103512.1 256379852 8330063 complement(6895160..6896419) 1 NC_013093.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: mag:amb0298 precorrin-3B methylase; cobalamin (vitamin B12) biosynthesis CbiG protein 6896419 8330063 Amir_5856 Actinosynnema mirum DSM 43827 cobalamin (vitamin B12) biosynthesis CbiG protein YP_003103512.1 6895160 R 446462 CDS YP_003103513.1 256379853 8330065 complement(6897607..6898740) 1 NC_013093.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ppd:Ppro_3231 precorrin-4 C11- methyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase 6898740 8330065 Amir_5858 Actinosynnema mirum DSM 43827 uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_003103513.1 6897607 R 446462 CDS YP_003103514.1 256379854 8330066 complement(6898911..6900308) 1 NC_013093.1 TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: gsu:GSU3006 cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 6900308 8330066 Amir_5859 Actinosynnema mirum DSM 43827 cobyrinic acid a,c-diamide synthase YP_003103514.1 6898911 R 446462 CDS YP_003103515.1 256379855 8330067 complement(6900305..6900919) 1 NC_013093.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 6900919 8330067 Amir_5860 Actinosynnema mirum DSM 43827 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_003103515.1 6900305 R 446462 CDS YP_003103516.1 256379856 8330068 complement(6901019..6903061) 1 NC_013093.1 KEGG: rso:RS03742 chelatase protein; PFAM: von Willebrand factor type A; magnesium chelatase ChlI subunit; SMART: von Willebrand factor type A; ATPase AAA; magnesium chelatase 6903061 8330068 Amir_5861 Actinosynnema mirum DSM 43827 magnesium chelatase YP_003103516.1 6901019 R 446462 CDS YP_003103517.1 256379857 8330069 complement(6903317..6904210) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bid:Bind_0032 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6904210 8330069 Amir_5862 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003103517.1 6903317 R 446462 CDS YP_003103518.1 256379858 8330070 6904272..6904940 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce4851 TetR family transcriptional regulator; TetR family transcriptional regulator 6904940 8330070 Amir_5863 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003103518.1 6904272 D 446462 CDS YP_003103519.1 256379859 8330071 6905017..6906195 1 NC_013093.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 6906195 8330071 Amir_5864 Actinosynnema mirum DSM 43827 8-amino-7-oxononanoate synthase YP_003103519.1 6905017 D 446462 CDS YP_003103520.1 256379860 8330072 complement(6906146..6906598) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pap:PSPA7_0190 hypothetical protein; GCN5-like N-acetyltransferase 6906598 8330072 Amir_5865 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103520.1 6906146 R 446462 CDS YP_003103521.1 256379861 8330073 complement(6906696..6907445) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: similar to oviductin; peptidase S1 and S6 chymotrypsin/Hap 6907445 8330073 Amir_5866 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003103521.1 6906696 R 446462 CDS YP_003103522.1 256379862 8330074 6907613..6908227 1 NC_013093.1 PFAM: lysine exporter protein (LYSE/YGGA); KEGG: cak:Caul_0349 lysine exporter protein LysE/YggA; lysine exporter protein LysE/YggA 6908227 8330074 Amir_5867 Actinosynnema mirum DSM 43827 lysine exporter protein LysE/YggA YP_003103522.1 6907613 D 446462 CDS YP_003103523.1 256379863 8330075 complement(6908247..6908978) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: similar to trypsin-like proteinase; peptidase S1 and S6 chymotrypsin/Hap 6908978 8330075 Amir_5868 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003103523.1 6908247 R 446462 CDS YP_003103524.1 256379864 8330076 complement(6909074..6909817) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: GK19455 gene product from transcript GK19455- RA; peptidase S1 and S6 chymotrypsin/Hap 6909817 8330076 Amir_5869 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003103524.1 6909074 R 446462 CDS YP_003103525.1 256379865 8330077 complement(6909986..6911020) 1 NC_013093.1 PFAM: peptidase M48 Ste24p; KEGG: hypothetical protein; peptidase M48 Ste24p 6911020 8330077 Amir_5870 Actinosynnema mirum DSM 43827 peptidase M48 Ste24p YP_003103525.1 6909986 R 446462 CDS YP_003103526.1 256379866 8330078 6911101..6912030 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: abb:ABBFA_001367 alpha/beta hydrolase fold family protein; alpha/beta hydrolase fold protein 6912030 8330078 Amir_5871 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003103526.1 6911101 D 446462 CDS YP_003103527.1 256379867 8330079 6912027..6912692 1 NC_013093.1 KEGG: tgr:Tgr7_3169 streptogramin A acetyl transferase; streptogramin A acetyl transferase 6912692 8330079 Amir_5872 Actinosynnema mirum DSM 43827 streptogramin A acetyl transferase YP_003103527.1 6912027 D 446462 CDS YP_003103528.1 256379868 8330080 complement(6912767..6915124) 1 NC_013093.1 KEGG: scl:sce5003 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: ATPase AAA; peptidase S16 lon domain protein; ATPase associated with various cellular activities AAA_5; SMART: peptidase S16 lon domain protein; ATPase AAA; ATP-dependent protease La 6915124 8330080 Amir_5873 Actinosynnema mirum DSM 43827 ATP-dependent protease La YP_003103528.1 6912767 R 446462 CDS YP_003103529.1 256379869 8330081 6915296..6916096 1 NC_013093.1 PFAM: protein of unknown function DUF574; KEGG: scl:sce6070 hypothetical protein; hypothetical protein 6916096 8330081 Amir_5874 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103529.1 6915296 D 446462 CDS YP_003103530.1 256379870 8330082 complement(6916175..6918115) 1 NC_013093.1 PFAM: Patatin; KEGG: acp:A2cp1_0560 thermosensitive mutation transmembrane protein, SuhR; patatin 6918115 8330082 Amir_5875 Actinosynnema mirum DSM 43827 patatin YP_003103530.1 6916175 R 446462 CDS YP_003103531.1 256379871 8330083 complement(6918272..6919069) 1 NC_013093.1 PFAM: polysaccharide deacetylase; KEGG: aba:Acid345_4749 polysaccharide deacetylase; polysaccharide deacetylase 6919069 8330083 Amir_5876 Actinosynnema mirum DSM 43827 polysaccharide deacetylase YP_003103531.1 6918272 R 446462 CDS YP_003103532.1 256379872 8330084 6919203..6919730 1 NC_013093.1 PFAM: PEBP family protein; KEGG: eta:ETA_22690 hypothetical protein; PEBP family protein 6919730 8330084 Amir_5877 Actinosynnema mirum DSM 43827 PEBP family protein YP_003103532.1 6919203 D 446462 CDS YP_003103533.1 256379873 8330085 6919772..6921154 1 NC_013093.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; mycothione reductase 6921154 8330085 Amir_5878 Actinosynnema mirum DSM 43827 mycothione reductase YP_003103533.1 6919772 D 446462 CDS YP_003103534.1 256379874 8330086 complement(6921251..6922588) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: rpi:Rpic_4548 major facilitator superfamily MFS_1; major facilitator superfamily protein 6922588 8330086 Amir_5879 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003103534.1 6921251 R 446462 CDS YP_003103535.1 256379875 8330087 6922672..6923343 1 NC_013093.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: psa:PST_2058 probable transcriptional regulator; GntR family transcriptional regulator 6923343 8330087 Amir_5880 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003103535.1 6922672 D 446462 CDS YP_003103536.1 256379876 8330088 complement(6923525..6924439) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rlt:Rleg2_1625 transcriptional regulator, LysR family; LysR family transcriptional regulator 6924439 8330088 Amir_5881 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003103536.1 6923525 R 446462 CDS YP_003103537.1 256379877 8330089 6924514..6925413 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pae:PA4779 hypothetical protein; hypothetical protein 6925413 8330089 Amir_5882 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103537.1 6924514 D 446462 CDS YP_003103538.1 256379878 8330090 complement(6925421..6926950) 1 NC_013093.1 TIGRFAM: cobyric acid synthase CobQ; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SNO glutamine amidotransferase; cobyrinic acid ac-diamide synthase; KEGG: aeh:Mlg_2812 adenosylcobyric acid synthase (glutamine-hydrolysing); cobyric acid synthase CobQ 6926950 8330090 Amir_5883 Actinosynnema mirum DSM 43827 cobyric acid synthase CobQ YP_003103538.1 6925421 R 446462 CDS YP_003103539.1 256379879 8330091 6926997..6927704 1 NC_013093.1 KEGG: bbt:BBta_2719 hypothetical protein; hypothetical protein 6927704 8330091 Amir_5884 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103539.1 6926997 D 446462 CDS YP_003103540.1 256379880 8330092 complement(6927726..6928583) 1 NC_013093.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: afw:Anae109_2425 methionine aminopeptidase; methionine aminopeptidase, type I 6928583 8330092 Amir_5885 Actinosynnema mirum DSM 43827 methionine aminopeptidase, type I YP_003103540.1 6927726 R 446462 CDS YP_003103541.1 256379881 8330093 complement(6928643..6930442) 1 NC_013093.1 PFAM: penicillin-binding protein transpeptidase; NTF2 domain protein transpeptidase; KEGG: mxa:MXAN_7139 penicillin-binding protein; penicillin-binding protein transpeptidase 6930442 8330093 Amir_5886 Actinosynnema mirum DSM 43827 penicillin-binding protein transpeptidase YP_003103541.1 6928643 R 446462 CDS YP_003103542.1 256379882 8330094 complement(6930460..6931314) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_1267 hypothetical protein; GCN5-like N-acetyltransferase 6931314 8330094 Amir_5887 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103542.1 6930460 R 446462 CDS YP_003103543.1 256379883 8330095 complement(6931365..6932522) 1 NC_013093.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 6932522 ispG 8330095 ispG Actinosynnema mirum DSM 43827 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_003103543.1 6931365 R 446462 CDS YP_003103544.1 256379884 8330096 complement(6932550..6933761) 1 NC_013093.1 PFAM: peptidase M50; KEGG: gbm:Gbem_2749 membrane-associated zinc metalloprotease; peptidase M50 6933761 8330096 Amir_5889 Actinosynnema mirum DSM 43827 peptidase M50 YP_003103544.1 6932550 R 446462 CDS YP_003103545.1 256379885 8330097 complement(6933764..6934984) 1 NC_013093.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6934984 8330097 Amir_5890 Actinosynnema mirum DSM 43827 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_003103545.1 6933764 R 446462 CDS YP_003103546.1 256379886 8330098 6935143..6935409 1 NC_013093.1 PFAM: transglycosylase-associated protein; KEGG: csa:Csal_2587 transglycosylase-associated protein; transglycosylase-associated protein 6935409 8330098 Amir_5891 Actinosynnema mirum DSM 43827 transglycosylase-associated protein YP_003103546.1 6935143 D 446462 CDS YP_003103547.1 256379887 8330099 complement(6935607..6936353) 1 NC_013093.1 hypothetical protein 6936353 8330099 Amir_5892 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103547.1 6935607 R 446462 CDS YP_003103548.1 256379888 8330100 complement(6936367..6937023) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 6937023 8330100 Amir_5893 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003103548.1 6936367 R 446462 CDS YP_003103549.1 256379889 8330101 complement(6937027..6938694) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: xcb:XC_0113 two-component system sensor protein; histidine kinase 6938694 8330101 Amir_5894 Actinosynnema mirum DSM 43827 histidine kinase YP_003103549.1 6937027 R 446462 CDS YP_003103550.1 256379890 8330102 complement(6938735..6939562) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: met:M446_6381 ornithine carbamoyltransferase; ornithine carbamoyltransferase 6939562 8330102 Amir_5895 Actinosynnema mirum DSM 43827 ornithine carbamoyltransferase YP_003103550.1 6938735 R 446462 CDS YP_003103551.1 256379891 8330103 complement(6939559..6940407) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sus:Acid_2368 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 6940407 8330103 Amir_5896 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003103551.1 6939559 R 446462 CDS YP_003103552.1 256379892 8330104 complement(6940407..6941558) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 1; KEGG: cak:Caul_3951 extracellular solute-binding protein; family 1 extracellular solute-binding protein 6941558 8330104 Amir_5897 Actinosynnema mirum DSM 43827 family 1 extracellular solute-binding protein YP_003103552.1 6940407 R 446462 CDS YP_003103553.1 256379893 8330105 complement(6941551..6942666) 1 NC_013093.1 KEGG: pap:PSPA7_1534 polyamine transport protein PotA; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter; TOBE domain protein; transport-associated OB domain protein; SMART: ATPase AAA; spermidine/putrescine ABC transporter ATPase subunit 6942666 8330105 Amir_5898 Actinosynnema mirum DSM 43827 spermidine/putrescine ABC transporter ATPase subunit YP_003103553.1 6941551 R 446462 CDS YP_003103554.1 256379894 8330106 6942913..6943170 1 NC_013093.1 hypothetical protein 6943170 8330106 Amir_5899 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103554.1 6942913 D 446462 CDS YP_003103555.1 256379895 8330107 complement(6943325..6944755) 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: afw:Anae109_0235 protein kinase; serine/threonine protein kinase 6944755 8330107 Amir_5900 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003103555.1 6943325 R 446462 CDS YP_003103556.1 256379896 8330108 6944835..6945323 1 NC_013093.1 hypothetical protein 6945323 8330108 Amir_5901 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103556.1 6944835 D 446462 CDS YP_003103557.1 256379897 8330109 complement(6945530..6946636) 1 NC_013093.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 6946636 8330109 Amir_5902 Actinosynnema mirum DSM 43827 ribosomal RNA large subunit methyltransferase N YP_003103557.1 6945530 R 446462 CDS YP_003103558.1 256379898 8330110 6946747..6947697 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: scl:sce3089 PadR family transcriptional regulator; PadR family transcriptional regulator 6947697 8330110 Amir_5903 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003103558.1 6946747 D 446462 CDS YP_003103559.1 256379899 8330111 complement(6947769..6948722) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: rlt:Rleg2_1253 aldo/keto reductase; aldo/keto reductase 6948722 8330111 Amir_5904 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003103559.1 6947769 R 446462 CDS YP_003103560.1 256379900 8330112 complement(6948757..6949494) 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: acp:A2cp1_3874 methyltransferase type 11; type 11 methyltransferase 6949494 8330112 Amir_5905 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003103560.1 6948757 R 446462 CDS YP_003103561.1 256379901 8330113 6949556..6950371 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sse:Ssed_0208 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 6950371 8330113 Amir_5906 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003103561.1 6949556 D 446462 CDS YP_003103562.1 256379902 8330114 complement(6950442..6951287) 1 NC_013093.1 PFAM: phosphatidate cytidylyltransferase; KEGG: mgm:Mmc1_1845 phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase 6951287 8330114 Amir_5907 Actinosynnema mirum DSM 43827 phosphatidate cytidylyltransferase YP_003103562.1 6950442 R 446462 CDS YP_003103563.1 256379903 8330115 complement(6951375..6951932) 1 NC_013093.1 TIGRFAM: ribosome recycling factor; PFAM: ribosome recycling factor; KEGG: bha:BH2424 ribosome recycling factor; ribosome recycling factor 6951932 8330115 Amir_5908 Actinosynnema mirum DSM 43827 ribosome recycling factor YP_003103563.1 6951375 R 446462 CDS YP_003103564.1 256379904 8330116 complement(6951978..6952769) 1 NC_013093.1 TIGRFAM: uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: gme:Gmet_1252 uridylate kinase; uridylate kinase 6952769 8330116 Amir_5909 Actinosynnema mirum DSM 43827 uridylate kinase YP_003103564.1 6951978 R 446462 CDS YP_003103565.1 256379905 8330117 complement(6952852..6953667) 1 NC_013093.1 TIGRFAM: translation elongation factor Ts; PFAM: translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; KEGG: bmv:BMASAVP1_A2055 elongation factor Ts; translation elongation factor Ts 6953667 8330117 Amir_5910 Actinosynnema mirum DSM 43827 translation elongation factor Ts YP_003103565.1 6952852 R 446462 CDS YP_003103566.1 256379906 8330118 complement(6953749..6954663) 1 NC_013093.1 TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: bha:BH2427 30S ribosomal protein S2; 30S ribosomal protein S2 6954663 8330118 Amir_5911 Actinosynnema mirum DSM 43827 30S ribosomal protein S2 YP_003103566.1 6953749 R 446462 CDS YP_003103567.1 256379907 8330119 6955003..6955998 1 NC_013093.1 PFAM: peptidase M23; KEGG: fibrocystin-L-like protein; peptidase M23 6955998 8330119 Amir_5912 Actinosynnema mirum DSM 43827 peptidase M23 YP_003103567.1 6955003 D 446462 CDS YP_003103568.1 256379908 8330120 complement(6956439..6957257) 1 NC_013093.1 KEGG: mgm:Mmc1_3037 RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 3 domain protein; sigma- 70 region 4 domain protein; RNA polymerase sigma-28 subunit FliA/WhiG 6957257 8330120 Amir_5913 Actinosynnema mirum DSM 43827 RNA polymerase sigma-28 subunit FliA/WhiG YP_003103568.1 6956439 R 446462 CDS YP_003103569.1 256379909 8330121 complement(6958093..6959070) 1 NC_013093.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: afw:Anae109_2689 tyrosine recombinase XerC; integrase family protein 6959070 8330121 Amir_5914 Actinosynnema mirum DSM 43827 integrase family protein YP_003103569.1 6958093 R 446462 CDS YP_003103570.1 256379910 8330123 complement(6960896..6962416) 1 NC_013093.1 KEGG: ank:AnaeK_3688 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; Mg chelatase, subunit ChlI 6962416 8330123 Amir_5916 Actinosynnema mirum DSM 43827 Mg chelatase, subunit ChlI YP_003103570.1 6960896 R 446462 CDS YP_003103571.1 256379911 8330124 complement(6962416..6962769) 1 NC_013093.1 PFAM: protein of unknown function UPF0102; KEGG: dps:DP2807 hypothetical protein; hypothetical protein 6962769 8330124 Amir_5917 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103571.1 6962416 R 446462 CDS YP_003103572.1 256379912 8330125 complement(6963062..6963385) 1 NC_013093.1 hypothetical protein 6963385 8330125 Amir_5918 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103572.1 6963062 R 446462 CDS YP_003103573.1 256379913 8330126 complement(6963405..6964181) 1 NC_013093.1 PFAM: ribonuclease HII/HIII; KEGG: ribonuclease H; ribonuclease H 6964181 8330126 Amir_5919 Actinosynnema mirum DSM 43827 ribonuclease H YP_003103573.1 6963405 R 446462 CDS YP_003103574.1 256379914 8330127 complement(6964191..6965090) 1 NC_013093.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: TPP1; chloroplast thylakoid processing peptidase; K03100 signal peptidase I; signal peptidase I 6965090 8330127 Amir_5920 Actinosynnema mirum DSM 43827 signal peptidase I YP_003103574.1 6964191 R 446462 CDS YP_003103575.1 256379915 8330128 complement(6965095..6965961) 1 NC_013093.1 KEGG: signal peptidase, ; K03100 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; signal peptidase I 6965961 8330128 Amir_5921 Actinosynnema mirum DSM 43827 signal peptidase I YP_003103575.1 6965095 R 446462 CDS YP_003103576.1 256379916 8330129 complement(6966071..6966430) 1 NC_013093.1 TIGRFAM: ribosomal protein L19; PFAM: ribosomal protein L19; KEGG: bha:BH2478 50S ribosomal protein L19; 50S ribosomal protein L19 6966430 8330129 Amir_5922 Actinosynnema mirum DSM 43827 50S ribosomal protein L19 YP_003103576.1 6966071 R 446462 CDS YP_003103577.1 256379917 8330130 complement(6966602..6967342) 1 NC_013093.1 KEGG: glo:Glov_2453 tRNA (guanine-N1)- methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; tRNA (guanine-N1)-methyltransferase 6967342 8330130 Amir_5923 Actinosynnema mirum DSM 43827 tRNA (guanine-N1)-methyltransferase YP_003103577.1 6966602 R 446462 CDS YP_003103578.1 256379918 8330131 complement(6967332..6967850) 1 NC_013093.1 TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; KEGG: dds:Ddes_1801 16S rRNA processing protein RimM; 16S rRNA processing protein RimM 6967850 8330131 Amir_5924 Actinosynnema mirum DSM 43827 16S rRNA processing protein RimM YP_003103578.1 6967332 R 446462 CDS YP_003103579.1 256379919 8330132 complement(6967857..6968096) 1 NC_013093.1 KEGG: bha:BH2482 hypothetical protein; hypothetical protein 6968096 8330132 Amir_5925 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103579.1 6967857 R 446462 CDS YP_003103580.1 256379920 8330133 complement(6968093..6968530) 1 NC_013093.1 TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; KEGG: swi:Swit_2657 30S ribosomal protein S16; 30S ribosomal protein S16 6968530 8330133 Amir_5926 Actinosynnema mirum DSM 43827 30S ribosomal protein S16 YP_003103580.1 6968093 R 446462 CDS YP_003103581.1 256379921 8330134 complement(6968684..6969442) 1 NC_013093.1 PFAM: LamB/YcsF family protein; KEGG: pst:PSPTO_5378 hypothetical protein; LamB/YcsF family protein 6969442 8330134 Amir_5927 Actinosynnema mirum DSM 43827 LamB/YcsF family protein YP_003103581.1 6968684 R 446462 CDS YP_003103582.1 256379922 8330135 complement(6969439..6970155) 1 NC_013093.1 PFAM: abortive infection protein; KEGG: pcr:Pcryo_0794 abortive infection protein; abortive infection protein 6970155 8330135 Amir_5928 Actinosynnema mirum DSM 43827 abortive infection protein YP_003103582.1 6969439 R 446462 CDS YP_003103583.1 256379923 8330136 complement(6970955..6972025) 1 NC_013093.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: pzu:PHZ_c3063 Xaa-Pro dipeptidase; amidohydrolase 6972025 8330136 Amir_5929 Actinosynnema mirum DSM 43827 amidohydrolase YP_003103583.1 6970955 R 446462 CDS YP_003103584.1 256379924 8330137 complement(6972022..6973578) 1 NC_013093.1 KEGG: dds:Ddes_1804 signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; signal recognition particle protein 6973578 8330137 Amir_5930 Actinosynnema mirum DSM 43827 signal recognition particle protein YP_003103584.1 6972022 R 446462 CDS YP_003103585.1 256379925 8330138 complement(6973895..6974443) 1 NC_013093.1 KEGG: mlo:mll6593 hypothetical protein; hypothetical protein 6974443 8330138 Amir_5931 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103585.1 6973895 R 446462 CDS YP_003103586.1 256379926 8330139 complement(6974903..6977266) 1 NC_013093.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK; PII uridylyl-transferase 6977266 8330139 Amir_5932 Actinosynnema mirum DSM 43827 PII uridylyl-transferase YP_003103586.1 6974903 R 446462 CDS YP_003103587.1 256379927 8330140 complement(6977287..6977625) 1 NC_013093.1 PFAM: nitrogen regulatory protein P-II; KEGG: cja:CJA_3390 nitrogen regulatory protein P-II; nitrogen regulatory protein P-II 6977625 8330140 Amir_5933 Actinosynnema mirum DSM 43827 nitrogen regulatory protein P-II YP_003103587.1 6977287 R 446462 CDS YP_003103588.1 256379928 8330141 complement(6977622..6978965) 1 NC_013093.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: pca:Pcar_2589 ammonium transporter; ammonium transporter 6978965 8330141 Amir_5934 Actinosynnema mirum DSM 43827 ammonium transporter YP_003103588.1 6977622 R 446462 CDS YP_003103589.1 256379929 8330142 complement(6979450..6981006) 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: hypothetical protein; TAP domain-containing protein 6981006 8330142 Amir_5935 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003103589.1 6979450 R 446462 CDS YP_003103590.1 256379930 8330143 complement(6981139..6982134) 1 NC_013093.1 catalyzes the formation of S-ureidoglycolate and urea from allantoate; allantoicase 6982134 8330143 Amir_5936 Actinosynnema mirum DSM 43827 allantoicase YP_003103590.1 6981139 R 446462 CDS YP_003103591.1 256379931 8330144 complement(6982131..6983840) 1 NC_013093.1 KEGG: scl:sce5876 allantoinase; TIGRFAM: allantoinase; PFAM: amidohydrolase; Amidohydrolase 3; allantoinase 6983840 8330144 Amir_5937 Actinosynnema mirum DSM 43827 allantoinase YP_003103591.1 6982131 R 446462 CDS YP_003103592.1 256379932 8330145 6984153..6984647 1 NC_013093.1 TIGRFAM: OHCU decarboxylase; KEGG: spe:Spro_0938 urate oxidase, N- terminal; OHCU decarboxylase 6984647 8330145 Amir_5938 Actinosynnema mirum DSM 43827 OHCU decarboxylase YP_003103592.1 6984153 D 446462 CDS YP_003103593.1 256379933 8330146 6984682..6985563 1 NC_013093.1 KEGG: scl:sce4023 uricase; TIGRFAM: urate oxidase; PFAM: Uricase; urate oxidase 6985563 8330146 Amir_5939 Actinosynnema mirum DSM 43827 urate oxidase YP_003103593.1 6984682 D 446462 CDS YP_003103594.1 256379934 8330147 complement(6985594..6986049) 1 NC_013093.1 hypothetical protein 6986049 8330147 Amir_5940 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103594.1 6985594 R 446462 CDS YP_003103595.1 256379935 8330148 complement(6986140..6987345) 1 NC_013093.1 KEGG: scl:sce5882 hypothetical protein; hypothetical protein 6987345 8330148 Amir_5941 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103595.1 6986140 R 446462 CDS YP_003103596.1 256379936 8330149 complement(6987347..6988888) 1 NC_013093.1 KEGG: mxa:MXAN_6441 malate synthase; TIGRFAM: malate synthase A; PFAM: malate synthase; malate synthase A 6988888 8330149 Amir_5942 Actinosynnema mirum DSM 43827 malate synthase A YP_003103596.1 6987347 R 446462 CDS YP_003103597.1 256379937 8330150 6988978..6989751 1 NC_013093.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: bid:Bind_3440 IclR family transcriptional regulator; IclR family transcriptional regulator 6989751 8330150 Amir_5943 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003103597.1 6988978 D 446462 CDS YP_003103598.1 256379938 8330151 6989795..6990187 1 NC_013093.1 hypothetical protein 6990187 8330151 Amir_5944 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103598.1 6989795 D 446462 CDS YP_003103599.1 256379939 8330152 complement(6990300..6991772) 1 NC_013093.1 KEGG: pmy:Pmen_4175 signal recognition particle- docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; signal recognition particle-docking protein FtsY 6991772 8330152 Amir_5945 Actinosynnema mirum DSM 43827 signal recognition particle-docking protein FtsY YP_003103599.1 6990300 R 446462 CDS YP_003103600.1 256379940 8330153 6991893..6993017 1 NC_013093.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 6993017 anmK 8330153 anmK Actinosynnema mirum DSM 43827 anhydro-N-acetylmuramic acid kinase YP_003103600.1 6991893 D 446462 CDS YP_003103601.1 256379941 8330154 6993004..6994533 1 NC_013093.1 PFAM: Na+/solute symporter; KEGG: gdi:GDI1156 sodium cotransporter; Na+/solute symporter 6994533 8330154 Amir_5947 Actinosynnema mirum DSM 43827 Na+/solute symporter YP_003103601.1 6993004 D 446462 CDS YP_003103602.1 256379942 8330155 complement(6994874..6995812) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pzu:PHZ_c1335 L-2,4-diaminobutyric acid acetyltransferase; GCN5-like N-acetyltransferase 6995812 8330155 Amir_5948 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103602.1 6994874 R 446462 CDS YP_003103603.1 256379943 8330156 6995854..6996486 1 NC_013093.1 hypothetical protein 6996486 8330156 Amir_5949 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103603.1 6995854 D 446462 CDS YP_003103604.1 256379944 8330157 6996509..6996859 1 NC_013093.1 hypothetical protein 6996859 8330157 Amir_5950 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103604.1 6996509 D 446462 CDS YP_003103605.1 256379945 8330158 6996950..6997684 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: gur:Gura_4298 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 6997684 8330158 Amir_5951 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003103605.1 6996950 D 446462 CDS YP_003103606.1 256379946 8330159 complement(6997724..7001308) 1 NC_013093.1 TIGRFAM: chromosome segregation protein SMC; PFAM: hypothetical protein; SMCs flexible hinge domain protein; KEGG: bha:BH2487 chromosome segregation SMC protein; chromosome segregation protein SMC 7001308 8330159 Amir_5952 Actinosynnema mirum DSM 43827 chromosome segregation protein SMC YP_003103606.1 6997724 R 446462 CDS YP_003103607.1 256379947 8330160 complement(7001349..7002161) 1 NC_013093.1 KEGG: bps:BPSL1109 hypothetical protein; transmembrane anti-sigma factor 7002161 8330160 Amir_5953 Actinosynnema mirum DSM 43827 transmembrane anti-sigma factor YP_003103607.1 7001349 R 446462 CDS YP_003103608.1 256379948 8330161 complement(7002161..7002649) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: rpb:RPB_3549 RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 7002649 8330161 Amir_5954 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103608.1 7002161 R 446462 CDS YP_003103609.1 256379949 8330162 complement(7002683..7002970) 1 NC_013093.1 PFAM: acylphosphatase; KEGG: met:M446_0372 acylphosphatase; acylphosphatase 7002970 8330162 Amir_5955 Actinosynnema mirum DSM 43827 acylphosphatase YP_003103609.1 7002683 R 446462 CDS YP_003103610.1 256379950 8330163 7002996..7003676 1 NC_013093.1 PFAM: SCP-like extracellular; KEGG: bcy:Bcer98_1016 hypothetical protein; SCP-like extracellular 7003676 8330163 Amir_5956 Actinosynnema mirum DSM 43827 SCP-like extracellular YP_003103610.1 7002996 D 446462 CDS YP_003103611.1 256379951 8330164 complement(7003708..7004235) 1 NC_013093.1 hypothetical protein 7004235 8330164 Amir_5957 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103611.1 7003708 R 446462 CDS YP_003103612.1 256379952 8330165 7004406..7004897 1 NC_013093.1 KEGG: hypothetical protein LOC763622; hypothetical protein 7004897 8330165 Amir_5958 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103612.1 7004406 D 446462 CDS YP_003103613.1 256379953 8330166 7005414..7006535 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bja:blr2205 dehydrogenase; FAD dependent oxidoreductase 7006535 8330166 Amir_5959 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003103613.1 7005414 D 446462 CDS YP_003103614.1 256379954 8330167 complement(7006648..7007328) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: set:SEN0666 KDP operon transcriptional regulatory protein; winged helix family two component transcriptional regulator 7007328 8330167 Amir_5960 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003103614.1 7006648 R 446462 CDS YP_003103615.1 256379955 8330168 7007648..7008076 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bmj:BMULJ_04432 MarR family transcriptional regulator; MarR family transcriptional regulator 7008076 8330168 Amir_5961 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003103615.1 7007648 D 446462 CDS YP_003103616.1 256379956 8330169 complement(7008410..7009285) 1 NC_013093.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 7009285 8330169 Amir_5962 Actinosynnema mirum DSM 43827 formamidopyrimidine-DNA glycosylase YP_003103616.1 7008410 R 446462 CDS YP_003103617.1 256379957 8330170 complement(7009295..7009546) 1 NC_013093.1 hypothetical protein 7009546 8330170 Amir_5963 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103617.1 7009295 R 446462 CDS YP_003103618.1 256379958 8330171 complement(7009554..7010357) 1 NC_013093.1 KEGG: sat:SYN_00796 ribonuclease III; TIGRFAM: ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; SMART: ribonuclease III; double-stranded RNA binding domain protein; ribonuclease III 7010357 8330171 Amir_5964 Actinosynnema mirum DSM 43827 ribonuclease III YP_003103618.1 7009554 R 446462 CDS YP_003103619.1 256379959 8330172 complement(7010385..7010567) 1 NC_013093.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 7010567 rpmF 8330172 rpmF Actinosynnema mirum DSM 43827 50S ribosomal protein L32 YP_003103619.1 7010385 R 446462 CDS YP_003103620.1 256379960 8330173 complement(7010570..7011016) 1 NC_013093.1 PFAM: protein of unknown function DUF177; KEGG: afw:Anae109_2742 hypothetical protein; hypothetical protein 7011016 8330173 Amir_5966 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103620.1 7010570 R 446462 CDS YP_003103621.1 256379961 8330174 complement(7011277..7011993) 1 NC_013093.1 KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; cell division initiation protein 7011993 8330174 Amir_5967 Actinosynnema mirum DSM 43827 cell division initiation protein YP_003103621.1 7011277 R 446462 CDS YP_003103622.1 256379962 8330175 complement(7012129..7012611) 1 NC_013093.1 KEGG: bha:BH2589 lipopolysaccharide core biosynthesis; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; pantetheine-phosphate adenylyltransferase 7012611 8330175 Amir_5968 Actinosynnema mirum DSM 43827 pantetheine-phosphate adenylyltransferase YP_003103622.1 7012129 R 446462 CDS YP_003103623.1 256379963 8330176 complement(7012664..7013230) 1 NC_013093.1 TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase KEGG: scl:sce8059 methylase; methyltransferase 7013230 8330176 Amir_5969 Actinosynnema mirum DSM 43827 methyltransferase YP_003103623.1 7012664 R 446462 CDS YP_003103624.1 256379964 8330177 complement(7013306..7014388) 1 NC_013093.1 KEGG: mxa:MXAN_6257 hypothetical protein; hypothetical protein 7014388 8330177 Amir_5970 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103624.1 7013306 R 446462 CDS YP_003103625.1 256379965 8330178 complement(7014450..7014893) 1 NC_013093.1 hypothetical protein 7014893 8330178 Amir_5971 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103625.1 7014450 R 446462 CDS YP_003103626.1 256379966 8330179 complement(7014878..7015225) 1 NC_013093.1 hypothetical protein 7015225 8330179 Amir_5972 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103626.1 7014878 R 446462 CDS YP_003103627.1 256379967 8330180 complement(7015428..7018805) 1 NC_013093.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 7018805 8330180 Amir_5973 Actinosynnema mirum DSM 43827 pyruvate carboxylase YP_003103627.1 7015428 R 446462 CDS YP_003103628.1 256379968 8330181 7019075..7020478 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7020478 8330181 Amir_5974 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103628.1 7019075 D 446462 CDS YP_003103629.1 256379969 8330182 complement(7020612..7021439) 1 NC_013093.1 hypothetical protein 7021439 8330182 Amir_5975 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103629.1 7020612 R 446462 CDS YP_003103630.1 256379970 8330184 complement(7022476..7024677) 1 NC_013093.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 7024677 8330184 Amir_5977 Actinosynnema mirum DSM 43827 ATP-dependent DNA helicase RecG YP_003103630.1 7022476 R 446462 CDS YP_003103631.1 256379971 8330185 complement(7024732..7026369) 1 NC_013093.1 PFAM: Dak phosphatase; KEGG: bsu:BSU15840 hypothetical protein; Dak phosphatase 7026369 8330185 Amir_5978 Actinosynnema mirum DSM 43827 Dak phosphatase YP_003103631.1 7024732 R 446462 CDS YP_003103632.1 256379972 8330186 7026517..7026708 1 NC_013093.1 TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: aba:Acid345_0165 LSU ribosomal protein L28P; 50S ribosomal protein L28 7026708 8330186 Amir_5979 Actinosynnema mirum DSM 43827 50S ribosomal protein L28 YP_003103632.1 7026517 D 446462 CDS YP_003103633.1 256379973 8330187 complement(7026929..7027807) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4- dehydrorhamnose reductase; KEGG: ade:Adeh_4303 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 7027807 8330187 Amir_5980 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003103633.1 7026929 R 446462 CDS YP_003103634.1 256379974 8330188 7027887..7028381 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: acp:A2cp1_4259 transcriptional regulator, MarR family; MarR family transcriptional regulator 7028381 8330188 Amir_5981 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003103634.1 7027887 D 446462 CDS YP_003103635.1 256379975 8330189 complement(7028478..7029152) 1 NC_013093.1 PFAM: uracil-DNA glycosylase; KEGG: mxa:MXAN_0760 uracil-DNA glycosylase; uracil-DNA glycosylase 7029152 8330189 Amir_5982 Actinosynnema mirum DSM 43827 uracil-DNA glycosylase YP_003103635.1 7028478 R 446462 CDS YP_003103636.1 256379976 8330190 complement(7029167..7029685) 1 NC_013093.1 KEGG: sil:SPO1946 transferase family protein; transferase family protein 7029685 8330190 Amir_5983 Actinosynnema mirum DSM 43827 transferase family protein YP_003103636.1 7029167 R 446462 CDS YP_003103637.1 256379977 8330191 complement(7029708..7030223) 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hypothetical protein; GCN5-like N-acetyltransferase 7030223 8330191 Amir_5984 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103637.1 7029708 R 446462 CDS YP_003103638.1 256379978 8330192 complement(7030249..7031214) 1 NC_013093.1 KEGG: gur:Gura_0692 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; thiamine-monophosphate kinase 7031214 8330192 Amir_5985 Actinosynnema mirum DSM 43827 thiamine-monophosphate kinase YP_003103638.1 7030249 R 446462 CDS YP_003103639.1 256379979 8330193 7031312..7031545 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: pzu:PHZ_c3044 transcriptional regulator, Lrp/AsnC family; AsnC family transcriptional regulator 7031545 8330193 Amir_5986 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003103639.1 7031312 D 446462 CDS YP_003103640.1 256379980 8330194 7031614..7032156 1 NC_013093.1 hypothetical protein 7032156 8330194 Amir_5987 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103640.1 7031614 D 446462 CDS YP_003103641.1 256379981 8330195 complement(7032227..7033294) 1 NC_013093.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 7033294 ddl 8330195 ddl Actinosynnema mirum DSM 43827 D-alanyl-alanine synthetase A YP_003103641.1 7032227 R 446462 CDS YP_003103642.1 256379982 8330196 7033891..7034358 1 NC_013093.1 PFAM: cysteine dioxygenase type I; cupin; KEGG: mxa:MXAN_0927 cysteine dioxygenase, type I; cysteine dioxygenase type I 7034358 8330196 Amir_5989 Actinosynnema mirum DSM 43827 cysteine dioxygenase type I YP_003103642.1 7033891 D 446462 CDS YP_003103643.1 256379983 8330197 complement(7034433..7035080) 1 NC_013093.1 KEGG: aba:Acid345_2785 hypothetical protein; hypothetical protein 7035080 8330197 Amir_5990 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103643.1 7034433 R 446462 CDS YP_003103644.1 256379984 8330198 7035149..7036519 1 NC_013093.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: ade:Adeh_2233 GntR family transcriptional regulator; GntR family transcriptional regulator 7036519 8330198 Amir_5991 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003103644.1 7035149 D 446462 CDS YP_003103645.1 256379985 8330199 7036769..7037167 1 NC_013093.1 hypothetical protein 7037167 8330199 Amir_5992 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103645.1 7036769 D 446462 CDS YP_003103646.1 256379986 8330200 complement(7037214..7037408) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 7037408 8330200 Amir_5993 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103646.1 7037214 R 446462 CDS YP_003103647.1 256379987 8330201 complement(7037398..7038243) 1 NC_013093.1 hypothetical protein 7038243 8330201 Amir_5994 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103647.1 7037398 R 446462 CDS YP_003103648.1 256379988 8330202 7038481..7038954 1 NC_013093.1 KEGG: azc:AZC_3655 hypothetical protein; hypothetical protein 7038954 8330202 Amir_5995 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103648.1 7038481 D 446462 CDS YP_003103649.1 256379989 8330203 7038951..7039358 1 NC_013093.1 hypothetical protein 7039358 8330203 Amir_5996 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103649.1 7038951 D 446462 CDS YP_003103650.1 256379990 8330204 complement(7039404..7040531) 1 NC_013093.1 catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; cystathionine gamma-lyase 7040531 8330204 Amir_5997 Actinosynnema mirum DSM 43827 cystathionine gamma-lyase YP_003103650.1 7039404 R 446462 CDS YP_003103651.1 256379991 8330205 complement(7040531..7041532) 1 NC_013093.1 PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; ketopantoate reductase ApbA/PanE domain protein; NADP oxidoreductase coenzyme F420-dependent; KEGG: ade:Adeh_0396 glycerol-3-phosphate dehydrogenase (NAD(P)+); glycerol-3-phosphate dehydrogenase (NAD(P)(+)) 7041532 8330205 Amir_5998 Actinosynnema mirum DSM 43827 glycerol-3-phosphate dehydrogenase (NAD(P)(+)) YP_003103651.1 7040531 R 446462 CDS YP_003103652.1 256379992 8330206 complement(7041534..7042235) 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: ank:AnaeK_4035 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase 7042235 8330206 Amir_5999 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003103652.1 7041534 R 446462 CDS YP_003103653.1 256379993 8330207 7042317..7042931 1 NC_013093.1 KEGG: pzu:PHZ_c2537 hypothetical protein; hypothetical protein 7042931 8330207 Amir_6000 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103653.1 7042317 D 446462 CDS YP_003103654.1 256379994 8330208 7042904..7043218 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7043218 8330208 Amir_6001 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103654.1 7042904 D 446462 CDS YP_003103655.1 256379995 8330209 7043440..7045578 1 NC_013093.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 7045578 8330209 Amir_6002 Actinosynnema mirum DSM 43827 polyphosphate kinase YP_003103655.1 7043440 D 446462 CDS YP_003103656.1 256379996 8330210 7045582..7046526 1 NC_013093.1 PFAM: NUDIX hydrolase; phosphoglycerate mutase; KEGG: bja:bll6630 hypothetical protein; NUDIX hydrolase 7046526 8330210 Amir_6003 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003103656.1 7045582 D 446462 CDS YP_003103657.1 256379997 8330211 complement(7048316..7049173) 1 NC_013093.1 PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; KEGG: hypothetical protein LOC679057; histone family protein DNA-binding protein 7049173 8330211 Amir_6004 Actinosynnema mirum DSM 43827 histone family protein DNA-binding protein YP_003103657.1 7048316 R 446462 CDS YP_003103658.1 256379998 8330212 complement(7049381..7049983) 1 NC_013093.1 KEGG: aba:Acid345_2915 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; 3-isopropylmalate dehydratase, small subunit 7049983 8330212 Amir_6005 Actinosynnema mirum DSM 43827 3-isopropylmalate dehydratase, small subunit YP_003103658.1 7049381 R 446462 CDS YP_003103659.1 256379999 8330213 complement(7049998..7051416) 1 NC_013093.1 KEGG: aba:Acid345_2916 isopropylmalate isomerase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein; 3-isopropylmalate dehydratase, large subunit 7051416 8330213 Amir_6006 Actinosynnema mirum DSM 43827 3-isopropylmalate dehydratase, large subunit YP_003103659.1 7049998 R 446462 CDS YP_003103660.1 256380000 8330214 7051495..7052196 1 NC_013093.1 PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: cti:RALTA_B1947 transcriptional regulator, IclR family; IclR family transcriptional regulator 7052196 8330214 Amir_6007 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003103660.1 7051495 D 446462 CDS YP_003103661.1 256380001 8330218 complement(7053052..7053735) 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bha:BH0473 hypothetical protein; HAD superfamily hydrolase 7053735 8330218 Amir_6008 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003103661.1 7053052 R 446462 CDS YP_003103662.1 256380002 8330219 complement(7053894..7055384) 1 NC_013093.