-- dump date 20140618_191807 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 446462000001 SEQ_END SEQ_END NC_013093.1 8248144 8248144 DR NC_013093.1; contig end 8248144..8248144 Actinosynnema mirum DSM 43827 YP_003097821.1 CDS dnaA NC_013093.1 98 1831 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 98..1831 Actinosynnema mirum DSM 43827 8331322 YP_003097822.1 CDS Amir_0002 NC_013093.1 2628 3764 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2628..3764 Actinosynnema mirum DSM 43827 8324144 YP_003097823.1 CDS Amir_0003 NC_013093.1 3806 4720 D similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase-like protein 3806..4720 Actinosynnema mirum DSM 43827 8324145 YP_003097824.1 CDS recF NC_013093.1 4728 5843 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4728..5843 Actinosynnema mirum DSM 43827 8324146 YP_003097825.1 CDS Amir_0005 NC_013093.1 6031 6462 D PFAM: protein of unknown function DUF721; KEGG: protein of unknown function DUF721; hypothetical protein 6031..6462 Actinosynnema mirum DSM 43827 8324147 YP_003097826.1 CDS Amir_0006 NC_013093.1 6701 8674 D KEGG: bha:BH0006 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; DNA gyrase subunit B domain protein; TOPRIM domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; DNA gyrase subunit B 6701..8674 Actinosynnema mirum DSM 43827 8324148 YP_003097827.1 CDS Amir_0007 NC_013093.1 8721 11243 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 8721..11243 Actinosynnema mirum DSM 43827 8324149 YP_003097828.1 CDS Amir_0008 NC_013093.1 11278 12144 D KEGG: hypothetical protein; hypothetical protein 11278..12144 Actinosynnema mirum DSM 43827 8324150 YP_003097829.1 CDS Amir_0009 NC_013093.1 12309 12428 D hypothetical protein 12309..12428 Actinosynnema mirum DSM 43827 8324152 YP_003097830.1 CDS Amir_0010 NC_013093.1 12873 13304 R PFAM: DoxX family protein; KEGG: gur:Gura_3338 DoxX family protein; DoxX family protein complement(12873..13304) Actinosynnema mirum DSM 43827 8324154 YP_003097831.1 CDS Amir_0011 NC_013093.1 13441 13986 D KEGG: similar to Host cell factor C1; hypothetical protein 13441..13986 Actinosynnema mirum DSM 43827 8324155 YP_003097832.1 CDS Amir_0012 NC_013093.1 14069 14509 R KEGG: rpt:Rpal_3590 histon H1; hypothetical protein complement(14069..14509) Actinosynnema mirum DSM 43827 8324156 YP_003097833.1 CDS Amir_0013 NC_013093.1 14769 15317 D PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: bba:Bd0177 peptidyl-prolyl cis-trans isomerase; peptidylprolyl isomerase 14769..15317 Actinosynnema mirum DSM 43827 8324157 YP_003097834.1 CDS Amir_0014 NC_013093.1 15317 16213 D PFAM: rhomboid family protein; KEGG: bsu:BSU24870 hypothetical protein; rhomboid family protein 15317..16213 Actinosynnema mirum DSM 43827 8324158 YP_003097835.1 CDS Amir_0015 NC_013093.1 16463 16885 R hypothetical protein complement(16463..16885) Actinosynnema mirum DSM 43827 8324159 YP_003097836.1 CDS Amir_0016 NC_013093.1 17118 17384 R integral membrane protein involved in inhibition of the Z-ring formation; septation inhibitor protein complement(17118..17384) Actinosynnema mirum DSM 43827 8324160 YP_003097837.1 CDS Amir_0017 NC_013093.1 17775 18836 D TIGRFAM: sortase family protein; PFAM: peptidase C60 sortase A and B; KEGG: sus:Acid_5377 sortase family protein; sortase family protein 17775..18836 Actinosynnema mirum DSM 43827 8324161 YP_003097838.1 CDS Amir_0018 NC_013093.1 18838 18996 D hypothetical protein 18838..18996 Actinosynnema mirum DSM 43827 8324162 YP_003097839.1 CDS Amir_0019 NC_013093.1 19042 20388 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ade:Adeh_3296 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Ferredoxin--NADP(+) reductase complement(19042..20388) Actinosynnema mirum DSM 43827 8324163 YP_003097840.1 CDS Amir_0020 NC_013093.1 20454 21095 D TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: swi:Swit_3227 anthranilate synthase, component II; glutamine amidotransferase 20454..21095 Actinosynnema mirum DSM 43827 8324164 YP_003097841.1 CDS Amir_0021 NC_013093.1 21196 23241 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: bha:BH2504 serine/threonine protein kinase; serine/threonine protein kinase complement(21196..23241) Actinosynnema mirum DSM 43827 8324165 YP_003097842.1 CDS Amir_0022 NC_013093.1 23322 25025 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: ade:Adeh_3649 serine/threonine protein kinase; serine/threonine protein kinase complement(23322..25025) Actinosynnema mirum DSM 43827 8324166 YP_003097843.1 CDS Amir_0023 NC_013093.1 25025 26491 R PFAM: penicillin-binding protein transpeptidase; KEGG: penicillin-binding protein 2; K05515 penicillin binding protein 2; peptidoglycan glycosyltransferase complement(25025..26491) Actinosynnema mirum DSM 43827 8324167 YP_003097844.1 CDS Amir_0024 NC_013093.1 26488 27951 R PFAM: cell cycle protein; KEGG: bcb:BCB4264_A4012 stage V sporulation protein E; cell cycle protein complement(26488..27951) Actinosynnema mirum DSM 43827 8324168 YP_003097845.1 CDS Amir_0025 NC_013093.1 27955 29379 R PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: tgr:Tgr7_0952 protein phosphatase 2C-like protein; protein serine/threonine phosphatase complement(27955..29379) Actinosynnema mirum DSM 43827 8324169 YP_003097846.1 CDS Amir_0026 NC_013093.1 29376 29840 R PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: mxa:MXAN_4649 FHA domain protein; FHA domain containing protein complement(29376..29840) Actinosynnema mirum DSM 43827 8324170 YP_003097847.1 CDS Amir_0027 NC_013093.1 29891 31153 R PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: eba:ebA2155 hypothetical protein; FHA domain containing protein complement(29891..31153) Actinosynnema mirum DSM 43827 8324171 YP_003097848.1 CDS Amir_0028 NC_013093.1 31797 32417 D hypothetical protein 31797..32417 Actinosynnema mirum DSM 43827 8324173 YP_003097849.1 CDS Amir_0029 NC_013093.1 32468 33103 D PFAM: NAD-dependent epimerase/dehydratase; KEGG: xca:xccb100_0085 hypothetical protein; NAD-dependent epimerase/dehydratase 32468..33103 Actinosynnema mirum DSM 43827 8324174 YP_003097850.1 CDS Amir_0030 NC_013093.1 33316 34593 R KEGG: bur:Bcep18194_B3008 FAD-linked oxidoreductase; TIGRFAM: FAD-linked oxidoreductase; PFAM: D-arabinono-14-lactone oxidase; FAD linked oxidase domain protein; FAD-linked oxidoreductase complement(33316..34593) Actinosynnema mirum DSM 43827 8324175 YP_003097851.1 CDS Amir_0031 NC_013093.1 34677 35864 D PFAM: alanine racemase domain protein; KEGG: bur:Bcep18194_B3007 amino acid aldolase or racemase-like; alanine racemase domain-containing protein 34677..35864 Actinosynnema mirum DSM 43827 8324176 YP_003097852.1 CDS Amir_0032 NC_013093.1 35861 36493 R PFAM: regulatory protein TetR; KEGG: scl:sce5559 HTH-type transcriptional regulator BetI; TetR family transcriptional regulator complement(35861..36493) Actinosynnema mirum DSM 43827 8324177 YP_003097853.1 CDS Amir_0033 NC_013093.1 36613 37875 D TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; KEGG: hch:HCH_06907 beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase; beta-galactosidase 36613..37875 Actinosynnema mirum DSM 43827 8324178 YP_003097854.1 CDS Amir_0034 NC_013093.1 37872 39179 D PFAM: major facilitator superfamily MFS_1; KEGG: ccs:CCNA_02400 transporter, major facilitator superfamily; major facilitator superfamily protein 37872..39179 Actinosynnema mirum DSM 43827 8324179 YP_003097855.1 CDS Amir_0035 NC_013093.1 39176 39943 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: hypothetical protein; short-chain dehydrogenase/reductase SDR 39176..39943 Actinosynnema mirum DSM 43827 8324180 YP_003097856.1 CDS Amir_0036 NC_013093.1 40316 40678 R hypothetical protein complement(40316..40678) Actinosynnema mirum DSM 43827 8324181 YP_003097857.1 CDS Amir_0037 NC_013093.1 41233 42615 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; hypothetical protein; KEGG: hypothetical protein; XRE family transcriptional regulator 41233..42615 Actinosynnema mirum DSM 43827 8324182 YP_003097858.1 CDS Amir_0038 NC_013093.1 42689 43585 D PFAM: aminoglycoside phosphotransferase; KEGG: bcz:BCZK4351 homoserine kinase type II (protein kinase fold); aminoglycoside phosphotransferase 42689..43585 Actinosynnema mirum DSM 43827 8324183 YP_003097859.1 CDS Amir_0039 NC_013093.1 43715 43996 D hypothetical protein 43715..43996 Actinosynnema mirum DSM 43827 8324184 YP_003097860.1 CDS Amir_0040 NC_013093.1 44172 45191 R PFAM: copper resistance D domain protein; KEGG: bja:bll4878 copper export protein; copper resistance D domain-containing protein complement(44172..45191) Actinosynnema mirum DSM 43827 8324185 YP_003097861.1 CDS Amir_0041 NC_013093.1 45188 45736 R PFAM: copper resistance protein CopC; KEGG: bra:BRADO4155 copper resistance protein; copper resistance protein CopC complement(45188..45736) Actinosynnema mirum DSM 43827 8324186 YP_003097862.1 CDS Amir_0042 NC_013093.1 45733 46482 R PFAM: nuclear export factor GLE1; KEGG: sme:SMa1200 hypothetical protein; nuclear export factor GLE1 complement(45733..46482) Actinosynnema mirum DSM 43827 8324187 YP_003097863.1 CDS Amir_0043 NC_013093.1 46508 47065 R KEGG: bxe:Bxe_B0776 membrane glycoprotein; hypothetical protein complement(46508..47065) Actinosynnema mirum DSM 43827 8324188 YP_003097864.1 CDS Amir_0044 NC_013093.1 47159 48991 D TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: ppw:PputW619_2676 choline/carnitine/betaine transporter; choline/carnitine/betaine transporter 47159..48991 Actinosynnema mirum DSM 43827 8324189 YP_003097865.1 CDS Amir_0045 NC_013093.1 49044 49484 R hypothetical protein complement(49044..49484) Actinosynnema mirum DSM 43827 8324190 YP_003097866.1 CDS Amir_0046 NC_013093.1 49586 51220 D nuclease (RecB family)-like protein 49586..51220 Actinosynnema mirum DSM 43827 8324191 YP_003097867.1 CDS Amir_0047 NC_013093.1 51262 52014 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bac:BamMC406_2467 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(51262..52014) Actinosynnema mirum DSM 43827 8324192 YP_003097868.1 CDS Amir_0048 NC_013093.1 52050 52175 R hypothetical protein complement(52050..52175) Actinosynnema mirum DSM 43827 8324193 YP_003097869.1 CDS Amir_0049 NC_013093.1 52353 54134 D PFAM: gamma-glutamyltranspeptidase; KEGG: bbt:BBta_2852 gamma- glutamyltranspeptidase; gamma-glutamyltransferase 52353..54134 Actinosynnema mirum DSM 43827 8324194 YP_003097870.1 CDS Amir_0050 NC_013093.1 54212 54541 R hypothetical protein complement(54212..54541) Actinosynnema mirum DSM 43827 8324195 YP_003097871.1 CDS Amir_0051 NC_013093.1 55503 55877 R hypothetical protein complement(55503..55877) Actinosynnema mirum DSM 43827 8324196 YP_003097872.1 CDS Amir_0052 NC_013093.1 56251 57537 D KEGG: azc:AZC_0951 hypothetical protein; hypothetical protein 56251..57537 Actinosynnema mirum DSM 43827 8324197 YP_003097873.1 CDS Amir_0053 NC_013093.1 57672 59063 D KEGG: FAP262; flagellar associated protein; hypothetical protein 57672..59063 Actinosynnema mirum DSM 43827 8324198 YP_003097874.1 CDS Amir_0054 NC_013093.1 59060 60733 D PFAM: glycosyl transferase family 2; KEGG: rce:RC1_0824 glycosyl transferase family protein; family 2 glycosyl transferase 59060..60733 Actinosynnema mirum DSM 43827 8324199 YP_003097875.1 CDS Amir_0055 NC_013093.1 60861 64376 R PFAM: glycosyl transferase family 2; methyltransferase type 12; methyltransferase type 11; KEGG: ppf:Pput_3926 glycosyl transferase family protein; family 2 glycosyl transferase complement(60861..64376) Actinosynnema mirum DSM 43827 8324200 YP_003097876.1 CDS Amir_0056 NC_013093.1 64376 65581 R KEGG: sus:Acid_4178 ribonuclease; hypothetical protein complement(64376..65581) Actinosynnema mirum DSM 43827 8324201 YP_003097877.1 CDS Amir_0057 NC_013093.1 65703 68078 R PFAM: glycosyl transferase group 1; KEGG: xcb:XC_3634 glycosyltransferase; group 1 glycosyl transferase complement(65703..68078) Actinosynnema mirum DSM 43827 8324202 YP_003097878.1 CDS Amir_0058 NC_013093.1 68337 69401 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: swi:Swit_4011 methyltransferase type 12; type 11 methyltransferase complement(68337..69401) Actinosynnema mirum DSM 43827 8324203 YP_003097879.1 CDS Amir_0059 NC_013093.1 69961 70266 R hypothetical protein complement(69961..70266) Actinosynnema mirum DSM 43827 8324204 YP_003097880.1 CDS Amir_0060 NC_013093.1 70271 70696 R PFAM: OsmC family protein; KEGG: mlo:mlr4254 osmotically inducible protein C, ATP/GTP binding protein; OsmC family protein complement(70271..70696) Actinosynnema mirum DSM 43827 8324205 YP_003097881.1 CDS Amir_0061 NC_013093.1 70942 71337 R hypothetical protein complement(70942..71337) Actinosynnema mirum DSM 43827 8324207 YP_003097882.1 CDS Amir_0062 NC_013093.1 71534 73003 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: afw:Anae109_0839 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 71534..73003 Actinosynnema mirum DSM 43827 8324208 YP_003097883.1 CDS Amir_0063 NC_013093.1 73127 73564 D hypothetical protein 73127..73564 Actinosynnema mirum DSM 43827 8324209 YP_003097884.1 CDS Amir_0064 NC_013093.1 73786 75072 D PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: signal transduction histidine kinase, LytS; K07704 two-component system, LytT family, sensor histidine kinase LytS; signal transduction histidine kinase LytS 73786..75072 Actinosynnema mirum DSM 43827 8324210 YP_003097885.1 CDS Amir_0065 NC_013093.1 75077 75244 R hypothetical protein complement(75077..75244) Actinosynnema mirum DSM 43827 8324211 YP_003097886.1 CDS Amir_0066 NC_013093.1 75285 76157 D PFAM: peptidase S49; KEGG: rce:RC1_1672 proteinase SohB; peptidase S49 75285..76157 Actinosynnema mirum DSM 43827 8324212 YP_003097887.1 CDS Amir_0067 NC_013093.1 76254 77081 D PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; KEGG: gur:Gura_2791 LytTR family two component transcriptional regulator; LytTR family two component transcriptional regulator 76254..77081 Actinosynnema mirum DSM 43827 8324213 YP_003097888.1 CDS Amir_0068 NC_013093.1 77078 77500 D hypothetical protein 77078..77500 Actinosynnema mirum DSM 43827 8324214 YP_003097889.1 CDS Amir_0069 NC_013093.1 77504 79315 D PFAM: Na+/solute symporter; KEGG: dac:Daci_5957 SSS family solute/sodium (Na+) symporter; Na+/solute symporter 77504..79315 Actinosynnema mirum DSM 43827 8324215 YP_003097890.1 CDS Amir_0070 NC_013093.1 79609 79965 D PFAM: protein of unknown function DUF485; KEGG: gme:Gmet_3287 hypothetical protein; hypothetical protein 79609..79965 Actinosynnema mirum DSM 43827 8324216 YP_003097891.1 CDS Amir_0071 NC_013093.1 79962 81548 D TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: bca:BCE_1726 sodium/solute symporter family protein; SSS sodium solute transporter superfamily protein 79962..81548 Actinosynnema mirum DSM 43827 8324217 YP_003097892.1 CDS Amir_0072 NC_013093.1 81691 82116 D TIGRFAM: DNA binding domain protein, excisionase family; KEGG: maq:Maqu_3385 DNA binding domain-containing protein; excisionase family DNA binding domain-containing protein 81691..82116 Actinosynnema mirum DSM 43827 8324218 YP_003097893.1 CDS Amir_0073 NC_013093.1 82184 82774 D KEGG: lpc:LPC_2191 hypothetical protein; hypothetical protein 82184..82774 Actinosynnema mirum DSM 43827 8324219 YP_003097894.1 CDS Amir_0074 NC_013093.1 82815 83162 D PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: rfr:Rfer_3913 rhodanese-like protein; rhodanese domain-containing protein 82815..83162 Actinosynnema mirum DSM 43827 8324220 YP_003097895.1 CDS Amir_0075 NC_013093.1 83164 84072 D KEGG: sfu:Sfum_2194 hypothetical protein; hypothetical protein 83164..84072 Actinosynnema mirum DSM 43827 8324221 YP_003097896.1 CDS Amir_0076 NC_013093.1 84163 85212 D PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: hypothetical protein; glycerophosphoryl diester phosphodiesterase 84163..85212 Actinosynnema mirum DSM 43827 8324222 YP_003097897.1 CDS Amir_0077 NC_013093.1 85244 86476 R PFAM: cytochrome P450; KEGG: jan:Jann_1726 cytochrome P450; cytochrome P450 complement(85244..86476) Actinosynnema mirum DSM 43827 8324223 YP_003097898.1 CDS Amir_0078 NC_013093.1 86596 87294 D PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: gbm:Gbem_3150 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 86596..87294 Actinosynnema mirum DSM 43827 8324224 YP_003097899.1 CDS Amir_0079 NC_013093.1 87313 88257 D PFAM: SEC-C motif domain protein; SEC-C motif domain-containing protein 87313..88257 Actinosynnema mirum DSM 43827 8324225 YP_003097900.1 CDS Amir_0080 NC_013093.1 88330 88656 D PFAM: protein of unknown function DUF952; KEGG: rru:Rru_A0513 hypothetical protein; hypothetical protein 88330..88656 Actinosynnema mirum DSM 43827 8324226 YP_003097901.1 CDS Amir_0081 NC_013093.1 88777 89808 D KEGG: xau:Xaut_1560 phenylacetaldoxime dehydratase; phenylacetaldoxime dehydratase 88777..89808 Actinosynnema mirum DSM 43827 8324227 YP_003097902.1 CDS Amir_0082 NC_013093.1 89920 90483 R PFAM: Ferritin Dps family protein; KEGG: hypothetical protein; Ferritin Dps family protein complement(89920..90483) Actinosynnema mirum DSM 43827 8324228 YP_003097903.1 CDS Amir_0083 NC_013093.1 90632 91879 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(90632..91879) Actinosynnema mirum DSM 43827 8324229 YP_003097904.1 CDS Amir_0084 NC_013093.1 92019 92672 R KEGG: bha:BH0832 hypothetical protein; hypothetical protein complement(92019..92672) Actinosynnema mirum DSM 43827 8324230 YP_003097905.1 CDS Amir_0085 NC_013093.1 92746 93540 R PFAM: abortive infection protein; KEGG: dal:Dalk_0566 abortive infection protein; abortive infection protein complement(92746..93540) Actinosynnema mirum DSM 43827 8324231 YP_003097906.1 CDS Amir_0086 NC_013093.1 93550 94308 R KEGG: scl:sce4194 hypothetical protein; hypothetical protein complement(93550..94308) Actinosynnema mirum DSM 43827 8324232 YP_003097907.1 CDS Amir_0087 NC_013093.1 94407 95036 D hypothetical protein 94407..95036 Actinosynnema mirum DSM 43827 8324233 YP_003097908.1 CDS Amir_0088 NC_013093.1 95197 96399 R PFAM: homogentisate 12-dioxygenase; KEGG: bcz:BCZK0217 homogentisate 1,2-dioxygenase; homogentisate 12-dioxygenase complement(95197..96399) Actinosynnema mirum DSM 43827 8324234 YP_003097909.1 CDS Amir_0089 NC_013093.1 96535 97335 D KEGG: sus:Acid_6517 hypothetical protein; hypothetical protein 96535..97335 Actinosynnema mirum DSM 43827 8324235 YP_003097910.1 CDS Amir_0090 NC_013093.1 97332 98516 D PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969; KEGG: jan:Jann_1436 fumarylacetoacetate hydrolase; fumarylacetoacetase 97332..98516 Actinosynnema mirum DSM 43827 8324236 YP_003097911.1 CDS Amir_0091 NC_013093.1 98519 99178 D PFAM: regulatory protein IclR; SMART: regulatory protein IclR; KEGG: dac:Daci_0951 IclR family transcriptional regulator; IclR family transcriptional regulator 98519..99178 Actinosynnema mirum DSM 43827 8324237 YP_003097912.1 CDS Amir_0092 NC_013093.1 99260 100771 D PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: bsu:BSU38760 cytochrome bd ubiquinol oxidase (subunit I); cytochrome bd ubiquinol oxidase subunit I 99260..100771 Actinosynnema mirum DSM 43827 8324238 YP_003097913.1 CDS Amir_0093 NC_013093.1 100786 101790 D KEGG: glo:Glov_1209 cytochrome D ubiquinol oxidase, subunit II; TIGRFAM: cytochrome D ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; cytochrome D ubiquinol oxidase, subunit II 100786..101790 Actinosynnema mirum DSM 43827 8324239 YP_003097914.1 CDS Amir_0094 NC_013093.1 102023 103051 R SMART: TIR protein; KEGG: vvy:VV1926 hypothetical protein; TIR protein complement(102023..103051) Actinosynnema mirum DSM 43827 8324240 YP_003097915.1 CDS Amir_0095 NC_013093.1 103158 106223 D KEGG: bpt:Bpet3362 HlyB/MsbA family ABC transporter; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; cysteine ABC transporter permease/ATP-binding protein 103158..106223 Actinosynnema mirum DSM 43827 8324241 YP_003097916.1 CDS Amir_0096 NC_013093.1 106220 107338 D PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; GAF domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: pna:Pnap_3765 multi-sensor signal transduction histidine kinase; GAF sensor signal transduction histidine kinase 106220..107338 Actinosynnema mirum DSM 43827 8324242 YP_003097917.1 CDS Amir_0097 NC_013093.1 107555 108184 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: xca:xccb100_3213 two-component system regulatory protein; LuxR family transcriptional regulator complement(107555..108184) Actinosynnema mirum DSM 43827 8324243 YP_003097918.1 CDS Amir_0098 NC_013093.1 108245 108727 D PFAM: GCN5-related N-acetyltransferase; KEGG: bca:BCE_4174 acetyltransferase; GCN5-like N-acetyltransferase 108245..108727 Actinosynnema mirum DSM 43827 8324244 YP_003097919.1 CDS Amir_0099 NC_013093.1 108789 109388 R PFAM: Appr-1-p processing domain protein; KEGG: dal:Dalk_0690 Appr-1-p processing domain protein; Appr-1-p processing domain-containing protein complement(108789..109388) Actinosynnema mirum DSM 43827 8324245 YP_003097920.1 CDS Amir_0100 NC_013093.1 109492 110394 D PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ank:AnaeK_2061 prephenate dehydratase; Prephenate dehydratase 109492..110394 Actinosynnema mirum DSM 43827 8324246 YP_003097921.1 CDS Amir_0101 NC_013093.1 110391 111002 D PFAM: phosphoglycerate mutase; KEGG: lch:Lcho_3955 phosphoglycerate mutase; phosphoglycerate mutase 110391..111002 Actinosynnema mirum DSM 43827 8324247 YP_003097922.1 CDS Amir_0104 NC_013093.1 111845 112261 R hypothetical protein complement(111845..112261) Actinosynnema mirum DSM 43827 8324250 YP_003097923.1 CDS Amir_0105 NC_013093.1 112255 112677 R hypothetical protein complement(112255..112677) Actinosynnema mirum DSM 43827 8324251 YP_003097924.1 CDS Amir_0106 NC_013093.1 112751 112936 R hypothetical protein complement(112751..112936) Actinosynnema mirum DSM 43827 8324252 YP_003097925.1 CDS Amir_0107 NC_013093.1 113121 114014 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 113121..114014 Actinosynnema mirum DSM 43827 8324253 YP_003097926.1 CDS Amir_0108 NC_013093.1 114011 114196 D PFAM: protein of unknown function DUF397; hypothetical protein 114011..114196 Actinosynnema mirum DSM 43827 8324254 YP_003097927.1 CDS Amir_0109 NC_013093.1 114247 114795 R PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ade:Adeh_1652 peptidylprolyl isomerase; peptidylprolyl isomerase complement(114247..114795) Actinosynnema mirum DSM 43827 8324255 YP_003097928.1 CDS Amir_0110 NC_013093.1 115026 118412 D PFAM: glycoside hydrolase family 31; carbohydrate binding family 6; Ricin B lectin; SMART: cellulose binding type IV; Ricin B lectin; KEGG: aba:Acid345_1956 glycoside hydrolase, family 31; glycoside hydrolase family protein 115026..118412 Actinosynnema mirum DSM 43827 8324256 YP_003097929.1 CDS Amir_0112 NC_013093.1 120442 120792 R PFAM: protein of unknown function DUF1025; KEGG: eli:ELI_09390 hypothetical protein; hypothetical protein complement(120442..120792) Actinosynnema mirum DSM 43827 8324258 YP_003097930.1 CDS Amir_0113 NC_013093.1 120797 121825 R KEGG: YALI0F05786p; hypothetical protein complement(120797..121825) Actinosynnema mirum DSM 43827 8324259 YP_003097931.1 CDS Amir_0114 NC_013093.1 121985 122737 D KEGG: hypothetical protein; hypothetical protein 121985..122737 Actinosynnema mirum DSM 43827 8324260 YP_003097932.1 CDS Amir_0115 NC_013093.1 122738 123901 D PFAM: glutathionylspermidine synthase; KEGG: sus:Acid_7141 glutathionylspermidine synthase; glutathionylspermidine synthase 122738..123901 Actinosynnema mirum DSM 43827 8324261 YP_003097933.1 CDS Amir_0116 NC_013093.1 123918 124370 D PFAM: protein of unknown function DUF350; KEGG: met:M446_5403 hypothetical protein; hypothetical protein 123918..124370 Actinosynnema mirum DSM 43827 8324262 YP_003097934.1 CDS Amir_0117 NC_013093.1 124531 125205 R hypothetical protein complement(124531..125205) Actinosynnema mirum DSM 43827 8324263 YP_003097935.1 CDS Amir_0118 NC_013093.1 125363 126613 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 125363..126613 Actinosynnema mirum DSM 43827 8324264 YP_003097936.1 CDS Amir_0119 NC_013093.1 127550 128737 R PFAM: FAD dependent oxidoreductase; HI0933 family protein; KEGG: sus:Acid_5855 FAD dependent oxidoreductase; FAD dependent oxidoreductase complement(127550..128737) Actinosynnema mirum DSM 43827 8324265 YP_003097937.1 CDS Amir_0120 NC_013093.1 128739 129671 R PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4411 luciferase-like; luciferase-like monooxygenase complement(128739..129671) Actinosynnema mirum DSM 43827 8324266 YP_003097938.1 CDS Amir_0121 NC_013093.1 129678 130499 D TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: mno:Mnod_7133 Cof-like hydrolase; Cof-like hydrolase 129678..130499 Actinosynnema mirum DSM 43827 8324267 YP_003097939.1 CDS Amir_0122 NC_013093.1 130616 132532 D KEGG: sml:Smlt0624 transmembrane protein; hypothetical protein 130616..132532 Actinosynnema mirum DSM 43827 8324268 YP_003097940.1 CDS Amir_0123 NC_013093.1 132542 133594 D PFAM: glycosyl transferase family 2; KEGG: rme:Rmet_6128 glycosyl transferase, family 2; ribonuclease III 132542..133594 Actinosynnema mirum DSM 43827 8324269 YP_003097941.1 CDS Amir_0124 NC_013093.1 133597 134106 D PFAM: GtrA family protein; KEGG: GtrA family protein; GtrA family protein 133597..134106 Actinosynnema mirum DSM 43827 8324270 YP_003097942.1 CDS Amir_0125 NC_013093.1 134133 135434 D PFAM: acyltransferase 3; KEGG: acr:Acry_1134 acyltransferase 3; acyltransferase 3 134133..135434 Actinosynnema mirum DSM 43827 8324271 YP_003097943.1 CDS Amir_0126 NC_013093.1 135536 137167 D PFAM: glycosyl transferase group 1; KEGG: pae:PA1391 glycosyl transferase; group 1 glycosyl transferase 135536..137167 Actinosynnema mirum DSM 43827 8324272 YP_003097944.1 CDS Amir_0127 NC_013093.1 137164 138063 D PFAM: glycosyl transferase family 2; KEGG: bcj:BCAL3234 glycosyltransferase; family 2 glycosyl transferase 137164..138063 Actinosynnema mirum DSM 43827 8324273 YP_003097945.1 CDS Amir_0128 NC_013093.1 138200 139384 D KEGG: gox:GOX1488 UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase-like; UDP-galactopyranose mutase 138200..139384 Actinosynnema mirum DSM 43827 8324274 YP_003097946.1 CDS Amir_0129 NC_013093.1 139453 140256 R KEGG: pna:Pnap_3593 hypothetical protein; hypothetical protein complement(139453..140256) Actinosynnema mirum DSM 43827 8324275 YP_003097947.1 CDS Amir_0130 NC_013093.1 140289 141086 R KEGG: dac:Daci_5514 hypothetical protein; hypothetical protein complement(140289..141086) Actinosynnema mirum DSM 43827 8324276 YP_003097948.1 CDS Amir_0131 NC_013093.1 141148 141948 R KEGG: jan:Jann_1080 metallophosphoesterase; hypothetical protein complement(141148..141948) Actinosynnema mirum DSM 43827 8324277 YP_003097949.1 CDS Amir_0132 NC_013093.1 142456 143352 R PFAM: glycosyl transferase family 2; KEGG: apl:APL_1469 glycosyl transferase family protein; family 2 glycosyl transferase complement(142456..143352) Actinosynnema mirum DSM 43827 8324278 YP_003097950.1 CDS Amir_0133 NC_013093.1 143356 144171 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cbc:CbuK_1550 polysaccharide export ATP- binding protein; ABC transporter complement(143356..144171) Actinosynnema mirum DSM 43827 8324279 YP_003097951.1 CDS Amir_0134 NC_013093.1 144188 145099 R PFAM: ABC transporter; KEGG: tbd:Tbd_1878 ABC transporter permease protein; ABC transporter complement(144188..145099) Actinosynnema mirum DSM 43827 8324280 YP_003097952.1 CDS Amir_0135 NC_013093.1 145369 145917 R hypothetical protein complement(145369..145917) Actinosynnema mirum DSM 43827 8324281 YP_003097953.1 CDS Amir_0136 NC_013093.1 146032 147231 D TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V; KEGG: mlo:mlr0102 aminotransferase; cysteine desulfurase family protein 146032..147231 Actinosynnema mirum DSM 43827 8324282 YP_003097954.1 CDS Amir_0137 NC_013093.1 147357 148010 D KEGG: mes:Meso_0486 hypothetical protein; hypothetical protein 147357..148010 Actinosynnema mirum DSM 43827 8324283 YP_003097955.1 CDS Amir_0138 NC_013093.1 148245 149723 R KEGG: scl:sce7164 hypothetical protein; hypothetical protein complement(148245..149723) Actinosynnema mirum DSM 43827 8324284 YP_003097956.1 CDS Amir_0139 NC_013093.1 149847 150821 R TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: hypothetical protein; NAD(P)H quinone oxidoreductase complement(149847..150821) Actinosynnema mirum DSM 43827 8324285 YP_003097957.1 CDS Amir_0140 NC_013093.1 150866 151498 D PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_C_5049 hypothetical protein; GCN5-like N-acetyltransferase 150866..151498 Actinosynnema mirum DSM 43827 8324286 YP_003097958.1 CDS Amir_0141 NC_013093.1 151575 153095 D PFAM: peptidase M28; protease-associated PA domain protein; KEGG: pag:PLES_21241 aminopeptidase; Aminopeptidase Y 151575..153095 Actinosynnema mirum DSM 43827 8324287 YP_003097959.1 CDS Amir_0142 NC_013093.1 153173 154078 R PFAM: protein of unknown function zinc metallopeptidase KEGG: rfr:Rfer_2725 protein of unknown function, zinc metallopeptidase; hypothetical protein complement(153173..154078) Actinosynnema mirum DSM 43827 8324288 YP_003097960.1 CDS Amir_0143 NC_013093.1 154537 156264 R PFAM: 5'-nucleotidase; metallophosphoesterase; KEGG: scl:sce7039 5'-nucleotidase family protein; 5'-nucleotidase complement(154537..156264) Actinosynnema mirum DSM 43827 8324289 YP_003097961.1 CDS Amir_0144 NC_013093.1 156424 156891 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: acp:A2cp1_4259 transcriptional regulator, MarR family; MarR family transcriptional regulator 156424..156891 Actinosynnema mirum DSM 43827 8324290 YP_003097962.1 CDS Amir_0145 NC_013093.1 157221 157970 D PFAM: protein of unknown function DUF81; KEGG: sfu:Sfum_1521 protein of unknown function DUF81; hypothetical protein 157221..157970 Actinosynnema mirum DSM 43827 8324292 YP_003097963.1 CDS Amir_0146 NC_013093.1 158047 159114 R TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: scl:sce8915 histidinol-phosphate transaminase; histidinol-phosphate aminotransferase complement(158047..159114) Actinosynnema mirum DSM 43827 8324293 YP_003097964.1 CDS Amir_0147 NC_013093.1 159236 159919 D PFAM: dienelactone hydrolase; KEGG: cvi:CV_3204 carboxymethylenebutenolidase; dienelactone hydrolase 159236..159919 Actinosynnema mirum DSM 43827 8324294 YP_003097965.1 CDS Amir_0148 NC_013093.1 159963 160340 R KEGG: GK21229 gene product from transcript GK21229- RA; hypothetical protein complement(159963..160340) Actinosynnema mirum DSM 43827 8324295 YP_003097966.1 CDS Amir_0149 NC_013093.1 160367 161743 D KEGG: GH10507 gene product from transcript GH10507- RA; hypothetical protein 160367..161743 Actinosynnema mirum DSM 43827 8324296 YP_003097967.1 CDS Amir_0150 NC_013093.1 161743 163089 D KEGG: reu:Reut_B5390 glycin-rich signal peptide protein; hypothetical protein 161743..163089 Actinosynnema mirum DSM 43827 8324297 YP_003097968.1 CDS Amir_0151 NC_013093.1 163086 163844 D hypothetical protein 163086..163844 Actinosynnema mirum DSM 43827 8324298 YP_003097969.1 CDS Amir_0152 NC_013093.1 163955 165910 D TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: sil:SPO1959 acetoacetyl-CoA synthetase; acetoacetyl-CoA synthase 163955..165910 Actinosynnema mirum DSM 43827 8324299 YP_003097970.1 CDS Amir_0153 NC_013093.1 166576 168750 R KEGG: SAMD1; sterile alpha motif domain containing 1; hypothetical protein complement(166576..168750) Actinosynnema mirum DSM 43827 8324302 YP_003097971.1 CDS Amir_0154 NC_013093.1 168872 169687 R PFAM: beta-lactamase; KEGG: sml:Smlt3132 beta-lactamase; beta-lactamase complement(168872..169687) Actinosynnema mirum DSM 43827 8324303 YP_003097972.1 CDS Amir_0155 NC_013093.1 169787 171295 D TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: bur:Bcep18194_A5663 DNA translocase FtsK; LPXTG-motif cell wall anchor domain-containing protein 169787..171295 Actinosynnema mirum DSM 43827 8324304 YP_003097973.1 CDS Amir_0156 NC_013093.1 171267 172106 R PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: hha:Hhal_0769 UDP-glucose 4-epimerase; NAD-dependent epimerase/dehydratase complement(171267..172106) Actinosynnema mirum DSM 43827 8324305 YP_003097974.1 CDS Amir_0157 NC_013093.1 172215 172442 D hypothetical protein 172215..172442 Actinosynnema mirum DSM 43827 8324306 YP_003097975.1 CDS Amir_0158 NC_013093.1 172593 174020 D hypothetical protein 172593..174020 Actinosynnema mirum DSM 43827 8324307 YP_003097976.1 CDS Amir_0159 NC_013093.1 174010 174810 R KEGG: scl:sce4085 hypothetical protein; hypothetical protein complement(174010..174810) Actinosynnema mirum DSM 43827 8324308 YP_003097977.1 CDS Amir_0160 NC_013093.1 174893 176107 D PFAM: C-5 cytosine-specific DNA methylase; KEGG: nmc:NMC1992 modification methylase (cytosine- specific DNA methylase); DNA (cytosine-5-)-methyltransferase 174893..176107 Actinosynnema mirum DSM 43827 8324309 YP_003097978.1 CDS Amir_0161 NC_013093.1 176495 177745 D TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: ADR019Cp; K01066 esterase / lipase; LPXTG-motif cell wall anchor domain-containing protein 176495..177745 Actinosynnema mirum DSM 43827 8324310 YP_003097979.1 CDS Amir_0162 NC_013093.1 177884 178057 D hypothetical protein 177884..178057 Actinosynnema mirum DSM 43827 8324311 YP_003097980.1 CDS Amir_0163 NC_013093.1 178054 178677 D PFAM: protein of unknown function DUF1089; KEGG: sme:SMc03980 hypothetical protein; hypothetical protein 178054..178677 Actinosynnema mirum DSM 43827 8324312 YP_003097981.1 CDS Amir_0164 NC_013093.1 178764 179948 R TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: gbm:Gbem_1434 acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase complement(178764..179948) Actinosynnema mirum DSM 43827 8324313 YP_003097982.1 CDS Amir_0165 NC_013093.1 179961 181772 R KEGG: CG32656; hypothetical protein complement(179961..181772) Actinosynnema mirum DSM 43827 8324314 YP_003097983.1 CDS Amir_0166 NC_013093.1 181830 182186 R hypothetical protein complement(181830..182186) Actinosynnema mirum DSM 43827 8324315 YP_003097984.1 CDS Amir_0167 NC_013093.1 182183 183073 R KEGG: ade:Adeh_1681 PE-PGRS family protein; PE-PGRS family protein complement(182183..183073) Actinosynnema mirum DSM 43827 8324316 YP_003097985.1 CDS Amir_0168 NC_013093.1 183317 184273 R catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase complement(183317..184273) Actinosynnema mirum DSM 43827 8324317 YP_003097986.1 CDS Amir_0169 NC_013093.1 184371 185606 R KEGG: sal:Sala_2314 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein; amidohydrolase complement(184371..185606) Actinosynnema mirum DSM 43827 8324318 YP_003097987.1 CDS Amir_0170 NC_013093.1 185647 186177 D hypothetical protein 185647..186177 Actinosynnema mirum DSM 43827 8324319 YP_003097988.1 CDS Amir_0171 NC_013093.1 186174 186656 D PFAM: CMP/dCMP deaminase zinc-binding; KEGG: gur:Gura_0055 CMP/dCMP deaminase, zinc- binding; zinc-binding CMP/dCMP deaminase 186174..186656 Actinosynnema mirum DSM 43827 8324320 YP_003097989.1 CDS Amir_0172 NC_013093.1 186876 188189 R PFAM: integrase family protein; KEGG: sus:Acid_5994 phage integrase family protein; integrase family protein complement(186876..188189) Actinosynnema mirum DSM 43827 8324322 YP_003097990.1 CDS Amir_0173 NC_013093.1 188197 188499 R TIGRFAM: DNA binding domain protein, excisionase family; excisionase family DNA binding domain-containing protein complement(188197..188499) Actinosynnema mirum DSM 43827 8324323 YP_003097991.1 CDS Amir_0174 NC_013093.1 188496 189647 R KEGG: rso:RSc2483 hypothetical protein; hypothetical protein complement(188496..189647) Actinosynnema mirum DSM 43827 8324324 YP_003097992.1 CDS Amir_0175 NC_013093.1 189644 190216 R hypothetical protein complement(189644..190216) Actinosynnema mirum DSM 43827 8324325 YP_003097993.1 CDS Amir_0176 NC_013093.1 190299 190574 R hypothetical protein complement(190299..190574) Actinosynnema mirum DSM 43827 8324326 YP_003097994.1 CDS Amir_0177 NC_013093.1 190727 192922 R PFAM: cell divisionFtsK/SpoIIIE; KEGG: bac:BamMC406_0006 cell divisionFtsK/SpoIIIE; cell division protein FtsK/SpoIIIE complement(190727..192922) Actinosynnema mirum DSM 43827 8324327 YP_003097995.1 CDS Amir_0178 NC_013093.1 192919 193884 R KEGG: bmv:BMASAVP1_A1237 hypothetical protein; hypothetical protein complement(192919..193884) Actinosynnema mirum DSM 43827 8324328 YP_003097996.1 CDS Amir_0179 NC_013093.1 193881 193976 R hypothetical protein complement(193881..193976) Actinosynnema mirum DSM 43827 8324329 YP_003097997.1 CDS Amir_0180 NC_013093.1 194069 194224 R hypothetical protein complement(194069..194224) Actinosynnema mirum DSM 43827 8324330 YP_003097998.1 CDS Amir_0181 NC_013093.1 194253 194564 R hypothetical protein complement(194253..194564) Actinosynnema mirum DSM 43827 8324331 YP_003097999.1 CDS Amir_0182 NC_013093.1 194728 195081 D SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 194728..195081 Actinosynnema mirum DSM 43827 8324332 YP_003098000.1 CDS Amir_0183 NC_013093.1 195181 196023 R PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein complement(195181..196023) Actinosynnema mirum DSM 43827 8324333 YP_003098001.1 CDS Amir_0184 NC_013093.1 196208 196987 D PFAM: aminotransferase class IV; KEGG: smt:Smal_1152 hypothetical protein; hypothetical protein 196208..196987 Actinosynnema mirum DSM 43827 8324334 YP_003098002.1 CDS Amir_0185 NC_013093.1 197023 197958 D PFAM: protein of unknown function DUF323; SMART: helix-turn-helix domain protein; KEGG: scl:sce5487 protein kinase; XRE family transcriptional regulator 197023..197958 Actinosynnema mirum DSM 43827 8324335 YP_003098003.1 CDS Amir_0186 NC_013093.1 198068 198250 R hypothetical protein complement(198068..198250) Actinosynnema mirum DSM 43827 8324336 YP_003098004.1 CDS Amir_0187 NC_013093.1 198251 198898 R KEGG: rsq:Rsph17025_0912 hypothetical protein; hypothetical protein complement(198251..198898) Actinosynnema mirum DSM 43827 8324337 YP_003098005.1 CDS Amir_0188 NC_013093.1 198895 199368 R KEGG: bxe:Bxe_C1257 hypothetical protein; hypothetical protein complement(198895..199368) Actinosynnema mirum DSM 43827 8324338 YP_003098006.1 CDS Amir_0189 NC_013093.1 199368 200309 R PFAM: peptidase C14 caspase catalytic subunit p20; KEGG: bcr:BCAH187_E0055 peptidase C14 caspase catalytic subunit P20; peptidase C14 caspase catalytic subunit p20 complement(199368..200309) Actinosynnema mirum DSM 43827 8324339 YP_003098007.1 CDS Amir_0190 NC_013093.1 200314 200691 R PFAM: Domain of unknown function DUF1863; KEGG: sbm:Shew185_4383 hypothetical protein; hypothetical protein complement(200314..200691) Actinosynnema mirum DSM 43827 8324340 YP_003098008.1 CDS Amir_0191 NC_013093.1 201557 202771 R PFAM: protein-L-isoaspartate(D-aspartate) O- methyltransferase; methyltransferase type 11; KEGG: bmj:BMULJ_02352 protein-L-isoaspartate (D- aspartate) O-methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase complement(201557..202771) Actinosynnema mirum DSM 43827 8324341 YP_003098009.1 CDS Amir_0192 NC_013093.1 202768 203733 R KEGG: scl:sce7176 hypothetical protein; hypothetical protein complement(202768..203733) Actinosynnema mirum DSM 43827 8324342 YP_003098010.1 CDS Amir_0193 NC_013093.1 203733 204038 R hypothetical protein complement(203733..204038) Actinosynnema mirum DSM 43827 8324343 YP_003098011.1 CDS Amir_0194 NC_013093.1 204230 205435 D PFAM: helix-turn-helix domain protein; hypothetical protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3401 phage regulatory protein; XRE family transcriptional regulator 204230..205435 Actinosynnema mirum DSM 43827 8324344 YP_003098012.1 CDS Amir_0195 NC_013093.1 206393 208858 D PFAM: endonuclease/exonuclease/phosphatase; KEGG: scl:sce0688 endonuclease/exonuclease/phosphatase family protein; endonuclease/exonuclease/phosphatase 206393..208858 Actinosynnema mirum DSM 43827 8324345 YP_003098013.1 CDS Amir_0196 NC_013093.1 208921 209328 R PFAM: endoribonuclease L-PSP; KEGG: scl:sce5646 hypothetical protein; endoribonuclease L-PSP complement(208921..209328) Actinosynnema mirum DSM 43827 8324346 YP_003098014.1 CDS Amir_0197 NC_013093.1 209402 210040 D KEGG: mlo:mlr3102 transcriptional regulator; TetR family transcriptional regulator 209402..210040 Actinosynnema mirum DSM 43827 8324347 YP_003098015.1 CDS Amir_0198 NC_013093.1 210404 212551 R PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pca:Pcar_1336 methyl-accepting chemotaxis protein (MCP); methyl-accepting chemotaxis sensory transducer complement(210404..212551) Actinosynnema mirum DSM 43827 8324349 YP_003098016.1 CDS Amir_0199 NC_013093.1 212696 214294 R PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(212696..214294) Actinosynnema mirum DSM 43827 8324350 YP_003098017.1 CDS Amir_0200 NC_013093.1 214464 215432 D PFAM: periplasmic binding protein; KEGG: atc:AGR_pAT_447 DtxR/iron regulated lipoprotein precursor; periplasmic binding protein 214464..215432 Actinosynnema mirum DSM 43827 8324351 YP_003098018.1 CDS Amir_0201 NC_013093.1 215613 217754 D KEGG: gbm:Gbem_0212 DNA polymerase III subunits gamma/tau; TIGRFAM: DNA polymerase III subunits gamma/tau; PFAM: ATPase AAA; SMART: ATPase AAA; DNA polymerase III subunits gamma/tau 215613..217754 Actinosynnema mirum DSM 43827 8324353 YP_003098019.1 CDS Amir_0202 NC_013093.1 217802 218149 D PFAM: conserved hypothetical protein; KEGG: gme:Gmet_3421 hypothetical protein; hypothetical protein 217802..218149 Actinosynnema mirum DSM 43827 8324354 YP_003098020.1 CDS recR NC_013093.1 218149 218742 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 218149..218742 Actinosynnema mirum DSM 43827 8324355 YP_003098021.1 CDS Amir_0204 NC_013093.1 218756 219226 D KEGG: bcz:BCZK2509 hypothetical protein; hypothetical protein 218756..219226 Actinosynnema mirum DSM 43827 8324356 YP_003098022.1 CDS Amir_0205 NC_013093.1 225081 228347 R PFAM: transcriptional activator domain; TPR repeat- containing protein; hypothetical protein; NB-ARC domain protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator complement(225081..228347) Actinosynnema mirum DSM 43827 8324361 YP_003098023.1 CDS Amir_0206 NC_013093.1 228577 230262 D PFAM: extracellular solute-binding protein family 5; KEGG: hap:HAPS_0936 periplasmic dipeptide transport protein DppA; family 5 extracellular solute-binding protein 228577..230262 Actinosynnema mirum DSM 43827 8324362 YP_003098024.1 CDS Amir_0207 NC_013093.1 230308 231318 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pde:Pden_1670 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane proteint 230308..231318 Actinosynnema mirum DSM 43827 8324363 YP_003098025.1 CDS Amir_0208 NC_013093.1 231325 232257 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH3642 dipeptide ABC transporter (permease); dipeptide ABC transporter permease 231325..232257 Actinosynnema mirum DSM 43827 8324364 YP_003098026.1 CDS Amir_0209 NC_013093.1 232263 233258 D KEGG: bja:bll2870 ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 232263..233258 Actinosynnema mirum DSM 43827 8324365 YP_003098027.1 CDS Amir_0210 NC_013093.1 233255 234397 D KEGG: bja:blr1357 peptide ABC transporter ATP- binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 233255..234397 Actinosynnema mirum DSM 43827 8324366 YP_003098028.1 CDS Amir_0211 NC_013093.1 234560 236698 D PFAM: N-6 DNA methylase; KEGG: xom:XOO_3262 type I restriction system adenine methylase; N-6 DNA methylase 234560..236698 Actinosynnema mirum DSM 43827 8324367 YP_003098029.1 CDS Amir_0212 NC_013093.1 237187 237762 D KEGG: pol:Bpro_3150 DedA; membrane-associated protein 237187..237762 Actinosynnema mirum DSM 43827 8324368 YP_003098030.1 CDS Amir_0213 NC_013093.1 237857 239653 R KEGG: csa:Csal_2535 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; 2-isopropylmalate synthase complement(237857..239653) Actinosynnema mirum DSM 43827 8324369 YP_003098031.1 CDS Amir_0214 NC_013093.1 239881 240186 D hypothetical protein 239881..240186 Actinosynnema mirum DSM 43827 8324370 YP_003098032.1 CDS Amir_0215 NC_013093.1 240214 240846 R PFAM: nitroreductase; KEGG: ank:AnaeK_1659 nitroreductase; nitroreductase complement(240214..240846) Actinosynnema mirum DSM 43827 8324371 YP_003098033.1 CDS Amir_0216 NC_013093.1 240873 242096 R KEGG: mxa:MXAN_5370 lipoprotein; hypothetical protein complement(240873..242096) Actinosynnema mirum DSM 43827 8324372 YP_003098034.1 CDS Amir_0217 NC_013093.1 242173 243438 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 242173..243438 Actinosynnema mirum DSM 43827 8324373 YP_003098035.1 CDS Amir_0218 NC_013093.1 243435 244502 D KEGG: bcb:BCB4264_A3899 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase dimerization region; Semialdehyde dehydrogenase NAD - binding; aspartate-semialdehyde dehydrogenase 243435..244502 Actinosynnema mirum DSM 43827 8324374 YP_003098036.1 CDS Amir_0219 NC_013093.1 244506 245936 D PFAM: carbohydrate kinase FGGY; KEGG: bcb:BCB4264_A2253 gluconate kinase; carbohydrate kinase FGGY 244506..245936 Actinosynnema mirum DSM 43827 8324375 YP_003098037.1 CDS Amir_0220 NC_013093.1 246130 246333 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: vsa:VSAL_II0614 cold shock-like protein; cold-shock DNA-binding domain-containing protein 246130..246333 Actinosynnema mirum DSM 43827 8324376 YP_003098038.1 CDS Amir_0221 NC_013093.1 246436 247614 R PFAM: major facilitator superfamily MFS_1; KEGG: ppg:PputGB1_3286 major facilitator transporter; major facilitator superfamily protein complement(246436..247614) Actinosynnema mirum DSM 43827 8324377 YP_003098039.1 CDS Amir_0222 NC_013093.1 247767 249221 D PFAM: Catalase domain protein; KEGG: eta:ETA_17240 catalase; Catalase 247767..249221 Actinosynnema mirum DSM 43827 8324378 YP_003098040.1 CDS Amir_0223 NC_013093.1 249410 249832 D PFAM: OsmC family protein; KEGG: bpy:Bphyt_6798 OsmC family protein; OsmC family protein 249410..249832 Actinosynnema mirum DSM 43827 8324379 YP_003098041.1 CDS Amir_0224 NC_013093.1 249865 250341 D PFAM: Ferritin Dps family protein; KEGG: mpo:Mpop_0322 ferritin Dps family protein; Ferritin Dps family protein 249865..250341 Actinosynnema mirum DSM 43827 8324380 YP_003098042.1 CDS Amir_0225 NC_013093.1 250415 250981 R PFAM: NADPH-dependent FMN reductase; KEGG: bpl:BURPS1106A_A1934 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase complement(250415..250981) Actinosynnema mirum DSM 43827 8324381 YP_003098043.1 CDS Amir_0226 NC_013093.1 251061 252113 D PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: rce:RC1_2418 lipase; alpha/beta hydrolase fold-3 domain-containing protein 251061..252113 Actinosynnema mirum DSM 43827 8324382 YP_003098044.1 CDS Amir_0227 NC_013093.1 252213 254027 R PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S15; KEGG: pzu:PHZ_c2763 dipeptidyl aminopeptidase/acylaminoacyl-peptidase; peptidase S9 prolyl oligopeptidase active site domain-containing protein complement(252213..254027) Actinosynnema mirum DSM 43827 8324383 YP_003098045.1 CDS Amir_0228 NC_013093.1 254024 254854 R PFAM: methyltransferase type 11; Cyclopropane-fatty- acyl-phospholipid synthase; methyltransferase type 12; KEGG: hha:Hhal_0984 methyltransferase type 11; type 11 methyltransferase complement(254024..254854) Actinosynnema mirum DSM 43827 8324384 YP_003098046.1 CDS Amir_0229 NC_013093.1 255115 255591 R SYNPO2L; KEGG: SYNPO2L; synaptopodin 2-like; synaptopodin 2-like protein complement(255115..255591) Actinosynnema mirum DSM 43827 8324385 YP_003098047.1 CDS Amir_0232 NC_013093.1 256654 257529 R hypothetical protein complement(256654..257529) Actinosynnema mirum DSM 43827 8324388 YP_003098048.1 CDS Amir_0233 NC_013093.1 258162 259121 R PFAM: metallophosphoesterase; KEGG: hch:HCH_04892 phosphohydrolase; metallophosphoesterase complement(258162..259121) Actinosynnema mirum DSM 43827 8324390 YP_003098049.1 CDS Amir_0234 NC_013093.1 259185 259652 D KEGG: mxa:MXAN_5202 GatB/YqeY domain protein; GatB/YqeY domain-containing protein 259185..259652 Actinosynnema mirum DSM 43827 8324391 YP_003098050.1 CDS Amir_0235 NC_013093.1 259758 262250 R PFAM: glycosyl transferase family 51; PASTA domain containing protein; penicillin-binding protein transpeptidase; SMART: PASTA domain containing protein; KEGG: azc:AZC_0337 penicillin-binding protein 1A; glycosyl transferase family protein complement(259758..262250) Actinosynnema mirum DSM 43827 8324392 YP_003098051.1 CDS Amir_0236 NC_013093.1 262504 262797 D PFAM: transcription factor WhiB; transcription factor WhiB 262504..262797 Actinosynnema mirum DSM 43827 8324393 YP_003098052.1 CDS Amir_0237 NC_013093.1 262823 263947 R PFAM: anion-transporting ATPase; KEGG: acp:A2cp1_0984 adventurous gliding motility protein R; anion-transporting ATPase complement(262823..263947) Actinosynnema mirum DSM 43827 8324394 YP_003098053.1 CDS Amir_0238 NC_013093.1 263944 264936 R PFAM: anion-transporting ATPase; KEGG: afw:Anae109_0972 chromosome partitioning-like ATPase; anion-transporting ATPase complement(263944..264936) Actinosynnema mirum DSM 43827 8324395 YP_003098054.1 CDS Amir_0239 NC_013093.1 265300 265569 R hypothetical protein complement(265300..265569) Actinosynnema mirum DSM 43827 8324396 YP_003098055.1 CDS Amir_0240 NC_013093.1 266128 266283 D hypothetical protein 266128..266283 Actinosynnema mirum DSM 43827 8324397 YP_003098056.1 CDS Amir_0241 NC_013093.1 266280 266738 D PFAM: endoribonuclease L-PSP; KEGG: rce:RC1_1921 endoribonuclease L-PSP; endoribonuclease L-PSP 266280..266738 Actinosynnema mirum DSM 43827 8324398 YP_003098057.1 CDS Amir_0242 NC_013093.1 266740 267351 D hypothetical protein 266740..267351 Actinosynnema mirum DSM 43827 8324399 YP_003098058.1 CDS Amir_0243 NC_013093.1 267390 268634 D KEGG: predicted protein; hypothetical protein 267390..268634 Actinosynnema mirum DSM 43827 8324400 YP_003098059.1 CDS Amir_0244 NC_013093.1 268651 269457 R KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein complement(268651..269457) Actinosynnema mirum DSM 43827 8324401 YP_003098060.1 CDS Amir_0245 NC_013093.1 269454 270344 R PFAM: oxidoreductase domain protein; KEGG: rec:RHECIAT_PC0000780 oxidoreductase protein; oxidoreductase domain-containing protein complement(269454..270344) Actinosynnema mirum DSM 43827 8324402 YP_003098061.1 CDS Amir_0246 NC_013093.1 270356 270715 R hypothetical protein complement(270356..270715) Actinosynnema mirum DSM 43827 8324403 YP_003098062.1 CDS Amir_0247 NC_013093.1 270739 271578 D PFAM: NUDIX hydrolase; KEGG: rpd:RPD_3111 NUDIX hydrolase; NUDIX hydrolase 270739..271578 Actinosynnema mirum DSM 43827 8324404 YP_003098063.1 CDS Amir_0248 NC_013093.1 271575 272375 D PFAM: beta-lactamase domain protein; KEGG: aav:Aave_0793 beta-lactamase domain protein; beta-lactamase domain-containing protein 271575..272375 Actinosynnema mirum DSM 43827 8324405 YP_003098064.1 CDS Amir_0249 NC_013093.1 272493 273131 D KEGG: mlo:mlr3017 5'-nucleotidase; hypothetical protein 272493..273131 Actinosynnema mirum DSM 43827 8324406 YP_003098065.1 CDS Amir_0250 NC_013093.1 273148 273483 R hypothetical protein complement(273148..273483) Actinosynnema mirum DSM 43827 8324407 YP_003098066.1 CDS Amir_0251 NC_013093.1 273605 274702 R KEGG: sus:Acid_0002 DNA polymerase III subunit beta; TIGRFAM: DNA polymerase III subunit beta; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain; DNA polymerase III subunit beta complement(273605..274702) Actinosynnema mirum DSM 43827 8324408 YP_003098067.1 CDS Amir_0252 NC_013093.1 274744 276042 R PFAM: major facilitator superfamily MFS_1; KEGG: sml:Smlt0548 MFS family transporter; major facilitator superfamily protein complement(274744..276042) Actinosynnema mirum DSM 43827 8324409 YP_003098068.1 CDS Amir_0253 NC_013093.1 276747 277421 R PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: bbt:BBta_5745 transcriptional regulator; Crp/Fnr family transcriptional regulator complement(276747..277421) Actinosynnema mirum DSM 43827 8324410 YP_003098069.1 CDS Amir_0254 NC_013093.1 277624 277872 R hypothetical protein complement(277624..277872) Actinosynnema mirum DSM 43827 8324411 YP_003098070.1 CDS Amir_0255 NC_013093.1 278144 278917 D KEGG: pca:Pcar_0009 endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop; endonuclease III 278144..278917 Actinosynnema mirum DSM 43827 8324412 YP_003098071.1 CDS Amir_0256 NC_013093.1 278914 279594 D PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: xop:PXO_04554 thioredoxin; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 278914..279594 Actinosynnema mirum DSM 43827 8324413 YP_003098072.1 CDS Amir_0257 NC_013093.1 279591 280331 D PFAM: NUDIX hydrolase; KEGG: mch:Mchl_1739 NUDIX hydrolase; NUDIX hydrolase 279591..280331 Actinosynnema mirum DSM 43827 8324414 YP_003098073.1 CDS Amir_0258 NC_013093.1 280353 281540 D PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; Colicin V production protein 280353..281540 Actinosynnema mirum DSM 43827 8324415 YP_003098074.1 CDS Amir_0259 NC_013093.1 281588 282514 R PFAM: alpha/beta hydrolase fold; KEGG: acp:A2cp1_0551 alpha/beta hydrolase fold protein; alpha/beta hydrolase fold protein complement(281588..282514) Actinosynnema mirum DSM 43827 8324416 YP_003098075.1 CDS Amir_0260 NC_013093.1 282523 282990 R PFAM: protein of unknown function DUF1469; KEGG: mpo:Mpop_1689 protein of unknown function DUF1469; hypothetical protein complement(282523..282990) Actinosynnema mirum DSM 43827 8324417 YP_003098076.1 CDS Amir_0261 NC_013093.1 283062 284234 R TIGRFAM: Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter NhaA; sodium/hydrogen exchanger; KEGG: mlo:mlr5309 Na+/H+ antiporter; Na+/H+ antiporter NhaA complement(283062..284234) Actinosynnema mirum DSM 43827 8324418 YP_003098077.1 CDS Amir_0262 NC_013093.1 284370 286355 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(284370..286355) Actinosynnema mirum DSM 43827 8324419 YP_003098078.1 CDS Amir_0263 NC_013093.1 286579 287160 R PFAM: GCN5-related N-acetyltransferase; KEGG: aav:Aave_3953 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(286579..287160) Actinosynnema mirum DSM 43827 8324420 YP_003098079.1 CDS Amir_0264 NC_013093.1 287252 287974 D KEGG: mxa:MXAN_6904 hypothetical protein; hypothetical protein 287252..287974 Actinosynnema mirum DSM 43827 8324421 YP_003098080.1 CDS Amir_0265 NC_013093.1 287971 289092 R TIGRFAM: kynureninase; PFAM: aminotransferase class V; KEGG: pde:Pden_2620 kynureninase; kynureninase complement(287971..289092) Actinosynnema mirum DSM 43827 8324422 YP_003098081.1 CDS Amir_0266 NC_013093.1 289089 289910 R PFAM: tryptophan 23-dioxygenase; KEGG: reh:H16_B1418 tryptophan 2,3-dioxygenase; tryptophan 23-dioxygenase complement(289089..289910) Actinosynnema mirum DSM 43827 8324423 YP_003098082.1 CDS Amir_0267 NC_013093.1 290017 290466 D PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: bam:Bamb_3888 AsnC family transcriptional regulator; AsnC family transcriptional regulator 290017..290466 Actinosynnema mirum DSM 43827 8324424 YP_003098083.1 CDS murQ NC_013093.1 290435 291361 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase complement(290435..291361) Actinosynnema mirum DSM 43827 8324425 YP_003098084.1 CDS Amir_0269 NC_013093.1 291358 292272 R PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: reh:H16_B1066 transcriptional regulator; RpiR family transcriptional regulator complement(291358..292272) Actinosynnema mirum DSM 43827 8324426 YP_003098085.1 CDS Amir_0270 NC_013093.1 292383 294536 R PFAM: beta-lactamase; KEGG: beta-lactamase; beta-lactamase complement(292383..294536) Actinosynnema mirum DSM 43827 8324427 YP_003098086.1 CDS Amir_0271 NC_013093.1 294549 295880 R PFAM: conserved hypothetical protein; KEGG: hypothetical protein; hypothetical protein complement(294549..295880) Actinosynnema mirum DSM 43827 8324428 YP_003098087.1 CDS Amir_0272 NC_013093.1 295935 296138 R KEGG: similar to mucin 17; hypothetical protein complement(295935..296138) Actinosynnema mirum DSM 43827 8324429 YP_003098088.1 CDS Amir_0273 NC_013093.1 296355 298097 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: bha:BH0675 beta-hexosamidase A precursor; glycoside hydrolase family protein complement(296355..298097) Actinosynnema mirum DSM 43827 8324430 YP_003098089.1 CDS Amir_0274 NC_013093.1 298682 299494 R TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase- like); KEGG: pap:PSPA7_0428 hypothetical protein; HAD superfamily hydrolase complement(298682..299494) Actinosynnema mirum DSM 43827 8324431 YP_003098090.1 CDS Amir_0275 NC_013093.1 299900 301015 D KEGG: ank:AnaeK_2914 Flp pilus assembly protein ATPase CpaE-like protein; hypothetical protein 299900..301015 Actinosynnema mirum DSM 43827 8324432 YP_003098091.1 CDS Amir_0276 NC_013093.1 301321 302439 D PFAM: type II secretion system protein E; KEGG: bav:BAV2285 pilus assembly protein; type II secretion system protein E 301321..302439 Actinosynnema mirum DSM 43827 8324433 YP_003098092.1 CDS Amir_0277 NC_013093.1 302579 303334 D PFAM: type II secretion system protein; KEGG: acp:A2cp1_3010 type II secretion system protein; type II secretion system protein 302579..303334 Actinosynnema mirum DSM 43827 8324434 YP_003098093.1 CDS Amir_0278 NC_013093.1 303331 303888 D PFAM: type II secretion system protein; KEGG: Hcn2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; K04955 hyperpolarization activated cyclic nucleotide-gated potassium channel 2; type II secretion system protein 303331..303888 Actinosynnema mirum DSM 43827 8324435 YP_003098094.1 CDS Amir_0279 NC_013093.1 303910 304065 D hypothetical protein 303910..304065 Actinosynnema mirum DSM 43827 8324436 YP_003098095.1 CDS Amir_0280 NC_013093.1 304062 304478 D hypothetical protein 304062..304478 Actinosynnema mirum DSM 43827 8324437 YP_003098096.1 CDS Amir_0281 NC_013093.1 304605 304934 D KEGG: nwi:Nwi_2535 hypothetical protein; hypothetical protein 304605..304934 Actinosynnema mirum DSM 43827 8324438 YP_003098097.1 CDS Amir_0282 NC_013093.1 305305 305910 D PFAM: Bifunctional DNA primase/polymerase; Bifunctional DNA primase/polymerase 305305..305910 Actinosynnema mirum DSM 43827 8324439 YP_003098098.1 CDS Amir_0283 NC_013093.1 306276 308699 R PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: dvu:DVU0256 DEAD-box ATP dependent DNA helicase; DEAD/DEAH box helicase domain-containing protein complement(306276..308699) Actinosynnema mirum DSM 43827 8324440 YP_003098099.1 CDS hppA NC_013093.1 308935 311295 D pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 308935..311295 Actinosynnema mirum DSM 43827 8324441 YP_003098100.1 CDS Amir_0285 NC_013093.1 311416 312054 D KEGG: hypothetical protein; hypothetical protein 311416..312054 Actinosynnema mirum DSM 43827 8324442 YP_003098101.1 CDS Amir_0286 NC_013093.1 312083 312202 D hypothetical protein 312083..312202 Actinosynnema mirum DSM 43827 8324443 YP_003098102.1 CDS Amir_0287 NC_013093.1 312321 312962 D KEGG: bac:BamMC406_1732 peptidase M23; hypothetical protein 312321..312962 Actinosynnema mirum DSM 43827 8324444 YP_003098103.1 CDS Amir_0288 NC_013093.1 313088 313771 D KEGG: YALI0D24365p; hypothetical protein 313088..313771 Actinosynnema mirum DSM 43827 8324445 YP_003098104.1 CDS Amir_0289 NC_013093.1 313913 314566 D KEGG: mucin-associated surface protein (MASP); hypothetical protein 313913..314566 Actinosynnema mirum DSM 43827 8324446 YP_003098105.1 CDS Amir_0290 NC_013093.1 314696 315328 D KEGG: swi:Swit_0780 branched-chain alpha-keto acid dehydrogenase E2 component; hypothetical protein 314696..315328 Actinosynnema mirum DSM 43827 8324447 YP_003098106.1 CDS Amir_0291 NC_013093.1 315457 318228 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 315457..318228 Actinosynnema mirum DSM 43827 8324448 YP_003098107.1 CDS Amir_0292 NC_013093.1 318252 318821 D KEGG: hypothetical protein; hypothetical protein 318252..318821 Actinosynnema mirum DSM 43827 8324449 YP_003098108.1 CDS Amir_0293 NC_013093.1 318901 321033 D PFAM: major facilitator superfamily MFS_1; thymidylate kinase; KEGG: eli:ELI_06215 thymidylate kinase; major facilitator superfamily protein 318901..321033 Actinosynnema mirum DSM 43827 8324450 YP_003098109.1 CDS Amir_0294 NC_013093.1 321047 322246 D KEGG: dal:Dalk_0024 DNA-directed DNA polymerase; DNA-directed DNA polymerase 321047..322246 Actinosynnema mirum DSM 43827 8324451 YP_003098110.1 CDS Amir_0295 NC_013093.1 322756 323649 D PFAM: glycosyl transferase family 2; KEGG: dal:Dalk_4823 glycosyl transferase family 2; family 2 glycosyl transferase 322756..323649 Actinosynnema mirum DSM 43827 8324453 YP_003098111.1 CDS Amir_0296 NC_013093.1 323703 325736 R part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit complement(323703..325736) Actinosynnema mirum DSM 43827 8324454 YP_003098112.1 CDS Amir_0297 NC_013093.1 325736 326707 R PFAM: periplasmic binding protein; KEGG: bcb:BCB4264_A4636 iron compound ABC transporter, iron compound-binding protein; periplasmic binding protein complement(325736..326707) Actinosynnema mirum DSM 43827 8324455 YP_003098113.1 CDS Amir_0298 NC_013093.1 326738 327556 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ent:Ent638_1120 iron-enterobactin transporter ATP-binding protein; ABC transporter complement(326738..327556) Actinosynnema mirum DSM 43827 8324456 YP_003098114.1 CDS Amir_0299 NC_013093.1 328007 328162 D hypothetical protein 328007..328162 Actinosynnema mirum DSM 43827 8324457 YP_003098115.1 CDS Amir_0300 NC_013093.1 328149 329243 R PFAM: luciferase-like monooxygenase; KEGG: swi:Swit_1615 coenzyme F420-dependent N5 N10- methylene tetrahydromethanopterin reductase-like protein; luciferase-like monooxygenase complement(328149..329243) Actinosynnema mirum DSM 43827 8324458 YP_003098116.1 CDS Amir_0301 NC_013093.1 329240 329704 R PFAM: Excalibur domain protein; KEGG: GE20613 gene product from transcript GE20613- RA; Excalibur domain-containing protein complement(329240..329704) Actinosynnema mirum DSM 43827 8324459 YP_003098117.1 CDS Amir_0302 NC_013093.1 329694 330653 R PFAM: Excalibur domain protein; KEGG: sal:Sala_0134 excalibur; Excalibur domain-containing protein complement(329694..330653) Actinosynnema mirum DSM 43827 8324460 YP_003098118.1 CDS Amir_0303 NC_013093.1 330650 331321 R PFAM: nuclease (SNase domain protein); SMART: nuclease (SNase domain protein); KEGG: mno:Mnod_4939 hypothetical protein; nuclease complement(330650..331321) Actinosynnema mirum DSM 43827 8324461 YP_003098119.1 CDS Amir_0304 NC_013093.1 331443 331889 R KEGG: pzu:PHZ_c1913 hypothetical protein; hypothetical protein complement(331443..331889) Actinosynnema mirum DSM 43827 8324462 YP_003098120.1 CDS Amir_0305 NC_013093.1 332019 332537 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: atc:AGR_C_1531 hypothetical protein; MarR family transcriptional regulator 332019..332537 Actinosynnema mirum DSM 43827 8324463 YP_003098121.1 CDS Amir_0306 NC_013093.1 332537 334204 D TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ppg:PputGB1_3285 EmrB/QacA family drug resistance transporter; EmrB/QacA subfamily drug resistance transporter 332537..334204 Actinosynnema mirum DSM 43827 8324464 YP_003098122.1 CDS Amir_0307 NC_013093.1 334313 334816 R PFAM: inorganic pyrophosphatase; KEGG: gdi:GDI3491 inorganic pyrophosphatase; inorganic diphosphatase complement(334313..334816) Actinosynnema mirum DSM 43827 8324465 YP_003098123.1 CDS Amir_0308 NC_013093.1 334943 337993 D TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D- alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; KEGG: bpm:BURPS1710b_1102 lipoprotein; D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D- alanine-endopeptidase 334943..337993 Actinosynnema mirum DSM 43827 8324466 YP_003098124.1 CDS Amir_0309 NC_013093.1 338032 339045 D hypothetical protein 338032..339045 Actinosynnema mirum DSM 43827 8324467 YP_003098125.1 CDS Amir_0310 NC_013093.1 339042 339968 D TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: ade:Adeh_1494 tRNA(Ile)-lysidine synthetase- like; tRNA(Ile)-lysidine synthetase 339042..339968 Actinosynnema mirum DSM 43827 8324468 YP_003098126.1 CDS Amir_0311 NC_013093.1 339985 340533 D KEGG: spe:Spro_3998 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 339985..340533 Actinosynnema mirum DSM 43827 8324469 YP_003098127.1 CDS Amir_0312 NC_013093.1 340597 342291 R PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: dac:Daci_0766 von Willebrand factor type A; von Willebrand factor type A complement(340597..342291) Actinosynnema mirum DSM 43827 8324470 YP_003098128.1 CDS Amir_0313 NC_013093.1 342757 344988 D KEGG: bcy:Bcer98_0060 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; peptidase M41 FtsH extracellular; ATPase AAA; SMART: ATPase AAA; ATP-dependent metalloprotease FtsH 342757..344988 Actinosynnema mirum DSM 43827 8324471 YP_003098129.1 CDS Amir_0314 NC_013093.1 344985 345614 D KEGG: bha:BH1646 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; GTP cyclohydrolase I 344985..345614 Actinosynnema mirum DSM 43827 8324472 YP_003098130.1 CDS Amir_0315 NC_013093.1 345653 346438 D KEGG: afw:Anae109_2337 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; dihydropteroate synthase 345653..346438 Actinosynnema mirum DSM 43827 8324473 YP_003098131.1 CDS Amir_0316 NC_013093.1 346431 346808 D TIGRFAM: dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase; KEGG: oca:OCAR_6643 dihydroneopterin aldolase; dihydroneopterin aldolase 346431..346808 Actinosynnema mirum DSM 43827 8324474 YP_003098132.1 CDS Amir_0317 NC_013093.1 346805 347281 D KEGG: mex:Mext_1812 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase 346805..347281 Actinosynnema mirum DSM 43827 8324475 YP_003098133.1 CDS Amir_0318 NC_013093.1 347278 347730 D KEGG: afw:Anae109_2860 cytochrome C oxidase subunit III; hypothetical protein 347278..347730 Actinosynnema mirum DSM 43827 8324476 YP_003098134.1 CDS Amir_0319 NC_013093.1 347781 349451 D KEGG: mgm:Mmc1_2162 hypothetical protein; hypothetical protein 347781..349451 Actinosynnema mirum DSM 43827 8324477 YP_003098135.1 CDS Amir_0320 NC_013093.1 349936 351012 R PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: bcz:BCZK4997 NADH dehydrogenase subunit D; NADH dehydrogenase (quinone) complement(349936..351012) Actinosynnema mirum DSM 43827 8324478 YP_003098136.1 CDS Amir_0321 NC_013093.1 351017 351454 R PFAM: protein of unknown function DUF1203; KEGG: rle:RL1972 hypothetical protein; hypothetical protein complement(351017..351454) Actinosynnema mirum DSM 43827 8324479 YP_003098137.1 CDS Amir_0322 NC_013093.1 351540 352457 D PFAM: protein of unknown function DUF185; KEGG: lch:Lcho_0104 hypothetical protein; hypothetical protein 351540..352457 Actinosynnema mirum DSM 43827 8324480 YP_003098138.1 CDS Amir_0323 NC_013093.1 352527 353855 D KEGG: scl:sce5075 hypothetical protein; hypothetical protein 352527..353855 Actinosynnema mirum DSM 43827 8324481 YP_003098139.1 CDS Amir_0324 NC_013093.1 353944 354837 D KEGG: sat:SYN_02774 cytoplasmic protein; cytoplasmic protein 353944..354837 Actinosynnema mirum DSM 43827 8324482 YP_003098140.1 CDS panC NC_013093.1 354841 355731 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 354841..355731 Actinosynnema mirum DSM 43827 8324483 YP_003098141.1 CDS Amir_0326 NC_013093.1 355746 356216 D KEGG: bcb:BCB4264_A1597 aspartate 1-decarboxylase; TIGRFAM: aspartate 1-decarboxylase; PFAM: aspartate decarboxylase; aspartate 1-decarboxylase 355746..356216 Actinosynnema mirum DSM 43827 8324484 YP_003098142.1 CDS Amir_0327 NC_013093.1 356227 357012 D TIGRFAM: transcriptional activator, Baf family; PFAM: Bvg accessory factor; KEGG: ank:AnaeK_1477 transcriptional acitvator, Baf family; transcriptional acitvator, Baf family 356227..357012 Actinosynnema mirum DSM 43827 8324485 YP_003098143.1 CDS Amir_0328 NC_013093.1 357087 357866 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mno:Mnod_8065 methyltransferase type 11; type 11 methyltransferase complement(357087..357866) Actinosynnema mirum DSM 43827 8324486 YP_003098144.1 CDS Amir_0329 NC_013093.1 357929 359440 D TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dal:Dalk_1784 lysyl-tRNA synthetase; lysyl-tRNA synthetase 357929..359440 Actinosynnema mirum DSM 43827 8324487 YP_003098145.1 CDS Amir_0330 NC_013093.1 359559 359909 D hypothetical protein 359559..359909 Actinosynnema mirum DSM 43827 8324488 YP_003098146.1 CDS Amir_0331 NC_013093.1 360226 361230 D PFAM: transport system permease protein; KEGG: pde:Pden_3523 transport system permease protein; transport system permease 360226..361230 Actinosynnema mirum DSM 43827 8324489 YP_003098147.1 CDS Amir_0332 NC_013093.1 361227 362411 D PFAM: transport system permease protein; KEGG: ppg:PputGB1_1806 transport system permease protein; transport system permease 361227..362411 Actinosynnema mirum DSM 43827 8324490 YP_003098148.1 CDS Amir_0333 NC_013093.1 362408 363256 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cvi:CV_2234 enterobactin-iron transport system ATP-binding protein; ABC transporter 362408..363256 Actinosynnema mirum DSM 43827 8324491 YP_003098149.1 CDS Amir_0334 NC_013093.1 363284 364099 R KEGG: hypothetical protein; hypothetical protein complement(363284..364099) Actinosynnema mirum DSM 43827 8324492 YP_003098150.1 CDS Amir_0335 NC_013093.1 364370 366928 D PFAM: ATPase AAA; ATPase AAA; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA; KEGG: bha:BH0103 class III stress response-related ATPase; ATPase AAA 364370..366928 Actinosynnema mirum DSM 43827 8324493 YP_003098151.1 CDS Amir_0336 NC_013093.1 367074 367718 R KEGG: saz:Sama_0018 pyroglutamyl-peptidase I; TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15 pyroglutamyl peptidase I; pyrrolidone-carboxylate peptidase complement(367074..367718) Actinosynnema mirum DSM 43827 8324494 YP_003098152.1 CDS Amir_0337 NC_013093.1 367737 368708 D PFAM: endonuclease/exonuclease/phosphatase; KEGG: afw:Anae109_1227 endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 367737..368708 Actinosynnema mirum DSM 43827 8324495 YP_003098153.1 CDS Amir_0338 NC_013093.1 368769 369539 R PFAM: Silent information regulator protein Sir2; KEGG: afw:Anae109_4302 silent information regulator protein Sir2; Silent information regulator protein Sir2 complement(368769..369539) Actinosynnema mirum DSM 43827 8324496 YP_003098154.1 CDS Amir_0339 NC_013093.1 369553 369864 R PFAM: Antibiotic biosynthesis monooxygenase; KEGG: afr:AFE_2662 antibiotic biosynthesis monooxygenase family protein; Antibiotic biosynthesis monooxygenase complement(369553..369864) Actinosynnema mirum DSM 43827 8324497 YP_003098155.1 CDS Amir_0340 NC_013093.1 369874 371352 R PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: mxa:MXAN_0644 peptidase, M1 (aminopeptidase N) family; peptidase M1 membrane alanine aminopeptidase complement(369874..371352) Actinosynnema mirum DSM 43827 8324498 YP_003098156.1 CDS Amir_0341 NC_013093.1 371370 372116 D PFAM: alpha/beta hydrolase fold; KEGG: ppg:PputGB1_4047 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 371370..372116 Actinosynnema mirum DSM 43827 8324499 YP_003098157.1 CDS Amir_0342 NC_013093.1 372065 372571 R hypothetical protein complement(372065..372571) Actinosynnema mirum DSM 43827 8324500 YP_003098158.1 CDS Amir_0343 NC_013093.1 372629 373618 R PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; KEGG: scl:sce3935 A/G-specific adenine glycosylase; HhH-GPD family protein complement(372629..373618) Actinosynnema mirum DSM 43827 8324501 YP_003098159.1 CDS Amir_0344 NC_013093.1 373677 374168 R PFAM: carbonic anhydrase; KEGG: aba:Acid345_1601 carbonic anhydrase; carbonic anhydrase complement(373677..374168) Actinosynnema mirum DSM 43827 8324502 YP_003098160.1 CDS Amir_0345 NC_013093.1 374248 375048 D KEGG: hypothetical protein; K05747 Wiskott-Aldrich syndrome protein; hypothetical protein 374248..375048 Actinosynnema mirum DSM 43827 8324503 YP_003098161.1 CDS Amir_0346 NC_013093.1 375152 376255 R PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: gox:GOX0577 transcriptional regulator; LacI family transcriptional regulator complement(375152..376255) Actinosynnema mirum DSM 43827 8324504 YP_003098162.1 CDS Amir_0347 NC_013093.1 376377 377420 R KEGG: pen:PSEEN1955 ribose operon repressor RbsR; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(376377..377420) Actinosynnema mirum DSM 43827 8324505 YP_003098163.1 CDS Amir_0348 NC_013093.1 377686 378945 D PFAM: extracellular solute-binding protein family 1; KEGG: oan:Oant_3895 extracellular solute-binding protein family 1; family 1 extracellular solute-binding protein 377686..378945 Actinosynnema mirum DSM 43827 8324506 YP_003098164.1 CDS Amir_0349 NC_013093.1 379013 379930 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ade:Adeh_4135 ABC sugar transporter, inner membrane subunit; sugar ABC transporter inner membrane protein 379013..379930 Actinosynnema mirum DSM 43827 8324507 YP_003098165.1 CDS Amir_0350 NC_013093.1 379930 380823 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: acp:A2cp1_4287 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 379930..380823 Actinosynnema mirum DSM 43827 8324508 YP_003098166.1 CDS Amir_0351 NC_013093.1 380907 382007 D PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: rlt:Rleg2_5484 ABC transporter; ABC transporter 380907..382007 Actinosynnema mirum DSM 43827 8324509 YP_003098167.1 CDS Amir_0352 NC_013093.1 382167 383057 D PFAM: periplasmic solute binding protein; KEGG: bpy:Bphyt_0292 periplasmic solute binding protein; periplasmic solute binding protein 382167..383057 Actinosynnema mirum DSM 43827 8324510 YP_003098168.1 CDS Amir_0353 NC_013093.1 383054 383896 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bvi:Bcep1808_2715 ABC transporter; ABC transporter 383054..383896 Actinosynnema mirum DSM 43827 8324511 YP_003098169.1 CDS Amir_0354 NC_013093.1 383896 384732 D PFAM: ABC transporter; KEGG: bxe:Bxe_A0715 ABC Mn2+/Zn2+ transporter, inner membrane subunit; ABC transporter 383896..384732 Actinosynnema mirum DSM 43827 8324512 YP_003098170.1 CDS Amir_0355 NC_013093.1 384876 386333 R KEGG: cvi:CV_3252 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase complement(384876..386333) Actinosynnema mirum DSM 43827 8324513 YP_003098171.1 CDS Amir_0356 NC_013093.1 386565 387788 R PFAM: major facilitator superfamily MFS_1; KEGG: reh:H16_B2569 MFS transporter; major facilitator superfamily protein complement(386565..387788) Actinosynnema mirum DSM 43827 8324514 YP_003098172.1 CDS Amir_0357 NC_013093.1 388223 388399 D hypothetical protein 388223..388399 Actinosynnema mirum DSM 43827 8324515 YP_003098173.1 CDS Amir_0358 NC_013093.1 388670 390100 R PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: ppw:PputW619_0881 membrane bound O-acyl transferase MBOAT family protein; membrane bound O-acyl transferase MBOAT family protein complement(388670..390100) Actinosynnema mirum DSM 43827 8324516 YP_003098174.1 CDS Amir_0359 NC_013093.1 390193 391158 R TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: afw:Anae109_2230 RNA methyltransferase; TrmH family RNA methyltransferase complement(390193..391158) Actinosynnema mirum DSM 43827 8324517 YP_003098175.1 CDS cysS NC_013093.1 391164 392558 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(391164..392558) Actinosynnema mirum DSM 43827 8324518 YP_003098176.1 CDS Amir_0361 NC_013093.1 392625 393236 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: haloacid dehalogenase-like hydrolase family protein; HAD superfamily hydrolase complement(392625..393236) Actinosynnema mirum DSM 43827 8324519 YP_003098177.1 CDS Amir_0362 NC_013093.1 393471 393938 R KEGG: eli:ELI_06290 bifunctional 2-C-methyl-D- erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D- erythritol 2,4-cyclodiphosphate synthase protein; TIGRFAM: 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase; PFAM: MECDP-synthase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(393471..393938) Actinosynnema mirum DSM 43827 8324520 YP_003098178.1 CDS Amir_0363 NC_013093.1 393935 394627 R TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: bcr:BCAH187_A0116 2-C-methyl-D-erythritol 4- phosphate cytidylyltransferase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(393935..394627) Actinosynnema mirum DSM 43827 8324521 YP_003098179.1 CDS Amir_0364 NC_013093.1 394663 395151 R PFAM: transcription factor CarD; KEGG: bcb:BCB4264_A4827 transcriptional regulator, CarD family; CarD family transcriptional regulator complement(394663..395151) Actinosynnema mirum DSM 43827 8324522 YP_003098180.1 CDS Amir_0365 NC_013093.1 395536 396153 D KEGG: YALI0C03894p; hypothetical protein 395536..396153 Actinosynnema mirum DSM 43827 8324523 YP_003098181.1 CDS Amir_0366 NC_013093.1 396591 397979 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 396591..397979 Actinosynnema mirum DSM 43827 8324524 YP_003098182.1 CDS Amir_0367 NC_013093.1 398370 399224 R SMART: helix-turn-helix domain protein; KEGG: bur:Bcep18194_B2467 XRE family transcriptional regulator; helix-turn-helix domain-containing protein complement(398370..399224) Actinosynnema mirum DSM 43827 8324525 YP_003098183.1 CDS Amir_0368 NC_013093.1 399383 400234 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: reh:H16_B1910 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 399383..400234 Actinosynnema mirum DSM 43827 8324526 YP_003098184.1 CDS Amir_0370 NC_013093.1 400639 403167 R TIGRFAM: trehalose-phosphatase; HAD-superfamily hydrolase, subfamily IIB; PFAM: glycoside hydrolase 15-related; trehalose- phosphatase; KEGG: nmu:Nmul_A2309 glycoside hydrolase 15-like protein; trehalose-phosphatase complement(400639..403167) Actinosynnema mirum DSM 43827 8324528 YP_003098185.1 CDS Amir_0371 NC_013093.1 403246 404682 R PFAM: glycosyl transferase family 20; KEGG: scl:sce0488 alpha,alpha-trehalose-phosphate synthase (UDP-forming); alpha,alpha-trehalose-phosphate synthase complement(403246..404682) Actinosynnema mirum DSM 43827 8324529 YP_003098186.1 CDS Amir_0372 NC_013093.1 404791 406185 R PFAM: protein of unknown function DUF1212; KEGG: rpt:Rpal_1546 protein of unknown function DUF1212; hypothetical protein complement(404791..406185) Actinosynnema mirum DSM 43827 8324530 YP_003098187.1 CDS Amir_0374 NC_013093.1 407108 408085 D SMART: regulatory protein ArsR; KEGG: ajs:Ajs_2855 ArsR family transcriptional regulator; ArsR family transcriptional regulator 407108..408085 Actinosynnema mirum DSM 43827 8324533 YP_003098188.1 CDS Amir_0375 NC_013093.1 408188 409822 R PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(408188..409822) Actinosynnema mirum DSM 43827 8324534 YP_003098189.1 CDS Amir_0376 NC_013093.1 409989 411551 R PFAM: chemotaxis sensory transducer; GAF domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer with GAF sensor complement(409989..411551) Actinosynnema mirum DSM 43827 8324535 YP_003098190.1 CDS Amir_0377 NC_013093.1 411724 413376 R PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: mxa:MXAN_6334 hypothetical protein; von Willebrand factor type A complement(411724..413376) Actinosynnema mirum DSM 43827 8324536 YP_003098191.1 CDS Amir_0378 NC_013093.1 413875 415284 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase complement(413875..415284) Actinosynnema mirum DSM 43827 8324537 YP_003098192.1 CDS Amir_0379 NC_013093.1 415284 415985 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bat:BAS2056 DNA-binding response regulator; winged helix family two component transcriptional regulator complement(415284..415985) Actinosynnema mirum DSM 43827 8324538 YP_003098193.1 CDS Amir_0380 NC_013093.1 416139 417482 D PFAM: Ferric reductase domain protein transmembrane component domain; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; FAD-binding 8 domain protein; KEGG: ank:AnaeK_0310 oxidoreductase FAD/NAD(P)- binding domain protein; ferric reductase transmembrane domain-containing protein 416139..417482 Actinosynnema mirum DSM 43827 8324539 YP_003098194.1 CDS Amir_0381 NC_013093.1 417520 417927 D PFAM: FMN-binding domain protein; KEGG: mlo:mll6621 hypothetical protein; FMN-binding domain-containing protein 417520..417927 Actinosynnema mirum DSM 43827 8324540 YP_003098195.1 CDS Amir_0382 NC_013093.1 417932 418645 D PFAM: ApbE family lipoprotein; KEGG: mlo:mll6620 thiamine biosynthesis lipoprotein; ApbE family lipoprotein 417932..418645 Actinosynnema mirum DSM 43827 8324541 YP_003098196.1 CDS Amir_0383 NC_013093.1 418924 419154 R hypothetical protein complement(418924..419154) Actinosynnema mirum DSM 43827 8324542 YP_003098197.1 CDS Amir_0384 NC_013093.1 419414 420451 R PFAM: ADP-ribosylation/Crystallin J1; KEGG: dol:Dole_0265 ADP-ribosylation/crystallin J1; ADP-ribosylation/Crystallin J1 complement(419414..420451) Actinosynnema mirum DSM 43827 8324543 YP_003098198.1 CDS Amir_0385 NC_013093.1 420623 423445 D PFAM: transcriptional activator domain; NB-ARC domain protein; transcriptional regulator domain protein; KEGG: scl:sce8759 hypothetical protein; SARP family transcriptional regulator 420623..423445 Actinosynnema mirum DSM 43827 8324544 YP_003098199.1 CDS Amir_0386 NC_013093.1 423636 424412 R PFAM: lipolytic protein G-D-S-L family; KEGG: bcb:BCB4264_A2458 hypothetical protein; G-D-S-L family lipolytic protein complement(423636..424412) Actinosynnema mirum DSM 43827 8324545 YP_003098200.1 CDS Amir_0387 NC_013093.1 424515 424955 R hypothetical protein complement(424515..424955) Actinosynnema mirum DSM 43827 8324546 YP_003098201.1 CDS Amir_0388 NC_013093.1 425108 425854 D hypothetical protein 425108..425854 Actinosynnema mirum DSM 43827 8324547 YP_003098202.1 CDS Amir_0389 NC_013093.1 425911 426903 R PFAM: luciferase-like monooxygenase; KEGG: sme:SM_b21003 oxidoreductase protein; luciferase-like monooxygenase complement(425911..426903) Actinosynnema mirum DSM 43827 8324548 YP_003098203.1 CDS Amir_0390 NC_013093.1 427020 427901 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: acr:Acry_2830 LysR family transcriptional regulator; LysR family transcriptional regulator 427020..427901 Actinosynnema mirum DSM 43827 8324549 YP_003098204.1 CDS Amir_0391 NC_013093.1 428065 429006 R PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: slo:Shew_1116 ATPase, BadF/BadG/BcrA/BcrD type; BadF/BadG/BcrA/BcrD type ATPase complement(428065..429006) Actinosynnema mirum DSM 43827 8324550 YP_003098205.1 CDS Amir_0392 NC_013093.1 429003 432230 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: glo:Glov_1721 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin complement(429003..432230) Actinosynnema mirum DSM 43827 8324551 YP_003098206.1 CDS Amir_0393 NC_013093.1 432351 433205 D PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rle:RL0016 FAA hydrolase family protein; 5-oxopent-3-ene-1,2, 5-tricarboxylatedecarboxylase 432351..433205 Actinosynnema mirum DSM 43827 8324552 YP_003098207.1 CDS Amir_0394 NC_013093.1 433205 434617 D PFAM: mandelate racemase/muconate lactonizing protein; KEGG: xca:xccb100_4271 phosphopyruvate hydratase; mandelate racemase/muconate lactonizing protein 433205..434617 Actinosynnema mirum DSM 43827 8324553 YP_003098208.1 CDS Amir_0395 NC_013093.1 434593 435363 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bpe:BP1923 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 434593..435363 Actinosynnema mirum DSM 43827 8324554 YP_003098209.1 CDS Amir_0396 NC_013093.1 435360 436289 D PFAM: aldo/keto reductase; KEGG: xac:XAC4184 oxidoreductase; aldo/keto reductase 435360..436289 Actinosynnema mirum DSM 43827 8324555 YP_003098210.1 CDS Amir_0397 NC_013093.1 436286 437110 D PFAM: amidohydrolase 2; KEGG: mes:Meso_1610 amidohydrolase 2; amidohydrolase 2 436286..437110 Actinosynnema mirum DSM 43827 8324556 YP_003098211.1 CDS Amir_0398 NC_013093.1 437177 438277 D PFAM: beta-lactamase; KEGG: bcz:pE33L466_0099 D-stereospecific peptide hydrolase; Serine-type D-Ala-D-Ala carboxypeptidase 437177..438277 Actinosynnema mirum DSM 43827 8324557 YP_003098212.1 CDS Amir_0399 NC_013093.1 438344 439018 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: csa:Csal_0365 transcriptional regulator, GntR family; GntR family transcriptional regulator complement(438344..439018) Actinosynnema mirum DSM 43827 8324558 YP_003098213.1 CDS Amir_0400 NC_013093.1 439140 440183 R PFAM: sugar isomerase (SIS); KEGG: sus:Acid_1598 glutamine--fructose-6-phosphate transaminase (isomerizing); glutamine--fructose-6-phosphate transaminase complement(439140..440183) Actinosynnema mirum DSM 43827 8324559 YP_003098214.1 CDS Amir_0401 NC_013093.1 440530 441351 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_3555 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane proteint complement(440530..441351) Actinosynnema mirum DSM 43827 8324560 YP_003098215.1 CDS Amir_0402 NC_013093.1 441348 442340 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bxe:Bxe_B0419 ABC sugar transporter, inner membrane subunit; sugar ABC transporter inner membrane protein complement(441348..442340) Actinosynnema mirum DSM 43827 8324561 YP_003098216.1 CDS Amir_0403 NC_013093.1 442348 443628 R PFAM: extracellular solute-binding protein family 1; KEGG: mlo:mll4149 sugar ABC transporter, (sugar- binding protein); family 1 extracellular solute-binding protein complement(442348..443628) Actinosynnema mirum DSM 43827 8324562 YP_003098217.1 CDS Amir_0404 NC_013093.1 443873 444622 D PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bcy:Bcer98_2752 GntR family transcriptional regulator; GntR family transcriptional regulator 443873..444622 Actinosynnema mirum DSM 43827 8324563 YP_003098218.1 CDS Amir_0405 NC_013093.1 444671 445618 R PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aba:Acid345_2084 pyridoxal-5'-phosphate- dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit complement(444671..445618) Actinosynnema mirum DSM 43827 8324564 YP_003098219.1 CDS Amir_0406 NC_013093.1 446394 447158 R PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: scl:sce0163 hypothetical protein; Extradiol ring-cleavage dioxygenase class III protein subunit B complement(446394..447158) Actinosynnema mirum DSM 43827 8324565 YP_003098220.1 CDS thiE NC_013093.1 447158 447916 R Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase complement(447158..447916) Actinosynnema mirum DSM 43827 8324566 YP_003098221.1 CDS Amir_0408 NC_013093.1 448503 449510 D TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: azc:AZC_3554 glycine oxidase precursor; glycine oxidase ThiO 448503..449510 Actinosynnema mirum DSM 43827 8324567 YP_003098222.1 CDS Amir_0409 NC_013093.1 449507 449704 D TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mms:mma_0316 thiamine biosynthesis protein ThiS; thiamine biosynthesis protein ThiS 449507..449704 Actinosynnema mirum DSM 43827 8324568 YP_003098223.1 CDS Amir_0410 NC_013093.1 449707 450495 D PFAM: thiazole biosynthesis family protein; KEGG: rce:RC1_3100 thiazole biosynthesis protein ThiG; thiazole biosynthesis family protein 449707..450495 Actinosynnema mirum DSM 43827 8324569 YP_003098224.1 CDS Amir_0411 NC_013093.1 450580 450999 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bcm:Bcenmc03_5734 MarR family transcriptional regulator; MarR family transcriptional regulator 450580..450999 Actinosynnema mirum DSM 43827 8324570 YP_003098225.1 CDS Amir_0412 NC_013093.1 451015 451833 R PFAM: O-methyltransferase; KEGG: mlo:mll3178 hypothetical protein; O-methyltransferase complement(451015..451833) Actinosynnema mirum DSM 43827 8324571 YP_003098226.1 CDS Amir_0413 NC_013093.1 451917 452123 R PFAM: protein of unknown function DUF397; hypothetical protein complement(451917..452123) Actinosynnema mirum DSM 43827 8324572 YP_003098227.1 CDS Amir_0414 NC_013093.1 452143 452997 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein complement(452143..452997) Actinosynnema mirum DSM 43827 8324573 YP_003098228.1 CDS Amir_0415 NC_013093.1 453216 453383 D KEGG: hypothetical protein; hypothetical protein 453216..453383 Actinosynnema mirum DSM 43827 8324574 YP_003098229.1 CDS Amir_0416 NC_013093.1 453387 453620 D hypothetical protein 453387..453620 Actinosynnema mirum DSM 43827 8324575 YP_003098230.1 CDS Amir_0417 NC_013093.1 453617 453964 D hypothetical protein 453617..453964 Actinosynnema mirum DSM 43827 8324576 YP_003098231.1 CDS Amir_0418 NC_013093.1 453918 454655 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bph:Bphy_4607 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(453918..454655) Actinosynnema mirum DSM 43827 8324577 YP_003098232.1 CDS Amir_0419 NC_013093.1 454677 455330 D PFAM: regulatory protein TetR; KEGG: bxe:Bxe_B1146 TetR family transcriptional regulator; TetR family transcriptional regulator 454677..455330 Actinosynnema mirum DSM 43827 8324578 YP_003098233.1 CDS Amir_0420 NC_013093.1 455336 456040 R KEGG: rec:RHECIAT_CH0002869 hydrolase protein; hydrolase protein complement(455336..456040) Actinosynnema mirum DSM 43827 8324579 YP_003098234.1 CDS Amir_0421 NC_013093.1 456177 456746 D PFAM: regulatory protein TetR; KEGG: smd:Smed_4442 transcriptional regulator, TetR family; TetR family transcriptional regulator 456177..456746 Actinosynnema mirum DSM 43827 8324580 YP_003098235.1 CDS Amir_0422 NC_013093.1 456953 457957 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: cak:Caul_0434 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(456953..457957) Actinosynnema mirum DSM 43827 8324581 YP_003098236.1 CDS Amir_0423 NC_013093.1 458084 458638 D PFAM: regulatory protein TetR; KEGG: cak:Caul_0435 TetR family transcriptional regulator; TetR family transcriptional regulator 458084..458638 Actinosynnema mirum DSM 43827 8324582 YP_003098237.1 CDS Amir_0424 NC_013093.1 458684 459514 R TIGRFAM: phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase type-1; KEGG: sfu:Sfum_1692 phosphomethylpyrimidine kinase; phosphomethylpyrimidine kinase complement(458684..459514) Actinosynnema mirum DSM 43827 8324583 YP_003098238.1 CDS Amir_0425 NC_013093.1 459516 461159 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(459516..461159) Actinosynnema mirum DSM 43827 8324584 YP_003098239.1 CDS Amir_0426 NC_013093.1 461485 462102 D hypothetical protein 461485..462102 Actinosynnema mirum DSM 43827 8324585 YP_003098240.1 CDS Amir_0427 NC_013093.1 462297 462884 R KEGG: pmr:PMI2825 peptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase; peptide deformylase complement(462297..462884) Actinosynnema mirum DSM 43827 8324586 YP_003098241.1 CDS Amir_0428 NC_013093.1 463048 463332 D hypothetical protein 463048..463332 Actinosynnema mirum DSM 43827 8324587 YP_003098242.1 CDS Amir_0429 NC_013093.1 463329 463991 D KEGG: hypothetical protein; hypothetical protein 463329..463991 Actinosynnema mirum DSM 43827 8324588 YP_003098243.1 CDS Amir_0430 NC_013093.1 464055 464762 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: mes:Meso_0568 transcriptional regulator, GntR family; GntR family transcriptional regulator complement(464055..464762) Actinosynnema mirum DSM 43827 8324589 YP_003098244.1 CDS Amir_0431 NC_013093.1 464849 465946 D PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: gme:Gmet_2577 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 464849..465946 Actinosynnema mirum DSM 43827 8324590 YP_003098245.1 CDS Amir_0432 NC_013093.1 466404 468608 D KEGG: mrd:Mrad2831_5798 AAA family ATPase, CDC48 subfamily protein; PFAM: ATPase AAA; SMART: ATPase AAA; Microtubule-severing ATPase 466404..468608 Actinosynnema mirum DSM 43827 8324591 YP_003098246.1 CDS Amir_0433 NC_013093.1 468892 469416 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: scl:sce7901 ECF family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 468892..469416 Actinosynnema mirum DSM 43827 8324592 YP_003098247.1 CDS Amir_0434 NC_013093.1 469413 470174 D KEGG: mxa:MXAN_3349 DnaJ domain protein; DnaJ domain-containing protein 469413..470174 Actinosynnema mirum DSM 43827 8324593 YP_003098248.1 CDS Amir_0435 NC_013093.1 470346 471323 R KEGG: mag:amb0603 phosphatidylserine synthase; TIGRFAM: CDP-diacylglycerol/serine O- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; CDP-diacylglycerol/serineO- phosphatidyltransferase complement(470346..471323) Actinosynnema mirum DSM 43827 8324594 YP_003098249.1 CDS Amir_0436 NC_013093.1 471327 472040 R KEGG: rce:RC1_1432 phosphatidylserine decarboxylase- like protein, TIGRFAM: phosphatidylserine decarboxylase related protein; PFAM: phosphatidylserine decarboxylase-related; phosphatidylserine decarboxylase-like protein complement(471327..472040) Actinosynnema mirum DSM 43827 8324595 YP_003098250.1 CDS Amir_0437 NC_013093.1 472257 473768 R PFAM: peptidase M48 Ste24p; KEGG: sfu:Sfum_1032 peptidase M48, Ste24p; peptidase M48 Ste24p complement(472257..473768) Actinosynnema mirum DSM 43827 8324596 YP_003098251.1 CDS Amir_0438 NC_013093.1 473915 475120 R TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: afw:Anae109_1445 molybdenum cofactor synthesis domain-containing protein; molybdenum cofactor synthesis domain-containing protein complement(473915..475120) Actinosynnema mirum DSM 43827 8324597 YP_003098252.1 CDS Amir_0439 NC_013093.1 475190 475798 D PFAM: protein of unknown function DUF124; KEGG: hypothetical protein; hypothetical protein 475190..475798 Actinosynnema mirum DSM 43827 8324598 YP_003098253.1 CDS Amir_0440 NC_013093.1 475930 476136 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ank:AnaeK_2630 cold-shock DNA-binding domain protein; cold-shock DNA-binding domain-containing protein 475930..476136 Actinosynnema mirum DSM 43827 8324599 YP_003098254.1 CDS Amir_0441 NC_013093.1 476271 477605 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; protein of unknown function RIO1; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: ade:Adeh_1074 serine/threonine protein kinase; serine/threonine protein kinase 476271..477605 Actinosynnema mirum DSM 43827 8324600 YP_003098255.1 CDS Amir_0442 NC_013093.1 477845 479467 D TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: bcb:BCB4264_A0298 chaperonin GroL; chaperonin GroEL 477845..479467 Actinosynnema mirum DSM 43827 8324601 YP_003098256.1 CDS Amir_0443 NC_013093.1 479947 480444 R hypothetical protein complement(479947..480444) Actinosynnema mirum DSM 43827 8324602 YP_003098257.1 CDS Amir_0444 NC_013093.1 480441 481046 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: sus:Acid_3132 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit complement(480441..481046) Actinosynnema mirum DSM 43827 8324603 YP_003098258.1 CDS Amir_0445 NC_013093.1 481427 482101 D PFAM: CutC family protein; KEGG: bcj:BCAL0655 CutC family protein; CutC family protein 481427..482101 Actinosynnema mirum DSM 43827 8324604 YP_003098259.1 CDS Amir_0446 NC_013093.1 482648 483922 D PFAM: extracellular solute-binding protein family 1; KEGG: rle:pRL100263 substrate-binding component of ABC transporter; family 1 extracellular solute-binding protein 482648..483922 Actinosynnema mirum DSM 43827 8324605 YP_003098260.1 CDS Amir_0447 NC_013093.1 483919 484830 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mxa:MXAN_7294 sugar ABC transporter, permease protein; sugar ABC transporter permease 483919..484830 Actinosynnema mirum DSM 43827 8324606 YP_003098261.1 CDS Amir_0448 NC_013093.1 484827 485660 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlt:Rleg2_3667 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 484827..485660 Actinosynnema mirum DSM 43827 8324607 YP_003098262.1 CDS Amir_0449 NC_013093.1 485657 487000 D PFAM: glycoside hydrolase, family 20, catalytic core; KEGG: nar:Saro_2417 beta-N-acetylhexosaminidase; beta-N-acetylhexosaminidase 485657..487000 Actinosynnema mirum DSM 43827 8324608 YP_003098263.1 CDS Amir_0450 NC_013093.1 487001 487255 R PFAM: PspC domain protein; KEGG: cbc:CbuK_0644 stress-responsive transcriptional regulator; phage shock protein PspC complement(487001..487255) Actinosynnema mirum DSM 43827 8324609 YP_003098264.1 CDS Amir_0451 NC_013093.1 487494 488600 D PFAM: protein of unknown function DUF182; KEGG: msl:Msil_0236 protein of unknown function DUF182; hypothetical protein 487494..488600 Actinosynnema mirum DSM 43827 8324610 YP_003098265.1 CDS Amir_0452 NC_013093.1 489427 490365 D catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 489427..490365 Actinosynnema mirum DSM 43827 8324611 YP_003098266.1 CDS Amir_0453 NC_013093.1 490565 492217 R PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: SSL2; DNA helicase; K10843 DNA excision repair protein ERCC-3; type III restriction protein res subunit complement(490565..492217) Actinosynnema mirum DSM 43827 8324612 YP_003098267.1 CDS Amir_0454 NC_013093.1 492343 492873 D hypothetical protein 492343..492873 Actinosynnema mirum DSM 43827 8324613 YP_003098268.1 CDS Amir_0455 NC_013093.1 492929 493387 D hypothetical protein 492929..493387 Actinosynnema mirum DSM 43827 8324614 YP_003098269.1 CDS Amir_0456 NC_013093.1 493478 494566 D KEGG: Prp2; proline rich protein 2; hypothetical protein 493478..494566 Actinosynnema mirum DSM 43827 8324615 YP_003098270.1 CDS Amir_0457 NC_013093.1 494631 495632 R KEGG: twin-arginine translocation pathway signal; K02051 sulfonate/nitrate/taurine transport system substrate-binding protein; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein complement(494631..495632) Actinosynnema mirum DSM 43827 8324616 YP_003098271.1 CDS Amir_0458 NC_013093.1 496042 499320 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; nitrate and nitrite sensing domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: mag:amb3383 methyl-accepting chemotaxis protein; sensor with HAMP domain 496042..499320 Actinosynnema mirum DSM 43827 8324617 YP_003098272.1 CDS Amir_0459 NC_013093.1 499317 499736 D PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_2813 roadblock/LC7 family protein; Roadblock/LC7 family protein 499317..499736 Actinosynnema mirum DSM 43827 8324618 YP_003098273.1 CDS Amir_0460 NC_013093.1 499962 500510 D PFAM: protein of unknown function DUF742; hypothetical protein 499962..500510 Actinosynnema mirum DSM 43827 8324619 YP_003098274.1 CDS Amir_0461 NC_013093.1 500491 501099 D PFAM: protein of unknown function ATP binding; KEGG: nmn:NMCC_1665 hypothetical protein; hypothetical protein 500491..501099 Actinosynnema mirum DSM 43827 8324620 YP_003098275.1 CDS Amir_0462 NC_013093.1 501188 502924 R KEGG: dac:Daci_2082 hypothetical protein; hypothetical protein complement(501188..502924) Actinosynnema mirum DSM 43827 8324621 YP_003098276.1 CDS Amir_0463 NC_013093.1 503041 505284 R KEGG: acp:A2cp1_2891 response regulator receiver; hypothetical protein complement(503041..505284) Actinosynnema mirum DSM 43827 8324622 YP_003098277.1 CDS Amir_0464 NC_013093.1 505350 505535 D hypothetical protein 505350..505535 Actinosynnema mirum DSM 43827 8324623 YP_003098278.1 CDS Amir_0465 NC_013093.1 505641 507044 D PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: sat:SYN_00517 NAD-dependent malic enzyme; malate dehydrogenase 505641..507044 Actinosynnema mirum DSM 43827 8324624 YP_003098279.1 CDS Amir_0466 NC_013093.1 507285 507758 D TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: eli:ELI_06520 molybdopterin cofactor biosynthesis MoaC region; molybdenum cofactor biosynthesis protein C 507285..507758 Actinosynnema mirum DSM 43827 8324625 YP_003098280.1 CDS Amir_0467 NC_013093.1 507755 508237 D TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: sfu:Sfum_0070 molybdenum cofactor synthesis domain; molybdenum cofactor synthesis domain-containing protein 507755..508237 Actinosynnema mirum DSM 43827 8324626 YP_003098281.1 CDS Amir_0468 NC_013093.1 508234 508659 D PFAM: molybdopterin biosynthesis MoaE protein; KEGG: scl:sce2941 molybdopterin-converting factor chain 2; molybdopterin biosynthesis MoaE protein 508234..508659 Actinosynnema mirum DSM 43827 8324627 YP_003098282.1 CDS Amir_0469 NC_013093.1 509101 509775 R PFAM: transglycosylase domain protein; SMART: peptidoglycan-binding LysM; KEGG: vei:Veis_4083 peptidoglycan-binding LysM; transglycosylase domain-containing protein complement(509101..509775) Actinosynnema mirum DSM 43827 8324628 YP_003098283.1 CDS Amir_0470 NC_013093.1 510138 510401 R PFAM: thiamineS protein; KEGG: ade:Adeh_1120 molybdopterin synthase subunit MoaE / molybdopterin synthase subunit MoaD; sulfur carrier protein ThiS complement(510138..510401) Actinosynnema mirum DSM 43827 8324629 YP_003098284.1 CDS moaA NC_013093.1 510403 511428 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(510403..511428) Actinosynnema mirum DSM 43827 8324630 YP_003098285.1 CDS Amir_0472 NC_013093.1 511563 512024 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bja:bll4976 transcriptional regulatory protein; MarR family transcriptional regulator 511563..512024 Actinosynnema mirum DSM 43827 8324631 YP_003098286.1 CDS Amir_0473 NC_013093.1 512044 512832 D TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: csa:Csal_0794 HAD-superfamily hydrolase, subfamily IIA; HAD superfamily hydrolase 512044..512832 Actinosynnema mirum DSM 43827 8324632 YP_003098287.1 CDS Amir_0474 NC_013093.1 512991 513695 D PFAM: protein of unknown function DUF1503; KEGG: scl:sce8705 hypothetical protein; hypothetical protein 512991..513695 Actinosynnema mirum DSM 43827 8324633 YP_003098288.1 CDS Amir_0475 NC_013093.1 514093 514917 D PFAM: metallophosphoesterase; KEGG: serine/threonine protein phosphatase; metallophosphoesterase 514093..514917 Actinosynnema mirum DSM 43827 8324634 YP_003098289.1 CDS Amir_0476 NC_013093.1 514951 515325 R PFAM: protein of unknown function DUF307; KEGG: rpa:RPA0774 hypothetical protein; hypothetical protein complement(514951..515325) Actinosynnema mirum DSM 43827 8324635 YP_003098290.1 CDS Amir_0477 NC_013093.1 515358 516356 D PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; oxidoreductase domain; KEGG: similar to dimeric dihydrodiol dehydrogenase; oxidoreductase domain-containing protein 515358..516356 Actinosynnema mirum DSM 43827 8324636 YP_003098291.1 CDS Amir_0478 NC_013093.1 516334 517299 R PFAM: regulatory protein TetR; KEGG: bbt:BBta_0237 OmpA family protein; TetR family transcriptional regulator complement(516334..517299) Actinosynnema mirum DSM 43827 8324637 YP_003098292.1 CDS Amir_0479 NC_013093.1 517475 518131 D PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: afw:Anae109_2037 HAD family hydrolase; Haloacid dehalogenase domain-containing protein hydrolase 517475..518131 Actinosynnema mirum DSM 43827 8324638 YP_003098293.1 CDS Amir_0480 NC_013093.1 518202 518405 R hypothetical protein complement(518202..518405) Actinosynnema mirum DSM 43827 8324639 YP_003098294.1 CDS Amir_0481 NC_013093.1 518534 518929 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: bcy:Bcer98_3497 cold-shock DNA-binding domain- containing protein; cold-shock DNA-binding domain-containing protein 518534..518929 Actinosynnema mirum DSM 43827 8324640 YP_003098295.1 CDS Amir_0482 NC_013093.1 519009 519494 R hypothetical protein complement(519009..519494) Actinosynnema mirum DSM 43827 8324641 YP_003098296.1 CDS Amir_0483 NC_013093.1 519518 521248 R PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_4876 major facilitator transporter; major facilitator superfamily protein complement(519518..521248) Actinosynnema mirum DSM 43827 8324642 YP_003098297.1 CDS Amir_0484 NC_013093.1 521305 522084 R PFAM: glutamine cyclotransferase; KEGG: sus:Acid_3566 glutamine cyclotransferase; glutamine cyclotransferase complement(521305..522084) Actinosynnema mirum DSM 43827 8324643 YP_003098298.1 CDS Amir_0485 NC_013093.1 522145 523071 D KEGG: GL17023 gene product from transcript GL17023- RA; hypothetical protein 522145..523071 Actinosynnema mirum DSM 43827 8324644 YP_003098299.1 CDS Amir_0486 NC_013093.1 523068 525896 D KEGG: nha:Nham_3709 hypothetical protein; hypothetical protein 523068..525896 Actinosynnema mirum DSM 43827 8324645 YP_003098300.1 CDS Amir_0487 NC_013093.1 526006 526251 R hypothetical protein complement(526006..526251) Actinosynnema mirum DSM 43827 8324646 YP_003098301.1 CDS Amir_0488 NC_013093.1 526391 527830 D PFAM: xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: acp:A2cp1_3490 xanthine/uracil/vitamin C permease; xanthine/uracil/vitamin C permease 526391..527830 Actinosynnema mirum DSM 43827 8324647 YP_003098302.1 CDS Amir_0489 NC_013093.1 527995 528441 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bvi:Bcep1808_5100 MarR family transcriptional regulator; MarR family transcriptional regulator 527995..528441 Actinosynnema mirum DSM 43827 8324648 YP_003098303.1 CDS Amir_0490 NC_013093.1 528446 529831 D PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: bpy:Bphyt_5813 major facilitator superfamily MFS_1; major facilitator superfamily protein 528446..529831 Actinosynnema mirum DSM 43827 8324649 YP_003098304.1 CDS Amir_0491 NC_013093.1 529828 531102 D PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: gdi:GDI0684 major facilitator transporter; major facilitator superfamily protein 529828..531102 Actinosynnema mirum DSM 43827 8324650 YP_003098305.1 CDS Amir_0492 NC_013093.1 531287 531916 R PFAM: manganese and iron superoxide dismutase; KEGG: hypothetical protein; superoxide dismutase complement(531287..531916) Actinosynnema mirum DSM 43827 8324651 YP_003098306.1 CDS Amir_0493 NC_013093.1 532020 533633 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6528 ABC transporter, ATP-binding protein; ABC transporter 532020..533633 Actinosynnema mirum DSM 43827 8324652 YP_003098307.1 CDS Amir_0494 NC_013093.1 533638 534048 D hypothetical protein 533638..534048 Actinosynnema mirum DSM 43827 8324653 YP_003098308.1 CDS Amir_0495 NC_013093.1 534080 535573 R PFAM: glutamate--cysteine ligase GCS2; KEGG: scl:sce0051 hypothetical protein; glutamate--cysteine ligase GCS2 complement(534080..535573) Actinosynnema mirum DSM 43827 8324654 YP_003098309.1 CDS Amir_0496 NC_013093.1 535700 536551 D PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mes:Meso_2208 tRNA/rRNA methyltransferase (SpoU); tRNA/rRNA methyltransferase SpoU 535700..536551 Actinosynnema mirum DSM 43827 8324655 YP_003098310.1 CDS Amir_0497 NC_013093.1 536593 537243 D KEGG: hypothetical protein; hypothetical protein 536593..537243 Actinosynnema mirum DSM 43827 8324656 YP_003098311.1 CDS Amir_0498 NC_013093.1 537256 538983 D PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; dienelactone hydrolase; phospholipase/carboxylesterase; KEGG: hypothetical protein; peptidase S9 prolyl oligopeptidase active site domain-containing protein 537256..538983 Actinosynnema mirum DSM 43827 8324657 YP_003098312.1 CDS Amir_0499 NC_013093.1 539369 540679 R PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: lpp:lpp1608 hypothetical protein; major facilitator superfamily protein complement(539369..540679) Actinosynnema mirum DSM 43827 8324658 YP_003098313.1 CDS Amir_0500 NC_013093.1 540751 542352 D PFAM: polysaccharide lyase family 8; polysaccharide lyase 8 alpha-helical; KEGG: vvy:VVA1636 hypothetical protein; polysaccharide lyase family 8 540751..542352 Actinosynnema mirum DSM 43827 8324659 YP_003098314.1 CDS Amir_0501 NC_013093.1 542596 543255 R KEGG: rpi:Rpic_0717 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase complement(542596..543255) Actinosynnema mirum DSM 43827 8324660 YP_003098315.1 CDS Amir_0502 NC_013093.1 543312 544157 R KEGG: scl:sce6547 urease accessory protein UreD; urease accessory protein UreD complement(543312..544157) Actinosynnema mirum DSM 43827 8324661 YP_003098316.1 CDS Amir_0503 NC_013093.1 544235 544771 D hypothetical protein 544235..544771 Actinosynnema mirum DSM 43827 8324662 YP_003098317.1 CDS Amir_0504 NC_013093.1 544741 545454 R TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: scl:sce6551 urease accessory protein G; urease accessory protein UreG complement(544741..545454) Actinosynnema mirum DSM 43827 8324663 YP_003098318.1 CDS Amir_0505 NC_013093.1 545444 546106 R KEGG: ank:AnaeK_0974 hypothetical protein; hypothetical protein complement(545444..546106) Actinosynnema mirum DSM 43827 8324664 YP_003098319.1 CDS ureC NC_013093.1 546215 547912 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(546215..547912) Actinosynnema mirum DSM 43827 8324665 YP_003098320.1 CDS Amir_0507 NC_013093.1 547909 548220 R KEGG: atu:Atu2405 urease subunit beta; TIGRFAM: urease subunit beta; PFAM: Urease beta subunit; urease subunit beta complement(547909..548220) Actinosynnema mirum DSM 43827 8324666 YP_003098321.1 CDS Amir_0508 NC_013093.1 548279 548581 R KEGG: oan:Oant_0332 urease subunit gamma; TIGRFAM: urease subunit gamma; PFAM: Urease gamma subunit region; urease subunit gamma complement(548279..548581) Actinosynnema mirum DSM 43827 8324667 YP_003098322.1 CDS Amir_0509 NC_013093.1 548814 549929 D forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; citrate synthase 2 548814..549929 Actinosynnema mirum DSM 43827 8324668 YP_003098323.1 CDS Amir_0510 NC_013093.1 550082 550912 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sus:Acid_0079 ABC transporter; ABC transporter 550082..550912 Actinosynnema mirum DSM 43827 8324669 YP_003098324.1 CDS Amir_0511 NC_013093.1 550909 551709 D PFAM: ABC transporter; KEGG: mxa:MXAN_1598 ABC transporter, permease protein, ABC-2 family; ABC transporter 550909..551709 Actinosynnema mirum DSM 43827 8324670 YP_003098325.1 CDS Amir_0512 NC_013093.1 551682 552701 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sus:Acid_1273 integral membrane sensor signal transduction histidine kinase; histidine kinase 551682..552701 Actinosynnema mirum DSM 43827 8324671 YP_003098326.1 CDS Amir_0513 NC_013093.1 552766 553395 D PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: sus:Acid_2683 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 552766..553395 Actinosynnema mirum DSM 43827 8324672 YP_003098327.1 CDS Amir_0514 NC_013093.1 553647 554780 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 553647..554780 Actinosynnema mirum DSM 43827 8324673 YP_003098328.1 CDS Amir_0515 NC_013093.1 555000 555815 D hypothetical protein 555000..555815 Actinosynnema mirum DSM 43827 8324674 YP_003098329.1 CDS Amir_0516 NC_013093.1 556396 556770 D hypothetical protein 556396..556770 Actinosynnema mirum DSM 43827 8324675 YP_003098330.1 CDS Amir_0517 NC_013093.1 556763 557443 D KEGG: similar to hedgehog protein; hypothetical protein 556763..557443 Actinosynnema mirum DSM 43827 8324676 YP_003098331.1 CDS Amir_0518 NC_013093.1 557503 557742 R hypothetical protein complement(557503..557742) Actinosynnema mirum DSM 43827 8324677 YP_003098332.1 CDS Amir_0519 NC_013093.1 557855 559624 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rce:RC1_1837 ABC transporter, ATP-binding; ABC transporter 557855..559624 Actinosynnema mirum DSM 43827 8324678 YP_003098333.1 CDS Amir_0520 NC_013093.1 559621 561579 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: bha:BH1126 ABC transporter ATP-binding protein; ABC transporter 559621..561579 Actinosynnema mirum DSM 43827 8324679 YP_003098334.1 CDS Amir_0521 NC_013093.1 562328 562894 D PFAM: regulatory protein TetR; KEGG: gdj:Gdia_1592 regulatory protein TetR; TetR family transcriptional regulator 562328..562894 Actinosynnema mirum DSM 43827 8324680 YP_003098335.1 CDS Amir_0522 NC_013093.1 563263 564681 D PFAM: amino acid permease-associated region; KEGG: bpt:Bpet1644 amino acid transporter; amino acid permease-associated protein 563263..564681 Actinosynnema mirum DSM 43827 8324681 YP_003098336.1 CDS Amir_0523 NC_013093.1 564778 565650 D PFAM: Aldose 1-epimerase; KEGG: sfv:SFV_3620 aldose-1-epimerase; Aldose 1-epimerase 564778..565650 Actinosynnema mirum DSM 43827 8324682 YP_003098337.1 CDS Amir_0524 NC_013093.1 565670 566863 D PFAM: amidohydrolase; Amidohydrolase 3; KEGG: bha:BH3008 hypothetical protein; amidohydrolase 565670..566863 Actinosynnema mirum DSM 43827 8324683 YP_003098338.1 CDS Amir_0525 NC_013093.1 566946 568091 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bat:BAS5190 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein complement(566946..568091) Actinosynnema mirum DSM 43827 8324684 YP_003098339.1 CDS Amir_0526 NC_013093.1 568174 568770 D PFAM: regulatory protein TetR; KEGG: rme:Rmet_3794 transcriptional regulator, TetR family; TetR family transcriptional regulator 568174..568770 Actinosynnema mirum DSM 43827 8324685 YP_003098340.1 CDS Amir_0527 NC_013093.1 568767 569705 D PFAM: PfkB domain protein; KEGG: sit:TM1040_3042 PfkB; PfkB domain-containing protein 568767..569705 Actinosynnema mirum DSM 43827 8324686 YP_003098341.1 CDS Amir_0528 NC_013093.1 569976 571289 D KEGG: scl:sce8281 hypothetical protein; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; citrate synthase I 569976..571289 Actinosynnema mirum DSM 43827 8324687 YP_003098342.1 CDS Amir_0529 NC_013093.1 571555 572820 D PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: cvi:CV_3481 deoxyribodipyrimidine photo-lyase; deoxyribodipyrimidine photo-lyase 571555..572820 Actinosynnema mirum DSM 43827 8324688 YP_003098343.1 CDS Amir_0530 NC_013093.1 572906 573550 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: tgr:Tgr7_2171 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator complement(572906..573550) Actinosynnema mirum DSM 43827 8324689 YP_003098344.1 CDS Amir_0531 NC_013093.1 573565 574854 R PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: mmr:Mmar10_2544 signal transduction histidine kinase; histidine kinase complement(573565..574854) Actinosynnema mirum DSM 43827 8324690 YP_003098345.1 CDS Amir_0532 NC_013093.1 575005 576246 R KEGG: scl:sce9075 hypothetical protein; sodium ABC transporter permease complement(575005..576246) Actinosynnema mirum DSM 43827 8324691 YP_003098346.1 CDS Amir_0533 NC_013093.1 576243 577196 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH1166 ABC transporter ATP-binding protein; ABC transporter complement(576243..577196) Actinosynnema mirum DSM 43827 8324692 YP_003098347.1 CDS Amir_0534 NC_013093.1 577222 577482 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: gdi:GDI1973 HTH-type transcriptional regulator; XRE family transcriptional regulator complement(577222..577482) Actinosynnema mirum DSM 43827 8324693 YP_003098348.1 CDS Amir_0535 NC_013093.1 577666 578109 D PFAM: conserved hypothetical protein; KEGG: lpn:lpg2755 hypothetical protein; hypothetical protein 577666..578109 Actinosynnema mirum DSM 43827 8324694 YP_003098349.1 CDS Amir_0536 NC_013093.1 578130 578438 D hypothetical protein 578130..578438 Actinosynnema mirum DSM 43827 8324695 YP_003098350.1 CDS Amir_0537 NC_013093.1 578435 580219 D KEGG: predicted gene, 100041170; hypothetical protein 578435..580219 Actinosynnema mirum DSM 43827 8324696 YP_003098351.1 CDS Amir_0538 NC_013093.1 580973 582172 D PFAM: Amidohydrolase 3; KEGG: bac:BamMC406_5450 N-isopropylammelide isopropylaminohydrolase; N-isopropylammelide isopropylaminohydrolase 580973..582172 Actinosynnema mirum DSM 43827 8324697 YP_003098352.1 CDS Amir_0539 NC_013093.1 582162 583166 R PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pzu:PHZ_c1983 alcohol dehydrogenase, zinc- containing; alcohol dehydrogenase zinc-binding domain-containing protein complement(582162..583166) Actinosynnema mirum DSM 43827 8324698 YP_003098353.1 CDS Amir_0540 NC_013093.1 583222 583977 R PFAM: GCN5-related N-acetyltransferase; KEGG: bur:Bcep18194_A4874 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(583222..583977) Actinosynnema mirum DSM 43827 8324699 YP_003098354.1 CDS Amir_0541 NC_013093.1 584070 584606 R KEGG: tgr:Tgr7_2517 hypothetical protein; hypothetical protein complement(584070..584606) Actinosynnema mirum DSM 43827 8324700 YP_003098355.1 CDS Amir_0542 NC_013093.1 584603 587401 R PFAM: cell divisionFtsK/SpoIIIE; KEGG: bpt:Bpet4245 hypothetical protein; cell division protein FtsK/SpoIIIE complement(584603..587401) Actinosynnema mirum DSM 43827 8324701 YP_003098356.1 CDS Amir_0543 NC_013093.1 587403 587654 R hypothetical protein complement(587403..587654) Actinosynnema mirum DSM 43827 8324702 YP_003098357.1 CDS Amir_0544 NC_013093.1 587651 587911 R hypothetical protein complement(587651..587911) Actinosynnema mirum DSM 43827 8324703 YP_003098358.1 CDS Amir_0545 NC_013093.1 588061 589773 R KEGG: hypothetical protein; hypothetical protein complement(588061..589773) Actinosynnema mirum DSM 43827 8324704 YP_003098359.1 CDS Amir_0546 NC_013093.1 590316 590795 D hypothetical protein 590316..590795 Actinosynnema mirum DSM 43827 8324705 YP_003098360.1 CDS Amir_0547 NC_013093.1 590868 591659 R PFAM: alpha/beta hydrolase fold; KEGG: spe:Spro_0615 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein complement(590868..591659) Actinosynnema mirum DSM 43827 8324706 YP_003098361.1 CDS Amir_0548 NC_013093.1 591709 592527 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: dvm:DvMF_0511 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(591709..592527) Actinosynnema mirum DSM 43827 8324707 YP_003098362.1 CDS Amir_0549 NC_013093.1 592602 593429 D TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: phenazine biosynthesis PhzC/PhzF protein; KEGG: aha:AHA_2368 phenazine biosynthesis protein PhzF; phenazine biosynthesis protein PhzF family 592602..593429 Actinosynnema mirum DSM 43827 8324708 YP_003098363.1 CDS Amir_0550 NC_013093.1 593919 594908 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bcm:Bcenmc03_5299 LysR family transcriptional regulator; LysR family transcriptional regulator 593919..594908 Actinosynnema mirum DSM 43827 8324709 YP_003098364.1 CDS Amir_0551 NC_013093.1 594981 595796 R PFAM: NmrA family protein; short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_5100 NmrA family protein; NmrA family protein complement(594981..595796) Actinosynnema mirum DSM 43827 8324710 YP_003098365.1 CDS Amir_0552 NC_013093.1 595883 596269 D PFAM: helix-turn-helix HxlR type; KEGG: mxa:MXAN_5099 transcriptional regulator; HxlR family transcriptional regulator 595883..596269 Actinosynnema mirum DSM 43827 8324711 YP_003098366.1 CDS Amir_0553 NC_013093.1 596361 597458 D PFAM: AIG2 family protein; KEGG: pae:PA4164 hypothetical protein; AIG2 family protein 596361..597458 Actinosynnema mirum DSM 43827 8324712 YP_003098367.1 CDS Amir_0554 NC_013093.1 597634 598308 D KEGG: rpc:RPC_3182 peptidase C14, caspase catalytic subunit P20; peptidase C14, caspase catalytic subunit P20 597634..598308 Actinosynnema mirum DSM 43827 8324713 YP_003098368.1 CDS Amir_0555 NC_013093.1 598611 600047 R KEGG: hha:Hhal_1735 ABC transporter; hypothetical protein complement(598611..600047) Actinosynnema mirum DSM 43827 8324714 YP_003098369.1 CDS Amir_0556 NC_013093.1 600103 601911 R PFAM: GTP-binding protein HSR1-related; KEGG: scl:sce0387 hypothetical protein; HSR1-like GTP-binding protein complement(600103..601911) Actinosynnema mirum DSM 43827 8324715 YP_003098370.1 CDS Amir_0557 NC_013093.1 602010 602867 R KEGG: bcj:BCAS0321a hypothetical protein; hypothetical protein complement(602010..602867) Actinosynnema mirum DSM 43827 8324716 YP_003098371.1 CDS Amir_0558 NC_013093.1 603113 604432 D KEGG: hha:Hhal_0145 heat shock protein 70; molecular chaperone-like protein 603113..604432 Actinosynnema mirum DSM 43827 8324717 YP_003098372.1 CDS Amir_0559 NC_013093.1 604441 606807 D PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_3854 tetratricopeptide TPR_2 repeat protein; LuxR family transcriptional regulator 604441..606807 Actinosynnema mirum DSM 43827 8324718 YP_003098373.1 CDS Amir_0560 NC_013093.1 607000 607530 R KEGG: hch:HCH_05440 small integral membrane protein; small integral membrane protein complement(607000..607530) Actinosynnema mirum DSM 43827 8324719 YP_003098374.1 CDS Amir_0561 NC_013093.1 607655 611689 R PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce4551 protein kinase; hypothetical protein complement(607655..611689) Actinosynnema mirum DSM 43827 8324720 YP_003098375.1 CDS Amir_0562 NC_013093.1 612309 612665 R KEGG: similar to zinc finger protein 607; hypothetical protein complement(612309..612665) Actinosynnema mirum DSM 43827 8324721 YP_003098376.1 CDS Amir_0563 NC_013093.1 612716 614470 D PFAM: AlkA domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6205 regulatory protein Ada; AraC family transcriptional regulator 612716..614470 Actinosynnema mirum DSM 43827 8324722 YP_003098377.1 CDS Amir_0564 NC_013093.1 614627 614773 D hypothetical protein 614627..614773 Actinosynnema mirum DSM 43827 8324723 YP_003098378.1 CDS Amir_0565 NC_013093.1 614904 615737 R PFAM: protein of unknown function DUF574; KEGG: scl:sce6070 hypothetical protein; hypothetical protein complement(614904..615737) Actinosynnema mirum DSM 43827 8324724 YP_003098379.1 CDS Amir_0566 NC_013093.1 615946 616830 D hypothetical protein 615946..616830 Actinosynnema mirum DSM 43827 8324725 YP_003098380.1 CDS Amir_0567 NC_013093.1 616934 617221 D PFAM: protein of unknown function DUF397; hypothetical protein 616934..617221 Actinosynnema mirum DSM 43827 8324726 YP_003098381.1 CDS Amir_0568 NC_013093.1 617205 617510 D hypothetical protein 617205..617510 Actinosynnema mirum DSM 43827 8324727 YP_003098382.1 CDS Amir_0569 NC_013093.1 617909 619162 R KEGG: hypothetical LOC586091; membrane-bound lytic murein transglycosylase B-like protein complement(617909..619162) Actinosynnema mirum DSM 43827 8324728 YP_003098383.1 CDS Amir_0570 NC_013093.1 619562 625705 D TIGRFAM: hypothetical protein; LPXTG- motif cell wall anchor domain protein; PFAM: Cna B domain protein; Pericardin like; KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein 619562..625705 Actinosynnema mirum DSM 43827 8324729 YP_003098384.1 CDS Amir_0572 NC_013093.1 626473 631002 D TIGRFAM: YD repeat protein; KEGG: rso:RS05482 rhs-related transmembrane protein; YD repeat-containing protein 626473..631002 Actinosynnema mirum DSM 43827 8324731 YP_003098385.1 CDS Amir_0573 NC_013093.1 631013 631729 D hypothetical protein 631013..631729 Actinosynnema mirum DSM 43827 8324732 YP_003098386.1 CDS Amir_0574 NC_013093.1 631738 632154 D hypothetical protein 631738..632154 Actinosynnema mirum DSM 43827 8324733 YP_003098387.1 CDS Amir_0575 NC_013093.1 632186 632659 R PFAM: NUDIX hydrolase; KEGG: bbt:BBta_3942 NUDIX-like hydrolase; NUDIX hydrolase complement(632186..632659) Actinosynnema mirum DSM 43827 8324734 YP_003098388.1 CDS Amir_0576 NC_013093.1 633802 636642 D PFAM: transcriptional activator domain; hypothetical protein; hypothetical protein; NB- ARC domain protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator 633802..636642 Actinosynnema mirum DSM 43827 8324735 YP_003098389.1 CDS Amir_0577 NC_013093.1 636814 637278 D KEGG: xcv:XCV0585 hypothetical protein; hypothetical protein 636814..637278 Actinosynnema mirum DSM 43827 8324736 YP_003098390.1 CDS Amir_0578 NC_013093.1 637607 637975 D hypothetical protein 637607..637975 Actinosynnema mirum DSM 43827 8324737 YP_003098391.1 CDS Amir_0579 NC_013093.1 637962 638327 D hypothetical protein 637962..638327 Actinosynnema mirum DSM 43827 8324738 YP_003098392.1 CDS Amir_0580 NC_013093.1 638324 639445 D KEGG: hypothetical protein; hypothetical protein 638324..639445 Actinosynnema mirum DSM 43827 8324739 YP_003098393.1 CDS Amir_0581 NC_013093.1 640633 641100 D KEGG: pca:Pcar_0786 hypothetical protein; hypothetical protein 640633..641100 Actinosynnema mirum DSM 43827 8324740 YP_003098394.1 CDS Amir_0583 NC_013093.1 641901 642743 D PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 641901..642743 Actinosynnema mirum DSM 43827 8324742 YP_003098395.1 CDS Amir_0584 NC_013093.1 642722 642826 R hypothetical protein complement(642722..642826) Actinosynnema mirum DSM 43827 8324743 YP_003098396.1 CDS Amir_0585 NC_013093.1 642843 643604 R PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein complement(642843..643604) Actinosynnema mirum DSM 43827 8324744 YP_003098397.1 CDS Amir_0586 NC_013093.1 643644 644723 R hypothetical protein complement(643644..644723) Actinosynnema mirum DSM 43827 8324745 YP_003098398.1 CDS Amir_0588 NC_013093.1 645528 646220 D KEGG: ppr:PBPRA2228 carboxynorspermidine decarboxylase; hypothetical protein 645528..646220 Actinosynnema mirum DSM 43827 8324747 YP_003098399.1 CDS Amir_0589 NC_013093.1 646222 648237 D hypothetical protein 646222..648237 Actinosynnema mirum DSM 43827 8324748 YP_003098400.1 CDS Amir_0590 NC_013093.1 648541 649371 R PFAM: phosphoadenosine phosphosulfate reductase; KEGG: swi:Swit_5329 phosphoadenosine phosphosulfate reductase; phosphoadenosine phosphosulfate reductase complement(648541..649371) Actinosynnema mirum DSM 43827 8324749 YP_003098401.1 CDS Amir_0591 NC_013093.1 649368 652946 R KEGG: swi:Swit_5328 hypothetical protein; hypothetical protein complement(649368..652946) Actinosynnema mirum DSM 43827 8324750 YP_003098402.1 CDS Amir_0592 NC_013093.1 652943 654061 R KEGG: swi:Swit_5327 hypothetical protein; hypothetical protein complement(652943..654061) Actinosynnema mirum DSM 43827 8324751 YP_003098403.1 CDS Amir_0593 NC_013093.1 654119 655288 R PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: afw:Anae109_1098 aminotransferase class V; class V aminotransferase complement(654119..655288) Actinosynnema mirum DSM 43827 8324752 YP_003098404.1 CDS Amir_0594 NC_013093.1 655826 657403 D PFAM: type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: nha:Nham_3708 helicase-like; type III restriction protein res subunit 655826..657403 Actinosynnema mirum DSM 43827 8324753 YP_003098405.1 CDS Amir_0595 NC_013093.1 657388 659277 D KEGG: rpe:RPE_2170 hypothetical protein; hypothetical protein 657388..659277 Actinosynnema mirum DSM 43827 8324754 YP_003098406.1 CDS Amir_0596 NC_013093.1 659274 660161 D KEGG: bbr:BB2173 bifunctional riboflavin kinase/FMN adenylyltransferase; hypothetical protein 659274..660161 Actinosynnema mirum DSM 43827 8324755 YP_003098407.1 CDS Amir_0598 NC_013093.1 661424 662275 D PFAM: integrase family protein; KEGG: cjd:JJD26997_0344 phage integrase; integrase family protein 661424..662275 Actinosynnema mirum DSM 43827 8324757 YP_003098408.1 CDS Amir_0599 NC_013093.1 662795 663703 D hypothetical protein 662795..663703 Actinosynnema mirum DSM 43827 8324759 YP_003098409.1 CDS Amir_0600 NC_013093.1 663901 666813 R PFAM: peptidase S45 penicillin amidase; KEGG: abc:ACICU_01963 protein related to penicillin acylase; Penicillin amidase complement(663901..666813) Actinosynnema mirum DSM 43827 8324760 YP_003098410.1 CDS Amir_0601 NC_013093.1 667159 667806 D PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 667159..667806 Actinosynnema mirum DSM 43827 8324761 YP_003098411.1 CDS Amir_0602 NC_013093.1 667782 669695 R KEGG: mgm:Mmc1_3430 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase complement(667782..669695) Actinosynnema mirum DSM 43827 8324762 YP_003098412.1 CDS Amir_0603 NC_013093.1 669772 670404 R TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; KEGG: ajs:Ajs_3177 cob(II)yrinic acid a,c-diamide reductase; cob(II)yrinic acid a,c-diamide reductase complement(669772..670404) Actinosynnema mirum DSM 43827 8324763 YP_003098413.1 CDS Amir_0604 NC_013093.1 670501 670734 R TIGRFAM: ribosomal protein S18; PFAM: ribosomal protein S18; KEGG: bha:BH4048 30S ribosomal protein S18; 30S ribosomal protein S18 complement(670501..670734) Actinosynnema mirum DSM 43827 8324764 YP_003098414.1 CDS Amir_0605 NC_013093.1 670746 671042 R PFAM: ribosomal protein S14; KEGG: ilo:IL1903 ribosomal protein S14; 30S ribosomal protein S14 complement(670746..671042) Actinosynnema mirum DSM 43827 8324765 YP_003098415.1 CDS Amir_0606 NC_013093.1 671044 671211 R TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: bpe:BP2050 50S ribosomal protein L33; 50S ribosomal protein L33 complement(671044..671211) Actinosynnema mirum DSM 43827 8324766 YP_003098416.1 CDS Amir_0607 NC_013093.1 671211 671450 R TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: tcx:Tcr_1918 ribosomal protein L28; 50S ribosomal protein L28 complement(671211..671450) Actinosynnema mirum DSM 43827 8324767 YP_003098417.1 CDS Amir_0608 NC_013093.1 671544 672197 R PFAM: phosphoglycerate mutase; KEGG: phosphoglycerate/bisphosphoglycerate mutase family protein; phosphoglycerate mutase complement(671544..672197) Actinosynnema mirum DSM 43827 8324768 YP_003098418.1 CDS Amir_0609 NC_013093.1 672244 672594 D PFAM: ethyl tert-butyl ether degradation EthD; KEGG: bha:BH0200 hypothetical protein; ethyl tert-butyl ether degradation protein EthD 672244..672594 Actinosynnema mirum DSM 43827 8324769 YP_003098419.1 CDS Amir_0610 NC_013093.1 672591 673421 D PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: scl:sce7905 hypothetical protein; 3-hydroxyacyl-CoA dehydrogenase 672591..673421 Actinosynnema mirum DSM 43827 8324770 YP_003098420.1 CDS Amir_0611 NC_013093.1 673500 674636 D PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_5851 acetyltransferase, GNAT family; GCN5-like N-acetyltransferase 673500..674636 Actinosynnema mirum DSM 43827 8324771 YP_003098421.1 CDS Amir_0612 NC_013093.1 674727 675413 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfu:Sfum_2007 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 674727..675413 Actinosynnema mirum DSM 43827 8324772 YP_003098422.1 CDS Amir_0613 NC_013093.1 675410 676840 D PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sfu:Sfum_2006 integral membrane sensor signal transduction histidine kinase; histidine kinase 675410..676840 Actinosynnema mirum DSM 43827 8324773 YP_003098423.1 CDS Amir_0614 NC_013093.1 676917 677777 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_2010 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein complement(676917..677777) Actinosynnema mirum DSM 43827 8324774 YP_003098424.1 CDS Amir_0615 NC_013093.1 677774 678682 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL120384 permease component of ABC transporter; ABC transporter inner membrane protein complement(677774..678682) Actinosynnema mirum DSM 43827 8324775 YP_003098425.1 CDS Amir_0616 NC_013093.1 678688 679986 R PFAM: extracellular solute-binding protein family 1; KEGG: sugar ABC transporter; family 1 extracellular solute-binding protein complement(678688..679986) Actinosynnema mirum DSM 43827 8324776 YP_003098426.1 CDS Amir_0617 NC_013093.1 680221 682254 D PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; beta-galactosidase domain protein; KEGG: bha:BH3701 beta-galactosidase; beta-galactosidase 680221..682254 Actinosynnema mirum DSM 43827 8324777 YP_003098427.1 CDS Amir_0618 NC_013093.1 682257 683057 D PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: glpRb; glycerol-3-phosphate transcriptional regulator protein; DeoR family transcriptional regulator 682257..683057 Actinosynnema mirum DSM 43827 8324778 YP_003098428.1 CDS Amir_0619 NC_013093.1 683054 684148 D KEGG: nmu:Nmul_A1939 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; galactose-1-phosphate uridylyltransferase 683054..684148 Actinosynnema mirum DSM 43827 8324779 YP_003098429.1 CDS Amir_0620 NC_013093.1 684324 686348 D PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; KEGG: gox:GOX0798 serine protease; peptidase S1 and S6 chymotrypsin/Hap 684324..686348 Actinosynnema mirum DSM 43827 8324780 YP_003098430.1 CDS Amir_0621 NC_013093.1 686531 686635 R hypothetical protein complement(686531..686635) Actinosynnema mirum DSM 43827 8324781 YP_003098431.1 CDS Amir_0622 NC_013093.1 686868 687368 D TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: sfu:Sfum_0070 molybdenum cofactor synthesis domain; molybdenum cofactor synthesis domain-containing protein 686868..687368 Actinosynnema mirum DSM 43827 8324782 YP_003098432.1 CDS Amir_0623 NC_013093.1 687365 687535 D hypothetical protein 687365..687535 Actinosynnema mirum DSM 43827 8324783 YP_003098433.1 CDS Amir_0624 NC_013093.1 688177 688707 R TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; KEGG: spe:Spro_4515 large-conductance mechanosensitive channel; large conductance mechanosensitive channel protein complement(688177..688707) Actinosynnema mirum DSM 43827 8324784 YP_003098434.1 CDS Amir_0625 NC_013093.1 689131 689706 R PFAM: SAF domain protein; KEGG: dvm:DvMF_2742 Flp pilus assembly protein CpaB; SAF domain-containing protein complement(689131..689706) Actinosynnema mirum DSM 43827 8324785 YP_003098435.1 CDS Amir_0626 NC_013093.1 689796 690101 R TIGRFAM: regulatory protein, FmdB family; KEGG: scl:sce1745 hypothetical protein; FmdB family regulatory protein complement(689796..690101) Actinosynnema mirum DSM 43827 8324786 YP_003098436.1 CDS Amir_0627 NC_013093.1 690203 690769 R TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: ade:Adeh_1046 5-formyltetrahydrofolate cyclo- ligase; 5-formyltetrahydrofolate cyclo-ligase complement(690203..690769) Actinosynnema mirum DSM 43827 8324787 YP_003098437.1 CDS Amir_0628 NC_013093.1 690808 691689 D PFAM: Nucleotidyl transferase; KEGG: mag:amb4451 UDP-glucose pyrophosphorylase; Nucleotidyl transferase 690808..691689 Actinosynnema mirum DSM 43827 8324788 YP_003098438.1 CDS Amir_0629 NC_013093.1 691722 692945 D TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: hha:Hhal_0242 molybdenum cofactor synthesis domain; molybdenum cofactor synthesis domain-containing protein 691722..692945 Actinosynnema mirum DSM 43827 8324789 YP_003098439.1 CDS Amir_0630 NC_013093.1 692949 693608 D PFAM: GCN5-related N-acetyltransferase; KEGG: smd:Smed_0534 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 692949..693608 Actinosynnema mirum DSM 43827 8324790 YP_003098440.1 CDS Amir_0631 NC_013093.1 693762 694406 D hypothetical protein 693762..694406 Actinosynnema mirum DSM 43827 8324791 YP_003098441.1 CDS Amir_0632 NC_013093.1 694897 695607 D PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: nwi:Nwi_3032 Crp family transcriptional regulator; Crp/Fnr family transcriptional regulator 694897..695607 Actinosynnema mirum DSM 43827 8324793 YP_003098442.1 CDS Amir_0633 NC_013093.1 695634 696263 D hypothetical protein 695634..696263 Actinosynnema mirum DSM 43827 8324794 YP_003098443.1 CDS Amir_0634 NC_013093.1 696274 699279 D PFAM: UvrD/REP helicase; KEGG: scl:sce3530 ATP-dependent DNA helicase; UvrD/REP helicase 696274..699279 Actinosynnema mirum DSM 43827 8324795 YP_003098444.1 CDS Amir_0635 NC_013093.1 699424 701589 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_4017 serine/threonine protein kinase; serine/threonine protein kinase 699424..701589 Actinosynnema mirum DSM 43827 8324796 YP_003098445.1 CDS Amir_0636 NC_013093.1 701659 703230 R PFAM: glycosyl transferase family 39; KEGG: glycosyl transferase family 39; glycosyl transferase family protein complement(701659..703230) Actinosynnema mirum DSM 43827 8324797 YP_003098446.1 CDS Amir_0637 NC_013093.1 703255 704100 D PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tgr:Tgr7_0758 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase 703255..704100 Actinosynnema mirum DSM 43827 8324798 YP_003098447.1 CDS Amir_0638 NC_013093.1 704087 704491 R hypothetical protein complement(704087..704491) Actinosynnema mirum DSM 43827 8324799 YP_003098448.1 CDS Amir_0639 NC_013093.1 704551 705114 R hypothetical protein complement(704551..705114) Actinosynnema mirum DSM 43827 8324800 YP_003098449.1 CDS Amir_0640 NC_013093.1 705189 705563 R hypothetical protein complement(705189..705563) Actinosynnema mirum DSM 43827 8324801 YP_003098450.1 CDS Amir_0641 NC_013093.1 705567 706187 R hypothetical protein complement(705567..706187) Actinosynnema mirum DSM 43827 8324802 YP_003098451.1 CDS Amir_0642 NC_013093.1 706283 708073 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 706283..708073 Actinosynnema mirum DSM 43827 8324803 YP_003098452.1 CDS Amir_0643 NC_013093.1 708124 708894 D TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: bcz:BCZK0035 TatD related DNase; hydrolase, TatD family 708124..708894 Actinosynnema mirum DSM 43827 8324804 YP_003098453.1 CDS Amir_0644 NC_013093.1 709193 710614 D PFAM: transglycosylase domain protein; protein of unknown function DUF348; G5 domain protein; KEGG: bsu:BSU00400 hypothetical protein; transglycosylase domain-containing protein 709193..710614 Actinosynnema mirum DSM 43827 8324805 YP_003098454.1 CDS ksgA NC_013093.1 710778 711674 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 710778..711674 Actinosynnema mirum DSM 43827 8324806 YP_003098455.1 CDS Amir_0646 NC_013093.1 712071 713072 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: rce:RC1_3351 ABC transporter, ATP-binding protein; ABC transporter 712071..713072 Actinosynnema mirum DSM 43827 8324807 YP_003098456.1 CDS Amir_0647 NC_013093.1 713069 713752 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vsp:VS_2383 probable D-methionine transport system permease protein MetI; D-methionine ABC transporter permease 713069..713752 Actinosynnema mirum DSM 43827 8324808 YP_003098457.1 CDS Amir_0648 NC_013093.1 713813 714634 D PFAM: NLPA lipoprotein; KEGG: pst:PSPTO_5216 NlpA family lipoprotein; NLPA lipoprotein 713813..714634 Actinosynnema mirum DSM 43827 8324809 YP_003098458.1 CDS Amir_0649 NC_013093.1 714738 715703 D catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 714738..715703 Actinosynnema mirum DSM 43827 8324810 YP_003098459.1 CDS Amir_0650 NC_013093.1 715722 717494 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcb:BCB4264_A2173 ABC transporter, ATP- binding protein; ABC transporter 715722..717494 Actinosynnema mirum DSM 43827 8324811 YP_003098460.1 CDS Amir_0651 NC_013093.1 717693 719588 R KEGG: WIP homolog; hypothetical protein complement(717693..719588) Actinosynnema mirum DSM 43827 8324812 YP_003098461.1 CDS Amir_0652 NC_013093.1 719692 721332 D activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 719692..721332 Actinosynnema mirum DSM 43827 8324813 YP_003098462.1 CDS Amir_0653 NC_013093.1 721456 722025 R KEGG: mxa:MXAN_5077 peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase complement(721456..722025) Actinosynnema mirum DSM 43827 8324814 YP_003098463.1 CDS Amir_0654 NC_013093.1 722015 722497 R hypothetical protein complement(722015..722497) Actinosynnema mirum DSM 43827 8324815 YP_003098464.1 CDS Amir_0655 NC_013093.1 722583 723176 R TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: ribosomal protein L25; KEGG: aeh:Mlg_0284 50S ribosomal protein L25P; ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 complement(722583..723176) Actinosynnema mirum DSM 43827 8324816 YP_003098465.1 CDS Amir_0656 NC_013093.1 723726 724697 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(723726..724697) Actinosynnema mirum DSM 43827 8324817 YP_003098466.1 CDS Amir_0657 NC_013093.1 724714 726189 R TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: glo:Glov_0702 UDP-N-acetylglucosamine pyrophosphorylase; UDP-N-acetylglucosamine pyrophosphorylase complement(724714..726189) Actinosynnema mirum DSM 43827 8324818 YP_003098467.1 CDS Amir_0658 NC_013093.1 726256 727899 R KEGG: hha:Hhal_1304 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase complement(726256..727899) Actinosynnema mirum DSM 43827 8324819 YP_003098468.1 CDS Amir_0659 NC_013093.1 728200 729366 R KEGG: hne:HNE_1191 hypothetical protein; dipeptidylaminopeptidase/acylaminoacyl- peptidase-like protein complement(728200..729366) Actinosynnema mirum DSM 43827 8324821 YP_003098469.1 CDS Amir_0660 NC_013093.1 729521 730510 D PFAM: fatty acid desaturase; KEGG: pfl:PFL_0262 fatty acid desaturase family proteiin; stearoyl-CoA 9-desaturase 729521..730510 Actinosynnema mirum DSM 43827 8324822 YP_003098470.1 CDS Amir_0661 NC_013093.1 730614 731231 D PFAM: regulatory protein TetR; KEGG: mxa:MXAN_5545 transcriptional regulator, TetR family; TetR family transcriptional regulator 730614..731231 Actinosynnema mirum DSM 43827 8324823 YP_003098471.1 CDS Amir_0662 NC_013093.1 731283 731810 D KEGG: hypothetical protein; hypothetical protein 731283..731810 Actinosynnema mirum DSM 43827 8324824 YP_003098472.1 CDS Amir_0663 NC_013093.1 731868 732971 D PFAM: glucose sorbosone dehydrogenase; KEGG: ppd:Ppro_1990 hypothetical protein; glucose sorbosone dehydrogenase 731868..732971 Actinosynnema mirum DSM 43827 8324825 YP_003098473.1 CDS Amir_0664 NC_013093.1 732955 733863 R hypothetical protein complement(732955..733863) Actinosynnema mirum DSM 43827 8324826 YP_003098474.1 CDS Amir_0665 NC_013093.1 734160 737723 D KEGG: gsu:GSU0017 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: transcription factor CarD; helicase domain protein; TRCF domain protein; DEAD/DEAH box helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; transcription-repair coupling factor 734160..737723 Actinosynnema mirum DSM 43827 8324827 YP_003098475.1 CDS Amir_0666 NC_013093.1 737737 738678 D hypothetical protein 737737..738678 Actinosynnema mirum DSM 43827 8324828 YP_003098476.1 CDS Amir_0667 NC_013093.1 738792 739778 D TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: rce:RC1_0140 MazG family protein; MazG family protein 738792..739778 Actinosynnema mirum DSM 43827 8324829 YP_003098477.1 CDS Amir_0668 NC_013093.1 740007 743216 D PFAM: peptidase S41; SMART: peptidase S41; KEGG: swd:Swoo_3891 peptidase S41; peptidase S41 740007..743216 Actinosynnema mirum DSM 43827 8324830 YP_003098478.1 CDS Amir_0669 NC_013093.1 743441 744385 D KEGG: scl:sce1066 hypothetical protein; membrane-bound lytic murein transglycosylase B-like protein 743441..744385 Actinosynnema mirum DSM 43827 8324831 YP_003098479.1 CDS Amir_0670 NC_013093.1 744530 744913 R PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: azc:AZC_2926 hypothetical protein; hypothetical protein complement(744530..744913) Actinosynnema mirum DSM 43827 8324832 YP_003098480.1 CDS Amir_0671 NC_013093.1 745109 746395 D KEGG: nar:Saro_2223 enolase; TIGRFAM: enolase; PFAM: enolase; enolase 745109..746395 Actinosynnema mirum DSM 43827 8324833 YP_003098481.1 CDS Amir_0672 NC_013093.1 746791 747156 D PFAM: septum formation initiator; septum formation initiator 746791..747156 Actinosynnema mirum DSM 43827 8324834 YP_003098482.1 CDS Amir_0673 NC_013093.1 747153 747650 D PFAM: protein of unknown function DUF501; KEGG: csa:Csal_3040 hypothetical protein; hypothetical protein 747153..747650 Actinosynnema mirum DSM 43827 8324835 YP_003098483.1 CDS Amir_0674 NC_013093.1 747861 749165 D KEGG: GI22470 gene product from transcript GI22470- RA; membrane-bound lytic murein transglycosylase B-like protein 747861..749165 Actinosynnema mirum DSM 43827 8324836 YP_003098484.1 CDS Amir_0675 NC_013093.1 749617 750579 D PFAM: Ppx/GppA phosphatase; KEGG: scl:sce1705 hypothetical protein; Ppx/GppA phosphatase 749617..750579 Actinosynnema mirum DSM 43827 8324837 YP_003098485.1 CDS Amir_0676 NC_013093.1 750779 752404 D PFAM: extracellular solute-binding protein family 5; KEGG: bsu:BSU11430 oligopeptide ABC transporter (binding protein); 4-phytase 750779..752404 Actinosynnema mirum DSM 43827 8324838 YP_003098486.1 CDS Amir_0677 NC_013093.1 752475 753401 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dde:Dde_1184 dipeptide ABC transporter, permease protein; dipeptide ABC transporter permease 752475..753401 Actinosynnema mirum DSM 43827 8324839 YP_003098487.1 CDS Amir_0678 NC_013093.1 753394 754317 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bpt:Bpet2850 ABC transporter inner membrane protein; ABC transporter inner membrane protein 753394..754317 Actinosynnema mirum DSM 43827 8324840 YP_003098488.1 CDS Amir_0679 NC_013093.1 754330 755313 D KEGG: mrd:Mrad2831_4369 oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 754330..755313 Actinosynnema mirum DSM 43827 8324841 YP_003098489.1 CDS Amir_0680 NC_013093.1 755306 756304 D KEGG: bbt:BBta_6951 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 755306..756304 Actinosynnema mirum DSM 43827 8324842 YP_003098490.1 CDS Amir_0681 NC_013093.1 756356 757837 R PFAM: peptidase S10 serine carboxypeptidase; KEGG: gur:Gura_2114 peptidase S10, serine carboxypeptidase; peptidase S10 serine carboxypeptidase complement(756356..757837) Actinosynnema mirum DSM 43827 8324843 YP_003098491.1 CDS Amir_0682 NC_013093.1 757874 758704 D PFAM: uracil-DNA glycosylase; KEGG: ank:AnaeK_3689 uracil-DNA glycosylase protein; uracil-DNA glycosylase 757874..758704 Actinosynnema mirum DSM 43827 8324844 YP_003098492.1 CDS Amir_0683 NC_013093.1 758848 759519 D KEGG: gur:Gura_0189 transglutaminase domain- containing protein; hypothetical protein 758848..759519 Actinosynnema mirum DSM 43827 8324845 YP_003098493.1 CDS Amir_0684 NC_013093.1 759516 759977 D hypothetical protein 759516..759977 Actinosynnema mirum DSM 43827 8324846 YP_003098494.1 CDS Amir_0685 NC_013093.1 759974 760927 D PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: sml:Smlt4485 ATPase; ATPase 759974..760927 Actinosynnema mirum DSM 43827 8324847 YP_003098495.1 CDS Amir_0686 NC_013093.1 760924 762228 D PFAM: protein of unknown function DUF58; KEGG: mmr:Mmar10_2677 hypothetical protein; hypothetical protein 760924..762228 Actinosynnema mirum DSM 43827 8324848 YP_003098496.1 CDS Amir_0687 NC_013093.1 762265 763008 D KEGG: GK24882 gene product from transcript GK24882- RA; hypothetical protein 762265..763008 Actinosynnema mirum DSM 43827 8324849 YP_003098497.1 CDS Amir_0688 NC_013093.1 763157 764482 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: rsh:Rsph17029_3442 cyclic nucleotide- regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 763157..764482 Actinosynnema mirum DSM 43827 8324850 YP_003098498.1 CDS Amir_0689 NC_013093.1 764710 764832 D hypothetical protein 764710..764832 Actinosynnema mirum DSM 43827 8324851 YP_003098499.1 CDS Amir_0690 NC_013093.1 764862 766781 D KEGG: hypothetical protein; hypothetical protein 764862..766781 Actinosynnema mirum DSM 43827 8324852 YP_003098500.1 CDS Amir_0691 NC_013093.1 766762 767832 D PFAM: nitroreductase; KEGG: bcz:pE33L466_0413 NADH oxidase; nitroreductase 766762..767832 Actinosynnema mirum DSM 43827 8324853 YP_003098501.1 CDS Amir_0692 NC_013093.1 768231 769874 R PFAM: protein of unknown function DUF885; KEGG: nar:Saro_2356 hypothetical protein; hypothetical protein complement(768231..769874) Actinosynnema mirum DSM 43827 8324855 YP_003098502.1 CDS Amir_0693 NC_013093.1 770041 770664 D KEGG: bid:Bind_2941 hypothetical protein; hypothetical protein 770041..770664 Actinosynnema mirum DSM 43827 8324856 YP_003098503.1 CDS Amir_0694 NC_013093.1 770728 771897 R KEGG: scl:sce7515 hypothetical protein; hypothetical protein complement(770728..771897) Actinosynnema mirum DSM 43827 8324857 YP_003098504.1 CDS Amir_0695 NC_013093.1 771975 772661 R PFAM: peptidase C60 sortase A and B; peptidase C60 sortase A and B complement(771975..772661) Actinosynnema mirum DSM 43827 8324858 YP_003098505.1 CDS Amir_0696 NC_013093.1 772688 774055 R KEGG: bmn:BMA10247_0315 cell division protein FtsK; hypothetical protein complement(772688..774055) Actinosynnema mirum DSM 43827 8324859 YP_003098506.1 CDS Amir_0697 NC_013093.1 774333 775142 D PFAM: protein of unknown function DUF1112; KEGG: xfa:XF2760 hypothetical protein; hypothetical protein 774333..775142 Actinosynnema mirum DSM 43827 8324860 YP_003098507.1 CDS Amir_0698 NC_013093.1 775325 775558 R hypothetical protein complement(775325..775558) Actinosynnema mirum DSM 43827 8324861 YP_003098508.1 CDS Amir_0699 NC_013093.1 775719 776939 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(775719..776939) Actinosynnema mirum DSM 43827 8324862 YP_003098509.1 CDS Amir_0700 NC_013093.1 777141 778511 D KEGG: afw:Anae109_3846 pyridoxal-5'-phosphate- dependent protein beta subunit; TIGRFAM: cystathionine beta-synthase; PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein; cystathionine beta-synthase 777141..778511 Actinosynnema mirum DSM 43827 8324863 YP_003098510.1 CDS Amir_0701 NC_013093.1 778707 779828 D PFAM: hypothetical protein; KEGG: GI11778 gene product from transcript GI11778- RA; hypothetical protein 778707..779828 Actinosynnema mirum DSM 43827 8324864 YP_003098511.1 CDS Amir_0702 NC_013093.1 780021 781172 D PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase; cystathionine gamma-synthase 780021..781172 Actinosynnema mirum DSM 43827 8324865 YP_003098512.1 CDS Amir_0703 NC_013093.1 781277 781549 R KEGG: scl:sce7470 hypothetical protein; hypothetical protein complement(781277..781549) Actinosynnema mirum DSM 43827 8324866 YP_003098513.1 CDS Amir_0704 NC_013093.1 781577 781801 R hypothetical protein complement(781577..781801) Actinosynnema mirum DSM 43827 8324867 YP_003098514.1 CDS Amir_0705 NC_013093.1 781935 783116 R KEGG: bcy:Bcer98_0228 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 4-hydroxyphenylpyruvate dioxygenase complement(781935..783116) Actinosynnema mirum DSM 43827 8324868 YP_003098515.1 CDS Amir_0706 NC_013093.1 783192 783713 D PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: ppg:PputGB1_0412 AsnC family transcriptional regulator; AsnC family transcriptional regulator 783192..783713 Actinosynnema mirum DSM 43827 8324869 YP_003098516.1 CDS Amir_0707 NC_013093.1 783930 784418 R TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: wol:WD0654 transcription elongation factor GreA; transcription elongation factor GreA complement(783930..784418) Actinosynnema mirum DSM 43827 8324870 YP_003098517.1 CDS Amir_0708 NC_013093.1 784632 785051 R hypothetical protein complement(784632..785051) Actinosynnema mirum DSM 43827 8324871 YP_003098518.1 CDS Amir_0709 NC_013093.1 785161 786042 D TIGRFAM: mycothiol conjugate amidase Mca; PFAM: LmbE family protein; KEGG: aba:Acid345_2880 LmbE-like protein; mycothiol conjugate amidase Mca 785161..786042 Actinosynnema mirum DSM 43827 8324872 YP_003098519.1 CDS Amir_0710 NC_013093.1 786039 786398 D KEGG: SAT2; serine O-acetyl transferase; K00640 serine O-acetyltransferase; hypothetical protein 786039..786398 Actinosynnema mirum DSM 43827 8324873 YP_003098520.1 CDS Amir_0711 NC_013093.1 786435 786995 R PFAM: protein of unknown function DUF1526; KEGG: rru:Rru_A1986 hypothetical protein; hypothetical protein complement(786435..786995) Actinosynnema mirum DSM 43827 8324874 YP_003098521.1 CDS Amir_0712 NC_013093.1 787541 789514 D PFAM: protein of unknown function DUF255; KEGG: xau:Xaut_1832 hypothetical protein; hypothetical protein 787541..789514 Actinosynnema mirum DSM 43827 8324875 YP_003098522.1 CDS Amir_0713 NC_013093.1 789566 790243 R TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: afw:Anae109_1200 hemolysin III family channel protein; channel protein, hemolysin III family complement(789566..790243) Actinosynnema mirum DSM 43827 8324876 YP_003098523.1 CDS Amir_0714 NC_013093.1 790326 791105 D KEGG: bcj:BCAM2067 undecaprenyl pyrophosphate synthetase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase 790326..791105 Actinosynnema mirum DSM 43827 8324877 YP_003098524.1 CDS Amir_0715 NC_013093.1 791335 791661 R KEGG: abb:ABBFA_000474 outer membrane protein A precursor (190 kDa antigen); outer membrane protein A (190 kDa antigen) complement(791335..791661) Actinosynnema mirum DSM 43827 8324878 YP_003098525.1 CDS Amir_0716 NC_013093.1 791836 793074 D KEGG: sal:Sala_0599 hypothetical protein; hypothetical protein 791836..793074 Actinosynnema mirum DSM 43827 8324879 YP_003098526.1 CDS Amir_0717 NC_013093.1 793447 794823 D PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; KEGG: dal:Dalk_3397 PhoH family protein; PhoH family protein 793447..794823 Actinosynnema mirum DSM 43827 8324880 YP_003098527.1 CDS Amir_0718 NC_013093.1 794926 796359 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase complement(794926..796359) Actinosynnema mirum DSM 43827 8324881 YP_003098528.1 CDS ligB NC_013093.1 796372 797985 R catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase complement(796372..797985) Actinosynnema mirum DSM 43827 8324882 YP_003098529.1 CDS fumC NC_013093.1 798086 799480 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(798086..799480) Actinosynnema mirum DSM 43827 8324883 YP_003098530.1 CDS Amir_0721 NC_013093.1 799546 800517 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bha:BH3408 thioredoxin reductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 799546..800517 Actinosynnema mirum DSM 43827 8324884 YP_003098531.1 CDS Amir_0722 NC_013093.1 800609 801043 R PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: xca:xccb100_2984 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein complement(800609..801043) Actinosynnema mirum DSM 43827 8324885 YP_003098532.1 CDS Amir_0723 NC_013093.1 801210 801974 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap complement(801210..801974) Actinosynnema mirum DSM 43827 8324886 YP_003098533.1 CDS glpX NC_013093.1 802130 803182 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(802130..803182) Actinosynnema mirum DSM 43827 8324887 YP_003098534.1 CDS Amir_0725 NC_013093.1 803231 803440 R TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: exonuclease VII small subunit; KEGG: AGAP012846-PA; exodeoxyribonuclease VII, small subunit complement(803231..803440) Actinosynnema mirum DSM 43827 8324888 YP_003098535.1 CDS Amir_0726 NC_013093.1 803437 803847 R KEGG: scl:sce2186 hypothetical protein; hypothetical protein complement(803437..803847) Actinosynnema mirum DSM 43827 8324889 YP_003098536.1 CDS Amir_0727 NC_013093.1 803828 805090 R KEGG: hha:Hhal_1683 exodeoxyribonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: exonuclease VII large subunit; nucleic acid binding OB-fold tRNA/helicase-type; exodeoxyribonuclease VII, large subunit complement(803828..805090) Actinosynnema mirum DSM 43827 8324890 YP_003098537.1 CDS Amir_0728 NC_013093.1 805087 805716 R KEGG: GM22731 gene product from transcript GM22731- RA; hypothetical protein complement(805087..805716) Actinosynnema mirum DSM 43827 8324891 YP_003098538.1 CDS ispH NC_013093.1 805781 806725 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 805781..806725 Actinosynnema mirum DSM 43827 8324892 YP_003098539.1 CDS Amir_0730 NC_013093.1 807024 807767 R KEGG: DNA helicase (SGS1 homologue); K03654 ATP- dependent DNA helicase RecQ; hypothetical protein complement(807024..807767) Actinosynnema mirum DSM 43827 8324893 YP_003098540.1 CDS Amir_0731 NC_013093.1 807869 808810 R PFAM: protein of unknown function DUF195; KEGG: afw:Anae109_0527 hypothetical protein; hypothetical protein complement(807869..808810) Actinosynnema mirum DSM 43827 8324894 YP_003098541.1 CDS Amir_0732 NC_013093.1 808913 810061 D TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: afw:Anae109_2145 nuclease SbcCD, D subunit; nuclease SbcCD, D subunit 808913..810061 Actinosynnema mirum DSM 43827 8324895 YP_003098542.1 CDS Amir_0733 NC_013093.1 810058 812946 D KEGG: afw:Anae109_2144 DNA repair exonuclease, SbcC; DNA repair exonuclease, SbcC 810058..812946 Actinosynnema mirum DSM 43827 8324896 YP_003098543.1 CDS Amir_0734 NC_013093.1 812974 813468 R TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; KEGG: sus:Acid_4002 methylated-DNA--protein- cysteine methyltransferase; methylated-DNA/protein- cysteinemethyltransferase complement(812974..813468) Actinosynnema mirum DSM 43827 8324897 YP_003098544.1 CDS Amir_0735 NC_013093.1 813465 814790 R KEGG: scl:sce6205 regulatory protein Ada; PFAM: AlkA domain protein; Ada metal-binding domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; AraC family transcriptional regulator complement(813465..814790) Actinosynnema mirum DSM 43827 8324898 YP_003098545.1 CDS Amir_0736 NC_013093.1 814869 815948 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 814869..815948 Actinosynnema mirum DSM 43827 8324899 YP_003098546.1 CDS Amir_0737 NC_013093.1 816499 816972 D hypothetical protein 816499..816972 Actinosynnema mirum DSM 43827 8324900 YP_003098547.1 CDS Amir_0738 NC_013093.1 816990 817316 D hypothetical protein 816990..817316 Actinosynnema mirum DSM 43827 8324901 YP_003098548.1 CDS Amir_0739 NC_013093.1 817485 818147 R KEGG: hypothetical protein; hypothetical protein complement(817485..818147) Actinosynnema mirum DSM 43827 8324902 YP_003098549.1 CDS Amir_0740 NC_013093.1 818390 818743 R hypothetical protein complement(818390..818743) Actinosynnema mirum DSM 43827 8324903 YP_003098550.1 CDS Amir_0741 NC_013093.1 818803 819153 R hypothetical protein complement(818803..819153) Actinosynnema mirum DSM 43827 8324904 YP_003098551.1 CDS Amir_0742 NC_013093.1 819606 819710 R hypothetical protein complement(819606..819710) Actinosynnema mirum DSM 43827 8324905 YP_003098552.1 CDS pimE NC_013093.1 819816 821012 D involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis; mannosyltransferase 819816..821012 Actinosynnema mirum DSM 43827 8324906 YP_003098553.1 CDS Amir_0745 NC_013093.1 821250 821543 R PFAM: transcriptional coactivator/pterin dehydratase; KEGG: mxa:MXAN_6773 pterin-4-alpha- carbinolamine dehydratase; transcriptional coactivator/pterin dehydratase complement(821250..821543) Actinosynnema mirum DSM 43827 8324908 YP_003098554.1 CDS Amir_0746 NC_013093.1 821679 822713 D TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; PFAM: extracellular solute-binding protein family 1; KEGG: cvi:CV_3164 thiamin-binding periplasmic protein; ABC transporter periplasmic protein 821679..822713 Actinosynnema mirum DSM 43827 8324909 YP_003098555.1 CDS Amir_0747 NC_013093.1 822803 824446 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rfr:Rfer_3245 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 822803..824446 Actinosynnema mirum DSM 43827 8324910 YP_003098556.1 CDS Amir_0748 NC_013093.1 824446 825447 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bra:BRADO7092 spermidine/putrescine ABC transporter ATP-binding protein; ABC transporter 824446..825447 Actinosynnema mirum DSM 43827 8324911 YP_003098557.1 CDS Amir_0749 NC_013093.1 825493 826359 R KEGG: aeh:Mlg_1077 ABC-type transport system involved in multi-copper enzyme maturation, permease component; hypothetical protein complement(825493..826359) Actinosynnema mirum DSM 43827 8324912 YP_003098558.1 CDS Amir_0750 NC_013093.1 826356 829865 R KEGG: proteophosphoglycan 5; hypothetical protein complement(826356..829865) Actinosynnema mirum DSM 43827 8324913 YP_003098559.1 CDS Amir_0751 NC_013093.1 829862 830890 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH0445 ABC transporter ATP-binding protein; ABC transporter complement(829862..830890) Actinosynnema mirum DSM 43827 8324914 YP_003098560.1 CDS Amir_0752 NC_013093.1 830887 832089 R KEGG: pau:PA14_50860 hypothetical protein; hypothetical protein complement(830887..832089) Actinosynnema mirum DSM 43827 8324915 YP_003098561.1 CDS Amir_0753 NC_013093.1 832249 832974 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: met:M446_6140 two component transcriptional regulator; winged helix family two component transcriptional regulator 832249..832974 Actinosynnema mirum DSM 43827 8324916 YP_003098562.1 CDS Amir_0754 NC_013093.1 832971 834254 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase 832971..834254 Actinosynnema mirum DSM 43827 8324917 YP_003098563.1 CDS Amir_0755 NC_013093.1 834452 835255 D PFAM: NUDIX hydrolase; KEGG: scl:sce8529 Nudix/MutT family protein; NUDIX hydrolase 834452..835255 Actinosynnema mirum DSM 43827 8324918 YP_003098564.1 CDS Amir_0756 NC_013093.1 835671 836636 R KEGG: hsm:HSM_0044 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; tryptophanyl-tRNA synthetase complement(835671..836636) Actinosynnema mirum DSM 43827 8324919 YP_003098565.1 CDS Amir_0757 NC_013093.1 836836 837138 D PFAM: YCII-related; KEGG: bpy:Bphyt_0556 YCII-related; YCII-like protein 836836..837138 Actinosynnema mirum DSM 43827 8324920 YP_003098566.1 CDS Amir_0758 NC_013093.1 837484 837645 R hypothetical protein complement(837484..837645) Actinosynnema mirum DSM 43827 8324921 YP_003098567.1 CDS Amir_0759 NC_013093.1 837810 839711 D TIGRFAM: GTP-binding protein TypA; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: aba:Acid345_4404 GTP-binding protein TypA; GTP-binding protein TypA 837810..839711 Actinosynnema mirum DSM 43827 8324922 YP_003098568.1 CDS Amir_0760 NC_013093.1 839987 841687 D PFAM: extracellular solute-binding protein family 5; KEGG: mes:Meso_1835 extracellular solute-binding protein, family 5; family 5 extracellular solute-binding protein 839987..841687 Actinosynnema mirum DSM 43827 8324923 YP_003098569.1 CDS Amir_0761 NC_013093.1 841988 843802 D PFAM: extracellular solute-binding protein family 5; KEGG: mes:Meso_1835 extracellular solute-binding protein, family 5; family 5 extracellular solute-binding protein 841988..843802 Actinosynnema mirum DSM 43827 8324924 YP_003098570.1 CDS Amir_0762 NC_013093.1 843963 844961 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_1834 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 843963..844961 Actinosynnema mirum DSM 43827 8324925 YP_003098571.1 CDS Amir_0763 NC_013093.1 844963 845901 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_1833 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 844963..845901 Actinosynnema mirum DSM 43827 8324926 YP_003098572.1 CDS Amir_0764 NC_013093.1 845898 847076 D KEGG: bcs:BCAN_B1102 oligopeptide/dipeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 845898..847076 Actinosynnema mirum DSM 43827 8324927 YP_003098573.1 CDS Amir_0765 NC_013093.1 847073 848122 D KEGG: bra:BRADO1097 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 847073..848122 Actinosynnema mirum DSM 43827 8324928 YP_003098574.1 CDS Amir_0766 NC_013093.1 848250 849101 D TIGRFAM:1D-myo-inosityl-2-acetamido-2-deoxy-alpha- D- glucopyranosidedeacetylase; PFAM: LmbE family protein; KEGG: aba:Acid345_2880 LmbE-like protein; 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranosidedeacetylase 848250..849101 Actinosynnema mirum DSM 43827 8324929 YP_003098575.1 CDS Amir_0767 NC_013093.1 849200 849580 D hypothetical protein 849200..849580 Actinosynnema mirum DSM 43827 8324930 YP_003098576.1 CDS Amir_0768 NC_013093.1 849761 850825 D KEGG: met:M446_5119 flagellar hook-length control protein; hypothetical protein 849761..850825 Actinosynnema mirum DSM 43827 8324931 YP_003098577.1 CDS Amir_0769 NC_013093.1 850804 851637 R PFAM: GCN5-related N-acetyltransferase; KEGG: ccs:CCNA_02292 acetyltransferase; GCN5-like N-acetyltransferase complement(850804..851637) Actinosynnema mirum DSM 43827 8324932 YP_003098578.1 CDS Amir_0770 NC_013093.1 851796 852122 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: vei:Veis_3502 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 851796..852122 Actinosynnema mirum DSM 43827 8324933 YP_003098579.1 CDS Amir_0771 NC_013093.1 852119 853210 D PFAM: aminotransferase class I and II; KEGG: afw:Anae109_3944 aminotransferase class I and II; class I and II aminotransferase 852119..853210 Actinosynnema mirum DSM 43827 8324934 YP_003098580.1 CDS Amir_0772 NC_013093.1 853292 854266 R KEGG: vch:VC2329 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase; 2,3,4, 5-tetrahydropyridine-2-carboxylateN-succinyltransferase complement(853292..854266) Actinosynnema mirum DSM 43827 8324935 YP_003098581.1 CDS Amir_0773 NC_013093.1 854283 855362 D catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 854283..855362 Actinosynnema mirum DSM 43827 8324936 YP_003098582.1 CDS Amir_0774 NC_013093.1 855382 856149 D PFAM: conserved hypothetical protein; KEGG: hypothetical protein; hypothetical protein 855382..856149 Actinosynnema mirum DSM 43827 8324937 YP_003098583.1 CDS Amir_0775 NC_013093.1 856149 856691 D PFAM: conserved hypothetical protein; KEGG: mpt:Mpe_A2111 hypothetical protein; hypothetical protein 856149..856691 Actinosynnema mirum DSM 43827 8324938 YP_003098584.1 CDS Amir_0776 NC_013093.1 856763 858316 R PFAM: peptidase S15; X-Pro dipeptidyl-peptidase domain protein; acetyl xylan esterase; KEGG: sml:Smlt2609 X-Pro dipeptidyl- peptidase protein; peptidase S15 complement(856763..858316) Actinosynnema mirum DSM 43827 8324939 YP_003098585.1 CDS Amir_0777 NC_013093.1 858410 859270 D KEGG: ade:Adeh_1496 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; dihydropteroate synthase 858410..859270 Actinosynnema mirum DSM 43827 8324940 YP_003098586.1 CDS Amir_0778 NC_013093.1 859337 859684 D PFAM: transcriptional regulator PadR family protein; KEGG: aba:Acid345_4626 transcriptional regulator, PadR family; PadR family transcriptional regulator 859337..859684 Actinosynnema mirum DSM 43827 8324941 YP_003098587.1 CDS Amir_0779 NC_013093.1 859772 860347 D KEGG: GD17417 gene product from transcript GD17417- RA; hypothetical protein 859772..860347 Actinosynnema mirum DSM 43827 8324942 YP_003098588.1 CDS Amir_0780 NC_013093.1 860334 860765 D hypothetical protein 860334..860765 Actinosynnema mirum DSM 43827 8324943 YP_003098589.1 CDS Amir_0781 NC_013093.1 860768 861346 D KEGG: tmz:Tmz1t_2227 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase; DNA-3-methyladenine glycosylase I 860768..861346 Actinosynnema mirum DSM 43827 8324944 YP_003098590.1 CDS Amir_0782 NC_013093.1 861347 862234 R PFAM: regulatory protein TetR; KEGG: ccs:CCNA_02424 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(861347..862234) Actinosynnema mirum DSM 43827 8324945 YP_003098591.1 CDS Amir_0783 NC_013093.1 862339 863382 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bph:Bphy_2359 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 862339..863382 Actinosynnema mirum DSM 43827 8324946 YP_003098592.1 CDS Amir_0784 NC_013093.1 863379 863972 D PFAM: regulatory protein TetR; KEGG: cak:Caul_3929 TetR family transcriptional regulator; TetR family transcriptional regulator 863379..863972 Actinosynnema mirum DSM 43827 8324947 YP_003098593.1 CDS Amir_0785 NC_013093.1 864008 864613 D KEGG: met:M446_0017 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 864008..864613 Actinosynnema mirum DSM 43827 8324948 YP_003098594.1 CDS Amir_0786 NC_013093.1 864738 865520 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: dac:Daci_0568 enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase complement(864738..865520) Actinosynnema mirum DSM 43827 8324949 YP_003098595.1 CDS Amir_0787 NC_013093.1 865668 866474 R PFAM: PaaX domain protein domain; PaaX domain protein; KEGG: bha:BH0194 repressor in the phenylacetic acid catabolic pathway; PaaX family transcriptional regulator complement(865668..866474) Actinosynnema mirum DSM 43827 8324950 YP_003098596.1 CDS Amir_0788 NC_013093.1 866738 866905 D hypothetical protein 866738..866905 Actinosynnema mirum DSM 43827 8324951 YP_003098597.1 CDS Amir_0789 NC_013093.1 867012 868379 D PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: rce:RC1_1566 leucyl aminopeptidase PepA; Leucyl aminopeptidase 867012..868379 Actinosynnema mirum DSM 43827 8324952 YP_003098598.1 CDS Amir_0790 NC_013093.1 868404 869489 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bsu:BSU40670 hypothetical protein; LysR family transcriptional regulator complement(868404..869489) Actinosynnema mirum DSM 43827 8324953 YP_003098599.1 CDS Amir_0791 NC_013093.1 869516 870820 D PFAM: major facilitator superfamily MFS_1; KEGG: acr:Acry_1491 major facilitator transporter; major facilitator superfamily protein 869516..870820 Actinosynnema mirum DSM 43827 8324954 YP_003098600.1 CDS Amir_0793 NC_013093.1 872197 873384 R TIGRFAM: glycogen synthase; PFAM: glycosyl transferase group 1; KEGG: bmj:BMULJ_06045 glycosyltransferase; glycogen synthase complement(872197..873384) Actinosynnema mirum DSM 43827 8324956 YP_003098601.1 CDS Amir_0794 NC_013093.1 873475 874695 D TIGRFAM: glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; KEGG: mxa:MXAN_1524 glucose-1-phosphate adenylyltransferase; glucose-1-phosphate adenylyltransferase 873475..874695 Actinosynnema mirum DSM 43827 8324957 YP_003098602.1 CDS Amir_0795 NC_013093.1 875108 875692 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: sus:Acid_0793 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 875108..875692 Actinosynnema mirum DSM 43827 8324958 YP_003098603.1 CDS Amir_0796 NC_013093.1 875689 876336 D KEGG: similar to sperm associated antigen 8 isoform 2; transmembrane anti-sigma factor 875689..876336 Actinosynnema mirum DSM 43827 8324959 YP_003098604.1 CDS Amir_0797 NC_013093.1 876404 877942 D PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: rfr:Rfer_2959 peptidase S1 and S6, chymotrypsin/Hap; peptidase S1 and S6 chymotrypsin/Hap 876404..877942 Actinosynnema mirum DSM 43827 8324960 YP_003098605.1 CDS Amir_0798 NC_013093.1 878054 878443 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 878054..878443 Actinosynnema mirum DSM 43827 8324961 YP_003098606.1 CDS Amir_0799 NC_013093.1 878625 879770 R PFAM: protein of unknown function DUF59; KEGG: bcr:BCAH187_A3588 mrp protein; hypothetical protein complement(878625..879770) Actinosynnema mirum DSM 43827 8324962 YP_003098607.1 CDS Amir_0800 NC_013093.1 879919 880422 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: pst:PSPTO_3861 MarR family transcriptional regulator; MarR family transcriptional regulator 879919..880422 Actinosynnema mirum DSM 43827 8324963 YP_003098608.1 CDS Amir_0801 NC_013093.1 880438 881028 R PFAM: protein of unknown function DUF1003; KEGG: ppf:Pput_1917 hypothetical protein; hypothetical protein complement(880438..881028) Actinosynnema mirum DSM 43827 8324964 YP_003098609.1 CDS Amir_0802 NC_013093.1 881021 882271 R PFAM: MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: gur:Gura_2041 MgtE intracellular region; MgtE intracellular region complement(881021..882271) Actinosynnema mirum DSM 43827 8324965 YP_003098610.1 CDS Amir_0803 NC_013093.1 882299 883156 R PFAM: aminoglycoside/hydroxyurea antibiotic resistance kinase; KEGG: pap:PSPA7_3432 streptomycin 3''-kinase (streptomycin 3''-phosphotransferase) (SPH); aminoglycoside/hydroxyurea antibiotic resistance kinase complement(882299..883156) Actinosynnema mirum DSM 43827 8324966 YP_003098611.1 CDS Amir_0804 NC_013093.1 883153 883473 R hypothetical protein complement(883153..883473) Actinosynnema mirum DSM 43827 8324967 YP_003098612.1 CDS Amir_0805 NC_013093.1 883598 884557 D PFAM: HpcH/HpaI aldolase; KEGG: sil:SPO1565 citrate lyase; Citrate (pro-3S)-lyase 883598..884557 Actinosynnema mirum DSM 43827 8324968 YP_003098613.1 CDS Amir_0806 NC_013093.1 884815 885354 D KEGG: har:HEAR2359 permease; hypothetical protein 884815..885354 Actinosynnema mirum DSM 43827 8324969 YP_003098614.1 CDS Amir_0807 NC_013093.1 885780 887042 D PFAM: extracellular solute-binding protein family 1; KEGG: noc:Noc_0282 extracellular solute-binding protein; family 1 extracellular solute-binding protein 885780..887042 Actinosynnema mirum DSM 43827 8324970 YP_003098615.1 CDS Amir_0808 NC_013093.1 887039 887995 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: noc:Noc_0281 ABC transporter, inner membrane subunit; ABC transporter inner membrane protein 887039..887995 Actinosynnema mirum DSM 43827 8324971 YP_003098616.1 CDS Amir_0809 NC_013093.1 887995 888840 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: noc:Noc_0280 ABC transporter, inner membrane subunit; ABC transporter inner membrane protein 887995..888840 Actinosynnema mirum DSM 43827 8324972 YP_003098617.1 CDS Amir_0810 NC_013093.1 888841 890031 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: noc:Noc_0279 ABC transporter, ATPase subunit; ABC transporter 888841..890031 Actinosynnema mirum DSM 43827 8324973 YP_003098618.1 CDS Amir_0811 NC_013093.1 890368 891258 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rpb:RPB_3589 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 890368..891258 Actinosynnema mirum DSM 43827 8324974 YP_003098619.1 CDS Amir_0812 NC_013093.1 891313 892278 D hypothetical protein 891313..892278 Actinosynnema mirum DSM 43827 8324975 YP_003098620.1 CDS Amir_0813 NC_013093.1 892336 892941 D PFAM: transcriptional regulator PadR family protein; KEGG: bmj:BMULJ_03145 PadR-like family transcriptional regulator; PadR family transcriptional regulator 892336..892941 Actinosynnema mirum DSM 43827 8324976 YP_003098621.1 CDS Amir_0814 NC_013093.1 893043 894131 D KEGG: mno:Mnod_7454 hypothetical protein; hypothetical protein 893043..894131 Actinosynnema mirum DSM 43827 8324977 YP_003098622.1 CDS Amir_0815 NC_013093.1 894210 894305 R hypothetical protein complement(894210..894305) Actinosynnema mirum DSM 43827 8324978 YP_003098623.1 CDS Amir_0816 NC_013093.1 894345 895448 R TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: reh:H16_A0087 Mg2+ and Co2+ transporter; magnesium and cobalt transport protein CorA complement(894345..895448) Actinosynnema mirum DSM 43827 8324979 YP_003098624.1 CDS Amir_0817 NC_013093.1 895981 897048 D KEGG: sil:SPO0916 hypothetical protein; hypothetical protein 895981..897048 Actinosynnema mirum DSM 43827 8324980 YP_003098625.1 CDS Amir_0818 NC_013093.1 897890 898048 D hypothetical protein 897890..898048 Actinosynnema mirum DSM 43827 8324981 YP_003098626.1 CDS Amir_0819 NC_013093.1 898098 898658 D PFAM: membrane-flanked domain; KEGG: acr:Acry_0579 membrane-flanked domain- containing protein; membrane-flanked domain-containing protein 898098..898658 Actinosynnema mirum DSM 43827 8324982 YP_003098627.1 CDS Amir_0820 NC_013093.1 898676 899533 D PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: mxa:MXAN_2739 hypothetical protein; PHP domain-containing protein 898676..899533 Actinosynnema mirum DSM 43827 8324983 YP_003098628.1 CDS Amir_0821 NC_013093.1 899938 900777 D KEGG: mxa:MXAN_1877 hypothetical protein; hypothetical protein 899938..900777 Actinosynnema mirum DSM 43827 8324984 YP_003098629.1 CDS Amir_0822 NC_013093.1 901612 902448 R PFAM: alpha/beta hydrolase fold; KEGG: met:M446_0531 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein complement(901612..902448) Actinosynnema mirum DSM 43827 8324985 YP_003098630.1 CDS Amir_0823 NC_013093.1 902513 903991 R KEGG: dno:DNO_0690 hypothetical protein; hypothetical protein complement(902513..903991) Actinosynnema mirum DSM 43827 8324986 YP_003098631.1 CDS Amir_0824 NC_013093.1 904032 905861 R PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: rle:RL3597 DEAD box ATP-dependent RNA helicase protein; DEAD/DEAH box helicase domain-containing protein complement(904032..905861) Actinosynnema mirum DSM 43827 8324987 YP_003098632.1 CDS Amir_0825 NC_013093.1 906189 906866 D hypothetical protein 906189..906866 Actinosynnema mirum DSM 43827 8324988 YP_003098633.1 CDS Amir_0826 NC_013093.1 906909 907136 D hypothetical protein 906909..907136 Actinosynnema mirum DSM 43827 8324989 YP_003098634.1 CDS Amir_0827 NC_013093.1 907308 907700 R hypothetical protein complement(907308..907700) Actinosynnema mirum DSM 43827 8324990 YP_003098635.1 CDS Amir_0828 NC_013093.1 907697 908524 R PFAM: regulatory protein TetR; KEGG: mxa:MXAN_5545 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(907697..908524) Actinosynnema mirum DSM 43827 8324991 YP_003098636.1 CDS Amir_0829 NC_013093.1 908586 909485 D KEGG: afr:AFE_2323 hypothetical protein; hypothetical protein 908586..909485 Actinosynnema mirum DSM 43827 8324992 YP_003098637.1 CDS Amir_0830 NC_013093.1 909527 910171 R PFAM: regulatory protein TetR; KEGG: mxa:MXAN_5545 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(909527..910171) Actinosynnema mirum DSM 43827 8324993 YP_003098638.1 CDS Amir_0831 NC_013093.1 910283 911317 D PFAM: alpha/beta hydrolase fold; KEGG: rsp:RSP_1258 hydrolase; alpha/beta hydrolase fold protein 910283..911317 Actinosynnema mirum DSM 43827 8324994 YP_003098639.1 CDS Amir_0832 NC_013093.1 911388 912422 D hypothetical protein 911388..912422 Actinosynnema mirum DSM 43827 8324995 YP_003098640.1 CDS Amir_0833 NC_013093.1 912541 913713 D The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; molybdopterin biosynthesis-like protein MoeZ 912541..913713 Actinosynnema mirum DSM 43827 8324996 YP_003098641.1 CDS Amir_0834 NC_013093.1 914297 915115 D PFAM: aminoglycoside phosphotransferase; KEGG: rle:RL1223 hypothetical protein; aminoglycoside phosphotransferase 914297..915115 Actinosynnema mirum DSM 43827 8324997 YP_003098642.1 CDS Amir_0835 NC_013093.1 915248 917281 D PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: msl:Msil_3772 molybdopterin oxidoreductase; molybdopterin oxidoreductase 915248..917281 Actinosynnema mirum DSM 43827 8324998 YP_003098643.1 CDS Amir_0836 NC_013093.1 917496 918983 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: scl:sce3488 nitrite reductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 917496..918983 Actinosynnema mirum DSM 43827 8324999 YP_003098644.1 CDS Amir_0837 NC_013093.1 919254 920606 D PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr2806 nitrite extrusion protein; major facilitator superfamily protein 919254..920606 Actinosynnema mirum DSM 43827 8325000 YP_003098645.1 CDS Amir_0838 NC_013093.1 920982 923486 D TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: bam:Bamb_3936 nitrite reductase (NAD(P)H), large subunit; nitrite reductase (NAD(P)H), large subunit 920982..923486 Actinosynnema mirum DSM 43827 8325001 YP_003098646.1 CDS Amir_0839 NC_013093.1 923501 923893 D TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: mfa:Mfla_0318 nitrite reductase (NAD(P)H) large subunit, NirD; nitrite reductase (NAD(P)H), small subunit 923501..923893 Actinosynnema mirum DSM 43827 8325002 YP_003098647.1 CDS Amir_0840 NC_013093.1 923932 925077 D PFAM: uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: scl:sce6449 transcriptional regulator; uroporphyrinogen III synthase HEM4 923932..925077 Actinosynnema mirum DSM 43827 8325003 YP_003098648.1 CDS Amir_0841 NC_013093.1 925074 925832 D PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 transmembrane protein; cobalamin (vitamin B12) biosynthesis CbiX protein 925074..925832 Actinosynnema mirum DSM 43827 8325004 YP_003098649.1 CDS Amir_0842 NC_013093.1 925944 926273 R hypothetical protein complement(925944..926273) Actinosynnema mirum DSM 43827 8325005 YP_003098650.1 CDS Amir_0843 NC_013093.1 926722 927141 R hypothetical protein complement(926722..927141) Actinosynnema mirum DSM 43827 8325006 YP_003098651.1 CDS Amir_0844 NC_013093.1 927294 927980 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pst:PSPTO_1307 DNA-binding heavy metal response regulator; winged helix family two component transcriptional regulator 927294..927980 Actinosynnema mirum DSM 43827 8325007 YP_003098652.1 CDS Amir_0845 NC_013093.1 927977 929347 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gsu:GSU0452 sensor histidine kinase; histidine kinase 927977..929347 Actinosynnema mirum DSM 43827 8325008 YP_003098653.1 CDS Amir_0846 NC_013093.1 929344 929691 R hypothetical protein complement(929344..929691) Actinosynnema mirum DSM 43827 8325009 YP_003098654.1 CDS Amir_0847 NC_013093.1 929748 930827 R PFAM: TrkA-N domain protein; Ion transport 2 domain protein; KEGG: bpy:Bphyt_4906 TrkA-N domain protein; TrkA-N domain-containing protein complement(929748..930827) Actinosynnema mirum DSM 43827 8325010 YP_003098655.1 CDS Amir_0848 NC_013093.1 930827 932266 R PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: mgm:Mmc1_1548 peptidase M20; peptidase M20 complement(930827..932266) Actinosynnema mirum DSM 43827 8325011 YP_003098656.1 CDS Amir_0849 NC_013093.1 932326 932709 D KEGG: mxa:MXAN_6481 hypothetical protein; hypothetical protein 932326..932709 Actinosynnema mirum DSM 43827 8325012 YP_003098657.1 CDS Amir_0850 NC_013093.1 932790 933335 D hypothetical protein 932790..933335 Actinosynnema mirum DSM 43827 8325013 YP_003098658.1 CDS Amir_0851 NC_013093.1 933357 937406 R PFAM: UvrD/REP helicase; KEGG: xau:Xaut_0776 UvrD/REP helicase; UvrD/REP helicase complement(933357..937406) Actinosynnema mirum DSM 43827 8325014 YP_003098659.1 CDS Amir_0852 NC_013093.1 937928 941080 R PFAM: UvrD/REP helicase; KEGG: ank:AnaeK_0104 UvrD/REP helicase; UvrD/REP helicase complement(937928..941080) Actinosynnema mirum DSM 43827 8325015 YP_003098660.1 CDS Amir_0853 NC_013093.1 941213 941548 D PFAM: methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; KEGG: aci:ACIAD2864 methyltransferase; methylated-DNA-(protein)-cysteine S- methyltransferase DNA binding 941213..941548 Actinosynnema mirum DSM 43827 8325016 YP_003098661.1 CDS Amir_0854 NC_013093.1 941628 941996 R SMART: hypothetical protein; KEGG: oca:OCAR_7425 TPR repeat protein; hypothetical protein complement(941628..941996) Actinosynnema mirum DSM 43827 8325017 YP_003098662.1 CDS Amir_0855 NC_013093.1 942082 942825 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mll2196 short chain oxidoreductase; short-chain dehydrogenase/reductase SDR complement(942082..942825) Actinosynnema mirum DSM 43827 8325018 YP_003098663.1 CDS Amir_0856 NC_013093.1 942907 943812 D PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: scl:sce1423 LysR family transcriptional regulator; LysR family transcriptional regulator 942907..943812 Actinosynnema mirum DSM 43827 8325019 YP_003098664.1 CDS Amir_0857 NC_013093.1 943891 944799 R PFAM: protein of unknown function zinc metallopeptidase KEGG: atc:AGR_C_3948 conserved hypothetical protein PA4717; hypothetical protein complement(943891..944799) Actinosynnema mirum DSM 43827 8325020 YP_003098665.1 CDS Amir_0858 NC_013093.1 944829 945872 R PFAM: protein of unknown function zinc metallopeptidase KEGG: dno:DNO_0928 hypothetical protein; hypothetical protein complement(944829..945872) Actinosynnema mirum DSM 43827 8325021 YP_003098666.1 CDS Amir_0859 NC_013093.1 946230 947879 D KEGG: hypothetical protein; hypothetical protein 946230..947879 Actinosynnema mirum DSM 43827 8325022 YP_003098667.1 CDS Amir_0860 NC_013093.1 948072 948344 R PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; KEGG: pen:PSEEN1871 DNA-binding protein HU-beta; histone family protein DNA-binding protein complement(948072..948344) Actinosynnema mirum DSM 43827 8325023 YP_003098668.1 CDS Amir_0861 NC_013093.1 948618 949157 R PFAM: protein of unknown function DUF1470; KEGG: bcm:Bcenmc03_4753 hypothetical protein; hypothetical protein complement(948618..949157) Actinosynnema mirum DSM 43827 8325024 YP_003098669.1 CDS Amir_0862 NC_013093.1 949248 950123 D PFAM: alpha/beta hydrolase fold; KEGG: msl:Msil_2561 alpha/beta hydrolase fold protein; alpha/beta hydrolase fold protein 949248..950123 Actinosynnema mirum DSM 43827 8325025 YP_003098670.1 CDS Amir_0863 NC_013093.1 950249 951535 D PFAM: peptidase M16 domain protein; KEGG: afw:Anae109_0081 peptidase M16 domain- containing protein; peptidase M16 domain-containing protein 950249..951535 Actinosynnema mirum DSM 43827 8325026 YP_003098671.1 CDS Amir_0864 NC_013093.1 951532 952920 D PFAM: peptidase M16 domain protein; KEGG: mxa:MXAN_1624 peptidase, M16 (pitrilysin) family; peptidase M16 domain-containing protein 951532..952920 Actinosynnema mirum DSM 43827 8325027 YP_003098672.1 CDS Amir_0865 NC_013093.1 952917 953876 D PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: xcv:XCV0537 NUDIX hydrolase family protein; NUDIX hydrolase 952917..953876 Actinosynnema mirum DSM 43827 8325028 YP_003098673.1 CDS Amir_0866 NC_013093.1 954106 955323 D PFAM: ROK family protein; KEGG: bha:BH1094 transcriptional repressor of the xylose operon; ROK family protein 954106..955323 Actinosynnema mirum DSM 43827 8325029 YP_003098674.1 CDS Amir_0867 NC_013093.1 955320 955928 R PFAM: regulatory protein TetR; KEGG: scl:sce8247 TetR family transcriptional regulator; TetR family transcriptional regulator complement(955320..955928) Actinosynnema mirum DSM 43827 8325030 YP_003098675.1 CDS Amir_0868 NC_013093.1 955999 957054 D PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sus:Acid_6576 amidohydrolase; amidohydrolase 955999..957054 Actinosynnema mirum DSM 43827 8325031 YP_003098676.1 CDS Amir_0869 NC_013093.1 957113 961177 R KEGG: scl:sce2125 hypothetical protein; hypothetical protein complement(957113..961177) Actinosynnema mirum DSM 43827 8325032 YP_003098677.1 CDS Amir_0870 NC_013093.1 961174 962343 R KEGG: afw:Anae109_1073 hypothetical protein; hypothetical protein complement(961174..962343) Actinosynnema mirum DSM 43827 8325033 YP_003098678.1 CDS Amir_0871 NC_013093.1 962346 963824 R KEGG: scl:sce2127 hypothetical protein; hypothetical protein complement(962346..963824) Actinosynnema mirum DSM 43827 8325034 YP_003098679.1 CDS Amir_0872 NC_013093.1 964072 965019 D TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; KEGG: glo:Glov_3553 cobalamin biosynthesis protein CobD; cobalamin biosynthesis protein CobD 964072..965019 Actinosynnema mirum DSM 43827 8325035 YP_003098680.1 CDS Amir_0873 NC_013093.1 965106 965984 R KEGG: bbt:BBta_2034 SURF1 family protein; SURF1 family protein complement(965106..965984) Actinosynnema mirum DSM 43827 8325036 YP_003098681.1 CDS Amir_0874 NC_013093.1 966144 967013 R PFAM: fructosamine kinase; aminoglycoside phosphotransferase; KEGG: hch:HCH_00321 fructosamine-3-kinase; fructosamine kinase complement(966144..967013) Actinosynnema mirum DSM 43827 8325037 YP_003098682.1 CDS Amir_0875 NC_013093.1 967010 967468 R PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; KEGG: rru:Rru_A3646 protein tyrosine phosphatase; protein tyrosine phosphatase complement(967010..967468) Actinosynnema mirum DSM 43827 8325038 YP_003098683.1 CDS Amir_0876 NC_013093.1 967621 968277 D SMART: HNH nuclease; KEGG: ank:AnaeK_4158 HNH nuclease; HNH nuclease 967621..968277 Actinosynnema mirum DSM 43827 8325039 YP_003098684.1 CDS Amir_0877 NC_013093.1 968490 968609 D hypothetical protein 968490..968609 Actinosynnema mirum DSM 43827 8325040 YP_003098685.1 CDS Amir_0878 NC_013093.1 968695 969738 D PFAM: aminotransferase class I and II; KEGG: cko:CKO_02518 threonine-phosphate decarboxylase; class I and II aminotransferase 968695..969738 Actinosynnema mirum DSM 43827 8325041 YP_003098686.1 CDS Amir_0879 NC_013093.1 969735 970877 D PFAM: protein of unknown function DUF34; KEGG: pca:Pcar_2677 hypothetical protein; hypothetical protein 969735..970877 Actinosynnema mirum DSM 43827 8325042 YP_003098687.1 CDS Amir_0880 NC_013093.1 970879 971616 D PFAM: protein of unknown function DUF164; KEGG: wsu:WS2117 hypothetical protein; hypothetical protein 970879..971616 Actinosynnema mirum DSM 43827 8325043 YP_003098688.1 CDS Amir_0881 NC_013093.1 971613 972788 D PFAM: phosphoglycerate mutase; ribonuclease H; KEGG: mxa:MXAN_5728 ribonuclease H; phosphoglycerate mutase 971613..972788 Actinosynnema mirum DSM 43827 8325044 YP_003098689.1 CDS Amir_0882 NC_013093.1 973824 974369 R PFAM: NADPH-dependent FMN reductase; KEGG: cti:RALTA_A1785 NAD(P)H-dependent FMN reductase, sulfate starvation-induced protein; NADPH-dependent FMN reductase complement(973824..974369) Actinosynnema mirum DSM 43827 8325045 YP_003098690.1 CDS Amir_0883 NC_013093.1 975092 975562 R KEGG: hypothetical protein; hypothetical protein complement(975092..975562) Actinosynnema mirum DSM 43827 8325047 YP_003098691.1 CDS Amir_0884 NC_013093.1 975952 976227 D hypothetical protein 975952..976227 Actinosynnema mirum DSM 43827 8325048 YP_003098692.1 CDS Amir_0885 NC_013093.1 976232 976729 D KEGG: GJ12100 gene product from transcript GJ12100- RA; hypothetical protein 976232..976729 Actinosynnema mirum DSM 43827 8325049 YP_003098693.1 CDS Amir_0886 NC_013093.1 976710 979577 D KEGG: bcr:BCAH187_E0044 hypothetical protein; hypothetical protein 976710..979577 Actinosynnema mirum DSM 43827 8325050 YP_003098694.1 CDS Amir_0887 NC_013093.1 979574 981517 D KEGG: ajs:Ajs_4066 single-strand binding protein; hypothetical protein 979574..981517 Actinosynnema mirum DSM 43827 8325051 YP_003098695.1 CDS Amir_0888 NC_013093.1 981517 982155 D KEGG: hypothetical protein; hypothetical protein 981517..982155 Actinosynnema mirum DSM 43827 8325052 YP_003098696.1 CDS Amir_0889 NC_013093.1 982157 983170 D PFAM: NLP/P60 protein; KEGG: gme:Gmet_2365 NLP/P60:sporulation-related protein; NLP/P60 protein 982157..983170 Actinosynnema mirum DSM 43827 8325053 YP_003098697.1 CDS Amir_0890 NC_013093.1 983271 983993 D KEGG: scl:sce1554 prolipoprotein diacylglyceryl transferase; hypothetical protein 983271..983993 Actinosynnema mirum DSM 43827 8325054 YP_003098698.1 CDS Amir_0891 NC_013093.1 984139 984333 D hypothetical protein 984139..984333 Actinosynnema mirum DSM 43827 8325055 YP_003098699.1 CDS Amir_0892 NC_013093.1 984474 985142 D TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; Semialdehyde dehydrogenase NAD - binding; 6- phosphogluconate dehydrogenase NAD-binding; KEGG: oca:OCAR_5001 NADPH-dependent f420 reductase; NADPH-dependent F420 reductase 984474..985142 Actinosynnema mirum DSM 43827 8325056 YP_003098700.1 CDS Amir_0893 NC_013093.1 985142 985897 D KEGG: scl:sce7051 periplasmic substrate- binding protein; periplasmic substrate-binding protein 985142..985897 Actinosynnema mirum DSM 43827 8325057 YP_003098701.1 CDS Amir_0894 NC_013093.1 985902 986837 R KEGG: bte:BTH_II2193 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; proline iminopeptidase complement(985902..986837) Actinosynnema mirum DSM 43827 8325058 YP_003098702.1 CDS Amir_0895 NC_013093.1 986940 988310 D SMART: LamG domain protein jellyroll fold domain protein; KEGG: GK16139 gene product from transcript GK16139- RA; LamG domain-containing protein 986940..988310 Actinosynnema mirum DSM 43827 8325059 YP_003098703.1 CDS Amir_0896 NC_013093.1 988353 989105 R SMART: ATPase AAA; KEGG: rme:Rmet_4896 SMC protein-like protein; ATPase AAA complement(988353..989105) Actinosynnema mirum DSM 43827 8325060 YP_003098704.1 CDS Amir_0898 NC_013093.1 989737 990567 R PFAM: aminoglycoside phosphotransferase; aminoglycoside phosphotransferase complement(989737..990567) Actinosynnema mirum DSM 43827 8325062 YP_003098705.1 CDS Amir_0899 NC_013093.1 990578 991321 R SMART: ATPase AAA; KEGG: rme:Rmet_4896 SMC protein-like protein; ATPase AAA complement(990578..991321) Actinosynnema mirum DSM 43827 8325063 YP_003098706.1 CDS Amir_0900 NC_013093.1 991333 992211 R PFAM: Radical SAM domain protein; KEGG: rpd:RPD_4322 radical SAM family protein; Radical SAM domain-containing protein complement(991333..992211) Actinosynnema mirum DSM 43827 8325064 YP_003098707.1 CDS Amir_0901 NC_013093.1 992208 992489 R hypothetical protein complement(992208..992489) Actinosynnema mirum DSM 43827 8325065 YP_003098708.1 CDS Amir_0902 NC_013093.1 992673 993551 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 992673..993551 Actinosynnema mirum DSM 43827 8325066 YP_003098709.1 CDS Amir_0903 NC_013093.1 993548 993742 D PFAM: protein of unknown function DUF397; hypothetical protein 993548..993742 Actinosynnema mirum DSM 43827 8325067 YP_003098710.1 CDS Amir_0904 NC_013093.1 993815 994678 R KEGG: glo:Glov_0957 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: ketopantoate hydroxymethyltransferase; 3-methyl-2-oxobutanoatehydroxymethyltransferase complement(993815..994678) Actinosynnema mirum DSM 43827 8325068 YP_003098711.1 CDS Amir_0905 NC_013093.1 994858 995433 R KEGG: bmj:BMULJ_04515 predicted hydrolase or acyltransferase; hypothetical protein complement(994858..995433) Actinosynnema mirum DSM 43827 8325069 YP_003098712.1 CDS lysS NC_013093.1 995843 999127 D catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 995843..999127 Actinosynnema mirum DSM 43827 8325070 YP_003098713.1 CDS Amir_0907 NC_013093.1 999230 1000795 R PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: spe:Spro_2416 TAP domain-containing protein; TAP domain-containing protein complement(999230..1000795) Actinosynnema mirum DSM 43827 8325071 YP_003098714.1 CDS Amir_0908 NC_013093.1 1000882 1002597 D KEGG: csa:Csal_0495 NH(3)-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; NAD+ synthetase 1000882..1002597 Actinosynnema mirum DSM 43827 8325072 YP_003098715.1 CDS Amir_0909 NC_013093.1 1002841 1004184 D PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase; glutamine synthetase 1002841..1004184 Actinosynnema mirum DSM 43827 8325073 YP_003098716.1 CDS Amir_0910 NC_013093.1 1004181 1008275 D TIGRFAM: methyltransferase FkbM family; KEGG: pzu:PHZ_c0476 hypothetical protein; methyltransferase 1004181..1008275 Actinosynnema mirum DSM 43827 8325074 YP_003098717.1 CDS Amir_0911 NC_013093.1 1013634 1014770 D PFAM: phosphate transporter; KEGG: glo:Glov_0587 phosphate transporter; phosphate transporter 1013634..1014770 Actinosynnema mirum DSM 43827 8325077 YP_003098718.1 CDS Amir_0912 NC_013093.1 1014767 1014991 D hypothetical protein 1014767..1014991 Actinosynnema mirum DSM 43827 8325078 YP_003098719.1 CDS Amir_0913 NC_013093.1 1015032 1017968 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1015032..1017968 Actinosynnema mirum DSM 43827 8325079 YP_003098720.1 CDS Amir_0914 NC_013093.1 1018102 1018332 R hypothetical protein complement(1018102..1018332) Actinosynnema mirum DSM 43827 8325080 YP_003098721.1 CDS Amir_0915 NC_013093.1 1018522 1019133 D KEGG: sml:Smlt3524 autotransporter subtilisin-like protease; hypothetical protein 1018522..1019133 Actinosynnema mirum DSM 43827 8325081 YP_003098722.1 CDS Amir_0916 NC_013093.1 1019723 1020433 R PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: aha:AHA_2241 HAD family hydrolase; Haloacid dehalogenase domain-containing protein hydrolase complement(1019723..1020433) Actinosynnema mirum DSM 43827 8325082 YP_003098723.1 CDS Amir_0917 NC_013093.1 1020430 1021272 R PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: yen:YE1303 hypothetical protein; GntR family transcriptional regulator complement(1020430..1021272) Actinosynnema mirum DSM 43827 8325083 YP_003098724.1 CDS Amir_0918 NC_013093.1 1021550 1021999 D hypothetical protein 1021550..1021999 Actinosynnema mirum DSM 43827 8325084 YP_003098725.1 CDS Amir_0919 NC_013093.1 1022001 1022285 D hypothetical protein 1022001..1022285 Actinosynnema mirum DSM 43827 8325085 YP_003098726.1 CDS Amir_0920 NC_013093.1 1022282 1022557 D hypothetical protein 1022282..1022557 Actinosynnema mirum DSM 43827 8325086 YP_003098727.1 CDS Amir_0921 NC_013093.1 1022862 1024313 D KEGG: pha:PSHAb0091 cell divisionFtsK/SpoIIIE domain-containing protein; DNA segregation ATPase FtsK/SpoIIIE-like protein 1022862..1024313 Actinosynnema mirum DSM 43827 8325087 YP_003098728.1 CDS Amir_0922 NC_013093.1 1024310 1025893 D hypothetical protein 1024310..1025893 Actinosynnema mirum DSM 43827 8325088 YP_003098729.1 CDS Amir_0923 NC_013093.1 1025910 1026098 D hypothetical protein 1025910..1026098 Actinosynnema mirum DSM 43827 8325089 YP_003098730.1 CDS Amir_0924 NC_013093.1 1026134 1027333 D PFAM: integrase family protein; KEGG: bcb:BCB4264_A2589 DNA integration/recombination/invertion protein; integrase family protein 1026134..1027333 Actinosynnema mirum DSM 43827 8325090 YP_003098731.1 CDS Amir_0925 NC_013093.1 1027480 1028904 R TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: gur:Gura_2228 glutamine synthetase, type I; glutamine synthetase complement(1027480..1028904) Actinosynnema mirum DSM 43827 8325091 YP_003098732.1 CDS Amir_0926 NC_013093.1 1029103 1029576 D PFAM: hypothetical protein; KEGG: shl:Shal_2580 RDD domain-containing protein; hypothetical protein 1029103..1029576 Actinosynnema mirum DSM 43827 8325092 YP_003098733.1 CDS Amir_0927 NC_013093.1 1029691 1030419 R hypothetical protein complement(1029691..1030419) Actinosynnema mirum DSM 43827 8325093 YP_003098734.1 CDS Amir_0928 NC_013093.1 1030491 1033121 D PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; KEGG: bam:Bamb_1322 UvrD/REP helicase; UvrD/REP helicase 1030491..1033121 Actinosynnema mirum DSM 43827 8325094 YP_003098735.1 CDS Amir_0929 NC_013093.1 1033675 1034094 D PFAM: transcription factor WhiB; HMG-I and HMG-Y DNA-binding domain protein; transcription factor WhiB 1033675..1034094 Actinosynnema mirum DSM 43827 8325095 YP_003098736.1 CDS Amir_0930 NC_013093.1 1034091 1034327 D hypothetical protein 1034091..1034327 Actinosynnema mirum DSM 43827 8325096 YP_003098737.1 CDS Amir_0931 NC_013093.1 1034760 1035653 D PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: smt:Smal_2740 ubiquinone biosynthesis O- methyltransferase; type 12 methyltransferase 1034760..1035653 Actinosynnema mirum DSM 43827 8325097 YP_003098738.1 CDS Amir_0933 NC_013093.1 1036103 1036660 R hypothetical protein complement(1036103..1036660) Actinosynnema mirum DSM 43827 8325099 YP_003098739.1 CDS Amir_0934 NC_013093.1 1036772 1038082 R PFAM: ABC-1 domain protein; KEGG: mxa:MXAN_0725 ABC1 domain protein; ABC transporter complement(1036772..1038082) Actinosynnema mirum DSM 43827 8325100 YP_003098740.1 CDS Amir_0935 NC_013093.1 1038592 1039698 R PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ank:AnaeK_3014 UBA/ThiF-type NAD/FAD binding protein; UBA/THIF-type NAD/FAD binding protein complement(1038592..1039698) Actinosynnema mirum DSM 43827 8325101 YP_003098741.1 CDS Amir_0936 NC_013093.1 1039978 1040133 R hypothetical protein complement(1039978..1040133) Actinosynnema mirum DSM 43827 8325102 YP_003098742.1 CDS Amir_0937 NC_013093.1 1040335 1040862 D PFAM: protein of unknown function DUF45; KEGG: gox:GOX1405 hypothetical protein; hypothetical protein 1040335..1040862 Actinosynnema mirum DSM 43827 8325103 YP_003098743.1 CDS Amir_0938 NC_013093.1 1040866 1042308 R KEGG: met:M446_4394 NADH-quinone oxidoreductase, E subunit; hypothetical protein complement(1040866..1042308) Actinosynnema mirum DSM 43827 8325104 YP_003098744.1 CDS Amir_0939 NC_013093.1 1042388 1043548 D PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: bha:BH2586 hypothetical protein; PDZ/DHR/GLGF domain-containing protein 1042388..1043548 Actinosynnema mirum DSM 43827 8325105 YP_003098745.1 CDS Amir_0940 NC_013093.1 1043630 1044172 R hypothetical protein complement(1043630..1044172) Actinosynnema mirum DSM 43827 8325106 YP_003098746.1 CDS Amir_0941 NC_013093.1 1044282 1047287 D PFAM: protein of unknown function UPF0182; KEGG: reh:H16_A1615 hypothetical membrane spanning protein; hypothetical protein 1044282..1047287 Actinosynnema mirum DSM 43827 8325107 YP_003098747.1 CDS Amir_0942 NC_013093.1 1048143 1048343 R hypothetical protein complement(1048143..1048343) Actinosynnema mirum DSM 43827 8325111 YP_003098748.1 CDS Amir_0943 NC_013093.1 1048791 1049291 D PFAM: transcriptional regulator PadR family protein; KEGG: scl:sce6005 transcriptional regulator; PadR family transcriptional regulator 1048791..1049291 Actinosynnema mirum DSM 43827 8325112 YP_003098749.1 CDS Amir_0944 NC_013093.1 1049362 1050465 D TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: gsu:GSU2278 peptide chain release factor 2; peptide chain release factor 2 1049362..1050465 Actinosynnema mirum DSM 43827 8325113 YP_003098750.1 CDS Amir_0945 NC_013093.1 1050653 1051342 D KEGG: bsu:BSU35260 cell-division ATP-binding protein; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter; SMART: ATPase AAA; cell division ATP-binding protein FtsE 1050653..1051342 Actinosynnema mirum DSM 43827 8325114 YP_003098751.1 CDS Amir_0946 NC_013093.1 1051381 1052283 D PFAM: protein of unknown function DUF214; KEGG: ppd:Ppro_2411 hypothetical protein; cell division protein FtsX 1051381..1052283 Actinosynnema mirum DSM 43827 8325115 YP_003098752.1 CDS Amir_0947 NC_013093.1 1052314 1052799 D TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; KEGG: ppd:Ppro_1314 SsrA-binding protein; SsrA-binding protein 1052314..1052799 Actinosynnema mirum DSM 43827 8325116 YP_003098753.1 CDS Amir_0948 NC_013093.1 1052864 1053508 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: tgr:Tgr7_2171 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator complement(1052864..1053508) Actinosynnema mirum DSM 43827 8325117 YP_003098754.1 CDS Amir_0949 NC_013093.1 1053496 1054746 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sus:Acid_2792 PAS/PAC sensor signal transduction histidine kinase; histidine kinase complement(1053496..1054746) Actinosynnema mirum DSM 43827 8325118 YP_003098755.1 CDS Amir_0950 NC_013093.1 1055339 1056070 R hypothetical protein complement(1055339..1056070) Actinosynnema mirum DSM 43827 8325120 YP_003098756.1 CDS Amir_0951 NC_013093.1 1056385 1058703 R KEGG: rce:RC1_1438 ATP-dependent helicase protein, TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; ATP-dependent helicase HrpB complement(1056385..1058703) Actinosynnema mirum DSM 43827 8325121 YP_003098757.1 CDS Amir_0952 NC_013093.1 1058720 1059853 D PFAM: glycosyl transferase family 2; KEGG: gbe:GbCGDNIH1_1979 HpnB protein; family 2 glycosyl transferase 1058720..1059853 Actinosynnema mirum DSM 43827 8325122 YP_003098758.1 CDS Amir_0953 NC_013093.1 1059858 1060682 D PFAM: GCN5-related N-acetyltransferase; KEGG: mlo:mlr0192 hypothetical protein; GCN5-like N-acetyltransferase 1059858..1060682 Actinosynnema mirum DSM 43827 8325123 YP_003098759.1 CDS Amir_0954 NC_013093.1 1060794 1062101 D PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: afw:Anae109_0137 major facilitator transporter; major facilitator superfamily protein 1060794..1062101 Actinosynnema mirum DSM 43827 8325124 YP_003098760.1 CDS Amir_0955 NC_013093.1 1062170 1062934 D KEGG: maq:Maqu_3013 DsbA oxidoreductase; protein-disulfide isomerase-like protein 1062170..1062934 Actinosynnema mirum DSM 43827 8325125 YP_003098761.1 CDS Amir_0956 NC_013093.1 1062951 1064255 R KEGG: dps:DP1266 coenzyme F390 synthetase II; phenylacetate--CoA ligase complement(1062951..1064255) Actinosynnema mirum DSM 43827 8325126 YP_003098762.1 CDS Amir_0957 NC_013093.1 1064749 1066320 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: bsu:BSU15770 protein kinase; serine/threonine protein kinase complement(1064749..1066320) Actinosynnema mirum DSM 43827 8325128 YP_003098763.1 CDS Amir_0958 NC_013093.1 1066453 1069656 R PFAM: protein of unknown function DUF450; SMART: DEAD-like helicase; KEGG: tbd:Tbd_2685 DEAD/DEAH box helicase; hypothetical protein complement(1066453..1069656) Actinosynnema mirum DSM 43827 8325129 YP_003098764.1 CDS Amir_0959 NC_013093.1 1069664 1070992 R PFAM: restriction modification system DNA specificity domain; KEGG: rsh:Rsph17029_1858 restriction modification system DNA specificity subunit; restriction modification system DNA specificity domain-containing protein complement(1069664..1070992) Actinosynnema mirum DSM 43827 8325130 YP_003098765.1 CDS Amir_0960 NC_013093.1 1070989 1073001 R PFAM: N-6 DNA methylase; KEGG: hha:Hhal_1155 N-6 DNA methylase; N-6 DNA methylase complement(1070989..1073001) Actinosynnema mirum DSM 43827 8325131 YP_003098766.1 CDS Amir_0961 NC_013093.1 1073083 1075116 R PFAM: N-6 DNA methylase; RNA methylase; KEGG: bvi:Bcep1808_0009 N-6 DNA methylase; N-6 DNA methylase complement(1073083..1075116) Actinosynnema mirum DSM 43827 8325132 YP_003098767.1 CDS Amir_0963 NC_013093.1 1077307 1078287 D KEGG: hypothetical protein; hypothetical protein 1077307..1078287 Actinosynnema mirum DSM 43827 8325134 YP_003098768.1 CDS Amir_0964 NC_013093.1 1078411 1078551 D hypothetical protein 1078411..1078551 Actinosynnema mirum DSM 43827 8325135 YP_003098769.1 CDS Amir_0965 NC_013093.1 1078583 1079779 R KEGG: rde:RD1_2154 hypothetical protein; hypothetical protein complement(1078583..1079779) Actinosynnema mirum DSM 43827 8325136 YP_003098770.1 CDS Amir_0966 NC_013093.1 1079924 1081480 D PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sus:Acid_4295 response regulator receiver modulated serine phosphatase; protein serine/threonine phosphatase 1079924..1081480 Actinosynnema mirum DSM 43827 8325137 YP_003098771.1 CDS Amir_0967 NC_013093.1 1081477 1082454 D PFAM: cobalamin B12-binding domain protein; KEGG: rpc:RPC_1467 cobalamin B12-binding; cobalamin B12-binding domain-containing protein 1081477..1082454 Actinosynnema mirum DSM 43827 8325138 YP_003098772.1 CDS Amir_0968 NC_013093.1 1082545 1082907 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist; anti-sigma-factor antagonist 1082545..1082907 Actinosynnema mirum DSM 43827 8325139 YP_003098773.1 CDS Amir_0969 NC_013093.1 1082983 1083417 D hypothetical protein 1082983..1083417 Actinosynnema mirum DSM 43827 8325140 YP_003098774.1 CDS Amir_0970 NC_013093.1 1083604 1084890 D PFAM: extracellular solute-binding protein family 1; KEGG: smd:Smed_3329 extracellular solute-binding protein family 1; family 1 extracellular solute-binding protein 1083604..1084890 Actinosynnema mirum DSM 43827 8325141 YP_003098775.1 CDS Amir_0971 NC_013093.1 1084896 1085852 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 1084896..1085852 Actinosynnema mirum DSM 43827 8325142 YP_003098776.1 CDS Amir_0972 NC_013093.1 1085849 1086679 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04137 transport system permease ABC transporter protein; ABC transporter inner membrane protein 1085849..1086679 Actinosynnema mirum DSM 43827 8325143 YP_003098777.1 CDS Amir_0973 NC_013093.1 1086676 1087242 D KEGG: acp:A2cp1_3283 hypothetical protein; hypothetical protein 1086676..1087242 Actinosynnema mirum DSM 43827 8325144 YP_003098778.1 CDS Amir_0974 NC_013093.1 1087260 1087580 D PFAM: protein of unknown function DUF718; KEGG: bcm:Bcenmc03_6232 L-rhamnose 1-epimerase; hypothetical protein 1087260..1087580 Actinosynnema mirum DSM 43827 8325145 YP_003098779.1 CDS Amir_0975 NC_013093.1 1087652 1088668 D PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: aav:Aave_4199 transcriptional regulator, LacI family; LacI family transcriptional regulator 1087652..1088668 Actinosynnema mirum DSM 43827 8325146 YP_003098780.1 CDS Amir_0976 NC_013093.1 1088702 1091029 R PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: helix-turn-helix domain protein; hypothetical protein; KEGG: scl:sce6858 hypothetical protein; XRE family transcriptional regulator complement(1088702..1091029) Actinosynnema mirum DSM 43827 8325147 YP_003098781.1 CDS Amir_0977 NC_013093.1 1091435 1093690 D PFAM: terpene synthase; KEGG: mxa:MXAN_6247 terpene synthase, metal binding domain protein; terpene synthase 1091435..1093690 Actinosynnema mirum DSM 43827 8325148 YP_003098782.1 CDS Amir_0978 NC_013093.1 1093751 1094320 R PFAM: NUDIX hydrolase; KEGG: oan:Oant_4146 NUDIX hydrolase; NUDIX hydrolase complement(1093751..1094320) Actinosynnema mirum DSM 43827 8325149 YP_003098783.1 CDS Amir_0979 NC_013093.1 1094454 1094558 R hypothetical protein complement(1094454..1094558) Actinosynnema mirum DSM 43827 8325150 YP_003098784.1 CDS Amir_0980 NC_013093.1 1094654 1095991 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: afw:Anae109_0769 heat shock protein DnaJ domain-containing protein; XRE family transcriptional regulator complement(1094654..1095991) Actinosynnema mirum DSM 43827 8325151 YP_003098785.1 CDS Amir_0982 NC_013093.1 1096592 1097392 R KEGG: scl:sce6462 hypothetical protein; hypothetical protein complement(1096592..1097392) Actinosynnema mirum DSM 43827 8325153 YP_003098786.1 CDS Amir_0983 NC_013093.1 1097714 1098841 D PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: azc:AZC_3175 FMNH2-dependent monooxygenase; acyl-CoA dehydrogenase type 2 domain-containing protein 1097714..1098841 Actinosynnema mirum DSM 43827 8325154 YP_003098787.1 CDS Amir_0984 NC_013093.1 1098842 1099873 D KEGG: aba:Acid345_1175 translation initiation factor 2B subunit I family (IF-2BI); TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; eIF-2B alpha/beta/delta-like protein 1098842..1099873 Actinosynnema mirum DSM 43827 8325155 YP_003098788.1 CDS Amir_0985 NC_013093.1 1099866 1100540 D TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tgr:Tgr7_2625 2,3-diketo-5-methylthio-1- phosphopentane phosphatase; 2, 3-diketo-5-methylthio-1-phosphopentanephosphatase 1099866..1100540 Actinosynnema mirum DSM 43827 8325156 YP_003098789.1 CDS Amir_0986 NC_013093.1 1100537 1101157 D TIGRFAM: methylthioribulose-1-phosphate dehydratase; PFAM: class II aldolase/adducin family protein; KEGG: tgr:Tgr7_2623 methylthioribulose-1-phosphate dehydratase; methylthioribulose-1-phosphate dehydratase 1100537..1101157 Actinosynnema mirum DSM 43827 8325157 YP_003098790.1 CDS Amir_0987 NC_013093.1 1101154 1101723 D PFAM: acireductone dioxygenase ARD; KEGG: tgr:Tgr7_2624 acireductone dioxygenase ARD; acireductone dioxygenase ARD 1101154..1101723 Actinosynnema mirum DSM 43827 8325158 YP_003098791.1 CDS Amir_0988 NC_013093.1 1101756 1102631 R PFAM: aminoglycoside phosphotransferase; KEGG: cvi:CV_1007 serine/threonine protein kinase; aminoglycoside phosphotransferase complement(1101756..1102631) Actinosynnema mirum DSM 43827 8325159 YP_003098792.1 CDS Amir_0989 NC_013093.1 1103164 1104954 D KEGG: bha:BH2614 cytochrome Caa3 oxidase (subunit I); TIGRFAM: cytochrome C oxidase, subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase, subunit I 1103164..1104954 Actinosynnema mirum DSM 43827 8325160 YP_003098793.1 CDS Amir_0990 NC_013093.1 1105046 1106266 D KEGG: scl:sce0663 hypothetical protein; TIGRFAM: phosphoserine phosphatase SerB; HAD- superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein; phosphoserine phosphatase SerB 1105046..1106266 Actinosynnema mirum DSM 43827 8325161 YP_003098794.1 CDS Amir_0991 NC_013093.1 1106263 1107048 D PFAM: protein of unknown function UPF0099; KEGG: predicted protein; K04794 peptidyl-tRNA hydrolase, PTH2 family; hypothetical protein 1106263..1107048 Actinosynnema mirum DSM 43827 8325162 YP_003098795.1 CDS Amir_0992 NC_013093.1 1108027 1108824 D hypothetical protein 1108027..1108824 Actinosynnema mirum DSM 43827 8325163 YP_003098796.1 CDS Amir_0994 NC_013093.1 1109105 1110517 D KEGG: phospholipase/phosphatidylserine synthase; PFAM: phospholipase D/transphosphatidylase; SMART: phospholipase D/transphosphatidylase; phospholipase D 1109105..1110517 Actinosynnema mirum DSM 43827 8325165 YP_003098797.1 CDS Amir_0995 NC_013093.1 1110535 1112580 R SMART: helicase c2; DEAD-like helicase; KEGG: mxa:MXAN_6717 ATP-dependent helicase; helicase c2 complement(1110535..1112580) Actinosynnema mirum DSM 43827 8325166 YP_003098798.1 CDS Amir_0996 NC_013093.1 1112737 1113312 R PFAM: BioY protein; KEGG: mxa:MXAN_2207 BioY family protein; BioY protein complement(1112737..1113312) Actinosynnema mirum DSM 43827 8325167 YP_003098799.1 CDS Amir_0997 NC_013093.1 1113448 1114800 R KEGG: cak:Caul_0228 polysaccharide deacetylase; cell wall biogenesis glycosyltransferase complement(1113448..1114800) Actinosynnema mirum DSM 43827 8325168 YP_003098800.1 CDS Amir_0998 NC_013093.1 1114797 1115312 R hypothetical protein complement(1114797..1115312) Actinosynnema mirum DSM 43827 8325169 YP_003098801.1 CDS Amir_0999 NC_013093.1 1115593 1116381 D KEGG: ect:ECIAI39_4258 invasin/intimin protein; hypothetical protein 1115593..1116381 Actinosynnema mirum DSM 43827 8325170 YP_003098802.1 CDS Amir_1000 NC_013093.1 1116378 1116551 D TIGRFAM: LPXTG-motif cell wall anchor domain protein; LPXTG-motif cell wall anchor domain-containing protein 1116378..1116551 Actinosynnema mirum DSM 43827 8325171 YP_003098803.1 CDS Amir_1001 NC_013093.1 1116623 1117795 D KEGG: rso:RSp0510 UDP-N-acetylglucosamine 2- epimerase protein; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 1116623..1117795 Actinosynnema mirum DSM 43827 8325172 YP_003098804.1 CDS Amir_1002 NC_013093.1 1117922 1118578 D hypothetical protein 1117922..1118578 Actinosynnema mirum DSM 43827 8325173 YP_003098805.1 CDS Amir_1003 NC_013093.1 1118721 1119290 R PFAM: isochorismatase hydrolase; KEGG: sme:SMc02275 pyrazinamidase/nicotinamidase (includes: pyrazinamidase, nicotinamidase) protein; isochorismatase hydrolase complement(1118721..1119290) Actinosynnema mirum DSM 43827 8325174 YP_003098806.1 CDS Amir_1004 NC_013093.1 1119301 1120614 R TIGRFAM: nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; KEGG: rpi:Rpic_4654 nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase complement(1119301..1120614) Actinosynnema mirum DSM 43827 8325175 YP_003098807.1 CDS Amir_1005 NC_013093.1 1120667 1120966 D PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: bbr:BB2017 ATP-dependent Clp protease adaptor protein ClpS; ATP-dependent Clp protease adaptor protein ClpS 1120667..1120966 Actinosynnema mirum DSM 43827 8325176 YP_003098808.1 CDS Amir_1006 NC_013093.1 1120963 1121520 D hypothetical protein 1120963..1121520 Actinosynnema mirum DSM 43827 8325177 YP_003098809.1 CDS Amir_1007 NC_013093.1 1121517 1122131 D KEGG: aav:Aave_1804 peptidase S58, DmpA; peptidase S58, DmpA 1121517..1122131 Actinosynnema mirum DSM 43827 8325178 YP_003098810.1 CDS Amir_1008 NC_013093.1 1122293 1122862 D KEGG: scl:sce7049 hypothetical protein; hypothetical protein 1122293..1122862 Actinosynnema mirum DSM 43827 8325179 YP_003098811.1 CDS Amir_1009 NC_013093.1 1122872 1123327 D PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: nmu:Nmul_A0971 Mov34/MPN/PAD-1; Mov34/MPN/PAD-1 family protein 1122872..1123327 Actinosynnema mirum DSM 43827 8325180 YP_003098812.1 CDS Amir_1010 NC_013093.1 1123390 1123662 D PFAM: thiamineS protein; KEGG: hch:HCH_02849 molybdopterin converting factor, small subunit; sulfur carrier protein ThiS 1123390..1123662 Actinosynnema mirum DSM 43827 8325181 YP_003098813.1 CDS Amir_1011 NC_013093.1 1123670 1124620 D TIGRFAM: cysteine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: reh:H16_A0807 cysteine synthase; cysteine synthase 1123670..1124620 Actinosynnema mirum DSM 43827 8325182 YP_003098814.1 CDS Amir_1012 NC_013093.1 1125224 1125994 D PFAM: beta-lactamase domain protein; KEGG: bcr:BCAH187_A1247 metallo-beta-lactamase family protein; beta-lactamase domain-containing protein 1125224..1125994 Actinosynnema mirum DSM 43827 8325183 YP_003098815.1 CDS Amir_1013 NC_013093.1 1126035 1126871 R PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: sal:Sala_3160 senescence marker protein-30 (SMP-30); SMP-30/Gluconolaconase/LRE domain-containing protein complement(1126035..1126871) Actinosynnema mirum DSM 43827 8325184 YP_003098816.1 CDS Amir_1014 NC_013093.1 1127087 1127722 D PFAM: rhomboid family protein; KEGG: amc:MADE_01334 rhomboid-like protein; rhomboid family protein 1127087..1127722 Actinosynnema mirum DSM 43827 8325185 YP_003098817.1 CDS Amir_1015 NC_013093.1 1127719 1128513 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1127719..1128513 Actinosynnema mirum DSM 43827 8325186 YP_003098818.1 CDS Amir_1016 NC_013093.1 1128531 1129343 D PFAM: beta-lactamase domain protein; KEGG: dal:Dalk_3435 beta-lactamase domain protein; beta-lactamase domain-containing protein 1128531..1129343 Actinosynnema mirum DSM 43827 8325187 YP_003098819.1 CDS Amir_1017 NC_013093.1 1129333 1129836 D PFAM: Hemerythrin HHE cation binding domain protein; KEGG: scl:sce7477 hypothetical protein; Hemerythrin HHE cation binding domain-containing protein 1129333..1129836 Actinosynnema mirum DSM 43827 8325188 YP_003098820.1 CDS Amir_1018 NC_013093.1 1129893 1130321 D PFAM: OsmC family protein; KEGG: mxa:MXAN_2740 OsmC/Ohr family protein; OsmC family protein 1129893..1130321 Actinosynnema mirum DSM 43827 8325189 YP_003098821.1 CDS Amir_1019 NC_013093.1 1130397 1130933 R KEGG: afw:Anae109_3915 hypothetical protein; hypothetical protein complement(1130397..1130933) Actinosynnema mirum DSM 43827 8325190 YP_003098822.1 CDS rph NC_013093.1 1130987 1131751 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1130987..1131751 Actinosynnema mirum DSM 43827 8325191 YP_003098823.1 CDS Amir_1021 NC_013093.1 1131748 1132344 D TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein; KEGG: dds:Ddes_1892 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 1131748..1132344 Actinosynnema mirum DSM 43827 8325192 YP_003098824.1 CDS Amir_1022 NC_013093.1 1132329 1133312 R KEGG: bph:Bphy_3741 hypothetical protein; hypothetical protein complement(1132329..1133312) Actinosynnema mirum DSM 43827 8325193 YP_003098825.1 CDS Amir_1023 NC_013093.1 1133344 1133817 R PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: yen:YE1135 thioredoxin-dependent thiol peroxidase; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen complement(1133344..1133817) Actinosynnema mirum DSM 43827 8325194 YP_003098826.1 CDS Amir_1024 NC_013093.1 1133839 1134366 R KEGG: aba:Acid345_1279 hypothetical protein; hypothetical protein complement(1133839..1134366) Actinosynnema mirum DSM 43827 8325195 YP_003098827.1 CDS Amir_1025 NC_013093.1 1134651 1135673 R PFAM: luciferase-like monooxygenase; KEGG: bvi:Bcep1808_1087 luciferase family protein; luciferase-like monooxygenase complement(1134651..1135673) Actinosynnema mirum DSM 43827 8325196 YP_003098828.1 CDS Amir_1026 NC_013093.1 1135785 1136843 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: oan:Oant_2127 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1135785..1136843 Actinosynnema mirum DSM 43827 8325197 YP_003098829.1 CDS Amir_1027 NC_013093.1 1137043 1138020 R PFAM: hypothetical protein; KEGG: pde:Pden_3867 DedA family protein; hypothetical protein complement(1137043..1138020) Actinosynnema mirum DSM 43827 8325198 YP_003098830.1 CDS Amir_1028 NC_013093.1 1138127 1139095 D PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: vvu:VV1_0002 GTPase; cobalamin synthesis protein P47K 1138127..1139095 Actinosynnema mirum DSM 43827 8325199 YP_003098831.1 CDS Amir_1029 NC_013093.1 1139490 1139711 D hypothetical protein 1139490..1139711 Actinosynnema mirum DSM 43827 8325201 YP_003098832.1 CDS Amir_1030 NC_013093.1 1139765 1140379 R PFAM: regulatory protein TetR; KEGG: bat:BAS3063 TetR family transcriptional regulator; TetR family transcriptional regulator complement(1139765..1140379) Actinosynnema mirum DSM 43827 8325202 YP_003098833.1 CDS Amir_1031 NC_013093.1 1140617 1141555 D PFAM: esterase; KEGG: mxa:MXAN_4935 esterase; esterase 1140617..1141555 Actinosynnema mirum DSM 43827 8325203 YP_003098834.1 CDS Amir_1032 NC_013093.1 1141662 1142696 D PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: rso:RSc0624 zinc-dependent alcohol dehydrogenase oxidoreductase protein; alcohol dehydrogenase GroES domain-containing protein 1141662..1142696 Actinosynnema mirum DSM 43827 8325204 YP_003098835.1 CDS Amir_1033 NC_013093.1 1142764 1143471 R PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: rsh:Rsph17029_3564 cobyric acid synthase; CobB/CobQ domain-containing protein glutamine amidotransferase complement(1142764..1143471) Actinosynnema mirum DSM 43827 8325205 YP_003098836.1 CDS Amir_1034 NC_013093.1 1143461 1144645 R PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; KEGG: ilo:IL0432 UDP-N-acetylmuramyl pentapeptide synthase; hypothetical protein complement(1143461..1144645) Actinosynnema mirum DSM 43827 8325206 YP_003098837.1 CDS Amir_1035 NC_013093.1 1144758 1145237 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: reu:Reut_A1326 anaerobic benzoate catabolism transcriptional regulator; XRE family transcriptional regulator complement(1144758..1145237) Actinosynnema mirum DSM 43827 8325207 YP_003098838.1 CDS Amir_1036 NC_013093.1 1145358 1146104 R PFAM: protein of unknown function DUF218; KEGG: mxa:MXAN_6927 SanA protein; hypothetical protein complement(1145358..1146104) Actinosynnema mirum DSM 43827 8325208 YP_003098839.1 CDS Amir_1037 NC_013093.1 1146600 1148798 R TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bce:BC5265 membrane-bound transcriptional regulator LytR; cell envelope-related transcriptional attenuator complement(1146600..1148798) Actinosynnema mirum DSM 43827 8325209 YP_003098840.1 CDS Amir_1038 NC_013093.1 1148989 1151952 D KEGG: hypothetical protein; K01878 glycyl-tRNA synthetase alpha chain; TIGRFAM: glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit; glycyl- tRNA synthetase beta subunit; glycyl-tRNA synthetase subunit beta 1148989..1151952 Actinosynnema mirum DSM 43827 8325210 YP_003098841.1 CDS Amir_1039 NC_013093.1 1152123 1153850 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: hypothetical protein; peptidase S8/S53 subtilisin kexin sedolisin complement(1152123..1153850) Actinosynnema mirum DSM 43827 8325211 YP_003098842.1 CDS Amir_1040 NC_013093.1 1154158 1155252 D KEGG: rpi:Rpic_4074 D-xylose ABC transporter, periplasmic substrate-binding protein; Monosaccharide-transporting ATPase 1154158..1155252 Actinosynnema mirum DSM 43827 8325212 YP_003098843.1 CDS Amir_1041 NC_013093.1 1155319 1156041 R KEGG: aba:Acid345_1276 hypothetical protein; hypothetical protein complement(1155319..1156041) Actinosynnema mirum DSM 43827 8325213 YP_003098844.1 CDS Amir_1042 NC_013093.1 1156638 1156844 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mpt:Mpe_A2202 cold-shock DNA-binding protein family protein; cold-shock DNA-binding domain-containing protein 1156638..1156844 Actinosynnema mirum DSM 43827 8325214 YP_003098845.1 CDS Amir_1043 NC_013093.1 1156980 1157357 R KEGG: cak:Caul_1308 hypothetical protein; hypothetical protein complement(1156980..1157357) Actinosynnema mirum DSM 43827 8325215 YP_003098846.1 CDS Amir_1044 NC_013093.1 1157476 1159557 R KEGG: aba:Acid345_1677 alpha-galactosidase; PFAM: glycosyl hydrolase family 98 carbohydrate binding module; glycoside hydrolase clan GH- D; SMART: glycosyl hydrolase family 98 carbohydrate binding module; alpha-galactosidase complement(1157476..1159557) Actinosynnema mirum DSM 43827 8325216 YP_003098847.1 CDS Amir_1045 NC_013093.1 1159759 1161522 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: sse:Ssed_3347 acyl-CoA dehydrogenase-like protein; acyl-CoA dehydrogenase domain-containing protein complement(1159759..1161522) Actinosynnema mirum DSM 43827 8325217 YP_003098848.1 CDS Amir_1046 NC_013093.1 1161519 1162505 R PFAM: hypothetical protein; KEGG: mxa:MXAN_7273 SWIM zinc finger domain protein; hypothetical protein complement(1161519..1162505) Actinosynnema mirum DSM 43827 8325218 YP_003098849.1 CDS Amir_1047 NC_013093.1 1162498 1165584 R KEGG: scl:sce3369 SWF/SNF family helicase; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; Non-specific serine/threonine protein kinase complement(1162498..1165584) Actinosynnema mirum DSM 43827 8325219 YP_003098850.1 CDS Amir_1048 NC_013093.1 1166313 1166585 R KEGG: gbm:Gbem_1481 transglycosylase-associated protein; hypothetical protein complement(1166313..1166585) Actinosynnema mirum DSM 43827 8325220 YP_003098851.1 CDS Amir_1049 NC_013093.1 1166674 1167405 R KEGG: Hypothetical protein CBG18987; hypothetical protein complement(1166674..1167405) Actinosynnema mirum DSM 43827 8325221 YP_003098852.1 CDS Amir_1050 NC_013093.1 1167448 1168533 R TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: sfu:Sfum_2797 DNA-cytosine methyltransferase; DNA-cytosine methyltransferase complement(1167448..1168533) Actinosynnema mirum DSM 43827 8325222 YP_003098853.1 CDS Amir_1051 NC_013093.1 1168548 1168973 R TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr; KEGG: ajs:Ajs_2197 very short patch repair protein; DNA mismatch endonuclease Vsr complement(1168548..1168973) Actinosynnema mirum DSM 43827 8325223 YP_003098854.1 CDS Amir_1052 NC_013093.1 1169035 1170150 R KEGG: scl:sce2746 protein kinase; hypothetical protein complement(1169035..1170150) Actinosynnema mirum DSM 43827 8325224 YP_003098855.1 CDS Amir_1053 NC_013093.1 1170229 1170900 D hypothetical protein 1170229..1170900 Actinosynnema mirum DSM 43827 8325225 YP_003098856.1 CDS Amir_1054 NC_013093.1 1171277 1172479 D PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mca:MCA1018 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 1171277..1172479 Actinosynnema mirum DSM 43827 8325227 YP_003098857.1 CDS Amir_1055 NC_013093.1 1172496 1174124 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ank:AnaeK_1721 ABC transporter-related protein; ABC transporter complement(1172496..1174124) Actinosynnema mirum DSM 43827 8325228 YP_003098858.1 CDS Amir_1056 NC_013093.1 1174327 1174953 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(1174327..1174953) Actinosynnema mirum DSM 43827 8325230 YP_003098859.1 CDS Amir_1057 NC_013093.1 1175057 1176331 R PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_0079 major facilitator transporter; major facilitator superfamily protein complement(1175057..1176331) Actinosynnema mirum DSM 43827 8325231 YP_003098860.1 CDS Amir_1058 NC_013093.1 1176403 1177371 D PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bac:BamMC406_2532 AraC family transcriptional regulator; AraC family transcriptional regulator 1176403..1177371 Actinosynnema mirum DSM 43827 8325232 YP_003098861.1 CDS Amir_1059 NC_013093.1 1177470 1178231 D PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: cak:Caul_0312 DeoR family transcriptional regulator; DeoR family transcriptional regulator 1177470..1178231 Actinosynnema mirum DSM 43827 8325233 YP_003098862.1 CDS Amir_1060 NC_013093.1 1178228 1179154 D TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: gbm:Gbem_3234 1-phosphofructokinase; 1-phosphofructokinase 1178228..1179154 Actinosynnema mirum DSM 43827 8325234 YP_003098863.1 CDS Amir_1061 NC_013093.1 1179151 1179600 D TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: vco:VC0395_A1421 PTS system, fructose- specific IIABC component; PTS IIA-like nitrogen-regulatory protein PtsN 1179151..1179600 Actinosynnema mirum DSM 43827 8325235 YP_003098864.1 CDS Amir_1062 NC_013093.1 1179597 1181030 D TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; KEGG: rsh:Rsph17029_0435 PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIC subunit 1179597..1181030 Actinosynnema mirum DSM 43827 8325236 YP_003098865.1 CDS Amir_1063 NC_013093.1 1181005 1182555 R PFAM: membrane-flanked domain; KEGG: bha:BH1721 hypothetical protein; membrane-flanked domain-containing protein complement(1181005..1182555) Actinosynnema mirum DSM 43827 8325237 YP_003098866.1 CDS Amir_1064 NC_013093.1 1182648 1183133 R PFAM: membrane-flanked domain; KEGG: bsu:BSU04590 hypothetical protein; membrane-flanked domain-containing protein complement(1182648..1183133) Actinosynnema mirum DSM 43827 8325238 YP_003098867.1 CDS Amir_1065 NC_013093.1 1183207 1183359 R hypothetical protein complement(1183207..1183359) Actinosynnema mirum DSM 43827 8325239 YP_003098868.1 CDS Amir_1066 NC_013093.1 1183493 1185175 R PFAM: AMP-dependent synthetase and ligase; KEGG: bur:Bcep18194_C6898 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase complement(1183493..1185175) Actinosynnema mirum DSM 43827 8325240 YP_003098869.1 CDS Amir_1067 NC_013093.1 1185217 1185420 R hypothetical protein complement(1185217..1185420) Actinosynnema mirum DSM 43827 8325241 YP_003098870.1 CDS Amir_1068 NC_013093.1 1185734 1186228 R PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: atc:AGR_C_466 hypothetical protein; MarR family transcriptional regulator complement(1185734..1186228) Actinosynnema mirum DSM 43827 8325242 YP_003098871.1 CDS Amir_1069 NC_013093.1 1186316 1186921 D PFAM: NAD(P)H dehydrogenase (quinone); NADPH- dependent FMN reductase; KEGG: pmy:Pmen_1298 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 1186316..1186921 Actinosynnema mirum DSM 43827 8325243 YP_003098872.1 CDS Amir_1070 NC_013093.1 1187090 1188232 D KEGG: CG13731; hypothetical protein 1187090..1188232 Actinosynnema mirum DSM 43827 8325244 YP_003098873.1 CDS Amir_1071 NC_013093.1 1188362 1189357 D PFAM: hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: bcm:Bcenmc03_0217 hypothetical protein; hypothetical protein 1188362..1189357 Actinosynnema mirum DSM 43827 8325245 YP_003098874.1 CDS Amir_1072 NC_013093.1 1189746 1190081 D hypothetical protein 1189746..1190081 Actinosynnema mirum DSM 43827 8325246 YP_003098875.1 CDS Amir_1073 NC_013093.1 1190138 1192399 D part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1190138..1192399 Actinosynnema mirum DSM 43827 8325247 YP_003098876.1 CDS Amir_1074 NC_013093.1 1192627 1193808 D PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: hypothetical protein; K00101 L-lactate dehydrogenase (cytochrome); Lactate 2-monooxygenase 1192627..1193808 Actinosynnema mirum DSM 43827 8325248 YP_003098877.1 CDS Amir_1075 NC_013093.1 1193875 1194735 D KEGG: bha:BH1891 hypothetical protein; hypothetical protein 1193875..1194735 Actinosynnema mirum DSM 43827 8325249 YP_003098878.1 CDS Amir_1076 NC_013093.1 1194739 1195434 R SMART: helix-turn-helix- domain containing protein AraC type; KEGG: xca:xccb100_0257 transcriptional regulator, AraC family; AraC family transcriptional regulator complement(1194739..1195434) Actinosynnema mirum DSM 43827 8325250 YP_003098879.1 CDS Amir_1077 NC_013093.1 1195471 1196865 R PFAM: carbohydrate binding family 6; glycoside hydrolase family 16; SMART: cellulose binding type IV; KEGG: hypothetical protein; carbohydrate binding family 6 complement(1195471..1196865) Actinosynnema mirum DSM 43827 8325251 YP_003098880.1 CDS Amir_1078 NC_013093.1 1197132 1198799 R PFAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase; KEGG: hha:Hhal_2421 DNA polymerase I; DNA-directed DNA polymerase complement(1197132..1198799) Actinosynnema mirum DSM 43827 8325252 YP_003098881.1 CDS Amir_1079 NC_013093.1 1198874 1201366 D PFAM: hypothetical protein; KEGG: bid:Bind_1912 hypothetical protein; hypothetical protein 1198874..1201366 Actinosynnema mirum DSM 43827 8325253 YP_003098882.1 CDS Amir_1080 NC_013093.1 1201368 1202015 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: smd:Smed_6054 methyltransferase type 11; type 11 methyltransferase complement(1201368..1202015) Actinosynnema mirum DSM 43827 8325254 YP_003098883.1 CDS Amir_1081 NC_013093.1 1202225 1203148 R PFAM: proline dehydrogenase; KEGG: mxa:MXAN_7405 proline dehydrogenase; proline dehydrogenase complement(1202225..1203148) Actinosynnema mirum DSM 43827 8325255 YP_003098884.1 CDS Amir_1082 NC_013093.1 1203152 1204780 R TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: scl:sce4459 1-pyrroline-5-carboxylate dehydrogenase; delta-1-pyrroline-5-carboxylate dehydrogenase complement(1203152..1204780) Actinosynnema mirum DSM 43827 8325256 YP_003098885.1 CDS Amir_1083 NC_013093.1 1204900 1206438 D KEGG: bha:BH1072 hypothetical protein; PucR family transcriptional regulator 1204900..1206438 Actinosynnema mirum DSM 43827 8325257 YP_003098886.1 CDS Amir_1084 NC_013093.1 1206473 1207273 R PFAM: 60 kDa inner membrane insertion protein; KEGG: gox:GOX1827 inner membrane protein translocase component YidC; 60 kDa inner membrane insertion protein complement(1206473..1207273) Actinosynnema mirum DSM 43827 8325258 YP_003098887.1 CDS Amir_1085 NC_013093.1 1207310 1207588 R hypothetical protein complement(1207310..1207588) Actinosynnema mirum DSM 43827 8325259 YP_003098888.1 CDS Amir_1086 NC_013093.1 1207604 1208224 R KEGG: bbt:BBta_0026 uridine kinase; hypothetical protein complement(1207604..1208224) Actinosynnema mirum DSM 43827 8325260 YP_003098889.1 CDS Amir_1087 NC_013093.1 1208249 1208848 R PFAM: protein of unknown function DUF402; hypothetical protein complement(1208249..1208848) Actinosynnema mirum DSM 43827 8325261 YP_003098890.1 CDS Amir_1088 NC_013093.1 1208870 1210285 R PFAM: GAF domain protein; transcriptional regulator domain protein; KEGG: rme:Rmet_4104 sigma54 specific transcriptional regulator with GAF sensor, fis family; phytochrome sensor protein complement(1208870..1210285) Actinosynnema mirum DSM 43827 8325262 YP_003098891.1 CDS Amir_1089 NC_013093.1 1210449 1211972 D PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_5040 aldehyde dehydrogenase family protein; aldehyde dehydrogenase 1210449..1211972 Actinosynnema mirum DSM 43827 8325263 YP_003098892.1 CDS Amir_1090 NC_013093.1 1211972 1212346 D PFAM: protein of unknown function DUF779; KEGG: mxa:MXAN_5039 hypothetical protein; hypothetical protein 1211972..1212346 Actinosynnema mirum DSM 43827 8325264 YP_003098893.1 CDS Amir_1091 NC_013093.1 1212320 1213867 R PFAM: glycoside hydrolase, family 20, catalytic core; KEGG: cak:Caul_0293 beta-N-acetylhexosaminidase; beta-N-acetylhexosaminidase complement(1212320..1213867) Actinosynnema mirum DSM 43827 8325265 YP_003098894.1 CDS Amir_1092 NC_013093.1 1213908 1215395 R PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: reh:H16_B1017 protein of the adenylate cyclase family; CHAD domain containing protein complement(1213908..1215395) Actinosynnema mirum DSM 43827 8325266 YP_003098895.1 CDS Amir_1093 NC_013093.1 1215543 1216364 D KEGG: mxa:MXAN_2991 adventurous gliding motility protein AglZ; hypothetical protein 1215543..1216364 Actinosynnema mirum DSM 43827 8325267 YP_003098896.1 CDS Amir_1094 NC_013093.1 1216612 1217259 R KEGG: hypothetical protein; hypothetical protein complement(1216612..1217259) Actinosynnema mirum DSM 43827 8325268 YP_003098897.1 CDS Amir_1095 NC_013093.1 1217352 1218302 R PFAM: formyl transferase domain protein; KEGG: kpe:KPK_0268 UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; formyl transferase domain-containing protein complement(1217352..1218302) Actinosynnema mirum DSM 43827 8325269 YP_003098898.1 CDS Amir_1096 NC_013093.1 1218379 1219956 D PFAM: Amidohydrolase 3; amidohydrolase; KEGG: smd:Smed_5168 amidohydrolase 3; amidohydrolase 1218379..1219956 Actinosynnema mirum DSM 43827 8325270 YP_003098899.1 CDS Amir_1097 NC_013093.1 1220228 1220836 R KEGG: scl:sce4531 hypothetical protein; hypothetical protein complement(1220228..1220836) Actinosynnema mirum DSM 43827 8325271 YP_003098900.1 CDS Amir_1098 NC_013093.1 1221425 1222042 D PFAM: peptidase S14 ClpP; KEGG: dal:Dalk_1458 ATP-dependent Clp protease, proteolytic subunit ClpP; endopeptidase Clp 1221425..1222042 Actinosynnema mirum DSM 43827 8325272 YP_003098901.1 CDS Amir_1099 NC_013093.1 1222098 1222727 D PFAM: peptidase S14 ClpP; KEGG: pmu:PM1976 ATP-dependent Clp protease proteolytic subunit; endopeptidase Clp 1222098..1222727 Actinosynnema mirum DSM 43827 8325273 YP_003098902.1 CDS Amir_1100 NC_013093.1 1223191 1223283 D hypothetical protein 1223191..1223283 Actinosynnema mirum DSM 43827 8325274 YP_003098903.1 CDS Amir_1101 NC_013093.1 1223787 1225103 D PFAM: filamentation induced by cAMP protein Fic; KEGG: pol:Bpro_0315 filamentation induced by cAMP protein Fic; filamentation induced by cAMP protein Fic 1223787..1225103 Actinosynnema mirum DSM 43827 8325275 YP_003098904.1 CDS Amir_1102 NC_013093.1 1225890 1227101 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: gur:Gura_1136 helix-turn-helix domain- containing protein; XRE family transcriptional regulator complement(1225890..1227101) Actinosynnema mirum DSM 43827 8325276 YP_003098905.1 CDS Amir_1103 NC_013093.1 1227118 1227627 R PFAM: NUDIX hydrolase; KEGG: bba:Bd2755 ATP/GTP-binding protein; NUDIX hydrolase complement(1227118..1227627) Actinosynnema mirum DSM 43827 8325277 YP_003098906.1 CDS Amir_1104 NC_013093.1 1227842 1228081 D hypothetical protein 1227842..1228081 Actinosynnema mirum DSM 43827 8325278 YP_003098907.1 CDS Amir_1105 NC_013093.1 1228087 1228410 D hypothetical protein 1228087..1228410 Actinosynnema mirum DSM 43827 8325279 YP_003098908.1 CDS Amir_1106 NC_013093.1 1228442 1229353 D PFAM: aminoglycoside phosphotransferase; KEGG: sal:Sala_1765 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 1228442..1229353 Actinosynnema mirum DSM 43827 8325280 YP_003098909.1 CDS Amir_1107 NC_013093.1 1229350 1230756 R KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein complement(1229350..1230756) Actinosynnema mirum DSM 43827 8325281 YP_003098910.1 CDS Amir_1108 NC_013093.1 1230943 1231323 R PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dac:Daci_0148 histidine utilization repressor; GntR family transcriptional regulator complement(1230943..1231323) Actinosynnema mirum DSM 43827 8325282 YP_003098911.1 CDS Amir_1109 NC_013093.1 1231458 1231850 D hypothetical protein 1231458..1231850 Actinosynnema mirum DSM 43827 8325283 YP_003098912.1 CDS Amir_1110 NC_013093.1 1232060 1232389 D hypothetical protein 1232060..1232389 Actinosynnema mirum DSM 43827 8325284 YP_003098913.1 CDS Amir_1111 NC_013093.1 1232386 1232634 D hypothetical protein 1232386..1232634 Actinosynnema mirum DSM 43827 8325285 YP_003098914.1 CDS Amir_1112 NC_013093.1 1232640 1232849 D hypothetical protein 1232640..1232849 Actinosynnema mirum DSM 43827 8325286 YP_003098915.1 CDS Amir_1113 NC_013093.1 1232929 1234311 D PFAM: cell divisionFtsK/SpoIIIE; KEGG: abu:Abu_1159 cell division protein FtsK; cell division protein FtsK/SpoIIIE 1232929..1234311 Actinosynnema mirum DSM 43827 8325287 YP_003098916.1 CDS Amir_1114 NC_013093.1 1234308 1234730 D PFAM: transcription factor WhiB; transcription factor WhiB 1234308..1234730 Actinosynnema mirum DSM 43827 8325288 YP_003098917.1 CDS Amir_1115 NC_013093.1 1234746 1235456 D hypothetical protein 1234746..1235456 Actinosynnema mirum DSM 43827 8325289 YP_003098918.1 CDS Amir_1116 NC_013093.1 1235465 1236775 D hypothetical protein 1235465..1236775 Actinosynnema mirum DSM 43827 8325290 YP_003098919.1 CDS Amir_1118 NC_013093.1 1236951 1238105 D PFAM: integrase family protein; KEGG: xau:Xaut_0620 integrase family protein; integrase family protein 1236951..1238105 Actinosynnema mirum DSM 43827 8325292 YP_003098920.1 CDS Amir_1119 NC_013093.1 1238363 1239415 R PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: gox:GOX0577 transcriptional regulator; LacI family transcriptional regulator complement(1238363..1239415) Actinosynnema mirum DSM 43827 8325294 YP_003098921.1 CDS Amir_1120 NC_013093.1 1239473 1240663 D PFAM: major facilitator superfamily MFS_1; KEGG: rce:RC1_3733 major facilitator superfamily (MSF) transporter; major facilitator superfamily protein 1239473..1240663 Actinosynnema mirum DSM 43827 8325295 YP_003098922.1 CDS Amir_1121 NC_013093.1 1240629 1241213 R hypothetical protein complement(1240629..1241213) Actinosynnema mirum DSM 43827 8325296 YP_003098923.1 CDS Amir_1122 NC_013093.1 1241312 1243375 D PFAM: copper resistance D domain protein; KEGG: csa:Csal_0081 hypothetical protein; copper resistance D domain-containing protein 1241312..1243375 Actinosynnema mirum DSM 43827 8325297 YP_003098924.1 CDS Amir_1123 NC_013093.1 1243394 1244221 R PFAM: ABC transporter; KEGG: ank:AnaeK_4023 ABC transporter; ABC transporter complement(1243394..1244221) Actinosynnema mirum DSM 43827 8325298 YP_003098925.1 CDS Amir_1124 NC_013093.1 1244251 1245186 R KEGG: aeh:Mlg_2715 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; daunorubicin ABC transporter ATPase complement(1244251..1245186) Actinosynnema mirum DSM 43827 8325299 YP_003098926.1 CDS Amir_1125 NC_013093.1 1245171 1245803 R PFAM: regulatory protein TetR; KEGG: scl:sce5643 TetR family transcriptional regulator; TetR family transcriptional regulator complement(1245171..1245803) Actinosynnema mirum DSM 43827 8325300 YP_003098927.1 CDS Amir_1126 NC_013093.1 1246020 1246544 D TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: ajs:Ajs_4211 single-strand binding protein; single-strand binding protein 1246020..1246544 Actinosynnema mirum DSM 43827 8325301 YP_003098928.1 CDS Amir_1127 NC_013093.1 1246872 1248548 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1246872..1248548 Actinosynnema mirum DSM 43827 8325302 YP_003098929.1 CDS Amir_1128 NC_013093.1 1248616 1253604 D KEGG: apomucin; hypothetical protein 1248616..1253604 Actinosynnema mirum DSM 43827 8325303 YP_003098930.1 CDS Amir_1129 NC_013093.1 1253866 1258821 D PFAM: NAD-glutamate dehydrogenase; KEGG: pol:Bpro_3020 glutamate dehydrogenase (NAD); NAD-glutamate dehydrogenase 1253866..1258821 Actinosynnema mirum DSM 43827 8325304 YP_003098931.1 CDS Amir_1130 NC_013093.1 1258959 1260659 R PFAM: alpha amylase catalytic region; glycoside hydrolase starch-binding; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; alpha amylase all-beta; KEGG: sde:Sde_2938 ATPase; alpha amylase catalytic subunit complement(1258959..1260659) Actinosynnema mirum DSM 43827 8325305 YP_003098932.1 CDS Amir_1131 NC_013093.1 1260838 1261836 D KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 1260838..1261836 Actinosynnema mirum DSM 43827 8325306 YP_003098933.1 CDS Amir_1132 NC_013093.1 1261967 1262407 D PFAM: thioesterase superfamily protein; KEGG: xau:Xaut_1411 thioesterase superfamily protein; thioesterase superfamily protein 1261967..1262407 Actinosynnema mirum DSM 43827 8325307 YP_003098934.1 CDS Amir_1133 NC_013093.1 1262400 1263026 D hypothetical protein 1262400..1263026 Actinosynnema mirum DSM 43827 8325308 YP_003098935.1 CDS Amir_1134 NC_013093.1 1263090 1264685 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: alpha-glucosidase; K01187 alpha-glucosidase; alpha amylase catalytic subunit complement(1263090..1264685) Actinosynnema mirum DSM 43827 8325309 YP_003098936.1 CDS Amir_1135 NC_013093.1 1264763 1265146 R PFAM: globin; KEGG: bha:BH2854 hypothetical protein; globin complement(1264763..1265146) Actinosynnema mirum DSM 43827 8325310 YP_003098937.1 CDS Amir_1136 NC_013093.1 1265196 1266173 R PFAM: MscS Mechanosensitive ion channel; KEGG: tbd:Tbd_0499 mechanosensitive ion channel; mechanosensitive ion channel MscS complement(1265196..1266173) Actinosynnema mirum DSM 43827 8325311 YP_003098938.1 CDS Amir_1137 NC_013093.1 1266224 1268341 R PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: scl:sce8590 prolyl oligopeptidase; prolyl oligopeptidase complement(1266224..1268341) Actinosynnema mirum DSM 43827 8325312 YP_003098939.1 CDS Amir_1138 NC_013093.1 1268495 1269157 D PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: aba:Acid345_4201 HNH endonuclease; HNH endonuclease 1268495..1269157 Actinosynnema mirum DSM 43827 8325313 YP_003098940.1 CDS Amir_1139 NC_013093.1 1269177 1269764 R KEGG: RGD1561483, RGD1561483_predicted; similar to ankyrin repeat domain 26; hypothetical protein complement(1269177..1269764) Actinosynnema mirum DSM 43827 8325314 YP_003098941.1 CDS Amir_1140 NC_013093.1 1270087 1270323 D hypothetical protein 1270087..1270323 Actinosynnema mirum DSM 43827 8325315 YP_003098942.1 CDS Amir_1141 NC_013093.1 1270310 1270792 D hypothetical protein 1270310..1270792 Actinosynnema mirum DSM 43827 8325316 YP_003098943.1 CDS Amir_1142 NC_013093.1 1270865 1273423 R TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: scl:sce2331 membrane alanyl aminopeptidase; aminopeptidase N complement(1270865..1273423) Actinosynnema mirum DSM 43827 8325317 YP_003098944.1 CDS Amir_1143 NC_013093.1 1273645 1274259 D hypothetical protein 1273645..1274259 Actinosynnema mirum DSM 43827 8325318 YP_003098945.1 CDS Amir_1144 NC_013093.1 1274328 1275104 R KEGG: rpi:Rpic_1101 lipoprotein; lipoprotein complement(1274328..1275104) Actinosynnema mirum DSM 43827 8325319 YP_003098946.1 CDS Amir_1145 NC_013093.1 1275115 1275600 D TIGRFAM: ribose 5-phosphate isomerase; sugar- phosphate isomerase, RpiB/LacA/LacB family; PFAM: ribose/galactose isomerase; KEGG: mca:MCA0043 ribose 5-phosphate isomerase B; ribose 5-phosphate isomerase 1275115..1275600 Actinosynnema mirum DSM 43827 8325320 YP_003098947.1 CDS Amir_1146 NC_013093.1 1275600 1276274 D hypothetical protein 1275600..1276274 Actinosynnema mirum DSM 43827 8325321 YP_003098948.1 CDS Amir_1147 NC_013093.1 1276267 1277070 D PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; KEGG: hypothetical protein; DNA glycosylase/AP lyase 1276267..1277070 Actinosynnema mirum DSM 43827 8325322 YP_003098949.1 CDS Amir_1148 NC_013093.1 1277139 1277909 R KEGG: mno:Mnod_0189 periplasmic ligand- binding sensor protein; hypothetical protein complement(1277139..1277909) Actinosynnema mirum DSM 43827 8325323 YP_003098950.1 CDS Amir_1149 NC_013093.1 1278030 1279232 R KEGG: scl:sce0310 acetyltransferase; hypothetical protein complement(1278030..1279232) Actinosynnema mirum DSM 43827 8325324 YP_003098951.1 CDS Amir_1150 NC_013093.1 1279447 1280745 R hypothetical protein complement(1279447..1280745) Actinosynnema mirum DSM 43827 8325325 YP_003098952.1 CDS Amir_1151 NC_013093.1 1281568 1282476 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bsu:BSU36160 hypothetical protein; LysR family transcriptional regulator complement(1281568..1282476) Actinosynnema mirum DSM 43827 8325328 YP_003098953.1 CDS Amir_1152 NC_013093.1 1283560 1284912 D TIGRFAM: trigger factor; PFAM: trigger factor domain; trigger factor domain protein; peptidylprolyl isomerase FKBP-type; KEGG: bcr:BCAH187_A4609 trigger factor; trigger factor 1283560..1284912 Actinosynnema mirum DSM 43827 8325329 YP_003098954.1 CDS Amir_1153 NC_013093.1 1285072 1285701 D PFAM: peptidase S14 ClpP; KEGG: aba:Acid345_1560 ATP-dependent Clp protease proteolytic subunit ClpP; endopeptidase Clp 1285072..1285701 Actinosynnema mirum DSM 43827 8325330 YP_003098955.1 CDS clpX NC_013093.1 1285906 1287186 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1285906..1287186 Actinosynnema mirum DSM 43827 8325331 YP_003098956.1 CDS Amir_1155 NC_013093.1 1287190 1287780 D PFAM: protein of unknown function DUF1234; KEGG: nis:NIS_1664 hypothetical protein; hypothetical protein 1287190..1287780 Actinosynnema mirum DSM 43827 8325332 YP_003098957.1 CDS Amir_1156 NC_013093.1 1287802 1288710 R PFAM: esterase; KEGG: endo-1,4-beta-xylanase; esterase complement(1287802..1288710) Actinosynnema mirum DSM 43827 8325333 YP_003098958.1 CDS Amir_1157 NC_013093.1 1288906 1289730 R TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase subunit FdhD; KEGG: ade:Adeh_0826 formate dehydrogenase family accessory protein FdhD; formate dehydrogenase family accessory protein FdhD complement(1288906..1289730) Actinosynnema mirum DSM 43827 8325334 YP_003098959.1 CDS Amir_1158 NC_013093.1 1289798 1291144 D PFAM: major facilitator superfamily MFS_1; KEGG: nma:NMA1574 integral membrane transporter; major facilitator superfamily protein 1289798..1291144 Actinosynnema mirum DSM 43827 8325335 YP_003098960.1 CDS Amir_1159 NC_013093.1 1291141 1291293 D hypothetical protein 1291141..1291293 Actinosynnema mirum DSM 43827 8325336 YP_003098961.1 CDS Amir_1160 NC_013093.1 1291305 1292855 D PFAM: FAD dependent oxidoreductase; KEGG: acp:A2cp1_3444 amine oxidase; FAD dependent oxidoreductase 1291305..1292855 Actinosynnema mirum DSM 43827 8325337 YP_003098962.1 CDS Amir_1161 NC_013093.1 1292852 1293358 R hypothetical protein complement(1292852..1293358) Actinosynnema mirum DSM 43827 8325338 YP_003098963.1 CDS Amir_1162 NC_013093.1 1293355 1295646 R KEGG: mxa:MXAN_4341 oxidoreductase alpha (molybdopterin) subunit; TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; oxidoreductase alpha (molybdopterin) subunit complement(1293355..1295646) Actinosynnema mirum DSM 43827 8325339 YP_003098964.1 CDS Amir_1163 NC_013093.1 1295657 1296070 R hypothetical protein complement(1295657..1296070) Actinosynnema mirum DSM 43827 8325340 YP_003098965.1 CDS Amir_1164 NC_013093.1 1296419 1297438 R KEGG: ade:Adeh_3310 zinc finger/thioredoxin; hypothetical protein complement(1296419..1297438) Actinosynnema mirum DSM 43827 8325341 YP_003098966.1 CDS valS NC_013093.1 1297729 1300362 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1297729..1300362 Actinosynnema mirum DSM 43827 8325342 YP_003098967.1 CDS Amir_1166 NC_013093.1 1300362 1301720 D TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase; FolC bifunctional protein 1300362..1301720 Actinosynnema mirum DSM 43827 8325343 YP_003098968.1 CDS Amir_1167 NC_013093.1 1301717 1302172 D hypothetical protein 1301717..1302172 Actinosynnema mirum DSM 43827 8325344 YP_003098969.1 CDS Amir_1168 NC_013093.1 1302376 1302510 D hypothetical protein 1302376..1302510 Actinosynnema mirum DSM 43827 8325345 YP_003098970.1 CDS Amir_1170 NC_013093.1 1303945 1309512 D KEGG: aba:Acid345_2329 alpha-1,6-glucosidases, pullulanase-type; TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: alpha amylase catalytic region; pullanase- associated protein; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; alpha-1,6-glucosidase, pullulanase-type 1303945..1309512 Actinosynnema mirum DSM 43827 8325347 YP_003098971.1 CDS Amir_1171 NC_013093.1 1309544 1310188 R hypothetical protein complement(1309544..1310188) Actinosynnema mirum DSM 43827 8325348 YP_003098972.1 CDS Amir_1172 NC_013093.1 1310265 1310675 D