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 7055384 gltX 8330219 gltX Actinosynnema mirum DSM 43827 glutamyl-tRNA synthetase YP_003103662.1 7053894 R 446462 CDS YP_003103663.1 256380003 8330220 7055473..7056705 1 NC_013093.1 PFAM: monooxygenase FAD-binding; KEGG: mrd:Mrad2831_2174 monooxygenase FAD-binding; FAD-binding monooxygenase 7056705 8330220 Amir_6010 Actinosynnema mirum DSM 43827 FAD-binding monooxygenase YP_003103663.1 7055473 D 446462 CDS YP_003103664.1 256380004 8330221 complement(7056931..7057701) 1 NC_013093.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: scl:sce2870 fumarylacetoacetase; 5-oxopent-3-ene-1,2, 5-tricarboxylatedecarboxylase 7057701 8330221 Amir_6011 Actinosynnema mirum DSM 43827 5-oxopent-3-ene-1,2, 5-tricarboxylatedecarboxylase YP_003103664.1 7056931 R 446462 CDS YP_003103665.1 256380005 8330222 7057758..7058411 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7058411 8330222 Amir_6012 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103665.1 7057758 D 446462 CDS YP_003103666.1 256380006 8330223 complement(7058458..7060071) 1 NC_013093.1 TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: scl:sce3734 alpha- isopropylmalate/homocitrate synthase family transferase; alpha-isopropylmalate/homocitrate synthase family transferase 7060071 8330223 Amir_6013 Actinosynnema mirum DSM 43827 alpha-isopropylmalate/homocitrate synthase family transferase YP_003103666.1 7058458 R 446462 CDS YP_003103667.1 256380007 8330224 complement(7060690..7061727) 1 NC_013093.1 PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 7061727 8330224 Amir_6014 Actinosynnema mirum DSM 43827 3-isopropylmalate dehydrogenase YP_003103667.1 7060690 R 446462 CDS YP_003103668.1 256380008 8330225 complement(7062011..7065289) 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: glo:Glov_1721 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 7065289 8330225 Amir_6015 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003103668.1 7062011 R 446462 CDS YP_003103669.1 256380009 8330226 7065514..7065639 1 NC_013093.1 hypothetical protein 7065639 8330226 Amir_6016 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103669.1 7065514 D 446462 CDS YP_003103670.1 256380010 8330227 complement(7065728..7067326) 1 NC_013093.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 7067326 8330227 Amir_6017 Actinosynnema mirum DSM 43827 D-3-phosphoglycerate dehydrogenase YP_003103670.1 7065728 R 446462 CDS YP_003103671.1 256380011 8330228 complement(7067834..7068103) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 7068103 8330228 Amir_6018 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103671.1 7067834 R 446462 CDS YP_003103672.1 256380012 8330229 complement(7068216..7069229) 1 NC_013093.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 7069229 8330229 Amir_6019 Actinosynnema mirum DSM 43827 ketol-acid reductoisomerase YP_003103672.1 7068216 R 446462 CDS YP_003103673.1 256380013 8330230 complement(7069289..7069795) 1 NC_013093.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 7069795 ilvH 8330230 ilvH Actinosynnema mirum DSM 43827 acetolactate synthase 3 regulatory subunit YP_003103673.1 7069289 R 446462 CDS YP_003103674.1 256380014 8330231 complement(7069844..7071679) 1 NC_013093.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit 7071679 8330231 Amir_6021 Actinosynnema mirum DSM 43827 acetolactate synthase 1 catalytic subunit YP_003103674.1 7069844 R 446462 CDS YP_003103675.1 256380015 8330232 7071914..7072594 1 NC_013093.1 KEGG: mucin-associated surface protein (MASP); hypothetical protein 7072594 8330232 Amir_6022 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103675.1 7071914 D 446462 CDS YP_003103676.1 256380016 8330233 7072730..7073149 1 NC_013093.1 PFAM: vitamin K epoxide reductase; SMART: vitamin K epoxide reductase; KEGG: hypothetical protein; vitamin K epoxide reductase 7073149 8330233 Amir_6023 Actinosynnema mirum DSM 43827 vitamin K epoxide reductase YP_003103676.1 7072730 D 446462 CDS YP_003103677.1 256380017 8330234 7073265..7075109 1 NC_013093.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 7075109 8330234 Amir_6024 Actinosynnema mirum DSM 43827 dihydroxy-acid dehydratase YP_003103677.1 7073265 D 446462 CDS YP_003103678.1 256380018 8330235 complement(7075280..7076131) 1 NC_013093.1 PFAM: DoxX family protein; KEGG: slo:Shew_2277 DoxX family protein; DoxX family protein 7076131 8330235 Amir_6025 Actinosynnema mirum DSM 43827 DoxX family protein YP_003103678.1 7075280 R 446462 CDS YP_003103679.1 256380019 8330236 complement(7076321..7077031) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7077031 8330236 Amir_6026 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103679.1 7076321 R 446462 CDS YP_003103680.1 256380020 8330237 complement(7077291..7078169) 1 NC_013093.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: hypothetical protein; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 7078169 8330237 Amir_6027 Actinosynnema mirum DSM 43827 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_003103680.1 7077291 R 446462 CDS YP_003103681.1 256380021 8330238 7078195..7079148 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: afw:Anae109_2061 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 7079148 8330238 Amir_6028 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003103681.1 7078195 D 446462 CDS YP_003103682.1 256380022 8330239 7079181..7080338 1 NC_013093.1 KEGG: bha:BH2090 glucose dehydrogenase-B; glucose/sorbosone dehydrogenase-like protein 7080338 8330239 Amir_6029 Actinosynnema mirum DSM 43827 glucose/sorbosone dehydrogenase-like protein YP_003103682.1 7079181 D 446462 CDS YP_003103683.1 256380023 8330240 complement(7080370..7083012) 1 NC_013093.1 PFAM: hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: sus:Acid_3454 tetratricopeptide TPR_4; hypothetical protein 7083012 8330240 Amir_6030 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103683.1 7080370 R 446462 CDS YP_003103684.1 256380024 8330241 complement(7083104..7083466) 1 NC_013093.1 KEGG: clx-1; COllagen sequence X-hybridizing; hypothetical protein 7083466 8330241 Amir_6031 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103684.1 7083104 R 446462 CDS YP_003103685.1 256380025 8330242 complement(7083949..7085454) 1 NC_013093.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 7085454 gatB 8330242 gatB Actinosynnema mirum DSM 43827 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_003103685.1 7083949 R 446462 CDS YP_003103686.1 256380026 8330243 complement(7085451..7085642) 1 NC_013093.1 hypothetical protein 7085642 8330243 Amir_6033 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103686.1 7085451 R 446462 CDS YP_003103687.1 256380027 8330244 complement(7085639..7087159) 1 NC_013093.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 7087159 gatA 8330244 gatA Actinosynnema mirum DSM 43827 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_003103687.1 7085639 R 446462 CDS YP_003103688.1 256380028 8330245 complement(7087156..7087455) 1 NC_013093.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; KEGG: gsu:GSU3383 glutamyl-tRNA(Gln) amidotransferase, C subunit; glutamyl-tRNA(Gln) amidotransferase subunit C 7087455 8330245 Amir_6035 Actinosynnema mirum DSM 43827 glutamyl-tRNA(Gln) amidotransferase subunit C YP_003103688.1 7087156 R 446462 CDS YP_003103689.1 256380029 8330246 7087720..7088367 1 NC_013093.1 PFAM: amino acid-binding ACT domain protein; KEGG: bsu:BSU23550 malolactic enzyme; amino acid-binding ACT domain-containing protein 7088367 8330246 Amir_6036 Actinosynnema mirum DSM 43827 amino acid-binding ACT domain-containing protein YP_003103689.1 7087720 D 446462 CDS YP_003103690.1 256380030 8330247 7088486..7088974 1 NC_013093.1 PFAM: hypothetical protein; KEGG: mgm:Mmc1_2013 zinc finger, SWIM domain protein; hypothetical protein 7088974 8330247 Amir_6037 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103690.1 7088486 D 446462 CDS YP_003103691.1 256380031 8330248 complement(7089303..7091753) 1 NC_013093.1 KEGG: mca:MCA2438 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4- type; NAD-dependent DNA ligase OB-fold; SMART: NAD-dependent DNA ligase; BRCT domain protein; DNA ligase, NAD-dependent 7091753 8330248 Amir_6038 Actinosynnema mirum DSM 43827 DNA ligase, NAD-dependent YP_003103691.1 7089303 R 446462 CDS YP_003103692.1 256380032 8330249 complement(7091834..7092481) 1 NC_013093.1 hypothetical protein 7092481 8330249 Amir_6039 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103692.1 7091834 R 446462 CDS YP_003103693.1 256380033 8330250 complement(7092494..7093381) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: acr:Acry_2159 LysR family transcriptional regulator; LysR family transcriptional regulator 7093381 8330250 Amir_6040 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003103693.1 7092494 R 446462 CDS YP_003103694.1 256380034 8330251 7093393..7094259 1 NC_013093.1 PFAM: conserved hypothetical protein; KEGG: xau:Xaut_2089 hypothetical protein; hypothetical protein 7094259 8330251 Amir_6041 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103694.1 7093393 D 446462 CDS YP_003103695.1 256380035 8330252 complement(7094308..7095315) 1 NC_013093.1 PFAM: methionine synthase vitamin-B12 independent; KEGG: dal:Dalk_5194 hypothetical protein; methionine synthase vitamin-B12 independent 7095315 8330252 Amir_6042 Actinosynnema mirum DSM 43827 methionine synthase vitamin-B12 independent YP_003103695.1 7094308 R 446462 CDS YP_003103696.1 256380036 8330253 complement(7095423..7095752) 1 NC_013093.1 hypothetical protein 7095752 8330253 Amir_6043 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103696.1 7095423 R 446462 CDS YP_003103697.1 256380037 8330254 7095850..7096368 1 NC_013093.1 KEGG: bcb:BCB4264_A1184 hypothetical protein; hypothetical protein 7096368 8330254 Amir_6044 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103697.1 7095850 D 446462 CDS YP_003103698.1 256380038 8330255 complement(7096401..7097489) 1 NC_013093.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 7097489 mnmA 8330255 mnmA Actinosynnema mirum DSM 43827 tRNA-specific 2-thiouridylase MnmA YP_003103698.1 7096401 R 446462 CDS YP_003103699.1 256380039 8330256 complement(7097495..7098670) 1 NC_013093.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cysteine desulfurase NifS; K04487 cysteine desulfurase; class V aminotransferase 7098670 8330256 Amir_6046 Actinosynnema mirum DSM 43827 class V aminotransferase YP_003103699.1 7097495 R 446462 CDS YP_003103700.1 256380040 8330257 complement(7098670..7100217) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: dac:Daci_3895 major facilitator transporter; major facilitator superfamily protein 7100217 8330257 Amir_6047 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003103700.1 7098670 R 446462 CDS YP_003103701.1 256380041 8330258 complement(7100348..7101340) 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: cti:RALTA_A2392 phospholipid/glycerol acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase transmembrane protein; phospholipid/glycerol acyltransferase 7101340 8330258 Amir_6048 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003103701.1 7100348 R 446462 CDS YP_003103702.1 256380042 8330259 complement(7101340..7102110) 1 NC_013093.1 KEGG: eba:ebA5570 hypothetical protein; ornithine-acyl(acyl carrier protein) N- acyltransferase 7102110 8330259 Amir_6049 Actinosynnema mirum DSM 43827 ornithine-acyl(acyl carrier protein) N- acyltransferase YP_003103702.1 7101340 R 446462 CDS YP_003103703.1 256380043 8330260 complement(7102334..7103293) 1 NC_013093.1 PFAM: electron transfer flavoprotein alpha subunit; electron transfer flavoprotein alpha/beta-subunit; KEGG: met:M446_2006 electron transfer flavoprotein alpha subunit; electron transfer flavoprotein alpha subunit 7103293 8330260 Amir_6050 Actinosynnema mirum DSM 43827 electron transfer flavoprotein alpha subunit YP_003103703.1 7102334 R 446462 CDS YP_003103704.1 256380044 8330261 complement(7103314..7104093) 1 NC_013093.1 PFAM: electron transfer flavoprotein alpha/beta- subunit; KEGG: sat:SYN_02636 electron transfer flavoprotein beta-subunit; electron transfer flavoprotein alpha/beta- subunit 7104093 8330261 Amir_6051 Actinosynnema mirum DSM 43827 electron transfer flavoprotein alpha/beta- subunit YP_003103704.1 7103314 R 446462 CDS YP_003103705.1 256380045 8330262 7104349..7105191 1 NC_013093.1 TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: bsu:BSU11110 hypothetical protein; degV family protein 7105191 8330262 Amir_6052 Actinosynnema mirum DSM 43827 degV family protein YP_003103705.1 7104349 D 446462 CDS YP_003103706.1 256380046 8330263 7105268..7105411 1 NC_013093.1 hypothetical protein 7105411 8330263 Amir_6053 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103706.1 7105268 D 446462 CDS YP_003103707.1 256380047 8330264 complement(7105585..7107504) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7107504 8330264 Amir_6054 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103707.1 7105585 R 446462 CDS YP_003103708.1 256380048 8330265 complement(7107522..7108244) 1 NC_013093.1 KEGG: Eln; elastin; hypothetical protein 7108244 8330265 Amir_6055 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103708.1 7107522 R 446462 CDS YP_003103709.1 256380049 8330266 7108632..7109378 1 NC_013093.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: sus:Acid_7436 methyltransferase type 11; type 11 methyltransferase 7109378 8330266 Amir_6056 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003103709.1 7108632 D 446462 CDS YP_003103710.1 256380050 8330267 7109375..7110874 1 NC_013093.1 PFAM: glycoside hydrolase family 57; KEGG: scl:sce1626 hypothetical protein; glycoside hydrolase family protein 7110874 8330267 Amir_6057 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003103710.1 7109375 D 446462 CDS YP_003103711.1 256380051 8330268 7111116..7112369 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: bha:BH1415 hypothetical protein; group 1 glycosyl transferase 7112369 8330268 Amir_6058 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003103711.1 7111116 D 446462 CDS YP_003103712.1 256380052 8330269 complement(7112403..7112684) 1 NC_013093.1 hypothetical protein 7112684 8330269 Amir_6059 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103712.1 7112403 R 446462 CDS YP_003103713.1 256380053 8330270 complement(7112929..7113357) 1 NC_013093.1 KEGG: afw:Anae109_4021 dual specificity protein phosphatase; hypothetical protein 7113357 8330270 Amir_6060 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103713.1 7112929 R 446462 CDS YP_003103714.1 256380054 8330271 complement(7113391..7114137) 1 NC_013093.1 KEGG: bpy:Bphyt_6269 acetyltransferase; acetyltransferase (isoleucine patch superfamily)-like protein 7114137 8330271 Amir_6061 Actinosynnema mirum DSM 43827 acetyltransferase (isoleucine patch superfamily)-like protein YP_003103714.1 7113391 R 446462 CDS YP_003103715.1 256380055 8330272 7114207..7115139 1 NC_013093.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: asa:ASA_2899 ribonucleoside hydrolase 1; Inosine/uridine-preferring nucleoside hydrolase 7115139 8330272 Amir_6062 Actinosynnema mirum DSM 43827 Inosine/uridine-preferring nucleoside hydrolase YP_003103715.1 7114207 D 446462 CDS YP_003103716.1 256380056 8330273 complement(7115183..7116334) 1 NC_013093.1 hypothetical protein 7116334 8330273 Amir_6063 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103716.1 7115183 R 446462 CDS YP_003103717.1 256380057 8330274 complement(7116337..7117332) 1 NC_013093.1 PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: bja:bll7234 hypothetical protein; type 11 methyltransferase 7117332 8330274 Amir_6064 Actinosynnema mirum DSM 43827 type 11 methyltransferase YP_003103717.1 7116337 R 446462 CDS YP_003103718.1 256380058 8330275 complement(7117322..7118101) 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: dal:Dalk_2640 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 7118101 8330275 Amir_6065 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003103718.1 7117322 R 446462 CDS YP_003103719.1 256380059 8330276 complement(7118222..7119043) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sfu:Sfum_3281 ABC transporter; ABC transporter 7119043 8330276 Amir_6066 Actinosynnema mirum DSM 43827 ABC transporter YP_003103719.1 7118222 R 446462 CDS YP_003103720.1 256380060 8330277 7119238..7121343 1 NC_013093.1 KEGG: ade:Adeh_1056 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; glycogen debranching protein GlgX 7121343 8330277 Amir_6067 Actinosynnema mirum DSM 43827 glycogen debranching protein GlgX YP_003103720.1 7119238 D 446462 CDS YP_003103721.1 256380061 8330278 7121730..7122353 1 NC_013093.1 PFAM: cysteine dioxygenase type I; KEGG: mxa:MXAN_0927 cysteine dioxygenase, type I; cysteine dioxygenase type I 7122353 8330278 Amir_6068 Actinosynnema mirum DSM 43827 cysteine dioxygenase type I YP_003103721.1 7121730 D 446462 CDS YP_003103722.1 256380062 8330279 7122350..7122964 1 NC_013093.1 SMART: rhodanese domain protein; KEGG: hypothetical protein; rhodanese domain-containing protein 7122964 8330279 Amir_6069 Actinosynnema mirum DSM 43827 rhodanese domain-containing protein YP_003103722.1 7122350 D 446462 CDS YP_003103723.1 256380063 8330280 7123257..7124369 1 NC_013093.1 PFAM: hypothetical protein; KEGG: pin:Ping_0445 colicin uptake-like protein; hypothetical protein 7124369 8330280 Amir_6070 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103723.1 7123257 D 446462 CDS YP_003103724.1 256380064 8330281 complement(7124495..7127002) 1 NC_013093.1 KEGG: gsu:GSU0371 carbohydrate phosphorylase family protein; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; alpha-glucan phosphorylase 7127002 8330281 Amir_6071 Actinosynnema mirum DSM 43827 alpha-glucan phosphorylase YP_003103724.1 7124495 R 446462 CDS YP_003103725.1 256380065 8330282 7127911..7129890 1 NC_013093.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: afw:Anae109_3071 alpha amylase catalytic region; alpha amylase catalytic subunit 7129890 8330282 Amir_6072 Actinosynnema mirum DSM 43827 alpha amylase catalytic subunit YP_003103725.1 7127911 D 446462 CDS YP_003103726.1 256380066 8330283 7129983..7131797 1 NC_013093.1 KEGG: mxa:MXAN_3684 trehalose synthase; TIGRFAM: trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; trehalose synthase 7131797 8330283 Amir_6073 Actinosynnema mirum DSM 43827 trehalose synthase YP_003103726.1 7129983 D 446462 CDS YP_003103727.1 256380067 8330284 7131802..7133130 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: rce:RC1_0516 trehalose synthase; aminoglycoside phosphotransferase 7133130 8330284 Amir_6074 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003103727.1 7131802 D 446462 CDS YP_003103728.1 256380068 8330285 7133138..7135606 1 NC_013093.1 KEGG: mxa:MXAN_3682 glycogen branching enzyme; TIGRFAM: 1,4-alpha-glucan branching enzyme; PFAM: alpha amylase all-beta; glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; 1,4-alpha-glucan branching protein 7135606 8330285 Amir_6075 Actinosynnema mirum DSM 43827 1,4-alpha-glucan branching protein YP_003103728.1 7133138 D 446462 CDS YP_003103729.1 256380069 8330286 7135719..7137104 1 NC_013093.1 KEGG: mno:Mnod_6074 protein of unknown function zinc metallopeptidase; metalloprotease-like protein 7137104 8330286 Amir_6076 Actinosynnema mirum DSM 43827 metalloprotease-like protein YP_003103729.1 7135719 D 446462 CDS YP_003103730.1 256380070 8330287 complement(7137110..7137697) 1 NC_013093.1 hypothetical protein 7137697 8330287 Amir_6077 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103730.1 7137110 R 446462 CDS YP_003103731.1 256380071 8330288 7137917..7139365 1 NC_013093.1 PFAM: protein of unknown function zinc metallopeptidase KEGG: aba:Acid345_4616 protein of unknown function, zinc metallopeptidase; hypothetical protein 7139365 8330288 Amir_6078 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103731.1 7137917 D 446462 CDS YP_003103732.1 256380072 8330289 complement(7139477..7140457) 1 NC_013093.1 PFAM: Thioredoxin domain; KEGG: trx; thioredoxin; K05838 thioredoxin; thioredoxin domain-containing protein 7140457 8330289 Amir_6079 Actinosynnema mirum DSM 43827 thioredoxin domain-containing protein YP_003103732.1 7139477 R 446462 CDS YP_003103733.1 256380073 8330290 complement(7140479..7141618) 1 NC_013093.1 KEGG: bpd:BURPS668_A3050 hypothetical protein; hypothetical protein 7141618 8330290 Amir_6080 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103733.1 7140479 R 446462 CDS YP_003103734.1 256380074 8330291 complement(7141615..7141947) 1 NC_013093.1 PFAM: protein of unknown function DUF77; KEGG: mgm:Mmc1_2182 protein of unknown function DUF77; hypothetical protein 7141947 8330291 Amir_6081 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103734.1 7141615 R 446462 CDS YP_003103735.1 256380075 8330292 7141994..7142497 1 NC_013093.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bcz:BCZK0946 MarR family transcriptional regulator; MarR family transcriptional regulator 7142497 8330292 Amir_6082 Actinosynnema mirum DSM 43827 MarR family transcriptional regulator YP_003103735.1 7141994 D 446462 CDS YP_003103736.1 256380076 8330293 7143088..7144179 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce2125 hypothetical protein; aminoglycoside phosphotransferase 7144179 8330293 Amir_6083 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003103736.1 7143088 D 446462 CDS YP_003103737.1 256380077 8330294 complement(7144152..7144526) 1 NC_013093.1 KEGG: smt:Smal_2278 inner membrane protein; hypothetical protein 7144526 8330294 Amir_6084 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103737.1 7144152 R 446462 CDS YP_003103738.1 256380078 8330295 complement(7144523..7145461) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce5573 ABC transporter ATP- binding protein; ABC transporter 7145461 8330295 Amir_6085 Actinosynnema mirum DSM 43827 ABC transporter YP_003103738.1 7144523 R 446462 CDS YP_003103739.1 256380079 8330296 7145799..7146026 1 NC_013093.1 hypothetical protein 7146026 8330296 Amir_6086 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103739.1 7145799 D 446462 CDS YP_003103740.1 256380080 8330297 complement(7146005..7146847) 1 NC_013093.1 PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 7146847 8330297 Amir_6087 Actinosynnema mirum DSM 43827 transposase IS4 family protein YP_003103740.1 7146005 R 446462 CDS YP_003103741.1 256380081 8330298 7146939..7147112 1 NC_013093.1 hypothetical protein 7147112 8330298 Amir_6088 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103741.1 7146939 D 446462 CDS YP_003103742.1 256380082 8330299 7147130..7147651 1 NC_013093.1 hypothetical protein 7147651 8330299 Amir_6089 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103742.1 7147130 D 446462 CDS YP_003103743.1 256380083 8330300 7147746..7148789 1 NC_013093.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: smd:Smed_4315 periplasmic binding protein/LacI transcriptional regulator; LacI family transcriptional regulator 7148789 8330300 Amir_6090 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003103743.1 7147746 D 446462 CDS YP_003103744.1 256380084 8330301 7148786..7149805 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7149805 8330301 Amir_6091 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103744.1 7148786 D 446462 CDS YP_003103745.1 256380085 8330302 7149807..7150568 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: smd:Smed_0345 ABC transporter; ABC transporter 7150568 8330302 Amir_6092 Actinosynnema mirum DSM 43827 ABC transporter YP_003103745.1 7149807 D 446462 CDS YP_003103746.1 256380086 8330303 7150565..7151599 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: smd:Smed_0344 monosaccharide-transporting ATPase; Monosaccharide-transporting ATPase 7151599 8330303 Amir_6093 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003103746.1 7150565 D 446462 CDS YP_003103747.1 256380087 8330304 7151619..7152590 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rbsB; ABC transporter substrate binding protein (ribose); K10439 ribose transport system substrate-binding protein; LacI family transcriptional regulator 7152590 8330304 Amir_6094 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003103747.1 7151619 D 446462 CDS YP_003103748.1 256380088 8330305 complement(7152661..7153632) 1 NC_013093.1 KEGG: hne:HNE_0316 hypothetical protein; hypothetical protein 7153632 8330305 Amir_6095 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103748.1 7152661 R 446462 CDS YP_003103749.1 256380089 8330306 7153801..7155474 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein 7155474 8330306 Amir_6096 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003103749.1 7153801 D 446462 CDS YP_003103750.1 256380090 8330307 7155602..7157281 1 NC_013093.1 PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein 7157281 8330307 Amir_6097 Actinosynnema mirum DSM 43827 TAP domain-containing protein YP_003103750.1 7155602 D 446462 CDS YP_003103751.1 256380091 8330308 complement(7157747..7158403) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: bsu:BSU33080 hypothetical protein; LuxR family transcriptional regulator 7158403 8330308 Amir_6098 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003103751.1 7157747 R 446462 CDS YP_003103752.1 256380092 8330309 complement(7158441..7160018) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; KEGG: bce:BC2216 two-component sensor protein YhcY; GAF sensor signal transduction histidine kinase 7160018 8330309 Amir_6099 Actinosynnema mirum DSM 43827 GAF sensor signal transduction histidine kinase YP_003103752.1 7158441 R 446462 CDS YP_003103753.1 256380093 8330310 complement(7160015..7160419) 1 NC_013093.1 hypothetical protein 7160419 8330310 Amir_6100 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103753.1 7160015 R 446462 CDS YP_003103754.1 256380094 8330311 7160563..7161417 1 NC_013093.1 PFAM: N-acetyltransferase; KEGG: nar:Saro_0952 N-acetyltransferase; N-acetyltransferase 7161417 8330311 Amir_6101 Actinosynnema mirum DSM 43827 N-acetyltransferase YP_003103754.1 7160563 D 446462 CDS YP_003103755.1 256380095 8330312 complement(7161556..7162110) 1 NC_013093.1 hypothetical protein 7162110 8330312 Amir_6102 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103755.1 7161556 R 446462 CDS YP_003103756.1 256380096 8330313 complement(7162173..7162751) 1 NC_013093.1 hypothetical protein 7162751 8330313 Amir_6103 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103756.1 7162173 R 446462 CDS YP_003103757.1 256380097 8330314 complement(7162904..7164097) 1 NC_013093.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 7164097 8330314 Amir_6104 Actinosynnema mirum DSM 43827 acetyl-CoA acetyltransferase YP_003103757.1 7162904 R 446462 CDS YP_003103758.1 256380098 8330315 7164223..7164663 1 NC_013093.1 TIGRFAM: methylmalonyl-CoA epimerase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: gbm:Gbem_0558 methylmalonyl-CoA epimerase; methylmalonyl-CoA epimerase 7164663 8330315 Amir_6105 Actinosynnema mirum DSM 43827 methylmalonyl-CoA epimerase YP_003103758.1 7164223 D 446462 CDS YP_003103759.1 256380099 8330316 7164843..7166150 1 NC_013093.1 KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein 7166150 8330316 Amir_6106 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103759.1 7164843 D 446462 CDS YP_003103760.1 256380100 8330317 complement(7166325..7167020) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: mxa:MXAN_3278 hydrolase, alpha/beta fold family; alpha/beta hydrolase fold protein 7167020 8330317 Amir_6107 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003103760.1 7166325 R 446462 CDS YP_003103761.1 256380101 8330318 7167060..7167590 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_4010 acetyltransferase, GNAT family; GCN5-like N-acetyltransferase 7167590 8330318 Amir_6108 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103761.1 7167060 D 446462 CDS YP_003103762.1 256380102 8330319 complement(7167631..7167963) 1 NC_013093.1 hypothetical protein 7167963 8330319 Amir_6109 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103762.1 7167631 R 446462 CDS YP_003103763.1 256380103 8330320 7168081..7168290 1 NC_013093.1 TIGRFAM: regulatory protein, FmdB family; KEGG: mgm:Mmc1_2457 regulatory protein, FmdB family; FmdB family regulatory protein 7168290 8330320 Amir_6110 Actinosynnema mirum DSM 43827 FmdB family regulatory protein YP_003103763.1 7168081 D 446462 CDS YP_003103764.1 256380104 8330321 complement(7168381..7168944) 1 NC_013093.1 hypothetical protein 7168944 8330321 Amir_6111 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103764.1 7168381 R 446462 CDS YP_003103765.1 256380105 8330322 complement(7169121..7169861) 1 NC_013093.1 TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; KEGG: dde:Dde_1180 phosphoenolpyruvate--protein phosphotransferase; dihydroxyacetone kinase, phosphotransfer subunit 7169861 8330322 Amir_6112 Actinosynnema mirum DSM 43827 dihydroxyacetone kinase, phosphotransfer subunit YP_003103765.1 7169121 R 446462 CDS YP_003103766.1 256380106 8330323 complement(7169873..7170499) 1 NC_013093.1 TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: gdi:GDI0264 PTS-dependent dihydroxyacetone kinase; dihydroxyacetone kinase, L subunit 7170499 8330323 Amir_6113 Actinosynnema mirum DSM 43827 dihydroxyacetone kinase, L subunit YP_003103766.1 7169873 R 446462 CDS YP_003103767.1 256380107 8330324 complement(7170499..7171500) 1 NC_013093.1 KEGG: gdj:Gdia_2328 dihydroxyacetone kinase, DhaK subunit; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase; dihydroxyacetone kinase, DhaK subunit 7171500 8330324 Amir_6114 Actinosynnema mirum DSM 43827 dihydroxyacetone kinase, DhaK subunit YP_003103767.1 7170499 R 446462 CDS YP_003103768.1 256380108 8330325 complement(7171665..7173170) 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: aba:Acid345_1443 succinate-semialdehyde dehydrogenase (NAD(P)+); aldehyde dehydrogenase 7173170 8330325 Amir_6115 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003103768.1 7171665 R 446462 CDS YP_003103769.1 256380109 8330326 complement(7173238..7174299) 1 NC_013093.1 hypothetical protein 7174299 8330326 Amir_6116 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103769.1 7173238 R 446462 CDS YP_003103770.1 256380110 8330327 complement(7174348..7174626) 1 NC_013093.1 hypothetical protein 7174626 8330327 Amir_6117 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103770.1 7174348 R 446462 CDS YP_003103771.1 256380111 8330328 complement(7174636..7176324) 1 NC_013093.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: sus:Acid_3843 SSS family solute/sodium (Na+) symporter; SSS sodium solute transporter superfamily protein 7176324 8330328 Amir_6118 Actinosynnema mirum DSM 43827 SSS sodium solute transporter superfamily protein YP_003103771.1 7174636 R 446462 CDS YP_003103772.1 256380112 8330329 7176403..7177140 1 NC_013093.1 hypothetical protein 7177140 8330329 Amir_6119 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103772.1 7176403 D 446462 CDS YP_003103773.1 256380113 8330330 complement(7177164..7177493) 1 NC_013093.1 hypothetical protein 7177493 8330330 Amir_6120 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103773.1 7177164 R 446462 CDS YP_003103774.1 256380114 8330331 7177713..7178570 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bra:BRADO4105 transcriptional regulator; XRE family transcriptional regulator 7178570 8330331 Amir_6121 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103774.1 7177713 D 446462 CDS YP_003103775.1 256380115 8330332 7178586..7178771 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 7178771 8330332 Amir_6122 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103775.1 7178586 D 446462 CDS YP_003103776.1 256380116 8330333 complement(7178772..7179194) 1 NC_013093.1 KEGG: dar:Daro_0441 dihydrolipoamide acetyltransferase; dihydrolipoamide acetyltransferase 7179194 8330333 Amir_6123 Actinosynnema mirum DSM 43827 dihydrolipoamide acetyltransferase YP_003103776.1 7178772 R 446462 CDS YP_003103777.1 256380117 8330334 complement(7179369..7180028) 1 NC_013093.1 PFAM: protein of unknown function DUF91; KEGG: bvi:Bcep1808_6934 hypothetical protein; hypothetical protein 7180028 8330334 Amir_6124 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103777.1 7179369 R 446462 CDS YP_003103778.1 256380118 8330335 7180208..7180744 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: gdj:Gdia_2018 NUDIX hydrolase; NUDIX hydrolase 7180744 8330335 Amir_6125 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003103778.1 7180208 D 446462 CDS YP_003103779.1 256380119 8330336 7180741..7181331 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: asa:ASA_2273 acetyltransferase; GCN5-like N-acetyltransferase 7181331 8330336 Amir_6126 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103779.1 7180741 D 446462 CDS YP_003103780.1 256380120 8330337 complement(7181422..7182189) 1 NC_013093.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rfr:Rfer_0608 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 7182189 8330337 Amir_6127 Actinosynnema mirum DSM 43827 Enoyl-CoA hydratase/isomerase YP_003103780.1 7181422 R 446462 CDS YP_003103781.1 256380121 8330338 7182248..7182778 1 NC_013093.1 PFAM: isochorismatase hydrolase; KEGG: cvi:CV_1320 hypothetical protein; isochorismatase hydrolase 7182778 8330338 Amir_6128 Actinosynnema mirum DSM 43827 isochorismatase hydrolase YP_003103781.1 7182248 D 446462 CDS YP_003103782.1 256380122 8330339 7182860..7183156 1 NC_013093.1 hypothetical protein 7183156 8330339 Amir_6129 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103782.1 7182860 D 446462 CDS YP_003103783.1 256380123 8330340 7183273..7183638 1 NC_013093.1 hypothetical protein 7183638 8330340 Amir_6130 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103783.1 7183273 D 446462 CDS YP_003103784.1 256380124 8330341 7183643..7184173 1 NC_013093.1 hypothetical protein 7184173 8330341 Amir_6131 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103784.1 7183643 D 446462 CDS YP_003103785.1 256380125 8330342 complement(7184236..7185492) 1 NC_013093.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7185492 8330342 Amir_6132 Actinosynnema mirum DSM 43827 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_003103785.1 7184236 R 446462 CDS YP_003103786.1 256380126 8330343 7185575..7186147 1 NC_013093.1 TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: mmr:Mmar10_2358 ATP:cob(I)alamin adenosyltransferase; ATP/cobalamin adenosyltransferase 7186147 8330343 Amir_6133 Actinosynnema mirum DSM 43827 ATP/cobalamin adenosyltransferase YP_003103786.1 7185575 D 446462 CDS YP_003103787.1 256380127 8330344 complement(7186226..7186660) 1 NC_013093.1 hypothetical protein 7186660 8330344 Amir_6134 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103787.1 7186226 R 446462 CDS YP_003103788.1 256380128 8330345 complement(7186692..7187057) 1 NC_013093.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 7187057 atpC 8330345 atpC Actinosynnema mirum DSM 43827 F0F1 ATP synthase subunit epsilon YP_003103788.1 7186692 R 446462 CDS YP_003103789.1 256380129 8330346 complement(7187441..7188877) 1 NC_013093.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 7188877 8330346 Amir_6136 Actinosynnema mirum DSM 43827 F0F1 ATP synthase subunit beta YP_003103789.1 7187441 R 446462 CDS YP_003103790.1 256380130 8330347 complement(7188870..7189808) 1 NC_013093.1 KEGG: lpc:LPC_3298 F0F1 ATP synthase subunit gamma; TIGRFAM: ATP synthase F1, gamma subunit; PFAM: H+transporting two-sector ATPase gamma subunit; ATP synthase F1 subunit gamma 7189808 8330347 Amir_6137 Actinosynnema mirum DSM 43827 ATP synthase F1 subunit gamma YP_003103790.1 7188870 R 446462 CDS YP_003103791.1 256380131 8330348 complement(7189816..7191462) 1 NC_013093.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 7191462 8330348 Amir_6138 Actinosynnema mirum DSM 43827 F0F1 ATP synthase subunit alpha YP_003103791.1 7189816 R 446462 CDS YP_003103792.1 256380132 8330349 complement(7191527..7192354) 1 NC_013093.1 TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; KEGG: nwi:Nwi_0429 F0F1 ATP synthase subunit delta; ATP synthase F1 subunit delta 7192354 8330349 Amir_6139 Actinosynnema mirum DSM 43827 ATP synthase F1 subunit delta YP_003103792.1 7191527 R 446462 CDS YP_003103793.1 256380133 8330350 complement(7192363..7192911) 1 NC_013093.1 TIGRFAM: ATP synthase F0, B subunit; PFAM: H+transporting two-sector ATPase B/B' subunit; KEGG: ilo:IL2623 F0F1 ATP synthase subunit B; ATP synthase F0 subunit B 7192911 8330350 Amir_6140 Actinosynnema mirum DSM 43827 ATP synthase F0 subunit B YP_003103793.1 7192363 R 446462 CDS YP_003103794.1 256380134 8330351 complement(7192943..7193164) 1 NC_013093.1 TIGRFAM: ATP synthase F0, C subunit; PFAM: H+transporting two-sector ATPase C subunit; KEGG: atpH; ATPase III subunit; K02110 F-type H+- transporting ATPase subunit c; ATP synthase F0 subunit C 7193164 8330351 Amir_6141 Actinosynnema mirum DSM 43827 ATP synthase F0 subunit C YP_003103794.1 7192943 R 446462 CDS YP_003103795.1 256380135 8330352 complement(7193254..7194105) 1 NC_013093.1 TIGRFAM: ATP synthase F0, A subunit; PFAM: H+transporting two-sector ATPase A subunit; KEGG: acp:A2cp1_4495 ATP synthase F0, A subunit; ATP synthase F0 subunit A 7194105 8330352 Amir_6142 Actinosynnema mirum DSM 43827 ATP synthase F0 subunit A YP_003103795.1 7193254 R 446462 CDS YP_003103796.1 256380136 8330353 complement(7194083..7194292) 1 NC_013093.1 hypothetical protein 7194292 8330353 Amir_6143 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103796.1 7194083 R 446462 CDS YP_003103797.1 256380137 8330354 complement(7194339..7194716) 1 NC_013093.1 hypothetical protein 7194716 8330354 Amir_6144 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103797.1 7194339 R 446462 CDS YP_003103798.1 256380138 8330355 complement(7195245..7196414) 1 NC_013093.1 PFAM: glycosyl transferase family 4; KEGG: afw:Anae109_4433 glycosyl transferase family protein; glycosyl transferase family protein 7196414 8330355 Amir_6145 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003103798.1 7195245 R 446462 CDS YP_003103799.1 256380139 8330356 complement(7196486..7197136) 1 NC_013093.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: bca:BCE_5452 SUA5/YciO/YrdC/YwlC family protein; Sua5/YciO/YrdC/YwlC family protein 7197136 8330356 Amir_6146 Actinosynnema mirum DSM 43827 Sua5/YciO/YrdC/YwlC family protein YP_003103799.1 7196486 R 446462 CDS YP_003103800.1 256380140 8330357 complement(7197999..7198865) 1 NC_013093.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: rce:RC1_2636 modification methylase,HemK family; modification methylase, HemK family 7198865 8330357 Amir_6147 Actinosynnema mirum DSM 43827 modification methylase, HemK family YP_003103800.1 7197999 R 446462 CDS YP_003103801.1 256380141 8330358 complement(7198885..7200270) 1 NC_013093.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; dihydrolipoamide dehydrogenase 7200270 8330358 Amir_6148 Actinosynnema mirum DSM 43827 dihydrolipoamide dehydrogenase YP_003103801.1 7198885 R 446462 CDS YP_003103802.1 256380142 8330359 complement(7200631..7202742) 1 NC_013093.1 PFAM: BAAT/acyl-CoA thioester hydrolase; acyl-CoA thioester hydrolase/bile acid-CoA amino acid N- acetyltransferase; KEGG: sus:Acid_3161 palmitoyl-CoA hydrolase; BAAT/acyl-CoA thioester hydrolase 7202742 8330359 Amir_6149 Actinosynnema mirum DSM 43827 BAAT/acyl-CoA thioester hydrolase YP_003103802.1 7200631 R 446462 CDS YP_003103803.1 256380143 8330360 complement(7203084..7204148) 1 NC_013093.1 TIGRFAM: peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: lip:LI0002 peptide chain release factor 1; peptide chain release factor 1 7204148 8330360 Amir_6150 Actinosynnema mirum DSM 43827 peptide chain release factor 1 YP_003103803.1 7203084 R 446462 CDS YP_003103804.1 256380144 8330361 complement(7204231..7204443) 1 NC_013093.1 TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: tbd:Tbd_0039 50S ribosomal protein L31; 50S ribosomal protein L31 7204443 8330361 Amir_6151 Actinosynnema mirum DSM 43827 50S ribosomal protein L31 YP_003103804.1 7204231 R 446462 CDS YP_003103805.1 256380145 8330362 7204645..7205103 1 NC_013093.1 KEGG: mes:Meso_0153 chromate transporter, chromate ion transporter (CHR) family; hypothetical protein 7205103 8330362 Amir_6152 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103805.1 7204645 D 446462 CDS YP_003103806.1 256380146 8330363 complement(7205355..7207484) 1 NC_013093.1 KEGG: bba:Bd0065 transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; Rho termination factor domain protein; Rho termination factor RNA-binding; SMART: ATPase AAA; Cold shock protein; transcription termination factor Rho 7207484 8330363 Amir_6153 Actinosynnema mirum DSM 43827 transcription termination factor Rho YP_003103806.1 7205355 R 446462 CDS YP_003103807.1 256380147 8330364 complement(7207826..7208713) 1 NC_013093.1 KEGG: sus:Acid_0902 homoserine kinase; TIGRFAM: homoserine kinase; PFAM: GHMP kinase; GHMP kinase domain protein; homoserine kinase 7208713 8330364 Amir_6154 Actinosynnema mirum DSM 43827 homoserine kinase YP_003103807.1 7207826 R 446462 CDS YP_003103808.1 256380148 8330365 complement(7208710..7209786) 1 NC_013093.1 TIGRFAM: threonine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tgr:Tgr7_1440 threonine synthase; threonine synthase 7209786 8330365 Amir_6155 Actinosynnema mirum DSM 43827 threonine synthase YP_003103808.1 7208710 R 446462 CDS YP_003103809.1 256380149 8330366 complement(7209783..7211096) 1 NC_013093.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 7211096 8330366 Amir_6156 Actinosynnema mirum DSM 43827 homoserine dehydrogenase YP_003103809.1 7209783 R 446462 CDS YP_003103810.1 256380150 8330367 complement(7211099..7212523) 1 NC_013093.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: bsu:BSU23380 diaminopimelate decarboxylase; diaminopimelate decarboxylase 7212523 8330367 Amir_6157 Actinosynnema mirum DSM 43827 diaminopimelate decarboxylase YP_003103810.1 7211099 R 446462 CDS YP_003103811.1 256380151 8330368 complement(7212523..7214175) 1 NC_013093.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 7214175 argS 8330368 argS Actinosynnema mirum DSM 43827 arginyl-tRNA synthetase YP_003103811.1 7212523 R 446462 CDS YP_003103812.1 256380152 8330369 7214355..7215224 1 NC_013093.1 KEGG: scl:sce2901 hypothetical protein; hypothetical protein 7215224 8330369 Amir_6159 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103812.1 7214355 D 446462 CDS YP_003103813.1 256380153 8330370 7215226..7215987 1 NC_013093.1 PFAM: protein of unknown function DUF305; KEGG: mmr:Mmar10_0047 hypothetical protein; hypothetical protein 7215987 8330370 Amir_6160 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103813.1 7215226 D 446462 CDS YP_003103814.1 256380154 8330371 7216436..7220716 1 NC_013093.1 TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; coagulation factor 5/8 type domain protein; KEGG: sml:Smlt3935 glycosyltransferase; alpha-1,2-mannosidase 7220716 8330371 Amir_6161 Actinosynnema mirum DSM 43827 alpha-1,2-mannosidase YP_003103814.1 7216436 D 446462 CDS YP_003103815.1 256380155 8330372 complement(7220737..7221666) 1 NC_013093.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mpo:Mpop_4086 cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 7221666 8330372 Amir_6162 Actinosynnema mirum DSM 43827 cation diffusion facilitator family transporter YP_003103815.1 7220737 R 446462 CDS YP_003103816.1 256380156 8330374 complement(7222001..7223782) 1 NC_013093.1 PFAM: protein of unknown function DUF262; KEGG: xau:Xaut_2248 hypothetical protein; hypothetical protein 7223782 8330374 Amir_6163 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103816.1 7222001 R 446462 CDS YP_003103817.1 256380157 8330375 complement(7223880..7225718) 1 NC_013093.1 PFAM: glycoside hydrolase family 5; KEGG: pla:Plav_0833 hypothetical protein; glycoside hydrolase family protein 7225718 8330375 Amir_6164 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003103817.1 7223880 R 446462 CDS YP_003103818.1 256380158 8330376 complement(7225870..7227819) 1 NC_013093.1 hypothetical protein 7227819 8330376 Amir_6165 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103818.1 7225870 R 446462 CDS YP_003103819.1 256380159 8330377 complement(7228008..7231118) 1 NC_013093.1 PFAM: transcriptional activator domain; transcriptional regulator domain protein; SMART: ATPase AAA; KEGG: sus:Acid_5780 serine/threonine protein kinase; SARP family transcriptional regulator 7231118 8330377 Amir_6166 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003103819.1 7228008 R 446462 CDS YP_003103820.1 256380160 8330378 7231247..7232116 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: azo:azo0046 haloacetate dehalogenase; alpha/beta hydrolase fold protein 7232116 8330378 Amir_6167 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003103820.1 7231247 D 446462 CDS YP_003103821.1 256380161 8330379 complement(7232705..7233124) 1 NC_013093.1 SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 7233124 8330379 Amir_6168 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003103821.1 7232705 R 446462 CDS YP_003103822.1 256380162 8330380 7233262..7233492 1 NC_013093.1 hypothetical protein 7233492 8330380 Amir_6169 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103822.1 7233262 D 446462 CDS YP_003103823.1 256380163 8330381 7233882..7234148 1 NC_013093.1 hypothetical protein 7234148 8330381 Amir_6170 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103823.1 7233882 D 446462 CDS YP_003103824.1 256380164 8330382 complement(7234196..7235281) 1 NC_013093.1 KEGG: mca:MCA0835 fic family protein; hypothetical protein 7235281 8330382 Amir_6171 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103824.1 7234196 R 446462 CDS YP_003103825.1 256380165 8330383 complement(7235501..7236061) 1 NC_013093.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: mlo:mll5358 hypothetical protein; Activator of Hsp90 ATPase 1 family protein 7236061 8330383 Amir_6172 Actinosynnema mirum DSM 43827 Activator of Hsp90 ATPase 1 family protein YP_003103825.1 7235501 R 446462 CDS YP_003103826.1 256380166 8330384 7236310..7236786 1 NC_013093.1 PFAM: transcription activator effector binding; KEGG: aav:Aave_4607 transcription activator, effector binding; transcriptional activator ligand binding domain-containing protein 7236786 8330384 Amir_6173 Actinosynnema mirum DSM 43827 transcriptional activator ligand binding domain-containing protein YP_003103826.1 7236310 D 446462 CDS YP_003103827.1 256380167 8330385 7236935..7237816 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: pla:Plav_0210 luciferase family protein; luciferase-like monooxygenase 7237816 8330385 Amir_6174 Actinosynnema mirum DSM 43827 luciferase-like monooxygenase YP_003103827.1 7236935 D 446462 CDS YP_003103828.1 256380168 8330386 complement(7237910..7238944) 1 NC_013093.1 PFAM: GTPase EngC; SMART: ATPase AAA; KEGG: gsu:GSU2530 GTPase YjeQ; GTPase EngC 7238944 8330386 Amir_6175 Actinosynnema mirum DSM 43827 GTPase EngC YP_003103828.1 7237910 R 446462 CDS YP_003103829.1 256380169 8330387 7239655..7239750 1 NC_013093.1 hypothetical protein 7239750 8330387 Amir_6176 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103829.1 7239655 D 446462 CDS YP_003103830.1 256380170 8330388 7239815..7240942 1 NC_013093.1 PFAM: nitroreductase; KEGG: bcz:pE33L466_0413 NADH oxidase; nitroreductase 7240942 8330388 Amir_6177 Actinosynnema mirum DSM 43827 nitroreductase YP_003103830.1 7239815 D 446462 CDS YP_003103831.1 256380171 8330389 complement(7240986..7241966) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: stm:STM2406 oxidoreductase; aldo/keto reductase 7241966 8330389 Amir_6178 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003103831.1 7240986 R 446462 CDS YP_003103832.1 256380172 8330390 complement(7241974..7242828) 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: scl:sce0662 LacI family transcription regulator; LacI family transcriptional regulator 7242828 8330390 Amir_6179 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003103832.1 7241974 R 446462 CDS YP_003103833.1 256380173 8330391 complement(7242825..7245263) 1 NC_013093.1 KEGG: ret:RHE_CH00480 beta-mannosidase protein; beta-mannosidase protein 7245263 8330391 Amir_6180 Actinosynnema mirum DSM 43827 beta-mannosidase protein YP_003103833.1 7242825 R 446462 CDS YP_003103834.1 256380174 8330392 7245381..7247504 1 NC_013093.1 PFAM: glycoside hydrolase clan GH-D; KEGG: esa:ESA_03854 hypothetical protein; glycoside hydrolase family protein 7247504 8330392 Amir_6181 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003103834.1 7245381 D 446462 CDS YP_003103835.1 256380175 8330394 7247976..7248356 1 NC_013093.1 KEGG: cvi:CV_1450 hypothetical protein; hypothetical protein 7248356 8330394 Amir_6183 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103835.1 7247976 D 446462 CDS YP_003103836.1 256380176 8330396 complement(7248654..7249511) 1 NC_013093.1 PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: vsp:VS_II1529 ABC systems: ATP-binding protein; ABC transporter 7249511 8330396 Amir_6185 Actinosynnema mirum DSM 43827 ABC transporter YP_003103836.1 7248654 R 446462 CDS YP_003103837.1 256380177 8330397 complement(7249508..7251280) 1 NC_013093.1 PFAM: ABC transporter; binding-protein- dependent transport systems inner membrane component; SMART: ATPase AAA; KEGG: mxa:MXAN_6553 oligopeptide/dipeptide ABC transporter, permease/ATP-binding protein; ABC transporter 7251280 8330397 Amir_6186 Actinosynnema mirum DSM 43827 ABC transporter YP_003103837.1 7249508 R 446462 CDS YP_003103838.1 256380178 8330398 complement(7251294..7252283) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce4301 peptide ABC transporter, permease protein; ABC transporter inner membrane protein 7252283 8330398 Amir_6187 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003103838.1 7251294 R 446462 CDS YP_003103839.1 256380179 8330399 complement(7252288..7253970) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 5; KEGG: scl:sce4302 ABC-type dipeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 7253970 8330399 Amir_6188 Actinosynnema mirum DSM 43827 family 5 extracellular solute-binding protein YP_003103839.1 7252288 R 446462 CDS YP_003103840.1 256380180 8330400 7254148..7255356 1 NC_013093.1 PFAM: ROK family protein; KEGG: mxa:MXAN_6549 transcriptional regulator, ROK family; ROK family protein 7255356 8330400 Amir_6189 Actinosynnema mirum DSM 43827 ROK family protein YP_003103840.1 7254148 D 446462 CDS YP_003103841.1 256380181 8330401 complement(7255414..7255536) 1 NC_013093.1 hypothetical protein 7255536 8330401 Amir_6190 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103841.1 7255414 R 446462 CDS YP_003103842.1 256380182 8330402 complement(7255777..7257063) 1 NC_013093.1 KEGG: bav:BAV1845 monooxygenase; monooxygenase 7257063 8330402 Amir_6191 Actinosynnema mirum DSM 43827 monooxygenase YP_003103842.1 7255777 R 446462 CDS YP_003103843.1 256380183 8330403 complement(7257063..7258151) 1 NC_013093.1 KEGG: bav:BAV1846 monooxygenase; monooxygenase 7258151 8330403 Amir_6192 Actinosynnema mirum DSM 43827 monooxygenase YP_003103843.1 7257063 R 446462 CDS YP_003103844.1 256380184 8330404 complement(7258238..7259296) 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; KEGG: sus:Acid_5898 N-methyltryptophan oxidase; Sarcosine oxidase 7259296 8330404 Amir_6193 Actinosynnema mirum DSM 43827 Sarcosine oxidase YP_003103844.1 7258238 R 446462 CDS YP_003103845.1 256380185 8330405 complement(7259436..7260221) 1 NC_013093.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: ppd:Ppro_3005 HemK family modification methylase; modification methylase, HemK family 7260221 8330405 Amir_6194 Actinosynnema mirum DSM 43827 modification methylase, HemK family YP_003103845.1 7259436 R 446462 CDS YP_003103846.1 256380186 8330406 complement(7260387..7261649) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: scl:sce6417 ECF subfamily RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 7261649 8330406 Amir_6195 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103846.1 7260387 R 446462 CDS YP_003103847.1 256380187 8330407 complement(7261740..7262162) 1 NC_013093.1 PFAM: YCII-related; KEGG: bmj:BMULJ_04986 hypothetical protein; YCII-like protein 7262162 8330407 Amir_6196 Actinosynnema mirum DSM 43827 YCII-like protein YP_003103847.1 7261740 R 446462 CDS YP_003103848.1 256380188 8330408 complement(7262316..7263008) 1 NC_013093.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce0732 AraC family transcriptional regulator; AraC family transcriptional regulator 7263008 8330408 Amir_6197 Actinosynnema mirum DSM 43827 AraC family transcriptional regulator YP_003103848.1 7262316 R 446462 CDS YP_003103849.1 256380189 8330409 7263074..7263826 1 NC_013093.1 PFAM: NmrA family protein; KEGG: scl:sce0731 hypothetical protein; NmrA family protein 7263826 8330409 Amir_6198 Actinosynnema mirum DSM 43827 NmrA family protein YP_003103849.1 7263074 D 446462 CDS YP_003103850.1 256380190 8330410 complement(7263814..7265091) 1 NC_013093.1 KEGG: pzu:PHZ_c3387 hypothetical protein; PEP phosphonomutase-like protein 7265091 8330410 Amir_6199 Actinosynnema mirum DSM 43827 PEP phosphonomutase-like protein YP_003103850.1 7263814 R 446462 CDS YP_003103851.1 256380191 8330411 complement(7265142..7266098) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; KEGG: bxe:Bxe_C0078 zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 7266098 8330411 Amir_6200 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003103851.1 7265142 R 446462 CDS YP_003103852.1 256380192 8330412 7266202..7266771 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mxa:MXAN_2145 transcriptional regulator, TetR family; TetR family transcriptional regulator 7266771 8330412 Amir_6201 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003103852.1 7266202 D 446462 CDS YP_003103853.1 256380193 8330413 7267149..7267982 1 NC_013093.1 SMART: regulatory protein ArsR; KEGG: met:M446_4445 ArsR family transcriptional regulator; ArsR family transcriptional regulator 7267982 8330413 Amir_6202 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003103853.1 7267149 D 446462 CDS YP_003103854.1 256380194 8330414 complement(7267989..7268708) 1 NC_013093.1 PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: afw:Anae109_3817 protein phosphatase 2C-like protein; protein serine/threonine phosphatase 7268708 8330414 Amir_6203 Actinosynnema mirum DSM 43827 protein serine/threonine phosphatase YP_003103854.1 7267989 R 446462 CDS YP_003103855.1 256380195 8330415 complement(7268752..7269804) 1 NC_013093.1 PFAM: ROK family protein; KEGG: cvi:CV_2895 transcriptional regulator protein; ROK family protein 7269804 8330415 Amir_6204 Actinosynnema mirum DSM 43827 ROK family protein YP_003103855.1 7268752 R 446462 CDS YP_003103856.1 256380196 8330416 complement(7270095..7271231) 1 NC_013093.1 PFAM: beta-lactamase; KEGG: bcb:BCB4264_A3030 alkaline D-peptidase; Serine-type D-Ala-D-Ala carboxypeptidase 7271231 8330416 Amir_6205 Actinosynnema mirum DSM 43827 Serine-type D-Ala-D-Ala carboxypeptidase YP_003103856.1 7270095 R 446462 CDS YP_003103857.1 256380197 8330417 7271505..7273115 1 NC_013093.1 PFAM: glycoside hydrolase family 18; cellulose- binding family II; SMART: chitinase II; cellulose-binding family II; KEGG: cja:CJA_2611 endo-chitinase, , chi18D; glycoside hydrolase family protein 7273115 8330417 Amir_6206 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003103857.1 7271505 D 446462 CDS YP_003103858.1 256380198 8330418 complement(7273237..7275414) 1 NC_013093.1 KEGG: ppd:Ppro_0186 RecD/TraA family helicase; TIGRFAM: helicase, RecD/TraA family; SMART: ATPase AAA; helicase, RecD/TraA family 7275414 8330418 Amir_6207 Actinosynnema mirum DSM 43827 helicase, RecD/TraA family YP_003103858.1 7273237 R 446462 CDS YP_003103859.1 256380199 8330419 7275747..7276427 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 7276427 8330419 Amir_6208 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003103859.1 7275747 D 446462 CDS YP_003103860.1 256380200 8330420 7276424..7277455 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: lch:Lcho_2475 histidine kinase; histidine kinase 7277455 8330420 Amir_6209 Actinosynnema mirum DSM 43827 histidine kinase YP_003103860.1 7276424 D 446462 CDS YP_003103861.1 256380201 8330421 7277556..7279037 1 NC_013093.1 KEGG: pzu:PHZ_c1830 ABC transporter, ATP-binding protein CydD; hypothetical protein 7279037 8330421 Amir_6210 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103861.1 7277556 D 446462 CDS YP_003103862.1 256380202 8330422 7279229..7280404 1 NC_013093.1 PFAM: MscS Mechanosensitive ion channel; KEGG: bac:BamMC406_1797 MscS mechanosensitive ion channel; mechanosensitive ion channel MscS 7280404 8330422 Amir_6211 Actinosynnema mirum DSM 43827 mechanosensitive ion channel MscS YP_003103862.1 7279229 D 446462 CDS YP_003103863.1 256380203 8330423 7280443..7280994 1 NC_013093.1 KEGG: swi:Swit_4745 RND family efflux transporter MFP subunit; hypothetical protein 7280994 8330423 Amir_6212 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103863.1 7280443 D 446462 CDS YP_003103864.1 256380204 8330424 7281702..7284941 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: hypothetical protein; peptidase S8/S53 subtilisin kexin sedolisin 7284941 8330424 Amir_6213 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003103864.1 7281702 D 446462 CDS YP_003103865.1 256380205 8330425 7285109..7286764 1 NC_013093.1 proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 7286764 8330425 Amir_6214 Actinosynnema mirum DSM 43827 FAD-binding dehydrogenase YP_003103865.1 7285109 D 446462 CDS YP_003103866.1 256380206 8330426 complement(7286799..7287638) 1 NC_013093.1 PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: dvu:DVU3313 LysR family transcriptional regulator; LysR family transcriptional regulator 7287638 8330426 Amir_6215 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003103866.1 7286799 R 446462 CDS YP_003103867.1 256380207 8330427 7287732..7288499 1 NC_013093.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: ccv:CCV52592_0326 NADP oxidoreductase, coenzyme F420-dependent; NADP oxidoreductase coenzyme F420-dependent 7288499 8330427 Amir_6216 Actinosynnema mirum DSM 43827 NADP oxidoreductase coenzyme F420-dependent YP_003103867.1 7287732 D 446462 CDS YP_003103868.1 256380208 8330428 complement(7288503..7288979) 1 NC_013093.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: dac:Daci_0096 flavin reductase domain- containing protein; flavin reductase domain-containing protein 7288979 8330428 Amir_6217 Actinosynnema mirum DSM 43827 flavin reductase domain-containing protein YP_003103868.1 7288503 R 446462 CDS YP_003103869.1 256380209 8330429 complement(7289247..7290017) 1 NC_013093.1 hypothetical protein 7290017 8330429 Amir_6218 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103869.1 7289247 R 446462 CDS YP_003103870.1 256380210 8330430 complement(7290014..7291804) 1 NC_013093.1 KEGG: GH21940 gene product from transcript GH21940- RA; hypothetical protein 7291804 8330430 Amir_6219 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103870.1 7290014 R 446462 CDS YP_003103871.1 256380211 8330431 complement(7291818..7292267) 1 NC_013093.1 hypothetical protein 7292267 8330431 Amir_6220 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103871.1 7291818 R 446462 CDS YP_003103872.1 256380212 8330432 7292367..7295162 1 NC_013093.1 PFAM: transcriptional activator domain; hypothetical protein; hypothetical protein; NB- ARC domain protein; transcriptional regulator domain protein; SMART: ATPase AAA; hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator 7295162 8330432 Amir_6221 Actinosynnema mirum DSM 43827 SARP family transcriptional regulator YP_003103872.1 7292367 D 446462 CDS YP_003103873.1 256380213 8330433 complement(7295607..7297466) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7297466 8330433 Amir_6222 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103873.1 7295607 R 446462 CDS YP_003103874.1 256380214 8330434 7298025..7300133 1 NC_013093.1 KEGG: pfl:PFL_0190 sensory box-containing diguanylate cyclase, TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat- containing protein; EAL domain protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 7300133 8330434 Amir_6223 Actinosynnema mirum DSM 43827 PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase YP_003103874.1 7298025 D 446462 CDS YP_003103875.1 256380215 8330435 7300267..7301118 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: shw:Sputw3181_3433 protease Do; peptidase S1 and S6 chymotrypsin/Hap 7301118 8330435 Amir_6224 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003103875.1 7300267 D 446462 CDS YP_003103876.1 256380216 8330436 7301255..7302844 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: aeh:Mlg_1719 acyl-CoA dehydrogenase domain- containing protein; acyl-CoA dehydrogenase domain-containing protein 7302844 8330436 Amir_6225 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003103876.1 7301255 D 446462 CDS YP_003103877.1 256380217 8330437 7302856..7303602 1 NC_013093.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 7303602 8330437 Amir_6226 Actinosynnema mirum DSM 43827 enoyl-CoA hydratase YP_003103877.1 7302856 D 446462 CDS YP_003103878.1 256380218 8330438 complement(7303651..7303959) 1 NC_013093.1 hypothetical protein 7303959 8330438 Amir_6227 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103878.1 7303651 R 446462 CDS YP_003103879.1 256380219 8330439 complement(7303970..7305121) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: reu:Reut_C6425 butyryl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 7305121 8330439 Amir_6228 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003103879.1 7303970 R 446462 CDS YP_003103880.1 256380220 8330440 complement(7305127..7307058) 1 NC_013093.1 PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; biotin/lipoyl attachment domain-containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: mag:amb0674 acetyl-/propionyl-coenzyme A carboxylase alpha chain; carbamoyl-phosphate synthase L chain ATP- binding 7307058 8330440 Amir_6229 Actinosynnema mirum DSM 43827 carbamoyl-phosphate synthase L chain ATP- binding YP_003103880.1 7305127 R 446462 CDS YP_003103881.1 256380221 8330441 complement(7307058..7308659) 1 NC_013093.1 PFAM: carboxyl transferase; KEGG: bmj:BMULJ_05049 propionyl-CoA carboxylase beta chain; propionyl-CoA carboxylase 7308659 8330441 Amir_6230 Actinosynnema mirum DSM 43827 propionyl-CoA carboxylase YP_003103881.1 7307058 R 446462 CDS YP_003103882.1 256380222 8330442 7309015..7309608 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: reu:Reut_B5488 TetR family transcriptional regulator; TetR family transcriptional regulator 7309608 8330442 Amir_6231 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003103882.1 7309015 D 446462 CDS YP_003103883.1 256380223 8330443 7310055..7312226 1 NC_013093.1 KEGG: mxa:MXAN_4195 hypothetical protein; hypothetical protein 7312226 8330443 Amir_6232 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103883.1 7310055 D 446462 CDS YP_003103884.1 256380224 8330445 complement(7313339..7314043) 1 NC_013093.1 PFAM: protein of unknown function DUF1023; KEGG: hypothetical protein; hypothetical protein 7314043 8330445 Amir_6234 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103884.1 7313339 R 446462 CDS YP_003103885.1 256380225 8330446 complement(7314096..7314743) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 7314743 8330446 Amir_6235 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003103885.1 7314096 R 446462 CDS YP_003103886.1 256380226 8330447 complement(7314917..7316080) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 7316080 8330447 Amir_6236 Actinosynnema mirum DSM 43827 histidine kinase YP_003103886.1 7314917 R 446462 CDS YP_003103887.1 256380227 8330448 7316238..7316738 1 NC_013093.1 hypothetical protein 7316738 8330448 Amir_6237 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103887.1 7316238 D 446462 CDS YP_003103888.1 256380228 8330449 7316946..7318604 1 NC_013093.1 PFAM: cellulose-binding family II; Fibronectin type III domain protein; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: azc:AZC_2901 type III fibronectin; cellulose-binding family protein 7318604 8330449 Amir_6238 Actinosynnema mirum DSM 43827 cellulose-binding family protein YP_003103888.1 7316946 D 446462 CDS YP_003103889.1 256380229 8330450 complement(7318588..7319619) 1 NC_013093.1 KEGG: ank:AnaeK_2457 homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; homoserine O-acetyltransferase 7319619 8330450 Amir_6239 Actinosynnema mirum DSM 43827 homoserine O-acetyltransferase YP_003103889.1 7318588 R 446462 CDS YP_003103890.1 256380230 8330451 complement(7319616..7320905) 1 NC_013093.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 7320905 8330451 Amir_6240 Actinosynnema mirum DSM 43827 O-acetylhomoserine aminocarboxypropyltransferase YP_003103890.1 7319616 R 446462 CDS YP_003103891.1 256380231 8330452 7321029..7322027 1 NC_013093.1 PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: scl:sce9140 oxidoreductase; oxidoreductase domain-containing protein 7322027 8330452 Amir_6241 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003103891.1 7321029 D 446462 CDS YP_003103892.1 256380232 8330453 complement(7322029..7322373) 1 NC_013093.1 hypothetical protein 7322373 8330453 Amir_6242 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103892.1 7322029 R 446462 CDS YP_003103893.1 256380233 8330454 complement(7322612..7323298) 1 NC_013093.1 hypothetical protein 7323298 8330454 Amir_6243 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103893.1 7322612 R 446462 CDS YP_003103894.1 256380234 8330455 7323444..7323863 1 NC_013093.1 PFAM: proteinase inhibitor I16 subtilisin-type inhibitor; proteinase inhibitor I16 subtilisin-type inhibitor 7323863 8330455 Amir_6244 Actinosynnema mirum DSM 43827 proteinase inhibitor I16 subtilisin-type inhibitor YP_003103894.1 7323444 D 446462 CDS YP_003103895.1 256380235 8330456 7324109..7324600 1 NC_013093.1 PFAM: glutathione peroxidase; KEGG: pap:PSPA7_4682 glutathione peroxidase; glutathione peroxidase 7324600 8330456 Amir_6245 Actinosynnema mirum DSM 43827 glutathione peroxidase YP_003103895.1 7324109 D 446462 CDS YP_003103896.1 256380236 8330457 complement(7324742..7326109) 1 NC_013093.1 KEGG: pap:PSPA7_2808 L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 7326109 8330457 Amir_6246 Actinosynnema mirum DSM 43827 L-serine dehydratase 1 YP_003103896.1 7324742 R 446462 CDS YP_003103897.1 256380237 8330458 complement(7326113..7326496) 1 NC_013093.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; KEGG: bcr:BCAH187_A5133 glycine cleavage system H protein; glycine cleavage system H protein 7326496 8330458 Amir_6247 Actinosynnema mirum DSM 43827 glycine cleavage system H protein YP_003103897.1 7326113 R 446462 CDS YP_003103898.1 256380238 8330459 7326907..7328013 1 NC_013093.1 KEGG: dar:Daro_2145 L-alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; alanine dehydrogenase 7328013 8330459 Amir_6248 Actinosynnema mirum DSM 43827 alanine dehydrogenase YP_003103898.1 7326907 D 446462 CDS YP_003103899.1 256380239 8330460 7328700..7329122 1 NC_013093.1 hypothetical protein 7329122 8330460 Amir_6249 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103899.1 7328700 D 446462 CDS YP_003103900.1 256380240 8330461 7329173..7330546 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ccs:CCNA_03389 lantibiotic transport ATP- binding protein; ABC transporter 7330546 8330461 Amir_6250 Actinosynnema mirum DSM 43827 ABC transporter YP_003103900.1 7329173 D 446462 CDS YP_003103901.1 256380241 8330462 7330546..7331421 1 NC_013093.1 hypothetical protein 7331421 8330462 Amir_6251 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103901.1 7330546 D 446462 CDS YP_003103902.1 256380242 8330463 7331430..7335740 1 NC_013093.1 PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: see:SNSL254_A2969 ATP binding cassette; ABC transporter 7335740 8330463 Amir_6252 Actinosynnema mirum DSM 43827 ABC transporter YP_003103902.1 7331430 D 446462 CDS YP_003103903.1 256380243 8330464 7337165..7340893 1 NC_013093.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase 7340893 kgd 8330464 kgd Actinosynnema mirum DSM 43827 alpha-ketoglutarate decarboxylase YP_003103903.1 7337165 D 446462 CDS YP_003103904.1 256380244 8330465 7340900..7341082 1 NC_013093.1 hypothetical protein 7341082 8330465 Amir_6254 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103904.1 7340900 D 446462 CDS YP_003103905.1 256380245 8330466 complement(7341204..7341788) 1 NC_013093.1 KEGG: GF17241 gene product from transcript GF17241- RA; hypothetical protein 7341788 8330466 Amir_6255 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103905.1 7341204 R 446462 CDS YP_003103906.1 256380246 8330467 complement(7341839..7342843) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: scl:sce5264 sugar-phosphate dehydrogenase; aldo/keto reductase 7342843 8330467 Amir_6256 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003103906.1 7341839 R 446462 CDS YP_003103907.1 256380247 8330468 complement(7342888..7343943) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; SMART: helix-turn-helix domain protein; KEGG: ppd:Ppro_0104 helix-turn-helix domain- containing protein; helix-turn-helix domain-containing protein 7343943 8330468 Amir_6257 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003103907.1 7342888 R 446462 CDS YP_003103908.1 256380248 8330469 complement(7343936..7344682) 1 NC_013093.1 hypothetical protein 7344682 8330469 Amir_6258 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103908.1 7343936 R 446462 CDS YP_003103909.1 256380249 8330470 complement(7344887..7347259) 1 NC_013093.1 PFAM: NB-ARC domain protein; KEGG: scl:sce5225 protein kinase; NB-ARC domain-containing protein 7347259 8330470 Amir_6259 Actinosynnema mirum DSM 43827 NB-ARC domain-containing protein YP_003103909.1 7344887 R 446462 CDS YP_003103910.1 256380250 8330471 complement(7347256..7347849) 1 NC_013093.1 hypothetical protein 7347849 8330471 Amir_6260 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103910.1 7347256 R 446462 CDS YP_003103911.1 256380251 8330472 complement(7347846..7348121) 1 NC_013093.1 hypothetical protein 7348121 8330472 Amir_6261 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103911.1 7347846 R 446462 CDS YP_003103912.1 256380252 8330473 complement(7348314..7349459) 1 NC_013093.1 catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 7349459 8330473 Amir_6262 Actinosynnema mirum DSM 43827 imidazolonepropionase YP_003103912.1 7348314 R 446462 CDS YP_003103913.1 256380253 8330474 complement(7349536..7350825) 1 NC_013093.1 TIGRFAM: formiminoglutamate deiminase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: pzu:PHZ_c0464 formiminoglutamate deiminase; formiminoglutamate deiminase 7350825 8330474 Amir_6263 Actinosynnema mirum DSM 43827 formiminoglutamate deiminase YP_003103913.1 7349536 R 446462 CDS YP_003103914.1 256380254 8330475 complement(7350986..7352161) 1 NC_013093.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 7352161 8330475 Amir_6264 Actinosynnema mirum DSM 43827 allantoate amidohydrolase YP_003103914.1 7350986 R 446462 CDS YP_003103915.1 256380255 8330476 complement(7352158..7353804) 1 NC_013093.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 7353804 8330476 Amir_6265 Actinosynnema mirum DSM 43827 urocanate hydratase YP_003103915.1 7352158 R 446462 CDS YP_003103916.1 256380256 8330477 complement(7353798..7355309) 1 NC_013093.1 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 7355309 8330477 Amir_6266 Actinosynnema mirum DSM 43827 histidine ammonia-lyase YP_003103916.1 7353798 R 446462 CDS YP_003103917.1 256380257 8330478 7355768..7356547 1 NC_013093.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: cti:RALTA_B0569 transcriptional regulator, IclR family; IclR family transcriptional regulator 7356547 8330478 Amir_6267 Actinosynnema mirum DSM 43827 IclR family transcriptional regulator YP_003103917.1 7355768 D 446462 CDS YP_003103918.1 256380258 8330479 complement(7356599..7357483) 1 NC_013093.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: opuAC; substrate-binding region of ABC-type glycine betaine transport system; glycine/betaine ABC transporter substrate-binding protein 7357483 8330479 Amir_6268 Actinosynnema mirum DSM 43827 glycine/betaine ABC transporter substrate-binding protein YP_003103918.1 7356599 R 446462 CDS YP_003103919.1 256380259 8330480 complement(7357480..7358211) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ABC transporter; K05846 osmoprotectant transport system permease protein; ABC transporter inner membrane protein 7358211 8330480 Amir_6269 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003103919.1 7357480 R 446462 CDS YP_003103920.1 256380260 8330481 complement(7358208..7358864) 1 NC_013093.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: proline/glycine betaine ABC transporter; K05846 osmoprotectant transport system permease protein; ABC transporter inner membrane protein 7358864 8330481 Amir_6270 Actinosynnema mirum DSM 43827 ABC transporter inner membrane protein YP_003103920.1 7358208 R 446462 CDS YP_003103921.1 256380261 8330482 complement(7358857..7359939) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ABC transporter nucleotide binding/ATPase protein (proline/glycine/betaine); ABC transporter 7359939 8330482 Amir_6271 Actinosynnema mirum DSM 43827 ABC transporter YP_003103921.1 7358857 R 446462 CDS YP_003103922.1 256380262 8330483 7360096..7361655 1 NC_013093.1 PFAM: protein of unknown function DUF43; KEGG: rpb:RPB_2044 hypothetical protein; hypothetical protein 7361655 8330483 Amir_6272 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103922.1 7360096 D 446462 CDS YP_003103923.1 256380263 8330484 complement(7361683..7362294) 1 NC_013093.1 hypothetical protein 7362294 8330484 Amir_6273 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103923.1 7361683 R 446462 CDS YP_003103924.1 256380264 8330485 complement(7362358..7362981) 1 NC_013093.1 hypothetical protein 7362981 8330485 Amir_6274 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103924.1 7362358 R 446462 CDS YP_003103925.1 256380265 8330486 complement(7362978..7364222) 1 NC_013093.1 KEGG: rru:Rru_A3216 hypothetical protein; hypothetical protein 7364222 8330486 Amir_6275 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103925.1 7362978 R 446462 CDS YP_003103926.1 256380266 8330487 complement(7364222..7364530) 1 NC_013093.1 hypothetical protein 7364530 8330487 Amir_6276 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103926.1 7364222 R 446462 CDS YP_003103927.1 256380267 8330488 complement(7364527..7365048) 1 NC_013093.1 KEGG: dac:Daci_5082 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 7365048 8330488 Amir_6277 Actinosynnema mirum DSM 43827 methyl-accepting chemotaxis sensory transducer YP_003103927.1 7364527 R 446462 CDS YP_003103928.1 256380268 8330489 complement(7365181..7368375) 1 NC_013093.1 KEGG: tbd:Tbd_1456 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 7368375 8330489 Amir_6278 Actinosynnema mirum DSM 43827 PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase YP_003103928.1 7365181 R 446462 CDS YP_003103929.1 256380269 8330490 complement(7368614..7369792) 1 NC_013093.1 PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: bcb:BCB4264_A4713 malate dehydrogenase; malate dehydrogenase 7369792 8330490 Amir_6279 Actinosynnema mirum DSM 43827 malate dehydrogenase YP_003103929.1 7368614 R 446462 CDS YP_003103930.1 256380270 8330491 7370108..7370704 1 NC_013093.1 KEGG: ecw:EcE24377A_2329 dTDP-4-dehydrorhamnose 3,5- epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 7370704 8330491 Amir_6280 Actinosynnema mirum DSM 43827 dTDP-4-dehydrorhamnose 3,5-epimerase YP_003103930.1 7370108 D 446462 CDS YP_003103931.1 256380271 8330492 complement(7370708..7371037) 1 NC_013093.1 TIGRFAM: nickel-type superoxide dismutase maturation protease; PFAM: peptidase S24 and S26 domain protein; KEGG: peptidase S24-like domain containing protein; K09647 mitochondrial inner membrane protease subunit 1; phage repressor 7371037 8330492 Amir_6281 Actinosynnema mirum DSM 43827 phage repressor YP_003103931.1 7370708 R 446462 CDS YP_003103932.1 256380272 8330493 7371115..7371531 1 NC_013093.1 KEGG: mmw:Mmwyl1_1415 superoxide dismutase Ni-type; TIGRFAM: superoxide dismutase, Ni; PFAM: superoxide dismutase Ni-type; superoxide dismutase, Ni 7371531 8330493 Amir_6282 Actinosynnema mirum DSM 43827 superoxide dismutase, Ni YP_003103932.1 7371115 D 446462 CDS YP_003103933.1 256380273 8330494 complement(7371611..7372714) 1 NC_013093.1 KEGG: bur:Bcep18194_B0516 hypothetical protein; hypothetical protein 7372714 8330494 Amir_6283 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103933.1 7371611 R 446462 CDS YP_003103934.1 256380274 8330495 7372905..7373513 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: rle:RL0954 phosphoglycerate mutase; phosphoglycerate mutase 7373513 8330495 Amir_6284 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003103934.1 7372905 D 446462 CDS YP_003103935.1 256380275 8330496 complement(7373630..7374421) 1 NC_013093.1 PFAM: protein of unknown function DUF574; KEGG: mxa:MXAN_2293 hypothetical protein; hypothetical protein 7374421 8330496 Amir_6285 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103935.1 7373630 R 446462 CDS YP_003103936.1 256380276 8330497 complement(7375145..7375897) 1 NC_013093.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: scl:sce6803 serine protease; peptidase S1 and S6 chymotrypsin/Hap 7375897 8330497 Amir_6286 Actinosynnema mirum DSM 43827 peptidase S1 and S6 chymotrypsin/Hap YP_003103936.1 7375145 R 446462 CDS YP_003103937.1 256380277 8330498 complement(7376046..7376447) 1 NC_013093.1 hypothetical protein 7376447 8330498 Amir_6287 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103937.1 7376046 R 446462 CDS YP_003103938.1 256380278 8330499 7376704..7377681 1 NC_013093.1 PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; KEGG: mag:amb0267 Sphingosine kinase and enzyme related to diacylglycerol kinase; diacylglycerol kinase catalytic subunit 7377681 8330499 Amir_6288 Actinosynnema mirum DSM 43827 diacylglycerol kinase catalytic subunit YP_003103938.1 7376704 D 446462 CDS YP_003103939.1 256380279 8330500 7377909..7378163 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 7378163 8330500 Amir_6289 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003103939.1 7377909 D 446462 CDS YP_003103940.1 256380280 8330501 complement(7378472..7379950) 1 NC_013093.1 PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: pca:Pcar_2710 hypothetical protein; signal transduction histidine kinase 7379950 8330501 Amir_6290 Actinosynnema mirum DSM 43827 signal transduction histidine kinase YP_003103940.1 7378472 R 446462 CDS YP_003103941.1 256380281 8330502 complement(7380328..7380720) 1 NC_013093.1 TIGRFAM: anti-sigma factor; KEGG: tgr:Tgr7_1713 transmembrane anti- sigma factor; anti-sigma factor 7380720 8330502 Amir_6291 Actinosynnema mirum DSM 43827 anti-sigma factor YP_003103941.1 7380328 R 446462 CDS YP_003103942.1 256380282 8330503 complement(7380717..7381376) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: scl:sce7566 ECF family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 7381376 8330503 Amir_6292 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003103942.1 7380717 R 446462 CDS YP_003103943.1 256380283 8330504 7381569..7382051 1 NC_013093.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: hch:HCH_01964 hypothetical protein; ybaK/ebsC protein 7382051 8330504 Amir_6293 Actinosynnema mirum DSM 43827 ybaK/ebsC protein YP_003103943.1 7381569 D 446462 CDS YP_003103944.1 256380284 8330505 complement(7382135..7382749) 1 NC_013093.1 KEGG: rle:pRL110093 hypothetical protein; hypothetical protein 7382749 8330505 Amir_6294 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103944.1 7382135 R 446462 CDS YP_003103945.1 256380285 8330506 complement(7382746..7383507) 1 NC_013093.1 PFAM: protein of unknown function DUF159; KEGG: dal:Dalk_1121 protein of unknown function DUF159; hypothetical protein 7383507 8330506 Amir_6295 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103945.1 7382746 R 446462 CDS YP_003103946.1 256380286 8330507 7383590..7384852 1 NC_013093.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 7384852 8330507 Amir_6296 Actinosynnema mirum DSM 43827 3-phosphoshikimate 1-carboxyvinyltransferase YP_003103946.1 7383590 D 446462 CDS YP_003103947.1 256380287 8330508 7384854..7385861 1 NC_013093.1 PFAM: GTPase EngC; KEGG: cvi:CV_2365 ribosome-associated GTPase; GTPase EngC 7385861 8330508 Amir_6297 Actinosynnema mirum DSM 43827 GTPase EngC YP_003103947.1 7384854 D 446462 CDS YP_003103948.1 256380288 8330509 7385998..7386375 1 NC_013093.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: slo:Shew_2437 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase 7386375 8330509 Amir_6298 Actinosynnema mirum DSM 43827 glyoxalase/bleomycin resistance protein/dioxygenase YP_003103948.1 7385998 D 446462 CDS YP_003103949.1 256380289 8330510 complement(7386397..7386906) 1 NC_013093.1 hypothetical protein 7386906 8330510 Amir_6299 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103949.1 7386397 R 446462 CDS YP_003103950.1 256380290 8330511 complement(7386903..7388291) 1 NC_013093.1 TIGRFAM: acyltransferase, WS/DGAT/MGAT; PFAM: protein of unknown function UPF0089; KEGG: maq:Maqu_3067 hypothetical protein; acyltransferase, WS/DGAT/MGAT 7388291 8330511 Amir_6300 Actinosynnema mirum DSM 43827 acyltransferase, WS/DGAT/MGAT YP_003103950.1 7386903 R 446462 CDS YP_003103951.1 256380291 8330512 complement(7388301..7388972) 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: mch:Mchl_2091 aminoglycoside phosphotransferase; Mn2+dependent serine/threonine protein kinase 7388972 8330512 Amir_6301 Actinosynnema mirum DSM 43827 Mn2+dependent serine/threonine protein kinase YP_003103951.1 7388301 R 446462 CDS YP_003103952.1 256380292 8330513 7389059..7389805 1 NC_013093.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sde:Sde_1711 von Willebrand factor, type A; TrmH family RNA methyltransferase 7389805 8330513 Amir_6302 Actinosynnema mirum DSM 43827 TrmH family RNA methyltransferase YP_003103952.1 7389059 D 446462 CDS YP_003103953.1 256380293 8330514 complement(7390196..7390597) 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: ACAD10; acyl-Coenzyme A dehydrogenase family, member 10; K11729 acyl-CoA dehydrogenase family member 10; HAD superfamily hydrolase 7390597 8330514 Amir_6303 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003103953.1 7390196 R 446462 CDS YP_003103954.1 256380294 8330515 7390663..7391040 1 NC_013093.1 hypothetical protein 7391040 8330515 Amir_6304 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103954.1 7390663 D 446462 CDS YP_003103955.1 256380295 8330516 complement(7391532..7394459) 1 NC_013093.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 7394459 8330516 Amir_6305 Actinosynnema mirum DSM 43827 preprotein translocase subunit SecA YP_003103955.1 7391532 R 446462 CDS YP_003103956.1 256380296 8330517 complement(7395702..7396370) 1 NC_013093.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: probable plastid-specific ribosomal protein PSRP-1 precursor; sigma 54 modulation protein/30S ribosomal protein S30EA 7396370 8330517 Amir_6306 Actinosynnema mirum DSM 43827 sigma 54 modulation protein/30S ribosomal protein S30EA YP_003103956.1 7395702 R 446462 CDS YP_003103957.1 256380297 8330518 complement(7396812..7397432) 1 NC_013093.1 KEGG: acp:A2cp1_0258 phosphoribosyltransferase; phosphoribosyltransferase 7397432 8330518 Amir_6307 Actinosynnema mirum DSM 43827 phosphoribosyltransferase YP_003103957.1 7396812 R 446462 CDS YP_003103958.1 256380298 8330519 complement(7397640..7399373) 1 NC_013093.1 KEGG: efe:EFER_0542 adhesin for cattle intestine colonization; hypothetical protein 7399373 8330519 Amir_6308 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103958.1 7397640 R 446462 CDS YP_003103959.1 256380299 8330520 complement(7399370..7401775) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase 7401775 8330520 Amir_6309 Actinosynnema mirum DSM 43827 histidine kinase YP_003103959.1 7399370 R 446462 CDS YP_003103960.1 256380300 8330521 complement(7401810..7402595) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator; winged helix family two component transcriptional regulator 7402595 8330521 Amir_6310 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003103960.1 7401810 R 446462 CDS YP_003103961.1 256380301 8330522 complement(7402688..7403320) 1 NC_013093.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 7403320 8330522 Amir_6311 Actinosynnema mirum DSM 43827 thymidylate kinase YP_003103961.1 7402688 R 446462 CDS YP_003103962.1 256380302 8330523 complement(7403398..7403622) 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 7403622 8330523 Amir_6312 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103962.1 7403398 R 446462 CDS YP_003103963.1 256380303 8330524 complement(7403643..7404527) 1 NC_013093.1 hypothetical protein 7404527 8330524 Amir_6313 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103963.1 7403643 R 446462 CDS YP_003103964.1 256380304 8330526 7405071..7405238 1 NC_013093.1 hypothetical protein 7405238 8330526 Amir_6315 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103964.1 7405071 D 446462 CDS YP_003103965.1 256380305 8330527 7405310..7407139 1 NC_013093.1 PFAM: asparagine synthase; KEGG: swi:Swit_4548 asparagine synthase; asparagine synthase 7407139 8330527 Amir_6316 Actinosynnema mirum DSM 43827 asparagine synthase YP_003103965.1 7405310 D 446462 CDS YP_003103966.1 256380306 8330528 7407136..7407900 1 NC_013093.1 KEGG: ank:AnaeK_0240 FAD dependent oxidoreductase; hypothetical protein 7407900 8330528 Amir_6317 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103966.1 7407136 D 446462 CDS YP_003103967.1 256380307 8330529 7407897..7408487 1 NC_013093.