KEGG: bsu:BSU22730 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase; Nucleoside-diphosphate kinase 1310265..1310675 Actinosynnema mirum DSM 43827 8325349 YP_003098973.1 CDS Amir_1173 NC_013093.1 1310810 1311730 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mgm:Mmc1_3306 ABC transporter; ABC transporter 1310810..1311730 Actinosynnema mirum DSM 43827 8325350 YP_003098974.1 CDS Amir_1174 NC_013093.1 1311730 1312566 D PFAM: ABC transporter; KEGG: hha:Hhal_0239 ABC transporter, NodJ family; ABC transporter 1311730..1312566 Actinosynnema mirum DSM 43827 8325351 YP_003098975.1 CDS Amir_1175 NC_013093.1 1312563 1313369 D PFAM: ABC transporter; KEGG: afr:AFE_3235 ABC transporter, permease protein, NodJ family; ABC transporter 1312563..1313369 Actinosynnema mirum DSM 43827 8325352 YP_003098976.1 CDS Amir_1176 NC_013093.1 1313403 1315370 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pca:Pcar_2585 Fe-S oxidoreductase; Radical SAM domain-containing protein 1313403..1315370 Actinosynnema mirum DSM 43827 8325353 YP_003098977.1 CDS Amir_1177 NC_013093.1 1315762 1316313 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: aba:Acid345_1825 sigma-24, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 1315762..1316313 Actinosynnema mirum DSM 43827 8325354 YP_003098978.1 CDS Amir_1178 NC_013093.1 1316811 1320125 D PFAM: regulatory protein LuxR; hypothetical protein; hypothetical protein; SMART: regulatory protein LuxR; hypothetical protein; KEGG: ade:Adeh_3797 hypothetical protein; LuxR family transcriptional regulator 1316811..1320125 Actinosynnema mirum DSM 43827 8325355 YP_003098979.1 CDS Amir_1181 NC_013093.1 1321093 1321632 R PFAM: Ferric reductase domain protein transmembrane component domain; KEGG: prw:PsycPRwf_0697 ferric reductase-like protein; ferric reductase transmembrane domain-containing protein complement(1321093..1321632) Actinosynnema mirum DSM 43827 8325358 YP_003098980.1 CDS Amir_1182 NC_013093.1 1321629 1322525 R PFAM: ApbE family lipoprotein; KEGG: mca:MCA2411 thiamine biosynthesis lipoprotein ApbE; ApbE family lipoprotein complement(1321629..1322525) Actinosynnema mirum DSM 43827 8325359 YP_003098981.1 CDS Amir_1183 NC_013093.1 1322534 1322944 R KEGG: HYR10; hyphally-regulated cell wall protein; hypothetical protein complement(1322534..1322944) Actinosynnema mirum DSM 43827 8325360 YP_003098982.1 CDS Amir_1184 NC_013093.1 1323018 1324721 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: acp:A2cp1_0256 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin complement(1323018..1324721) Actinosynnema mirum DSM 43827 8325361 YP_003098983.1 CDS Amir_1185 NC_013093.1 1324981 1325721 D KEGG: glo:Glov_0470 radical SAM domain protein; hypothetical protein 1324981..1325721 Actinosynnema mirum DSM 43827 8325362 YP_003098984.1 CDS Amir_1186 NC_013093.1 1325914 1328838 D KEGG: sde:Sde_3188 RNAse G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: translation initiation factor IF-2 domain protein; SMART: RNA binding S1 domain protein; ribonuclease, Rne/Rng family 1325914..1328838 Actinosynnema mirum DSM 43827 8325363 YP_003098985.1 CDS Amir_1187 NC_013093.1 1329415 1329726 D TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: tbd:Tbd_0864 50S ribosomal protein L21P; 50S ribosomal protein L21 1329415..1329726 Actinosynnema mirum DSM 43827 8325364 YP_003098986.1 CDS rpmA NC_013093.1 1329741 1330004 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1329741..1330004 Actinosynnema mirum DSM 43827 8325365 YP_003098987.1 CDS obgE NC_013093.1 1330117 1331583 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1330117..1331583 Actinosynnema mirum DSM 43827 8325366 YP_003098988.1 CDS Amir_1190 NC_013093.1 1331586 1332716 D KEGG: mxa:MXAN_1357 glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; glutamate 5-kinase 1331586..1332716 Actinosynnema mirum DSM 43827 8325367 YP_003098989.1 CDS Amir_1191 NC_013093.1 1332889 1334169 R PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: bav:BAV1823 alpha-ketoglutarate permease; major facilitator superfamily protein complement(1332889..1334169) Actinosynnema mirum DSM 43827 8325368 YP_003098990.1 CDS Amir_1192 NC_013093.1 1334248 1334793 R PFAM: GCN5-related N-acetyltransferase; KEGG: bpl:BURPS1106A_2024 acetyltransferase; GCN5-like N-acetyltransferase complement(1334248..1334793) Actinosynnema mirum DSM 43827 8325369 YP_003098991.1 CDS Amir_1193 NC_013093.1 1335135 1337210 R KEGG: maq:Maqu_0559 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; RecQ family ATP-dependent DNA helicase complement(1335135..1337210) Actinosynnema mirum DSM 43827 8325370 YP_003098992.1 CDS proA NC_013093.1 1337301 1338563 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1337301..1338563 Actinosynnema mirum DSM 43827 8325371 YP_003098993.1 CDS Amir_1195 NC_013093.1 1338679 1339863 D PFAM: cytochrome P450; KEGG: scl:sce8913 cytochrome P450 CYP109C2; cytochrome P450 1338679..1339863 Actinosynnema mirum DSM 43827 8325372 YP_003098994.1 CDS Amir_1196 NC_013093.1 1339866 1340087 D KEGG: bha:BH1605 ferredoxin; hypothetical protein 1339866..1340087 Actinosynnema mirum DSM 43827 8325373 YP_003098995.1 CDS Amir_1197 NC_013093.1 1340162 1340755 D KEGG: bsu:BSU25640 nicotinic acid mononucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; nicotinate (nicotinamide) nucleotide adenylyltransferase 1340162..1340755 Actinosynnema mirum DSM 43827 8325374 YP_003098996.1 CDS Amir_1198 NC_013093.1 1340880 1341326 D TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: ank:AnaeK_0226 iojap-like protein; iojap-like protein 1340880..1341326 Actinosynnema mirum DSM 43827 8325375 YP_003098997.1 CDS Amir_1199 NC_013093.1 1341323 1341937 D PFAM: phosphoglycerate mutase; KEGG: reh:H16_A0493 phosphoglycerate mutase 2 protein; phosphoglycerate mutase 1341323..1341937 Actinosynnema mirum DSM 43827 8325376 YP_003098998.1 CDS Amir_1200 NC_013093.1 1341934 1342665 D hypothetical protein 1341934..1342665 Actinosynnema mirum DSM 43827 8325377 YP_003098999.1 CDS Amir_1201 NC_013093.1 1342677 1343519 D TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: bsu:BSU35480 hypothetical protein; degV family protein 1342677..1343519 Actinosynnema mirum DSM 43827 8325378 YP_003099000.1 CDS Amir_1202 NC_013093.1 1343627 1344355 D TIGRFAM: competence protein ComEA helix-hairpin- helix repeat protein; PFAM: helix-hairpin-helix motif; KEGG: bsu:BSU25590 unspecific high-affinity DNA- binding protein; competence protein ComEA helix-hairpin-helix repeat-containing protein 1343627..1344355 Actinosynnema mirum DSM 43827 8325379 YP_003099001.1 CDS Amir_1203 NC_013093.1 1344723 1347035 D TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase domain protein; KEGG: ank:AnaeK_2593 DNA internalization-related competence protein ComEC/Rec2; DNA internalization-related competence protein ComEC/Rec2 1344723..1347035 Actinosynnema mirum DSM 43827 8325380 YP_003099002.1 CDS Amir_1204 NC_013093.1 1347105 1347572 D hypothetical protein 1347105..1347572 Actinosynnema mirum DSM 43827 8325381 YP_003099003.1 CDS Amir_1205 NC_013093.1 1348001 1349266 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(1348001..1349266) Actinosynnema mirum DSM 43827 8325382 YP_003099004.1 CDS Amir_1206 NC_013093.1 1349509 1350477 D TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: gbm:Gbem_0755 DNA polymerase III, delta subunit; hypothetical protein 1349509..1350477 Actinosynnema mirum DSM 43827 8325383 YP_003099005.1 CDS Amir_1207 NC_013093.1 1351197 1351457 R TIGRFAM: ribosomal protein S20; PFAM: ribosomal protein S20; KEGG: bha:BH1339 30S ribosomal protein S20; 30S ribosomal protein S20 complement(1351197..1351457) Actinosynnema mirum DSM 43827 8325384 YP_003099006.1 CDS Amir_1208 NC_013093.1 1351726 1352529 D PFAM: protein of unknown function DUF81; KEGG: ppg:PputGB1_3567 hypothetical protein; hypothetical protein 1351726..1352529 Actinosynnema mirum DSM 43827 8325385 YP_003099007.1 CDS Amir_1209 NC_013093.1 1352498 1353268 R PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_0263 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase complement(1352498..1353268) Actinosynnema mirum DSM 43827 8325386 YP_003099008.1 CDS Amir_1210 NC_013093.1 1353558 1353821 R KEGG: sal:Sala_0218 hypothetical protein; hypothetical protein complement(1353558..1353821) Actinosynnema mirum DSM 43827 8325387 YP_003099009.1 CDS Amir_1211 NC_013093.1 1353823 1354740 R PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: sml:Smlt1263 transmembrane protein; hypothetical protein complement(1353823..1354740) Actinosynnema mirum DSM 43827 8325388 YP_003099010.1 CDS Amir_1212 NC_013093.1 1354882 1355235 D hypothetical protein 1354882..1355235 Actinosynnema mirum DSM 43827 8325389 YP_003099011.1 CDS Amir_1213 NC_013093.1 1355645 1357306 D PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: aba:Acid345_3320 protein of unknown function DUF404; hypothetical protein 1355645..1357306 Actinosynnema mirum DSM 43827 8325390 YP_003099012.1 CDS Amir_1214 NC_013093.1 1357306 1358250 D PFAM: protein of unknown function DUF403; KEGG: aba:Acid345_3319 protein of unknown function DUF403; hypothetical protein 1357306..1358250 Actinosynnema mirum DSM 43827 8325391 YP_003099013.1 CDS Amir_1215 NC_013093.1 1358251 1359093 D PFAM: transglutaminase domain protein; transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: ccs:CCNA_01672 transglutaminase-like enzyme, cysteine; transglutaminase domain-containing protein 1358251..1359093 Actinosynnema mirum DSM 43827 8325392 YP_003099014.1 CDS Amir_1216 NC_013093.1 1359587 1361428 R TIGRFAM: GTP-binding protein LepA; small GTP- binding protein; PFAM: GTP-binding protein LepA domain protein; elongation factor G domain protein; elongation factor Tu domain 2 protein; protein synthesis factor GTP-binding; KEGG: bcy:Bcer98_3046 GTP-binding protein LepA; GTP-binding protein LepA complement(1359587..1361428) Actinosynnema mirum DSM 43827 8325393 YP_003099015.1 CDS Amir_1217 NC_013093.1 1361535 1361978 D hypothetical protein 1361535..1361978 Actinosynnema mirum DSM 43827 8325394 YP_003099016.1 CDS Amir_1218 NC_013093.1 1362127 1362345 R hypothetical protein complement(1362127..1362345) Actinosynnema mirum DSM 43827 8325395 YP_003099017.1 CDS Amir_1219 NC_013093.1 1362457 1362888 R KEGG: pen:PSEEN1948 hypothetical protein; hypothetical protein complement(1362457..1362888) Actinosynnema mirum DSM 43827 8325396 YP_003099018.1 CDS Amir_1220 NC_013093.1 1363011 1364543 D PFAM: carbohydrate-binding CenC domain protein; glycoside hydrolase family 18; SMART: chitinase II; KEGG: cja:CJA_2993 endo-chitinase, , chi18C; carbohydrate-binding CenC domain-containing protein 1363011..1364543 Actinosynnema mirum DSM 43827 8325397 YP_003099019.1 CDS Amir_1221 NC_013093.1 1364625 1365668 D PFAM: 2-nitropropane dioxygenase NPD; KEGG: bpt:Bpet3829 2-nitropropane dioxygenase; 2-nitropropane dioxygenase NPD 1364625..1365668 Actinosynnema mirum DSM 43827 8325398 YP_003099020.1 CDS Amir_1222 NC_013093.1 1365699 1367339 D PFAM: protein of unknown function DUF885; KEGG: sal:Sala_0679 hypothetical protein; hypothetical protein 1365699..1367339 Actinosynnema mirum DSM 43827 8325399 YP_003099021.1 CDS Amir_1223 NC_013093.1 1367331 1368803 R PFAM: amino acid permease-associated region; KEGG: bsu:BSU07340 hypothetical protein; amino acid permease-associated protein complement(1367331..1368803) Actinosynnema mirum DSM 43827 8325400 YP_003099022.1 CDS Amir_1224 NC_013093.1 1369041 1369808 D PFAM: Enoyl-CoA hydratase/isomerase; KEGG: reu:Reut_A1464 enoyl-CoA hydratase; Enoyl-CoA hydratase/isomerase 1369041..1369808 Actinosynnema mirum DSM 43827 8325401 YP_003099023.1 CDS Amir_1225 NC_013093.1 1369842 1370810 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: xcv:XCV2170 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein complement(1369842..1370810) Actinosynnema mirum DSM 43827 8325402 YP_003099024.1 CDS Amir_1226 NC_013093.1 1370877 1371125 D hypothetical protein 1370877..1371125 Actinosynnema mirum DSM 43827 8325403 YP_003099025.1 CDS Amir_1227 NC_013093.1 1371135 1371575 D PFAM: guanine-specific ribonuclease N1 and T1; KEGG: tmz:Tmz1t_1168 guanine-specific ribonuclease N1 and T1; guanine-specific ribonuclease N1 and T1 1371135..1371575 Actinosynnema mirum DSM 43827 8325404 YP_003099026.1 CDS Amir_1228 NC_013093.1 1371572 1371910 D PFAM: Barstar (barnase inhibitor); KEGG: tmz:Tmz1t_1167 barstar (barnase inhibitor); Barstar (barnase inhibitor) 1371572..1371910 Actinosynnema mirum DSM 43827 8325405 YP_003099027.1 CDS Amir_1229 NC_013093.1 1372023 1372244 D PFAM: protein of unknown function UPF0150; KEGG: dar:Daro_3012 hypothetical protein; hypothetical protein 1372023..1372244 Actinosynnema mirum DSM 43827 8325406 YP_003099028.1 CDS Amir_1230 NC_013093.1 1372241 1372462 D PFAM: YcfA family protein; KEGG: abu:Abu_0898 hypothetical protein; YcfA family protein 1372241..1372462 Actinosynnema mirum DSM 43827 8325407 YP_003099029.1 CDS Amir_1231 NC_013093.1 1372542 1373258 R PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: cvi:CV_1567 precorrin-8X methylmutase; cobalamin (vitamin B12) biosynthesis CbiX protein complement(1372542..1373258) Actinosynnema mirum DSM 43827 8325408 YP_003099030.1 CDS Amir_1232 NC_013093.1 1373267 1374226 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: aba:Acid345_0827 ABC aliphatic sulfonate transporter, inner membrane subunit; ABC transporter inner membrane protein complement(1373267..1374226) Actinosynnema mirum DSM 43827 8325409 YP_003099031.1 CDS Amir_1233 NC_013093.1 1374207 1374995 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0826 ABC transporter, ATPase subunit; ABC transporter complement(1374207..1374995) Actinosynnema mirum DSM 43827 8325410 YP_003099032.1 CDS Amir_1234 NC_013093.1 1375026 1376084 R TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; KEGG: afw:Anae109_0427 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein complement(1375026..1376084) Actinosynnema mirum DSM 43827 8325411 YP_003099033.1 CDS Amir_1235 NC_013093.1 1376144 1377478 R KEGG: afw:Anae109_1643 sulfate adenylyltransferase, large subunit; TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; sulfate adenylyltransferase, large subunit complement(1376144..1377478) Actinosynnema mirum DSM 43827 8325412 YP_003099034.1 CDS Amir_1236 NC_013093.1 1377479 1378378 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(1377479..1378378) Actinosynnema mirum DSM 43827 8325413 YP_003099035.1 CDS Amir_1237 NC_013093.1 1378375 1379070 R TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate; adenylylsulfate reductase, thioredoxin dependent complement(1378375..1379070) Actinosynnema mirum DSM 43827 8325414 YP_003099036.1 CDS Amir_1238 NC_013093.1 1379067 1379225 R hypothetical protein complement(1379067..1379225) Actinosynnema mirum DSM 43827 8325415 YP_003099037.1 CDS Amir_1239 NC_013093.1 1379222 1380934 R PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: aba:Acid345_2373 nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like; sulfite reductase complement(1379222..1380934) Actinosynnema mirum DSM 43827 8325416 YP_003099038.1 CDS Amir_1240 NC_013093.1 1381347 1382561 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1381347..1382561 Actinosynnema mirum DSM 43827 8325417 YP_003099039.1 CDS hrcA NC_013093.1 1383074 1384096 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1383074..1384096 Actinosynnema mirum DSM 43827 8325418 YP_003099040.1 CDS Amir_1242 NC_013093.1 1384183 1385337 D PFAM: chaperone DnaJ domain protein; DnaJ central domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: afr:AFE_2664 chaperone protein DnaJ; chaperone DnaJ domain-containing protein 1384183..1385337 Actinosynnema mirum DSM 43827 8325419 YP_003099041.1 CDS Amir_1243 NC_013093.1 1385334 1386068 D PFAM: protein of unknown function DUF558; KEGG: xca:xccb100_1268 hypothetical protein; hypothetical protein 1385334..1386068 Actinosynnema mirum DSM 43827 8325420 YP_003099042.1 CDS Amir_1244 NC_013093.1 1386261 1387475 R PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce5221 hypothetical protein; G-D-S-L family lipolytic protein complement(1386261..1387475) Actinosynnema mirum DSM 43827 8325421 YP_003099043.1 CDS Amir_1245 NC_013093.1 1387590 1388834 R PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce5221 hypothetical protein; G-D-S-L family lipolytic protein complement(1387590..1388834) Actinosynnema mirum DSM 43827 8325422 YP_003099044.1 CDS Amir_1246 NC_013093.1 1389005 1389670 D KEGG: mxa:MXAN_0913 hypothetical protein; hypothetical protein 1389005..1389670 Actinosynnema mirum DSM 43827 8325423 YP_003099045.1 CDS Amir_1247 NC_013093.1 1389680 1390021 D PFAM: histidine triad (HIT) protein; KEGG: afw:Anae109_0197 histidine triad (HIT) protein; histidine triad (HIT) protein 1389680..1390021 Actinosynnema mirum DSM 43827 8325424 YP_003099046.1 CDS Amir_1248 NC_013093.1 1390034 1390825 R PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_L_2832 hypothetical protein; GCN5-like N-acetyltransferase complement(1390034..1390825) Actinosynnema mirum DSM 43827 8325425 YP_003099047.1 CDS Amir_1249 NC_013093.1 1390958 1392922 D PFAM: PhoH family protein; SMART: Hedgehog/intein hint domain protein; KEGG: mxa:MXAN_4738 PhoH family protein; PhoH family protein 1390958..1392922 Actinosynnema mirum DSM 43827 8325426 YP_003099048.1 CDS Amir_1250 NC_013093.1 1392928 1393491 D PFAM: protein of unknown function UPF0054; KEGG: bsu:BSU25320 metalloprotease; metalloprotease 1392928..1393491 Actinosynnema mirum DSM 43827 8325427 YP_003099049.1 CDS Amir_1251 NC_013093.1 1393502 1394809 D PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; SMART: CBS domain containing protein; KEGG: scl:sce4286 hypothetical protein; CBS domain-containing protein 1393502..1394809 Actinosynnema mirum DSM 43827 8325428 YP_003099050.1 CDS Amir_1252 NC_013093.1 1394802 1395134 D KEGG: acp:A2cp1_0654 cytidine deaminase; cytidine deaminase 1394802..1395134 Actinosynnema mirum DSM 43827 8325429 YP_003099051.1 CDS Amir_1253 NC_013093.1 1395135 1395479 D KEGG: net:Neut_1332 ferredoxin 2fe-2s protein; hypothetical protein 1395135..1395479 Actinosynnema mirum DSM 43827 8325430 YP_003099052.1 CDS era NC_013093.1 1396007 1396903 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1396007..1396903 Actinosynnema mirum DSM 43827 8325431 YP_003099053.1 CDS recO NC_013093.1 1396904 1397656 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1396904..1397656 Actinosynnema mirum DSM 43827 8325432 YP_003099054.1 CDS Amir_1256 NC_013093.1 1397691 1398557 D KEGG: acr:Acry_2555 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase 1397691..1398557 Actinosynnema mirum DSM 43827 8325433 YP_003099055.1 CDS Amir_1257 NC_013093.1 1398554 1398982 D hypothetical protein 1398554..1398982 Actinosynnema mirum DSM 43827 8325434 YP_003099056.1 CDS Amir_1258 NC_013093.1 1398985 1399269 D hypothetical protein 1398985..1399269 Actinosynnema mirum DSM 43827 8325435 YP_003099057.1 CDS Amir_1259 NC_013093.1 1399357 1400361 D PFAM: permease; KEGG: bcy:Bcer98_1540 permease; permease 1399357..1400361 Actinosynnema mirum DSM 43827 8325436 YP_003099058.1 CDS Amir_1260 NC_013093.1 1400358 1401101 D KEGG: bcy:Bcer98_1541 hypothetical protein; hypothetical protein 1400358..1401101 Actinosynnema mirum DSM 43827 8325437 YP_003099059.1 CDS Amir_1261 NC_013093.1 1401185 1401610 R PFAM: ferric-uptake regulator; KEGG: gur:Gura_3002 ferric uptake regulator family protein; Fur family ferric uptake regulator complement(1401185..1401610) Actinosynnema mirum DSM 43827 8325438 YP_003099060.1 CDS Amir_1262 NC_013093.1 1401607 1402008 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: pla:Plav_2471 regulatory protein ArsR; ArsR family transcriptional regulator complement(1401607..1402008) Actinosynnema mirum DSM 43827 8325439 YP_003099061.1 CDS Amir_1263 NC_013093.1 1402192 1402575 D PFAM: Antibiotic biosynthesis monooxygenase; Antibiotic biosynthesis monooxygenase 1402192..1402575 Actinosynnema mirum DSM 43827 8325440 YP_003099062.1 CDS Amir_1264 NC_013093.1 1403437 1403655 D hypothetical protein 1403437..1403655 Actinosynnema mirum DSM 43827 8325441 YP_003099063.1 CDS Amir_1265 NC_013093.1 1403717 1404079 D hypothetical protein 1403717..1404079 Actinosynnema mirum DSM 43827 8325442 YP_003099064.1 CDS Amir_1266 NC_013093.1 1404226 1405611 D Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1404226..1405611 Actinosynnema mirum DSM 43827 8325443 YP_003099065.1 CDS Amir_1267 NC_013093.1 1405985 1406311 D hypothetical protein 1405985..1406311 Actinosynnema mirum DSM 43827 8325444 YP_003099066.1 CDS Amir_1268 NC_013093.1 1406406 1407041 D PFAM: carbonic anhydrase; KEGG: bac:BamMC406_5701 carbonate dehydratase; carbonate dehydratase 1406406..1407041 Actinosynnema mirum DSM 43827 8325445 YP_003099067.1 CDS Amir_1269 NC_013093.1 1407128 1408585 D PFAM: sulphate transporter; xanthine/uracil/vitamin C permease; KEGG: psa:PST_4161 probable sulfate transporter; sulfate transporter 1407128..1408585 Actinosynnema mirum DSM 43827 8325446 YP_003099068.1 CDS Amir_1270 NC_013093.1 1408642 1409697 R PFAM: proteinase inhibitor I4 serpin; SMART: proteinase inhibitor I4 serpin; KEGG: scl:sce5377 hypothetical protein; proteinase inhibitor I4 serpin complement(1408642..1409697) Actinosynnema mirum DSM 43827 8325447 YP_003099069.1 CDS Amir_1271 NC_013093.1 1409766 1411016 R KEGG: aba:Acid345_0225 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; deoxyguanosinetriphosphate triphosphohydrolase complement(1409766..1411016) Actinosynnema mirum DSM 43827 8325448 YP_003099070.1 CDS Amir_1272 NC_013093.1 1411087 1411725 R PFAM: protein of unknown function DUF218; KEGG: aba:Acid345_2611 protein of unknown function DUF218; hypothetical protein complement(1411087..1411725) Actinosynnema mirum DSM 43827 8325449 YP_003099071.1 CDS Amir_1273 NC_013093.1 1411882 1412607 D PFAM: peptidase S51 dipeptidase E; KEGG: bsu:BSU08780 hypothetical protein; peptidase S51 dipeptidase E 1411882..1412607 Actinosynnema mirum DSM 43827 8325450 YP_003099072.1 CDS Amir_1274 NC_013093.1 1412633 1413622 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mno:Mnod_3704 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit complement(1412633..1413622) Actinosynnema mirum DSM 43827 8325451 YP_003099073.1 CDS Amir_1275 NC_013093.1 1413651 1415540 D KEGG: DNA primase; K02316 DNA primase; TIGRFAM: DNA primase; PFAM: DNA primase catalytic core domain; zinc finger CHC2-family protein; TOPRIM domain protein; DNA primase DnaG DnaB-binding; SMART: zinc finger CHC2-family protein; DNA primase DnaG DnaB-binding; Toprim sub domain protein; DNA primase 1413651..1415540 Actinosynnema mirum DSM 43827 8325452 YP_003099074.1 CDS Amir_1276 NC_013093.1 1415610 1416149 D KEGG: reu:Reut_A2115 DNA helicase/exodeoxyribonuclease V, subunit B; hypothetical protein 1415610..1416149 Actinosynnema mirum DSM 43827 8325453 YP_003099075.1 CDS Amir_1277 NC_013093.1 1416723 1416953 R hypothetical protein complement(1416723..1416953) Actinosynnema mirum DSM 43827 8325454 YP_003099076.1 CDS Amir_1278 NC_013093.1 1417386 1417943 D PFAM: NUDIX hydrolase; KEGG: kpn:KPN_04028 hypothetical protein; NUDIX hydrolase 1417386..1417943 Actinosynnema mirum DSM 43827 8325455 YP_003099077.1 CDS Amir_1279 NC_013093.1 1417952 1418599 R PFAM: protein of unknown function DUF218; KEGG: ppr:PBPRB0680 hypothetical protein; hypothetical protein complement(1417952..1418599) Actinosynnema mirum DSM 43827 8325456 YP_003099078.1 CDS Amir_1280 NC_013093.1 1418628 1419329 R PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: rme:Rmet_2856 transcriptional regulator, histidine utilization repressor, GntR family; GntR family transcriptional regulator complement(1418628..1419329) Actinosynnema mirum DSM 43827 8325457 YP_003099079.1 CDS Amir_1281 NC_013093.1 1419402 1420661 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: afw:Anae109_2699 response regulator receiver; XRE family transcriptional regulator complement(1419402..1420661) Actinosynnema mirum DSM 43827 8325458 YP_003099080.1 CDS Amir_1282 NC_013093.1 1420673 1421083 R PFAM: NUDIX hydrolase; KEGG: rpi:Rpic_3754 NUDIX hydrolase; NUDIX hydrolase complement(1420673..1421083) Actinosynnema mirum DSM 43827 8325459 YP_003099081.1 CDS Amir_1283 NC_013093.1 1421239 1421991 D PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: hypothetical protein; taurine catabolism dioxygenase TauD/TfdA 1421239..1421991 Actinosynnema mirum DSM 43827 8325460 YP_003099082.1 CDS Amir_1284 NC_013093.1 1422483 1423250 D PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dar:Daro_2866 GntR family transcriptional regulator; GntR family transcriptional regulator 1422483..1423250 Actinosynnema mirum DSM 43827 8325461 YP_003099083.1 CDS Amir_1285 NC_013093.1 1423390 1423722 D hypothetical protein 1423390..1423722 Actinosynnema mirum DSM 43827 8325462 YP_003099084.1 CDS Amir_1286 NC_013093.1 1423975 1424244 D hypothetical protein 1423975..1424244 Actinosynnema mirum DSM 43827 8325463 YP_003099085.1 CDS Amir_1287 NC_013093.1 1424246 1424437 D hypothetical protein 1424246..1424437 Actinosynnema mirum DSM 43827 8325464 YP_003099086.1 CDS Amir_1288 NC_013093.1 1424529 1425899 D PFAM: cell divisionFtsK/SpoIIIE; KEGG: bac:BamMC406_0006 cell divisionFtsK/SpoIIIE; cell division protein FtsK/SpoIIIE 1424529..1425899 Actinosynnema mirum DSM 43827 8325465 YP_003099087.1 CDS Amir_1289 NC_013093.1 1425970 1426185 D hypothetical protein 1425970..1426185 Actinosynnema mirum DSM 43827 8325466 YP_003099088.1 CDS Amir_1290 NC_013093.1 1426182 1427096 D KEGG: hypothetical protein; K11233 osomolarity two- component system, response regulator SSK1; hypothetical protein 1426182..1427096 Actinosynnema mirum DSM 43827 8325467 YP_003099089.1 CDS Amir_1291 NC_013093.1 1427123 1427620 D hypothetical protein 1427123..1427620 Actinosynnema mirum DSM 43827 8325468 YP_003099090.1 CDS Amir_1292 NC_013093.1 1427716 1429059 D hypothetical protein 1427716..1429059 Actinosynnema mirum DSM 43827 8325469 YP_003099091.1 CDS Amir_1293 NC_013093.1 1429056 1429235 D PFAM: regulatory protein MerR; KEGG: nwi:Nwi_0824 hypothetical protein; MerR family transcriptional regulator 1429056..1429235 Actinosynnema mirum DSM 43827 8325470 YP_003099092.1 CDS Amir_1294 NC_013093.1 1429235 1430416 D PFAM: integrase family protein; KEGG: bat:BAS0415 prophage LambdaBa04, site- specific recombinase phage integrase family protein protein; integrase family protein 1429235..1430416 Actinosynnema mirum DSM 43827 8325471 YP_003099093.1 CDS Amir_1295 NC_013093.1 1430635 1431480 R KEGG: scl:sce5771 hypothetical protein; hypothetical protein complement(1430635..1431480) Actinosynnema mirum DSM 43827 8325473 YP_003099094.1 CDS Amir_1296 NC_013093.1 1431847 1432089 D hypothetical protein 1431847..1432089 Actinosynnema mirum DSM 43827 8325475 YP_003099095.1 CDS Amir_1297 NC_013093.1 1432109 1432858 R catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase complement(1432109..1432858) Actinosynnema mirum DSM 43827 8325476 YP_003099096.1 CDS Amir_1298 NC_013093.1 1432995 1433408 D hypothetical protein 1432995..1433408 Actinosynnema mirum DSM 43827 8325477 YP_003099097.1 CDS Amir_1299 NC_013093.1 1433548 1434570 R TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bce:BC5265 membrane-bound transcriptional regulator LytR; cell envelope-related transcriptional attenuator complement(1433548..1434570) Actinosynnema mirum DSM 43827 8325478 YP_003099098.1 CDS Amir_1300 NC_013093.1 1434624 1435049 D KEGG: afw:Anae109_0856 hypothetical protein; hypothetical protein 1434624..1435049 Actinosynnema mirum DSM 43827 8325479 YP_003099099.1 CDS Amir_1301 NC_013093.1 1435129 1437042 D PFAM: glycosyl transferase family 2; polysaccharide deacetylase; KEGG: mno:Mnod_3023 polysaccharide deacetylase; family 2 glycosyl transferase 1435129..1437042 Actinosynnema mirum DSM 43827 8325480 YP_003099100.1 CDS Amir_1302 NC_013093.1 1437100 1438302 R PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 complement(1437100..1438302) Actinosynnema mirum DSM 43827 8325481 YP_003099101.1 CDS Amir_1303 NC_013093.1 1438928 1440088 D PFAM: nitric oxide synthase NOS; KEGG: scl:sce1582 nitric-oxide synthase, oxygenase subunit; nitric-oxide synthase 1438928..1440088 Actinosynnema mirum DSM 43827 8325482 YP_003099102.1 CDS Amir_1304 NC_013093.1 1440187 1441296 D PFAM: alanine dehydrogenase/PNT domain protein; KEGG: eba:ebA4497 pyridine nucleotide transhydrogenase alpha subunit; alanine dehydrogenase/PNT domain-containing protein 1440187..1441296 Actinosynnema mirum DSM 43827 8325483 YP_003099103.1 CDS Amir_1305 NC_013093.1 1441325 1441693 R hypothetical protein complement(1441325..1441693) Actinosynnema mirum DSM 43827 8325484 YP_003099104.1 CDS Amir_1306 NC_013093.1 1441947 1444025 R KEGG: dvm:DvMF_0211 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; EAL domain protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase complement(1441947..1444025) Actinosynnema mirum DSM 43827 8325485 YP_003099105.1 CDS Amir_1307 NC_013093.1 1444032 1444856 R PFAM: protein of unknown function DUF574; methyltransferase type 12; KEGG: scl:sce6070 hypothetical protein; hypothetical protein complement(1444032..1444856) Actinosynnema mirum DSM 43827 8325486 YP_003099106.1 CDS Amir_1308 NC_013093.1 1445048 1445617 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bmj:BMULJ_04432 MarR family transcriptional regulator; MarR family transcriptional regulator 1445048..1445617 Actinosynnema mirum DSM 43827 8325487 YP_003099107.1 CDS Amir_1309 NC_013093.1 1445668 1446042 D PFAM: camphor resistance CrcB protein; KEGG: eli:ELI_01350 hypothetical protein; camphor resistance CrcB protein 1445668..1446042 Actinosynnema mirum DSM 43827 8325488 YP_003099108.1 CDS Amir_1310 NC_013093.1 1446039 1446383 D TIGRFAM: CrcB protein; PFAM: camphor resistance CrcB protein; KEGG: smd:Smed_1020 CrcB protein; CrcB protein 1446039..1446383 Actinosynnema mirum DSM 43827 8325489 YP_003099109.1 CDS Amir_1311 NC_013093.1 1446409 1448655 R KEGG: bcr:BCAH187_A2861 UvrD/Rep helicase family protein; superfamily I DNA and RNA helicase-like protein complement(1446409..1448655) Actinosynnema mirum DSM 43827 8325490 YP_003099110.1 CDS Amir_1312 NC_013093.1 1449434 1450459 D PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: dvm:DvMF_2927 2-hydroxy-3-oxopropionate reductase; 2-hydroxy-3-oxopropionate reductase 1449434..1450459 Actinosynnema mirum DSM 43827 8325491 YP_003099111.1 CDS Amir_1313 NC_013093.1 1450591 1451400 D KEGG: hypothetical protein; hypothetical protein 1450591..1451400 Actinosynnema mirum DSM 43827 8325492 YP_003099112.1 CDS Amir_1314 NC_013093.1 1451556 1452161 D PFAM: regulatory protein TetR; KEGG: mlo:mll3939 TetR family transcriptional regulator; TetR family transcriptional regulator 1451556..1452161 Actinosynnema mirum DSM 43827 8325493 YP_003099113.1 CDS Amir_1315 NC_013093.1 1452198 1453577 D PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0278 mercuric reductase, truncated; pyridine nucleotide-disulfide oxidoreductase dimerization region 1452198..1453577 Actinosynnema mirum DSM 43827 8325494 YP_003099114.1 CDS Amir_1316 NC_013093.1 1453946 1454317 D hypothetical protein 1453946..1454317 Actinosynnema mirum DSM 43827 8325495 YP_003099115.1 CDS Amir_1317 NC_013093.1 1454359 1455615 R KEGG: hypothetical protein; hypothetical protein complement(1454359..1455615) Actinosynnema mirum DSM 43827 8325496 YP_003099116.1 CDS Amir_1318 NC_013093.1 1455998 1456501 D hypothetical protein 1455998..1456501 Actinosynnema mirum DSM 43827 8325497 YP_003099117.1 CDS Amir_1319 NC_013093.1 1456796 1458490 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pzu:PHZ_c3203 ABC transporter, HlyB/MsbA family; ABC transporter complement(1456796..1458490) Actinosynnema mirum DSM 43827 8325498 YP_003099118.1 CDS Amir_1320 NC_013093.1 1458690 1460552 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pzu:PHZ_c3203 ABC transporter, HlyB/MsbA family; ABC transporter complement(1458690..1460552) Actinosynnema mirum DSM 43827 8325499 YP_003099119.1 CDS Amir_1321 NC_013093.1 1460697 1460852 R hypothetical protein complement(1460697..1460852) Actinosynnema mirum DSM 43827 8325500 YP_003099120.1 CDS Amir_1322 NC_013093.1 1460863 1463427 R PFAM: lanthionine synthetase C family protein; SMART: serine/threonine protein kinase; KEGG: smt:Smal_2130 serine/threonine protein kinase; serine/threonine protein kinase complement(1460863..1463427) Actinosynnema mirum DSM 43827 8325501 YP_003099121.1 CDS Amir_1323 NC_013093.1 1463858 1464514 D hypothetical protein 1463858..1464514 Actinosynnema mirum DSM 43827 8325502 YP_003099122.1 CDS Amir_1324 NC_013093.1 1464834 1466069 R PFAM: beta-ketoacyl synthase; KEGG: ade:Adeh_2746 3-oxoacyl-[acyl-carrier- protein] synthase II; beta-ketoacyl synthase complement(1464834..1466069) Actinosynnema mirum DSM 43827 8325503 YP_003099123.1 CDS acpP NC_013093.1 1466066 1466305 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(1466066..1466305) Actinosynnema mirum DSM 43827 8325504 YP_003099124.1 CDS Amir_1326 NC_013093.1 1466460 1467437 R KEGG: bha:BH2883 3-oxoacyl-(acyl carrier protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier- protein (ACP)] synthase III; 3-oxoacyl-(acyl-carrier-protein) synthase III complement(1466460..1467437) Actinosynnema mirum DSM 43827 8325505 YP_003099125.1 CDS Amir_1327 NC_013093.1 1467434 1468369 R PFAM: acyl transferase; KEGG: bvi:Bcep1808_1041 [acyl-carrier-protein] S- malonyltransferase; acyl transferase complement(1467434..1468369) Actinosynnema mirum DSM 43827 8325506 YP_003099126.1 CDS Amir_1328 NC_013093.1 1468569 1469750 R KEGG: reu:Reut_B5661 CdaR family transcriptional regulator; PucR family transcriptional regulator complement(1468569..1469750) Actinosynnema mirum DSM 43827 8325507 YP_003099127.1 CDS Amir_1329 NC_013093.1 1470123 1471016 D PFAM: Conserved hypothetical protein; KEGG: pfo:Pfl01_1775 TM helix protein; hypothetical protein 1470123..1471016 Actinosynnema mirum DSM 43827 8325508 YP_003099128.1 CDS Amir_1330 NC_013093.1 1471751 1472449 D TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: mpt:Mpe_A2849 transporter; nicotinamide mononucleotide transporter PnuC 1471751..1472449 Actinosynnema mirum DSM 43827 8325509 YP_003099129.1 CDS Amir_1331 NC_013093.1 1472436 1473782 R PFAM: extracellular solute-binding protein family 1; KEGG: mxa:MXAN_7295 sugar ABC transporter, periplasmic sugar-binding protein; family 1 extracellular solute-binding protein complement(1472436..1473782) Actinosynnema mirum DSM 43827 8325510 YP_003099130.1 CDS Amir_1332 NC_013093.1 1473772 1476027 R KEGG: hypothetical protein; hypothetical protein complement(1473772..1476027) Actinosynnema mirum DSM 43827 8325511 YP_003099131.1 CDS aceE NC_013093.1 1476231 1478990 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(1476231..1478990) Actinosynnema mirum DSM 43827 8325512 YP_003099132.1 CDS Amir_1334 NC_013093.1 1479123 1479224 D hypothetical protein 1479123..1479224 Actinosynnema mirum DSM 43827 8325513 YP_003099133.1 CDS Amir_1335 NC_013093.1 1479301 1479735 D KEGG: ccs:CCNA_02657 hypothetical protein; hypothetical protein 1479301..1479735 Actinosynnema mirum DSM 43827 8325514 YP_003099134.1 CDS Amir_1336 NC_013093.1 1479850 1480308 D PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pzu:PHZ_p0072 peroxiredoxin; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 1479850..1480308 Actinosynnema mirum DSM 43827 8325515 YP_003099135.1 CDS Amir_1337 NC_013093.1 1480601 1480843 R hypothetical protein complement(1480601..1480843) Actinosynnema mirum DSM 43827 8325517 YP_003099136.1 CDS Amir_1338 NC_013093.1 1481435 1481719 D hypothetical protein 1481435..1481719 Actinosynnema mirum DSM 43827 8325518 YP_003099137.1 CDS Amir_1339 NC_013093.1 1481994 1483025 D PFAM: saccharopine dehydrogenase; KEGG: pfl:PFL_3454 hypothetical protein; saccharopine dehydrogenase 1481994..1483025 Actinosynnema mirum DSM 43827 8325519 YP_003099138.1 CDS Amir_1340 NC_013093.1 1483000 1484004 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1483000..1484004) Actinosynnema mirum DSM 43827 8325520 YP_003099139.1 CDS Amir_1341 NC_013093.1 1484020 1484943 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bid:Bind_0032 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(1484020..1484943) Actinosynnema mirum DSM 43827 8325521 YP_003099140.1 CDS Amir_1342 NC_013093.1 1485131 1486066 D PFAM: luciferase-like monooxygenase; KEGG: rpi:Rpic_0157 luciferase-like monooxygenase; luciferase-like monooxygenase 1485131..1486066 Actinosynnema mirum DSM 43827 8325522 YP_003099141.1 CDS Amir_1343 NC_013093.1 1486216 1487214 R KEGG: afw:Anae109_3917 hypothetical protein; hypothetical protein complement(1486216..1487214) Actinosynnema mirum DSM 43827 8325523 YP_003099142.1 CDS Amir_1344 NC_013093.1 1487308 1488051 R TIGRFAM: lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase; KEGG: aba:Acid345_4305 lipoate-protein ligase B; lipoate-protein ligase B complement(1487308..1488051) Actinosynnema mirum DSM 43827 8325524 YP_003099143.1 CDS Amir_1345 NC_013093.1 1488048 1488896 R SMART: helix-turn-helix domain protein; KEGG: bxe:Bxe_B0902 XRE family transcriptional regulator; helix-turn-helix domain-containing protein complement(1488048..1488896) Actinosynnema mirum DSM 43827 8325525 YP_003099144.1 CDS Amir_1346 NC_013093.1 1488999 1489442 D KEGG: bsu:BSU06870 hypothetical protein; hypothetical protein 1488999..1489442 Actinosynnema mirum DSM 43827 8325526 YP_003099145.1 CDS Amir_1347 NC_013093.1 1489439 1490266 D PFAM: NmrA family protein; KEGG: scl:sce0707 hypothetical protein; NmrA family protein 1489439..1490266 Actinosynnema mirum DSM 43827 8325527 YP_003099146.1 CDS Amir_1348 NC_013093.1 1490263 1490886 R PFAM: phosphoesterase PA-phosphatase related; KEGG: ade:Adeh_2905 phosphoesterase, PA-phosphatase related; PA-phosphatase-like phosphodiesterase complement(1490263..1490886) Actinosynnema mirum DSM 43827 8325528 YP_003099147.1 CDS Amir_1349 NC_013093.1 1490886 1491779 R PFAM: domain of unknown function DUF1731; NAD- dependent epimerase/dehydratase; KEGG: dal:Dalk_2335 domain of unknown function DUF1731; hypothetical protein complement(1490886..1491779) Actinosynnema mirum DSM 43827 8325529 YP_003099148.1 CDS Amir_1350 NC_013093.1 1491949 1493670 R KEGG: aba:Acid345_4350 2-oxoglutarate dehydrogenase E2 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase complement(1491949..1493670) Actinosynnema mirum DSM 43827 8325530 YP_003099149.1 CDS Amir_1351 NC_013093.1 1493723 1495093 R E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1493723..1495093) Actinosynnema mirum DSM 43827 8325531 YP_003099150.1 CDS Amir_1352 NC_013093.1 1495271 1495594 D hypothetical protein 1495271..1495594 Actinosynnema mirum DSM 43827 8325532 YP_003099151.1 CDS Amir_1353 NC_013093.1 1495756 1496364 D KEGG: scl:sce9254 secreted protein; hypothetical protein 1495756..1496364 Actinosynnema mirum DSM 43827 8325533 YP_003099152.1 CDS Amir_1354 NC_013093.1 1496488 1497987 R PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: pst:PSPTO_1271 leucyl aminopeptidase; Leucyl aminopeptidase complement(1496488..1497987) Actinosynnema mirum DSM 43827 8325534 YP_003099153.1 CDS Amir_1355 NC_013093.1 1498190 1499425 D KEGG: bph:Bphy_0096 amino acid permease-associated region; hypothetical protein 1498190..1499425 Actinosynnema mirum DSM 43827 8325535 YP_003099154.1 CDS Amir_1356 NC_013093.1 1499443 1500546 D KEGG: swi:Swit_0778 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; branched-chain amino acid aminotransferase 1499443..1500546 Actinosynnema mirum DSM 43827 8325536 YP_003099155.1 CDS Amir_1357 NC_013093.1 1500607 1501320 R TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: pde:Pden_1566 cobalamin 5'-phosphate synthase; cobalamin 5'-phosphate synthase complement(1500607..1501320) Actinosynnema mirum DSM 43827 8325537 YP_003099156.1 CDS cobT NC_013093.1 1501352 1502389 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(1501352..1502389) Actinosynnema mirum DSM 43827 8325538 YP_003099157.1 CDS Amir_1359 NC_013093.1 1502386 1502928 R PFAM: cobalbumin biosynthesis protein; KEGG: bbt:BBta_3140 adenosylcobinamide kinase; cobalbumin biosynthesis protein complement(1502386..1502928) Actinosynnema mirum DSM 43827 8325539 YP_003099158.1 CDS Amir_1360 NC_013093.1 1503061 1504047 R PFAM: aldo/keto reductase; KEGG: mxa:MXAN_6482 oxidoreductase, aldo/keto reductase family; aldo/keto reductase complement(1503061..1504047) Actinosynnema mirum DSM 43827 8325540 YP_003099159.1 CDS Amir_1361 NC_013093.1 1504077 1504490 R hypothetical protein complement(1504077..1504490) Actinosynnema mirum DSM 43827 8325541 YP_003099160.1 CDS Amir_1362 NC_013093.1 1504478 1505191 R hypothetical protein complement(1504478..1505191) Actinosynnema mirum DSM 43827 8325542 YP_003099161.1 CDS Amir_1363 NC_013093.1 1505333 1505971 R hypothetical protein complement(1505333..1505971) Actinosynnema mirum DSM 43827 8325543 YP_003099162.1 CDS Amir_1364 NC_013093.1 1506376 1506750 D TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: bvi:Bcep1808_0647 iron-sulfur cluster insertion protein ErpA; iron-sulfur cluster assembly accessory protein 1506376..1506750 Actinosynnema mirum DSM 43827 8325544 YP_003099163.1 CDS Amir_1365 NC_013093.1 1506885 1507109 R hypothetical protein complement(1506885..1507109) Actinosynnema mirum DSM 43827 8325545 YP_003099164.1 CDS Amir_1366 NC_013093.1 1507373 1509301 R KEGG: bsu:BSU30540 asparagine synthetase; TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; asparagine synthase complement(1507373..1509301) Actinosynnema mirum DSM 43827 8325546 YP_003099165.1 CDS Amir_1367 NC_013093.1 1509507 1510442 D TIGRFAM: cytochrome C oxidase, subunit II; PFAM: cytochrome C oxidase subunit II; KEGG: aeh:Mlg_0293 cytochrome C oxidase, subunit II; cytochrome C oxidase, subunit II 1509507..1510442 Actinosynnema mirum DSM 43827 8325547 YP_003099166.1 CDS Amir_1368 NC_013093.1 1510453 1510869 D cytochrome C oxidase 1510453..1510869 Actinosynnema mirum DSM 43827 8325548 YP_003099167.1 CDS Amir_1369 NC_013093.1 1511336 1512055 R PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: gsu:GSU3116 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase complement(1511336..1512055) Actinosynnema mirum DSM 43827 8325549 YP_003099168.1 CDS Amir_1370 NC_013093.1 1512542 1513591 R KEGG: mno:Mnod_5575 anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; glycosyl transferase, family 3-like; anthranilate phosphoribosyltransferase complement(1512542..1513591) Actinosynnema mirum DSM 43827 8325550 YP_003099169.1 CDS Amir_1371 NC_013093.1 1513597 1514007 R KEGG: rpc:RPC_3025 two component transcriptional regulator; response regulator receiver protein complement(1513597..1514007) Actinosynnema mirum DSM 43827 8325551 YP_003099170.1 CDS Amir_1372 NC_013093.1 1514050 1514460 R hypothetical protein complement(1514050..1514460) Actinosynnema mirum DSM 43827 8325552 YP_003099171.1 CDS Amir_1373 NC_013093.1 1514534 1515148 D PFAM: cytochrome C oxidase subunit III; KEGG: nar:Saro_0918 cytochrome C oxidase, subunit III; cytochrome C oxidase subunit III 1514534..1515148 Actinosynnema mirum DSM 43827 8325553 YP_003099172.1 CDS Amir_1374 NC_013093.1 1515190 1516002 D PFAM: cytochrome C class I; KEGG: pne:Pnec_1360 cytochrome C oxidase, cbb3- type, subunit III; cytochrome C class I 1515190..1516002 Actinosynnema mirum DSM 43827 8325554 YP_003099173.1 CDS Amir_1375 NC_013093.1 1515999 1517123 D PFAM: Rieske [2Fe-2S] domain protein; KEGG: mpt:Mpe_A0364 Rieske iron-sulfur protein; Rieske (2Fe-2S) domain-containing protein 1515999..1517123 Actinosynnema mirum DSM 43827 8325555 YP_003099174.1 CDS Amir_1376 NC_013093.1 1517120 1518814 D PFAM: Cytochrome b/b6 domain; KEGG: hha:Hhal_2108 cytochrome b/b6, N-terminal domain; cytochrome b/b6 domain-containing protein 1517120..1518814 Actinosynnema mirum DSM 43827 8325556 YP_003099175.1 CDS Amir_1377 NC_013093.1 1518884 1519165 R PFAM: regulatory protein AsnC/Lrp family; KEGG: dps:DP0751 transcription regulator; AsnC family transcriptional regulator complement(1518884..1519165) Actinosynnema mirum DSM 43827 8325557 YP_003099176.1 CDS Amir_1378 NC_013093.1 1519203 1520939 R contains 3'-5'exonuclease domain; hypothetical protein complement(1519203..1520939) Actinosynnema mirum DSM 43827 8325558 YP_003099177.1 CDS Amir_1379 NC_013093.1 1520999 1522552 D PFAM: protein of unknown function DUF901; KEGG: ank:AnaeK_0136 methyltransferase type 11; hypothetical protein 1520999..1522552 Actinosynnema mirum DSM 43827 8325559 YP_003099178.1 CDS Amir_1380 NC_013093.1 1522952 1523983 D PFAM: NLP/P60 protein; KEGG: dvu:DVU1392 NLP/P60 family protein; NLP/P60 protein 1522952..1523983 Actinosynnema mirum DSM 43827 8325560 YP_003099179.1 CDS Amir_1381 NC_013093.1 1524106 1525338 D KEGG: ppd:Ppro_1566 hypothetical protein; hypothetical protein 1524106..1525338 Actinosynnema mirum DSM 43827 8325561 YP_003099180.1 CDS Amir_1382 NC_013093.1 1525550 1526680 D PFAM: glycosyl transferase group 1; KEGG: acr:Acry_1803 glycosyl transferase, group 1; group 1 glycosyl transferase 1525550..1526680 Actinosynnema mirum DSM 43827 8325562 YP_003099181.1 CDS Amir_1383 NC_013093.1 1526877 1528685 R PFAM: AMP-dependent synthetase and ligase; KEGG: acp:A2cp1_1619 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase complement(1526877..1528685) Actinosynnema mirum DSM 43827 8325563 YP_003099182.1 CDS Amir_1384 NC_013093.1 1528815 1529195 D hypothetical protein 1528815..1529195 Actinosynnema mirum DSM 43827 8325564 YP_003099183.1 CDS Amir_1385 NC_013093.1 1529207 1529995 D PFAM: metallophosphoesterase; KEGG: sit:TM1040_3062 metallophosphoesterase; metallophosphoesterase 1529207..1529995 Actinosynnema mirum DSM 43827 8325565 YP_003099184.1 CDS Amir_1386 NC_013093.1 1530023 1530457 D PFAM: cyclase/dehydrase; KEGG: acp:A2cp1_2307 cyclase/dehydrase; cyclase/dehydrase 1530023..1530457 Actinosynnema mirum DSM 43827 8325566 YP_003099185.1 CDS Amir_1387 NC_013093.1 1530454 1531674 D PFAM: anion-transporting ATPase; KEGG: bcz:BCZK0288 arsenite-transporting ATPase; Arsenite-transporting ATPase 1530454..1531674 Actinosynnema mirum DSM 43827 8325567 YP_003099186.1 CDS Amir_1388 NC_013093.1 1531671 1532081 D KEGG: scl:sce1096 cell wall surface anchor family protein; hypothetical protein 1531671..1532081 Actinosynnema mirum DSM 43827 8325568 YP_003099187.1 CDS Amir_1389 NC_013093.1 1532075 1533052 D PFAM: ROK family protein; KEGG: mlo:mlr7234 glucose kinase; ROK family protein 1532075..1533052 Actinosynnema mirum DSM 43827 8325569 YP_003099188.1 CDS Amir_1390 NC_013093.1 1533348 1534754 D PFAM: ATP-binding region ATPase domain protein; KEGG: predicted gene, 100042292; anti-sigma regulatory factor, serine/threonine protein kinase 1533348..1534754 Actinosynnema mirum DSM 43827 8325570 YP_003099189.1 CDS Amir_1391 NC_013093.1 1534787 1535266 R KEGG: EP2 procyclin; hypothetical protein complement(1534787..1535266) Actinosynnema mirum DSM 43827 8325571 YP_003099190.1 CDS Amir_1392 NC_013093.1 1535477 1536214 D PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 1535477..1536214 Actinosynnema mirum DSM 43827 8325572 YP_003099191.1 CDS Amir_1393 NC_013093.1 1536429 1536941 D KEGG: reu:Reut_C6145 hypothetical protein; hypothetical protein 1536429..1536941 Actinosynnema mirum DSM 43827 8325573 YP_003099192.1 CDS Amir_1394 NC_013093.1 1537014 1538054 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1537014..1538054 Actinosynnema mirum DSM 43827 8325574 YP_003099193.1 CDS Amir_1395 NC_013093.1 1538323 1539711 D KEGG: rce:RC1_0952 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; phospho-2-dehydro-3-deoxyheptonate aldolase 1538323..1539711 Actinosynnema mirum DSM 43827 8325575 YP_003099194.1 CDS Amir_1396 NC_013093.1 1539870 1542401 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; protein of unknown function RIO1; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: bha:BH2504 serine/threonine protein kinase; serine/threonine protein kinase with PASTA sensor(s) complement(1539870..1542401) Actinosynnema mirum DSM 43827 8325576 YP_003099195.1 CDS Amir_1397 NC_013093.1 1542650 1542988 D hypothetical protein 1542650..1542988 Actinosynnema mirum DSM 43827 8325577 YP_003099196.1 CDS Amir_1398 NC_013093.1 1543167 1544627 R KEGG: met:M446_4899 hypothetical protein; hypothetical protein complement(1543167..1544627) Actinosynnema mirum DSM 43827 8325578 YP_003099197.1 CDS Amir_1399 NC_013093.1 1545067 1546575 R TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0895 phytoene desaturase; phytoene desaturase complement(1545067..1546575) Actinosynnema mirum DSM 43827 8325579 YP_003099198.1 CDS Amir_1400 NC_013093.1 1546577 1547647 R PFAM: polyprenyl synthetase; KEGG: scl:sce4204 geranyltranstransferase; polyprenyl synthetase complement(1546577..1547647) Actinosynnema mirum DSM 43827 8325580 YP_003099199.1 CDS Amir_1401 NC_013093.1 1547753 1548643 D KEGG: acr:Acry_0219 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase 1547753..1548643 Actinosynnema mirum DSM 43827 8325581 YP_003099200.1 CDS Amir_1402 NC_013093.1 1548687 1549127 R TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: ade:Adeh_3128 alkylhydroperoxidase AhpD core; alkylhydroperoxidase like protein complement(1548687..1549127) Actinosynnema mirum DSM 43827 8325582 YP_003099201.1 CDS Amir_1403 NC_013093.1 1549188 1549841 R hypothetical protein complement(1549188..1549841) Actinosynnema mirum DSM 43827 8325583 YP_003099202.1 CDS Amir_1404 NC_013093.1 1550030 1551709 D PFAM: protein of unknown function DUF885; KEGG: scl:sce1630 hypothetical protein; hypothetical protein 1550030..1551709 Actinosynnema mirum DSM 43827 8325584 YP_003099203.1 CDS Amir_1405 NC_013093.1 1551911 1552534 D hypothetical protein 1551911..1552534 Actinosynnema mirum DSM 43827 8325585 YP_003099204.1 CDS Amir_1406 NC_013093.1 1552583 1553146 R PFAM: GCN5-related N-acetyltransferase; KEGG: bce:BC2347 acetyltransferase; GCN5-like N-acetyltransferase complement(1552583..1553146) Actinosynnema mirum DSM 43827 8325586 YP_003099205.1 CDS Amir_1407 NC_013093.1 1553143 1553646 R PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: bur:Bcep18194_A6310 YbaK/prolyl-tRNA synthetase like protein; YbaK/prolyl-tRNA synthetase associated protein complement(1553143..1553646) Actinosynnema mirum DSM 43827 8325587 YP_003099206.1 CDS Amir_1408 NC_013093.1 1553938 1554774 D PFAM: protein of unknown function DUF1503; hypothetical protein 1553938..1554774 Actinosynnema mirum DSM 43827 8325588 YP_003099207.1 CDS Amir_1409 NC_013093.1 1554930 1556525 R KEGG: vsp:VS_1778 hypothetical protein; hypothetical protein complement(1554930..1556525) Actinosynnema mirum DSM 43827 8325589 YP_003099208.1 CDS Amir_1410 NC_013093.1 1556601 1557017 D KEGG: rle:RL3033 hypothetical protein; hypothetical protein 1556601..1557017 Actinosynnema mirum DSM 43827 8325590 YP_003099209.1 CDS Amir_1411 NC_013093.1 1557326 1557964 D PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; KEGG: gme:Gmet_0062 GntR family transcriptional regulator; GntR family transcriptional regulator 1557326..1557964 Actinosynnema mirum DSM 43827 8325591 YP_003099210.1 CDS Amir_1412 NC_013093.1 1557966 1558961 D catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate; 1-aminocyclopropane-1-carboxylate deaminase 1557966..1558961 Actinosynnema mirum DSM 43827 8325592 YP_003099211.1 CDS Amir_1413 NC_013093.1 1559384 1564204 R PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; ATPase AAA; KEGG: scl:sce3970 ATP-dependent helicase; DEAD/H associated domain-containing protein complement(1559384..1564204) Actinosynnema mirum DSM 43827 8325593 YP_003099212.1 CDS Amir_1414 NC_013093.1 1564201 1564338 R hypothetical protein complement(1564201..1564338) Actinosynnema mirum DSM 43827 8325594 YP_003099213.1 CDS Amir_1415 NC_013093.1 1564506 1566479 D PFAM: Heat shock protein 70; KEGG: hha:Hhal_0145 heat shock protein 70; Heat shock protein 70 1564506..1566479 Actinosynnema mirum DSM 43827 8325595 YP_003099214.1 CDS Amir_1416 NC_013093.1 1566531 1567739 D PFAM: major facilitator superfamily MFS_1; KEGG: bca:BCE_1913 major facilitator superfamily protein; major facilitator superfamily protein 1566531..1567739 Actinosynnema mirum DSM 43827 8325596 YP_003099215.1 CDS Amir_1417 NC_013093.1 1567764 1567910 R hypothetical protein complement(1567764..1567910) Actinosynnema mirum DSM 43827 8325597 YP_003099216.1 CDS Amir_1418 NC_013093.1 1568054 1568248 D hypothetical protein 1568054..1568248 Actinosynnema mirum DSM 43827 8325598 YP_003099217.1 CDS Amir_1419 NC_013093.1 1568424 1569467 D KEGG: bha:BH2383 recombinase A; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: ATPase AAA; recA protein 1568424..1569467 Actinosynnema mirum DSM 43827 8325599 YP_003099218.1 CDS Amir_1420 NC_013093.1 1569572 1570075 D PFAM: regulatory protein RecX; KEGG: scl:sce0207 hypothetical protein; regulatory protein RecX 1569572..1570075 Actinosynnema mirum DSM 43827 8325600 YP_003099219.1 CDS Amir_1421 NC_013093.1 1570515 1571207 R KEGG: bsu:BSU25740 hypothetical protein; hypothetical protein complement(1570515..1571207) Actinosynnema mirum DSM 43827 8325601 YP_003099220.1 CDS Amir_1422 NC_013093.1 1571513 1572151 R KEGG: sil:SPO3031 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase/4- hydroxy-2-oxoglutarate aldolase complement(1571513..1572151) Actinosynnema mirum DSM 43827 8325602 YP_003099221.1 CDS Amir_1423 NC_013093.1 1572148 1574019 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1572148..1574019) Actinosynnema mirum DSM 43827 8325603 YP_003099222.1 CDS Amir_1424 NC_013093.1 1574245 1574538 D hypothetical protein 1574245..1574538 Actinosynnema mirum DSM 43827 8325604 YP_003099223.1 CDS Amir_1425 NC_013093.1 1575022 1575783 D KEGG: aba:Acid345_1383 integral membrane protein; integral membrane protein 1575022..1575783 Actinosynnema mirum DSM 43827 8325605 YP_003099224.1 CDS sdhA NC_013093.1 1575828 1577699 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1575828..1577699 Actinosynnema mirum DSM 43827 8325606 YP_003099225.1 CDS Amir_1427 NC_013093.1 1577701 1578450 D catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; fumarate reductase iron-sulfur subunit 1577701..1578450 Actinosynnema mirum DSM 43827 8325607 YP_003099226.1 CDS Amir_1428 NC_013093.1 1578402 1579256 R PFAM: ADP-ribosylation/Crystallin J1; KEGG: predicted protein; K05521 ADP- ribosylglycohydrolase; ADP-ribosylation/Crystallin J1 complement(1578402..1579256) Actinosynnema mirum DSM 43827 8325608 YP_003099227.1 CDS Amir_1429 NC_013093.1 1579290 1579418 R hypothetical protein complement(1579290..1579418) Actinosynnema mirum DSM 43827 8325609 YP_003099228.1 CDS Amir_1431 NC_013093.1 1580183 1583029 R catalyzes the reduction of ribonucleotides to deoxyribonucleotides; the rate-limiting step in dNTP synthesis; vitamin B12-dependent ribonucleotide reductase complement(1580183..1583029) Actinosynnema mirum DSM 43827 8325611 YP_003099229.1 CDS Amir_1432 NC_013093.1 1583151 1583606 R PFAM: ATP-cone domain protein; KEGG: mxa:MXAN_4765 hypothetical protein; ATP-cone domain-containing protein complement(1583151..1583606) Actinosynnema mirum DSM 43827 8325612 YP_003099230.1 CDS Amir_1433 NC_013093.1 1584009 1584506 R PFAM: peptidoglycan-binding LysM; KEGG: bpa:BPP0017 hypothetical protein; peptidoglycan-binding LysM complement(1584009..1584506) Actinosynnema mirum DSM 43827 8325613 YP_003099231.1 CDS Amir_1434 NC_013093.1 1584725 1585432 D KEGG: bha:BH2356 LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24 and S26 domain protein; SOS-response transcriptional repressor, LexA 1584725..1585432 Actinosynnema mirum DSM 43827 8325614 YP_003099232.1 CDS Amir_1435 NC_013093.1 1585456 1586544 R KEGG: scl:sce0154 hypothetical protein; hypothetical protein complement(1585456..1586544) Actinosynnema mirum DSM 43827 8325615 YP_003099233.1 CDS Amir_1436 NC_013093.1 1586571 1588013 R TIGRFAM: GTP-binding proten HflX; PFAM: GTP-binding protein HSR1-related; KEGG: GTP-binding family protein; K03665 GTP- binding protein HflX; GTP-binding proten HflX complement(1586571..1588013) Actinosynnema mirum DSM 43827 8325616 YP_003099234.1 CDS Amir_1437 NC_013093.1 1588056 1588544 R PFAM: regulatory protein ArsR; ArsR family transcriptional regulator complement(1588056..1588544) Actinosynnema mirum DSM 43827 8325617 YP_003099235.1 CDS Amir_1438 NC_013093.1 1588653 1589903 D PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_2815 major facilitator transporter; major facilitator superfamily protein 1588653..1589903 Actinosynnema mirum DSM 43827 8325618 YP_003099236.1 CDS Amir_1439 NC_013093.1 1589935 1590753 R KEGG: ade:Adeh_0570 diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; PFAM: diaminopimelate epimerase; diaminopimelate epimerase complement(1589935..1590753) Actinosynnema mirum DSM 43827 8325619 YP_003099237.1 CDS Amir_1440 NC_013093.1 1590764 1591666 R KEGG: bha:BH2366 tRNA delta(2)- isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1590764..1591666) Actinosynnema mirum DSM 43827 8325620 YP_003099238.1 CDS Amir_1441 NC_013093.1 1591663 1592394 R KEGG: ade:Adeh_1392 flagellar biosynthesis/type III secretory pathway protein-like; hypothetical protein complement(1591663..1592394) Actinosynnema mirum DSM 43827 8325621 YP_003099239.1 CDS Amir_1442 NC_013093.1 1592558 1593904 D PFAM: protein of unknown function DUF349; KEGG: pha:PSHAa1895 hypothetical protein; hypothetical protein 1592558..1593904 Actinosynnema mirum DSM 43827 8325622 YP_003099240.1 CDS Amir_1443 NC_013093.1 1593983 1594534 R KEGG: hypothetical protein; hypothetical protein complement(1593983..1594534) Actinosynnema mirum DSM 43827 8325623 YP_003099241.1 CDS Amir_1444 NC_013093.1 1594531 1596006 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(1594531..1596006) Actinosynnema mirum DSM 43827 8325624 YP_003099242.1 CDS Amir_1445 NC_013093.1 1596358 1597281 D TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: tmz:Tmz1t_0431 TRAP transporter solute receptor, TAXI family; TRAP transporter solute receptor, TAXI family 1596358..1597281 Actinosynnema mirum DSM 43827 8325625 YP_003099243.1 CDS Amir_1446 NC_013093.1 1597325 1598710 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pfl:PFL_3853 sensor histidine kinase; histidine kinase complement(1597325..1598710) Actinosynnema mirum DSM 43827 8325626 YP_003099244.1 CDS Amir_1447 NC_013093.1 1598711 1599379 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: tbd:Tbd_2791 two component transcriptional regulator; winged helix family two component transcriptional regulator complement(1598711..1599379) Actinosynnema mirum DSM 43827 8325627 YP_003099245.1 CDS Amir_1448 NC_013093.1 1599516 1600271 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pde:Pden_5082 ABC transporter; ABC transporter 1599516..1600271 Actinosynnema mirum DSM 43827 8325628 YP_003099246.1 CDS Amir_1449 NC_013093.1 1600339 1601226 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bce:BC0640 glutamine-binding protein; family 3 extracellular solute-binding protein 1600339..1601226 Actinosynnema mirum DSM 43827 8325629 YP_003099247.1 CDS Amir_1450 NC_013093.1 1601309 1601956 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bca:BCE_0709 amino acid ABC transporter, permease protein; polar amino acid ABC transporter, inner membrane subunit 1601309..1601956 Actinosynnema mirum DSM 43827 8325630 YP_003099248.1 CDS Amir_1451 NC_013093.1 1601953 1602825 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: aav:Aave_3754 polar amino acid ABC transporter, inner membrane subunit; polar amino acid ABC transporter, inner membrane subunit 1601953..1602825 Actinosynnema mirum DSM 43827 8325631 YP_003099249.1 CDS Amir_1452 NC_013093.1 1602925 1603734 D KEGG: psb:Psyr_0113 hypothetical protein; hypothetical protein 1602925..1603734 Actinosynnema mirum DSM 43827 8325632 YP_003099250.1 CDS Amir_1453 NC_013093.1 1603952 1604146 D hypothetical protein 1603952..1604146 Actinosynnema mirum DSM 43827 8325633 YP_003099251.1 CDS Amir_1454 NC_013093.1 1604497 1605021 R PFAM: protein of unknown function DUF1470; KEGG: xau:Xaut_0954 hypothetical protein; hypothetical protein complement(1604497..1605021) Actinosynnema mirum DSM 43827 8325634 YP_003099252.1 CDS Amir_1455 NC_013093.1 1605108 1605767 D KEGG: pde:Pden_0168 hypothetical protein; hypothetical protein 1605108..1605767 Actinosynnema mirum DSM 43827 8325635 YP_003099253.1 CDS Amir_1456 NC_013093.1 1605798 1606733 D KEGG: sus:Acid_4767 hypothetical protein; hypothetical protein 1605798..1606733 Actinosynnema mirum DSM 43827 8325636 YP_003099254.1 CDS Amir_1457 NC_013093.1 1606759 1607457 D PFAM: endonuclease V; KEGG: sde:Sde_3689 endonuclease V; deoxyribonuclease V 1606759..1607457 Actinosynnema mirum DSM 43827 8325637 YP_003099255.1 CDS Amir_1458 NC_013093.1 1607462 1608694 R PFAM: glycoside hydrolase family 4; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: sus:Acid_1925 glycoside hydrolase family protein; glycoside hydrolase family protein complement(1607462..1608694) Actinosynnema mirum DSM 43827 8325638 YP_003099256.1 CDS Amir_1459 NC_013093.1 1608714 1609712 R catalyzes the formation of inosine from adenosine; adenosine deaminase complement(1608714..1609712) Actinosynnema mirum DSM 43827 8325639 YP_003099257.1 CDS Amir_1460 NC_013093.1 1609839 1611662 D catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1609839..1611662 Actinosynnema mirum DSM 43827 8325640 YP_003099258.1 CDS Amir_1461 NC_013093.1 1611816 1612826 D KEGG: afw:Anae109_2566 H+transporting two-sector ATPase C (AC39) subunit; hypothetical protein 1611816..1612826 Actinosynnema mirum DSM 43827 8325641 YP_003099259.1 CDS Amir_1462 NC_013093.1 1613008 1615050 R PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: ade:Adeh_0114 peptidase S9, prolyl oligopeptidase; peptidase S9 prolyl oligopeptidase active site domain-containing protein complement(1613008..1615050) Actinosynnema mirum DSM 43827 8325642 YP_003099260.1 CDS Amir_1463 NC_013093.1 1615056 1616018 R TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; dTDP-4- dehydrorhamnose reductase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; KEGG: bha:BH1108 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase complement(1615056..1616018) Actinosynnema mirum DSM 43827 8325643 YP_003099261.1 CDS Amir_1464 NC_013093.1 1617156 1618340 R TIGRFAM: galactokinase; PFAM: GHMP kinase domain protein; GHMP kinase; KEGG: scl:sce2225 hypothetical protein; galactokinase complement(1617156..1618340) Actinosynnema mirum DSM 43827 8325644 YP_003099262.1 CDS Amir_1465 NC_013093.1 1618346 1619038 R PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; KEGG: sus:Acid_2178 DtxR family iron dependent repressor; iron (metal) dependent repressor, DtxR family complement(1618346..1619038) Actinosynnema mirum DSM 43827 8325645 YP_003099263.1 CDS Amir_1466 NC_013093.1 1619136 1619984 D PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: tbd:Tbd_2489 3-mercaptopyruvate sulfurtransferase; rhodanese domain-containing protein 1619136..1619984 Actinosynnema mirum DSM 43827 8325646 YP_003099264.1 CDS Amir_1467 NC_013093.1 1620356 1620988 R KEGG: scl:sce4324 hypothetical protein; hypothetical protein complement(1620356..1620988) Actinosynnema mirum DSM 43827 8325647 YP_003099265.1 CDS Amir_1468 NC_013093.1 1621190 1622383 D PFAM: histone deacetylase superfamily; KEGG: bha:BH3237 acetoin dehydrogenase; histone deacetylase superfamily 1621190..1622383 Actinosynnema mirum DSM 43827 8325648 YP_003099266.1 CDS Amir_1469 NC_013093.1 1622383 1625091 D PFAM: CoA-binding domain protein; GCN5-related N- acetyltransferase; KEGG: mgm:Mmc1_1098 CoA-binding domain protein; CoA-binding domain-containing protein 1622383..1625091 Actinosynnema mirum DSM 43827 8325649 YP_003099267.1 CDS Amir_1470 NC_013093.1 1625368 1626192 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: bsu:BSU27440 glutamine ABC transporter (glutamine-binding protein); family 3 extracellular solute-binding protein 1625368..1626192 Actinosynnema mirum DSM 43827 8325650 YP_003099268.1 CDS Amir_1471 NC_013093.1 1626252 1627025 D PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bha:BH3323 GntR family transcriptional regulator; GntR family transcriptional regulator 1626252..1627025 Actinosynnema mirum DSM 43827 8325651 YP_003099269.1 CDS Amir_1472 NC_013093.1 1627273 1627623 D hypothetical protein 1627273..1627623 Actinosynnema mirum DSM 43827 8325652 YP_003099270.1 CDS Amir_1473 NC_013093.1 1627903 1628613 R KEGG: aba:Acid345_3970 hypothetical protein; hypothetical protein complement(1627903..1628613) Actinosynnema mirum DSM 43827 8325653 YP_003099271.1 CDS Amir_1474 NC_013093.1 1628610 1629170 R KEGG: gbm:Gbem_2014 secreted protein; hypothetical protein complement(1628610..1629170) Actinosynnema mirum DSM 43827 8325654 YP_003099272.1 CDS Amir_1475 NC_013093.1 1629277 1630431 R PFAM: protein of unknown function UPF0027; KEGG: scl:sce1307 hypothetical protein; hypothetical protein complement(1629277..1630431) Actinosynnema mirum DSM 43827 8325655 YP_003099273.1 CDS Amir_1476 NC_013093.1 1630517 1631320 R PFAM: ABC transporter; KEGG: aeh:Mlg_2716 ABC transporter; ABC transporter complement(1630517..1631320) Actinosynnema mirum DSM 43827 8325656 YP_003099274.1 CDS Amir_1477 NC_013093.1 1631317 1632282 R KEGG: aeh:Mlg_2715 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; daunorubicin ABC transporter ATPase complement(1631317..1632282) Actinosynnema mirum DSM 43827 8325657 YP_003099275.1 CDS Amir_1478 NC_013093.1 1632374 1632802 D PFAM: GCN5-related N-acetyltransferase; KEGG: smt:Smal_2582 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 1632374..1632802 Actinosynnema mirum DSM 43827 8325658 YP_003099276.1 CDS Amir_1479 NC_013093.1 1632947 1633801 D hypothetical protein 1632947..1633801 Actinosynnema mirum DSM 43827 8325659 YP_003099277.1 CDS Amir_1480 NC_013093.1 1633798 1633977 D PFAM: protein of unknown function DUF397; hypothetical protein 1633798..1633977 Actinosynnema mirum DSM 43827 8325660 YP_003099278.1 CDS Amir_1481 NC_013093.1 1634388 1635326 R KEGG: ade:Adeh_2732 heat repeat-containing PBS lyase; hypothetical protein complement(1634388..1635326) Actinosynnema mirum DSM 43827 8325661 YP_003099279.1 CDS Amir_1482 NC_013093.1 1635407 1636330 R hypothetical protein complement(1635407..1636330) Actinosynnema mirum DSM 43827 8325662 YP_003099280.1 CDS Amir_1483 NC_013093.1 1637021 1638931 R KEGG: ade:Adeh_1681 PE-PGRS family protein; signal transduction protein with Nacht domain complement(1637021..1638931) Actinosynnema mirum DSM 43827 8325663 YP_003099281.1 CDS Amir_1484 NC_013093.1 1639091 1640584 R PFAM: Aldehyde Dehydrogenase; KEGG: ppw:PputW619_1998 aldehyde dehydrogenase; aldehyde dehydrogenase complement(1639091..1640584) Actinosynnema mirum DSM 43827 8325664 YP_003099282.1 CDS Amir_1485 NC_013093.1 1640581 1641405 R PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short- chain dehydrogenase/reductase SDR; KEGG: pst:PSPTO_1053 hypothetical protein; NAD-dependent epimerase/dehydratase complement(1640581..1641405) Actinosynnema mirum DSM 43827 8325665 YP_003099283.1 CDS Amir_1486 NC_013093.1 1641430 1642212 R PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: bpt:Bpet4676 IclR family transcriptional regulator; IclR family transcriptional regulator complement(1641430..1642212) Actinosynnema mirum DSM 43827 8325666 YP_003099284.1 CDS Amir_1487 NC_013093.1 1642464 1643456 D catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 1642464..1643456 Actinosynnema mirum DSM 43827 8325667 YP_003099285.1 CDS Amir_1488 NC_013093.1 1643453 1644709 D PFAM: mandelate racemase/muconate lactonizing protein; KEGG: hypothetical protein; K01706 glucarate dehydratase; mandelate racemase/muconate lactonizing protein 1643453..1644709 Actinosynnema mirum DSM 43827 8325668 YP_003099286.1 CDS Amir_1489 NC_013093.1 1644703 1645836 D KEGG: rle:pRL100423 hypothetical protein; hypothetical protein 1644703..1645836 Actinosynnema mirum DSM 43827 8325669 YP_003099287.1 CDS Amir_1490 NC_013093.1 1645887 1646390 D hypothetical protein 1645887..1646390 Actinosynnema mirum DSM 43827 8325670 YP_003099288.1 CDS Amir_1491 NC_013093.1 1646491 1647039 D KEGG: hypothetical protein; hypothetical protein 1646491..1647039 Actinosynnema mirum DSM 43827 8325671 YP_003099289.1 CDS Amir_1492 NC_013093.1 1647116 1648780 R TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: mxa:MXAN_3162 fumarate hydratase, class I; hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta complement(1647116..1648780) Actinosynnema mirum DSM 43827 8325672 YP_003099290.1 CDS Amir_1493 NC_013093.1 1649131 1650123 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase; RNA polymerase sigma factor SigB complement(1649131..1650123) Actinosynnema mirum DSM 43827 8325673 YP_003099291.1 CDS Amir_1494 NC_013093.1 1650344 1650769 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1650344..1650769) Actinosynnema mirum DSM 43827 8325674 YP_003099292.1 CDS Amir_1495 NC_013093.1 1650766 1652262 R PFAM: methyltransferase small; KEGG: sus:Acid_0229 methyltransferase small; methyltransferase small complement(1650766..1652262) Actinosynnema mirum DSM 43827 8325675 YP_003099293.1 CDS Amir_1496 NC_013093.1 1652363 1653871 R KEGG: bha:BH1072 hypothetical protein; PucR family transcriptional regulator complement(1652363..1653871) Actinosynnema mirum DSM 43827 8325676 YP_003099294.1 CDS Amir_1497 NC_013093.1 1653949 1654269 D hypothetical protein 1653949..1654269 Actinosynnema mirum DSM 43827 8325677 YP_003099295.1 CDS Amir_1498 NC_013093.1 1654251 1655153 R PFAM: PfkB domain protein; KEGG: oan:Oant_2477 PfkB domain protein; PfkB domain-containing protein complement(1654251..1655153) Actinosynnema mirum DSM 43827 8325678 YP_003099296.1 CDS Amir_1499 NC_013093.1 1655150 1656058 R PFAM: Indigoidine synthase A family protein; KEGG: swd:Swoo_1446 indigoidine synthase A family protein; Indigoidine synthase A family protein complement(1655150..1656058) Actinosynnema mirum DSM 43827 8325679 YP_003099297.1 CDS Amir_1500 NC_013093.1 1656090 1656335 D hypothetical protein 1656090..1656335 Actinosynnema mirum DSM 43827 8325680 YP_003099298.1 CDS Amir_1501 NC_013093.1 1656429 1657724 R PFAM: ribonuclease BN; KEGG: ppu:PP_4560 ribonuclease BN; ribonuclease BN complement(1656429..1657724) Actinosynnema mirum DSM 43827 8325681 YP_003099299.1 CDS Amir_1502 NC_013093.1 1657917 1659635 D PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; KEGG: sde:Sde_1925 GGDEF family protein; type III restriction protein res subunit 1657917..1659635 Actinosynnema mirum DSM 43827 8325682 YP_003099300.1 CDS Amir_1503 NC_013093.1 1660627 1661763 D KEGG: scl:sce6008 xylose binding protein transport system; Monosaccharide-transporting ATPase 1660627..1661763 Actinosynnema mirum DSM 43827 8325683 YP_003099301.1 CDS Amir_1504 NC_013093.1 1661861 1662634 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: acr:Acry_1972 ABC transporter; ABC transporter 1661861..1662634 Actinosynnema mirum DSM 43827 8325684 YP_003099302.1 CDS Amir_1505 NC_013093.1 1662634 1664124 D PFAM: inner-membrane translocator; KEGG: xylH; ABC transporter membrane spanning protein (xylose); inner-membrane translocator 1662634..1664124 Actinosynnema mirum DSM 43827 8325685 YP_003099303.1 CDS Amir_1506 NC_013093.1 1664126 1665298 D PFAM: ROK family protein; KEGG: bha:BH2758 transcriptional repressor of the xylose operon; ROK family protein 1664126..1665298 Actinosynnema mirum DSM 43827 8325686 YP_003099304.1 CDS Amir_1507 NC_013093.1 1665838 1666017 R hypothetical protein complement(1665838..1666017) Actinosynnema mirum DSM 43827 8325687 YP_003099305.1 CDS Amir_1508 NC_013093.1 1666546 1667103 D KEGG: NACA, TEBP; nascent polypeptide-associated complex alpha subunit; hypothetical protein 1666546..1667103 Actinosynnema mirum DSM 43827 8325688 YP_003099306.1 CDS Amir_1509 NC_013093.1 1667194 1668501 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor complement(1667194..1668501) Actinosynnema mirum DSM 43827 8325689 YP_003099307.1 CDS Amir_1510 NC_013093.1 1668710 1669471 R PFAM: ROK family protein; KEGG: asa:ASA_3376 ROK family protein; polyphosphate--glucose phosphotransferase complement(1668710..1669471) Actinosynnema mirum DSM 43827 8325690 YP_003099308.1 CDS Amir_1511 NC_013093.1 1669566 1670366 D PFAM: inositol monophosphatase; KEGG: noc:Noc_0719 inositol-1(or 4)-monophosphatase; inositol-phosphate phosphatase 1669566..1670366 Actinosynnema mirum DSM 43827 8325691 YP_003099309.1 CDS Amir_1512 NC_013093.1 1670839 1671546 R hypothetical protein complement(1670839..1671546) Actinosynnema mirum DSM 43827 8325692 YP_003099310.1 CDS Amir_1513 NC_013093.1 1671965 1672264 D hypothetical protein 1671965..1672264 Actinosynnema mirum DSM 43827 8325693 YP_003099311.1 CDS Amir_1514 NC_013093.1 1672857 1673381 R hypothetical protein complement(1672857..1673381) Actinosynnema mirum DSM 43827 8325694 YP_003099312.1 CDS Amir_1515 NC_013093.1 1673421 1673888 D KEGG: eli:ELI_10525 deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut 1673421..1673888 Actinosynnema mirum DSM 43827 8325695 YP_003099313.1 CDS Amir_1516 NC_013093.1 1673893 1674516 D hypothetical protein 1673893..1674516 Actinosynnema mirum DSM 43827 8325696 YP_003099314.1 CDS Amir_1517 NC_013093.1 1674570 1675340 R KEGG: mlo:mlr7232 hypothetical protein; hypothetical protein complement(1674570..1675340) Actinosynnema mirum DSM 43827 8325697 YP_003099315.1 CDS Amir_1518 NC_013093.1 1675453 1675830 D PFAM: nucleic acid binding OB-fold tRNA/helicase- type; OB-fold tRNA/helicase-type nucleic acid binding protein 1675453..1675830 Actinosynnema mirum DSM 43827 8325698 YP_003099316.1 CDS Amir_1519 NC_013093.1 1675827 1676645 D hypothetical protein 1675827..1676645 Actinosynnema mirum DSM 43827 8325699 YP_003099317.1 CDS Amir_1520 NC_013093.1 1676742 1677398 R PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rru:Rru_A1681 potassium transporter peripheral membrane component; TrkA-N domain-containing protein complement(1676742..1677398) Actinosynnema mirum DSM 43827 8325700 YP_003099318.1 CDS Amir_1521 NC_013093.1 1677398 1678060 R PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: asa:ASA_4143 potassium transporter peripheral membrane component; TrkA-N domain-containing protein complement(1677398..1678060) Actinosynnema mirum DSM 43827 8325701 YP_003099319.1 CDS Amir_1522 NC_013093.1 1678144 1680168 D KEGG: bcb:BCB4264_A1880 hypothetical protein; hypothetical protein 1678144..1680168 Actinosynnema mirum DSM 43827 8325702 YP_003099320.1 CDS Amir_1523 NC_013093.1 1680165 1681400 D PFAM: deoxyribonuclease/rho motif-related TRAM; (uracil-5)-methyltransferase; KEGG: sus:Acid_5841 23S rRNA (uracil-5-)- methyltransferase RumA; TRAM domain-containing protein 1680165..1681400 Actinosynnema mirum DSM 43827 8325703 YP_003099321.1 CDS Amir_1524 NC_013093.1 1681489 1683390 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1681489..1683390 Actinosynnema mirum DSM 43827 8325704 YP_003099322.1 CDS Amir_1525 NC_013093.1 1683607 1684311 D PFAM: hypothetical protein; KEGG: bja:bll5629 hypothetical protein; hypothetical protein 1683607..1684311 Actinosynnema mirum DSM 43827 8325705 YP_003099323.1 CDS Amir_1526 NC_013093.1 1684347 1685024 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: mca:MCA2330 DNA-binding response regulator; winged helix family two component transcriptional regulator 1684347..1685024 Actinosynnema mirum DSM 43827 8325706 YP_003099324.1 CDS Amir_1527 NC_013093.1 1685125 1686156 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sfu:Sfum_2006 integral membrane sensor signal transduction histidine kinase; histidine kinase 1685125..1686156 Actinosynnema mirum DSM 43827 8325707 YP_003099325.1 CDS Amir_1528 NC_013093.1 1691800 1691940 R hypothetical protein complement(1691800..1691940) Actinosynnema mirum DSM 43827 8325712 YP_003099326.1 CDS Amir_1529 NC_013093.1 1692143 1692736 R KEGG: scl:sce7642 hypothetical protein; hypothetical protein complement(1692143..1692736) Actinosynnema mirum DSM 43827 8325713 YP_003099327.1 CDS Amir_1530 NC_013093.1 1692780 1693151 R PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: azo:azo2136 hypothetical protein; MazG nucleotide pyrophosphohydrolase complement(1692780..1693151) Actinosynnema mirum DSM 43827 8325714 YP_003099328.1 CDS Amir_1531 NC_013093.1 1693176 1693940 R hypothetical protein complement(1693176..1693940) Actinosynnema mirum DSM 43827 8325715 YP_003099329.1 CDS Amir_1532 NC_013093.1 1693937 1695190 R KEGG: nha:Nham_3622 OmpA/MotB; hypothetical protein complement(1693937..1695190) Actinosynnema mirum DSM 43827 8325716 YP_003099330.1 CDS Amir_1533 NC_013093.1 1695187 1695621 R hypothetical protein complement(1695187..1695621) Actinosynnema mirum DSM 43827 8325717 YP_003099331.1 CDS Amir_1534 NC_013093.1 1695875 1696231 R hypothetical protein complement(1695875..1696231) Actinosynnema mirum DSM 43827 8325718 YP_003099332.1 CDS Amir_1535 NC_013093.1 1696432 1696773 R hypothetical protein complement(1696432..1696773) Actinosynnema mirum DSM 43827 8325719 YP_003099333.1 CDS Amir_1537 NC_013093.1 1697273 1697959 D KEGG: vvy:VV1763 hypothetical protein; hypothetical protein 1697273..1697959 Actinosynnema mirum DSM 43827 8325721 YP_003099334.1 CDS Amir_1538 NC_013093.1 1698000 1698764 R PFAM: protein of unknown function DUF72; KEGG: xac:XAC2920 hypothetical protein; hypothetical protein complement(1698000..1698764) Actinosynnema mirum DSM 43827 8325722 YP_003099335.1 CDS Amir_1539 NC_013093.1 1698813 1699097 D TIGRFAM: prevent-host-death family protein; KEGG: rlt:Rleg2_2735 prevent-host-death family protein; prevent-host-death family protein 1698813..1699097 Actinosynnema mirum DSM 43827 8325723 YP_003099336.1 CDS Amir_1540 NC_013093.1 1699085 1699498 D PFAM: PilT protein domain protein; KEGG: bcm:Bcenmc03_4257 PilT domain-containing protein; PilT protein domain-containing protein 1699085..1699498 Actinosynnema mirum DSM 43827 8325724 YP_003099337.1 CDS Amir_1541 NC_013093.1 1699569 1699970 R hypothetical protein complement(1699569..1699970) Actinosynnema mirum DSM 43827 8325725 YP_003099338.1 CDS Amir_1542 NC_013093.1 1700115 1701017 R PFAM: NAD-dependent epimerase/dehydratase; KEGG: ank:AnaeK_0030 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(1700115..1701017) Actinosynnema mirum DSM 43827 8325726 YP_003099339.1 CDS Amir_1543 NC_013093.1 1701157 1703268 R PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: sfu:Sfum_1404 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase complement(1701157..1703268) Actinosynnema mirum DSM 43827 8325727 YP_003099340.1 CDS Amir_1544 NC_013093.1 1703265 1704485 R KEGG: sfu:Sfum_1403 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase complement(1703265..1704485) Actinosynnema mirum DSM 43827 8325728 YP_003099341.1 CDS Amir_1545 NC_013093.1 1704572 1705021 R KEGG: scl:sce6782 hypothetical protein; hypothetical protein complement(1704572..1705021) Actinosynnema mirum DSM 43827 8325729 YP_003099342.1 CDS Amir_1546 NC_013093.1 1705018 1705938 R KEGG: scl:sce6783 hypothetical protein; hypothetical protein complement(1705018..1705938) Actinosynnema mirum DSM 43827 8325730 YP_003099343.1 CDS Amir_1547 NC_013093.1 1706023 1706742 D PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: smt:Smal_2399 transcriptional regulator, MerR family; MerR family transcriptional regulator 1706023..1706742 Actinosynnema mirum DSM 43827 8325731 YP_003099344.1 CDS Amir_1548 NC_013093.1 1707050 1708294 R PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein; KEGG: ade:Adeh_1602 3'-5' exonuclease; 3'-5' exonuclease complement(1707050..1708294) Actinosynnema mirum DSM 43827 8325732 YP_003099345.1 CDS Amir_1549 NC_013093.1 1708365 1709081 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: mfa:Mfla_0447 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator complement(1708365..1709081) Actinosynnema mirum DSM 43827 8325733 YP_003099346.1 CDS Amir_1550 NC_013093.1 1709337 1710503 D PFAM: peptidase M19 renal dipeptidase; KEGG: eli:ELI_09665 dipeptidase; membrane dipeptidase 1709337..1710503 Actinosynnema mirum DSM 43827 8325734 YP_003099347.1 CDS Amir_1551 NC_013093.1 1710712 1711260 R hypothetical protein complement(1710712..1711260) Actinosynnema mirum DSM 43827 8325735 YP_003099348.1 CDS Amir_1552 NC_013093.1 1711422 1712474 D KEGG: scl:sce8628 uroporphyrinogen decarboxylase; TIGRFAM: uroporphyrinogen decarboxylase; PFAM: uroporphyrinogen decarboxylase (URO-D); uroporphyrinogen decarboxylase 1711422..1712474 Actinosynnema mirum DSM 43827 8325736 YP_003099349.1 CDS Amir_1553 NC_013093.1 1712471 1713892 D KEGG: aba:Acid345_0695 protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; protoporphyrinogen oxidase 1712471..1713892 Actinosynnema mirum DSM 43827 8325737 YP_003099350.1 CDS Amir_1554 NC_013093.1 1713919 1714617 D PFAM: Chlorite dismutase; KEGG: bha:BH3825 heme peroxidase; Chlorite dismutase 1713919..1714617 Actinosynnema mirum DSM 43827 8325738 YP_003099351.1 CDS Amir_1555 NC_013093.1 1714673 1717909 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: shn:Shewana3_1740 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin complement(1714673..1717909) Actinosynnema mirum DSM 43827 8325739 YP_003099352.1 CDS Amir_1557 NC_013093.1 1721459 1721944 R hypothetical protein complement(1721459..1721944) Actinosynnema mirum DSM 43827 8325741 YP_003099353.1 CDS Amir_1558 NC_013093.1 1722016 1722375 R hypothetical protein complement(1722016..1722375) Actinosynnema mirum DSM 43827 8325742 YP_003099354.1 CDS Amir_1559 NC_013093.1 1722372 1723172 R PFAM: protein of unknown function DUF692; xylose isomerase; KEGG: scl:sce1885 hypothetical protein; hypothetical protein complement(1722372..1723172) Actinosynnema mirum DSM 43827 8325743 YP_003099355.1 CDS Amir_1560 NC_013093.1 1723198 1723977 R KEGG: hypothetical protein; hypothetical protein complement(1723198..1723977) Actinosynnema mirum DSM 43827 8325744 YP_003099356.1 CDS Amir_1561 NC_013093.1 1724008 1724307 R KEGG: scl:sce6895 hypothetical protein; hypothetical protein complement(1724008..1724307) Actinosynnema mirum DSM 43827 8325745 YP_003099357.1 CDS Amir_1562 NC_013093.1 1724383 1725249 R KEGG: erythrocyte membrane protein 1 (PfEMP1); hypothetical protein complement(1724383..1725249) Actinosynnema mirum DSM 43827 8325746 YP_003099358.1 CDS Amir_1563 NC_013093.1 1725221 1726132 R KEGG: hypothetical protein; hypothetical protein complement(1725221..1726132) Actinosynnema mirum DSM 43827 8325747 YP_003099359.1 CDS Amir_1564 NC_013093.1 1726173 1727093 R KEGG: met:M446_2019 hypothetical protein; hypothetical protein complement(1726173..1727093) Actinosynnema mirum DSM 43827 8325748 YP_003099360.1 CDS Amir_1565 NC_013093.1 1727353 1727781 R TIGRFAM: methionine-R-sulfoxide reductase; PFAM: methionine sulfoxide reductase B; KEGG: methionine-R-sulfoxide reductase SelR; methionine-R-sulfoxide reductase complement(1727353..1727781) Actinosynnema mirum DSM 43827 8325749 YP_003099361.1 CDS Amir_1566 NC_013093.1 1727881 1728195 R hypothetical protein complement(1727881..1728195) Actinosynnema mirum DSM 43827 8325750 YP_003099362.1 CDS Amir_1567 NC_013093.1 1728491 1729441 R PFAM: L-asparaginase II; KEGG: sil:SPO3349 L-asparaginase; L-asparaginase II complement(1728491..1729441) Actinosynnema mirum DSM 43827 8325751 YP_003099363.1 CDS Amir_1568 NC_013093.1 1729531 1730190 D PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pde:Pden_4617 transcriptional regulator, GntR family; GntR family transcriptional regulator 1729531..1730190 Actinosynnema mirum DSM 43827 8325752 YP_003099364.1 CDS Amir_1569 NC_013093.1 1730266 1731435 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bja:blr3304 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein complement(1730266..1731435) Actinosynnema mirum DSM 43827 8325753 YP_003099365.1 CDS Amir_1570 NC_013093.1 1731465 1732616 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: gur:Gura_3313 acyl-CoA dehydrogenase domain- containing protein; acyl-CoA dehydrogenase domain-containing protein complement(1731465..1732616) Actinosynnema mirum DSM 43827 8325754 YP_003099366.1 CDS Amir_1571 NC_013093.1 1732806 1733798 D TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: afw:Anae109_2830 DNA primase small subunit; DNA polymerase LigD, polymerase domain-containing protein 1732806..1733798 Actinosynnema mirum DSM 43827 8325755 YP_003099367.1 CDS Amir_1572 NC_013093.1 1733839 1734201 D hypothetical protein 1733839..1734201 Actinosynnema mirum DSM 43827 8325756 YP_003099368.1 CDS Amir_1573 NC_013093.1 1734198 1735178 R hypothetical protein complement(1734198..1735178) Actinosynnema mirum DSM 43827 8325757 YP_003099369.1 CDS Amir_1574 NC_013093.1 1735571 1736074 D KEGG: bpy:Bphyt_2395 haemagluttinin domain protein; hemaglutinin domain-containing protein 1735571..1736074 Actinosynnema mirum DSM 43827 8325758 YP_003099370.1 CDS Amir_1575 NC_013093.1 1736307 1736579 D hypothetical protein 1736307..1736579 Actinosynnema mirum DSM 43827 8325759 YP_003099371.1 CDS Amir_1576 NC_013093.1 1736832 1737497 D KEGG: mpt:Mpe_A1758 hypothetical protein; hypothetical protein 1736832..1737497 Actinosynnema mirum DSM 43827 8325760 YP_003099372.1 CDS Amir_1577 NC_013093.1 1738018 1739562 R PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: hypothetical protein; TAP domain-containing protein complement(1738018..1739562) Actinosynnema mirum DSM 43827 8325761 YP_003099373.1 CDS Amir_1578 NC_013093.1 1739653 1740558 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: mrd:Mrad2831_3085 hypothetical protein; hypothetical protein 1739653..1740558 Actinosynnema mirum DSM 43827 8325762 YP_003099374.1 CDS ligC NC_013093.1 1740560 1741636 R catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; ATP-dependent DNA ligase complement(1740560..1741636) Actinosynnema mirum DSM 43827 8325763 YP_003099375.1 CDS Amir_1580 NC_013093.1 1741688 1742476 R PFAM: bifunctional deaminase-reductase domain protein; KEGG: jan:Jann_3421 5-amino-6-(5- phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase; bifunctional deaminase-reductase domain-containing protein complement(1741688..1742476) Actinosynnema mirum DSM 43827 8325764 YP_003099376.1 CDS Amir_1581 NC_013093.1 1742475 1743482 D PFAM: AFG1-family ATPase; KEGG: shn:Shewana3_0691 AFG1 family ATPase; AFG1-family ATPase 1742475..1743482 Actinosynnema mirum DSM 43827 8325765 YP_003099377.1 CDS Amir_1582 NC_013093.1 1743552 1743797 D hypothetical protein 1743552..1743797 Actinosynnema mirum DSM 43827 8325766 YP_003099378.1 CDS Amir_1583 NC_013093.1 1743996 1745624 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ade:Adeh_0830 ABC transporter, duplicated ATPase subunits; ABC transporter 1743996..1745624 Actinosynnema mirum DSM 43827 8325767 YP_003099379.1 CDS Amir_1584 NC_013093.1 1745714 1746532 R KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein complement(1745714..1746532) Actinosynnema mirum DSM 43827 8325768 YP_003099380.1 CDS Amir_1585 NC_013093.1 1746582 1747619 R KEGG: sus:Acid_6335 hypothetical protein; hypothetical protein complement(1746582..1747619) Actinosynnema mirum DSM 43827 8325769 YP_003099381.1 CDS Amir_1586 NC_013093.1 1747848 1749077 D TIGRFAM: ornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: gbe:GbCGDNIH1_1948 ornithine--oxo-acid transaminase; ornithine aminotransferase 1747848..1749077 Actinosynnema mirum DSM 43827 8325770 YP_003099382.1 CDS Amir_1587 NC_013093.1 1749176 1750561 D KEGG: mrd:Mrad2831_2396 hypothetical protein; hypothetical protein 1749176..1750561 Actinosynnema mirum DSM 43827 8325771 YP_003099383.1 CDS Amir_1588 NC_013093.1 1750591 1751295 D PFAM: phosphoglycerate mutase; KEGG: xca:xccb100_3271 hypothetical protein; phosphoglycerate mutase 1750591..1751295 Actinosynnema mirum DSM 43827 8325772 YP_003099384.1 CDS Amir_1589 NC_013093.1 1751353 1752153 D KEGG: mxa:MXAN_0652 hypothetical protein; hypothetical protein 1751353..1752153 Actinosynnema mirum DSM 43827 8325773 YP_003099385.1 CDS Amir_1590 NC_013093.1 1752137 1752538 D KEGG: ank:AnaeK_1723 hypothetical protein; hypothetical protein 1752137..1752538 Actinosynnema mirum DSM 43827 8325774 YP_003099386.1 CDS Amir_1591 NC_013093.1 1752618 1753628 D TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bcz:BCZK4892 LytR family transcriptional regulator; cell envelope-related transcriptional attenuator 1752618..1753628 Actinosynnema mirum DSM 43827 8325775 YP_003099387.1 CDS Amir_1592 NC_013093.1 1753797 1754012 R hypothetical protein complement(1753797..1754012) Actinosynnema mirum DSM 43827 8325776 YP_003099388.1 CDS Amir_1593 NC_013093.1 1754516 1756726 D PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: hypothetical protein; PA-phosphatase-like phosphodiesterase 1754516..1756726 Actinosynnema mirum DSM 43827 8325777 YP_003099389.1 CDS Amir_1594 NC_013093.1 1757344 1757625 D hypothetical protein 1757344..1757625 Actinosynnema mirum DSM 43827 8325778 YP_003099390.1 CDS Amir_1595 NC_013093.1 1757786 1760104 R SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1757786..1760104) Actinosynnema mirum DSM 43827 8325779 YP_003099391.1 CDS Amir_1596 NC_013093.1 1760580 1760969 R KEGG: cak:Caul_3403 hypothetical protein; hypothetical protein complement(1760580..1760969) Actinosynnema mirum DSM 43827 8325780 YP_003099392.1 CDS Amir_1597 NC_013093.1 1761088 1761873 D PFAM: SpoOM family protein; Arrestin-like-like; KEGG: shm:Shewmr7_2729 SpoOM family protein; SpoOM family protein 1761088..1761873 Actinosynnema mirum DSM 43827 8325781 YP_003099393.1 CDS Amir_1598 NC_013093.1 1762055 1763200 D PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: pfo:Pfl01_4696 acyl-CoA dehydrogenase-like; acyl-CoA dehydrogenase domain-containing protein 1762055..1763200 Actinosynnema mirum DSM 43827 8325782 YP_003099394.1 CDS Amir_1599 NC_013093.1 1763290 1764486 D KEGG: dac:Daci_0764 hypothetical protein; hypothetical protein 1763290..1764486 Actinosynnema mirum DSM 43827 8325783 YP_003099395.1 CDS Amir_1600 NC_013093.1 1764483 1765928 D PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: dac:Daci_0766 von Willebrand factor type A; von Willebrand factor type A 1764483..1765928 Actinosynnema mirum DSM 43827 8325784 YP_003099396.1 CDS Amir_1601 NC_013093.1 1765915 1766673 D hypothetical protein 1765915..1766673 Actinosynnema mirum DSM 43827 8325785 YP_003099397.1 CDS Amir_1602 NC_013093.1 1766670 1767212 D PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: scl:sce4229 exonuclease; exonuclease RNase T and DNA polymerase III 1766670..1767212 Actinosynnema mirum DSM 43827 8325786 YP_003099398.1 CDS Amir_1603 NC_013093.1 1767241 1767810 D PFAM: regulatory protein TetR; KEGG: bph:Bphy_4824 TetR family transcriptional regulator; TetR family transcriptional regulator 1767241..1767810 Actinosynnema mirum DSM 43827 8325787 YP_003099399.1 CDS Amir_1604 NC_013093.1 1767873 1768445 R hypothetical protein complement(1767873..1768445) Actinosynnema mirum DSM 43827 8325788 YP_003099400.1 CDS Amir_1605 NC_013093.1 1768442 1768816 R hypothetical protein complement(1768442..1768816) Actinosynnema mirum DSM 43827 8325789 YP_003099401.1 CDS Amir_1606 NC_013093.1 1768937 1769398 R PFAM: MaoC domain protein dehydratase; KEGG: pol:Bpro_1240 MaoC-like dehydratase; MaoC domain-containing protein dehydratase complement(1768937..1769398) Actinosynnema mirum DSM 43827 8325790 YP_003099402.1 CDS Amir_1607 NC_013093.1 1769398 1770153 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bbr:BB0613 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(1769398..1770153) Actinosynnema mirum DSM 43827 8325791 YP_003099403.1 CDS Amir_1608 NC_013093.1 1770497 1771309 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pau:PA14_43180 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 1770497..1771309 Actinosynnema mirum DSM 43827 8325792 YP_003099404.1 CDS Amir_1609 NC_013093.1 1771309 1772265 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: qor; quinone oxidoreductase protein; alcohol dehydrogenase zinc-binding domain-containing protein 1771309..1772265 Actinosynnema mirum DSM 43827 8325793 YP_003099405.1 CDS Amir_1610 NC_013093.1 1772428 1772907 R KEGG: mucin-associated surface protein (MASP); mucin-associated surface protein complement(1772428..1772907) Actinosynnema mirum DSM 43827 8325794 YP_003099406.1 CDS Amir_1611 NC_013093.1 1773139 1774347 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: mno:Mnod_8803 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin complement(1773139..1774347) Actinosynnema mirum DSM 43827 8325795 YP_003099407.1 CDS Amir_1612 NC_013093.1 1774464 1775645 R PFAM: sodium/hydrogen exchanger; KEGG: bcb:BCB4264_A4853 sodium/hydrogen exchanger family protein; sodium/hydrogen exchanger complement(1774464..1775645) Actinosynnema mirum DSM 43827 8325796 YP_003099408.1 CDS Amir_1613 NC_013093.1 1775651 1776133 R PFAM: TrkA-C domain protein; KEGG: bcz:BCZK4776 potassium channel, C-terminus; TrkA-C domain-containing protein complement(1775651..1776133) Actinosynnema mirum DSM 43827 8325797 YP_003099409.1 CDS Amir_1614 NC_013093.1 1776789 1777508 D KEGG: gur:Gura_1465 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; cytidylate kinase 1776789..1777508 Actinosynnema mirum DSM 43827 8325798 YP_003099410.1 CDS Amir_1615 NC_013093.1 1777505 1778272 D PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: bha:BH1635 hypothetical protein; phospholipid/glycerol acyltransferase 1777505..1778272 Actinosynnema mirum DSM 43827 8325799 YP_003099411.1 CDS engA NC_013093.1 1778269 1779684 D synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1778269..1779684 Actinosynnema mirum DSM 43827 8325800 YP_003099412.1 CDS Amir_1617 NC_013093.1 1779726 1780370 D PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 1779726..1780370 Actinosynnema mirum DSM 43827 8325801 YP_003099413.1 CDS Amir_1618 NC_013093.1 1780367 1781476 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 1780367..1781476 Actinosynnema mirum DSM 43827 8325802 YP_003099414.1 CDS Amir_1619 NC_013093.1 1781757 1782734 D PFAM: integrase family protein; KEGG: scl:sce4427 site-specific recombinase; integrase family protein 1781757..1782734 Actinosynnema mirum DSM 43827 8325804 YP_003099415.1 CDS Amir_1620 NC_013093.1 1782731 1783006 D hypothetical protein 1782731..1783006 Actinosynnema mirum DSM 43827 8325805 YP_003099416.1 CDS Amir_1621 NC_013093.1 1783003 1783188 D hypothetical protein 1783003..1783188 Actinosynnema mirum DSM 43827 8325806 YP_003099417.1 CDS Amir_1622 NC_013093.1 1783232 1783483 D hypothetical protein 1783232..1783483 Actinosynnema mirum DSM 43827 8325807 YP_003099418.1 CDS Amir_1623 NC_013093.1 1783476 1783676 R hypothetical protein complement(1783476..1783676) Actinosynnema mirum DSM 43827 8325808 YP_003099419.1 CDS Amir_1624 NC_013093.1 1783747 1783950 R hypothetical protein complement(1783747..1783950) Actinosynnema mirum DSM 43827 8325809 YP_003099420.1 CDS Amir_1625 NC_013093.1 1783947 1784186 R hypothetical protein complement(1783947..1784186) Actinosynnema mirum DSM 43827 8325810 YP_003099421.1 CDS Amir_1626 NC_013093.1 1784770 1785558 D hypothetical protein 1784770..1785558 Actinosynnema mirum DSM 43827 8325811 YP_003099422.1 CDS Amir_1627 NC_013093.1 1785587 1785766 D PFAM: protein of unknown function DUF397; hypothetical protein 1785587..1785766 Actinosynnema mirum DSM 43827 8325812 YP_003099423.1 CDS Amir_1628 NC_013093.1 1785822 1786766 R hypothetical protein complement(1785822..1786766) Actinosynnema mirum DSM 43827 8325813 YP_003099424.1 CDS Amir_1629 NC_013093.1 1786791 1787978 R KEGG: bcr:BCAH187_A3991 phage minor structural protein, N-region; hypothetical protein complement(1786791..1787978) Actinosynnema mirum DSM 43827 8325814 YP_003099425.1 CDS Amir_1630 NC_013093.1 1787948 1788832 R hypothetical protein complement(1787948..1788832) Actinosynnema mirum DSM 43827 8325815 YP_003099426.1 CDS Amir_1631 NC_013093.1 1788825 1792739 R KEGG: mgm:Mmc1_2162 hypothetical protein; hypothetical protein complement(1788825..1792739) Actinosynnema mirum DSM 43827 8325816 YP_003099427.1 CDS Amir_1632 NC_013093.1 1792764 1792922 R hypothetical protein complement(1792764..1792922) Actinosynnema mirum DSM 43827 8325817 YP_003099428.1 CDS Amir_1633 NC_013093.1 1793009 1793488 R hypothetical protein complement(1793009..1793488) Actinosynnema mirum DSM 43827 8325818 YP_003099429.1 CDS Amir_1634 NC_013093.1 1793501 1793971 R hypothetical protein complement(1793501..1793971) Actinosynnema mirum DSM 43827 8325819 YP_003099430.1 CDS Amir_1635 NC_013093.1 1793968 1794432 R hypothetical protein complement(1793968..1794432) Actinosynnema mirum DSM 43827 8325820 YP_003099431.1 CDS Amir_1636 NC_013093.1 1794429 1794779 R hypothetical protein complement(1794429..1794779) Actinosynnema mirum DSM 43827 8325821 YP_003099432.1 CDS Amir_1637 NC_013093.1 1794779 1795099 R hypothetical protein complement(1794779..1795099) Actinosynnema mirum DSM 43827 8325822 YP_003099433.1 CDS Amir_1638 NC_013093.1 1795093 1795536 R KEGG: bpy:Bphyt_0835 hypothetical protein; hypothetical protein complement(1795093..1795536) Actinosynnema mirum DSM 43827 8325823 YP_003099434.1 CDS Amir_1639 NC_013093.1 1795533 1797497 R PFAM: lipolytic protein G-D-S-L family; KEGG: similar to hCG2041257; G-D-S-L family lipolytic protein complement(1795533..1797497) Actinosynnema mirum DSM 43827 8325824 YP_003099435.1 CDS Amir_1640 NC_013093.1 1797501 1797680 R hypothetical protein complement(1797501..1797680) Actinosynnema mirum DSM 43827 8325825 YP_003099436.1 CDS Amir_1641 NC_013093.1 1797677 1798336 R KEGG: mno:Mnod_2529 hypothetical protein; hypothetical protein complement(1797677..1798336) Actinosynnema mirum DSM 43827 8325826 YP_003099437.1 CDS Amir_1642 NC_013093.1 1798360 1798722 R hypothetical protein complement(1798360..1798722) Actinosynnema mirum DSM 43827 8325827 YP_003099438.1 CDS Amir_1643 NC_013093.1 1798715 1798969 R hypothetical protein complement(1798715..1798969) Actinosynnema mirum DSM 43827 8325828 YP_003099439.1 CDS Amir_1644 NC_013093.1 1799059 1799370 R hypothetical protein complement(1799059..1799370) Actinosynnema mirum DSM 43827 8325829 YP_003099440.1 CDS Amir_1645 NC_013093.1 1799372 1800592 R KEGG: bcr:BCAH187_A3735 hypothetical protein; hypothetical protein complement(1799372..1800592) Actinosynnema mirum DSM 43827 8325830 YP_003099441.1 CDS Amir_1646 NC_013093.1 1800706 1801410 R KEGG: azc:AZC_1123 hypothetical protein; hypothetical protein complement(1800706..1801410) Actinosynnema mirum DSM 43827 8325831 YP_003099442.1 CDS Amir_1647 NC_013093.1 1801435 1801707 R KEGG: nwi:Nwi_1556 hypothetical protein; hypothetical protein complement(1801435..1801707) Actinosynnema mirum DSM 43827 8325832 YP_003099443.1 CDS Amir_1648 NC_013093.1 1801731 1801940 R hypothetical protein complement(1801731..1801940) Actinosynnema mirum DSM 43827 8325833 YP_003099444.1 CDS Amir_1649 NC_013093.1 1802067 1802546 D hypothetical protein 1802067..1802546 Actinosynnema mirum DSM 43827 8325834 YP_003099445.1 CDS Amir_1650 NC_013093.1 1802599 1803663 R KEGG: ade:Adeh_2705 response regulator receiver; hypothetical protein complement(1802599..1803663) Actinosynnema mirum DSM 43827 8325835 YP_003099446.1 CDS Amir_1651 NC_013093.1 1803663 1805273 R hypothetical protein complement(1803663..1805273) Actinosynnema mirum DSM 43827 8325836 YP_003099447.1 CDS Amir_1652 NC_013093.1 1805405 1805812 D hypothetical protein 1805405..1805812 Actinosynnema mirum DSM 43827 8325837 YP_003099448.1 CDS Amir_1653 NC_013093.1 1805793 1807106 R TIGRFAM: phage terminase, large subunit, PBSX family; PFAM: protein of unknown function DUF264; phage terminase, large subunit, PBSX family complement(1805793..1807106) Actinosynnema mirum DSM 43827 8325838 YP_003099449.1 CDS Amir_1654 NC_013093.1 1807103 1807738 R hypothetical protein complement(1807103..1807738) Actinosynnema mirum DSM 43827 8325839 YP_003099450.1 CDS Amir_1655 NC_013093.1 1807990 1808364 R hypothetical protein complement(1807990..1808364) Actinosynnema mirum DSM 43827 8325840 YP_003099451.1 CDS Amir_1656 NC_013093.1 1808361 1808660 R KEGG: seg:SG1189 predicted phage regulatory protein; hypothetical protein complement(1808361..1808660) Actinosynnema mirum DSM 43827 8325841 YP_003099452.1 CDS Amir_1657 NC_013093.1 1808657 1809127 R hypothetical protein complement(1808657..1809127) Actinosynnema mirum DSM 43827 8325842 YP_003099453.1 CDS Amir_1658 NC_013093.1 1809139 1810431 R KEGG: ade:Adeh_1681 PE-PGRS family protein; PE-PGRS family protein complement(1809139..1810431) Actinosynnema mirum DSM 43827 8325843 YP_003099454.1 CDS Amir_1659 NC_013093.1 1810785 1811369 D PFAM: NUDIX hydrolase; KEGG: dar:Daro_0963 NUDIX hydrolase; NUDIX hydrolase 1810785..1811369 Actinosynnema mirum DSM 43827 8325844 YP_003099455.1 CDS Amir_1660 NC_013093.1 1811836 1812789 R hypothetical protein complement(1811836..1812789) Actinosynnema mirum DSM 43827 8325845 YP_003099456.1 CDS Amir_1661 NC_013093.1 1813199 1813957 D PFAM: MHYT domain protein; KEGG: sde:Sde_0524 integral membrane sensor protein; integral membrane sensor protein 1813199..1813957 Actinosynnema mirum DSM 43827 8325846 YP_003099457.1 CDS Amir_1662 NC_013093.1 1814020 1814577 D PFAM: ribonuclease H; KEGG: bte:BTH_I2790 RNase H; ribonuclease H 1814020..1814577 Actinosynnema mirum DSM 43827 8325847 YP_003099458.1 CDS Amir_1663 NC_013093.1 1814767 1815402 D KEGG: hypothetical protein; hypothetical protein 1814767..1815402 Actinosynnema mirum DSM 43827 8325848 YP_003099459.1 CDS Amir_1664 NC_013093.1 1815524 1817614 R KEGG: bcj:BCAM2418 haemagglutinin-related autotransporter protein; hypothetical protein complement(1815524..1817614) Actinosynnema mirum DSM 43827 8325849 YP_003099460.1 CDS Amir_1665 NC_013093.1 1817991 1819694 R KEGG: alpha-galactosidase, / melibiase, / alpha-D-galactoside galactohydrolase, ; K07407 alpha-galactosidase; PFAM: Ricin B lectin; glycoside hydrolase clan GH- D; SMART: Ricin B lectin; alpha-galactosidase complement(1817991..1819694) Actinosynnema mirum DSM 43827 8325850 YP_003099461.1 CDS Amir_1666 NC_013093.1 1820073 1821461 D SMART: helix-turn-helix domain protein; KEGG: scl:sce8759 hypothetical protein; XRE family transcriptional regulator 1820073..1821461 Actinosynnema mirum DSM 43827 8325851 YP_003099462.1 CDS Amir_1667 NC_013093.1 1821436 1821897 R hypothetical protein complement(1821436..1821897) Actinosynnema mirum DSM 43827 8325852 YP_003099463.1 CDS Amir_1668 NC_013093.1 1822290 1823048 D KEGG: msl:Msil_3349 hypothetical protein; hypothetical protein 1822290..1823048 Actinosynnema mirum DSM 43827 8325853 YP_003099464.1 CDS Amir_1669 NC_013093.1 1823045 1824178 D KEGG: mag:amb3212 periplasmic protein TonB, links inner and outer membranes; hypothetical protein 1823045..1824178 Actinosynnema mirum DSM 43827 8325854 YP_003099465.1 CDS Amir_1670 NC_013093.1 1824222 1824917 R KEGG: rso:RSc2037 ABC transporter ATP-binding protein; TIGRFAM: urea ABC transporter, ATP-binding protein UrtE; PFAM: ABC transporter; SMART: ATPase AAA; urea ABC transporter ATP-binding protein UrtE complement(1824222..1824917) Actinosynnema mirum DSM 43827 8325855 YP_003099466.1 CDS Amir_1671 NC_013093.1 1824917 1825663 R KEGG: scl:sce5582 ABC transporter ATP- binding protein; TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter; SMART: ATPase AAA; urea ABC transporter ATP-binding protein complement(1824917..1825663) Actinosynnema mirum DSM 43827 8325856 YP_003099467.1 CDS Amir_1672 NC_013093.1 1825660 1826838 R TIGRFAM: urea ABC transporter, permease protein UrtC; PFAM: inner-membrane translocator; KEGG: scl:sce5581 branched-chain amino acid ABC transporter, permease protein; urea ABC transporter permease complement(1825660..1826838) Actinosynnema mirum DSM 43827 8325857 YP_003099468.1 CDS Amir_1673 NC_013093.1 1826835 1827713 R TIGRFAM: urea ABC transporter, permease protein UrtB; PFAM: inner-membrane translocator; KEGG: scl:sce5580 branched-chain amino acid ABC transporter, permease protein; urea ABC transporter permease complement(1826835..1827713) Actinosynnema mirum DSM 43827 8325858 YP_003099469.1 CDS Amir_1674 NC_013093.1 1827715 1828938 R TIGRFAM: urea ABC transporter, urea binding protein; PFAM: Extracellular ligand-binding receptor; KEGG: scl:sce5579 branched-chain amino acid transport system substrate-binding protein; urea ABC transporter, urea binding protein complement(1827715..1828938) Actinosynnema mirum DSM 43827 8325859 YP_003099470.1 CDS Amir_1675 NC_013093.1 1829213 1830340 D PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: bha:BH0583 hypothetical protein; hypothetical protein 1829213..1830340 Actinosynnema mirum DSM 43827 8325860 YP_003099471.1 CDS Amir_1676 NC_013093.1 1830337 1832283 R KEGG: sde:Sde_0054 adenylyl cyclase class- 3/4/guanylyl cyclase; adenylyl cyclase class-3/4/guanylyl cyclase complement(1830337..1832283) Actinosynnema mirum DSM 43827 8325861 YP_003099472.1 CDS Amir_1677 NC_013093.1 1832382 1833689 R PFAM: ROK family protein; KEGG: rlt:Rleg2_2328 ROK family protein; ROK family protein complement(1832382..1833689) Actinosynnema mirum DSM 43827 8325862 YP_003099473.1 CDS Amir_1678 NC_013093.1 1833856 1835517 D PFAM: extracellular solute-binding protein family 5; KEGG: scl:sce8424 ABC-type dipeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 1833856..1835517 Actinosynnema mirum DSM 43827 8325863 YP_003099474.1 CDS Amir_1679 NC_013093.1 1835514 1836557 D KEGG: scl:sce4298 ABC-type oligopeptide transport system, ATPase component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 1835514..1836557 Actinosynnema mirum DSM 43827 8325864 YP_003099475.1 CDS Amir_1680 NC_013093.1 1836554 1837534 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce4301 peptide ABC transporter, permease protein; ABC transporter inner membrane protein 1836554..1837534 Actinosynnema mirum DSM 43827 8325865 YP_003099476.1 CDS Amir_1681 NC_013093.1 1837538 1838614 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sit:TM1040_2743 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 1837538..1838614 Actinosynnema mirum DSM 43827 8325866 YP_003099477.1 CDS Amir_1682 NC_013093.1 1838611 1839615 D KEGG: scl:sce4299 peptide ABC transporter, ATP- binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase subunit 1838611..1839615 Actinosynnema mirum DSM 43827 8325867 YP_003099478.1 CDS Amir_1683 NC_013093.1 1839636 1841039 D KEGG: rfr:Rfer_1102 beta-glucosidase; TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; beta-galactosidase 1839636..1841039 Actinosynnema mirum DSM 43827 8325868 YP_003099479.1 CDS Amir_1684 NC_013093.1 1841213 1842778 D KEGG: hypothetical protein LOC758923; hypothetical protein 1841213..1842778 Actinosynnema mirum DSM 43827 8325869 YP_003099480.1 CDS Amir_1685 NC_013093.1 1842769 1843434 D PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: cti:RALTA_A2171 serine/threonine protein phosphatase, P2C family; protein serine/threonine phosphatase 1842769..1843434 Actinosynnema mirum DSM 43827 8325870 YP_003099481.1 CDS Amir_1686 NC_013093.1 1843431 1843991 D hypothetical protein 1843431..1843991 Actinosynnema mirum DSM 43827 8325871 YP_003099482.1 CDS Amir_1687 NC_013093.1 1844064 1844288 D hypothetical protein 1844064..1844288 Actinosynnema mirum DSM 43827 8325872 YP_003099483.1 CDS Amir_1688 NC_013093.1 1844502 1844981 D PFAM: TspO/MBR family protein; KEGG: xca:xccb100_2086 peripheral-type benzodiazepine receptor; TspO and MBR like protein 1844502..1844981 Actinosynnema mirum DSM 43827 8325873 YP_003099484.1 CDS Amir_1689 NC_013093.1 1845119 1845670 D PFAM: protein of unknown function DUF664; hypothetical protein 1845119..1845670 Actinosynnema mirum DSM 43827 8325874 YP_003099485.1 CDS ruvB NC_013093.1 1845791 1846897 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1845791..1846897) Actinosynnema mirum DSM 43827 8325875 YP_003099486.1 CDS Amir_1691 NC_013093.1 1846894 1847490 R KEGG: ade:Adeh_0952 Holliday junction DNA helicase RuvA; TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; RuvA domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; Holliday junction DNA helicase RuvA complement(1846894..1847490) Actinosynnema mirum DSM 43827 8325876 YP_003099487.1 CDS Amir_1692 NC_013093.1 1847487 1848479 R KEGG: tgr:Tgr7_2236 crossover junction endodeoxyribonuclease; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; crossover junction endodeoxyribonuclease RuvC complement(1847487..1848479) Actinosynnema mirum DSM 43827 8325877 YP_003099488.1 CDS Amir_1693 NC_013093.1 1848685 1850268 D KEGG: dvm:DvMF_0211 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 1848685..1850268 Actinosynnema mirum DSM 43827 8325878 YP_003099489.1 CDS Amir_1694 NC_013093.1 1850628 1851029 D TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mag:amb2515 preprotein translocase subunit YajC; preprotein translocase subunit YajC 1850628..1851029 Actinosynnema mirum DSM 43827 8325879 YP_003099490.1 CDS Amir_1695 NC_013093.1 1851179 1853077 D TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: oca:OCAR_6254 protein-export membrane protein SecD; protein-export membrane protein SecD 1851179..1853077 Actinosynnema mirum DSM 43827 8325880 YP_003099491.1 CDS Amir_1696 NC_013093.1 1853079 1854269 D TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: cbc:CbuK_1009 protein translocase subunit; protein-export membrane protein SecF 1853079..1854269 Actinosynnema mirum DSM 43827 8325881 YP_003099492.1 CDS Amir_1697 NC_013093.1 1854293 1854784 D PFAM: phosphoribosyltransferase; KEGG: scl:sce2983 adenine phosphoribosyltransferase; adenine phosphoribosyltransferase 1854293..1854784 Actinosynnema mirum DSM 43827 8325882 YP_003099493.1 CDS Amir_1698 NC_013093.1 1854932 1857232 D KEGG: bha:BH1242 GTP pyrophosphokinase (stringent response); TIGRFAM: RelA/SpoT family protein; PFAM: RelA/SpoT domain protein; TGS domain protein; amino acid-binding ACT domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; (p)ppGpp synthetase I SpoT/RelA 1854932..1857232 Actinosynnema mirum DSM 43827 8325883 YP_003099494.1 CDS Amir_1699 NC_013093.1 1857403 1858248 R PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: hypothetical protein; K01802 peptidylprolyl isomerase; cyclophilin type peptidyl-prolyl cis-trans isomerase complement(1857403..1858248) Actinosynnema mirum DSM 43827 8325884 YP_003099495.1 CDS Amir_1700 NC_013093.1 1858464 1859168 D PFAM: beta-lactamase domain protein; KEGG: glo:Glov_3342 beta-lactamase domain protein; beta-lactamase domain-containing protein 1858464..1859168 Actinosynnema mirum DSM 43827 8325885 YP_003099496.1 CDS hisS NC_013093.1 1859178 1860443 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1859178..1860443 Actinosynnema mirum DSM 43827 8325886 YP_003099497.1 CDS Amir_1702 NC_013093.1 1860458 1861144 D hypothetical protein 1860458..1861144 Actinosynnema mirum DSM 43827 8325887 YP_003099498.1 CDS Amir_1703 NC_013093.1 1861201 1861602 R hypothetical protein complement(1861201..1861602) Actinosynnema mirum DSM 43827 8325888 YP_003099499.1 CDS Amir_1704 NC_013093.1 1862025 1862888 R KEGG: mxa:MXAN_2295 hypothetical protein; spermidine synthase-like protein complement(1862025..1862888) Actinosynnema mirum DSM 43827 8325889 YP_003099500.1 CDS Amir_1705 NC_013093.1 1862983 1863336 D PFAM: protein of unknown function DUF1304; KEGG: atc:AGR_L_3168 hypothetical protein; hypothetical protein 1862983..1863336 Actinosynnema mirum DSM 43827 8325890 YP_003099501.1 CDS Amir_1706 NC_013093.1 1863263 1864804 R PFAM: YibE/F family protein; KEGG: mgm:Mmc1_2300 YibE/F family protein; YibE/F family protein complement(1863263..1864804) Actinosynnema mirum DSM 43827 8325891 YP_003099502.1 CDS Amir_1707 NC_013093.1 1864829 1865713 D hypothetical protein 1864829..1865713 Actinosynnema mirum DSM 43827 8325892 YP_003099503.1 CDS Amir_1708 NC_013093.1 1865827 1866204 D KEGG: acp:A2cp1_3441 hypothetical protein; hypothetical protein 1865827..1866204 Actinosynnema mirum DSM 43827 8325893 YP_003099504.1 CDS Amir_1709 NC_013093.1 1866345 1866932 D PFAM: regulatory protein TetR; KEGG: mxa:MXAN_0079 transcriptional regulator, TetR family; TetR family transcriptional regulator 1866345..1866932 Actinosynnema mirum DSM 43827 8325894 YP_003099505.1 CDS Amir_1710 NC_013093.1 1867353 1868351 D KEGG: dal:Dalk_2661 wyosine base formation; hypothetical protein 1867353..1868351 Actinosynnema mirum DSM 43827 8325895 YP_003099506.1 CDS Amir_1712 NC_013093.1 1869963 1871558 D PFAM: carboxyl transferase; KEGG: ppu:PP_4065 propionyl-CoA carboxylase; propionyl-CoA carboxylase 1869963..1871558 Actinosynnema mirum DSM 43827 8325897 YP_003099507.1 CDS Amir_1713 NC_013093.1 1871566 1873596 D PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; protein of unknown function DUF201; biotin/lipoyl attachment domain- containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: bra:BRADO6875 biotin carboxylase; carbamoyl-phosphate synthase L chain ATP- binding 1871566..1873596 Actinosynnema mirum DSM 43827 8325898 YP_003099508.1 CDS Amir_1714 NC_013093.1 1873593 1874753 D PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bxe:Bxe_C0513 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 1873593..1874753 Actinosynnema mirum DSM 43827 8325899 YP_003099509.1 CDS Amir_1715 NC_013093.1 1874794 1875762 R KEGG: ccs:CCNA_00655 hypothetical protein; hypothetical protein complement(1874794..1875762) Actinosynnema mirum DSM 43827 8325900 YP_003099510.1 CDS Amir_1716 NC_013093.1 1876296 1876469 R hypothetical protein complement(1876296..1876469) Actinosynnema mirum DSM 43827 8325901 YP_003099511.1 CDS Amir_1717 NC_013093.1 1876598 1877743 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 1876598..1877743 Actinosynnema mirum DSM 43827 8325902 YP_003099512.1 CDS Amir_1718 NC_013093.1 1878010 1879203 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: swd:Swoo_2373 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 1878010..1879203 Actinosynnema mirum DSM 43827 8325903 YP_003099513.1 CDS aspS NC_013093.1 1879378 1881156 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1879378..1881156 Actinosynnema mirum DSM 43827 8325904 YP_003099514.1 CDS Amir_1720 NC_013093.1 1881662 1882846 D KEGG: lpp:plpp0130 hypothetical protein; hypothetical protein 1881662..1882846 Actinosynnema mirum DSM 43827 8325905 YP_003099515.1 CDS Amir_1721 NC_013093.1 1883100 1884374 R PFAM: glycosyl transferase family 2; GtrA family protein; KEGG: ppd:Ppro_2693 glycosyl transferase family protein; family 2 glycosyl transferase complement(1883100..1884374) Actinosynnema mirum DSM 43827 8325906 YP_003099516.1 CDS Amir_1722 NC_013093.1 1884413 1886338 R PFAM: glycosyl transferase family 39; KEGG: bsu:BSU12880 hypothetical protein; glycosyl transferase family protein complement(1884413..1886338) Actinosynnema mirum DSM 43827 8325907 YP_003099517.1 CDS Amir_1723 NC_013093.1 1886424 1887908 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sus:Acid_6896 heavy metal sensor signal transduction histidine kinase; histidine kinase complement(1886424..1887908) Actinosynnema mirum DSM 43827 8325908 YP_003099518.1 CDS Amir_1724 NC_013093.1 1887886 1888617 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bat:BAS2056 DNA-binding response regulator; winged helix family two component transcriptional regulator complement(1887886..1888617) Actinosynnema mirum DSM 43827 8325909 YP_003099519.1 CDS Amir_1725 NC_013093.1 1888831 1889538 D KEGG: bce:BC0440 surface protein; hypothetical protein 1888831..1889538 Actinosynnema mirum DSM 43827 8325910 YP_003099520.1 CDS Amir_1726 NC_013093.1 1889771 1890394 D PFAM: copper resistance protein CopC; KEGG: rpc:RPC_2426 copper resistance D; copper resistance protein CopC 1889771..1890394 Actinosynnema mirum DSM 43827 8325911 YP_003099521.1 CDS Amir_1727 NC_013093.1 1890678 1891280 D PFAM: uracil-DNA glycosylase; KEGG: scl:sce5098 G/U mismatch-specific DNA glycosylase; uracil-DNA glycosylase 1890678..1891280 Actinosynnema mirum DSM 43827 8325912 YP_003099522.1 CDS Amir_1728 NC_013093.1 1891218 1891976 R PFAM: protein of unknown function DUF742; KEGG: hypothetical protein; hypothetical protein complement(1891218..1891976) Actinosynnema mirum DSM 43827 8325913 YP_003099523.1 CDS Amir_1729 NC_013093.1 1892166 1892441 D PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: dps:DP2177 hypothetical protein; RNA-binding S4 domain-containing protein 1892166..1892441 Actinosynnema mirum DSM 43827 8325914 YP_003099524.1 CDS Amir_1730 NC_013093.1 1893873 1895276 D KEGG: ank:AnaeK_2858 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 1893873..1895276 Actinosynnema mirum DSM 43827 8325915 YP_003099525.1 CDS Amir_1731 NC_013093.1 1895276 1896370 D PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: ret:RHE_CH01364 oxidoreductase protein; oxidoreductase domain-containing protein 1895276..1896370 Actinosynnema mirum DSM 43827 8325916 YP_003099526.1 CDS Amir_1732 NC_013093.1 1896367 1896969 D KEGG: cvi:CV_4013 dTDP-6-deoxy-D-glucose-3,5 epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 1896367..1896969 Actinosynnema mirum DSM 43827 8325917 YP_003099527.1 CDS Amir_1733 NC_013093.1 1896966 1897940 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4- dehydrorhamnose reductase; short-chain dehydrogenase/reductase SDR; KEGG: rlt:Rleg2_6416 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 1896966..1897940 Actinosynnema mirum DSM 43827 8325918 YP_003099528.1 CDS Amir_1734 NC_013093.1 1897937 1899052 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mrd:Mrad2831_4616 DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 1897937..1899052 Actinosynnema mirum DSM 43827 8325919 YP_003099529.1 CDS Amir_1735 NC_013093.1 1899295 1904178 D KEGG: rle:pRL90161 hypothetical protein; hypothetical protein 1899295..1904178 Actinosynnema mirum DSM 43827 8325920 YP_003099530.1 CDS Amir_1736 NC_013093.1 1904193 1904849 D PFAM: transferase hexapeptide repeat containing protein; KEGG: acetyltransferase; transferase hexapeptide repeat containing protein 1904193..1904849 Actinosynnema mirum DSM 43827 8325921 YP_003099531.1 CDS Amir_1737 NC_013093.1 1904846 1905943 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: aba:Acid345_1081 DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 1904846..1905943 Actinosynnema mirum DSM 43827 8325922 YP_003099532.1 CDS Amir_1738 NC_013093.1 1905940 1906545 D KEGG: xcv:XCV3714 bifunctional isomerase / acetyl transferase; N-acetylglucosamine-1- phosphateuridyltransferase-like protein 1905940..1906545 Actinosynnema mirum DSM 43827 8325923 YP_003099533.1 CDS Amir_1739 NC_013093.1 1906676 1908073 R PFAM: O-antigen polymerase; KEGG: mxa:MXAN_3026 O-antigen polymerase family protein; O-antigen polymerase complement(1906676..1908073) Actinosynnema mirum DSM 43827 8325924 YP_003099534.1 CDS Amir_1740 NC_013093.1 1908073 1909209 R KEGG: dvu:DVU0508 translation initiation factor IF- 2; hypothetical protein complement(1908073..1909209) Actinosynnema mirum DSM 43827 8325925 YP_003099535.1 CDS Amir_1741 NC_013093.1 1909305 1910264 D KEGG: sus:Acid_4999 peptidase S9B dipeptidylpeptidase IV subunit; hypothetical protein 1909305..1910264 Actinosynnema mirum DSM 43827 8325926 YP_003099536.1 CDS Amir_1742 NC_013093.1 1910281 1910412 R hypothetical protein complement(1910281..1910412) Actinosynnema mirum DSM 43827 8325927 YP_003099537.1 CDS Amir_1743 NC_013093.1 1910513 1911733 R PFAM: transposase IS4 family protein; KEGG: rme:Rmet_4154 transposase, IS4 family; transposase IS4 family protein complement(1910513..1911733) Actinosynnema mirum DSM 43827 8325928 YP_003099538.1 CDS Amir_1744 NC_013093.1 1911891 1912421 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nar:Saro_3542 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1911891..1912421 Actinosynnema mirum DSM 43827 8325929 YP_003099539.1 CDS Amir_1745 NC_013093.1 1912915 1914135 R KEGG: smd:Smed_4803 glycosyl transferase group 1; group 1 glycosyl transferase complement(1912915..1914135) Actinosynnema mirum DSM 43827 8325930 YP_003099540.1 CDS Amir_1746 NC_013093.1 1914132 1915661 R PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; multi antimicrobial extrusion protein MatE; KEGG: pol:Bpro_1890 polysaccharide biosynthesis protein; polysaccharide biosynthesis protein complement(1914132..1915661) Actinosynnema mirum DSM 43827 8325931 YP_003099541.1 CDS Amir_1747 NC_013093.1 1915658 1916716 R PFAM: glycosyl transferase family 2; KEGG: smd:Smed_4802 glycosyl transferase family 2; family 2 glycosyl transferase complement(1915658..1916716) Actinosynnema mirum DSM 43827 8325932 YP_003099542.1 CDS Amir_1748 NC_013093.1 1916800 1917648 D KEGG: pat:Patl_2044 hypothetical protein; hypothetical protein 1916800..1917648 Actinosynnema mirum DSM 43827 8325933 YP_003099543.1 CDS Amir_1749 NC_013093.1 1917690 1918949 D KEGG: smd:Smed_4798 hypothetical protein; hypothetical protein 1917690..1918949 Actinosynnema mirum DSM 43827 8325934 YP_003099544.1 CDS Amir_1750 NC_013093.1 1919236 1920591 D TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein; KEGG: bca:BCE_2353 triple helix repeat-containing COllagen; 40-residue YVTN family beta-propeller repeat-containing protein 1919236..1920591 Actinosynnema mirum DSM 43827 8325935 YP_003099545.1 CDS Amir_1751 NC_013093.1 1921062 1922324 R PFAM: major facilitator superfamily MFS_1; KEGG: rce:RC1_3626 major facilitator superfamily transport protein; major facilitator superfamily protein complement(1921062..1922324) Actinosynnema mirum DSM 43827 8325936 YP_003099546.1 CDS Amir_1752 NC_013093.1 1922419 1923273 D TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: lch:Lcho_2341 WecB/TagA/CpsF family glycosyl transferase; WecB/TagA/CpsF family glycosyl transferase 1922419..1923273 Actinosynnema mirum DSM 43827 8325937 YP_003099547.1 CDS Amir_1753 NC_013093.1 1923276 1925393 D PFAM: glycosyl transferase family 2; KEGG: ank:AnaeK_2727 hypothetical protein; family 2 glycosyl transferase 1923276..1925393 Actinosynnema mirum DSM 43827 8325938 YP_003099548.1 CDS Amir_1754 NC_013093.1 1925587 1927194 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; protein of unknown function RIO1; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: tbd:Tbd_1700 serine/threonine protein kinase; serine/threonine protein kinase 1925587..1927194 Actinosynnema mirum DSM 43827 8325939 YP_003099549.1 CDS Amir_1755 NC_013093.1 1927409 1929025 D PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1927409..1929025 Actinosynnema mirum DSM 43827 8325940 YP_003099550.1 CDS Amir_1756 NC_013093.1 1929433 1930218 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bbt:BBta_2630 enoyl-CoA hydratase; Enoyl-CoA hydratase/isomerase complement(1929433..1930218) Actinosynnema mirum DSM 43827 8325941 YP_003099551.1 CDS Amir_1757 NC_013093.1 1930294 1930761 D PFAM: GCN5-related N-acetyltransferase; KEGG: met:M446_1745 MarR family transcriptional regulator; GCN5-like N-acetyltransferase 1930294..1930761 Actinosynnema mirum DSM 43827 8325942 YP_003099552.1 CDS Amir_1758 NC_013093.1 1930861 1931406 D PFAM: YCII-related; regulatory protein LuxR; Sigma- 70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: reu:Reut_B5221 YCII-related; LuxR family transcriptional regulator 1930861..1931406 Actinosynnema mirum DSM 43827 8325943 YP_003099553.1 CDS Amir_1759 NC_013093.1 1931594 1932055 D PFAM: thioesterase superfamily protein; KEGG: acp:A2cp1_3885 thioesterase superfamily protein; thioesterase superfamily