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vch:VCA0417 acetyltransferase; GCN5-like N-acetyltransferase 7408487 8330529 Amir_6318 Actinosynnema mirum DSM 43827 GCN5-like N-acetyltransferase YP_003103967.1 7407897 D 446462 CDS YP_003103968.1 256380308 8330531 7409428..7410336 1 NC_013093.1 hypothetical protein 7410336 8330531 Amir_6320 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103968.1 7409428 D 446462 CDS YP_003103969.1 256380309 8330532 complement(7410398..7411870) 1 NC_013093.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 7411870 8330532 Amir_6321 Actinosynnema mirum DSM 43827 S-adenosyl-L-homocysteine hydrolase YP_003103969.1 7410398 R 446462 CDS YP_003103970.1 256380310 8330533 complement(7412046..7413557) 1 NC_013093.1 PFAM: amino acid permease-associated region; aromatic amino acid permease; KEGG: rpi:Rpic_1962 amino acid permease-associated region; amino acid permease-associated protein 7413557 8330533 Amir_6322 Actinosynnema mirum DSM 43827 amino acid permease-associated protein YP_003103970.1 7412046 R 446462 CDS YP_003103971.1 256380311 8330534 complement(7413627..7414544) 1 NC_013093.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: hch:HCH_04023 Co/Zn/Cd cation transporter; cation diffusion facilitator family transporter 7414544 8330534 Amir_6323 Actinosynnema mirum DSM 43827 cation diffusion facilitator family transporter YP_003103971.1 7413627 R 446462 CDS YP_003103972.1 256380312 8330535 complement(7414605..7415828) 1 NC_013093.1 TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: scl:sce4699 mannose-6-phosphate isomerase; mannose-6-phosphate isomerase, class I 7415828 8330535 Amir_6324 Actinosynnema mirum DSM 43827 mannose-6-phosphate isomerase, class I YP_003103972.1 7414605 R 446462 CDS YP_003103973.1 256380313 8330536 complement(7415949..7417025) 1 NC_013093.1 KEGG: mch:Mchl_4903 double-strand break repair protein AddB; hypothetical protein 7417025 8330536 Amir_6325 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103973.1 7415949 R 446462 CDS YP_003103974.1 256380314 8330537 complement(7417032..7417223) 1 NC_013093.1 PFAM: protein of unknown function DUF343; KEGG: mes:Meso_3270 protein of unknown function DUF343; hypothetical protein 7417223 8330537 Amir_6326 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103974.1 7417032 R 446462 CDS YP_003103975.1 256380315 8330538 complement(7417251..7418603) 1 NC_013093.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase/phosphoglucomutase 7418603 manB 8330538 manB Actinosynnema mirum DSM 43827 phosphomannomutase/phosphoglucomutase YP_003103975.1 7417251 R 446462 CDS YP_003103976.1 256380316 8330539 complement(7418682..7419032) 1 NC_013093.1 hypothetical protein 7419032 8330539 Amir_6328 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103976.1 7418682 R 446462 CDS YP_003103977.1 256380317 8330540 7419187..7419639 1 NC_013093.1 KEGG: acp:A2cp1_1564 protein of unknown function DUF1025; hypothetical protein 7419639 8330540 Amir_6329 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103977.1 7419187 D 446462 CDS YP_003103978.1 256380318 8330541 complement(7420144..7424043) 1 NC_013093.1 KEGG: GF17743 gene product from transcript GF17743- RA; glycosyltransferase-like protein 7424043 8330541 Amir_6330 Actinosynnema mirum DSM 43827 glycosyltransferase-like protein YP_003103978.1 7420144 R 446462 CDS YP_003103979.1 256380319 8330542 complement(7424259..7424567) 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 7424567 8330542 Amir_6331 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003103979.1 7424259 R 446462 CDS YP_003103980.1 256380320 8330543 7424894..7425574 1 NC_013093.1 PFAM: peptidase M50; KEGG: ccs:CCNA_03492 transporter; peptidase M50 7425574 8330543 Amir_6332 Actinosynnema mirum DSM 43827 peptidase M50 YP_003103980.1 7424894 D 446462 CDS YP_003103981.1 256380321 8330544 7425600..7426565 1 NC_013093.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); LPPG:FO 2-phospho-L-lactate transferase 7426565 8330544 Amir_6333 Actinosynnema mirum DSM 43827 LPPG:FO 2-phospho-L-lactate transferase YP_003103981.1 7425600 D 446462 CDS YP_003103982.1 256380322 8330545 7426558..7427943 1 NC_013093.1 catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); F420-0--gamma-glutamyl ligase 7427943 8330545 Amir_6334 Actinosynnema mirum DSM 43827 F420-0--gamma-glutamyl ligase YP_003103982.1 7426558 D 446462 CDS YP_003103983.1 256380323 8330546 7427946..7428491 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: sml:Smlt2194 hypothetical protein; NUDIX hydrolase 7428491 8330546 Amir_6335 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003103983.1 7427946 D 446462 CDS YP_003103984.1 256380324 8330547 complement(7428895..7429839) 1 NC_013093.1 KEGG: transcriptional regulator, AraC family; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase-like protein 7429839 8330547 Amir_6336 Actinosynnema mirum DSM 43827 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase-like protein YP_003103984.1 7428895 R 446462 CDS YP_003103985.1 256380325 8330548 complement(7429844..7430923) 1 NC_013093.1 PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: pca:Pcar_2958 mannose-1-phosphate guanyltransferase; Nucleotidyl transferase 7430923 8330548 Amir_6337 Actinosynnema mirum DSM 43827 Nucleotidyl transferase YP_003103985.1 7429844 R 446462 CDS YP_003103986.1 256380326 8330549 7431076..7431465 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7431465 8330549 Amir_6338 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103986.1 7431076 D 446462 CDS YP_003103987.1 256380327 8330550 complement(7431664..7432521) 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: ppg:PputGB1_2720 glycosyl transferase family protein; family 2 glycosyl transferase 7432521 8330550 Amir_6339 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003103987.1 7431664 R 446462 CDS YP_003103988.1 256380328 8330551 complement(7433070..7434203) 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: pfo:Pfl01_5687 glycosyl transferase, group 1; group 1 glycosyl transferase 7434203 8330551 Amir_6340 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003103988.1 7433070 R 446462 CDS YP_003103989.1 256380329 8330552 complement(7434377..7435441) 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: afw:Anae109_1409 glycosyl transferase group 1; group 1 glycosyl transferase 7435441 8330552 Amir_6341 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003103989.1 7434377 R 446462 CDS YP_003103990.1 256380330 8330553 7435587..7436489 1 NC_013093.1 PFAM: glycosyl transferase family 2; KEGG: pzu:PHZ_c3342 glycosyl transferase; family 2 glycosyl transferase 7436489 8330553 Amir_6342 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003103990.1 7435587 D 446462 CDS YP_003103991.1 256380331 8330554 7436521..7436904 1 NC_013093.1 hypothetical protein 7436904 8330554 Amir_6343 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103991.1 7436521 D 446462 CDS YP_003103992.1 256380332 8330555 7437033..7439501 1 NC_013093.1 PFAM: glycosyl transferase family 2; glycosyl transferase group 1; KEGG: dal:Dalk_0014 glycosyl transferase family 2; family 2 glycosyl transferase 7439501 8330555 Amir_6344 Actinosynnema mirum DSM 43827 family 2 glycosyl transferase YP_003103992.1 7437033 D 446462 CDS YP_003103993.1 256380333 8330556 7439494..7440588 1 NC_013093.1 PFAM: glycosyl transferase group 1; KEGG: afw:Anae109_1409 glycosyl transferase group 1; group 1 glycosyl transferase 7440588 8330556 Amir_6345 Actinosynnema mirum DSM 43827 group 1 glycosyl transferase YP_003103993.1 7439494 D 446462 CDS YP_003103994.1 256380334 8330557 complement(7440994..7441884) 1 NC_013093.1 KEGG: gme:Gmet_2472 dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase 7441884 8330557 Amir_6346 Actinosynnema mirum DSM 43827 dTDP-4-dehydrorhamnose reductase YP_003103994.1 7440994 R 446462 CDS YP_003103995.1 256380335 8330558 complement(7441884..7442876) 1 NC_013093.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: dvm:DvMF_0141 dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 7442876 8330558 Amir_6347 Actinosynnema mirum DSM 43827 dTDP-glucose 4,6-dehydratase YP_003103995.1 7441884 R 446462 CDS YP_003103996.1 256380336 8330559 7443051..7444604 1 NC_013093.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bat:BAS5047 LytR family transcription antiterminator; cell envelope-related transcriptional attenuator 7444604 8330559 Amir_6348 Actinosynnema mirum DSM 43827 cell envelope-related transcriptional attenuator YP_003103996.1 7443051 D 446462 CDS YP_003103997.1 256380337 8330560 7444683..7445915 1 NC_013093.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: hypothetical protein; cell envelope-related transcriptional attenuator 7445915 8330560 Amir_6349 Actinosynnema mirum DSM 43827 cell envelope-related transcriptional attenuator YP_003103997.1 7444683 D 446462 CDS YP_003103998.1 256380338 8330561 7445926..7446618 1 NC_013093.1 KEGG: rpd:RPD_3317 AMP-dependent synthetase and ligase; hypothetical protein 7446618 8330561 Amir_6350 Actinosynnema mirum DSM 43827 hypothetical protein YP_003103998.1 7445926 D 446462 CDS YP_003103999.1 256380339 8330562 complement(7446711..7447136) 1 NC_013093.1 PFAM: DoxX family protein; KEGG: aba:Acid345_2953 DoxX; DoxX family protein 7447136 8330562 Amir_6351 Actinosynnema mirum DSM 43827 DoxX family protein YP_003103999.1 7446711 R 446462 CDS YP_003104000.1 256380340 8330563 7447261..7447623 1 NC_013093.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: sme:SM_b20608 transcriptional regulator, ArsR family protein; ArsR family transcriptional regulator 7447623 8330563 Amir_6352 Actinosynnema mirum DSM 43827 ArsR family transcriptional regulator YP_003104000.1 7447261 D 446462 CDS YP_003104001.1 256380341 8330564 7447745..7447957 1 NC_013093.1 hypothetical protein 7447957 8330564 Amir_6353 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104001.1 7447745 D 446462 CDS YP_003104002.1 256380342 8330565 7447954..7448310 1 NC_013093.1 hypothetical protein 7448310 8330565 Amir_6354 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104002.1 7447954 D 446462 CDS YP_003104003.1 256380343 8330567 complement(7448989..7450209) 1 NC_013093.1 SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 7450209 8330567 Amir_6356 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003104003.1 7448989 R 446462 CDS YP_003104004.1 256380344 8330568 7450334..7450567 1 NC_013093.1 hypothetical protein 7450567 8330568 Amir_6357 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104004.1 7450334 D 446462 CDS YP_003104005.1 256380345 8330569 complement(7450681..7451064) 1 NC_013093.1 PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: met:M446_0773 GntR family transcriptional regulator; GntR family transcriptional regulator 7451064 8330569 Amir_6358 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003104005.1 7450681 R 446462 CDS YP_003104006.1 256380346 8330570 7451214..7451645 1 NC_013093.1 hypothetical protein 7451645 8330570 Amir_6359 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104006.1 7451214 D 446462 CDS YP_003104007.1 256380347 8330571 7451658..7451963 1 NC_013093.1 hypothetical protein 7451963 8330571 Amir_6360 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104007.1 7451658 D 446462 CDS YP_003104008.1 256380348 8330572 7452261..7453736 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: pha:PSHAb0091 cell divisionFtsK/SpoIIIE domain-containing protein; cell division protein FtsK/SpoIIIE 7453736 8330572 Amir_6361 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003104008.1 7452261 D 446462 CDS YP_003104009.1 256380349 8330573 7453733..7455400 1 NC_013093.1 hypothetical protein 7455400 8330573 Amir_6362 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104009.1 7453733 D 446462 CDS YP_003104010.1 256380350 8330574 7455414..7455593 1 NC_013093.1 hypothetical protein 7455593 8330574 Amir_6363 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104010.1 7455414 D 446462 CDS YP_003104011.1 256380351 8330575 7455630..7456826 1 NC_013093.1 PFAM: integrase family protein; KEGG: bce:BC1272 DNA integration/recombination/invertion protein; integrase family protein 7456826 8330575 Amir_6364 Actinosynnema mirum DSM 43827 integrase family protein YP_003104011.1 7455630 D 446462 CDS YP_003104012.1 256380352 8330576 complement(7456873..7458351) 1 NC_013093.1 KEGG: dps:DP2013 hypothetical protein; hypothetical protein 7458351 8330576 Amir_6365 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104012.1 7456873 R 446462 CDS YP_003104013.1 256380353 8330577 complement(7458754..7459917) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bcb:BCB4264_A5464 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 7459917 8330577 Amir_6366 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003104013.1 7458754 R 446462 CDS YP_003104014.1 256380354 8330578 complement(7459952..7460473) 1 NC_013093.1 KEGG: predicted protein; K01588 phosphoribosylaminoimidazole carboxylase catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; phosphoribosylaminoimidazole carboxylase, catalytic subunit 7460473 8330578 Amir_6367 Actinosynnema mirum DSM 43827 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_003104014.1 7459952 R 446462 CDS YP_003104015.1 256380355 8330579 complement(7460470..7461660) 1 NC_013093.1 KEGG: hypothetical protein; TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylglycinamide synthetase; phosphoribosylaminoimidazole carboxylase, ATPase subunit 7461660 8330579 Amir_6368 Actinosynnema mirum DSM 43827 phosphoribosylaminoimidazole carboxylase, ATPase subunit YP_003104015.1 7460470 R 446462 CDS YP_003104016.1 256380356 8330580 complement(7461774..7462787) 1 NC_013093.1 hypothetical protein 7462787 8330580 Amir_6369 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104016.1 7461774 R 446462 CDS YP_003104017.1 256380357 8330581 complement(7462784..7463635) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: shw:Sputw3181_4019 ABC transporter; ABC transporter 7463635 8330581 Amir_6370 Actinosynnema mirum DSM 43827 ABC transporter YP_003104017.1 7462784 R 446462 CDS YP_003104018.1 256380358 8330582 complement(7463632..7464015) 1 NC_013093.1 PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sus:Acid_1594 GntR family transcriptional regulator; GntR family transcriptional regulator 7464015 8330582 Amir_6371 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003104018.1 7463632 R 446462 CDS YP_003104019.1 256380359 8330583 complement(7464280..7465503) 1 NC_013093.1 PFAM: hypothetical protein; KEGG: hypothetical protein LOC682657; hypothetical protein 7465503 8330583 Amir_6372 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104019.1 7464280 R 446462 CDS YP_003104020.1 256380360 8330584 7465833..7466693 1 NC_013093.1 hypothetical protein 7466693 8330584 Amir_6373 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104020.1 7465833 D 446462 CDS YP_003104021.1 256380361 8330585 7466686..7466871 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 7466871 8330585 Amir_6374 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104021.1 7466686 D 446462 CDS YP_003104022.1 256380362 8330586 complement(7466991..7467410) 1 NC_013093.1 hypothetical protein 7467410 8330586 Amir_6375 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104022.1 7466991 R 446462 CDS YP_003104023.1 256380363 8330587 complement(7467509..7468306) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7468306 8330587 Amir_6376 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104023.1 7467509 R 446462 CDS YP_003104024.1 256380364 8330588 7468403..7471081 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: MUC17; mucin 17, cell surface associated; ECF subfamily RNA polymerase sigma-24 subunit 7471081 8330588 Amir_6377 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003104024.1 7468403 D 446462 CDS YP_003104025.1 256380365 8330589 7471237..7471791 1 NC_013093.1 PFAM: GtrA family protein; KEGG: GtrA family protein; GtrA family protein 7471791 8330589 Amir_6378 Actinosynnema mirum DSM 43827 GtrA family protein YP_003104025.1 7471237 D 446462 CDS YP_003104026.1 256380366 8330590 complement(7471863..7472705) 1 NC_013093.1 TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: ade:Adeh_1287 histidinol-phosphate phosphatase; histidinol-phosphate phosphatase 7472705 8330590 Amir_6379 Actinosynnema mirum DSM 43827 histidinol-phosphate phosphatase YP_003104026.1 7471863 R 446462 CDS YP_003104027.1 256380367 8330591 7472738..7473409 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: mxa:MXAN_5313 DNA-binding response regulator; winged helix family two component transcriptional regulator 7473409 8330591 Amir_6380 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003104027.1 7472738 D 446462 CDS YP_003104028.1 256380368 8330592 7473409..7474683 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ade:Adeh_2915 periplasmic sensor signal transduction histidine kinase; histidine kinase 7474683 8330592 Amir_6381 Actinosynnema mirum DSM 43827 histidine kinase YP_003104028.1 7473409 D 446462 CDS YP_003104029.1 256380369 8330593 complement(7475478..7475918) 1 NC_013093.1 KEGG: predicted gene, 100042292; hypothetical protein 7475918 8330593 Amir_6382 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104029.1 7475478 R 446462 CDS YP_003104030.1 256380370 8330594 complement(7475915..7478260) 1 NC_013093.1 KEGG: Hypothetical protein CBG02561; hypothetical protein 7478260 8330594 Amir_6383 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104030.1 7475915 R 446462 CDS YP_003104031.1 256380371 8330595 7478283..7479902 1 NC_013093.1 KEGG: ade:Adeh_1681 PE-PGRS family protein; PE-PGRS family protein 7479902 8330595 Amir_6384 Actinosynnema mirum DSM 43827 PE-PGRS family protein YP_003104031.1 7478283 D 446462 CDS YP_003104032.1 256380372 8330596 complement(7479854..7480162) 1 NC_013093.1 hypothetical protein 7480162 8330596 Amir_6385 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104032.1 7479854 R 446462 CDS YP_003104033.1 256380373 8330597 complement(7480159..7480650) 1 NC_013093.1 hypothetical protein 7480650 8330597 Amir_6386 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104033.1 7480159 R 446462 CDS YP_003104034.1 256380374 8330598 complement(7480806..7481735) 1 NC_013093.1 PFAM: pyruvate carboxyltransferase; KEGG: rce:RC1_0377 3-hydroxy-3-methylglutaryl-CoA lyase; pyruvate carboxyltransferase 7481735 8330598 Amir_6387 Actinosynnema mirum DSM 43827 pyruvate carboxyltransferase YP_003104034.1 7480806 R 446462 CDS YP_003104035.1 256380375 8330599 complement(7482054..7482566) 1 NC_013093.1 PFAM: membrane-flanked domain; KEGG: kpe:KPK_2129 hypothetical protein; membrane-flanked domain-containing protein 7482566 8330599 Amir_6388 Actinosynnema mirum DSM 43827 membrane-flanked domain-containing protein YP_003104035.1 7482054 R 446462 CDS YP_003104036.1 256380376 8330600 complement(7482599..7483360) 1 NC_013093.1 TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; KEGG: ade:Adeh_2388 biotin--acetyl-CoA-carboxylase ligase; biotin/acetyl-CoA-carboxylase ligase 7483360 8330600 Amir_6389 Actinosynnema mirum DSM 43827 biotin/acetyl-CoA-carboxylase ligase YP_003104036.1 7482599 R 446462 CDS YP_003104037.1 256380377 8330601 7483647..7485278 1 NC_013093.1 PFAM: carboxyl transferase; KEGG: sus:Acid_1492 carboxyl transferase; carboxyl transferase 7485278 8330601 Amir_6390 Actinosynnema mirum DSM 43827 carboxyl transferase YP_003104037.1 7483647 D 446462 CDS YP_003104038.1 256380378 8330602 7485275..7485496 1 NC_013093.1 hypothetical protein 7485496 8330602 Amir_6391 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104038.1 7485275 D 446462 CDS YP_003104039.1 256380379 8330603 complement(7485509..7485913) 1 NC_013093.1 hypothetical protein 7485913 8330603 Amir_6392 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104039.1 7485509 R 446462 CDS YP_003104040.1 256380380 8330604 7486664..7487284 1 NC_013093.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 7487284 8330604 Amir_6393 Actinosynnema mirum DSM 43827 Maf-like protein YP_003104040.1 7486664 D 446462 CDS YP_003104041.1 256380381 8330605 7487724..7489064 1 NC_013093.1 PFAM: sodium:dicarboxylate symporter; KEGG: mes:Meso_3163 sodium:dicarboxylate symporter; sodium:dicarboxylate symporter 7489064 8330605 Amir_6394 Actinosynnema mirum DSM 43827 sodium:dicarboxylate symporter YP_003104041.1 7487724 D 446462 CDS YP_003104042.1 256380382 8330606 complement(7489135..7489833) 1 NC_013093.1 hypothetical protein 7489833 8330606 Amir_6395 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104042.1 7489135 R 446462 CDS YP_003104043.1 256380383 8330607 7489992..7491758 1 NC_013093.1 PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: biotin carboxylase; K01946 biotin carboxylase; carbamoyl-phosphate synthase L chain ATP- binding 7491758 8330607 Amir_6396 Actinosynnema mirum DSM 43827 carbamoyl-phosphate synthase L chain ATP- binding YP_003104043.1 7489992 D 446462 CDS YP_003104044.1 256380384 8330608 7491768..7492154 1 NC_013093.1 PFAM: protein of unknown function DUF1707; hypothetical protein 7492154 8330608 Amir_6397 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104044.1 7491768 D 446462 CDS YP_003104045.1 256380385 8330609 7492151..7493026 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bja:bll1358 hydrolase; HAD superfamily hydrolase 7493026 8330609 Amir_6398 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003104045.1 7492151 D 446462 CDS YP_003104046.1 256380386 8330610 7493195..7493788 1 NC_013093.1 hypothetical protein 7493788 8330610 Amir_6399 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104046.1 7493195 D 446462 CDS YP_003104047.1 256380387 8330611 7493880..7494260 1 NC_013093.1 hypothetical protein 7494260 8330611 Amir_6400 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104047.1 7493880 D 446462 CDS YP_003104048.1 256380388 8330612 7494287..7495552 1 NC_013093.1 KEGG: mgm:Mmc1_2179 outer membrane adhesin like proteiin; hypothetical protein 7495552 8330612 Amir_6401 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104048.1 7494287 D 446462 CDS YP_003104049.1 256380389 8330613 7495549..7496355 1 NC_013093.1 hypothetical protein 7496355 8330613 Amir_6402 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104049.1 7495549 D 446462 CDS YP_003104050.1 256380390 8330614 complement(7496622..7497083) 1 NC_013093.1 PFAM: AIG2 family protein; KEGG: mpo:Mpop_3184 AIG2 family protein; AIG2 family protein 7497083 8330614 Amir_6403 Actinosynnema mirum DSM 43827 AIG2 family protein YP_003104050.1 7496622 R 446462 CDS YP_003104051.1 256380391 8330615 7497229..7498632 1 NC_013093.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase 7498632 8330615 Amir_6404 Actinosynnema mirum DSM 43827 flavoprotein disulfide reductase YP_003104051.1 7497229 D 446462 CDS YP_003104052.1 256380392 8330616 complement(7499068..7499745) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 7499745 8330616 Amir_6405 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003104052.1 7499068 R 446462 CDS YP_003104053.1 256380393 8330617 complement(7499742..7500923) 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 7500923 8330617 Amir_6406 Actinosynnema mirum DSM 43827 histidine kinase YP_003104053.1 7499742 R 446462 CDS YP_003104054.1 256380394 8330618 7501129..7502058 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mmr:Mmar10_1823 ABC transporter; ABC transporter 7502058 8330618 Amir_6407 Actinosynnema mirum DSM 43827 ABC transporter YP_003104054.1 7501129 D 446462 CDS YP_003104055.1 256380395 8330619 7502058..7502921 1 NC_013093.1 KEGG: cak:Caul_1641 hypothetical protein; hypothetical protein 7502921 8330619 Amir_6408 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104055.1 7502058 D 446462 CDS YP_003104056.1 256380396 8330620 complement(7502977..7504491) 1 NC_013093.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: azc:AZC_2710 glycerol kinase; glycerol kinase 7504491 8330620 Amir_6409 Actinosynnema mirum DSM 43827 glycerol kinase YP_003104056.1 7502977 R 446462 CDS YP_003104057.1 256380397 8330621 complement(7504523..7505263) 1 NC_013093.1 PFAM: major intrinsic protein; KEGG: pha:PSHAb0552 glycerol diffusion channel; major intrinsic protein 7505263 8330621 Amir_6410 Actinosynnema mirum DSM 43827 major intrinsic protein YP_003104057.1 7504523 R 446462 CDS YP_003104058.1 256380398 8330622 7505482..7507221 1 NC_013093.1 PFAM: FAD dependent oxidoreductase; monooxygenase FAD-binding; KEGG: vei:Veis_2018 FAD dependent oxidoreductase; FAD dependent oxidoreductase 7507221 8330622 Amir_6411 Actinosynnema mirum DSM 43827 FAD dependent oxidoreductase YP_003104058.1 7505482 D 446462 CDS YP_003104059.1 256380399 8330623 7507398..7508255 1 NC_013093.1 KEGG: rpa:RPA3963 hypothetical protein; hypothetical protein 7508255 8330623 Amir_6412 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104059.1 7507398 D 446462 CDS YP_003104060.1 256380400 8330624 7508426..7508851 1 NC_013093.1 hypothetical protein 7508851 8330624 Amir_6413 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104060.1 7508426 D 446462 CDS YP_003104061.1 256380401 8330625 complement(7508949..7510220) 1 NC_013093.1 KEGG: acr:Acry_1887 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; amidohydrolase 7510220 8330625 Amir_6414 Actinosynnema mirum DSM 43827 amidohydrolase YP_003104061.1 7508949 R 446462 CDS YP_003104062.1 256380402 8330626 complement(7510217..7511392) 1 NC_013093.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: pla:Plav_2614 amidohydrolase; amidohydrolase 7511392 8330626 Amir_6415 Actinosynnema mirum DSM 43827 amidohydrolase YP_003104062.1 7510217 R 446462 CDS YP_003104063.1 256380403 8330627 complement(7511743..7512081) 1 NC_013093.1 KEGG: GL26851 gene product from transcript GL26851- RA; hypothetical protein 7512081 8330627 Amir_6416 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104063.1 7511743 R 446462 CDS YP_003104064.1 256380404 8330628 complement(7512148..7513134) 1 NC_013093.1 TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: rru:Rru_A2478 arginine/ornithine transport system ATPase; LAO/AO transport system ATPase 7513134 8330628 Amir_6417 Actinosynnema mirum DSM 43827 LAO/AO transport system ATPase YP_003104064.1 7512148 R 446462 CDS YP_003104065.1 256380405 8330629 complement(7513127..7515316) 1 NC_013093.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 7515316 8330629 Amir_6418 Actinosynnema mirum DSM 43827 methylmalonyl-CoA mutase YP_003104065.1 7513127 R 446462 CDS YP_003104066.1 256380406 8330630 complement(7515313..7517094) 1 NC_013093.1 PFAM: methylmalonyl-CoA mutase; KEGG: rru:Rru_A2480 methylmalonyl-CoA mutase; methylmalonyl-CoA mutase 7517094 8330630 Amir_6419 Actinosynnema mirum DSM 43827 methylmalonyl-CoA mutase YP_003104066.1 7515313 R 446462 CDS YP_003104067.1 256380407 8330631 7517538..7519355 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: pau:PA14_00875 serine/threonine protein kinase PpkA; serine/threonine protein kinase 7519355 8330631 Amir_6420 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003104067.1 7517538 D 446462 CDS YP_003104068.1 256380408 8330632 7519395..7520207 1 NC_013093.1 TIGRFAM: purine nucleotide phosphorylase; inosine guanosine and xanthosine phosphorylase family; PFAM: purine or other phosphorylase family 1; KEGG: scl:sce5862 hypothetical protein; purine nucleotide phosphorylase 7520207 8330632 Amir_6421 Actinosynnema mirum DSM 43827 purine nucleotide phosphorylase YP_003104068.1 7519395 D 446462 CDS YP_003104069.1 256380409 8330633 7520204..7521832 1 NC_013093.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: scl:sce4837 phosphoglucomutase/phosphomannomutase; phosphomannomutase 7521832 8330633 Amir_6422 Actinosynnema mirum DSM 43827 phosphomannomutase YP_003104069.1 7520204 D 446462 CDS YP_003104070.1 256380410 8330634 complement(7521867..7522190) 1 NC_013093.1 hypothetical protein 7522190 8330634 Amir_6423 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104070.1 7521867 R 446462 CDS YP_003104071.1 256380411 8330635 complement(7522246..7522575) 1 NC_013093.1 KEGG: acp:A2cp1_4175 general secretory system II protein E domain protein; hypothetical protein 7522575 8330635 Amir_6424 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104071.1 7522246 R 446462 CDS YP_003104072.1 256380412 8330636 complement(7522875..7523270) 1 NC_013093.1 PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; KEGG: mag:amb3964 transcriptional regulator; MerR family transcriptional regulator 7523270 8330636 Amir_6425 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003104072.1 7522875 R 446462 CDS YP_003104073.1 256380413 8330637 complement(7523386..7523769) 1 NC_013093.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: acp:A2cp1_3061 death-on-curing family protein; filamentation induced by cAMP protein Fic 7523769 8330637 Amir_6426 Actinosynnema mirum DSM 43827 filamentation induced by cAMP protein Fic YP_003104073.1 7523386 R 446462 CDS YP_003104074.1 256380414 8330638 complement(7523810..7524010) 1 NC_013093.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: tgr:Tgr7_2434 CopG domain protein DNA-binding domain protein; CopG domain-containing protein DNA-binding domain-containing protein 7524010 8330638 Amir_6427 Actinosynnema mirum DSM 43827 CopG domain-containing protein DNA-binding domain-containing protein YP_003104074.1 7523810 R 446462 CDS YP_003104075.1 256380415 8330639 7524033..7524686 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: pla:Plav_2655 TetR family transcriptional regulator; TetR family transcriptional regulator 7524686 8330639 Amir_6428 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104075.1 7524033 D 446462 CDS YP_003104076.1 256380416 8330640 complement(7525128..7525751) 1 NC_013093.1 TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: rde:RD1_3976 uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 7525751 8330640 Amir_6429 Actinosynnema mirum DSM 43827 uracil phosphoribosyltransferase YP_003104076.1 7525128 R 446462 CDS YP_003104077.1 256380417 8330641 7525948..7528944 1 NC_013093.1 PFAM: pentapeptide repeat protein; KEGG: scl:sce3623 hypothetical protein; pentapeptide repeat-containing protein 7528944 8330641 Amir_6430 Actinosynnema mirum DSM 43827 pentapeptide repeat-containing protein YP_003104077.1 7525948 D 446462 CDS YP_003104078.1 256380418 8330642 7529075..7534375 1 NC_013093.1 PFAM: hypothetical protein; pentapeptide repeat protein; SMART: hypothetical protein; KEGG: scl:sce3623 hypothetical protein; hypothetical protein 7534375 8330642 Amir_6431 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104078.1 7529075 D 446462 CDS YP_003104079.1 256380419 8330643 7534379..7535362 1 NC_013093.1 PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: hypothetical protein; oxidoreductase domain-containing protein 7535362 8330643 Amir_6432 Actinosynnema mirum DSM 43827 oxidoreductase domain-containing protein YP_003104079.1 7534379 D 446462 CDS YP_003104080.1 256380420 8330644 complement(7535359..7535610) 1 NC_013093.1 hypothetical protein 7535610 8330644 Amir_6433 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104080.1 7535359 R 446462 CDS YP_003104081.1 256380421 8330645 7535679..7536518 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: met:M446_4768 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 7536518 8330645 Amir_6434 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003104081.1 7535679 D 446462 CDS YP_003104082.1 256380422 8330646 7536532..7536705 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 7536705 8330646 Amir_6435 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104082.1 7536532 D 446462 CDS YP_003104083.1 256380423 8330647 7536751..7537407 1 NC_013093.1 PFAM: protein of unknown function DUF1707; KEGG: pha:PSHAa0324 hypothetical protein; hypothetical protein 7537407 8330647 Amir_6436 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104083.1 7536751 D 446462 CDS YP_003104084.1 256380424 8330648 complement(7537472..7539619) 1 NC_013093.1 PFAM: NB-ARC domain protein; KEGG: scl:sce6858 hypothetical protein; NB-ARC domain-containing protein 7539619 8330648 Amir_6437 Actinosynnema mirum DSM 43827 NB-ARC domain-containing protein YP_003104084.1 7537472 R 446462 CDS YP_003104085.1 256380425 8330649 complement(7539624..7540136) 1 NC_013093.1 hypothetical protein 7540136 8330649 Amir_6438 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104085.1 7539624 R 446462 CDS YP_003104086.1 256380426 8330650 complement(7540111..7540347) 1 NC_013093.1 hypothetical protein 7540347 8330650 Amir_6439 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104086.1 7540111 R 446462 CDS YP_003104087.1 256380427 8330651 complement(7540530..7540958) 1 NC_013093.1 hypothetical protein 7540958 8330651 Amir_6440 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104087.1 7540530 R 446462 CDS YP_003104088.1 256380428 8330652 7541203..7541526 1 NC_013093.1 hypothetical protein 7541526 8330652 Amir_6441 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104088.1 7541203 D 446462 CDS YP_003104089.1 256380429 8330653 7541532..7542710 1 NC_013093.1 PFAM: NLP/P60 protein; KEGG: bpt:Bpet2252 hypothetical protein; NLP/P60 protein 7542710 8330653 Amir_6442 Actinosynnema mirum DSM 43827 NLP/P60 protein YP_003104089.1 7541532 D 446462 CDS YP_003104090.1 256380430 8330654 7542715..7543089 1 NC_013093.1 hypothetical protein 7543089 8330654 Amir_6443 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104090.1 7542715 D 446462 CDS YP_003104091.1 256380431 8330655 7543086..7545728 1 NC_013093.1 KEGG: mgm:Mmc1_2162 hypothetical protein; Chromosome segregation ATPase-like protein 7545728 8330655 Amir_6444 Actinosynnema mirum DSM 43827 Chromosome segregation ATPase-like protein YP_003104091.1 7543086 D 446462 CDS YP_003104092.1 256380432 8330656 7545811..7547025 1 NC_013093.1 hypothetical protein 7547025 8330656 Amir_6445 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104092.1 7545811 D 446462 CDS YP_003104093.1 256380433 8330657 complement(7547102..7548172) 1 NC_013093.1 KEGG: afw:Anae109_0100 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; adenosine deaminase 7548172 8330657 Amir_6446 Actinosynnema mirum DSM 43827 adenosine deaminase YP_003104093.1 7547102 R 446462 CDS YP_003104094.1 256380434 8330658 7548446..7549672 1 NC_013093.1 KEGG: CG33251; hypothetical protein 7549672 8330658 Amir_6447 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104094.1 7548446 D 446462 CDS YP_003104095.1 256380435 8330659 7550003..7550587 1 NC_013093.1 hypothetical protein 7550587 8330659 Amir_6448 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104095.1 7550003 D 446462 CDS YP_003104096.1 256380436 8330660 complement(7550646..7551920) 1 NC_013093.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 7551920 deoA 8330660 deoA Actinosynnema mirum DSM 43827 thymidine phosphorylase YP_003104096.1 7550646 R 446462 CDS YP_003104097.1 256380437 8330661 complement(7551917..7552360) 1 NC_013093.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: nar:Saro_0145 cytidine deaminase; zinc-binding CMP/dCMP deaminase 7552360 8330661 Amir_6450 Actinosynnema mirum DSM 43827 zinc-binding CMP/dCMP deaminase YP_003104097.1 7551917 R 446462 CDS YP_003104098.1 256380438 8330662 complement(7552353..7553618) 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: bcz:BCZK3548 ABC transporter, permease; inner-membrane translocator 7553618 8330662 Amir_6451 Actinosynnema mirum DSM 43827 inner-membrane translocator YP_003104098.1 7552353 R 446462 CDS YP_003104099.1 256380439 8330663 complement(7553615..7554688) 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: scl:sce7757 ABC transporter permease; inner-membrane translocator 7554688 8330663 Amir_6452 Actinosynnema mirum DSM 43827 inner-membrane translocator YP_003104099.1 7553615 R 446462 CDS YP_003104100.1 256380440 8330664 complement(7554688..7556232) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce7755 sugar ABC transporter, ATP- binding protein; ABC transporter 7556232 8330664 Amir_6453 Actinosynnema mirum DSM 43827 ABC transporter YP_003104100.1 7554688 R 446462 CDS YP_003104101.1 256380441 8330665 complement(7556303..7557451) 1 NC_013093.1 PFAM: basic membrane lipoprotein; KEGG: smd:Smed_3416 basic membrane lipoprotein; basic membrane lipoprotein 7557451 8330665 Amir_6454 Actinosynnema mirum DSM 43827 basic membrane lipoprotein YP_003104101.1 7556303 R 446462 CDS YP_003104102.1 256380442 8330666 7557993..7558517 1 NC_013093.1 KEGG: avhD4; conjugative coupling protein; K03205 type IV secretion system protein VirD4; hypothetical protein 7558517 8330666 Amir_6455 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104102.1 7557993 D 446462 CDS YP_003104103.1 256380443 8330667 7558574..7560247 1 NC_013093.1 KEGG: mucin-associated surface protein (MASP); hypothetical protein 7560247 8330667 Amir_6456 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104103.1 7558574 D 446462 CDS YP_003104104.1 256380444 8330668 complement(7560273..7565210) 1 NC_013093.1 KEGG: eln1; tropoelastin 1; hypothetical protein 7565210 8330668 Amir_6457 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104104.1 7560273 R 446462 CDS YP_003104105.1 256380445 8330669 7565242..7593831 1 NC_013093.1 KEGG: Muc19; mucin 19; hypothetical protein 7593831 8330669 Amir_6458 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104105.1 7565242 D 446462 CDS YP_003104106.1 256380446 8330670 7593828..7595096 1 NC_013093.1 hypothetical protein 7595096 8330670 Amir_6459 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104106.1 7593828 D 446462 CDS YP_003104107.1 256380447 8330671 complement(7595549..7595839) 1 NC_013093.1 KEGG: GK19428 gene product from transcript GK19428- RA; hypothetical protein 7595839 8330671 Amir_6460 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104107.1 7595549 R 446462 CDS YP_003104108.1 256380448 8330672 7595856..7599962 1 NC_013093.1 KEGG: ank:AnaeK_3854 tetratricopeptide TPR_2 repeat protein; hypothetical protein 7599962 8330672 Amir_6461 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104108.1 7595856 D 446462 CDS YP_003104109.1 256380449 8330673 7600183..7600605 1 NC_013093.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: jan:Jann_3968 succinate dehydrogenase subunit C; succinate dehydrogenase, cytochrome b556 subunit 7600605 8330673 Amir_6462 Actinosynnema mirum DSM 43827 succinate dehydrogenase, cytochrome b556 subunit YP_003104109.1 7600183 D 446462 CDS YP_003104110.1 256380450 8330674 7600608..7601024 1 NC_013093.1 KEGG: eta:ETA_23070 succinate dehydrogenase hydrophobic membrane anchor protein; Succinate dehydrogenase hydrophobic anchor subunit-like protein 7601024 8330674 Amir_6463 Actinosynnema mirum DSM 43827 Succinate dehydrogenase hydrophobic anchor subunit-like protein YP_003104110.1 7600608 D 446462 CDS YP_003104111.1 256380451 8330675 7601047..7602798 1 NC_013093.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 7602798 sdhA 8330675 sdhA Actinosynnema mirum DSM 43827 succinate dehydrogenase flavoprotein subunit YP_003104111.1 7601047 D 446462 CDS YP_003104112.1 256380452 8330676 7602798..7603580 1 NC_013093.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 7603580 sdhB 8330676 sdhB Actinosynnema mirum DSM 43827 succinate dehydrogenase iron-sulfur subunit YP_003104112.1 7602798 D 446462 CDS YP_003104113.1 256380453 8330677 complement(7603854..7605863) 1 NC_013093.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: rpc:RPC_4073 serine-type D-Ala-D-Ala carboxypeptidase; Serine-type D-Ala-D-Ala carboxypeptidase 7605863 8330677 Amir_6466 Actinosynnema mirum DSM 43827 Serine-type D-Ala-D-Ala carboxypeptidase YP_003104113.1 7603854 R 446462 CDS YP_003104114.1 256380454 8330678 7605963..7606190 1 NC_013093.1 hypothetical protein 7606190 8330678 Amir_6467 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104114.1 7605963 D 446462 CDS YP_003104115.1 256380455 8330679 7606219..7606566 1 NC_013093.1 hypothetical protein 7606566 8330679 Amir_6468 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104115.1 7606219 D 446462 CDS YP_003104116.1 256380456 8330680 complement(7606724..7607743) 1 NC_013093.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: ypb:YPTS_4040 ribonuclease; ribonuclease 7607743 8330680 Amir_6469 Actinosynnema mirum DSM 43827 ribonuclease YP_003104116.1 7606724 R 446462 CDS YP_003104117.1 256380457 8330681 complement(7607878..7608897) 1 NC_013093.1 KEGG: aha:AHA_3183 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; tryptophanyl-tRNA synthetase 7608897 8330681 Amir_6470 Actinosynnema mirum DSM 43827 tryptophanyl-tRNA synthetase YP_003104117.1 7607878 R 446462 CDS YP_003104118.1 256380458 8330682 complement(7608919..7609221) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7609221 8330682 Amir_6471 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104118.1 7608919 R 446462 CDS YP_003104119.1 256380459 8330683 complement(7609384..7611900) 1 NC_013093.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; FO synthase 7611900 fbiC 8330683 fbiC Actinosynnema mirum DSM 43827 FO synthase YP_003104119.1 7609384 R 446462 CDS YP_003104120.1 256380460 8330684 complement(7612047..7612325) 1 NC_013093.1 PFAM: protein of unknown function DUF86; KEGG: azo:azo0145 hypothetical protein; hypothetical protein 7612325 8330684 Amir_6473 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104120.1 7612047 R 446462 CDS YP_003104121.1 256380461 8330685 complement(7612315..7612623) 1 NC_013093.1 PFAM: DNA polymerase beta domain protein region; KEGG: aba:Acid345_1968 nucleotidyltransferase; DNA polymerase beta domain-containing protein 7612623 8330685 Amir_6474 Actinosynnema mirum DSM 43827 DNA polymerase beta domain-containing protein YP_003104121.1 7612315 R 446462 CDS YP_003104122.1 256380462 8330686 complement(7612665..7613459) 1 NC_013093.1 KEGG: nma:NMA0348 nuclease; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: endonuclease/exonuclease/phosphatase; exodeoxyribonuclease III Xth 7613459 8330686 Amir_6475 Actinosynnema mirum DSM 43827 exodeoxyribonuclease III Xth YP_003104122.1 7612665 R 446462 CDS YP_003104123.1 256380463 8330687 complement(7613469..7613684) 1 NC_013093.1 hypothetical protein 7613684 8330687 Amir_6476 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104123.1 7613469 R 446462 CDS YP_003104124.1 256380464 8330688 complement(7613740..7614066) 1 NC_013093.1 hypothetical protein 7614066 8330688 Amir_6477 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104124.1 7613740 R 446462 CDS YP_003104125.1 256380465 8330689 complement(7614279..7615499) 1 NC_013093.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 7615499 8330689 Amir_6478 Actinosynnema mirum DSM 43827 isocitrate dehydrogenase YP_003104125.1 7614279 R 446462 CDS YP_003104126.1 256380466 8330690 7615639..7616445 1 NC_013093.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: mag:amb4172 membrane-bound metal-dependent hydrolase; membrane-bound metal-dependent hydrolase 7616445 8330690 Amir_6479 Actinosynnema mirum DSM 43827 membrane-bound metal-dependent hydrolase YP_003104126.1 7615639 D 446462 CDS YP_003104127.1 256380467 8330691 7616546..7617025 1 NC_013093.1 hypothetical protein 7617025 8330691 Amir_6480 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104127.1 7616546 D 446462 CDS YP_003104128.1 256380468 8330693 7617236..7618387 1 NC_013093.1 PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: rle:pRL110201 chaperone; heat shock protein DnaJ domain-containing protein 7618387 8330693 Amir_6481 Actinosynnema mirum DSM 43827 heat shock protein DnaJ domain-containing protein YP_003104128.1 7617236 D 446462 CDS YP_003104129.1 256380469 8330694 7618413..7620188 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_2255 serine/threonine protein kinase; serine/threonine protein kinase 7620188 8330694 Amir_6482 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003104129.1 7618413 D 446462 CDS YP_003104130.1 256380470 8330695 7620268..7620465 1 NC_013093.1 hypothetical protein 7620465 8330695 Amir_6483 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104130.1 7620268 D 446462 CDS YP_003104131.1 256380471 8330696 7620462..7620893 1 NC_013093.1 hypothetical protein 7620893 8330696 Amir_6484 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104131.1 7620462 D 446462 CDS YP_003104132.1 256380472 8330697 7621198..7621983 1 NC_013093.1 KEGG: reu:Reut_A1068 ABC transporter permease protein; ABC transporter permease 7621983 8330697 Amir_6485 Actinosynnema mirum DSM 43827 ABC transporter permease YP_003104132.1 7621198 D 446462 CDS YP_003104133.1 256380473 8330698 7621976..7622773 1 NC_013093.1 PFAM: protein of unknown function DUF990; KEGG: aav:Aave_2071 protein of unknown function DUF990; hypothetical protein 7622773 8330698 Amir_6486 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104133.1 7621976 D 446462 CDS YP_003104134.1 256380474 8330699 7622770..7623723 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6750 ABC transporter, ATP-binding protein; ABC transporter 7623723 8330699 Amir_6487 Actinosynnema mirum DSM 43827 ABC transporter YP_003104134.1 7622770 D 446462 CDS YP_003104135.1 256380475 8330700 7623763..7624158 1 NC_013093.1 hypothetical protein 7624158 8330700 Amir_6488 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104135.1 7623763 D 446462 CDS YP_003104136.1 256380476 8330701 7624265..7624456 1 NC_013093.1 PFAM: Domain of unknown function DUF1918; hypothetical protein 7624456 8330701 Amir_6489 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104136.1 7624265 D 446462 CDS YP_003104137.1 256380477 8330702 complement(7624453..7625184) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mes:Meso_0701 transcriptional regulator, TetR family; TetR family transcriptional regulator 7625184 8330702 Amir_6490 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104137.1 7624453 R 446462 CDS YP_003104138.1 256380478 8330703 complement(7625682..7626476) 1 NC_013093.1 PFAM: inositol monophosphatase; KEGG: mes:Meso_2748 histidinol-phosphate phosphatase; inositol monophosphatase 7626476 8330703 Amir_6491 Actinosynnema mirum DSM 43827 inositol monophosphatase YP_003104138.1 7625682 R 446462 CDS YP_003104139.1 256380479 8330704 complement(7626582..7627571) 1 NC_013093.1 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 7627571 8330704 Amir_6492 Actinosynnema mirum DSM 43827 malate dehydrogenase YP_003104139.1 7626582 R 446462 CDS YP_003104140.1 256380480 8330705 7627731..7628345 1 NC_013093.1 PFAM: pentapeptide repeat protein; KEGG: bca:BCE_1946 hypothetical protein; pentapeptide repeat-containing protein 7628345 8330705 Amir_6493 Actinosynnema mirum DSM 43827 pentapeptide repeat-containing protein YP_003104140.1 7627731 D 446462 CDS YP_003104141.1 256380481 8330706 complement(7628404..7632021) 1 NC_013093.1 KEGG: mgm:Mmc1_1473 conserved hypothetical protein, conserved; hypothetical protein 7632021 8330706 Amir_6494 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104141.1 7628404 R 446462 CDS YP_003104142.1 256380482 8330707 complement(7632103..7633626) 1 NC_013093.1 KEGG: mag:amb0236 hypothetical protein; hypothetical protein 7633626 8330707 Amir_6495 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104142.1 7632103 R 446462 CDS YP_003104143.1 256380483 8330708 complement(7633623..7634093) 1 NC_013093.1 hypothetical protein 7634093 8330708 Amir_6496 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104143.1 7633623 R 446462 CDS YP_003104144.1 256380484 8330709 7634285..7635277 1 NC_013093.1 PFAM: protein of unknown function DUF606; KEGG: pmr:PMI1526 hypothetical protein; hypothetical protein 7635277 8330709 Amir_6497 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104144.1 7634285 D 446462 CDS YP_003104145.1 256380485 8330710 7635285..7636151 1 NC_013093.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: pca:Pcar_2461 methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; methenyltetrahydrofolate cyclohydrolase 7636151 8330710 Amir_6498 Actinosynnema mirum DSM 43827 methenyltetrahydrofolate cyclohydrolase YP_003104145.1 7635285 D 446462 CDS YP_003104146.1 256380486 8330711 7636172..7636471 1 NC_013093.1 hypothetical protein 7636471 8330711 Amir_6499 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104146.1 7636172 D 446462 CDS YP_003104147.1 256380487 8330712 complement(7636708..7636863) 1 NC_013093.1 hypothetical protein 7636863 8330712 Amir_6500 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104147.1 7636708 R 446462 CDS YP_003104148.1 256380488 8330714 7637872..7638678 1 NC_013093.1 KEGG: hypothetical LOC792361; hypothetical protein 7638678 8330714 Amir_6502 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104148.1 7637872 D 446462 CDS YP_003104149.1 256380489 8330715 complement(7638927..7640498) 1 NC_013093.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 7640498 purH 8330715 purH Actinosynnema mirum DSM 43827 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_003104149.1 7638927 R 446462 CDS YP_003104150.1 256380490 8330716 complement(7640495..7641130) 1 NC_013093.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 7641130 purN 8330716 purN Actinosynnema mirum DSM 43827 phosphoribosylglycinamide formyltransferase YP_003104150.1 7640495 R 446462 CDS YP_003104151.1 256380491 8330717 complement(7641281..7643146) 1 NC_013093.1 KEGG: hypothetical protein LOC690456; ATPase AAA 7643146 8330717 Amir_6505 Actinosynnema mirum DSM 43827 ATPase AAA YP_003104151.1 7641281 R 446462 CDS YP_003104152.1 256380492 8330718 complement(7643262..7643963) 1 NC_013093.1 KEGG: similar to AGAP004367-PA; hypothetical protein 7643963 8330718 Amir_6506 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104152.1 7643262 R 446462 CDS YP_003104153.1 256380493 8330719 complement(7644147..7645037) 1 NC_013093.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 7645037 8330719 Amir_6507 Actinosynnema mirum DSM 43827 succinyl-CoA synthetase subunit alpha YP_003104153.1 7644147 R 446462 CDS YP_003104154.1 256380494 8330720 complement(7645043..7646212) 1 NC_013093.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 7646212 sucC 8330720 sucC Actinosynnema mirum DSM 43827 succinyl-CoA synthetase subunit beta YP_003104154.1 7645043 R 446462 CDS YP_003104155.1 256380495 8330721 complement(7646449..7648011) 1 NC_013093.1 KEGG: mpo:Mpop_4712 hypothetical protein; hypothetical protein 7648011 8330721 Amir_6509 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104155.1 7646449 R 446462 CDS YP_003104156.1 256380496 8330722 complement(7648571..7649452) 1 NC_013093.1 KEGG: bpm:BURPS1710b_2554 hypothetical protein; hypothetical protein 7649452 8330722 Amir_6510 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104156.1 7648571 R 446462 CDS YP_003104157.1 256380497 8330723 7650110..7650784 1 NC_013093.1 PFAM: peptidase M23; KEGG: peptidase M23B; peptidase M23 7650784 8330723 Amir_6511 Actinosynnema mirum DSM 43827 peptidase M23 YP_003104157.1 7650110 D 446462 CDS YP_003104158.1 256380498 8330724 complement(7650759..7651124) 1 NC_013093.1 hypothetical protein 7651124 8330724 Amir_6512 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104158.1 7650759 R 446462 CDS YP_003104159.1 256380499 8330725 complement(7651764..7654109) 1 NC_013093.1 TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase; ATP-dependent DNA helicase PcrA 7654109 8330725 Amir_6513 Actinosynnema mirum DSM 43827 ATP-dependent DNA helicase PcrA YP_003104159.1 7651764 R 446462 CDS YP_003104160.1 256380500 8330726 7654346..7654636 1 NC_013093.1 TIGRFAM: chorismate mutase; KEGG: cha:CHAB381_1299 chorismate mutase/prephenate dehydratase; chorismate mutase 7654636 8330726 Amir_6514 Actinosynnema mirum DSM 43827 chorismate mutase YP_003104160.1 7654346 D 446462 CDS YP_003104161.1 256380501 8330727 complement(7654778..7655842) 1 NC_013093.1 PFAM: histone deacetylase superfamily; KEGG: HDA08; HDA08 (histone deacetylase 8); histone deacetylase; histone deacetylase superfamily 7655842 8330727 Amir_6515 Actinosynnema mirum DSM 43827 histone deacetylase superfamily YP_003104161.1 7654778 R 446462 CDS YP_003104162.1 256380502 8330728 7655913..7656230 1 NC_013093.1 KEGG: gbm:Gbem_3934 protein of unknown function DUF6 transmembrane; hypothetical protein 7656230 8330728 Amir_6516 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104162.1 7655913 D 446462 CDS YP_003104163.1 256380503 8330729 7656333..7657271 1 NC_013093.1 KEGG: Taf4a; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor; K03129 transcription initiation factor TFIID subunit D3; hypothetical protein 7657271 8330729 Amir_6517 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104163.1 7656333 D 446462 CDS YP_003104164.1 256380504 8330730 7657458..7658285 1 NC_013093.1 hypothetical protein 7658285 8330730 Amir_6518 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104164.1 7657458 D 446462 CDS YP_003104165.1 256380505 8330731 7658447..7659370 1 NC_013093.1 KEGG: GH10507 gene product from transcript GH10507- RA; hypothetical protein 7659370 8330731 Amir_6519 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104165.1 7658447 D 446462 CDS YP_003104166.1 256380506 8330732 7659642..7661042 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_4017 serine/threonine protein kinase; serine/threonine protein kinase 7661042 8330732 Amir_6520 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003104166.1 7659642 D 446462 CDS YP_003104167.1 256380507 8330733 7661187..7662848 1 NC_013093.1 PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_4017 serine/threonine protein kinase; serine/threonine protein kinase 7662848 8330733 Amir_6521 Actinosynnema mirum DSM 43827 serine/threonine protein kinase YP_003104167.1 7661187 D 446462 CDS YP_003104168.1 256380508 8330734 complement(7662882..7663784) 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aav:Aave_0303 transcriptional regulator, LysR family; LysR family transcriptional regulator 7663784 8330734 Amir_6522 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003104168.1 7662882 R 446462 CDS YP_003104169.1 256380509 8330735 7663866..7664807 1 NC_013093.1 PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: hypothetical protein; hypothetical protein 7664807 8330735 Amir_6523 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104169.1 7663866 D 446462 CDS YP_003104170.1 256380510 8330736 7664979..7665389 1 NC_013093.1 PFAM: sporulation and cell division protein SsgA; sporulation and cell division protein SsgA 7665389 8330736 Amir_6524 Actinosynnema mirum DSM 43827 sporulation and cell division protein SsgA YP_003104170.1 7664979 D 446462 CDS YP_003104171.1 256380511 8330737 complement(7665431..7666081) 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: eba:ebA6278 nitrate/nitrite response regulator; LuxR family transcriptional regulator 7666081 8330737 Amir_6525 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003104171.1 7665431 R 446462 CDS YP_003104172.1 256380512 8330738 complement(7666078..7667412) 1 NC_013093.1 PFAM: PspC domain protein; ATP-binding region ATPase domain protein; KEGG: sus:Acid_2189 histidine kinase; signal transduction histidine kinase 7667412 8330738 Amir_6526 Actinosynnema mirum DSM 43827 signal transduction histidine kinase YP_003104172.1 7666078 R 446462 CDS YP_003104173.1 256380513 8330739 7667432..7668685 1 NC_013093.1 PFAM: PspC domain protein; KEGG: aba:Acid345_1324 phage shock protein C, PspC; phage shock protein PspC 7668685 8330739 Amir_6527 Actinosynnema mirum DSM 43827 phage shock protein PspC YP_003104173.1 7667432 D 446462 CDS YP_003104174.1 256380514 8330740 7668678..7668881 1 NC_013093.1 hypothetical protein 7668881 8330740 Amir_6528 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104174.1 7668678 D 446462 CDS YP_003104175.1 256380515 8330741 complement(7669002..7670561) 1 NC_013093.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 7670561 guaA 8330741 guaA Actinosynnema mirum DSM 43827 GMP synthase YP_003104175.1 7669002 R 446462 CDS YP_003104176.1 256380516 8330742 7670661..7671377 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce4958 hypothetical protein; aminoglycoside phosphotransferase 7671377 8330742 Amir_6530 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003104176.1 7670661 D 446462 CDS YP_003104177.1 256380517 8330743 7671412..7672857 1 NC_013093.1 PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_2844 succinate-semialdehyde dehydrogenase; aldehyde dehydrogenase 7672857 8330743 Amir_6531 Actinosynnema mirum DSM 43827 aldehyde dehydrogenase YP_003104177.1 7671412 D 446462 CDS YP_003104178.1 256380518 8330744 complement(7673298..7674986) 1 NC_013093.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: scl:sce0787 hypothetical protein; glucose-methanol-choline oxidoreductase 7674986 8330744 Amir_6532 Actinosynnema mirum DSM 43827 glucose-methanol-choline oxidoreductase YP_003104178.1 7673298 R 446462 CDS YP_003104179.1 256380519 8330745 complement(7675150..7675356) 1 NC_013093.1 hypothetical protein 7675356 8330745 Amir_6533 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104179.1 7675150 R 446462 CDS YP_003104180.1 256380520 8330746 complement(7675514..7676647) 1 NC_013093.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 7676647 8330746 Amir_6534 Actinosynnema mirum DSM 43827 inosine 5-monophosphate dehydrogenase YP_003104180.1 7675514 R 446462 CDS YP_003104181.1 256380521 8330747 complement(7676679..7678190) 1 NC_013093.1 KEGG: sfu:Sfum_2122 inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; SMART: CBS domain containing protein; inosine-5'-monophosphate dehydrogenase 7678190 8330747 Amir_6535 Actinosynnema mirum DSM 43827 inosine-5'-monophosphate dehydrogenase YP_003104181.1 7676679 R 446462 CDS YP_003104182.1 256380522 8330748 7678314..7678709 1 NC_013093.1 hypothetical protein 7678709 8330748 Amir_6536 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104182.1 7678314 D 446462 CDS YP_003104183.1 256380523 8330749 complement(7678850..7679770) 1 NC_013093.1 KEGG: similar to mucin 7, salivary; hypothetical protein 7679770 8330749 Amir_6537 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104183.1 7678850 R 446462 CDS YP_003104184.1 256380524 8330750 complement(7679771..7680343) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: mno:Mnod_5360 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 7680343 8330750 Amir_6538 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003104184.1 7679771 R 446462 CDS YP_003104185.1 256380525 8330751 complement(7681488..7682084) 1 NC_013093.1 PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; KEGG: smt:Smal_2340 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator 7682084 8330751 Amir_6539 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003104185.1 7681488 R 446462 CDS YP_003104186.1 256380526 8330752 complement(7682165..7683715) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7683715 8330752 Amir_6540 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104186.1 7682165 R 446462 CDS YP_003104187.1 256380527 8330753 complement(7683992..7684921) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: mxa:MXAN_0904 B12 binding domain/transcriptional regulator, MerR family; MerR family transcriptional regulator 7684921 8330753 Amir_6541 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003104187.1 7683992 R 446462 CDS YP_003104188.1 256380528 8330754 7685149..7685484 1 NC_013093.1 PFAM: transcription factor WhiB; transcription factor WhiB 7685484 8330754 Amir_6542 Actinosynnema mirum DSM 43827 transcription factor WhiB YP_003104188.1 7685149 D 446462 CDS YP_003104189.1 256380529 8330755 complement(7685657..7687282) 1 NC_013093.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: sus:Acid_6747 chaperonin GroEL; chaperonin GroEL 7687282 8330755 Amir_6543 Actinosynnema mirum DSM 43827 chaperonin GroEL YP_003104189.1 7685657 R 446462 CDS YP_003104190.1 256380530 8330756 complement(7687367..7687660) 1 NC_013093.1 PFAM: chaperonin Cpn10; KEGG: bcu:BCAH820_0292 chaperonin, 10 kDa; chaperonin Cpn10 7687660 8330756 Amir_6544 Actinosynnema mirum DSM 43827 chaperonin Cpn10 YP_003104190.1 7687367 R 446462 CDS YP_003104191.1 256380531 8330757 complement(7688022..7688855) 1 NC_013093.1 hypothetical protein 7688855 8330757 Amir_6545 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104191.1 7688022 R 446462 CDS YP_003104192.1 256380532 8330758 complement(7689012..7690064) 1 NC_013093.1 KEGG: afw:Anae109_3813 metalloendopeptidase glycoprotease family; TIGRFAM: metalloendopeptidase, glycoprotease family; PFAM: peptidase M22 glycoprotease; metalloendopeptidase, glycoprotease family 7690064 8330758 Amir_6546 Actinosynnema mirum DSM 43827 metalloendopeptidase, glycoprotease family YP_003104192.1 7689012 R 446462 CDS YP_003104193.1 256380533 8330759 complement(7690057..7690515) 1 NC_013093.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: smt:Smal_0531 ribosomal-protein-alanine acetyltransferase; ribosomal-protein-alanine acetyltransferase 7690515 8330759 Amir_6547 Actinosynnema mirum DSM 43827 ribosomal-protein-alanine acetyltransferase YP_003104193.1 7690057 R 446462 CDS YP_003104194.1 256380534 8330760 complement(7690512..7691210) 1 NC_013093.1 PFAM: peptidase M22 glycoprotease; KEGG: pzu:PHZ_c3457 metal-dependent protease (with possible chaperone activity); peptidase M22 glycoprotease 7691210 8330760 Amir_6548 Actinosynnema mirum DSM 43827 peptidase M22 glycoprotease YP_003104194.1 7690512 R 446462 CDS YP_003104195.1 256380535 8330761 7691276..7691662 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: rpa:RPA4825 MerR family transcriptional regulator; MerR family transcriptional regulator 7691662 8330761 Amir_6549 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003104195.1 7691276 D 446462 CDS YP_003104196.1 256380536 8330762 7691650..7691955 1 NC_013093.1 PFAM: Thioredoxin domain; KEGG: bcy:Bcer98_3221 thioredoxin; thioredoxin domain-containing protein 7691955 8330762 Amir_6550 Actinosynnema mirum DSM 43827 thioredoxin domain-containing protein YP_003104196.1 7691650 D 446462 CDS YP_003104197.1 256380537 8330763 7691986..7693338 1 NC_013093.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 7693338 8330763 Amir_6551 Actinosynnema mirum DSM 43827 acyl-CoA synthetase YP_003104197.1 7691986 D 446462 CDS YP_003104198.1 256380538 8330765 complement(7694043..7694567) 1 NC_013093.1 hypothetical protein 7694567 8330765 Amir_6553 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104198.1 7694043 R 446462 CDS YP_003104199.1 256380539 8330766 complement(7694629..7695108) 1 NC_013093.1 PFAM: protein of unknown function UPF0079; KEGG: jan:Jann_4062 hypothetical protein; hypothetical protein 7695108 8330766 Amir_6554 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104199.1 7694629 R 446462 CDS YP_003104200.1 256380540 8330767 complement(7695108..7696208) 1 NC_013093.1 PFAM: alpha/beta hydrolase fold; KEGG: scl:sce8687 hypothetical protein; alpha/beta hydrolase fold protein 7696208 8330767 Amir_6555 Actinosynnema mirum DSM 43827 alpha/beta hydrolase fold protein YP_003104200.1 7695108 R 446462 CDS YP_003104201.1 256380541 8330768 complement(7696205..7697371) 1 NC_013093.1 KEGG: dol:Dole_0057 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein; alanine racemase 7697371 8330768 Amir_6556 Actinosynnema mirum DSM 43827 alanine racemase YP_003104201.1 7696205 R 446462 CDS YP_003104202.1 256380542 8330769 complement(7697368..7698765) 1 NC_013093.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF- family domain protein; KEGG: swi:Swit_4659 carbohydrate kinase, YjeF related protein; carbohydrate kinase 7698765 8330769 Amir_6557 Actinosynnema mirum DSM 43827 carbohydrate kinase YP_003104202.1 7697368 R 446462 CDS YP_003104203.1 256380543 8330770 complement(7698890..7700752) 1 NC_013093.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 7700752 8330770 Amir_6558 Actinosynnema mirum DSM 43827 glucosamine--fructose-6-phosphate aminotransferase YP_003104203.1 7698890 R 446462 CDS YP_003104204.1 256380544 8330771 7700887..7701699 1 NC_013093.1 KEGG: scl:sce1807 hypothetical protein; dienelactone hydrolase-like protein 7701699 8330771 Amir_6559 Actinosynnema mirum DSM 43827 dienelactone hydrolase-like protein YP_003104204.1 7700887 D 446462 CDS YP_003104205.1 256380545 8330772 complement(7701823..7702305) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7702305 8330772 Amir_6560 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104205.1 7701823 R 446462 CDS YP_003104206.1 256380546 8330773 complement(7702302..7705190) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7705190 8330773 Amir_6561 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104206.1 7702302 R 446462 CDS YP_003104207.1 256380547 8330774 complement(7705187..7705480) 1 NC_013093.1 hypothetical protein 7705480 8330774 Amir_6562 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104207.1 7705187 R 446462 CDS YP_003104208.1 256380548 8330775 complement(7705799..7707133) 1 NC_013093.1 TIGRFAM: phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: pca:Pcar_1001 phosphohexomutase; phosphoglucosamine mutase 7707133 8330775 Amir_6563 Actinosynnema mirum DSM 43827 phosphoglucosamine mutase YP_003104208.1 7705799 R 446462 CDS YP_003104209.1 256380549 8330776 complement(7707252..7707902) 1 NC_013093.1 PFAM: ribosomal protein S9; KEGG: bha:BH0169 30S ribosomal protein S9; 30S ribosomal protein S9 7707902 8330776 Amir_6564 Actinosynnema mirum DSM 43827 30S ribosomal protein S9 YP_003104209.1 7707252 R 446462 CDS YP_003104210.1 256380550 8330777 complement(7707899..7708342) 1 NC_013093.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 7708342 rplM 8330777 rplM Actinosynnema mirum DSM 43827 50S ribosomal protein L13 YP_003104210.1 7707899 R 446462 CDS YP_003104211.1 256380551 8330778 complement(7708647..7708937) 1 NC_013093.1 PFAM: protein of unknown function DUF909; KEGG: hypothetical protein; hypothetical protein 7708937 8330778 Amir_6566 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104211.1 7708647 R 446462 CDS YP_003104212.1 256380552 8330779 complement(7709021..7709338) 1 NC_013093.1 PFAM: protein of unknown function DUF909; hypothetical protein 7709338 8330779 Amir_6567 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104212.1 7709021 R 446462 CDS YP_003104213.1 256380553 8330780 complement(7709487..7709903) 1 NC_013093.1 KEGG: bpl:BURPS1106A_A2538 chemotaxis histidine kinase/response regulator; chemotaxis histidine kinase/response regulator 7709903 8330780 Amir_6568 Actinosynnema mirum DSM 43827 chemotaxis histidine kinase/response regulator YP_003104213.1 7709487 R 446462 CDS YP_003104214.1 256380554 8330781 complement(7709920..7711851) 1 NC_013093.1 PFAM: Heat shock protein 70; KEGG: mag:amb3024 chaperone protein HscA; Heat shock protein 70 7711851 8330781 Amir_6569 Actinosynnema mirum DSM 43827 Heat shock protein 70 YP_003104214.1 7709920 R 446462 CDS YP_003104215.1 256380555 8330782 7712435..7713076 1 NC_013093.1 hypothetical protein 7713076 8330782 Amir_6570 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104215.1 7712435 D 446462 CDS YP_003104216.1 256380556 8330783 complement(7713178..7717179) 1 NC_013093.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: bcz:BCZK1985 FtsK/SpoIIIE family protein; cell division protein FtsK/SpoIIIE 7717179 8330783 Amir_6571 Actinosynnema mirum DSM 43827 cell division protein FtsK/SpoIIIE YP_003104216.1 7713178 R 446462 CDS YP_003104217.1 256380557 8330784 7717462..7718856 1 NC_013093.1 TIGRFAM: secretion protein snm4; PFAM: protein of unknown function DUF571; KEGG: hypothetical protein; secretion protein snm4 7718856 8330784 Amir_6572 Actinosynnema mirum DSM 43827 secretion protein snm4 YP_003104217.1 7717462 D 446462 CDS YP_003104218.1 256380558 8330785 7718868..7720346 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: bca:BCE_2410 alkaline serine protease; peptidase S8/S53 subtilisin kexin sedolisin 7720346 8330785 Amir_6573 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003104218.1 7718868 D 446462 CDS YP_003104219.1 256380559 8330786 complement(7720549..7721688) 1 NC_013093.1 KEGG: predicted gene, 100041170; hypothetical protein 7721688 8330786 Amir_6574 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104219.1 7720549 R 446462 CDS YP_003104220.1 256380560 8330787 complement(7721703..7722047) 1 NC_013093.1 hypothetical protein 7722047 8330787 Amir_6575 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104220.1 7721703 R 446462 CDS YP_003104221.1 256380561 8330788 complement(7722436..7724058) 1 NC_013093.1 PFAM: protein of unknown function DUF690; hypothetical protein 7724058 8330788 Amir_6576 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104221.1 7722436 R 446462 CDS YP_003104222.1 256380562 8330789 7724292..7725620 1 NC_013093.1 KEGG: GK21128 gene product from transcript GK21128- RA; hypothetical protein 7725620 8330789 Amir_6577 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104222.1 7724292 D 446462 CDS YP_003104223.1 256380563 8330790 7725617..7726342 1 NC_013093.1 hypothetical protein 7726342 8330790 Amir_6578 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104223.1 7725617 D 446462 CDS YP_003104224.1 256380564 8330792 7726642..7728201 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proprotein convertase P; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 7728201 8330792 Amir_6580 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003104224.1 7726642 D 446462 CDS YP_003104225.1 256380565 8330793 complement(7728291..7729235) 1 NC_013093.1 PFAM: tRNA pseudouridine synthase; KEGG: rpe:RPE_0654 tRNA pseudouridine synthase A; tRNA-pseudouridine synthase I 7729235 8330793 Amir_6581 Actinosynnema mirum DSM 43827 tRNA-pseudouridine synthase I YP_003104225.1 7728291 R 446462 CDS YP_003104226.1 256380566 8330794 complement(7729232..7729822) 1 NC_013093.1 TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; KEGG: dol:Dole_0734 ribosomal protein L17; 50S ribosomal protein L17 7729822 8330794 Amir_6582 Actinosynnema mirum DSM 43827 50S ribosomal protein L17 YP_003104226.1 7729232 R 446462 CDS YP_003104227.1 256380567 8330795 complement(7729881..7730933) 1 NC_013093.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 7730933 8330795 Amir_6583 Actinosynnema mirum DSM 43827 DNA-directed RNA polymerase subunit alpha YP_003104227.1 7729881 R 446462 CDS YP_003104228.1 256380568 8330796 complement(7731079..7731684) 1 NC_013093.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 7731684 rpsD 8330796 rpsD Actinosynnema mirum DSM 43827 30S ribosomal protein S4 YP_003104228.1 7731079 R 446462 CDS YP_003104229.1 256380569 8330797 complement(7731708..7732115) 1 NC_013093.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 7732115 8330797 Amir_6585 Actinosynnema mirum DSM 43827 30S ribosomal protein S11 YP_003104229.1 7731708 R 446462 CDS YP_003104230.1 256380570 8330798 complement(7732148..7732528) 1 NC_013093.1 PFAM: ribosomal protein S13; KEGG: gsu:GSU2834 30S ribosomal protein S13; 30S ribosomal protein S13 7732528 8330798 Amir_6586 Actinosynnema mirum DSM 43827 30S ribosomal protein S13 YP_003104230.1 7732148 R 446462 CDS YP_003104231.1 256380571 8330799 complement(7732746..7732859) 1 NC_013093.1 TIGRFAM: ribosomal protein L36; PFAM: ribosomal protein L36; KEGG: aba:Acid345_1250 LSU ribosomal protein L36P; 50S ribosomal protein L36 7732859 8330799 Amir_6587 Actinosynnema mirum DSM 43827 50S ribosomal protein L36 YP_003104231.1 7732746 R 446462 CDS YP_003104232.1 256380572 8330800 complement(7732910..7733131) 1 NC_013093.1 TIGRFAM: translation initiation factor IF-1; PFAM: S1 IF1 family protein; KEGG: bha:BH0158 translation initiation factor IF-1; translation initiation factor IF-1 7733131 8330800 Amir_6588 Actinosynnema mirum DSM 43827 translation initiation factor IF-1 YP_003104232.1 7732910 R 446462 CDS YP_003104233.1 256380573 8330801 complement(7733284..7733841) 1 NC_013093.1 KEGG: mpo:Mpop_2819 translation initiation factor IF-2; hypothetical protein 7733841 8330801 Amir_6589 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104233.1 7733284 R 446462 CDS YP_003104234.1 256380574 8330802 complement(7733872..7734348) 1 NC_013093.1 PFAM: protein of unknown function DUF1707; hypothetical protein 7734348 8330802 Amir_6590 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104234.1 7733872 R 446462 CDS YP_003104235.1 256380575 8330803 7734533..7734664 1 NC_013093.1 hypothetical protein 7734664 8330803 Amir_6591 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104235.1 7734533 D 446462 CDS YP_003104236.1 256380576 8330804 complement(7734801..7735577) 1 NC_013093.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: bha:BH0156 methionine aminopeptidase; methionine aminopeptidase, type I 7735577 8330804 Amir_6592 Actinosynnema mirum DSM 43827 methionine aminopeptidase, type I YP_003104236.1 7734801 R 446462 CDS YP_003104237.1 256380577 8330805 complement(7735631..7736182) 1 NC_013093.1 TIGRFAM: adenylate kinase; PFAM: adenylate kinase; KEGG: sml:Smlt3886 adenylate kinase (fragment); adenylate kinase 7736182 8330805 Amir_6593 Actinosynnema mirum DSM 43827 adenylate kinase YP_003104237.1 7735631 R 446462 CDS YP_003104238.1 256380578 8330806 complement(7736183..7737493) 1 NC_013093.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 7737493 secY 8330806 secY Actinosynnema mirum DSM 43827 preprotein translocase subunit SecY YP_003104238.1 7736183 R 446462 CDS YP_003104239.1 256380579 8330807 complement(7738012..7738455) 1 NC_013093.1 TIGRFAM: ribosomal protein L15; PFAM: ribosomal protein L15; KEGG: sfu:Sfum_1574 ribosomal protein L15; 50S ribosomal protein L15 7738455 8330807 Amir_6595 Actinosynnema mirum DSM 43827 50S ribosomal protein L15 YP_003104239.1 7738012 R 446462 CDS YP_003104240.1 256380580 8330808 complement(7738452..7738637) 1 NC_013093.1 TIGRFAM: ribosomal protein L30; PFAM: ribosomal protein L30; KEGG: bbr:BB0049 50S ribosomal protein L30; 50S ribosomal protein L30 7738637 8330808 Amir_6596 Actinosynnema mirum DSM 43827 50S ribosomal protein L30 YP_003104240.1 7738452 R 446462 CDS YP_003104241.1 256380581 8330809 complement(7738640..7739245) 1 NC_013093.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 7739245 rpsE 8330809 rpsE Actinosynnema mirum DSM 43827 30S ribosomal protein S5 YP_003104241.1 7738640 R 446462 CDS YP_003104242.1 256380582 8330810 complement(7739280..7739678) 1 NC_013093.1 TIGRFAM: ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; KEGG: bsu:BSU01320 50S ribosomal protein L18; 50S ribosomal protein L18 7739678 8330810 Amir_6598 Actinosynnema mirum DSM 43827 50S ribosomal protein L18 YP_003104242.1 7739280 R 446462 CDS YP_003104243.1 256380583 8330811 complement(7739680..7740219) 1 NC_013093.1 PFAM: ribosomal protein L6; KEGG: cak:Caul_1629 50S ribosomal protein L6; 50S ribosomal protein L6 7740219 8330811 Amir_6599 Actinosynnema mirum DSM 43827 50S ribosomal protein L6 YP_003104243.1 7739680 R 446462 CDS YP_003104244.1 256380584 8330812 complement(7740237..7740635) 1 NC_013093.1 PFAM: ribosomal protein S8; KEGG: bha:BH0148 30S ribosomal protein S8; 30S ribosomal protein S8 7740635 8330812 Amir_6600 Actinosynnema mirum DSM 43827 30S ribosomal protein S8 YP_003104244.1 7740237 R 446462 CDS YP_003104245.1 256380585 8330813 complement(7740776..7740961) 1 NC_013093.1 PFAM: ribosomal protein S14; KEGG: cju:C8J_1598 30S ribosomal protein S14; 30S ribosomal protein S14 7740961 8330813 Amir_6601 Actinosynnema mirum DSM 43827 30S ribosomal protein S14 YP_003104245.1 7740776 R 446462 CDS YP_003104246.1 256380586 8330814 complement(7740965..7741528) 1 NC_013093.1 PFAM: ribosomal protein L5; KEGG: csa:Csal_0433 50S ribosomal protein L5; 50S ribosomal protein L5 7741528 8330814 Amir_6602 Actinosynnema mirum DSM 43827 50S ribosomal protein L5 YP_003104246.1 7740965 R 446462 CDS YP_003104247.1 256380587 8330815 complement(7741528..7741842) 1 NC_013093.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 7741842 rplX 8330815 rplX Actinosynnema mirum DSM 43827 50S ribosomal protein L24 YP_003104247.1 7741528 R 446462 CDS YP_003104248.1 256380588 8330816 complement(7741845..7742213) 1 NC_013093.1 TIGRFAM: ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; KEGG: bcy:Bcer98_0114 50S ribosomal protein L14; 50S ribosomal protein L14 7742213 8330816 Amir_6604 Actinosynnema mirum DSM 43827 50S ribosomal protein L14 YP_003104248.1 7741845 R 446462 CDS YP_003104249.1 256380589 8330817 complement(7742276..7742557) 1 NC_013093.1 PFAM: ribosomal protein S17; KEGG: bsu:BSU01250 30S ribosomal protein S17; 30S ribosomal protein S17 7742557 8330817 Amir_6605 Actinosynnema mirum DSM 43827 30S ribosomal protein S17 YP_003104249.1 7742276 R 446462 CDS YP_003104250.1 256380590 8330818 complement(7742554..7742802) 1 NC_013093.1 TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: bha:BH0142 50S ribosomal protein L29; 50S ribosomal protein L29 7742802 8330818 Amir_6606 Actinosynnema mirum DSM 43827 50S ribosomal protein L29 YP_003104250.1 7742554 R 446462 CDS YP_003104251.1 256380591 8330819 complement(7742802..7743221) 1 NC_013093.1 TIGRFAM: ribosomal protein L16; PFAM: ribosomal protein L16; KEGG: bha:BH0141 50S ribosomal protein L16; 50S ribosomal protein L16 7743221 8330819 Amir_6607 Actinosynnema mirum DSM 43827 50S ribosomal protein L16 YP_003104251.1 7742802 R 446462 CDS YP_003104252.1 256380592 8330820 complement(7743225..7744052) 1 NC_013093.1 KEGG: atc:AGR_C_3546 30S ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; KH type 2 domain protein; ribosomal protein S3 domain; SMART: KH domain protein; 30S ribosomal protein S3 7744052 8330820 Amir_6608 Actinosynnema mirum DSM 43827 30S ribosomal protein S3 YP_003104252.1 7743225 R 446462 CDS YP_003104253.1 256380593 8330821 complement(7744052..7744453) 1 NC_013093.1 TIGRFAM: ribosomal protein L22; PFAM: ribosomal protein L22/L17; KEGG: bcu:BCAH820_0127 ribosomal protein L22; 50S ribosomal protein L22 7744453 8330821 Amir_6609 Actinosynnema mirum DSM 43827 50S ribosomal protein L22 YP_003104253.1 7744052 R 446462 CDS YP_003104254.1 256380594 8330822 complement(7744489..7744770) 1 NC_013093.1 TIGRFAM: ribosomal protein S19; PFAM: ribosomal protein S19/S15; KEGG: bha:BH0138 30S ribosomal protein S19; 30S ribosomal protein S19 7744770 8330822 Amir_6610 Actinosynnema mirum DSM 43827 30S ribosomal protein S19 YP_003104254.1 7744489 R 446462 CDS YP_003104255.1 256380595 8330823 complement(7744789..7745622) 1 NC_013093.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 7745622 rplB 8330823 rplB Actinosynnema mirum DSM 43827 50S ribosomal protein L2 YP_003104255.1 7744789 R 446462 CDS YP_003104256.1 256380596 8330824 complement(7745645..7745944) 1 NC_013093.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 7745944 rplW 8330824 rplW Actinosynnema mirum DSM 43827 50S ribosomal protein L23 YP_003104256.1 7745645 R 446462 CDS YP_003104257.1 256380597 8330825 complement(7745941..7746636) 1 NC_013093.1 PFAM: ribosomal protein L4/L1e; KEGG: bha:BH0135 50S ribosomal protein L4; 50S ribosomal protein L4/L1e 7746636 8330825 Amir_6613 Actinosynnema mirum DSM 43827 50S ribosomal protein L4/L1e YP_003104257.1 7745941 R 446462 CDS YP_003104258.1 256380598 8330826 complement(7746639..7747289) 1 NC_013093.1 PFAM: ribosomal protein L3; KEGG: sde:Sde_0960 50S ribosomal protein L3P; 50S ribosomal protein L3 7747289 8330826 Amir_6614 Actinosynnema mirum DSM 43827 50S ribosomal protein L3 YP_003104258.1 7746639 R 446462 CDS YP_003104259.1 256380599 8330827 complement(7747341..7747646) 1 NC_013093.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 7747646 rpsJ 8330827 rpsJ Actinosynnema mirum DSM 43827 30S ribosomal protein S10 YP_003104259.1 7747341 R 446462 CDS YP_003104260.1 256380600 8330828 complement(7747990..7749183) 1 NC_013093.1 KEGG: ppd:Ppro_0678 elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain protein; elongation factor Tu domain 2 protein; translation elongation factor Tu 7749183 8330828 Amir_6616 Actinosynnema mirum DSM 43827 translation elongation factor Tu YP_003104260.1 7747990 R 446462 CDS YP_003104261.1 256380601 8330829 complement(7749321..7751423) 1 NC_013093.1 TIGRFAM: translation elongation factor G; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: hac:Hac_1575 elongation factor G; translation elongation factor G 7751423 8330829 Amir_6617 Actinosynnema mirum DSM 43827 translation elongation factor G YP_003104261.1 7749321 R 446462 CDS YP_003104262.1 256380602 8330830 complement(7751511..7751981) 1 NC_013093.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 7751981 8330830 Amir_6618 Actinosynnema mirum DSM 43827 30S ribosomal protein S7 YP_003104262.1 7751511 R 446462 CDS YP_003104263.1 256380603 8330831 complement(7751981..7752355) 1 NC_013093.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 7752355 rpsL 8330831 rpsL Actinosynnema mirum DSM 43827 30S ribosomal protein S12 YP_003104263.1 7751981 R 446462 CDS YP_003104264.1 256380604 8330832 7752965..7753294 1 NC_013093.1 KEGG: similar to pinin; hypothetical protein 7753294 8330832 Amir_6620 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104264.1 7752965 D 446462 CDS YP_003104265.1 256380605 8330833 7753306..7753608 1 NC_013093.1 hypothetical protein 7753608 8330833 Amir_6621 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104265.1 7753306 D 446462 CDS YP_003104266.1 256380606 8330834 complement(7754414..7754569) 1 NC_013093.1 hypothetical protein 7754569 8330834 Amir_6622 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104266.1 7754414 R 446462 CDS YP_003104267.1 256380607 8330836 7755319..7756191 1 NC_013093.1 PFAM: aminoglycoside phosphotransferase; KEGG: mch:Mchl_5542 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 7756191 8330836 Amir_6624 Actinosynnema mirum DSM 43827 aminoglycoside phosphotransferase YP_003104267.1 7755319 D 446462 CDS YP_003104268.1 256380608 8330837 7756228..7756521 1 NC_013093.1 KEGG: tbd:Tbd_1197 hypothetical protein; hypothetical protein 7756521 8330837 Amir_6625 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104268.1 7756228 D 446462 CDS YP_003104269.1 256380609 8330838 complement(7756765..7760661) 1 NC_013093.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 7760661 8330838 Amir_6626 Actinosynnema mirum DSM 43827 DNA-directed RNA polymerase subunit beta' YP_003104269.1 7756765 R 446462 CDS YP_003104270.1 256380610 8330839 complement(7760779..7764261) 1 NC_013093.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 7764261 rpoB 8330839 rpoB Actinosynnema mirum DSM 43827 DNA-directed RNA polymerase subunit beta YP_003104270.1 7760779 R 446462 CDS YP_003104271.1 256380611 8330840 complement(7764674..7765789) 1 NC_013093.1 KEGG: fibrocystin-L-like protein; hypothetical protein 7765789 8330840 Amir_6628 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104271.1 7764674 R 446462 CDS YP_003104272.1 256380612 8330841 complement(7765804..7766697) 1 NC_013093.1 KEGG: PF9; flagellar inner arm dynein 1 heavy chain alpha; hypothetical protein 7766697 8330841 Amir_6629 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104272.1 7765804 R 446462 CDS YP_003104273.1 256380613 8330842 complement(7766708..7768123) 1 NC_013093.1 KEGG: rce:RC1_1665 HAMP domain protein; ABC transporter periplasmic protein 7768123 8330842 Amir_6630 Actinosynnema mirum DSM 43827 ABC transporter periplasmic protein YP_003104273.1 7766708 R 446462 CDS YP_003104274.1 256380614 8330843 complement(7768123..7768476) 1 NC_013093.1 PFAM: Mammalian cell entry related domain protein; KEGG: rce:RC1_0924 ABC transporter substrate binding protein; mammalian cell entry related domain-containing protein 7768476 8330843 Amir_6631 Actinosynnema mirum DSM 43827 mammalian cell entry related domain-containing protein YP_003104274.1 7768123 R 446462 CDS YP_003104275.1 256380615 8330844 complement(7768478..7769464) 1 NC_013093.1 PFAM: Mammalian cell entry related domain protein; KEGG: gme:Gmet_1272 virulence factor MCE-like protein-related protein; Mammalian cell entry related domain-containing protein 7769464 8330844 Amir_6632 Actinosynnema mirum DSM 43827 Mammalian cell entry related domain-containing protein YP_003104275.1 7768478 R 446462 CDS YP_003104276.1 256380616 8330845 complement(7769461..7770300) 1 NC_013093.1 PFAM: protein of unknown function DUF140; KEGG: ank:AnaeK_1997 protein of unknown function DUF140; hypothetical protein 7770300 8330845 Amir_6633 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104276.1 7769461 R 446462 CDS YP_003104277.1 256380617 8330846 complement(7770302..7771084) 1 NC_013093.1 PFAM: protein of unknown function DUF140; KEGG: ade:Adeh_1863 ABC amino acid transporter, inner membrane subunit; hypothetical protein 7771084 8330846 Amir_6634 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104277.1 7770302 R 446462 CDS YP_003104278.1 256380618 8330847 complement(7771081..7772172) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sat:SYN_00410 ABC-type transport system, ATP- binding component; ABC transporter 7772172 8330847 Amir_6635 Actinosynnema mirum DSM 43827 ABC transporter YP_003104278.1 7771081 R 446462 CDS YP_003104279.1 256380619 8330848 complement(7772363..7772746) 1 NC_013093.1 TIGRFAM: ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12; KEGG: bha:BH0122 50S ribosomal protein L7/L12; 50S ribosomal protein L7/L12 7772746 8330848 Amir_6636 Actinosynnema mirum DSM 43827 50S ribosomal protein L7/L12 YP_003104279.1 7772363 R 446462 CDS YP_003104280.1 256380620 8330849 complement(7772809..7773363) 1 NC_013093.1 PFAM: ribosomal protein L10; KEGG: gox:GOX0388 50S ribosomal protein L10P; 50S ribosomal protein L10 7773363 8330849 Amir_6637 Actinosynnema mirum DSM 43827 50S ribosomal protein L10 YP_003104280.1 7772809 R 446462 CDS YP_003104281.1 256380621 8330850 7773626..7774561 1 NC_013093.1 KEGG: rpa:RPA0213 OmpA family protein; hypothetical protein 7774561 8330850 Amir_6638 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104281.1 7773626 D 446462 CDS YP_003104282.1 256380622 8330851 complement(7774640..7775356) 1 NC_013093.