protein 1931594..1932055 Actinosynnema mirum DSM 43827 8325944 YP_003099554.1 CDS Amir_1760 NC_013093.1 1932137 1932700 D hypothetical protein 1932137..1932700 Actinosynnema mirum DSM 43827 8325945 YP_003099555.1 CDS Amir_1761 NC_013093.1 1932807 1934399 R PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: scl:sce3770 phytoene dehydrogenase- related protein; amine oxidase complement(1932807..1934399) Actinosynnema mirum DSM 43827 8325946 YP_003099556.1 CDS Amir_1762 NC_013093.1 1934811 1937168 D PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; RNA binding S1 domain protein; KEGG: bja:bll7280 hypothetical protein; RNA binding S1 domain-containing protein 1934811..1937168 Actinosynnema mirum DSM 43827 8325947 YP_003099557.1 CDS Amir_1763 NC_013093.1 1937262 1938287 R PFAM: aldo/keto reductase; KEGG: rle:RL2983 aldo/keto reductase; aldo/keto reductase complement(1937262..1938287) Actinosynnema mirum DSM 43827 8325948 YP_003099558.1 CDS Amir_1764 NC_013093.1 1938464 1939318 D KEGG: rfr:Rfer_1474 hypothetical protein; hypothetical protein 1938464..1939318 Actinosynnema mirum DSM 43827 8325949 YP_003099559.1 CDS Amir_1765 NC_013093.1 1939422 1940177 D PFAM: Enoyl-CoA hydratase/isomerase; KEGG: nar:Saro_3457 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 1939422..1940177 Actinosynnema mirum DSM 43827 8325950 YP_003099560.1 CDS Amir_1766 NC_013093.1 1940174 1940764 R PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vei:Veis_4651 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase complement(1940174..1940764) Actinosynnema mirum DSM 43827 8325951 YP_003099561.1 CDS Amir_1767 NC_013093.1 1940928 1941077 R hypothetical protein complement(1940928..1941077) Actinosynnema mirum DSM 43827 8325952 YP_003099562.1 CDS Amir_1768 NC_013093.1 1941360 1941641 R KEGG: bmn:BMA10247_A2255 hypothetical protein; hypothetical protein complement(1941360..1941641) Actinosynnema mirum DSM 43827 8325953 YP_003099563.1 CDS Amir_1769 NC_013093.1 1941641 1943437 R KEGG: SNF2 superfamily protein; SNF2 superfamily protein complement(1941641..1943437) Actinosynnema mirum DSM 43827 8325954 YP_003099564.1 CDS Amir_1770 NC_013093.1 1943564 1944487 D PFAM: ribonuclease BN; KEGG: ppu:PP_4560 ribonuclease BN; ribonuclease BN 1943564..1944487 Actinosynnema mirum DSM 43827 8325955 YP_003099565.1 CDS Amir_1771 NC_013093.1 1944575 1945168 D KEGG: noc:Noc_1876 hypothetical protein; hypothetical protein 1944575..1945168 Actinosynnema mirum DSM 43827 8325956 YP_003099566.1 CDS Amir_1772 NC_013093.1 1945174 1946916 R PFAM: YheO domain protein; aminotransferase class V; KEGG: mxa:MXAN_1570 aminotransferase, class V; YheO domain-containing protein complement(1945174..1946916) Actinosynnema mirum DSM 43827 8325957 YP_003099567.1 CDS Amir_1773 NC_013093.1 1946919 1947677 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bac:BamMC406_6166 ABC transporter; ABC transporter complement(1946919..1947677) Actinosynnema mirum DSM 43827 8325958 YP_003099568.1 CDS Amir_1774 NC_013093.1 1947674 1948525 R TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_2097 ABC transporter permease; polar amino acid ABC transporter, inner membrane subunit complement(1947674..1948525) Actinosynnema mirum DSM 43827 8325959 YP_003099569.1 CDS Amir_1775 NC_013093.1 1948515 1949453 R PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: rle:RL0985 solute-binding component of ABC transporter; family 3 extracellular solute-binding protein complement(1948515..1949453) Actinosynnema mirum DSM 43827 8325960 YP_003099570.1 CDS Amir_1776 NC_013093.1 1949620 1950015 D TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: ank:AnaeK_2254 thioredoxin; thioredoxin 1949620..1950015 Actinosynnema mirum DSM 43827 8325961 YP_003099571.1 CDS Amir_1777 NC_013093.1 1950286 1950678 D PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 1950286..1950678 Actinosynnema mirum DSM 43827 8325962 YP_003099572.1 CDS Amir_1778 NC_013093.1 1950675 1951853 D KEGG: bch:Bcen2424_1675 precorrin-6y C5,15- methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15- methyltransferase (decarboxylating), CbiT subunit; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-6y C5,15-methyltransferase , CbiE subunit 1950675..1951853 Actinosynnema mirum DSM 43827 8325963 YP_003099573.1 CDS Amir_1779 NC_013093.1 1951850 1952602 D KEGG: bov:BOV_1262 precorrin-4 C11- methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-4 C11-methyltransferase 1951850..1952602 Actinosynnema mirum DSM 43827 8325964 YP_003099574.1 CDS Amir_1780 NC_013093.1 1952602 1953327 D KEGG: rru:Rru_A2988 precorrin-6A reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; precorrin-6x reductase 1952602..1953327 Actinosynnema mirum DSM 43827 8325965 YP_003099575.1 CDS Amir_1781 NC_013093.1 1953332 1954882 R TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: met:M446_2442 precorrin-3B C17- methyltransferase; precorrin-3B C17-methyltransferase complement(1953332..1954882) Actinosynnema mirum DSM 43827 8325966 YP_003099576.1 CDS Amir_1782 NC_013093.1 1954879 1955505 R PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: pmy:Pmen_4572 precorrin-8X methylmutase; Precorrin-8X methylmutase complement(1954879..1955505) Actinosynnema mirum DSM 43827 8325967 YP_003099577.1 CDS Amir_1783 NC_013093.1 1955502 1956539 R KEGG: bja:blr3264 hypothetical protein; hypothetical protein complement(1955502..1956539) Actinosynnema mirum DSM 43827 8325968 YP_003099578.1 CDS cobN NC_013093.1 1956717 1960298 D with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 1956717..1960298 Actinosynnema mirum DSM 43827 8325969 YP_003099579.1 CDS Amir_1785 NC_013093.1 1961227 1962501 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1924 sugar transport system (sugar- binding protein); family 1 extracellular solute-binding protein 1961227..1962501 Actinosynnema mirum DSM 43827 8325970 YP_003099580.1 CDS Amir_1786 NC_013093.1 1962498 1963505 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1925 sugar transport system (permease); ABC transporter inner membrane protein 1962498..1963505 Actinosynnema mirum DSM 43827 8325971 YP_003099581.1 CDS Amir_1787 NC_013093.1 1963509 1964327 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH1926 sugar transport system (permease); ABC transporter inner membrane protein 1963509..1964327 Actinosynnema mirum DSM 43827 8325972 YP_003099582.1 CDS Amir_1788 NC_013093.1 1964330 1965748 D KEGG: hch:HCH_06907 beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase; TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; beta-galactosidase 1964330..1965748 Actinosynnema mirum DSM 43827 8325973 YP_003099583.1 CDS Amir_1789 NC_013093.1 1965745 1966776 D KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 1965745..1966776 Actinosynnema mirum DSM 43827 8325974 YP_003099584.1 CDS Amir_1790 NC_013093.1 1966842 1967081 R TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: psp:PSPPH_B0015 prevent-host-death family protein; prevent-host-death family protein complement(1966842..1967081) Actinosynnema mirum DSM 43827 8325975 YP_003099585.1 CDS Amir_1791 NC_013093.1 1967594 1970335 D PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: cja:CJA_2477 endo-1,4-beta- glucanase/xyloglucanase, , gly74A; cellulose-binding family protein 1967594..1970335 Actinosynnema mirum DSM 43827 8325976 YP_003099586.1 CDS Amir_1792 NC_013093.1 1970531 1970758 R hypothetical protein complement(1970531..1970758) Actinosynnema mirum DSM 43827 8325977 YP_003099587.1 CDS Amir_1793 NC_013093.1 1971079 1973784 R PFAM: hypothetical protein; SMART: helix-turn-helix domain protein; hypothetical protein; KEGG: scl:sce5991 protein kinase; XRE family transcriptional regulator complement(1971079..1973784) Actinosynnema mirum DSM 43827 8325978 YP_003099588.1 CDS Amir_1794 NC_013093.1 1974385 1975533 R PFAM: ROK family protein; KEGG: acr:Acry_0116 ROK family protein; ROK family protein complement(1974385..1975533) Actinosynnema mirum DSM 43827 8325979 YP_003099589.1 CDS Amir_1795 NC_013093.1 1976134 1977273 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1976134..1977273 Actinosynnema mirum DSM 43827 8325980 YP_003099590.1 CDS Amir_1796 NC_013093.1 1977273 1978655 D TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: pen:PSEEN1988 xylulokinase; xylulokinase 1977273..1978655 Actinosynnema mirum DSM 43827 8325981 YP_003099591.1 CDS Amir_1797 NC_013093.1 1979137 1979373 R hypothetical protein complement(1979137..1979373) Actinosynnema mirum DSM 43827 8325982 YP_003099592.1 CDS Amir_1798 NC_013093.1 1979436 1980020 D KEGG: afw:Anae109_0147 hypothetical protein; hypothetical protein 1979436..1980020 Actinosynnema mirum DSM 43827 8325983 YP_003099593.1 CDS Amir_1799 NC_013093.1 1980017 1980271 D hypothetical protein 1980017..1980271 Actinosynnema mirum DSM 43827 8325984 YP_003099594.1 CDS Amir_1800 NC_013093.1 1980268 1981011 D PFAM: metallophosphoesterase; KEGG: mes:Meso_2768 metallophosphoesterase; metallophosphoesterase 1980268..1981011 Actinosynnema mirum DSM 43827 8325985 YP_003099595.1 CDS Amir_1801 NC_013093.1 1981090 1981707 R PFAM: cyclase/dehydrase; KEGG: mfa:Mfla_0007 cyclase/dehydrase; cyclase/dehydrase complement(1981090..1981707) Actinosynnema mirum DSM 43827 8325986 YP_003099596.1 CDS Amir_1802 NC_013093.1 1981969 1982829 D PFAM: transcription activator effector binding; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bsu:BSU05170 hypothetical protein; AraC family transcriptional regulator 1981969..1982829 Actinosynnema mirum DSM 43827 8325987 YP_003099597.1 CDS Amir_1803 NC_013093.1 1982881 1984059 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: mrd:Mrad2831_6253 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(1982881..1984059) Actinosynnema mirum DSM 43827 8325988 YP_003099598.1 CDS Amir_1804 NC_013093.1 1984174 1984575 R KEGG: azo:azo1781 hypothetical protein; hypothetical protein complement(1984174..1984575) Actinosynnema mirum DSM 43827 8325989 YP_003099599.1 CDS Amir_1805 NC_013093.1 1984628 1985140 R PFAM: transcriptional regulator domain protein; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator complement(1984628..1985140) Actinosynnema mirum DSM 43827 8325990 YP_003099600.1 CDS Amir_1806 NC_013093.1 1985515 1986342 D hypothetical protein 1985515..1986342 Actinosynnema mirum DSM 43827 8325991 YP_003099601.1 CDS Amir_1807 NC_013093.1 1986522 1987730 R PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_1009 sugar transport sugar binding protein; family 1 extracellular solute-binding protein complement(1986522..1987730) Actinosynnema mirum DSM 43827 8325992 YP_003099602.1 CDS Amir_1808 NC_013093.1 1988153 1990270 D KEGG: sus:Acid_1791 amino acid transporter; amino acid transporter 1988153..1990270 Actinosynnema mirum DSM 43827 8325993 YP_003099603.1 CDS Amir_1809 NC_013093.1 1990627 1992981 R PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; KEGG: mex:Mext_0562 kojibiose phosphorylase; Kojibiose phosphorylase complement(1990627..1992981) Actinosynnema mirum DSM 43827 8325994 YP_003099604.1 CDS Amir_1810 NC_013093.1 1992978 1993694 R TIGRFAM: beta-phosphoglucomutase family hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ajs:Ajs_2161 beta-phosphoglucomutase family hydrolase; beta-phosphoglucomutase family hydrolase complement(1992978..1993694) Actinosynnema mirum DSM 43827 8325995 YP_003099605.1 CDS Amir_1811 NC_013093.1 1993794 1995122 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rsh:Rsph17029_3442 cyclic nucleotide- regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1993794..1995122 Actinosynnema mirum DSM 43827 8325996 YP_003099606.1 CDS Amir_1812 NC_013093.1 1995162 1995482 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: mxa:MXAN_5617 transcriptional regulator, ArsR family; ArsR family transcriptional regulator complement(1995162..1995482) Actinosynnema mirum DSM 43827 8325997 YP_003099607.1 CDS Amir_1813 NC_013093.1 1995611 1996258 D hypothetical protein 1995611..1996258 Actinosynnema mirum DSM 43827 8325998 YP_003099608.1 CDS Amir_1814 NC_013093.1 1996298 1996621 D KEGG: PODXL2; podocalyxin-like 2; PODXL2; podocalyxin-like 2 1996298..1996621 Actinosynnema mirum DSM 43827 8325999 YP_003099609.1 CDS Amir_1815 NC_013093.1 1996849 1997349 D KEGG: rpi:Rpic_3996 alanine-rich signal peptide protein; hypothetical protein 1996849..1997349 Actinosynnema mirum DSM 43827 8326000 YP_003099610.1 CDS Amir_1816 NC_013093.1 1997398 1997685 R PFAM: transcription factor WhiB; transcription factor WhiB complement(1997398..1997685) Actinosynnema mirum DSM 43827 8326001 YP_003099611.1 CDS Amir_1817 NC_013093.1 1997743 1998606 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: scl:sce0579 MerR family transcriptional regulator; MerR family transcriptional regulator complement(1997743..1998606) Actinosynnema mirum DSM 43827 8326002 YP_003099612.1 CDS Amir_1818 NC_013093.1 1999168 1999902 D signal transduction histidine kinase 1999168..1999902 Actinosynnema mirum DSM 43827 8326003 YP_003099613.1 CDS Amir_1819 NC_013093.1 1999939 2000274 R TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: pde:Pden_0820 anti-sigma-factor antagonist; anti-sigma-factor antagonist complement(1999939..2000274) Actinosynnema mirum DSM 43827 8326004 YP_003099614.1 CDS Amir_1820 NC_013093.1 2000400 2001392 R PFAM: NLP/P60 protein; KEGG: dvu:DVU1392 NLP/P60 family protein; NLP/P60 protein complement(2000400..2001392) Actinosynnema mirum DSM 43827 8326005 YP_003099615.1 CDS Amir_1821 NC_013093.1 2001648 2002934 D KEGG: sit:TM1040_2323 hypothetical protein; hypothetical protein 2001648..2002934 Actinosynnema mirum DSM 43827 8326006 YP_003099616.1 CDS Amir_1822 NC_013093.1 2003094 2004383 D PFAM: chitin-binding domain 3 protein; Fibronectin type III domain protein; cellulose-binding family II; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: pag:PLES_44661 chitin-binding protein CbpD precursor; chitin-binding domain 3 protein 2003094..2004383 Actinosynnema mirum DSM 43827 8326007 YP_003099617.1 CDS Amir_1823 NC_013093.1 2004380 2004925 D hypothetical protein 2004380..2004925 Actinosynnema mirum DSM 43827 8326008 YP_003099618.1 CDS Amir_1824 NC_013093.1 2004936 2005979 R KEGG: yen:YE0107 DNA-binding transcriptional regulator CytR; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(2004936..2005979) Actinosynnema mirum DSM 43827 8326009 YP_003099619.1 CDS Amir_1825 NC_013093.1 2006247 2007287 D KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2006247..2007287 Actinosynnema mirum DSM 43827 8326010 YP_003099620.1 CDS Amir_1826 NC_013093.1 2007329 2009644 D PFAM: glycoside hydrolase family 3 domain protein; KEGG: esa:ESA_02100 hypothetical protein; glycoside hydrolase family protein 2007329..2009644 Actinosynnema mirum DSM 43827 8326011 YP_003099621.1 CDS Amir_1827 NC_013093.1 2009767 2010693 D hypothetical protein 2009767..2010693 Actinosynnema mirum DSM 43827 8326012 YP_003099622.1 CDS Amir_1828 NC_013093.1 2011077 2012039 R PFAM: acetyl xylan esterase; peptidase S15; KEGG: mlo:mlr6993 acetyl xylan esterase; acetyl xylan esterase complement(2011077..2012039) Actinosynnema mirum DSM 43827 8326013 YP_003099623.1 CDS Amir_1829 NC_013093.1 2012723 2012995 D hypothetical protein 2012723..2012995 Actinosynnema mirum DSM 43827 8326014 YP_003099624.1 CDS Amir_1830 NC_013093.1 2013242 2014873 D PFAM: glycoside hydrolase family 5; Fibronectin type III domain protein; cellulose-binding family II; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: sde:Sde_0064 secreted beta- mannosidase; glycoside hydrolase family protein 2013242..2014873 Actinosynnema mirum DSM 43827 8326015 YP_003099625.1 CDS Amir_1831 NC_013093.1 2014885 2016009 D PFAM: cellulose-binding family II; lipolytic protein G-D-S-L family; SMART: cellulose-binding family II; KEGG: hypothetical protein; cellulose-binding family protein 2014885..2016009 Actinosynnema mirum DSM 43827 8326016 YP_003099626.1 CDS Amir_1832 NC_013093.1 2016181 2016582 D PFAM: YCII-related; KEGG: scl:sce5148 hypothetical protein; YCII-like protein 2016181..2016582 Actinosynnema mirum DSM 43827 8326017 YP_003099627.1 CDS Amir_1833 NC_013093.1 2016750 2017862 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; KEGG: scl:sce5149 ECF subfamily RNA polymerase sigma-70 factor; RNA polymerase, sigma 70 family subunit 2016750..2017862 Actinosynnema mirum DSM 43827 8326018 YP_003099628.1 CDS Amir_1834 NC_013093.1 2018046 2018225 R PFAM: protein of unknown function DUF397; hypothetical protein complement(2018046..2018225) Actinosynnema mirum DSM 43827 8326019 YP_003099629.1 CDS Amir_1835 NC_013093.1 2018250 2019104 R SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein complement(2018250..2019104) Actinosynnema mirum DSM 43827 8326020 YP_003099630.1 CDS Amir_1836 NC_013093.1 2019292 2019525 D hypothetical protein 2019292..2019525 Actinosynnema mirum DSM 43827 8326021 YP_003099631.1 CDS Amir_1837 NC_013093.1 2019522 2020394 D SMART: helix-turn-helix domain protein; KEGG: hypothetical protein; helix-turn-helix domain-containing protein 2019522..2020394 Actinosynnema mirum DSM 43827 8326022 YP_003099632.1 CDS Amir_1838 NC_013093.1 2020504 2021010 R hypothetical protein complement(2020504..2021010) Actinosynnema mirum DSM 43827 8326023 YP_003099633.1 CDS Amir_1839 NC_013093.1 2021442 2023028 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: Foxred2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2021442..2023028 Actinosynnema mirum DSM 43827 8326024 YP_003099634.1 CDS Amir_1840 NC_013093.1 2023192 2025039 D KEGG: pca:Pcar_0512 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; Alkaline phosphatase 2023192..2025039 Actinosynnema mirum DSM 43827 8326025 YP_003099635.1 CDS Amir_1841 NC_013093.1 2025240 2026118 D KEGG: rsh:Rsph17029_3026 hypothetical protein; hypothetical protein 2025240..2026118 Actinosynnema mirum DSM 43827 8326026 YP_003099636.1 CDS Amir_1842 NC_013093.1 2026214 2027185 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bvi:Bcep1808_3829 LacI family transcription regulator; LacI family transcriptional regulator complement(2026214..2027185) Actinosynnema mirum DSM 43827 8326027 YP_003099637.1 CDS Amir_1843 NC_013093.1 2027491 2029683 D PFAM: pectate lyase/Amb allergen; pectinesterase; SMART: pectate lyase/Amb allergen; KEGG: bsu:BSU07560 pectate lyase; pectate lyase/Amb allergen 2027491..2029683 Actinosynnema mirum DSM 43827 8326028 YP_003099638.1 CDS Amir_1844 NC_013093.1 2029680 2030555 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smd:Smed_0187 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2029680..2030555 Actinosynnema mirum DSM 43827 8326029 YP_003099639.1 CDS Amir_1845 NC_013093.1 2030552 2031439 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smd:Smed_2422 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2030552..2031439 Actinosynnema mirum DSM 43827 8326030 YP_003099640.1 CDS Amir_1846 NC_013093.1 2031447 2032724 D PFAM: extracellular solute-binding protein family 1; KEGG: rle:pRL110364 substrate-binding component of ABC transporter; family 1 extracellular solute-binding protein 2031447..2032724 Actinosynnema mirum DSM 43827 8326031 YP_003099641.1 CDS Amir_1847 NC_013093.1 2032721 2033869 D PFAM: mandelate racemase/muconate lactonizing protein; KEGG: ent:Ent638_2707 mandelate racemase/muconate lactonizing protein; mandelate racemase/muconate lactonizing protein 2032721..2033869 Actinosynnema mirum DSM 43827 8326032 YP_003099642.1 CDS Amir_1848 NC_013093.1 2033980 2034933 D PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; Parallel beta- helix repeat; KEGG: pectate lyase; pectate lyase/Amb allergen 2033980..2034933 Actinosynnema mirum DSM 43827 8326033 YP_003099643.1 CDS Amir_1849 NC_013093.1 2035048 2036091 D PFAM: ketopantoate reductase ApbA/PanE domain protein; KEGG: gdi:GDI0989 2-dehydropantoate 2- reductase; ketopantoate reductase ApbA/PanE domain-containing protein 2035048..2036091 Actinosynnema mirum DSM 43827 8326034 YP_003099644.1 CDS Amir_1850 NC_013093.1 2036186 2037676 R PFAM: Ricin B lectin; peptidase alpha-lytic pro domain; peptidase S1 and S6 chymotrypsin/Hap; SMART: Ricin B lectin; KEGG: mxa:MXAN_5466 peptidase, S1E (streptogrisin A) subfamily; Ricin B lectin complement(2036186..2037676) Actinosynnema mirum DSM 43827 8326035 YP_003099645.1 CDS Amir_1851 NC_013093.1 2037830 2038228 R PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: dde:Dde_3083 glyoxalase family protein; glyoxalase/bleomycin resistance protein/dioxygenase complement(2037830..2038228) Actinosynnema mirum DSM 43827 8326036 YP_003099646.1 CDS Amir_1852 NC_013093.1 2038339 2039337 R PFAM: inner-membrane translocator; KEGG: aav:Aave_2249 inner membrane ABC transporter permease protein YjfF; Monosaccharide-transporting ATPase complement(2038339..2039337) Actinosynnema mirum DSM 43827 8326037 YP_003099647.1 CDS Amir_1853 NC_013093.1 2039334 2040305 R PFAM: inner-membrane translocator; KEGG: scl:sce3306 ribose/xylose/arabinose/galactoside ABC-type transporter permease; Monosaccharide-transporting ATPase complement(2039334..2040305) Actinosynnema mirum DSM 43827 8326038 YP_003099648.1 CDS Amir_1854 NC_013093.1 2040302 2041819 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bvi:Bcep1808_6551 ABC transporter; ABC transporter complement(2040302..2041819) Actinosynnema mirum DSM 43827 8326039 YP_003099649.1 CDS Amir_1855 NC_013093.1 2042023 2043003 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rpi:Rpic_4095 periplasmic binding protein/LacI transcriptional regulator; LacI family transcriptional regulator complement(2042023..2043003) Actinosynnema mirum DSM 43827 8326040 YP_003099650.1 CDS Amir_1856 NC_013093.1 2043266 2045485 D KEGG: hypothetical protein; hypothetical protein 2043266..2045485 Actinosynnema mirum DSM 43827 8326041 YP_003099651.1 CDS Amir_1857 NC_013093.1 2045592 2048072 D PFAM: alpha-L-arabinofuranosidase domain protein; carbohydrate-binding CenC domain protein; KEGG: ASD1; ASD1 (ALPHA-L-ARABINOFURANOSIDASE); hydrolase, acting on glycosyl bonds; alpha-N-arabinofuranosidase 2045592..2048072 Actinosynnema mirum DSM 43827 8326042 YP_003099652.1 CDS Amir_1858 NC_013093.1 2048069 2049586 D PFAM: glycoside hydrolase family 43; KEGG: hypothetical protein; alpha-N-arabinofuranosidase 2048069..2049586 Actinosynnema mirum DSM 43827 8326043 YP_003099653.1 CDS Amir_1859 NC_013093.1 2049583 2051793 D PFAM: protein of unknown function DUF1680; SMART: LamG domain protein jellyroll fold domain protein; KEGG: hypothetical protein; hypothetical protein 2049583..2051793 Actinosynnema mirum DSM 43827 8326044 YP_003099654.1 CDS Amir_1860 NC_013093.1 2051820 2052836 D KEGG: scl:sce3317 HTH-type transcriptional repressor PurR; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 2051820..2052836 Actinosynnema mirum DSM 43827 8326045 YP_003099655.1 CDS Amir_1861 NC_013093.1 2053322 2054986 D catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 2053322..2054986 Actinosynnema mirum DSM 43827 8326046 YP_003099656.1 CDS Amir_1862 NC_013093.1 2054989 2055642 D catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate; L-ribulose-5-phosphate 4-epimerase 2054989..2055642 Actinosynnema mirum DSM 43827 8326047 YP_003099657.1 CDS Amir_1863 NC_013093.1 2055663 2057171 D catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 2055663..2057171 Actinosynnema mirum DSM 43827 8326048 YP_003099658.1 CDS Amir_1864 NC_013093.1 2057334 2058455 D KEGG: rle:RL3617 solute-binding component of ABC transporter; ABC transporter solute-binding protein 2057334..2058455 Actinosynnema mirum DSM 43827 8326049 YP_003099659.1 CDS Amir_1865 NC_013093.1 2058458 2059984 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH3441 L-arabinose ABC transporter ATP- binding protein; ABC transporter 2058458..2059984 Actinosynnema mirum DSM 43827 8326050 YP_003099660.1 CDS Amir_1866 NC_013093.1 2059981 2061198 D PFAM: inner-membrane translocator; KEGG: bha:BH3440 L-arabinose ABC transporter (permease); inner-membrane translocator 2059981..2061198 Actinosynnema mirum DSM 43827 8326051 YP_003099661.1 CDS Amir_1867 NC_013093.1 2061252 2062469 D hypothetical protein 2061252..2062469 Actinosynnema mirum DSM 43827 8326052 YP_003099662.1 CDS Amir_1868 NC_013093.1 2062832 2065066 D PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: cja:CJA_3559 rhamnogalacturonan lyase, rgl11A; cellulose-binding family protein 2062832..2065066 Actinosynnema mirum DSM 43827 8326053 YP_003099663.1 CDS Amir_1869 NC_013093.1 2065200 2066354 D SMART: Parallel beta-helix repeat; KEGG: scl:sce5350 secreted protein; parallel beta-helix repeat-containing protein 2065200..2066354 Actinosynnema mirum DSM 43827 8326054 YP_003099664.1 CDS Amir_1870 NC_013093.1 2066451 2066780 R PFAM: Antibiotic biosynthesis monooxygenase; KEGG: rme:Rmet_5441 antibiotic biosynthesis monooxygenase; Antibiotic biosynthesis monooxygenase complement(2066451..2066780) Actinosynnema mirum DSM 43827 8326055 YP_003099665.1 CDS Amir_1871 NC_013093.1 2066879 2067880 R KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(2066879..2067880) Actinosynnema mirum DSM 43827 8326056 YP_003099666.1 CDS Amir_1872 NC_013093.1 2068096 2071038 D PFAM: alpha-L-arabinofuranosidase B; glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; KEGG: sus:Acid_6668 glycoside hydrolase family protein; alpha-L-arabinofuranosidase B 2068096..2071038 Actinosynnema mirum DSM 43827 8326057 YP_003099667.1 CDS Amir_1873 NC_013093.1 2071212 2074439 D TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; KEGG: sml:Smlt2180 hypothetical protein; alpha-1,2-mannosidase 2071212..2074439 Actinosynnema mirum DSM 43827 8326058 YP_003099668.1 CDS Amir_1874 NC_013093.1 2074586 2075710 D KEGG: scl:sce2753 protein kinase; hypothetical protein 2074586..2075710 Actinosynnema mirum DSM 43827 8326059 YP_003099669.1 CDS Amir_1875 NC_013093.1 2075861 2076955 R KEGG: dol:Dole_0415 filamentation induced by cAMP protein Fic; hypothetical protein complement(2075861..2076955) Actinosynnema mirum DSM 43827 8326060 YP_003099670.1 CDS Amir_1876 NC_013093.1 2076974 2077072 D hypothetical protein 2076974..2077072 Actinosynnema mirum DSM 43827 8326061 YP_003099671.1 CDS Amir_1877 NC_013093.1 2077405 2078571 D PFAM: endonuclease I; KEGG: bsu:BSU32540 hypothetical protein; endonuclease I 2077405..2078571 Actinosynnema mirum DSM 43827 8326062 YP_003099672.1 CDS Amir_1878 NC_013093.1 2078591 2078842 D KEGG: hypothetical protein LOC100078772; hypothetical protein 2078591..2078842 Actinosynnema mirum DSM 43827 8326063 YP_003099673.1 CDS Amir_1879 NC_013093.1 2078839 2079945 D PFAM: ATP-binding region ATPase domain protein; KEGG: vei:Veis_0031 multi-sensor signal transduction histidine kinase; signal transduction histidine kinase 2078839..2079945 Actinosynnema mirum DSM 43827 8326064 YP_003099674.1 CDS Amir_1880 NC_013093.1 2079938 2081032 D hypothetical protein 2079938..2081032 Actinosynnema mirum DSM 43827 8326065 YP_003099675.1 CDS Amir_1881 NC_013093.1 2081017 2081799 D PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: azo:azo0569 DNA-binding response regulator; LuxR family transcriptional regulator 2081017..2081799 Actinosynnema mirum DSM 43827 8326066 YP_003099676.1 CDS Amir_1882 NC_013093.1 2081952 2082611 D KEGG: YALI0F00990p; hypothetical protein 2081952..2082611 Actinosynnema mirum DSM 43827 8326067 YP_003099677.1 CDS Amir_1883 NC_013093.1 2082682 2083647 D KEGG: hch:HCH_00912 phosphoribosylpyrophosphate synthetase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; ribose-phosphate pyrophosphokinase 2082682..2083647 Actinosynnema mirum DSM 43827 8326068 YP_003099678.1 CDS Amir_1884 NC_013093.1 2083735 2085648 R PFAM: hypothetical protein; KEGG: mrd:Mrad2831_1392 zinc finger SWIM domain- containing protein; hypothetical protein complement(2083735..2085648) Actinosynnema mirum DSM 43827 8326069 YP_003099679.1 CDS Amir_1885 NC_013093.1 2085648 2086754 R PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor type A; KEGG: bur:Bcep18194_B1557 VWA containing CoxE-like protein; VWA containing CoxE family protein complement(2085648..2086754) Actinosynnema mirum DSM 43827 8326070 YP_003099680.1 CDS Amir_1886 NC_013093.1 2086751 2089204 R KEGG: bur:Bcep18194_B1556 hypothetical protein; hypothetical protein complement(2086751..2089204) Actinosynnema mirum DSM 43827 8326071 YP_003099681.1 CDS Amir_1887 NC_013093.1 2089204 2090295 R PFAM: ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: MoxR-like ATPase; ATPase complement(2089204..2090295) Actinosynnema mirum DSM 43827 8326072 YP_003099682.1 CDS Amir_1888 NC_013093.1 2090462 2093761 R KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein complement(2090462..2093761) Actinosynnema mirum DSM 43827 8326073 YP_003099683.1 CDS Amir_1889 NC_013093.1 2093898 2097158 R KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein complement(2093898..2097158) Actinosynnema mirum DSM 43827 8326074 YP_003099684.1 CDS Amir_1890 NC_013093.1 2097267 2100581 R KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein complement(2097267..2100581) Actinosynnema mirum DSM 43827 8326075 YP_003099685.1 CDS Amir_1891 NC_013093.1 2100738 2101886 R PFAM: glycosyl transferase group 1; KEGG: bpt:Bpet2351 glycosyltransferase; group 1 glycosyl transferase complement(2100738..2101886) Actinosynnema mirum DSM 43827 8326076 YP_003099686.1 CDS Amir_1892 NC_013093.1 2102119 2102532 D PFAM: OsmC family protein; KEGG: bch:Bcen2424_5605 OsmC family protein; OsmC family protein 2102119..2102532 Actinosynnema mirum DSM 43827 8326077 YP_003099687.1 CDS Amir_1893 NC_013093.1 2102730 2103701 R KEGG: hypothetical protein; hypothetical protein complement(2102730..2103701) Actinosynnema mirum DSM 43827 8326078 YP_003099688.1 CDS Amir_1894 NC_013093.1 2103775 2105016 R KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein complement(2103775..2105016) Actinosynnema mirum DSM 43827 8326079 YP_003099689.1 CDS Amir_1895 NC_013093.1 2105269 2106297 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: sme:SMc01159 oxidoreductase protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2105269..2106297 Actinosynnema mirum DSM 43827 8326080 YP_003099690.1 CDS Amir_1896 NC_013093.1 2106355 2107893 R PFAM: EPSP synthase (3-phosphoshikimate 1- carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bbt:BBta_0011 UDP-N-acetylglucosamine 1- carboxyvinyltransferase; XRE family transcriptional regulator complement(2106355..2107893) Actinosynnema mirum DSM 43827 8326081 YP_003099691.1 CDS Amir_1897 NC_013093.1 2108080 2108808 D hypothetical protein 2108080..2108808 Actinosynnema mirum DSM 43827 8326082 YP_003099692.1 CDS Amir_1898 NC_013093.1 2108796 2109224 D hypothetical protein 2108796..2109224 Actinosynnema mirum DSM 43827 8326083 YP_003099693.1 CDS Amir_1899 NC_013093.1 2109279 2110241 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 4 domain protein; KEGG: bha:BH1376 RNA polymerase sigma factor RpoD; RpoD subfamily RNA polymerase sigma-70 subunit complement(2109279..2110241) Actinosynnema mirum DSM 43827 8326084 YP_003099694.1 CDS Amir_1900 NC_013093.1 2110370 2111356 R PFAM: protein of unknown function DUF344; KEGG: tgr:Tgr7_0141 hypothetical protein; hypothetical protein complement(2110370..2111356) Actinosynnema mirum DSM 43827 8326085 YP_003099695.1 CDS Amir_1901 NC_013093.1 2111525 2111797 D PFAM: transglycosylase-associated protein; KEGG: csa:Csal_2587 transglycosylase-associated protein; transglycosylase-associated protein 2111525..2111797 Actinosynnema mirum DSM 43827 8326086 YP_003099696.1 CDS Amir_1902 NC_013093.1 2111981 2112085 D hypothetical protein 2111981..2112085 Actinosynnema mirum DSM 43827 8326087 YP_003099697.1 CDS Amir_1903 NC_013093.1 2112206 2112868 R KEGG: hch:HCH_06998 hypothetical protein; hypothetical protein complement(2112206..2112868) Actinosynnema mirum DSM 43827 8326088 YP_003099698.1 CDS Amir_1904 NC_013093.1 2112879 2113637 R KEGG: acp:A2cp1_0343 hypothetical protein; hypothetical protein complement(2112879..2113637) Actinosynnema mirum DSM 43827 8326089 YP_003099699.1 CDS Amir_1905 NC_013093.1 2113793 2114803 D PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: sal:Sala_2455 alcohol dehydrogenase GroES- like protein; alcohol dehydrogenase GroES domain-containing protein 2113793..2114803 Actinosynnema mirum DSM 43827 8326090 YP_003099700.1 CDS Amir_1906 NC_013093.1 2114951 2116000 R PFAM: nitroreductase; KEGG: afw:Anae109_0827 hypothetical protein; nitroreductase complement(2114951..2116000) Actinosynnema mirum DSM 43827 8326091 YP_003099701.1 CDS Amir_1907 NC_013093.1 2116138 2117838 D PFAM: GAF domain protein; histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: scl:sce2236 two-component system sensor kinase; GAF sensor signal transduction histidine kinase 2116138..2117838 Actinosynnema mirum DSM 43827 8326092 YP_003099702.1 CDS Amir_1908 NC_013093.1 2117835 2118002 D hypothetical protein 2117835..2118002 Actinosynnema mirum DSM 43827 8326093 YP_003099703.1 CDS Amir_1909 NC_013093.1 2117999 2118235 D hypothetical protein 2117999..2118235 Actinosynnema mirum DSM 43827 8326094 YP_003099704.1 CDS Amir_1910 NC_013093.1 2118365 2119021 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: bcy:Bcer98_0214 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator complement(2118365..2119021) Actinosynnema mirum DSM 43827 8326095 YP_003099705.1 CDS Amir_1911 NC_013093.1 2119273 2119698 D PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: pau:PA14_40540 CBS domain-containing protein; signal transduction protein with CBS domains 2119273..2119698 Actinosynnema mirum DSM 43827 8326096 YP_003099706.1 CDS Amir_1912 NC_013093.1 2119914 2120381 D PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 2119914..2120381 Actinosynnema mirum DSM 43827 8326097 YP_003099707.1 CDS Amir_1913 NC_013093.1 2120378 2122936 D PFAM: CoA-binding domain protein; GCN5-related N- acetyltransferase; KEGG: mgm:Mmc1_1098 CoA-binding domain protein; CoA-binding domain-containing protein 2120378..2122936 Actinosynnema mirum DSM 43827 8326098 YP_003099708.1 CDS Amir_1914 NC_013093.1 2122933 2123304 D KEGG: aeh:Mlg_0315 UspA domain-containing protein; UspA domain-containing protein 2122933..2123304 Actinosynnema mirum DSM 43827 8326099 YP_003099709.1 CDS Amir_1915 NC_013093.1 2123369 2123767 D KEGG: bbt:BBta_6725 hypothetical protein; hypothetical protein 2123369..2123767 Actinosynnema mirum DSM 43827 8326100 YP_003099710.1 CDS Amir_1916 NC_013093.1 2123894 2124190 R hypothetical protein complement(2123894..2124190) Actinosynnema mirum DSM 43827 8326101 YP_003099711.1 CDS Amir_1917 NC_013093.1 2124401 2125387 R PFAM: nitroreductase; KEGG: rce:RC1_3281 hypothetical protein; nitroreductase complement(2124401..2125387) Actinosynnema mirum DSM 43827 8326102 YP_003099712.1 CDS Amir_1918 NC_013093.1 2125566 2127935 D PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: bja:bll2518 phosphoketolase; phosphoketolase 2125566..2127935 Actinosynnema mirum DSM 43827 8326103 YP_003099713.1 CDS Amir_1919 NC_013093.1 2127935 2129020 D TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: nwi:Nwi_1948 acetate kinase; acetate kinase 2127935..2129020 Actinosynnema mirum DSM 43827 8326104 YP_003099714.1 CDS Amir_1920 NC_013093.1 2129898 2130914 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: scl:sce5315 protein kinase; serine/threonine protein kinase 2129898..2130914 Actinosynnema mirum DSM 43827 8326105 YP_003099715.1 CDS Amir_1921 NC_013093.1 2131354 2131851 D hypothetical protein 2131354..2131851 Actinosynnema mirum DSM 43827 8326106 YP_003099716.1 CDS Amir_1922 NC_013093.1 2132284 2134341 D PFAM: acyltransferase 3; KEGG: mes:Meso_0485 acyltransferase 3; acyltransferase 3 2132284..2134341 Actinosynnema mirum DSM 43827 8326107 YP_003099717.1 CDS Amir_1923 NC_013093.1 2134527 2135327 D PFAM: glycosyl transferase family 2; KEGG: ppd:Ppro_2693 glycosyl transferase family protein; family 2 glycosyl transferase 2134527..2135327 Actinosynnema mirum DSM 43827 8326108 YP_003099718.1 CDS Amir_1924 NC_013093.1 2135399 2137411 D PFAM: glycosyl transferase family 39; KEGG: bsu:BSU40490 hypothetical protein; glycosyl transferase family protein 2135399..2137411 Actinosynnema mirum DSM 43827 8326109 YP_003099719.1 CDS Amir_1925 NC_013093.1 2137527 2138777 D hypothetical protein 2137527..2138777 Actinosynnema mirum DSM 43827 8326110 YP_003099720.1 CDS Amir_1926 NC_013093.1 2138797 2139831 R KEGG: pen:PSEEN1955 ribose operon repressor RbsR; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(2138797..2139831) Actinosynnema mirum DSM 43827 8326111 YP_003099721.1 CDS Amir_1927 NC_013093.1 2140041 2141360 D PFAM: extracellular solute-binding protein family 1; KEGG: sugar ABC transporter; K10188 lactose/L- arabinose transport system substrate-binding protein; family 1 extracellular solute-binding protein 2140041..2141360 Actinosynnema mirum DSM 43827 8326112 YP_003099722.1 CDS Amir_1928 NC_013093.1 2141357 2142253 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K10189 lactose/L- arabinose transport system permease protein; ABC transporter inner membrane protein 2141357..2142253 Actinosynnema mirum DSM 43827 8326113 YP_003099723.1 CDS Amir_1929 NC_013093.1 2142250 2143092 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sml:Smlt3250 sugar transporter, permease protein; ABC transporter inner membrane protein 2142250..2143092 Actinosynnema mirum DSM 43827 8326114 YP_003099724.1 CDS Amir_1930 NC_013093.1 2143103 2144605 D PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: vei:Veis_3457 alpha-N-arabinofuranosidase; alpha-N-arabinofuranosidase 2143103..2144605 Actinosynnema mirum DSM 43827 8326115 YP_003099725.1 CDS Amir_1931 NC_013093.1 2145028 2145930 R PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; dTDP-4-dehydrorhamnose reductase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: glo:Glov_0487 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(2145028..2145930) Actinosynnema mirum DSM 43827 8326116 YP_003099726.1 CDS Amir_1932 NC_013093.1 2146023 2146454 R PFAM: cyclase/dehydrase; cyclase/dehydrase complement(2146023..2146454) Actinosynnema mirum DSM 43827 8326117 YP_003099727.1 CDS Amir_1933 NC_013093.1 2146634 2147359 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcb:BCB4264_A5589 DNA-binding response regulator YycF; winged helix family two component transcriptional regulator complement(2146634..2147359) Actinosynnema mirum DSM 43827 8326118 YP_003099728.1 CDS Amir_1934 NC_013093.1 2147431 2148255 D PFAM: UspA domain protein; KEGG: afw:Anae109_3830 universal stress family protein; UspA domain-containing protein 2147431..2148255 Actinosynnema mirum DSM 43827 8326119 YP_003099729.1 CDS Amir_1935 NC_013093.1 2148302 2148736 D PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 2148302..2148736 Actinosynnema mirum DSM 43827 8326120 YP_003099730.1 CDS Amir_1936 NC_013093.1 2148805 2149110 R hypothetical protein complement(2148805..2149110) Actinosynnema mirum DSM 43827 8326121 YP_003099731.1 CDS Amir_1937 NC_013093.1 2149252 2149857 R PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: xcv:XCV4086 LuxR family two-component response regulator; LuxR family transcriptional regulator complement(2149252..2149857) Actinosynnema mirum DSM 43827 8326122 YP_003099732.1 CDS Amir_1938 NC_013093.1 2149854 2150945 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: ccs:CCNA_01207 two-component sensor histidine kinase; histidine kinase complement(2149854..2150945) Actinosynnema mirum DSM 43827 8326123 YP_003099733.1 CDS Amir_1939 NC_013093.1 2150955 2151683 R PFAM: ABC transporter; KEGG: bca:BCE_5484 ABC transporter, permease protein; ABC transporter complement(2150955..2151683) Actinosynnema mirum DSM 43827 8326124 YP_003099734.1 CDS Amir_1940 NC_013093.1 2151683 2152603 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ccs:CCNA_01205 ABC transporter ATP-binding protein; ABC transporter complement(2151683..2152603) Actinosynnema mirum DSM 43827 8326125 YP_003099735.1 CDS Amir_1941 NC_013093.1 2152700 2153098 D KEGG: scl:sce6219 hypothetical protein; hypothetical protein 2152700..2153098 Actinosynnema mirum DSM 43827 8326126 YP_003099736.1 CDS Amir_1942 NC_013093.1 2153098 2153559 D hypothetical protein 2153098..2153559 Actinosynnema mirum DSM 43827 8326127 YP_003099737.1 CDS Amir_1943 NC_013093.1 2153564 2153731 R PFAM: protein of unknown function DUF397; hypothetical protein complement(2153564..2153731) Actinosynnema mirum DSM 43827 8326128 YP_003099738.1 CDS Amir_1944 NC_013093.1 2153728 2154567 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: cko:CKO_01491 hypothetical protein; XRE family transcriptional regulator complement(2153728..2154567) Actinosynnema mirum DSM 43827 8326129 YP_003099739.1 CDS Amir_1945 NC_013093.1 2154739 2155200 D KEGG: chromosome segregation protein SMC; K03529 chromosome segregation protein; chromosome segregation protein SMC; K03529 chromosome segregation protein 2154739..2155200 Actinosynnema mirum DSM 43827 8326130 YP_003099740.1 CDS Amir_1946 NC_013093.1 2155252 2156100 D KEGG: bpt:Bpet3209 spermidine synthase (putrescine aminopropyltransferase); spermidine synthase-like protein 2155252..2156100 Actinosynnema mirum DSM 43827 8326131 YP_003099741.1 CDS Amir_1947 NC_013093.1 2156270 2156977 R KEGG: hypothetical protein; hypothetical protein complement(2156270..2156977) Actinosynnema mirum DSM 43827 8326132 YP_003099742.1 CDS Amir_1948 NC_013093.1 2157127 2158161 R PFAM: ABC transporter; TOBE domain protein; SMART: ATPase AAA; KEGG: bac:BamMC406_1610 ABC transporter; ABC transporter complement(2157127..2158161) Actinosynnema mirum DSM 43827 8326133 YP_003099743.1 CDS Amir_1949 NC_013093.1 2158158 2158937 R TIGRFAM: molybdate ABC transporter, inner membrane subunit; NifC-like ABC-type porter; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce1134 ABC-type molybdate transporter, permease protein; molybdate ABC transporter, inner membrane subunit complement(2158158..2158937) Actinosynnema mirum DSM 43827 8326134 YP_003099744.1 CDS Amir_1950 NC_013093.1 2158934 2159728 R TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: scl:sce1135 ABC-type molybdate transporter, substrate-binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein complement(2158934..2159728) Actinosynnema mirum DSM 43827 8326135 YP_003099745.1 CDS Amir_1951 NC_013093.1 2159734 2160132 R TIGRFAM: DNA binding domain protein, excisionase family; PFAM: TOBE domain protein; regulatory protein MerR; KEGG: aba:Acid345_1548 molybdenum-pterin binding protein; excisionase family DNA binding domain-containing protein complement(2159734..2160132) Actinosynnema mirum DSM 43827 8326136 YP_003099746.1 CDS Amir_1952 NC_013093.1 2160337 2161062 R PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: pst:PSPTO_2646 TetR family transcriptional regulator; TetR family transcriptional regulator complement(2160337..2161062) Actinosynnema mirum DSM 43827 8326137 YP_003099747.1 CDS Amir_1953 NC_013093.1 2161152 2162630 D PFAM: major facilitator superfamily MFS_1; KEGG: smt:Smal_2153 major facilitator superfamily MFS_1; major facilitator superfamily protein 2161152..2162630 Actinosynnema mirum DSM 43827 8326138 YP_003099748.1 CDS Amir_1954 NC_013093.1 2162777 2164489 R TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: hypothetical protein; LPXTG-motif cell wall anchor domain-containing protein complement(2162777..2164489) Actinosynnema mirum DSM 43827 8326139 YP_003099749.1 CDS Amir_1955 NC_013093.1 2164726 2167434 D PFAM: Osmosensitive K channel His kinase sensor; ATP-binding region ATPase domain protein; UspA domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mrd:Mrad2831_0205 osmosensitive K+ channel signal transduction histidine kinase; Osmosensitive K channel His kinase sensor 2164726..2167434 Actinosynnema mirum DSM 43827 8326140 YP_003099750.1 CDS Amir_1956 NC_013093.1 2167526 2167864 D KEGG: hypothetical protein; hypothetical protein 2167526..2167864 Actinosynnema mirum DSM 43827 8326141 YP_003099751.1 CDS Amir_1957 NC_013093.1 2168094 2169128 R PFAM: PAS fold-3 domain protein; chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; PAC repeat- containing protein; KEGG: psp:PSPPH_4230 methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer complement(2168094..2169128) Actinosynnema mirum DSM 43827 8326142 YP_003099752.1 CDS Amir_1958 NC_013093.1 2169431 2169775 D KEGG: rso:RS05496 oxidoreductase protein; hypothetical protein 2169431..2169775 Actinosynnema mirum DSM 43827 8326143 YP_003099753.1 CDS Amir_1959 NC_013093.1 2169772 2170413 R PFAM: regulatory protein TetR; KEGG: acr:Acry_0512 TetR family transcriptional regulator; TetR family transcriptional regulator complement(2169772..2170413) Actinosynnema mirum DSM 43827 8326144 YP_003099754.1 CDS Amir_1960 NC_013093.1 2170502 2170702 R PFAM: protein of unknown function DUF1271; KEGG: bpy:Bphyt_4246 hypothetical protein; hypothetical protein complement(2170502..2170702) Actinosynnema mirum DSM 43827 8326145 YP_003099755.1 CDS Amir_1961 NC_013093.1 2170914 2172113 R PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 complement(2170914..2172113) Actinosynnema mirum DSM 43827 8326146 YP_003099756.1 CDS Amir_1962 NC_013093.1 2172443 2173321 D PFAM: Silent information regulator protein Sir2; KEGG: scl:sce3874 hypothetical protein; Silent information regulator protein Sir2 2172443..2173321 Actinosynnema mirum DSM 43827 8326147 YP_003099757.1 CDS Amir_1963 NC_013093.1 2173465 2173767 D hypothetical protein 2173465..2173767 Actinosynnema mirum DSM 43827 8326148 YP_003099758.1 CDS Amir_1964 NC_013093.1 2173760 2175085 D KEGG: mxa:MXAN_5876 hypothetical protein; hypothetical protein 2173760..2175085 Actinosynnema mirum DSM 43827 8326149 YP_003099759.1 CDS Amir_1965 NC_013093.1 2175082 2175981 D hypothetical protein 2175082..2175981 Actinosynnema mirum DSM 43827 8326150 YP_003099760.1 CDS Amir_1966 NC_013093.1 2176506 2176961 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bra:BRADO0101 organic hydroperoxide resistance transcriptional regulator; MarR family transcriptional regulator 2176506..2176961 Actinosynnema mirum DSM 43827 8326151 YP_003099761.1 CDS Amir_1967 NC_013093.1 2176958 2177356 D hypothetical protein 2176958..2177356 Actinosynnema mirum DSM 43827 8326152 YP_003099762.1 CDS Amir_1968 NC_013093.1 2177364 2178581 R PFAM: major facilitator superfamily MFS_1; KEGG: jan:Jann_0419 major facilitator transporter; major facilitator superfamily protein complement(2177364..2178581) Actinosynnema mirum DSM 43827 8326153 YP_003099763.1 CDS Amir_1969 NC_013093.1 2178843 2179700 R KEGG: pmy:Pmen_4204 hypothetical protein; triacylglycerol lipase complement(2178843..2179700) Actinosynnema mirum DSM 43827 8326154 YP_003099764.1 CDS Amir_1970 NC_013093.1 2180087 2182594 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: acp:A2cp1_3940 hypothetical protein; LuxR family transcriptional regulator 2180087..2182594 Actinosynnema mirum DSM 43827 8326155 YP_003099765.1 CDS Amir_1971 NC_013093.1 2183048 2184484 D PFAM: alpha-L-arabinofuranosidase B; glycosyl hydrolase family 32 domain protein; KEGG: scl:sce1247 hypothetical protein; alpha-L-arabinofuranosidase B 2183048..2184484 Actinosynnema mirum DSM 43827 8326156 YP_003099766.1 CDS Amir_1972 NC_013093.1 2184597 2185208 R PFAM: regulatory protein TetR; KEGG: aha:AHA_0553 TetR family transcriptional regulator; TetR family transcriptional regulator complement(2184597..2185208) Actinosynnema mirum DSM 43827 8326157 YP_003099767.1 CDS Amir_1973 NC_013093.1 2185208 2186122 R PFAM: saccharopine dehydrogenase; KEGG: bha:BH3388 hypothetical protein; saccharopine dehydrogenase complement(2185208..2186122) Actinosynnema mirum DSM 43827 8326158 YP_003099768.1 CDS Amir_1974 NC_013093.1 2186122 2186904 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: bja:bll4939 methyltransferase; type 11 methyltransferase complement(2186122..2186904) Actinosynnema mirum DSM 43827 8326159 YP_003099769.1 CDS Amir_1975 NC_013093.1 2187099 2189051 D PFAM: glycosyl hydrolase 67 middle domain protein; glycosyl hydrolase 67 C-teriminal domain protein; KEGG: bha:BH1061 alpha-glucuronidase; alpha-glucuronidase 2187099..2189051 Actinosynnema mirum DSM 43827 8326160 YP_003099770.1 CDS Amir_1976 NC_013093.1 2189301 2191340 R PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; beta-galactosidase domain protein; KEGG: bha:BH3701 beta-galactosidase; beta-galactosidase complement(2189301..2191340) Actinosynnema mirum DSM 43827 8326161 YP_003099771.1 CDS Amir_1977 NC_013093.1 2191337 2192023 R KEGG: afw:Anae109_4026 glycosyltransferase 36; glycosyl transferase family protein complement(2191337..2192023) Actinosynnema mirum DSM 43827 8326162 YP_003099772.1 CDS Amir_1978 NC_013093.1 2192020 2193558 R PFAM: glycoside hydrolase family 39; KEGG: bha:BH1068 beta-xylosidase; xylan 1,4-beta-xylosidase complement(2192020..2193558) Actinosynnema mirum DSM 43827 8326163 YP_003099773.1 CDS Amir_1979 NC_013093.1 2193564 2195192 R PFAM: extracellular solute-binding protein family 1; KEGG: atc:AGR_L_3560 AlgQ1, multiple sugar transport system substrate-binding protein; family 1 extracellular solute-binding protein complement(2193564..2195192) Actinosynnema mirum DSM 43827 8326164 YP_003099774.1 CDS Amir_1980 NC_013093.1 2195239 2196180 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bsu:BSU07120 transmembrane lipoprotein; ABC transporter inner membrane protein complement(2195239..2196180) Actinosynnema mirum DSM 43827 8326165 YP_003099775.1 CDS Amir_1981 NC_013093.1 2196177 2197175 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_3564 AlgM1, multiple sugar transport system permease protein; ABC transporter inner membrane protein complement(2196177..2197175) Actinosynnema mirum DSM 43827 8326166 YP_003099776.1 CDS Amir_1982 NC_013093.1 2197172 2199595 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: vei:Veis_0942 glycoside hydrolase, family 3 domain protein; glycoside hydrolase family protein complement(2197172..2199595) Actinosynnema mirum DSM 43827 8326167 YP_003099777.1 CDS Amir_1983 NC_013093.1 2199848 2200885 D KEGG: rpi:Rpic_0879 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 2199848..2200885 Actinosynnema mirum DSM 43827 8326168 YP_003099778.1 CDS Amir_1984 NC_013093.1 2201044 2202027 D PFAM: acetyl xylan esterase; KEGG: mlo:mlr6993 acetyl xylan esterase; acetyl xylan esterase 2201044..2202027 Actinosynnema mirum DSM 43827 8326169 YP_003099779.1 CDS Amir_1985 NC_013093.1 2202055 2202744 R PFAM: Clp domain protein; KEGG: ATP-dependent clp protease ATP-binding subunit; Clp domain-containing protein complement(2202055..2202744) Actinosynnema mirum DSM 43827 8326170 YP_003099780.1 CDS Amir_1986 NC_013093.1 2202807 2203169 R KEGG: ank:AnaeK_3385 hypothetical protein; hypothetical protein complement(2202807..2203169) Actinosynnema mirum DSM 43827 8326171 YP_003099781.1 CDS Amir_1987 NC_013093.1 2203266 2204171 D KEGG: scl:sce0848 protein kinase; hypothetical protein 2203266..2204171 Actinosynnema mirum DSM 43827 8326172 YP_003099782.1 CDS Amir_1988 NC_013093.1 2204210 2204755 R PFAM: regulatory protein TetR; KEGG: transcriptional regulator protein; TetR family transcriptional regulator complement(2204210..2204755) Actinosynnema mirum DSM 43827 8326173 YP_003099783.1 CDS Amir_1989 NC_013093.1 2205035 2205478 D hypothetical protein 2205035..2205478 Actinosynnema mirum DSM 43827 8326174 YP_003099784.1 CDS Amir_1990 NC_013093.1 2205495 2206226 D PFAM: aminoglycoside phosphotransferase; KEGG: sme:SMc02722 aminoglycoside 3'- phosphotransferase protein; aminoglycoside phosphotransferase 2205495..2206226 Actinosynnema mirum DSM 43827 8326175 YP_003099785.1 CDS Amir_1991 NC_013093.1 2206319 2206978 D PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hypothetical protein; Haloacid dehalogenase domain-containing protein hydrolase 2206319..2206978 Actinosynnema mirum DSM 43827 8326176 YP_003099786.1 CDS Amir_1992 NC_013093.1 2207022 2207612 R KEGG: hypothetical protein; hypothetical protein complement(2207022..2207612) Actinosynnema mirum DSM 43827 8326177 YP_003099787.1 CDS Amir_1993 NC_013093.1 2207609 2208022 R PFAM: protein of unknown function DUF1469; KEGG: gbm:Gbem_1384 protein of unknown function DUF1469; hypothetical protein complement(2207609..2208022) Actinosynnema mirum DSM 43827 8326178 YP_003099788.1 CDS Amir_1994 NC_013093.1 2208120 2209040 D TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN; KEGG: pfo:Pfl01_4350 ribonuclease BN; ribonuclease BN 2208120..2209040 Actinosynnema mirum DSM 43827 8326179 YP_003099789.1 CDS Amir_1995 NC_013093.1 2209081 2210115 R PFAM: alcohol dehydrogenase GroES domain protein; KEGG: scl:sce5062 hypothetical protein; alcohol dehydrogenase GroES domain-containing protein complement(2209081..2210115) Actinosynnema mirum DSM 43827 8326180 YP_003099790.1 CDS Amir_1996 NC_013093.1 2210124 2211428 R PFAM: aminotransferase class-III; KEGG: sat:SYN_01215 4-aminobutyrate aminotransferase; class III aminotransferase complement(2210124..2211428) Actinosynnema mirum DSM 43827 8326181 YP_003099791.1 CDS Amir_1997 NC_013093.1 2211428 2212984 R PFAM: glycosyl transferase family 20; KEGG: ank:AnaeK_0483 HAD-superfamily hydrolase, subfamily IIB; glycosyl transferase family protein complement(2211428..2212984) Actinosynnema mirum DSM 43827 8326182 YP_003099792.1 CDS Amir_1998 NC_013093.1 2213059 2213967 R PFAM: dTDP-4-dehydrorhamnose reductase; NAD- dependent epimerase/dehydratase; KEGG: acp:A2cp1_4446 dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase complement(2213059..2213967) Actinosynnema mirum DSM 43827 8326183 YP_003099793.1 CDS Amir_1999 NC_013093.1 2214258 2215532 R PFAM: major facilitator superfamily MFS_1; KEGG: major facilitator superfamily MFS_1 precursor; major facilitator superfamily protein complement(2214258..2215532) Actinosynnema mirum DSM 43827 8326184 YP_003099794.1 CDS Amir_2000 NC_013093.1 2215644 2216792 D PFAM: 3-dehydroquinate synthase; KEGG: reh:H16_A3434 3-dehydroquinate synthase; 3-dehydroquinate synthase 2215644..2216792 Actinosynnema mirum DSM 43827 8326185 YP_003099795.1 CDS Amir_2001 NC_013093.1 2216789 2218768 D PFAM: xylose isomerase; ATPase BadF/BadG/BcrA/BcrD type; KEGG: vei:Veis_3268 xylose isomerase domain protein TIM barrel; xylose isomerase 2216789..2218768 Actinosynnema mirum DSM 43827 8326186 YP_003099796.1 CDS Amir_2002 NC_013093.1 2218765 2219871 D PFAM: Nucleotidyl transferase; KEGG: cja:CJA_3254 glucose-1-phosphate adenylyltransferase; Nucleotidyl transferase 2218765..2219871 Actinosynnema mirum DSM 43827 8326187 YP_003099797.1 CDS Amir_2003 NC_013093.1 2219970 2220392 D PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3- methyltransferase; KEGG: lch:Lcho_1958 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2219970..2220392 Actinosynnema mirum DSM 43827 8326188 YP_003099798.1 CDS Amir_2004 NC_013093.1 2220429 2221010 R PFAM: regulatory protein TetR; KEGG: rle:RL2982 TetR family transcriptional regulator; TetR family transcriptional regulator complement(2220429..2221010) Actinosynnema mirum DSM 43827 8326189 YP_003099799.1 CDS Amir_2005 NC_013093.1 2221163 2222728 R KEGG: rce:RC1_2688 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase; malate synthase A complement(2221163..2222728) Actinosynnema mirum DSM 43827 8326190 YP_003099800.1 CDS Amir_2006 NC_013093.1 2222764 2224032 R TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sml:Smlt0232 isocitrate lyase; isocitrate lyase complement(2222764..2224032) Actinosynnema mirum DSM 43827 8326191 YP_003099801.1 CDS Amir_2007 NC_013093.1 2224237 2225652 D PFAM: protein of unknown function DUF955; helix- turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: rpt:Rpal_2644 transcriptional regulator, XRE family; XRE family transcriptional regulator 2224237..2225652 Actinosynnema mirum DSM 43827 8326192 YP_003099802.1 CDS Amir_2008 NC_013093.1 2225671 2226882 R KEGG: rec:RHECIAT_PC0000040 hypothetical protein; hypothetical protein complement(2225671..2226882) Actinosynnema mirum DSM 43827 8326193 YP_003099803.1 CDS Amir_2009 NC_013093.1 2227176 2228363 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 2227176..2228363 Actinosynnema mirum DSM 43827 8326194 YP_003099804.1 CDS Amir_2010 NC_013093.1 2228376 2229020 D PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 2228376..2229020 Actinosynnema mirum DSM 43827 8326195 YP_003099805.1 CDS Amir_2011 NC_013093.1 2229169 2230050 D KEGG: sfu:Sfum_3154 hypothetical protein; hypothetical protein 2229169..2230050 Actinosynnema mirum DSM 43827 8326196 YP_003099806.1 CDS Amir_2012 NC_013093.1 2230171 2231715 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 2230171..2231715 Actinosynnema mirum DSM 43827 8326197 YP_003099807.1 CDS Amir_2013 NC_013093.1 2232011 2233438 D PFAM: monooxygenase FAD-binding; KEGG: scl:sce4973 monooxygenase; FAD-binding monooxygenase 2232011..2233438 Actinosynnema mirum DSM 43827 8326198 YP_003099808.1 CDS Amir_2014 NC_013093.1 2233468 2233887 R hypothetical protein complement(2233468..2233887) Actinosynnema mirum DSM 43827 8326199 YP_003099809.1 CDS Amir_2015 NC_013093.1 2234529 2234954 R PFAM: sporulation and cell division protein SsgA; sporulation and cell division protein SsgA complement(2234529..2234954) Actinosynnema mirum DSM 43827 8326203 YP_003099810.1 CDS Amir_2016 NC_013093.1 2235175 2235852 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpi:Rpic_2575 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 2235175..2235852 Actinosynnema mirum DSM 43827 8326204 YP_003099811.1 CDS Amir_2017 NC_013093.1 2235849 2236652 D KEGG: GH10507 gene product from transcript GH10507- RA; hypothetical protein 2235849..2236652 Actinosynnema mirum DSM 43827 8326205 YP_003099812.1 CDS Amir_2018 NC_013093.1 2236667 2237086 D KEGG: swp:swp_2864 hypothetical protein swp_2864; hypothetical protein 2236667..2237086 Actinosynnema mirum DSM 43827 8326206 YP_003099813.1 CDS Amir_2020 NC_013093.1 2237988 2239670 R KEGG: bvi:Bcep1808_7197 integrase catalytic subunit; hypothetical protein complement(2237988..2239670) Actinosynnema mirum DSM 43827 8326209 YP_003099814.1 CDS Amir_2021 NC_013093.1 2240627 2241712 D KEGG: bid:Bind_1964 non-specific serine/threonine protein kinase; scyllo-inosamine-4-phosphate amidinotransferase 2240627..2241712 Actinosynnema mirum DSM 43827 8326210 YP_003099815.1 CDS Amir_2022 NC_013093.1 2241790 2243067 D catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 2241790..2243067 Actinosynnema mirum DSM 43827 8326211 YP_003099816.1 CDS Amir_2023 NC_013093.1 2243138 2243785 D KEGG: rec:RHECIAT_PB0000363 hypothetical protein; hypothetical protein 2243138..2243785 Actinosynnema mirum DSM 43827 8326212 YP_003099817.1 CDS Amir_2024 NC_013093.1 2243782 2244681 D PFAM: tryptophan 23-dioxygenase; KEGG: cak:Caul_5244 tryptophan 23-dioxygenase; tryptophan 23-dioxygenase 2243782..2244681 Actinosynnema mirum DSM 43827 8326213 YP_003099818.1 CDS Amir_2025 NC_013093.1 2244678 2245934 D PFAM: aminotransferase class V; KEGG: swi:Swit_0679 kynureninase; class V aminotransferase 2244678..2245934 Actinosynnema mirum DSM 43827 8326214 YP_003099819.1 CDS Amir_2026 NC_013093.1 2245939 2247210 D PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: bpd:BURPS668_0791 biotin carboxylase; ATP-dependent carboxylate-amine ligase domain-containing protein 2245939..2247210 Actinosynnema mirum DSM 43827 8326215 YP_003099820.1 CDS Amir_2027 NC_013093.1 2247241 2248551 D PFAM: major facilitator superfamily MFS_1; protein of unknown function DUF894 DitE; KEGG: rpc:RPC_4715 major facilitator transporter; major facilitator superfamily protein 2247241..2248551 Actinosynnema mirum DSM 43827 8326216 YP_003099821.1 CDS Amir_2028 NC_013093.1 2248548 2249507 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bmb:BruAb2_0285 amino acid ABC transporter, periplasmic amino acid-binding protein; family 3 extracellular solute-binding protein 2248548..2249507 Actinosynnema mirum DSM 43827 8326217 YP_003099822.1 CDS Amir_2029 NC_013093.1 2249565 2250950 D PFAM: amino acid permease-associated region; KEGG: bur:Bcep18194_C7638 amino acid transporter; amino acid permease-associated protein 2249565..2250950 Actinosynnema mirum DSM 43827 8326218 YP_003099823.1 CDS Amir_2030 NC_013093.1 2251035 2251259 D hypothetical protein 2251035..2251259 Actinosynnema mirum DSM 43827 8326219 YP_003099824.1 CDS Amir_2031 NC_013093.1 2251483 2252985 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce7656 carbohydrate ABC transporter; ABC transporter 2251483..2252985 Actinosynnema mirum DSM 43827 8326220 YP_003099825.1 CDS Amir_2032 NC_013093.1 2252985 2253323 D PFAM: peptidase S24 and S26 domain protein; KEGG: dal:Dalk_4340 signal peptidase I; peptidase S24 and S26 domain-containing protein 2252985..2253323 Actinosynnema mirum DSM 43827 8326221 YP_003099826.1 CDS Amir_2033 NC_013093.1 2253269 2253634 R SMART: helix-turn-helix domain protein; addiction module antidote protein complement(2253269..2253634) Actinosynnema mirum DSM 43827 8326222 YP_003099827.1 CDS Amir_2034 NC_013093.1 2253976 2254980 R PFAM: integral membrane protein TerC; KEGG: ade:Adeh_2303 integral membrane protein TerC; integral membrane protein TerC complement(2253976..2254980) Actinosynnema mirum DSM 43827 8326223 YP_003099828.1 CDS Amir_2036 NC_013093.1 2255481 2256647 R PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_0724 monooxygenase FAD-binding; FAD-binding monooxygenase complement(2255481..2256647) Actinosynnema mirum DSM 43827 8326225 YP_003099829.1 CDS Amir_2037 NC_013093.1 2256789 2257490 R KEGG: bcb:BCB4264_A2138 respiratory nitrate reductase, gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: nitrate reductase gamma subunit; respiratory nitrate reductase subunit gamma complement(2256789..2257490) Actinosynnema mirum DSM 43827 8326226 YP_003099830.1 CDS Amir_2038 NC_013093.1 2257487 2258110 R TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: nitrate reductase delta subunit; KEGG: bsu:BSU37260 nitrate reductase (protein J); nitrate reductase molybdenum cofactor assembly chaperone complement(2257487..2258110) Actinosynnema mirum DSM 43827 8326227 YP_003099831.1 CDS Amir_2039 NC_013093.1 2258107 2259642 R TIGRFAM: nitrate reductase, beta subunit; KEGG: bsu:BSU37270 nitrate reductase (beta subunit); nitrate reductase subunit beta complement(2258107..2259642) Actinosynnema mirum DSM 43827 8326228 YP_003099832.1 CDS Amir_2040 NC_013093.1 2259642 2263310 R KEGG: bcb:BCB4264_A2135 respiratory nitrate reductase, alpha subunit; TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; nitrate reductase subunit alpha complement(2259642..2263310) Actinosynnema mirum DSM 43827 8326229 YP_003099833.1 CDS Amir_2041 NC_013093.1 2263420 2264613 D PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_2929 major facilitator transporter; major facilitator superfamily protein 2263420..2264613 Actinosynnema mirum DSM 43827 8326230 YP_003099834.1 CDS Amir_2042 NC_013093.1 2264785 2265213 R KEGG: bcm:Bcenmc03_1697 hypothetical protein; hypothetical protein complement(2264785..2265213) Actinosynnema mirum DSM 43827 8326231 YP_003099835.1 CDS Amir_2043 NC_013093.1 2265267 2265959 R hypothetical protein complement(2265267..2265959) Actinosynnema mirum DSM 43827 8326232 YP_003099836.1 CDS Amir_2044 NC_013093.1 2266002 2266223 R hypothetical protein complement(2266002..2266223) Actinosynnema mirum DSM 43827 8326233 YP_003099837.1 CDS Amir_2045 NC_013093.1 2266370 2266543 D hypothetical protein 2266370..2266543 Actinosynnema mirum DSM 43827 8326234 YP_003099838.1 CDS Amir_2046 NC_013093.1 2266727 2268172 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 2266727..2268172 Actinosynnema mirum DSM 43827 8326235 YP_003099839.1 CDS Amir_2047 NC_013093.1 2268249 2270828 R PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; KEGG: hypothetical protein; alpha-L-rhamnosidase complement(2268249..2270828) Actinosynnema mirum DSM 43827 8326236 YP_003099840.1 CDS Amir_2048 NC_013093.1 2271015 2273054 R PFAM: cellulose-binding family II; Fibronectin type III domain protein; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: cak:Caul_2415 alpha-N-arabinofuranosidase; cellulose-binding family protein complement(2271015..2273054) Actinosynnema mirum DSM 43827 8326237 YP_003099841.1 CDS Amir_2049 NC_013093.1 2273320 2274330 R PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: pst:PSPTO_4577 glycine betaine/choline OpuC ABC transporter, periplasmic substrate-binding protein; glycine/betaine ABC transporter substrate-binding protein complement(2273320..2274330) Actinosynnema mirum DSM 43827 8326238 YP_003099842.1 CDS Amir_2050 NC_013093.1 2274327 2275103 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bsu:BSU33720 choline ABC transporter membrane protein; ABC transporter inner membrane protein complement(2274327..2275103) Actinosynnema mirum DSM 43827 8326239 YP_003099843.1 CDS Amir_2051 NC_013093.1 2275100 2276212 R KEGG: pol:Bpro_1154 glycine betaine/L-proline transport ATP binding subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; glycine betaine/L-proline ABC transporter ATPase subunit complement(2275100..2276212) Actinosynnema mirum DSM 43827 8326240 YP_003099844.1 CDS Amir_2052 NC_013093.1 2276202 2276852 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1467 inner-membrane permease; ABC transporter inner membrane protein complement(2276202..2276852) Actinosynnema mirum DSM 43827 8326241 YP_003099845.1 CDS Amir_2053 NC_013093.1 2277242 2277880 R KEGG: gsu:GSU0139 hypothetical protein; hypothetical protein complement(2277242..2277880) Actinosynnema mirum DSM 43827 8326242 YP_003099846.1 CDS Amir_2054 NC_013093.1 2278287 2279423 D KEGG: acr:Acry_0984 extracellular solute-binding protein; extracellular solute-binding protein 2278287..2279423 Actinosynnema mirum DSM 43827 8326243 YP_003099847.1 CDS Amir_2055 NC_013093.1 2279427 2280338 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: acr:Acry_0983 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2279427..2280338 Actinosynnema mirum DSM 43827 8326244 YP_003099848.1 CDS Amir_2056 NC_013093.1 2280329 2281144 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_1679 ABC transporter permease; ABC transporter inner membrane protein 2280329..2281144 Actinosynnema mirum DSM 43827 8326245 YP_003099849.1 CDS Amir_2057 NC_013093.1 2281146 2282231 D PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: acr:Acry_0981 ABC transporter; ABC transporter 2281146..2282231 Actinosynnema mirum DSM 43827 8326246 YP_003099850.1 CDS Amir_2058 NC_013093.1 2282315 2283757 R KEGG: sus:Acid_3131 secreted protein; hypothetical protein complement(2282315..2283757) Actinosynnema mirum DSM 43827 8326247 YP_003099851.1 CDS Amir_2059 NC_013093.1 2283961 2284587 D PFAM: protein of unknown function DUF305; KEGG: eli:ELI_14360 secreted protein; hypothetical protein 2283961..2284587 Actinosynnema mirum DSM 43827 8326248 YP_003099852.1 CDS Amir_2060 NC_013093.1 2284777 2285037 R hypothetical protein complement(2284777..2285037) Actinosynnema mirum DSM 43827 8326249 YP_003099853.1 CDS Amir_2061 NC_013093.1 2285251 2285727 R PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sus:Acid_2535 guanine deaminase; zinc-binding CMP/dCMP deaminase complement(2285251..2285727) Actinosynnema mirum DSM 43827 8326250 YP_003099854.1 CDS Amir_2062 NC_013093.1 2285820 2286116 R TIGRFAM: hydroxyisourate hydrolase; PFAM: transthyretin; KEGG: hypothetical protein; hydroxyisourate hydrolase complement(2285820..2286116) Actinosynnema mirum DSM 43827 8326251 YP_003099855.1 CDS Amir_2063 NC_013093.1 2286271 2287956 D PFAM: purine catabolism PurC domain protein; KEGG: GK24882 gene product from transcript GK24882- RA; PucR family transcriptional regulator 2286271..2287956 Actinosynnema mirum DSM 43827 8326252 YP_003099856.1 CDS Amir_2064 NC_013093.1 2288071 2289039 D KEGG: aav:Aave_4523 superoxide dismutase; superoxide dismutase 2288071..2289039 Actinosynnema mirum DSM 43827 8326253 YP_003099857.1 CDS Amir_2065 NC_013093.1 2289064 2289165 D hypothetical protein 2289064..2289165 Actinosynnema mirum DSM 43827 8326254 YP_003099858.1 CDS Amir_2066 NC_013093.1 2289272 2291728 D PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: lch:Lcho_0275 histidine kinase; ATP-binding region ATPase domain-containing protein 2289272..2291728 Actinosynnema mirum DSM 43827 8326255 YP_003099859.1 CDS Amir_2067 NC_013093.1 2291773 2292201 D PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_2813 roadblock/LC7 family protein; Roadblock/LC7 family protein 2291773..2292201 Actinosynnema mirum DSM 43827 8326256 YP_003099860.1 CDS Amir_2068 NC_013093.1 2292198 2292566 D PFAM: protein of unknown function DUF742; hypothetical protein 2292198..2292566 Actinosynnema mirum DSM 43827 8326257 YP_003099861.1 CDS Amir_2069 NC_013093.1 2292547 2293140 D PFAM: protein of unknown function ATP binding; KEGG: dac:Daci_0776 protein of unknown function ATP binding; hypothetical protein 2292547..2293140 Actinosynnema mirum DSM 43827 8326258 YP_003099862.1 CDS Amir_2070 NC_013093.1 2293141 2294439 R PFAM: flavin-containing monooxygenase FMO; FAD- dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pla:Plav_0443 flavin-containing monooxygenase; flavin-containing monooxygenase complement(2293141..2294439) Actinosynnema mirum DSM 43827 8326259 YP_003099863.1 CDS Amir_2071 NC_013093.1 2294631 2295752 D KEGG: met:M446_0097 hypothetical protein; hypothetical protein 2294631..2295752 Actinosynnema mirum DSM 43827 8326260 YP_003099864.1 CDS Amir_2072 NC_013093.1 2295899 2296483 D PFAM: protein of unknown function UPF0157; KEGG: mxa:MXAN_5238 hypothetical protein; hypothetical protein 2295899..2296483 Actinosynnema mirum DSM 43827 8326261 YP_003099865.1 CDS Amir_2073 NC_013093.1 2296533 2297393 R PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: gbm:Gbem_1461 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxybutyryl-CoA dehydrogenase complement(2296533..2297393) Actinosynnema mirum DSM 43827 8326262 YP_003099866.1 CDS Amir_2074 NC_013093.1 2297519 2298187 R PFAM: SCP-like extracellular; KEGG: noc:Noc_1373 hypothetical protein; SCP-like extracellular complement(2297519..2298187) Actinosynnema mirum DSM 43827 8326263 YP_003099867.1 CDS Amir_2075 NC_013093.1 2298286 2299701 R TIGRFAM: ethanolamine transproter; PFAM: amino acid permease-associated region; KEGG: ppg:PputGB1_0589 ethanolamine transproter; ethanolamine transporter complement(2298286..2299701) Actinosynnema mirum DSM 43827 8326264 YP_003099868.1 CDS Amir_2076 NC_013093.1 2299823 2301187 D PFAM: glutamine synthetase catalytic region; KEGG: acr:Acry_2393 glutamine synthetase, catalytic region; glutamate--ammonia ligase 2299823..2301187 Actinosynnema mirum DSM 43827 8326265 YP_003099869.1 CDS Amir_2077 NC_013093.1 2301168 2301869 D PFAM: peptidase C26; glutamine amidotransferase class-I; KEGG: rru:Rru_A0651 glutamine amidotransferase class-I; peptidase C26 2301168..2301869 Actinosynnema mirum DSM 43827 8326266 YP_003099870.1 CDS Amir_2078 NC_013093.1 2301866 2303224 D PFAM: Aldehyde Dehydrogenase; KEGG: swi:Swit_1745 aldehyde dehydrogenase (acceptor); aldehyde dehydrogenase 2301866..2303224 Actinosynnema mirum DSM 43827 8326267 YP_003099871.1 CDS Amir_2079 NC_013093.1 2303283 2304050 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: hypothetical protein; short chain dehydrogenase 2303283..2304050 Actinosynnema mirum DSM 43827 8326268 YP_003099872.1 CDS Amir_2080 NC_013093.1 2304064 2304765 D PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; Helix-turn-helix type 11 domain protein; SMART: regulatory protein GntR HTH; KEGG: swi:Swit_1674 GntR family transcriptional regulator; GntR family transcriptional regulator 2304064..2304765 Actinosynnema mirum DSM 43827 8326269 YP_003099873.1 CDS Amir_2081 NC_013093.1 2304836 2305597 D KEGG: bav:BAV1541 competence protein; hypothetical protein 2304836..2305597 Actinosynnema mirum DSM 43827 8326270 YP_003099874.1 CDS Amir_2082 NC_013093.1 2305594 2306076 D hypothetical protein 2305594..2306076 Actinosynnema mirum DSM 43827 8326271 YP_003099875.1 CDS Amir_2083 NC_013093.1 2306154 2306657 D KEGG: ank:AnaeK_2798 response regulator receiver; response regulator receiver 2306154..2306657 Actinosynnema mirum DSM 43827 8326272 YP_003099876.1 CDS Amir_2084 NC_013093.1 2306785 2307630 D KEGG: saz:Sama_0820 lipoprotein; hypothetical protein 2306785..2307630 Actinosynnema mirum DSM 43827 8326273 YP_003099877.1 CDS Amir_2085 NC_013093.1 2307658 2308614 D KEGG: acp:A2cp1_4055 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; daunorubicin ABC transporter ATPase 2307658..2308614 Actinosynnema mirum DSM 43827 8326274 YP_003099878.1 CDS Amir_2086 NC_013093.1 2308611 2309414 D PFAM: ABC transporter; KEGG: bcz:BCZK3149 ABC transporter efflux permease; daunorubicin resistance transmembrane protein; daunorubicin ABC transporter transmembrane protein 2308611..2309414 Actinosynnema mirum DSM 43827 8326275 YP_003099879.1 CDS Amir_2087 NC_013093.1 2309460 2309666 R hypothetical protein complement(2309460..2309666) Actinosynnema mirum DSM 43827 8326276 YP_003099880.1 CDS thrS NC_013093.1 2310424 2312472 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2310424..2312472 Actinosynnema mirum DSM 43827 8326278 YP_003099881.1 CDS Amir_2090 NC_013093.1 2312469 2313017 D PFAM: histidine triad (HIT) protein; KEGG: pca:Pcar_1504 HIT (HINT, histidine triad) family protein; histidine triad (HIT) protein 2312469..2313017 Actinosynnema mirum DSM 43827 8326279 YP_003099882.1 CDS Amir_2091 NC_013093.1 2313814 2314575 D hypothetical protein 2313814..2314575 Actinosynnema mirum DSM 43827 8326280 YP_003099883.1 CDS Amir_2092 NC_013093.1 2314637 2315284 D PFAM: CDP-alcohol phosphatidyltransferase; KEGG: noc:Noc_2982 CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase 2314637..2315284 Actinosynnema mirum DSM 43827 8326281 YP_003099884.1 CDS Amir_2093 NC_013093.1 2315281 2316213 D acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 2315281..2316213 Actinosynnema mirum DSM 43827 8326282 YP_003099885.1 CDS Amir_2094 NC_013093.1 2316210 2317337 D PFAM: glycosyl transferase group 1; KEGG: acp:A2cp1_4300 phosphatidylinositol alpha- mannosyltransferase; phosphatidylinositol alpha-mannosyltransferase 2316210..2317337 Actinosynnema mirum DSM 43827 8326283 YP_003099886.1 CDS Amir_2095 NC_013093.1 2317334 2318317 D PFAM: NUDIX hydrolase; KEGG: pzu:PHZ_c0948 mutator MutT protein; NUDIX hydrolase 2317334..2318317 Actinosynnema mirum DSM 43827 8326284 YP_003099887.1 CDS Amir_2096 NC_013093.1 2318395 2318772 R PFAM: protein of unknown function DUF1696; KEGG: vpa:VPA1559 hypothetical protein; hypothetical protein complement(2318395..2318772) Actinosynnema mirum DSM 43827 8326285 YP_003099888.1 CDS Amir_2097 NC_013093.1 2318920 2319465 R hypothetical protein complement(2318920..2319465) Actinosynnema mirum DSM 43827 8326286 YP_003099889.1 CDS Amir_2098 NC_013093.1 2319462 2320454 R PFAM: luciferase-like monooxygenase; KEGG: pde:Pden_1120 luciferase family protein; luciferase-like monooxygenase complement(2319462..2320454) Actinosynnema mirum DSM 43827 8326287 YP_003099890.1 CDS Amir_2099 NC_013093.1 2320465 2321856 R catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase complement(2320465..2321856) Actinosynnema mirum DSM 43827 8326288 YP_003099891.1 CDS Amir_2100 NC_013093.1 2321853 2322695 R PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sus:Acid_7663 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase complement(2321853..2322695) Actinosynnema mirum DSM 43827 8326289 YP_003099892.1 CDS Amir_2101 NC_013093.1 2322692 2324194 R TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sus:Acid_7658 NCS1 nucleoside transporter; NCS1 nucleoside transporter family complement(2322692..2324194) Actinosynnema mirum DSM 43827 8326290 YP_003099893.1 CDS Amir_2102 NC_013093.1 2324545 2324808 D hypothetical protein 2324545..2324808 Actinosynnema mirum DSM 43827 8326291 YP_003099894.1 CDS Amir_2103 NC_013093.1 2324805 2326415 R PFAM: purine catabolism PurC domain protein; KEGG: pag:PLES_34081 regulatory protein; PucR family transcriptional regulator complement(2324805..2326415) Actinosynnema mirum DSM 43827 8326292 YP_003099895.1 CDS Amir_2104 NC_013093.1 2326533 2327825 D PFAM: aminotransferase class-III; KEGG: sus:Acid_7662 aminotransferase; class III aminotransferase 2326533..2327825 Actinosynnema mirum DSM 43827 8326293 YP_003099896.1 CDS Amir_2105 NC_013093.1 2327822 2329363 D TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: sus:Acid_0680 methylmalonate-semialdehyde dehydrogenase [acylating]; methylmalonate-semialdehyde dehydrogenase 2327822..2329363 Actinosynnema mirum DSM 43827 8326294 YP_003099897.1 CDS Amir_2106 NC_013093.1 2329561 2329875 D hypothetical protein 2329561..2329875 Actinosynnema mirum DSM 43827 8326295 YP_003099898.1 CDS Amir_2107 NC_013093.1 2330391 2332616 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(2330391..2332616) Actinosynnema mirum DSM 43827 8326296 YP_003099899.1 CDS Amir_2108 NC_013093.1 2332890 2333858 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 2332890..2333858 Actinosynnema mirum DSM 43827 8326297 YP_003099900.1 CDS Amir_2109 NC_013093.1 2334894 2335508 D PFAM: SNO glutamine amidotransferase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: dds:Ddes_1897 SNO glutamine amidotransferase; SNO glutamine amidotransferase 2334894..2335508 Actinosynnema mirum DSM 43827 8326298 YP_003099901.1 CDS Amir_2110 NC_013093.1 2335528 2336283 D PFAM: protein of unknown function DUF28; KEGG: gme:Gmet_0743 hypothetical protein; hypothetical protein 2335528..2336283 Actinosynnema mirum DSM 43827 8326299 YP_003099902.1 CDS Amir_2111 NC_013093.1 2336341 2336868 D KEGG: pna:Pnap_0373 hypothetical protein; hypothetical protein 2336341..2336868 Actinosynnema mirum DSM 43827 8326300 YP_003099903.1 CDS Amir_2112 NC_013093.1 2337013 2337546 R hypothetical protein complement(2337013..2337546) Actinosynnema mirum DSM 43827 8326301 YP_003099904.1 CDS Amir_2113 NC_013093.1 2337641 2338189 R PFAM: regulatory protein TetR; KEGG: smt:Smal_2152 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(2337641..2338189) Actinosynnema mirum DSM 43827 8326302 YP_003099905.1 CDS Amir_2114 NC_013093.1 2338211 2339716 R PFAM: major facilitator superfamily MFS_1; KEGG: smt:Smal_2153 major facilitator superfamily MFS_1; major facilitator superfamily protein complement(2338211..2339716) Actinosynnema mirum DSM 43827 8326303 YP_003099906.1 CDS Amir_2115 NC_013093.1 2339992 2341284 R PFAM: cytochrome P450; KEGG: mrd:Mrad2831_3880 cytochrome P450; cytochrome P450 complement(2339992..2341284) Actinosynnema mirum DSM 43827 8326304 YP_003099907.1 CDS Amir_2116 NC_013093.1 2341316 2342485 R PFAM: cytochrome P450; KEGG: pag:PLES_17331 cytochrome P450; cytochrome P450 complement(2341316..2342485) Actinosynnema mirum DSM 43827 8326305 YP_003099908.1 CDS Amir_2117 NC_013093.1 2342700 2343788 D PFAM: regulatory protein TetR; KEGG: sus:Acid_6248 TetR family transcriptional regulator; TetR family transcriptional regulator 2342700..2343788 Actinosynnema mirum DSM 43827 8326306 YP_003099909.1 CDS Amir_2118 NC_013093.1 2344146 2344607 R PFAM: thioesterase superfamily protein; KEGG: mxa:MXAN_4456 thioesterase family protein; thioesterase superfamily protein complement(2344146..2344607) Actinosynnema mirum DSM 43827 8326307 YP_003099910.1 CDS Amir_2119 NC_013093.1 2344618 2345778 R PFAM: major facilitator superfamily MFS_1; KEGG: nmu:Nmul_A1807 hypothetical protein; major facilitator superfamily protein complement(2344618..2345778) Actinosynnema mirum DSM 43827 8326308 YP_003099911.1 CDS Amir_2120 NC_013093.1 2345948 2346544 R PFAM: regulatory protein TetR; KEGG: azo:azo0243 TetR family transcriptional regulator; TetR family transcriptional regulator complement(2345948..2346544) Actinosynnema mirum DSM 43827 8326309 YP_003099912.1 CDS Amir_2121 NC_013093.1 2346699 2347658 D KEGG: hypothetical protein LOC761802; hypothetical protein 2346699..2347658 Actinosynnema mirum DSM 43827 8326310 YP_003099913.1 CDS Amir_2122 NC_013093.1 2347740 2348966 D PFAM: glutamate--cysteine ligase GCS2; KEGG: acp:A2cp1_3936 glutamate--cysteine ligase; glutamate--cysteine ligase GCS2 2347740..2348966 Actinosynnema mirum DSM 43827 8326311 YP_003099914.1 CDS Amir_2123 NC_013093.1 2349328 2350656 D PFAM: protein of unknown function DUF323; KEGG: mxa:MXAN_7471 hypothetical protein; hypothetical protein 2349328..2350656 Actinosynnema mirum DSM 43827 8326312 YP_003099915.1 CDS Amir_2124 NC_013093.1 2350657 2351415 D KEGG: mch:Mchl_5354 glutamine amidotransferase class-II; glutamine amidotransferase 2350657..2351415 Actinosynnema mirum DSM 43827 8326313 YP_003099916.1 CDS Amir_2125 NC_013093.1 2351412 2352374 D TIGRFAM: methyltransferase; KEGG: mxa:MXAN_7473 hypothetical protein; methyltransferase 2351412..2352374 Actinosynnema mirum DSM 43827 8326314 YP_003099917.1 CDS Amir_2126 NC_013093.1 2352448 2352675 R hypothetical protein complement(2352448..2352675) Actinosynnema mirum DSM 43827 8326315 YP_003099918.1 CDS Amir_2127 NC_013093.1 2352944 2353807 D SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein 2352944..2353807 Actinosynnema mirum DSM 43827 8326316 YP_003099919.1 CDS Amir_2128 NC_013093.1 2353820 2354014 D PFAM: protein of unknown function DUF397; hypothetical protein 2353820..2354014 Actinosynnema mirum DSM 43827 8326317 YP_003099920.1 CDS Amir_2129 NC_013093.1 2354410 2354622 R hypothetical protein complement(2354410..2354622) Actinosynnema mirum DSM 43827 8326318 YP_003099921.1 CDS Amir_2130 NC_013093.1 2354869 2355252 D PFAM: peptidoglycan-binding domain 1 protein; peptidoglycan-binding domain 1 protein 2354869..2355252 Actinosynnema mirum DSM 43827 8326319 YP_003099922.1 CDS Amir_2131 NC_013093.1 2355321 2355695 D PFAM: peptidoglycan-binding domain 1 protein; KEGG: mes:Meso_0085 peptidoglycan-binding domain 1; peptidoglycan-binding domain 1 protein 2355321..2355695 Actinosynnema mirum DSM 43827 8326320 YP_003099923.1 CDS Amir_2132 NC_013093.1 2355760 2358585 R TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: eba:ebA6773 aconitate hydratase; aconitate hydratase 1 complement(2355760..2358585) Actinosynnema mirum DSM 43827 8326321 YP_003099924.1 CDS Amir_2133 NC_013093.1 2358831 2359667 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bat:BAS4648 ABC transporter, ATP-binding protein; ABC transporter 2358831..2359667 Actinosynnema mirum DSM 43827 8326322 YP_003099925.1 CDS Amir_2134 NC_013093.1 2359664 2360314 D KEGG: bce:BC4749 ABC transporter permease protein; hypothetical protein 2359664..2360314 Actinosynnema mirum DSM 43827 8326323 YP_003099926.1 CDS Amir_2135 NC_013093.1 2360379 2360837 D KEGG: ade:Adeh_3822 AraC family transcriptional regulator; AraC family transcriptional regulator 2360379..2360837 Actinosynnema mirum DSM 43827 8326324 YP_003099927.1 CDS Amir_2136 NC_013093.1 2360848 2362002 R KEGG: bch:Bcen2424_6766 PE-PGRS family protein; hypothetical protein complement(2360848..2362002) Actinosynnema mirum DSM 43827 8326325 YP_003099928.1 CDS Amir_2137 NC_013093.1 2362104 2362868 D PFAM: Silent information regulator protein Sir2; KEGG: sat:SYN_00042 sir2 family protein; Silent information regulator protein Sir2 2362104..2362868 Actinosynnema mirum DSM 43827 8326326 YP_003099929.1 CDS Amir_2138 NC_013093.1 2362949 2363524 D PFAM: carbonic anhydrase; KEGG: xau:Xaut_2228 carbonate dehydratase; carbonic anhydrase 2362949..2363524 Actinosynnema mirum DSM 43827 8326327 YP_003099930.1 CDS Amir_2139 NC_013093.1 2363636 2365168 D PFAM: AMP-dependent synthetase and ligase; KEGG: sus:Acid_7357 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 2363636..2365168 Actinosynnema mirum DSM 43827 8326328 YP_003099931.1 CDS Amir_2140 NC_013093.1 2365302 2366585 D PFAM: NLP/P60 protein; KEGG: NlpC/P60-like cell-wall peptidase; NLP/P60 protein 2365302..2366585 Actinosynnema mirum DSM 43827 8326329 YP_003099932.1 CDS Amir_2141 NC_013093.1 2366708 2367310 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: mmr:Mmar10_0581 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 2366708..2367310 Actinosynnema mirum DSM 43827 8326330 YP_003099933.1 CDS Amir_2142 NC_013093.1 2367373 2367750 D KEGG: rle:RL0353 transmembrane transport protein; transmembrane transport protein 2367373..2367750 Actinosynnema mirum DSM 43827 8326331 YP_003099934.1 CDS Amir_2143 NC_013093.1 2368599 2369147 R KEGG: pfl:PFL_3722 molybdopterin-guanine dinucleotide biosynthesis protein A; molybdopterin-guanine dinucleotide biosynthesis protein A complement(2368599..2369147) Actinosynnema mirum DSM 43827 8326332 YP_003099935.1 CDS Amir_2144 NC_013093.1 2369297 2369941 R PFAM: thiopurine S-methyltransferase; KEGG: psa:PST_2541 thiopurine S-methyltransferase; Thiopurine S-methyltransferase complement(2369297..2369941) Actinosynnema mirum DSM 43827 8326333 YP_003099936.1 CDS Amir_2145 NC_013093.1 2370097 2371137 D PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: reh:H16_B1613 MoxR-like ATPase; ATPase 2370097..2371137 Actinosynnema mirum DSM 43827 8326334 YP_003099937.1 CDS Amir_2146 NC_013093.1 2371185 2372189 D PFAM: protein of unknown function DUF58; KEGG: pna:Pnap_3246 protein of unknown function DUF58; hypothetical protein 2371185..2372189 Actinosynnema mirum DSM 43827 8326335 YP_003099938.1 CDS Amir_2147 NC_013093.1 2372189 2373154 D PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: azo:azo2864 hypothetical protein; hypothetical protein 2372189..2373154 Actinosynnema mirum DSM 43827 8326336 YP_003099939.1 CDS Amir_2148 NC_013093.1 2373151 2373723 D KEGG: swp:swp_0140 hypothetical protein; hypothetical protein 2373151..2373723 Actinosynnema mirum DSM 43827 8326337 YP_003099940.1 CDS Amir_2149 NC_013093.1 2373734 2374621 R TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: psa:PST_4124 periplasmic binding protein; TRAP transporter solute receptor, TAXI family complement(2373734..2374621) Actinosynnema mirum DSM 43827 8326338 YP_003099941.1 CDS Amir_2150 NC_013093.1 2374618 2375988 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: scl:sce7107 sensor histidine kinase; histidine kinase complement(2374618..2375988) Actinosynnema mirum DSM 43827 8326339 YP_003099942.1 CDS Amir_2151 NC_013093.1 2375993 2376646 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: afw:Anae109_0880 two component transcriptional regulator; winged helix family two component transcriptional regulator complement(2375993..2376646) Actinosynnema mirum DSM 43827 8326340 YP_003099943.1 CDS Amir_2152 NC_013093.1 2376701 2377435 D PFAM: ANTAR domain protein; GAF domain protein; SMART: GAF domain protein; KEGG: sus:Acid_4463 GAF sensor protein; ANTAR domain-containing protein with unknown sensor 2376701..2377435 Actinosynnema mirum DSM 43827 8326341 YP_003099944.1 CDS Amir_2153 NC_013093.1 2377876 2378334 D KEGG: dvm:DvMF_1072 hypothetical protein; hypothetical protein 2377876..2378334 Actinosynnema mirum DSM 43827 8326342 YP_003099945.1 CDS Amir_2154 NC_013093.1 2378381 2379298 R TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: maq:Maqu_2160 hypothetical protein; LPXTG-motif cell wall anchor domain-containing protein complement(2378381..2379298) Actinosynnema mirum DSM 43827 8326343 YP_003099946.1 CDS Amir_2155 NC_013093.1 2379375 2380637 R KEGG: maq:Maqu_2160 hypothetical protein; hypothetical protein complement(2379375..2380637) Actinosynnema mirum DSM 43827 8326344 YP_003099947.1 CDS Amir_2156 NC_013093.1 2380880 2381521 D KEGG: maq:Maqu_2160 hypothetical protein; hypothetical protein 2380880..2381521 Actinosynnema mirum DSM 43827 8326345 YP_003099948.1 CDS Amir_2157 NC_013093.1 2381678 2382757 D TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: bph:Bphy_2768 hypothetical protein; virulence factor Mce family protein 2381678..2382757 Actinosynnema mirum DSM 43827 8326346 YP_003099949.1 CDS Amir_2158 NC_013093.1 2382757 2383785 D TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sfu:Sfum_0474 mammalian cell entry related domain protein; virulence factor Mce family protein 2382757..2383785 Actinosynnema mirum DSM 43827 8326347 YP_003099950.1 CDS Amir_2159 NC_013093.1 2383782 2384747 D TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: gme:Gmet_1272 virulence factor MCE-like protein-related protein; virulence factor Mce family protein 2383782..2384747 Actinosynnema mirum DSM 43827 8326348 YP_003099951.1 CDS Amir_2160 NC_013093.1 2384747 2385751 D TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sat:SYN_00409 ABC-type transport system involved in resistance to organic solvents, periplasmic component; virulence factor Mce family protein 2384747..2385751 Actinosynnema mirum DSM 43827 8326349 YP_003099952.1 CDS Amir_2161 NC_013093.1 2385748 2386737 D TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sat:SYN_00409 ABC-type transport system involved in resistance to organic solvents, periplasmic component; virulence factor Mce family protein 2385748..2386737 Actinosynnema mirum DSM 43827 8326350 YP_003099953.1 CDS Amir_2162 NC_013093.1 2386743 2387789 D TIGRFAM: virulence factor Mce family protein; PFAM: Mammalian cell entry related domain protein; KEGG: sat:SYN_00409 ABC-type transport system involved in resistance to organic solvents, periplasmic component; virulence factor Mce family protein 2386743..2387789 Actinosynnema mirum DSM 43827 8326351 YP_003099954.1 CDS Amir_2163 NC_013093.1 2387893 2388432 D hypothetical protein 2387893..2388432 Actinosynnema mirum DSM 43827 8326352 YP_003099955.1 CDS Amir_2164 NC_013093.1 2388640 2389527 D PFAM: aminoglycoside phosphotransferase; KEGG: bra:BRADO6829 phosphotransferase; aminoglycoside phosphotransferase 2388640..2389527 Actinosynnema mirum DSM 43827 8326353 YP_003099956.1 CDS Amir_2165 NC_013093.1 2389532 2389900 R KEGG: tgr:Tgr7_1062 sec-C motif domain protein; sec-C motif domain-containing protein complement(2389532..2389900) Actinosynnema mirum DSM 43827 8326354 YP_003099957.1 CDS Amir_2166 NC_013093.1 2389972 2391369 R KEGG: mxa:MXAN_4837 endoglucanase; PFAM: glycoside hydrolase family 6; cellulose- binding family II; SMART: cellulose-binding family II; Cellulase complement(2389972..2391369) Actinosynnema mirum DSM 43827 8326355 YP_003099958.1 CDS Amir_2167 NC_013093.1 2392660 2395584 D PFAM: glycoside hydrolase family 48; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: hch:HCH_02465 RTX toxins and related Ca2+- binding protein; glycoside hydrolase family protein 2392660..2395584 Actinosynnema mirum DSM 43827 8326356 YP_003099959.1 CDS Amir_2168 NC_013093.1 2395750 2398377 D PFAM: glycoside hydrolase family 3 domain protein; KEGG: bha:BH1908 glucan 1,4-beta-glucosidase; beta-glucosidase 2395750..2398377 Actinosynnema mirum DSM 43827 8326357 YP_003099960.1 CDS Amir_2169 NC_013093.1 2398377 2399390 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bam:Bamb_4929 LacI family transcription regulator; LacI family transcriptional regulator 2398377..2399390 Actinosynnema mirum DSM 43827 8326358 YP_003099961.1 CDS Amir_2170 NC_013093.1 2399697 2401295 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH0482 lipoprotein; family 1 extracellular solute-binding protein 2399697..2401295 Actinosynnema mirum DSM 43827 8326359 YP_003099962.1 CDS Amir_2171 NC_013093.1 2401282 2402256 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bha:BH0484 transmembrane lipoprotein; ABC transporter inner membrane protein 2401282..2402256 Actinosynnema mirum DSM 43827 8326360 YP_003099963.1 CDS Amir_2172 NC_013093.1 2402253 2403218 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bsu:BSU30170 hypothetical protein; ABC transporter inner membrane protein 2402253..2403218 Actinosynnema mirum DSM 43827 8326361 YP_003099964.1 CDS Amir_2173 NC_013093.1 2403256 2405238 D PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; beta-galactosidase domain protein; KEGG: bha:BH3701 beta-galactosidase; beta-galactosidase 2403256..2405238 Actinosynnema mirum DSM 43827 8326362 YP_003099965.1 CDS Amir_2174 NC_013093.1 2405213 2407153 D KEGG: xcv:XCV1806 hypothetical protein; hypothetical protein 2405213..2407153 Actinosynnema mirum DSM 43827 8326363 YP_003099966.1 CDS Amir_2175 NC_013093.1 2407165 2407473 D PFAM: CutA1 divalent ion tolerance protein; KEGG: bbr:BB0060 periplasmic divalent cation tolerance protein; CutA1 divalent ion tolerance protein 2407165..2407473 Actinosynnema mirum DSM 43827 8326364 YP_003099967.1 CDS Amir_2176 NC_013093.1 2407562 2407939 D PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: gur:Gura_3524 MerR family transcriptional regulator; MerR family transcriptional regulator 2407562..2407939 Actinosynnema mirum DSM 43827 8326365 YP_003099968.1 CDS Amir_2177 NC_013093.1 2408010 2408375 R hypothetical protein complement(2408010..2408375) Actinosynnema mirum DSM 43827 8326366 YP_003099969.1 CDS Amir_2178 NC_013093.1 2408563 2409540 R PFAM: beta-lactamase; KEGG: bcj:BCAM2165 beta-lactamase, class A; beta-lactamase complement(2408563..2409540) Actinosynnema mirum DSM 43827 8326367 YP_003099970.1 CDS Amir_2179 NC_013093.1 2409598 2412282 R PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: ade:Adeh_0810 hypothetical protein; FAD linked oxidase domain-containing protein complement(2409598..2412282) Actinosynnema mirum DSM 43827 8326368 YP_003099971.1 CDS Amir_2180 NC_013093.1 2412409 2413113 D TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: prw:PsycPRwf_0457 3-oxoacyl-(acyl-carrier- protein) reductase; 3-oxoacyl-(acyl-carrier-protein) reductase 2412409..2413113 Actinosynnema mirum DSM 43827 8326369 YP_003099972.1 CDS Amir_2181 NC_013093.1 2413178 2413945 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 2413178..2413945 Actinosynnema mirum DSM 43827 8326370 YP_003099973.1 CDS hemH NC_013093.1 2414041 2415075 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 2414041..2415075 Actinosynnema mirum DSM 43827 8326371 YP_003099974.1 CDS Amir_2183 NC_013093.1 2415072 2415737 D KEGG: hypothetical protein; hypothetical protein 2415072..2415737 Actinosynnema mirum DSM 43827 8326372 YP_003099975.1 CDS Amir_2184 NC_013093.1 2415795 2416568 D KEGG: bph:Bphy_2507 hypothetical protein; hypothetical protein 2415795..2416568 Actinosynnema mirum DSM 43827 8326373 YP_003099976.1 CDS Amir_2185 NC_013093.1 2416673 2417386 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: hne:HNE_0018 short chain dehydrogenase/reductase family oxidoreductase; short-chain dehydrogenase/reductase SDR complement(2416673..2417386) Actinosynnema mirum DSM 43827 8326374 YP_003099977.1 CDS Amir_2186 NC_013093.1 2417793 2418407 D KEGG: BSM; submaxillary mucin 2; hypothetical protein 2417793..2418407 Actinosynnema mirum DSM 43827 8326375 YP_003099978.1 CDS Amir_2187 NC_013093.1 2418667 2419101 D hypothetical protein 2418667..2419101 Actinosynnema mirum DSM 43827 8326376 YP_003099979.1 CDS Amir_2188 NC_013093.1 2419098 2419709 D hypothetical protein 2419098..2419709 Actinosynnema mirum DSM 43827 8326377 YP_003099980.1 CDS Amir_2189 NC_013093.1 2419713 2421077 D KEGG: GH21940 gene product from transcript GH21940- RA; hypothetical protein 2419713..2421077 Actinosynnema mirum DSM 43827 8326378 YP_003099981.1 CDS Amir_2190 NC_013093.1 2421169 2421963 D hypothetical protein 2421169..2421963 Actinosynnema mirum DSM 43827 8326379 YP_003099982.1 CDS Amir_2191 NC_013093.1 2422379 2424196 D PFAM: glycoside hydrolase family 6; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: sde:Sde_2272 cellobiohydrolase A (1 4-beta- cellobiosidase A)-like; glycoside hydrolase family protein 2422379..2424196 Actinosynnema mirum DSM 43827 8326380 YP_003099983.1 CDS Amir_2192 NC_013093.1 2424621 2426006 D KEGG: sus:Acid_2208 magnesium protoporphyrin chelatase; magnesium protoporphyrin chelatase 2424621..2426006 Actinosynnema mirum DSM 43827 8326381 YP_003099984.1 CDS Amir_2193 NC_013093.1 2426003 2427949 D SMART: von Willebrand factor type A; KEGG: aba:Acid345_3257 von Willebrand factor, type A; von Willebrand factor type A 2426003..2427949 Actinosynnema mirum DSM 43827 8326382 YP_003099985.1 CDS Amir_2194 NC_013093.1 2427952 2429133 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: GA27442 gene product from transcript GA27442- RA; ECF subfamily RNA polymerase sigma-24 subunit complement(2427952..2429133) Actinosynnema mirum DSM 43827 8326383 YP_003099986.1 CDS Amir_2195 NC_013093.1 2429225 2429695 R PFAM: NUDIX hydrolase; KEGG: eca:ECA2974 MutT-like protein; NUDIX hydrolase complement(2429225..2429695) Actinosynnema mirum DSM 43827 8326384 YP_003099987.1 CDS Amir_2197 NC_013093.1 2430700 2432268 R PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(2430700..2432268) Actinosynnema mirum DSM 43827 8326386 YP_003099988.1 CDS Amir_2198 NC_013093.1 2432446 2434215 R KEGG: bha:BH2614 cytochrome Caa3 oxidase (subunit I); TIGRFAM: cytochrome C oxidase, subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase, subunit I complement(2432446..2434215) Actinosynnema mirum DSM 43827 8326387 YP_003099989.1 CDS Amir_2201 NC_013093.1 2436340 2437578 D KEGG: afw:Anae109_2496 cysteinyl-tRNA synthetase; TIGRFAM: cysteine/1-D-myo-inosityl 2-amino-2-deoxy- alpha-D-glucopyranoside ligase; PFAM: Cysteinyl-tRNA synthetase class Ia; cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase 2436340..2437578 Actinosynnema mirum DSM 43827 8326390 YP_003099990.1 CDS Amir_2202 NC_013093.1 2437727 2439520 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proprotein convertase P; Ig family protein; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin complement(2437727..2439520) Actinosynnema mirum DSM 43827 8326391 YP_003099991.1 CDS Amir_2203 NC_013093.1 2439721 2440173 R KEGG: scl:sce6114 hypothetical protein; hypothetical protein complement(2439721..2440173) Actinosynnema mirum DSM 43827 8326392 YP_003099992.1 CDS Amir_2204 NC_013093.1 2440558 2441238 D KEGG: sus:Acid_6164 Ig family protein; hypothetical protein 2440558..2441238 Actinosynnema mirum DSM 43827 8326393 YP_003099993.1 CDS Amir_2205 NC_013093.1 2441280 2441819 D KEGG: similar to glycoprotein (predicted); hypothetical protein 2441280..2441819 Actinosynnema mirum DSM 43827 8326394 YP_003099994.1 CDS Amir_2206 NC_013093.1 2441816 2442745 D TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24 and S26 domain protein; KEGG: similar to trefoil factor; peptidase S26B, signal peptidase 2441816..2442745 Actinosynnema mirum DSM 43827 8326395 YP_003099995.1 CDS Amir_2207 NC_013093.1 2442742 2443476 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dvm:DvMF_0882 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 2442742..2443476 Actinosynnema mirum DSM 43827 8326396 YP_003099996.1 CDS Amir_2208 NC_013093.1 2443473 2443877 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: aba:Acid345_3504 response regulator receiver protein; response regulator receiver protein 2443473..2443877 Actinosynnema mirum DSM 43827 8326397 YP_003099997.1 CDS Amir_2209 NC_013093.1 2443831 2445030 R PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein; GAF sensor signal transduction histidine kinase complement(2443831..2445030) Actinosynnema mirum DSM 43827 8326398 YP_003099998.1 CDS Amir_2210 NC_013093.1 2445326 2446222 R PFAM: protein of unknown function DUF75; KEGG: sfu:Sfum_3209 hypothetical protein; hypothetical protein complement(2445326..2446222) Actinosynnema mirum DSM 43827 8326399 YP_003099999.1 CDS Amir_2211 NC_013093.1 2446273 2449809 D TIGRFAM: methionine synthase; PFAM: homocysteine S-methyltransferase; methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; dihydropteroate synthase DHPS; vitamin B12 dependent methionine synthase activation region; KEGG: gdi:GDI3502 methionine synthase; methionine synthase 2446273..2449809 Actinosynnema mirum DSM 43827 8326400 YP_003100000.1 CDS Amir_2212 NC_013093.1 2449922 2450584 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: smt:Smal_0452 HAD-superfamily hydrolase, subfamily IA, variant 3; HAD superfamily hydrolase 2449922..2450584 Actinosynnema mirum DSM 43827 8326401 YP_003100001.1 CDS Amir_2213 NC_013093.1 2450603 2451280 R PFAM: ferric iron reductase; KEGG: aav:Aave_3725 ferric iron reductase protein FhuF; ferric iron reductase complement(2450603..2451280) Actinosynnema mirum DSM 43827 8326402 YP_003100002.1 CDS Amir_2214 NC_013093.1 2451273 2451860 R PFAM: regulatory protein TetR; KEGG: acr:Acry_3038 TetR family transcriptional regulator; TetR family transcriptional regulator complement(2451273..2451860) Actinosynnema mirum DSM 43827 8326403 YP_003100003.1 CDS Amir_2215 NC_013093.1 2451964 2453187 D PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pag:PLES_23881 FMN oxidoreductase; NADH:flavin oxidoreductase/NADH oxidase 2451964..2453187 Actinosynnema mirum DSM 43827 8326404 YP_003100004.1 CDS Amir_2216 NC_013093.1 2453184 2453984 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: pau:PA14_08440 short chain alcohol dehydrogenase; short-chain dehydrogenase/reductase SDR 2453184..2453984 Actinosynnema mirum DSM 43827 8326405 YP_003100005.1 CDS Amir_2217 NC_013093.1 2454077 2454523 D KEGG: sdn:Sden_0673 hypothetical protein; hypothetical protein 2454077..2454523 Actinosynnema mirum DSM 43827 8326406 YP_003100006.1 CDS Amir_2218 NC_013093.1 2454564 2454845 D TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: xfn:XfasM23_1346 phosphoribosyl-ATP diphosphatase; phosphoribosyl-ATP diphosphatase 2454564..2454845 Actinosynnema mirum DSM 43827 8326407 YP_003100007.1 CDS Amir_2219 NC_013093.1 2454877 2455815 D PFAM: auxin Efflux Carrier; KEGG: dvm:DvMF_1323 auxin efflux carrier; auxin Efflux Carrier 2454877..2455815 Actinosynnema mirum DSM 43827 8326408 YP_003100008.1 CDS Amir_2221 NC_013093.1 2456832 2457602 R KEGG: smt:Smal_1417 hypothetical protein; hypothetical protein complement(2456832..2457602) Actinosynnema mirum DSM 43827 8326410 YP_003100009.1 CDS Amir_2222 NC_013093.1 2457731 2458624 R KEGG: hypothetical protein; RecB family exonuclease-like protein complement(2457731..2458624) Actinosynnema mirum DSM 43827 8326411 YP_003100010.1 CDS Amir_2223 NC_013093.1 2458685 2459815 D PFAM: peptidase M50; KEGG: aeh:Mlg_1368 peptidase M50; peptidase M50 2458685..2459815 Actinosynnema mirum DSM 43827 8326412 YP_003100011.1 CDS Amir_2225 NC_013093.1 2460547 2461176 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(2460547..2461176) Actinosynnema mirum DSM 43827 8326414 YP_003100012.1 CDS Amir_2226 NC_013093.1 2461212 2462324 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(2461212..2462324) Actinosynnema mirum DSM 43827 8326415 YP_003100013.1 CDS Amir_2227 NC_013093.1 2462436 2462978 D KEGG: bat:BAS2996 hypothetical protein; hypothetical protein 2462436..2462978 Actinosynnema mirum DSM 43827 8326416 YP_003100014.1 CDS Amir_2228 NC_013093.1 2463053 2463880 D PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: sfu:Sfum_2514 SAM-dependent methyltransferase; tRNA methyltransferase complex GCD14 subunit 2463053..2463880 Actinosynnema mirum DSM 43827 8326417 YP_003100015.1 CDS Amir_2229 NC_013093.1 2463949 2464839 R KEGG: scl:sce5792 hypothetical protein; hypothetical protein complement(2463949..2464839) Actinosynnema mirum DSM 43827 8326418 YP_003100016.1 CDS Amir_2230 NC_013093.1 2465044 2466003 R KEGG: scl:sce5792 hypothetical protein; hypothetical protein complement(2465044..2466003) Actinosynnema mirum DSM 43827 8326419 YP_003100017.1 CDS Amir_2231 NC_013093.1 2466722 2468521 D PFAM: ATPase AAA; SMART: ATPase AAA; KEGG: gur:Gura_2842 AAA family ATPase, CDC48 subfamily protein; ATPase AAA 2466722..2468521 Actinosynnema mirum DSM 43827 8326420 YP_003100018.1 CDS Amir_2232 NC_013093.1 2468559 2469467 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(2468559..2469467) Actinosynnema mirum DSM 43827 8326421 YP_003100019.1 CDS Amir_2233 NC_013093.1 2469464 2470537 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(2469464..2470537) Actinosynnema mirum DSM 43827 8326422 YP_003100020.1 CDS Amir_2234 NC_013093.1 2470663 2471577 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cak:Caul_1642 ABC transporter; ABC transporter 2470663..2471577 Actinosynnema mirum DSM 43827 8326423 YP_003100021.1 CDS Amir_2235 NC_013093.1 2471574 2472341 D KEGG: rpb:RPB_1462 binding-protein-dependent transport systems inner membrane component; hypothetical protein 2471574..2472341 Actinosynnema mirum DSM 43827 8326424 YP_003100022.1 CDS Amir_2236 NC_013093.1 2472380 2473294 D PFAM: aldo/keto reductase; KEGG: ank:AnaeK_3196 aldo/keto reductase; aldo/keto reductase 2472380..2473294 Actinosynnema mirum DSM 43827 8326425 YP_003100023.1 CDS Amir_2237 NC_013093.1 2473356 2473865 R PFAM: NUDIX hydrolase; KEGG: pmr:PMI1779 NUDIX hydrolase; NUDIX hydrolase complement(2473356..2473865) Actinosynnema mirum DSM 43827 8326426 YP_003100024.1 CDS Amir_2238 NC_013093.1 2474013 2476481 D PFAM: protein of unknown function DUF214; KEGG: ade:Adeh_2042 hypothetical protein; hypothetical protein 2474013..2476481 Actinosynnema mirum DSM 43827 8326427 YP_003100025.1 CDS Amir_2239 NC_013093.1 2476536 2478035 D PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; hypothetical protein 2476536..2478035 Actinosynnema mirum DSM 43827 8326428 YP_003100026.1 CDS Amir_2240 NC_013093.1 2478214 2478408 D PFAM: protein of unknown function DUF797; hypothetical protein 2478214..2478408 Actinosynnema mirum DSM 43827 8326429 YP_003100027.1 CDS Amir_2241 NC_013093.1 2478472 2479320 D PFAM: 20S proteasome A and B subunits; KEGG: GI10892 gene product from transcript GI10892- RA; 20S proteasome subunits A and B 2478472..2479320 Actinosynnema mirum DSM 43827 8326430 YP_003100028.1 CDS Amir_2242 NC_013093.1 2479365 2480156 D PFAM: 20S proteasome A and B subunits; KEGG: proteasome subunit alpha type 2; K02726 20S proteasome subunit alpha 2; 20S proteasome subunits A and B 2479365..2480156 Actinosynnema mirum DSM 43827 8326431 YP_003100029.1 CDS Amir_2243 NC_013093.1 2480214 2480768 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr4790 oxidoreductase; short-chain dehydrogenase/reductase SDR complement(2480214..2480768) Actinosynnema mirum DSM 43827 8326432 YP_003100030.1 CDS Amir_2244 NC_013093.1 2481067 2481660 D PFAM: regulatory protein TetR; KEGG: azc:AZC_1061 transcriptional regulator; TetR family transcriptional regulator 2481067..2481660 Actinosynnema mirum DSM 43827 8326433 YP_003100031.1 CDS Amir_2245 NC_013093.1 2482116 2484986 R PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; ATPase AAA; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; LuxR family transcriptional regulator complement(2482116..2484986) Actinosynnema mirum DSM 43827 8326434 YP_003100032.1 CDS Amir_2246 NC_013093.1 2485172 2486620 R PFAM: phosphoesterase PA-phosphatase related; diacylglycerol kinase catalytic region; SMART: phosphoesterase PA-phosphatase related; diacylglycerol kinase catalytic region; KEGG: scl:sce9292 hypothetical protein; PA-phosphatase-like phosphodiesterase complement(2485172..2486620) Actinosynnema mirum DSM 43827 8326435 YP_003100033.1 CDS Amir_2247 NC_013093.1 2486678 2488036 D PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; hypothetical protein 2486678..2488036 Actinosynnema mirum DSM 43827 8326436 YP_003100034.1 CDS Amir_2248 NC_013093.1 2488163 2489047 D PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: afw:Anae109_0483 activator of HSP90 ATPase 1 family protein; Activator of Hsp90 ATPase 1 family protein 2488163..2489047 Actinosynnema mirum DSM 43827 8326437 YP_003100035.1 CDS Amir_2249 NC_013093.1 2489337 2490320 D KEGG: mxa:MXAN_1359 hypothetical protein; transcriptional regulator protein 2489337..2490320 Actinosynnema mirum DSM 43827 8326438 YP_003100036.1 CDS Amir_2250 NC_013093.1 2490317 2491282 D KEGG: mxa:MXAN_1360 hypothetical protein; transcriptional regulator protein 2490317..2491282 Actinosynnema mirum DSM 43827 8326439 YP_003100037.1 CDS Amir_2251 NC_013093.1 2491567 2491911 D TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: GG15783 gene product from transcript GG15783- RA; twin-arginine translocation protein, TatA/E family subunit 2491567..2491911 Actinosynnema mirum DSM 43827 8326440 YP_003100038.1 CDS Amir_2252 NC_013093.1 2492065 2493153 D TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: nar:Saro_1096 sec-independent protein translocase TatC; Sec-independent protein translocase, TatC subunit 2492065..2493153 Actinosynnema mirum DSM 43827 8326441 YP_003100039.1 CDS Amir_2253 NC_013093.1 2493325 2494263 D PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; KEGG: mxa:MXAN_6724 lipid kinase; diacylglycerol kinase catalytic subunit 2493325..2494263 Actinosynnema mirum DSM 43827 8326442 YP_003100040.1 CDS Amir_2254 NC_013093.1 2494410 2497400 D PFAM: DEAD/DEAH box helicase domain protein; DSH domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: predicted protein; DEAD/DEAH box helicase domain-containing protein 2494410..2497400 Actinosynnema mirum DSM 43827 8326443 YP_003100041.1 CDS Amir_2255 NC_013093.1 2497519 2498205 D KEGG: scl:sce8934 hypothetical protein; hypothetical protein 2497519..2498205 Actinosynnema mirum DSM 43827 8326444 YP_003100042.1 CDS Amir_2256 NC_013093.1 2498480 2499784 D KEGG: hypothetical protein; hypothetical protein 2498480..2499784 Actinosynnema mirum DSM 43827 8326445 YP_003100043.1 CDS Amir_2257 NC_013093.1 2500259 2501308 R PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: rce:RC1_2483 DNA polymerase I; 5'-3' exonuclease complement(2500259..2501308) Actinosynnema mirum DSM 43827 8326446 YP_003100044.1 CDS Amir_2258 NC_013093.1 2501311 2502441 D PFAM: peptidase M24; creatinase; KEGG: xca:xccb100_1756 proline dipeptidase; peptidase M24 2501311..2502441 Actinosynnema mirum DSM 43827 8326447 YP_003100045.1 CDS Amir_2259 NC_013093.1 2502438 2502887 D PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: scl:sce5626 leucine responsive regulatory protein; AsnC family transcriptional regulator 2502438..2502887 Actinosynnema mirum DSM 43827 8326448 YP_003100046.1 CDS Amir_2260 NC_013093.1 2502933 2503679 R PFAM: aminotransferase class IV; KEGG: xac:XAC1291 hypothetical protein; class IV aminotransferase complement(2502933..2503679) Actinosynnema mirum DSM 43827 8326449 YP_003100047.1 CDS Amir_2261 NC_013093.1 2503900 2505099 D PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_3713 transmembrane protein; major facilitator superfamily protein 2503900..2505099 Actinosynnema mirum DSM 43827 8326450 YP_003100048.1 CDS Amir_2262 NC_013093.1 2505398 2506690 D KEGG: cvi:CV_1143 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 2505398..2506690 Actinosynnema mirum DSM 43827 8326451 YP_003100049.1 CDS Amir_2263 NC_013093.1 2506855 2510202 D KEGG: similar to CG6915-PA; hypothetical protein 2506855..2510202 Actinosynnema mirum DSM 43827 8326452 YP_003100050.1 CDS Amir_2264 NC_013093.1 2510299 2511234 R PFAM: peptidase S58 DmpA; KEGG: xau:Xaut_4121 peptidase S58 DmpA; peptidase S58 DmpA complement(2510299..2511234) Actinosynnema mirum DSM 43827 8326453 YP_003100051.1 CDS Amir_2265 NC_013093.1 2511342 2513468 D KEGG: apl:APL_1681 hypothetical protein; hypothetical protein 2511342..2513468 Actinosynnema mirum DSM 43827 8326454 YP_003100052.1 CDS Amir_2266 NC_013093.1 2513485 2515038 R PFAM: pyridoxal-dependent decarboxylase; KEGG: spe:Spro_3049 pyridoxal-dependent decarboxylase; pyridoxal-dependent decarboxylase complement(2513485..2515038) Actinosynnema mirum DSM 43827 8326455 YP_003100053.1 CDS Amir_2267 NC_013093.1 2515213 2516898 R PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: scl:sce0700 ATP-independent RNA helicase; DEAD/DEAH box helicase domain-containing protein complement(2515213..2516898) Actinosynnema mirum DSM 43827 8326456 YP_003100054.1 CDS Amir_2268 NC_013093.1 2517111 2517725 R PFAM: RelA/SpoT domain protein; KEGG: bha:BH1885 hypothetical protein; RelA/SpoT domain-containing protein complement(2517111..2517725) Actinosynnema mirum DSM 43827 8326457 YP_003100055.1 CDS Amir_2269 NC_013093.1 2517944 2518825 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: gbm:Gbem_3934 protein of unknown function DUF6 transmembrane; hypothetical protein 2517944..2518825 Actinosynnema mirum DSM 43827 8326458 YP_003100056.1 CDS Amir_2270 NC_013093.1 2519123 2519617 R hypothetical protein complement(2519123..2519617) Actinosynnema mirum DSM 43827 8326459 YP_003100057.1 CDS Amir_2271 NC_013093.1 2520093 2520635 R PFAM: YceI family protein; KEGG: afw:Anae109_3638 YceI family protein; YceI family protein complement(2520093..2520635) Actinosynnema mirum DSM 43827 8326460 YP_003100058.1 CDS Amir_2272 NC_013093.1 2520729 2521229 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rpa:RPA0821 MarR family transcriptional regulator; MarR family transcriptional regulator 2520729..2521229 Actinosynnema mirum DSM 43827 8326461 YP_003100059.1 CDS Amir_2273 NC_013093.1 2521578 2522549 D PFAM: ATPase associated with various cellular activities AAA_3; magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; KEGG: gur:Gura_0187 ATPase; ATPase 2521578..2522549 Actinosynnema mirum DSM 43827 8326462 YP_003100060.1 CDS Amir_2274 NC_013093.1 2522546 2523670 D PFAM: protein of unknown function DUF58; KEGG: scl:sce4442 hypothetical protein; hypothetical protein 2522546..2523670 Actinosynnema mirum DSM 43827 8326463 YP_003100061.1 CDS Amir_2275 NC_013093.1 2523842 2525509 D PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA1206 acetyl-coenzyme A synthetase; AMP-dependent synthetase and ligase 2523842..2525509 Actinosynnema mirum DSM 43827 8326464 YP_003100062.1 CDS Amir_2276 NC_013093.1 2525812 2526033 R hypothetical protein complement(2525812..2526033) Actinosynnema mirum DSM 43827 8326465 YP_003100063.1 CDS Amir_2277 NC_013093.1 2526257 2529535 D KEGG: reu:Reut_A0253 methylmalonyl-CoA mutase, N- terminal:methylmalonyl-CoA mutase, C-terminal; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein; ArgK protein; methylmalonyl-CoA mutase, large subunit 2526257..2529535 Actinosynnema mirum DSM 43827 8326466 YP_003100064.1 CDS Amir_2278 NC_013093.1 2529782 2530525 D PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: bid:Bind_3201 hypothetical protein; hypothetical protein 2529782..2530525 Actinosynnema mirum DSM 43827 8326467 YP_003100065.1 CDS Amir_2279 NC_013093.1 2530761 2533019 R KEGG: GH15499 gene product from transcript GH15499- RA; hypothetical protein complement(2530761..2533019) Actinosynnema mirum DSM 43827 8326468 YP_003100066.1 CDS Amir_2280 NC_013093.1 2533375 2535417 D PFAM: DNA gyrase subunit B domain protein; TOPRIM domain protein; ATP-binding region ATPase domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; KEGG: bsu:BSU00060 DNA gyrase subunit B; DNA gyrase subunit B domain-containing protein 2533375..2535417 Actinosynnema mirum DSM 43827 8326469 YP_003100067.1 CDS Amir_2281 NC_013093.1 2535438 2538869 D KEGG: bcz:BCZK0006 DNA gyrase subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; SMART: DNA gyrase/topoisomerase IV subunit A; Hedgehog/intein hint domain protein; DNA topoisomerase 2535438..2538869 Actinosynnema mirum DSM 43827 8326470 YP_003100068.1 CDS Amir_2282 NC_013093.1 2539016 2539726 D PFAM: xylose isomerase; KEGG: atc:AGR_L_3397 hypothetical protein; xylose isomerase 2539016..2539726 Actinosynnema mirum DSM 43827 8326471 YP_003100069.1 CDS Amir_2283 NC_013093.1 2539803 2540360 D KEGG: scl:sce8945 hypothetical protein; hypothetical protein 2539803..2540360 Actinosynnema mirum DSM 43827 8326472 YP_003100070.1 CDS Amir_2284 NC_013093.1 2540484 2541632 D PFAM: luciferase-like monooxygenase; KEGG: pfo:Pfl01_0703 luciferase-like; luciferase-like monooxygenase 2540484..2541632 Actinosynnema mirum DSM 43827 8326473 YP_003100071.1 CDS Amir_2285 NC_013093.1 2541629 2542222 D PFAM: NADPH-dependent FMN reductase; KEGG: rsq:Rsph17025_0771 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 2541629..2542222 Actinosynnema mirum DSM 43827 8326474 YP_003100072.1 CDS hisG NC_013093.1 2542609 2543472 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2542609..2543472 Actinosynnema mirum DSM 43827 8326475 YP_003100073.1 CDS Amir_2287 NC_013093.1 2543824 2546346 R KEGG: msl:Msil_2593 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; EAL domain protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase complement(2543824..2546346) Actinosynnema mirum DSM 43827 8326476 YP_003100074.1 CDS Amir_2288 NC_013093.1 2546957 2547448 D PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: pol:Bpro_1654 hypothetical protein; Activator of Hsp90 ATPase 1 family protein 2546957..2547448 Actinosynnema mirum DSM 43827 8326477 YP_003100075.1 CDS Amir_2289 NC_013093.1 2547608 2548195 R hypothetical protein complement(2547608..2548195) Actinosynnema mirum DSM 43827 8326478 YP_003100076.1 CDS Amir_2290 NC_013093.1 2548308 2549093 R KEGG: bcy:Bcer98_2113 hypothetical protein; hypothetical protein complement(2548308..2549093) Actinosynnema mirum DSM 43827 8326479 YP_003100077.1 CDS Amir_2291 NC_013093.1 2549090 2550697 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcy:Bcer98_2114 ABC transporter-related protein; ABC transporter complement(2549090..2550697) Actinosynnema mirum DSM 43827 8326480 YP_003100078.1 CDS Amir_2292 NC_013093.1 2550694 2551767 R PFAM: cobalt transport protein; KEGG: hha:Hhal_0811 NADH/ubiquinone/plastoquinone (complex I); cobalt transport protein complement(2550694..2551767) Actinosynnema mirum DSM 43827 8326481 YP_003100079.1 CDS Amir_2293 NC_013093.1 2551764 2551892 R hypothetical protein complement(2551764..2551892) Actinosynnema mirum DSM 43827 8326482 YP_003100080.1 CDS Amir_2294 NC_013093.1 2551889 2552758 R KEGG: MTA2; hydroxyproline-rich glycoprotein; hypothetical protein complement(2551889..2552758) Actinosynnema mirum DSM 43827 8326483 YP_003100081.1 CDS Amir_2295 NC_013093.1 2552755 2554044 R TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: hypothetical protein; LPXTG-motif cell wall anchor domain-containing protein complement(2552755..2554044) Actinosynnema mirum DSM 43827 8326484 YP_003100082.1 CDS Amir_2296 NC_013093.1 2554364 2554993 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: bur:Bcep18194_A5869 hypothetical protein; type 11 methyltransferase complement(2554364..2554993) Actinosynnema mirum DSM 43827 8326485 YP_003100083.1 CDS Amir_2297 NC_013093.1 2555032 2555436 R hypothetical protein complement(2555032..2555436) Actinosynnema mirum DSM 43827 8326486 YP_003100084.1 CDS Amir_2298 NC_013093.1 2555558 2556727 D PFAM: ROK family protein; KEGG: vei:Veis_3275 ROK family protein; ROK family protein 2555558..2556727 Actinosynnema mirum DSM 43827 8326487 YP_003100085.1 CDS Amir_2299 NC_013093.1 2557317 2558453 D PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: bha:BH0710 hypothetical protein; oxidoreductase domain-containing protein 2557317..2558453 Actinosynnema mirum DSM 43827 8326488 YP_003100086.1 CDS Amir_2300 NC_013093.1 2558507 2559511 D PFAM: xylose isomerase; AP endonuclease 2 domain protein; KEGG: vei:Veis_3268 xylose isomerase domain protein TIM barrel; xylose isomerase 2558507..2559511 Actinosynnema mirum DSM 43827 8326489 YP_003100087.1 CDS Amir_2301 NC_013093.1 2559650 2560891 D PFAM: FAD linked oxidase domain protein; D- arabinono-14-lactone oxidase; KEGG: hypothetical protein; FAD linked oxidase domain-containing protein 2559650..2560891 Actinosynnema mirum DSM 43827 8326490 YP_003100088.1 CDS Amir_2302 NC_013093.1 2561488 2562660 D PFAM: major facilitator superfamily MFS_1; KEGG: swi:Swit_4414 protein of unknown function DUF894, DitE; major facilitator superfamily protein 2561488..2562660 Actinosynnema mirum DSM 43827 8326491 YP_003100089.1 CDS Amir_2303 NC_013093.1 2562725 2562820 D hypothetical protein 2562725..2562820 Actinosynnema mirum DSM 43827 8326492 YP_003100090.1 CDS Amir_2304 NC_013093.1 2562817 2563404 D PFAM: regulatory protein TetR; KEGG: rlt:Rleg2_0103 transcriptional regulator, TetR family; TetR family transcriptional regulator 2562817..2563404 Actinosynnema mirum DSM 43827 8326493 YP_003100091.1 CDS Amir_2305 NC_013093.1 2563426 2563617 R hypothetical protein complement(2563426..2563617) Actinosynnema mirum DSM 43827 8326494 YP_003100092.1 CDS Amir_2306 NC_013093.1 2563846 2564202 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rpe:RPE_3910 anti-sigma-factor antagonist; anti-sigma-factor antagonist 2563846..2564202 Actinosynnema mirum DSM 43827 8326495 YP_003100093.1 CDS Amir_2307 NC_013093.1 2564267 2564923 D TIGRFAM: methylase; PFAM: methyltransferase small; KEGG: acp:A2cp1_0395 modification methylase, HemK family; methylase 2564267..2564923 Actinosynnema mirum DSM 43827 8326496 YP_003100094.1 CDS Amir_2308 NC_013093.1 2564958 2565125 D SMART: hypothetical protein; hypothetical protein 2564958..2565125 Actinosynnema mirum DSM 43827 8326497 YP_003100095.1 CDS Amir_2309 NC_013093.1 2565264 2566280 R KEGG: pzu:PHZ_c0782 hypothetical protein; hypothetical protein complement(2565264..2566280) Actinosynnema mirum DSM 43827 8326498 YP_003100096.1 CDS Amir_2310 NC_013093.1 2566506 2567657 R PFAM: glutamate--cysteine ligase GCS2; KEGG: dsh:Dshi_1749 carboxylate-amine ligase; glutamate--cysteine ligase GCS2 complement(2566506..2567657) Actinosynnema mirum DSM 43827 8326499 YP_003100097.1 CDS Amir_2311 NC_013093.1 2567744 2568781 R PFAM: luciferase-like monooxygenase; KEGG: bbt:BBta_7516 alkanal monooxygenase; luciferase-like monooxygenase complement(2567744..2568781) Actinosynnema mirum DSM 43827 8326500 YP_003100098.1 CDS Amir_2312 NC_013093.1 2568801 2570450 R KEGG: mxa:MXAN_2785 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS/PAC sensor signal transduction histidine kinase complement(2568801..2570450) Actinosynnema mirum DSM 43827 8326501 YP_003100099.1 CDS Amir_2313 NC_013093.1 2570477 2570764 R hypothetical protein complement(2570477..2570764) Actinosynnema mirum DSM 43827 8326502 YP_003100100.1 CDS Amir_2314 NC_013093.1 2570769 2573942 R KEGG: SNF2 superfamily protein; hypothetical protein complement(2570769..2573942) Actinosynnema mirum DSM 43827 8326503 YP_003100101.1 CDS Amir_2315 NC_013093.1 2573920 2575962 R TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: bha:BH2438 flagellar biosynthesis protein FlhA; flagellar biosynthesis protein FlhA complement(2573920..2575962) Actinosynnema mirum DSM 43827 8326504 YP_003100102.1 CDS Amir_2316 NC_013093.1 2576069 2576545 R hypothetical protein complement(2576069..2576545) Actinosynnema mirum DSM 43827 8326505 YP_003100103.1 CDS Amir_2317 NC_013093.1 2576551 2576913 R PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dds:Ddes_0324 response regulator receiver protein; response regulator receiver protein complement(2576551..2576913) Actinosynnema mirum DSM 43827 8326506 YP_003100104.1 CDS Amir_2318 NC_013093.1 2576910 2577395 R KEGG: aba:Acid345_1530 hypothetical protein; hypothetical protein complement(2576910..2577395) Actinosynnema mirum DSM 43827 8326507 YP_003100105.1 CDS Amir_2319 NC_013093.1 2577392 2577781 R PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: aba:Acid345_1527 response regulator receiver protein, CheY; response regulator receiver protein complement(2577392..2577781) Actinosynnema mirum DSM 43827 8326508 YP_003100106.1 CDS Amir_2320 NC_013093.1 2577766 2578641 R KEGG: aba:Acid345_1529 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; methyltransferase type 12; SMART: MCP methyltransferase CheR-type; CheR-type MCP methyltransferase complement(2577766..2578641) Actinosynnema mirum DSM 43827 8326509 YP_003100107.1 CDS Amir_2321 NC_013093.1 2578641 2579825 R KEGG: mmr:Mmar10_0661 chemotaxis-specific methylesterase; PFAM: CheB methylesterase; response regulator receiver; SMART: response regulator receiver; response regulator receiver modulated CheB methylesterase complement(2578641..2579825) Actinosynnema mirum DSM 43827 8326510 YP_003100108.1 CDS Amir_2322 NC_013093.1 2580177 2581037 R hypothetical protein complement(2580177..2581037) Actinosynnema mirum DSM 43827 8326511 YP_003100109.1 CDS Amir_2323 NC_013093.1 2581156 2582793 R PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1526 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(2581156..2582793) Actinosynnema mirum DSM 43827 8326512 YP_003100110.1 CDS Amir_2324 NC_013093.1 2582970 2583404 R PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: aba:Acid345_1525 CheW protein; CheW protein complement(2582970..2583404) Actinosynnema mirum DSM 43827 8326513 YP_003100111.1 CDS Amir_2325 NC_013093.1 2583407 2585689 R PFAM: CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; ATP- binding region ATPase domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: aba:Acid345_1524 CheA signal transduction histidine kinases; CheA signal transduction histidine kinase complement(2583407..2585689) Actinosynnema mirum DSM 43827 8326514 YP_003100112.1 CDS Amir_2326 NC_013093.1 2586401 2586616 R hypothetical protein complement(2586401..2586616) Actinosynnema mirum DSM 43827 8326515 YP_003100113.1 CDS Amir_2327 NC_013093.1 2586841 2587329 D KEGG: bxe:Bxe_B0776 membrane glycoprotein; hypothetical protein 2586841..2587329 Actinosynnema mirum DSM 43827 8326516 YP_003100114.1 CDS Amir_2328 NC_013093.1 2587723 2588814 R PFAM: type III secretion exporter; KEGG: cti:RALTA_B0268 FlhB: flagellar biosynthetic protein. FlhB/HrpN/YscU/SpaS family.; type III secretion exporter complement(2587723..2588814) Actinosynnema mirum DSM 43827 8326517 YP_003100115.1 CDS Amir_2329 NC_013093.1 2588822 2589592 R PFAM: type III secretion system inner membrane R protein; KEGG: tbd:Tbd_1612 flagellar biosynthesis protein FliR; type III secretion system inner membrane R protein complement(2588822..2589592) Actinosynnema mirum DSM 43827 8326518 YP_003100116.1 CDS Amir_2330 NC_013093.1 2589601 2589873 R PFAM: export protein FliQ family 3; KEGG: tgr:Tgr7_1332 flagellar biosynthetic protein FliQ; export protein FliQ family 3 complement(2589601..2589873) Actinosynnema mirum DSM 43827 8326519 YP_003100117.1 CDS fliP NC_013093.1 2589885 2590766 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(2589885..2590766) Actinosynnema mirum DSM 43827 8326520 YP_003100118.1 CDS Amir_2332 NC_013093.1 2590763 2591719 R KEGG: hypothetical protein; hypothetical protein complement(2590763..2591719) Actinosynnema mirum DSM 43827 8326521 YP_003100119.1 CDS Amir_2333 NC_013093.1 2591719 2592471 R TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: bvi:Bcep1808_0049 flagellar motor switch protein FliN; flagellar motor switch protein FliN complement(2591719..2592471) Actinosynnema mirum DSM 43827 8326522 YP_003100120.1 CDS Amir_2334 NC_013093.1 2592468 2593430 R PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; KEGG: hhe:HH1147 flagellar motor switch protein FliM; flagellar motor switch protein FliM complement(2592468..2593430) Actinosynnema mirum DSM 43827 8326523 YP_003100121.1 CDS Amir_2335 NC_013093.1 2593641 2594090 R PFAM: flagellar basal body-associated protein FliL; KEGG: rso:RSp0379 flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL complement(2593641..2594090) Actinosynnema mirum DSM 43827 8326524 YP_003100122.1 CDS Amir_2336 NC_013093.1 2594116 2595003 R PFAM: OmpA/MotB domain protein; KEGG: ppd:Ppro_3470 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein complement(2594116..2595003) Actinosynnema mirum DSM 43827 8326525 YP_003100123.1 CDS Amir_2337 NC_013093.1 2595003 2595776 R PFAM: MotA/TolQ/ExbB proton channel; KEGG: glo:Glov_0031 MotA/TolQ/ExbB proton channel; MotA/TolQ/ExbB proton channel complement(2595003..2595776) Actinosynnema mirum DSM 43827 8326526 YP_003100124.1 CDS Amir_2338 NC_013093.1 2595777 2596082 R PFAM: flagellar FlbD family protein; KEGG: bha:BH2448 hypothetical protein; flagellar FlbD family protein complement(2595777..2596082) Actinosynnema mirum DSM 43827 8326527 YP_003100125.1 CDS Amir_2339 NC_013093.1 2596215 2597045 R PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: bha:BH2449 flagellar basal body rod protein FlgG; hypothetical protein complement(2596215..2597045) Actinosynnema mirum DSM 43827 8326528 YP_003100126.1 CDS Amir_2340 NC_013093.1 2597106 2597525 R PFAM: flagellar hook capping protein; KEGG: rpe:RPE_1177 flagellar basal body rod modification protein; flagellar hook capping protein complement(2597106..2597525) Actinosynnema mirum DSM 43827 8326529 YP_003100127.1 CDS Amir_2341 NC_013093.1 2597554 2599590 R PFAM: flagellar hook-length control protein; KEGG: SNF2 superfamily protein; flagellar hook-length control protein complement(2597554..2599590) Actinosynnema mirum DSM 43827 8326530 YP_003100128.1 CDS Amir_2342 NC_013093.1 2599591 2600574 R PFAM: lytic transglycosylase catalytic; NLP/P60 protein; KEGG: bsu:BSU11570 hypothetical protein; lytic transglycosylase complement(2599591..2600574) Actinosynnema mirum DSM 43827 8326531 YP_003100129.1 CDS Amir_2343 NC_013093.1 2600571 2600999 R KEGG: bra:BRADO2721 TolA family protein; TolA family protein complement(2600571..2600999) Actinosynnema mirum DSM 43827 8326532 YP_003100130.1 CDS Amir_2344 NC_013093.1 2600996 2602315 R KEGG: afw:Anae109_2216 FliI/YscN family ATPase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: ATPase AAA; FliI/YscN family ATPase complement(2600996..2602315) Actinosynnema mirum DSM 43827 8326533 YP_003100131.1 CDS Amir_2345 NC_013093.1 2602312 2602992 R PFAM: flagellar assembly protein FliH; KEGG: azo:azo2718 flagellar assembly protein FliH; flagellar assembly protein FliH complement(2602312..2602992) Actinosynnema mirum DSM 43827 8326534 YP_003100132.1 CDS Amir_2346 NC_013093.1 2602973 2603989 R TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; KEGG: bha:BH2457 flagellar motor switch protein G; flagellar motor switch protein FliG complement(2602973..2603989) Actinosynnema mirum DSM 43827 8326535 YP_003100133.1 CDS Amir_2347 NC_013093.1 2603991 2605670 R TIGRFAM: flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring domain protein; KEGG: gbm:Gbem_3838 flagellar M-ring protein FliF; flagellar M-ring protein FliF complement(2603991..2605670) Actinosynnema mirum DSM 43827 8326536 YP_003100134.1 CDS Amir_2348 NC_013093.1 2605667 2605984 R PFAM: flagellar hook-basal body complex protein FliE; KEGG: pca:Pcar_1193 flagellar hook-basal body complex protein FliE; flagellar hook-basal body complex protein FliE complement(2605667..2605984) Actinosynnema mirum DSM 43827 8326537 YP_003100135.1 CDS Amir_2349 NC_013093.1 2605981 2606379 R PFAM: protein of unknown function DUF1078 domain protein; KEGG: efe:EFER_1855 flagellar component of cell- proximal portion of basal-body rod; hypothetical protein complement(2605981..2606379) Actinosynnema mirum DSM 43827 8326538 YP_003100136.1 CDS Amir_2350 NC_013093.1 2606381 2606737 R TIGRFAM: flagellar basal-body rod protein FlgB; KEGG: eta:ETA_20410 flagellar basal-body rod protein; flagellar basal-body rod protein FlgB complement(2606381..2606737) Actinosynnema mirum DSM 43827 8326539 YP_003100137.1 CDS Amir_2351 NC_013093.1 2607284 2607619 R hypothetical protein complement(2607284..2607619) Actinosynnema mirum DSM 43827 8326540 YP_003100138.1 CDS Amir_2352 NC_013093.1 2607616 2608014 R TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS; KEGG: pca:Pcar_1111 flagellar protein FliS; flagellar protein FliS complement(2607616..2608014) Actinosynnema mirum DSM 43827 8326541 YP_003100139.1 CDS Amir_2353 NC_013093.1 2608022 2609314 R PFAM: flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; flagellar hook- associated protein 2 domain protein; KEGG: xcb:XC_2246 flagellar protein; flagellar hook-associated 2 domain-containing protein complement(2608022..2609314) Actinosynnema mirum DSM 43827 8326542 YP_003100140.1 CDS Amir_2354 NC_013093.1 2609457 2610617 R PFAM: flagellin domain protein; KEGG: nmu:Nmul_A1337 flagellin-like; flagellin domain-containing protein complement(2609457..2610617) Actinosynnema mirum DSM 43827 8326543 YP_003100141.1 CDS Amir_2355 NC_013093.1 2611185 2612069 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 3 domain protein; KEGG: gbm:Gbem_3764 RNA polymerase, sigma 28 subunit, FliA/WhiG; FliA/WhiG subfamily RNA polymerase sigma-28 subunit complement(2611185..2612069) Actinosynnema mirum DSM 43827 8326544 YP_003100142.1 CDS Amir_2356 NC_013093.1 2612305 2612787 D PFAM: FlgN family protein; KEGG: gur:Gura_4100 hypothetical protein; FlgN family protein 2612305..2612787 Actinosynnema mirum DSM 43827 8326545 YP_003100143.1 CDS Amir_2357 NC_013093.1 2612790 2614169 D TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: ppd:Ppro_3455 flagellar hook-associated protein FlgK; flagellar hook-associated protein FlgK 2612790..2614169 Actinosynnema mirum DSM 43827 8326546 YP_003100144.1 CDS Amir_2358 NC_013093.1 2614176 2615054 D TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: gur:Gura_4098 flagellar hook-associated protein 3; flagellar hook-associated protein 3 2614176..2615054 Actinosynnema mirum DSM 43827 8326547 YP_003100145.1 CDS Amir_2359 NC_013093.1 2615051 2615563 D PFAM: protein of unknown function DUF180; KEGG: dps:DP2692 flagellar assembly protein FliW; hypothetical protein 2615051..2615563 Actinosynnema mirum DSM 43827 8326548 YP_003100146.1 CDS Amir_2360 NC_013093.1 2615517 2615777 D TIGRFAM: carbon storage regulator; PFAM: carbon storage regulator; KEGG: mca:MCA0391 carbon storage regulator; carbon storage regulator, CsrA 2615517..2615777 Actinosynnema mirum DSM 43827 8326549 YP_003100147.1 CDS Amir_2361 NC_013093.1 2616167 2617858 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proprotein convertase P; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 2616167..2617858 Actinosynnema mirum DSM 43827 8326550 YP_003100148.1 CDS Amir_2362 NC_013093.1 2617931 2619571 D KEGG: sus:Acid_3859 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; PAS/PAC sensor hybrid histidine kinase 2617931..2619571 Actinosynnema mirum DSM 43827 8326551 YP_003100149.1 CDS Amir_2363 NC_013093.1 2619568 2619948 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: rce:RC1_0432 KDP operon transcriptional regulatory protein KdpE; response regulator receiver protein 2619568..2619948 Actinosynnema mirum DSM 43827 8326552 YP_003100150.1 CDS Amir_2364 NC_013093.1 2620431 2621354 R PFAM: NmrA family protein; KEGG: sus:Acid_6298 NmrA family protein; NmrA family protein complement(2620431..2621354) Actinosynnema mirum DSM 43827 8326553 YP_003100151.1 CDS Amir_2365 NC_013093.1 2621432 2621875 R PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: mxa:MXAN_6486 transcriptional regulator, MarR family; MarR family transcriptional regulator complement(2621432..2621875) Actinosynnema mirum DSM 43827 8326554 YP_003100152.1 CDS Amir_2366 NC_013093.1 2622036 2624204 R KEGG: bmj:BMULJ_06047 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase A domain protein; ATP- binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: histidine kinase A domain protein; PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase complement(2622036..2624204) Actinosynnema mirum DSM 43827 8326555 YP_003100153.1 CDS Amir_2367 NC_013093.1 2624616 2626895 D KEGG: mag:amb2954 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase 2624616..2626895 Actinosynnema mirum DSM 43827 8326556 YP_003100154.1 CDS Amir_2368 NC_013093.1 2626892 2628103 D PFAM: Metal-dependent hydrolase HDOD; response regulator receiver; SMART: response regulator receiver; KEGG: dvu:DVU0330 response regulator; signal transduction protein 2626892..2628103 Actinosynnema mirum DSM 43827 8326557 YP_003100155.1 CDS Amir_2369 NC_013093.1 2628258 2628422 R KEGG: hypothetical protein; hypothetical protein complement(2628258..2628422) Actinosynnema mirum DSM 43827 8326558 YP_003100156.1 CDS Amir_2370 NC_013093.1 2628647 2632948 D KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein; multi-sensor hybrid histidine kinase 2628647..2632948 Actinosynnema mirum DSM 43827 8326559 YP_003100157.1 CDS Amir_2371 NC_013093.1 2633170 2634318 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: sat:SYN_01373 hydrogenase transcriptional regulatory protein; response regulator receiver protein 2633170..2634318 Actinosynnema mirum DSM 43827 8326560 YP_003100158.1 CDS Amir_2372 NC_013093.1 2634367 2635044 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pol:Bpro_0417 transcriptional regulator, GntR family; GntR family transcriptional regulator complement(2634367..2635044) Actinosynnema mirum DSM 43827 8326561 YP_003100159.1 CDS Amir_2373 NC_013093.1 2635467 2636114 D hypothetical protein 2635467..2636114 Actinosynnema mirum DSM 43827 8326562 YP_003100160.1 CDS Amir_2374 NC_013093.1 2636206 2636730 D PFAM: CHRD domain containing protein; SMART: CHRD domain containing protein; KEGG: pzu:PHZ_c0812 hypothetical protein; CHRD domain containing protein 2636206..2636730 Actinosynnema mirum DSM 43827 8326563 YP_003100161.1 CDS Amir_2375 NC_013093.1 2636829 2637188 R KEGG: bja:blr0122 hypothetical protein; hypothetical protein complement(2636829..2637188) Actinosynnema mirum DSM 43827 8326564 YP_003100162.1 CDS Amir_2376 NC_013093.1 2637274 2637786 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: efe:EFER_2801 MarR-family regulatory protein; MarR family transcriptional regulator 2637274..2637786 Actinosynnema mirum DSM 43827 8326565 YP_003100163.1 CDS Amir_2377 NC_013093.1 2637971 2638822 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; XRE family transcriptional regulator complement(2637971..2638822) Actinosynnema mirum DSM 43827 8326566 YP_003100164.1 CDS Amir_2378 NC_013093.1 2638942 2639841 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: hypothetical protein; short-chain dehydrogenase/reductase SDR 2638942..2639841 Actinosynnema mirum DSM 43827 8326567 YP_003100165.1 CDS Amir_2379 NC_013093.1 2639910 2640227 D KEGG: hypothetical protein; hypothetical protein 2639910..2640227 Actinosynnema mirum DSM 43827 8326568 YP_003100166.1 CDS Amir_2380 NC_013093.1 2640465 2642477 D KEGG: pen:PSEEN0086 alginate biosynthesis sensor protein KinB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; MASE1 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS/PAC sensor signal transduction histidine kinase 2640465..2642477 Actinosynnema mirum DSM 43827 8326569 YP_003100167.1 CDS Amir_2381 NC_013093.1 2642971 2643297 R PFAM: branched-chain amino acid transport; KEGG: pin:Ping_3723 branched-chain amino acid transport; branched-chain amino acid transport complement(2642971..2643297) Actinosynnema mirum DSM 43827 8326570 YP_003100168.1 CDS Amir_2382 NC_013093.1 2643290 2643949 R PFAM: AzlC family protein; KEGG: sbl:Sbal_4248 AzlC family protein; AzlC family protein complement(2643290..2643949) Actinosynnema mirum DSM 43827 8326571 YP_003100169.1 CDS Amir_2383 NC_013093.1 2644102 2644560 D PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: spe:Spro_3514 AsnC family transcriptional regulator; AsnC family transcriptional regulator 2644102..2644560 Actinosynnema mirum DSM 43827 8326572 YP_003100170.1 CDS Amir_2384 NC_013093.1 2644572 2645897 R PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr5567 hypothetical protein; major facilitator superfamily protein complement(2644572..2645897) Actinosynnema mirum DSM 43827 8326573 YP_003100171.1 CDS Amir_2385 NC_013093.1 2646047 2646577 D PFAM: regulatory protein TetR; KEGG: mlo:mlr3465 TetR family transcriptional regulator; TetR family transcriptional regulator 2646047..2646577 Actinosynnema mirum DSM 43827 8326574 YP_003100172.1 CDS Amir_2386 NC_013093.1 2646701 2647252 R hypothetical protein complement(2646701..2647252) Actinosynnema mirum DSM 43827 8326575 YP_003100173.1 CDS Amir_2387 NC_013093.1 2647423 2647839 R PFAM: RbsD or FucU transport; KEGG: csa:Csal_0367 RbsD or FucU transport; RbsD or FucU transport complement(2647423..2647839) Actinosynnema mirum DSM 43827 8326576 YP_003100174.1 CDS Amir_2388 NC_013093.1 2648184 2648804 D KEGG: predicted gene, 672682; hypothetical protein 2648184..2648804 Actinosynnema mirum DSM 43827 8326577 YP_003100175.1 CDS Amir_2389 NC_013093.1 2648876 2649811 R SMART: helix-turn-helix domain protein; KEGG: bac:BamMC406_3547 XRE family transcriptional regulator; helix-turn-helix domain-containing protein complement(2648876..2649811) Actinosynnema mirum DSM 43827 8326578 YP_003100176.1 CDS Amir_2390 NC_013093.1 2649898 2650608 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bpy:Bphyt_6333 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 2649898..2650608 Actinosynnema mirum DSM 43827 8326579 YP_003100177.1 CDS Amir_2391 NC_013093.1 2650679 2651008 R hypothetical protein complement(2650679..2651008) Actinosynnema mirum DSM 43827 8326580 YP_003100178.1 CDS Amir_2392 NC_013093.1 2651158 2653098 R molecular chaperone; heat shock protein 90 complement(2651158..2653098) Actinosynnema mirum DSM 43827 8326581 YP_003100179.1 CDS Amir_2393 NC_013093.1 2653747 2654220 D KEGG: rpi:Rpic_3955 transcriptional regulator, MarR family; hypothetical protein 2653747..2654220 Actinosynnema mirum DSM 43827 8326582 YP_003100180.1 CDS Amir_2394 NC_013093.1 2654409 2655014 R hypothetical protein complement(2654409..2655014) Actinosynnema mirum DSM 43827 8326583 YP_003100181.1 CDS Amir_2395 NC_013093.1 2655266 2656051 D PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: pde:Pden_1769 3-oxoacyl-(acyl-carrier- protein) reductase; short-chain dehydrogenase/reductase SDR 2655266..2656051 Actinosynnema mirum DSM 43827 8326584 YP_003100182.1 CDS Amir_2396 NC_013093.1 2656107 2656499 R hypothetical protein complement(2656107..2656499) Actinosynnema mirum DSM 43827 8326585 YP_003100183.1 CDS Amir_2397 NC_013093.1 2657193 2658218 R PFAM: luciferase-like monooxygenase; KEGG: oxidoreductase protein; luciferase-like monooxygenase complement(2657193..2658218) Actinosynnema mirum DSM 43827 8326586 YP_003100184.1 CDS Amir_2398 NC_013093.1 2658282 2658647 R PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: tcx:Tcr_0016 RNA-binding S4; RNA-binding S4 domain-containing protein complement(2658282..2658647) Actinosynnema mirum DSM 43827 8326587 YP_003100185.1 CDS Amir_2399 NC_013093.1 2658806 2659078 D KEGG: gbm:Gbem_1481 transglycosylase-associated protein; hypothetical protein 2658806..2659078 Actinosynnema mirum DSM 43827 8326588 YP_003100186.1 CDS Amir_2400 NC_013093.1 2659363 2660220 D PFAM: luciferase-like monooxygenase; KEGG: swi:Swit_2098 luciferase family protein; luciferase-like monooxygenase 2659363..2660220 Actinosynnema mirum DSM 43827 8326589 YP_003100187.1 CDS Amir_2401 NC_013093.1 2660361 2661191 D PFAM: siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: smt:Smal_2998 FAD-binding 9 siderophore- interacting domain protein; siderophore-interacting protein 2660361..2661191 Actinosynnema mirum DSM 43827 8326590 YP_003100188.1 CDS Amir_2402 NC_013093.1 2661365 2661991 D KEGG: pde:Pden_0727 MotA/TolQ/ExbB proton channel; hypothetical protein 2661365..2661991 Actinosynnema mirum DSM 43827 8326591 YP_003100189.1 CDS Amir_2403 NC_013093.1 2661981 2663120 R KEGG: aha:AHA_2314 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(2661981..2663120) Actinosynnema mirum DSM 43827 8326592 YP_003100190.1 CDS Amir_2404 NC_013093.1 2663250 2664524 D PFAM: extracellular solute-binding protein family 1; KEGG: mmw:Mmwyl1_2762 extracellular solute-binding protein; family 1 extracellular solute-binding protein 2663250..2664524 Actinosynnema mirum DSM 43827 8326593 YP_003100191.1 CDS Amir_2405 NC_013093.1 2664524 2665408 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 2664524..2665408 Actinosynnema mirum DSM 43827 8326594 YP_003100192.1 CDS Amir_2406 NC_013093.1 2665408 2666238 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL2327 transmembrane component of ABC transporter; ABC transporter inner membrane protein 2665408..2666238 Actinosynnema mirum DSM 43827 8326595 YP_003100193.1 CDS Amir_2407 NC_013093.1 2666269 2666958 R KEGG: GK24108 gene product from transcript GK24108- RA; hypothetical protein complement(2666269..2666958) Actinosynnema mirum DSM 43827 8326596 YP_003100194.1 CDS Amir_2408 NC_013093.1 2666955 2667653 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ccs:CCNA_03389 lantibiotic transport ATP- binding protein; ABC transporter complement(2666955..2667653) Actinosynnema mirum DSM 43827 8326597 YP_003100195.1 CDS Amir_2409 NC_013093.1 2667688 2668353 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(2667688..2668353) Actinosynnema mirum DSM 43827 8326598 YP_003100196.1 CDS Amir_2410 NC_013093.1 2668343 2669374 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(2668343..2669374) Actinosynnema mirum DSM 43827 8326599 YP_003100197.1 CDS Amir_2411 NC_013093.1 2669404 2669805 R hypothetical protein complement(2669404..2669805) Actinosynnema mirum DSM 43827 8326600 YP_003100198.1 CDS Amir_2412 NC_013093.1 2669919 2670635 R KEGG: bpy:Bphyt_5600 nitroreductase; hypothetical protein complement(2669919..2670635) Actinosynnema mirum DSM 43827 8326601 YP_003100199.1 CDS Amir_2413 NC_013093.1 2670845 2671405 D KEGG: hypothetical protein; hypothetical protein 2670845..2671405 Actinosynnema mirum DSM 43827 8326602 YP_003100200.1 CDS Amir_2414 NC_013093.1 2671787 2672764 R PFAM: nitroreductase; KEGG: rce:RC1_3281 hypothetical protein; nitroreductase complement(2671787..2672764) Actinosynnema mirum DSM 43827 8326603 YP_003100201.1 CDS Amir_2415 NC_013093.1 2672942 2673529 D hypothetical protein 2672942..2673529 Actinosynnema mirum DSM 43827 8326604 YP_003100202.1 CDS Amir_2416 NC_013093.1 2673623 2674456 D PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 2673623..2674456 Actinosynnema mirum DSM 43827 8326605 YP_003100203.1 CDS Amir_2417 NC_013093.1 2674578 2675423 R KEGG: zmo:ZMO1569 pyruvate-formate lyase activating enzyme; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; pyruvate formate-lyase activating enzyme complement(2674578..2675423) Actinosynnema mirum DSM 43827 8326606 YP_003100204.1 CDS Amir_2418 NC_013093.1 2675503 2677761 R KEGG: rru:Rru_A3000 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C- acetyltransferase glycine radical; formate acetyltransferase complement(2675503..2677761) Actinosynnema mirum DSM 43827 8326607 YP_003100205.1 CDS Amir_2419 NC_013093.1 2678072 2680069 R KEGG: ade:Adeh_0129 methyltransferase type 11; hypothetical protein complement(2678072..2680069) Actinosynnema mirum DSM 43827 8326608 YP_003100206.1 CDS Amir_2420 NC_013093.1 2680236 2680628 R hypothetical protein complement(2680236..2680628) Actinosynnema mirum DSM 43827 8326609 YP_003100207.1 CDS Amir_2421 NC_013093.1 2680859 2690980 D TIGRFAM: hypothetical protein; PFAM: Cna B domain protein; protein of unknown function DUF11; KEGG: colA; Cna B-type domain-containing protein; hypothetical protein 2680859..2690980 Actinosynnema mirum DSM 43827 8326610 YP_003100208.1 CDS Amir_2422 NC_013093.1 2691116 2691808 R PFAM: regulatory protein TetR; KEGG: rso:RS05498 transcription regulator protein; TetR family transcriptional regulator complement(2691116..2691808) Actinosynnema mirum DSM 43827 8326611 YP_003100209.1 CDS Amir_2423 NC_013093.1 2691969 2692757 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: scl:sce6363 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 2691969..2692757 Actinosynnema mirum DSM 43827 8326612 YP_003100210.1 CDS Amir_2424 NC_013093.1 2692908 2693117 D hypothetical protein 2692908..2693117 Actinosynnema mirum DSM 43827 8326613 YP_003100211.1 CDS Amir_2425 NC_013093.1 2693123 2694754 R KEGG: prw:PsycPRwf_0069 cholesterol oxidase; Cholesterol oxidase complement(2693123..2694754) Actinosynnema mirum DSM 43827 8326614 YP_003100212.1 CDS Amir_2426 NC_013093.1 2694882 2695691 R PFAM: Ion transport protein; KEGG: tmz:Tmz1t_1575 ion transport protein; Ion transport protein complement(2694882..2695691) Actinosynnema mirum DSM 43827 8326615 YP_003100213.1 CDS Amir_2427 NC_013093.1 2696045 2696848 D PFAM: alpha/beta hydrolase fold; KEGG: rlt:Rleg2_6302 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 2696045..2696848 Actinosynnema mirum DSM 43827 8326616 YP_003100214.1 CDS Amir_2428 NC_013093.1 2696845 2698212 D PFAM: FAD linked oxidase domain protein; KEGG: scl:sce0752 glycolate oxidase; FAD linked oxidase domain-containing protein 2696845..2698212 Actinosynnema mirum DSM 43827 8326617 YP_003100215.1 CDS Amir_2429 NC_013093.1 2698252 2698437 R PFAM: protein of unknown function DUF397; hypothetical protein complement(2698252..2698437) Actinosynnema mirum DSM 43827 8326618 YP_003100216.1 CDS Amir_2430 NC_013093.1 2698440 2699270 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: rlt:Rleg2_3945 transcriptional regulator, XRE family; XRE family transcriptional regulator complement(2698440..2699270) Actinosynnema mirum DSM 43827 8326619 YP_003100217.1 CDS Amir_2431 NC_013093.1 2699524 2699967 D KEGG: hypothetical protein; hypothetical protein 2699524..2699967 Actinosynnema mirum DSM 43827 8326620 YP_003100218.1 CDS Amir_2432 NC_013093.1 2699992 2700807 R hypothetical protein complement(2699992..2700807) Actinosynnema mirum DSM 43827 8326621 YP_003100219.1 CDS Amir_2433 NC_013093.1 2701011 2701178 D hypothetical protein 2701011..2701178 Actinosynnema mirum DSM 43827 8326622 YP_003100220.1 CDS Amir_2434 NC_013093.1 2701231 2702121 R PFAM: hypothetical protein; KEGG: nmu:Nmul_A2438 hypothetical protein; hypothetical protein complement(2701231..2702121) Actinosynnema mirum DSM 43827 8326623 YP_003100221.1 CDS Amir_2435 NC_013093.1 2702403 2703164 R PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: aba:Acid345_0656 transcriptional regulator, DeoR family; DeoR family transcriptional regulator complement(2702403..2703164) Actinosynnema mirum DSM 43827 8326624 YP_003100222.1 CDS Amir_2436 NC_013093.1 2703327 2704814 D PFAM: sodium/hydrogen exchanger; KEGG: mrd:Mrad2831_1143 Na+/H+ antiporter; sodium/hydrogen exchanger 2703327..2704814 Actinosynnema mirum DSM 43827 8326625 YP_003100223.1 CDS Amir_2437 NC_013093.1 2704818 2708651 R KEGG: rru:Rru_A1270 hypothetical protein; hypothetical protein complement(2704818..2708651) Actinosynnema mirum DSM 43827 8326626 YP_003100224.1 CDS Amir_2438 NC_013093.1 2708651 2709868 R PFAM: metallophosphoesterase; KEGG: scl:sce7166 DNA repair exonuclease family protein; metallophosphoesterase complement(2708651..2709868) Actinosynnema mirum DSM 43827 8326627 YP_003100225.1 CDS Amir_2439 NC_013093.1 2710155 2711507 D KEGG: ade:Adeh_1847 chromosome segregation ATPase; chromosome segregation ATPase 2710155..2711507 Actinosynnema mirum DSM 43827 8326628 YP_003100226.1 CDS Amir_2440 NC_013093.1 2711510 2712070 D hypothetical protein 2711510..2712070 Actinosynnema mirum DSM 43827 8326629 YP_003100227.1 CDS Amir_2441 NC_013093.1 2712111 2712938 R SMART: helix-turn-helix domain protein; KEGG: bja:bll4873 hypothetical protein; XRE family transcriptional regulator complement(2712111..2712938) Actinosynnema mirum DSM 43827 8326630 YP_003100228.1 CDS Amir_2442 NC_013093.1 2713056 2713859 D PFAM: siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: jan:Jann_2126 FAD-binding 9, siderophore- interacting; siderophore-interacting protein 2713056..2713859 Actinosynnema mirum DSM 43827 8326631 YP_003100229.1 CDS Amir_2443 NC_013093.1 2713910 2714599 R PFAM: regulatory protein TetR; KEGG: rpb:RPB_4514 TetR family transcriptional regulator; TetR family transcriptional regulator complement(2713910..2714599) Actinosynnema mirum DSM 43827 8326632 YP_003100230.1 CDS Amir_2444 NC_013093.1 2714725 2715663 D PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: ccs:CCNA_02438 quinone oxidoreductase; alcohol dehydrogenase GroES domain-containing protein 2714725..2715663 Actinosynnema mirum DSM 43827 8326633 YP_003100231.1 CDS Amir_2445 NC_013093.1 2716193 2717641 D KEGG: scl:sce8913 cytochrome P450 CYP109C2; cytochrome P450-like protein 2716193..2717641 Actinosynnema mirum DSM 43827 8326634 YP_003100232.1 CDS Amir_2446 NC_013093.1 2717664 2718590 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pmy:Pmen_4546 LysR family transcriptional regulator; LysR family transcriptional regulator complement(2717664..2718590) Actinosynnema mirum DSM 43827 8326635 YP_003100233.1 CDS Amir_2447 NC_013093.1 2718664 2719629 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: dvm:DvMF_1193 protein of unknown function DUF6 transmembrane; hypothetical protein 2718664..2719629 Actinosynnema mirum DSM 43827 8326636 YP_003100234.1 CDS Amir_2448 NC_013093.1 2719922 2720512 D PFAM: protein of unknown function UPF0016; KEGG: sat:SYN_01349 hypothetical protein; hypothetical protein 2719922..2720512 Actinosynnema mirum DSM 43827 8326637 YP_003100235.1 CDS Amir_2449 NC_013093.1 2720610 2720960 R hypothetical protein complement(2720610..2720960) Actinosynnema mirum DSM 43827 8326638 YP_003100236.1 CDS Amir_2450 NC_013093.1 2720974 2721219 R KEGG: mag:amb4032 hypothetical protein; hypothetical protein complement(2720974..2721219) Actinosynnema mirum DSM 43827 8326639 YP_003100237.1 CDS Amir_2451 NC_013093.1 2721804 2722385 D hypothetical protein 2721804..2722385 Actinosynnema mirum DSM 43827 8326640 YP_003100238.1 CDS Amir_2452 NC_013093.1 2722414 2722833 D hypothetical protein 2722414..2722833 Actinosynnema mirum DSM 43827 8326641 YP_003100239.1 CDS Amir_2453 NC_013093.1 2722916 2723215 R KEGG: gbm:Gbem_1185 hypothetical protein; hypothetical protein complement(2722916..2723215) Actinosynnema mirum DSM 43827 8326642 YP_003100240.1 CDS Amir_2454 NC_013093.1 2723427 2723933 R PFAM: regulatory protein MarR; transcriptional regulator PadR family protein; SMART: regulatory protein MarR; KEGG: atc:AGR_C_466 hypothetical protein; MarR family transcriptional regulator complement(2723427..2723933) Actinosynnema mirum DSM 43827 8326643 YP_003100241.1 CDS Amir_2455 NC_013093.1 2723976 2725064 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: reh:H16_A0077 predicted PecM protein; hypothetical protein 2723976..2725064 Actinosynnema mirum DSM 43827 8326644 YP_003100242.1 CDS Amir_2456 NC_013093.1 2724904 2726604 R PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: rsq:Rsph17025_3273 acetamidase/formamidase; ABC transporter complement(2724904..2726604) Actinosynnema mirum DSM 43827 8326645 YP_003100243.1 CDS Amir_2457 NC_013093.1 2726601 2728289 R PFAM: extracellular solute-binding protein family 5; KEGG: gbe:GbCGDNIH1_0125 amide-UreA binding protein; family 5 extracellular solute-binding protein complement(2726601..2728289) Actinosynnema mirum DSM 43827 8326646 YP_003100244.1 CDS Amir_2458 NC_013093.1 2728410 2729405 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsh:Rsph17029_4148 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein complement(2728410..2729405) Actinosynnema mirum DSM 43827 8326647 YP_003100245.1 CDS Amir_2459 NC_013093.1 2729405 2730331 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pca:Pcar_1867 ABC-type transport system protein; ABC transporter inner membrane protein complement(2729405..2730331) Actinosynnema mirum DSM 43827 8326648 YP_003100246.1 CDS Amir_2460 NC_013093.1 2730551 2730916 D PFAM: helix-turn-helix HxlR type; KEGG: transcriptional regulator, HxlR family; HxlR family transcriptional regulator 2730551..2730916 Actinosynnema mirum DSM 43827 8326649 YP_003100247.1 CDS Amir_2461 NC_013093.1 2731034 2731993 D PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: ank:AnaeK_3358 alcohol dehydrogenase zinc- binding domain protein; alcohol dehydrogenase GroES domain-containing protein 2731034..2731993 Actinosynnema mirum DSM 43827 8326650 YP_003100248.1 CDS Amir_2462 NC_013093.1 2732004 2732276 D hypothetical protein 2732004..2732276 Actinosynnema mirum DSM 43827 8326651 YP_003100249.1 CDS Amir_2463 NC_013093.1 2732315 2733151 D hypothetical protein 2732315..2733151 Actinosynnema mirum DSM 43827 8326652 YP_003100250.1 CDS Amir_2464 NC_013093.1 2733130 2733819 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: rce:RC1_3267 phosphate regulon transcriptional regulatory protein PhoB; winged helix family two component transcriptional regulator complement(2733130..2733819) Actinosynnema mirum DSM 43827 8326653 YP_003100251.1 CDS Amir_2465 NC_013093.1 2734048 2735841 D PFAM: histidine kinase A domain protein; ATP- binding region ATPase domain protein; SMART: histidine kinase A domain protein; ATP- binding region ATPase domain protein; KEGG: scl:sce2655 two-component hybrid sensor and regulator; histidine kinase 2734048..2735841 Actinosynnema mirum DSM 43827 8326654 YP_003100252.1 CDS Amir_2466 NC_013093.1 2735872 2736234 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sat:SYN_02356 anti-sigma F factor antagonist; anti-sigma-factor antagonist 2735872..2736234 Actinosynnema mirum DSM 43827 8326655 YP_003100253.1 CDS Amir_2467 NC_013093.1 2737302 2740496 R PFAM: glycoside hydrolase family 2 sugar binding; PA14 domain protein; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; SMART: PA14 domain protein; LamG domain protein jellyroll fold domain protein; KEGG: sus:Acid_6668 glycoside hydrolase family protein; glycoside hydrolase family protein complement(2737302..2740496) Actinosynnema mirum DSM 43827 8326656 YP_003100254.1 CDS Amir_2468 NC_013093.1 2740664 2741857 R PFAM: major facilitator superfamily MFS_1; KEGG: maq:Maqu_2048 major facilitator superfamily transporter; major facilitator superfamily protein complement(2740664..2741857) Actinosynnema mirum DSM 43827 8326657 YP_003100255.1 CDS Amir_2469 NC_013093.1 2741857 2742531 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: met:M446_5037 GntR family transcriptional regulator; GntR family transcriptional regulator complement(2741857..2742531) Actinosynnema mirum DSM 43827 8326658 YP_003100256.1 CDS Amir_2470 NC_013093.1 2742765 2743412 D KEGG: GF15944 gene product from transcript GF15944- RA; hypothetical protein 2742765..2743412 Actinosynnema mirum DSM 43827 8326659 YP_003100257.1 CDS Amir_2471 NC_013093.1 2743541 2744023 D hypothetical protein 2743541..2744023 Actinosynnema mirum DSM 43827 8326660 YP_003100258.1 CDS Amir_2472 NC_013093.1 2744408 2744785 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dvl:Dvul_2983 anti-sigma-factor antagonist; anti-sigma-factor antagonist 2744408..2744785 Actinosynnema mirum DSM 43827 8326661 YP_003100259.1 CDS Amir_2473 NC_013093.1 2744793 2745863 D PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: dvl:Dvul_0672 peptidase M20; peptidase M20 2744793..2745863 Actinosynnema mirum DSM 43827 8326662 YP_003100260.1 CDS Amir_2474 NC_013093.1 2745993 2746391 D KEGG: afw:Anae109_0106 integral membrane sensor signal transduction histidine kinase; hypothetical protein 2745993..2746391 Actinosynnema mirum DSM 43827 8326663 YP_003100261.1 CDS Amir_2475 NC_013093.1 2746697 2747368 D PFAM: chitin-binding domain 3 protein; KEGG: sml:Smlt4515 cellulose/chitin- binding protein; chitin-binding domain 3 protein 2746697..2747368 Actinosynnema mirum DSM 43827 8326664 YP_003100262.1 CDS Amir_2476 NC_013093.1 2747665 2748669 D PFAM: integral membrane protein TerC; KEGG: csa:Csal_1104 integral membrane protein TerC; integral membrane protein TerC 2747665..2748669 Actinosynnema mirum DSM 43827 8326665 YP_003100263.1 CDS Amir_2477 NC_013093.1 2748907 2749524 D PFAM: isochorismatase hydrolase; KEGG: bid:Bind_1386 isochorismatase hydrolase; isochorismatase hydrolase 2748907..2749524 Actinosynnema mirum DSM 43827 8326666 YP_003100264.1 CDS Amir_2478 NC_013093.1 2749604 2750794 D PFAM: peptidoglycan-binding domain 1 protein; KEGG: mes:Meso_0085 peptidoglycan-binding domain 1; peptidoglycan-binding domain 1 protein 2749604..2750794 Actinosynnema mirum DSM 43827 8326667 YP_003100265.1 CDS Amir_2479 NC_013093.1 2751287 2751550 D hypothetical protein 2751287..2751550 Actinosynnema mirum DSM 43827 8326668 YP_003100266.1 CDS Amir_2480 NC_013093.1 2751597 2752313 R KEGG: rso:RS02209 transmembrane protein; integral membrane protein complement(2751597..2752313) Actinosynnema mirum DSM 43827 8326669 YP_003100267.1 CDS Amir_2481 NC_013093.1 2752855 2764620 D TIGRFAM: hypothetical protein; PFAM: protein of unknown function DUF11; KEGG: bce:BC1592 cell surface protein; hypothetical protein 2752855..2764620 Actinosynnema mirum DSM 43827 8326670 YP_003100268.1 CDS Amir_2482 NC_013093.1 2764713 2765351 D hypothetical protein 2764713..2765351 Actinosynnema mirum DSM 43827 8326671 YP_003100269.1 CDS Amir_2483 NC_013093.1 2766687 2768600 D KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein 2766687..2768600 Actinosynnema mirum DSM 43827 8326672 YP_003100270.1 CDS Amir_2484 NC_013093.1 2768704 2770383 R SMART: von Willebrand factor type A; KEGG: dac:Daci_0766 von Willebrand factor type A; von Willebrand factor type A complement(2768704..2770383) Actinosynnema mirum DSM 43827 8326673 YP_003100271.1 CDS Amir_2485 NC_013093.1 2770371 2771597 R KEGG: dac:Daci_0764 hypothetical protein; hypothetical protein complement(2770371..2771597) Actinosynnema mirum DSM 43827 8326674 YP_003100272.1 CDS Amir_2486 NC_013093.1 2771601 2772374 R hypothetical protein complement(2771601..2772374) Actinosynnema mirum DSM 43827 8326675 YP_003100273.1 CDS Amir_2487 NC_013093.1 2772405 2773538 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: ank:AnaeK_0122 serine/threonine protein kinase; serine/threonine protein kinase complement(2772405..2773538) Actinosynnema mirum DSM 43827 8326676 YP_003100274.1 CDS Amir_2490 NC_013093.1 2776059 2776721 D KEGG: rce:RC1_0257 puromycin N-acetyltransferase; hypothetical protein 2776059..2776721 Actinosynnema mirum DSM 43827 8326679 YP_003100275.1 CDS Amir_2491 NC_013093.1 2776775 2777878 R KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 complement(2776775..2777878) Actinosynnema mirum DSM 43827 8326680 YP_003100276.1 CDS Amir_2492 NC_013093.1 2778236 2780008 D TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: eca:ECA1488 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 2778236..2780008 Actinosynnema mirum DSM 43827 8326681 YP_003100277.1 CDS Amir_2493 NC_013093.1 2780680 2787840 D PFAM: beta-ketoacyl synthase; acyl transferase; KR domain protein; short-chain dehydrogenase/reductase SDR; 2- nitropropane dioxygenase NPD; phosphopantetheine-binding; KEGG: sus:Acid_1972 beta-ketoacyl synthase; erythronolide synthase 2780680..2787840 Actinosynnema mirum DSM 43827 8326682 YP_003100278.1 CDS Amir_2494 NC_013093.1 2787837 2792198 D PFAM: beta-ketoacyl synthase; acyl transferase; 4'- phosphopantetheinyl transferase; KEGG: sus:Acid_1973 beta-ketoacyl synthase; beta-ketoacyl synthase 2787837..2792198 Actinosynnema mirum DSM 43827 8326683 YP_003100279.1 CDS Amir_2495 NC_013093.1 2792195 2792509 D KEGG: pub:SAR11_0708 acyl carrier protein (ACP); hypothetical protein 2792195..2792509 Actinosynnema mirum DSM 43827 8326684 YP_003100280.1 CDS Amir_2496 NC_013093.1 2792506 2793339 D PFAM: alpha/beta hydrolase fold; KEGG: azc:AZC_1444 beta-ketoadipate enol-lactone hydrolase protein; alpha/beta hydrolase fold protein 2792506..2793339 Actinosynnema mirum DSM 43827 8326685 YP_003100281.1 CDS Amir_2497 NC_013093.1 2793336 2794478 D TIGRFAM: glycosyltransferase, MGT family; PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; KEGG: bcm:Bcenmc03_1778 glycosyl transferase family protein; MGT family glycosyltransferase 2793336..2794478 Actinosynnema mirum DSM 43827 8326686 YP_003100282.1 CDS Amir_2498 NC_013093.1 2794856 2796643 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rce:RC1_1837 ABC transporter, ATP-binding; ABC transporter 2794856..2796643 Actinosynnema mirum DSM 43827 8326687 YP_003100283.1 CDS Amir_2499 NC_013093.1 2796627 2797445 R PFAM: lipolytic protein G-D-S-L family; KEGG: nar:Saro_1805 hypothetical protein; G-D-S-L family lipolytic protein complement(2796627..2797445) Actinosynnema mirum DSM 43827 8326688 YP_003100284.1 CDS Amir_2500 NC_013093.1 2797651 2799537 D PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mxa:MXAN_0345 N-acetylmuramoyl-L- alanine amidase; N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD 2797651..2799537 Actinosynnema mirum DSM 43827 8326689 YP_003100285.1 CDS Amir_2501 NC_013093.1 2799627 2800091 D SMART: CHRD domain containing protein; KEGG: scl:sce5878 hypothetical protein; CHRD domain containing protein 2799627..2800091 Actinosynnema mirum DSM 43827 8326690 YP_003100286.1 CDS Amir_2502 NC_013093.1 2800252 2800797 D hypothetical protein 2800252..2800797 Actinosynnema mirum DSM 43827 8326691 YP_003100287.1 CDS Amir_2503 NC_013093.1 2800895 2801263 D PFAM: YCII-related; KEGG: scl:sce5148 hypothetical protein; YCII-like protein 2800895..2801263 Actinosynnema mirum DSM 43827 8326692 YP_003100288.1 CDS Amir_2504 NC_013093.1 2801278 2802510 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: sus:Acid_3701 RNA polymerase ECF-subfamily sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 2801278..2802510 Actinosynnema mirum DSM 43827 8326693 YP_003100289.1 CDS Amir_2505 NC_013093.1 2802500 2803240 R KEGG: scl:sce4774 peptidase M10A; peptidase M10A complement(2802500..2803240) Actinosynnema mirum DSM 43827 8326694 YP_003100290.1 CDS Amir_2506 NC_013093.1 2803691 2805142 R PFAM: Aldehyde Dehydrogenase; KEGG: bcm:Bcenmc03_6120 aldehyde dehydrogenase; aldehyde dehydrogenase complement(2803691..2805142) Actinosynnema mirum DSM 43827 8326695 YP_003100291.1 CDS Amir_2507 NC_013093.1 2805587 2806441 D hypothetical protein 2805587..2806441 Actinosynnema mirum DSM 43827 8326696 YP_003100292.1 CDS Amir_2508 NC_013093.1 2806438 2811342 D KEGG: acp:A2cp1_3940 hypothetical protein; hypothetical protein 2806438..2811342 Actinosynnema mirum DSM 43827 8326697 YP_003100293.1 CDS Amir_2509 NC_013093.1 2811339 2816237 D KEGG: hypothetical protein; hypothetical protein 2811339..2816237 Actinosynnema mirum DSM 43827 8326698 YP_003100294.1 CDS Amir_2510 NC_013093.1 2816234 2821168 D KEGG: MUC17; mucin 17, cell surface associated; hypothetical protein 2816234..2821168 Actinosynnema mirum DSM 43827 8326699 YP_003100295.1 CDS Amir_2511 NC_013093.1 2821165 2822322 D PFAM: ATPase associated with various cellular activities AAA_5; ATPase associated with various cellular activities AAA_3; SMART: ATPase AAA; KEGG: mrd:Mrad2831_1397 ATPase; ATPase 2821165..2822322 Actinosynnema mirum DSM 43827 8326700 YP_003100296.1 CDS Amir_2512 NC_013093.1 2822336 2826223 D PFAM: VWA containing CoxE family protein; KEGG: ecs:ECs2930 hypothetical protein; VWA containing CoxE family protein 2822336..2826223 Actinosynnema mirum DSM 43827 8326701 YP_003100297.1 CDS Amir_2513 NC_013093.1 2826220 2827986 D KEGG: mrd:Mrad2831_1392 zinc finger SWIM domain- containing protein; hypothetical protein 2826220..2827986 Actinosynnema mirum DSM 43827 8326702 YP_003100298.1 CDS Amir_2514 NC_013093.1 2828329 2829081 D hypothetical protein 2828329..2829081 Actinosynnema mirum DSM 43827 8326703 YP_003100299.1 CDS Amir_2515 NC_013093.1 2829103 2829990 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce1222 AraC-like transcription regulator; AraC family transcriptional regulator complement(2829103..2829990) Actinosynnema mirum DSM 43827 8326704 YP_003100300.1 CDS Amir_2516 NC_013093.1 2830263 2830820 R PFAM: DoxX family protein; KEGG: mes:Meso_2920 DoxX; DoxX family protein complement(2830263..2830820) Actinosynnema mirum DSM 43827 8326705 YP_003100301.1 CDS Amir_2517 NC_013093.1 2831131 2833398 D PFAM: Catalase domain protein; KEGG: psa:PST_0039 hydroperoxidase II; Catalase 2831131..2833398 Actinosynnema mirum DSM 43827 8326706 YP_003100302.1 CDS Amir_2518 NC_013093.1 2833648 2834103 D PFAM: endoribonuclease L-PSP; KEGG: hypothetical protein; endoribonuclease L-PSP 2833648..2834103 Actinosynnema mirum DSM 43827 8326707 YP_003100303.1 CDS Amir_2519 NC_013093.1 2834125 2834976 R TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: phenazine biosynthesis PhzC/PhzF protein; KEGG: psb:Psyr_3359 phenazine biosynthesis PhzC/PhzF protein; phenazine biosynthesis protein PhzF family complement(2834125..2834976) Actinosynnema mirum DSM 43827 8326708 YP_003100304.1 CDS Amir_2520 NC_013093.1 2835009 2835860 R SMART: prolyl 4-hydroxylase alpha subunit; KEGG: bha:BH2933 hypothetical protein; prolyl 4-hydroxylase alpha subunit complement(2835009..2835860) Actinosynnema mirum DSM 43827 8326709 YP_003100305.1 CDS Amir_2521 NC_013093.1 2835963 2836151 R hypothetical protein complement(2835963..2836151) Actinosynnema mirum DSM 43827 8326710 YP_003100306.1 CDS Amir_2522 NC_013093.1 2836290 2839166 R PFAM: hypothetical protein; KEGG: hypothetical protein; hypothetical protein complement(2836290..2839166) Actinosynnema mirum DSM 43827 8326711 YP_003100307.1 CDS Amir_2523 NC_013093.1 2839358 2841013 R PFAM: major facilitator superfamily MFS_1; KEGG: bph:Bphy_3357 EmrB/QacA family drug resistance transporter; major facilitator superfamily protein complement(2839358..2841013) Actinosynnema mirum DSM 43827 8326712 YP_003100308.1 CDS Amir_2524 NC_013093.1 2841010 2841495 R PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: ppw:PputW619_3117 MarR family transcriptional regulator; MarR family transcriptional regulator complement(2841010..2841495) Actinosynnema mirum DSM 43827 8326713 YP_003100309.1 CDS Amir_2525 NC_013093.1 2841606 2842208 D PFAM: regulatory protein TetR; KEGG: transcriptional regulator protein; TetR family transcriptional regulator 2841606..2842208 Actinosynnema mirum DSM 43827 8326714 YP_003100310.1 CDS Amir_2526 NC_013093.1 2842333 2843328 D PFAM: intradiol ring-cleavage dioxygenase; KEGG: dac:Daci_3143 intradiol ring-cleavage dioxygenase; intradiol ring-cleavage dioxygenase 2842333..2843328 Actinosynnema mirum DSM 43827 8326715 YP_003100311.1 CDS Amir_2528 NC_013093.1 2844590 2845471 D PFAM: transcription activator effector binding; regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcb:BCB4264_A2545 transcriptional regulator, MerR family; MerR family transcriptional regulator 2844590..2845471 Actinosynnema mirum DSM 43827 8326717 YP_003100312.1 CDS Amir_2529 NC_013093.1 2845611 2848967 R PFAM: metallophosphoesterase; KEGG: xcb:XC_4140 hypothetical protein; metallophosphoesterase complement(2845611..2848967) Actinosynnema mirum DSM 43827 8326718 YP_003100313.1 CDS Amir_2530 NC_013093.1 2849112 2850677 D KEGG: mxa:MXAN_5493 WD domain G-beta repeat protein; hypothetical protein 2849112..2850677 Actinosynnema mirum DSM 43827 8326719 YP_003100314.1 CDS Amir_2531 NC_013093.1 2850763 2853039 D PFAM: tyrosine protein kinase; SMART: serine/threonine protein kinase; KEGG: scl:sce5109 protein kinase; serine/threonine protein kinase 2850763..2853039 Actinosynnema mirum DSM 43827 8326720 YP_003100315.1 CDS Amir_2532 NC_013093.1 2853120 2854514 D PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: mpo:Mpop_1395 LPXTG-motif cell wall anchor domain protein; von Willebrand factor type A 2853120..2854514 Actinosynnema mirum DSM 43827 8326721 YP_003100316.1 CDS Amir_2533 NC_013093.1 2854511 2855647 D KEGG: GK23348 gene product from transcript GK23348- RA; hypothetical protein 2854511..2855647 Actinosynnema mirum DSM 43827 8326722 YP_003100317.1 CDS Amir_2534 NC_013093.1 2855727 2856941 D PFAM: extracellular solute-binding protein family 1; KEGG: ret:RHE_CH00696 alpha-glucoside ABC transporter, substrate-binding protein; family 1 extracellular solute-binding protein 2855727..2856941 Actinosynnema mirum DSM 43827 8326723 YP_003100318.1 CDS Amir_2535 NC_013093.1 2857177 2858448 D PFAM: cytochrome P450; KEGG: hypothetical protein; cytochrome P450 2857177..2858448 Actinosynnema mirum DSM 43827 8326724 YP_003100319.1 CDS Amir_2536 NC_013093.1 2858482 2859270 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr7343 short-chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(2858482..2859270) Actinosynnema mirum DSM 43827 8326725 YP_003100320.1 CDS Amir_2537 NC_013093.1 2859347 2860582 D PFAM: major facilitator superfamily MFS_1; KEGG: efe:EFER_2257 lactose/glucose efflux system; major facilitator superfamily protein 2859347..2860582 Actinosynnema mirum DSM 43827 8326726 YP_003100321.1 CDS Amir_2538 NC_013093.1 2860636 2861100 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: mag:amb1485 transcriptional regulator; MarR family transcriptional regulator 2860636..2861100 Actinosynnema mirum DSM 43827 8326727 YP_003100322.1 CDS Amir_2539 NC_013093.1 2861017 2861829 R KEGG: hypothetical protein LOC743833; hypothetical protein complement(2861017..2861829) Actinosynnema mirum DSM 43827 8326728 YP_003100323.1 CDS Amir_2540 NC_013093.1 2861875 2865831 R PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: ABR142Wp; K01529; DEAD/DEAH box helicase domain-containing protein complement(2861875..2865831) Actinosynnema mirum DSM 43827 8326729 YP_003100324.1 CDS Amir_2541 NC_013093.1 2865926 2866402 R KEGG: hch:HCH_03911 hypothetical protein; hypothetical protein complement(2865926..2866402) Actinosynnema mirum DSM 43827 8326730 YP_003100325.1 CDS Amir_2542 NC_013093.1 2866515 2866982 D PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: aha:AHA_0491 AsnC family transcriptional regulator; AsnC family transcriptional regulator 2866515..2866982 Actinosynnema mirum DSM 43827 8326731 YP_003100326.1 CDS Amir_2543 NC_013093.1 2866979 2867818 D KEGG: scl:sce1853 hypothetical protein; hypothetical protein 2866979..2867818 Actinosynnema mirum DSM 43827 8326732 YP_003100327.1 CDS Amir_2544 NC_013093.1 2867902 2868957 D hypothetical protein 2867902..2868957 Actinosynnema mirum DSM 43827 8326733 YP_003100328.1 CDS Amir_2545 NC_013093.1 2868954 2869808 R hypothetical protein complement(2868954..2869808) Actinosynnema mirum DSM 43827 8326734 YP_003100329.1 CDS Amir_2546 NC_013093.1 2869873 2870685 R hypothetical protein complement(2869873..2870685) Actinosynnema mirum DSM 43827 8326735 YP_003100330.1 CDS Amir_2547 NC_013093.1 2870880 2871998 D KEGG: hypothetical protein; hypothetical protein 2870880..2871998 Actinosynnema mirum DSM 43827 8326736 YP_003100331.1 CDS Amir_2548 NC_013093.1 2872074 2875160 R PFAM: acriflavin resistance protein; KEGG: bcb:BCB4264_A5560 transporter, AcrB/AcrD/AcrF family; acriflavin resistance protein complement(2872074..2875160) Actinosynnema mirum DSM 43827 8326737 YP_003100332.1 CDS Amir_2549 NC_013093.1 2875524 2876480 R KEGG: afw:Anae109_0827 hypothetical protein; hypothetical protein complement(2875524..2876480) Actinosynnema mirum DSM 43827 8326738 YP_003100333.1 CDS Amir_2550 NC_013093.1 2876782 2877396 D KEGG: AGAP007349-PA; hypothetical protein 2876782..2877396 Actinosynnema mirum DSM 43827 8326739 YP_003100334.1 CDS Amir_2551 NC_013093.1 2877509 2878942 D PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_1465 major facilitator transporter; major facilitator superfamily protein 2877509..2878942 Actinosynnema mirum DSM 43827 8326740 YP_003100335.1 CDS Amir_2552 NC_013093.1 2879043 2879540 D PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: scl:sce6060 hypothetical protein; Activator of Hsp90 ATPase 1 family protein 2879043..2879540 Actinosynnema mirum DSM 43827 8326741 YP_003100336.1 CDS Amir_2553 NC_013093.1 2879792 2880706 D PFAM: cytochrome oxidase assembly; KEGG: tgr:Tgr7_3001 cytochrome oxidase assembly; cytochrome oxidase assembly 2879792..2880706 Actinosynnema mirum DSM 43827 8326742 YP_003100337.1 CDS Amir_2554 NC_013093.1 2880725 2881183 D KEGG: sf3a2; splicing factor 3a, subunit 2, 66kDa; hypothetical protein 2880725..2881183 Actinosynnema mirum DSM 43827 8326743 YP_003100338.1 CDS Amir_2555 NC_013093.1 2881596 2883752 D KEGG: met:M446_2712 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; diguanylate cyclase/phosphodiesterase 2881596..2883752 Actinosynnema mirum DSM 43827 8326744 YP_003100339.1 CDS Amir_2556 NC_013093.1 2884677 2885825 R PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: dsh:Dshi_3592 Cna B domain-containing protein; Ricin B lectin complement(2884677..2885825) Actinosynnema mirum DSM 43827 8326745 YP_003100340.1 CDS Amir_2557 NC_013093.1 2886075 2886635 R PFAM: regulatory protein TetR; KEGG: ank:AnaeK_2446 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(2886075..2886635) Actinosynnema mirum DSM 43827 8326746 YP_003100341.1 CDS Amir_2558 NC_013093.1 2886739 2887677 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ank:AnaeK_2445 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 2886739..2887677 Actinosynnema mirum DSM 43827 8326747 YP_003100342.1 CDS Amir_2559 NC_013093.1 2887995 2888852 D KEGG: bpt:Bpet3133 translation initiation factor IF- 2; hypothetical protein 2887995..2888852 Actinosynnema mirum DSM 43827 8326748 YP_003100343.1 CDS Amir_2560 NC_013093.1 2888928 2890898 R PFAM: Ricin B lectin; KEGG: scl:sce0966 hypothetical protein; Ricin B lectin complement(2888928..2890898) Actinosynnema mirum DSM 43827 8326749 YP_003100344.1 CDS Amir_2561 NC_013093.1 2891609 2894212 D KEGG: pap:PSPA7_4431 hypothetical protein; hypothetical protein 2891609..2894212 Actinosynnema mirum DSM 43827 8326750 YP_003100345.1 CDS Amir_2562 NC_013093.1 2894209 2895429 D KEGG: rde:RD1_A0036 hypothetical protein; hypothetical protein 2894209..2895429 Actinosynnema mirum DSM 43827 8326751 YP_003100346.1 CDS Amir_2563 NC_013093.1 2895511 2896290 R PFAM: pectate lyase; KEGG: hypothetical protein; pectate lyase complement(2895511..2896290) Actinosynnema mirum DSM 43827 8326752 YP_003100347.1 CDS Amir_2564 NC_013093.1 2896500 2897438 R PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: atc:AGR_L_1807 hypothetical protein; ornithine cyclodeaminase complement(2896500..2897438) Actinosynnema mirum DSM 43827 8326753 YP_003100348.1 CDS Amir_2565 NC_013093.1 2897414 2898508 R PFAM: alanine racemase domain protein; KEGG: atc:AGR_L_1808 hypothetical protein; alanine racemase domain-containing protein complement(2897414..2898508) Actinosynnema mirum DSM 43827 8326754 YP_003100349.1 CDS Amir_2566 NC_013093.1 2898505 2899167 R PFAM: YheO domain protein; KEGG: pfl:PFL_2666 hypothetical protein; YheO domain-containing protein complement(2898505..2899167) Actinosynnema mirum DSM 43827 8326755 YP_003100350.1 CDS Amir_2567 NC_013093.1 2899280 2900359 D KEGG: bxe:Bxe_A2027 acyl-CoA dehydrogenase- related protein; acyl-CoA dehydrogenase-like protein 2899280..2900359 Actinosynnema mirum DSM 43827 8326756 YP_003100351.1 CDS Amir_2568 NC_013093.1 2900344 2901627 D PFAM: LmbE family protein; methyltransferase type 11; NodS family protein; methyltransferase type 12; KEGG: psb:Psyr_3000 methyltransferase; LmbE family protein 2900344..2901627 Actinosynnema mirum DSM 43827 8326757 YP_003100352.1 CDS Amir_2569 NC_013093.1 2901624 2902307 D PFAM: glycosyl transferase family 2; KEGG: xcb:XC_2588 glycosyl transferase-related protein; family 2 glycosyl transferase 2901624..2902307 Actinosynnema mirum DSM 43827 8326758 YP_003100353.1 CDS Amir_2570 NC_013093.1 2902364 2902942 R PFAM: GCN5-related N-acetyltransferase; KEGG: hypothetical protein; GCN5-like N-acetyltransferase complement(2902364..2902942) Actinosynnema mirum DSM 43827 8326759 YP_003100354.1 CDS Amir_2571 NC_013093.1 2903217 2904017 R PFAM: pectate lyase; KEGG: hypothetical protein; pectate lyase complement(2903217..2904017) Actinosynnema mirum DSM 43827 8326760 YP_003100355.1 CDS Amir_2572 NC_013093.1 2904504 2905340 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mca:MCA1942 sugar ABC transporter, permease protein; ABC transporter inner membrane protein 2904504..2905340 Actinosynnema mirum DSM 43827 8326761 YP_003100356.1 CDS Amir_2573 NC_013093.1 2905348 2906199 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smt:Smal_2681 monosaccharide-transporting ATPase; ABC transporter inner membrane protein 2905348..2906199 Actinosynnema mirum DSM 43827 8326762 YP_003100357.1 CDS Amir_2574 NC_013093.1 2906250 2907599 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH1924 sugar transport system (sugar- binding protein); family 1 extracellular solute-binding protein 2906250..2907599 Actinosynnema mirum DSM 43827 8326763 YP_003100358.1 CDS Amir_2575 NC_013093.1 2907684 2909222 D PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: vei:Veis_3457 alpha-N-arabinofuranosidase; alpha-N-arabinofuranosidase 2907684..2909222 Actinosynnema mirum DSM 43827 8326764 YP_003100359.1 CDS Amir_2576 NC_013093.1 2909215 2910954 D PFAM: glycoside hydrolase family 35; glycoside hydrolase family 42 domain protein; KEGG: glb1l; galactosidase, beta 1-like; beta-galactosidase 2909215..2910954 Actinosynnema mirum DSM 43827 8326765 YP_003100360.1 CDS Amir_2577 NC_013093.1 2911112 2912152 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: scl:sce3081 lactose operon repressor; LacI family transcriptional regulator 2911112..2912152 Actinosynnema mirum DSM 43827 8326766 YP_003100361.1 CDS Amir_2578 NC_013093.1 2912272 2913534 R hypothetical protein complement(2912272..2913534) Actinosynnema mirum DSM 43827 8326767 YP_003100362.1 CDS Amir_2579 NC_013093.1 2913527 2914147 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: dal:Dalk_4824 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit complement(2913527..2914147) Actinosynnema mirum DSM 43827 8326768 YP_003100363.1 CDS Amir_2580 NC_013093.1 2914411 2918286 D KEGG: SL44-1; basic proline-rich protein; hypothetical protein 2914411..2918286 Actinosynnema mirum DSM 43827 8326769 YP_003100364.1 CDS Amir_2581 NC_013093.1 2918303 2919166 D hypothetical protein 2918303..2919166 Actinosynnema mirum DSM 43827 8326770 YP_003100365.1 CDS Amir_2582 NC_013093.1 2919258 2919707 D hypothetical protein 2919258..2919707 Actinosynnema mirum DSM 43827 8326771 YP_003100366.1 CDS Amir_2583 NC_013093.1 2919747 2920181 D hypothetical protein 2919747..2920181 Actinosynnema mirum DSM 43827 8326772 YP_003100367.1 CDS Amir_2584 NC_013093.1 2920691 2920951 D hypothetical protein 2920691..2920951 Actinosynnema mirum DSM 43827 8326773 YP_003100368.1 CDS Amir_2585 NC_013093.1 2921297 2921926 D KEGG: ank:AnaeK_0087 hypothetical protein; hypothetical protein 2921297..2921926 Actinosynnema mirum DSM 43827 8326774 YP_003100369.1 CDS Amir_2586 NC_013093.1 2922003 2923367 R KEGG: XylD; endoxylanase D; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase complement(2922003..2923367) Actinosynnema mirum DSM 43827 8326775 YP_003100370.1 CDS Amir_2587 NC_013093.1 2923630 2925090 D PFAM: propeptide PepSY amd peptidase M4; PepSY- associated TM helix domain protein; KEGG: psb:Psyr_2687 PepSY-associated TM helix; propeptide PepSY amd peptidase M4 2923630..2925090 Actinosynnema mirum DSM 43827 8326776 YP_003100371.1 CDS Amir_2588 NC_013093.1 2925087 2925698 D KEGG: acp:A2cp1_3455 tetratricopeptide TPR_2 repeat protein; hypothetical protein 2925087..2925698 Actinosynnema mirum DSM 43827 8326777 YP_003100372.1 CDS Amir_2589 NC_013093.1 2925905 2926495 D PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: kpe:KPK_3281 tetracycline repressor protein class A from transposon 1721; TetR family transcriptional regulator 2925905..2926495 Actinosynnema mirum DSM 43827 8326778 YP_003100373.1 CDS Amir_2590 NC_013093.1 2926751 2927077 D hypothetical protein 2926751..2927077 Actinosynnema mirum DSM 43827 8326779 YP_003100374.1 CDS Amir_2591 NC_013093.1 2927082 2927324 D PFAM: ATP-dependent Clp protease adaptor protein ClpS; ATP-dependent Clp protease adaptor protein ClpS 2927082..2927324 Actinosynnema mirum DSM 43827 8326780 YP_003100375.1 CDS Amir_2592 NC_013093.1 2927321 2927806 D hypothetical protein 2927321..2927806 Actinosynnema mirum DSM 43827 8326781 YP_003100376.1 CDS Amir_2593 NC_013093.1 2927890 2928405 D PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; KEGG: reu:Reut_A1417 Appr-1-p processing; Appr-1-p processing domain-containing protein 2927890..2928405 Actinosynnema mirum DSM 43827 8326782 YP_003100377.1 CDS Amir_2594 NC_013093.1 2928470 2929108 R PFAM: DSBA oxidoreductase; KEGG: scl:sce1376 DSBA oxidoreductase; DSBA oxidoreductase complement(2928470..2929108) Actinosynnema mirum DSM 43827 8326783 YP_003100378.1 CDS Amir_2595 NC_013093.1 2929099 2929221 R hypothetical protein complement(2929099..2929221) Actinosynnema mirum DSM 43827 8326784 YP_003100379.1 CDS Amir_2596 NC_013093.1 2929460 2931043 D TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bpe:BP2620 membrane efflux protein; EmrB/QacA subfamily drug resistance transporter 2929460..2931043 Actinosynnema mirum DSM 43827 8326785 YP_003100380.1 CDS Amir_2597 NC_013093.1 2931234 2931890 D PFAM: regulatory protein TetR; KEGG: pla:Plav_0388 TetR family transcriptional regulator; TetR family transcriptional regulator 2931234..2931890 Actinosynnema mirum DSM 43827 8326786 YP_003100381.1 CDS Amir_2598 NC_013093.1 2932477 2932887 D hypothetical protein 2932477..2932887 Actinosynnema mirum DSM 43827 8326787 YP_003100382.1 CDS Amir_2599 NC_013093.1 2932884 2933285 D PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sus:Acid_1594 GntR family transcriptional regulator; GntR family transcriptional regulator 2932884..2933285 Actinosynnema mirum DSM 43827 8326788 YP_003100383.1 CDS Amir_2600 NC_013093.1 2933340 2934743 R KEGG: hypothetical protein LOC100018482; hypothetical protein complement(2933340..2934743) Actinosynnema mirum DSM 43827 8326789 YP_003100384.1 CDS Amir_2601 NC_013093.1 2934763 2934903 R hypothetical protein complement(2934763..2934903) Actinosynnema mirum DSM 43827 8326790 YP_003100385.1 CDS Amir_2602 NC_013093.1 2934896 2935165 R PFAM: Sigma-70 region 4 type 2; KEGG: ajs:Ajs_2554 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit complement(2934896..2935165) Actinosynnema mirum DSM 43827 8326791 YP_003100386.1 CDS Amir_2603 NC_013093.1 2935187 2935453 R PFAM: sigma-70 region 2 domain protein; KEGG: scl:sce6054 ECF family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit complement(2935187..2935453) Actinosynnema mirum DSM 43827 8326792 YP_003100387.1 CDS Amir_2605 NC_013093.1 2936321 2937337 R PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: tgr:Tgr7_0733 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(2936321..2937337) Actinosynnema mirum DSM 43827 8326794 YP_003100388.1 CDS Amir_2606 NC_013093.1 2937510 2937896 R TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist complement(2937510..2937896) Actinosynnema mirum DSM 43827 8326795 YP_003100389.1 CDS Amir_2607 NC_013093.1 2938060 2938791 R PFAM: ANTAR domain protein; KEGG: mpo:Mpop_5014 response regulator receiver and ANTAR domain protein; ANTAR domain-containing protein with unknown sensor complement(2938060..2938791) Actinosynnema mirum DSM 43827 8326796 YP_003100390.1 CDS Amir_2608 NC_013093.1 2939083 2939847 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cak:Caul_1958 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(2939083..2939847) Actinosynnema mirum DSM 43827 8326797 YP_003100391.1 CDS Amir_2609 NC_013093.1 2939926 2940540 D PFAM: regulatory protein TetR; KEGG: gdi:GDI0313 TetR family transcriptional regulator; TetR family transcriptional regulator 2939926..2940540 Actinosynnema mirum DSM 43827 8326798 YP_003100392.1 CDS Amir_2610 NC_013093.1 2940611 2941480 R PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: scl:sce0163 hypothetical protein; Extradiol ring-cleavage dioxygenase class III protein subunit B complement(2940611..2941480) Actinosynnema mirum DSM 43827 8326799 YP_003100393.1 CDS Amir_2611 NC_013093.1 2941480 2942319 R PFAM: NmrA family protein; dTDP-4-dehydrorhamnose reductase; KEGG: mxa:MXAN_5100 NmrA family protein; NmrA family protein complement(2941480..2942319) Actinosynnema mirum DSM 43827 8326800 YP_003100394.1 CDS Amir_2612 NC_013093.1 2942367 2942849 R PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bpt:Bpet2994 MarR family transcriptional regulator; MarR family transcriptional regulator complement(2942367..2942849) Actinosynnema mirum DSM 43827 8326801 YP_003100395.1 CDS Amir_2613 NC_013093.1 2942947 2944971 D hypothetical protein 2942947..2944971 Actinosynnema mirum DSM 43827 8326802 YP_003100396.1 CDS Amir_2614 NC_013093.1 2945111 2946313 R PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 complement(2945111..2946313) Actinosynnema mirum DSM 43827 8326803 YP_003100397.1 CDS Amir_2615 NC_013093.1 2946424 2947074 D PFAM: regulatory protein TetR; KEGG: cak:Caul_4437 TetR family transcriptional regulator; TetR family transcriptional regulator 2946424..2947074 Actinosynnema mirum DSM 43827 8326804 YP_003100398.1 CDS Amir_2616 NC_013093.1 2947636 2949258 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mrd:Mrad2831_2095 ABC transporter; ABC transporter 2947636..2949258 Actinosynnema mirum DSM 43827 8326805 YP_003100399.1 CDS Amir_2618 NC_013093.1 2949727 2950524 R KEGG: mxa:MXAN_6120 hypothetical protein; hypothetical protein complement(2949727..2950524) Actinosynnema mirum DSM 43827 8326807 YP_003100400.1 CDS Amir_2619 NC_013093.1 2950632 2950937 D PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: rpd:RPD_3981 helix-turn-helix, type 11; ArsR family transcriptional regulator 2950632..2950937 Actinosynnema mirum DSM 43827 8326808 YP_003100401.1 CDS Amir_2620 NC_013093.1 2950934 2951320 D PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppw:PputW619_2963 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2950934..2951320 Actinosynnema mirum DSM 43827 8326809 YP_003100402.1 CDS Amir_2621 NC_013093.1 2951358 2952320 R PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: pat:Patl_3506 inosine/uridine-preferring nucleoside hydrolase; Inosine/uridine-preferring nucleoside hydrolase complement(2951358..2952320) Actinosynnema mirum DSM 43827 8326810 YP_003100403.1 CDS Amir_2622 NC_013093.1 2952595 2954967 R PFAM: major facilitator superfamily MFS_1; riboflavin kinase; flavin reductase domain protein FMN- binding; KEGG: xfa:XF1765 drug:proton antiporter; major facilitator superfamily protein complement(2952595..2954967) Actinosynnema mirum DSM 43827 8326811 YP_003100404.1 CDS Amir_2623 NC_013093.1 2954964 2956298 R KEGG: mms:mma_3466 xenobiotic compound monooxygenase A subunit; xenobiotic compound monooxygenase A subunit complement(2954964..2956298) Actinosynnema mirum DSM 43827 8326812 YP_003100405.1 CDS Amir_2624 NC_013093.1 2956295 2956975 R PFAM: isochorismatase hydrolase; KEGG: pla:Plav_0992 isochorismatase hydrolase; isochorismatase hydrolase complement(2956295..2956975) Actinosynnema mirum DSM 43827 8326813 YP_003100406.1 CDS Amir_2625 NC_013093.1 2956975 2958036 R PFAM: luciferase-like monooxygenase; KEGG: ccs:CCNA_01227 nitrilotriacetate monooxygenase; luciferase-like monooxygenase complement(2956975..2958036) Actinosynnema mirum DSM 43827 8326814 YP_003100407.1 CDS Amir_2626 NC_013093.1 2958083 2959228 R PFAM: NMT1/THI5 like domain protein; KEGG: oan:Oant_0280 NMT1/THI5 like domain protein; NMT1/THI5 like domain-containing protein complement(2958083..2959228) Actinosynnema mirum DSM 43827 8326815 YP_003100408.1 CDS Amir_2627 NC_013093.1 2959399 2960265 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbr:BB0643 transport system permease protein; ABC transporter inner membrane protein complement(2959399..2960265) Actinosynnema mirum DSM 43827 8326816 YP_003100409.1 CDS Amir_2628 NC_013093.1 2960280 2961107 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pla:Plav_0892 ABC transporter; ABC transporter complement(2960280..2961107) Actinosynnema mirum DSM 43827 8326817 YP_003100410.1 CDS Amir_2629 NC_013093.1 2961293 2961730 R hypothetical protein complement(2961293..2961730) Actinosynnema mirum DSM 43827 8326818 YP_003100411.1 CDS Amir_2630 NC_013093.1 2962075 2962677 R KEGG: bch:Bcen2424_2530 hypothetical protein; hypothetical protein complement(2962075..2962677) Actinosynnema mirum DSM 43827 8326819 YP_003100412.1 CDS Amir_2631 NC_013093.1 2962674 2964263 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rso:RS02380 two-component sensor histidine kinase transcription regulator protein; histidine kinase complement(2962674..2964263) Actinosynnema mirum DSM 43827 8326820 YP_003100413.1 CDS Amir_2632 NC_013093.1 2964260 2964949 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfu:Sfum_2007 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator complement(2964260..2964949) Actinosynnema mirum DSM 43827 8326821 YP_003100414.1 CDS Amir_2633 NC_013093.1 2965420 2966697 D PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: sal:Sala_3102 hypothetical protein; hypothetical protein 2965420..2966697 Actinosynnema mirum DSM 43827 8326822 YP_003100415.1 CDS Amir_2634 NC_013093.1 2966794 2967015 D KEGG: hypothetical protein; hypothetical protein 2966794..2967015 Actinosynnema mirum DSM 43827 8326823 YP_003100416.1 CDS Amir_2635 NC_013093.1 2967074 2968042 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: pla:Plav_2411 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein complement(2967074..2968042) Actinosynnema mirum DSM 43827 8326824 YP_003100417.1 CDS Amir_2636 NC_013093.1 2968561 2969349 D PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: mno:Mnod_4658 molybdopterin dehydrogenase FAD- binding; FAD-binding molybdopterin dehydrogenase 2968561..2969349 Actinosynnema mirum DSM 43827 8326825 YP_003100418.1 CDS Amir_2637 NC_013093.1 2969349 2972042 D PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: azc:AZC_4623 dehydrogenase; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 2969349..2972042 Actinosynnema mirum DSM 43827 8326826 YP_003100419.1 CDS Amir_2638 NC_013093.1 2972032 2973465 R PFAM: FAD dependent oxidoreductase; KEGG: scl:sce3282 monooxygenase flavin-binding family protein; FAD dependent oxidoreductase complement(2972032..2973465) Actinosynnema mirum DSM 43827 8326827 YP_003100420.1 CDS Amir_2639 NC_013093.1 2973644 2974234 D PFAM: regulatory protein TetR; KEGG: lch:Lcho_1914 TetR family transcriptional regulator; TetR family transcriptional regulator 2973644..2974234 Actinosynnema mirum DSM 43827 8326828 YP_003100421.1 CDS Amir_2640 NC_013093.1 2974574 2975272 R hypothetical protein complement(2974574..2975272) Actinosynnema mirum DSM 43827 8326829 YP_003100422.1 CDS Amir_2641 NC_013093.1 2975269 2975823 R PFAM: conserved hypothetical protein; KEGG: lch:Lcho_0031 hypothetical protein; hypothetical protein complement(2975269..2975823) Actinosynnema mirum DSM 43827 8326830 YP_003100423.1 CDS Amir_2642 NC_013093.1 2975820 2976317 R hypothetical protein complement(2975820..2976317) Actinosynnema mirum DSM 43827 8326831 YP_003100424.1 CDS Amir_2643 NC_013093.1 2976381 2977709 R KEGG: hypothetical protein; hypothetical protein complement(2976381..2977709) Actinosynnema mirum DSM 43827 8326832 YP_003100425.1 CDS Amir_2644 NC_013093.1 2977706 2978206 R KEGG: hypothetical protein; hypothetical protein complement(2977706..2978206) Actinosynnema mirum DSM 43827 8326833 YP_003100426.1 CDS Amir_2645 NC_013093.1 2978443 2979207 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pol:Bpro_0095 transcriptional regulator NanR; GntR family transcriptional regulator complement(2978443..2979207) Actinosynnema mirum DSM 43827 8326834 YP_003100427.1 CDS Amir_2646 NC_013093.1 2979418 2980779 D PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0865 transport protein; major facilitator superfamily protein 2979418..2980779 Actinosynnema mirum DSM 43827 8326835 YP_003100428.1 CDS Amir_2647 NC_013093.1 2980776 2982479 D in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone; dihydroxyacetone kinase 2980776..2982479 Actinosynnema mirum DSM 43827 8326836 YP_003100429.1 CDS Amir_2648 NC_013093.1 2982534 2983016 D TIGRFAM: ribose 5-phosphate isomerase; sugar- phosphate isomerase, RpiB/LacA/LacB family; PFAM: ribose/galactose isomerase; KEGG: similar to ribose 5-phosphate isomerase; K01808 ribose 5-phosphate isomerase B; ribose 5-phosphate isomerase 2982534..2983016 Actinosynnema mirum DSM 43827 8326837 YP_003100430.1 CDS Amir_2649 NC_013093.1 2983016 2983789 D PFAM: triosephosphate isomerase; KEGG: eca:ECA0867 triosephosphate isomerase; triose-phosphate isomerase 2983016..2983789 Actinosynnema mirum DSM 43827 8326838 YP_003100431.1 CDS Amir_2650 NC_013093.1 2983786 2984586 D PFAM: xylose isomerase; KEGG: eca:ECA0868 hypothetical protein; xylose isomerase 2983786..2984586 Actinosynnema mirum DSM 43827 8326839 YP_003100432.1 CDS Amir_2651 NC_013093.1 2984583 2985437 D PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Acetohydroxy acid isomeroreductase catalytic domain protein; KEGG: eca:ECA0869 hypothetical protein; NADP oxidoreductase coenzyme F420-dependent 2984583..2985437 Actinosynnema mirum DSM 43827 8326840 YP_003100433.1 CDS Amir_2652 NC_013093.1 2986179 2986871 D TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: scl:sce0560 hypothetical protein; CRISPR-associated protein, Cse3 family 2986179..2986871 Actinosynnema mirum DSM 43827 8326841 YP_003100434.1 CDS Amir_2653 NC_013093.1 2988003 2988200 R hypothetical protein complement(2988003..2988200) Actinosynnema mirum DSM 43827 8326842 YP_003100435.1 CDS Amir_2654 NC_013093.1 2988393 2988938 D KEGG: gbe:GbCGDNIH1_0912 phosphate transport system permease protein PstA; hypothetical protein 2988393..2988938 Actinosynnema mirum DSM 43827 8326843 YP_003100436.1 CDS Amir_2655 NC_013093.1 2988961 2989506 D KEGG: scl:sce2943 phosphate ABC transporter, ATP- binding protein PstB; phosphate ABC transporter ATP-binding protein PstB 2988961..2989506 Actinosynnema mirum DSM 43827 8326844 YP_003100437.1 CDS Amir_2656 NC_013093.1 2989650 2990159 R KEGG: yen:YE4124 isochorismatase family hydrolase; hypothetical protein complement(2989650..2990159) Actinosynnema mirum DSM 43827 8326845 YP_003100438.1 CDS Amir_2657 NC_013093.1 2990251 2990916 D hypothetical protein 2990251..2990916 Actinosynnema mirum DSM 43827 8326846 YP_003100439.1 CDS Amir_2658 NC_013093.1 2991381 2992367 D PFAM: FAD dependent oxidoreductase; KEGG: azo:azo0209 sarcosine oxidase, beta subunit; FAD dependent oxidoreductase 2991381..2992367 Actinosynnema mirum DSM 43827 8326847 YP_003100440.1 CDS Amir_2659 NC_013093.1 2992840 2993079 D KEGG: bha:BH1846 acyl-carrier protein; acyl-carrier protein 2992840..2993079 Actinosynnema mirum DSM 43827 8326848 YP_003100441.1 CDS Amir_2660 NC_013093.1 2993188 2994534 D KEGG: bmv:BMASAVP1_A1623 L-ornithine 5- monooxygenase; L-lysine 6-monooxygenase (NADPH) 2993188..2994534 Actinosynnema mirum DSM 43827 8326849 YP_003100442.1 CDS Amir_2661 NC_013093.1 2994572 2994940 D PFAM: cupin; KEGG: psp:PSPPH_2411 hypothetical protein; cupin 2994572..2994940 Actinosynnema mirum DSM 43827 8326850 YP_003100443.1 CDS Amir_2662 NC_013093.1 2994937 2996565 D PFAM: tRNA synthetase class I (M); KEGG: pen:PSEEN0982 methionine--tRNA ligase; methionine--tRNA ligase 2994937..2996565 Actinosynnema mirum DSM 43827 8326851 YP_003100444.1 CDS Amir_2663 NC_013093.1 2996575 2997816 D PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylglycinamide synthetase; KEGG: plu:plu0116 hypothetical protein; ATP-dependent carboxylate-amine ligase domain-containing protein 2996575..2997816 Actinosynnema mirum DSM 43827 8326852 YP_003100445.1 CDS Amir_2664 NC_013093.1 2997919 2998740 D PFAM: amidinotransferase; KEGG: aeh:Mlg_0130 amidinotransferase; amidinotransferase 2997919..2998740 Actinosynnema mirum DSM 43827 8326853 YP_003100446.1 CDS Amir_2665 NC_013093.1 2998737 2999099 D KEGG: gbm:Gbem_0509 hypothetical protein; hypothetical protein 2998737..2999099 Actinosynnema mirum DSM 43827 8326854 YP_003100447.1 CDS Amir_2666 NC_013093.1 2999243 3001096 D PFAM: extracellular solute-binding protein family 5; KEGG: acr:Acry_1185 extracellular solute-binding protein; family 5 extracellular solute-binding protein 2999243..3001096 Actinosynnema mirum DSM 43827 8326855 YP_003100448.1 CDS Amir_2667 NC_013093.1 3001093 3002400 D PFAM: sodium/hydrogen exchanger; KEGG: mno:Mnod_3112 sodium/hydrogen exchanger; sodium/hydrogen exchanger 3001093..3002400 Actinosynnema mirum DSM 43827 8326856 YP_003100449.1 CDS Amir_2668 NC_013093.1 3002520 3003767 D PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: plu:plu0116 hypothetical protein; phosphoribosylglycinamide synthetase 3002520..3003767 Actinosynnema mirum DSM 43827 8326857 YP_003100450.1 CDS Amir_2669 NC_013093.1 3003888 3005195 D PFAM: major facilitator superfamily MFS_1; KEGG: ank:AnaeK_4388 major facilitator superfamily MFS_1; major facilitator superfamily protein 3003888..3005195 Actinosynnema mirum DSM 43827 8326858 YP_003100451.1 CDS Amir_2670 NC_013093.1 3005322 3005822 D hypothetical protein 3005322..3005822 Actinosynnema mirum DSM 43827 8326859 YP_003100452.1 CDS Amir_2671 NC_013093.1 3006523 3008538 D PFAM: O-methyltransferase; KEGG: mxa:MXAN_2296 O-methyltransferase family protein; O-methyltransferase 3006523..3008538 Actinosynnema mirum DSM 43827 8326860 YP_003100453.1 CDS Amir_2672 NC_013093.1 3008596 3009199 R KEGG: ade:Adeh_0244 LigA; LigA complement(join(3008596..3009096,3009098..3009199)) Actinosynnema mirum DSM 43827 8326861 YP_003100454.1 CDS Amir_2673 NC_013093.1 3009401 3012139 D KEGG: hypothetical protein; hypothetical protein 3009401..3012139 Actinosynnema mirum DSM 43827 8326862 YP_003100455.1 CDS Amir_2674 NC_013093.1 3012438 3013211 D KEGG: hch:HCH_01940 phytoene dehydrogenase and related protein; hypothetical protein 3012438..3013211 Actinosynnema mirum DSM 43827 8326863 YP_003100456.1 CDS Amir_2675 NC_013093.1 3013345 3015956 D PFAM: hypothetical protein; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; hypothetical protein join(3013345..3015780,3015780..3015956) Actinosynnema mirum DSM 43827 8326864 YP_003100457.1 CDS Amir_2676 NC_013093.1 3016403 3017134 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bca:BCE_2589 ATP-binding transport protein NatA; ABC transporter 3016403..3017134 Actinosynnema mirum DSM 43827 8326865 YP_003100458.1 CDS Amir_2677 NC_013093.1 3017170 3017430 D hypothetical protein 3017170..3017430 Actinosynnema mirum DSM 43827 8326866 YP_003100459.1 CDS Amir_2678 NC_013093.1 3017571 3018395 R PFAM: Thioesterase; KEGG: bpd:BURPS668_A0873 pyochelin biosynthetic protein PchC; oleoyl-(acyl-carrier-protein) hydrolase complement(3017571..3018395) Actinosynnema mirum DSM 43827 8326867 YP_003100460.1 CDS Amir_2679 NC_013093.1 3018623 3019255 R PFAM: regulatory protein TetR; KEGG: tmz:Tmz1t_0804 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(3018623..3019255) Actinosynnema mirum DSM 43827 8326868 YP_003100461.1 CDS Amir_2680 NC_013093.1 3019338 3021143 D PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_1369 major facilitator superfamily MFS_1; major facilitator superfamily protein 3019338..3021143 Actinosynnema mirum DSM 43827 8326869 YP_003100462.1 CDS Amir_2681 NC_013093.1 3021545 3026995 D PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; KR domain protein; acyl transferase; erythronolide synthase docking; phosphopantetheine- binding; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA0602 type I polyketide synthase; short-chain dehydrogenase/reductase SDR 3021545..3026995 Actinosynnema mirum DSM 43827 8326870 YP_003100463.1 CDS Amir_2682 NC_013093.1 3027042 3036320 D PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; acyl transferase; KR domain protein; erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; short-chain dehydrogenase/reductase SDR 3027042..3036320 Actinosynnema mirum DSM 43827 8326871 YP_003100464.1 CDS Amir_2683 NC_013093.1 3036332 3041137 D PFAM: acyl transferase; beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 3036332..3041137 Actinosynnema mirum DSM 43827 8326872 YP_003100465.1 CDS Amir_2684 NC_013093.1 3041176 3057378 D PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; acyl transferase; KR domain protein; erythronolide synthase docking; Thioesterase; NAD- dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: met:M446_0170 beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR 3041176..3057378 Actinosynnema mirum DSM 43827 8326873 YP_003100466.1 CDS Amir_2685 NC_013093.1 3057462 3058352 D TIGRFAM: proline-specific peptidase; PFAM: alpha/beta hydrolase fold; KEGG: rru:Rru_A2180 peptidase S33, tricorn interacting factor 1; proline-specific peptidase 3057462..3058352 Actinosynnema mirum DSM 43827 8326874 YP_003100467.1 CDS Amir_2686 NC_013093.1 3058366 3058851 R hypothetical protein complement(3058366..3058851) Actinosynnema mirum DSM 43827 8326875 YP_003100468.1 CDS Amir_2687 NC_013093.1 3059008 3059256 R KEGG: mrd:Mrad2831_0184 phosphopantetheine-binding; phosphopantetheine-binding complement(3059008..3059256) Actinosynnema mirum DSM 43827 8326876 YP_003100469.1 CDS Amir_2688 NC_013093.1 3059475 3061064 D PFAM: AMP-dependent synthetase and ligase; KEGG: gbm:Gbem_0542 amino acid adenylation domain protein; AMP-dependent synthetase and ligase 3059475..3061064 Actinosynnema mirum DSM 43827 8326877 YP_003100470.1 CDS Amir_2689 NC_013093.1 3061179 3062702 R PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_0131 amino acid adenylation domain- containing protein; AMP-dependent synthetase and ligase complement(3061179..3062702) Actinosynnema mirum DSM 43827 8326878 YP_003100471.1 CDS Amir_2690 NC_013093.1 3062743 3063669 R KEGG: plu:plu2834 acyl carrier protein S- malonyltransferase; (acyl-carrier-protein)S-malonyltransferase-like protein complement(3062743..3063669) Actinosynnema mirum DSM 43827 8326879 YP_003100472.1 CDS Amir_2691 NC_013093.1 3063696 3064955 R PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase; class I and II aminotransferase complement(3063696..3064955) Actinosynnema mirum DSM 43827 8326880 YP_003100473.1 CDS Amir_2692 NC_013093.1 3065051 3066403 R KEGG: mxa:MXAN_6263 hypothetical protein; L-lysine 2,3-aminomutase complement(3065051..3066403) Actinosynnema mirum DSM 43827 8326881 YP_003100474.1 CDS Amir_2693 NC_013093.1 3066961 3068148 D PFAM: cytochrome P450; KEGG: bca:BCE_2696 cytochrome P450; cytochrome P450 3066961..3068148 Actinosynnema mirum DSM 43827 8326882 YP_003100475.1 CDS Amir_2694 NC_013093.1 3068145 3068387 D KEGG: cak:Caul_1918 hypothetical protein; hypothetical protein 3068145..3068387 Actinosynnema mirum DSM 43827 8326883 YP_003100476.1 CDS Amir_2695 NC_013093.1 3068486 3089818 D PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; Male sterility domain; acyl transferase; KR domain protein; phosphopantetheine- binding; NAD-dependent epimerase/dehydratase; KEGG: met:M446_0170 beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR 3068486..3089818 Actinosynnema mirum DSM 43827 8326884 YP_003100477.1 CDS Amir_2696 NC_013093.1 3090196 3092991 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: reh:H16_A1278 ATP-dependent transcriptional regulator containing adenylate cyclase related domains; LuxR family transcriptional regulator 3090196..3092991 Actinosynnema mirum DSM 43827 8326885 YP_003100478.1 CDS Amir_2697 NC_013093.1 3093198 3094037 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: glo:Glov_3629 ABC transporter; ABC transporter 3093198..3094037 Actinosynnema mirum DSM 43827 8326886 YP_003100479.1 CDS Amir_2698 NC_013093.1 3094037 3096604 D PFAM: protein of unknown function DUF214; KEGG: gme:Gmet_1517 hypothetical protein; hypothetical protein 3094037..3096604 Actinosynnema mirum DSM 43827 8326887 YP_003100480.1 CDS Amir_2699 NC_013093.1 3097146 3097826 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: psb:Psyr_1940 LuxR response regulator receiver; LuxR family transcriptional regulator complement(3097146..3097826) Actinosynnema mirum DSM 43827 8326888 YP_003100481.1 CDS Amir_2700 NC_013093.1 3097790 3099079 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: cps:CPS_1261 sensor histidine kinase; histidine kinase complement(3097790..3099079) Actinosynnema mirum DSM 43827 8326889 YP_003100482.1 CDS Amir_2701 NC_013093.1 3099293 3100354 D hypothetical protein 3099293..3100354 Actinosynnema mirum DSM 43827 8326890 YP_003100483.1 CDS Amir_2702 NC_013093.1 3100521 3101567 D KEGG: hypothetical protein; hypothetical protein 3100521..3101567 Actinosynnema mirum DSM 43827 8326891 YP_003100484.1 CDS Amir_2703 NC_013093.1 3101661 3103421 D PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; Cna B domain-containing protein 3101661..3103421 Actinosynnema mirum DSM 43827 8326892 YP_003100485.1 CDS Amir_2704 NC_013093.1 3103431 3103922 R PFAM: O-methyltransferase; KEGG: mlo:mlr0279 O-methyltransferase; O-methyltransferase complement(3103431..3103922) Actinosynnema mirum DSM 43827 8326893 YP_003100486.1 CDS Amir_2705 NC_013093.1 3103926 3105230 R KEGG: afw:Anae109_2424 DNA mismatch repair protein MutS domain-containing protein; hypothetical protein complement(3103926..3105230) Actinosynnema mirum DSM 43827 8326894 YP_003100487.1 CDS Amir_2706 NC_013093.1 3105498 3106568 D PFAM: periplasmic binding protein; KEGG: rle:RL3052 cationic solute-binding component of ABC transporter; periplasmic binding protein 3105498..3106568 Actinosynnema mirum DSM 43827 8326895 YP_003100488.1 CDS Amir_2707 NC_013093.1 3106565 3107587 D PFAM: transport system permease protein; ABC transporter; KEGG: rec:RHECIAT_PC0000463 iron ABC transporter, permease protein; transport system permease 3106565..3107587 Actinosynnema mirum DSM 43827 8326896 YP_003100489.1 CDS Amir_2708 NC_013093.1 3107584 3108357 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mpo:Mpop_4222 ABC transporter; ABC transporter 3107584..3108357 Actinosynnema mirum DSM 43827 8326897 YP_003100490.1 CDS Amir_2709 NC_013093.1 3108506 3109084 R PFAM: regulatory protein TetR; KEGG: bcr:BCAH187_A5151 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(3108506..3109084) Actinosynnema mirum DSM 43827 8326898 YP_003100491.1 CDS Amir_2710 NC_013093.1 3109179 3109892 D PFAM: beta-lactamase domain protein; KEGG: Zn-dependent hydrolases, including glyoxylases; beta-lactamase domain-containing protein 3109179..3109892 Actinosynnema mirum DSM 43827 8326899 YP_003100492.1 CDS Amir_2711 NC_013093.1 3110003 3110284 D KEGG: sal:Sala_0018 hypothetical protein; hypothetical protein 3110003..3110284 Actinosynnema mirum DSM 43827 8326900 YP_003100493.1 CDS Amir_2712 NC_013093.1 3110281 3110814 R KEGG: jan:Jann_1769 mucin-associated surface protein; mucin-associated surface protein complement(3110281..3110814) Actinosynnema mirum DSM 43827 8326901 YP_003100494.1 CDS Amir_2713 NC_013093.1 3110811 3113327 R PFAM: NB-ARC domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; NB-ARC domain-containing protein complement(3110811..3113327) Actinosynnema mirum DSM 43827 8326902 YP_003100495.1 CDS Amir_2714 NC_013093.1 3113324 3113875 R PFAM: regulatory protein TetR; KEGG: mxa:MXAN_2145 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(3113324..3113875) Actinosynnema mirum DSM 43827 8326903 YP_003100496.1 CDS Amir_2715 NC_013093.1 3113968 3114873 D PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4431 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin; luciferase-like monooxygenase 3113968..3114873 Actinosynnema mirum DSM 43827 8326904 YP_003100497.1 CDS Amir_2716 NC_013093.1 3114940 3117765 R PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; LuxR family transcriptional regulator complement(3114940..3117765) Actinosynnema mirum DSM 43827 8326905 YP_003100498.1 CDS Amir_2717 NC_013093.1 3118394 3119455 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3118394..3119455) Actinosynnema mirum DSM 43827 8326906 YP_003100499.1 CDS Amir_2718 NC_013093.1 3119448 3120851 R TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: gdj:Gdia_2404 drug resistance transporter, EmrB/QacA subfamily; EmrB/QacA subfamily drug resistance transporter complement(3119448..3120851) Actinosynnema mirum DSM 43827 8326907 YP_003100500.1 CDS Amir_2719 NC_013093.1 3120848 3131080 R TIGRFAM: amino acid adenylation domain protein; non- ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: pap:PSPA7_2858 peptide synthase; amino acid adenylation domain-containing protein complement(3120848..3131080) Actinosynnema mirum DSM 43827 8326908 YP_003100501.1 CDS Amir_2720 NC_013093.1 3131153 3131938 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: dac:Daci_3149 ABC transporter; ABC transporter complement(3131153..3131938) Actinosynnema mirum DSM 43827 8326909 YP_003100502.1 CDS Amir_2721 NC_013093.1 3131935 3132951 R PFAM: transport system permease protein; KEGG: yen:YE3620 iron-enterobactin transporter permease; transport system permease complement(3131935..3132951) Actinosynnema mirum DSM 43827 8326910 YP_003100503.1 CDS Amir_2722 NC_013093.1 3132948 3133946 R PFAM: transport system permease protein; KEGG: cvi:CV_2236 iron-enterobactin transporter membrane protein; transport system permease complement(3132948..3133946) Actinosynnema mirum DSM 43827 8326911 YP_003100504.1 CDS Amir_2723 NC_013093.1 3133943 3134965 R PFAM: periplasmic binding protein; KEGG: bsu:BSU39610 hypothetical protein; periplasmic binding protein complement(3133943..3134965) Actinosynnema mirum DSM 43827 8326912 YP_003100505.1 CDS Amir_2724 NC_013093.1 3135012 3135947 R PFAM: siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: cti:RALTA_B1102 siderophore-interacting protein; siderophore-interacting protein complement(3135012..3135947) Actinosynnema mirum DSM 43827 8326913 YP_003100506.1 CDS Amir_2726 NC_013093.1 3136848 3138524 R PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce3880 (2,3-dihydroxybenzoyl)adenylate synthase; AMP-dependent synthetase and ligase complement(3136848..3138524) Actinosynnema mirum DSM 43827 8326915 YP_003100507.1 CDS Amir_2727 NC_013093.1 3138521 3140032 R TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: mxa:MXAN_3646 isochorismate synthase DhbC; isochorismate synthase complement(3138521..3140032) Actinosynnema mirum DSM 43827 8326916 YP_003100508.1 CDS Amir_2728 NC_013093.1 3140270 3141040 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bcy:Bcer98_1754 2,3-dihydroxybenzoate-2,3- dehydrogenase; short-chain dehydrogenase/reductase SDR complement(3140270..3141040) Actinosynnema mirum DSM 43827 8326917 YP_003100509.1 CDS Amir_2729 NC_013093.1 3141299 3142846 R PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: hypothetical protein; TAP domain-containing protein complement(3141299..3142846) Actinosynnema mirum DSM 43827 8326918 YP_003100510.1 CDS Amir_2730 NC_013093.1 3143249 3144301 D PFAM: transport system permease protein; KEGG: dac:Daci_3791 transport system permease protein; transport system permease 3143249..3144301 Actinosynnema mirum DSM 43827 8326919 YP_003100511.1 CDS Amir_2731 NC_013093.1 3144301 3145068 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bte:BTH_I1413 iron compound ABC transporter, ATP-binding protein; ABC transporter 3144301..3145068 Actinosynnema mirum DSM 43827 8326920 YP_003100512.1 CDS Amir_2732 NC_013093.1 3145138 3146154 D PFAM: periplasmic binding protein; KEGG: bpd:BURPS668_3152 iron chelate uptake ABC transporter, periplasmic solute-binding protein; periplasmic binding protein 3145138..3146154 Actinosynnema mirum DSM 43827 8326921 YP_003100513.1 CDS Amir_2733 NC_013093.1 3146360 3146572 R SMART: helix-turn-helix domain protein; KEGG: bcr:BCAH187_A3038 DNA-binding protein; XRE family transcriptional regulator complement(3146360..3146572) Actinosynnema mirum DSM 43827 8326922 YP_003100514.1 CDS Amir_2734 NC_013093.1 3146574 3147053 R hypothetical protein complement(3146574..3147053) Actinosynnema mirum DSM 43827 8326923 YP_003100515.1 CDS Amir_2735 NC_013093.1 3147165 3147662 R KEGG: bpl:BURPS1106A_1193 DNA translocase FtsK; hypothetical protein complement(3147165..3147662) Actinosynnema mirum DSM 43827 8326924 YP_003100516.1 CDS Amir_2736 NC_013093.1 3147876 3149168 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3147876..3149168 Actinosynnema mirum DSM 43827 8326925 YP_003100517.1 CDS Amir_2737 NC_013093.1 3149165 3149848 D PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 3149165..3149848 Actinosynnema mirum DSM 43827 8326926 YP_003100518.1 CDS Amir_2739 NC_013093.1 3153038 3154318 D KEGG: azc:AZC_3061 enolase; TIGRFAM: enolase; PFAM: enolase; enolase 3153038..3154318 Actinosynnema mirum DSM 43827 8326928 YP_003100519.1 CDS Amir_2740 NC_013093.1 3154305 3154508 R hypothetical protein complement(3154305..3154508) Actinosynnema mirum DSM 43827 8326929 YP_003100520.1 CDS Amir_2741 NC_013093.1 3154505 3155335 R hypothetical protein complement(3154505..3155335) Actinosynnema mirum DSM 43827 8326930 YP_003100521.1 CDS Amir_2742 NC_013093.1 3155761 3156639 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bsu:BSU09890 hypothetical protein; ABC transporter 3155761..3156639 Actinosynnema mirum DSM 43827 8326931 YP_003100522.1 CDS Amir_2743 NC_013093.1 3156639 3157721 D KEGG: bha:BH1167 hypothetical protein; sodium ABC transporter permease 3156639..3157721 Actinosynnema mirum DSM 43827 8326932 YP_003100523.1 CDS Amir_2744 NC_013093.1 3157897 3159756 D KEGG: hypothetical protein; hypothetical protein 3157897..3159756 Actinosynnema mirum DSM 43827 8326933 YP_003100524.1 CDS Amir_2745 NC_013093.1 3159898 3161466 R PFAM: chemotaxis sensory transducer; GAF domain protein; SMART: chemotaxis sensory transducer; GAF domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer with GAF sensor complement(3159898..3161466) Actinosynnema mirum DSM 43827 8326934 YP_003100525.1 CDS Amir_2746 NC_013093.1 3161696 3162205 D PFAM: GAF domain protein; KEGG: tmz:Tmz1t_1845 multi-sensor hybrid histidine kinase; GAF sensor protein 3161696..3162205 Actinosynnema mirum DSM 43827 8326935 YP_003100526.1 CDS Amir_2747 NC_013093.1 3162460 3163110 D PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: gbm:Gbem_1372 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 3162460..3163110 Actinosynnema mirum DSM 43827 8326936 YP_003100527.1 CDS Amir_2748 NC_013093.1 3163267 3163428 D hypothetical protein 3163267..3163428 Actinosynnema mirum DSM 43827 8326937 YP_003100528.1 CDS Amir_2749 NC_013093.1 3163684 3163986 D hypothetical protein 3163684..3163986 Actinosynnema mirum DSM 43827 8326938 YP_003100529.1 CDS Amir_2750 NC_013093.1 3164541 3171884 D KEGG: bcb:BCB4264_A3445 wall-associated protein; TIGRFAM: YD repeat protein; PFAM: PA14 domain protein; YD repeat-containing protein; SMART: PA14 domain protein; LamG domain protein jellyroll fold domain protein; YD repeat-containing protein 3164541..3171884 Actinosynnema mirum DSM 43827 8326939 YP_003100530.1 CDS Amir_2751 NC_013093.1 3171962 3172429 D hypothetical protein 3171962..3172429 Actinosynnema mirum DSM 43827 8326940 YP_003100531.1 CDS Amir_2752 NC_013093.1 3172442 3172726 R hypothetical protein complement(3172442..3172726) Actinosynnema mirum DSM 43827 8326941 YP_003100532.1 CDS Amir_2753 NC_013093.1 3172827 3173732 R PFAM: sugar isomerase (SIS); KEGG: rso:RSc1377 hypothetical protein; RpiR family transcriptional regulator complement(3172827..3173732) Actinosynnema mirum DSM 43827 8326942 YP_003100533.1 CDS Amir_2754 NC_013093.1 3173871 3175268 D PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: bpy:Bphyt_2088 major facilitator superfamily MFS_1; major facilitator superfamily protein 3173871..3175268 Actinosynnema mirum DSM 43827 8326943 YP_003100534.1 CDS Amir_2755 NC_013093.1 3175265 3175699 D KEGG: vei:Veis_0546 GAF sensor protein; GAF sensor protein 3175265..3175699 Actinosynnema mirum DSM 43827 8326944 YP_003100535.1 CDS Amir_2756 NC_013093.1 3175696 3176907 D PFAM: amidohydrolase; Amidohydrolase 3; KEGG: rru:Rru_A3412 amidohydrolase; amidohydrolase 3175696..3176907 Actinosynnema mirum DSM 43827 8326945 YP_003100536.1 CDS Amir_2757 NC_013093.1 3176968 3177612 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; response regulator receiver; KEGG: bxe:Bxe_A1815 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator complement(3176968..3177612) Actinosynnema mirum DSM 43827 8326946 YP_003100537.1 CDS Amir_2758 NC_013093.1 3177600 3178769 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: mch:Mchl_4713 histidine kinase; histidine kinase complement(3177600..3178769) Actinosynnema mirum DSM 43827 8326947 YP_003100538.1 CDS Amir_2759 NC_013093.1 3178855 3179625 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pla:Plav_1100 ABC transporter; ABC transporter 3178855..3179625 Actinosynnema mirum DSM 43827 8326948 YP_003100539.1 CDS Amir_2760 NC_013093.1 3179625 3182093 D PFAM: protein of unknown function DUF214; KEGG: mxa:MXAN_6766 ABC transporter, permease protein; hypothetical protein 3179625..3182093 Actinosynnema mirum DSM 43827 8326949 YP_003100540.1 CDS Amir_2761 NC_013093.1 3182217 3182645 D PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 3182217..3182645 Actinosynnema mirum DSM 43827 8326950 YP_003100541.1 CDS Amir_2762 NC_013093.1 3183189 3183293 D hypothetical protein 3183189..3183293 Actinosynnema mirum DSM 43827 8326951 YP_003100542.1 CDS Amir_2763 NC_013093.1 3183375 3184583 D KEGG: sdn:Sden_2265 hypothetical protein; hypothetical protein 3183375..3184583 Actinosynnema mirum DSM 43827 8326952 YP_003100543.1 CDS Amir_2764 NC_013093.1 3184580 3186631 D PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: sdn:Sden_2266 hypothetical protein; hypothetical protein 3184580..3186631 Actinosynnema mirum DSM 43827 8326953 YP_003100544.1 CDS Amir_2765 NC_013093.1 3187367 3188599 D PFAM: ROK family protein; KEGG: mxa:MXAN_6549 transcriptional regulator, ROK family; ROK family protein 3187367..3188599 Actinosynnema mirum DSM 43827 8326954 YP_003100545.1 CDS Amir_2766 NC_013093.1 3188784 3190451 D hypothetical protein 3188784..3190451 Actinosynnema mirum DSM 43827 8326955 YP_003100546.1 CDS Amir_2767 NC_013093.1 3190466 3192613 R KEGG: scl:sce5225 protein kinase; hypothetical protein complement(3190466..3192613) Actinosynnema mirum DSM 43827 8326956 YP_003100547.1 CDS Amir_2768 NC_013093.1 3192907 3193557 R KEGG: hypothetical protein; hypothetical protein complement(3192907..3193557) Actinosynnema mirum DSM 43827 8326957 YP_003100548.1 CDS Amir_2769 NC_013093.1 3193712 3195931 R TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: mxa:MXAN_3422 copper-translocating P-type ATPase; heavy metal translocating P-type ATPase complement(3193712..3195931) Actinosynnema mirum DSM 43827 8326958 YP_003100549.1 CDS Amir_2770 NC_013093.1 3195993 3197891 R PFAM: copper resistance D domain protein; KEGG: csa:Csal_0081 hypothetical protein; copper resistance D domain-containing protein complement(3195993..3197891) Actinosynnema mirum DSM 43827 8326959 YP_003100550.1 CDS Amir_2771 NC_013093.1 3198006 3198737 D PFAM: DSBA oxidoreductase; KEGG: mxa:MXAN_3206 DsbA-like thioredoxin domain protein; DSBA oxidoreductase 3198006..3198737 Actinosynnema mirum DSM 43827 8326960 YP_003100551.1 CDS Amir_2772 NC_013093.1 3198734 3199279 D PFAM: vitamin K epoxide reductase; SMART: vitamin K epoxide reductase; KEGG: scl:sce9005 hypothetical protein; vitamin K epoxide reductase 3198734..3199279 Actinosynnema mirum DSM 43827 8326961 YP_003100552.1 CDS Amir_2773 NC_013093.1 3199384 3199962 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: bid:Bind_3241 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit complement(3199384..3199962) Actinosynnema mirum DSM 43827 8326962 YP_003100553.1 CDS Amir_2774 NC_013093.1 3200007 3200735 D KEGG: rso:RS02209 transmembrane protein; integral membrane protein 3200007..3200735 Actinosynnema mirum DSM 43827 8326963 YP_003100554.1 CDS Amir_2775 NC_013093.1 3200780 3201331 D PFAM: GCN5-related N-acetyltransferase; KEGG: bcm:Bcenmc03_1936 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 3200780..3201331 Actinosynnema mirum DSM 43827 8326964 YP_003100555.1 CDS Amir_2776 NC_013093.1 3201351 3201971 R PFAM: regulatory protein TetR; KEGG: bha:BH2103 hypothetical protein; TetR family transcriptional regulator complement(3201351..3201971) Actinosynnema mirum DSM 43827 8326965 YP_003100556.1 CDS Amir_2777 NC_013093.1 3202011 3203837 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: bcb:BCB4264_A1961 ABC transporter, permease/ATP-binding protein; ABC transporter 3202011..3203837 Actinosynnema mirum DSM 43827 8326966 YP_003100557.1 CDS Amir_2778 NC_013093.1 3203971 3204924 D PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4431 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin; luciferase-like monooxygenase 3203971..3204924 Actinosynnema mirum DSM 43827 8326967 YP_003100558.1 CDS Amir_2779 NC_013093.1 3204921 3205478 D PFAM: regulatory protein TetR; KEGG: mrd:Mrad2831_1768 TetR family transcriptional regulator; TetR family transcriptional regulator 3204921..3205478 Actinosynnema mirum DSM 43827 8326968 YP_003100559.1 CDS Amir_2780 NC_013093.1 3205511 3206698 D PFAM: major facilitator superfamily MFS_1; KEGG: kpn:KPN_00876 DeoR-type transcriptional regulator; major facilitator superfamily protein 3205511..3206698 Actinosynnema mirum DSM 43827 8326969 YP_003100560.1 CDS Amir_2781 NC_013093.1 3207073 3209118 D PFAM: glycoside hydrolase family 5; protein of unknown function DUF291; cellulose-binding family II; SMART: cellulose-binding family II; KEGG: bha:BH0603 endo-beta-1,4-glucanase (celulase B); glycoside hydrolase family protein 3207073..3209118 Actinosynnema mirum DSM 43827 8326970 YP_003100561.1 CDS Amir_2782 NC_013093.1 3209260 3210144 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: mxa:MXAN_1575 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(3209260..3210144) Actinosynnema mirum DSM 43827 8326971 YP_003100562.1 CDS Amir_2783 NC_013093.1 3210249 3211157 D catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 3210249..3211157 Actinosynnema mirum DSM 43827 8326972 YP_003100563.1 CDS Amir_2784 NC_013093.1 3211195 3212049 R SMART: helix-turn-helix domain protein; KEGG: rle:RL4049 hypothetical protein; XRE family transcriptional regulator complement(3211195..3212049) Actinosynnema mirum DSM 43827 8326973 YP_003100564.1 CDS Amir_2785 NC_013093.1 3212175 3213638 D PFAM: Aldehyde Dehydrogenase; KEGG: swi:Swit_1745 aldehyde dehydrogenase (acceptor); aldehyde dehydrogenase 3212175..3213638 Actinosynnema mirum DSM 43827 8326974 YP_003100565.1 CDS Amir_2786 NC_013093.1 3213693 3213923 R hypothetical protein complement(3213693..3213923) Actinosynnema mirum DSM 43827 8326975 YP_003100566.1 CDS Amir_2787 NC_013093.1 3214052 3214627 D hypothetical protein 3214052..3214627 Actinosynnema mirum DSM 43827 8326976 YP_003100567.1 CDS Amir_2788 NC_013093.1 3214818 3215327 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rpc:RPC_1740 RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 3214818..3215327 Actinosynnema mirum DSM 43827 8326977 YP_003100568.1 CDS Amir_2790 NC_013093.1 3215811 3218000 R KEGG: bsu:BSU05430 hypothetical protein; hypothetical protein complement(3215811..3218000) Actinosynnema mirum DSM 43827 8326979 YP_003100569.1 CDS Amir_2791 NC_013093.1 3218032 3218571 R PFAM: regulatory protein TetR; KEGG: bav:BAV3196 TetR-family trasncriptional regulator; TetR family transcriptional regulator complement(3218032..3218571) Actinosynnema mirum DSM 43827 8326980 YP_003100570.1 CDS Amir_2792 NC_013093.1 3219015 3219581 D hypothetical protein 3219015..3219581 Actinosynnema mirum DSM 43827 8326981 YP_003100571.1 CDS Amir_2793 NC_013093.1 3219693 3220460 R PFAM: GAF domain protein; ANTAR domain protein; SMART: GAF domain protein; KEGG: sus:Acid_4463 GAF sensor protein; GAF domain-containing protein complement(3219693..3220460) Actinosynnema mirum DSM 43827 8326982 YP_003100572.1 CDS Amir_2794 NC_013093.1 3220753 3221253 D PFAM: protein of unknown function DUF322; KEGG: bha:BH2786 hypothetical protein; hypothetical protein 3220753..3221253 Actinosynnema mirum DSM 43827 8326983 YP_003100573.1 CDS Amir_2795 NC_013093.1 3221250 3221855 D KEGG: GH15499 gene product from transcript GH15499- RA; hypothetical protein 3221250..3221855 Actinosynnema mirum DSM 43827 8326984 YP_003100574.1 CDS Amir_2796 NC_013093.1 3221852 3222028 D hypothetical protein 3221852..3222028 Actinosynnema mirum DSM 43827 8326985 YP_003100575.1 CDS Amir_2797 NC_013093.1 3222034 3222447 D PFAM: protein of unknown function DUF322; KEGG: mes:Meso_4196 protein of unknown function DUF1403; hypothetical protein 3222034..3222447 Actinosynnema mirum DSM 43827 8326986 YP_003100576.1 CDS Amir_2798 NC_013093.1 3222444 3222989 D hypothetical protein 3222444..3222989 Actinosynnema mirum DSM 43827 8326987 YP_003100577.1 CDS Amir_2799 NC_013093.1 3222986 3223588 D hypothetical protein 3222986..3223588 Actinosynnema mirum DSM 43827 8326988 YP_003100578.1 CDS Amir_2800 NC_013093.1 3223578 3223868 D hypothetical protein 3223578..3223868 Actinosynnema mirum DSM 43827 8326989 YP_003100579.1 CDS Amir_2801 NC_013093.1 3223865 3224527 D hypothetical protein 3223865..3224527 Actinosynnema mirum DSM 43827 8326990 YP_003100580.1 CDS Amir_2803 NC_013093.1 3226027 3227190 R PFAM: glycosyl transferase group 1; KEGG: bmn:BMA10247_A2262 glycosyl transferase, group 1 family protein; group 1 glycosyl transferase complement(3226027..3227190) Actinosynnema mirum DSM 43827 8326992 YP_003100581.1 CDS Amir_2804 NC_013093.1 3227795 3228592 R PFAM: GAF domain protein; ANTAR domain protein; SMART: GAF domain protein; KEGG: sus:Acid_4463 GAF sensor protein; GAF domain-containing protein complement(3227795..3228592) Actinosynnema mirum DSM 43827 8326993 YP_003100582.1 CDS Amir_2805 NC_013093.1 3228634 3229410 R PFAM: ANTAR domain protein; GAF domain protein; SMART: GAF domain protein; KEGG: azo:azo1490 signaling protein; ANTAR domain-containing protein with unknown sensor complement(3228634..3229410) Actinosynnema mirum DSM 43827 8326994 YP_003100583.1 CDS Amir_2806 NC_013093.1 3229410 3230129 R KEGG: afw:Anae109_0792 GAF sensor signal transduction histidine kinase; hypothetical protein complement(3229410..3230129) Actinosynnema mirum DSM 43827 8326995 YP_003100584.1 CDS Amir_2807 NC_013093.1 3230224 3230691 R TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mag:amb0333 anti-anti-sigma regulatory factor; anti-sigma-factor antagonist complement(3230224..3230691) Actinosynnema mirum DSM 43827 8326996 YP_003100585.1 CDS Amir_2808 NC_013093.1 3231881 3232513 D KEGG: hypothetical protein; hypothetical protein 3231881..3232513 Actinosynnema mirum DSM 43827 8326997 YP_003100586.1 CDS Amir_2809 NC_013093.1 3232570 3232914 R hypothetical protein complement(3232570..3232914) Actinosynnema mirum DSM 43827 8326998 YP_003100587.1 CDS Amir_2810 NC_013093.1 3233060 3236017 D KEGG: GA27442 gene product from transcript GA27442- RA; hypothetical protein 3233060..3236017 Actinosynnema mirum DSM 43827 8326999 YP_003100588.1 CDS Amir_2811 NC_013093.1 3236050 3236703 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; response regulator receiver; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(3236050..3236703) Actinosynnema mirum DSM 43827 8327000 YP_003100589.1 CDS Amir_2813 NC_013093.1 3237954 3239747 D KEGG: hypothetical protein; hypothetical protein 3237954..3239747 Actinosynnema mirum DSM 43827 8327002 YP_003100590.1 CDS Amir_2814 NC_013093.1 3239824 3242874 D KEGG: hypothetical protein; hypothetical protein 3239824..3242874 Actinosynnema mirum DSM 43827 8327003 YP_003100591.1 CDS Amir_2815 NC_013093.1 3243288 3243986 D PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: sus:Acid_5291 methyltransferase type 11; type 12 methyltransferase 3243288..3243986 Actinosynnema mirum DSM 43827 8327004 YP_003100592.1 CDS Amir_2816 NC_013093.1 3244342 3245310 D PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: nwi:Nwi_2406 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 3244342..3245310 Actinosynnema mirum DSM 43827 8327005 YP_003100593.1 CDS Amir_2817 NC_013093.1 3245310 3246332 D PFAM: Radical SAM domain protein; KEGG: bma:BMAA1862 radical SAM domain-containing protein; Radical SAM domain-containing protein 3245310..3246332 Actinosynnema mirum DSM 43827 8327006 YP_003100594.1 CDS Amir_2818 NC_013093.1 3246335 3247291 D KEGG: smd:Smed_3106 hypothetical protein; hypothetical protein 3246335..3247291 Actinosynnema mirum DSM 43827 8327007 YP_003100595.1 CDS Amir_2819 NC_013093.1 3247288 3248643 D PFAM: glycosyl transferase group 1; KEGG: scl:sce0549 glycogen synthase; group 1 glycosyl transferase 3247288..3248643 Actinosynnema mirum DSM 43827 8327008 YP_003100596.1 CDS Amir_2820 NC_013093.1 3248640 3249332 D PFAM: LmbE family protein; KEGG: dar:Daro_1249 LmbE-like protein; LmbE family protein 3248640..3249332 Actinosynnema mirum DSM 43827 8327009 YP_003100597.1 CDS Amir_2821 NC_013093.1 3249317 3250315 D TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KR domain protein; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; short- chain dehydrogenase/reductase SDR; KEGG: bcj:BCAM2033 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 3249317..3250315 Actinosynnema mirum DSM 43827 8327010 YP_003100598.1 CDS Amir_2822 NC_013093.1 3250306 3250977 D PFAM: phosphoglycerate mutase; KEGG: afr:AFE_0621 phosphoglycerate mutase family protein; phosphoglycerate mutase 3250306..3250977 Actinosynnema mirum DSM 43827 8327011 YP_003100599.1 CDS Amir_2823 NC_013093.1 3250974 3252506 D PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: predicted protein; type I phosphodiesterase/nucleotide pyrophosphatase 3250974..3252506 Actinosynnema mirum DSM 43827 8327012 YP_003100600.1 CDS Amir_2824 NC_013093.1 3252503 3253411 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mch:Mchl_0500 ABC transporter; ABC transporter 3252503..3253411 Actinosynnema mirum DSM 43827 8327013 YP_003100601.1 CDS Amir_2825 NC_013093.1 3253401 3254162 D PFAM: ABC transporter; KEGG: bte:BTH_I2328 transporter; ABC transporter 3253401..3254162 Actinosynnema mirum DSM 43827 8327014 YP_003100602.1 CDS Amir_2826 NC_013093.1 3254217 3254456 D PFAM: phosphopantetheine-binding; KEGG: pol:Bpro_3393 AMP-dependent synthetase and ligase; phosphopantetheine-binding 3254217..3254456 Actinosynnema mirum DSM 43827 8327015 YP_003100603.1 CDS Amir_2828 NC_013093.1 3255291 3256208 R PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_2144 NmrA-like family protein; NmrA family protein complement(3255291..3256208) Actinosynnema mirum DSM 43827 8327017 YP_003100604.1 CDS Amir_2829 NC_013093.1 3256365 3256976 D PFAM: regulatory protein TetR; KEGG: mxa:MXAN_2145 transcriptional regulator, TetR family; TetR family transcriptional regulator 3256365..3256976 Actinosynnema mirum DSM 43827 8327018 YP_003100605.1 CDS Amir_2830 NC_013093.1 3256957 3257991 R KEGG: smd:Smed_4158 alanine racemase; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(3256957..3257991) Actinosynnema mirum DSM 43827 8327019 YP_003100606.1 CDS Amir_2831 NC_013093.1 3258637 3260526 D PFAM: protein of unknown function DUF1680; KEGG: ret:RHE_CH03841 hypothetical protein; hypothetical protein 3258637..3260526 Actinosynnema mirum DSM 43827 8327020 YP_003100607.1 CDS Amir_2832 NC_013093.1 3260564 3261817 D PFAM: extracellular solute-binding protein family 1; KEGG: mlo:mlr2244 sugar binding protein of sugar ABC transporter; family 1 extracellular solute-binding protein 3260564..3261817 Actinosynnema mirum DSM 43827 8327021 YP_003100608.1 CDS Amir_2833 NC_013093.1 3261825 3262772 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 3261825..3262772 Actinosynnema mirum DSM 43827 8327022 YP_003100609.1 CDS Amir_2834 NC_013093.1 3262787 3263614 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL4375 transmembrane component of ABC transporter; ABC transporter inner membrane protein 3262787..3263614 Actinosynnema mirum DSM 43827 8327023 YP_003100610.1 CDS Amir_2835 NC_013093.1 3263676 3264551 D KEGG: hypothetical protein; hypothetical protein 3263676..3264551 Actinosynnema mirum DSM 43827 8327024 YP_003100611.1 CDS Amir_2836 NC_013093.1 3264702 3266546 D PFAM: protein of unknown function DUF1680; KEGG: hypothetical protein; hypothetical protein 3264702..3266546 Actinosynnema mirum DSM 43827 8327025 YP_003100612.1 CDS Amir_2837 NC_013093.1 3266602 3267648 D PFAM: glycoside hydrolase family 43; KEGG: scl:sce4598 endo-1,4-beta-xylanase; glycoside hydrolase family protein 3266602..3267648 Actinosynnema mirum DSM 43827 8327026 YP_003100613.1 CDS Amir_2838 NC_013093.1 3267645 3270485 D PFAM: coagulation factor 5/8 type domain protein; KEGG: xcv:XCV2729 secreted protein; coagulation factor 5/8 type domain-containing protein 3267645..3270485 Actinosynnema mirum DSM 43827 8327027 YP_003100614.1 CDS Amir_2839 NC_013093.1 3270537 3272090 R PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein complement(3270537..3272090) Actinosynnema mirum DSM 43827 8327028 YP_003100615.1 CDS Amir_2840 NC_013093.1 3272204 3272539 R PFAM: ethyl tert-butyl ether degradation EthD; KEGG: cak:Caul_5271 ethyl tert-butyl ether degradation EthD; ethyl tert-butyl ether degradation protein EthD complement(3272204..3272539) Actinosynnema mirum DSM 43827 8327029 YP_003100616.1 CDS Amir_2841 NC_013093.1 3272689 3273066 D PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcr:BCAH187_A5339 transcriptional regulator, MerR family; MerR family transcriptional regulator 3272689..3273066 Actinosynnema mirum DSM 43827 8327030 YP_003100617.1 CDS Amir_2842 NC_013093.1 3273281 3274759 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: acp:A2cp1_0906 transcriptional regulator, LuxR family; LuxR family transcriptional regulator 3273281..3274759 Actinosynnema mirum DSM 43827 8327031 YP_003100618.1 CDS Amir_2843 NC_013093.1 3274711 3275091 R PFAM: endoribonuclease L-PSP; KEGG: bja:bll4888 hypothetical protein; endoribonuclease L-PSP complement(3274711..3275091) Actinosynnema mirum DSM 43827 8327032 YP_003100619.1 CDS Amir_2844 NC_013093.1 3275193 3275588 R hypothetical protein complement(3275193..3275588) Actinosynnema mirum DSM 43827 8327033 YP_003100620.1 CDS Amir_2845 NC_013093.1 3275804 3276457 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: dvm:DvMF_1479 transcriptional regulator, GntR family; GntR family transcriptional regulator complement(3275804..3276457) Actinosynnema mirum DSM 43827 8327034 YP_003100621.1 CDS Amir_2846 NC_013093.1 3276471 3278195 R PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: rme:Rmet_5039 acetolactate synthase, large subunit; thiamine pyrophosphate TPP-binding domain-containing protein complement(3276471..3278195) Actinosynnema mirum DSM 43827 8327035 YP_003100622.1 CDS Amir_2847 NC_013093.1 3278192 3279709 R KEGG: sal:Sala_2314 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein; amidohydrolase complement(3278192..3279709) Actinosynnema mirum DSM 43827 8327036 YP_003100623.1 CDS Amir_2848 NC_013093.1 3279706 3280626 R PFAM: luciferase-like monooxygenase; KEGG: rpb:RPB_4411 luciferase-like; luciferase-like monooxygenase complement(3279706..3280626) Actinosynnema mirum DSM 43827 8327037 YP_003100624.1 CDS Amir_2849 NC_013093.1 3280623 3282509 R PFAM: hydantoinase B/oxoprolinase; KEGG: mes:Meso_3732 hydantoinase B/oxoprolinase; 5-oxoprolinase complement(3280623..3282509) Actinosynnema mirum DSM 43827 8327038 YP_003100625.1 CDS Amir_2850 NC_013093.1 3282502 3284574 R PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; KEGG: mno:Mnod_8488 hydantoinase/oxoprolinase; 5-oxoprolinase complement(3282502..3284574) Actinosynnema mirum DSM 43827 8327039 YP_003100626.1 CDS Amir_2851 NC_013093.1 3284571 3285392 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL100063 ABC transporter permease component; ABC transporter inner membrane protein complement(3284571..3285392) Actinosynnema mirum DSM 43827 8327040 YP_003100627.1 CDS Amir_2852 NC_013093.1 3285389 3286228 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oca:OCAR_6772 ABC transporter; ABC transporter inner membrane protein complement(3285389..3286228) Actinosynnema mirum DSM 43827 8327041 YP_003100628.1 CDS Amir_2853 NC_013093.1 3286225 3287322 R PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: azc:AZC_2725 ABC transporter ATP-binding protein; ABC transporter complement(3286225..3287322) Actinosynnema mirum DSM 43827 8327042 YP_003100629.1 CDS Amir_2854 NC_013093.1 3287324 3288427 R KEGG: bph:Bphy_6624 extracellular solute-binding protein; spermidine/putrescine-binding periplasmic protein complement(3287324..3288427) Actinosynnema mirum DSM 43827 8327043 YP_003100630.1 CDS Amir_2855 NC_013093.1 3288721 3289413 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mmw:Mmwyl1_4073 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3288721..3289413 Actinosynnema mirum DSM 43827 8327044 YP_003100631.1 CDS Amir_2856 NC_013093.1 3289517 3290218 R KEGG: hch:HCH_03068 lysophospholipase; hypothetical protein complement(3289517..3290218) Actinosynnema mirum DSM 43827 8327045 YP_003100632.1 CDS Amir_2857 NC_013093.1 3290328 3291308 D PFAM: Helix-turn-helix type 11 domain protein; protein of unknown function UPF0074; KEGG: pol:Bpro_0147 helix-turn-helix, type 11; Helix-turn-helix type 11 domain-containing protein 3290328..3291308 Actinosynnema mirum DSM 43827 8327046 YP_003100633.1 CDS Amir_2858 NC_013093.1 3291609 3293006 R PFAM: major facilitator superfamily MFS_1; KEGG: eum:ECUMN_4826 conserved hypothetical protein mrx; major facilitator superfamily protein complement(3291609..3293006) Actinosynnema mirum DSM 43827 8327047 YP_003100634.1 CDS Amir_2859 NC_013093.1 3293115 3293675 D PFAM: regulatory protein TetR; KEGG: ccs:CCNA_02884 transcriptional regulator, TetR family; TetR family transcriptional regulator 3293115..3293675 Actinosynnema mirum DSM 43827 8327048 YP_003100635.1 CDS Amir_2860 NC_013093.1 3293698 3294435 R KEGG: mxa:MXAN_2224 hypothetical protein; hypothetical protein complement(3293698..3294435) Actinosynnema mirum DSM 43827 8327049 YP_003100636.1 CDS Amir_2861 NC_013093.1 3294839 3295240 D KEGG: similar to bromodomain adjacent to zinc finger domain, 1B; K11658 bromodomain adjacent to zinc finger domain protein 1B; hypothetical protein 3294839..3295240 Actinosynnema mirum DSM 43827 8327050 YP_003100637.1 CDS Amir_2862 NC_013093.1 3295237 3296715 R PFAM: Extracellular ligand-binding receptor; KEGG: cvi:CV_0405 amino acid ABC transporter; Extracellular ligand-binding receptor complement(3295237..3296715) Actinosynnema mirum DSM 43827 8327051 YP_003100638.1 CDS Amir_2863 NC_013093.1 3296759 3298456 R KEGG: hypothetical protein; hypothetical protein complement(3296759..3298456) Actinosynnema mirum DSM 43827 8327052 YP_003100639.1 CDS Amir_2865 NC_013093.1 3299537 3302266 R KEGG: eca:ECA4303 hypothetical protein; hypothetical protein complement(3299537..3302266) Actinosynnema mirum DSM 43827 8327054 YP_003100640.1 CDS Amir_2866 NC_013093.1 3302549 3302875 D hypothetical protein 3302549..3302875 Actinosynnema mirum DSM 43827 8327055 YP_003100641.1 CDS Amir_2867 NC_013093.1 3302872 3303567 D KEGG: mpo:Mpop_2368 GLUG domain protein; hypothetical protein 3302872..3303567 Actinosynnema mirum DSM 43827 8327056 YP_003100642.1 CDS Amir_2868 NC_013093.1 3304515 3304679 R hypothetical protein complement(3304515..3304679) Actinosynnema mirum DSM 43827 8327057 YP_003100643.1 CDS Amir_2869 NC_013093.1 3304757 3305023 R hypothetical protein complement(3304757..3305023) Actinosynnema mirum DSM 43827 8327058 YP_003100644.1 CDS Amir_2870 NC_013093.1 3306210 3312644 D TIGRFAM: YD repeat protein; KEGG: ypp:YPDSF_0222 membrane protein; YD repeat-containing protein 3306210..3312644 Actinosynnema mirum DSM 43827 8327059 YP_003100645.1 CDS Amir_2871 NC_013093.1 3313133 3314707 R PFAM: Domain of unknown function DUF1814; KEGG: scl:sce3078 hydrolase; hypothetical protein complement(3313133..3314707) Actinosynnema mirum DSM 43827 8327060 YP_003100646.1 CDS Amir_2872 NC_013093.1 3314890 3315294 D PFAM: Rare lipoprotein A; KEGG: lipoprotein A domain-containing protein; Rare lipoprotein A 3314890..3315294 Actinosynnema mirum DSM 43827 8327061 YP_003100647.1 CDS Amir_2873 NC_013093.1 3315415 3316509 D PFAM: periplasmic binding protein; KEGG: dsh:Dshi_0573 periplasmic binding protein; periplasmic binding protein 3315415..3316509 Actinosynnema mirum DSM 43827 8327062 YP_003100648.1 CDS Amir_2874 NC_013093.1 3316506 3317588 D PFAM: transport system permease protein; KEGG: rce:RC1_3860 hemin transport system permease protein HmuU; transport system permease 3316506..3317588 Actinosynnema mirum DSM 43827 8327063 YP_003100649.1 CDS hmuV NC_013093.1 3317585 3318403 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3317585..3318403 Actinosynnema mirum DSM 43827 8327064 YP_003100650.1 CDS Amir_2876 NC_013093.1 3318403 3319500 D KEGG: cti:RALTA_B2062 conserved hypothetical protein; exported protein; hypothetical protein 3318403..3319500 Actinosynnema mirum DSM 43827 8327065 YP_003100651.1 CDS Amir_2877 NC_013093.1 3319497 3320540 D TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Htaa domain protein; KEGG: GJ12556 gene product from transcript GJ12556- RA; LPXTG-motif cell wall anchor domain-containing protein 3319497..3320540 Actinosynnema mirum DSM 43827 8327066 YP_003100652.1 CDS Amir_2878 NC_013093.1 3320578 3321714 R PFAM: monooxygenase FAD-binding; KEGG: gdj:Gdia_2837 monooxygenase FAD-binding; FAD-binding monooxygenase complement(3320578..3321714) Actinosynnema mirum DSM 43827 8327067 YP_003100653.1 CDS Amir_2879 NC_013093.1 3321789 3322469 D PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: bur:Bcep18194_B0744 TetR family transcriptional regulator; TetR family transcriptional regulator 3321789..3322469 Actinosynnema mirum DSM 43827 8327068 YP_003100654.1 CDS Amir_2880 NC_013093.1 3322501 3323601 R PFAM: protein of unknown function DUF916 cell surface KEGG: mex:Mext_2409 hypothetical protein; hypothetical protein complement(3322501..3323601) Actinosynnema mirum DSM 43827 8327069 YP_003100655.1 CDS Amir_2881 NC_013093.1 3323661 3324998 R KEGG: hypothetical protein; hypothetical protein complement(3323661..3324998) Actinosynnema mirum DSM 43827 8327070 YP_003100656.1 CDS Amir_2882 NC_013093.1 3325147 3325743 R PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mpt:Mpe_A2158 phosphoribosylanthranilate isomerase; phosphoribosylanthranilate isomerase complement(3325147..3325743) Actinosynnema mirum DSM 43827 8327071 YP_003100657.1 CDS Amir_2883 NC_013093.1 3325794 3326375 D TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD family protein; HhH-GPD family protein 3325794..3326375 Actinosynnema mirum DSM 43827 8327072 YP_003100658.1 CDS Amir_2885 NC_013093.1 3326757 3329027 D KEGG: YALI0B09867p; hypothetical protein 3326757..3329027 Actinosynnema mirum DSM 43827 8327074 YP_003100659.1 CDS Amir_2886 NC_013093.1 3329188 3330075 D KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein 3329188..3330075 Actinosynnema mirum DSM 43827 8327075 YP_003100660.1 CDS Amir_2887 NC_013093.1 3330390 3330704 R PFAM: small multidrug resistance protein; KEGG: pzu:PHZ_c0240 small multidrug resistance protein; small multidrug resistance protein complement(3330390..3330704) Actinosynnema mirum DSM 43827 8327076 YP_003100661.1 CDS Amir_2888 NC_013093.1 3331030 3332478 R PFAM: major facilitator superfamily MFS_1; KEGG: sal:Sala_0898 major facilitator transporter; major facilitator superfamily protein complement(3331030..3332478) Actinosynnema mirum DSM 43827 8327077 YP_003100662.1 CDS Amir_2889 NC_013093.1 3332639 3333322 D PFAM: regulatory protein TetR; KEGG: pla:Plav_0388 TetR family transcriptional regulator; TetR family transcriptional regulator 3332639..3333322 Actinosynnema mirum DSM 43827 8327078 YP_003100663.1 CDS Amir_2890 NC_013093.1 3333994 3334248 D KEGG: cell wall protein; hypothetical protein 3333994..3334248 Actinosynnema mirum DSM 43827 8327079 YP_003100664.1 CDS Amir_2891 NC_013093.1 3334245 3334955 D PFAM: regulatory protein TetR; KEGG: swi:Swit_1768 regulatory