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 7775356 rplA 8330851 rplA Actinosynnema mirum DSM 43827 50S ribosomal protein L1 YP_003104282.1 7774640 R 446462 CDS YP_003104283.1 256380623 8330852 complement(7775451..7775885) 1 NC_013093.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 7775885 rplK 8330852 rplK Actinosynnema mirum DSM 43827 50S ribosomal protein L11 YP_003104283.1 7775451 R 446462 CDS YP_003104284.1 256380624 8330853 complement(7775994..7776794) 1 NC_013093.1 KEGG: bha:BH0118 transcription antitermination protein NusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: NGN domain protein; KOW domain protein; SMART: NGN domain protein; NusG antitermination factor 7776794 8330853 Amir_6641 Actinosynnema mirum DSM 43827 NusG antitermination factor YP_003104284.1 7775994 R 446462 CDS YP_003104285.1 256380625 8330854 complement(7776880..7777290) 1 NC_013093.1 TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; KEGG: sfu:Sfum_1543 preprotein translocase, SecE subunit; preprotein translocase subunit SecE 7777290 8330854 Amir_6642 Actinosynnema mirum DSM 43827 preprotein translocase subunit SecE YP_003104285.1 7776880 R 446462 CDS YP_003104286.1 256380626 8330856 7777575..7778816 1 NC_013093.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 7778816 8330856 Amir_6643 Actinosynnema mirum DSM 43827 aspartate aminotransferase YP_003104286.1 7777575 D 446462 CDS YP_003104287.1 256380627 8330857 7779054..7779665 1 NC_013093.1 KEGG: xom:XOO_0364 hypothetical protein; hypothetical protein 7779665 8330857 Amir_6644 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104287.1 7779054 D 446462 CDS YP_003104288.1 256380628 8330858 7779776..7780174 1 NC_013093.1 hypothetical protein 7780174 8330858 Amir_6645 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104288.1 7779776 D 446462 CDS YP_003104289.1 256380629 8330859 complement(7780241..7780660) 1 NC_013093.1 PFAM: MaoC domain protein dehydratase; KEGG: dal:Dalk_1161 MaoC domain protein dehydratase; MaoC domain-containing protein dehydratase 7780660 8330859 Amir_6646 Actinosynnema mirum DSM 43827 MaoC domain-containing protein dehydratase YP_003104289.1 7780241 R 446462 CDS YP_003104290.1 256380630 8330860 complement(7780657..7781103) 1 NC_013093.1 KEGG: rpt:Rpal_3723 hypothetical protein; hypothetical protein 7781103 8330860 Amir_6647 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104290.1 7780657 R 446462 CDS YP_003104291.1 256380631 8330861 complement(7781176..7781340) 1 NC_013093.1 TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: ribosomal protein L33; K02913 large subunit ribosomal protein L33; 50S ribosomal protein L33 7781340 8330861 Amir_6648 Actinosynnema mirum DSM 43827 50S ribosomal protein L33 YP_003104291.1 7781176 R 446462 CDS YP_003104292.1 256380632 8330864 complement(7781913..7784528) 1 NC_013093.1 KEGG: xac:XAC2711 phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; diguanylate cyclase/phosphodiesterase with GAF sensor 7784528 8330864 Amir_6649 Actinosynnema mirum DSM 43827 diguanylate cyclase/phosphodiesterase with GAF sensor YP_003104292.1 7781913 R 446462 CDS YP_003104293.1 256380633 8330865 complement(7785339..7785860) 1 NC_013093.1 KEGG: bpm:BURPS1710b_A0674 hypothetical protein; hypothetical protein 7785860 8330865 Amir_6650 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104293.1 7785339 R 446462 CDS YP_003104294.1 256380634 8330866 7786131..7786376 1 NC_013093.1 hypothetical protein 7786376 8330866 Amir_6651 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104294.1 7786131 D 446462 CDS YP_003104295.1 256380635 8330867 complement(7786481..7787404) 1 NC_013093.1 KEGG: sml:Smlt3065 hypothetical protein; hypothetical protein 7787404 8330867 Amir_6652 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104295.1 7786481 R 446462 CDS YP_003104296.1 256380636 8330869 7787680..7788171 1 NC_013093.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 7788171 8330869 Amir_6653 Actinosynnema mirum DSM 43827 nucleotide-binding protein YP_003104296.1 7787680 D 446462 CDS YP_003104297.1 256380637 8330870 7788168..7789046 1 NC_013093.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: pcr:Pcryo_0625 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase 7789046 8330870 Amir_6654 Actinosynnema mirum DSM 43827 glucose-1-phosphate thymidylyltransferase YP_003104297.1 7788168 D 446462 CDS YP_003104298.1 256380638 8330871 complement(7789078..7789938) 1 NC_013093.1 PFAM: peptidase M48 Ste24p; KEGG: bxe:Bxe_A4413 heat shock protein HtpX; peptidase M48 Ste24p 7789938 8330871 Amir_6655 Actinosynnema mirum DSM 43827 peptidase M48 Ste24p YP_003104298.1 7789078 R 446462 CDS YP_003104299.1 256380639 8330872 complement(7789973..7790494) 1 NC_013093.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ank:AnaeK_1272 4Fe-4S ferredoxin iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 7790494 8330872 Amir_6656 Actinosynnema mirum DSM 43827 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_003104299.1 7789973 R 446462 CDS YP_003104300.1 256380640 8330873 complement(7790487..7791077) 1 NC_013093.1 PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: mrd:Mrad2831_2058 NADH (or F420H2) dehydrogenase, subunit C; NADH dehydrogenase (ubiquinone) 30 kDa subunit 7791077 8330873 Amir_6657 Actinosynnema mirum DSM 43827 NADH dehydrogenase (ubiquinone) 30 kDa subunit YP_003104300.1 7790487 R 446462 CDS YP_003104301.1 256380641 8330874 complement(7791077..7791490) 1 NC_013093.1 TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: gbm:Gbem_3925 NADH-quinone oxidoreductase, B subunit; NADH-quinone oxidoreductase subunit B 7791490 8330874 Amir_6658 Actinosynnema mirum DSM 43827 NADH-quinone oxidoreductase subunit B YP_003104301.1 7791077 R 446462 CDS YP_003104302.1 256380642 8330875 7791736..7792779 1 NC_013093.1 PFAM: regulatory protein LysR; KEGG: rpb:RPB_4498 hypothetical protein; LysR family transcriptional regulator 7792779 8330875 Amir_6659 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003104302.1 7791736 D 446462 CDS YP_003104303.1 256380643 8330876 complement(7792776..7792925) 1 NC_013093.1 hypothetical protein 7792925 8330876 Amir_6660 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104303.1 7792776 R 446462 CDS YP_003104304.1 256380644 8330877 complement(7793666..7794544) 1 NC_013093.1 PFAM: amidinotransferase; KEGG: aeh:Mlg_0130 amidinotransferase; amidinotransferase 7794544 8330877 Amir_6661 Actinosynnema mirum DSM 43827 amidinotransferase YP_003104304.1 7793666 R 446462 CDS YP_003104305.1 256380645 8330878 7794611..7795060 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: bvi:Bcep1808_5003 AsnC family transcriptional regulator; AsnC family transcriptional regulator 7795060 8330878 Amir_6662 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003104305.1 7794611 D 446462 CDS YP_003104306.1 256380646 8330879 7795205..7795966 1 NC_013093.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 7795966 8330879 Amir_6663 Actinosynnema mirum DSM 43827 enoyl-CoA hydratase YP_003104306.1 7795205 D 446462 CDS YP_003104307.1 256380647 8330880 7796218..7798101 1 NC_013093.1 PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: eba:ebA3149 2-oxoglutarate ferredoxin oxidoreductase alpha subunit; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein 7798101 8330880 Amir_6664 Actinosynnema mirum DSM 43827 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein YP_003104307.1 7796218 D 446462 CDS YP_003104308.1 256380648 8330881 7798098..7799141 1 NC_013093.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: eba:ebA3150 2-oxoglutarate ferredoxin oxidoreductase subunit beta; thiamine pyrophosphate TPP-binding domain-containing protein 7799141 8330881 Amir_6665 Actinosynnema mirum DSM 43827 thiamine pyrophosphate TPP-binding domain-containing protein YP_003104308.1 7798098 D 446462 CDS YP_003104309.1 256380649 8330882 complement(7799222..7801828) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7801828 8330882 Amir_6666 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104309.1 7799222 R 446462 CDS YP_003104310.1 256380650 8330883 7802025..7802966 1 NC_013093.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: cvi:CV_0304 RarD protein, chloamphenicol sensitive; RarD protein, DMT superfamily transporter 7802966 8330883 Amir_6667 Actinosynnema mirum DSM 43827 RarD protein, DMT superfamily transporter YP_003104310.1 7802025 D 446462 CDS YP_003104311.1 256380651 8330884 complement(7803110..7804111) 1 NC_013093.1 PFAM: polyprenyl synthetase; KEGG: sit:TM1040_3742 farnesyltranstransferase; polyprenyl synthetase 7804111 8330884 Amir_6668 Actinosynnema mirum DSM 43827 polyprenyl synthetase YP_003104311.1 7803110 R 446462 CDS YP_003104312.1 256380652 8330885 complement(7804133..7805716) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 7805716 8330885 Amir_6669 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit N YP_003104312.1 7804133 R 446462 CDS YP_003104313.1 256380653 8330886 complement(7805718..7807280) 1 NC_013093.1 KEGG: mgm:Mmc1_3623 proton-translocating NADH- quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); proton-translocating NADH-quinone oxidoreductase subunit M 7807280 8330886 Amir_6670 Actinosynnema mirum DSM 43827 proton-translocating NADH-quinone oxidoreductase subunit M YP_003104313.1 7805718 R 446462 CDS YP_003104314.1 256380654 8330887 complement(7807277..7809211) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 7809211 8330887 Amir_6671 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit L YP_003104314.1 7807277 R 446462 CDS YP_003104315.1 256380655 8330888 complement(7809222..7809521) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 7809521 8330888 Amir_6672 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit K YP_003104315.1 7809222 R 446462 CDS YP_003104316.1 256380656 8330889 complement(7809518..7810351) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 7810351 8330889 Amir_6673 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit J YP_003104316.1 7809518 R 446462 CDS YP_003104317.1 256380657 8330890 complement(7810348..7810914) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 7810914 8330890 Amir_6674 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit I YP_003104317.1 7810348 R 446462 CDS YP_003104318.1 256380658 8330891 complement(7810901..7812244) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 7812244 8330891 Amir_6675 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit H YP_003104318.1 7810901 R 446462 CDS YP_003104319.1 256380659 8330892 complement(7812241..7814688) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 7814688 8330892 Amir_6676 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit G YP_003104319.1 7812241 R 446462 CDS YP_003104320.1 256380660 8330893 complement(7814685..7815980) 1 NC_013093.1 KEGG: sme:SMa1525 NuoF2 NADH I chain F; TIGRFAM: NADH-quinone oxidoreductase, F subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH-quinone oxidoreductase subunit F 7815980 8330893 Amir_6677 Actinosynnema mirum DSM 43827 NADH-quinone oxidoreductase subunit F YP_003104320.1 7814685 R 446462 CDS YP_003104321.1 256380661 8330894 complement(7815990..7816754) 1 NC_013093.1 PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: mag:amb2783 NADH:ubiquinone oxidoreductase 24 kD subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit 7816754 8330894 Amir_6678 Actinosynnema mirum DSM 43827 NADH dehydrogenase (ubiquinone) 24 kDa subunit YP_003104321.1 7815990 R 446462 CDS YP_003104322.1 256380662 8330895 complement(7816751..7818202) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 7818202 8330895 Amir_6679 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit D YP_003104322.1 7816751 R 446462 CDS YP_003104323.1 256380663 8330896 complement(7818199..7818957) 1 NC_013093.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 7818957 8330896 Amir_6680 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit C YP_003104323.1 7818199 R 446462 CDS YP_003104324.1 256380664 8330897 complement(7818963..7819511) 1 NC_013093.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 7819511 8330897 Amir_6681 Actinosynnema mirum DSM 43827 NADH dehydrogenase subunit B YP_003104324.1 7818963 R 446462 CDS YP_003104325.1 256380665 8330898 complement(7819523..7819888) 1 NC_013093.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; KEGG: glo:Glov_3138 NADH-ubiquinone/plastoquinone oxidoreductase chain 3; NADH-ubiquinone/plastoquinone oxidoreductase chain 3 7819888 8330898 Amir_6682 Actinosynnema mirum DSM 43827 NADH-ubiquinone/plastoquinone oxidoreductase chain 3 YP_003104325.1 7819523 R 446462 CDS YP_003104326.1 256380666 8330899 complement(7820237..7821517) 1 NC_013093.1 TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase; KEGG: pna:Pnap_1343 geranylgeranyl reductase; geranylgeranyl reductase 7821517 8330899 Amir_6683 Actinosynnema mirum DSM 43827 geranylgeranyl reductase YP_003104326.1 7820237 R 446462 CDS YP_003104327.1 256380667 8330900 complement(7822409..7823101) 1 NC_013093.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: sgl:SG0109 ubiquinone/menaquinone biosynthesis methyltransferase; ubiquinone/menaquinone biosynthesis methyltransferase 7823101 8330900 Amir_6684 Actinosynnema mirum DSM 43827 ubiquinone/menaquinone biosynthesis methyltransferase YP_003104327.1 7822409 R 446462 CDS YP_003104328.1 256380668 8330901 7823259..7824083 1 NC_013093.1 PFAM: inositol monophosphatase; KEGG: ade:Adeh_3387 inositol-1(or 4)- monophosphatase; inositol monophosphatase 7824083 8330901 Amir_6685 Actinosynnema mirum DSM 43827 inositol monophosphatase YP_003104328.1 7823259 D 446462 CDS YP_003104329.1 256380669 8330902 7824056..7824169 1 NC_013093.1 hypothetical protein 7824169 8330902 Amir_6686 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104329.1 7824056 D 446462 CDS YP_003104330.1 256380670 8330903 complement(7824156..7824836) 1 NC_013093.1 KEGG: predicted protein; hypothetical protein 7824836 8330903 Amir_6687 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104330.1 7824156 R 446462 CDS YP_003104331.1 256380671 8330904 complement(7824854..7825879) 1 NC_013093.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: azo:azo0308 phenylacetic acid degradation NADH oxidoreductase PaaE; phenylacetate-CoA oxygenase/reductase subunit PaaK 7825879 8330904 Amir_6688 Actinosynnema mirum DSM 43827 phenylacetate-CoA oxygenase/reductase subunit PaaK YP_003104331.1 7824854 R 446462 CDS YP_003104332.1 256380672 8330905 complement(7825880..7826392) 1 NC_013093.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: mno:Mnod_7196 phenylacetate-CoA oxygenase, PaaJ subunit; phenylacetate-CoA oxygenase subunit PaaJ 7826392 8330905 Amir_6689 Actinosynnema mirum DSM 43827 phenylacetate-CoA oxygenase subunit PaaJ YP_003104332.1 7825880 R 446462 CDS YP_003104333.1 256380673 8330906 complement(7826389..7827342) 1 NC_013093.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: rpd:RPD_1826 phenylacetate-CoA oxygenase, PaaI subunit; phenylacetate-CoA oxygenase subunit PaaI 7827342 8330906 Amir_6690 Actinosynnema mirum DSM 43827 phenylacetate-CoA oxygenase subunit PaaI YP_003104333.1 7826389 R 446462 CDS YP_003104334.1 256380674 8330907 complement(7827351..7827641) 1 NC_013093.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; KEGG: pde:Pden_4809 phenylacetate-CoA oxygenase, PaaH subunit; phenylacetate-CoA oxygenase subunit PaaH 7827641 8330907 Amir_6691 Actinosynnema mirum DSM 43827 phenylacetate-CoA oxygenase subunit PaaH YP_003104334.1 7827351 R 446462 CDS YP_003104335.1 256380675 8330908 complement(7827638..7828573) 1 NC_013093.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 7828573 paaA 8330908 paaA Actinosynnema mirum DSM 43827 phenylacetate-CoA oxygenase subunit PaaA YP_003104335.1 7827638 R 446462 CDS YP_003104336.1 256380676 8330909 complement(7828617..7829168) 1 NC_013093.1 hypothetical protein 7829168 8330909 Amir_6693 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104336.1 7828617 R 446462 CDS YP_003104337.1 256380677 8330910 7829180..7830421 1 NC_013093.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: scl:sce5042 hypothetical protein; isochorismate synthase 7830421 8330910 Amir_6694 Actinosynnema mirum DSM 43827 isochorismate synthase YP_003104337.1 7829180 D 446462 CDS YP_003104338.1 256380678 8330911 complement(7830470..7831516) 1 NC_013093.1 PFAM: ADP-ribosylation/Crystallin J1; KEGG: dol:Dole_0265 ADP-ribosylation/crystallin J1; ADP-ribosylation/Crystallin J1 7831516 8330911 Amir_6695 Actinosynnema mirum DSM 43827 ADP-ribosylation/Crystallin J1 YP_003104338.1 7830470 R 446462 CDS YP_003104339.1 256380679 8330912 7831575..7832654 1 NC_013093.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sbp:Sbal223_2267 pyridoxal-5'-phosphate- dependent protein beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit 7832654 8330912 Amir_6696 Actinosynnema mirum DSM 43827 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003104339.1 7831575 D 446462 CDS YP_003104340.1 256380680 8330913 7832802..7833200 1 NC_013093.1 hypothetical protein 7833200 8330913 Amir_6697 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104340.1 7832802 D 446462 CDS YP_003104341.1 256380681 8330914 complement(7833247..7834119) 1 NC_013093.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 7834119 8330914 Amir_6698 Actinosynnema mirum DSM 43827 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_003104341.1 7833247 R 446462 CDS YP_003104342.1 256380682 8330915 complement(7834169..7835416) 1 NC_013093.1 KEGG: GD17417 gene product from transcript GD17417- RA; hypothetical protein 7835416 8330915 Amir_6699 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104342.1 7834169 R 446462 CDS YP_003104343.1 256380683 8330916 complement(7835532..7836593) 1 NC_013093.1 KEGG: dar:Daro_2822 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 7836593 8330916 Amir_6700 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003104343.1 7835532 R 446462 CDS YP_003104344.1 256380684 8330917 complement(7836620..7837531) 1 NC_013093.1 TIGRFAM: naphthoate synthase; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: scl:sce5310 naphthoate synthase; naphthoate synthase 7837531 8330917 Amir_6701 Actinosynnema mirum DSM 43827 naphthoate synthase YP_003104344.1 7836620 R 446462 CDS YP_003104345.1 256380685 8330918 7837843..7839477 1 NC_013093.1 TIGRFAM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; KEGG: bcy:Bcer98_3493 2-succinyl-6-hydroxy-2,4- cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase 7839477 8330918 Amir_6702 Actinosynnema mirum DSM 43827 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase YP_003104345.1 7837843 D 446462 CDS YP_003104346.1 256380686 8330919 7839546..7841162 1 NC_013093.1 PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: sus:Acid_2560 peptidase M1, membrane alanine aminopeptidase; peptidase M1 membrane alanine aminopeptidase 7841162 8330919 Amir_6703 Actinosynnema mirum DSM 43827 peptidase M1 membrane alanine aminopeptidase YP_003104346.1 7839546 D 446462 CDS YP_003104347.1 256380687 8330920 complement(7841222..7841431) 1 NC_013093.1 hypothetical protein 7841431 8330920 Amir_6704 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104347.1 7841222 R 446462 CDS YP_003104348.1 256380688 8330921 7841578..7842456 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: xca:xccb100_3044 transcriptional regulator; helix-turn-helix domain-containing protein 7842456 8330921 Amir_6705 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003104348.1 7841578 D 446462 CDS YP_003104349.1 256380689 8330922 7842459..7842638 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 7842638 8330922 Amir_6706 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104349.1 7842459 D 446462 CDS YP_003104350.1 256380690 8330923 complement(7842819..7843118) 1 NC_013093.1 hypothetical protein 7843118 8330923 Amir_6707 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104350.1 7842819 R 446462 CDS YP_003104351.1 256380691 8330924 complement(7843123..7843584) 1 NC_013093.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: scl:sce5626 leucine responsive regulatory protein; AsnC family transcriptional regulator 7843584 8330924 Amir_6708 Actinosynnema mirum DSM 43827 AsnC family transcriptional regulator YP_003104351.1 7843123 R 446462 CDS YP_003104352.1 256380692 8330925 7843734..7843952 1 NC_013093.1 TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; KEGG: cps:CPS_1619 DNA-binding response regulator; excisionase family DNA binding domain-containing protein 7843952 8330925 Amir_6709 Actinosynnema mirum DSM 43827 excisionase family DNA binding domain-containing protein YP_003104352.1 7843734 D 446462 CDS YP_003104353.1 256380693 8330926 7844081..7844263 1 NC_013093.1 hypothetical protein 7844263 8330926 Amir_6710 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104353.1 7844081 D 446462 CDS YP_003104354.1 256380694 8330927 complement(7844485..7845972) 1 NC_013093.1 KEGG: GG20667 gene product from transcript GG20667- RA; chromosome partitioning ATPase 7845972 8330927 Amir_6711 Actinosynnema mirum DSM 43827 chromosome partitioning ATPase YP_003104354.1 7844485 R 446462 CDS YP_003104355.1 256380695 8330928 complement(7846106..7847071) 1 NC_013093.1 TIGRFAM: cytochrome C-type biogenesis protein CcsB; PFAM: cytochrome C assembly protein; KEGG: pca:Pcar_3065 cytochrome C biogenesis protein; cytochrome C biogenesis protein CcsB 7847071 8330928 Amir_6712 Actinosynnema mirum DSM 43827 cytochrome C biogenesis protein CcsB YP_003104355.1 7846106 R 446462 CDS YP_003104356.1 256380696 8330929 complement(7847071..7848627) 1 NC_013093.1 PFAM: ResB family protein; KEGG: cvi:CV_4387 cytochrome C-type biogenesis protein; ResB family protein 7848627 8330929 Amir_6713 Actinosynnema mirum DSM 43827 ResB family protein YP_003104356.1 7847071 R 446462 CDS YP_003104357.1 256380697 8330930 complement(7848627..7849427) 1 NC_013093.1 PFAM: cytochrome C biogenesis protein transmembrane region; KEGG: rpd:RPD_4260 cytochrome C biogenesis protein, transmembrane region; cytochrome c biogenesis protein transmembrane protein 7849427 8330930 Amir_6714 Actinosynnema mirum DSM 43827 cytochrome c biogenesis protein transmembrane protein YP_003104357.1 7848627 R 446462 CDS YP_003104358.1 256380698 8330931 7849526..7850587 1 NC_013093.1 KEGG: hch:HCH_01837 fibronectin type III domain- containing protein; hypothetical protein 7850587 8330931 Amir_6715 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104358.1 7849526 D 446462 CDS YP_003104359.1 256380699 8330932 complement(7850973..7851947) 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: mlo:mll2594 quinone oxidoreductase; alcohol dehydrogenase GroES domain-containing protein 7851947 8330932 Amir_6716 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003104359.1 7850973 R 446462 CDS YP_003104360.1 256380700 8330933 complement(7851985..7852572) 1 NC_013093.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sfr:Sfri_1234 redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 7852572 8330933 Amir_6717 Actinosynnema mirum DSM 43827 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_003104360.1 7851985 R 446462 CDS YP_003104361.1 256380701 8330934 complement(7852569..7853198) 1 NC_013093.1 PFAM: phosphoglycerate mutase; KEGG: afr:AFE_0621 phosphoglycerate mutase family protein; phosphoglycerate mutase 7853198 8330934 Amir_6718 Actinosynnema mirum DSM 43827 phosphoglycerate mutase YP_003104361.1 7852569 R 446462 CDS YP_003104362.1 256380702 8330935 complement(7853195..7854490) 1 NC_013093.1 TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; aminotransferase class I and II; KEGG: bbr:BB4409 glutamate-1-semialdehyde 2,1- aminomutase; glutamate-1-semialdehyde-2,1-aminomutase 7854490 8330935 Amir_6719 Actinosynnema mirum DSM 43827 glutamate-1-semialdehyde-2,1-aminomutase YP_003104362.1 7853195 R 446462 CDS YP_003104363.1 256380703 8330936 complement(7854596..7855090) 1 NC_013093.1 KEGG: Hypothetical protein CBG04716; hypothetical protein 7855090 8330936 Amir_6720 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104363.1 7854596 R 446462 CDS YP_003104364.1 256380704 8330937 complement(7855104..7855547) 1 NC_013093.1 hypothetical protein 7855547 8330937 Amir_6721 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104364.1 7855104 R 446462 CDS YP_003104365.1 256380705 8330938 complement(7855550..7856329) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7856329 8330938 Amir_6722 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104365.1 7855550 R 446462 CDS YP_003104366.1 256380706 8330939 complement(7856479..7856997) 1 NC_013093.1 hypothetical protein 7856997 8330939 Amir_6723 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104366.1 7856479 R 446462 CDS YP_003104367.1 256380707 8330940 complement(7857069..7857671) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7857671 8330940 Amir_6724 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104367.1 7857069 R 446462 CDS YP_003104368.1 256380708 8330941 complement(7857770..7858387) 1 NC_013093.1 KEGG: scl:sce6476 hypothetical protein; hypothetical protein 7858387 8330941 Amir_6725 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104368.1 7857770 R 446462 CDS YP_003104369.1 256380709 8330942 complement(7858442..7859068) 1 NC_013093.1 hypothetical protein 7859068 8330942 Amir_6726 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104369.1 7858442 R 446462 CDS YP_003104370.1 256380710 8330943 complement(7859068..7860042) 1 NC_013093.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 7860042 8330943 Amir_6727 Actinosynnema mirum DSM 43827 delta-aminolevulinic acid dehydratase YP_003104370.1 7859068 R 446462 CDS YP_003104371.1 256380711 8330944 complement(7860477..7862009) 1 NC_013093.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrinogen III synthase HEM4; KEGG: sfu:Sfum_3201 uroporphyrin-III C- methyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase 7862009 8330944 Amir_6728 Actinosynnema mirum DSM 43827 uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_003104371.1 7860477 R 446462 CDS YP_003104372.1 256380712 8330945 complement(7862024..7862965) 1 NC_013093.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 7862965 hemC 8330945 hemC Actinosynnema mirum DSM 43827 porphobilinogen deaminase YP_003104372.1 7862024 R 446462 CDS YP_003104373.1 256380713 8330946 complement(7862962..7864278) 1 NC_013093.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 7864278 hemA 8330946 hemA Actinosynnema mirum DSM 43827 glutamyl-tRNA reductase YP_003104373.1 7862962 R 446462 CDS YP_003104374.1 256380714 8330947 complement(7864325..7865095) 1 NC_013093.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 7865095 8330947 Amir_6731 Actinosynnema mirum DSM 43827 redox-sensing transcriptional repressor Rex YP_003104374.1 7864325 R 446462 CDS YP_003104375.1 256380715 8330948 complement(7865360..7866010) 1 NC_013093.1 PFAM: beta-Ig-H3/fasciclin; SMART: beta-Ig-H3/fasciclin; KEGG: rpe:RPE_0476 beta-Ig-H3/fasciclin; beta-Ig-H3/fasciclin 7866010 8330948 Amir_6732 Actinosynnema mirum DSM 43827 beta-Ig-H3/fasciclin YP_003104375.1 7865360 R 446462 CDS YP_003104376.1 256380716 8330949 complement(7866093..7867919) 1 NC_013093.1 PFAM: oxidoreductase molybdopterin binding; KEGG: sme:SMa2103 oxidoreductase; molybdopterin binding oxidoreductase 7867919 8330949 Amir_6733 Actinosynnema mirum DSM 43827 molybdopterin binding oxidoreductase YP_003104376.1 7866093 R 446462 CDS YP_003104377.1 256380717 8330950 complement(7867972..7868208) 1 NC_013093.1 PFAM: glutaredoxin 2; KEGG: bpy:Bphyt_2902 glutaredoxin 2; glutaredoxin 2 7868208 8330950 Amir_6734 Actinosynnema mirum DSM 43827 glutaredoxin 2 YP_003104377.1 7867972 R 446462 CDS YP_003104378.1 256380718 8330951 complement(7868225..7869736) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mno:Mnod_7251 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 7869736 8330951 Amir_6735 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003104378.1 7868225 R 446462 CDS YP_003104379.1 256380719 8330952 7869928..7870581 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: aba:Acid345_3132 sigma-24, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 7870581 8330952 Amir_6736 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003104379.1 7869928 D 446462 CDS YP_003104380.1 256380720 8330953 7870668..7871897 1 NC_013093.1 KEGG: ank:AnaeK_2468 hypothetical protein; hypothetical protein 7871897 8330953 Amir_6737 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104380.1 7870668 D 446462 CDS YP_003104381.1 256380721 8330954 7871938..7872822 1 NC_013093.1 TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase- like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pag:PLES_41761 phosphoserine phosphatase; HAD superfamily hydrolase 7872822 8330954 Amir_6738 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003104381.1 7871938 D 446462 CDS YP_003104382.1 256380722 8330955 complement(7872970..7873968) 1 NC_013093.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: dal:Dalk_1813 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 7873968 8330955 Amir_6739 Actinosynnema mirum DSM 43827 phospholipid/glycerol acyltransferase YP_003104382.1 7872970 R 446462 CDS YP_003104383.1 256380723 8330956 complement(7874159..7875196) 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; short-chain dehydrogenase/reductase SDR; KEGG: dal:Dalk_1814 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 7875196 8330956 Amir_6740 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003104383.1 7874159 R 446462 CDS YP_003104384.1 256380724 8330957 complement(7875526..7875627) 1 NC_013093.1 PFAM: Protein of unknown function DUF1713; hypothetical protein 7875627 8330957 Amir_6741 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104384.1 7875526 R 446462 CDS YP_003104385.1 256380725 8330958 complement(7875795..7876007) 1 NC_013093.1 TIGRFAM: DNA binding domain protein, excisionase family; KEGG: afw:Anae109_1068 DNA binding domain- containing protein; excisionase family DNA binding domain-containing protein 7876007 8330958 Amir_6742 Actinosynnema mirum DSM 43827 excisionase family DNA binding domain-containing protein YP_003104385.1 7875795 R 446462 CDS YP_003104386.1 256380726 8330959 complement(7876189..7877001) 1 NC_013093.1 KEGG: mgm:Mmc1_3656 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; ketopantoate reductase ApbA/PanE domain protein; pyrroline-5-carboxylate reductase 7877001 8330959 Amir_6743 Actinosynnema mirum DSM 43827 pyrroline-5-carboxylate reductase YP_003104386.1 7876189 R 446462 CDS YP_003104387.1 256380727 8330960 complement(7877468..7878274) 1 NC_013093.1 PFAM: thioesterase superfamily protein; KEGG: dal:Dalk_1857 hypothetical protein; thioesterase superfamily protein 7878274 8330960 Amir_6744 Actinosynnema mirum DSM 43827 thioesterase superfamily protein YP_003104387.1 7877468 R 446462 CDS YP_003104388.1 256380728 8330961 complement(7878310..7879170) 1 NC_013093.1 PFAM: proline dehydrogenase; KEGG: mxa:MXAN_7405 proline dehydrogenase; proline dehydrogenase 7879170 8330961 Amir_6745 Actinosynnema mirum DSM 43827 proline dehydrogenase YP_003104388.1 7878310 R 446462 CDS YP_003104389.1 256380729 8330962 complement(7879181..7879999) 1 NC_013093.1 PFAM: xylose isomerase; KEGG: gbm:Gbem_1512 xylose isomerase domain protein TIM barrel; xylose isomerase 7879999 8330962 Amir_6746 Actinosynnema mirum DSM 43827 xylose isomerase YP_003104389.1 7879181 R 446462 CDS YP_003104390.1 256380730 8330963 complement(7879996..7881438) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7881438 8330963 Amir_6747 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104390.1 7879996 R 446462 CDS YP_003104391.1 256380731 8330964 complement(7881438..7882457) 1 NC_013093.1 PFAM: Ppx/GppA phosphatase; KEGG: afw:Anae109_0702 Ppx/GppA phosphatase; Ppx/GppA phosphatase 7882457 8330964 Amir_6748 Actinosynnema mirum DSM 43827 Ppx/GppA phosphatase YP_003104391.1 7881438 R 446462 CDS YP_003104392.1 256380732 8330965 complement(7882476..7883156) 1 NC_013093.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcb:BCB4264_A5589 DNA-binding response regulator YycF; winged helix family two component transcriptional regulator 7883156 8330965 Amir_6749 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003104392.1 7882476 R 446462 CDS YP_003104393.1 256380733 8330966 complement(7883153..7884337) 1 NC_013093.1 KEGG: glo:Glov_0589 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase 7884337 8330966 Amir_6750 Actinosynnema mirum DSM 43827 histidine kinase YP_003104393.1 7883153 R 446462 CDS YP_003104394.1 256380734 8330967 complement(7884446..7885273) 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: reu:Reut_A0010 oxidoreductase; aldo/keto reductase 7885273 8330967 Amir_6751 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003104394.1 7884446 R 446462 CDS YP_003104395.1 256380735 8330968 7885352..7885987 1 NC_013093.1 KEGG: maq:Maqu_0164 response regulator receiver protein; response regulator receiver protein 7885987 8330968 Amir_6752 Actinosynnema mirum DSM 43827 response regulator receiver protein YP_003104395.1 7885352 D 446462 CDS YP_003104396.1 256380736 8330969 complement(7886139..7886885) 1 NC_013093.1 KEGG: YALI0B02728p; K01834 phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase 1 family; PFAM: phosphoglycerate mutase; phosphoglycerate mutase 1 family 7886885 8330969 Amir_6753 Actinosynnema mirum DSM 43827 phosphoglycerate mutase 1 family YP_003104396.1 7886139 R 446462 CDS YP_003104397.1 256380737 8330970 complement(7887173..7888726) 1 NC_013093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: dsh:Dshi_0253 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 7888726 8330970 Amir_6754 Actinosynnema mirum DSM 43827 AMP-dependent synthetase and ligase YP_003104397.1 7887173 R 446462 CDS YP_003104398.1 256380738 8330971 complement(7889132..7890139) 1 NC_013093.1 KEGG: scl:sce1077 hypothetical protein; hypothetical protein 7890139 8330971 Amir_6755 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104398.1 7889132 R 446462 CDS YP_003104399.1 256380739 8330972 complement(7890207..7890704) 1 NC_013093.1 hypothetical protein 7890704 8330972 Amir_6756 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104399.1 7890207 R 446462 CDS YP_003104400.1 256380740 8330973 complement(7890701..7891954) 1 NC_013093.1 TIGRFAM: UDP-N-acetylglucosamine; PFAM: glycosyl transferase group 1; KEGG: azo:azo1809 glycosyltransferase; UDP-N-acetylglucosamine 7891954 8330973 Amir_6757 Actinosynnema mirum DSM 43827 UDP-N-acetylglucosamine YP_003104400.1 7890701 R 446462 CDS YP_003104401.1 256380741 8330974 complement(7892285..7893430) 1 NC_013093.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mca:MCA1018 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 7893430 8330974 Amir_6758 Actinosynnema mirum DSM 43827 ErfK/YbiS/YcfS/YnhG family protein YP_003104401.1 7892285 R 446462 CDS YP_003104402.1 256380742 8330975 7893534..7894265 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: scl:sce8093 oxidoreductase; short-chain dehydrogenase/reductase SDR 7894265 8330975 Amir_6759 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003104402.1 7893534 D 446462 CDS YP_003104403.1 256380743 8330976 complement(7894219..7895214) 1 NC_013093.1 KEGG: noc:Noc_1844 hypothetical protein; hypothetical protein 7895214 8330976 Amir_6760 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104403.1 7894219 R 446462 CDS YP_003104404.1 256380744 8330977 complement(7895399..7896451) 1 NC_013093.1 PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; FAD linked oxidase domain protein; KEGG: scl:sce7823 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylmuramate dehydrogenase 7896451 8330977 Amir_6761 Actinosynnema mirum DSM 43827 UDP-N-acetylmuramate dehydrogenase YP_003104404.1 7895399 R 446462 CDS YP_003104405.1 256380745 8330978 7896519..7897016 1 NC_013093.1 KEGG: hch:HCH_06841 hypothetical protein; hypothetical protein 7897016 8330978 Amir_6762 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104405.1 7896519 D 446462 CDS YP_003104406.1 256380746 8330979 7897037..7897792 1 NC_013093.1 KEGG: mxa:MXAN_2356 hypothetical protein; hypothetical protein 7897792 8330979 Amir_6763 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104406.1 7897037 D 446462 CDS YP_003104407.1 256380747 8330980 7898674..7899411 1 NC_013093.1 PFAM: protein of unknown function DUF1503; hypothetical protein 7899411 8330980 Amir_6764 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104407.1 7898674 D 446462 CDS YP_003104408.1 256380748 8330981 7899435..7900310 1 NC_013093.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 7900310 purU 8330981 purU Actinosynnema mirum DSM 43827 formyltetrahydrofolate deformylase YP_003104408.1 7899435 D 446462 CDS YP_003104409.1 256380749 8330982 7900352..7901434 1 NC_013093.1 KEGG: mxa:MXAN_2885 hypothetical protein; hypothetical protein 7901434 8330982 Amir_6766 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104409.1 7900352 D 446462 CDS YP_003104410.1 256380750 8330983 7901525..7902058 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bsu:BSU17080 transcriptional regulator; TetR family transcriptional regulator 7902058 8330983 Amir_6767 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104410.1 7901525 D 446462 CDS YP_003104411.1 256380751 8330984 complement(7902126..7902680) 1 NC_013093.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: bbr:BB1555 hypothetical protein; YbaK/prolyl-tRNA synthetase associated protein 7902680 8330984 Amir_6768 Actinosynnema mirum DSM 43827 YbaK/prolyl-tRNA synthetase associated protein YP_003104411.1 7902126 R 446462 CDS YP_003104412.1 256380752 8330985 7902855..7903619 1 NC_013093.1 PFAM: TipAS antibiotic-recognition domain protein; regulatory protein MerR; SMART: regulatory protein MerR; KEGG: ccs:CCNA_00730 transcriptional regulator SkgA; MerR family transcriptional regulator 7903619 8330985 Amir_6769 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003104412.1 7902855 D 446462 CDS YP_003104413.1 256380753 8330986 complement(7903733..7904281) 1 NC_013093.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: psa:PST_4009 protease PfpI; intracellular protease, PfpI family 7904281 8330986 Amir_6770 Actinosynnema mirum DSM 43827 intracellular protease, PfpI family YP_003104413.1 7903733 R 446462 CDS YP_003104414.1 256380754 8330987 complement(7904291..7904956) 1 NC_013093.1 KEGG: sal:Sala_0890 flavin reductase-like, FMN- binding; flavin reductase-like FMN-binding protein 7904956 8330987 Amir_6771 Actinosynnema mirum DSM 43827 flavin reductase-like FMN-binding protein YP_003104414.1 7904291 R 446462 CDS YP_003104415.1 256380755 8330988 complement(7904953..7905276) 1 NC_013093.1 hypothetical protein 7905276 8330988 Amir_6772 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104415.1 7904953 R 446462 CDS YP_003104416.1 256380756 8330989 complement(7905496..7906080) 1 NC_013093.1 KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein 7906080 8330989 Amir_6773 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104416.1 7905496 R 446462 CDS YP_003104417.1 256380757 8330990 complement(7906086..7906472) 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: azc:AZC_2073 XRE family-like protein; XRE family transcriptional regulator 7906472 8330990 Amir_6774 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003104417.1 7906086 R 446462 CDS YP_003104418.1 256380758 8330991 7906577..7907704 1 NC_013093.1 PFAM: protein-L-isoaspartate(D-aspartate) O- methyltransferase; KEGG: mex:Mext_4262 protein-L-isoaspartate O- methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase 7907704 8330991 Amir_6775 Actinosynnema mirum DSM 43827 protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_003104418.1 7906577 D 446462 CDS YP_003104419.1 256380759 8330992 complement(7908001..7909257) 1 NC_013093.1 PFAM: protein of unknown function DUF445; KEGG: swi:Swit_4743 hypothetical protein; hypothetical protein 7909257 8330992 Amir_6776 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104419.1 7908001 R 446462 CDS YP_003104420.1 256380760 8330993 7909314..7910459 1 NC_013093.1 PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mxa:MXAN_3751 aminotransferase, classes I and II; class I and II aminotransferase 7910459 8330993 Amir_6777 Actinosynnema mirum DSM 43827 class I and II aminotransferase YP_003104420.1 7909314 D 446462 CDS YP_003104421.1 256380761 8330994 complement(7910463..7912475) 1 NC_013093.1 KEGG: pag:PLES_38291 hypothetical protein; hypothetical protein 7912475 8330994 Amir_6778 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104421.1 7910463 R 446462 CDS YP_003104422.1 256380762 8330995 7912615..7913043 1 NC_013093.1 KEGG: scl:sce4225 hypothetical protein; hypothetical protein 7913043 8330995 Amir_6779 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104422.1 7912615 D 446462 CDS YP_003104423.1 256380763 8330996 complement(7913148..7913615) 1 NC_013093.1 PFAM: protein of unknown function DUF1470; KEGG: sme:SMc00597 hypothetical protein; hypothetical protein 7913615 8330996 Amir_6780 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104423.1 7913148 R 446462 CDS YP_003104424.1 256380764 8330997 7913794..7914318 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: nar:Saro_2546 PadR family transcriptional regulator; PadR family transcriptional regulator 7914318 8330997 Amir_6781 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003104424.1 7913794 D 446462 CDS YP_003104425.1 256380765 8330998 7914315..7914992 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: tgr:Tgr7_1366 lipoprotein releasing system, ATP-binding protein; ABC transporter 7914992 8330998 Amir_6782 Actinosynnema mirum DSM 43827 ABC transporter YP_003104425.1 7914315 D 446462 CDS YP_003104426.1 256380766 8330999 7914989..7917349 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: mpt:Mpe_A2047 ABC transporter, permease protein; hypothetical protein 7917349 8330999 Amir_6783 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104426.1 7914989 D 446462 CDS YP_003104427.1 256380767 8331000 7917471..7917581 1 NC_013093.1 hypothetical protein 7917581 8331000 Amir_6784 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104427.1 7917471 D 446462 CDS YP_003104428.1 256380768 8331001 7917578..7919938 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: ank:AnaeK_1836 protein of unknown function DUF214; hypothetical protein 7919938 8331001 Amir_6785 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104428.1 7917578 D 446462 CDS YP_003104429.1 256380769 8331002 7919935..7922148 1 NC_013093.1 PFAM: protein of unknown function DUF214; KEGG: rru:Rru_A3653 hypothetical protein; hypothetical protein 7922148 8331002 Amir_6786 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104429.1 7919935 D 446462 CDS YP_003104430.1 256380770 8331003 7922212..7923312 1 NC_013093.1 KEGG: acp:A2cp1_2390 transcriptional regulator, Fis family; Fis family transcriptional regulator 7923312 8331003 Amir_6787 Actinosynnema mirum DSM 43827 Fis family transcriptional regulator YP_003104430.1 7922212 D 446462 CDS YP_003104431.1 256380771 8331005 7923983..7925308 1 NC_013093.1 KEGG: proteophosphoglycan 5; hypothetical protein 7925308 8331005 Amir_6789 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104431.1 7923983 D 446462 CDS YP_003104432.1 256380772 8331006 complement(7925861..7927324) 1 NC_013093.