protein, TetR; TetR family transcriptional regulator 3334245..3334955 Actinosynnema mirum DSM 43827 8327080 YP_003100665.1 CDS Amir_2892 NC_013093.1 3334952 3335152 D PFAM: protein of unknown function DUF1271; KEGG: bxe:Bxe_C0944 ferredoxin; hypothetical protein 3334952..3335152 Actinosynnema mirum DSM 43827 8327081 YP_003100666.1 CDS Amir_2893 NC_013093.1 3335149 3336585 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: met:M446_4600 cyclic nucleotide-binding protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 3335149..3336585 Actinosynnema mirum DSM 43827 8327082 YP_003100667.1 CDS Amir_2894 NC_013093.1 3336582 3337805 D PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 3336582..3337805 Actinosynnema mirum DSM 43827 8327083 YP_003100668.1 CDS Amir_2895 NC_013093.1 3337898 3339103 D PFAM: cytochrome P450; KEGG: CYP55B1; cytochrome P450, nitric oxide reductase; cytochrome P450 3337898..3339103 Actinosynnema mirum DSM 43827 8327084 YP_003100669.1 CDS Amir_2896 NC_013093.1 3339117 3340109 D TIGRFAM: glycosyltransferase, MGT family; PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; glycosyltransferase 28 domain; KEGG: ses:SARI_00205 hypothetical protein; MGT family glycosyltransferase 3339117..3340109 Actinosynnema mirum DSM 43827 8327085 YP_003100670.1 CDS Amir_2897 NC_013093.1 3340812 3342527 D PFAM: histidine kinase A domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: bxe:Bxe_A0786 lipoprotein; histidine kinase 3340812..3342527 Actinosynnema mirum DSM 43827 8327086 YP_003100671.1 CDS Amir_2898 NC_013093.1 3342548 3343396 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcz:pE33L466_0331 MerR family transcriptional regulator; MerR family transcriptional regulator complement(3342548..3343396) Actinosynnema mirum DSM 43827 8327087 YP_003100672.1 CDS Amir_2899 NC_013093.1 3343645 3345093 R PFAM: amidohydrolase; Amidohydrolase 3; KEGG: reu:Reut_C6231 hypothetical protein; amidohydrolase complement(3343645..3345093) Actinosynnema mirum DSM 43827 8327088 YP_003100673.1 CDS Amir_2900 NC_013093.1 3345176 3345781 D PFAM: regulatory protein TetR; KEGG: xau:Xaut_3070 TetR family transcriptional regulator; TetR family transcriptional regulator 3345176..3345781 Actinosynnema mirum DSM 43827 8327089 YP_003100674.1 CDS Amir_2901 NC_013093.1 3345848 3347203 R PFAM: AMP-dependent synthetase and ligase; KEGG: pen:PSEEN2716 non-ribosomal peptide synthetase; AMP-dependent synthetase and ligase complement(3345848..3347203) Actinosynnema mirum DSM 43827 8327090 YP_003100675.1 CDS Amir_2907 NC_013093.1 3351047 3352924 D KEGG: GD20599 gene product from transcript GD20599- RA; hypothetical protein 3351047..3352924 Actinosynnema mirum DSM 43827 8327096 YP_003100676.1 CDS Amir_2908 NC_013093.1 3352971 3354476 R PFAM: extracellular solute-binding protein family 5; KEGG: extracellular solute-binding protein; K02035 peptide/nickel transport system substrate-binding protein; family 5 extracellular solute-binding protein complement(3352971..3354476) Actinosynnema mirum DSM 43827 8327097 YP_003100677.1 CDS Amir_2909 NC_013093.1 3355008 3358358 D KEGG: efe:EFER_2201 molybdate metabolism regulator (MolR); hypothetical protein 3355008..3358358 Actinosynnema mirum DSM 43827 8327098 YP_003100678.1 CDS Amir_2910 NC_013093.1 3358541 3360892 R PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-2 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; KEGG: sml:Smlt2382 two-component sensor histidine kinase protein; multi-sensor signal transduction histidine kinase complement(3358541..3360892) Actinosynnema mirum DSM 43827 8327099 YP_003100679.1 CDS Amir_2911 NC_013093.1 3361009 3362985 D PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sus:Acid_5974 serine phosphatase; protein serine/threonine phosphatase 3361009..3362985 Actinosynnema mirum DSM 43827 8327100 YP_003100680.1 CDS Amir_2912 NC_013093.1 3362964 3363389 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mag:amb3470 FOG: CheY-like receiver; response regulator receiver protein 3362964..3363389 Actinosynnema mirum DSM 43827 8327101 YP_003100681.1 CDS Amir_2913 NC_013093.1 3363559 3363855 D hypothetical protein 3363559..3363855 Actinosynnema mirum DSM 43827 8327102 YP_003100682.1 CDS Amir_2915 NC_013093.1 3366125 3366565 D PFAM: helix-turn-helix HxlR type; KEGG: mxa:MXAN_5099 transcriptional regulator; HxlR family transcriptional regulator 3366125..3366565 Actinosynnema mirum DSM 43827 8327104 YP_003100683.1 CDS Amir_2916 NC_013093.1 3366690 3367475 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cak:Caul_1370 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3366690..3367475 Actinosynnema mirum DSM 43827 8327105 YP_003100684.1 CDS Amir_2917 NC_013093.1 3367435 3368103 R KEGG: hypothetical protein LOC686639; hypothetical protein complement(3367435..3368103) Actinosynnema mirum DSM 43827 8327106 YP_003100685.1 CDS Amir_2918 NC_013093.1 3368109 3368981 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL120663 permease component of ABC transporter; ABC transporter inner membrane protein complement(3368109..3368981) Actinosynnema mirum DSM 43827 8327107 YP_003100686.1 CDS Amir_2919 NC_013093.1 3368978 3369910 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ABC transporter membrane spanning protein (sugar); K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein complement(3368978..3369910) Actinosynnema mirum DSM 43827 8327108 YP_003100687.1 CDS Amir_2920 NC_013093.1 3369915 3371189 R PFAM: extracellular solute-binding protein family 1; KEGG: rle:pRL120659 substrate-binding component of ABC transporter; family 1 extracellular solute-binding protein complement(3369915..3371189) Actinosynnema mirum DSM 43827 8327109 YP_003100688.1 CDS Amir_2921 NC_013093.1 3371235 3373190 R KEGG: ret:RHE_CH00075 hypothetical protein; hypothetical protein complement(3371235..3373190) Actinosynnema mirum DSM 43827 8327110 YP_003100689.1 CDS Amir_2922 NC_013093.1 3373187 3374167 R PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rlt:Rleg2_4009 D-isomer specific 2- hydroxyacid dehydrogenase NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase complement(3373187..3374167) Actinosynnema mirum DSM 43827 8327111 YP_003100690.1 CDS Amir_2923 NC_013093.1 3374356 3375444 D PFAM: regulatory protein DeoR; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein DeoR; KEGG: ppw:PputW619_1959 LacI family transcription regulator; DeoR family transcriptional regulator 3374356..3375444 Actinosynnema mirum DSM 43827 8327112 YP_003100691.1 CDS Amir_2924 NC_013093.1 3375820 3376701 D PFAM: conserved hypothetical protein; KEGG: ade:Adeh_2416 hypothetical protein; hypothetical protein 3375820..3376701 Actinosynnema mirum DSM 43827 8327113 YP_003100692.1 CDS Amir_2925 NC_013093.1 3376705 3378711 R PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; SARP family transcriptional regulator complement(3376705..3378711) Actinosynnema mirum DSM 43827 8327114 YP_003100693.1 CDS Amir_2926 NC_013093.1 3378911 3379252 D hypothetical protein 3378911..3379252 Actinosynnema mirum DSM 43827 8327115 YP_003100694.1 CDS Amir_2927 NC_013093.1 3379249 3379506 D hypothetical protein 3379249..3379506 Actinosynnema mirum DSM 43827 8327116 YP_003100695.1 CDS Amir_2928 NC_013093.1 3380126 3380290 D hypothetical protein 3380126..3380290 Actinosynnema mirum DSM 43827 8327117 YP_003100696.1 CDS Amir_2929 NC_013093.1 3380342 3381685 R KEGG: GM17356 gene product from transcript GM17356- RA; hypothetical protein complement(3380342..3381685) Actinosynnema mirum DSM 43827 8327118 YP_003100697.1 CDS Amir_2930 NC_013093.1 3381835 3382461 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: bcy:Bcer98_1160 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 3381835..3382461 Actinosynnema mirum DSM 43827 8327119 YP_003100698.1 CDS Amir_2931 NC_013093.1 3382591 3385680 D PFAM: hypothetical protein; KEGG: ade:Adeh_2230 hypothetical protein; hypothetical protein 3382591..3385680 Actinosynnema mirum DSM 43827 8327120 YP_003100699.1 CDS Amir_2932 NC_013093.1 3385733 3386458 D KEGG: plu:plu1715 hypothetical protein; hypothetical protein 3385733..3386458 Actinosynnema mirum DSM 43827 8327121 YP_003100700.1 CDS Amir_2933 NC_013093.1 3386532 3388601 D PFAM: ATPase AAA; SMART: ATPase AAA; KEGG: noc:Noc_1879 ATPase AAA; ATPase AAA 3386532..3388601 Actinosynnema mirum DSM 43827 8327122 YP_003100701.1 CDS Amir_2934 NC_013093.1 3388642 3389502 R KEGG: aci:ACIAD3520 hypothetical protein; hypothetical protein complement(3388642..3389502) Actinosynnema mirum DSM 43827 8327123 YP_003100702.1 CDS Amir_2935 NC_013093.1 3389649 3390107 D hypothetical protein 3389649..3390107 Actinosynnema mirum DSM 43827 8327124 YP_003100703.1 CDS Amir_2936 NC_013093.1 3390127 3393291 R PFAM: transcriptional activator domain; TPR repeat- containing protein; hypothetical protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce6858 hypothetical protein; SARP family transcriptional regulator complement(3390127..3393291) Actinosynnema mirum DSM 43827 8327125 YP_003100704.1 CDS Amir_2937 NC_013093.1 3393516 3393725 D KEGG: bpy:Bphyt_1629 pseudouridine synthase; pseudouridine synthase 3393516..3393725 Actinosynnema mirum DSM 43827 8327126 YP_003100705.1 CDS Amir_2938 NC_013093.1 3394111 3395640 D PFAM: tail sheath protein; KEGG: mlo:mlr6548 hypothetical protein; tail sheath protein 3394111..3395640 Actinosynnema mirum DSM 43827 8327127 YP_003100706.1 CDS Amir_2939 NC_013093.1 3395687 3396127 D TIGRFAM: conserved hypothetical protein; KEGG: gsu:GSU0979 hypothetical protein; hypothetical protein 3395687..3396127 Actinosynnema mirum DSM 43827 8327128 YP_003100707.1 CDS Amir_2940 NC_013093.1 3396124 3396624 D KEGG: gsu:GSU0977 hypothetical protein; hypothetical protein 3396124..3396624 Actinosynnema mirum DSM 43827 8327129 YP_003100708.1 CDS Amir_2941 NC_013093.1 3396621 3396779 D KEGG: mlo:msr6553 hypothetical protein; hypothetical protein 3396621..3396779 Actinosynnema mirum DSM 43827 8327130 YP_003100709.1 CDS Amir_2942 NC_013093.1 3396884 3399646 D KEGG: proteophosphoglycan 5; hypothetical protein 3396884..3399646 Actinosynnema mirum DSM 43827 8327131 YP_003100710.1 CDS Amir_2943 NC_013093.1 3399697 3400122 D TIGRFAM: conserved hypothetical protein; KEGG: noc:Noc_1873 phage tail region protein; hypothetical protein 3399697..3400122 Actinosynnema mirum DSM 43827 8327132 YP_003100711.1 CDS Amir_2944 NC_013093.1 3400147 3400857 D PFAM: peptidoglycan-binding LysM; KEGG: gsu:GSU0981 hypothetical protein; peptidoglycan-binding LysM 3400147..3400857 Actinosynnema mirum DSM 43827 8327133 YP_003100712.1 CDS Amir_2945 NC_013093.1 3400854 3402623 D TIGRFAM: Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: gbm:Gbem_2550 rhs element Vgr protein; Rhs element Vgr protein 3400854..3402623 Actinosynnema mirum DSM 43827 8327134 YP_003100713.1 CDS Amir_2946 NC_013093.1 3402657 3402968 D PFAM: hypothetical protein; KEGG: sde:Sde_1043 hypothetical protein; hypothetical protein 3402657..3402968 Actinosynnema mirum DSM 43827 8327135 YP_003100714.1 CDS Amir_2947 NC_013093.1 3402965 3403372 D PFAM: GPW/gp25 family protein; KEGG: gsu:GSU0986 tail lysozyme; GPW/gp25 family protein 3402965..3403372 Actinosynnema mirum DSM 43827 8327136 YP_003100715.1 CDS Amir_2948 NC_013093.1 3403372 3405324 D KEGG: gsu:GSU0988 hypothetical protein; hypothetical protein 3403372..3405324 Actinosynnema mirum DSM 43827 8327137 YP_003100716.1 CDS Amir_2949 NC_013093.1 3405321 3405896 D TIGRFAM: phage tail protein; KEGG: rsq:Rsph17025_4353 hypothetical protein; phage tail protein 3405321..3405896 Actinosynnema mirum DSM 43827 8327138 YP_003100717.1 CDS Amir_2950 NC_013093.1 3406304 3407299 D KEGG: similar to Enabled protein homolog; K05746 enabled; hypothetical protein 3406304..3407299 Actinosynnema mirum DSM 43827 8327139 YP_003100718.1 CDS Amir_2951 NC_013093.1 3407328 3408353 D PFAM: NAD-dependent epimerase/dehydratase; KEGG: mgm:Mmc1_2871 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 3407328..3408353 Actinosynnema mirum DSM 43827 8327140 YP_003100719.1 CDS Amir_2952 NC_013093.1 3408427 3409050 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: bcy:Bcer98_0214 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 3408427..3409050 Actinosynnema mirum DSM 43827 8327141 YP_003100720.1 CDS Amir_2953 NC_013093.1 3409052 3409291 D hypothetical protein 3409052..3409291 Actinosynnema mirum DSM 43827 8327142 YP_003100721.1 CDS Amir_2954 NC_013093.1 3409582 3413022 R PFAM: transcriptional activator domain; hypothetical protein; transcriptional regulator domain protein; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; transcriptional regulator complement(3409582..3413022) Actinosynnema mirum DSM 43827 8327143 YP_003100722.1 CDS Amir_2955 NC_013093.1 3413019 3413336 R KEGG: bbr:BB2134 hypothetical protein; hypothetical protein complement(3413019..3413336) Actinosynnema mirum DSM 43827 8327144 YP_003100723.1 CDS Amir_2956 NC_013093.1 3413350 3417369 R PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: bpm:BURPS1710b_1102 lipoprotein; transcriptional regulator complement(3413350..3417369) Actinosynnema mirum DSM 43827 8327145 YP_003100724.1 CDS Amir_2957 NC_013093.1 3418122 3418556 D PFAM: UspA domain protein; KEGG: hha:Hhal_2190 UspA domain protein; UspA domain-containing protein 3418122..3418556 Actinosynnema mirum DSM 43827 8327146 YP_003100725.1 CDS Amir_2958 NC_013093.1 3418810 3419277 D hypothetical protein 3418810..3419277 Actinosynnema mirum DSM 43827 8327147 YP_003100726.1 CDS Amir_2959 NC_013093.1 3419337 3420461 D PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pat:Patl_1928 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 3419337..3420461 Actinosynnema mirum DSM 43827 8327148 YP_003100727.1 CDS Amir_2960 NC_013093.1 3420792 3421010 D hypothetical protein 3420792..3421010 Actinosynnema mirum DSM 43827 8327149 YP_003100728.1 CDS Amir_2961 NC_013093.1 3421087 3421671 R KEGG: cvi:CV_3666 acetyltransferase; hypothetical protein complement(3421087..3421671) Actinosynnema mirum DSM 43827 8327150 YP_003100729.1 CDS Amir_2962 NC_013093.1 3421661 3422005 R KEGG: GM10273 gene product from transcript GM10273- RA; hypothetical protein complement(3421661..3422005) Actinosynnema mirum DSM 43827 8327151 YP_003100730.1 CDS Amir_2963 NC_013093.1 3422077 3422538 R hypothetical protein complement(3422077..3422538) Actinosynnema mirum DSM 43827 8327152 YP_003100731.1 CDS Amir_2964 NC_013093.1 3423093 3425117 D KEGG: cti:RALTA_A1696 DNA ligase; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD- dependent DNA ligase OB-fold; SMART: NAD-dependent DNA ligase; BRCT domain protein; Helix-hairpin-helix DNA-binding class 1; DNA ligase, NAD-dependent 3423093..3425117 Actinosynnema mirum DSM 43827 8327153 YP_003100732.1 CDS Amir_2966 NC_013093.1 3428249 3431500 D KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 3428249..3431500 Actinosynnema mirum DSM 43827 8327155 YP_003100733.1 CDS Amir_2967 NC_013093.1 3431766 3432920 R PFAM: aminotransferase class I and II; KEGG: dvl:Dvul_2797 aminotransferase, class I and II; class I and II aminotransferase complement(3431766..3432920) Actinosynnema mirum DSM 43827 8327156 YP_003100734.1 CDS Amir_2968 NC_013093.1 3432871 3434229 D KEGG: xca:xccb100_4160 secreted hydrolase; hypothetical protein 3432871..3434229 Actinosynnema mirum DSM 43827 8327157 YP_003100735.1 CDS Amir_2969 NC_013093.1 3434570 3435088 D PFAM: ATP-binding region ATPase domain protein; KEGG: mpt:Mpe_A0358 two-component sensor histidine kinase-like protein; signal transduction histidine kinase 3434570..3435088 Actinosynnema mirum DSM 43827 8327158 YP_003100736.1 CDS Amir_2970 NC_013093.1 3435371 3436999 D PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: sde:Sde_0644 hypothetical protein; TAP domain-containing protein 3435371..3436999 Actinosynnema mirum DSM 43827 8327159 YP_003100737.1 CDS Amir_2971 NC_013093.1 3437157 3438014 D KEGG: hypothetical protein; K10592 E3 ubiquitin- protein ligase HUWE1; hypothetical protein 3437157..3438014 Actinosynnema mirum DSM 43827 8327160 YP_003100738.1 CDS Amir_2972 NC_013093.1 3438326 3439063 D PFAM: xylose isomerase; KEGG: lch:Lcho_4327 xylose isomerase domain- containing protein; xylose isomerase 3438326..3439063 Actinosynnema mirum DSM 43827 8327161 YP_003100739.1 CDS Amir_2973 NC_013093.1 3439060 3440160 D PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: rec:RHECIAT_CH0002098 dehydrogenase protein; oxidoreductase domain-containing protein 3439060..3440160 Actinosynnema mirum DSM 43827 8327162 YP_003100740.1 CDS Amir_2974 NC_013093.1 3440231 3440830 R PFAM: regulatory protein TetR; KEGG: pst:PSPTO_3319 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3440231..3440830) Actinosynnema mirum DSM 43827 8327163 YP_003100741.1 CDS Amir_2975 NC_013093.1 3440915 3441352 R hypothetical protein complement(3440915..3441352) Actinosynnema mirum DSM 43827 8327164 YP_003100742.1 CDS Amir_2976 NC_013093.1 3441467 3441955 R PFAM: NUDIX hydrolase; KEGG: bce:BC3339 phosphohydrolase (MutT/NUDIX family protein); NUDIX hydrolase complement(3441467..3441955) Actinosynnema mirum DSM 43827 8327165 YP_003100743.1 CDS Amir_2977 NC_013093.1 3442342 3442932 R PFAM: regulatory protein TetR; KEGG: psb:Psyr_3154 regulatory protein, TetR; TetR family transcriptional regulator complement(3442342..3442932) Actinosynnema mirum DSM 43827 8327166 YP_003100744.1 CDS Amir_2978 NC_013093.1 3442929 3444758 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: beta-glucosidase-related glycosidases; xylan 1,4-beta-xylosidase complement(3442929..3444758) Actinosynnema mirum DSM 43827 8327167 YP_003100745.1 CDS Amir_2979 NC_013093.1 3444924 3446189 D PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: floR; florfenicol/chloramphenicol resistance transporter protein; major facilitator superfamily protein 3444924..3446189 Actinosynnema mirum DSM 43827 8327168 YP_003100746.1 CDS Amir_2980 NC_013093.1 3446316 3447131 D SMART: helix-turn-helix domain protein; KEGG: rle:RL4049 hypothetical protein; XRE family transcriptional regulator 3446316..3447131 Actinosynnema mirum DSM 43827 8327169 YP_003100747.1 CDS Amir_2981 NC_013093.1 3447220 3448005 D PFAM: protein of unknown function DUF1684; KEGG: acp:A2cp1_0109 protein of unknown function DUF1684; hypothetical protein 3447220..3448005 Actinosynnema mirum DSM 43827 8327170 YP_003100748.1 CDS Amir_2982 NC_013093.1 3448316 3448660 R KEGG: eli:ELI_10905 hypothetical protein; hypothetical protein complement(3448316..3448660) Actinosynnema mirum DSM 43827 8327171 YP_003100749.1 CDS Amir_2983 NC_013093.1 3448844 3450121 D PFAM: extracellular solute-binding protein family 1; KEGG: sugar ABC transporter; family 1 extracellular solute-binding protein 3448844..3450121 Actinosynnema mirum DSM 43827 8327172 YP_003100750.1 CDS Amir_2984 NC_013093.1 3450118 3451035 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sugar ABC transporter; K02025 multiple sugar transport system permease protein; ABC transporter inner membrane protein 3450118..3451035 Actinosynnema mirum DSM 43827 8327173 YP_003100751.1 CDS Amir_2985 NC_013093.1 3451035 3451847 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rec:RHECIAT_PC0000203 sugar ABC transporter, permease protein; ABC transporter inner membrane protein 3451035..3451847 Actinosynnema mirum DSM 43827 8327174 YP_003100752.1 CDS Amir_2986 NC_013093.1 3451844 3454093 D catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI 3451844..3454093 Actinosynnema mirum DSM 43827 8327175 YP_003100753.1 CDS Amir_2987 NC_013093.1 3454204 3455175 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: mmr:Mmar10_0065 ArsR family transcriptional regulator; ArsR family transcriptional regulator complement(3454204..3455175) Actinosynnema mirum DSM 43827 8327176 YP_003100754.1 CDS Amir_2988 NC_013093.1 3455322 3456308 R PFAM: regulatory protein LacI; SMART: regulatory protein LacI; KEGG: bam:Bamb_4929 LacI family transcription regulator; LacI family transcriptional regulator complement(3455322..3456308) Actinosynnema mirum DSM 43827 8327177 YP_003100755.1 CDS Amir_2989 NC_013093.1 3456484 3456630 D hypothetical protein 3456484..3456630 Actinosynnema mirum DSM 43827 8327178 YP_003100756.1 CDS Amir_2990 NC_013093.1 3457371 3459527 D KEGG: bcb:BCB4264_A3230 hypothetical cytosolic protein; hypothetical protein 3457371..3459527 Actinosynnema mirum DSM 43827 8327180 YP_003100757.1 CDS Amir_2991 NC_013093.1 3459797 3460516 D KEGG: dol:Dole_2720 hypothetical protein; hypothetical protein 3459797..3460516 Actinosynnema mirum DSM 43827 8327181 YP_003100758.1 CDS Amir_2992 NC_013093.1 3460625 3461191 D PFAM: helix-turn-helix domain protein; cupin; SMART: helix-turn-helix domain protein; KEGG: transcriptional regulator protein; XRE family transcriptional regulator 3460625..3461191 Actinosynnema mirum DSM 43827 8327182 YP_003100759.1 CDS Amir_2993 NC_013093.1 3461305 3462192 D PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: acp:A2cp1_1436 methyltransferase type 11; type 12 methyltransferase 3461305..3462192 Actinosynnema mirum DSM 43827 8327183 YP_003100760.1 CDS Amir_2994 NC_013093.1 3462234 3462947 D KEGG: hch:HCH_03879 hypothetical protein; hypothetical protein 3462234..3462947 Actinosynnema mirum DSM 43827 8327184 YP_003100761.1 CDS Amir_2995 NC_013093.1 3462954 3463607 D hypothetical protein 3462954..3463607 Actinosynnema mirum DSM 43827 8327185 YP_003100762.1 CDS Amir_2996 NC_013093.1 3463655 3464662 R PFAM: alpha/beta hydrolase fold; KEGG: bcj:BCAM1529 hydrolase; alpha/beta hydrolase fold protein complement(3463655..3464662) Actinosynnema mirum DSM 43827 8327186 YP_003100763.1 CDS Amir_2997 NC_013093.1 3464694 3465161 R PFAM: protein of unknown function DUF664; hypothetical protein complement(3464694..3465161) Actinosynnema mirum DSM 43827 8327187 YP_003100764.1 CDS Amir_2998 NC_013093.1 3465183 3465794 R PFAM: methyltransferase type 11; Tellurite resistance methyltransferase, TehB, core; thiopurine S- methyltransferase; methyltransferase type 12; KEGG: methyltransferase type 12; type 11 methyltransferase complement(3465183..3465794) Actinosynnema mirum DSM 43827 8327188 YP_003100765.1 CDS Amir_2999 NC_013093.1 3465882 3466484 D PFAM: helix-turn-helix domain protein; cupin; SMART: helix-turn-helix domain protein; KEGG: reh:H16_B1998 transcriptional regulator, XRE- family; XRE family transcriptional regulator 3465882..3466484 Actinosynnema mirum DSM 43827 8327189 YP_003100766.1 CDS Amir_3000 NC_013093.1 3466536 3467354 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rso:RSc0215 short chain dehydrogenase; short chain dehydrogenase complement(3466536..3467354) Actinosynnema mirum DSM 43827 8327190 YP_003100767.1 CDS Amir_3001 NC_013093.1 3467421 3468044 D PFAM: regulatory protein TetR; KEGG: afw:Anae109_0884 TetR family transcriptional regulator; TetR family transcriptional regulator 3467421..3468044 Actinosynnema mirum DSM 43827 8327191 YP_003100768.1 CDS Amir_3002 NC_013093.1 3468612 3469730 D PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: tmz:Tmz1t_2342 exonuclease RNase T and DNA polymerase III; exonuclease RNase T and DNA polymerase III 3468612..3469730 Actinosynnema mirum DSM 43827 8327192 YP_003100769.1 CDS Amir_3003 NC_013093.1 3469770 3470789 D PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; KEGG: cja:CJA_2025 MerR-family transcriptional regulator; MerR family transcriptional regulator 3469770..3470789 Actinosynnema mirum DSM 43827 8327193 YP_003100770.1 CDS Amir_3004 NC_013093.1 3470839 3471510 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(3470839..3471510) Actinosynnema mirum DSM 43827 8327194 YP_003100771.1 CDS Amir_3005 NC_013093.1 3471507 3472670 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(3471507..3472670) Actinosynnema mirum DSM 43827 8327195 YP_003100772.1 CDS Amir_3006 NC_013093.1 3472791 3473564 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0970 ABC transporter, ATPase subunit; ABC transporter 3472791..3473564 Actinosynnema mirum DSM 43827 8327196 YP_003100773.1 CDS Amir_3007 NC_013093.1 3473564 3475969 D PFAM: protein of unknown function DUF214; KEGG: aeh:Mlg_1312 hypothetical protein; hypothetical protein 3473564..3475969 Actinosynnema mirum DSM 43827 8327197 YP_003100774.1 CDS Amir_3008 NC_013093.1 3476013 3477188 R PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; PglZ domain protein; KEGG: tbd:Tbd_1468 hypothetical protein; type I phosphodiesterase/nucleotide pyrophosphatase complement(3476013..3477188) Actinosynnema mirum DSM 43827 8327198 YP_003100775.1 CDS Amir_3009 NC_013093.1 3477602 3479269 D PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: lch:Lcho_3323 alpha amylase catalytic region; alpha amylase catalytic subunit 3477602..3479269 Actinosynnema mirum DSM 43827 8327199 YP_003100776.1 CDS Amir_3010 NC_013093.1 3479435 3479821 D KEGG: pag:PLES_32071 hypothetical protein; hypothetical protein 3479435..3479821 Actinosynnema mirum DSM 43827 8327200 YP_003100777.1 CDS Amir_3011 NC_013093.1 3480056 3480805 R PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: afw:Anae109_2808 NADP oxidoreductase coenzyme F420-dependent; NADP oxidoreductase coenzyme F420-dependent complement(3480056..3480805) Actinosynnema mirum DSM 43827 8327201 YP_003100778.1 CDS Amir_3012 NC_013093.1 3480917 3481576 D PFAM: regulatory protein TetR; KEGG: bbt:BBta_0873 TetR family transcriptional regulator; TetR family transcriptional regulator 3480917..3481576 Actinosynnema mirum DSM 43827 8327202 YP_003100779.1 CDS Amir_3013 NC_013093.1 3482195 3482704 D hypothetical protein 3482195..3482704 Actinosynnema mirum DSM 43827 8327203 YP_003100780.1 CDS Amir_3014 NC_013093.1 3483618 3484118 D hypothetical protein 3483618..3484118 Actinosynnema mirum DSM 43827 8327204 YP_003100781.1 CDS Amir_3015 NC_013093.1 3484096 3485427 R PFAM: sodium/calcium exchanger membrane region; KEGG: dvl:Dvul_0633 sodium/calcium exchanger membrane region; sodium/calcium exchanger membrane protein complement(3484096..3485427) Actinosynnema mirum DSM 43827 8327205 YP_003100782.1 CDS Amir_3016 NC_013093.1 3485551 3486378 D PFAM: FAD-binding 9 siderophore-interacting domain protein; siderophore-interacting protein; KEGG: pag:PLES_28941 SIP; FAD-binding 9 siderophore-interacting domain-containing protein 3485551..3486378 Actinosynnema mirum DSM 43827 8327206 YP_003100783.1 CDS Amir_3018 NC_013093.1 3487470 3488300 R TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: phenazine biosynthesis PhzC/PhzF protein; KEGG: acr:Acry_0325 PhzF family phenazine biosynthesis protein; phenazine biosynthesis protein PhzF family complement(3487470..3488300) Actinosynnema mirum DSM 43827 8327208 YP_003100784.1 CDS Amir_3019 NC_013093.1 3488359 3488982 R PFAM: regulatory protein TetR; KEGG: bmu:Bmul_5991 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3488359..3488982) Actinosynnema mirum DSM 43827 8327209 YP_003100785.1 CDS Amir_3020 NC_013093.1 3489110 3489667 D PFAM: NADPH-dependent FMN reductase; NAD(P)H dehydrogenase (quinone); KEGG: rsp:RSP_3069 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 3489110..3489667 Actinosynnema mirum DSM 43827 8327210 YP_003100786.1 CDS Amir_3021 NC_013093.1 3489781 3493725 D PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 3489781..3493725 Actinosynnema mirum DSM 43827 8327211 YP_003100787.1 CDS Amir_3022 NC_013093.1 3493870 3494058 R hypothetical protein complement(3493870..3494058) Actinosynnema mirum DSM 43827 8327212 YP_003100788.1 CDS Amir_3023 NC_013093.1 3494051 3494509 R KEGG: gme:Gmet_1196 PASTA; hypothetical protein complement(3494051..3494509) Actinosynnema mirum DSM 43827 8327213 YP_003100789.1 CDS Amir_3024 NC_013093.1 3494948 3495733 D PFAM: inositol monophosphatase; KEGG: mgm:Mmc1_0078 inositol-phosphate phosphatase; inositol-phosphate phosphatase 3494948..3495733 Actinosynnema mirum DSM 43827 8327214 YP_003100790.1 CDS Amir_3025 NC_013093.1 3495991 3497850 D PFAM: ABC transporter transmembrane protein; ABC transporter; KEGG: mpo:Mpop_2313 lipid A ABC exporter family, fused ATPase and inner membrane subunits; ABC transporter transmembrane protein 3495991..3497850 Actinosynnema mirum DSM 43827 8327215 YP_003100791.1 CDS Amir_3026 NC_013093.1 3497847 3499679 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: maq:Maqu_2187 ABC transporter; ABC transporter 3497847..3499679 Actinosynnema mirum DSM 43827 8327216 YP_003100792.1 CDS Amir_3027 NC_013093.1 3500217 3500906 R PFAM: glycoside hydrolase family 12; KEGG: bja:blr1964 hypothetical protein; hypothetical protein complement(3500217..3500906) Actinosynnema mirum DSM 43827 8327217 YP_003100793.1 CDS Amir_3028 NC_013093.1 3501226 3502983 R KEGG: xcb:XC_4318 avirulence protein; avirulence protein complement(3501226..3502983) Actinosynnema mirum DSM 43827 8327218 YP_003100794.1 CDS Amir_3029 NC_013093.1 3503343 3503639 D KEGG: similar to DNA Helicase; hypothetical protein 3503343..3503639 Actinosynnema mirum DSM 43827 8327219 YP_003100795.1 CDS Amir_3030 NC_013093.1 3503718 3504125 R hypothetical protein complement(3503718..3504125) Actinosynnema mirum DSM 43827 8327220 YP_003100796.1 CDS Amir_3031 NC_013093.1 3504246 3504638 D PFAM: GCN5-related N-acetyltransferase; KEGG: swi:Swit_1410 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 3504246..3504638 Actinosynnema mirum DSM 43827 8327221 YP_003100797.1 CDS Amir_3032 NC_013093.1 3504730 3506376 D KEGG: rsh:Rsph17029_3222 hypothetical protein; kinase-like protein 3504730..3506376 Actinosynnema mirum DSM 43827 8327222 YP_003100798.1 CDS Amir_3033 NC_013093.1 3506376 3509063 D PFAM: endonuclease/exonuclease/phosphatase; phosphoesterase HXTX; DNA polymerase beta domain protein region; KEGG: scl:sce0152 polynucleotide adenyltransferase; endonuclease/exonuclease/phosphatase 3506376..3509063 Actinosynnema mirum DSM 43827 8327223 YP_003100799.1 CDS Amir_3034 NC_013093.1 3509072 3509533 R KEGG: rle:RL3033 hypothetical protein; hypothetical protein complement(3509072..3509533) Actinosynnema mirum DSM 43827 8327224 YP_003100800.1 CDS Amir_3035 NC_013093.1 3509530 3510099 R hypothetical protein complement(3509530..3510099) Actinosynnema mirum DSM 43827 8327225 YP_003100801.1 CDS Amir_3036 NC_013093.1 3510373 3510984 R PFAM: protein of unknown function DUF162; KEGG: eba:ebA3914 hypothetical protein; hypothetical protein complement(3510373..3510984) Actinosynnema mirum DSM 43827 8327226 YP_003100802.1 CDS Amir_3037 NC_013093.1 3511476 3512879 R PFAM: protein of unknown function DUF162; KEGG: rru:Rru_A1412 4Fe-4S ferredoxin, iron-sulfur binding; hypothetical protein complement(3511476..3512879) Actinosynnema mirum DSM 43827 8327227 YP_003100803.1 CDS Amir_3038 NC_013093.1 3512891 3513631 R PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: sus:Acid_5763 hypothetical protein; hypothetical protein complement(3512891..3513631) Actinosynnema mirum DSM 43827 8327228 YP_003100804.1 CDS Amir_3039 NC_013093.1 3513640 3514395 D PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: scl:sce0751 GntR family transcriptional regulator; GntR family transcriptional regulator 3513640..3514395 Actinosynnema mirum DSM 43827 8327229 YP_003100805.1 CDS Amir_3040 NC_013093.1 3514866 3515885 R PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: ppw:PputW619_1959 LacI family transcription regulator; LacI family transcriptional regulator complement(3514866..3515885) Actinosynnema mirum DSM 43827 8327230 YP_003100806.1 CDS Amir_3041 NC_013093.1 3516064 3517566 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bph:Bphy_3463 ABC transporter; ABC transporter 3516064..3517566 Actinosynnema mirum DSM 43827 8327231 YP_003100807.1 CDS Amir_3042 NC_013093.1 3517563 3518585 D PFAM: inner-membrane translocator; KEGG: bac:BamMC406_1213 monosaccharide-transporting ATPase; Monosaccharide-transporting ATPase 3517563..3518585 Actinosynnema mirum DSM 43827 8327232 YP_003100808.1 CDS Amir_3043 NC_013093.1 3518575 3519564 D PFAM: inner-membrane translocator; KEGG: bxe:Bxe_B1037 ABC sugar transporter, inner membrane subunit; Monosaccharide-transporting ATPase 3518575..3519564 Actinosynnema mirum DSM 43827 8327233 YP_003100809.1 CDS Amir_3044 NC_013093.1 3519594 3520670 D TIGRFAM: rhamnose ABC transporter, periplasmic rhamnose-binding protein; KEGG: bph:Bphy_3460 rhamnose ABC transporter, periplasmic rhamnose-binding protein; rhamnose ABC transporter periplasmic rhamnose- binding protein 3519594..3520670 Actinosynnema mirum DSM 43827 8327234 YP_003100810.1 CDS Amir_3045 NC_013093.1 3520733 3521923 D TIGRFAM: L-rhamnose isomerase; PFAM: xylose isomerase; KEGG: acr:Acry_2987 L-rhamnose isomerase; L-rhamnose isomerase 3520733..3521923 Actinosynnema mirum DSM 43827 8327235 YP_003100811.1 CDS Amir_3046 NC_013093.1 3521926 3523956 D TIGRFAM: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; PFAM: class II aldolase/adducin family protein; KR domain protein; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: rde:RD1_3083 short chain dehydrogenase; short chain dehydrogenase 3521926..3523956 Actinosynnema mirum DSM 43827 8327236 YP_003100812.1 CDS Amir_3047 NC_013093.1 3523969 3525375 D PFAM: carbohydrate kinase FGGY; KEGG: sus:Acid_3424 carbohydrate kinase, FGGY; carbohydrate kinase FGGY 3523969..3525375 Actinosynnema mirum DSM 43827 8327237 YP_003100813.1 CDS Amir_3048 NC_013093.1 3525392 3525721 D KEGG: smt:Smal_1180 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 3525392..3525721 Actinosynnema mirum DSM 43827 8327238 YP_003100814.1 CDS Amir_3049 NC_013093.1 3525753 3526997 R PFAM: amidohydrolase; Amidohydrolase 3; KEGG: azc:AZC_1412 hypothetical protein; amidohydrolase complement(3525753..3526997) Actinosynnema mirum DSM 43827 8327239 YP_003100815.1 CDS Amir_3050 NC_013093.1 3527106 3527465 R KEGG: mpo:Mpop_1143 hypothetical protein; hypothetical protein complement(3527106..3527465) Actinosynnema mirum DSM 43827 8327240 YP_003100816.1 CDS Amir_3051 NC_013093.1 3527537 3528394 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: smt:Smal_0276 transcriptional regulator, LysR family; LysR family transcriptional regulator 3527537..3528394 Actinosynnema mirum DSM 43827 8327241 YP_003100817.1 CDS Amir_3054 NC_013093.1 3529055 3530221 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(3529055..3530221) Actinosynnema mirum DSM 43827 8327244 YP_003100818.1 CDS Amir_3055 NC_013093.1 3530167 3530736 R PFAM: regulatory protein TetR; KEGG: mlo:mlr3851 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3530167..3530736) Actinosynnema mirum DSM 43827 8327245 YP_003100819.1 CDS Amir_3056 NC_013093.1 3530770 3532854 R KEGG: hypothetical protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; ECF subfamily RNA polymerase sigma-24 subunit complement(3530770..3532854) Actinosynnema mirum DSM 43827 8327246 YP_003100820.1 CDS Amir_3057 NC_013093.1 3533317 3533655 R KEGG: ses:SARI_03963 hypothetical protein; hypothetical protein complement(3533317..3533655) Actinosynnema mirum DSM 43827 8327247 YP_003100821.1 CDS Amir_3058 NC_013093.1 3533662 3534024 R PFAM: protein of unknown function DUF202; KEGG: pmy:Pmen_1718 hypothetical protein; hypothetical protein complement(3533662..3534024) Actinosynnema mirum DSM 43827 8327248 YP_003100822.1 CDS Amir_3059 NC_013093.1 3534131 3535384 R PFAM: cytochrome P450; KEGG: mlo:mll6125 cytochrome P450-family protein; cytochrome P450 complement(3534131..3535384) Actinosynnema mirum DSM 43827 8327249 YP_003100823.1 CDS Amir_3060 NC_013093.1 3535635 3536576 R SMART: regulatory protein ArsR; KEGG: ade:Adeh_4096 serine/threonine protein kinase; ArsR family transcriptional regulator complement(3535635..3536576) Actinosynnema mirum DSM 43827 8327250 YP_003100824.1 CDS Amir_3061 NC_013093.1 3536831 3537214 D hypothetical protein 3536831..3537214 Actinosynnema mirum DSM 43827 8327251 YP_003100825.1 CDS Amir_3062 NC_013093.1 3537339 3537992 R PFAM: Haem oxygenase-like; KEGG: rpa:RPA1539 heme oxygenase (decyclizing); Heme oxygenase complement(3537339..3537992) Actinosynnema mirum DSM 43827 8327252 YP_003100826.1 CDS Amir_3063 NC_013093.1 3538184 3539098 D PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bha:BH2806 carboxylesterase; alpha/beta hydrolase fold-3 domain-containing protein 3538184..3539098 Actinosynnema mirum DSM 43827 8327253 YP_003100827.1 CDS Amir_3065 NC_013093.1 3540076 3540864 D PFAM: lipolytic protein G-D-S-L family; KEGG: bcb:BCB4264_A2458 hypothetical protein; G-D-S-L family lipolytic protein 3540076..3540864 Actinosynnema mirum DSM 43827 8327255 YP_003100828.1 CDS Amir_3066 NC_013093.1 3540979 3542622 D PFAM: extracellular solute-binding protein family 5; KEGG: dde:Dde_1329 dipeptide ABC transporter, solute-binding protein; family 5 extracellular solute-binding protein 3540979..3542622 Actinosynnema mirum DSM 43827 8327256 YP_003100829.1 CDS Amir_3067 NC_013093.1 3542616 3543728 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dde:Dde_1328 dipeptide ABC transporter, permease protein; ABC transporter inner membrane protein 3542616..3543728 Actinosynnema mirum DSM 43827 8327257 YP_003100830.1 CDS Amir_3068 NC_013093.1 3543725 3544555 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dde:Dde_1327 dipeptide ABC transporter, permease protein; ABC transporter inner membrane protein 3543725..3544555 Actinosynnema mirum DSM 43827 8327258 YP_003100831.1 CDS Amir_3069 NC_013093.1 3544552 3545361 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: dde:Dde_1326 ATPase; ABC transporter 3544552..3545361 Actinosynnema mirum DSM 43827 8327259 YP_003100832.1 CDS Amir_3070 NC_013093.1 3545358 3545996 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: dde:Dde_1325 ATPase; ABC transporter 3545358..3545996 Actinosynnema mirum DSM 43827 8327260 YP_003100833.1 CDS Amir_3071 NC_013093.1 3546155 3547993 D KEGG: scl:sce4939 hypothetical protein; TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; asparagine synthase 3546155..3547993 Actinosynnema mirum DSM 43827 8327261 YP_003100834.1 CDS Amir_3072 NC_013093.1 3548265 3548585 D hypothetical protein 3548265..3548585 Actinosynnema mirum DSM 43827 8327262 YP_003100835.1 CDS Amir_3073 NC_013093.1 3548582 3550843 D KEGG: mgm:Mmc1_2162 hypothetical protein; hypothetical protein 3548582..3550843 Actinosynnema mirum DSM 43827 8327263 YP_003100836.1 CDS Amir_3074 NC_013093.1 3550985 3551314 R PFAM: small multidrug resistance protein; KEGG: acr:Acry_0986 small multidrug resistance protein; small multidrug resistance protein complement(3550985..3551314) Actinosynnema mirum DSM 43827 8327264 YP_003100837.1 CDS Amir_3075 NC_013093.1 3551551 3552864 R PFAM: aminotransferase class-III; KEGG: rsq:Rsph17025_3685 hypothetical protein; class III aminotransferase complement(3551551..3552864) Actinosynnema mirum DSM 43827 8327265 YP_003100838.1 CDS Amir_3076 NC_013093.1 3552861 3554159 R PFAM: aminotransferase class-III; KEGG: aba:Acid345_3989 4-aminobutyrate aminotransferase; acetylornithine transaminase complement(3552861..3554159) Actinosynnema mirum DSM 43827 8327266 YP_003100839.1 CDS Amir_3077 NC_013093.1 3554156 3555721 R PFAM: Aldehyde Dehydrogenase; KEGG: sfu:Sfum_2203 aldehyde dehydrogenase; aldehyde dehydrogenase complement(3554156..3555721) Actinosynnema mirum DSM 43827 8327267 YP_003100840.1 CDS Amir_3078 NC_013093.1 3556274 3558508 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 3556274..3558508 Actinosynnema mirum DSM 43827 8327268 YP_003100841.1 CDS Amir_3079 NC_013093.1 3558964 3560028 D PFAM: O-methyltransferase; KEGG: mxa:MXAN_2296 O-methyltransferase family protein; O-methyltransferase 3558964..3560028 Actinosynnema mirum DSM 43827 8327269 YP_003100842.1 CDS Amir_3080 NC_013093.1 3560165 3561487 D PFAM: beta-lactamase; KEGG: aba:Acid345_4043 beta-lactamase; beta-lactamase 3560165..3561487 Actinosynnema mirum DSM 43827 8327270 YP_003100843.1 CDS Amir_3081 NC_013093.1 3561549 3562364 R hypothetical protein complement(3561549..3562364) Actinosynnema mirum DSM 43827 8327271 YP_003100844.1 CDS Amir_3082 NC_013093.1 3562364 3563494 R KEGG: mex:Mext_2409 hypothetical protein; hypothetical protein complement(3562364..3563494) Actinosynnema mirum DSM 43827 8327272 YP_003100845.1 CDS Amir_3083 NC_013093.1 3563494 3563829 R hypothetical protein complement(3563494..3563829) Actinosynnema mirum DSM 43827 8327273 YP_003100846.1 CDS Amir_3084 NC_013093.1 3563867 3564520 R PFAM: conserved hypothetical protein; KEGG: ade:Adeh_0726 hypothetical protein; hypothetical protein complement(3563867..3564520) Actinosynnema mirum DSM 43827 8327274 YP_003100847.1 CDS Amir_3086 NC_013093.1 3565933 3566313 R KEGG: mrd:Mrad2831_6137 transposase; transposase complement(3565933..3566313) Actinosynnema mirum DSM 43827 8327276 YP_003100848.1 CDS Amir_3087 NC_013093.1 3566472 3566894 R PFAM: endoribonuclease L-PSP; KEGG: mms:mma_1646 hypothetical protein; endoribonuclease L-PSP complement(3566472..3566894) Actinosynnema mirum DSM 43827 8327277 YP_003100849.1 CDS Amir_3088 NC_013093.1 3567005 3567547 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rso:RSc2325 transcription regulator protein; MarR family transcriptional regulator 3567005..3567547 Actinosynnema mirum DSM 43827 8327278 YP_003100850.1 CDS Amir_3089 NC_013093.1 3567656 3569236 D PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 3567656..3569236 Actinosynnema mirum DSM 43827 8327279 YP_003100851.1 CDS Amir_3090 NC_013093.1 3569331 3570182 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpe:KPK_2589 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(3569331..3570182) Actinosynnema mirum DSM 43827 8327280 YP_003100852.1 CDS Amir_3091 NC_013093.1 3570227 3571156 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: hypothetical protein; hypothetical protein 3570227..3571156 Actinosynnema mirum DSM 43827 8327281 YP_003100853.1 CDS Amir_3092 NC_013093.1 3571222 3572085 D SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 3571222..3572085 Actinosynnema mirum DSM 43827 8327282 YP_003100854.1 CDS Amir_3093 NC_013093.1 3572224 3573423 D PFAM: major facilitator superfamily MFS_1; KEGG: bmv:BMASAVP1_A0386 transporter; major facilitator superfamily protein 3572224..3573423 Actinosynnema mirum DSM 43827 8327283 YP_003100855.1 CDS Amir_3095 NC_013093.1 3573679 3573954 R hypothetical protein complement(3573679..3573954) Actinosynnema mirum DSM 43827 8327285 YP_003100856.1 CDS Amir_3096 NC_013093.1 3574068 3574433 D PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: dal:Dalk_3679 transcriptional regulator, ArsR family; ArsR family transcriptional regulator 3574068..3574433 Actinosynnema mirum DSM 43827 8327286 YP_003100857.1 CDS Amir_3097 NC_013093.1 3574437 3576449 D TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: afe:Lferr_0209 heavy metal translocating P- type ATPase; heavy metal translocating P-type ATPase 3574437..3576449 Actinosynnema mirum DSM 43827 8327287 YP_003100858.1 CDS Amir_3098 NC_013093.1 3576475 3577119 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: aba:Acid345_3929 HAD-superfamily hydrolase subfamily IA, variant 3; HAD superfamily hydrolase complement(3576475..3577119) Actinosynnema mirum DSM 43827 8327288 YP_003100859.1 CDS Amir_3099 NC_013093.1 3577184 3578341 D PFAM: ROK family protein; KEGG: sme:SMa2303 ROK family transcriptional regulator; ROK family protein 3577184..3578341 Actinosynnema mirum DSM 43827 8327289 YP_003100860.1 CDS Amir_3100 NC_013093.1 3578325 3579053 R hypothetical protein complement(3578325..3579053) Actinosynnema mirum DSM 43827 8327290 YP_003100861.1 CDS Amir_3101 NC_013093.1 3579050 3580798 R KEGG: ade:Adeh_0992 Vgr-related protein; hypothetical protein complement(3579050..3580798) Actinosynnema mirum DSM 43827 8327291 YP_003100862.1 CDS Amir_3102 NC_013093.1 3580955 3582430 R catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase complement(3580955..3582430) Actinosynnema mirum DSM 43827 8327292 YP_003100863.1 CDS Amir_3103 NC_013093.1 3582456 3583661 R KEGG: bha:BH3300 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase complement(3582456..3583661) Actinosynnema mirum DSM 43827 8327293 YP_003100864.1 CDS Amir_3104 NC_013093.1 3583893 3585032 D KEGG: dal:Dalk_4624 hypothetical protein; hypothetical protein 3583893..3585032 Actinosynnema mirum DSM 43827 8327294 YP_003100865.1 CDS Amir_3105 NC_013093.1 3585039 3585503 R hypothetical protein complement(3585039..3585503) Actinosynnema mirum DSM 43827 8327295 YP_003100866.1 CDS Amir_3106 NC_013093.1 3585645 3587291 R PFAM: Ricin B lectin; glycoside hydrolase clan GH- D; SMART: Ricin B lectin; KEGG: cak:Caul_2129 alpha-galactosidase; Ricin B lectin complement(3585645..3587291) Actinosynnema mirum DSM 43827 8327296 YP_003100867.1 CDS Amir_3107 NC_013093.1 3587729 3590044 D PFAM: protein of unknown function DUF1680; Ricin B lectin; KEGG: hypothetical protein; hypothetical protein 3587729..3590044 Actinosynnema mirum DSM 43827 8327297 YP_003100868.1 CDS Amir_3108 NC_013093.1 3590424 3591530 D PFAM: Ricin B lectin; lipolytic protein G-D-S-L family; SMART: Ricin B lectin; KEGG: hypothetical protein; Ricin B lectin 3590424..3591530 Actinosynnema mirum DSM 43827 8327298 YP_003100869.1 CDS Amir_3109 NC_013093.1 3591766 3593100 D PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: eta:ETA_13590 flavoprotein monooxygenase; FAD-binding monooxygenase 3591766..3593100 Actinosynnema mirum DSM 43827 8327299 YP_003100870.1 CDS Amir_3110 NC_013093.1 3593097 3594698 D PFAM: aminotransferase class I and II; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mxa:MXAN_2571 aminotransferase, class II; class I and II aminotransferase 3593097..3594698 Actinosynnema mirum DSM 43827 8327300 YP_003100871.1 CDS Amir_3111 NC_013093.1 3594753 3595643 R PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: bav:BAV1824 transcriptional regulator; AsnC family transcriptional regulator complement(3594753..3595643) Actinosynnema mirum DSM 43827 8327301 YP_003100872.1 CDS Amir_3112 NC_013093.1 3595640 3596596 R KEGG: similar to ODAG protein; hypothetical protein complement(3595640..3596596) Actinosynnema mirum DSM 43827 8327302 YP_003100873.1 CDS Amir_3113 NC_013093.1 3596668 3598617 R KEGG: xcb:XC_2636 plasmid-related protein; plasmid-like protein complement(3596668..3598617) Actinosynnema mirum DSM 43827 8327303 YP_003100874.1 CDS Amir_3114 NC_013093.1 3598614 3599102 R KEGG: bps:BPSL0769 hypothetical protein; hypothetical protein complement(3598614..3599102) Actinosynnema mirum DSM 43827 8327304 YP_003100875.1 CDS Amir_3115 NC_013093.1 3599099 3600310 R KEGG: xcb:XC_2635 hypothetical protein; hypothetical protein complement(3599099..3600310) Actinosynnema mirum DSM 43827 8327305 YP_003100876.1 CDS Amir_3116 NC_013093.1 3600866 3602050 D hypothetical protein 3600866..3602050 Actinosynnema mirum DSM 43827 8327306 YP_003100877.1 CDS Amir_3117 NC_013093.1 3602172 3602786 R PFAM: regulatory protein TetR; KEGG: dol:Dole_0928 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3602172..3602786) Actinosynnema mirum DSM 43827 8327307 YP_003100878.1 CDS Amir_3118 NC_013093.1 3602876 3603745 D PFAM: NmrA family protein; dTDP-4-dehydrorhamnose reductase; KEGG: mlo:mlr0239 hypothetical protein; NmrA family protein 3602876..3603745 Actinosynnema mirum DSM 43827 8327308 YP_003100879.1 CDS Amir_3119 NC_013093.1 3603742 3604641 D PFAM: luciferase-like monooxygenase; KEGG: swi:Swit_2098 luciferase family protein; luciferase-like monooxygenase 3603742..3604641 Actinosynnema mirum DSM 43827 8327309 YP_003100880.1 CDS Amir_3121 NC_013093.1 3605268 3606515 D PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: xau:Xaut_2796 cyclic nucleotide-binding protein; protein serine/threonine phosphatase 3605268..3606515 Actinosynnema mirum DSM 43827 8327311 YP_003100881.1 CDS Amir_3122 NC_013093.1 3607014 3607250 D hypothetical protein 3607014..3607250 Actinosynnema mirum DSM 43827 8327312 YP_003100882.1 CDS Amir_3123 NC_013093.1 3607447 3611625 D KEGG: mxa:MXAN_5493 WD domain G-beta repeat protein; hypothetical protein 3607447..3611625 Actinosynnema mirum DSM 43827 8327313 YP_003100883.1 CDS Amir_3124 NC_013093.1 3611656 3612777 R KEGG: hne:HNE_0890 TRAP dicarboxylate transporter, DctM subunit; hypothetical protein complement(3611656..3612777) Actinosynnema mirum DSM 43827 8327314 YP_003100884.1 CDS Amir_3125 NC_013093.1 3613022 3613303 R KEGG: mxa:MXAN_6144 oxygen-dependent FAD- linked oxidoreductase; hypothetical protein complement(3613022..3613303) Actinosynnema mirum DSM 43827 8327315 YP_003100885.1 CDS Amir_3126 NC_013093.1 3613444 3613887 R PFAM: FAD linked oxidase domain protein; KEGG: mxa:MXAN_6144 oxygen-dependent FAD- linked oxidoreductase; FAD linked oxidase domain-containing protein complement(3613444..3613887) Actinosynnema mirum DSM 43827 8327316 YP_003100886.1 CDS Amir_3128 NC_013093.1 3614844 3615773 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: scl:sce1114 LysR family transcriptional regulator; LysR family transcriptional regulator complement(3614844..3615773) Actinosynnema mirum DSM 43827 8327318 YP_003100887.1 CDS Amir_3129 NC_013093.1 3615819 3616556 D PFAM: FAD-binding 9 siderophore-interacting domain protein; KEGG: scl:sce8821 hypothetical protein; FAD-binding 9 siderophore-interacting domain-containing protein 3615819..3616556 Actinosynnema mirum DSM 43827 8327319 YP_003100888.1 CDS Amir_3130 NC_013093.1 3616830 3617096 D KEGG: dal:Dalk_3308 acyl carrier protein; hypothetical protein 3616830..3617096 Actinosynnema mirum DSM 43827 8327320 YP_003100889.1 CDS Amir_3131 NC_013093.1 3617096 3618061 D PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier- protein (ACP)] synthase III; KEGG: gdi:GDI3075 3-oxoacyl-[acyl-carrier- protein] synthase 3 (3-oxoacyl [acyl-carrier-protein] synthase III) (beta-ketoacyl-ACP synthase III (KAS III); beta-ketoacyl-acyl-carrier-protein synthase I 3617096..3618061 Actinosynnema mirum DSM 43827 8327321 YP_003100890.1 CDS Amir_3132 NC_013093.1 3618088 3619422 D PFAM: cytochrome P450; KEGG: mxa:MXAN_3943 cytochrome P450 family protein; cytochrome P450 3618088..3619422 Actinosynnema mirum DSM 43827 8327322 YP_003100891.1 CDS Amir_3133 NC_013093.1 3619419 3620462 D PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: bpy:Bphyt_6246 3-oxoacyl-(acyl-carrier- protein (ACP)) synthase III domain protein; 3-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III domain-containing protein 3619419..3620462 Actinosynnema mirum DSM 43827 8327323 YP_003100892.1 CDS Amir_3134 NC_013093.1 3620477 3623104 D PFAM: aminotransferase class-III; protein of unknown function RIO1; aminoglycoside phosphotransferase; ABC-1 domain protein; KEGG: sus:Acid_1674 aminotransferase; class III aminotransferase 3620477..3623104 Actinosynnema mirum DSM 43827 8327324 YP_003100893.1 CDS Amir_3135 NC_013093.1 3623108 3623974 D PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: bur:Bcep18194_C6793 beta-hydroxyacid dehydrogenase; 6-phosphogluconate dehydrogenase 3623108..3623974 Actinosynnema mirum DSM 43827 8327325 YP_003100894.1 CDS Amir_3136 NC_013093.1 3623982 3624347 R KEGG: mpo:Mpop_0225 hypothetical protein; hypothetical protein complement(3623982..3624347) Actinosynnema mirum DSM 43827 8327326 YP_003100895.1 CDS Amir_3137 NC_013093.1 3624401 3625156 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: ret:RHE_PE00158 methyltransferase protein; type 11 methyltransferase complement(3624401..3625156) Actinosynnema mirum DSM 43827 8327327 YP_003100896.1 CDS Amir_3138 NC_013093.1 3625259 3625699 D hypothetical protein 3625259..3625699 Actinosynnema mirum DSM 43827 8327328 YP_003100897.1 CDS Amir_3139 NC_013093.1 3625742 3626476 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: 3-oxoacyl-(acyl-carrier-protein) reductase protein; K00059 3-oxoacyl-; short-chain dehydrogenase/reductase SDR complement(3625742..3626476) Actinosynnema mirum DSM 43827 8327329 YP_003100898.1 CDS Amir_3140 NC_013093.1 3626621 3627313 D PFAM: regulatory protein TetR; KEGG: bid:Bind_1892 TetR family transcriptional regulator; TetR family transcriptional regulator 3626621..3627313 Actinosynnema mirum DSM 43827 8327330 YP_003100899.1 CDS Amir_3141 NC_013093.1 3627477 3628262 D PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: bur:Bcep18194_C6861 fructose-bisphosphate aldolase; deoxyribose-phosphate aldolase/phospho-2-dehydro- 3-deoxyheptonate aldolase 3627477..3628262 Actinosynnema mirum DSM 43827 8327331 YP_003100900.1 CDS Amir_3142 NC_013093.1 3628412 3629452 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: reu:Reut_C6082 zinc-containing alcohol dehydrogenase superfamily protein; alcohol dehydrogenase GroES domain-containing protein complement(3628412..3629452) Actinosynnema mirum DSM 43827 8327332 YP_003100901.1 CDS Amir_3143 NC_013093.1 3629449 3630141 R PFAM: regulatory protein TetR; KEGG: scl:sce6308 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3629449..3630141) Actinosynnema mirum DSM 43827 8327333 YP_003100902.1 CDS Amir_3144 NC_013093.1 3630422 3631927 D PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; KEGG: esa:ESA_00979 hypothetical protein; sulfate transporter 3630422..3631927 Actinosynnema mirum DSM 43827 8327334 YP_003100903.1 CDS Amir_3145 NC_013093.1 3632037 3632759 D PFAM: B3/4 domain protein; KEGG: hypothetical protein; B3/4 domain-containing protein 3632037..3632759 Actinosynnema mirum DSM 43827 8327335 YP_003100904.1 CDS Amir_3146 NC_013093.1 3632947 3634179 D PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 3632947..3634179 Actinosynnema mirum DSM 43827 8327336 YP_003100905.1 CDS Amir_3147 NC_013093.1 3634208 3634759 R PFAM: regulatory protein TetR; KEGG: bat:BAS4873 transcriptional regulator; TetR family transcriptional regulator complement(3634208..3634759) Actinosynnema mirum DSM 43827 8327337 YP_003100906.1 CDS Amir_3148 NC_013093.1 3634832 3635521 R PFAM: ThiJ/PfpI domain protein; KEGG: pfo:Pfl01_1835 ThiJ/PfpI; ThiJ/PfpI domain-containing protein complement(3634832..3635521) Actinosynnema mirum DSM 43827 8327338 YP_003100907.1 CDS Amir_3149 NC_013093.1 3635559 3636392 R PFAM: abortive infection protein; KEGG: sdn:Sden_1909 abortive infection protein; abortive infection protein complement(3635559..3636392) Actinosynnema mirum DSM 43827 8327339 YP_003100908.1 CDS Amir_3151 NC_013093.1 3637126 3638271 R PFAM: arsenical pump membrane protein; Citrate transporter; KEGG: bvi:Bcep1808_6442 arsenical pump membrane protein; arsenical pump membrane protein complement(3637126..3638271) Actinosynnema mirum DSM 43827 8327341 YP_003100909.1 CDS Amir_3152 NC_013093.1 3638268 3639443 R PFAM: metallophosphoesterase; KEGG: rpi:Rpic_2954 metallophosphoesterase; metallophosphoesterase complement(3638268..3639443) Actinosynnema mirum DSM 43827 8327342 YP_003100910.1 CDS Amir_3153 NC_013093.1 3639554 3640222 R PFAM: regulatory protein TetR; KEGG: bid:Bind_0033 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3639554..3640222) Actinosynnema mirum DSM 43827 8327343 YP_003100911.1 CDS Amir_3154 NC_013093.1 3640512 3641660 D PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: sde:Sde_3022 hypothetical protein; Ricin B lectin 3640512..3641660 Actinosynnema mirum DSM 43827 8327344 YP_003100912.1 CDS Amir_3155 NC_013093.1 3641698 3642741 R hypothetical protein complement(3641698..3642741) Actinosynnema mirum DSM 43827 8327345 YP_003100913.1 CDS Amir_3156 NC_013093.1 3642738 3643904 R hypothetical protein complement(3642738..3643904) Actinosynnema mirum DSM 43827 8327346 YP_003100914.1 CDS Amir_3157 NC_013093.1 3644502 3647354 D KEGG: mes:Meso_2703 ribonucleotide-diphosphate reductase subunit alpha; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit; PFAM: ribonucleotide reductase large subunit; ATP- cone domain protein; ribonucleotide reductase large subunit domain protein; ribonucleoside-diphosphate reductase subunit alpha 3644502..3647354 Actinosynnema mirum DSM 43827 8327347 YP_003100915.1 CDS Amir_3158 NC_013093.1 3647351 3648427 D PFAM: ribonucleotide reductase; KEGG: oca:OCAR_6755 ribonucleoside-diphosphate reductase, beta subunit; ribonucleoside-diphosphate reductase 3647351..3648427 Actinosynnema mirum DSM 43827 8327348 YP_003100916.1 CDS Amir_3159 NC_013093.1 3648629 3649867 D TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: bcb:BCB4264_A1874 transport protein, NRAMP family; Mn2+/Fe2+ transporter, NRAMP family 3648629..3649867 Actinosynnema mirum DSM 43827 8327349 YP_003100917.1 CDS Amir_3160 NC_013093.1 3649919 3651133 R PFAM: protein of unknown function DUF955; helix- turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ppd:Ppro_0104 helix-turn-helix domain- containing protein; hypothetical protein complement(3649919..3651133) Actinosynnema mirum DSM 43827 8327350 YP_003100918.1 CDS Amir_3161 NC_013093.1 3651130 3651933 R hypothetical protein complement(3651130..3651933) Actinosynnema mirum DSM 43827 8327351 YP_003100919.1 CDS Amir_3162 NC_013093.1 3652133 3654349 D PFAM: MMPL domain protein; KEGG: bsu:BSU05430 hypothetical protein; MMPL domain-containing protein 3652133..3654349 Actinosynnema mirum DSM 43827 8327352 YP_003100920.1 CDS Amir_3163 NC_013093.1 3654551 3655276 D PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce8862 BKRF1 encodes EBNA-1 protein, latent cycle gene; G-D-S-L family lipolytic protein 3654551..3655276 Actinosynnema mirum DSM 43827 8327353 YP_003100921.1 CDS Amir_3164 NC_013093.1 3655388 3655732 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; anti-sigma-factor antagonist 3655388..3655732 Actinosynnema mirum DSM 43827 8327354 YP_003100922.1 CDS Amir_3165 NC_013093.1 3655954 3656958 D PFAM: Enoyl-CoA hydratase/isomerase; KEGG: acr:Acry_0624 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase 3655954..3656958 Actinosynnema mirum DSM 43827 8327355 YP_003100923.1 CDS Amir_3166 NC_013093.1 3657082 3657708 D KEGG: pzu:PHZ_p0176 hypothetical protein; hypothetical protein 3657082..3657708 Actinosynnema mirum DSM 43827 8327356 YP_003100924.1 CDS Amir_3167 NC_013093.1 3657795 3658148 D hypothetical protein 3657795..3658148 Actinosynnema mirum DSM 43827 8327357 YP_003100925.1 CDS Amir_3168 NC_013093.1 3658171 3658398 R hypothetical protein complement(3658171..3658398) Actinosynnema mirum DSM 43827 8327358 YP_003100926.1 CDS Amir_3169 NC_013093.1 3658614 3659090 D KEGG: kpn:KPN_01215 ABC transporter membrane protein; hypothetical protein 3658614..3659090 Actinosynnema mirum DSM 43827 8327359 YP_003100927.1 CDS Amir_3170 NC_013093.1 3659220 3659933 D KEGG: hypothetical protein; hypothetical protein 3659220..3659933 Actinosynnema mirum DSM 43827 8327360 YP_003100928.1 CDS Amir_3171 NC_013093.1 3660347 3661228 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: msl:Msil_0872 alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain-containing protein complement(3660347..3661228) Actinosynnema mirum DSM 43827 8327361 YP_003100929.1 CDS Amir_3172 NC_013093.1 3661299 3661895 D PFAM: regulatory protein TetR; KEGG: mrd:Mrad2831_4515 TetR family transcriptional regulator; TetR family transcriptional regulator 3661299..3661895 Actinosynnema mirum DSM 43827 8327362 YP_003100930.1 CDS Amir_3173 NC_013093.1 3662147 3662413 D KEGG: mca:MCA1086 hypothetical protein; hypothetical protein 3662147..3662413 Actinosynnema mirum DSM 43827 8327363 YP_003100931.1 CDS Amir_3174 NC_013093.1 3662457 3664709 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: neu:NE0720 ABC transporter permease/ATP- binding protein; ABC transporter 3662457..3664709 Actinosynnema mirum DSM 43827 8327364 YP_003100932.1 CDS Amir_3175 NC_013093.1 3664718 3665968 D PFAM: sodium/hydrogen exchanger; KEGG: mxa:MXAN_0260 cation transporter/universal stress family protein; sodium/hydrogen exchanger 3664718..3665968 Actinosynnema mirum DSM 43827 8327365 YP_003100933.1 CDS Amir_3176 NC_013093.1 3666067 3666642 R KEGG: cak:Caul_0156 ricin B lectin; hypothetical protein complement(3666067..3666642) Actinosynnema mirum DSM 43827 8327366 YP_003100934.1 CDS Amir_3177 NC_013093.1 3666886 3667932 R PFAM: O-methyltransferase; KEGG: mno:Mnod_7639 O-methyltransferase; O-methyltransferase complement(3666886..3667932) Actinosynnema mirum DSM 43827 8327367 YP_003100935.1 CDS Amir_3178 NC_013093.1 3668122 3671346 D PFAM: regulatory protein LuxR; hypothetical protein; Bacterio-opsin activator HTH domain protein; SMART: regulatory protein LuxR; KEGG: GK24882 gene product from transcript GK24882- RA; LuxR family transcriptional regulator 3668122..3671346 Actinosynnema mirum DSM 43827 8327368 YP_003100936.1 CDS Amir_3179 NC_013093.1 3671497 3676278 D PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 3671497..3676278 Actinosynnema mirum DSM 43827 8327369 YP_003100937.1 CDS Amir_3180 NC_013093.1 3676288 3686355 D PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; NAD- dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: met:M446_0170 beta-ketoacyl synthase; acyl transferase 3676288..3686355 Actinosynnema mirum DSM 43827 8327370 YP_003100938.1 CDS Amir_3181 NC_013093.1 3686357 3687136 D PFAM: N-acetyltransferase; KEGG: mxa:MXAN_1194 N-acetyltransferase family protein; N-acetyltransferase 3686357..3687136 Actinosynnema mirum DSM 43827 8327371 YP_003100939.1 CDS Amir_3182 NC_013093.1 3687233 3688174 R TIGRFAM: methyltransferase; PFAM: O-methyltransferase; KEGG: bur:Bcep18194_B1573 protein of unknown function Mtu_121; methyltransferase complement(3687233..3688174) Actinosynnema mirum DSM 43827 8327372 YP_003100940.1 CDS Amir_3183 NC_013093.1 3688171 3689706 R PFAM: monooxygenase FAD-binding; KEGG: gbe:GbCGDNIH1_1787 hypothetical protein; FAD-binding monooxygenase complement(3688171..3689706) Actinosynnema mirum DSM 43827 8327373 YP_003100941.1 CDS Amir_3184 NC_013093.1 3689718 3691043 R PFAM: tryptophan halogenase; monooxygenase FAD- binding; FAD dependent oxidoreductase; KEGG: scl:sce7303 dehyrogenase; tryptophan halogenase complement(3689718..3691043) Actinosynnema mirum DSM 43827 8327374 YP_003100942.1 CDS Amir_3185 NC_013093.1 3691300 3692295 D PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: bid:Bind_3102 3-hydroxybutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase 3691300..3692295 Actinosynnema mirum DSM 43827 8327375 YP_003100943.1 CDS Amir_3186 NC_013093.1 3692292 3692564 D KEGG: gbm:Gbem_0719 hypothetical protein; hypothetical protein 3692292..3692564 Actinosynnema mirum DSM 43827 8327376 YP_003100944.1 CDS Amir_3187 NC_013093.1 3692557 3693672 D PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: hch:HCH_03452 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 3692557..3693672 Actinosynnema mirum DSM 43827 8327377 YP_003100945.1 CDS Amir_3188 NC_013093.1 3693786 3695078 D TIGRFAM: FkbH like protein; HAD-superfamily phosphatase, subfamily IIIC; KEGG: nmu:Nmul_A2515 FkbH domain-containing protein; FkbH like protein 3693786..3695078 Actinosynnema mirum DSM 43827 8327378 YP_003100946.1 CDS Amir_3189 NC_013093.1 3695071 3695733 D PFAM: O-methyltransferase; KEGG: rce:RC1_1081 O-methyltransferase; caffeoyl-CoA O-methyltransferase 3695071..3695733 Actinosynnema mirum DSM 43827 8327379 YP_003100947.1 CDS Amir_3190 NC_013093.1 3695911 3698670 D PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: sme:SMa0464 adenylate/guanylate cyclase; transcriptional regulator 3695911..3698670 Actinosynnema mirum DSM 43827 8327380 YP_003100948.1 CDS Amir_3191 NC_013093.1 3698696 3699832 D PFAM: acyltransferase 3; KEGG: acp:A2cp1_3016 acyltransferase 3; acyltransferase 3 3698696..3699832 Actinosynnema mirum DSM 43827 8327381 YP_003100949.1 CDS Amir_3192 NC_013093.1 3699847 3700194 R PFAM: YCII-related; KEGG: bja:bll6613 hypothetical protein; YCII-like protein complement(3699847..3700194) Actinosynnema mirum DSM 43827 8327382 YP_003100950.1 CDS Amir_3193 NC_013093.1 3700424 3702436 D PFAM: carbamoyltransferase; KEGG: mlo:mlr6171 nodulation protein NolO; carbamoyltransferase 3700424..3702436 Actinosynnema mirum DSM 43827 8327383 YP_003100951.1 CDS Amir_3194 NC_013093.1 3702839 3703204 D hypothetical protein 3702839..3703204 Actinosynnema mirum DSM 43827 8327384 YP_003100952.1 CDS Amir_3195 NC_013093.1 3703523 3703957 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(3703523..3703957) Actinosynnema mirum DSM 43827 8327385 YP_003100953.1 CDS Amir_3196 NC_013093.1 3704178 3705344 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: rpb:RPB_2068 DegT/DnrJ/EryC1/StrS aminotransferase; glutamine--scyllo-inositol transaminase 3704178..3705344 Actinosynnema mirum DSM 43827 8327386 YP_003100954.1 CDS Amir_3197 NC_013093.1 3705533 3719260 D PFAM: acyl transferase; AMP-dependent synthetase and ligase; beta-ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; KEGG: met:M446_0172 beta-ketoacyl synthase; acyl transferase 3705533..3719260 Actinosynnema mirum DSM 43827 8327387 YP_003100955.1 CDS Amir_3198 NC_013093.1 3719257 3728703 D PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase 3719257..3728703 Actinosynnema mirum DSM 43827 8327388 YP_003100956.1 CDS Amir_3199 NC_013093.1 3728780 3729988 D PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; KEGG: cak:Caul_2842 glycosyl transferase family protein; UDP-glucuronosyl/UDP-glucosyltransferase 3728780..3729988 Actinosynnema mirum DSM 43827 8327389 YP_003100957.1 CDS Amir_3200 NC_013093.1 3730371 3731396 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ank:AnaeK_2751 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3730371..3731396 Actinosynnema mirum DSM 43827 8327390 YP_003100958.1 CDS Amir_3201 NC_013093.1 3731475 3731939 R KEGG: sde:Sde_2765 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor complement(3731475..3731939) Actinosynnema mirum DSM 43827 8327391 YP_003100959.1 CDS Amir_3202 NC_013093.1 3732121 3732702 R PFAM: regulatory protein TetR; KEGG: bur:Bcep18194_C6787 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3732121..3732702) Actinosynnema mirum DSM 43827 8327392 YP_003100960.1 CDS Amir_3204 NC_013093.1 3734701 3735750 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 4 domain protein; KEGG: bha:BH1376 RNA polymerase sigma factor RpoD; RpoD subfamily RNA polymerase sigma-70 subunit complement(3734701..3735750) Actinosynnema mirum DSM 43827 8327394 YP_003100961.1 CDS Amir_3205 NC_013093.1 3735915 3736547 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: sil:SPO3211 hypothetical protein; type 11 methyltransferase complement(3735915..3736547) Actinosynnema mirum DSM 43827 8327395 YP_003100962.1 CDS Amir_3207 NC_013093.1 3737416 3737991 R PFAM: bifunctional deaminase-reductase domain protein; KEGG: mxa:MXAN_1250 RibD domain protein; bifunctional deaminase-reductase domain-containing protein complement(3737416..3737991) Actinosynnema mirum DSM 43827 8327397 YP_003100963.1 CDS Amir_3208 NC_013093.1 3738078 3738692 D PFAM: regulatory protein TetR; KEGG: psa:PST_0620 hypothetical protein; TetR family transcriptional regulator 3738078..3738692 Actinosynnema mirum DSM 43827 8327398 YP_003100964.1 CDS Amir_3209 NC_013093.1 3738944 3740629 R KEGG: scl:sce8854 secreted protein; hypothetical protein complement(3738944..3740629) Actinosynnema mirum DSM 43827 8327399 YP_003100965.1 CDS Amir_3211 NC_013093.1 3741439 3742545 R KEGG: rce:RC1_3059 hypothetical protein; hypothetical protein complement(3741439..3742545) Actinosynnema mirum DSM 43827 8327401 YP_003100966.1 CDS Amir_3212 NC_013093.1 3742622 3743374 R PFAM: intradiol ring-cleavage dioxygenase; KEGG: noc:Noc_1128 protocatechuate 3 4-dioxygenase beta subunit like protein; intradiol ring-cleavage dioxygenase complement(3742622..3743374) Actinosynnema mirum DSM 43827 8327402 YP_003100967.1 CDS Amir_3213 NC_013093.1 3743552 3744946 R PFAM: glycoside hydrolase family 43; carbohydrate binding family 6; SMART: cellulose binding type IV; KEGG: hypothetical protein; glycoside hydrolase family protein complement(3743552..3744946) Actinosynnema mirum DSM 43827 8327403 YP_003100968.1 CDS Amir_3214 NC_013093.1 3744954 3746327 R KEGG: XylD; endoxylanase D; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase complement(3744954..3746327) Actinosynnema mirum DSM 43827 8327404 YP_003100969.1 CDS Amir_3215 NC_013093.1 3746657 3747973 D PFAM: glycoside hydrolase family 6; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: mxa:MXAN_4837 endoglucanase; glycoside hydrolase family protein 3746657..3747973 Actinosynnema mirum DSM 43827 8327405 YP_003100970.1 CDS Amir_3216 NC_013093.1 3748226 3750175 D PFAM: glycoside hydrolase family 5; Fibronectin type III domain protein; cellulose-binding family II; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: azc:AZC_1301 endoglucanase; glycoside hydrolase family protein 3748226..3750175 Actinosynnema mirum DSM 43827 8327406 YP_003100971.1 CDS Amir_3217 NC_013093.1 3750230 3750451 R PFAM: proteinase inhibitor I13 potato inhibitor I; KEGG: similar to chymotrypsin inhibitor 2; proteinase inhibitor I13 potato inhibitor I complement(3750230..3750451) Actinosynnema mirum DSM 43827 8327407 YP_003100972.1 CDS Amir_3218 NC_013093.1 3750581 3751756 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3750581..3751756 Actinosynnema mirum DSM 43827 8327408 YP_003100973.1 CDS Amir_3219 NC_013093.1 3751753 3752379 D PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 3751753..3752379 Actinosynnema mirum DSM 43827 8327409 YP_003100974.1 CDS Amir_3220 NC_013093.1 3752670 3753290 D KEGG: pap:PSPA7_2550 hypothetical protein; hypothetical protein 3752670..3753290 Actinosynnema mirum DSM 43827 8327410 YP_003100975.1 CDS Amir_3221 NC_013093.1 3753287 3754132 D KEGG: rde:RD1_3606 hypothetical protein; hypothetical protein 3753287..3754132 Actinosynnema mirum DSM 43827 8327411 YP_003100976.1 CDS Amir_3222 NC_013093.1 3754123 3756144 D PFAM: cellulose-binding family II; Spore coat protein CotH; SMART: cellulose-binding family II; KEGG: scl:sce0771 hypothetical protein; cellulose-binding family protein 3754123..3756144 Actinosynnema mirum DSM 43827 8327412 YP_003100977.1 CDS Amir_3223 NC_013093.1 3756492 3757043 D PFAM: VanZ family protein; VanZ family protein 3756492..3757043 Actinosynnema mirum DSM 43827 8327413 YP_003100978.1 CDS Amir_3224 NC_013093.1 3757040 3758176 D KEGG: hne:HNE_2077 hypothetical protein; hypothetical protein 3757040..3758176 Actinosynnema mirum DSM 43827 8327414 YP_003100979.1 CDS Amir_3225 NC_013093.1 3758191 3758913 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bpy:Bphyt_6660 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(3758191..3758913) Actinosynnema mirum DSM 43827 8327415 YP_003100980.1 CDS Amir_3226 NC_013093.1 3758910 3759947 R PFAM: aldo/keto reductase; KEGG: spe:Spro_1178 aldo/keto reductase; aldo/keto reductase complement(3758910..3759947) Actinosynnema mirum DSM 43827 8327416 YP_003100981.1 CDS Amir_3227 NC_013093.1 3760068 3760901 D SMART: helix-turn-helix domain protein; KEGG: sml:Smlt2229 hypothetical protein; helix-turn-helix domain-containing protein 3760068..3760901 Actinosynnema mirum DSM 43827 8327417 YP_003100982.1 CDS Amir_3228 NC_013093.1 3760957 3763521 R PFAM: Osmosensitive K channel His kinase sensor; ATP-binding region ATPase domain protein; UspA domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mno:Mnod_0197 osmosensitive K+ channel signal transduction histidine kinase; Osmosensitive K channel His kinase sensor complement(3760957..3763521) Actinosynnema mirum DSM 43827 8327418 YP_003100983.1 CDS Amir_3229 NC_013093.1 3763595 3764146 R PFAM: K transporting ATPase KdpC subunit; KEGG: xop:PXO_04385 K+-transporting ATPase, C subunit; Potassium-transporting ATPase complement(3763595..3764146) Actinosynnema mirum DSM 43827 8327419 YP_003100984.1 CDS Amir_3230 NC_013093.1 3764143 3766185 R TIGRFAM: K+-transporting ATPase, B subunit; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: sus:Acid_0074 K+-transporting ATPase, B subunit; K+-transporting ATPase subunit B complement(3764143..3766185) Actinosynnema mirum DSM 43827 8327420 YP_003100985.1 CDS Amir_3231 NC_013093.1 3766182 3767804 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(3766182..3767804) Actinosynnema mirum DSM 43827 8327421 YP_003100986.1 CDS Amir_3232 NC_013093.1 3767804 3767905 R TIGRFAM: K+-transporting ATPase, F subunit; K+-transporting ATPase subunit F complement(3767804..3767905) Actinosynnema mirum DSM 43827 8327422 YP_003100987.1 CDS Amir_3233 NC_013093.1 3768790 3770775 R KEGG: sus:Acid_1791 amino acid transporter; amino acid transporter complement(3768790..3770775) Actinosynnema mirum DSM 43827 8327423 YP_003100988.1 CDS Amir_3234 NC_013093.1 3771068 3772381 D TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: bcy:Bcer98_1141 diaminopimelate decarboxylase; diaminopimelate decarboxylase 3771068..3772381 Actinosynnema mirum DSM 43827 8327424 YP_003100989.1 CDS Amir_3236 NC_013093.1 3772998 3773411 R PFAM: ATP-binding region ATPase domain protein; KEGG: ade:Adeh_0021 periplasmic sensor signal transduction histidine kinase; anti-sigma regulatory factor, serine/threonine protein kinase complement(3772998..3773411) Actinosynnema mirum DSM 43827 8327426 YP_003100990.1 CDS Amir_3237 NC_013093.1 3773780 3774166 R TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sfu:Sfum_4033 anti-sigma-factor antagonist; anti-sigma-factor antagonist complement(3773780..3774166) Actinosynnema mirum DSM 43827 8327427 YP_003100991.1 CDS Amir_3238 NC_013093.1 3774353 3774949 D KEGG: jan:Jann_4076 secreted protein; hypothetical protein 3774353..3774949 Actinosynnema mirum DSM 43827 8327428 YP_003100992.1 CDS Amir_3239 NC_013093.1 3774980 3775990 R PFAM: protein of unknown function DUF218; KEGG: bat:BAS4694 hypothetical protein; hypothetical protein complement(3774980..3775990) Actinosynnema mirum DSM 43827 8327429 YP_003100993.1 CDS Amir_3240 NC_013093.1 3776444 3778192 D PFAM: Recombinase; KEGG: bca:BCE_4599 DNA recombinase; Recombinase 3776444..3778192 Actinosynnema mirum DSM 43827 8327430 YP_003100994.1 CDS Amir_3241 NC_013093.1 3778260 3778451 R hypothetical protein complement(3778260..3778451) Actinosynnema mirum DSM 43827 8327431 YP_003100995.1 CDS Amir_3242 NC_013093.1 3778481 3779083 R hypothetical protein complement(3778481..3779083) Actinosynnema mirum DSM 43827 8327432 YP_003100996.1 CDS Amir_3243 NC_013093.1 3779245 3779502 R hypothetical protein complement(3779245..3779502) Actinosynnema mirum DSM 43827 8327433 YP_003100997.1 CDS Amir_3244 NC_013093.1 3779653 3780615 R PFAM: glycoside hydrolase family 25; peptidoglycan- binding LysM; SMART: peptidoglycan-binding LysM; glycoside hydrolase family 25; KEGG: mxa:MXAN_7387 chitinase, class I; glycoside hydrolase family protein complement(3779653..3780615) Actinosynnema mirum DSM 43827 8327434 YP_003100998.1 CDS Amir_3245 NC_013093.1 3780695 3781039 R KEGG: ade:Adeh_2705 response regulator receiver; hypothetical protein complement(3780695..3781039) Actinosynnema mirum DSM 43827 8327435 YP_003100999.1 CDS Amir_3246 NC_013093.1 3781466 3783685 R KEGG: rso:RS05070 hemagglutinin/hemolysin- related protein; hypothetical protein complement(3781466..3783685) Actinosynnema mirum DSM 43827 8327436 YP_003101000.1 CDS Amir_3247 NC_013093.1 3783672 3784466 R hypothetical protein complement(3783672..3784466) Actinosynnema mirum DSM 43827 8327437 YP_003101001.1 CDS Amir_3248 NC_013093.1 3784471 3785427 R KEGG: bce:BC1906 phage protein; hypothetical protein complement(3784471..3785427) Actinosynnema mirum DSM 43827 8327438 YP_003101002.1 CDS Amir_3249 NC_013093.1 3785424 3787232 R KEGG: rsp:RSP_3854 ICE nucleation protein; hypothetical protein complement(3785424..3787232) Actinosynnema mirum DSM 43827 8327439 YP_003101003.1 CDS Amir_3250 NC_013093.1 3787377 3787706 R hypothetical protein complement(3787377..3787706) Actinosynnema mirum DSM 43827 8327440 YP_003101004.1 CDS Amir_3251 NC_013093.1 3787760 3787987 R hypothetical protein complement(3787760..3787987) Actinosynnema mirum DSM 43827 8327441 YP_003101005.1 CDS Amir_3252 NC_013093.1 3788053 3788676 R hypothetical protein complement(3788053..3788676) Actinosynnema mirum DSM 43827 8327442 YP_003101006.1 CDS Amir_3253 NC_013093.1 3788667 3789116 R hypothetical protein complement(3788667..3789116) Actinosynnema mirum DSM 43827 8327443 YP_003101007.1 CDS Amir_3254 NC_013093.1 3789113 3789433 R hypothetical protein complement(3789113..3789433) Actinosynnema mirum DSM 43827 8327444 YP_003101008.1 CDS Amir_3255 NC_013093.1 3789438 3789743 R hypothetical protein complement(3789438..3789743) Actinosynnema mirum DSM 43827 8327445 YP_003101009.1 CDS Amir_3256 NC_013093.1 3789899 3790264 R hypothetical protein complement(3789899..3790264) Actinosynnema mirum DSM 43827 8327446 YP_003101010.1 CDS Amir_3257 NC_013093.1 3790261 3790446 R hypothetical protein complement(3790261..3790446) Actinosynnema mirum DSM 43827 8327447 YP_003101011.1 CDS Amir_3258 NC_013093.1 3790603 3790800 D hypothetical protein 3790603..3790800 Actinosynnema mirum DSM 43827 8327448 YP_003101012.1 CDS Amir_3259 NC_013093.1 3790809 3791798 R KEGG: bbt:BBta_5785 phage major head protein; hypothetical protein complement(3790809..3791798) Actinosynnema mirum DSM 43827 8327449 YP_003101013.1 CDS Amir_3260 NC_013093.1 3791912 3792271 R hypothetical protein complement(3791912..3792271) Actinosynnema mirum DSM 43827 8327450 YP_003101014.1 CDS Amir_3261 NC_013093.1 3792880 3793845 R KEGG: hypothetical protein; hypothetical protein complement(3792880..3793845) Actinosynnema mirum DSM 43827 8327451 YP_003101015.1 CDS Amir_3262 NC_013093.1 3793851 3795320 R PFAM: protein of unknown function DUF1483; hypothetical protein complement(3793851..3795320) Actinosynnema mirum DSM 43827 8327452 YP_003101016.1 CDS Amir_3263 NC_013093.1 3795474 3796301 D hypothetical protein 3795474..3796301 Actinosynnema mirum DSM 43827 8327453 YP_003101017.1 CDS Amir_3264 NC_013093.1 3796303 3797943 R PFAM: terminase; KEGG: bca:BCE_0397 phage terminase, large subunit; terminase complement(3796303..3797943) Actinosynnema mirum DSM 43827 8327454 YP_003101018.1 CDS Amir_3265 NC_013093.1 3798032 3798493 R TIGRFAM: phage terminase, small subunit, P27 family; PFAM: terminase small subunit P27; KEGG: rsh:Rsph17029_0646 P27 family phage terminase small subunit; phage terminase, small subunit, P27 family complement(3798032..3798493) Actinosynnema mirum DSM 43827 8327455 YP_003101019.1 CDS Amir_3266 NC_013093.1 3798620 3799033 R hypothetical protein complement(3798620..3799033) Actinosynnema mirum DSM 43827 8327456 YP_003101020.1 CDS Amir_3267 NC_013093.1 3799017 3799598 R hypothetical protein complement(3799017..3799598) Actinosynnema mirum DSM 43827 8327457 YP_003101021.1 CDS Amir_3268 NC_013093.1 3799790 3800062 R hypothetical protein complement(3799790..3800062) Actinosynnema mirum DSM 43827 8327458 YP_003101022.1 CDS Amir_3270 NC_013093.1 3800611 3801681 R hypothetical protein complement(3800611..3801681) Actinosynnema mirum DSM 43827 8327460 YP_003101023.1 CDS Amir_3271 NC_013093.1 3801877 3802719 R PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein complement(3801877..3802719) Actinosynnema mirum DSM 43827 8327461 YP_003101024.1 CDS Amir_3272 NC_013093.1 3802797 3803426 D hypothetical protein 3802797..3803426 Actinosynnema mirum DSM 43827 8327462 YP_003101025.1 CDS Amir_3273 NC_013093.1 3803436 3804275 D PFAM: aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 3803436..3804275 Actinosynnema mirum DSM 43827 8327463 YP_003101026.1 CDS Amir_3274 NC_013093.1 3804502 3805287 R PFAM: methyltransferase type 11; Cyclopropane-fatty- acyl-phospholipid synthase; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: hypothetical protein; type 11 methyltransferase complement(3804502..3805287) Actinosynnema mirum DSM 43827 8327464 YP_003101027.1 CDS Amir_3275 NC_013093.1 3805284 3806099 R PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; Cyclopropane-fatty-acyl-phospholipid synthase; methyltransferase type 12; KEGG: hypothetical protein; type 11 methyltransferase complement(3805284..3806099) Actinosynnema mirum DSM 43827 8327465 YP_003101028.1 CDS Amir_3276 NC_013093.1 3806164 3807387 R PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 complement(3806164..3807387) Actinosynnema mirum DSM 43827 8327466 YP_003101029.1 CDS Amir_3277 NC_013093.1 3807416 3808633 R PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 complement(3807416..3808633) Actinosynnema mirum DSM 43827 8327467 YP_003101030.1 CDS Amir_3278 NC_013093.1 3808681 3809337 R PFAM: O-methyltransferase; KEGG: rce:RC1_1081 O-methyltransferase; caffeoyl-CoA O-methyltransferase complement(3808681..3809337) Actinosynnema mirum DSM 43827 8327468 YP_003101031.1 CDS Amir_3279 NC_013093.1 3809590 3810456 D PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: aba:Acid345_4328 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase 3809590..3810456 Actinosynnema mirum DSM 43827 8327469 YP_003101032.1 CDS Amir_3280 NC_013093.1 3810453 3810728 D KEGG: gbm:Gbem_0719 hypothetical protein; hypothetical protein 3810453..3810728 Actinosynnema mirum DSM 43827 8327470 YP_003101033.1 CDS Amir_3281 NC_013093.1 3810725 3811912 D PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: hch:HCH_03452 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 3810725..3811912 Actinosynnema mirum DSM 43827 8327471 YP_003101034.1 CDS Amir_3282 NC_013093.1 3811909 3813000 D TIGRFAM: FkbH like protein; HAD-superfamily phosphatase, subfamily IIIC; KEGG: nmu:Nmul_A2515 FkbH domain-containing protein; FkbH like protein 3811909..3813000 Actinosynnema mirum DSM 43827 8327472 YP_003101035.1 CDS Amir_3283 NC_013093.1 3813054 3815063 D PFAM: carbamoyltransferase; KEGG: mlo:mlr6171 nodulation protein NolO; carbamoyltransferase 3813054..3815063 Actinosynnema mirum DSM 43827 8327473 YP_003101036.1 CDS Amir_3284 NC_013093.1 3815095 3815421 D KEGG: mag:amb2610 O-linked N-acetylglucosamine transferase; O-linked N-acetylglucosamine transferase 3815095..3815421 Actinosynnema mirum DSM 43827 8327474 YP_003101037.1 CDS Amir_3285 NC_013093.1 3815614 3816543 D PFAM: ROK family protein; KEGG: met:M446_2296 ROK family protein; ROK family protein 3815614..3816543 Actinosynnema mirum DSM 43827 8327475 YP_003101038.1 CDS Amir_3286 NC_013093.1 3816501 3816998 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(3816501..3816998) Actinosynnema mirum DSM 43827 8327476 YP_003101039.1 CDS Amir_3287 NC_013093.1 3817176 3818342 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: rpb:RPB_2068 DegT/DnrJ/EryC1/StrS aminotransferase; glutamine--scyllo-inositol transaminase 3817176..3818342 Actinosynnema mirum DSM 43827 8327477 YP_003101040.1 CDS Amir_3288 NC_013093.1 3818416 3819540 D PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; KEGG: rpb:RPB_2066 oxidoreductase-like; oxidoreductase domain-containing protein 3818416..3819540 Actinosynnema mirum DSM 43827 8327478 YP_003101041.1 CDS Amir_3289 NC_013093.1 3819540 3820334 D TIGRFAM: AHBA synthesis associated protein; HAD- superfamily hydrolase, subfamily IA, variant 3; HAD- superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpb:RPB_2065 HAD-superfamily hydrolase; AHBA synthesis associated protein 3819540..3820334 Actinosynnema mirum DSM 43827 8327479 YP_003101042.1 CDS mhpA NC_013093.1 3820381 3821952 R catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase complement(3820381..3821952) Actinosynnema mirum DSM 43827 8327480 YP_003101043.1 CDS Amir_3291 NC_013093.1 3821957 3822733 R PFAM: N-acetyltransferase; KEGG: si:rp71-1f1.6; N-acetyltransferase complement(3821957..3822733) Actinosynnema mirum DSM 43827 8327481 YP_003101044.1 CDS Amir_3292 NC_013093.1 3822742 3834366 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; beta-ketoacyl synthase; acyl transferase; alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; KEGG: met:M446_0172 beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR complement(3822742..3834366) Actinosynnema mirum DSM 43827 8327482 YP_003101045.1 CDS Amir_3293 NC_013093.1 3834374 3844600 R PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase complement(3834374..3844600) Actinosynnema mirum DSM 43827 8327483 YP_003101046.1 CDS Amir_3294 NC_013093.1 3844681 3864987 R PFAM: acyl transferase; AMP-dependent synthetase and ligase; beta-ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I; acyl transferase complement(3844681..3864987) Actinosynnema mirum DSM 43827 8327484 YP_003101047.1 CDS Amir_3295 NC_013093.1 3865365 3866054 D hypothetical protein 3865365..3866054 Actinosynnema mirum DSM 43827 8327485 YP_003101048.1 CDS Amir_3296 NC_013093.1 3866242 3867291 D PFAM: 3-dehydroquinate synthase; KEGG: gsu:GSU2025 3-dehydroquinate synthase; 3-dehydroquinate synthase 3866242..3867291 Actinosynnema mirum DSM 43827 8327486 YP_003101049.1 CDS Amir_3297 NC_013093.1 3867406 3870132 R PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; KEGG: vei:Veis_2932 regulatory protein, LuxR; LuxR family transcriptional regulator complement(3867406..3870132) Actinosynnema mirum DSM 43827 8327487 YP_003101050.1 CDS Amir_3298 NC_013093.1 3871496 3871909 D PFAM: GCN5-related N-acetyltransferase; KEGG: GNAT family acetyltransferase; GCN5-like N-acetyltransferase 3871496..3871909 Actinosynnema mirum DSM 43827 8327488 YP_003101051.1 CDS Amir_3299 NC_013093.1 3871967 3872809 R SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; helix-turn-helix domain-containing protein complement(3871967..3872809) Actinosynnema mirum DSM 43827 8327489 YP_003101052.1 CDS Amir_3300 NC_013093.1 3872966 3873964 D KEGG: aav:Aave_4523 superoxide dismutase; superoxide dismutase 3872966..3873964 Actinosynnema mirum DSM 43827 8327490 YP_003101053.1 CDS Amir_3301 NC_013093.1 3874243 3875700 D PFAM: glycoside hydrolase family 62; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: glycosyl hydrolase family 62 protein; glycoside hydrolase family protein 3874243..3875700 Actinosynnema mirum DSM 43827 8327491 YP_003101054.1 CDS Amir_3302 NC_013093.1 3875783 3877381 D PFAM: glycoside hydrolase family 43; KEGG: xylosidase/glycosyl hydrolase; glycoside hydrolase family protein 3875783..3877381 Actinosynnema mirum DSM 43827 8327492 YP_003101055.1 CDS Amir_3303 NC_013093.1 3877420 3878730 D PFAM: glycoside hydrolase family 62; cellulose- binding family II; SMART: cellulose-binding family II; KEGG: hypothetical protein; glycoside hydrolase family protein 3877420..3878730 Actinosynnema mirum DSM 43827 8327493 YP_003101056.1 CDS Amir_3304 NC_013093.1 3878775 3879851 D PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: bur:Bcep18194_B2373 LacI family transcription regulator; LacI family transcriptional regulator 3878775..3879851 Actinosynnema mirum DSM 43827 8327494 YP_003101057.1 CDS Amir_3305 NC_013093.1 3879900 3881114 R KEGG: mxa:MXAN_1686 acetyltransferase, GNAT family; hypothetical protein complement(3879900..3881114) Actinosynnema mirum DSM 43827 8327495 YP_003101058.1 CDS Amir_3306 NC_013093.1 3881218 3881787 D PFAM: regulatory protein TetR; KEGG: bcy:Bcer98_3256 TetR family transcriptional regulator; TetR family transcriptional regulator 3881218..3881787 Actinosynnema mirum DSM 43827 8327496 YP_003101059.1 CDS Amir_3307 NC_013093.1 3881859 3882383 D PFAM: isochorismatase hydrolase; KEGG: bxe:Bxe_C0259 isochorismatase hydrolase family protein; isochorismatase hydrolase 3881859..3882383 Actinosynnema mirum DSM 43827 8327497 YP_003101060.1 CDS Amir_3308 NC_013093.1 3882421 3885438 R PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: scl:sce5225 protein kinase; transcriptional regulator, winged helix family complement(3882421..3885438) Actinosynnema mirum DSM 43827 8327498 YP_003101061.1 CDS Amir_3309 NC_013093.1 3885560 3886279 D KEGG: scl:sce8587 hypothetical protein; hypothetical protein 3885560..3886279 Actinosynnema mirum DSM 43827 8327499 YP_003101062.1 CDS Amir_3310 NC_013093.1 3886345 3887115 R PFAM: regulatory protein TetR; KEGG: bid:Bind_1892 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3886345..3887115) Actinosynnema mirum DSM 43827 8327500 YP_003101063.1 CDS Amir_3311 NC_013093.1 3887208 3888134 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: short-chain oxidoreductase protein; short-chain dehydrogenase/reductase SDR 3887208..3888134 Actinosynnema mirum DSM 43827 8327501 YP_003101064.1 CDS Amir_3312 NC_013093.1 3888175 3888381 D PFAM: 4-oxalocrotonate tautomerase; KEGG: bcm:Bcenmc03_4438 4-oxalocrotonate tautomerase; 4-oxalocrotonate tautomerase 3888175..3888381 Actinosynnema mirum DSM 43827 8327502 YP_003101065.1 CDS Amir_3313 NC_013093.1 3888426 3888971 R PFAM: bifunctional deaminase-reductase domain protein; KEGG: mes:Meso_4307 bifunctional deaminase- reductase-like; bifunctional deaminase-reductase domain-containing protein complement(3888426..3888971) Actinosynnema mirum DSM 43827 8327503 YP_003101066.1 CDS Amir_3314 NC_013093.1 3889055 3889723 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(3889055..3889723) Actinosynnema mirum DSM 43827 8327504 YP_003101067.1 CDS Amir_3315 NC_013093.1 3889724 3890905 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(3889724..3890905) Actinosynnema mirum DSM 43827 8327505 YP_003101068.1 CDS Amir_3316 NC_013093.1 3891062 3892516 D PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: atu:Atu2171 hydrolase; TAP domain-containing protein 3891062..3892516 Actinosynnema mirum DSM 43827 8327506 YP_003101069.1 CDS Amir_3317 NC_013093.1 3892588 3893877 R KEGG: eli:ELI_05955 beta-lactamase; beta-lactamase class A-like protein complement(3892588..3893877) Actinosynnema mirum DSM 43827 8327507 YP_003101070.1 CDS Amir_3318 NC_013093.1 3893896 3894546 R hypothetical protein complement(3893896..3894546) Actinosynnema mirum DSM 43827 8327508 YP_003101071.1 CDS Amir_3320 NC_013093.1 3895604 3896818 R KEGG: dvm:DvMF_2570 hypothetical protein; hypothetical protein complement(3895604..3896818) Actinosynnema mirum DSM 43827 8327510 YP_003101072.1 CDS Amir_3321 NC_013093.1 3896815 3898071 R PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: dde:Dde_0483 ATPase; ATPase complement(3896815..3898071) Actinosynnema mirum DSM 43827 8327511 YP_003101073.1 CDS Amir_3322 NC_013093.1 3898155 3899558 R KEGG: rsq:Rsph17025_0280 sporulation domain- containing protein; hypothetical protein complement(3898155..3899558) Actinosynnema mirum DSM 43827 8327512 YP_003101074.1 CDS Amir_3323 NC_013093.1 3899723 3900349 R hypothetical protein complement(3899723..3900349) Actinosynnema mirum DSM 43827 8327513 YP_003101075.1 CDS Amir_3324 NC_013093.1 3900346 3901152 R PFAM: regulatory protein MarR; KEGG: scl:sce6114 hypothetical protein; MarR family transcriptional regulator complement(3900346..3901152) Actinosynnema mirum DSM 43827 8327514 YP_003101076.1 CDS Amir_3325 NC_013093.1 3901214 3903346 D PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: sus:Acid_0469 peptidase S9B dipeptidylpeptidase IV subunit; Dipeptidyl-peptidase IV 3901214..3903346 Actinosynnema mirum DSM 43827 8327515 YP_003101077.1 CDS Amir_3326 NC_013093.1 3903655 3904578 D SMART: helix-turn-helix- domain containing protein AraC type; KEGG: aeh:Mlg_1632 AraC family transcriptional regulator; AraC family transcriptional regulator 3903655..3904578 Actinosynnema mirum DSM 43827 8327516 YP_003101078.1 CDS Amir_3327 NC_013093.1 3904689 3906488 D PFAM: asparagine synthase; KEGG: swi:Swit_4548 asparagine synthase; asparagine synthase 3904689..3906488 Actinosynnema mirum DSM 43827 8327517 YP_003101079.1 CDS Amir_3328 NC_013093.1 3906485 3906742 D hypothetical protein 3906485..3906742 Actinosynnema mirum DSM 43827 8327518 YP_003101080.1 CDS Amir_3329 NC_013093.1 3906754 3907152 D KEGG: cak:Caul_5192 hypothetical protein; hypothetical protein 3906754..3907152 Actinosynnema mirum DSM 43827 8327519 YP_003101081.1 CDS Amir_3330 NC_013093.1 3907424 3907735 R hypothetical protein complement(3907424..3907735) Actinosynnema mirum DSM 43827 8327520 YP_003101082.1 CDS Amir_3331 NC_013093.1 3907835 3908881 R PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pfl:PFL_2250 transcriptional activator FtrA; AraC family transcriptional regulator complement(3907835..3908881) Actinosynnema mirum DSM 43827 8327521 YP_003101083.1 CDS Amir_3332 NC_013093.1 3908959 3909351 D PFAM: cupin; KEGG: bja:blr5564 hypothetical protein; cyclic nucleotide-binding protein 3908959..3909351 Actinosynnema mirum DSM 43827 8327522 YP_003101084.1 CDS Amir_3333 NC_013093.1 3909355 3910038 R PFAM: regulatory protein TetR; KEGG: bid:Bind_0033 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3909355..3910038) Actinosynnema mirum DSM 43827 8327523 YP_003101085.1 CDS Amir_3334 NC_013093.1 3910141 3911040 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bid:Bind_0032 short-chain dehydrogenase/reductase SDR; short chain dehydrogenase 3910141..3911040 Actinosynnema mirum DSM 43827 8327524 YP_003101086.1 CDS Amir_3335 NC_013093.1 3911164 3912900 R PFAM: glycoside hydrolase family 5; protein of unknown function DUF291; KEGG: bha:BH0603 endo-beta-1,4-glucanase (celulase B); Cellulase complement(3911164..3912900) Actinosynnema mirum DSM 43827 8327525 YP_003101087.1 CDS Amir_3336 NC_013093.1 3913209 3914822 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH0482 lipoprotein; family 1 extracellular solute-binding protein 3913209..3914822 Actinosynnema mirum DSM 43827 8327526 YP_003101088.1 CDS Amir_3338 NC_013093.1 3915744 3916769 R KEGG: aav:Aave_4199 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(3915744..3916769) Actinosynnema mirum DSM 43827 8327528 YP_003101089.1 CDS Amir_3339 NC_013093.1 3916885 3917724 R PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: scl:sce8968 nucleotide-diphosphate-sugar epimerase; NmrA family protein complement(3916885..3917724) Actinosynnema mirum DSM 43827 8327529 YP_003101090.1 CDS Amir_3340 NC_013093.1 3917823 3918200 D PFAM: helix-turn-helix HxlR type; KEGG: aav:Aave_1296 transcriptional regulator, HxlR family; HxlR family transcriptional regulator 3917823..3918200 Actinosynnema mirum DSM 43827 8327530 YP_003101091.1 CDS Amir_3342 NC_013093.1 3919105 3919569 D hypothetical protein 3919105..3919569 Actinosynnema mirum DSM 43827 8327532 YP_003101092.1 CDS Amir_3344 NC_013093.1 3920479 3921129 R hypothetical protein complement(3920479..3921129) Actinosynnema mirum DSM 43827 8327534 YP_003101093.1 CDS Amir_3345 NC_013093.1 3921150 3921938 D PFAM: alpha/beta hydrolase fold; KEGG: pzu:PHZ_c1878 hypothetical protein; alpha/beta hydrolase fold protein 3921150..3921938 Actinosynnema mirum DSM 43827 8327535 YP_003101094.1 CDS Amir_3346 NC_013093.1 3922119 3922382 D hypothetical protein 3922119..3922382 Actinosynnema mirum DSM 43827 8327536 YP_003101095.1 CDS Amir_3347 NC_013093.1 3922438 3922704 R hypothetical protein complement(3922438..3922704) Actinosynnema mirum DSM 43827 8327537 YP_003101096.1 CDS Amir_3348 NC_013093.1 3922879 3923676 R PFAM: alpha/beta hydrolase fold; KEGG: bat:BAS3592 alpha/beta fold family hydrolase; alpha/beta hydrolase fold protein complement(3922879..3923676) Actinosynnema mirum DSM 43827 8327538 YP_003101097.1 CDS Amir_3349 NC_013093.1 3923830 3924831 D KEGG: sus:Acid_6922 natural resistance-associated macrophage protein; hypothetical protein 3923830..3924831 Actinosynnema mirum DSM 43827 8327539 YP_003101098.1 CDS Amir_3350 NC_013093.1 3925037 3925981 D PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: rso:RS05496 oxidoreductase protein; short-chain dehydrogenase/reductase SDR 3925037..3925981 Actinosynnema mirum DSM 43827 8327540 YP_003101099.1 CDS Amir_3351 NC_013093.1 3926044 3926307 R KEGG: afw:Anae109_3772 hypothetical protein; hypothetical protein complement(3926044..3926307) Actinosynnema mirum DSM 43827 8327541 YP_003101100.1 CDS Amir_3352 NC_013093.1 3926429 3927757 R PFAM: carboxylesterase type B; KEGG: swi:Swit_1148 carboxylesterase, type B; carboxylesterase type B complement(3926429..3927757) Actinosynnema mirum DSM 43827 8327542 YP_003101101.1 CDS Amir_3353 NC_013093.1 3927789 3928787 R PFAM: beta-lactamase domain protein; KEGG: nar:Saro_2457 beta-lactamase-like; beta-lactamase domain-containing protein complement(3927789..3928787) Actinosynnema mirum DSM 43827 8327543 YP_003101102.1 CDS Amir_3354 NC_013093.1 3928866 3929546 R hypothetical protein complement(3928866..3929546) Actinosynnema mirum DSM 43827 8327544 YP_003101103.1 CDS Amir_3355 NC_013093.1 3929878 3930843 R PFAM: TAP domain protein; KEGG: NACA, TEBP; nascent polypeptide-associated complex alpha subunit; TAP domain-containing protein complement(3929878..3930843) Actinosynnema mirum DSM 43827 8327545 YP_003101104.1 CDS Amir_3356 NC_013093.1 3930994 3932274 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 3930994..3932274 Actinosynnema mirum DSM 43827 8327546 YP_003101105.1 CDS Amir_3357 NC_013093.1 3932285 3932944 D PFAM: GCN5-related N-acetyltransferase; KEGG: swi:Swit_3205 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 3932285..3932944 Actinosynnema mirum DSM 43827 8327547 YP_003101106.1 CDS Amir_3358 NC_013093.1 3932954 3934537 R hypothetical protein complement(3932954..3934537) Actinosynnema mirum DSM 43827 8327548 YP_003101107.1 CDS Amir_3359 NC_013093.1 3934640 3935632 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: bid:Bind_1144 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(3934640..3935632) Actinosynnema mirum DSM 43827 8327549 YP_003101108.1 CDS Amir_3360 NC_013093.1 3935634 3936218 R PFAM: regulatory protein TetR; KEGG: scl:sce7471 TetR family transcriptional regulator; TetR family transcriptional regulator complement(3935634..3936218) Actinosynnema mirum DSM 43827 8327550 YP_003101109.1 CDS Amir_3361 NC_013093.1 3936259 3936765 R PFAM: GCN5-related N-acetyltransferase; KEGG: bac:BamMC406_4517 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(3936259..3936765) Actinosynnema mirum DSM 43827 8327551 YP_003101110.1 CDS Amir_3362 NC_013093.1 3937213 3937773 D PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein; bifunctional deaminase-reductase domain-containing protein 3937213..3937773 Actinosynnema mirum DSM 43827 8327552 YP_003101111.1 CDS Amir_3365 NC_013093.1 3938634 3939644 R PFAM: aldo/keto reductase; KEGG: bxe:Bxe_B0085 norsolorinic acid reductase; aldo/keto reductase complement(3938634..3939644) Actinosynnema mirum DSM 43827 8327555 YP_003101112.1 CDS Amir_3366 NC_013093.1 3939750 3940679 D PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bur:Bcep18194_C7080 AraC family transcriptional regulator; AraC family transcriptional regulator 3939750..3940679 Actinosynnema mirum DSM 43827 8327556 YP_003101113.1 CDS Amir_3367 NC_013093.1 3940659 3941189 R hypothetical protein complement(3940659..3941189) Actinosynnema mirum DSM 43827 8327557 YP_003101114.1 CDS Amir_3368 NC_013093.1 3941285 3943633 D PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: mno:Mnod_8717 D-xylulose 5-phosphate/D- fructose 6-phosphate phosphoketolase; phosphoketolase 3941285..3943633 Actinosynnema mirum DSM 43827 8327558 YP_003101115.1 CDS Amir_3369 NC_013093.1 3943630 3944721 D TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: bsu:BSU29470 acetate kinase; acetate kinase 3943630..3944721 Actinosynnema mirum DSM 43827 8327559 YP_003101116.1 CDS Amir_3370 NC_013093.1 3944728 3945393 R hypothetical protein complement(3944728..3945393) Actinosynnema mirum DSM 43827 8327560 YP_003101117.1 CDS Amir_3371 NC_013093.1 3945485 3945910 D PFAM: NUDIX hydrolase; KEGG: oan:Oant_1677 NUDIX hydrolase; NUDIX hydrolase 3945485..3945910 Actinosynnema mirum DSM 43827 8327561 YP_003101118.1 CDS Amir_3372 NC_013093.1 3946003 3946254 D hypothetical protein 3946003..3946254 Actinosynnema mirum DSM 43827 8327562 YP_003101119.1 CDS Amir_3373 NC_013093.1 3946558 3947166 D hypothetical protein 3946558..3947166 Actinosynnema mirum DSM 43827 8327563 YP_003101120.1 CDS Amir_3374 NC_013093.1 3947232 3947450 D KEGG: ccv:CCV52592_2062 hypothetical protein; hypothetical protein 3947232..3947450 Actinosynnema mirum DSM 43827 8327564 YP_003101121.1 CDS Amir_3375 NC_013093.1 3947477 3947797 D hypothetical protein 3947477..3947797 Actinosynnema mirum DSM 43827 8327565 YP_003101122.1 CDS Amir_3376 NC_013093.1 3947820 3949580 R PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: scl:sce2120 pyruvate decarboxylase; thiamine pyrophosphate TPP-binding domain-containing protein complement(3947820..3949580) Actinosynnema mirum DSM 43827 8327566 YP_003101123.1 CDS Amir_3377 NC_013093.1 3949577 3950224 R PFAM: alcohol dehydrogenase GroES domain protein; KEGG: noc:Noc_0592 zinc-containing alcohol dehydrogenase superfamily protein; alcohol dehydrogenase GroES domain-containing protein complement(3949577..3950224) Actinosynnema mirum DSM 43827 8327567 YP_003101124.1 CDS Amir_3378 NC_013093.1 3950401 3951231 R PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; KEGG: spe:Spro_1223 glycoside hydrolase family protein; Fibronectin type III domain-containing protein complement(3950401..3951231) Actinosynnema mirum DSM 43827 8327568 YP_003101125.1 CDS Amir_3379 NC_013093.1 3951338 3952585 R PFAM: major facilitator superfamily MFS_1; KEGG: csa:Csal_3232 major facilitator superfamily MFS_1; major facilitator superfamily protein complement(3951338..3952585) Actinosynnema mirum DSM 43827 8327569 YP_003101126.1 CDS Amir_3380 NC_013093.1 3952653 3953552 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: smt:Smal_0276 transcriptional regulator, LysR family; LysR family transcriptional regulator 3952653..3953552 Actinosynnema mirum DSM 43827 8327570 YP_003101127.1 CDS Amir_3381 NC_013093.1 3953563 3954576 R KEGG: hypothetical protein; hypothetical protein complement(3953563..3954576) Actinosynnema mirum DSM 43827 8327571 YP_003101128.1 CDS Amir_3382 NC_013093.1 3954765 3955766 D PFAM: regulatory protein LacI; SMART: regulatory protein LacI; KEGG: atc:AGR_L_1215 hypothetical protein; LacI family transcriptional regulator 3954765..3955766 Actinosynnema mirum DSM 43827 8327572 YP_003101129.1 CDS Amir_3383 NC_013093.1 3955763 3957355 D KEGG: atu:Atu4253 hypothetical protein; hypothetical protein 3955763..3957355 Actinosynnema mirum DSM 43827 8327573 YP_003101130.1 CDS Amir_3384 NC_013093.1 3957355 3959562 D PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; KEGG: scl:sce2622 N-methylhydantoinase A, beta subunit; hydantoinase/oxoprolinase 3957355..3959562 Actinosynnema mirum DSM 43827 8327574 YP_003101131.1 CDS Amir_3385 NC_013093.1 3959559 3960107 D hypothetical protein 3959559..3960107 Actinosynnema mirum DSM 43827 8327575 YP_003101132.1 CDS Amir_3386 NC_013093.1 3960111 3961382 D PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; Citrate transporter; KEGG: azc:AZC_1182 H+/citrate symporter; TRAP dicarboxylate transporter subunit DctM 3960111..3961382 Actinosynnema mirum DSM 43827 8327576 YP_003101133.1 CDS Amir_3387 NC_013093.1 3961438 3962070 R KEGG: Muc19; mucin 19; hypothetical protein complement(3961438..3962070) Actinosynnema mirum DSM 43827 8327577 YP_003101134.1 CDS Amir_3388 NC_013093.1 3962558 3963139 R PFAM: NAD(P)H dehydrogenase (quinone); NADPH- dependent FMN reductase; KEGG: aav:Aave_3540 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) complement(3962558..3963139) Actinosynnema mirum DSM 43827 8327578 YP_003101135.1 CDS Amir_3389 NC_013093.1 3963237 3963800 D PFAM: regulatory protein TetR; KEGG: bpt:Bpet2251 TetR family transcriptional regulator; TetR family transcriptional regulator 3963237..3963800 Actinosynnema mirum DSM 43827 8327579 YP_003101136.1 CDS Amir_3391 NC_013093.1 3964177 3964728 R PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce1138 acetyltransferase; GCN5-like N-acetyltransferase complement(3964177..3964728) Actinosynnema mirum DSM 43827 8327581 YP_003101137.1 CDS Amir_3392 NC_013093.1 3964803 3965003 R hypothetical protein complement(3964803..3965003) Actinosynnema mirum DSM 43827 8327582 YP_003101138.1 CDS Amir_3394 NC_013093.1 3965998 3968550 D PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; KEGG: acp:A2cp1_1693 protein of unknown function DUF470; hypothetical protein 3965998..3968550 Actinosynnema mirum DSM 43827 8327584 YP_003101139.1 CDS Amir_3395 NC_013093.1 3968568 3969872 D PFAM: esterase; KEGG: bcm:Bcenmc03_5695 esterase; esterase 3968568..3969872 Actinosynnema mirum DSM 43827 8327585 YP_003101140.1 CDS Amir_3396 NC_013093.1 3969917 3970417 R hypothetical protein complement(3969917..3970417) Actinosynnema mirum DSM 43827 8327586 YP_003101141.1 CDS Amir_3397 NC_013093.1 3970759 3972315 D PFAM: Amidohydrolase 3; KEGG: rce:RC1_3136 amidohydrolase family protein; Amidohydrolase 3 3970759..3972315 Actinosynnema mirum DSM 43827 8327587 YP_003101142.1 CDS Amir_3398 NC_013093.1 3972425 3972817 R KEGG: mxa:MXAN_4385 beta-alanyl-CoA:ammonia lyase; beta-alanyl-CoA:ammonia lyase complement(3972425..3972817) Actinosynnema mirum DSM 43827 8327588 YP_003101143.1 CDS Amir_3399 NC_013093.1 3973078 3973431 D PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bcy:Bcer98_1077 regulatory protein GntR HTH; GntR family transcriptional regulator 3973078..3973431 Actinosynnema mirum DSM 43827 8327589 YP_003101144.1 CDS Amir_3400 NC_013093.1 3973462 3974208 D PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: mxa:MXAN_2794 transcriptional regulator, TetR family; TetR family transcriptional regulator 3973462..3974208 Actinosynnema mirum DSM 43827 8327590 YP_003101145.1 CDS Amir_3401 NC_013093.1 3974186 3974374 R PFAM: PspC domain protein; KEGG: xom:XOO_2087 hypothetical protein; phage shock protein PspC complement(3974186..3974374) Actinosynnema mirum DSM 43827 8327591 YP_003101146.1 CDS Amir_3402 NC_013093.1 3974730 3975521 D PFAM: glycosyl transferase family 2; KEGG: ank:AnaeK_2710 glycosyl transferase family 2; family 2 glycosyl transferase 3974730..3975521 Actinosynnema mirum DSM 43827 8327592 YP_003101147.1 CDS Amir_3403 NC_013093.1 3975729 3976073 R hypothetical protein complement(3975729..3976073) Actinosynnema mirum DSM 43827 8327593 YP_003101148.1 CDS Amir_3404 NC_013093.1 3976561 3977085 R PFAM: NUDIX hydrolase; KEGG: nha:Nham_1987 NUDIX hydrolase; NUDIX hydrolase complement(3976561..3977085) Actinosynnema mirum DSM 43827 8327594 YP_003101149.1 CDS Amir_3405 NC_013093.1 3977280 3977507 R hypothetical protein complement(3977280..3977507) Actinosynnema mirum DSM 43827 8327595 YP_003101150.1 CDS Amir_3406 NC_013093.1 3977708 3978679 R KEGG: hypothetical protein; PucR family transcriptional regulator complement(3977708..3978679) Actinosynnema mirum DSM 43827 8327596 YP_003101151.1 CDS Amir_3407 NC_013093.1 3978995 3979573 R PFAM: helix-turn-helix domain protein; cupin; SMART: helix-turn-helix domain protein; KEGG: scl:sce6511 transcriptional regulator; XRE family transcriptional regulator complement(3978995..3979573) Actinosynnema mirum DSM 43827 8327597 YP_003101152.1 CDS Amir_3408 NC_013093.1 3979646 3980365 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(3979646..3980365) Actinosynnema mirum DSM 43827 8327598 YP_003101153.1 CDS Amir_3409 NC_013093.1 3980471 3980785 D PFAM: transcriptional regulator PadR family protein; KEGG: sus:Acid_0652 PadR family transcriptional regulator; PadR family transcriptional regulator 3980471..3980785 Actinosynnema mirum DSM 43827 8327599 YP_003101154.1 CDS Amir_3410 NC_013093.1 3980782 3981567 D KEGG: ret:RHE_CH02708 hypothetical protein; hypothetical protein 3980782..3981567 Actinosynnema mirum DSM 43827 8327600 YP_003101155.1 CDS Amir_3411 NC_013093.1 3981574 3982983 R PFAM: major facilitator superfamily MFS_1; KEGG: pca:Pcar_1854 major facilitator superfamily permease/BtlA-like; major facilitator superfamily protein complement(3981574..3982983) Actinosynnema mirum DSM 43827 8327601 YP_003101156.1 CDS Amir_3412 NC_013093.1 3983048 3983824 R PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: rce:RC1_2887 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase complement(3983048..3983824) Actinosynnema mirum DSM 43827 8327602 YP_003101157.1 CDS Amir_3413 NC_013093.1 3983892 3984353 D KEGG: scl:sce6697 transcriptional regulator; hypothetical protein 3983892..3984353 Actinosynnema mirum DSM 43827 8327603 YP_003101158.1 CDS Amir_3414 NC_013093.1 3984443 3986464 D KEGG: tbd:Tbd_2428 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 3984443..3986464 Actinosynnema mirum DSM 43827 8327604 YP_003101159.1 CDS Amir_3415 NC_013093.1 3986488 3987147 D KEGG: she:Shewmr4_3786 glyoxalase/bleomycin resistance protein/dioxygenase; hypothetical protein 3986488..3987147 Actinosynnema mirum DSM 43827 8327605 YP_003101160.1 CDS Amir_3416 NC_013093.1 3987208 3987663 R PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein complement(3987208..3987663) Actinosynnema mirum DSM 43827 8327606 YP_003101161.1 CDS Amir_3417 NC_013093.1 3987700 3988560 R KEGG: afw:Anae109_1008 Ku family containing protein; TIGRFAM: Ku protein; PFAM: Ku domain protein; SMART: Ku domain protein; Ku domain containing protein complement(3987700..3988560) Actinosynnema mirum DSM 43827 8327607 YP_003101162.1 CDS Amir_3418 NC_013093.1 3988699 3989256 R PFAM: GCN5-related N-acetyltransferase; KEGG: hne:HNE_3215 acetyltransferase; GCN5-like N-acetyltransferase complement(3988699..3989256) Actinosynnema mirum DSM 43827 8327608 YP_003101163.1 CDS Amir_3419 NC_013093.1 3989388 3990209 D hypothetical protein 3989388..3990209 Actinosynnema mirum DSM 43827 8327609 YP_003101164.1 CDS Amir_3420 NC_013093.1 3990255 3990686 D PFAM: protein of unknown function DUF107; KEGG: sfu:Sfum_2309 protein of unknown function DUF107; hypothetical protein 3990255..3990686 Actinosynnema mirum DSM 43827 8327610 YP_003101165.1 CDS Amir_3421 NC_013093.1 3990698 3991906 D PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: bcy:Bcer98_1560 hypothetical protein; hypothetical protein 3990698..3991906 Actinosynnema mirum DSM 43827 8327611 YP_003101166.1 CDS Amir_3422 NC_013093.1 3991957 3992145 R hypothetical protein complement(3991957..3992145) Actinosynnema mirum DSM 43827 8327612 YP_003101167.1 CDS Amir_3423 NC_013093.1 3992168 3992527 D PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: hha:Hhal_1112 regulatory protein, ArsR; ArsR family transcriptional regulator 3992168..3992527 Actinosynnema mirum DSM 43827 8327613 YP_003101168.1 CDS Amir_3424 NC_013093.1 3992524 3993570 D TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: arsenical-resistance protein precursor; K03325 arsenite transporter, ACR3 family; arsenical-resistance protein 3992524..3993570 Actinosynnema mirum DSM 43827 8327614 YP_003101169.1 CDS Amir_3425 NC_013093.1 3993621 3994031 D PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; KEGG: arsenate reductase ArsC; K03741 arsenate reductase; Protein-tyrosine phosphatase, low molecular weight 3993621..3994031 Actinosynnema mirum DSM 43827 8327615 YP_003101170.1 CDS Amir_3426 NC_013093.1 3994103 3995170 D KEGG: bph:Bphy_3936 zinc finger SWIM domain- containing protein; hypothetical protein 3994103..3995170 Actinosynnema mirum DSM 43827 8327616 YP_003101171.1 CDS Amir_3428 NC_013093.1 3995887 3996168 D PFAM: ANTAR domain protein; ANTAR domain-containing protein 3995887..3996168 Actinosynnema mirum DSM 43827 8327618 YP_003101172.1 CDS Amir_3429 NC_013093.1 3996197 3997570 R PFAM: amidase; KEGG: met:M446_0555 amidase; amidase complement(3996197..3997570) Actinosynnema mirum DSM 43827 8327619 YP_003101173.1 CDS Amir_3430 NC_013093.1 3997770 3998660 D KEGG: mag:amb0998 hypothetical protein; hypothetical protein 3997770..3998660 Actinosynnema mirum DSM 43827 8327620 YP_003101174.1 CDS Amir_3431 NC_013093.1 3998861 3999451 D KEGG: ppg:PputGB1_1457 hypothetical protein; hypothetical protein 3998861..3999451 Actinosynnema mirum DSM 43827 8327621 YP_003101175.1 CDS Amir_3432 NC_013093.1 3999559 4000083 R PFAM: protein of unknown function DUF1470; KEGG: jan:Jann_2411 hypothetical protein; hypothetical protein complement(3999559..4000083) Actinosynnema mirum DSM 43827 8327622 YP_003101176.1 CDS Amir_3433 NC_013093.1 4000098 4000286 D hypothetical protein 4000098..4000286 Actinosynnema mirum DSM 43827 8327623 YP_003101177.1 CDS Amir_3434 NC_013093.1 4000299 4000964 D PFAM: regulatory protein TetR; KEGG: ade:Adeh_2880 TetR family transcriptional regulator; TetR family transcriptional regulator 4000299..4000964 Actinosynnema mirum DSM 43827 8327624 YP_003101178.1 CDS Amir_3435 NC_013093.1 4001187 4001552 R hypothetical protein complement(4001187..4001552) Actinosynnema mirum DSM 43827 8327625 YP_003101179.1 CDS Amir_3436 NC_013093.1 4001870 4002547 D KEGG: hypothetical protein; hypothetical protein 4001870..4002547 Actinosynnema mirum DSM 43827 8327626 YP_003101180.1 CDS Amir_3437 NC_013093.1 4002535 4003248 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: azc:AZC_4194 dehydrogenases; short-chain dehydrogenase/reductase SDR 4002535..4003248 Actinosynnema mirum DSM 43827 8327627 YP_003101181.1 CDS Amir_3438 NC_013093.1 4003208 4004002 R TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: ank:AnaeK_1955 methionine aminopeptidase, type I; methionine aminopeptidase, type I complement(4003208..4004002) Actinosynnema mirum DSM 43827 8327628 YP_003101182.1 CDS Amir_3439 NC_013093.1 4004049 4004309 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: mxa:MXAN_2709 transcriptional regulator; XRE family transcriptional regulator 4004049..4004309 Actinosynnema mirum DSM 43827 8327629 YP_003101183.1 CDS Amir_3440 NC_013093.1 4004327 4005337 R PFAM: Helix-turn-helix type 11 domain protein; regulatory protein DeoR; protein of unknown function UPF0074; SMART: regulatory protein DeoR; KEGG: scl:sce5223 DeoR family transcriptional regulator; Helix-turn-helix type 11 domain-containing protein complement(4004327..4005337) Actinosynnema mirum DSM 43827 8327630 YP_003101184.1 CDS Amir_3441 NC_013093.1 4005370 4006656 D PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: bbt:BBta_2587 monoxygenase; FAD-binding monooxygenase 4005370..4006656 Actinosynnema mirum DSM 43827 8327631 YP_003101185.1 CDS Amir_3442 NC_013093.1 4006769 4007518 R PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: kpe:KPK_3034 transcriptional regulator, DeoR family; DeoR family transcriptional regulator complement(4006769..4007518) Actinosynnema mirum DSM 43827 8327632 YP_003101186.1 CDS Amir_3443 NC_013093.1 4007579 4009156 D PFAM: NUDIX hydrolase; KEGG: hypothetical protein LOC100149318; NUDIX hydrolase 4007579..4009156 Actinosynnema mirum DSM 43827 8327633 YP_003101187.1 CDS Amir_3444 NC_013093.1 4009128 4009751 R hypothetical protein complement(4009128..4009751) Actinosynnema mirum DSM 43827 8327634 YP_003101188.1 CDS Amir_3445 NC_013093.1 4009778 4010566 R PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: scl:sce7572 DNA polymerase III, epsilon subunit; exonuclease RNase T and DNA polymerase III complement(4009778..4010566) Actinosynnema mirum DSM 43827 8327635 YP_003101189.1 CDS Amir_3446 NC_013093.1 4010670 4010912 R hypothetical protein complement(4010670..4010912) Actinosynnema mirum DSM 43827 8327636 YP_003101190.1 CDS Amir_3447 NC_013093.1 4011959 4012933 D PFAM: integrase family protein; KEGG: mag:amb4250 site-specific tyrosine recombinase XerC; integrase family protein 4011959..4012933 Actinosynnema mirum DSM 43827 8327637 YP_003101191.1 CDS Amir_3448 NC_013093.1 4013029 4013874 D SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce1871 AraC family transcriptional regulator; AraC family transcriptional regulator 4013029..4013874 Actinosynnema mirum DSM 43827 8327638 YP_003101192.1 CDS Amir_3449 NC_013093.1 4013941 4014522 D KEGG: cvi:CV_3295 hypothetical protein; hypothetical protein 4013941..4014522 Actinosynnema mirum DSM 43827 8327639 YP_003101193.1 CDS Amir_3450 NC_013093.1 4014596 4015054 R hypothetical protein complement(4014596..4015054) Actinosynnema mirum DSM 43827 8327640 YP_003101194.1 CDS Amir_3451 NC_013093.1 4015301 4016104 R hypothetical protein complement(4015301..4016104) Actinosynnema mirum DSM 43827 8327641 YP_003101195.1 CDS Amir_3452 NC_013093.1 4016110 4016676 R hypothetical protein complement(4016110..4016676) Actinosynnema mirum DSM 43827 8327642 YP_003101196.1 CDS Amir_3453 NC_013093.1 4016788 4018710 D PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: msl:Msil_1579 peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9 prolyl oligopeptidase active site domain-containing protein 4016788..4018710 Actinosynnema mirum DSM 43827 8327643 YP_003101197.1 CDS Amir_3454 NC_013093.1 4018707 4019609 D PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: dal:Dalk_3806 peptidase U61 LD- carboxypeptidase A; peptidase U61 LD-carboxypeptidase A 4018707..4019609 Actinosynnema mirum DSM 43827 8327644 YP_003101198.1 CDS Amir_3455 NC_013093.1 4019625 4019768 D hypothetical protein 4019625..4019768 Actinosynnema mirum DSM 43827 8327645 YP_003101199.1 CDS Amir_3456 NC_013093.1 4019738 4020271 R hypothetical protein complement(4019738..4020271) Actinosynnema mirum DSM 43827 8327646 YP_003101200.1 CDS Amir_3459 NC_013093.1 4022261 4022911 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hypothetical protein; HAD superfamily hydrolase 4022261..4022911 Actinosynnema mirum DSM 43827 8327649 YP_003101201.1 CDS Amir_3460 NC_013093.1 4022908 4023942 D PFAM: aminoglycoside phosphotransferase; KEGG: mrd:Mrad2831_1820 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 4022908..4023942 Actinosynnema mirum DSM 43827 8327650 YP_003101202.1 CDS Amir_3461 NC_013093.1 4023942 4025150 D PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: pen:PSEEN3343 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 4023942..4025150 Actinosynnema mirum DSM 43827 8327651 YP_003101203.1 CDS Amir_3463 NC_013093.1 4025872 4027512 R PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: cti:RALTA_B1385 dipeptide ABC transporter atp_binding domain; ABC transporter complement(4025872..4027512) Actinosynnema mirum DSM 43827 8327653 YP_003101204.1 CDS Amir_3464 NC_013093.1 4027509 4028390 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr6084 ABC transporter, permease; ABC transporter inner membrane protein complement(4027509..4028390) Actinosynnema mirum DSM 43827 8327654 YP_003101205.1 CDS Amir_3465 NC_013093.1 4028387 4029346 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr6083 ABC transporter, permease; ABC transporter inner membrane protein complement(4028387..4029346) Actinosynnema mirum DSM 43827 8327655 YP_003101206.1 CDS Amir_3466 NC_013093.1 4029343 4031133 R PFAM: extracellular solute-binding protein family 5; KEGG: mlo:mlr6082 ABC transporter, binding protein component; family 5 extracellular solute-binding protein complement(4029343..4031133) Actinosynnema mirum DSM 43827 8327656 YP_003101207.1 CDS Amir_3467 NC_013093.1 4031227 4032054 D PFAM: peptidase M55 D-aminopeptidase; KEGG: mrd:Mrad2831_3239 peptidase M55 D- aminopeptidase; peptidase M55 D-aminopeptidase 4031227..4032054 Actinosynnema mirum DSM 43827 8327657 YP_003101208.1 CDS Amir_3468 NC_013093.1 4032060 4033346 D PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: dal:Dalk_4445 peptidase M20; hypothetical protein 4032060..4033346 Actinosynnema mirum DSM 43827 8327658 YP_003101209.1 CDS Amir_3469 NC_013093.1 4033460 4034665 D hypothetical protein 4033460..4034665 Actinosynnema mirum DSM 43827 8327659 YP_003101210.1 CDS Amir_3470 NC_013093.1 4034802 4035797 D KEGG: sml:Smlt2568 LacI-family transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 4034802..4035797 Actinosynnema mirum DSM 43827 8327660 YP_003101211.1 CDS Amir_3471 NC_013093.1 4035802 4036626 D KEGG: scl:sce1247 hypothetical protein; hypothetical protein 4035802..4036626 Actinosynnema mirum DSM 43827 8327661 YP_003101212.1 CDS Amir_3472 NC_013093.1 4036682 4037923 D PFAM: extracellular solute-binding protein family 1; KEGG: bur:Bcep18194_C6933 ABC sugar transporter, periplasmic ligand binding protein; family 1 extracellular solute-binding protein 4036682..4037923 Actinosynnema mirum DSM 43827 8327662 YP_003101213.1 CDS Amir_3473 NC_013093.1 4037927 4038796 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bur:Bcep18194_C6934 ABC sugar transporter, inner membrane subunit; ABC transporter inner membrane protein 4037927..4038796 Actinosynnema mirum DSM 43827 8327663 YP_003101214.1 CDS Amir_3474 NC_013093.1 4038790 4039632 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bur:Bcep18194_C6935 ABC sugar transporter, inner membrane subunit; ABC transporter inner membrane protein 4038790..4039632 Actinosynnema mirum DSM 43827 8327664 YP_003101215.1 CDS Amir_3475 NC_013093.1 4039808 4041025 R PFAM: integrase family protein; KEGG: gme:Gmet_1427 tyrosine recombinase XerD subunit; integrase family protein complement(4039808..4041025) Actinosynnema mirum DSM 43827 8327665 YP_003101216.1 CDS Amir_3476 NC_013093.1 4041194 4042273 D KEGG: hypothetical protein; hypothetical protein 4041194..4042273 Actinosynnema mirum DSM 43827 8327666 YP_003101217.1 CDS Amir_3477 NC_013093.1 4042404 4044617 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: scl:sce3873 WD repeat-containing protein; XRE family transcriptional regulator complement(4042404..4044617) Actinosynnema mirum DSM 43827 8327667 YP_003101218.1 CDS Amir_3478 NC_013093.1 4044754 4045824 D PFAM: esterase; KEGG: mxa:MXAN_4935 esterase; esterase 4044754..4045824 Actinosynnema mirum DSM 43827 8327668 YP_003101219.1 CDS Amir_3479 NC_013093.1 4045880 4047280 R KEGG: bcj:BCAS0321a hypothetical protein; hypothetical protein complement(4045880..4047280) Actinosynnema mirum DSM 43827 8327669 YP_003101220.1 CDS Amir_3480 NC_013093.1 4047277 4047582 R hypothetical protein complement(4047277..4047582) Actinosynnema mirum DSM 43827 8327670 YP_003101221.1 CDS Amir_3481 NC_013093.1 4047579 4047977 R hypothetical protein complement(4047579..4047977) Actinosynnema mirum DSM 43827 8327671 YP_003101222.1 CDS Amir_3482 NC_013093.1 4047974 4048744 R KEGG: pzu:PHZ_c2693 cytochrome C-type biogenesis protein CycH; cytochrome C biogenesis protein CycH complement(4047974..4048744) Actinosynnema mirum DSM 43827 8327672 YP_003101223.1 CDS Amir_3483 NC_013093.1 4048741 4049082 R hypothetical protein complement(4048741..4049082) Actinosynnema mirum DSM 43827 8327673 YP_003101224.1 CDS Amir_3484 NC_013093.1 4049079 4050230 R KEGG: scl:sce3028 protein kinase; hypothetical protein complement(4049079..4050230) Actinosynnema mirum DSM 43827 8327674 YP_003101225.1 CDS Amir_3485 NC_013093.1 4050544 4051353 D KEGG: pau:PA14_07050 hypothetical protein; hypothetical protein 4050544..4051353 Actinosynnema mirum DSM 43827 8327675 YP_003101226.1 CDS Amir_3486 NC_013093.1 4051350 4052294 R PFAM: Helix-turn-helix type 11 domain protein; KEGG: scl:sce5223 DeoR family transcriptional regulator; Helix-turn-helix type 11 domain-containing protein complement(4051350..4052294) Actinosynnema mirum DSM 43827 8327676 YP_003101227.1 CDS Amir_3487 NC_013093.1 4052376 4053401 D PFAM: aldo/keto reductase; KEGG: rle:RL2983 aldo/keto reductase; aldo/keto reductase 4052376..4053401 Actinosynnema mirum DSM 43827 8327677 YP_003101228.1 CDS Amir_3488 NC_013093.1 4053409 4054476 D KEGG: afw:Anae109_3510 hypothetical protein; hypothetical protein 4053409..4054476 Actinosynnema mirum DSM 43827 8327678 YP_003101229.1 CDS Amir_3489 NC_013093.1 4054712 4055314 R PFAM: regulatory protein TetR; KEGG: gdi:GDI2777 transcription regulator; TetR family transcriptional regulator complement(4054712..4055314) Actinosynnema mirum DSM 43827 8327679 YP_003101230.1 CDS Amir_3490 NC_013093.1 4055365 4056312 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bid:Bind_1477 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 4055365..4056312 Actinosynnema mirum DSM 43827 8327680 YP_003101231.1 CDS Amir_3491 NC_013093.1 4056605 4056979 R hypothetical protein complement(4056605..4056979) Actinosynnema mirum DSM 43827 8327681 YP_003101232.1 CDS Amir_3492 NC_013093.1 