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: pzu:PHZ_c3113 transcriptional regulator, GntR family; GntR family transcriptional regulator 7927324 8331006 Amir_6790 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003104432.1 7925861 R 446462 CDS YP_003104433.1 256380773 8331007 7927386..7928015 1 NC_013093.1 PFAM: protein of unknown function DUF161; KEGG: pzu:PHZ_c3114 hypothetical protein; hypothetical protein 7928015 8331007 Amir_6791 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104433.1 7927386 D 446462 CDS YP_003104434.1 256380774 8331008 complement(7927984..7928526) 1 NC_013093.1 PFAM: Clp domain protein; KEGG: ATP-dependent clp protease ATP-binding subunit; Clp domain-containing protein 7928526 8331008 Amir_6792 Actinosynnema mirum DSM 43827 Clp domain-containing protein YP_003104434.1 7927984 R 446462 CDS YP_003104435.1 256380775 8331009 complement(7928523..7928735) 1 NC_013093.1 hypothetical protein 7928735 8331009 Amir_6793 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104435.1 7928523 R 446462 CDS YP_003104436.1 256380776 8331010 7928818..7929588 1 NC_013093.1 KEGG: pap:PSPA7_0575 hypothetical protein; hypothetical protein 7929588 8331010 Amir_6794 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104436.1 7928818 D 446462 CDS YP_003104437.1 256380777 8331014 complement(7930622..7930867) 1 NC_013093.1 hypothetical protein 7930867 8331014 Amir_6795 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104437.1 7930622 R 446462 CDS YP_003104438.1 256380778 8331015 7931033..7931359 1 NC_013093.1 KEGG: similar to corin; hypothetical protein 7931359 8331015 Amir_6796 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104438.1 7931033 D 446462 CDS YP_003104439.1 256380779 8331016 7931418..7931630 1 NC_013093.1 PFAM: Heavy metal transport/detoxification protein; KEGG: dvm:DvMF_3169 heavy metal transport/detoxification protein; Heavy metal transport/detoxification protein 7931630 8331016 Amir_6797 Actinosynnema mirum DSM 43827 Heavy metal transport/detoxification protein YP_003104439.1 7931418 D 446462 CDS YP_003104440.1 256380780 8331017 7931636..7933855 1 NC_013093.1 TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: bsu:BSU33500 hypothetical protein; heavy metal translocating P-type ATPase 7933855 8331017 Amir_6798 Actinosynnema mirum DSM 43827 heavy metal translocating P-type ATPase YP_003104440.1 7931636 D 446462 CDS YP_003104441.1 256380781 8331018 7934057..7934374 1 NC_013093.1 hypothetical protein 7934374 8331018 Amir_6799 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104441.1 7934057 D 446462 CDS YP_003104442.1 256380782 8331019 complement(7934557..7934760) 1 NC_013093.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mpt:Mpe_A2202 cold-shock DNA-binding protein family protein; cold-shock DNA-binding domain-containing protein 7934760 8331019 Amir_6800 Actinosynnema mirum DSM 43827 cold-shock DNA-binding domain-containing protein YP_003104442.1 7934557 R 446462 CDS YP_003104443.1 256380783 8331020 complement(7934976..7935803) 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bsu:BSU27440 glutamine ABC transporter (glutamine-binding protein); family 3 extracellular solute-binding protein 7935803 8331020 Amir_6801 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003104443.1 7934976 R 446462 CDS YP_003104444.1 256380784 8331021 complement(7936033..7936881) 1 NC_013093.1 KEGG: psa:PST_3300 hypothetical protein; hypothetical protein 7936881 8331021 Amir_6802 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104444.1 7936033 R 446462 CDS YP_003104445.1 256380785 8331022 7937030..7937704 1 NC_013093.1 KEGG: Os02g0467200; hypothetical protein; hypothetical protein 7937704 8331022 Amir_6803 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104445.1 7937030 D 446462 CDS YP_003104446.1 256380786 8331023 complement(7937775..7942619) 1 NC_013093.1 KEGG: scl:sce5242 hypothetical protein; hypothetical protein 7942619 8331023 Amir_6804 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104446.1 7937775 R 446462 CDS YP_003104447.1 256380787 8331024 complement(7942616..7944622) 1 NC_013093.1 KEGG: mxa:MXAN_3571 hypothetical protein; hypothetical protein 7944622 8331024 Amir_6805 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104447.1 7942616 R 446462 CDS YP_003104448.1 256380788 8331025 complement(7944637..7945218) 1 NC_013093.1 KEGG: maq:Maqu_3701 hypothetical protein; hypothetical protein 7945218 8331025 Amir_6806 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104448.1 7944637 R 446462 CDS YP_003104449.1 256380789 8331027 complement(7945796..7946881) 1 NC_013093.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bac:BamMC406_6306 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 7946881 8331027 Amir_6807 Actinosynnema mirum DSM 43827 alcohol dehydrogenase zinc-binding domain-containing protein YP_003104449.1 7945796 R 446462 CDS YP_003104450.1 256380790 8331028 complement(7946878..7947345) 1 NC_013093.1 KEGG: spe:Spro_1171 hypothetical protein; hypothetical protein 7947345 8331028 Amir_6808 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104450.1 7946878 R 446462 CDS YP_003104451.1 256380791 8331029 complement(7947405..7947941) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mes:Meso_3334 transcriptional regulator, TetR family; TetR family transcriptional regulator 7947941 8331029 Amir_6809 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104451.1 7947405 R 446462 CDS YP_003104452.1 256380792 8331030 7947996..7948826 1 NC_013093.1 hypothetical protein 7948826 8331030 Amir_6810 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104452.1 7947996 D 446462 CDS YP_003104453.1 256380793 8331031 7949037..7950218 1 NC_013093.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: hypothetical protein; TIM-barrel protein, nifR3 family 7950218 8331031 Amir_6811 Actinosynnema mirum DSM 43827 TIM-barrel protein, nifR3 family YP_003104453.1 7949037 D 446462 CDS YP_003104454.1 256380794 8331032 7950211..7950669 1 NC_013093.1 hypothetical protein 7950669 8331032 Amir_6812 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104454.1 7950211 D 446462 CDS YP_003104455.1 256380795 8331033 7950817..7951674 1 NC_013093.1 KEGG: rfr:Rfer_4028 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 7951674 8331033 Amir_6813 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003104455.1 7950817 D 446462 CDS YP_003104456.1 256380796 8331034 7951977..7955987 1 NC_013093.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: SL44-1; basic proline-rich protein; cell envelope-related transcriptional attenuator 7955987 8331034 Amir_6814 Actinosynnema mirum DSM 43827 cell envelope-related transcriptional attenuator YP_003104456.1 7951977 D 446462 CDS YP_003104457.1 256380797 8331035 7956137..7956799 1 NC_013093.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: swi:Swit_3576 phosphate uptake regulator, PhoU; phosphate uptake regulator PhoU 7956799 8331035 Amir_6815 Actinosynnema mirum DSM 43827 phosphate uptake regulator PhoU YP_003104457.1 7956137 D 446462 CDS YP_003104458.1 256380798 8331036 complement(7956860..7957660) 1 NC_013093.1 hypothetical protein 7957660 8331036 Amir_6816 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104458.1 7956860 R 446462 CDS YP_003104459.1 256380799 8331037 complement(7957657..7959354) 1 NC_013093.1 KEGG: predicted gene, 100041170; hypothetical protein 7959354 8331037 Amir_6817 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104459.1 7957657 R 446462 CDS YP_003104460.1 256380800 8331038 complement(7959603..7960379) 1 NC_013093.1 KEGG: gur:Gura_2561 phosphate ABC transporter, ATPase subunit; TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; phosphate ABC transporter ATPase subunit 7960379 8331038 Amir_6818 Actinosynnema mirum DSM 43827 phosphate ABC transporter ATPase subunit YP_003104460.1 7959603 R 446462 CDS YP_003104461.1 256380801 8331039 complement(7960390..7961304) 1 NC_013093.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tbd:Tbd_1138 phosphate transport system permease protein 2; phosphate ABC transporter, inner membrane subunit PstA 7961304 8331039 Amir_6819 Actinosynnema mirum DSM 43827 phosphate ABC transporter, inner membrane subunit PstA YP_003104461.1 7960390 R 446462 CDS YP_003104462.1 256380802 8331040 complement(7961301..7962359) 1 NC_013093.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bpy:Bphyt_2857 phosphate ABC transporter, inner membrane subunit PstC; phosphate ABC transporter, inner membrane subunit PstC 7962359 8331040 Amir_6820 Actinosynnema mirum DSM 43827 phosphate ABC transporter, inner membrane subunit PstC YP_003104462.1 7961301 R 446462 CDS YP_003104463.1 256380803 8331041 complement(7962398..7963519) 1 NC_013093.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: scl:sce2946 phosphate ABC transporter, substrate-binding protein PstS; phosphate ABC transporter periplasmic phosphate- binding protein 7963519 8331041 Amir_6821 Actinosynnema mirum DSM 43827 phosphate ABC transporter periplasmic phosphate- binding protein YP_003104463.1 7962398 R 446462 CDS YP_003104464.1 256380804 8331042 complement(7963712..7964605) 1 NC_013093.1 TIGRFAM: mycothiol biosynthesis acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: predicted protein; mycothiol biosynthesis acetyltransferase 7964605 8331042 Amir_6822 Actinosynnema mirum DSM 43827 mycothiol biosynthesis acetyltransferase YP_003104464.1 7963712 R 446462 CDS YP_003104465.1 256380805 8331043 complement(7964718..7965470) 1 NC_013093.1 PFAM: transcriptional regulator domain protein; KEGG: bha:BH3157 two-component response regulator involved in phosphate regulation; winged helix family two component transcriptional regulator 7965470 8331043 Amir_6823 Actinosynnema mirum DSM 43827 winged helix family two component transcriptional regulator YP_003104465.1 7964718 R 446462 CDS YP_003104466.1 256380806 8331044 7965529..7966380 1 NC_013093.1 KEGG: bha:BH1308 hypothetical protein; dipeptidylaminopeptidase/acylaminoacyl- peptidase-like protein 7966380 8331044 Amir_6824 Actinosynnema mirum DSM 43827 dipeptidylaminopeptidase/acylaminoacyl- peptidase-like protein YP_003104466.1 7965529 D 446462 CDS YP_003104467.1 256380807 8331045 7966377..7967183 1 NC_013093.1 KEGG: mxa:MXAN_7418 hypothetical protein; hypothetical protein 7967183 8331045 Amir_6825 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104467.1 7966377 D 446462 CDS YP_003104468.1 256380808 8331046 7967224..7967646 1 NC_013093.1 KEGG: ank:AnaeK_1735 cytochrome C biogenesis protein transmembrane region; hypothetical protein 7967646 8331046 Amir_6826 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104468.1 7967224 D 446462 CDS YP_003104469.1 256380809 8331047 7967881..7968315 1 NC_013093.1 KEGG: tdn:Suden_0151 CDP-alcohol phosphatidyltransferase; hypothetical protein 7968315 8331047 Amir_6827 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104469.1 7967881 D 446462 CDS YP_003104470.1 256380810 8331048 7968424..7969269 1 NC_013093.1 PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: cja:CJA_2345 rhodanese-like domain protein; rhodanese domain-containing protein 7969269 8331048 Amir_6828 Actinosynnema mirum DSM 43827 rhodanese domain-containing protein YP_003104470.1 7968424 D 446462 CDS YP_003104471.1 256380811 8331049 7969269..7969571 1 NC_013093.1 KEGG: mxa:MXAN_0146 hypothetical protein; hypothetical protein 7969571 8331049 Amir_6829 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104471.1 7969269 D 446462 CDS YP_003104472.1 256380812 8331050 7969777..7969875 1 NC_013093.1 hypothetical protein 7969875 8331050 Amir_6830 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104472.1 7969777 D 446462 CDS YP_003104473.1 256380813 8331051 7969875..7970510 1 NC_013093.1 PFAM: Domain of unknown function DUF1794; KEGG: hypothetical protein; hypothetical protein 7970510 8331051 Amir_6831 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104473.1 7969875 D 446462 CDS YP_003104474.1 256380814 8331052 7970839..7971441 1 NC_013093.1 PFAM: allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 1; KEGG: aav:Aave_3511 allophanate hydrolase subunit 2; allophanate hydrolase subunit 1 7971441 8331052 Amir_6832 Actinosynnema mirum DSM 43827 allophanate hydrolase subunit 1 YP_003104474.1 7970839 D 446462 CDS YP_003104475.1 256380815 8331053 7971556..7971711 1 NC_013093.1 hypothetical protein 7971711 8331053 Amir_6833 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104475.1 7971556 D 446462 CDS YP_003104476.1 256380816 8331054 7971708..7972565 1 NC_013093.1 KEGG: aav:Aave_3511 allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; urea amidolyase-like protein 7972565 8331054 Amir_6834 Actinosynnema mirum DSM 43827 urea amidolyase-like protein YP_003104476.1 7971708 D 446462 CDS YP_003104477.1 256380817 8331055 complement(7972668..7973510) 1 NC_013093.1 PFAM: aminotransferase class IV; KEGG: bbr:BB0169 class IV aminotransferase; class IV aminotransferase 7973510 8331055 Amir_6835 Actinosynnema mirum DSM 43827 class IV aminotransferase YP_003104477.1 7972668 R 446462 CDS YP_003104478.1 256380818 8331056 7973547..7973981 1 NC_013093.1 PFAM: ferric-uptake regulator; KEGG: ank:AnaeK_2300 ferric uptake regulator, Fur family; Fur family ferric uptake regulator 7973981 8331056 Amir_6836 Actinosynnema mirum DSM 43827 Fur family ferric uptake regulator YP_003104478.1 7973547 D 446462 CDS YP_003104479.1 256380819 8331057 7973978..7975072 1 NC_013093.1 TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: mxa:MXAN_6341 glycine cleavage system T protein; folate-binding protein YgfZ 7975072 8331057 Amir_6837 Actinosynnema mirum DSM 43827 folate-binding protein YgfZ YP_003104479.1 7973978 D 446462 CDS YP_003104480.1 256380820 8331058 7975127..7975927 1 NC_013093.1 PFAM: protein of unknown function DUF849; KEGG: rfr:Rfer_3885 hypothetical protein; 3-keto-5-aminohexanoate cleavage protein 7975927 8331058 Amir_6838 Actinosynnema mirum DSM 43827 3-keto-5-aminohexanoate cleavage protein YP_003104480.1 7975127 D 446462 CDS YP_003104481.1 256380821 8331059 7975988..7976563 1 NC_013093.1 hypothetical protein 7976563 8331059 Amir_6839 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104481.1 7975988 D 446462 CDS YP_003104482.1 256380822 8331060 7976730..7977884 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: aav:Aave_4589 major facilitator superfamily MFS_1; major facilitator superfamily protein 7977884 8331060 Amir_6840 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003104482.1 7976730 D 446462 CDS YP_003104483.1 256380823 8331061 complement(7978110..7978991) 1 NC_013093.1 KEGG: bch:Bcen2424_1641 amino acid adenylation domain-containing protein; hypothetical protein 7978991 8331061 Amir_6841 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104483.1 7978110 R 446462 CDS YP_003104484.1 256380824 8331062 7979154..7979336 1 NC_013093.1 hypothetical protein 7979336 8331062 Amir_6842 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104484.1 7979154 D 446462 CDS YP_003104485.1 256380825 8331063 7979621..7980433 1 NC_013093.1 KEGG: bpm:BURPS1710b_2246 hypothetical protein; hypothetical protein 7980433 8331063 Amir_6843 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104485.1 7979621 D 446462 CDS YP_003104486.1 256380826 8331064 7980466..7981173 1 NC_013093.1 PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: dal:Dalk_5197 transcriptional regulator, Crp/Fnr family; Crp/Fnr family transcriptional regulator 7981173 8331064 Amir_6844 Actinosynnema mirum DSM 43827 Crp/Fnr family transcriptional regulator YP_003104486.1 7980466 D 446462 CDS YP_003104487.1 256380827 8331065 7981470..7981847 1 NC_013093.1 hypothetical protein 7981847 8331065 Amir_6845 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104487.1 7981470 D 446462 CDS YP_003104488.1 256380828 8331066 complement(7981923..7983773) 1 NC_013093.1 PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bid:Bind_2834 thiamine pyrophosphate protein central region; thiamine pyrophosphate protein 7983773 8331066 Amir_6846 Actinosynnema mirum DSM 43827 thiamine pyrophosphate protein YP_003104488.1 7981923 R 446462 CDS YP_003104489.1 256380829 8331067 complement(7983770..7984648) 1 NC_013093.1 PFAM: Myo-inositol catabolism IolB domain protein; KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein; Myo-inositol catabolism IolB domain-containing protein 7984648 8331067 Amir_6847 Actinosynnema mirum DSM 43827 Myo-inositol catabolism IolB domain-containing protein YP_003104489.1 7983770 R 446462 CDS YP_003104490.1 256380830 8331068 complement(7984722..7985693) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: sus:Acid_1481 ribokinase-like domain- containing protein; PfkB domain-containing protein 7985693 8331068 Amir_6848 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003104490.1 7984722 R 446462 CDS YP_003104491.1 256380831 8331069 complement(7985690..7986457) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcs:BCAN_A1367 hypothetical protein; ABC transporter 7986457 8331069 Amir_6849 Actinosynnema mirum DSM 43827 ABC transporter YP_003104491.1 7985690 R 446462 CDS YP_003104492.1 256380832 8331070 complement(7986454..7987494) 1 NC_013093.1 PFAM: inner-membrane translocator; KEGG: acr:Acry_2317 inner-membrane translocator; Monosaccharide-transporting ATPase 7987494 8331070 Amir_6850 Actinosynnema mirum DSM 43827 Monosaccharide-transporting ATPase YP_003104492.1 7986454 R 446462 CDS YP_003104493.1 256380833 8331071 complement(7987500..7988507) 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: acr:Acry_2318 ABC-type sugar transport system periplasmic component-like protein; LacI family transcriptional regulator 7988507 8331071 Amir_6851 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003104493.1 7987500 R 446462 CDS YP_003104494.1 256380834 8331072 complement(7988569..7989423) 1 NC_013093.1 PFAM: xylose isomerase; KEGG: sit:TM1040_3346 xylose isomerase-like TIM barrel; xylose isomerase 7989423 8331072 Amir_6852 Actinosynnema mirum DSM 43827 xylose isomerase YP_003104494.1 7988569 R 446462 CDS YP_003104495.1 256380835 8331073 complement(7989420..7990436) 1 NC_013093.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: bbt:BBta_0488 inositol 2-dehydrogenase; inositol 2-dehydrogenase 7990436 8331073 Amir_6853 Actinosynnema mirum DSM 43827 inositol 2-dehydrogenase YP_003104495.1 7989420 R 446462 CDS YP_003104496.1 256380836 8331074 7990575..7991567 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: pmr:PMI0088 ribose operon repressor (LacI- family transcriptional regulator); LacI family transcriptional regulator 7991567 8331074 Amir_6854 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003104496.1 7990575 D 446462 CDS YP_003104497.1 256380837 8331075 complement(7992407..7992820) 1 NC_013093.1 PFAM: Class I peptide chain release factor; KEGG: rpi:Rpic_3102 class I peptide chain release factor; peptidyl-tRNA hydrolase domain-containing protein 7992820 8331075 Amir_6855 Actinosynnema mirum DSM 43827 peptidyl-tRNA hydrolase domain-containing protein YP_003104497.1 7992407 R 446462 CDS YP_003104498.1 256380838 8331076 complement(7992852..7993388) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 7993388 8331076 Amir_6856 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104498.1 7992852 R 446462 CDS YP_003104499.1 256380839 8331077 complement(7993385..7994209) 1 NC_013093.1 SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 7994209 8331077 Amir_6857 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003104499.1 7993385 R 446462 CDS YP_003104500.1 256380840 8331078 complement(7994557..7995630) 1 NC_013093.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 7995630 8331078 Amir_6858 Actinosynnema mirum DSM 43827 phosphoribosylaminoimidazole synthetase YP_003104500.1 7994557 R 446462 CDS YP_003104501.1 256380841 8331079 complement(7995633..7997210) 1 NC_013093.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 7997210 8331079 Amir_6859 Actinosynnema mirum DSM 43827 amidophosphoribosyltransferase YP_003104501.1 7995633 R 446462 CDS YP_003104502.1 256380842 8331080 complement(7997279..7998022) 1 NC_013093.1 PFAM: protein of unknown function DUF1503; hypothetical protein 7998022 8331080 Amir_6860 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104502.1 7997279 R 446462 CDS YP_003104503.1 256380843 8331081 7998232..7998546 1 NC_013093.1 hypothetical protein 7998546 8331081 Amir_6861 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104503.1 7998232 D 446462 CDS YP_003104504.1 256380844 8331082 7998543..8000507 1 NC_013093.1 PFAM: protein of unknown function DUF1023; KEGG: xca:xccb100_3697 outer membrane adhesin; hypothetical protein 8000507 8331082 Amir_6862 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104504.1 7998543 D 446462 CDS YP_003104505.1 256380845 8331083 complement(8000547..8000885) 1 NC_013093.1 hypothetical protein 8000885 8331083 Amir_6863 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104505.1 8000547 R 446462 CDS YP_003104506.1 256380846 8331084 complement(8000937..8001272) 1 NC_013093.1 hypothetical protein 8001272 8331084 Amir_6864 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104506.1 8000937 R 446462 CDS YP_003104507.1 256380847 8331085 complement(8001309..8001686) 1 NC_013093.1 hypothetical protein 8001686 8331085 Amir_6865 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104507.1 8001309 R 446462 CDS YP_003104508.1 256380848 8331086 complement(8001696..8002514) 1 NC_013093.1 hypothetical protein 8002514 8331086 Amir_6866 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104508.1 8001696 R 446462 CDS YP_003104509.1 256380849 8331087 complement(8002599..8004083) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 8004083 8331087 Amir_6867 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104509.1 8002599 R 446462 CDS YP_003104510.1 256380850 8331088 complement(8004100..8004492) 1 NC_013093.1 hypothetical protein 8004492 8331088 Amir_6868 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104510.1 8004100 R 446462 CDS YP_003104511.1 256380851 8331089 complement(8004611..8005225) 1 NC_013093.1 hypothetical protein 8005225 8331089 Amir_6869 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104511.1 8004611 R 446462 CDS YP_003104512.1 256380852 8331090 8005343..8006374 1 NC_013093.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: scl:sce1528 glucose 1-dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 8006374 8331090 Amir_6870 Actinosynnema mirum DSM 43827 alcohol dehydrogenase GroES domain-containing protein YP_003104512.1 8005343 D 446462 CDS YP_003104513.1 256380853 8331091 complement(8006391..8008553) 1 NC_013093.1 KEGG: gsu:GSU0474 sensory box/GGDEF family protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 8008553 8331091 Amir_6871 Actinosynnema mirum DSM 43827 PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase YP_003104513.1 8006391 R 446462 CDS YP_003104514.1 256380854 8331092 8008889..8009977 1 NC_013093.1 KEGG: predicted protein; hypothetical protein 8009977 8331092 Amir_6872 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104514.1 8008889 D 446462 CDS YP_003104515.1 256380855 8331094 8011169..8012017 1 NC_013093.1 KEGG: N,O-diacetylmuramidase; PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; lysozyme 8012017 8331094 Amir_6874 Actinosynnema mirum DSM 43827 lysozyme YP_003104515.1 8011169 D 446462 CDS YP_003104516.1 256380856 8331095 8012143..8012931 1 NC_013093.1 KEGG: N,O-diacetyl muramidase; K01238; PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; lysozyme 8012931 8331095 Amir_6875 Actinosynnema mirum DSM 43827 lysozyme YP_003104516.1 8012143 D 446462 CDS YP_003104517.1 256380857 8331096 complement(8012996..8015254) 1 NC_013093.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 8015254 8331096 Amir_6876 Actinosynnema mirum DSM 43827 phosphoribosylformylglycinamidine synthase II YP_003104517.1 8012996 R 446462 CDS YP_003104518.1 256380858 8331097 complement(8015251..8015922) 1 NC_013093.1 TIGRFAM: phosphoribosylformylglycinamidine synthase I; KEGG: afw:Anae109_3954 phosphoribosylformylglycinamidine synthase I; phosphoribosylformylglycinamidine synthase I 8015922 8331097 Amir_6877 Actinosynnema mirum DSM 43827 phosphoribosylformylglycinamidine synthase I YP_003104518.1 8015251 R 446462 CDS YP_003104519.1 256380859 8331098 complement(8015919..8016158) 1 NC_013093.1 TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS; KEGG: eli:ELI_02445 phosphoribosylformylglycinamidine synthase small subunit; phosphoribosylformylglycinamidine synthase PurS 8016158 8331098 Amir_6878 Actinosynnema mirum DSM 43827 phosphoribosylformylglycinamidine synthase PurS YP_003104519.1 8015919 R 446462 CDS YP_003104520.1 256380860 8331099 complement(8016387..8016929) 1 NC_013093.1 hypothetical protein 8016929 8331099 Amir_6879 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104520.1 8016387 R 446462 CDS YP_003104521.1 256380861 8331100 8017050..8018024 1 NC_013093.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: bja:blr6721 reductase; NAD-dependent epimerase/dehydratase 8018024 8331100 Amir_6880 Actinosynnema mirum DSM 43827 NAD-dependent epimerase/dehydratase YP_003104521.1 8017050 D 446462 CDS YP_003104522.1 256380862 8331101 8018150..8018773 1 NC_013093.1 PFAM: beta-lactamase domain protein; KEGG: acr:Acry_1778 hydroxyacylglutathione hydrolase; beta-lactamase domain-containing protein 8018773 8331101 Amir_6881 Actinosynnema mirum DSM 43827 beta-lactamase domain-containing protein YP_003104522.1 8018150 D 446462 CDS YP_003104523.1 256380863 8331102 complement(8018744..8019403) 1 NC_013093.1 KEGG: eba:ebA6939 hypothetical protein; deacetylase-like protein 8019403 8331102 Amir_6882 Actinosynnema mirum DSM 43827 deacetylase-like protein YP_003104523.1 8018744 R 446462 CDS YP_003104524.1 256380864 8331103 complement(8019558..8020445) 1 NC_013093.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 8020445 8331103 Amir_6883 Actinosynnema mirum DSM 43827 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_003104524.1 8019558 R 446462 CDS YP_003104525.1 256380865 8331104 8020509..8021366 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: rde:RD1_2182 amino acid ABC transporter, periplasmic-binding protein; family 3 extracellular solute-binding protein 8021366 8331104 Amir_6884 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003104525.1 8020509 D 446462 CDS YP_003104526.1 256380866 8331105 8021363..8022223 1 NC_013093.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_2183 glutamine ABC transporter, permease protein; polar amino acid ABC transporter, inner membrane subunit 8022223 8331105 Amir_6885 Actinosynnema mirum DSM 43827 polar amino acid ABC transporter, inner membrane subunit YP_003104526.1 8021363 D 446462 CDS YP_003104527.1 256380867 8331106 8022220..8022984 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mes:Meso_3147 ABC transporter; ABC transporter 8022984 8331106 Amir_6886 Actinosynnema mirum DSM 43827 ABC transporter YP_003104527.1 8022220 D 446462 CDS YP_003104528.1 256380868 8331107 8023065..8023544 1 NC_013093.1 KEGG: similar to C25F9.2; hypothetical protein 8023544 8331107 Amir_6887 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104528.1 8023065 D 446462 CDS YP_003104529.1 256380869 8331108 complement(8023612..8025042) 1 NC_013093.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 8025042 8331108 Amir_6888 Actinosynnema mirum DSM 43827 adenylosuccinate lyase YP_003104529.1 8023612 R 446462 CDS YP_003104530.1 256380870 8331109 complement(8025056..8025847) 1 NC_013093.1 hypothetical protein 8025847 8331109 Amir_6889 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104530.1 8025056 R 446462 CDS YP_003104531.1 256380871 8331110 complement(8025844..8026371) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: sus:Acid_7940 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 8026371 8331110 Amir_6890 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003104531.1 8025844 R 446462 CDS YP_003104532.1 256380872 8331111 complement(8026418..8027008) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: scl:sce1385 TetR family transcriptional regulator; TetR family transcriptional regulator 8027008 8331111 Amir_6891 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104532.1 8026418 R 446462 CDS YP_003104533.1 256380873 8331112 complement(8027064..8027825) 1 NC_013093.1 KEGG: GK23094 gene product from transcript GK23094- RA; hypothetical protein 8027825 8331112 Amir_6892 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104533.1 8027064 R 446462 CDS YP_003104534.1 256380874 8331113 complement(8027863..8028378) 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: pca:Pcar_3124 RNA polymerase, sigma-E factor; ECF subfamily RNA polymerase sigma-24 subunit 8028378 8331113 Amir_6893 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003104534.1 8027863 R 446462 CDS YP_003104535.1 256380875 8331114 8028531..8029550 1 NC_013093.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mxa:MXAN_1432 L-allo-threonine aldolase; aromatic amino acid beta-eliminating lyase/threonine aldolase 8029550 8331114 Amir_6894 Actinosynnema mirum DSM 43827 aromatic amino acid beta-eliminating lyase/threonine aldolase YP_003104535.1 8028531 D 446462 CDS YP_003104536.1 256380876 8331115 8029555..8030142 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: aba:Acid345_0142 HAD-superfamily hydrolase subfamily IA, variant 3; HAD superfamily hydrolase 8030142 8331115 Amir_6895 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003104536.1 8029555 D 446462 CDS YP_003104537.1 256380877 8331116 complement(8030251..8030403) 1 NC_013093.1 hypothetical protein 8030403 8331116 Amir_6896 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104537.1 8030251 R 446462 CDS YP_003104538.1 256380878 8331117 complement(8030410..8031576) 1 NC_013093.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 8031576 8331117 Amir_6897 Actinosynnema mirum DSM 43827 aspartate aminotransferase YP_003104538.1 8030410 R 446462 CDS YP_003104539.1 256380879 8331118 complement(8031586..8032116) 1 NC_013093.1 hypothetical protein 8032116 8331118 Amir_6898 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104539.1 8031586 R 446462 CDS YP_003104540.1 256380880 8331119 complement(8032236..8033012) 1 NC_013093.1 KEGG: ret:RHE_PE00455 sulfite reductase, beta subunit (hemoprotein) protein; hypothetical protein 8033012 8331119 Amir_6899 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104540.1 8032236 R 446462 CDS YP_003104541.1 256380881 8331120 complement(8033009..8034322) 1 NC_013093.1 KEGG: Os03g0309300; hypothetical protein; hypothetical protein 8034322 8331120 Amir_6900 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104541.1 8033009 R 446462 CDS YP_003104542.1 256380882 8331121 complement(8034335..8034937) 1 NC_013093.1 hypothetical protein 8034937 8331121 Amir_6901 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104542.1 8034335 R 446462 CDS YP_003104543.1 256380883 8331122 complement(8034927..8035277) 1 NC_013093.1 hypothetical protein 8035277 8331122 Amir_6902 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104543.1 8034927 R 446462 CDS YP_003104544.1 256380884 8331123 complement(8035608..8036867) 1 NC_013093.1 KEGG: ccs:CCNA_00299 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; phosphoribosylamine/glycine ligase 8036867 8331123 Amir_6903 Actinosynnema mirum DSM 43827 phosphoribosylamine/glycine ligase YP_003104544.1 8035608 R 446462 CDS YP_003104545.1 256380885 8331124 complement(8036896..8037885) 1 NC_013093.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: bpt:Bpet4159 hypothetical protein; TRAP transporter solute receptor, TAXI family 8037885 8331124 Amir_6904 Actinosynnema mirum DSM 43827 TRAP transporter solute receptor, TAXI family YP_003104545.1 8036896 R 446462 CDS YP_003104546.1 256380886 8331125 complement(8037878..8039926) 1 NC_013093.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; Citrate transporter; KEGG: bpt:Bpet4158 hypothetical protein; TRAP transporter, 4TM/12TM fusion protein 8039926 8331125 Amir_6905 Actinosynnema mirum DSM 43827 TRAP transporter, 4TM/12TM fusion protein YP_003104546.1 8037878 R 446462 CDS YP_003104547.1 256380887 8331126 8040106..8041251 1 NC_013093.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: rce:RC1_0289 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 8041251 8331126 Amir_6906 Actinosynnema mirum DSM 43827 glycerophosphoryl diester phosphodiesterase YP_003104547.1 8040106 D 446462 CDS YP_003104548.1 256380888 8331127 complement(8041402..8042544) 1 NC_013093.1 PFAM: luciferase-like monooxygenase; KEGG: alkanesulfonate monooxygenase; Alkanesulfonate monooxygenase 8042544 8331127 Amir_6907 Actinosynnema mirum DSM 43827 Alkanesulfonate monooxygenase YP_003104548.1 8041402 R 446462 CDS YP_003104549.1 256380889 8331128 complement(8042834..8044123) 1 NC_013093.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 8044123 8331128 Amir_6908 Actinosynnema mirum DSM 43827 adenylosuccinate synthetase YP_003104549.1 8042834 R 446462 CDS YP_003104550.1 256380890 8331129 8044218..8044889 1 NC_013093.1 hypothetical protein 8044889 8331129 Amir_6909 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104550.1 8044218 D 446462 CDS YP_003104551.1 256380891 8331130 8045008..8045646 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 8045646 8331130 Amir_6910 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104551.1 8045008 D 446462 CDS YP_003104552.1 256380892 8331131 8045646..8045897 1 NC_013093.1 hypothetical protein 8045897 8331131 Amir_6911 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104552.1 8045646 D 446462 CDS YP_003104553.1 256380893 8331132 8045952..8046938 1 NC_013093.1 PFAM: glycoside hydrolase family 16; KEGG: hch:HCH_06576 hypothetical protein; glycoside hydrolase family protein 8046938 8331132 Amir_6912 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003104553.1 8045952 D 446462 CDS YP_003104554.1 256380894 8331133 complement(8047101..8047364) 1 NC_013093.1 KEGG: son:SO_3323 acetyltransferase; hypothetical protein 8047364 8331133 Amir_6913 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104554.1 8047101 R 446462 CDS YP_003104555.1 256380895 8331134 complement(8047983..8049062) 1 NC_013093.1 KEGG: dac:Daci_3973 hypothetical protein; hypothetical protein 8049062 8331134 Amir_6914 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104555.1 8047983 R 446462 CDS YP_003104556.1 256380896 8331135 complement(8049076..8049489) 1 NC_013093.1 hypothetical protein 8049489 8331135 Amir_6915 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104556.1 8049076 R 446462 CDS YP_003104557.1 256380897 8331136 complement(8049496..8049591) 1 NC_013093.1 hypothetical protein 8049591 8331136 Amir_6916 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104557.1 8049496 R 446462 CDS YP_003104558.1 256380898 8331137 complement(8049811..8050845) 1 NC_013093.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 8050845 8331137 Amir_6917 Actinosynnema mirum DSM 43827 fructose-bisphosphate aldolase YP_003104558.1 8049811 R 446462 CDS YP_003104559.1 256380899 8331138 8050940..8051224 1 NC_013093.1 PFAM: protein of unknown function DUF427; KEGG: pnu:Pnuc_1659 hypothetical protein; hypothetical protein 8051224 8331138 Amir_6918 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104559.1 8050940 D 446462 CDS YP_003104560.1 256380900 8331139 8051373..8052311 1 NC_013093.1 PFAM: aldo/keto reductase; KEGG: ank:AnaeK_0485 aldo/keto reductase; aldo/keto reductase 8052311 8331139 Amir_6919 Actinosynnema mirum DSM 43827 aldo/keto reductase YP_003104560.1 8051373 D 446462 CDS YP_003104561.1 256380901 8331140 8052383..8053312 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bch:Bcen2424_6846 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 8053312 8331140 Amir_6920 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003104561.1 8052383 D 446462 CDS YP_003104562.1 256380902 8331141 complement(8053335..8053622) 1 NC_013093.1 PFAM: YCII-related; KEGG: reu:Reut_B5221 YCII-related; YCII-like protein 8053622 8331141 Amir_6921 Actinosynnema mirum DSM 43827 YCII-like protein YP_003104562.1 8053335 R 446462 CDS YP_003104563.1 256380903 8331142 8053686..8054264 1 NC_013093.1 TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: mxa:MXAN_2500 RNA polymerase sigma-70 factor, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 8054264 8331142 Amir_6922 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003104563.1 8053686 D 446462 CDS YP_003104564.1 256380904 8331143 8054467..8055366 1 NC_013093.1 PFAM: ROK family protein; KEGG: scl:sce7667 ROK family transcriptional regulator; ROK family protein 8055366 8331143 Amir_6923 Actinosynnema mirum DSM 43827 ROK family protein YP_003104564.1 8054467 D 446462 CDS YP_003104565.1 256380905 8331144 8055363..8056520 1 NC_013093.1 KEGG: smt:Smal_3421 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase 8056520 8331144 Amir_6924 Actinosynnema mirum DSM 43827 N-acetylglucosamine-6-phosphate deacetylase YP_003104565.1 8055363 D 446462 CDS YP_003104566.1 256380906 8331145 8056549..8057331 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 8057331 8331145 Amir_6925 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104566.1 8056549 D 446462 CDS YP_003104567.1 256380907 8331146 8057341..8058090 1 NC_013093.1 PFAM: hypothetical protein; KEGG: pfo:Pfl01_4994 hypothetical protein; hypothetical protein 8058090 8331146 Amir_6926 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104567.1 8057341 D 446462 CDS YP_003104568.1 256380908 8331147 complement(8058097..8059482) 1 NC_013093.1 PFAM: FAD linked oxidase domain protein; KEGG: scl:sce0752 glycolate oxidase; FAD linked oxidase domain-containing protein 8059482 8331147 Amir_6927 Actinosynnema mirum DSM 43827 FAD linked oxidase domain-containing protein YP_003104568.1 8058097 R 446462 CDS YP_003104569.1 256380909 8331148 8059601..8060275 1 NC_013093.1 PFAM: hypothetical protein; KEGG: plu:plu3172 hypothetical protein; hypothetical protein 8060275 8331148 Amir_6928 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104569.1 8059601 D 446462 CDS YP_003104570.1 256380910 8331149 complement(8060306..8060941) 1 NC_013093.1 KEGG: dac:Daci_0781 hypothetical protein; hypothetical protein 8060941 8331149 Amir_6929 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104570.1 8060306 R 446462 CDS YP_003104571.1 256380911 8331150 complement(8060923..8061864) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: sfu:Sfum_3386 PfkB domain protein; PfkB domain-containing protein 8061864 8331150 Amir_6930 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003104571.1 8060923 R 446462 CDS YP_003104572.1 256380912 8331151 8061943..8062890 1 NC_013093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: acr:Acry_0501 periplasmic binding protein/LacI transcriptional regulator; LacI family transcriptional regulator 8062890 8331151 Amir_6931 Actinosynnema mirum DSM 43827 LacI family transcriptional regulator YP_003104572.1 8061943 D 446462 CDS YP_003104573.1 256380913 8331152 complement(8062919..8064034) 1 NC_013093.1 PFAM: glycoside hydrolase family 76; KEGG: hypothetical protein; glycoside hydrolase family protein 8064034 8331152 Amir_6932 Actinosynnema mirum DSM 43827 glycoside hydrolase family protein YP_003104573.1 8062919 R 446462 CDS YP_003104574.1 256380914 8331153 complement(8064053..8064760) 1 NC_013093.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: azo:azo1893 RNA methyltransferase; tRNA/rRNA methyltransferase SpoU 8064760 8331153 Amir_6933 Actinosynnema mirum DSM 43827 tRNA/rRNA methyltransferase SpoU YP_003104574.1 8064053 R 446462 CDS YP_003104575.1 256380915 8331154 complement(8064832..8065221) 1 NC_013093.1 KEGG: eba:ebB138 hypothetical protein; hypothetical protein 8065221 8331154 Amir_6934 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104575.1 8064832 R 446462 CDS YP_003104576.1 256380916 8331155 complement(8065297..8066007) 1 NC_013093.1 hypothetical protein 8066007 8331155 Amir_6935 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104576.1 8065297 R 446462 CDS YP_003104577.1 256380917 8331156 complement(8066009..8066563) 1 NC_013093.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 8066563 pyrE 8331156 pyrE Actinosynnema mirum DSM 43827 orotate phosphoribosyltransferase YP_003104577.1 8066009 R 446462 CDS YP_003104578.1 256380918 8331157 8066630..8067184 1 NC_013093.1 hypothetical protein 8067184 8331157 Amir_6937 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104578.1 8066630 D 446462 CDS YP_003104579.1 256380919 8331158 complement(8067217..8067621) 1 NC_013093.1 hypothetical protein 8067621 8331158 Amir_6938 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104579.1 8067217 R 446462 CDS YP_003104580.1 256380920 8331159 complement(8067618..8068526) 1 NC_013093.1 hypothetical protein 8068526 8331159 Amir_6939 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104580.1 8067618 R 446462 CDS YP_003104581.1 256380921 8331160 complement(8068523..8068876) 1 NC_013093.1 hypothetical protein 8068876 8331160 Amir_6940 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104581.1 8068523 R 446462 CDS YP_003104582.1 256380922 8331161 complement(8069021..8069800) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: azc:AZC_1379 short-chain dehydrogenase; short-chain dehydrogenase/reductase SDR 8069800 8331161 Amir_6941 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003104582.1 8069021 R 446462 CDS YP_003104583.1 256380923 8331162 complement(8069797..8070501) 1 NC_013093.1 hypothetical protein 8070501 8331162 Amir_6942 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104583.1 8069797 R 446462 CDS YP_003104584.1 256380924 8331163 complement(8070630..8073212) 1 NC_013093.1 KEGG: ank:AnaeK_0413 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA; ATPase AAA; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA; ATP-dependent chaperone ClpB 8073212 8331163 Amir_6943 Actinosynnema mirum DSM 43827 ATP-dependent chaperone ClpB YP_003104584.1 8070630 R 446462 CDS YP_003104585.1 256380925 8331164 8073413..8073808 1 NC_013093.1 KEGG: rle:RL3033 hypothetical protein; hypothetical protein 8073808 8331164 Amir_6944 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104585.1 8073413 D 446462 CDS YP_003104586.1 256380926 8331165 8074275..8075378 1 NC_013093.1 PFAM: oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; globin; KEGG: afr:AFE_0860 iron-sulfur cluster-binding protein/oxidoreductase, FAD/NAD-binding; oxidoreductase FAD-binding domain-containing protein 8075378 8331165 Amir_6945 Actinosynnema mirum DSM 43827 oxidoreductase FAD-binding domain-containing protein YP_003104586.1 8074275 D 446462 CDS YP_003104587.1 256380927 8331166 complement(8075838..8076269) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: cjj:CJJ81176_1244 MerR family transcriptional regulator; MerR family transcriptional regulator 8076269 8331166 Amir_6946 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003104587.1 8075838 R 446462 CDS YP_003104588.1 256380928 8331167 complement(8076266..8077462) 1 NC_013093.1 KEGG: pag:PLES_51451 DnaJ protein; TIGRFAM: chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; chaperone protein DnaJ 8077462 8331167 Amir_6947 Actinosynnema mirum DSM 43827 chaperone protein DnaJ YP_003104588.1 8076266 R 446462 CDS YP_003104589.1 256380929 8331168 complement(8077483..8078136) 1 NC_013093.1 PFAM: GrpE protein; KEGG: dvm:DvMF_1194 GrpE protein; GrpE protein 8078136 8331168 Amir_6948 Actinosynnema mirum DSM 43827 GrpE protein YP_003104589.1 8077483 R 446462 CDS YP_003104590.1 256380930 8331169 complement(8078133..8079992) 1 NC_013093.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 8079992 dnaK 8331169 dnaK Actinosynnema mirum DSM 43827 molecular chaperone DnaK YP_003104590.1 8078133 R 446462 CDS YP_003104591.1 256380931 8331170 complement(8080207..8081013) 1 NC_013093.1 KEGG: aba:Acid345_3530 hypothetical protein; hypothetical protein 8081013 8331170 Amir_6950 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104591.1 8080207 R 446462 CDS YP_003104592.1 256380932 8331171 complement(8081179..8081754) 1 NC_013093.1 hypothetical protein 8081754 8331171 Amir_6951 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104592.1 8081179 R 446462 CDS YP_003104593.1 256380933 8331172 complement(8081915..8082244) 1 NC_013093.1 PFAM: small multidrug resistance protein; KEGG: oan:Oant_2259 small multidrug resistance protein; small multidrug resistance protein 8082244 8331172 Amir_6952 Actinosynnema mirum DSM 43827 small multidrug resistance protein YP_003104593.1 8081915 R 446462 CDS YP_003104594.1 256380934 8331173 8082402..8084678 1 NC_013093.1 PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ade:Adeh_0008 hypothetical protein; hypothetical protein 8084678 8331173 Amir_6953 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104594.1 8082402 D 446462 CDS YP_003104595.1 256380935 8331174 complement(8084757..8085137) 1 NC_013093.1 PFAM: membrane protein of unknown function; KEGG: bmv:BMASAVP1_A3416 hypothetical protein; hypothetical protein 8085137 8331174 Amir_6954 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104595.1 8084757 R 446462 CDS YP_003104596.1 256380936 8331175 complement(8085172..8086362) 1 NC_013093.1 KEGG: dsh:Dshi_3592 Cna B domain-containing protein; hypothetical protein 8086362 8331175 Amir_6955 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104596.1 8085172 R 446462 CDS YP_003104597.1 256380937 8331176 complement(8086602..8087444) 1 NC_013093.1 KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein 8087444 8331176 Amir_6956 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104597.1 8086602 R 446462 CDS YP_003104598.1 256380938 8331177 complement(8087622..8088740) 1 NC_013093.1 KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein 8088740 8331177 Amir_6957 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104598.1 8087622 R 446462 CDS YP_003104599.1 256380939 8331178 complement(8088946..8090061) 1 NC_013093.1 TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: dsh:Dshi_3592 Cna B domain-containing protein; LPXTG-motif cell wall anchor domain-containing protein 8090061 8331178 Amir_6958 Actinosynnema mirum DSM 43827 LPXTG-motif cell wall anchor domain-containing protein YP_003104599.1 8088946 R 446462 CDS YP_003104600.1 256380940 8331179 complement(8090391..8091026) 1 NC_013093.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 8091026 dcd 8331179 dcd Actinosynnema mirum DSM 43827 deoxycytidine triphosphate deaminase YP_003104600.1 8090391 R 446462 CDS YP_003104601.1 256380941 8331181 8091736..8092320 1 NC_013093.1 KEGG: similar to involucrin repeat protein; hypothetical protein 8092320 8331181 Amir_6960 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104601.1 8091736 D 446462 CDS YP_003104602.1 256380942 8331182 complement(8092372..8093973) 1 NC_013093.1 PFAM: Na+/solute symporter; KEGG: vsp:VS_1257 sodium/glucose cotransporter; Na+/solute symporter 8093973 8331182 Amir_6961 Actinosynnema mirum DSM 43827 Na+/solute symporter YP_003104602.1 8092372 R 446462 CDS YP_003104603.1 256380943 8331183 8094222..8094926 1 NC_013093.1 PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; KEGG: xcv:XCV2187 two-component system LuxR family regulatory protein; LuxR family transcriptional regulator 8094926 8331183 Amir_6962 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003104603.1 8094222 D 446462 CDS YP_003104604.1 256380944 8331184 8095175..8097013 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mxa:MXAN_0422 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 8097013 8331184 Amir_6963 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003104604.1 8095175 D 446462 CDS YP_003104605.1 256380945 8331185 complement(8097110..8097853) 1 NC_013093.1 PFAM: protein of unknown function DUF1206; KEGG: afw:Anae109_1905 hypothetical protein; hypothetical protein 8097853 8331185 Amir_6964 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104605.1 8097110 R 446462 CDS YP_003104606.1 256380946 8331186 complement(8097981..8100659) 1 NC_013093.1 PFAM: VanW family protein; KEGG: bcb:BCB4264_A0642 vancomycin B-type resistance protein VanW; VanW family protein 8100659 8331186 Amir_6965 Actinosynnema mirum DSM 43827 VanW family protein YP_003104606.1 8097981 R 446462 CDS YP_003104607.1 256380947 8331187 complement(8100739..8101059) 1 NC_013093.1 PFAM: chaperonin Cpn10; KEGG: noc:Noc_2922 co-chaperonin GroES; chaperonin Cpn10 8101059 8331187 Amir_6966 Actinosynnema mirum DSM 43827 chaperonin Cpn10 YP_003104607.1 8100739 R 446462 CDS YP_003104608.1 256380948 8331188 complement(8101121..8102959) 1 NC_013093.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; NHL repeat containing protein; Redoxin domain protein; KEGG: haloacid dehalogenase-like hydrolase family protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 8102959 8331188 Amir_6967 Actinosynnema mirum DSM 43827 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_003104608.1 8101121 R 446462 CDS YP_003104609.1 256380949 8331189 complement(8103057..8103425) 1 NC_013093.1 hypothetical protein 8103425 8331189 Amir_6968 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104609.1 8103057 R 446462 CDS YP_003104610.1 256380950 8331190 complement(8103886..8104032) 1 NC_013093.1 hypothetical protein 8104032 8331190 Amir_6969 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104610.1 8103886 R 446462 CDS YP_003104611.1 256380951 8331191 8104288..8104953 1 NC_013093.1 PFAM: protein of unknown function DUF541; KEGG: bra:BRADO0381 hypothetical protein; hypothetical protein 8104953 8331191 Amir_6970 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104611.1 8104288 D 446462 CDS YP_003104612.1 256380952 8331192 complement(8105070..8106293) 1 NC_013093.1 PFAM: OmpA/MotB domain protein; KEGG: dsh:Dshi_3025 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein 8106293 8331192 Amir_6971 Actinosynnema mirum DSM 43827 OmpA/MotB domain-containing protein YP_003104612.1 8105070 R 446462 CDS YP_003104613.1 256380953 8331193 complement(8106378..8107643) 1 NC_013093.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 8107643 8331193 Amir_6972 Actinosynnema mirum DSM 43827 acetyl-CoA acetyltransferase YP_003104613.1 8106378 R 446462 CDS YP_003104614.1 256380954 8331194 8107725..8109197 1 NC_013093.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 8109197 fabG 8331194 fabG Actinosynnema mirum DSM 43827 3-ketoacyl-(acyl-carrier-protein) reductase YP_003104614.1 8107725 D 446462 CDS YP_003104615.1 256380955 8331195 8109197..8110000 1 NC_013093.1 PFAM: MaoC domain protein dehydratase; KEGG: abo:ABO_1719 MaoC like domain-containing protein; MaoC domain-containing protein dehydratase 8110000 8331195 Amir_6974 Actinosynnema mirum DSM 43827 MaoC domain-containing protein dehydratase YP_003104615.1 8109197 D 446462 CDS YP_003104616.1 256380956 8331198 complement(8111546..8112760) 1 NC_013093.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: afw:Anae109_2163 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein 8112760 8331198 Amir_6977 Actinosynnema mirum DSM 43827 acyl-CoA dehydrogenase domain-containing protein YP_003104616.1 8111546 R 446462 CDS YP_003104617.1 256380957 8331199 complement(8112762..8113400) 1 NC_013093.1 KEGG: hsdl2; Hydroxysteroid dehydrogenase-like protein 2; hypothetical protein 8113400 8331199 Amir_6978 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104617.1 8112762 R 446462 CDS YP_003104618.1 256380958 8331200 8113502..8114164 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: bav:BAV3196 TetR-family trasncriptional regulator; TetR family transcriptional regulator 8114164 8331200 Amir_6979 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104618.1 8113502 D 446462 CDS YP_003104619.1 256380959 8331201 complement(8114416..8115315) 1 NC_013093.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: sal:Sala_2443 MerR family transcriptional regulator; MerR family transcriptional regulator 8115315 8331201 Amir_6980 Actinosynnema mirum DSM 43827 MerR family transcriptional regulator YP_003104619.1 8114416 R 446462 CDS YP_003104620.1 256380960 8331202 complement(8115420..8116772) 1 NC_013093.1 PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bha:BH2653 branched-chain alpha-keto acid dehydrogenase subunit E2; hypothetical protein 8116772 8331202 Amir_6981 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104620.1 8115420 R 446462 CDS YP_003104621.1 256380961 8331203 complement(8116783..8117805) 1 NC_013093.1 PFAM: transketolase; transketolase; KEGG: afw:Anae109_1994 transketolase; transketolase 8117805 8331203 Amir_6982 Actinosynnema mirum DSM 43827 transketolase YP_003104621.1 8116783 R 446462 CDS YP_003104622.1 256380962 8331204 complement(8117805..8118998) 1 NC_013093.1 KEGG: gme:Gmet_2509 dehydrogenase, E1 component; TIGRFAM: pyruvate dehydrogenase (acetyl- transferring) E1 component, alpha subunit; PFAM: dehydrogenase E1 component; pyruvate dehydrogenase E1 component subunit alpha 8118998 8331204 Amir_6983 Actinosynnema mirum DSM 43827 pyruvate dehydrogenase E1 component subunit alpha YP_003104622.1 8117805 R 446462 CDS YP_003104623.1 256380963 8331205 8119338..8120747 1 NC_013093.1 PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: xca:xccb100_1378 hypothetical protein; peptidase M20 8120747 8331205 Amir_6984 Actinosynnema mirum DSM 43827 peptidase M20 YP_003104623.1 8119338 D 446462 CDS YP_003104624.1 256380964 8331206 8120931..8123618 1 NC_013093.1 KEGG: sus:Acid_7132 hypothetical protein; hypothetical protein 8123618 8331206 Amir_6985 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104624.1 8120931 D 446462 CDS YP_003104625.1 256380965 8331207 8123790..8124605 1 NC_013093.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: acr:Acry_0683 extracellular solute-binding protein; family 3 extracellular solute-binding protein 8124605 8331207 Amir_6986 Actinosynnema mirum DSM 43827 family 3 extracellular solute-binding protein YP_003104625.1 8123790 D 446462 CDS YP_003104626.1 256380966 8331208 8124672..8125508 1 NC_013093.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: acr:Acry_0684 polar amino acid ABC transporter, inner membrane subunit; polar amino acid ABC transporter, inner membrane subunit 8125508 8331208 Amir_6987 Actinosynnema mirum DSM 43827 polar amino acid ABC transporter, inner membrane subunit YP_003104626.1 8124672 D 446462 CDS YP_003104627.1 256380967 8331209 8125505..8126302 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: acr:Acry_0685 ABC transporter; ABC transporter 8126302 8331209 Amir_6988 Actinosynnema mirum DSM 43827 ABC transporter YP_003104627.1 8125505 D 446462 CDS YP_003104628.1 256380968 8331210 8126304..8128442 1 NC_013093.1 KEGG: rce:RC1_0389 hypothetical protein; hypothetical protein 8128442 8331210 Amir_6989 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104628.1 8126304 D 446462 CDS YP_003104629.1 256380969 8331211 8128546..8129391 1 NC_013093.1 KEGG: Os02g0127100; hypothetical protein; hypothetical protein 8129391 8331211 Amir_6990 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104629.1 8128546 D 446462 CDS YP_003104630.1 256380970 8331212 8129388..8130407 1 NC_013093.1 hypothetical protein 8130407 8331212 Amir_6991 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104630.1 8129388 D 446462 CDS YP_003104631.1 256380971 8331213 8130404..8131534 1 NC_013093.1 KEGG: mxa:MXAN_1088 serine-threonine protein kinase; hypothetical protein 8131534 8331213 Amir_6992 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104631.1 8130404 D 446462 CDS YP_003104632.1 256380972 8331214 8131665..8132345 1 NC_013093.1 KEGG: GL23092 gene product from transcript GL23092- RA; hypothetical protein 8132345 8331214 Amir_6993 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104632.1 8131665 D 446462 CDS YP_003104633.1 256380973 8331215 8133054..8134865 1 NC_013093.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 8134865 8331215 Amir_6994 Actinosynnema mirum DSM 43827 phosphoenolpyruvate carboxykinase YP_003104633.1 8133054 D 446462 CDS YP_003104634.1 256380974 8331216 complement(8135361..8136191) 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 8136191 8331216 Amir_6995 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104634.1 8135361 R 446462 CDS YP_003104635.1 256380975 8331217 complement(8136356..8137858) 1 NC_013093.1 KEGG: pap:PSPA7_0052 hypothetical protein; hypothetical protein 8137858 8331217 Amir_6996 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104635.1 8136356 R 446462 CDS YP_003104636.1 256380976 8331218 8138036..8138734 1 NC_013093.1 PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; KEGG: reu:Reut_A2447 GntR family transcriptional regulator; GntR family transcriptional regulator 8138734 8331218 Amir_6997 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003104636.1 8138036 D 446462 CDS YP_003104637.1 256380977 8331219 8138931..8139209 1 NC_013093.1 KEGG: bur:Bcep18194_A5681 hypothetical protein; hypothetical protein 8139209 8331219 Amir_6998 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104637.1 8138931 D 446462 CDS YP_003104638.1 256380978 8331220 8139206..8140855 1 NC_013093.1 PFAM: Na+/solute symporter; KEGG: bvi:Bcep1808_2427 Na+/solute symporter; Na+/solute symporter 8140855 8331220 Amir_6999 Actinosynnema mirum DSM 43827 Na+/solute symporter YP_003104638.1 8139206 D 446462 CDS YP_003104639.1 256380979 8331221 complement(8140833..8141759) 1 NC_013093.1 PFAM: ROK family protein; KEGG: mlo:mlr7234 glucose kinase; ROK family protein 8141759 8331221 Amir_7000 Actinosynnema mirum DSM 43827 ROK family protein YP_003104639.1 8140833 R 446462 CDS YP_003104640.1 256380980 8331223 8142133..8142999 1 NC_013093.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 8142999 8331223 Amir_7002 Actinosynnema mirum DSM 43827 XRE family transcriptional regulator YP_003104640.1 8142133 D 446462 CDS YP_003104641.1 256380981 8331224 8143000..8143254 1 NC_013093.1 PFAM: protein of unknown function DUF397; hypothetical protein 8143254 8331224 Amir_7003 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104641.1 8143000 D 446462 CDS YP_003104642.1 256380982 8331225 complement(8143229..8145061) 1 NC_013093.1 PFAM: GTP-binding protein HSR1-related; KEGG: mca:MCA1193 hypothetical protein; HSR1-like GTP-binding protein 8145061 8331225 Amir_7004 Actinosynnema mirum DSM 43827 HSR1-like GTP-binding protein YP_003104642.1 8143229 R 446462 CDS YP_003104643.1 256380983 8331226 complement(8145058..8145432) 1 NC_013093.1 KEGG: mno:Mnod_1146 GrpE protein; hypothetical protein 8145432 8331226 Amir_7005 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104643.1 8145058 R 446462 CDS YP_003104644.1 256380984 8331227 complement(8145429..8146922) 1 NC_013093.1 KEGG: cha:CHAB381_0860 GTP-binding protein; hypothetical protein 8146922 8331227 Amir_7006 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104644.1 8145429 R 446462 CDS YP_003104645.1 256380985 8331228 8147162..8147929 1 NC_013093.1 KEGG: Sfrs15; splicing factor, arginine/serine-rich 15; hypothetical protein 8147929 8331228 Amir_7007 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104645.1 8147162 D 446462 CDS YP_003104646.1 256380986 8331229 8148082..8149290 1 NC_013093.1 PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 8149290 8331229 Amir_7008 Actinosynnema mirum DSM 43827 histidine kinase YP_003104646.1 8148082 D 446462 CDS YP_003104647.1 256380987 8331230 8149340..8149996 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 8149996 8331230 Amir_7009 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003104647.1 8149340 D 446462 CDS YP_003104648.1 256380988 8331231 complement(8150042..8150950) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_3578 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 8150950 8331231 Amir_7010 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003104648.1 8150042 R 446462 CDS YP_003104649.1 256380989 8331232 complement(8151025..8151597) 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: eum:ECUMN_4825 regulator of macrolide 2'- phosphotransferase I; TetR family transcriptional regulator 8151597 8331232 Amir_7011 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104649.1 8151025 R 446462 CDS YP_003104650.1 256380990 8331233 8151683..8152468 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: mno:Mnod_7133 Cof-like hydrolase; HAD superfamily hydrolase 8152468 8331233 Amir_7012 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003104650.1 8151683 D 446462 CDS YP_003104651.1 256380991 8331234 8152577..8153338 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 8153338 8331234 Amir_7013 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104651.1 8152577 D 446462 CDS YP_003104652.1 256380992 8331235 complement(8153575..8154741) 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 8154741 8331235 Amir_7014 Actinosynnema mirum DSM 43827 histidine kinase YP_003104652.1 8153575 R 446462 CDS YP_003104653.1 256380993 8331236 8154911..8155009 1 NC_013093.1 hypothetical protein 8155009 8331236 Amir_7015 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104653.1 8154911 D 446462 CDS YP_003104654.1 256380994 8331237 complement(8155091..8155810) 1 NC_013093.1 KEGG: tgr:Tgr7_3237 tRNA (guanine-N(7)-)- methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; tRNA (guanine-N(7)-)-methyltransferase 8155810 8331237 Amir_7016 Actinosynnema mirum DSM 43827 tRNA (guanine-N(7)-)-methyltransferase YP_003104654.1 8155091 R 446462 CDS YP_003104655.1 256380995 8331238 complement(8155833..8156465) 1 NC_013093.1 hypothetical protein 8156465 8331238 Amir_7017 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104655.1 8155833 R 446462 CDS YP_003104656.1 256380996 8331239 8156699..8158042 1 NC_013093.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: hypothetical protein; peptidase S8/S53 subtilisin kexin sedolisin 8158042 8331239 Amir_7018 Actinosynnema mirum DSM 43827 peptidase S8/S53 subtilisin kexin sedolisin YP_003104656.1 8156699 D 446462 CDS YP_003104657.1 256380997 8331240 complement(8158201..8158974) 1 NC_013093.1 KEGG: esa:ESA_01546 hypothetical protein; hypothetical protein 8158974 8331240 Amir_7019 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104657.1 8158201 R 446462 CDS YP_003104658.1 256380998 8331241 complement(8158971..8159891) 1 NC_013093.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH0445 ABC transporter ATP-binding protein; ABC transporter 8159891 8331241 Amir_7020 Actinosynnema mirum DSM 43827 ABC transporter YP_003104658.1 8158971 R 446462 CDS YP_003104659.1 256380999 8331242 complement(8159888..8160004) 1 NC_013093.1 hypothetical protein 8160004 8331242 Amir_7021 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104659.1 8159888 R 446462 CDS YP_003104660.1 256381000 8331243 8160106..8160537 1 NC_013093.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: bja:blr4240 hypothetical protein; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 8160537 8331243 Amir_7022 Actinosynnema mirum DSM 43827 pyridoxamine 5'-phosphate oxidase-like FMN- binding protein YP_003104660.1 8160106 D 446462 CDS YP_003104661.1 256381001 8331244 complement(8160638..8160994) 1 NC_013093.1 hypothetical protein 8160994 8331244 Amir_7023 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104661.1 8160638 R 446462 CDS YP_003104662.1 256381002 8331245 8161086..8162390 1 NC_013093.1 PFAM: amidohydrolase; adenosine/AMP deaminase; Amidohydrolase 3; KEGG: tmz:Tmz1t_1721 amidohydrolase; amidohydrolase 8162390 8331245 Amir_7024 Actinosynnema mirum DSM 43827 amidohydrolase YP_003104662.1 8161086 D 446462 CDS YP_003104663.1 256381003 8331246 complement(8162471..8163160) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rce:RC1_3985 oxidoreductase, short chain dehydrogenase; short chain dehydrogenase 8163160 8331246 Amir_7025 Actinosynnema mirum DSM 43827 short chain dehydrogenase YP_003104663.1 8162471 R 446462 CDS YP_003104664.1 256381004 8331247 complement(8163343..8165433) 1 NC_013093.1 PFAM: protein of unknown function DUF839; KEGG: mes:Meso_0954 twin-arginine translocation pathway signal; hypothetical protein 8165433 8331247 Amir_7026 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104664.1 8163343 R 446462 CDS YP_003104665.1 256381005 8331248 complement(8165608..8167641) 1 NC_013093.1 PFAM: protein of unknown function DUF839; KEGG: noc:Noc_2144 hypothetical protein; hypothetical protein 8167641 8331248 Amir_7027 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104665.1 8165608 R 446462 CDS YP_003104666.1 256381006 8331249 complement(8167702..8168862) 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: rpc:RPC_3634 major facilitator transporter; major facilitator superfamily protein 8168862 8331249 Amir_7028 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003104666.1 8167702 R 446462 CDS YP_003104667.1 256381007 8331250 8168928..8169569 1 NC_013093.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: vei:Veis_2048 HAD-superfamily hydrolase, subfamily IA, variant 3; HAD superfamily hydrolase 8169569 8331250 Amir_7029 Actinosynnema mirum DSM 43827 HAD superfamily hydrolase YP_003104667.1 8168928 D 446462 CDS YP_003104668.1 256381008 8331251 8169686..8170414 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pna:Pnap_2712 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 8170414 8331251 Amir_7030 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003104668.1 8169686 D 446462 CDS YP_003104669.1 256381009 8331252 complement(8170546..8171637) 1 NC_013093.1 TIGRFAM: inositol 1-phosphate synthase; PFAM: Myo-inositol-1-phosphate synthase; Myo- inositol-1-phosphate synthase GAPDH domain protein; KEGG: sme:SM_b20249 myo-inositol-1- phosphate synthase; inositol 1-phosphate synthase 8171637 8331252 Amir_7031 Actinosynnema mirum DSM 43827 inositol 1-phosphate synthase YP_003104669.1 8170546 R 446462 CDS YP_003104670.1 256381010 8331253 complement(8171667..8172212) 1 NC_013093.1 PFAM: transcriptional regulator PadR family protein; KEGG: dal:Dalk_2104 transcriptional regulator, PadR- like family; PadR family transcriptional regulator 8172212 8331253 Amir_7032 Actinosynnema mirum DSM 43827 PadR family transcriptional regulator YP_003104670.1 8171667 R 446462 CDS YP_003104671.1 256381011 8331254 8172378..8172782 1 NC_013093.1 hypothetical protein 8172782 8331254 Amir_7033 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104671.1 8172378 D 446462 CDS YP_003104672.1 256381012 8331255 8173119..8175635 1 NC_013093.1 PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: bsu:BSU37510 hypothetical protein; glycosyl transferase family protein 8175635 8331255 Amir_7034 Actinosynnema mirum DSM 43827 glycosyl transferase family protein YP_003104672.1 8173119 D 446462 CDS YP_003104673.1 256381013 8331256 8175765..8177324 1 NC_013093.1 KEGG: ade:Adeh_0166 integral membrane protein-like; integral membrane protein 8177324 8331256 Amir_7035 Actinosynnema mirum DSM 43827 integral membrane protein YP_003104673.1 8175765 D 446462 CDS YP_003104674.1 256381014 8331257 complement(8177399..8178796) 1 NC_013093.1 KEGG: afw:Anae109_0175 integral membrane protein- like protein; integral membrane protein 8178796 8331257 Amir_7036 Actinosynnema mirum DSM 43827 integral membrane protein YP_003104674.1 8177399 R 446462 CDS YP_003104675.1 256381015 8331258 complement(8178793..8179563) 1 NC_013093.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 8179563 8331258 Amir_7037 Actinosynnema mirum DSM 43827 endonuclease IV YP_003104675.1 8178793 R 446462 CDS YP_003104676.1 256381016 8331259 8179740..8180720 1 NC_013093.1 KEGG: Taf4a; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor; K03129 transcription initiation factor TFIID subunit D3; TAF4A RNA polymerase II 8180720 8331259 Amir_7038 Actinosynnema mirum DSM 43827 TAF4A RNA polymerase II YP_003104676.1 8179740 D 446462 CDS YP_003104677.1 256381017 8331260 8180975..8181331 1 NC_013093.1 TIGRFAM: ribosomal protein S6; PFAM: ribosomal protein S6; KEGG: bcy:Bcer98_4014 30S ribosomal protein S6; 30S ribosomal protein S6 8181331 8331260 Amir_7039 Actinosynnema mirum DSM 43827 30S ribosomal protein S6 YP_003104677.1 8180975 D 446462 CDS YP_003104678.1 256381018 8331261 8181345..8181851 1 NC_013093.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bsu:BSU40900 single-strand DNA-binding protein; single-strand binding protein 8181851 8331261 Amir_7040 Actinosynnema mirum DSM 43827 single-strand binding protein YP_003104678.1 8181345 D 446462 CDS YP_003104679.1 256381019 8331262 8181903..8182142 1 NC_013093.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 8182142 rpsR 8331262 rpsR Actinosynnema mirum DSM 43827 30S ribosomal protein S18 YP_003104679.1 8181903 D 446462 CDS YP_003104680.1 256381020 8331263 8182162..8182617 1 NC_013093.1 TIGRFAM: ribosomal protein L9; PFAM: ribosomal protein L9; KEGG: bcb:BCB4264_A5596 ribosomal protein L9; 50S ribosomal protein L9 8182617 8331263 Amir_7042 Actinosynnema mirum DSM 43827 50S ribosomal protein L9 YP_003104680.1 8182162 D 446462 CDS YP_003104681.1 256381021 8331264 8183036..8185354 1 NC_013093.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; KEGG: bcm:Bcenmc03_1893 DnaB domain-containing protein; replicative DNA helicase 8185354 8331264 Amir_7043 Actinosynnema mirum DSM 43827 replicative DNA helicase YP_003104681.1 8183036 D 446462 CDS YP_003104682.1 256381022 8331265 8186032..8186406 1 NC_013093.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rru:Rru_A2907 anti-sigma-factor antagonist domain-containing protein; anti-sigma-factor antagonist 8186406 8331265 Amir_7044 Actinosynnema mirum DSM 43827 anti-sigma-factor antagonist YP_003104682.1 8186032 D 446462 CDS YP_003104683.1 256381023 8331266 complement(8186431..8187183) 1 NC_013093.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: nar:Saro_2963 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 8187183 8331266 Amir_7045 Actinosynnema mirum DSM 43827 short-chain dehydrogenase/reductase SDR YP_003104683.1 8186431 R 446462 CDS YP_003104684.1 256381024 8331267 8187270..8188106 1 NC_013093.1 SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 8188106 8331267 Amir_7046 Actinosynnema mirum DSM 43827 helix-turn-helix domain-containing protein YP_003104684.1 8187270 D 446462 CDS YP_003104685.1 256381025 8331268 8188123..8189271 1 NC_013093.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: rme:Rmet_3922 DNA polymerase III, epsilon subunit; exonuclease RNase T and DNA polymerase III 8189271 8331268 Amir_7047 Actinosynnema mirum DSM 43827 exonuclease RNase T and DNA polymerase III YP_003104685.1 8188123 D 446462 CDS YP_003104686.1 256381026 8331269 8189373..8190155 1 NC_013093.1 KEGG: pen:PSEEN1648 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 8190155 8331269 Amir_7048 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003104686.1 8189373 D 446462 CDS YP_003104687.1 256381027 8331270 complement(8190298..8193360) 1 NC_013093.1 KEGG: bch:Bcen2424_6767 outer membrane autotransporter; hypothetical protein 8193360 8331270 Amir_7049 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104687.1 8190298 R 446462 CDS YP_003104688.1 256381028 8331271 complement(8193537..8194379) 1 NC_013093.1 KEGG: GK21216 gene product from transcript GK21216- RA; hypothetical protein 8194379 8331271 Amir_7050 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104688.1 8193537 R 446462 CDS YP_003104689.1 256381029 8331272 complement(8194664..8197108) 1 NC_013093.1 KEGG: rce:RC1_0389 hypothetical protein; hypothetical protein 8197108 8331272 Amir_7051 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104689.1 8194664 R 446462 CDS YP_003104690.1 256381030 8331273 8197240..8198448 1 NC_013093.1 PFAM: protein of unknown function UPF0118; KEGG: mxa:MXAN_7270 hypothetical protein; hypothetical protein 8198448 8331273 Amir_7052 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104690.1 8197240 D 446462 CDS YP_003104691.1 256381031 8331274 complement(8198464..8199663) 1 NC_013093.1 KEGG: pca:Pcar_1107 two component signal transduction response regulator; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 8199663 8331274 Amir_7053 Actinosynnema mirum DSM 43827 diguanylate cyclase YP_003104691.1 8198464 R 446462 CDS YP_003104692.1 256381032 8331275 8199826..8200971 1 NC_013093.1 PFAM: ATP-binding region ATPase domain protein; KEGG: bpl:BURPS1106A_1352 membrane sensor histidine kinase; signal transduction histidine kinase 8200971 8331275 Amir_7054 Actinosynnema mirum DSM 43827 signal transduction histidine kinase YP_003104692.1 8199826 D 446462 CDS YP_003104693.1 256381033 8331276 8200968..8201627 1 NC_013093.1 PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: reh:H16_B2334 response regulator, NarL-family; LuxR family transcriptional regulator 8201627 8331276 Amir_7055 Actinosynnema mirum DSM 43827 LuxR family transcriptional regulator YP_003104693.1 8200968 D 446462 CDS YP_003104694.1 256381034 8331277 complement(8201666..8201773) 1 NC_013093.1 hypothetical protein 8201773 8331277 Amir_7056 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104694.1 8201666 R 446462 CDS YP_003104695.1 256381035 8331279 8202333..8202446 1 NC_013093.1 hypothetical protein 8202446 8331279 Amir_7058 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104695.1 8202333 D 446462 CDS YP_003104696.1 256381036 8331280 8202469..8203356 1 NC_013093.1 hypothetical protein 8203356 8331280 Amir_7059 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104696.1 8202469 D 446462 CDS YP_003104697.1 256381037 8331281 8203357..8203992 1 NC_013093.1 hypothetical protein 8203992 8331281 Amir_7060 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104697.1 8203357 D 446462 CDS YP_003104698.1 256381038 8331282 8203995..8204597 1 NC_013093.1 PFAM: protein of unknown function DUF1707; KEGG: swp:swp_3997 hypothetical protein; hypothetical protein 8204597 8331282 Amir_7061 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104698.1 8203995 D 446462 CDS YP_003104699.1 256381039 8331283 8204631..8206169 1 NC_013093.1 PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; dTDP-4- dehydrorhamnose reductase; KEGG: dvl:Dvul_2879 NAD-dependent epimerase/dehydratase; NmrA family protein 8206169 8331283 Amir_7062 Actinosynnema mirum DSM 43827 NmrA family protein YP_003104699.1 8204631 D 446462 CDS YP_003104700.1 256381040 8331284 8206231..8207265 1 NC_013093.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 8207265 tdh 8331284 tdh Actinosynnema mirum DSM 43827 L-threonine 3-dehydrogenase YP_003104700.1 8206231 D 446462 CDS YP_003104701.1 256381041 8331285 8207265..8208449 1 NC_013093.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 8208449 8331285 Amir_7064 Actinosynnema mirum DSM 43827 2-amino-3-ketobutyrate coenzyme A ligase YP_003104701.1 8207265 D 446462 CDS YP_003104702.1 256381042 8331286 8208534..8209418 1 NC_013093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pmy:Pmen_4546 LysR family transcriptional regulator; LysR family transcriptional regulator 8209418 8331286 Amir_7065 Actinosynnema mirum DSM 43827 LysR family transcriptional regulator YP_003104702.1 8208534 D 446462 CDS YP_003104703.1 256381043 8331287 complement(8209394..8209726) 1 NC_013093.1 hypothetical protein 8209726 8331287 Amir_7066 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104703.1 8209394 R 446462 CDS YP_003104704.1 256381044 8331288 complement(8210320..8211402) 1 NC_013093.1 KEGG: sfu:Sfum_3180 hypothetical protein; hypothetical protein 8211402 8331288 Amir_7067 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104704.1 8210320 R 446462 CDS YP_003104705.1 256381045 8331289 complement(8211547..8211978) 1 NC_013093.1 hypothetical protein 8211978 8331289 Amir_7068 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104705.1 8211547 R 446462 CDS YP_003104706.1 256381046 8331290 complement(8211993..8213624) 1 NC_013093.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: scl:sce2489 fructose-specific MTP; phosphoenolpyruvate-protein phosphotransferase 8213624 8331290 Amir_7069 Actinosynnema mirum DSM 43827 phosphoenolpyruvate-protein phosphotransferase YP_003104706.1 8211993 R 446462 CDS YP_003104707.1 256381047 8331291 complement(8213696..8214547) 1 NC_013093.1 PFAM: PfkB domain protein; KEGG: bmj:BMULJ_01615 ribokinase; PfkB domain-containing protein 8214547 8331291 Amir_7070 Actinosynnema mirum DSM 43827 PfkB domain-containing protein YP_003104707.1 8213696 R 446462 CDS YP_003104708.1 256381048 8331292 8214662..8216581 1 NC_013093.1 KEGG: mpo:Mpop_4712 hypothetical protein; hypothetical protein 8216581 8331292 Amir_7071 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104708.1 8214662 D 446462 CDS YP_003104709.1 256381049 8331293 complement(8216872..8219004) 1 NC_013093.1 PFAM: MMPL domain protein; KEGG: bcr:BCAH187_A1444 transporter; MMPL domain-containing protein 8219004 8331293 Amir_7072 Actinosynnema mirum DSM 43827 MMPL domain-containing protein YP_003104709.1 8216872 R 446462 CDS YP_003104710.1 256381050 8331294 8219133..8219879 1 NC_013093.1 PFAM: regulatory protein TetR; KEGG: mes:Meso_0701 transcriptional regulator, TetR family; TetR family transcriptional regulator 8219879 8331294 Amir_7073 Actinosynnema mirum DSM 43827 TetR family transcriptional regulator YP_003104710.1 8219133 D 446462 CDS YP_003104711.1 256381051 8331295 complement(8219961..8222765) 1 NC_013093.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 8222765 leuS 8331295 leuS Actinosynnema mirum DSM 43827 leucyl-tRNA synthetase YP_003104711.1 8219961 R 446462 CDS YP_003104712.1 256381052 8331296 8222941..8223471 1 NC_013093.1 KEGG: hypothetical protein; hypothetical protein 8223471 8331296 Amir_7075 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104712.1 8222941 D 446462 CDS YP_003104713.1 256381053 8331297 complement(8223494..8224075) 1 NC_013093.1 PFAM: protein of unknown function DUF179; KEGG: aeh:Mlg_0349 hypothetical protein; hypothetical protein 8224075 8331297 Amir_7076 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104713.1 8223494 R 446462 CDS YP_003104714.1 256381054 8331298 8224166..8225476 1 NC_013093.1 PFAM: major facilitator superfamily MFS_1; KEGG: bav:BAV0769 transporter; major facilitator superfamily protein 8225476 8331298 Amir_7077 Actinosynnema mirum DSM 43827 major facilitator superfamily protein YP_003104714.1 8224166 D 446462 CDS YP_003104715.1 256381055 8331300 complement(8225881..8227389) 1 NC_013093.1 KEGG: hypothetical protein; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; polynucleotide adenylyltransferase/metal dependent phosphohydrolase 8227389 8331300 Amir_7079 Actinosynnema mirum DSM 43827 polynucleotide adenylyltransferase/metal dependent phosphohydrolase YP_003104715.1 8225881 R 446462 CDS YP_003104716.1 256381056 8331301 8227525..8228049 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: mxa:MXAN_4891 hydrolase, NUDIX family; NUDIX hydrolase 8228049 8331301 Amir_7080 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003104716.1 8227525 D 446462 CDS YP_003104717.1 256381057 8331302 8228046..8230340 1 NC_013093.1 KEGG: ccs:CCNA_00415 hypothetical protein; hypothetical protein 8230340 8331302 Amir_7081 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104717.1 8228046 D 446462 CDS YP_003104718.1 256381058 8331303 8230406..8231971 1 NC_013093.1 PFAM: virulence factor MVIN family protein; KEGG: glo:Glov_2048 integral membrane protein MviN; virulence factor MVIN family protein 8231971 8331303 Amir_7082 Actinosynnema mirum DSM 43827 virulence factor MVIN family protein YP_003104718.1 8230406 D 446462 CDS YP_003104719.1 256381059 8331304 8232009..8233517 1 NC_013093.1 KEGG: azo:azo3774 serine/threonine protein kinase; hypothetical protein 8233517 8331304 Amir_7083 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104719.1 8232009 D 446462 CDS YP_003104720.1 256381060 8331305 8233657..8234268 1 NC_013093.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: sus:Acid_7940 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 8234268 8331305 Amir_7084 Actinosynnema mirum DSM 43827 ECF subfamily RNA polymerase sigma-24 subunit YP_003104720.1 8233657 D 446462 CDS YP_003104721.1 256381061 8331306 8234265..8235128 1 NC_013093.1 KEGG: mno:Mnod_6604 hypothetical protein; hypothetical protein 8235128 8331306 Amir_7085 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104721.1 8234265 D 446462 CDS YP_003104722.1 256381062 8331307 8235340..8236335 1 NC_013093.1 KEGG: acp:A2cp1_4094 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; thioredoxin reductase 8236335 8331307 Amir_7086 Actinosynnema mirum DSM 43827 thioredoxin reductase YP_003104722.1 8235340 D 446462 CDS YP_003104723.1 256381063 8331308 8236364..8236690 1 NC_013093.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: gdi:GDI0716 thioredoxin; thioredoxin 8236690 8331308 Amir_7087 Actinosynnema mirum DSM 43827 thioredoxin YP_003104723.1 8236364 D 446462 CDS YP_003104724.1 256381064 8331309 8236887..8238026 1 NC_013093.1 PFAM: cell wall hydrolase/autolysin; peptidoglycan- binding domain 1 protein; SMART: cell wall hydrolase/autolysin; KEGG: bha:BH3665 N-acetylmuramoyl-L-alanine amidase (major autolysin); cell wall hydrolase/autolysin 8238026 8331309 Amir_7088 Actinosynnema mirum DSM 43827 cell wall hydrolase/autolysin YP_003104724.1 8236887 D 446462 CDS YP_003104725.1 256381065 8331310 complement(8238152..8238784) 1 NC_013093.1 hypothetical protein 8238784 8331310 Amir_7089 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104725.1 8238152 R 446462 CDS YP_003104726.1 256381066 8331311 8238936..8240252 1 NC_013093.1 PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein; GntR family transcriptional regulator 8240252 8331311 Amir_7090 Actinosynnema mirum DSM 43827 GntR family transcriptional regulator YP_003104726.1 8238936 D 446462 CDS YP_003104727.1 256381067 8331312 8240266..8241210 1 NC_013093.1 PFAM: D-alanine--D-alanine ligase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP- grasp; KEGG: afw:Anae109_3887 D-alanine--D-alanine ligase; D-alanine--D-alanine ligase 8241210 8331312 Amir_7091 Actinosynnema mirum DSM 43827 D-alanine--D-alanine ligase YP_003104727.1 8240266 D 446462 CDS YP_003104728.1 256381068 8331313 complement(8241299..8242294) 1 NC_013093.1 KEGG: acp:A2cp1_4509 ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; parB-like partition protein 8242294 8331313 Amir_7092 Actinosynnema mirum DSM 43827 parB-like partition protein YP_003104728.1 8241299 R 446462 CDS YP_003104729.1 256381069 8331314 complement(8242291..8243310) 1 NC_013093.1 PFAM: cobyrinic acid ac-diamide synthase; KEGG: bsu:BSU40970 chromosome partitioning protein; transcriptional regulator; cobyrinic acid ac-diamide synthase 8243310 8331314 Amir_7093 Actinosynnema mirum DSM 43827 cobyrinic acid ac-diamide synthase YP_003104729.1 8242291 R 446462 CDS YP_003104730.1 256381070 8331315 complement(8243312..8243983) 1 NC_013093.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: cak:Caul_5025 methyltransferase GidB; methyltransferase GidB 8243983 8331315 Amir_7094 Actinosynnema mirum DSM 43827 methyltransferase GidB YP_003104730.1 8243312 R 446462 CDS YP_003104731.1 256381071 8331316 complement(8244537..8245004) 1 NC_013093.1 PFAM: NUDIX hydrolase; KEGG: bcr:BCAH187_A2810 MutT/NUDIX family protein; NUDIX hydrolase 8245004 8331316 Amir_7095 Actinosynnema mirum DSM 43827 NUDIX hydrolase YP_003104731.1 8244537 R 446462 CDS YP_003104732.1 256381072 8331317 complement(8245383..8245934) 1 NC_013093.1 PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: bha:BH4063 spoIIIJ-associated protein; single-stranded nucleic acid binding R3H domain-containing protein 8245934 8331317 Amir_7096 Actinosynnema mirum DSM 43827 single-stranded nucleic acid binding R3H domain-containing protein YP_003104732.1 8245383 R 446462 CDS YP_003104733.1 256381073 8331318 complement(8245963..8247039) 1 NC_013093.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: mmw:Mmwyl1_4485 60 kDa inner membrane insertion protein; 60 kDa inner membrane insertion protein 8247039 8331318 Amir_7097 Actinosynnema mirum DSM 43827 60 kDa inner membrane insertion protein YP_003104733.1 8245963 R 446462 CDS YP_003104734.1 256381074 8331319 complement(8247043..8247312) 1 NC_013093.1 PFAM: protein of unknown function DUF37; KEGG: ade:Adeh_4359 hypothetical protein; hypothetical protein 8247312 8331319 Amir_7098 Actinosynnema mirum DSM 43827 hypothetical protein YP_003104734.1 8247043 R 446462 CDS YP_003104735.1 256381075 8331320 complement(8247309..8247554) 1 NC_013093.1 PFAM: ribonuclease P protein; KEGG: sal:Sala_0006 ribonuclease P protein component; ribonuclease P protein 8247554 8331320 Amir_7099 Actinosynnema mirum DSM 43827 ribonuclease P protein YP_003104735.1 8247309 R 446462 CDS YP_003104736.1 256381076 8331321 complement(8247667..8247810) 1 NC_013093.1 TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; KEGG: aba:Acid345_0220 LSU ribosomal protein L34P; 50S ribosomal protein L34 8247810 8331321 Amir_7100 Actinosynnema mirum DSM 43827 50S ribosomal protein L34 YP_003104736.1 8247667 R 446462 CDS