4057238 4057711 D PFAM: NUDIX hydrolase; KEGG: bba:Bd2755 ATP/GTP-binding protein; NUDIX hydrolase 4057238..4057711 Actinosynnema mirum DSM 43827 8327682 YP_003101233.1 CDS Amir_3493 NC_013093.1 4057749 4058150 R PFAM: endoribonuclease L-PSP; KEGG: mch:Mchl_5535 endoribonuclease L-PSP; endoribonuclease L-PSP complement(4057749..4058150) Actinosynnema mirum DSM 43827 8327683 YP_003101234.1 CDS Amir_3494 NC_013093.1 4058258 4059292 D PFAM: Helix-turn-helix type 11 domain protein; KEGG: mxa:MXAN_2553 hypothetical protein; Helix-turn-helix type 11 domain-containing protein 4058258..4059292 Actinosynnema mirum DSM 43827 8327684 YP_003101235.1 CDS Amir_3495 NC_013093.1 4059367 4060854 D PFAM: cellulose-binding family II; lipolytic protein G-D-S-L family; SMART: cellulose-binding family II; KEGG: ccs:CCNA_02538 endoglucanase E; cellulose-binding family protein 4059367..4060854 Actinosynnema mirum DSM 43827 8327685 YP_003101236.1 CDS Amir_3496 NC_013093.1 4061059 4061430 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: hha:Hhal_0914 transcriptional regulator, MerR family; MerR family transcriptional regulator complement(4061059..4061430) Actinosynnema mirum DSM 43827 8327686 YP_003101237.1 CDS Amir_3497 NC_013093.1 4062172 4062855 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: bcj:BCAM0093 MerR family regulatory protein; MerR family transcriptional regulator complement(4062172..4062855) Actinosynnema mirum DSM 43827 8327687 YP_003101238.1 CDS Amir_3498 NC_013093.1 4062978 4064102 D PFAM: erythromycin esterase; KEGG: swi:Swit_1817 erythromycin esterase; erythromycin esterase 4062978..4064102 Actinosynnema mirum DSM 43827 8327688 YP_003101239.1 CDS Amir_3499 NC_013093.1 4064164 4064673 R hypothetical protein complement(4064164..4064673) Actinosynnema mirum DSM 43827 8327689 YP_003101240.1 CDS Amir_3500 NC_013093.1 4064808 4065212 R KEGG: aeh:Mlg_0162 hypothetical protein; hypothetical protein complement(4064808..4065212) Actinosynnema mirum DSM 43827 8327690 YP_003101241.1 CDS Amir_3501 NC_013093.1 4065312 4066679 D PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: scl:sce2734 ubiquinone/menaquinone biosynthesis methyltransferase UbiE; type 12 methyltransferase 4065312..4066679 Actinosynnema mirum DSM 43827 8327691 YP_003101242.1 CDS Amir_3502 NC_013093.1 4066679 4069183 D PFAM: metallophosphoesterase; KEGG: scl:sce2733 bis(5'-nucleosyl)- tetraphosphatase (symmetrical); metallophosphoesterase 4066679..4069183 Actinosynnema mirum DSM 43827 8327692 YP_003101243.1 CDS Amir_3503 NC_013093.1 4069250 4069828 D PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: scl:sce2276 hypothetical protein; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 4069250..4069828 Actinosynnema mirum DSM 43827 8327693 YP_003101244.1 CDS Amir_3504 NC_013093.1 4069869 4071416 R PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: scl:sce4973 monooxygenase; FAD-binding monooxygenase complement(4069869..4071416) Actinosynnema mirum DSM 43827 8327694 YP_003101245.1 CDS Amir_3505 NC_013093.1 4071577 4072098 D PFAM: conserved hypothetical protein; KEGG: dac:Daci_5761 hypothetical protein; hypothetical protein 4071577..4072098 Actinosynnema mirum DSM 43827 8327695 YP_003101246.1 CDS Amir_3506 NC_013093.1 4072095 4072832 R PFAM: metallophosphoesterase; KEGG: azc:AZC_0786 ICC protein; metallophosphoesterase complement(4072095..4072832) Actinosynnema mirum DSM 43827 8327696 YP_003101247.1 CDS Amir_3507 NC_013093.1 4072942 4074201 D KEGG: hypothetical protein; hypothetical protein 4072942..4074201 Actinosynnema mirum DSM 43827 8327697 YP_003101248.1 CDS Amir_3508 NC_013093.1 4074198 4075157 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: bcy:Bcer98_0541 extracellular solute-binding protein; family 3 extracellular solute-binding protein 4074198..4075157 Actinosynnema mirum DSM 43827 8327698 YP_003101249.1 CDS Amir_3509 NC_013093.1 4075249 4078284 D PFAM: tyrosine protein kinase; SMART: serine/threonine protein kinase; KEGG: scl:sce1432 protein kinase; serine/threonine protein kinase 4075249..4078284 Actinosynnema mirum DSM 43827 8327699 YP_003101250.1 CDS Amir_3510 NC_013093.1 4078281 4079252 D PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: xau:Xaut_0996 protein phosphatase 2C-like protein; protein serine/threonine phosphatase 4078281..4079252 Actinosynnema mirum DSM 43827 8327700 YP_003101251.1 CDS Amir_3511 NC_013093.1 4079400 4079885 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: cti:RALTA_A0035 transcriptional regulator, MarR family; MarR family transcriptional regulator 4079400..4079885 Actinosynnema mirum DSM 43827 8327701 YP_003101252.1 CDS Amir_3512 NC_013093.1 4080150 4081301 D KEGG: rpt:Rpal_0425 cytochrome P450; cytochrome P450-like protein 4080150..4081301 Actinosynnema mirum DSM 43827 8327702 YP_003101253.1 CDS Amir_3515 NC_013093.1 4082150 4083100 R PFAM: aminoglycoside phosphotransferase; aminoglycoside phosphotransferase complement(4082150..4083100) Actinosynnema mirum DSM 43827 8327705 YP_003101254.1 CDS Amir_3516 NC_013093.1 4083149 4084171 R PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pla:Plav_0381 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein complement(4083149..4084171) Actinosynnema mirum DSM 43827 8327706 YP_003101255.1 CDS Amir_3517 NC_013093.1 4084280 4085197 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mpt:Mpe_A3662 AraC family transcriptional regulator; AraC family transcriptional regulator complement(4084280..4085197) Actinosynnema mirum DSM 43827 8327707 YP_003101256.1 CDS Amir_3518 NC_013093.1 4085194 4089114 R KEGG: ses:SARI_01345 ATP-dependent RNA helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; protein of unknown function DUF1605; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; ATPase AAA; ATP-dependent helicase HrpA complement(4085194..4089114) Actinosynnema mirum DSM 43827 8327708 YP_003101257.1 CDS Amir_3519 NC_013093.1 4089281 4090030 R KEGG: cvi:CV_0390 hypothetical protein; hypothetical protein complement(4089281..4090030) Actinosynnema mirum DSM 43827 8327709 YP_003101258.1 CDS Amir_3520 NC_013093.1 4090116 4090481 D PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bja:blr4238 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase 4090116..4090481 Actinosynnema mirum DSM 43827 8327710 YP_003101259.1 CDS Amir_3521 NC_013093.1 4090920 4091606 R PFAM: phosphoglycerate mutase; KEGG: met:M446_2115 phosphoglycerate mutase; phosphoglycerate mutase complement(4090920..4091606) Actinosynnema mirum DSM 43827 8327711 YP_003101260.1 CDS Amir_3522 NC_013093.1 4091743 4092567 R KEGG: atc:AGR_C_1833 undecaprenyl-diphosphatase; TIGRFAM: undecaprenol kinase; PFAM: Bacitracin resistance protein BacA; undecaprenol kinase complement(4091743..4092567) Actinosynnema mirum DSM 43827 8327712 YP_003101261.1 CDS Amir_3523 NC_013093.1 4092564 4093613 R PFAM: luciferase-like monooxygenase; KEGG: pzu:PHZ_c2543 5,10- methylenetetrahydromethanopterin reductase; luciferase-like monooxygenase complement(4092564..4093613) Actinosynnema mirum DSM 43827 8327713 YP_003101262.1 CDS Amir_3524 NC_013093.1 4093675 4094640 D PFAM: aldo/keto reductase; KEGG: scl:sce4235 oxidoreductase; aldo/keto reductase 4093675..4094640 Actinosynnema mirum DSM 43827 8327714 YP_003101263.1 CDS Amir_3525 NC_013093.1 4094704 4095945 R KEGG: FAP75; flagellar associated protein; hypothetical protein complement(4094704..4095945) Actinosynnema mirum DSM 43827 8327715 YP_003101264.1 CDS Amir_3526 NC_013093.1 4096111 4097076 D KEGG: scl:sce2139 hypothetical protein; hypothetical protein 4096111..4097076 Actinosynnema mirum DSM 43827 8327716 YP_003101265.1 CDS Amir_3527 NC_013093.1 4097073 4097303 D hypothetical protein 4097073..4097303 Actinosynnema mirum DSM 43827 8327717 YP_003101266.1 CDS Amir_3528 NC_013093.1 4097670 4098797 R PFAM: protein of unknown function DUF450; KEGG: pmy:Pmen_3692 hypothetical protein; hypothetical protein complement(4097670..4098797) Actinosynnema mirum DSM 43827 8327718 YP_003101267.1 CDS Amir_3529 NC_013093.1 4099050 4099529 D PFAM: GCN5-related N-acetyltransferase; KEGG: rpd:RPD_1351 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 4099050..4099529 Actinosynnema mirum DSM 43827 8327719 YP_003101268.1 CDS Amir_3530 NC_013093.1 4099768 4100571 R PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: scl:sce6697 transcriptional regulator; TetR family transcriptional regulator complement(4099768..4100571) Actinosynnema mirum DSM 43827 8327720 YP_003101269.1 CDS Amir_3531 NC_013093.1 4100650 4102914 D PFAM: ABC transporter; KEGG: scl:sce6315 excinuclease ABC subunit A; ABC transporter 4100650..4102914 Actinosynnema mirum DSM 43827 8327721 YP_003101270.1 CDS Amir_3532 NC_013093.1 4103007 4103780 D PFAM: FAD-binding 9 siderophore-interacting domain protein; siderophore-interacting protein; KEGG: mxa:MXAN_3639 iron-chelator utilization protein; FAD-binding 9 siderophore-interacting domain-containing protein 4103007..4103780 Actinosynnema mirum DSM 43827 8327722 YP_003101271.1 CDS Amir_3533 NC_013093.1 4103936 4107130 R PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; hypothetical protein; SMART: regulatory protein LuxR; KEGG: SNF2 superfamily protein; LuxR family transcriptional regulator complement(4103936..4107130) Actinosynnema mirum DSM 43827 8327723 YP_003101272.1 CDS Amir_3534 NC_013093.1 4107893 4108639 D PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: lch:Lcho_2886 IclR family transcriptional regulator; IclR family transcriptional regulator 4107893..4108639 Actinosynnema mirum DSM 43827 8327724 YP_003101273.1 CDS Amir_3535 NC_013093.1 4108709 4109452 D hypothetical protein 4108709..4109452 Actinosynnema mirum DSM 43827 8327725 YP_003101274.1 CDS Amir_3536 NC_013093.1 4109560 4110729 D PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: hypothetical protein; cellulose-binding family protein 4109560..4110729 Actinosynnema mirum DSM 43827 8327726 YP_003101275.1 CDS Amir_3537 NC_013093.1 4110841 4111917 D PFAM: Ricin B lectin; lipolytic protein G-D-S-L family; SMART: Ricin B lectin; KEGG: hypothetical protein; Ricin B lectin 4110841..4111917 Actinosynnema mirum DSM 43827 8327727 YP_003101276.1 CDS Amir_3538 NC_013093.1 4112009 4112995 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bsu:BSU27440 glutamine ABC transporter (glutamine-binding protein); family 3 extracellular solute-binding protein 4112009..4112995 Actinosynnema mirum DSM 43827 8327728 YP_003101277.1 CDS Amir_3539 NC_013093.1 4113000 4114049 D hypothetical protein 4113000..4114049 Actinosynnema mirum DSM 43827 8327729 YP_003101278.1 CDS Amir_3540 NC_013093.1 4114114 4114485 R hypothetical protein complement(4114114..4114485) Actinosynnema mirum DSM 43827 8327730 YP_003101279.1 CDS Amir_3541 NC_013093.1 4114612 4115649 D PFAM: alanine dehydrogenase/PNT domain protein; KEGG: sil:SPO3307 saccharopine dehydrogenase; alanine dehydrogenase/PNT domain-containing protein 4114612..4115649 Actinosynnema mirum DSM 43827 8327731 YP_003101280.1 CDS Amir_3542 NC_013093.1 4115642 4116790 D PFAM: saccharopine dehydrogenase; 6- phosphogluconate dehydrogenase NAD-binding; KEGG: sit:TM1040_0106 saccharopine dehydrogenase (NADP+, L-glutamate forming); saccharopine dehydrogenase 4115642..4116790 Actinosynnema mirum DSM 43827 8327732 YP_003101281.1 CDS Amir_3544 NC_013093.1 4117655 4119286 D KEGG: scl:sce3550 hypothetical protein; hypothetical protein 4117655..4119286 Actinosynnema mirum DSM 43827 8327734 YP_003101282.1 CDS Amir_3545 NC_013093.1 4119289 4119915 R PFAM: uracil-DNA glycosylase; KEGG: met:M446_1657 uracil-DNA glycosylase protein; uracil-DNA glycosylase complement(4119289..4119915) Actinosynnema mirum DSM 43827 8327735 YP_003101283.1 CDS Amir_3546 NC_013093.1 4120025 4120546 R hypothetical protein complement(4120025..4120546) Actinosynnema mirum DSM 43827 8327736 YP_003101284.1 CDS Amir_3547 NC_013093.1 4120859 4122058 D PFAM: major facilitator superfamily MFS_1; KEGG: atc:AGR_C_1839 hypothetical protein; major facilitator superfamily protein 4120859..4122058 Actinosynnema mirum DSM 43827 8327737 YP_003101285.1 CDS Amir_3548 NC_013093.1 4122135 4122650 D hypothetical protein 4122135..4122650 Actinosynnema mirum DSM 43827 8327738 YP_003101286.1 CDS Amir_3549 NC_013093.1 4122661 4123149 R PFAM: GCN5-related N-acetyltransferase; KEGG: mrd:Mrad2831_3652 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(4122661..4123149) Actinosynnema mirum DSM 43827 8327739 YP_003101287.1 CDS Amir_3550 NC_013093.1 4123340 4124458 D PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; KEGG: hypothetical protein; glycoside hydrolase family protein 4123340..4124458 Actinosynnema mirum DSM 43827 8327740 YP_003101288.1 CDS Amir_3551 NC_013093.1 4124841 4126031 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin complement(4124841..4126031) Actinosynnema mirum DSM 43827 8327741 YP_003101289.1 CDS Amir_3552 NC_013093.1 4126140 4127087 R PFAM: alpha/beta hydrolase fold; KEGG: predicted protein; alpha/beta hydrolase fold protein complement(4126140..4127087) Actinosynnema mirum DSM 43827 8327742 YP_003101290.1 CDS Amir_3553 NC_013093.1 4127299 4129158 D PFAM: glycosyl transferase family 2; KEGG: rru:Rru_A2348 glycosyl transferase; family 2 glycosyl transferase 4127299..4129158 Actinosynnema mirum DSM 43827 8327743 YP_003101291.1 CDS Amir_3554 NC_013093.1 4129182 4130693 D PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA2757 benzoate-CoA ligase; AMP-dependent synthetase and ligase 4129182..4130693 Actinosynnema mirum DSM 43827 8327744 YP_003101292.1 CDS Amir_3555 NC_013093.1 4130785 4131129 D hypothetical protein 4130785..4131129 Actinosynnema mirum DSM 43827 8327745 YP_003101293.1 CDS Amir_3556 NC_013093.1 4131145 4131780 R hypothetical protein complement(4131145..4131780) Actinosynnema mirum DSM 43827 8327746 YP_003101294.1 CDS Amir_3557 NC_013093.1 4131830 4132297 R hypothetical protein complement(4131830..4132297) Actinosynnema mirum DSM 43827 8327747 YP_003101295.1 CDS Amir_3558 NC_013093.1 4132426 4132929 D TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: xau:Xaut_0976 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 4132426..4132929 Actinosynnema mirum DSM 43827 8327748 YP_003101296.1 CDS Amir_3559 NC_013093.1 4132926 4133984 D TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bha:BH3670 attenuator for lytABC and LytR expression; cell envelope-related transcriptional attenuator 4132926..4133984 Actinosynnema mirum DSM 43827 8327749 YP_003101297.1 CDS Amir_3561 NC_013093.1 4134452 4135474 D PFAM: luciferase-like monooxygenase; KEGG: alkanal monooxygenase (bacterial liciferase alpha chain) like protein; luciferase-like monooxygenase 4134452..4135474 Actinosynnema mirum DSM 43827 8327751 YP_003101298.1 CDS Amir_3562 NC_013093.1 4135526 4136509 R PFAM: Bile acid:sodium symporter; KEGG: gox:GOX0688 efflux protein; Bile acid:sodium symporter complement(4135526..4136509) Actinosynnema mirum DSM 43827 8327752 YP_003101299.1 CDS Amir_3563 NC_013093.1 4136642 4137565 D PFAM: aminoglycoside phosphotransferase; KEGG: smt:Smal_1721 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 4136642..4137565 Actinosynnema mirum DSM 43827 8327753 YP_003101300.1 CDS Amir_3564 NC_013093.1 4137794 4140976 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: shn:Shewana3_1740 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 4137794..4140976 Actinosynnema mirum DSM 43827 8327754 YP_003101301.1 CDS Amir_3565 NC_013093.1 4141041 4141610 R PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator complement(4141041..4141610) Actinosynnema mirum DSM 43827 8327755 YP_003101302.1 CDS Amir_3566 NC_013093.1 4141708 4142667 D PFAM: aldo/keto reductase; KEGG: hne:HNE_2225 aldo/keto reductase family oxidoreductase; aldo/keto reductase 4141708..4142667 Actinosynnema mirum DSM 43827 8327756 YP_003101303.1 CDS Amir_3567 NC_013093.1 4142749 4143657 D PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bur:Bcep18194_B0145 esterase/lipase/thioesterase; alpha/beta hydrolase fold-3 domain-containing protein 4142749..4143657 Actinosynnema mirum DSM 43827 8327757 YP_003101304.1 CDS Amir_3568 NC_013093.1 4143668 4144876 R PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce0310 acetyltransferase; GCN5-like N-acetyltransferase complement(4143668..4144876) Actinosynnema mirum DSM 43827 8327758 YP_003101305.1 CDS Amir_3569 NC_013093.1 4145071 4146525 D PFAM: glycoside hydrolase family 43; glycosyl hydrolase family 32 domain protein; KEGG: pzu:PHZ_c2480 xylosidase/arabinosidase; glycoside hydrolase family protein 4145071..4146525 Actinosynnema mirum DSM 43827 8327759 YP_003101306.1 CDS Amir_3570 NC_013093.1 4146737 4147120 R hypothetical protein complement(4146737..4147120) Actinosynnema mirum DSM 43827 8327760 YP_003101307.1 CDS Amir_3571 NC_013093.1 4147372 4150236 D PFAM: transcriptional activator domain; hypothetical protein; NB-ARC domain protein; transcriptional regulator domain protein; SMART: hypothetical protein; KEGG: scl:sce6858 hypothetical protein; SARP family transcriptional regulator 4147372..4150236 Actinosynnema mirum DSM 43827 8327761 YP_003101308.1 CDS Amir_3572 NC_013093.1 4150285 4150695 R KEGG: hypothetical protein; hypothetical protein complement(4150285..4150695) Actinosynnema mirum DSM 43827 8327762 YP_003101309.1 CDS Amir_3573 NC_013093.1 4150843 4151412 R PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: afw:Anae109_0915 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator complement(4150843..4151412) Actinosynnema mirum DSM 43827 8327763 YP_003101310.1 CDS Amir_3574 NC_013093.1 4151424 4152044 R PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_0902 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator complement(4151424..4152044) Actinosynnema mirum DSM 43827 8327764 YP_003101311.1 CDS Amir_3575 NC_013093.1 4152347 4153597 R PFAM: major facilitator superfamily MFS_1; KEGG: gbm:Gbem_1224 major facilitator superfamily MFS_1; major facilitator superfamily protein complement(4152347..4153597) Actinosynnema mirum DSM 43827 8327765 YP_003101312.1 CDS Amir_3576 NC_013093.1 4153726 4155045 R PFAM: cytochrome P450; KEGG: scl:sce0675 cytochrome P450 CYP267A1; cytochrome P450 complement(4153726..4155045) Actinosynnema mirum DSM 43827 8327766 YP_003101313.1 CDS Amir_3577 NC_013093.1 4155042 4162280 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3618 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(4155042..4162280) Actinosynnema mirum DSM 43827 8327767 YP_003101314.1 CDS Amir_3578 NC_013093.1 4162304 4168600 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3636 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(4162304..4168600) Actinosynnema mirum DSM 43827 8327768 YP_003101315.1 CDS Amir_3579 NC_013093.1 4168784 4168987 D PFAM: MbtH domain protein; KEGG: scl:sce3255 hypothetical protein; MbtH domain-containing protein 4168784..4168987 Actinosynnema mirum DSM 43827 8327769 YP_003101316.1 CDS Amir_3580 NC_013093.1 4169016 4171337 D PFAM: Lantibiotic dehydratase domain protein; KEGG: scl:sce2385 hypothetical protein; Lantibiotic dehydratase domain-containing protein 4169016..4171337 Actinosynnema mirum DSM 43827 8327770 YP_003101317.1 CDS Amir_3581 NC_013093.1 4171337 4172803 D TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_1089 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein 4171337..4172803 Actinosynnema mirum DSM 43827 8327771 YP_003101318.1 CDS Amir_3582 NC_013093.1 4172800 4174209 D PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_3217 pyridoxal-5'-phosphate- dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit 4172800..4174209 Actinosynnema mirum DSM 43827 8327772 YP_003101319.1 CDS Amir_3584 NC_013093.1 4174459 4176744 D PFAM: Lantibiotic dehydratase domain protein; KEGG: scl:sce2385 hypothetical protein; Lantibiotic dehydratase domain-containing protein 4174459..4176744 Actinosynnema mirum DSM 43827 8327774 YP_003101320.1 CDS Amir_3585 NC_013093.1 4176860 4177807 D PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: ornithine cyclodeaminase; ornithine cyclodeaminase/mu-crystallin 4176860..4177807 Actinosynnema mirum DSM 43827 8327775 YP_003101321.1 CDS Amir_3586 NC_013093.1 4177869 4178378 D hypothetical protein 4177869..4178378 Actinosynnema mirum DSM 43827 8327776 YP_003101322.1 CDS Amir_3587 NC_013093.1 4178482 4178610 D hypothetical protein 4178482..4178610 Actinosynnema mirum DSM 43827 8327777 YP_003101323.1 CDS Amir_3588 NC_013093.1 4178673 4179194 D KEGG: mxa:MXAN_2219 hypothetical protein; hypothetical protein 4178673..4179194 Actinosynnema mirum DSM 43827 8327778 YP_003101324.1 CDS Amir_3589 NC_013093.1 4179449 4180147 D TIGRFAM: cobalamin biosynthesis protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: glo:Glov_3660 cobalamin biosynthesis protein CbiM; cobalamin biosynthesis protein CbiM 4179449..4180147 Actinosynnema mirum DSM 43827 8327779 YP_003101325.1 CDS Amir_3590 NC_013093.1 4180140 4180496 D PFAM: cobalt transport protein CbiN; KEGG: kpn:KPN_03187 cobalt transport protein CbiN; cobalt transport protein CbiN 4180140..4180496 Actinosynnema mirum DSM 43827 8327780 YP_003101326.1 CDS Amir_3591 NC_013093.1 4180498 4181265 D TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; KEGG: mag:amb0277 ABC-type cobalt transport system; cobalt ABC transporter inner membrane protein 4180498..4181265 Actinosynnema mirum DSM 43827 8327781 YP_003101327.1 CDS Amir_3592 NC_013093.1 4181262 4182077 D KEGG: mag:amb0278 ABC-type cobalt transport system; TIGRFAM: cobalt ABC transporter ATPase; PFAM: ABC transporter; SMART: ATPase AAA; cobalt ABC transporter ATPase 4181262..4182077 Actinosynnema mirum DSM 43827 8327782 YP_003101328.1 CDS Amir_3593 NC_013093.1 4182111 4182653 R KEGG: bbt:BBta_2404 hypothetical protein; hypothetical protein complement(4182111..4182653) Actinosynnema mirum DSM 43827 8327783 YP_003101329.1 CDS Amir_3594 NC_013093.1 4182747 4183583 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: azc:AZC_1457 transcriptional regulator; MerR family transcriptional regulator complement(4182747..4183583) Actinosynnema mirum DSM 43827 8327784 YP_003101330.1 CDS Amir_3595 NC_013093.1 4183752 4185341 D KEGG: bha:BH1072 hypothetical protein; PucR family transcriptional regulator 4183752..4185341 Actinosynnema mirum DSM 43827 8327785 YP_003101331.1 CDS Amir_3596 NC_013093.1 4185503 4186777 D PFAM: FAD dependent oxidoreductase; KEGG: xca:xccb100_1581 D-amino-acid dehydrogenase; FAD dependent oxidoreductase 4185503..4186777 Actinosynnema mirum DSM 43827 8327786 YP_003101332.1 CDS Amir_3597 NC_013093.1 4186874 4187341 D PFAM: transcription elongation factor GreA/GreB domain protein; GreA/GreB family elongation factor 4186874..4187341 Actinosynnema mirum DSM 43827 8327787 YP_003101333.1 CDS Amir_3598 NC_013093.1 4187453 4187641 R hypothetical protein complement(4187453..4187641) Actinosynnema mirum DSM 43827 8327788 YP_003101334.1 CDS Amir_3599 NC_013093.1 4187625 4188377 R PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: scl:sce2341 hypothetical protein; Activator of Hsp90 ATPase 1 family protein complement(4187625..4188377) Actinosynnema mirum DSM 43827 8327789 YP_003101335.1 CDS Amir_3600 NC_013093.1 4188414 4189622 R PFAM: cytochrome P450; KEGG: scl:sce0675 cytochrome P450 CYP267A1; cytochrome P450 complement(4188414..4189622) Actinosynnema mirum DSM 43827 8327790 YP_003101336.1 CDS Amir_3601 NC_013093.1 4189619 4189840 R PFAM: MbtH domain protein; KEGG: bcy:Bcer98_1759 MbtH domain-containing protein; MbtH domain-containing protein complement(4189619..4189840) Actinosynnema mirum DSM 43827 8327791 YP_003101337.1 CDS Amir_3602 NC_013093.1 4189882 4214517 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; methyltransferase type 11; methyltransferase type 12; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: smd:Smed_6472 amino acid adenylation domain; cyclic nucleotide-binding protein complement(4189882..4214517) Actinosynnema mirum DSM 43827 8327792 YP_003101338.1 CDS Amir_3603 NC_013093.1 4214919 4217807 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: neu:NE0720 ABC transporter permease/ATP- binding protein; ABC transporter complement(4214919..4217807) Actinosynnema mirum DSM 43827 8327793 YP_003101339.1 CDS Amir_3604 NC_013093.1 4217877 4218215 R KEGG: nmu:Nmul_A0032 hypothetical protein; hypothetical protein complement(4217877..4218215) Actinosynnema mirum DSM 43827 8327794 YP_003101340.1 CDS Amir_3605 NC_013093.1 4218854 4219345 D KEGG: mex:Mext_0734 hypothetical protein; hypothetical protein 4218854..4219345 Actinosynnema mirum DSM 43827 8327795 YP_003101341.1 CDS Amir_3606 NC_013093.1 4219418 4220605 R PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sfu:Sfum_2453 serine phosphatase; protein serine/threonine phosphatase complement(4219418..4220605) Actinosynnema mirum DSM 43827 8327796 YP_003101342.1 CDS Amir_3607 NC_013093.1 4220767 4221246 D hypothetical protein 4220767..4221246 Actinosynnema mirum DSM 43827 8327797 YP_003101343.1 CDS Amir_3608 NC_013093.1 4221253 4222173 R PFAM: NAD-dependent epimerase/dehydratase; KEGG: ade:Adeh_0027 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(4221253..4222173) Actinosynnema mirum DSM 43827 8327798 YP_003101344.1 CDS Amir_3609 NC_013093.1 4222273 4222959 D PFAM: regulatory protein TetR; KEGG: mes:Meso_0701 transcriptional regulator, TetR family; TetR family transcriptional regulator 4222273..4222959 Actinosynnema mirum DSM 43827 8327799 YP_003101345.1 CDS Amir_3610 NC_013093.1 4223112 4225286 D PFAM: extracellular solute-binding protein family 1; KEGG: thuE; trehalosemaltose ABC transporter; family 1 extracellular solute-binding protein 4223112..4225286 Actinosynnema mirum DSM 43827 8327800 YP_003101346.1 CDS Amir_3611 NC_013093.1 4225342 4227852 R PFAM: protein of unknown function DUF214; KEGG: hha:Hhal_1416 protein of unknown function DUF214; hypothetical protein complement(4225342..4227852) Actinosynnema mirum DSM 43827 8327801 YP_003101347.1 CDS Amir_3612 NC_013093.1 4227852 4228547 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: shl:Shal_1616 lipoprotein releasing system, ATP-binding protein; ABC transporter complement(4227852..4228547) Actinosynnema mirum DSM 43827 8327802 YP_003101348.1 CDS Amir_3613 NC_013093.1 4228544 4230241 R PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_5165 GMC oxidoreductase family protein; glucose-methanol-choline oxidoreductase complement(4228544..4230241) Actinosynnema mirum DSM 43827 8327803 YP_003101349.1 CDS Amir_3614 NC_013093.1 4230238 4230708 R PFAM: cyclase/dehydrase; KEGG: psp:PSPPH_4312 hypothetical protein; cyclase/dehydrase complement(4230238..4230708) Actinosynnema mirum DSM 43827 8327804 YP_003101350.1 CDS Amir_3615 NC_013093.1 4230722 4232002 R PFAM: aminotransferase class-III; KEGG: esa:ESA_03492 putrescine--2-oxoglutarate aminotransferase; class III aminotransferase complement(4230722..4232002) Actinosynnema mirum DSM 43827 8327805 YP_003101351.1 CDS Amir_3616 NC_013093.1 4232161 4233291 R KEGG: bph:Bphy_6313 isobutylamine N-hydroxylase; isobutylamine N-hydroxylase complement(4232161..4233291) Actinosynnema mirum DSM 43827 8327806 YP_003101352.1 CDS Amir_3617 NC_013093.1 4233288 4234934 R PFAM: Aldehyde Dehydrogenase; KEGG: pca:Pcar_1701 aldehyde dehydrogenase, NAD- linked; aldehyde dehydrogenase complement(4233288..4234934) Actinosynnema mirum DSM 43827 8327807 YP_003101353.1 CDS Amir_3618 NC_013093.1 4234968 4235915 R KEGG: plu:plu4388 hypothetical protein; hypothetical protein complement(4234968..4235915) Actinosynnema mirum DSM 43827 8327808 YP_003101354.1 CDS Amir_3619 NC_013093.1 4235952 4236938 R PFAM: protein of unknown function DUF470; protein of unknown function DUF472; protein of unknown function DUF471; KEGG: bph:Bphy_6311 hypothetical protein; hypothetical protein complement(4235952..4236938) Actinosynnema mirum DSM 43827 8327809 YP_003101355.1 CDS Amir_3620 NC_013093.1 4236935 4237429 R KEGG: bph:Bphy_6310 integral membrane protein; integral membrane protein complement(4236935..4237429) Actinosynnema mirum DSM 43827 8327810 YP_003101356.1 CDS Amir_3621 NC_013093.1 4237596 4239299 R KEGG: kpe:KPK_3424 hypothetical protein; hypothetical protein complement(4237596..4239299) Actinosynnema mirum DSM 43827 8327811 YP_003101357.1 CDS Amir_3622 NC_013093.1 4239296 4240201 R PFAM: alpha/beta hydrolase fold; KEGG: hch:HCH_00758 alpha/beta hydrolase; alpha/beta hydrolase fold protein complement(4239296..4240201) Actinosynnema mirum DSM 43827 8327812 YP_003101358.1 CDS Amir_3623 NC_013093.1 4240640 4242430 D PFAM: AMP-dependent synthetase and ligase; KEGG: acp:A2cp1_1619 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 4240640..4242430 Actinosynnema mirum DSM 43827 8327813 YP_003101359.1 CDS Amir_3624 NC_013093.1 4242477 4243025 R KEGG: bac:BamMC406_2852 hexapaptide repeat- containing transferase; hexapaptide repeat-containing transferase complement(4242477..4243025) Actinosynnema mirum DSM 43827 8327814 YP_003101360.1 CDS Amir_3625 NC_013093.1 4243108 4244037 D PFAM: regulatory protein LysR; KEGG: mxa:MXAN_5480 transcriptional regulator, LysR family; LysR family transcriptional regulator 4243108..4244037 Actinosynnema mirum DSM 43827 8327815 YP_003101361.1 CDS Amir_3626 NC_013093.1 4244077 4244553 D KEGG: nar:Saro_3714 hypothetical protein; hypothetical protein 4244077..4244553 Actinosynnema mirum DSM 43827 8327816 YP_003101362.1 CDS Amir_3627 NC_013093.1 4244590 4244919 D hypothetical protein 4244590..4244919 Actinosynnema mirum DSM 43827 8327817 YP_003101363.1 CDS Amir_3628 NC_013093.1 4244938 4245333 R hypothetical protein complement(4244938..4245333) Actinosynnema mirum DSM 43827 8327818 YP_003101364.1 CDS Amir_3629 NC_013093.1 4245567 4246841 D PFAM: major facilitator superfamily MFS_1; KEGG: dac:Daci_3577 major facilitator transporter; major facilitator superfamily protein 4245567..4246841 Actinosynnema mirum DSM 43827 8327819 YP_003101365.1 CDS Amir_3630 NC_013093.1 4246895 4247770 D PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: mmr:Mmar10_1955 methyltransferase type 11; type 11 methyltransferase 4246895..4247770 Actinosynnema mirum DSM 43827 8327820 YP_003101366.1 CDS Amir_3631 NC_013093.1 4247811 4248650 D hypothetical protein 4247811..4248650 Actinosynnema mirum DSM 43827 8327821 YP_003101367.1 CDS Amir_3632 NC_013093.1 4248762 4249604 R hypothetical protein complement(4248762..4249604) Actinosynnema mirum DSM 43827 8327822 YP_003101368.1 CDS Amir_3635 NC_013093.1 4251529 4252179 D hypothetical protein 4251529..4252179 Actinosynnema mirum DSM 43827 8327825 YP_003101369.1 CDS Amir_3636 NC_013093.1 4252350 4252796 D hypothetical protein 4252350..4252796 Actinosynnema mirum DSM 43827 8327826 YP_003101370.1 CDS Amir_3637 NC_013093.1 4252777 4254678 D KEGG: bbr:BB2304 competence protein; hypothetical protein 4252777..4254678 Actinosynnema mirum DSM 43827 8327827 YP_003101371.1 CDS Amir_3638 NC_013093.1 4254939 4255286 R KEGG: gbm:Gbem_2481 hypothetical protein; hypothetical protein complement(4254939..4255286) Actinosynnema mirum DSM 43827 8327828 YP_003101372.1 CDS Amir_3639 NC_013093.1 4255283 4256830 R hypothetical protein complement(4255283..4256830) Actinosynnema mirum DSM 43827 8327829 YP_003101373.1 CDS Amir_3641 NC_013093.1 4257471 4257653 D hypothetical protein 4257471..4257653 Actinosynnema mirum DSM 43827 8327831 YP_003101374.1 CDS Amir_3642 NC_013093.1 4257650 4257967 D PFAM: transcription factor WhiB; transcription factor WhiB 4257650..4257967 Actinosynnema mirum DSM 43827 8327832 YP_003101375.1 CDS Amir_3643 NC_013093.1 4257997 4258284 D hypothetical protein 4257997..4258284 Actinosynnema mirum DSM 43827 8327833 YP_003101376.1 CDS Amir_3645 NC_013093.1 4258904 4260931 D PFAM: cell divisionFtsK/SpoIIIE; KEGG: pha:PSHAb0091 cell divisionFtsK/SpoIIIE domain-containing protein; cell division protein FtsK/SpoIIIE 4258904..4260931 Actinosynnema mirum DSM 43827 8327835 YP_003101377.1 CDS Amir_3646 NC_013093.1 4260993 4261898 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein complement(4260993..4261898) Actinosynnema mirum DSM 43827 8327836 YP_003101378.1 CDS Amir_3647 NC_013093.1 4261895 4262167 R hypothetical protein complement(4261895..4262167) Actinosynnema mirum DSM 43827 8327837 YP_003101379.1 CDS Amir_3648 NC_013093.1 4262325 4263176 D SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 4262325..4263176 Actinosynnema mirum DSM 43827 8327838 YP_003101380.1 CDS Amir_3649 NC_013093.1 4263218 4263445 D PFAM: protein of unknown function DUF397; hypothetical protein 4263218..4263445 Actinosynnema mirum DSM 43827 8327839 YP_003101381.1 CDS Amir_3650 NC_013093.1 4263636 4265021 D KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein 4263636..4265021 Actinosynnema mirum DSM 43827 8327840 YP_003101382.1 CDS Amir_3651 NC_013093.1 4265024 4265683 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hypothetical protein; HAD superfamily hydrolase complement(4265024..4265683) Actinosynnema mirum DSM 43827 8327841 YP_003101383.1 CDS Amir_3652 NC_013093.1 4266080 4266694 D hypothetical protein 4266080..4266694 Actinosynnema mirum DSM 43827 8327842 YP_003101384.1 CDS Amir_3653 NC_013093.1 4266640 4267470 R PFAM: endonuclease/exonuclease/phosphatase; KEGG: rru:Rru_A2021 endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase complement(4266640..4267470) Actinosynnema mirum DSM 43827 8327843 YP_003101385.1 CDS Amir_3654 NC_013093.1 4267467 4268519 R PFAM: aldo/keto reductase; KEGG: ecp:ECP_1719 oxidoreductase YdjG; aldo/keto reductase complement(4267467..4268519) Actinosynnema mirum DSM 43827 8327844 YP_003101386.1 CDS Amir_3655 NC_013093.1 4268681 4270816 D PFAM: Radical SAM domain protein; KEGG: rpb:RPB_2074 radical SAM binding protein; Radical SAM domain-containing protein 4268681..4270816 Actinosynnema mirum DSM 43827 8327845 YP_003101387.1 CDS Amir_3656 NC_013093.1 4270966 4271193 D hypothetical protein 4270966..4271193 Actinosynnema mirum DSM 43827 8327846 YP_003101388.1 CDS Amir_3657 NC_013093.1 4271244 4271564 D hypothetical protein 4271244..4271564 Actinosynnema mirum DSM 43827 8327847 YP_003101389.1 CDS Amir_3658 NC_013093.1 4271933 4272751 D hypothetical protein 4271933..4272751 Actinosynnema mirum DSM 43827 8327848 YP_003101390.1 CDS Amir_3659 NC_013093.1 4272803 4273645 D PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 4272803..4273645 Actinosynnema mirum DSM 43827 8327849 YP_003101391.1 CDS Amir_3661 NC_013093.1 4275175 4276341 R PFAM: glycosyl transferase group 1; KEGG: sal:Sala_1921 glycosyl transferase, group 1; group 1 glycosyl transferase complement(4275175..4276341) Actinosynnema mirum DSM 43827 8327851 YP_003101392.1 CDS Amir_3662 NC_013093.1 4276470 4277714 R PFAM: cytochrome P450; KEGG: bxe:Bxe_C0945 cytochrome P450; cytochrome P450 complement(4276470..4277714) Actinosynnema mirum DSM 43827 8327852 YP_003101393.1 CDS Amir_3663 NC_013093.1 4277795 4278673 R PFAM: GCN5-related N-acetyltransferase; KEGG: cak:Caul_3937 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(4277795..4278673) Actinosynnema mirum DSM 43827 8327853 YP_003101394.1 CDS Amir_3664 NC_013093.1 4278732 4280087 R TIGRFAM: crotonyl-CoA reductase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: dds:Ddes_1332 crotonyl-CoA reductase; crotonyl-CoA reductase complement(4278732..4280087) Actinosynnema mirum DSM 43827 8327854 YP_003101395.1 CDS Amir_3665 NC_013093.1 4280158 4281126 R PFAM: aspartyl/Asparaginyl beta-hydroxylase; KEGG: similar to aspartyl/asparaginyl beta- hydroxylase; peptide-aspartate beta-dioxygenase complement(4280158..4281126) Actinosynnema mirum DSM 43827 8327855 YP_003101396.1 CDS Amir_3666 NC_013093.1 4281123 4281722 R PFAM: Ankyrin; SMART: Ankyrin; KEGG: Os03g0655500; hypothetical protein; Ankyrin complement(4281123..4281722) Actinosynnema mirum DSM 43827 8327856 YP_003101397.1 CDS Amir_3667 NC_013093.1 4281712 4283565 R PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: pca:Pcar_1259 ATP-binding transport protein; multicopy suppressor of HtrB; ABC transporter complement(4281712..4283565) Actinosynnema mirum DSM 43827 8327857 YP_003101398.1 CDS Amir_3668 NC_013093.1 4283562 4284515 R PFAM: aspartyl/Asparaginyl beta-hydroxylase; KEGG: hypothetical protein; peptide-aspartate beta-dioxygenase complement(4283562..4284515) Actinosynnema mirum DSM 43827 8327858 YP_003101399.1 CDS Amir_3669 NC_013093.1 4284512 4285978 R TIGRFAM: cytidyltransferase-related domain protein; PFAM: PfkB domain protein; cytidylyltransferase; KEGG: nmu:Nmul_A1792 bifunctional ADP-heptose synthase; cytidyltransferase complement(4284512..4285978) Actinosynnema mirum DSM 43827 8327859 YP_003101400.1 CDS Amir_3670 NC_013093.1 4286007 4287632 R PFAM: carbamoyltransferase; KEGG: bra:BRADO2235 carbamoyltransferase family protein; carbamoyltransferase complement(4286007..4287632) Actinosynnema mirum DSM 43827 8327860 YP_003101401.1 CDS Amir_3671 NC_013093.1 4287629 4288771 R PFAM: glycosyl transferase family 9; KEGG: rso:RSc0565 ADP-heptose--lipopolysaccharide heptosyltransferase II protein; glycosyl transferase family protein complement(4287629..4288771) Actinosynnema mirum DSM 43827 8327861 YP_003101402.1 CDS Amir_3672 NC_013093.1 4288803 4289390 R PFAM: MbtH domain protein; KEGG: bbt:BBta_1084 hypothetical protein; MbtH domain-containing protein complement(4288803..4289390) Actinosynnema mirum DSM 43827 8327862 YP_003101403.1 CDS Amir_3673 NC_013093.1 4289471 4290478 R PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: pen:PSEEN3233 SyrP protein; taurine catabolism dioxygenase TauD/TfdA complement(4289471..4290478) Actinosynnema mirum DSM 43827 8327863 YP_003101404.1 CDS Amir_3674 NC_013093.1 4290517 4293099 R PFAM: AMP-dependent synthetase and ligase; nitroreductase; phosphopantetheine-binding; KEGG: pen:PSEEN2716 non-ribosomal peptide synthetase; AMP-dependent synthetase and ligase complement(4290517..4293099) Actinosynnema mirum DSM 43827 8327864 YP_003101405.1 CDS Amir_3675 NC_013093.1 4293096 4300955 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; Non-ribosomal peptide synthetase; condensation domain protein; KEGG: psb:Psyr_1792 amino acid adenylation; amino acid adenylation domain-containing protein complement(4293096..4300955) Actinosynnema mirum DSM 43827 8327865 YP_003101406.1 CDS Amir_3676 NC_013093.1 4300948 4302864 R KEGG: bbt:BBta_3705 asparagine synthase, glutamine- hydrolyzing; TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; asparagine synthase complement(4300948..4302864) Actinosynnema mirum DSM 43827 8327866 YP_003101407.1 CDS Amir_3677 NC_013093.1 4302870 4304597 R PFAM: aspartyl/Asparaginyl beta-hydroxylase; KEGG: hypothetical protein; aspartyl/Asparaginyl beta-hydroxylase complement(4302870..4304597) Actinosynnema mirum DSM 43827 8327867 YP_003101408.1 CDS Amir_3678 NC_013093.1 4304594 4305583 R PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: aba:Acid345_0895 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(4304594..4305583) Actinosynnema mirum DSM 43827 8327868 YP_003101409.1 CDS Amir_3679 NC_013093.1 4305580 4307388 R PFAM: condensation domain protein; phosphopantetheine-binding; KEGG: peptide synthetase; condensation domain-containing protein complement(4305580..4307388) Actinosynnema mirum DSM 43827 8327869 YP_003101410.1 CDS Amir_3680 NC_013093.1 4307375 4315540 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein complement(4307375..4315540) Actinosynnema mirum DSM 43827 8327870 YP_003101411.1 CDS Amir_3681 NC_013093.1 4315537 4318965 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: eca:ECA1487 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(4315537..4318965) Actinosynnema mirum DSM 43827 8327871 YP_003101412.1 CDS Amir_3682 NC_013093.1 4318962 4323455 R PFAM: KR domain protein; beta-ketoacyl synthase; acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3631 polyketide synthase type I; KR domain-containing protein complement(4318962..4323455) Actinosynnema mirum DSM 43827 8327872 YP_003101413.1 CDS Amir_3683 NC_013093.1 4323452 4326631 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3636 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(4323452..4326631) Actinosynnema mirum DSM 43827 8327873 YP_003101414.1 CDS Amir_3684 NC_013093.1 4326640 4332969 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein complement(4326640..4332969) Actinosynnema mirum DSM 43827 8327874 YP_003101415.1 CDS Amir_3685 NC_013093.1 4333280 4335754 R PFAM: peptidase S45 penicillin amidase; KEGG: mxa:MXAN_2906 penicillin acylase family protein; peptidase S45 penicillin amidase complement(4333280..4335754) Actinosynnema mirum DSM 43827 8327875 YP_003101416.1 CDS Amir_3686 NC_013093.1 4335932 4337947 R PFAM: condensation domain protein; KEGG: reh:H16_B1685 non-ribosomal peptide synthetase; condensation domain-containing protein complement(4335932..4337947) Actinosynnema mirum DSM 43827 8327876 YP_003101417.1 CDS Amir_3687 NC_013093.1 4338052 4338342 R PFAM: helix-turn-helix HxlR type; KEGG: mlo:mlr2600 hypothetical protein; HxlR family transcriptional regulator complement(4338052..4338342) Actinosynnema mirum DSM 43827 8327877 YP_003101418.1 CDS Amir_3689 NC_013093.1 4340739 4341683 R KEGG: bmv:BMASAVP1_0867 RemN protein; RemN protein complement(4340739..4341683) Actinosynnema mirum DSM 43827 8327879 YP_003101419.1 CDS Amir_3690 NC_013093.1 4342081 4342254 D hypothetical protein 4342081..4342254 Actinosynnema mirum DSM 43827 8327880 YP_003101420.1 CDS Amir_3691 NC_013093.1 4342380 4342895 D PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 4342380..4342895 Actinosynnema mirum DSM 43827 8327881 YP_003101421.1 CDS Amir_3692 NC_013093.1 4343043 4344236 D PFAM: cytochrome P450; KEGG: hypothetical protein; cytochrome P450 4343043..4344236 Actinosynnema mirum DSM 43827 8327882 YP_003101422.1 CDS Amir_3693 NC_013093.1 4344233 4344430 D PFAM: protein of unknown function DUF1271; KEGG: bha:BH1605 ferredoxin; hypothetical protein 4344233..4344430 Actinosynnema mirum DSM 43827 8327883 YP_003101423.1 CDS Amir_3694 NC_013093.1 4344444 4344896 R KEGG: dsh:Dshi_1841 hypothetical protein; hypothetical protein complement(4344444..4344896) Actinosynnema mirum DSM 43827 8327884 YP_003101424.1 CDS Amir_3695 NC_013093.1 4345073 4346884 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bpa:BPP2159 ABC transporter, ATP-binding protein; ABC transporter 4345073..4346884 Actinosynnema mirum DSM 43827 8327885 YP_003101425.1 CDS Amir_3696 NC_013093.1 4346913 4347566 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(4346913..4347566) Actinosynnema mirum DSM 43827 8327886 YP_003101426.1 CDS Amir_3697 NC_013093.1 4347563 4348504 R PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(4347563..4348504) Actinosynnema mirum DSM 43827 8327887 YP_003101427.1 CDS Amir_3698 NC_013093.1 4348510 4349940 R PFAM: beta-lactamase; KEGG: bat:BAS2400 penicillin-binding protein; beta-lactamase complement(4348510..4349940) Actinosynnema mirum DSM 43827 8327888 YP_003101428.1 CDS Amir_3699 NC_013093.1 4350093 4351208 D PFAM: monooxygenase FAD-binding; KEGG: gdj:Gdia_2837 monooxygenase FAD-binding; FAD-binding monooxygenase 4350093..4351208 Actinosynnema mirum DSM 43827 8327889 YP_003101429.1 CDS Amir_3700 NC_013093.1 4351254 4351814 R PFAM: regulatory protein TetR; KEGG: acp:A2cp1_1650 regulatory protein TetR; TetR family transcriptional regulator complement(4351254..4351814) Actinosynnema mirum DSM 43827 8327890 YP_003101430.1 CDS Amir_3701 NC_013093.1 4351972 4352391 D KEGG: nar:Saro_3538 hypothetical protein; hypothetical protein 4351972..4352391 Actinosynnema mirum DSM 43827 8327891 YP_003101431.1 CDS Amir_3702 NC_013093.1 4352474 4353997 R PFAM: protein of unknown function DUF112 transmembrane; KEGG: smd:Smed_0363 protein of unknown function DUF112 transmembrane; hypothetical protein complement(4352474..4353997) Actinosynnema mirum DSM 43827 8327892 YP_003101432.1 CDS Amir_3703 NC_013093.1 4353990 4354484 R KEGG: hypothetical protein; hypothetical protein complement(4353990..4354484) Actinosynnema mirum DSM 43827 8327893 YP_003101433.1 CDS Amir_3704 NC_013093.1 4354481 4355467 R PFAM: conserved hypothetical protein; KEGG: azc:AZC_4334 hypothetical protein; hypothetical protein complement(4354481..4355467) Actinosynnema mirum DSM 43827 8327894 YP_003101434.1 CDS Amir_3705 NC_013093.1 4355612 4357195 D PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: sfu:Sfum_3991 signal transduction histidine kinase regulating citrate/malate metabolism; signal transduction histidine kinase regulating citrate/malate metabolism 4355612..4357195 Actinosynnema mirum DSM 43827 8327895 YP_003101435.1 CDS Amir_3706 NC_013093.1 4357198 4357878 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: vco:VC0395_A1209 response regulator; response regulator receiver and unknown domain-containing protein 4357198..4357878 Actinosynnema mirum DSM 43827 8327896 YP_003101436.1 CDS Amir_3707 NC_013093.1 4357920 4358309 R PFAM: YCII-related; KEGG: scl:sce5148 hypothetical protein; YCII-like protein complement(4357920..4358309) Actinosynnema mirum DSM 43827 8327897 YP_003101437.1 CDS Amir_3708 NC_013093.1 4358375 4359940 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: rsq:Rsph17025_2978 alpha amylase, catalytic region; alpha amylase catalytic subunit complement(4358375..4359940) Actinosynnema mirum DSM 43827 8327898 YP_003101438.1 CDS Amir_3709 NC_013093.1 4359937 4360914 R PFAM: luciferase-like monooxygenase; KEGG: mex:Mext_1273 dehydrogenase protein; luciferase-like monooxygenase complement(4359937..4360914) Actinosynnema mirum DSM 43827 8327899 YP_003101439.1 CDS Amir_3710 NC_013093.1 4360965 4361741 R SMART: ATPase AAA; KEGG: rme:Rmet_4896 SMC protein-like protein; ATPase AAA complement(4360965..4361741) Actinosynnema mirum DSM 43827 8327900 YP_003101440.1 CDS Amir_3711 NC_013093.1 4361845 4362468 R PFAM: regulatory protein TetR; KEGG: tmz:Tmz1t_0804 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(4361845..4362468) Actinosynnema mirum DSM 43827 8327901 YP_003101441.1 CDS Amir_3712 NC_013093.1 4362533 4363393 D PFAM: ketopantoate reductase ApbA/PanE domain protein; KEGG: scl:sce9123 oxidoreductase; ketopantoate reductase ApbA/PanE domain-containing protein 4362533..4363393 Actinosynnema mirum DSM 43827 8327902 YP_003101442.1 CDS Amir_3713 NC_013093.1 4363499 4363975 R KEGG: mno:Mnod_4965 hypothetical protein; hypothetical protein complement(4363499..4363975) Actinosynnema mirum DSM 43827 8327903 YP_003101443.1 CDS Amir_3714 NC_013093.1 4363995 4364531 D PFAM: regulatory protein TetR; KEGG: baa:BA_3806 bacterial regulatory proteins, TetR family; TetR family transcriptional regulator 4363995..4364531 Actinosynnema mirum DSM 43827 8327904 YP_003101444.1 CDS Amir_3715 NC_013093.1 4364612 4365190 R PFAM: FxsA cytoplasmic membrane protein; KEGG: mxa:MXAN_5566 FxsA-like protein; FxsA cytoplasmic membrane protein complement(4364612..4365190) Actinosynnema mirum DSM 43827 8327905 YP_003101445.1 CDS Amir_3716 NC_013093.1 4365277 4366656 D PFAM: Radical SAM domain protein; KEGG: mxa:MXAN_4699 L-lysine 2,3- aminomutase; lysine 2,3-aminomutase 4365277..4366656 Actinosynnema mirum DSM 43827 8327906 YP_003101446.1 CDS Amir_3717 NC_013093.1 4366905 4367285 R hypothetical protein complement(4366905..4367285) Actinosynnema mirum DSM 43827 8327907 YP_003101447.1 CDS Amir_3718 NC_013093.1 4367305 4368297 R PFAM: Mg2 transporter protein CorA family protein; KEGG: rle:pRL120701 transmembrane magnesium and cobalt transport protein; Mg2 transporter protein CorA family protein complement(4367305..4368297) Actinosynnema mirum DSM 43827 8327908 YP_003101448.1 CDS Amir_3719 NC_013093.1 4368359 4369042 D PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: lch:Lcho_0755 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 4368359..4369042 Actinosynnema mirum DSM 43827 8327909 YP_003101449.1 CDS Amir_3720 NC_013093.1 4369177 4370028 D hypothetical protein 4369177..4370028 Actinosynnema mirum DSM 43827 8327910 YP_003101450.1 CDS Amir_3721 NC_013093.1 4370025 4371839 D KEGG: ade:Adeh_3311 hypothetical protein; hypothetical protein 4370025..4371839 Actinosynnema mirum DSM 43827 8327911 YP_003101451.1 CDS Amir_3722 NC_013093.1 4371836 4372927 D hypothetical protein 4371836..4372927 Actinosynnema mirum DSM 43827 8327912 YP_003101452.1 CDS Amir_3723 NC_013093.1 4372993 4373319 R hypothetical protein complement(4372993..4373319) Actinosynnema mirum DSM 43827 8327913 YP_003101453.1 CDS Amir_3724 NC_013093.1 4373506 4375314 D KEGG: bha:BH2614 cytochrome Caa3 oxidase (subunit I); TIGRFAM: cytochrome C oxidase, subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase, subunit I 4373506..4375314 Actinosynnema mirum DSM 43827 8327914 YP_003101454.1 CDS Amir_3725 NC_013093.1 4375763 4376827 D KEGG: dac:Daci_4530 acyl protein synthase/acyl-CoA reductase-like protein; acyl protein synthase/acyl-CoA reductase-like protein 4375763..4376827 Actinosynnema mirum DSM 43827 8327915 YP_003101455.1 CDS Amir_3726 NC_013093.1 4376831 4378306 D PFAM: acyl-CoA reductase; KEGG: aav:Aave_4516 acyl-CoA reductase; acyl-CoA reductase 4376831..4378306 Actinosynnema mirum DSM 43827 8327916 YP_003101456.1 CDS Amir_3727 NC_013093.1 4378383 4380815 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6315 excinuclease ABC subunit A; ABC transporter 4378383..4380815 Actinosynnema mirum DSM 43827 8327917 YP_003101457.1 CDS Amir_3728 NC_013093.1 4380886 4382163 R PFAM: dicarboxylate carrier MatC domain protein; Citrate transporter; KEGG: matC; dicarboxylate-carrier protein; dicarboxylate carrier MatC domain-containing protein complement(4380886..4382163) Actinosynnema mirum DSM 43827 8327918 YP_003101458.1 CDS Amir_3729 NC_013093.1 4382160 4383482 R PFAM: SAF domain protein; homoserine dehydrogenase NAD-binding; KEGG: rru:Rru_A3141 homoserine dehydrogenase, NAD- binding; SAF domain-containing protein complement(4382160..4383482) Actinosynnema mirum DSM 43827 8327919 YP_003101459.1 CDS Amir_3730 NC_013093.1 4383621 4384874 D PFAM: type III effector Hrp-dependent outers; KEGG: pde:Pden_3383 type III effector Hrp-dependent outers; Hrp-dependent type III effector protein 4383621..4384874 Actinosynnema mirum DSM 43827 8327920 YP_003101460.1 CDS Amir_3731 NC_013093.1 4384871 4385533 D PFAM: class II aldolase/adducin family protein; KEGG: hiq:CGSHiGG_08670 aldolase; class II aldolase/adducin family protein 4384871..4385533 Actinosynnema mirum DSM 43827 8327921 YP_003101461.1 CDS Amir_3732 NC_013093.1 4385538 4386389 D PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: psp:PSPPH_4844 DeoR family transcriptional regulator; DeoR family transcriptional regulator 4385538..4386389 Actinosynnema mirum DSM 43827 8327922 YP_003101462.1 CDS Amir_3733 NC_013093.1 4386386 4387201 R PFAM: Bifunctional DNA primase/polymerase; KEGG: bbt:BBta_1244 phage / plasmid primase P4; Bifunctional DNA primase/polymerase complement(4386386..4387201) Actinosynnema mirum DSM 43827 8327923 YP_003101463.1 CDS Amir_3734 NC_013093.1 4387521 4388162 R PFAM: aminoglycoside phosphotransferase; KEGG: mch:Mchl_5542 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase complement(4387521..4388162) Actinosynnema mirum DSM 43827 8327924 YP_003101464.1 CDS Amir_3735 NC_013093.1 4388413 4389528 R PFAM: sodium/calcium exchanger membrane region; KEGG: bph:Bphy_3245 sodium/calcium exchanger membrane region; sodium/calcium exchanger membrane protein complement(4388413..4389528) Actinosynnema mirum DSM 43827 8327925 YP_003101465.1 CDS Amir_3736 NC_013093.1 4389753 4392806 D KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein; PAS/PAC sensor protein 4389753..4392806 Actinosynnema mirum DSM 43827 8327926 YP_003101466.1 CDS Amir_3737 NC_013093.1 4392993 4395221 D PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce3550 hypothetical protein; hypothetical protein 4392993..4395221 Actinosynnema mirum DSM 43827 8327927 YP_003101467.1 CDS Amir_3738 NC_013093.1 4395246 4395611 R TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1431 anti-anti-sigma factor family protein; anti-sigma-factor antagonist complement(4395246..4395611) Actinosynnema mirum DSM 43827 8327928 YP_003101468.1 CDS Amir_3739 NC_013093.1 4395709 4397280 R PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; KEGG: pfo:Pfl01_3138 multi-sensor hybrid histidine kinase; response regulator receiver modulated serine phosphatase complement(4395709..4397280) Actinosynnema mirum DSM 43827 8327929 YP_003101469.1 CDS Amir_3740 NC_013093.1 4397277 4399127 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_0803 histidine kinase; histidine kinase complement(4397277..4399127) Actinosynnema mirum DSM 43827 8327930 YP_003101470.1 CDS Amir_3741 NC_013093.1 4399124 4400143 R PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; KEGG: mch:Mchl_3342 anti-sigma regulatory factor, serine/threonine protein kinase; anti-sigma regulatory factor, serine/threonine protein kinase complement(4399124..4400143) Actinosynnema mirum DSM 43827 8327931 YP_003101471.1 CDS Amir_3742 NC_013093.1 4400145 4400558 R PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: xca:xccb100_3165 sigma-B negative effector; anti-sigma regulatory factor, serine/threonine protein kinase complement(4400145..4400558) Actinosynnema mirum DSM 43827 8327932 YP_003101472.1 CDS Amir_3743 NC_013093.1 4400555 4400932 R PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dac:Daci_4410 anti-sigma-factor antagonist; anti-sigma-factor antagonist complement(4400555..4400932) Actinosynnema mirum DSM 43827 8327933 YP_003101473.1 CDS Amir_3744 NC_013093.1 4400932 4401798 R PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: xac:XAC1269 positive regulator of sigma-B; anti-sigma-factor antagonist complement(4400932..4401798) Actinosynnema mirum DSM 43827 8327934 YP_003101474.1 CDS Amir_3745 NC_013093.1 4402034 4402657 R KEGG: met:M446_0126 hypothetical protein; hypothetical protein complement(4402034..4402657) Actinosynnema mirum DSM 43827 8327935 YP_003101475.1 CDS Amir_3746 NC_013093.1 4402828 4404501 R PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: scl:sce0787 hypothetical protein; glucose-methanol-choline oxidoreductase complement(4402828..4404501) Actinosynnema mirum DSM 43827 8327936 YP_003101476.1 CDS Amir_3747 NC_013093.1 4404561 4406015 R PFAM: FAD dependent oxidoreductase; KEGG: bur:Bcep18194_B2514 lipolytic protein; FAD dependent oxidoreductase complement(4404561..4406015) Actinosynnema mirum DSM 43827 8327937 YP_003101477.1 CDS Amir_3748 NC_013093.1 4406087 4407139 D PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pag:PLES_32251 transcriptional regulator; AraC family transcriptional regulator 4406087..4407139 Actinosynnema mirum DSM 43827 8327938 YP_003101478.1 CDS Amir_3749 NC_013093.1 4407109 4407735 R KEGG: afw:Anae109_3301 hypothetical protein; hypothetical protein complement(4407109..4407735) Actinosynnema mirum DSM 43827 8327939 YP_003101479.1 CDS Amir_3750 NC_013093.1 4407930 4408889 D PFAM: glycoside hydrolase family 43; KEGG: hypothetical protein; Arabinan endo-1,5-alpha-L-arabinosidase 4407930..4408889 Actinosynnema mirum DSM 43827 8327940 YP_003101480.1 CDS Amir_3751 NC_013093.1 4409326 4411908 D KEGG: mxa:MXAN_5281 hypothetical protein; hypothetical protein 4409326..4411908 Actinosynnema mirum DSM 43827 8327943 YP_003101481.1 CDS Amir_3752 NC_013093.1 4412999 4413424 D ECF subfamily RNA polymerase sigma-24 subunit 4412999..4413424 Actinosynnema mirum DSM 43827 8327944 YP_003101482.1 CDS Amir_3753 NC_013093.1 4413522 4414262 D hypothetical protein 4413522..4414262 Actinosynnema mirum DSM 43827 8327945 YP_003101483.1 CDS Amir_3754 NC_013093.1 4414475 4416316 R PFAM: ABC transporter transmembrane protein; ABC transporter; SMART: ATPase AAA; KEGG: scl:sce5645 carbohydrate ABC transporter; ABC transporter transmembrane protein complement(4414475..4416316) Actinosynnema mirum DSM 43827 8327946 YP_003101484.1 CDS Amir_3755 NC_013093.1 4417098 4417229 D hypothetical protein 4417098..4417229 Actinosynnema mirum DSM 43827 8327947 YP_003101485.1 CDS Amir_3756 NC_013093.1 4417761 4419506 R PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: scl:sce5644 carbohydrate ABC transporter; ABC transporter complement(4417761..4419506) Actinosynnema mirum DSM 43827 8327948 YP_003101486.1 CDS Amir_3757 NC_013093.1 4419578 4420198 D PFAM: regulatory protein TetR; KEGG: gdj:Gdia_1592 regulatory protein TetR; TetR family transcriptional regulator 4419578..4420198 Actinosynnema mirum DSM 43827 8327949 YP_003101487.1 CDS Amir_3758 NC_013093.1 4420205 4421047 R KEGG: bcz:BCZK2871 hypothetical protein; hypothetical protein complement(4420205..4421047) Actinosynnema mirum DSM 43827 8327950 YP_003101488.1 CDS Amir_3759 NC_013093.1 4421144 4421770 R hypothetical protein complement(4421144..4421770) Actinosynnema mirum DSM 43827 8327951 YP_003101489.1 CDS Amir_3761 NC_013093.1 4425066 4425890 D PFAM: Hemerythrin HHE cation binding domain protein; KEGG: dar:Daro_0364 ABC transporter; Hemerythrin HHE cation binding domain-containing protein 4425066..4425890 Actinosynnema mirum DSM 43827 8327953 YP_003101490.1 CDS Amir_3762 NC_013093.1 4425940 4427070 R PFAM: SpoOM family protein; KEGG: vha:VIBHAR_02077 hypothetical protein; SpoOM family protein complement(4425940..4427070) Actinosynnema mirum DSM 43827 8327954 YP_003101491.1 CDS Amir_3763 NC_013093.1 4427265 4427663 D PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: esa:ESA_01491 hypothetical protein; MerR family transcriptional regulator 4427265..4427663 Actinosynnema mirum DSM 43827 8327955 YP_003101492.1 CDS Amir_3764 NC_013093.1 4427736 4428965 R TIGRFAM: DGQHR domain protein; KEGG: spl:Spea_2305 hypothetical protein; DGQHR domain-containing protein complement(4427736..4428965) Actinosynnema mirum DSM 43827 8327956 YP_003101493.1 CDS Amir_3765 NC_013093.1 4429110 4429751 R hypothetical protein complement(4429110..4429751) Actinosynnema mirum DSM 43827 8327957 YP_003101494.1 CDS Amir_3766 NC_013093.1 4429822 4431537 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: afw:Anae109_0119 protein kinase; serine/threonine protein kinase complement(4429822..4431537) Actinosynnema mirum DSM 43827 8327958 YP_003101495.1 CDS Amir_3767 NC_013093.1 4431792 4432877 D TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: dac:Daci_0183 alcohol dehydrogenase; mycothiol-dependent formaldehyde dehydrogenase 4431792..4432877 Actinosynnema mirum DSM 43827 8327959 YP_003101496.1 CDS Amir_3768 NC_013093.1 4432874 4433503 D PFAM: beta-lactamase domain protein; KEGG: glo:Glov_3342 beta-lactamase domain protein; beta-lactamase domain-containing protein 4432874..4433503 Actinosynnema mirum DSM 43827 8327960 YP_003101497.1 CDS Amir_3769 NC_013093.1 4433530 4434732 R PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: sus:Acid_3087 TonB-dependent receptor; Ricin B lectin complement(4433530..4434732) Actinosynnema mirum DSM 43827 8327961 YP_003101498.1 CDS Amir_3770 NC_013093.1 4434884 4436146 D PFAM: major facilitator superfamily MFS_1; KEGG: dol:Dole_0353 major facilitator transporter; major facilitator superfamily protein 4434884..4436146 Actinosynnema mirum DSM 43827 8327962 YP_003101499.1 CDS Amir_3771 NC_013093.1 4436143 4437537 D PFAM: pyridoxal-dependent decarboxylase; aminotransferase class V; KEGG: dal:Dalk_0154 pyridoxal-dependent decarboxylase; pyridoxal-dependent decarboxylase 4436143..4437537 Actinosynnema mirum DSM 43827 8327963 YP_003101500.1 CDS Amir_3772 NC_013093.1 4437608 4438915 D KEGG: psb:Psyr_1929 hypothetical protein; hypothetical protein 4437608..4438915 Actinosynnema mirum DSM 43827 8327964 YP_003101501.1 CDS Amir_3773 NC_013093.1 4438969 4440231 R PFAM: major facilitator superfamily MFS_1; KEGG: bpd:BURPS668_A2325 major facilitator superfamily permease; major facilitator superfamily protein complement(4438969..4440231) Actinosynnema mirum DSM 43827 8327965 YP_003101502.1 CDS Amir_3774 NC_013093.1 4440361 4441194 D hypothetical protein 4440361..4441194 Actinosynnema mirum DSM 43827 8327966 YP_003101503.1 CDS Amir_3775 NC_013093.1 4441205 4441531 D hypothetical protein 4441205..4441531 Actinosynnema mirum DSM 43827 8327967 YP_003101504.1 CDS Amir_3776 NC_013093.1 4441528 4442028 D hypothetical protein 4441528..4442028 Actinosynnema mirum DSM 43827 8327968 YP_003101505.1 CDS Amir_3778 NC_013093.1 4442542 4442988 D hypothetical protein 4442542..4442988 Actinosynnema mirum DSM 43827 8327970 YP_003101506.1 CDS Amir_3779 NC_013093.1 4443040 4443453 R PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3- methyltransferase; KEGG: xca:xccb100_3974 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase complement(4443040..4443453) Actinosynnema mirum DSM 43827 8327971 YP_003101507.1 CDS Amir_3780 NC_013093.1 4443559 4443681 D hypothetical protein 4443559..4443681 Actinosynnema mirum DSM 43827 8327972 YP_003101508.1 CDS Amir_3781 NC_013093.1 4443794 4444210 R KEGG: mgm:Mmc1_3605 MJ0042 family finger-like protein; hypothetical protein complement(4443794..4444210) Actinosynnema mirum DSM 43827 8327973 YP_003101509.1 CDS Amir_3782 NC_013093.1 4444548 4444967 R hypothetical protein complement(4444548..4444967) Actinosynnema mirum DSM 43827 8327974 YP_003101510.1 CDS Amir_3783 NC_013093.1 4445068 4445277 D hypothetical protein 4445068..4445277 Actinosynnema mirum DSM 43827 8327975 YP_003101511.1 CDS Amir_3785 NC_013093.1 4445777 4446466 D hypothetical protein 4445777..4446466 Actinosynnema mirum DSM 43827 8327977 YP_003101512.1 CDS Amir_3786 NC_013093.1 4446474 4447148 R PFAM: FR47 domain protein; GCN5-related N- acetyltransferase; KEGG: swi:Swit_4396 GCN5-related N- acetyltransferase; FR47 domain-containing protein complement(4446474..4447148) Actinosynnema mirum DSM 43827 8327978 YP_003101513.1 CDS Amir_3787 NC_013093.1 4447288 4447614 D hypothetical protein 4447288..4447614 Actinosynnema mirum DSM 43827 8327979 YP_003101514.1 CDS Amir_3788 NC_013093.1 4447658 4447924 R hypothetical protein complement(4447658..4447924) Actinosynnema mirum DSM 43827 8327980 YP_003101515.1 CDS Amir_3789 NC_013093.1 4448254 4449111 R KEGG: bbr:BB0423 hydrolase; hydrolase complement(4448254..4449111) Actinosynnema mirum DSM 43827 8327981 YP_003101516.1 CDS Amir_3790 NC_013093.1 4449111 4449611 R hypothetical protein complement(4449111..4449611) Actinosynnema mirum DSM 43827 8327982 YP_003101517.1 CDS Amir_3791 NC_013093.1 4449621 4449737 R hypothetical protein complement(4449621..4449737) Actinosynnema mirum DSM 43827 8327983 YP_003101518.1 CDS Amir_3792 NC_013093.1 4450200 4451207 D KEGG: impN; serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial; hypothetical protein 4450200..4451207 Actinosynnema mirum DSM 43827 8327984 YP_003101519.1 CDS Amir_3793 NC_013093.1 4451209 4452192 D KEGG: hypothetical protein; hypothetical protein 4451209..4452192 Actinosynnema mirum DSM 43827 8327985 YP_003101520.1 CDS Amir_3794 NC_013093.1 4452176 4453609 D KEGG: rec:RHECIAT_CH0004205 adenylosuccinate synthase protein; PFAM: adenylosuccinate synthetase; SMART: adenylosuccinate synthetase; adenylosuccinate synthase 4452176..4453609 Actinosynnema mirum DSM 43827 8327986 YP_003101521.1 CDS Amir_3795 NC_013093.1 4453680 4454366 D PFAM: NUDIX hydrolase; KEGG: aeh:Mlg_0745 NUDIX hydrolase; NUDIX hydrolase 4453680..4454366 Actinosynnema mirum DSM 43827 8327987 YP_003101522.1 CDS Amir_3796 NC_013093.1 4454686 4456479 D PFAM: Ricin B lectin; glycoside hydrolase clan GH- D; SMART: Ricin B lectin; KEGG: cak:Caul_2129 alpha-galactosidase; Ricin B lectin 4454686..4456479 Actinosynnema mirum DSM 43827 8327988 YP_003101523.1 CDS Amir_3797 NC_013093.1 4456583 4456993 D KEGG: sde:Sde_1986 hypothetical protein; hypothetical protein 4456583..4456993 Actinosynnema mirum DSM 43827 8327989 YP_003101524.1 CDS Amir_3798 NC_013093.1 4457237 4458805 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin complement(4457237..4458805) Actinosynnema mirum DSM 43827 8327990 YP_003101525.1 CDS Amir_3799 NC_013093.1 4459388 4459819 D PFAM: helix-turn-helix HxlR type; KEGG: bur:Bcep18194_A4724 HxlR family transcriptional regulator; HxlR family transcriptional regulator 4459388..4459819 Actinosynnema mirum DSM 43827 8327991 YP_003101526.1 CDS Amir_3800 NC_013093.1 4460082 4461833 D PFAM: transketolase; transketolase; KEGG: tgr:Tgr7_0832 1-deoxy-D-xylulose-5-phosphate synthase; transketolase 4460082..4461833 Actinosynnema mirum DSM 43827 8327992 YP_003101527.1 CDS Amir_3801 NC_013093.1 4461830 4462822 D KEGG: scl:sce8552 terpene cyclase; hypothetical protein 4461830..4462822 Actinosynnema mirum DSM 43827 8327993 YP_003101528.1 CDS Amir_3802 NC_013093.1 4462943 4463590 D KEGG: hypothetical protein; hypothetical protein 4462943..4463590 Actinosynnema mirum DSM 43827 8327994 YP_003101529.1 CDS Amir_3804 NC_013093.1 4464116 4464541 D TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: cvi:CV_3487 hypothetical protein; BadM/Rrf2 family transcriptional regulator 4464116..4464541 Actinosynnema mirum DSM 43827 8327996 YP_003101530.1 CDS Amir_3805 NC_013093.1 4464555 4465778 D PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; globin; oxidoreductase FAD-binding domain protein; KEGG: rso:RSc3398 flavohemoprotein (hemoglobin- like) transmembrane; oxidoreductase FAD/NAD(P)-binding domain-containing protein 4464555..4465778 Actinosynnema mirum DSM 43827 8327997 YP_003101531.1 CDS Amir_3806 NC_013093.1 4465978 4466982 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: aav:Aave_2096 transcriptional regulator, ArsR family; ArsR family transcriptional regulator complement(4465978..4466982) Actinosynnema mirum DSM 43827 8327998 YP_003101532.1 CDS Amir_3807 NC_013093.1 4467254 4467676 R PFAM: Roadblock/LC7 family protein; KEGG: sml:Smlt4270 hypothetical protein; Roadblock/LC7 family protein complement(4467254..4467676) Actinosynnema mirum DSM 43827 8327999 YP_003101533.1 CDS Amir_3808 NC_013093.1 4467673 4468041 R KEGG: sml:Smlt4269 hypothetical protein; hypothetical protein complement(4467673..4468041) Actinosynnema mirum DSM 43827 8328000 YP_003101534.1 CDS Amir_3809 NC_013093.1 4468230 4469708 R TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0895 phytoene desaturase; phytoene desaturase complement(4468230..4469708) Actinosynnema mirum DSM 43827 8328001 YP_003101535.1 CDS Amir_3810 NC_013093.1 4469828 4470913 R PFAM: polyprenyl synthetase; KEGG: scl:sce4204 geranyltranstransferase; polyprenyl synthetase complement(4469828..4470913) Actinosynnema mirum DSM 43827 8328002 YP_003101536.1 CDS Amir_3811 NC_013093.1 4471084 4472016 D PFAM: squalene/phytoene synthase; KEGG: PSY; PSY (PHYTOENE SYNTHASE); geranylgeranyl- diphosphate geranylgeranyltransferase; K02291 phytoene synthase; squalene/phytoene synthase 4471084..4472016 Actinosynnema mirum DSM 43827 8328003 YP_003101537.1 CDS Amir_3812 NC_013093.1 4472135 4473112 D PFAM: Rieske [2Fe-2S] domain protein; KEGG: bur:Bcep18194_B0420 Rieske (2Fe-2S) protein; Rieske (2Fe-2S) domain-containing protein 4472135..4473112 Actinosynnema mirum DSM 43827 8328004 YP_003101538.1 CDS Amir_3813 NC_013093.1 4473221 4474792 R PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: hypothetical protein; amine oxidase complement(4473221..4474792) Actinosynnema mirum DSM 43827 8328005 YP_003101539.1 CDS Amir_3814 NC_013093.1 4474789 4475481 R PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: mno:Mnod_7055 ubiquinone/menaquinone biosynthesis methyltransferase; type 11 methyltransferase complement(4474789..4475481) Actinosynnema mirum DSM 43827 8328006 YP_003101540.1 CDS Amir_3815 NC_013093.1 4475471 4475797 R TIGRFAM: lycopene cyclase domain protein; lycopene cyclase domain-containing protein complement(4475471..4475797) Actinosynnema mirum DSM 43827 8328007 YP_003101541.1 CDS Amir_3816 NC_013093.1 4475794 4476141 R TIGRFAM: lycopene cyclase domain protein; KEGG: mxa:MXAN_0901 hypothetical protein; lycopene cyclase domain-containing protein complement(4475794..4476141) Actinosynnema mirum DSM 43827 8328008 YP_003101542.1 CDS Amir_3817 NC_013093.1 4476417 4477088 D PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: sme:SMc01715 hypothetical protein; TetR family transcriptional regulator 4476417..4477088 Actinosynnema mirum DSM 43827 8328009 YP_003101543.1 CDS Amir_3818 NC_013093.1 4477085 4478221 D PFAM: monooxygenase FAD-binding; KEGG: gdj:Gdia_2837 monooxygenase FAD-binding; FAD-binding monooxygenase 4477085..4478221 Actinosynnema mirum DSM 43827 8328010 YP_003101544.1 CDS Amir_3819 NC_013093.1 4478268 4479248 R PFAM: aldo/keto reductase; KEGG: bur:Bcep18194_B1321 aldo/keto reductase; aldo/keto reductase complement(4478268..4479248) Actinosynnema mirum DSM 43827 8328011 YP_003101545.1 CDS Amir_3820 NC_013093.1 4479361 4480224 R KEGG: hypothetical protein; hypothetical protein complement(4479361..4480224) Actinosynnema mirum DSM 43827 8328012 YP_003101546.1 CDS Amir_3821 NC_013093.1 4480366 4481229 R KEGG: calcium-binding protein; hypothetical protein complement(4480366..4481229) Actinosynnema mirum DSM 43827 8328013 YP_003101547.1 CDS Amir_3822 NC_013093.1 4481725 4485456 R PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; Cna B domain-containing protein complement(4481725..4485456) Actinosynnema mirum DSM 43827 8328014 YP_003101548.1 CDS Amir_3823 NC_013093.1 4485690 4486862 D PFAM: protein of unknown function UPF0118; KEGG: mxa:MXAN_7270 hypothetical protein; hypothetical protein 4485690..4486862 Actinosynnema mirum DSM 43827 8328015 YP_003101549.1 CDS Amir_3824 NC_013093.1 4486974 4488068 R hypothetical protein complement(4486974..4488068) Actinosynnema mirum DSM 43827 8328016 YP_003101550.1 CDS Amir_3825 NC_013093.1 4488564 4488929 R PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: bur:Bcep18194_B0126 5-carboxymethyl-2- hydroxymuconate isomerase; 5-carboxymethyl-2-hydroxymuconate isomerase complement(4488564..4488929) Actinosynnema mirum DSM 43827 8328017 YP_003101551.1 CDS Amir_3826 NC_013093.1 4489057 4489482 R TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: ajs:Ajs_3259 alkylhydroperoxidase; alkylhydroperoxidase like protein complement(4489057..4489482) Actinosynnema mirum DSM 43827 8328018 YP_003101552.1 CDS Amir_3827 NC_013093.1 4489479 4490966 R PFAM: AMP-dependent synthetase and ligase; KEGG: hch:HCH_02847 peptide arylation protein; AMP-dependent synthetase and ligase complement(4489479..4490966) Actinosynnema mirum DSM 43827 8328019 YP_003101553.1 CDS Amir_3828 NC_013093.1 4490963 4492471 R PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: nmu:Nmul_A0969 L-carnitine dehydratase/bile acid-inducible protein F; L-carnitine dehydratase/bile acid-inducible protein F complement(4490963..4492471) Actinosynnema mirum DSM 43827 8328020 YP_003101554.1 CDS Amir_3829 NC_013093.1 4492468 4493262 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: scl:sce8893 hypothetical protein; type 11 methyltransferase complement(4492468..4493262) Actinosynnema mirum DSM 43827 8328021 YP_003101555.1 CDS Amir_3830 NC_013093.1 4493303 4494838 R PFAM: AMP-dependent synthetase and ligase; KEGG: pla:Plav_1766 cyclohexanecarboxylate-CoA ligase; AMP-dependent synthetase and ligase complement(4493303..4494838) Actinosynnema mirum DSM 43827 8328022 YP_003101556.1 CDS Amir_3831 NC_013093.1 4494850 4496166 R PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cvi:CV_1653 protoporphyrinogen oxidase; amine oxidase complement(4494850..4496166) Actinosynnema mirum DSM 43827 8328023 YP_003101557.1 CDS Amir_3832 NC_013093.1 4496166 4497353 R PFAM: UbiA prenyltransferase; KEGG: hha:Hhal_1173 1,4-dihydroxy-2-naphthoate octaprenyltransferase; UbiA prenyltransferase complement(4496166..4497353) Actinosynnema mirum DSM 43827 8328024 YP_003101558.1 CDS Amir_3833 NC_013093.1 4497350 4497991 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: gur:Gura_3006 methyltransferase type 11; type 11 methyltransferase complement(4497350..4497991) Actinosynnema mirum DSM 43827 8328025 YP_003101559.1 CDS Amir_3834 NC_013093.1 4498001 4499137 R PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase complement(4498001..4499137) Actinosynnema mirum DSM 43827 8328026 YP_003101560.1 CDS Amir_3835 NC_013093.1 4499134 4500354 R PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce7344 NDP-sugar aminotransferase; glutamine--scyllo-inositol transaminase complement(4499134..4500354) Actinosynnema mirum DSM 43827 8328027 YP_003101561.1 CDS Amir_3836 NC_013093.1 4500540 4501556 D PFAM: oxidoreductase domain protein; KEGG: xac:XAC0681 oxidoreductase; oxidoreductase domain-containing protein 4500540..4501556 Actinosynnema mirum DSM 43827 8328028 YP_003101562.1 CDS Amir_3837 NC_013093.1 4501546 4502418 D PFAM: xylose isomerase; KEGG: sus:Acid_2233 xylose isomerase domain- containing protein; xylose isomerase 4501546..4502418 Actinosynnema mirum DSM 43827 8328029 YP_003101563.1 CDS Amir_3838 NC_013093.1 4502415 4503653 D PFAM: peptidase M20; KEGG: sus:Acid_2224 acetylornithine deacetylase; peptidase M20 4502415..4503653 Actinosynnema mirum DSM 43827 8328030 YP_003101564.1 CDS Amir_3839 NC_013093.1 4503650 4504738 D PFAM: malate/L-lactate dehydrogenase; KEGG: bpt:Bpet2680 malate dehydrogenase; malate/L-lactate dehydrogenase 4503650..4504738 Actinosynnema mirum DSM 43827 8328031 YP_003101565.1 CDS Amir_3840 NC_013093.1 4504939 4505904 D PFAM: oxidoreductase domain protein; KEGG: met:M446_2288 oxidoreductase domain- containing protein; oxidoreductase domain-containing protein 4504939..4505904 Actinosynnema mirum DSM 43827 8328032 YP_003101566.1 CDS Amir_3841 NC_013093.1 4505904 4506392 D hypothetical protein 4505904..4506392 Actinosynnema mirum DSM 43827 8328033 YP_003101567.1 CDS Amir_3842 NC_013093.1 4506593 4507129 R PFAM: calcium-binding EF-hand-containing protein; SMART: calcium-binding EF-hand-containing protein; KEGG: bbt:BBta_5331 calcium-binding domain- containing protein; signal transduction protein with EFhand domain complement(4506593..4507129) Actinosynnema mirum DSM 43827 8328034 YP_003101568.1 CDS Amir_3843 NC_013093.1 4507191 4508438 R TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sus:Acid_4597 UDP-glucose 6-dehydrogenase; nucleotide sugar dehydrogenase complement(4507191..4508438) Actinosynnema mirum DSM 43827 8328035 YP_003101569.1 CDS Amir_3844 NC_013093.1 4508479 4508793 R hypothetical protein complement(4508479..4508793) Actinosynnema mirum DSM 43827 8328036 YP_003101570.1 CDS Amir_3845 NC_013093.1 4509194 4510117 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mlo:mlr3236 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein complement(4509194..4510117) Actinosynnema mirum DSM 43827 8328037 YP_003101571.1 CDS Amir_3846 NC_013093.1 4510239 4510859 D PFAM: regulatory protein TetR; KEGG: scl:sce6308 TetR family transcriptional regulator; TetR family transcriptional regulator 4510239..4510859 Actinosynnema mirum DSM 43827 8328038 YP_003101572.1 CDS Amir_3847 NC_013093.1 4510911 4511951 D PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: dsh:Dshi_2951 pyridoxal-5'-phosphate- dependent protein beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit 4510911..4511951 Actinosynnema mirum DSM 43827 8328039 YP_003101573.1 CDS Amir_3848 NC_013093.1 4511982 4512608 R KEGG: mrd:Mrad2831_3526 PRC-barrel domain- containing protein; hypothetical protein complement(4511982..4512608) Actinosynnema mirum DSM 43827 8328040 YP_003101574.1 CDS Amir_3849 NC_013093.1 4512815 4516069 D TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; KEGG: cps:CPS_2650 alpha-1,2-mannosidase family protein; alpha-1,2-mannosidase 4512815..4516069 Actinosynnema mirum DSM 43827 8328041 YP_003101575.1 CDS Amir_3850 NC_013093.1 4516133 4516372 R hypothetical protein complement(4516133..4516372) Actinosynnema mirum DSM 43827 8328042 YP_003101576.1 CDS Amir_3851 NC_013093.1 4516628 4517446 D PFAM: alpha/beta hydrolase fold; KEGG: rle:RL1000 hydrolase; alpha/beta hydrolase fold protein 4516628..4517446 Actinosynnema mirum DSM 43827 8328043 YP_003101577.1 CDS Amir_3852 NC_013093.1 4517443 4518618 D KEGG: rle:RL0999 two-component regulator sensor histidine kinase protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; PAS/PAC sensor protein 4517443..4518618 Actinosynnema mirum DSM 43827 8328044 YP_003101578.1 CDS Amir_3853 NC_013093.1 4518615 4518953 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; anti-sigma-factor antagonist 4518615..4518953 Actinosynnema mirum DSM 43827 8328045 YP_003101579.1 CDS Amir_3854 NC_013093.1 4519202 4519720 D KEGG: psb:Psyr_0893 hypothetical protein; hypothetical protein 4519202..4519720 Actinosynnema mirum DSM 43827 8328046 YP_003101580.1 CDS Amir_3855 NC_013093.1 4519852 4520397 D KEGG: nha:Nham_0965 ChrB domain-containing protein; ChrB domain-containing protein 4519852..4520397 Actinosynnema mirum DSM 43827 8328047 YP_003101581.1 CDS Amir_3856 NC_013093.1 4520406 4521563 D PFAM: major facilitator superfamily MFS_1; KEGG: afw:Anae109_0137 major facilitator transporter; major facilitator superfamily protein 4520406..4521563 Actinosynnema mirum DSM 43827 8328048 YP_003101582.1 CDS Amir_3857 NC_013093.1 4521705 4522241 D TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: hne:HNE_1728 signal peptidase II; lipoprotein signal peptidase 4521705..4522241 Actinosynnema mirum DSM 43827 8328049 YP_003101583.1 CDS Amir_3858 NC_013093.1 4522255 4522710 R KEGG: rle:RL3033 hypothetical protein; hypothetical protein complement(4522255..4522710) Actinosynnema mirum DSM 43827 8328050 YP_003101584.1 CDS Amir_3859 NC_013093.1 4522751 4523536 R PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: afw:Anae109_1735 SARP family transcriptional regulator; SARP family transcriptional regulator complement(4522751..4523536) Actinosynnema mirum DSM 43827 8328051 YP_003101585.1 CDS Amir_3860 NC_013093.1 4523773 4523946 D hypothetical protein 4523773..4523946 Actinosynnema mirum DSM 43827 8328052 YP_003101586.1 CDS Amir_3861 NC_013093.1 4524018 4526471 D PFAM: Lantibiotic dehydratase domain protein; KEGG: scl:sce9070 hypothetical protein; Lantibiotic dehydratase domain-containing protein 4524018..4526471 Actinosynnema mirum DSM 43827 8328053 YP_003101587.1 CDS Amir_3862 NC_013093.1 4526468 4527556 D hypothetical protein 4526468..4527556 Actinosynnema mirum DSM 43827 8328054 YP_003101588.1 CDS Amir_3863 NC_013093.1 4527553 4529112 D KEGG: afw:Anae109_2123 heat repeat-containing PBS lyase; hypothetical protein 4527553..4529112 Actinosynnema mirum DSM 43827 8328055 YP_003101589.1 CDS Amir_3864 NC_013093.1 4529109 4530809 D PFAM: protein of unknown function DUF181; KEGG: bca:BCE_1377 hypothetical protein; hypothetical protein 4529109..4530809 Actinosynnema mirum DSM 43827 8328056 YP_003101590.1 CDS Amir_3865 NC_013093.1 4530818 4531948 D hypothetical protein 4530818..4531948 Actinosynnema mirum DSM 43827 8328057 YP_003101591.1 CDS Amir_3866 NC_013093.1 4531948 4533504 D KEGG: rsh:Rsph17029_3715 nitroreductase; hypothetical protein 4531948..4533504 Actinosynnema mirum DSM 43827 8328058 YP_003101592.1 CDS Amir_3867 NC_013093.1 4533480 4534139 R KEGG: rme:Rmet_5057 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(4533480..4534139) Actinosynnema mirum DSM 43827 8328059 YP_003101593.1 CDS Amir_3868 NC_013093.1 4534228 4535076 D KEGG: swi:Swit_4207 esterase; esterase 4534228..4535076 Actinosynnema mirum DSM 43827 8328060 YP_003101594.1 CDS Amir_3869 NC_013093.1 4535465 4536478 R KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein complement(4535465..4536478) Actinosynnema mirum DSM 43827 8328061 YP_003101595.1 CDS Amir_3870 NC_013093.1 4536619 4536849 R hypothetical protein complement(4536619..4536849) Actinosynnema mirum DSM 43827 8328062 YP_003101596.1 CDS Amir_3871 NC_013093.1 4536951 4537634 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcb:BCB4264_A5589 DNA-binding response regulator YycF; winged helix family two component transcriptional regulator complement(4536951..4537634) Actinosynnema mirum DSM 43827 8328063 YP_003101597.1 CDS Amir_3872 NC_013093.1 4537773 4538225 D KEGG: met:M446_2237 hypothetical protein; hypothetical protein 4537773..4538225 Actinosynnema mirum DSM 43827 8328064 YP_003101598.1 CDS Amir_3873 NC_013093.1 4538643 4539962 R PFAM: integrase family protein; KEGG: afw:Anae109_4219 phage integrase family protein; integrase family protein complement(4538643..4539962) Actinosynnema mirum DSM 43827 8328066 YP_003101599.1 CDS Amir_3875 NC_013093.1 4540637 4542124 R KEGG: afw:Anae109_2123 heat repeat-containing PBS lyase; hypothetical protein complement(4540637..4542124) Actinosynnema mirum DSM 43827 8328068 YP_003101600.1 CDS Amir_3876 NC_013093.1 4542333 4542443 D hypothetical protein 4542333..4542443 Actinosynnema mirum DSM 43827 8328069 YP_003101601.1 CDS Amir_3877 NC_013093.1 4542797 4543282 D hypothetical protein 4542797..4543282 Actinosynnema mirum DSM 43827 8328070 YP_003101602.1 CDS Amir_3878 NC_013093.1 4543461 4547096 D PFAM: protein of unknown function DUF312; KEGG: hso:HS_1058 large adhesin; hypothetical protein 4543461..4547096 Actinosynnema mirum DSM 43827 8328071 YP_003101603.1 CDS Amir_3879 NC_013093.1 4547854 4548399 R hypothetical protein complement(4547854..4548399) Actinosynnema mirum DSM 43827 8328072 YP_003101604.1 CDS Amir_3880 NC_013093.1 4548399 4552574 R PFAM: protein of unknown function DUF312; KEGG: hso:HS_1058 large adhesin; methyl-accepting chemotaxis sensory transducer complement(4548399..4552574) Actinosynnema mirum DSM 43827 8328073 YP_003101605.1 CDS Amir_3882 NC_013093.1 4553487 4555022 D PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap 4553487..4555022 Actinosynnema mirum DSM 43827 8328075 YP_003101606.1 CDS Amir_3883 NC_013093.1 4556416 4557636 D PFAM: condensation domain protein; KEGG: bam:Bamb_1537 amino acid adenylation domain- containing protein; condensation domain-containing protein 4556416..4557636 Actinosynnema mirum DSM 43827 8328076 YP_003101607.1 CDS Amir_3885 NC_013093.1 4558282 4558644 D KEGG: cak:Caul_1058 hypothetical protein; hypothetical protein 4558282..4558644 Actinosynnema mirum DSM 43827 8328078 YP_003101608.1 CDS Amir_3887 NC_013093.1 4559023 4560003 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ank:AnaeK_2445 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(4559023..4560003) Actinosynnema mirum DSM 43827 8328080 YP_003101609.1 CDS Amir_3888 NC_013093.1 4560100 4560663 D PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 4560100..4560663 Actinosynnema mirum DSM 43827 8328081 YP_003101610.1 CDS Amir_3890 NC_013093.1 4561320 4561814 D PFAM: peptidoglycan-binding domain 1 protein; KEGG: hypothetical protein; peptidoglycan-binding domain 1 protein 4561320..4561814 Actinosynnema mirum DSM 43827 8328083 YP_003101611.1 CDS Amir_3891 NC_013093.1 4562626 4566396 D TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: pen:PSEEN2717 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein 4562626..4566396 Actinosynnema mirum DSM 43827 8328084 YP_003101612.1 CDS Amir_3892 NC_013093.1 4566393 4574876 D TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; condensation domain protein; KR domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pen:PSEEN2718 polyketide synthase (terminal component); amino acid adenylation domain-containing protein 4566393..4574876 Actinosynnema mirum DSM 43827 8328085 YP_003101613.1 CDS Amir_3893 NC_013093.1 4574899 4575771 D PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: pen:PSEEN2720 dioxygenase, TauD; taurine dioxygenase 4574899..4575771 Actinosynnema mirum DSM 43827 8328086 YP_003101614.1 CDS Amir_3894 NC_013093.1 4575773 4576984 D PFAM: cytochrome P450; KEGG: scl:sce7167 hypothetical protein; cytochrome P450 4575773..4576984 Actinosynnema mirum DSM 43827 8328087 YP_003101615.1 CDS Amir_3895 NC_013093.1 4576981 4577658 D KEGG: mes:Meso_2739 UDP-glucose pyrophosphorylase; hypothetical protein 4576981..4577658 Actinosynnema mirum DSM 43827 8328088 YP_003101616.1 CDS Amir_3896 NC_013093.1 4577661 4579112 D PFAM: beta-lactamase; KEGG: xac:XAC0134 beta-lactamase; beta-lactamase 4577661..4579112 Actinosynnema mirum DSM 43827 8328089 YP_003101617.1 CDS Amir_3897 NC_013093.1 4579109 4580302 D PFAM: glycosyl transferase family 28; KEGG: scl:sce8970 glycosyl transferase; glycosyl transferase family protein 4579109..4580302 Actinosynnema mirum DSM 43827 8328090 YP_003101618.1 CDS Amir_3898 NC_013093.1 4580448 4580888 D hypothetical protein 4580448..4580888 Actinosynnema mirum DSM 43827 8328091 YP_003101619.1 CDS Amir_3899 NC_013093.1 4580932 4581795 R PFAM: NmrA family protein; KEGG: scl:sce1557 hypothetical protein; NmrA family protein complement(4580932..4581795) Actinosynnema mirum DSM 43827 8328092 YP_003101620.1 CDS Amir_3900 NC_013093.1 4581892 4582767 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bma:BMAA0201 transcriptional regulator CatR; LysR family transcriptional regulator 4581892..4582767 Actinosynnema mirum DSM 43827 8328093 YP_003101621.1 CDS Amir_3901 NC_013093.1 4582820 4583005 R hypothetical protein complement(4582820..4583005) Actinosynnema mirum DSM 43827 8328094 YP_003101622.1 CDS Amir_3902 NC_013093.1 4583361 4583861 R PFAM: cupin; KEGG: hypothetical protein; cupin complement(4583361..4583861) Actinosynnema mirum DSM 43827 8328095 YP_003101623.1 CDS Amir_3903 NC_013093.1 4583907 4584851 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: rme:Rmet_4293 alcohol dehydrogenase, zinc- binding; alcohol dehydrogenase GroES domain-containing protein complement(4583907..4584851) Actinosynnema mirum DSM 43827 8328096 YP_003101624.1 CDS Amir_3904 NC_013093.1 4585012 4585866 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcj:BCAM0680 DNA-binding protein; XRE family transcriptional regulator complement(4585012..4585866) Actinosynnema mirum DSM 43827 8328097 YP_003101625.1 CDS Amir_3905 NC_013093.1 4585944 4586396 R hypothetical protein complement(4585944..4586396) Actinosynnema mirum DSM 43827 8328098 YP_003101626.1 CDS Amir_3906 NC_013093.1 4586393 4586659 R KEGG: hypothetical protein; hypothetical protein complement(4586393..4586659) Actinosynnema mirum DSM 43827 8328099 YP_003101627.1 CDS Amir_3907 NC_013093.1 4587082 4587972 D PFAM: glycoside hydrolase family 18; KEGG: hypothetical protein; mannosyl-glycoproteinendo-beta-N-acetylglucosami nidase 4587082..4587972 Actinosynnema mirum DSM 43827 8328100 YP_003101628.1 CDS Amir_3911 NC_013093.1 4590595 4591464 D PFAM: transport system permease protein; KEGG: pmy:Pmen_4564 transport system permease protein; transport system permease 4590595..4591464 Actinosynnema mirum DSM 43827 8328104 YP_003101629.1 CDS Amir_3912 NC_013093.1 4591490 4592509 D PFAM: periplasmic binding protein; KEGG: pen:PSEEN3067 Fe uptake ABC transporter, periplasmic binding protein; periplasmic binding protein 4591490..4592509 Actinosynnema mirum DSM 43827 8328105 YP_003101630.1 CDS Amir_3913 NC_013093.1 4592616 4593392 R PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: pau:PA14_39660 hypothetical protein; type 12 methyltransferase complement(4592616..4593392) Actinosynnema mirum DSM 43827 8328106 YP_003101631.1 CDS Amir_3914 NC_013093.1 4593389 4594213 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pmy:Pmen_4566 ABC transporter; ABC transporter complement(4593389..4594213) Actinosynnema mirum DSM 43827 8328107 YP_003101632.1 CDS Amir_3915 NC_013093.1 4594210 4595292 R PFAM: transport system permease protein; KEGG: dac:Daci_3791 transport system permease protein; transport system permease complement(4594210..4595292) Actinosynnema mirum DSM 43827 8328108 YP_003101633.1 CDS Amir_3916 NC_013093.1 4595289 4596419 R PFAM: periplasmic binding protein; KEGG: bpm:BURPS1710b_3208 periplasmic binding protein; periplasmic binding protein complement(4595289..4596419) Actinosynnema mirum DSM 43827 8328109 YP_003101634.1 CDS Amir_3917 NC_013093.1 4596416 4597690 R PFAM: major facilitator superfamily MFS_1; KEGG: dsh:Dshi_2354 major facilitator transporter; major facilitator superfamily protein complement(4596416..4597690) Actinosynnema mirum DSM 43827 8328110 YP_003101635.1 CDS Amir_3918 NC_013093.1 4597687 4598985 R KEGG: bha:BH2073 hypothetical protein; hypothetical protein complement(4597687..4598985) Actinosynnema mirum DSM 43827 8328111 YP_003101636.1 CDS Amir_3919 NC_013093.1 4599030 4599821 R KEGG: bha:BH2072 hypothetical protein; hypothetical protein complement(4599030..4599821) Actinosynnema mirum DSM 43827 8328112 YP_003101637.1 CDS Amir_3920 NC_013093.1 4599882 4600694 R KEGG: bha:BH2071 hypothetical protein; hypothetical protein complement(4599882..4600694) Actinosynnema mirum DSM 43827 8328113 YP_003101638.1 CDS Amir_3921 NC_013093.1 4600924 4601322 R hypothetical protein complement(4600924..4601322) Actinosynnema mirum DSM 43827 8328114 YP_003101639.1 CDS Amir_3922 NC_013093.1 4601669 4602676 D KEGG: rso:RS03054 hypothetical protein; hypothetical protein 4601669..4602676 Actinosynnema mirum DSM 43827 8328115 YP_003101640.1 CDS Amir_3923 NC_013093.1 4602815 4604995 D KEGG: bpy:Bphyt_0257 hypothetical protein; hypothetical protein 4602815..4604995 Actinosynnema mirum DSM 43827 8328116 YP_003101641.1 CDS Amir_3924 NC_013093.1 4605007 4606827 D PFAM: carbamoyltransferase; KEGG: bpy:Bphyt_0258 carbamoyltransferase; carbamoyltransferase 4605007..4606827 Actinosynnema mirum DSM 43827 8328117 YP_003101642.1 CDS Amir_3926 NC_013093.1 4606993 4608054 R PFAM: glycoside hydrolase family 43; KEGG: cja:CJA_0819 alpha-L-arabinfuranosidase, , abf43M; alpha-N-arabinofuranosidase complement(4606993..4608054) Actinosynnema mirum DSM 43827 8328119 YP_003101643.1 CDS Amir_3927 NC_013093.1 4608144 4609454 R PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: sde:Sde_3710 arabinogalactan endo-1,4-beta- galactosidase; Ricin B lectin complement(4608144..4609454) Actinosynnema mirum DSM 43827 8328120 YP_003101644.1 CDS Amir_3929 NC_013093.1 4610870 4612102 D PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: mfa:Mfla_0439 aminomethyltransferase; glycine cleavage T protein (aminomethyl transferase) 4610870..4612102 Actinosynnema mirum DSM 43827 8328122 YP_003101645.1 CDS Amir_3930 NC_013093.1 4612099 4613166 D PFAM: FAD dependent oxidoreductase; KEGG: sus:Acid_5898 N-methyltryptophan oxidase; FAD dependent oxidoreductase 4612099..4613166 Actinosynnema mirum DSM 43827 8328123 YP_003101646.1 CDS Amir_3931 NC_013093.1 4613163 4614155 D PFAM: aldo/keto reductase; KEGG: gur:Gura_3526 aldo/keto reductase; aldo/keto reductase 4613163..4614155 Actinosynnema mirum DSM 43827 8328124 YP_003101647.1 CDS Amir_3932 NC_013093.1 4614163 4614450 D hypothetical protein 4614163..4614450 Actinosynnema mirum DSM 43827 8328125 YP_003101648.1 CDS Amir_3933 NC_013093.1 4614478 4616217 D PFAM: carbamoyltransferase; KEGG: nha:Nham_2127 carbamoyltransferase; carbamoyltransferase 4614478..4616217 Actinosynnema mirum DSM 43827 8328126 YP_003101649.1 CDS Amir_3934 NC_013093.1 4616214 4616993 D PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: tbd:Tbd_2162 hypothetical protein; type 11 methyltransferase 4616214..4616993 Actinosynnema mirum DSM 43827 8328127 YP_003101650.1 CDS Amir_3935 NC_013093.1 4616995 4618212 D PFAM: major facilitator superfamily MFS_1; KEGG: ppu:PP_3961 major facilitator transporter; major facilitator superfamily protein 4616995..4618212 Actinosynnema mirum DSM 43827 8328128 YP_003101651.1 CDS Amir_3938 NC_013093.1 4619639 4620379 D hypothetical protein 4619639..4620379 Actinosynnema mirum DSM 43827 8328131 YP_003101652.1 CDS Amir_3939 NC_013093.1 4620663 4621283 R PFAM: bifunctional deaminase-reductase domain protein; KEGG: cvi:CV_3295 hypothetical protein; bifunctional deaminase-reductase domain-containing protein complement(4620663..4621283) Actinosynnema mirum DSM 43827 8328132 YP_003101653.1 CDS Amir_3940 NC_013093.1 4621283 4621861 R PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: afw:Anae109_0511 activator of HSP90 ATPase 1 family protein; Activator of Hsp90 ATPase 1 family protein complement(4621283..4621861) Actinosynnema mirum DSM 43827 8328133 YP_003101654.1 CDS Amir_3941 NC_013093.1 4621865 4622206 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: afw:Anae109_0512 regulatory protein ArsR; ArsR family transcriptional regulator complement(4621865..4622206) Actinosynnema mirum DSM 43827 8328134 YP_003101655.1 CDS Amir_3942 NC_013093.1 4622296 4622889 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ent:Ent638_3529 XRE family transcriptional regulator; XRE family transcriptional regulator complement(4622296..4622889) Actinosynnema mirum DSM 43827 8328135 YP_003101656.1 CDS Amir_3943 NC_013093.1 4622991 4624229 D PFAM: major facilitator superfamily MFS_1; KEGG: smd:Smed_5551 hypothetical protein; major facilitator superfamily protein 4622991..4624229 Actinosynnema mirum DSM 43827 8328136 YP_003101657.1 CDS Amir_3944 NC_013093.1 4624226 4625626 R KEGG: sde:Sde_0791 alpha-L-arabinofuranosidase; PFAM: glycoside hydrolase family 43; Ricin B lectin; SMART: Ricin B lectin; alpha-N-arabinofuranosidase complement(4624226..4625626) Actinosynnema mirum DSM 43827 8328137 YP_003101658.1 CDS Amir_3945 NC_013093.1 4625812 4626699 D PFAM: aldo/keto reductase; KEGG: mes:Meso_3900 aldo/keto reductase; aldo/keto reductase 4625812..4626699 Actinosynnema mirum DSM 43827 8328138 YP_003101659.1 CDS Amir_3946 NC_013093.1 4626914 4627252 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sus:Acid_5261 anti-sigma-factor antagonist; anti-sigma-factor antagonist 4626914..4627252 Actinosynnema mirum DSM 43827 8328139 YP_003101660.1 CDS Amir_3947 NC_013093.1 4627327 4628079 R PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: acp:A2cp1_0906 transcriptional regulator, LuxR family; LuxR family transcriptional regulator complement(4627327..4628079) Actinosynnema mirum DSM 43827 8328140 YP_003101661.1 CDS Amir_3948 NC_013093.1 4628751 4630325 R TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bph:Bphy_3357 EmrB/QacA family drug resistance transporter; EmrB/QacA subfamily drug resistance transporter complement(4628751..4630325) Actinosynnema mirum DSM 43827 8328141 YP_003101662.1 CDS Amir_3949 NC_013093.1 4630322 4630954 R PFAM: regulatory protein TetR; KEGG: transcriptional regulator protein; TetR family transcriptional regulator complement(4630322..4630954) Actinosynnema mirum DSM 43827 8328142 YP_003101663.1 CDS Amir_3950 NC_013093.1 4631056 4631766 R KEGG: acp:A2cp1_0909 translation initiation factor SUI1; hypothetical protein complement(4631056..4631766) Actinosynnema mirum DSM 43827 8328143 YP_003101664.1 CDS Amir_3951 NC_013093.1 4631763 4632101 R hypothetical protein complement(4631763..4632101) Actinosynnema mirum DSM 43827 8328144 YP_003101665.1 CDS Amir_3952 NC_013093.1 4632114 4633286 R KEGG: YALI0E33891p; hypothetical protein complement(4632114..4633286) Actinosynnema mirum DSM 43827 8328145 YP_003101666.1 CDS Amir_3953 NC_013093.1 4633430 4633744 R PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: azc:AZC_4213 anti-sigma factor antagonist; anti-sigma-factor antagonist complement(4633430..4633744) Actinosynnema mirum DSM 43827 8328146 YP_003101667.1 CDS Amir_3954 NC_013093.1 4633741 4637853 R KEGG: cti:RALTA_B0128 multi-site sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein; multi-sensor signal transduction histidine kinase complement(4633741..4637853) Actinosynnema mirum DSM 43827 8328147 YP_003101668.1 CDS Amir_3955 NC_013093.1 4637943 4638350 R PFAM: ATP-binding region ATPase domain protein; ATP-binding region ATPase domain-containing protein complement(4637943..4638350) Actinosynnema mirum DSM 43827 8328148 YP_003101669.1 CDS Amir_3956 NC_013093.1 4638618 4639436 D KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein 4638618..4639436 Actinosynnema mirum DSM 43827 8328149 YP_003101670.1 CDS Amir_3957 NC_013093.1 4639751 4640620 D PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; cyclic nucleotide- binding; KEGG: swi:Swit_2706 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 4639751..4640620 Actinosynnema mirum DSM 43827 8328150 YP_003101671.1 CDS Amir_3958 NC_013093.1 4640945 4642042 R PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; KEGG: sde:Sde_0943 ribosomal protein S5; pectate lyase/Amb allergen complement(4640945..4642042) Actinosynnema mirum DSM 43827 8328151 YP_003101672.1 CDS Amir_3959 NC_013093.1 4642382 4643653 R KEGG: acetyl xylan esterase; K01567; TIGRFAM: esterase, PHB depolymerase family; PFAM: cellulose-binding family II; SMART: cellulose-binding family II; esterase, PHB depolymerase family complement(4642382..4643653) Actinosynnema mirum DSM 43827 8328152 YP_003101673.1 CDS Amir_3960 NC_013093.1 4643730 4644617 R KEGG: vvu:VV2_0700 beta-lactamase class A; hypothetical protein complement(4643730..4644617) Actinosynnema mirum DSM 43827 8328153 YP_003101674.1 CDS Amir_3961 NC_013093.1 4644629 4645495 R PFAM: regulatory protein LysR; KEGG: bmj:BMULJ_04428 LysR family transcriptional regulator; LysR family transcriptional regulator complement(4644629..4645495) Actinosynnema mirum DSM 43827 8328154 YP_003101675.1 CDS Amir_3962 NC_013093.1 4645608 4646555 D PFAM: beta-lactamase; penicillin-binding protein transpeptidase; KEGG: bsu:BSU18800 beta-lactamase precursor; beta-lactamase 4645608..4646555 Actinosynnema mirum DSM 43827 8328155 YP_003101676.1 CDS Amir_3963 NC_013093.1 4646925 4647869 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sml:Smlt2229 hypothetical protein; XRE family transcriptional regulator complement(4646925..4647869) Actinosynnema mirum DSM 43827 8328156 YP_003101677.1 CDS Amir_3964 NC_013093.1 4648428 4649474 D PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: sme:SMc00680 zinc-type alcohol dehydrogenase protein; alcohol dehydrogenase GroES domain-containing protein 4648428..4649474 Actinosynnema mirum DSM 43827 8328157 YP_003101678.1 CDS Amir_3966 NC_013093.1 4649883 4650263 D hypothetical protein 4649883..4650263 Actinosynnema mirum DSM 43827 8328159 YP_003101679.1 CDS Amir_3967 NC_013093.1 4650450 4650869 R KEGG: dac:Daci_4779 SPW repeat-containing protein; hypothetical protein complement(4650450..4650869) Actinosynnema mirum DSM 43827 8328160 YP_003101680.1 CDS Amir_3968 NC_013093.1 4651137 4652510 D KEGG: scl:sce6003 protein kinase; hypothetical protein 4651137..4652510 Actinosynnema mirum DSM 43827 8328161 YP_003101681.1 CDS Amir_3969 NC_013093.1 4652552 4652980 R hypothetical protein complement(4652552..4652980) Actinosynnema mirum DSM 43827 8328162 YP_003101682.1 CDS Amir_3971 NC_013093.1 4653718 4655205 R PFAM: pyrrolo-quinoline quinone; SMART: pyrrolo-quinoline quinone; KEGG: rso:RSc1218 lipoprotein transmembrane; pyrrolo-quinoline quinone complement(4653718..4655205) Actinosynnema mirum DSM 43827 8328164 YP_003101683.1 CDS Amir_3972 NC_013093.1 4655564 4656814 D PFAM: monooxygenase FAD-binding; KEGG: pde:Pden_1503 hypothetical protein; FAD-binding monooxygenase 4655564..4656814 Actinosynnema mirum DSM 43827 8328165 YP_003101684.1 CDS Amir_3973 NC_013093.1 4656811 4658328 R PFAM: extracellular solute-binding protein family 5; KEGG: ABC-type dipeptide transport system, periplasmic component; K02035 peptide/nickel transport system substrate-binding protein; family 5 extracellular solute-binding protein complement(4656811..4658328) Actinosynnema mirum DSM 43827 8328166 YP_003101685.1 CDS Amir_3974 NC_013093.1 4658604 4659263 R Represses a number of genes involved in the response to DNA damage; LexA repressor complement(4658604..4659263) Actinosynnema mirum DSM 43827 8328167 YP_003101686.1 CDS Amir_3975 NC_013093.1 4659383 4659994 D PFAM: regulatory protein TetR; KEGG: bja:bll7174 transcriptional regulatory protein; TetR family transcriptional regulator 4659383..4659994 Actinosynnema mirum DSM 43827 8328168 YP_003101687.1 CDS Amir_3976 NC_013093.1 4660107 4660841 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bpy:Bphyt_1098 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4660107..4660841 Actinosynnema mirum DSM 43827 8328169 YP_003101688.1 CDS Amir_3977 NC_013093.1 4660957 4661259 D KEGG: hypothetical protein; hypothetical protein 4660957..4661259 Actinosynnema mirum DSM 43827 8328170 YP_003101689.1 CDS Amir_3978 NC_013093.1 4661377 4662579 R PFAM: major facilitator superfamily MFS_1; KEGG: mxa:MXAN_2233 major facilitator family transporter; major facilitator superfamily protein complement(4661377..4662579) Actinosynnema mirum DSM 43827 8328171 YP_003101690.1 CDS Amir_3979 NC_013093.1 4662650 4663261 D PFAM: regulatory protein TetR; KEGG: mrd:Mrad2831_1768 TetR family transcriptional regulator; TetR family transcriptional regulator 4662650..4663261 Actinosynnema mirum DSM 43827 8328172 YP_003101691.1 CDS ribA NC_013093.1 4663413 4664120 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 4663413..4664120 Actinosynnema mirum DSM 43827 8328173 YP_003101692.1 CDS Amir_3981 NC_013093.1 4664117 4664719 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: oan:Oant_4026 transcriptional regulator, MarR family; MarR family transcriptional regulator 4664117..4664719 Actinosynnema mirum DSM 43827 8328174 YP_003101693.1 CDS Amir_3982 NC_013093.1 4664740 4665765 D TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; KEGG: xca:xccb100_3664 riboflavin biosynthesis protein RibD (diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-[5-phosphoribosylamino]uracil reductase); riboflavin biosynthesis protein RibD 4664740..4665765 Actinosynnema mirum DSM 43827 8328175 YP_003101694.1 CDS Amir_3983 NC_013093.1 4665992 4667137 D PFAM: peptidase dimerization domain protein; peptidase M20; KEGG: aba:Acid345_0237 peptidase M20; peptidase dimerization domain-containing protein 4665992..4667137 Actinosynnema mirum DSM 43827 8328176 YP_003101695.1 CDS Amir_3984 NC_013093.1 4667269 4669086 D PFAM: PBS lyase HEAT domain protein repeat- containing protein; HEAT domain containing protein; SMART: PBS lyase HEAT domain protein repeat- containing protein; KEGG: afw:Anae109_2123 heat repeat-containing PBS lyase; PBS lyase HEAT domain-containing protein repeat-containing protein 4667269..4669086 Actinosynnema mirum DSM 43827 8328177 YP_003101696.1 CDS Amir_3985 NC_013093.1 4669083 4669709 D KEGG: hypothetical protein LOC100014234; hypothetical protein 4669083..4669709 Actinosynnema mirum DSM 43827 8328178 YP_003101697.1 CDS Amir_3986 NC_013093.1 4669702 4670595 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xcv:XCV1204 oxidoreductase; short-chain dehydrogenase/reductase SDR complement(4669702..4670595) Actinosynnema mirum DSM 43827 8328179 YP_003101698.1 CDS Amir_3987 NC_013093.1 4670740 4671501 R PFAM: glycoside hydrolase family 12; KEGG: hypothetical protein; glycoside hydrolase family protein complement(4670740..4671501) Actinosynnema mirum DSM 43827 8328180 YP_003101699.1 CDS Amir_3988 NC_013093.1 4671675 4672532 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: psb:Psyr_0904 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(4671675..4672532) Actinosynnema mirum DSM 43827 8328181 YP_003101700.1 CDS Amir_3989 NC_013093.1 4672872 4673924 D KEGG: tgr:Tgr7_0702 glutathione S- transferase; glutathione S-transferase 4672872..4673924 Actinosynnema mirum DSM 43827 8328182 YP_003101701.1 CDS Amir_3990 NC_013093.1 4673944 4674690 D PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: atc:AGR_pAT_269 hypothetical protein; MerR family transcriptional regulator 4673944..4674690 Actinosynnema mirum DSM 43827 8328183 YP_003101702.1 CDS Amir_3992 NC_013093.1 4676336 4677082 D PFAM: NmrA family protein; dTDP-4-dehydrorhamnose reductase; KEGG: bpa:BPP3249 hypothetical protein; NmrA family protein 4676336..4677082 Actinosynnema mirum DSM 43827 8328185 YP_003101703.1 CDS Amir_3993 NC_013093.1 4677058 4677591 R PFAM: hypothetical protein; KEGG: mlo:mll8365 hypothetical protein; hypothetical protein complement(4677058..4677591) Actinosynnema mirum DSM 43827 8328186 YP_003101704.1 CDS Amir_3994 NC_013093.1 4677708 4679381 D PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein 4677708..4679381 Actinosynnema mirum DSM 43827 8328187 YP_003101705.1 CDS Amir_3995 NC_013093.1 4679427 4679972 R KEGG: rpb:RPB_1369 hypothetical protein; hypothetical protein complement(4679427..4679972) Actinosynnema mirum DSM 43827 8328188 YP_003101706.1 CDS Amir_3996 NC_013093.1 4679977 4680414 R KEGG: ank:AnaeK_1205 protein of unknown function DUF1028; hypothetical protein complement(4679977..4680414) Actinosynnema mirum DSM 43827 8328189 YP_003101707.1 CDS Amir_3997 NC_013093.1 4680580 4681461 D PFAM: SEFIR domain protein; KEGG: gme:Gmet_1793 hypothetical protein; SEFIR domain-containing protein 4680580..4681461 Actinosynnema mirum DSM 43827 8328190 YP_003101708.1 CDS Amir_3998 NC_013093.1 4681533 4681718 D hypothetical protein 4681533..4681718 Actinosynnema mirum DSM 43827 8328191 YP_003101709.1 CDS Amir_3999 NC_013093.1 4681806 4682201 D KEGG: nwi:Nwi_1916 hypothetical protein; hypothetical protein 4681806..4682201 Actinosynnema mirum DSM 43827 8328192 YP_003101710.1 CDS Amir_4000 NC_013093.1 4682227 4683372 D PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 4682227..4683372 Actinosynnema mirum DSM 43827 8328193 YP_003101711.1 CDS Amir_4001 NC_013093.1 4683398 4684051 D PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 4683398..4684051 Actinosynnema mirum DSM 43827 8328194 YP_003101712.1 CDS Amir_4002 NC_013093.1 4684166 4684633 D hypothetical protein 4684166..4684633 Actinosynnema mirum DSM 43827 8328195 YP_003101713.1 CDS Amir_4003 NC_013093.1 4684882 4685634 D PFAM: Thioesterase; KEGG: pau:PA14_09230 pyochelin biosynthetic protein PchC; oleoyl-(acyl-carrier-protein) hydrolase 4684882..4685634 Actinosynnema mirum DSM 43827 8328196 YP_003101714.1 CDS Amir_4004 NC_013093.1 4685708 4686625 R KEGG: hypothetical protein; hypothetical protein complement(4685708..4686625) Actinosynnema mirum DSM 43827 8328197 YP_003101715.1 CDS Amir_4005 NC_013093.1 4686747 4687937 D PFAM: monooxygenase FAD-binding; KEGG: msl:Msil_0387 monooxygenase FAD-binding; FAD-binding monooxygenase 4686747..4687937 Actinosynnema mirum DSM 43827 8328198 YP_003101716.1 CDS Amir_4006 NC_013093.1 4687988 4688569 R PFAM: regulatory protein TetR; KEGG: acp:A2cp1_2482 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(4687988..4688569) Actinosynnema mirum DSM 43827 8328199 YP_003101717.1 CDS Amir_4007 NC_013093.1 4688647 4689456 R PFAM: xylose isomerase; KEGG: smd:Smed_3334 xylose isomerase domain protein TIM barrel; xylose isomerase complement(4688647..4689456) Actinosynnema mirum DSM 43827 8328200 YP_003101718.1 CDS Amir_4008 NC_013093.1 4689453 4690595 R KEGG: sme:SMc04132 hypothetical protein; hypothetical protein complement(4689453..4690595) Actinosynnema mirum DSM 43827 8328201 YP_003101719.1 CDS Amir_4009 NC_013093.1 4690592 4691737 R PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: atc:AGR_L_3386 hypothetical protein; oxidoreductase domain-containing protein complement(4690592..4691737) Actinosynnema mirum DSM 43827 8328202 YP_003101720.1 CDS Amir_4011 NC_013093.1 4693102 4693743 R PFAM: superoxide dismutase copper/zinc binding; superoxide dismutase copper/zinc binding complement(4693102..4693743) Actinosynnema mirum DSM 43827 8328204 YP_003101721.1 CDS Amir_4012 NC_013093.1 4693917 4695188 D KEGG: rlt:Rleg2_2895 heat domain containing protein; heat domain containing protein 4693917..4695188 Actinosynnema mirum DSM 43827 8328205 YP_003101722.1 CDS Amir_4013 NC_013093.1 4695762 4696562 D PFAM: alpha/beta hydrolase fold; KEGG: pde:Pden_1042 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4695762..4696562 Actinosynnema mirum DSM 43827 8328206 YP_003101723.1 CDS Amir_4014 NC_013093.1 4696610 4697110 R PFAM: transcriptional regulator domain protein; KEGG: bcb:BCB4264_A1351 DNA-binding response regulator; winged helix family two component transcriptional regulator complement(4696610..4697110) Actinosynnema mirum DSM 43827 8328207 YP_003101724.1 CDS Amir_4015 NC_013093.1 4697316 4698173 D PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: sde:Sde_1920 methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NADP(+)) 4697316..4698173 Actinosynnema mirum DSM 43827 8328208 YP_003101725.1 CDS Amir_4016 NC_013093.1 4698370 4699722 R KEGG: sus:Acid_5487 O-acetylhomoserine/O- acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; O-acetylhomoserine/O-acetylserine sulfhydrylase complement(4698370..4699722) Actinosynnema mirum DSM 43827 8328209 YP_003101726.1 CDS Amir_4017 NC_013093.1 4699865 4700668 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bbt:BBta_7223 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(4699865..4700668) Actinosynnema mirum DSM 43827 8328210 YP_003101727.1 CDS Amir_4018 NC_013093.1 4701286 4701927 R KEGG: jan:Jann_0393 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(4701286..4701927) Actinosynnema mirum DSM 43827 8328211 YP_003101728.1 CDS Amir_4019 NC_013093.1 4702898 4719478 D PFAM: acyl transferase; beta-ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I; acyl transferase 4702898..4719478 Actinosynnema mirum DSM 43827 8328212 YP_003101729.1 CDS Amir_4020 NC_013093.1 4719491 4720342 R PFAM: luciferase-like monooxygenase; KEGG: oca:OCAR_4999 hypothetical protein; luciferase-like monooxygenase complement(4719491..4720342) Actinosynnema mirum DSM 43827 8328213 YP_003101730.1 CDS Amir_4021 NC_013093.1 4720433 4721644 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: dde:Dde_2559 beta-N-acetylhexosaminidase; glycoside hydrolase family protein complement(4720433..4721644) Actinosynnema mirum DSM 43827 8328214 YP_003101731.1 CDS Amir_4022 NC_013093.1 4722188 4724440 D KEGG: acp:A2cp1_0462 exonuclease SbcC; hypothetical protein 4722188..4724440 Actinosynnema mirum DSM 43827 8328215 YP_003101732.1 CDS Amir_4023 NC_013093.1 4724509 4725687 D hypothetical protein 4724509..4725687 Actinosynnema mirum DSM 43827 8328216 YP_003101733.1 CDS Amir_4024 NC_013093.1 4725938 4726183 D hypothetical protein 4725938..4726183 Actinosynnema mirum DSM 43827 8328217 YP_003101734.1 CDS Amir_4025 NC_013093.1 4726180 4726443 D hypothetical protein 4726180..4726443 Actinosynnema mirum DSM 43827 8328218 YP_003101735.1 CDS Amir_4026 NC_013093.1 4726467 4726778 R hypothetical protein complement(4726467..4726778) Actinosynnema mirum DSM 43827 8328219 YP_003101736.1 CDS Amir_4027 NC_013093.1 4726953 4727339 D hypothetical protein 4726953..4727339 Actinosynnema mirum DSM 43827 8328220 YP_003101737.1 CDS Amir_4028 NC_013093.1 4727392 4728873 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: sus:Acid_7020 WD-40 repeat-containing serine/threonin protein kinase; serine/threonine protein kinase complement(4727392..4728873) Actinosynnema mirum DSM 43827 8328221 YP_003101738.1 CDS Amir_4029 NC_013093.1 4729017 4731491 R KEGG: rle:pRL90161 hypothetical protein; hypothetical protein complement(4729017..4731491) Actinosynnema mirum DSM 43827 8328222 YP_003101739.1 CDS Amir_4030 NC_013093.1 4731947 4732843 D KEGG: bba:Bd3647 hypothetical protein; hypothetical protein 4731947..4732843 Actinosynnema mirum DSM 43827 8328223 YP_003101740.1 CDS Amir_4031 NC_013093.1 4733014 4734609 R KEGG: hypothetical protein; PFAM: Ricin B lectin; SMART: Ricin B lectin; glucan endo-1,3-beta-D-glucosidase complement(4733014..4734609) Actinosynnema mirum DSM 43827 8328224 YP_003101741.1 CDS Amir_4032 NC_013093.1 4734902 4736407 R PFAM: AMP-dependent synthetase and ligase; KEGG: vei:Veis_4674 acyl-CoA synthetase; AMP-dependent synthetase and ligase complement(4734902..4736407) Actinosynnema mirum DSM 43827 8328225 YP_003101742.1 CDS Amir_4033 NC_013093.1 4736646 4738229 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: RCJMB04_10a6, FOXRED2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4736646..4738229 Actinosynnema mirum DSM 43827 8328226 YP_003101743.1 CDS Amir_4034 NC_013093.1 4738226 4739347 D PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: scl:sce7671 (S)-2-hydroxy-acid oxidase; FMN-dependent alpha-hydroxy acid dehydrogenase 4738226..4739347 Actinosynnema mirum DSM 43827 8328227 YP_003101744.1 CDS Amir_4035 NC_013093.1 4739344 4740780 D KEGG: predicted protein; cytochrome P450-like protein 4739344..4740780 Actinosynnema mirum DSM 43827 8328228 YP_003101745.1 CDS Amir_4036 NC_013093.1 4741043 4742311 D PFAM: sodium/hydrogen exchanger; KEGG: pzu:PHZ_c2901 Kef-type K+ transport system, membrane component; sodium/hydrogen exchanger 4741043..4742311 Actinosynnema mirum DSM 43827 8328229 YP_003101746.1 CDS Amir_4038 NC_013093.1 4742888 4744243 D PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: histidine kinase; histidine kinase 4742888..4744243 Actinosynnema mirum DSM 43827 8328231 YP_003101747.1 CDS Amir_4039 NC_013093.1 4744828 4745112 D KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein 4744828..4745112 Actinosynnema mirum DSM 43827 8328232 YP_003101748.1 CDS Amir_4040 NC_013093.1 4745429 4745929 R KEGG: asa:ASA_3456 hypothetical protein; hypothetical protein complement(4745429..4745929) Actinosynnema mirum DSM 43827 8328233 YP_003101749.1 CDS Amir_4041 NC_013093.1 4746067 4751058 R KEGG: ade:Adeh_3797 hypothetical protein; hypothetical protein complement(4746067..4751058) Actinosynnema mirum DSM 43827 8328234 YP_003101750.1 CDS Amir_4042 NC_013093.1 4751173 4752312 R PFAM: mandelate racemase/muconate lactonizing protein; KEGG: reu:Reut_B4643 mandelate racemase/muconate lactonizing protein; mandelate racemase/muconate lactonizing protein complement(4751173..4752312) Actinosynnema mirum DSM 43827 8328235 YP_003101751.1 CDS Amir_4044 NC_013093.1 4753130 4755073 D PFAM: Na-Ca exchanger/integrin-beta4; SMART: Na-Ca exchanger/integrin-beta4; KEGG: hch:HCH_05909 hypothetical protein; Na-Ca exchanger/integrin-beta4 4753130..4755073 Actinosynnema mirum DSM 43827 8328237 YP_003101752.1 CDS Amir_4045 NC_013093.1 4755135 4756883 R PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rru:Rru_A2339 ABC transporter component; ABC transporter complement(4755135..4756883) Actinosynnema mirum DSM 43827 8328238 YP_003101753.1 CDS Amir_4046 NC_013093.1 4756880 4758670 R PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: rru:Rru_A2340 ABC transporter, transmembrane region; ABC transporter complement(4756880..4758670) Actinosynnema mirum DSM 43827 8328239 YP_003101754.1 CDS Amir_4047 NC_013093.1 4758797 4759492 R PFAM: regulatory protein TetR; KEGG: mlo:mlr7883 transcription regulator; TetR family transcriptional regulator complement(4758797..4759492) Actinosynnema mirum DSM 43827 8328240 YP_003101755.1 CDS Amir_4048 NC_013093.1 4759524 4762004 R PFAM: protein of unknown function DUF214; KEGG: afw:Anae109_1773 hypothetical protein; hypothetical protein complement(4759524..4762004) Actinosynnema mirum DSM 43827 8328241 YP_003101756.1 CDS Amir_4049 NC_013093.1 4762001 4762753 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0970 ABC transporter, ATPase subunit; ABC transporter complement(4762001..4762753) Actinosynnema mirum DSM 43827 8328242 YP_003101757.1 CDS Amir_4050 NC_013093.1 4762762 4763181 R hypothetical protein complement(4762762..4763181) Actinosynnema mirum DSM 43827 8328243 YP_003101758.1 CDS Amir_4051 NC_013093.1 4763398 4764075 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(4763398..4764075) Actinosynnema mirum DSM 43827 8328244 YP_003101759.1 CDS Amir_4052 NC_013093.1 4764199 4765356 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: mmr:Mmar10_2544 signal transduction histidine kinase; histidine kinase complement(4764199..4765356) Actinosynnema mirum DSM 43827 8328245 YP_003101760.1 CDS Amir_4053 NC_013093.1 4765573 4765962 D KEGG: afw:Anae109_4407 hypothetical protein; hypothetical protein 4765573..4765962 Actinosynnema mirum DSM 43827 8328246 YP_003101761.1 CDS Amir_4054 NC_013093.1 4765999 4766973 D PFAM: Helix-turn-helix type 11 domain protein; protein of unknown function UPF0074; KEGG: afw:Anae109_3752 helix-turn-helix type 11 domain-containing protein; Helix-turn-helix type 11 domain-containing protein 4765999..4766973 Actinosynnema mirum DSM 43827 8328247 YP_003101762.1 CDS Amir_4055 NC_013093.1 4767068 4767517 D KEGG: CG32198; hypothetical protein 4767068..4767517 Actinosynnema mirum DSM 43827 8328248 YP_003101763.1 CDS Amir_4056 NC_013093.1 4767474 4768103 R PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: bph:Bphy_6164 TetR family transcriptional regulator; TetR family transcriptional regulator complement(4767474..4768103) Actinosynnema mirum DSM 43827 8328249 YP_003101764.1 CDS Amir_4057 NC_013093.1 4768554 4769117 D PFAM: protein of unknown function DUF1486; KEGG: cak:Caul_1308 hypothetical protein; hypothetical protein 4768554..4769117 Actinosynnema mirum DSM 43827 8328250 YP_003101765.1 CDS Amir_4058 NC_013093.1 4769121 4769897 D PFAM: beta-lactamase domain protein; KEGG: bja:blr3078 hypothetical protein; beta-lactamase domain-containing protein 4769121..4769897 Actinosynnema mirum DSM 43827 8328251 YP_003101766.1 CDS Amir_4060 NC_013093.1 4772182 4772295 R hypothetical protein complement(4772182..4772295) Actinosynnema mirum DSM 43827 8328253 YP_003101767.1 CDS Amir_4061 NC_013093.1 4772447 4773184 R hypothetical protein complement(4772447..4773184) Actinosynnema mirum DSM 43827 8328254 YP_003101768.1 CDS Amir_4064 NC_013093.1 4775007 4775516 R PFAM: GCN5-related N-acetyltransferase; KEGG: bcn:Bcen_3699 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(4775007..4775516) Actinosynnema mirum DSM 43827 8328257 YP_003101769.1 CDS Amir_4065 NC_013093.1 4775744 4776331 R PFAM: regulatory protein TetR; KEGG: afw:Anae109_3254 TetR family transcriptional regulator; TetR family transcriptional regulator complement(4775744..4776331) Actinosynnema mirum DSM 43827 8328258 YP_003101770.1 CDS Amir_4068 NC_013093.1 4778416 4780200 R KEGG: lch:Lcho_2475 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; histidine kinase complement(4778416..4780200) Actinosynnema mirum DSM 43827 8328261 YP_003101771.1 CDS Amir_4069 NC_013093.1 4780190 4780888 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sus:Acid_5032 two component transcriptional regulator; winged helix family two component transcriptional regulator complement(4780190..4780888) Actinosynnema mirum DSM 43827 8328262 YP_003101772.1 CDS Amir_4070 NC_013093.1 4780947 4782023 D PFAM: peptidoglycan-binding domain 1 protein; KEGG: gur:Gura_3473 peptidoglycan binding domain- containing protein; peptidoglycan-binding domain 1 protein 4780947..4782023 Actinosynnema mirum DSM 43827 8328263 YP_003101773.1 CDS Amir_4071 NC_013093.1 4782020 4782778 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: vco:VC0395_A1173 ABC transporter, ATP-binding protein; ABC transporter 4782020..4782778 Actinosynnema mirum DSM 43827 8328264 YP_003101774.1 CDS Amir_4072 NC_013093.1 4782775 4784049 D PFAM: protein of unknown function DUF214; KEGG: gur:Gura_3474 ABC transporter; hypothetical protein 4782775..4784049 Actinosynnema mirum DSM 43827 8328265 YP_003101775.1 CDS Amir_4073 NC_013093.1 4784135 4784692 D hypothetical protein 4784135..4784692 Actinosynnema mirum DSM 43827 8328266 YP_003101776.1 CDS Amir_4074 NC_013093.1 4784689 4785243 D hypothetical protein 4784689..4785243 Actinosynnema mirum DSM 43827 8328267 YP_003101777.1 CDS Amir_4075 NC_013093.1 4785299 4786501 R TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: spe:Spro_3869 cysteine desulfurase family protein; cysteine desulfurase family protein complement(4785299..4786501) Actinosynnema mirum DSM 43827 8328268 YP_003101778.1 CDS Amir_4076 NC_013093.1 4786835 4788385 D PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: scl:sce3486 choline dehydrogenase; glucose-methanol-choline oxidoreductase 4786835..4788385 Actinosynnema mirum DSM 43827 8328269 YP_003101779.1 CDS Amir_4077 NC_013093.1 4788393 4789463 D PFAM: O-methyltransferase; methyltransferase type 12; methyltransferase type 11; KEGG: sfu:Sfum_0920 O-methyltransferase, family 2; O-methyltransferase 4788393..4789463 Actinosynnema mirum DSM 43827 8328270 YP_003101780.1 CDS Amir_4078 NC_013093.1 4789499 4790074 R TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: mxa:MXAN_3277 peroxidase, selenocysteine-containing; alkylhydroperoxidase like protein complement(4789499..4790074) Actinosynnema mirum DSM 43827 8328271 YP_003101781.1 CDS Amir_4079 NC_013093.1 4790204 4790653 R KEGG: cbg:CbuG_0320 hypothetical membrane spanning protein; hypothetical protein complement(4790204..4790653) Actinosynnema mirum DSM 43827 8328272 YP_003101782.1 CDS Amir_4080 NC_013093.1 4790664 4791674 R PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KR domain protein; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; KEGG: ade:Adeh_0777 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(4790664..4791674) Actinosynnema mirum DSM 43827 8328273 YP_003101783.1 CDS Amir_4081 NC_013093.1 4791735 4792226 R PFAM: flavin reductase domain protein FMN-binding; KEGG: pde:Pden_2689 flavin reductase domain protein, FMN-binding; flavin reductase domain-containing protein complement(4791735..4792226) Actinosynnema mirum DSM 43827 8328274 YP_003101784.1 CDS Amir_4082 NC_013093.1 4792223 4792681 R KEGG: pau:PA14_51770 hypothetical protein; hypothetical protein complement(4792223..4792681) Actinosynnema mirum DSM 43827 8328275 YP_003101785.1 CDS Amir_4083 NC_013093.1 4792683 4798487 R PFAM: beta-ketoacyl synthase; acyl transferase; KR domain protein; short-chain dehydrogenase/reductase SDR; KEGG: mca:MCA1238 polyketide synthase; erythronolide synthase complement(4792683..4798487) Actinosynnema mirum DSM 43827 8328276 YP_003101786.1 CDS Amir_4084 NC_013093.1 4798845 4800029 R PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: bur:Bcep18194_B1567 acyl-CoA dehydrogenase- like; acyl-CoA dehydrogenase type 2 domain-containing protein complement(4798845..4800029) Actinosynnema mirum DSM 43827 8328277 YP_003101787.1 CDS Amir_4085 NC_013093.1 4800084 4801268 R PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: bur:Bcep18194_B1567 acyl-CoA dehydrogenase- like; acyl-CoA dehydrogenase type 2 domain-containing protein complement(4800084..4801268) Actinosynnema mirum DSM 43827 8328278 YP_003101788.1 CDS Amir_4086 NC_013093.1 4801539 4802792 R PFAM: major facilitator superfamily MFS_1; KEGG: aha:AHA_1643 major facilitator transporter; major facilitator superfamily protein complement(4801539..4802792) Actinosynnema mirum DSM 43827 8328279 YP_003101789.1 CDS Amir_4087 NC_013093.1 4802988 4803509 D PFAM: helix-turn-helix HxlR type; KEGG: sme:SMc02225 hypothetical protein; HxlR family transcriptional regulator 4802988..4803509 Actinosynnema mirum DSM 43827 8328280 YP_003101790.1 CDS Amir_4088 NC_013093.1 4803494 4804423 R PFAM: alpha/beta hydrolase fold; KEGG: bja:blr8188 dehalogenase; alpha/beta hydrolase fold protein complement(4803494..4804423) Actinosynnema mirum DSM 43827 8328281 YP_003101791.1 CDS Amir_4089 NC_013093.1 4804602 4805828 R KEGG: mxa:MXAN_0277 hypothetical protein; hypothetical protein complement(4804602..4805828) Actinosynnema mirum DSM 43827 8328282 YP_003101792.1 CDS Amir_4090 NC_013093.1 4805992 4807317 R PFAM: glycosyl transferase family 2; KEGG: gbm:Gbem_1049 glycosyl transferase family 2; family 2 glycosyl transferase complement(4805992..4807317) Actinosynnema mirum DSM 43827 8328283 YP_003101793.1 CDS Amir_4091 NC_013093.1 4807459 4808637 R PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: bur:Bcep18194_B1567 acyl-CoA dehydrogenase- like; acyl-CoA dehydrogenase type 2 domain-containing protein complement(4807459..4808637) Actinosynnema mirum DSM 43827 8328284 YP_003101794.1 CDS Amir_4092 NC_013093.1 4808848 4810080 R PFAM: Epoxide hydrolase domain protein; alpha/beta hydrolase fold; KEGG: bja:bll7368 hydrolase; Epoxide hydrolase domain-containing protein complement(4808848..4810080) Actinosynnema mirum DSM 43827 8328285 YP_003101795.1 CDS Amir_4093 NC_013093.1 4810239 4811012 R PFAM: protein of unknown function DUF899 thioredoxin family protein; KEGG: pmy:Pmen_1335 protein of unknown function DUF899, thioredoxin family protein; hypothetical protein complement(4810239..4811012) Actinosynnema mirum DSM 43827 8328286 YP_003101796.1 CDS Amir_4094 NC_013093.1 4811063 4812199 R PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: bha:BH0710 hypothetical protein; oxidoreductase domain-containing protein complement(4811063..4812199) Actinosynnema mirum DSM 43827 8328287 YP_003101797.1 CDS Amir_4095 NC_013093.1 4812666 4813643 D KEGG: bpt:Bpet4347 hypothetical protein; hypothetical protein 4812666..4813643 Actinosynnema mirum DSM 43827 8328288 YP_003101798.1 CDS Amir_4096 NC_013093.1 4813644 4814522 R hypothetical protein complement(4813644..4814522) Actinosynnema mirum DSM 43827 8328289 YP_003101799.1 CDS Amir_4097 NC_013093.1 4814805 4816121 D PFAM: ABC-1 domain protein; KEGG: rsh:Rsph17029_0006 2-polyprenylphenol 6- hydroxylase; ABC transporter 4814805..4816121 Actinosynnema mirum DSM 43827 8328290 YP_003101800.1 CDS Amir_4098 NC_013093.1 4816129 4816764 D TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: gur:Gura_3352 uncharacterized peroxidase- related enzyme; peroxidase 4816129..4816764 Actinosynnema mirum DSM 43827 8328291 YP_003101801.1 CDS Amir_4099 NC_013093.1 4816761 4817639 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: msl:Msil_2581 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4816761..4817639 Actinosynnema mirum DSM 43827 8328292 YP_003101802.1 CDS Amir_4100 NC_013093.1 4817745 4819292 R PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: scl:sce3486 choline dehydrogenase; glucose-methanol-choline oxidoreductase complement(4817745..4819292) Actinosynnema mirum DSM 43827 8328293 YP_003101803.1 CDS Amir_4101 NC_013093.1 4819509 4820495 D PFAM: protein of unknown function DUF1702; hypothetical protein 4819509..4820495 Actinosynnema mirum DSM 43827 8328294 YP_003101804.1 CDS Amir_4102 NC_013093.1 4820492 4821850 D PFAM: cytochrome P450; KEGG: mxa:MXAN_2304 cytochrome P450 family protein; cytochrome P450 4820492..4821850 Actinosynnema mirum DSM 43827 8328295 YP_003101805.1 CDS Amir_4103 NC_013093.1 4821883 4822911 D KEGG: acp:A2cp1_3940 hypothetical protein; hypothetical protein 4821883..4822911 Actinosynnema mirum DSM 43827 8328296 YP_003101806.1 CDS Amir_4104 NC_013093.1 4823000 4823752 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bha:BH0851 AraC/XylS family transcriptional regulator; AraC family transcriptional regulator complement(4823000..4823752) Actinosynnema mirum DSM 43827 8328297 YP_003101807.1 CDS Amir_4105 NC_013093.1 4824164 4824862 D PFAM: regulatory protein TetR; KEGG: rfr:Rfer_0325 TetR family transcriptional regulator; TetR family transcriptional regulator 4824164..4824862 Actinosynnema mirum DSM 43827 8328298 YP_003101808.1 CDS Amir_4107 NC_013093.1 4825735 4826688 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: swi:Swit_1657 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein complement(4825735..4826688) Actinosynnema mirum DSM 43827 8328300 YP_003101809.1 CDS Amir_4108 NC_013093.1 4826774 4827343 D PFAM: regulatory protein TetR; KEGG: cak:Caul_4437 TetR family transcriptional regulator; TetR family transcriptional regulator 4826774..4827343 Actinosynnema mirum DSM 43827 8328301 YP_003101810.1 CDS Amir_4109 NC_013093.1 4827390 4827914 R PFAM: flavin reductase domain protein FMN-binding; KEGG: pde:Pden_2689 flavin reductase domain protein, FMN-binding; flavin reductase domain-containing protein complement(4827390..4827914) Actinosynnema mirum DSM 43827 8328302 YP_003101811.1 CDS Amir_4110 NC_013093.1 4827911 4829209 R PFAM: acyl transferase; KEGG: dsh:Dshi_1963 beta-ketoacyl synthase; acyl transferase complement(4827911..4829209) Actinosynnema mirum DSM 43827 8328303 YP_003101812.1 CDS Amir_4111 NC_013093.1 4829206 4830240 R KEGG: mxa:MXAN_7127 FG-GAP repeat protein; hypothetical protein complement(4829206..4830240) Actinosynnema mirum DSM 43827 8328304 YP_003101813.1 CDS Amir_4112 NC_013093.1 4830237 4832240 R PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; KEGG: mxa:MXAN_7127 FG-GAP repeat protein; ASPIC/UnbV domain-containing protein complement(4830237..4832240) Actinosynnema mirum DSM 43827 8328305 YP_003101814.1 CDS Amir_4113 NC_013093.1 4832516 4833262 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rpi:Rpic_1138 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(4832516..4833262) Actinosynnema mirum DSM 43827 8328306 YP_003101815.1 CDS Amir_4114 NC_013093.1 4833383 4834081 R PFAM: protein of unknown function DUF899 thioredoxin family protein; KEGG: pmy:Pmen_1335 protein of unknown function DUF899, thioredoxin family protein; hypothetical protein complement(4833383..4834081) Actinosynnema mirum DSM 43827 8328307 YP_003101816.1 CDS Amir_4115 NC_013093.1 4834113 4835666 R PFAM: AMP-dependent synthetase and ligase; KEGG: dsh:Dshi_0253 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase complement(4834113..4835666) Actinosynnema mirum DSM 43827 8328308 YP_003101817.1 CDS Amir_4116 NC_013093.1 4835663 4836493 R catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA; p-hydroxycinnamoyl CoA hydratase/lyase complement(4835663..4836493) Actinosynnema mirum DSM 43827 8328309 YP_003101818.1 CDS Amir_4117 NC_013093.1 4836901 4838868 D PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein; KEGG: mxa:MXAN_7127 FG-GAP repeat protein; ASPIC/UnbV domain-containing protein 4836901..4838868 Actinosynnema mirum DSM 43827 8328310 YP_003101819.1 CDS Amir_4118 NC_013093.1 4838906 4839967 D KEGG: mxa:MXAN_7127 FG-GAP repeat protein; hypothetical protein 4838906..4839967 Actinosynnema mirum DSM 43827 8328311 YP_003101820.1 CDS Amir_4119 NC_013093.1 4840147 4840935 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: bha:BH0851 AraC/XylS family transcriptional regulator; AraC family transcriptional regulator complement(4840147..4840935) Actinosynnema mirum DSM 43827 8328312 YP_003101821.1 CDS Amir_4120 NC_013093.1 4841924 4842496 D hypothetical protein 4841924..4842496 Actinosynnema mirum DSM 43827 8328313 YP_003101822.1 CDS Amir_4121 NC_013093.1 4842501 4844030 D KEGG: GK18511 gene product from transcript GK18511- RA; hypothetical protein 4842501..4844030 Actinosynnema mirum DSM 43827 8328314 YP_003101823.1 CDS Amir_4122 NC_013093.1 4844163 4845989 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: azc:AZC_2089 hypothetical protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4844163..4845989 Actinosynnema mirum DSM 43827 8328315 YP_003101824.1 CDS Amir_4123 NC_013093.1 4846114 4847415 D PFAM: PEP-utilizing protein; KEGG: ccs:CCNA_00571 phosphoenolpyruvate-protein phosphotransferase/phosphocarrier protein HPr/PTS system, glucose-specific IIA subunit; PEP-utilizing protein 4846114..4847415 Actinosynnema mirum DSM 43827 8328316 YP_003101825.1 CDS Amir_4124 NC_013093.1 4847422 4849437 R KEGG: ade:Adeh_3102 molybdopterin-binding xanthine dehydrogenase; isoquinoline 1-oxidoreductase complement(4847422..4849437) Actinosynnema mirum DSM 43827 8328317 YP_003101826.1 CDS Amir_4125 NC_013093.1 4849434 4849898 R PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: mxa:MXAN_1751 isoquinoline 1-oxidoreductase, alpha subunit; (2Fe-2S)-binding domain-containing protein complement(4849434..4849898) Actinosynnema mirum DSM 43827 8328318 YP_003101827.1 CDS Amir_4126 NC_013093.1 4850121 4850249 D hypothetical protein 4850121..4850249 Actinosynnema mirum DSM 43827 8328319 YP_003101828.1 CDS Amir_4127 NC_013093.1 4850429 4853086 R PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: scl:sce2990 hypothetical protein; SNF2-like protein complement(4850429..4853086) Actinosynnema mirum DSM 43827 8328320 YP_003101829.1 CDS Amir_4128 NC_013093.1 4853202 4856597 D PFAM: helicase domain protein; SNF2-related protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicase; KEGG: xau:Xaut_2988 helicase domain-containing protein; helicase domain-containing protein 4853202..4856597 Actinosynnema mirum DSM 43827 8328321 YP_003101830.1 CDS Amir_4129 NC_013093.1 4856688 4857368 R KEGG: hypothetical protein; hypothetical protein complement(4856688..4857368) Actinosynnema mirum DSM 43827 8328322 YP_003101831.1 CDS Amir_4130 NC_013093.1 4857632 4858666 R KEGG: scl:sce0662 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator complement(4857632..4858666) Actinosynnema mirum DSM 43827 8328323 YP_003101832.1 CDS Amir_4131 NC_013093.1 4858782 4860689 D KEGG: scl:sce0661 mannan endo-1,4-beta-mannosidase; mannan endo-1,4-beta-mannosidase 4858782..4860689 Actinosynnema mirum DSM 43827 8328324 YP_003101833.1 CDS Amir_4132 NC_013093.1 4860686 4861909 D PFAM: mandelate racemase/muconate lactonizing protein; KEGG: ccs:CCNA_02903 starvation sensing protein RspA; mandelate racemase/muconate lactonizing protein 4860686..4861909 Actinosynnema mirum DSM 43827 8328325 YP_003101834.1 CDS Amir_4133 NC_013093.1 4862064 4862561 D hypothetical protein 4862064..4862561 Actinosynnema mirum DSM 43827 8328326 YP_003101835.1 CDS Amir_4134 NC_013093.1 4862679 4864289 D PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: scl:sce2212 topoisomerase; cellulose-binding family protein 4862679..4864289 Actinosynnema mirum DSM 43827 8328327 YP_003101836.1 CDS Amir_4135 NC_013093.1 4864350 4865732 R PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: met:M446_1000 hypothetical protein; FAD-binding monooxygenase complement(4864350..4865732) Actinosynnema mirum DSM 43827 8328328 YP_003101837.1 CDS Amir_4136 NC_013093.1 4866204 4866674 R PFAM: calcium/calmodulin dependent protein kinase II association-domain protein; KEGG: pfl:PFL_3821 hypothetical protein; calcium/calmodulin dependent protein kinase II association-domain-containing protein complement(4866204..4866674) Actinosynnema mirum DSM 43827 8328329 YP_003101838.1 CDS Amir_4137 NC_013093.1 4866773 4868119 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: ppu:PP_4505 integral membrane sensor signal transduction histidine kinase; histidine kinase complement(4866773..4868119) Actinosynnema mirum DSM 43827 8328330 YP_003101839.1 CDS Amir_4138 NC_013093.1 4868119 4868856 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bte:BTH_II1765 DNA-binding response regulator; winged helix family two component transcriptional regulator complement(4868119..4868856) Actinosynnema mirum DSM 43827 8328331 YP_003101840.1 CDS Amir_4139 NC_013093.1 4869007 4870872 R KEGG: fibrocystin-L-like protein; hypothetical protein complement(4869007..4870872) Actinosynnema mirum DSM 43827 8328332 YP_003101841.1 CDS Amir_4140 NC_013093.1 4870916 4871779 R hypothetical protein complement(4870916..4871779) Actinosynnema mirum DSM 43827 8328333 YP_003101842.1 CDS Amir_4141 NC_013093.1 4872275 4874623 R PFAM: aminoglycoside phosphotransferase; KEGG: bps:BPSL0571 hypothetical protein; aminoglycoside phosphotransferase complement(4872275..4874623) Actinosynnema mirum DSM 43827 8328334 YP_003101843.1 CDS Amir_4142 NC_013093.1 4874586 4875404 R KEGG: dac:Daci_2301 hypothetical protein; hypothetical protein complement(4874586..4875404) Actinosynnema mirum DSM 43827 8328335 YP_003101844.1 CDS Amir_4143 NC_013093.1 4875413 4876252 R SMART: von Willebrand factor type A; KEGG: dac:Daci_2300 hypothetical protein; von Willebrand factor type A complement(4875413..4876252) Actinosynnema mirum DSM 43827 8328336 YP_003101845.1 CDS Amir_4144 NC_013093.1 4876453 4877442 D PFAM: pirin; KEGG: pap:PSPA7_4173 hypothetical protein; pirin 4876453..4877442 Actinosynnema mirum DSM 43827 8328337 YP_003101846.1 CDS Amir_4145 NC_013093.1 4877596 4879023 R KEGG: mxa:MXAN_0224 hypothetical protein; hypothetical protein complement(4877596..4879023) Actinosynnema mirum DSM 43827 8328338 YP_003101847.1 CDS Amir_4146 NC_013093.1 4879355 4879603 D hypothetical protein 4879355..4879603 Actinosynnema mirum DSM 43827 8328339 YP_003101848.1 CDS Amir_4147 NC_013093.1 4879564 4879800 D hypothetical protein 4879564..4879800 Actinosynnema mirum DSM 43827 8328340 YP_003101849.1 CDS Amir_4148 NC_013093.1 4879912 4880748 D PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sml:Smlt0507 arylesterase (aryl- ester hydrolase); alpha/beta hydrolase fold protein 4879912..4880748 Actinosynnema mirum DSM 43827 8328341 YP_003101850.1 CDS Amir_4149 NC_013093.1 4880803 4881765 R PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: dsh:Dshi_3592 Cna B domain-containing protein; Ricin B lectin complement(4880803..4881765) Actinosynnema mirum DSM 43827 8328342 YP_003101851.1 CDS Amir_4150 NC_013093.1 4882198 4883199 R PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: hypothetical protein; Ricin B lectin complement(4882198..4883199) Actinosynnema mirum DSM 43827 8328343 YP_003101852.1 CDS Amir_4151 NC_013093.1 4883864 4884826 R PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: hdu:HD0746 endo-1,4-beta-xylanase A; Ricin B lectin complement(4883864..4884826) Actinosynnema mirum DSM 43827 8328344 YP_003101853.1 CDS Amir_4152 NC_013093.1 4885000 4886349 R PFAM: cellulose-binding family II; glycoside hydrolase family 5; SMART: cellulose-binding family II; KEGG: sde:Sde_0064 secreted beta- mannosidase; cellulose-binding family protein complement(4885000..4886349) Actinosynnema mirum DSM 43827 8328345 YP_003101854.1 CDS Amir_4153 NC_013093.1 4886550 4888169 R KEGG: mno:Mnod_3288 hypothetical protein; hypothetical protein complement(4886550..4888169) Actinosynnema mirum DSM 43827 8328346 YP_003101855.1 CDS Amir_4154 NC_013093.1 4888507 4890438 D KEGG: pap:PSPA7_4431 hypothetical protein; hypothetical protein 4888507..4890438 Actinosynnema mirum DSM 43827 8328347 YP_003101856.1 CDS Amir_4155 NC_013093.1 4890557 4891486 D PFAM: lipolytic protein G-D-S-L family; KEGG: bvi:Bcep1808_2033 allergen V5/TPX-1 family protein; G-D-S-L family lipolytic protein 4890557..4891486 Actinosynnema mirum DSM 43827 8328348 YP_003101857.1 CDS Amir_4156 NC_013093.1 4891759 4892562 D KEGG: hypothetical LOC100006405; hypothetical protein 4891759..4892562 Actinosynnema mirum DSM 43827 8328349 YP_003101858.1 CDS Amir_4157 NC_013093.1 4892613 4893224 D KEGG: hypothetical protein; hypothetical protein 4892613..4893224 Actinosynnema mirum DSM 43827 8328350 YP_003101859.1 CDS Amir_4158 NC_013093.1 4893344 4893847 D this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4893344..4893847 Actinosynnema mirum DSM 43827 8328351 YP_003101860.1 CDS Amir_4159 NC_013093.1 4894193 4895020 R KEGG: rme:Rmet_4144 citrate synthase; citrate synthase complement(4894193..4895020) Actinosynnema mirum DSM 43827 8328352 YP_003101861.1 CDS Amir_4160 NC_013093.1 4895017 4896240 R PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rme:Rmet_4145 L-carnitine dehydratase/bile acid-inducible protein F; L-carnitine dehydratase/bile acid-inducible protein F complement(4895017..4896240) Actinosynnema mirum DSM 43827 8328353 YP_003101862.1 CDS Amir_4161 NC_013093.1 4896237 4897748 R PFAM: protein of unknown function DUF112 transmembrane; KEGG: bpt:Bpet0754 hypothetical protein; hypothetical protein complement(4896237..4897748) Actinosynnema mirum DSM 43827 8328354 YP_003101863.1 CDS Amir_4162 NC_013093.1 4897748 4898335 R KEGG: bja:blr3162 hypothetical protein; hypothetical protein complement(4897748..4898335) Actinosynnema mirum DSM 43827 8328355 YP_003101864.1 CDS Amir_4163 NC_013093.1 4898332 4899318 R PFAM: conserved hypothetical protein; KEGG: oan:Oant_3917 uncharacterized protein UPF0065; hypothetical protein complement(4898332..4899318) Actinosynnema mirum DSM 43827 8328356 YP_003101865.1 CDS Amir_4164 NC_013093.1 4899456 4900235 D PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: cti:RALTA_B1947 transcriptional regulator, IclR family; IclR family transcriptional regulator 4899456..4900235 Actinosynnema mirum DSM 43827 8328357 YP_003101866.1 CDS Amir_4165 NC_013093.1 4900292 4900882 D PFAM: Dimethylmenaquinone methyltransferase; KEGG: mrd:Mrad2831_3497 dimethylmenaquinone methyltransferase; Dimethylmenaquinone methyltransferase 4900292..4900882 Actinosynnema mirum DSM 43827 8328358 YP_003101867.1 CDS Amir_4166 NC_013093.1 4900890 4901810 D PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: ppf:Pput_1368 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 4900890..4901810 Actinosynnema mirum DSM 43827 8328359 YP_003101868.1 CDS Amir_4167 NC_013093.1 4902799 4903947 R KEGG: hypothetical protein; hypothetical protein complement(4902799..4903947) Actinosynnema mirum DSM 43827 8328360 YP_003101869.1 CDS Amir_4168 NC_013093.1 4904208 4905146 R PFAM: protein of unknown function DUF1177; KEGG: vei:Veis_1102 protein of unknown function DUF1177; hypothetical protein complement(4904208..4905146) Actinosynnema mirum DSM 43827 8328361 YP_003101870.1 CDS Amir_4169 NC_013093.1 4905242 4905883 R PFAM: Asp/Glu/hydantoin racemase; KEGG: jan:Jann_1486 Asp/Glu racemase; Asp/Glu/hydantoin racemase complement(4905242..4905883) Actinosynnema mirum DSM 43827 8328362 YP_003101871.1 CDS Amir_4170 NC_013093.1 4905880 4906599 R PFAM: AroM family protein; KEGG: spe:Spro_1025 hypothetical protein; AroM family protein complement(4905880..4906599) Actinosynnema mirum DSM 43827 8328363 YP_003101872.1 CDS Amir_4171 NC_013093.1 4906592 4908292 R PFAM: Oligopeptide transporter OPT superfamily protein; KEGG: vei:Veis_1103 oligopeptide transporter OPT superfamily protein; Oligopeptide transporter OPT superfamily protein complement(4906592..4908292) Actinosynnema mirum DSM 43827 8328364 YP_003101873.1 CDS Amir_4172 NC_013093.1 4908305 4909054 R PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: reu:Reut_B5545 regulatory protein, IclR; IclR family transcriptional regulator complement(4908305..4909054) Actinosynnema mirum DSM 43827 8328365 YP_003101874.1 CDS Amir_4173 NC_013093.1 4909181 4909930 D alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4909181..4909930 Actinosynnema mirum DSM 43827 8328366 YP_003101875.1 CDS Amir_4174 NC_013093.1 4910160 4911641 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; cellulose-binding family II; SMART: serine/threonine protein kinase; cellulose- binding family II; tyrosine protein kinase; KEGG: acp:A2cp1_2229 serine/threonine protein kinase with TPR repeats; serine/threonine protein kinase 4910160..4911641 Actinosynnema mirum DSM 43827 8328367 YP_003101876.1 CDS Amir_4175 NC_013093.1 4911853 4913475 D hypothetical protein 4911853..4913475 Actinosynnema mirum DSM 43827 8328368 YP_003101877.1 CDS Amir_4176 NC_013093.1 4913829 4915280 D hypothetical protein 4913829..4915280 Actinosynnema mirum DSM 43827 8328369 YP_003101878.1 CDS Amir_4177 NC_013093.1 4915343 4916635 R PFAM: pectate lyase; Ricin B lectin; SMART: Ricin B lectin; KEGG: hypothetical protein; pectate lyase complement(4915343..4916635) Actinosynnema mirum DSM 43827 8328370 YP_003101879.1 CDS Amir_4178 NC_013093.1 4916834 4917778 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: msl:Msil_0872 alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase GroES domain-containing protein complement(4916834..4917778) Actinosynnema mirum DSM 43827 8328371 YP_003101880.1 CDS Amir_4179 NC_013093.1 4917920 4918420 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: abo:ABO_0014 MarR family transcriptional regulator; MarR family transcriptional regulator 4917920..4918420 Actinosynnema mirum DSM 43827 8328372 YP_003101881.1 CDS Amir_4180 NC_013093.1 4918488 4919435 D PFAM: FAD dependent oxidoreductase; KEGG: similar to D-aspartate oxidase; K00272 D- aspartate oxidase; D-aspartate oxidase 4918488..4919435 Actinosynnema mirum DSM 43827 8328373 YP_003101882.1 CDS Amir_4181 NC_013093.1 4919670 4920449 D TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: afw:Anae109_1933 methionine aminopeptidase, type I; methionine aminopeptidase, type I 4919670..4920449 Actinosynnema mirum DSM 43827 8328374 YP_003101883.1 CDS Amir_4182 NC_013093.1 4920537 4922609 R SMART: ATPase AAA; hypothetical protein; KEGG: scl:sce5225 protein kinase; ATPase AAA complement(4920537..4922609) Actinosynnema mirum DSM 43827 8328375 YP_003101884.1 CDS Amir_4183 NC_013093.1 4922638 4924287 R PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: bcu:BCAH820_0093 DNA-binding protein; hypothetical protein complement(4922638..4924287) Actinosynnema mirum DSM 43827 8328376 YP_003101885.1 CDS Amir_4184 NC_013093.1 4924654 4926264 D PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 4924654..4926264 Actinosynnema mirum DSM 43827 8328377 YP_003101886.1 CDS Amir_4185 NC_013093.1 4926336 4927892 R TIGRFAM: apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: abo:ABO_1940 apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase complement(4926336..4927892) Actinosynnema mirum DSM 43827 8328378 YP_003101887.1 CDS Amir_4186 NC_013093.1 4927987 4929573 R KEGG: met:M446_3732 von Willebrand factor type A; hypothetical protein complement(4927987..4929573) Actinosynnema mirum DSM 43827 8328379 YP_003101888.1 CDS Amir_4187 NC_013093.1 4929747 4930685 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: oxidoreductase protein; short chain dehydrogenase complement(4929747..4930685) Actinosynnema mirum DSM 43827 8328380 YP_003101889.1 CDS Amir_4188 NC_013093.1 4930876 4931772 D SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; XRE family transcriptional regulator 4930876..4931772 Actinosynnema mirum DSM 43827 8328381 YP_003101890.1 CDS Amir_4189 NC_013093.1 4931836 4932681 R PFAM: alpha/beta hydrolase fold; KEGG: alpha/beta hydrolase protein; alpha/beta hydrolase fold protein complement(4931836..4932681) Actinosynnema mirum DSM 43827 8328382 YP_003101891.1 CDS Amir_4190 NC_013093.1 4932779 4933255 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: scl:sce8843 MarR family transcriptional regulator; MarR family transcriptional regulator 4932779..4933255 Actinosynnema mirum DSM 43827 8328383 YP_003101892.1 CDS Amir_4191 NC_013093.1 4933363 4934979 D PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 4933363..4934979 Actinosynnema mirum DSM 43827 8328384 YP_003101893.1 CDS Amir_4192 NC_013093.1 4935123 4935548 D PFAM: ferric-uptake regulator; KEGG: hhe:HH0942 transcriptional regulator; Fur family ferric uptake regulator 4935123..4935548 Actinosynnema mirum DSM 43827 8328385 YP_003101894.1 CDS Amir_4193 NC_013093.1 4935633 4937861 D TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: pol:Bpro_0678 catalase/peroxidase HPI; catalase/peroxidase HPI 4935633..4937861 Actinosynnema mirum DSM 43827 8328386 YP_003101895.1 CDS Amir_4194 NC_013093.1 4938033 4941230 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: she:Shewmr4_1596 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin complement(4938033..4941230) Actinosynnema mirum DSM 43827 8328387 YP_003101896.1 CDS Amir_4195 NC_013093.1 4941518 4944778 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: she:Shewmr4_1596 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin complement(4941518..4944778) Actinosynnema mirum DSM 43827 8328388 YP_003101897.1 CDS Amir_4196 NC_013093.1 4945227 4947227 R TIGRFAM: hypothetical protein; PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein complement(4945227..4947227) Actinosynnema mirum DSM 43827 8328389 YP_003101898.1 CDS Amir_4197 NC_013093.1 4947433 4947585 D hypothetical protein 4947433..4947585 Actinosynnema mirum DSM 43827 8328390 YP_003101899.1 CDS Amir_4198 NC_013093.1 4947727 4949190 D KEGG: xca:xccb100_0130 exported pectinesterase; PFAM: pectinesterase; Ricin B lectin; SMART: Ricin B lectin; pectinesterase 4947727..4949190 Actinosynnema mirum DSM 43827 8328391 YP_003101900.1 CDS Amir_4199 NC_013093.1 4949211 4950635 D PFAM: Ricin B lectin; pectate lyase/Amb allergen; SMART: Ricin B lectin; Parallel beta-helix repeat; pectate lyase/Amb allergen; KEGG: bha:BH0698 pectate lyase; Ricin B lectin 4949211..4950635 Actinosynnema mirum DSM 43827 8328392 YP_003101901.1 CDS Amir_4200 NC_013093.1 4950817 4951386 D hypothetical protein 4950817..4951386 Actinosynnema mirum DSM 43827 8328393 YP_003101902.1 CDS Amir_4201 NC_013093.1 4951417 4952217 R catalyzes the formation of precorrin 6x from precorrin 5; precorrin 6A synthase complement(4951417..4952217) Actinosynnema mirum DSM 43827 8328394 YP_003101903.1 CDS Amir_4202 NC_013093.1 4952264 4952878 R PFAM: regulatory protein TetR; KEGG: sus:Acid_4679 TetR family transcriptional regulator; TetR family transcriptional regulator complement(4952264..4952878) Actinosynnema mirum DSM 43827 8328395 YP_003101904.1 CDS Amir_4203 NC_013093.1 4952923 4954386 D PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: bsu:BSU10500 hypothetical protein; FAD-binding monooxygenase 4952923..4954386 Actinosynnema mirum DSM 43827 8328396 YP_003101905.1 CDS Amir_4204 NC_013093.1 4954489 4955736 R catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase complement(4954489..4955736) Actinosynnema mirum DSM 43827 8328397 YP_003101906.1 CDS Amir_4205 NC_013093.1 4955816 4956940 R KEGG: bmj:BMULJ_04091 APA family basic amino acid/polyamine antiporter; APA family basic amino acid/polyamine antiporter complement(4955816..4956940) Actinosynnema mirum DSM 43827 8328398 YP_003101907.1 CDS Amir_4206 NC_013093.1 4956937 4958292 R KEGG: rso:RSp1425 L-ornithine 5-monooxygenase oxidoreductase protein; L-ornithine 5-monooxygenase oxidoreductase protein complement(4956937..4958292) Actinosynnema mirum DSM 43827 8328399 YP_003101908.1 CDS Amir_4207 NC_013093.1 4958336 4959415 R PFAM: FAD dependent oxidoreductase; KEGG: bpy:Bphyt_0284 FAD dependent oxidoreductase; FAD dependent oxidoreductase complement(4958336..4959415) Actinosynnema mirum DSM 43827 8328400 YP_003101909.1 CDS Amir_4208 NC_013093.1 4959412 4961349 R PFAM: tRNA synthetase class I (M); cupin; KEGG: pen:PSEEN0982 methionine--tRNA ligase; methionine--tRNA ligase complement(4959412..4961349) Actinosynnema mirum DSM 43827 8328401 YP_003101910.1 CDS Amir_4209 NC_013093.1 4961555 4962097 R KEGG: hypothetical protein; hypothetical protein complement(4961555..4962097) Actinosynnema mirum DSM 43827 8328402 YP_003101911.1 CDS Amir_4210 NC_013093.1 4962201 4963190 R PFAM: protein of unknown function DUF6 transmembrane; KEGG: tmz:Tmz1t_1271 hypothetical protein; hypothetical protein complement(4962201..4963190) Actinosynnema mirum DSM 43827 8328403 YP_003101912.1 CDS Amir_4211 NC_013093.1 4963227 4964516 R PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: rso:RS03119 transmembrane protein; FAD-binding monooxygenase complement(4963227..4964516) Actinosynnema mirum DSM 43827 8328404 YP_003101913.1 CDS Amir_4212 NC_013093.1 4964563 4965288 R PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: rso:RS03114 hypothetical protein; rhodanese domain-containing protein complement(4964563..4965288) Actinosynnema mirum DSM 43827 8328405 YP_003101914.1 CDS Amir_4213 NC_013093.1 4965298 4966953 R PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS03108 hypothetical protein; AMP-dependent synthetase and ligase complement(4965298..4966953) Actinosynnema mirum DSM 43827 8328406 YP_003101915.1 CDS Amir_4214 NC_013093.1 4966937 4967851 R PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: rso:RS03113 esterase protein; alpha/beta hydrolase fold-3 domain-containing protein complement(4966937..4967851) Actinosynnema mirum DSM 43827 8328407 YP_003101916.1 CDS Amir_4215 NC_013093.1 4967856 4969499 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS03108 hypothetical protein; amino acid adenylation domain-containing protein complement(4967856..4969499) Actinosynnema mirum DSM 43827 8328408 YP_003101917.1 CDS Amir_4216 NC_013093.1 4969496 4969954 R PFAM: GCN5-related N-acetyltransferase; KEGG: rso:RS03106 acetyltransferase protein; GCN5-like N-acetyltransferase complement(4969496..4969954) Actinosynnema mirum DSM 43827 8328409 YP_003101918.1 CDS Amir_4217 NC_013093.1 4969966 4970487 R KEGG: rso:RS03105 hypothetical protein; hypothetical protein complement(4969966..4970487) Actinosynnema mirum DSM 43827 8328410 YP_003101919.1 CDS Amir_4218 NC_013093.1 4971419 4972321 D PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: aha:AHA_4117 regulatory protein, LysR:LysR, substrate-binding; LysR family transcriptional regulator 4971419..4972321 Actinosynnema mirum DSM 43827 8328411 YP_003101920.1 CDS Amir_4219 NC_013093.1 4972422 4973201 D PFAM: inositol monophosphatase; KEGG: rru:Rru_A1076 inositol monophosphatase; inositol monophosphatase 4972422..4973201 Actinosynnema mirum DSM 43827 8328412 YP_003101921.1 CDS Amir_4220 NC_013093.1 4973198 4973830 D PFAM: NAD-dependent epimerase/dehydratase; KEGG: dsh:Dshi_0026 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4973198..4973830 Actinosynnema mirum DSM 43827 8328413 YP_003101922.1 CDS Amir_4221 NC_013093.1 4974321 4974875 D KEGG: hypothetical protein; hypothetical protein 4974321..4974875 Actinosynnema mirum DSM 43827 8328414 YP_003101923.1 CDS Amir_4222 NC_013093.1 4974882 4975214 D hypothetical protein 4974882..4975214 Actinosynnema mirum DSM 43827 8328415 YP_003101924.1 CDS Amir_4223 NC_013093.1 4975211 4976107 D KEGG: GK21128 gene product from transcript GK21128- RA; hypothetical protein 4975211..4976107 Actinosynnema mirum DSM 43827 8328416 YP_003101925.1 CDS Amir_4224 NC_013093.1 4976219 4976980 R hypothetical protein complement(4976219..4976980) Actinosynnema mirum DSM 43827 8328417 YP_003101926.1 CDS Amir_4225 NC_013093.1 4977378 4979276 D PFAM: glycoside hydrolase family 5; KEGG: hypothetical protein; glycoside hydrolase family protein 4977378..4979276 Actinosynnema mirum DSM 43827 8328418 YP_003101927.1 CDS Amir_4226 NC_013093.1 4979319 4980107 D KEGG: hypothetical protein; hypothetical protein 4979319..4980107 Actinosynnema mirum DSM 43827 8328419 YP_003101928.1 CDS Amir_4227 NC_013093.1 4980190 4980525 D PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bcz:pE33L466_0439 transcriptional regulator; ArsR family transcriptional regulator 4980190..4980525 Actinosynnema mirum DSM 43827 8328420 YP_003101929.1 CDS Amir_4228 NC_013093.1 4980522 4982132 D PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; KEGG: net:Neut_0352 sulphate transporter; sulfate transporter 4980522..4982132 Actinosynnema mirum DSM 43827 8328421 YP_003101930.1 CDS Amir_4229 NC_013093.1 4982163 4982939 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: atc:AGR_pAT_269 hypothetical protein; MerR family transcriptional regulator complement(4982163..4982939) Actinosynnema mirum DSM 43827 8328422 YP_003101931.1 CDS Amir_4230 NC_013093.1 4983064 4983708 D hypothetical protein 4983064..4983708 Actinosynnema mirum DSM 43827 8328423 YP_003101932.1 CDS Amir_4231 NC_013093.1 4983795 4984361 R PFAM: regulatory protein TetR; KEGG: bcm:Bcenmc03_5854 hypothetical protein; TetR family transcriptional regulator complement(4983795..4984361) Actinosynnema mirum DSM 43827 8328424 YP_003101933.1 CDS Amir_4232 NC_013093.1 4984434 4984913 D hypothetical protein 4984434..4984913 Actinosynnema mirum DSM 43827 8328425 YP_003101934.1 CDS Amir_4233 NC_013093.1 4984945 4985376 D PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 4984945..4985376 Actinosynnema mirum DSM 43827 8328426 YP_003101935.1 CDS Amir_4234 NC_013093.1 4985692 4986588 D TIGRFAM: methyltransferase; PFAM: O-methyltransferase; KEGG: bur:Bcep18194_B1573 protein of unknown function Mtu_121; methyltransferase 4985692..4986588 Actinosynnema mirum DSM 43827 8328427 YP_003101936.1 CDS Amir_4235 NC_013093.1 4986728 4987930 D PFAM: cytochrome P450; KEGG: bca:BCE_2696 cytochrome P450; cytochrome P450 4986728..4987930 Actinosynnema mirum DSM 43827 8328428 YP_003101937.1 CDS Amir_4236 NC_013093.1 4988138 4989745 D KEGG: sus:Acid_0740 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; RecQ family ATP-dependent DNA helicase 4988138..4989745 Actinosynnema mirum DSM 43827 8328429 YP_003101938.1 CDS Amir_4237 NC_013093.1 4989937 4990638 D PFAM: glycoside hydrolase family 11; KEGG: sde:Sde_3061 xylanase/chitin deacetylase-like; endo-1,4-beta-xylanase 4989937..4990638 Actinosynnema mirum DSM 43827 8328430 YP_003101939.1 CDS Amir_4238 NC_013093.1 4990794 4996277 R PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; carboxyl transferase; biotin/lipoyl attachment domain- containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: aba:Acid345_0466 carbamoyl-phosphate synthase L chain, ATP-binding; carbamoyl-phosphate synthase L chain ATP- binding complement(4990794..4996277) Actinosynnema mirum DSM 43827 8328431 YP_003101940.1 CDS Amir_4239 NC_013093.1 4996684 4997490 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_2483 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein complement(4996684..4997490) Actinosynnema mirum DSM 43827 8328432 YP_003101941.1 CDS Amir_4240 NC_013093.1 4997487 4998392 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: xfm:Xfasm12_1606 ABC transporter sugar permease; ABC transporter inner membrane protein complement(4997487..4998392) Actinosynnema mirum DSM 43827 8328433 YP_003101942.1 CDS Amir_4241 NC_013093.1 4998389 4999657 R PFAM: extracellular solute-binding protein family 1; KEGG: sit:TM1040_3216 extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(4998389..4999657) Actinosynnema mirum DSM 43827 8328434 YP_003101943.1 CDS Amir_4242 NC_013093.1 5000032 5000559 D hypothetical protein 5000032..5000559 Actinosynnema mirum DSM 43827 8328435 YP_003101944.1 CDS Amir_4243 NC_013093.1 5000650 5001642 R PFAM: aldo/keto reductase; KEGG: cak:Caul_4616 aldo/keto reductase; aldo/keto reductase complement(5000650..5001642) Actinosynnema mirum DSM 43827 8328436 YP_003101945.1 CDS Amir_4244 NC_013093.1 5001773 5002636 D SMART: helix-turn-helix domain protein; KEGG: rle:RL4049 hypothetical protein; helix-turn-helix domain-containing protein 5001773..5002636 Actinosynnema mirum DSM 43827 8328437 YP_003101946.1 CDS Amir_4245 NC_013093.1 5002809 5003219 D KEGG: sml:Smlt3526 outer membrane lipoprotein; hypothetical protein 5002809..5003219 Actinosynnema mirum DSM 43827 8328438 YP_003101947.1 CDS Amir_4246 NC_013093.1 5003295 5004182 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aav:Aave_0303 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(5003295..5004182) Actinosynnema mirum DSM 43827 8328439 YP_003101948.1 CDS Amir_4247 NC_013093.1 5004188 5005015 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: rpb:RPB_0526 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(5004188..5005015) Actinosynnema mirum DSM 43827 8328440 YP_003101949.1 CDS Amir_4248 NC_013093.1 5005205 5006023 D hypothetical protein 5005205..5006023 Actinosynnema mirum DSM 43827 8328441 YP_003101950.1 CDS Amir_4249 NC_013093.1 5006027 5007454 D hypothetical protein 5006027..5007454 Actinosynnema mirum DSM 43827 8328442 YP_003101951.1 CDS Amir_4250 NC_013093.1 5007451 5009280 D KEGG: bvi:Bcep1808_7108 ATPase; hypothetical protein 5007451..5009280 Actinosynnema mirum DSM 43827 8328443 YP_003101952.1 CDS Amir_4251 NC_013093.1 5009351 5010694 R KEGG: mxa:MXAN_1171 oxidoreductase, short chain dehydrogenase/reductase family; oxidoreductase, short chain dehydrogenase/reductase family complement(5009351..5010694) Actinosynnema mirum DSM 43827 8328444 YP_003101953.1 CDS Amir_4252 NC_013093.1 5011299 5011709 R KEGG: sme:SMa0312 hypothetical protein; hypothetical protein complement(5011299..5011709) Actinosynnema mirum DSM 43827 8328449 YP_003101954.1 CDS Amir_4253 NC_013093.1 5011825 5012421 D KEGG: scl:sce1386 galactoside O-acetyltransferase; galactoside O-acetyltransferase 5011825..5012421 Actinosynnema mirum DSM 43827 8328450 YP_003101955.1 CDS Amir_4254 NC_013093.1 5012444 5012707 R hypothetical protein complement(5012444..5012707) Actinosynnema mirum DSM 43827 8328451 YP_003101956.1 CDS Amir_4255 NC_013093.1 5012927 5014051 D KEGG: excinuclease ABC C subunit domain protein; hypothetical protein 5012927..5014051 Actinosynnema mirum DSM 43827 8328452 YP_003101957.1 CDS Amir_4256 NC_013093.1 5014057 5015076 R KEGG: rce:RC1_0609 D-alanine--D-alanine ligase B; D-alanine--D-alanine ligase complement(5014057..5015076) Actinosynnema mirum DSM 43827 8328453 YP_003101958.1 CDS Amir_4257 NC_013093.1 5015080 5016369 R KEGG: predicted protein; hypothetical protein complement(5015080..5016369) Actinosynnema mirum DSM 43827 8328454 YP_003101959.1 CDS Amir_4258 NC_013093.1 5016432 5017286 R PFAM: O-methyltransferase; KEGG: zgc:113054; O-methyltransferase complement(5016432..5017286) Actinosynnema mirum DSM 43827 8328455 YP_003101960.1 CDS Amir_4259 NC_013093.1 5017283 5018503 R PFAM: 3-dehydroquinate synthase; KEGG: hypothetical protein; K01735 3- dehydroquinate synthase; 3-dehydroquinate synthase complement(5017283..5018503) Actinosynnema mirum DSM 43827 8328456 YP_003101961.1 CDS Amir_4260 NC_013093.1 5018912 5019565 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(5018912..5019565) Actinosynnema mirum DSM 43827 8328457 YP_003101962.1 CDS Amir_4261 NC_013093.1 5019589 5020878 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(5019589..5020878) Actinosynnema mirum DSM 43827 8328458 YP_003101963.1 CDS Amir_4262 NC_013093.1 5020949 5023036 R PFAM: beta-lactamase; KEGG: swi:Swit_4612 beta-lactamase; beta-lactamase complement(5020949..5023036) Actinosynnema mirum DSM 43827 8328459 YP_003101964.1 CDS Amir_4263 NC_013093.1 5023373 5023705 R hypothetical protein complement(5023373..5023705) Actinosynnema mirum DSM 43827 8328460 YP_003101965.1 CDS Amir_4264 NC_013093.1 5023702 5023800 R hypothetical protein complement(5023702..5023800) Actinosynnema mirum DSM 43827 8328461 YP_003101966.1 CDS Amir_4265 NC_013093.1 5024123 5027659 R KEGG: bur:Bcep18194_B1559 hypothetical protein; hypothetical protein complement(5024123..5027659) Actinosynnema mirum DSM 43827 8328462 YP_003101967.1 CDS Amir_4266 NC_013093.1 5027774 5030689 R KEGG: bur:Bcep18194_B1559 hypothetical protein; hypothetical protein complement(5027774..5030689) Actinosynnema mirum DSM 43827 8328463 YP_003101968.1 CDS Amir_4267 NC_013093.1 5030801 5031103 D hypothetical protein 5030801..5031103 Actinosynnema mirum DSM 43827 8328464 YP_003101969.1 CDS Amir_4268 NC_013093.1 5031123 5031530 R PFAM: endoribonuclease L-PSP; KEGG: scl:sce5646 hypothetical protein; endoribonuclease L-PSP complement(5031123..5031530) Actinosynnema mirum DSM 43827 8328465 YP_003101970.1 CDS Amir_4269 NC_013093.1 5031607 5032377 D PFAM: protein of unknown function DUF124; KEGG: protein of unknown function DUF124; hypothetical protein 5031607..5032377 Actinosynnema mirum DSM 43827 8328466 YP_003101971.1 CDS Amir_4271 NC_013093.1 5033153 5033401 D hypothetical protein 5033153..5033401 Actinosynnema mirum DSM 43827 8328468 YP_003101972.1 CDS Amir_4272 NC_013093.1 5033537 5034286 R PFAM: alpha/beta hydrolase fold; KEGG: swi:Swit_1445 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein complement(5033537..5034286) Actinosynnema mirum DSM 43827 8328469 YP_003101973.1 CDS Amir_4273 NC_013093.1 5034388 5034825 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rpb:RPB_1659 MarR family transcriptional regulator; MarR family transcriptional regulator 5034388..5034825 Actinosynnema mirum DSM 43827 8328470 YP_003101974.1 CDS Amir_4274 NC_013093.1 5034949 5035632 D KEGG: aba:Acid345_2268 hypothetical protein; hypothetical protein 5034949..5035632 Actinosynnema mirum DSM 43827 8328471 YP_003101975.1 CDS Amir_4275 NC_013093.1 5035654 5038338 R PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: afw:Anae109_3347 transcriptional activator domain-containing protein; LuxR family transcriptional regulator complement(5035654..5038338) Actinosynnema mirum DSM 43827 8328472 YP_003101976.1 CDS Amir_4276 NC_013093.1 5038430 5038561 R hypothetical protein complement(5038430..5038561) Actinosynnema mirum DSM 43827 8328473 YP_003101977.1 CDS Amir_4277 NC_013093.1 5038992 5040149 R PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pfl:PFL_0942 Oye family NADH-dependent flavin oxidoreductase; NADH:flavin oxidoreductase/NADH oxidase complement(5038992..5040149) Actinosynnema mirum DSM 43827 8328474 YP_003101978.1 CDS Amir_4278 NC_013093.1 5040280 5040879 D PFAM: regulatory protein TetR; KEGG: bbt:BBta_0873 TetR family transcriptional regulator; TetR family transcriptional regulator 5040280..5040879 Actinosynnema mirum DSM 43827 8328475 YP_003101979.1 CDS Amir_4279 NC_013093.1 5040990 5041976 D PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce5395 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 5040990..5041976 Actinosynnema mirum DSM 43827 8328476 YP_003101980.1 CDS Amir_4280 NC_013093.1 5041976 5043313 D TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: scl:sce5396 hypothetical protein; MATE efflux family protein 5041976..5043313 Actinosynnema mirum DSM 43827 8328477 YP_003101981.1 CDS Amir_4281 NC_013093.1 5043300 5044298 R KEGG: spe:Spro_1475 hydrolase family protein; hydrolase family protein complement(5043300..5044298) Actinosynnema mirum DSM 43827 8328478 YP_003101982.1 CDS Amir_4282 NC_013093.1 5044329 5045093 D KEGG: bha:BH0194 repressor in the phenylacetic acid catabolic pathway; PaaX family transcriptional regulator 5044329..5045093 Actinosynnema mirum DSM 43827 8328479 YP_003101983.1 CDS Amir_4283 NC_013093.1 5045098 5045472 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bsu:BSU19120 hypothetical protein; ArsR family transcriptional regulator complement(5045098..5045472) Actinosynnema mirum DSM 43827 8328480 YP_003101984.1 CDS Amir_4284 NC_013093.1 5045568 5047532 D TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: afe:Lferr_0209 heavy metal translocating P- type ATPase; heavy metal translocating P-type ATPase 5045568..5047532 Actinosynnema mirum DSM 43827 8328481 YP_003101985.1 CDS Amir_4285 NC_013093.1 5047658 5048992 D PFAM: major facilitator superfamily MFS_1; KEGG: smd:Smed_5611 major facilitator superfamily MFS_1; major facilitator superfamily protein 5047658..5048992 Actinosynnema mirum DSM 43827 8328482 YP_003101986.1 CDS Amir_4286 NC_013093.1 5049053 5049409 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: dvm:DvMF_1207 transcriptional regulator, ArsR family; ArsR family transcriptional regulator complement(5049053..5049409) Actinosynnema mirum DSM 43827 8328483 YP_003101987.1 CDS Amir_4287 NC_013093.1 5049602 5050474 D PFAM: iron permease FTR1; KEGG: pde:Pden_1733 iron permease FTR1; iron permease FTR1 5049602..5050474 Actinosynnema mirum DSM 43827 8328484 YP_003101988.1 CDS Amir_4288 NC_013093.1 5050471 5051592 D KEGG: nmn:NMCC_0036 hypothetical protein; hypothetical protein 5050471..5051592 Actinosynnema mirum DSM 43827 8328485 YP_003101989.1 CDS Amir_4289 NC_013093.1 5051589 5052914 D TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: bur:Bcep18194_A3951 Dyp-type peroxidase; Dyp-type peroxidase family 5051589..5052914 Actinosynnema mirum DSM 43827 8328486 YP_003101990.1 CDS Amir_4290 NC_013093.1 5053009 5053407 D PFAM: Penicillinase repressor; KEGG: mxa:MXAN_7319 transcriptional regulator; CopY family transcriptional regulator 5053009..5053407 Actinosynnema mirum DSM 43827 8328487 YP_003101991.1 CDS Amir_4291 NC_013093.1 5053448 5053948 R PFAM: protein of unknown function DUF1470; KEGG: bbr:BB0827 hypothetical protein; hypothetical protein complement(5053448..5053948) Actinosynnema mirum DSM 43827 8328488 YP_003101992.1 CDS Amir_4292 NC_013093.1 5054017 5055105 D PFAM: Epoxide hydrolase domain protein; alpha/beta hydrolase fold; KEGG: bpy:Bphyt_5343 epoxide hydrolase domain protein; Epoxide hydrolase domain-containing protein 5054017..5055105 Actinosynnema mirum DSM 43827 8328489 YP_003101993.1 CDS Amir_4293 NC_013093.1 5055248 5056090 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pde:Pden_3525 ABC transporter; ABC transporter complement(5055248..5056090) Actinosynnema mirum DSM 43827 8328490 YP_003101994.1 CDS Amir_4294 NC_013093.1 5056087 5057181 R PFAM: transport system permease protein; KEGG: oan:Oant_2825 transport system permease protein; transport system permease complement(5056087..5057181) Actinosynnema mirum DSM 43827 8328491 YP_003101995.1 CDS Amir_4295 NC_013093.1 5057178 5058221 R PFAM: transport system permease protein; KEGG: oan:Oant_2826 transport system permease protein; transport system permease complement(5057178..5058221) Actinosynnema mirum DSM 43827 8328492 YP_003101996.1 CDS Amir_4296 NC_013093.1 5058218 5059258 R PFAM: periplasmic binding protein; KEGG: pde:Pden_3522 periplasmic binding protein; periplasmic binding protein complement(5058218..5059258) Actinosynnema mirum DSM 43827 8328493 YP_003101997.1 CDS Amir_4297 NC_013093.1 5059695 5060801 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap complement(5059695..5060801) Actinosynnema mirum DSM 43827 8328494 YP_003101998.1 CDS Amir_4298 NC_013093.1 5061303 5062049 R KEGG: PT repeat family protein; hypothetical protein complement(5061303..5062049) Actinosynnema mirum DSM 43827 8328495 YP_003101999.1 CDS Amir_4299 NC_013093.1 5062194 5062943 R PFAM: ANTAR domain protein; KEGG: afw:Anae109_3912 multi-sensor signal transduction histidine kinase; ANTAR domain-containing protein with unknown sensor complement(5062194..5062943) Actinosynnema mirum DSM 43827 8328496 YP_003102000.1 CDS Amir_4300 NC_013093.1 5063119 5063847 R PFAM: Orn/Lys/Arg decarboxylase domain protein; Orn/Lys/Arg decarboxylase major region; KEGG: bha:BH2640 lysine decarboxylase; Orn/Lys/Arg decarboxylase domain-containing protein complement(5063119..5063847) Actinosynnema mirum DSM 43827 8328497 YP_003102001.1 CDS Amir_4301 NC_013093.1 5063942 5064727 R PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: azo:azo0656 LuxR family transcriptional regulator; LuxR family transcriptional regulator complement(5063942..5064727) Actinosynnema mirum DSM 43827 8328498 YP_003102002.1 CDS Amir_4302 NC_013093.1 5065271 5066116 R PFAM: protein of unknown function DUF88; KEGG: dal:Dalk_1950 cold-shock DNA-binding domain protein; hypothetical protein complement(5065271..5066116) Actinosynnema mirum DSM 43827 8328499 YP_003102003.1 CDS Amir_4303 NC_013093.1 5066410 5067138 R KEGG: nmu:Nmul_A2202 hypothetical protein; hypothetical protein complement(5066410..5067138) Actinosynnema mirum DSM 43827 8328500 YP_003102004.1 CDS Amir_4305 NC_013093.1 5067812 5068663 D hypothetical protein 5067812..5068663 Actinosynnema mirum DSM 43827 8328502 YP_003102005.1 CDS Amir_4306 NC_013093.1 5068751 5069569 D PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: scl:sce6912 thiosulfate sulfurtransferase; rhodanese domain-containing protein 5068751..5069569 Actinosynnema mirum DSM 43827 8328503 YP_003102006.1 CDS Amir_4307 NC_013093.1 5069566 5070909 D PFAM: FAD linked oxidase domain protein; KEGG: scl:sce0752 glycolate oxidase; FAD linked oxidase domain-containing protein 5069566..5070909 Actinosynnema mirum DSM 43827 8328504 YP_003102007.1 CDS Amir_4308 NC_013093.1 5070938 5071699 D KEGG: reh:H16_A2809 peptidase, S33 family; hypothetical protein 5070938..5071699 Actinosynnema mirum DSM 43827 8328505 YP_003102008.1 CDS Amir_4309 NC_013093.1 5071806 5074973 D KEGG: mrd:Mrad2831_1394 hypothetical protein; hypothetical protein 5071806..5074973 Actinosynnema mirum DSM 43827 8328506 YP_003102009.1 CDS Amir_4310 NC_013093.1 5075204 5075815 R PFAM: flavin reductase domain protein FMN-binding; KEGG: flavoprotein oxidoreductase protein; flavin reductase domain-containing protein complement(5075204..5075815) Actinosynnema mirum DSM 43827 8328507 YP_003102010.1 CDS Amir_4311 NC_013093.1 5076012 5076908 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rpi:Rpic_3636 transcriptional regulator, LysR family; LysR family transcriptional regulator 5076012..5076908 Actinosynnema mirum DSM 43827 8328508 YP_003102011.1 CDS Amir_4312 NC_013093.1 5077001 5078215 D PFAM: luciferase-like monooxygenase; KEGG: ssuD; alkanesulfonate monooxygenase protein; Alkanesulfonate monooxygenase 5077001..5078215 Actinosynnema mirum DSM 43827 8328509 YP_003102012.1 CDS Amir_4313 NC_013093.1 5078230 5079423 D PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: bja:bll6452 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase type 2 domain-containing protein 5078230..5079423 Actinosynnema mirum DSM 43827 8328510 YP_003102013.1 CDS Amir_4314 NC_013093.1 5079547 5079645 D hypothetical protein 5079547..5079645 Actinosynnema mirum DSM 43827 8328511 YP_003102014.1 CDS Amir_4315 NC_013093.1 5079706 5080404 R PFAM: ThiJ/PfpI domain protein; KEGG: scl:sce8831 ThiJ/PfpI family protein; ThiJ/PfpI domain-containing protein complement(5079706..5080404) Actinosynnema mirum DSM 43827 8328512 YP_003102015.1 CDS Amir_4316 NC_013093.1 5080501 5081463 D PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6302 AraC family transcriptional regulator; AraC family transcriptional regulator 5080501..5081463 Actinosynnema mirum DSM 43827 8328513 YP_003102016.1 CDS Amir_4317 NC_013093.1 5081610 5082605 D PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_A3489 transcriptional regulator, AraC- family; AraC family transcriptional regulator 5081610..5082605 Actinosynnema mirum DSM 43827 8328514 YP_003102017.1 CDS Amir_4318 NC_013093.1 5082678 5082968 R hypothetical protein complement(5082678..5082968) Actinosynnema mirum DSM 43827 8328515 YP_003102018.1 CDS Amir_4320 NC_013093.1 5085486 5087150 D PFAM: extracellular solute-binding protein family 5; KEGG: bbt:BBta_4832 ABC transporter (substrate binding protein); family 5 extracellular solute-binding protein 5085486..5087150 Actinosynnema mirum DSM 43827 8328517 YP_003102019.1 CDS Amir_4321 NC_013093.1 5087147 5088118 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_4833 ABC transporter (permease protein); ABC transporter inner membrane protein 5087147..5088118 Actinosynnema mirum DSM 43827 8328518 YP_003102020.1 CDS Amir_4322 NC_013093.1 5088115 5088957 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_4834 ABC transporter (permease protein); ABC transporter inner membrane protein 5088115..5088957 Actinosynnema mirum DSM 43827 8328519 YP_003102021.1 CDS Amir_4323 NC_013093.1 5088936 5090579 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: peptide ABC transporter; ABC transporter 5088936..5090579 Actinosynnema mirum DSM 43827 8328520 YP_003102022.1 CDS Amir_4324 NC_013093.1 5090720 5092030 D TIGRFAM: hypothetical protein; PFAM: Cna B domain protein; KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein 5090720..5092030 Actinosynnema mirum DSM 43827 8328521 YP_003102023.1 CDS Amir_4325 NC_013093.1 5092080 5092490 R hypothetical protein complement(5092080..5092490) Actinosynnema mirum DSM 43827 8328522 YP_003102024.1 CDS Amir_4326 NC_013093.1 5092777 5093160 R KEGG: hypothetical protein; hypothetical protein complement(5092777..5093160) Actinosynnema mirum DSM 43827 8328523 YP_003102025.1 CDS Amir_4327 NC_013093.1 5093325 5093834 R hypothetical protein complement(5093325..5093834) Actinosynnema mirum DSM 43827 8328524 YP_003102026.1 CDS Amir_4328 NC_013093.1 5094141 5094656 R KEGG: scl:sce0948 hypothetical protein; hypothetical protein complement(5094141..5094656) Actinosynnema mirum DSM 43827 8328525 YP_003102027.1 CDS Amir_4329 NC_013093.1 5094764 5095636 D SMART: helix-turn-helix domain protein; KEGG: bra:BRADO4150 hypothetical protein; XRE family transcriptional regulator 5094764..5095636 Actinosynnema mirum DSM 43827 8328526 YP_003102028.1 CDS Amir_4330 NC_013093.1 5095709 5096992 D KEGG: scl:sce8953 hypothetical protein; hypothetical protein 5095709..5096992 Actinosynnema mirum DSM 43827 8328527 YP_003102029.1 CDS Amir_4331 NC_013093.1 5097047 5098291 R PFAM: glycoside hydrolase family 46; Ricin B lectin; SMART: Ricin B lectin; KEGG: bsu:BSU26890 chitosanase; glycoside hydrolase family protein complement(5097047..5098291) Actinosynnema mirum DSM 43827 8328528 YP_003102030.1 CDS Amir_4332 NC_013093.1 5098585 5099019 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dvm:DvMF_2540 response regulator receiver protein; response regulator receiver protein 5098585..5099019 Actinosynnema mirum DSM 43827 8328529 YP_003102031.1 CDS Amir_4333 NC_013093.1 5099183 5100976 D PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: oxidoreductase protein; K07077; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 5099183..5100976 Actinosynnema mirum DSM 43827 8328530 YP_003102032.1 CDS Amir_4335 NC_013093.1 5102067 5102588 R PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: aha:AHA_0491 AsnC family transcriptional regulator; AsnC family transcriptional regulator complement(5102067..5102588) Actinosynnema mirum DSM 43827 8328532 YP_003102033.1 CDS Amir_4336 NC_013093.1 5102644 5102913 R hypothetical protein complement(5102644..5102913) Actinosynnema mirum DSM 43827 8328533 YP_003102034.1 CDS Amir_4337 NC_013093.1 5103039 5103926 R PFAM: integral membrane protein TerC; KEGG: integral membrane protein TerC; integral membrane protein TerC complement(5103039..5103926) Actinosynnema mirum DSM 43827 8328534 YP_003102035.1 CDS Amir_4338 NC_013093.1 5104555 5105250 R PFAM: regulatory protein TetR; KEGG: nha:Nham_3206 TetR family transcriptional regulator; TetR family transcriptional regulator complement(5104555..5105250) Actinosynnema mirum DSM 43827 8328535 YP_003102036.1 CDS Amir_4339 NC_013093.1 5105234 5106538 R PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: sme:SMc02891 oxidoreductase transmembrane protein; FAD-binding monooxygenase complement(5105234..5106538) Actinosynnema mirum DSM 43827 8328536 YP_003102037.1 CDS Amir_4340 NC_013093.1 5106593 5107792 R PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_3850 major facilitator transporter; major facilitator superfamily protein complement(5106593..5107792) Actinosynnema mirum DSM 43827 8328537 YP_003102038.1 CDS Amir_4341 NC_013093.1 5107865 5108902 R KEGG: met:M446_2055 methyl-accepting chemotaxis sensory transducer; hypothetical protein complement(5107865..5108902) Actinosynnema mirum DSM 43827 8328538 YP_003102039.1 CDS Amir_4342 NC_013093.1 5109178 5110428 D PFAM: sodium/hydrogen exchanger; KEGG: mxa:MXAN_0260 cation transporter/universal stress family protein; sodium/hydrogen exchanger 5109178..5110428 Actinosynnema mirum DSM 43827 8328539 YP_003102040.1 CDS Amir_4343 NC_013093.1 5110473 5110838 R KEGG: ade:Adeh_2705 response regulator receiver; hypothetical protein complement(5110473..5110838) Actinosynnema mirum DSM 43827 8328540 YP_003102041.1 CDS Amir_4344 NC_013093.1 5110835 5112637 R hypothetical protein complement(5110835..5112637) Actinosynnema mirum DSM 43827 8328541 YP_003102042.1 CDS Amir_4345 NC_013093.1 5112684 5113904 R TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bcb:BCB4264_A0206 drug resistance transporter, Bcr/CflA family; Bcr/CflA subfamily drug resistance transporter complement(5112684..5113904) Actinosynnema mirum DSM 43827 8328542 YP_003102043.1 CDS Amir_4346 NC_013093.1 5113941 5114384 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: dac:Daci_5402 transcriptional regulator, TrmB; MarR family transcriptional regulator 5113941..5114384 Actinosynnema mirum DSM 43827 8328543 YP_003102044.1 CDS Amir_4347 NC_013093.1 5114391 5117417 R SMART: ATPase AAA; KEGG: scl:sce3623 hypothetical protein; signal transduction protein with Nacht domain complement(5114391..5117417) Actinosynnema mirum DSM 43827 8328544 YP_003102045.1 CDS Amir_4348 NC_013093.1 5117476 5117958 R PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: rru:Rru_A3685 AsnC family transcriptional regulator; AsnC family transcriptional regulator complement(5117476..5117958) Actinosynnema mirum DSM 43827 8328545 YP_003102046.1 CDS Amir_4349 NC_013093.1 5118087 5118695 D PFAM: protein of unknown function DUF161; KEGG: rpi:Rpic_4668 protein of unknown function DUF161; hypothetical protein 5118087..5118695 Actinosynnema mirum DSM 43827 8328546 YP_003102047.1 CDS Amir_4350 NC_013093.1 5118772 5121582 R KEGG: nha:Nham_0826 hypothetical protein; hypothetical protein complement(5118772..5121582) Actinosynnema mirum DSM 43827 8328547 YP_003102048.1 CDS Amir_4351 NC_013093.1 5121845 5122534 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bxe:Bxe_A0699 two component transcriptional regulator; winged helix family two component transcriptional regulator 5121845..5122534 Actinosynnema mirum DSM 43827 8328548 YP_003102049.1 CDS Amir_4352 NC_013093.1 5122531 5123862 D PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ade:Adeh_2943 histidine kinase; histidine kinase 5122531..5123862 Actinosynnema mirum DSM 43827 8328549 YP_003102050.1 CDS Amir_4353 NC_013093.1 5123917 5125440 R PFAM: phenylalanine/histidine ammonia-lyase; KEGG: rsh:Rsph17029_1579 histidine ammonia-lyase; Histidine ammonia-lyase complement(5123917..5125440) Actinosynnema mirum DSM 43827 8328550 YP_003102051.1 CDS Amir_4354 NC_013093.1 5125504 5127054 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: RCJMB04_10a6, FOXRED2; FAD-dependent oxidoreductase domain containing 2; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 5125504..5127054 Actinosynnema mirum DSM 43827 8328551 YP_003102052.1 CDS Amir_4355 NC_013093.1 5127047 5128474 D PFAM: AMP-dependent synthetase and ligase; KEGG: vei:Veis_4674 acyl-CoA synthetase; AMP-dependent synthetase and ligase 5127047..5128474 Actinosynnema mirum DSM 43827 8328552 YP_003102053.1 CDS Amir_4356 NC_013093.1 5128550 5138752 R PFAM: KR domain protein; beta-ketoacyl synthase; acyl transferase; erythronolide synthase docking; short- chain dehydrogenase/reductase SDR; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase; KR domain-containing protein complement(5128550..5138752) Actinosynnema mirum DSM 43827 8328553 YP_003102054.1 CDS Amir_4357 NC_013093.1 5138804 5141272 R PFAM: beta-ketoacyl synthase; KEGG: eca:ECA0603 type I polyketide synthase; beta-ketoacyl synthase complement(5138804..5141272) Actinosynnema mirum DSM 43827 8328554 YP_003102055.1 CDS Amir_4358 NC_013093.1 5141269 5142612 R PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: scl:sce4847 hypothetical protein; FAD-binding monooxygenase complement(5141269..5142612) Actinosynnema mirum DSM 43827 8328555 YP_003102056.1 CDS Amir_4359 NC_013093.1 5142609 5152235 R PFAM: acyl transferase; KR domain protein; beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase complement(5142609..5152235) Actinosynnema mirum DSM 43827 8328556 YP_003102057.1 CDS Amir_4360 NC_013093.1 5152509 5153840 R PFAM: glycosyl transferase family 28; KEGG: ses:SARI_00205 hypothetical protein; glycosyl transferase family protein complement(5152509..5153840) Actinosynnema mirum DSM 43827 8328557 YP_003102058.1 CDS Amir_4361 NC_013093.1 5153954 5155189 R PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; KEGG: ses:SARI_00205 hypothetical protein; hypothetical protein complement(5153954..5155189) Actinosynnema mirum DSM 43827 8328558 YP_003102059.1 CDS Amir_4362 NC_013093.1 5155490 5156230 D PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: glo:Glov_3377 methyltransferase type 11; type 11 methyltransferase 5155490..5156230 Actinosynnema mirum DSM 43827 8328559 YP_003102060.1 CDS Amir_4363 NC_013093.1 5156329 5156628 R hypothetical protein complement(5156329..5156628) Actinosynnema mirum DSM 43827 8328560 YP_003102061.1 CDS Amir_4366 NC_013093.1 5157612 5158619 D KEGG: afw:Anae109_1986 extracellular HAF; hypothetical protein 5157612..5158619 Actinosynnema mirum DSM 43827 8328563 YP_003102062.1 CDS Amir_4367 NC_013093.1 5158663 5159640 R PFAM: 2-nitropropane dioxygenase NPD; KEGG: rpt:Rpal_2151 2-nitropropane dioxygenase NPD; 2-nitropropane dioxygenase NPD complement(5158663..5159640) Actinosynnema mirum DSM 43827 8328564 YP_003102063.1 CDS Amir_4368 NC_013093.1 5159653 5160795 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: IVD; IVD (ISOVALERYL-COA-DEHYDROGENASE); K00253 isovaleryl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein complement(5159653..5160795) Actinosynnema mirum DSM 43827 8328565 YP_003102064.1 CDS Amir_4369 NC_013093.1 5160829 5161449 R PFAM: regulatory protein TetR; KEGG: rpd:RPD_4359 regulatory protein, TetR; TetR family transcriptional regulator complement(5160829..5161449) Actinosynnema mirum DSM 43827 8328566 YP_003102065.1 CDS Amir_4370 NC_013093.1 5161497 5163302 R PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce8696 long-chain fatty-acid-- CoA ligase; AMP-dependent synthetase and ligase complement(5161497..5163302) Actinosynnema mirum DSM 43827 8328567 YP_003102066.1 CDS Amir_4371 NC_013093.1 5163548 5164756 D KEGG: mxa:MXAN_6988 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase 5163548..5164756 Actinosynnema mirum DSM 43827 8328568 YP_003102067.1 CDS Amir_4372 NC_013093.1 5164804 5166969 D PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: mxa:MXAN_6987 fatty oxidation complex, alpha subunit; 3-hydroxyacyl-CoA dehydrogenase 5164804..5166969 Actinosynnema mirum DSM 43827 8328569 YP_003102068.1 CDS Amir_4373 NC_013093.1 5166988 5167677 R PFAM: regulatory protein TetR; KEGG: sme:SMa2387 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(5166988..5167677) Actinosynnema mirum DSM 43827 8328570 YP_003102069.1 CDS Amir_4374 NC_013093.1 5167841 5169070 D KEGG: scl:sce5500 hypothetical protein; hypothetical protein 5167841..5169070 Actinosynnema mirum DSM 43827 8328571 YP_003102070.1 CDS Amir_4375 NC_013093.1 5169108 5170355 D KEGG: scl:sce5500 hypothetical protein; hypothetical protein 5169108..5170355 Actinosynnema mirum DSM 43827 8328572 YP_003102071.1 CDS Amir_4376 NC_013093.1 5170367 5172715 D PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mxa:MXAN_1752 isoquinoline 1-oxidoreductase, beta subunit; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 5170367..5172715 Actinosynnema mirum DSM 43827 8328573 YP_003102072.1 CDS Amir_4377 NC_013093.1 5172860 5173363 D PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: mxa:MXAN_1751 isoquinoline 1-oxidoreductase, alpha subunit; (2Fe-2S)-binding domain-containing protein 5172860..5173363 Actinosynnema mirum DSM 43827 8328574 YP_003102073.1 CDS Amir_4378 NC_013093.1 5173421 5174149 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: atc:AGR_pAT_269 hypothetical protein; MerR family transcriptional regulator complement(5173421..5174149) Actinosynnema mirum DSM 43827 8328575 YP_003102074.1 CDS Amir_4379 NC_013093.1 5175087 5176760 D PFAM: polyprenyl synthetase; KEGG: hne:HNE_0678 polyprenyl synthetase; polyprenyl synthetase 5175087..5176760 Actinosynnema mirum DSM 43827 8328576 YP_003102075.1 CDS Amir_4380 NC_013093.1 5176760 5177743 D PFAM: UbiA prenyltransferase; KEGG: bbt:BBta_6422 bacteriochlorophyll/chlorophyll a synthase; UbiA prenyltransferase 5176760..5177743 Actinosynnema mirum DSM 43827 8328577 YP_003102076.1 CDS Amir_4381 NC_013093.1 5177850 5179103 D PFAM: monooxygenase FAD-binding; glucose-inhibited division protein A; FAD dependent oxidoreductase; KEGG: bmn:BMA10247_A1734 monooxygenase; FAD-binding monooxygenase 5177850..5179103 Actinosynnema mirum DSM 43827 8328578 YP_003102077.1 CDS Amir_4382 NC_013093.1 5179112 5180104 R PFAM: O-methyltransferase; KEGG: sus:Acid_5654 hydroxyneurosporene-O- methyltransferase; O-methyltransferase complement(5179112..5180104) Actinosynnema mirum DSM 43827 8328579 YP_003102078.1 CDS Amir_4383 NC_013093.1 5180272 5181117 D PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: pla:Plav_2004 taurine dioxygenase; taurine dioxygenase 5180272..5181117 Actinosynnema mirum DSM 43827 8328580 YP_003102079.1 CDS Amir_4384 NC_013093.1 5181213 5182415 R PFAM: cytochrome P450; KEGG: bca:BCE_2654 cytochrome P450; cytochrome P450 complement(5181213..5182415) Actinosynnema mirum DSM 43827 8328581 YP_003102080.1 CDS Amir_4385 NC_013093.1 5182451 5184133 R PFAM: Prenyltransferase/squalene oxidase; KEGG: afw:Anae109_4079 squalene-hopene cyclase; Prenyltransferase/squalene oxidase complement(5182451..5184133) Actinosynnema mirum DSM 43827 8328582 YP_003102081.1 CDS Amir_4386 NC_013093.1 5184380 5185381 R PFAM: aminotransferase class I and II; KEGG: scl:sce8915 histidinol-phosphate transaminase; class I and II aminotransferase complement(5184380..5185381) Actinosynnema mirum DSM 43827 8328583 YP_003102082.1 CDS Amir_4387 NC_013093.1 5185962 5187251 D PFAM: major facilitator superfamily MFS_1; KEGG: floR; florfenicol/chloramphenicol resistance transporter protein; major facilitator superfamily protein 5185962..5187251 Actinosynnema mirum DSM 43827 8328584 YP_003102083.1 CDS Amir_4388 NC_013093.1 5187352 5187795 D KEGG: dal:Dalk_2807 hypothetical protein; hypothetical protein 5187352..5187795 Actinosynnema mirum DSM 43827 8328585 YP_003102084.1 CDS Amir_4389 NC_013093.1 5187921 5189153 R KEGG: mxa:MXAN_1195 hypothetical protein; hypothetical protein complement(5187921..5189153) Actinosynnema mirum DSM 43827 8328586 YP_003102085.1 CDS Amir_4390 NC_013093.1 5189293 5190555 R KEGG: bcz:BCZK1172 signal peptidase I; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24 and S26 domain protein; SMART: LamG domain protein jellyroll fold domain protein; peptidase S26B, signal peptidase complement(5189293..5190555) Actinosynnema mirum DSM 43827 8328587 YP_003102086.1 CDS Amir_4391 NC_013093.1 5190552 5191169 R KEGG: MUC1.3; hypothetical protein, likely cell wall localized and GPI-anchored mucin like; hypothetical protein complement(5190552..5191169) Actinosynnema mirum DSM 43827 8328588 YP_003102087.1 CDS Amir_4392 NC_013093.1 5191394 5191936 D PFAM: SCP-like extracellular; KEGG: noc:Noc_1373 hypothetical protein; SCP-like extracellular 5191394..5191936 Actinosynnema mirum DSM 43827 8328589 YP_003102088.1 CDS Amir_4393 NC_013093.1 5192055 5192795 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6740 AraC family transcriptional regulator; AraC family transcriptional regulator complement(5192055..5192795) Actinosynnema mirum DSM 43827 8328590 YP_003102089.1 CDS Amir_4394 NC_013093.1 5192871 5193431 D hypothetical protein 5192871..5193431 Actinosynnema mirum DSM 43827 8328591 YP_003102090.1 CDS Amir_4395 NC_013093.1 5193446 5194036 R PFAM: regulatory protein TetR; KEGG: mex:Mext_4360 regulatory protein TetR; TetR family transcriptional regulator complement(5193446..5194036) Actinosynnema mirum DSM 43827 8328592 YP_003102091.1 CDS Amir_4396 NC_013093.1 5194084 5194773 R PFAM: ThiJ/PfpI domain protein; KEGG: reu:Reut_A0026 ThiJ/PfpI; ThiJ/PfpI domain-containing protein complement(5194084..5194773) Actinosynnema mirum DSM 43827 8328593 YP_003102092.1 CDS Amir_4397 NC_013093.1 5194910 5195308 R hypothetical protein complement(5194910..5195308) Actinosynnema mirum DSM 43827 8328594 YP_003102093.1 CDS Amir_4398 NC_013093.1 5195346 5196095 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: esa:ESA_01962 hypothetical protein; short-chain dehydrogenase/reductase SDR complement(5195346..5196095) Actinosynnema mirum DSM 43827 8328595 YP_003102094.1 CDS Amir_4399 NC_013093.1 5196187 5196789 D PFAM: regulatory protein TetR; KEGG: afw:Anae109_3254 TetR family transcriptional regulator; TetR family transcriptional regulator 5196187..5196789 Actinosynnema mirum DSM 43827 8328596 YP_003102095.1 CDS Amir_4400 NC_013093.1 5196863 5197774 D PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; KEGG: har:HEAR1617 transcriptional regulator (CadR); MerR family transcriptional regulator 5196863..5197774 Actinosynnema mirum DSM 43827 8328597 YP_003102096.1 CDS Amir_4402 NC_013093.1 5198601 5199272 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: mes:Meso_2933 transcriptional regulator, GntR family; GntR family transcriptional regulator complement(5198601..5199272) Actinosynnema mirum DSM 43827 8328599 YP_003102097.1 CDS Amir_4403 NC_013093.1 5199382 5199906 D PFAM: PEBP family protein; KEGG: PEBP family protein; PEBP family protein 5199382..5199906 Actinosynnema mirum DSM 43827 8328600 YP_003102098.1 CDS Amir_4404 NC_013093.1 5200156 5203194 R KEGG: bur:Bcep18194_B1559 hypothetical protein; hypothetical protein complement(5200156..5203194) Actinosynnema mirum DSM 43827 8328601 YP_003102099.1 CDS Amir_4405 NC_013093.1 5203586 5204890 D PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_A3378 transcriptional regulator, AraC- family; AraC family transcriptional regulator 5203586..5204890 Actinosynnema mirum DSM 43827 8328602 YP_003102100.1 CDS Amir_4406 NC_013093.1 5204955 5205131 D hypothetical protein 5204955..5205131 Actinosynnema mirum DSM 43827 8328603 YP_003102101.1 CDS Amir_4407 NC_013093.1 5205155 5205538 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist; anti-sigma-factor antagonist 5205155..5205538 Actinosynnema mirum DSM 43827 8328604 YP_003102102.1 CDS Amir_4408 NC_013093.1 5205764 5206945 D PFAM: glycosyl transferase group 1; KEGG: cti:RALTA_A0583 glycosyl transferase, group 1; group 1 glycosyl transferase 5205764..5206945 Actinosynnema mirum DSM 43827 8328605 YP_003102103.1 CDS Amir_4409 NC_013093.1 5206949 5207920 R KEGG: lpc:LPC_2297 hypothetical protein; Mn2+dependent serine/threonine protein kinase complement(5206949..5207920) Actinosynnema mirum DSM 43827 8328606 YP_003102104.1 CDS Amir_4410 NC_013093.1 5207956 5208474 R KEGG: nar:Saro_3607 short-chain dehydrogenase/reductase SDR; hypothetical protein complement(5207956..5208474) Actinosynnema mirum DSM 43827 8328607 YP_003102105.1 CDS Amir_4412 NC_013093.1 5210003 5210428 D hypothetical protein 5210003..5210428 Actinosynnema mirum DSM 43827 8328609 YP_003102106.1 CDS Amir_4413 NC_013093.1 5210512 5210955 D PFAM: ferric-uptake regulator; KEGG: afw:Anae109_2251 ferric uptake regulator family protein; Fur family ferric uptake regulator 5210512..5210955 Actinosynnema mirum DSM 43827 8328610 YP_003102107.1 CDS Amir_4414 NC_013093.1 5211027 5211188 R TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; 50S ribosomal protein L32 complement(5211027..5211188) Actinosynnema mirum DSM 43827 8328611 YP_003102108.1 CDS Amir_4415 NC_013093.1 5211188 5211439 R TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: bha:BH3780 50S ribosomal protein L31 type B; 50S ribosomal protein L31 complement(5211188..5211439) Actinosynnema mirum DSM 43827 8328612 YP_003102109.1 CDS Amir_4416 NC_013093.1 5211436 5212527 R PFAM: cobalamin synthesis CobW domain protein; KEGG: bxe:Bxe_A4503 cobalamin synthesis protein/P47K; cobalamin synthesis CobW domain-containing protein complement(5211436..5212527) Actinosynnema mirum DSM 43827 8328613 YP_003102110.1 CDS Amir_4417 NC_013093.1 5212657 5214129 R PFAM: Catalase domain protein; KEGG: ppd:Ppro_1932 catalase; Catalase complement(5212657..5214129) Actinosynnema mirum DSM 43827 8328614 YP_003102111.1 CDS Amir_4418 NC_013093.1 5214277 5214951 D PFAM: glutamine amidotransferase class-I; KEGG: rpi:Rpic_0998 glutamine amidotransferase class-I; glutamine amidotransferase class-I 5214277..5214951 Actinosynnema mirum DSM 43827 8328615 YP_003102112.1 CDS Amir_4419 NC_013093.1 5214948 5215637 D PFAM: MOSC domain containing protein; KEGG: rsh:Rsph17029_0572 MOSC domain-containing protein; MOSC domain containing protein 5214948..5215637 Actinosynnema mirum DSM 43827 8328616 YP_003102113.1 CDS Amir_4420 NC_013093.1 5215696 5216241 D TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: oca:OCAR_6549 MIP; peroxidase-like protein 5215696..5216241 Actinosynnema mirum DSM 43827 8328617 YP_003102114.1 CDS Amir_4421 NC_013093.1 5216389 5216982 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: oca:OCAR_6548 transcriptional regulator, MarR family; MarR family transcriptional regulator 5216389..5216982 Actinosynnema mirum DSM 43827 8328618 YP_003102115.1 CDS Amir_4422 NC_013093.1 5216993 5217976 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: reh:H16_B0937 transcriptional regulator, AraC- family; AraC family transcriptional regulator complement(5216993..5217976) Actinosynnema mirum DSM 43827 8328619 YP_003102116.1 CDS Amir_4423 NC_013093.1 5218113 5219024 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mlo:mlr3236 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 5218113..5219024 Actinosynnema mirum DSM 43827 8328620 YP_003102117.1 CDS Amir_4424 NC_013093.1 5219040 5220053 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: cti:RALTA_B0761 transcriptional regulator, AraC family; AraC family transcriptional regulator complement(5219040..5220053) Actinosynnema mirum DSM 43827 8328621 YP_003102118.1 CDS Amir_4425 NC_013093.1 5220181 5221089 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mlo:mlr3236 oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 5220181..5221089 Actinosynnema mirum DSM 43827 8328622 YP_003102119.1 CDS Amir_4426 NC_013093.1 5221124 5222218 R PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: cti:RALTA_A2171 serine/threonine protein phosphatase, P2C family; protein serine/threonine phosphatase complement(5221124..5222218) Actinosynnema mirum DSM 43827 8328623 YP_003102120.1 CDS Amir_4428 NC_013093.1 5223000 5223938 R PFAM: NmrA family protein; KEGG: mxa:MXAN_7053 NmrA-like family protein; NmrA family protein complement(5223000..5223938) Actinosynnema mirum DSM 43827 8328625 YP_003102121.1 CDS Amir_4429 NC_013093.1 5224106 5224996 D PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: scl:sce1423 LysR family transcriptional regulator; LysR family transcriptional regulator 5224106..5224996 Actinosynnema mirum DSM 43827 8328626 YP_003102122.1 CDS Amir_4430 NC_013093.1 5225142 5225579 D PFAM: stress responsive alpha-beta barrel domain protein; stress responsive alpha-beta barrel domain-containing protein 5225142..5225579 Actinosynnema mirum DSM 43827 8328627 YP_003102123.1 CDS Amir_4431 NC_013093.1 5225576 5226634 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: ccs:CCNA_02209 quinone oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 5225576..5226634 Actinosynnema mirum DSM 43827 8328628 YP_003102124.1 CDS Amir_4432 NC_013093.1 5226631 5227197 D hypothetical protein 5226631..5227197 Actinosynnema mirum DSM 43827 8328629 YP_003102125.1 CDS Amir_4433 NC_013093.1 5227194 5227841 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(5227194..5227841) Actinosynnema mirum DSM 43827 8328630 YP_003102126.1 CDS Amir_4434 NC_013093.1 5227838 5228947 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: gdi:GDI1194 two-component system sensor protein; histidine kinase complement(5227838..5228947) Actinosynnema mirum DSM 43827 8328631 YP_003102127.1 CDS Amir_4435 NC_013093.1 5229068 5229256 D KEGG: bcr:BCAH187_A2835 HIT family hydrolase; HIT family hydrolase 5229068..5229256 Actinosynnema mirum DSM 43827 8328632 YP_003102128.1 CDS Amir_4436 NC_013093.1 5229934 5231376 D PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: reh:H16_A0856 L-amino-acid oxidase; amine oxidase 5229934..5231376 Actinosynnema mirum DSM 43827 8328633 YP_003102129.1 CDS Amir_4437 NC_013093.1 5231562 5232446 R PFAM: ABC transporter; KEGG: rpb:RPB_3405 hypothetical protein; ABC transporter complement(5231562..5232446) Actinosynnema mirum DSM 43827 8328634 YP_003102130.1 CDS Amir_4438 NC_013093.1 5232443 5233183 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: plu:plu2673 iron transport system ATP-binding protein YfeB; ABC transporter complement(5232443..5233183) Actinosynnema mirum DSM 43827 8328635 YP_003102131.1 CDS Amir_4439 NC_013093.1 5233180 5234094 R PFAM: periplasmic solute binding protein; KEGG: rsq:Rsph17025_0249 periplasmic solute binding protein; periplasmic solute binding protein complement(5233180..5234094) Actinosynnema mirum DSM 43827 8328636 YP_003102132.1 CDS Amir_4440 NC_013093.1 5234581 5240904 R TIGRFAM: thioester reductase domain protein; PFAM: short-chain dehydrogenase/reductase SDR; beta- ketoacyl synthase; Male sterility domain; KR domain protein; acyl transferase; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA0602 type I polyketide synthase; thioester reductase domain-containing protein complement(5234581..5240904) Actinosynnema mirum DSM 43827 8328637 YP_003102133.1 CDS Amir_4441 NC_013093.1 5240932 5249832 R PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase complement(5240932..5249832) Actinosynnema mirum DSM 43827 8328638 YP_003102134.1 CDS Amir_4442 NC_013093.1 5249837 5260849 R PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; erythronolide synthase docking; NAD- dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase; acyl transferase complement(5249837..5260849) Actinosynnema mirum DSM 43827 8328639 YP_003102135.1 CDS Amir_4443 NC_013093.1 5260871 5269414 R PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: eca:ECA0602 type I polyketide synthase; acyl transferase complement(5260871..5269414) Actinosynnema mirum DSM 43827 8328640 YP_003102136.1 CDS Amir_4444 NC_013093.1 5269440 5270756 R KEGG: bur:Bcep18194_C6844 regulator of polyketide synthase expression; PucR family transcriptional regulator complement(5269440..5270756) Actinosynnema mirum DSM 43827 8328641 YP_003102137.1 CDS Amir_4445 NC_013093.1 5270766 5272331 R PFAM: aminotransferase class-III; KEGG: ppu:PP_2782 pyridoxalphosphate dependent aminotransferase, class III; class III aminotransferase complement(5270766..5272331) Actinosynnema mirum DSM 43827 8328642 YP_003102138.1 CDS Amir_4446 NC_013093.1 5272505 5272870 D KEGG: pap:PSPA7_2619 hypothetical protein; hypothetical protein 5272505..5272870 Actinosynnema mirum DSM 43827 8328643 YP_003102139.1 CDS Amir_4447 NC_013093.1 5272944 5274140 R PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: pol:Bpro_2060 acyl-CoA dehydrogenase, C- terminal type2; acyl-CoA dehydrogenase type 2 domain-containing protein complement(5272944..5274140) Actinosynnema mirum DSM 43827 8328644 YP_003102140.1 CDS Amir_4448 NC_013093.1 5274353 5274850 D PFAM: flavin reductase domain protein FMN-binding; KEGG: nar:Saro_1462 flavin reductase-like, FMN- binding; flavin reductase domain-containing protein 5274353..5274850 Actinosynnema mirum DSM 43827 8328645 YP_003102141.1 CDS Amir_4449 NC_013093.1 5274895 5275356 R hypothetical protein complement(5274895..5275356) Actinosynnema mirum DSM 43827 8328646 YP_003102142.1 CDS Amir_4450 NC_013093.1 5275360 5276322 R PFAM: ribonucleotide reductase; KEGG: bba:Bd1983 ribonucleotide-diphosphate reductase small chain; ribonucleotide reductase complement(5275360..5276322) Actinosynnema mirum DSM 43827 8328647 YP_003102143.1 CDS Amir_4451 NC_013093.1 5276414 5277214 R PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: ade:Adeh_3289 SARP family transcriptional regulator; SARP family transcriptional regulator complement(5276414..5277214) Actinosynnema mirum DSM 43827 8328648 YP_003102144.1 CDS Amir_4452 NC_013093.1 5277705 5278862 R SMART: regulatory protein LuxR; KEGG: nha:Nham_1032 LuxR family transcriptional regulator; LuxR family transcriptional regulator complement(5277705..5278862) Actinosynnema mirum DSM 43827 8328649 YP_003102145.1 CDS Amir_4453 NC_013093.1 5279469 5280800 R PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: reh:H16_A0856 L-amino-acid oxidase; amine oxidase complement(5279469..5280800) Actinosynnema mirum DSM 43827 8328650 YP_003102146.1 CDS Amir_4454 NC_013093.1 5281007 5281852 R PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: rpd:RPD_2341 NmrA-like; NmrA family protein complement(5281007..5281852) Actinosynnema mirum DSM 43827 8328651 YP_003102147.1 CDS Amir_4455 NC_013093.1 5281933 5282892 D PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mno:Mnod_1588 transcriptional regulator, AraC family; AraC family transcriptional regulator 5281933..5282892 Actinosynnema mirum DSM 43827 8328652 YP_003102148.1 CDS Amir_4456 NC_013093.1 5282988 5283743 R PFAM: protein of unknown function DUF81; KEGG: sfu:Sfum_1521 protein of unknown function DUF81; hypothetical protein complement(5282988..5283743) Actinosynnema mirum DSM 43827 8328653 YP_003102149.1 CDS Amir_4457 NC_013093.1 5284250 5284561 D hypothetical protein 5284250..5284561 Actinosynnema mirum DSM 43827 8328654 YP_003102150.1 CDS Amir_4458 NC_013093.1 5284569 5285387 R SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; XRE family transcriptional regulator complement(5284569..5285387) Actinosynnema mirum DSM 43827 8328655 YP_003102151.1 CDS Amir_4459 NC_013093.1 5285392 5286303 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: xcv:XCV0256 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(5285392..5286303) Actinosynnema mirum DSM 43827 8328656 YP_003102152.1 CDS Amir_4460 NC_013093.1 5286406 5286870 R KEGG: bbt:BBta_5025 hypothetical protein; hypothetical protein complement(5286406..5286870) Actinosynnema mirum DSM 43827 8328657 YP_003102153.1 CDS Amir_4461 NC_013093.1 5286867 5287418 R PFAM: regulatory protein TetR; KEGG: bcz:BCZK4730 TetR family transcriptional regulator; TetR family transcriptional regulator complement(5286867..5287418) Actinosynnema mirum DSM 43827 8328658 YP_003102154.1 CDS Amir_4462 NC_013093.1 5287411 5288244 R PFAM: alpha/beta hydrolase fold; KEGG: hypothetical protein; alpha/beta hydrolase fold protein complement(5287411..5288244) Actinosynnema mirum DSM 43827 8328659 YP_003102155.1 CDS Amir_4463 NC_013093.1 5288447 5289106 D PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: afw:Anae109_2808 NADP oxidoreductase coenzyme F420-dependent; NADP oxidoreductase coenzyme F420-dependent 5288447..5289106 Actinosynnema mirum DSM 43827 8328660 YP_003102156.1 CDS Amir_4464 NC_013093.1 5289116 5289682 R PFAM: regulatory protein TetR; KEGG: atc:AGR_pAT_729 hypothetical protein; TetR family transcriptional regulator complement(5289116..5289682) Actinosynnema mirum DSM 43827 8328661 YP_003102157.1 CDS Amir_4465 NC_013093.1 5290060 5292159 R PFAM: oxidoreductase FAD-binding domain protein; pyridoxamine 5'-phosphate oxidase-related FMN-binding; ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: scl:sce7711 hypothetical protein; oxidoreductase FAD-binding domain-containing protein complement(5290060..5292159) Actinosynnema mirum DSM 43827 8328662 YP_003102158.1 CDS Amir_4466 NC_013093.1 5292246 5292860 D PFAM: regulatory protein TetR; KEGG: pla:Plav_1079 TetR family transcriptional regulator; TetR family transcriptional regulator 5292246..5292860 Actinosynnema mirum DSM 43827 8328663 YP_003102159.1 CDS Amir_4467 NC_013093.1 5293004 5293729 D KEGG: scl:sce9100 hypothetical protein; hypothetical protein 5293004..5293729 Actinosynnema mirum DSM 43827 8328664 YP_003102160.1 CDS Amir_4468 NC_013093.1 5293797 5295590 R PFAM: AMP-dependent synthetase and ligase; KEGG: afw:Anae109_0968 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase complement(5293797..5295590) Actinosynnema mirum DSM 43827 8328665 YP_003102161.1 CDS Amir_4469 NC_013093.1 5295830 5296171 D KEGG: similar to hyphally regulated cell wall protein HYR1p; hyphally regulated cell wall protein HYR1p-like protein 5295830..5296171 Actinosynnema mirum DSM 43827 8328666 YP_003102162.1 CDS Amir_4470 NC_013093.1 5296310 5296441 D hypothetical protein 5296310..5296441 Actinosynnema mirum DSM 43827 8328667 YP_003102163.1 CDS Amir_4471 NC_013093.1 5296524 5296820 R PFAM: Antibiotic biosynthesis monooxygenase; KEGG: jan:Jann_1295 antibiotic biosynthesis monooxygenase; Antibiotic biosynthesis monooxygenase complement(5296524..5296820) Actinosynnema mirum DSM 43827 8328668 YP_003102164.1 CDS Amir_4472 NC_013093.1 5296902 5297519 R PFAM: regulatory protein TetR; KEGG: xau:Xaut_2611 TetR family transcriptional regulator; TetR family transcriptional regulator complement(5296902..5297519) Actinosynnema mirum DSM 43827 8328669 YP_003102165.1 CDS Amir_4473 NC_013093.1 5297612 5298289 D PFAM: nitroreductase; KEGG: pla:Plav_2473 nitroreductase; nitroreductase 5297612..5298289 Actinosynnema mirum DSM 43827 8328670 YP_003102166.1 CDS Amir_4474 NC_013093.1 5298302 5298985 R hypothetical protein complement(5298302..5298985) Actinosynnema mirum DSM 43827 8328671 YP_003102167.1 CDS Amir_4475 NC_013093.1 5299045 5300217 R KEGG: rle:RL4432 hypothetical protein; hypothetical protein complement(5299045..5300217) Actinosynnema mirum DSM 43827 8328672 YP_003102168.1 CDS Amir_4477 NC_013093.1 5301065 5302810 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: pap:PSPA7_0145 serine/threonine protein kinase PpkA; serine/threonine protein kinase complement(5301065..5302810) Actinosynnema mirum DSM 43827 8328674 YP_003102169.1 CDS Amir_4479 NC_013093.1 5304179 5305330 D PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 5304179..5305330 Actinosynnema mirum DSM 43827 8328676 YP_003102170.1 CDS Amir_4480 NC_013093.1 5305327 5306661 D KEGG: rle:pRL120266 hypothetical protein; hypothetical protein 5305327..5306661 Actinosynnema mirum DSM 43827 8328677 YP_003102171.1 CDS Amir_4481 NC_013093.1 5306658 5307833 D PFAM: major facilitator superfamily MFS_1; KEGG: cvi:CV_1398 hypothetical protein; major facilitator superfamily protein 5306658..5307833 Actinosynnema mirum DSM 43827 8328678 YP_003102172.1 CDS Amir_4482 NC_013093.1 5307830 5308987 D PFAM: ROK family protein; KEGG: scl:sce7667 ROK family transcriptional regulator; ROK family protein 5307830..5308987 Actinosynnema mirum DSM 43827 8328679 YP_003102173.1 CDS Amir_4483 NC_013093.1 5309081 5309464 R KEGG: mpo:Mpop_1521 short-chain dehydrogenase/reductase SDR; hypothetical protein complement(5309081..5309464) Actinosynnema mirum DSM 43827 8328680 YP_003102174.1 CDS Amir_4484 NC_013093.1 5309496 5309918 R KEGG: bja:blr2505 hypothetical protein; hypothetical protein complement(5309496..5309918) Actinosynnema mirum DSM 43827 8328681 YP_003102175.1 CDS Amir_4485 NC_013093.1 5310025 5311170 R KEGG: ade:Adeh_2548 L-lysine 2,3-aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein complement(5310025..5311170) Actinosynnema mirum DSM 43827 8328682 YP_003102176.1 CDS Amir_4486 NC_013093.1 5311185 5316260 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: scl:sce8257 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(5311185..5316260) Actinosynnema mirum DSM 43827 8328683 YP_003102177.1 CDS Amir_4487 NC_013093.1 5316799 5317956 D PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: afw:Anae109_4239 monooxygenase FAD-binding; FAD-binding monooxygenase 5316799..5317956 Actinosynnema mirum DSM 43827 8328684 YP_003102178.1 CDS Amir_4488 NC_013093.1 5317992 5319260 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pen:PSEEN0980 L-ornithine 5-/L-lysine 6- monooxygenase; L-lysine 6-monooxygenase (NADPH) 5317992..5319260 Actinosynnema mirum DSM 43827 8328685 YP_003102179.1 CDS Amir_4489 NC_013093.1 5319270 5319926 D PFAM: Negative transcriptional regulator; KEGG: pmy:Pmen_0131 FMN-binding negative transcriptional regulator; FMN-binding negative transcriptional regulator 5319270..5319926 Actinosynnema mirum DSM 43827 8328686 YP_003102180.1 CDS Amir_4490 NC_013093.1 5319923 5321431 D TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: hch:HCH_03445 non-ribosomal peptide synthetase modules and related protein; amino acid adenylation domain-containing protein 5319923..5321431 Actinosynnema mirum DSM 43827 8328687 YP_003102181.1 CDS Amir_4491 NC_013093.1 5321478 5322749 R PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_2815 major facilitator transporter; major facilitator superfamily protein complement(5321478..5322749) Actinosynnema mirum DSM 43827 8328688 YP_003102182.1 CDS Amir_4492 NC_013093.1 5322746 5324695 R KEGG: rpe:RPE_0078 carbamoyltransferase; carbamoyl transferase NodU family-like protein complement(5322746..5324695) Actinosynnema mirum DSM 43827 8328689 YP_003102183.1 CDS Amir_4493 NC_013093.1 5324692 5325459 R PFAM: Thioesterase; KEGG: mxa:MXAN_4290 thioesterase; Thioesterase complement(5324692..5325459) Actinosynnema mirum DSM 43827 8328690 YP_003102184.1 CDS Amir_4494 NC_013093.1 5325437 5326720 R PFAM: cytochrome P450; KEGG: scl:sce7867 cytochrome P450 CYP124E1; cytochrome P450 complement(5325437..5326720) Actinosynnema mirum DSM 43827 8328691 YP_003102185.1 CDS Amir_4495 NC_013093.1 5326717 5328396 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: mxa:MXAN_4601 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein complement(5326717..5328396) Actinosynnema mirum DSM 43827 8328692 YP_003102186.1 CDS Amir_4496 NC_013093.1 5328398 5329090 R KEGG: bja:blr5743 hypothetical protein; hypothetical protein complement(5328398..5329090) Actinosynnema mirum DSM 43827 8328693 YP_003102187.1 CDS Amir_4497 NC_013093.1 5329090 5330094 R PFAM: GHMP kinase; KEGG: bvi:Bcep1808_5165 GHMP kinase; GHMP kinase complement(5329090..5330094) Actinosynnema mirum DSM 43827 8328694 YP_003102188.1 CDS Amir_4498 NC_013093.1 5330091 5335769 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3618 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(5330091..5335769) Actinosynnema mirum DSM 43827 8328695 YP_003102189.1 CDS Amir_4499 NC_013093.1 5335766 5336812 R PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: bpd:BURPS668_2111 L-allo-threonine aldolase; Threonine aldolase complement(5335766..5336812) Actinosynnema mirum DSM 43827 8328696 YP_003102190.1 CDS Amir_4500 NC_013093.1 5336809 5339079 R PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: bps:BPSL1715 argininosuccinate lyase; cysteine synthase complement(5336809..5339079) Actinosynnema mirum DSM 43827 8328697 YP_003102191.1 CDS Amir_4501 NC_013093.1 5339076 5340659 R PFAM: fumarate lyase; KEGG: rsq:Rsph17025_3642 hypothetical protein; fumarate lyase complement(5339076..5340659) Actinosynnema mirum DSM 43827 8328698 YP_003102192.1 CDS Amir_4502 NC_013093.1 5340656 5340871 R PFAM: MbtH domain protein; KEGG: rpc:RPC_1861 MbtH-like protein; MbtH domain-containing protein complement(5340656..5340871) Actinosynnema mirum DSM 43827 8328699 YP_003102193.1 CDS Amir_4503 NC_013093.1 5340885 5342804 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: aav:Aave_3731 amino acid adenylation domain; amino acid adenylation domain-containing protein complement(5340885..5342804) Actinosynnema mirum DSM 43827 8328700 YP_003102194.1 CDS Amir_4504 NC_013093.1 5343145 5343639 D hypothetical protein 5343145..5343639 Actinosynnema mirum DSM 43827 8328701 YP_003102195.1 CDS Amir_4505 NC_013093.1 5343682 5344965 D PFAM: condensation domain protein; KEGG: mxa:MXAN_4415 non-ribosomal peptide synthetase/polyketide synthase; condensation domain-containing protein 5343682..5344965 Actinosynnema mirum DSM 43827 8328702 YP_003102196.1 CDS Amir_4506 NC_013093.1 5344962 5346830 D TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: mxa:MXAN_3779 non-ribosomal peptide synthetase/polyketide synthase; amino acid adenylation domain-containing protein 5344962..5346830 Actinosynnema mirum DSM 43827 8328703 YP_003102197.1 CDS Amir_4507 NC_013093.1 5346994 5347242 D KEGG: mlo:mlr3218 hypothetical protein; hypothetical protein 5346994..5347242 Actinosynnema mirum DSM 43827 8328704 YP_003102198.1 CDS Amir_4508 NC_013093.1 5347572 5349653 D KEGG: bcz:BCZK2539 UvrD/Rep helicase family protein; superfamily I DNA and RNA helicase-like protein 5347572..5349653 Actinosynnema mirum DSM 43827 8328705 YP_003102199.1 CDS Amir_4509 NC_013093.1 5349713 5351884 R PFAM: MMPL domain protein; KEGG: bsu:BSU05430 hypothetical protein; MMPL domain-containing protein complement(5349713..5351884) Actinosynnema mirum DSM 43827 8328706 YP_003102200.1 CDS Amir_4510 NC_013093.1 5352063 5353289 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 5352063..5353289 Actinosynnema mirum DSM 43827 8328707 YP_003102201.1 CDS Amir_4511 NC_013093.1 5353286 5353966 D PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 5353286..5353966 Actinosynnema mirum DSM 43827 8328708 YP_003102202.1 CDS Amir_4512 NC_013093.1 5354019 5354672 D PFAM: VanZ family protein; KEGG: bha:BH2294 hypothetical protein; VanZ family protein 5354019..5354672 Actinosynnema mirum DSM 43827 8328709 YP_003102203.1 CDS Amir_4513 NC_013093.1 5354581 5355729 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sfu:Sfum_2006 integral membrane sensor signal transduction histidine kinase; histidine kinase complement(5354581..5355729) Actinosynnema mirum DSM 43827 8328710 YP_003102204.1 CDS Amir_4514 NC_013093.1 5355722 5356390 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sus:Acid_5477 two component transcriptional regulator; winged helix family two component transcriptional regulator complement(5355722..5356390) Actinosynnema mirum DSM 43827 8328711 YP_003102205.1 CDS Amir_4515 NC_013093.1 5356496 5357632 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: mxa:MXAN_5466 peptidase, S1E (streptogrisin A) subfamily; peptidase S1 and S6 chymotrypsin/Hap complement(5356496..5357632) Actinosynnema mirum DSM 43827 8328712 YP_003102206.1 CDS Amir_4516 NC_013093.1 5357935 5358984 D PFAM: cellulose-binding family II; lipolytic protein G-D-S-L family; SMART: cellulose-binding family II; KEGG: scl:sce7021 endoglucanase; cellulose-binding family protein 5357935..5358984 Actinosynnema mirum DSM 43827 8328713 YP_003102207.1 CDS Amir_4517 NC_013093.1 5359238 5359597 D hypothetical protein 5359238..5359597 Actinosynnema mirum DSM 43827 8328714 YP_003102208.1 CDS Amir_4518 NC_013093.1 5359594 5360172 D hypothetical protein 5359594..5360172 Actinosynnema mirum DSM 43827 8328715 YP_003102209.1 CDS Amir_4519 NC_013093.1 5360186 5361508 D KEGG: GG22683 gene product from transcript GG22683- RA; hypothetical protein 5360186..5361508 Actinosynnema mirum DSM 43827 8328716 YP_003102210.1 CDS Amir_4520 NC_013093.1 5361505 5362284 D KEGG: rru:Rru_A3404 TrkA domain-containing protein; hypothetical protein 5361505..5362284 Actinosynnema mirum DSM 43827 8328717 YP_003102211.1 CDS Amir_4521 NC_013093.1 5362294 5363166 R PFAM: alpha/beta hydrolase fold; KEGG: bsu:BSU03260 hypothetical protein; alpha/beta hydrolase fold protein complement(5362294..5363166) Actinosynnema mirum DSM 43827 8328718 YP_003102212.1 CDS Amir_4522 NC_013093.1 5363436 5364356 D KEGG: bsu:BSU02240 extracellular metalloprotease; extracellular metalloprotease 5363436..5364356 Actinosynnema mirum DSM 43827 8328719 YP_003102213.1 CDS Amir_4523 NC_013093.1 5364413 5364832 D PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: sit:TM1040_1898 twin-arginine translocation pathway signal; hypothetical protein 5364413..5364832 Actinosynnema mirum DSM 43827 8328720 YP_003102214.1 CDS Amir_4524 NC_013093.1 5364843 5365229 R hypothetical protein complement(5364843..5365229) Actinosynnema mirum DSM 43827 8328721 YP_003102215.1 CDS Amir_4526 NC_013093.1 5368097 5368786 R KEGG: Gpr125; G protein-coupled receptor 125; K08462 G protein-coupled receptor 125; hypothetical protein complement(5368097..5368786) Actinosynnema mirum DSM 43827 8328723 YP_003102216.1 CDS Amir_4527 NC_013093.1 5368783 5369091 R hypothetical protein complement(5368783..5369091) Actinosynnema mirum DSM 43827 8328724 YP_003102217.1 CDS Amir_4528 NC_013093.1 5369197 5370045 R hypothetical protein complement(5369197..5370045) Actinosynnema mirum DSM 43827 8328725 YP_003102218.1 CDS Amir_4529 NC_013093.1 5370211 5370645 R hypothetical protein complement(5370211..5370645) Actinosynnema mirum DSM 43827 8328726 YP_003102219.1 CDS Amir_4530 NC_013093.1 5370867 5371301 D hypothetical protein 5370867..5371301 Actinosynnema mirum DSM 43827 8328727 YP_003102220.1 CDS Amir_4531 NC_013093.1 5371621 5372274 D KEGG: rso:RS03147 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; PAS fold-4 domain protein; SMART: PAS domain containing protein; regulatory protein LuxR; LuxR family transcriptional regulator 5371621..5372274 Actinosynnema mirum DSM 43827 8328728 YP_003102221.1 CDS Amir_4532 NC_013093.1 5372300 5373301 D PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce5395 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 5372300..5373301 Actinosynnema mirum DSM 43827 8328729 YP_003102222.1 CDS Amir_4533 NC_013093.1 5373348 5374430 R hypothetical protein complement(5373348..5374430) Actinosynnema mirum DSM 43827 8328730 YP_003102223.1 CDS Amir_4534 NC_013093.1 5374427 5375422 R PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: hne:HNE_0812 oxidoreductase, NAD-binding; oxidoreductase domain-containing protein complement(5374427..5375422) Actinosynnema mirum DSM 43827 8328731 YP_003102224.1 CDS Amir_4535 NC_013093.1 5375412 5376671 R KEGG: scl:sce0971 hypothetical protein; hypothetical protein complement(5375412..5376671) Actinosynnema mirum DSM 43827 8328732 YP_003102225.1 CDS Amir_4536 NC_013093.1 5376668 5376964 R KEGG: sfu:Sfum_3460 acyl carrier protein; hypothetical protein complement(5376668..5376964) Actinosynnema mirum DSM 43827 8328733 YP_003102226.1 CDS Amir_4537 NC_013093.1 5376967 5378142 R PFAM: Radical SAM domain protein; KEGG: sfu:Sfum_2252 radical SAM domain protein; Radical SAM domain-containing protein complement(5376967..5378142) Actinosynnema mirum DSM 43827 8328734 YP_003102227.1 CDS Amir_4538 NC_013093.1 5378419 5379774 D PFAM: condensation domain protein; KEGG: bmn:BMA10247_A0621 peptide synthetase; condensation domain-containing protein 5378419..5379774 Actinosynnema mirum DSM 43827 8328735 YP_003102228.1 CDS Amir_4539 NC_013093.1 5379884 5380258 D hypothetical protein 5379884..5380258 Actinosynnema mirum DSM 43827 8328736 YP_003102229.1 CDS Amir_4541 NC_013093.1 5382947 5383078 R hypothetical protein complement(5382947..5383078) Actinosynnema mirum DSM 43827 8328738 YP_003102230.1 CDS Amir_4542 NC_013093.1 5383248 5383601 R hypothetical protein complement(5383248..5383601) Actinosynnema mirum DSM 43827 8328739 YP_003102231.1 CDS Amir_4543 NC_013093.1 5383588 5384067 R hypothetical protein complement(5383588..5384067) Actinosynnema mirum DSM 43827 8328740 YP_003102232.1 CDS Amir_4544 NC_013093.1 5384030 5388496 R TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; KEGG: rso:RS05482 rhs-related transmembrane protein; YD repeat-containing protein complement(5384030..5388496) Actinosynnema mirum DSM 43827 8328741 YP_003102233.1 CDS Amir_4545 NC_013093.1 5389116 5389673 D hypothetical protein 5389116..5389673 Actinosynnema mirum DSM 43827 8328743 YP_003102234.1 CDS Amir_4546 NC_013093.1 5389670 5390743 D PFAM: integrase family protein; KEGG: aeh:Mlg_1488 tyrosine recombinase XerD; integrase family protein 5389670..5390743 Actinosynnema mirum DSM 43827 8328744 YP_003102235.1 CDS Amir_4549 NC_013093.1 5391796 5393868 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; FG-GAP repeat protein; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: acp:A2cp1_3748 hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap complement(5391796..5393868) Actinosynnema mirum DSM 43827 8328747 YP_003102236.1 CDS Amir_4550 NC_013093.1 5393882 5397004 R PFAM: protein of unknown function DUF312; KEGG: SNF2 superfamily protein; methyl-accepting chemotaxis sensory transducer complement(5393882..5397004) Actinosynnema mirum DSM 43827 8328748 YP_003102237.1 CDS Amir_4551 NC_013093.1 5397643 5398521 D hypothetical protein 5397643..5398521 Actinosynnema mirum DSM 43827 8328749 YP_003102238.1 CDS Amir_4553 NC_013093.1 5400713 5401804 D KEGG: bxe:Bxe_A3516 transposase; transposase 5400713..5401804 Actinosynnema mirum DSM 43827 8328751 YP_003102239.1 CDS Amir_4554 NC_013093.1 5402015 5403241 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: afw:Anae109_3372 hypothetical protein; XRE family transcriptional regulator 5402015..5403241 Actinosynnema mirum DSM 43827 8328752 YP_003102240.1 CDS Amir_4555 NC_013093.1 5403341 5404459 D KEGG: mucin-associated surface protein (MASP); hypothetical protein 5403341..5404459 Actinosynnema mirum DSM 43827 8328753 YP_003102241.1 CDS Amir_4556 NC_013093.1 5405125 5406549 D KEGG: mca:MCA2681 hypothetical protein; hypothetical protein 5405125..5406549 Actinosynnema mirum DSM 43827 8328754 YP_003102242.1 CDS Amir_4557 NC_013093.1 5406539 5406775 R hypothetical protein complement(5406539..5406775) Actinosynnema mirum DSM 43827 8328755 YP_003102243.1 CDS Amir_4558 NC_013093.1 5406911 5408107 R hypothetical protein complement(5406911..5408107) Actinosynnema mirum DSM 43827 8328756 YP_003102244.1 CDS Amir_4559 NC_013093.1 5408444 5410147 R hypothetical protein complement(5408444..5410147) Actinosynnema mirum DSM 43827 8328757 YP_003102245.1 CDS Amir_4560 NC_013093.1 5410429 5410551 R hypothetical protein complement(5410429..5410551) Actinosynnema mirum DSM 43827 8328758 YP_003102246.1 CDS Amir_4561 NC_013093.1 5411020 5411121 D hypothetical protein 5411020..5411121 Actinosynnema mirum DSM 43827 8328759 YP_003102247.1 CDS Amir_4563 NC_013093.1 5411564 5412235 D hypothetical protein 5411564..5412235 Actinosynnema mirum DSM 43827 8328761 YP_003102248.1 CDS Amir_4564 NC_013093.1 5412561 5412857 D hypothetical protein 5412561..5412857 Actinosynnema mirum DSM 43827 8328762 YP_003102249.1 CDS Amir_4565 NC_013093.1 5413208 5413477 D hypothetical protein 5413208..5413477 Actinosynnema mirum DSM 43827 8328763 YP_003102250.1 CDS Amir_4566 NC_013093.1 5413733 5414206 D hypothetical protein 5413733..5414206 Actinosynnema mirum DSM 43827 8328764 YP_003102251.1 CDS Amir_4567 NC_013093.1 5414493 5415203 D KEGG: hypothetical protein LOC743833; hypothetical protein 5414493..5415203 Actinosynnema mirum DSM 43827 8328765 YP_003102252.1 CDS Amir_4568 NC_013093.1 5415562 5416518 D hypothetical protein 5415562..5416518 Actinosynnema mirum DSM 43827 8328766 YP_003102253.1 CDS Amir_4569 NC_013093.1 5416695 5416811 D hypothetical protein 5416695..5416811 Actinosynnema mirum DSM 43827 8328767 YP_003102254.1 CDS Amir_4570 NC_013093.1 5416932 5418176 D SMART: helix-turn-helix domain protein; KEGG: pin:Ping_0445 colicin uptake-like protein; XRE family transcriptional regulator 5416932..5418176 Actinosynnema mirum DSM 43827 8328768 YP_003102255.1 CDS Amir_4571 NC_013093.1 5418459 5419016 D hypothetical protein 5418459..5419016 Actinosynnema mirum DSM 43827 8328769 YP_003102256.1 CDS Amir_4572 NC_013093.1 5419291 5419461 D hypothetical protein 5419291..5419461 Actinosynnema mirum DSM 43827 8328770 YP_003102257.1 CDS Amir_4573 NC_013093.1 5419458 5420165 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pmy:Pmen_3998 phosphoglycolate phosphatase; HAD superfamily hydrolase 5419458..5420165 Actinosynnema mirum DSM 43827 8328771 YP_003102258.1 CDS Amir_4574 NC_013093.1 5420633 5421262 D hypothetical protein 5420633..5421262 Actinosynnema mirum DSM 43827 8328772 YP_003102259.1 CDS Amir_4575 NC_013093.1 5421259 5421969 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mno:Mnod_6944 phosphoglycolate phosphatase; HAD superfamily hydrolase 5421259..5421969 Actinosynnema mirum DSM 43827 8328773 YP_003102260.1 CDS Amir_4576 NC_013093.1 5422067 5423161 D KEGG: sus:Acid_3202 alpha/beta hydrolase fold; hypothetical protein 5422067..5423161 Actinosynnema mirum DSM 43827 8328774 YP_003102261.1 CDS Amir_4578 NC_013093.1 5424665 5425444 D PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein 5424665..5425444 Actinosynnema mirum DSM 43827 8328776 YP_003102262.1 CDS Amir_4580 NC_013093.1 5426251 5427441 D KEGG: numb; numb homolog (Drosophila); K06057 numb; hypothetical protein 5426251..5427441 Actinosynnema mirum DSM 43827 8328778 YP_003102263.1 CDS Amir_4584 NC_013093.1 5429735 5429995 R hypothetical protein complement(5429735..5429995) Actinosynnema mirum DSM 43827 8328782 YP_003102264.1 CDS Amir_4585 NC_013093.1 5430003 5434247 R KEGG: scl:sce2557 secreted protein; hypothetical protein complement(5430003..5434247) Actinosynnema mirum DSM 43827 8328783 YP_003102265.1 CDS Amir_4586 NC_013093.1 5434642 5435196 R PFAM: GCN5-related N-acetyltransferase; KEGG: kpn:KPN_01751 acetyltransferase; GCN5-like N-acetyltransferase complement(5434642..5435196) Actinosynnema mirum DSM 43827 8328784 YP_003102266.1 CDS Amir_4587 NC_013093.1 5435237 5436142 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: pfo:Pfl01_3628 hypothetical protein; type 11 methyltransferase complement(5435237..5436142) Actinosynnema mirum DSM 43827 8328785 YP_003102267.1 CDS Amir_4588 NC_013093.1 5436139 5441916 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: pap:PSPA7_2859 peptide synthase; amino acid adenylation domain-containing protein complement(5436139..5441916) Actinosynnema mirum DSM 43827 8328786 YP_003102268.1 CDS Amir_4589 NC_013093.1 5441913 5452958 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: dac:Daci_4753 amino acid adenylation domain- containing protein; amino acid adenylation domain-containing protein complement(5441913..5452958) Actinosynnema mirum DSM 43827 8328787 YP_003102269.1 CDS Amir_4590 NC_013093.1 5453084 5454121 D KEGG: sus:Acid_4167 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 4-hydroxyphenylpyruvate dioxygenase 5453084..5454121 Actinosynnema mirum DSM 43827 8328788 YP_003102270.1 CDS Amir_4591 NC_013093.1 5454137 5455432 D PFAM: aminotransferase class I and II; KEGG: hch:HCH_01676 transcriptional regulator; GntR family transcriptional regulator 5454137..5455432 Actinosynnema mirum DSM 43827 8328789 YP_003102271.1 CDS Amir_4592 NC_013093.1 5455474 5456700 R PFAM: major facilitator superfamily MFS_1; KEGG: kpe:KPK_3480 multidrug resistance protein MdtH; major facilitator superfamily protein complement(5455474..5456700) Actinosynnema mirum DSM 43827 8328790 YP_003102272.1 CDS Amir_4593 NC_013093.1 5456801 5457022 D PFAM: MbtH domain protein; KEGG: scl:sce3255 hypothetical protein; MbtH domain-containing protein 5456801..5457022 Actinosynnema mirum DSM 43827 8328791 YP_003102273.1 CDS Amir_4594 NC_013093.1 5457043 5458026 D PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mex:Mext_2357 D-cysteine desulfhydrase; pyridoxal-5'-phosphate-dependent protein beta subunit 5457043..5458026 Actinosynnema mirum DSM 43827 8328792 YP_003102274.1 CDS Amir_4595 NC_013093.1 5458029 5459063 D KEGG: bte:BTH_II0297 LpqC; poly(3-hydroxybutyrate) depolymerase-like protein 5458029..5459063 Actinosynnema mirum DSM 43827 8328793 YP_003102275.1 CDS Amir_4596 NC_013093.1 5459086 5460282 R PFAM: cytochrome P450; KEGG: rpd:RPD_0041 cytochrome P450; cytochrome P450 complement(5459086..5460282) Actinosynnema mirum DSM 43827 8328794 YP_003102276.1 CDS Amir_4597 NC_013093.1 5460312 5462060 R PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: scl:sce8759 hypothetical protein; SARP family transcriptional regulator complement(5460312..5462060) Actinosynnema mirum DSM 43827 8328795 YP_003102277.1 CDS Amir_4598 NC_013093.1 5462153 5463283 R PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: scl:sce7671 (S)-2-hydroxy-acid oxidase; FMN-dependent alpha-hydroxy acid dehydrogenase complement(5462153..5463283) Actinosynnema mirum DSM 43827 8328796 YP_003102278.1 CDS Amir_4599 NC_013093.1 5463890 5465227 R PFAM: cytochrome P450; KEGG: mxa:MXAN_2304 cytochrome P450 family protein; cytochrome P450 complement(5463890..5465227) Actinosynnema mirum DSM 43827 8328797 YP_003102279.1 CDS Amir_4600 NC_013093.1 5465375 5465596 R PFAM: MbtH domain protein; KEGG: cvi:CV_2232 MbtH-like protein; MbtH domain-containing protein complement(5465375..5465596) Actinosynnema mirum DSM 43827 8328798 YP_003102280.1 CDS Amir_4601 NC_013093.1 5465622 5466536 R KEGG: hypothetical protein; hypothetical protein complement(5465622..5466536) Actinosynnema mirum DSM 43827 8328799 YP_003102281.1 CDS Amir_4602 NC_013093.1 5466565 5467713 R PFAM: monooxygenase FAD-binding; KEGG: pag:PLES_17361 FAD-dependent monooxygenase; FAD-binding monooxygenase complement(5466565..5467713) Actinosynnema mirum DSM 43827 8328800 YP_003102282.1 CDS Amir_4603 NC_013093.1 5467710 5470019 R PFAM: short-chain dehydrogenase/reductase SDR; condensation domain protein; KEGG: pau:PA14_21000 hypothetical protein; short-chain dehydrogenase/reductase SDR complement(5467710..5470019) Actinosynnema mirum DSM 43827 8328801 YP_003102283.1 CDS Amir_4604 NC_013093.1 5470016 5483839 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; beta- ketoacyl synthase; alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; condensation domain protein; acyl transferase; KR domain protein; alcohol dehydrogenase zinc-binding domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pae:PA3327 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(5470016..5483839) Actinosynnema mirum DSM 43827 8328802 YP_003102284.1 CDS Amir_4605 NC_013093.1 5484257 5485666 D PFAM: cytochrome P450; KEGG: rde:RD1_3506 cytochrome P450 family protein; cytochrome P450 5484257..5485666 Actinosynnema mirum DSM 43827 8328803 YP_003102285.1 CDS Amir_4606 NC_013093.1 5485810 5487405 D PFAM: carboxylesterase type B; KEGG: rpe:RPE_0251 carboxylesterase, type B; carboxylesterase type B 5485810..5487405 Actinosynnema mirum DSM 43827 8328804 YP_003102286.1 CDS Amir_4607 NC_013093.1 5487844 5489091 R KEGG: scl:sce0661 mannan endo-1,4-beta-mannosidase; hypothetical protein complement(5487844..5489091) Actinosynnema mirum DSM 43827 8328805 YP_003102287.1 CDS Amir_4608 NC_013093.1 5489088 5490122 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: scl:sce0662 LacI family transcription regulator; LacI family transcriptional regulator complement(5489088..5490122) Actinosynnema mirum DSM 43827 8328806 YP_003102288.1 CDS Amir_4609 NC_013093.1 5490270 5491553 D PFAM: extracellular solute-binding protein family 1; KEGG: bha:BH3845 ABC transporter (substrate-binding protein); family 1 extracellular solute-binding protein 5490270..5491553 Actinosynnema mirum DSM 43827 8328807 YP_003102289.1 CDS Amir_4610 NC_013093.1 5491568 5492503 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlt:Rleg2_5350 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 5491568..5492503 Actinosynnema mirum DSM 43827 8328808 YP_003102290.1 CDS Amir_4611 NC_013093.1 5492525 5493376 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vei:Veis_0946 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 5492525..5493376 Actinosynnema mirum DSM 43827 8328809 YP_003102291.1 CDS Amir_4612 NC_013093.1 5493373 5495688 D PFAM: glycoside hydrolase family 3 domain protein; KEGG: sus:Acid_6936 glycoside hydrolase family 3 protein; glycoside hydrolase family protein 5493373..5495688 Actinosynnema mirum DSM 43827 8328810 YP_003102292.1 CDS Amir_4613 NC_013093.1 5495676 5496959 D PFAM: conserved hypothetical protein; KEGG: hypothetical LOC367592; K09704 hypothetical protein; hypothetical protein 5495676..5496959 Actinosynnema mirum DSM 43827 8328811 YP_003102293.1 CDS Amir_4614 NC_013093.1 5496964 5497632 R PFAM: regulatory protein TetR; KEGG: mlo:mll1924 transcription regulator; TetR family transcriptional regulator complement(5496964..5497632) Actinosynnema mirum DSM 43827 8328812 YP_003102294.1 CDS Amir_4615 NC_013093.1 5497778 5498956 D PFAM: monooxygenase FAD-binding; KEGG: sme:SMc02891 oxidoreductase transmembrane protein; FAD-binding monooxygenase 5497778..5498956 Actinosynnema mirum DSM 43827 8328813 YP_003102295.1 CDS Amir_4616 NC_013093.1 5499190 5500044 D KEGG: gur:Gura_2349 hypothetical protein; hypothetical protein 5499190..5500044 Actinosynnema mirum DSM 43827 8328814 YP_003102296.1 CDS Amir_4617 NC_013093.1 5500111 5500491 R hypothetical protein complement(5500111..5500491) Actinosynnema mirum DSM 43827 8328815 YP_003102297.1 CDS Amir_4618 NC_013093.1 5500749 5501987 D PFAM: major facilitator superfamily MFS_1; KEGG: pst:PSPTO_4522 hypothetical protein; major facilitator superfamily protein 5500749..5501987 Actinosynnema mirum DSM 43827 8328816 YP_003102298.1 CDS Amir_4619 NC_013093.1 5501991 5502794 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bpe:BP2854 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(5501991..5502794) Actinosynnema mirum DSM 43827 8328817 YP_003102299.1 CDS Amir_4620 NC_013093.1 5502890 5503474 D PFAM: regulatory protein TetR; KEGG: acp:A2cp1_2482 transcriptional regulator, TetR family; TetR family transcriptional regulator 5502890..5503474 Actinosynnema mirum DSM 43827 8328818 YP_003102300.1 CDS Amir_4621 NC_013093.1 5503602 5505095 D PFAM: Ricin B lectin; glycoside hydrolase family 5; SMART: Ricin B lectin; KEGG: scl:sce0748 Ricin precursor and poly(3- hydroxybutyrate) depolymerase fusion; Ricin B lectin 5503602..5505095 Actinosynnema mirum DSM 43827 8328819 YP_003102301.1 CDS Amir_4622 NC_013093.1 5505178 5505954 D PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: scl:sce7498 short chain dehydrogenase; short chain dehydrogenase 5505178..5505954 Actinosynnema mirum DSM 43827 8328820 YP_003102302.1 CDS Amir_4623 NC_013093.1 5505971 5506864 D PFAM: regulatory protein MerR; transcription activator effector binding; SMART: regulatory protein MerR; KEGG: cvi:CV_4236 MerR family transcriptional regulator; MerR family transcriptional regulator 5505971..5506864 Actinosynnema mirum DSM 43827 8328821 YP_003102303.1 CDS Amir_4624 NC_013093.1 5506842 5507843 R PFAM: regulatory protein MerR; PBS lyase HEAT domain protein repeat-containing protein; SMART: regulatory protein MerR; PBS lyase HEAT domain protein repeat-containing protein; KEGG: bur:Bcep18194_B2665 MerR family transcriptional regulator; MerR family transcriptional regulator complement(5506842..5507843) Actinosynnema mirum DSM 43827 8328822 YP_003102304.1 CDS Amir_4625 NC_013093.1 5507837 5508505 R KEGG: ppw:PputW619_5008 heat repeat-containing PBS lyase; hypothetical protein complement(5507837..5508505) Actinosynnema mirum DSM 43827 8328823 YP_003102305.1 CDS Amir_4626 NC_013093.1 5508825 5510438 D PFAM: AMP-dependent synthetase and ligase; KEGG: pzu:PHZ_c2512 long-chain-fatty-acid--CoA ligase; AMP-dependent synthetase and ligase 5508825..5510438 Actinosynnema mirum DSM 43827 8328824 YP_003102306.1 CDS Amir_4627 NC_013093.1 5510435 5511136 D KEGG: bsu:BSU35070 hypothetical protein; hypothetical protein 5510435..5511136 Actinosynnema mirum DSM 43827 8328825 YP_003102307.1 CDS Amir_4628 NC_013093.1 5511190 5511915 D PFAM: methyltransferase type 12; methyltransferase type 11; MCP methyltransferase CheR-type; KEGG: pfl:PFL_1036 ToxA protein; CheR-type MCP methyltransferase 5511190..5511915 Actinosynnema mirum DSM 43827 8328826 YP_003102308.1 CDS Amir_4630 NC_013093.1 5512855 5513184 R PFAM: protein of unknown function DUF1330; KEGG: pde:Pden_4583 protein of unknown function DUF1330; hypothetical protein complement(5512855..5513184) Actinosynnema mirum DSM 43827 8328828 YP_003102309.1 CDS Amir_4631 NC_013093.1 5513246 5514061 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: transcriptional regulator, XRE family; XRE family transcriptional regulator 5513246..5514061 Actinosynnema mirum DSM 43827 8328829 YP_003102310.1 CDS Amir_4632 NC_013093.1 5514078 5514965 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bpt:Bpet4146 LysR family transcriptional regulator; LysR family transcriptional regulator complement(5514078..5514965) Actinosynnema mirum DSM 43827 8328830 YP_003102311.1 CDS Amir_4633 NC_013093.1 5515035 5515982 D PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: met:M446_6836 threonine dehydratase; pyridoxal-5'-phosphate-dependent protein beta subunit 5515035..5515982 Actinosynnema mirum DSM 43827 8328831 YP_003102312.1 CDS Amir_4634 NC_013093.1 5516079 5520353 D PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 42 domain 5 loop region; glycosyl hydrolase family 98 carbohydrate binding module; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; SMART: glycosyl hydrolase family 98 carbohydrate binding module; LamG domain protein jellyroll fold domain protein; KEGG: sus:Acid_4607 beta-galactosidase; glycoside hydrolase family protein 5516079..5520353 Actinosynnema mirum DSM 43827 8328832 YP_003102313.1 CDS Amir_4635 NC_013093.1 5520406 5520819 R hypothetical protein complement(5520406..5520819) Actinosynnema mirum DSM 43827 8328833 YP_003102314.1 CDS Amir_4636 NC_013093.1 5520930 5521892 R PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_0902 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator complement(5520930..5521892) Actinosynnema mirum DSM 43827 8328834 YP_003102315.1 CDS Amir_4637 NC_013093.1 5522020 5522949 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: mlo:mlr2819 oxidoreductase; alcohol dehydrogenase GroES domain-containing protein complement(5522020..5522949) Actinosynnema mirum DSM 43827 8328835 YP_003102316.1 CDS Amir_4638 NC_013093.1 5523082 5523579 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bch:Bcen2424_4743 MarR family transcriptional regulator; MarR family transcriptional regulator 5523082..5523579 Actinosynnema mirum DSM 43827 8328836 YP_003102317.1 CDS Amir_4639 NC_013093.1 5523699 5525024 D PFAM: amino acid permease-associated region; KEGG: lpc:LPC_0052 amino acid transporter, permease; amino acid permease-associated protein 5523699..5525024 Actinosynnema mirum DSM 43827 8328837 YP_003102318.1 CDS Amir_4640 NC_013093.1 5525125 5525967 D KEGG: sat:SYN_02434 hydrolase or acyltransferase; hypothetical protein 5525125..5525967 Actinosynnema mirum DSM 43827 8328838 YP_003102319.1 CDS Amir_4641 NC_013093.1 5525964 5526656 D hypothetical protein 5525964..5526656 Actinosynnema mirum DSM 43827 8328839 YP_003102320.1 CDS Amir_4642 NC_013093.1 5526749 5527843 D PFAM: glycosyl transferase group 1; KEGG: gur:Gura_3220 glycosyl transferase, group 1; group 1 glycosyl transferase 5526749..5527843 Actinosynnema mirum DSM 43827 8328840 YP_003102321.1 CDS Amir_4643 NC_013093.1 5527860 5528660 D PFAM: glycosyl transferase family 2; KEGG: bcm:Bcenmc03_0849 glycosyl transferase family protein; family 2 glycosyl transferase 5527860..5528660 Actinosynnema mirum DSM 43827 8328841 YP_003102322.1 CDS Amir_4644 NC_013093.1 5529317 5529937 R hypothetical protein complement(5529317..5529937) Actinosynnema mirum DSM 43827 8328842 YP_003102323.1 CDS Amir_4645 NC_013093.1 5530090 5531103 R hypothetical protein complement(5530090..5531103) Actinosynnema mirum DSM 43827 8328843 YP_003102324.1 CDS Amir_4646 NC_013093.1 5531325 5532425 R TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: oca:OCAR_6856 alcohol dehydrogenase class 3; mycothiol-dependent formaldehyde dehydrogenase complement(5531325..5532425) Actinosynnema mirum DSM 43827 8328844 YP_003102325.1 CDS Amir_4647 NC_013093.1 5532742 5533992 D PFAM: major facilitator superfamily MFS_1; KEGG: reu:Reut_B3953 major facilitator transporter; major facilitator superfamily protein 5532742..5533992 Actinosynnema mirum DSM 43827 8328845 YP_003102326.1 CDS Amir_4648 NC_013093.1 5534320 5535534 D PFAM: protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: scl:sce5193 hypothetical protein; hypothetical protein 5534320..5535534 Actinosynnema mirum DSM 43827 8328846 YP_003102327.1 CDS Amir_4649 NC_013093.1 5535531 5536811 D PFAM: major facilitator superfamily MFS_1; KEGG: ank:AnaeK_4388 major facilitator superfamily MFS_1; major facilitator superfamily protein 5535531..5536811 Actinosynnema mirum DSM 43827 8328847 YP_003102328.1 CDS Amir_4650 NC_013093.1 5537170 5538774 D PFAM: AMP-dependent synthetase and ligase; KEGG: sdn:Sden_3736 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 5537170..5538774 Actinosynnema mirum DSM 43827 8328848 YP_003102329.1 CDS Amir_4651 NC_013093.1 5538818 5539066 D PFAM: phosphopantetheine-binding; KEGG: mxa:MXAN_3631 polyketide synthase type I; phosphopantetheine-binding 5538818..5539066 Actinosynnema mirum DSM 43827 8328849 YP_003102330.1 CDS Amir_4652 NC_013093.1 5539063 5540028 D PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bcy:Bcer98_3668 alpha/beta hydrolase domain- containing protein; alpha/beta hydrolase fold-3 domain-containing protein 5539063..5540028 Actinosynnema mirum DSM 43827 8328850 YP_003102331.1 CDS Amir_4653 NC_013093.1 5540074 5541123 R PFAM: transketolase; KEGG: bbt:BBta_4462 pyruvate dehydrogenase subunit beta; transketolase complement(5540074..5541123) Actinosynnema mirum DSM 43827 8328851 YP_003102332.1 CDS Amir_4654 NC_013093.1 5541120 5542514 R TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: reu:Reut_B5023 3-carboxy-cis,cis-muconate cycloisomerase; 3-carboxy-cis,cis-muconate cycloisomerase complement(5541120..5542514) Actinosynnema mirum DSM 43827 8328852 YP_003102333.1 CDS Amir_4655 NC_013093.1 5542504 5544816 R KEGG: hypothetical protein; hypothetical protein complement(5542504..5544816) Actinosynnema mirum DSM 43827 8328853 YP_003102334.1 CDS Amir_4656 NC_013093.1 5545289 5546032 D KEGG: bcz:BCZK1714 hypothetical protein; hypothetical protein 5545289..5546032 Actinosynnema mirum DSM 43827 8328854 YP_003102335.1 CDS Amir_4657 NC_013093.1 5546154 5547251 D KEGG: bja:blr1218 hypothetical protein; hypothetical protein 5546154..5547251 Actinosynnema mirum DSM 43827 8328855 YP_003102336.1 CDS Amir_4658 NC_013093.1 5547438 5548211 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: short chain dehydrogenase protein; short-chain dehydrogenase/reductase SDR 5547438..5548211 Actinosynnema mirum DSM 43827 8328856 YP_003102337.1 CDS Amir_4659 NC_013093.1 5548489 5549208 D hypothetical protein 5548489..5549208 Actinosynnema mirum DSM 43827 8328857 YP_003102338.1 CDS Amir_4660 NC_013093.1 5549427 5550164 D PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: dps:DP1551 hypothetical protein; nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase 5549427..5550164 Actinosynnema mirum DSM 43827 8328858 YP_003102339.1 CDS Amir_4661 NC_013093.1 5550161 5551153 D PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: bcy:Bcer98_3668 alpha/beta hydrolase domain- containing protein; alpha/beta hydrolase fold-3 domain-containing protein 5550161..5551153 Actinosynnema mirum DSM 43827 8328859 YP_003102340.1 CDS Amir_4662 NC_013093.1 5551387 5552238 D KEGG: xcb:XC_3673 hypothetical protein; hypothetical protein 5551387..5552238 Actinosynnema mirum DSM 43827 8328860 YP_003102341.1 CDS Amir_4663 NC_013093.1 5552303 5553307 R PFAM: pectinesterase; KEGG: xop:PXO_00373 pectinesterase; pectinesterase complement(5552303..5553307) Actinosynnema mirum DSM 43827 8328861 YP_003102342.1 CDS Amir_4664 NC_013093.1 5553359 5554216 R PFAM: lipolytic protein G-D-S-L family; KEGG: bsu:BSU07020 hypothetical protein; G-D-S-L family lipolytic protein complement(5553359..5554216) Actinosynnema mirum DSM 43827 8328862 YP_003102343.1 CDS Amir_4665 NC_013093.1 5554572 5554952 D PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rlt:Rleg2_1526 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase 5554572..5554952 Actinosynnema mirum DSM 43827 8328863 YP_003102344.1 CDS Amir_4666 NC_013093.1 5555206 5555433 R KEGG: bha:BH0581 two-component response regulator; response regulator receiver protein complement(5555206..5555433) Actinosynnema mirum DSM 43827 8328864 YP_003102345.1 CDS Amir_4667 NC_013093.1 5555468 5555851 R hypothetical protein complement(5555468..5555851) Actinosynnema mirum DSM 43827 8328865 YP_003102346.1 CDS Amir_4668 NC_013093.1 5555848 5556288 R KEGG: ilo:IL0311 ABC-type multidrug transport system, permease component; multidrug ABC transporter permease complement(5555848..5556288) Actinosynnema mirum DSM 43827 8328866 YP_003102347.1 CDS Amir_4669 NC_013093.1 5556285 5556860 R PFAM: ABC transporter; KEGG: ccs:CCNA_01205 ABC transporter ATP-binding protein; ABC transporter ATP-binding protein complement(5556285..5556860) Actinosynnema mirum DSM 43827 8328867 YP_003102348.1 CDS Amir_4670 NC_013093.1 5556986 5557879 D KEGG: atc:AGR_pAT_397 hypothetical protein; hypothetical protein 5556986..5557879 Actinosynnema mirum DSM 43827 8328868 YP_003102349.1 CDS Amir_4671 NC_013093.1 5557876 5558739 D PFAM: luciferase-like monooxygenase; KEGG: bcj:BCAM1565 monooxygenase; luciferase-like monooxygenase 5557876..5558739 Actinosynnema mirum DSM 43827 8328869 YP_003102350.1 CDS Amir_4672 NC_013093.1 5558860 5559504 D KEGG: sun:SUN_0435 hypothetical protein; hypothetical protein 5558860..5559504 Actinosynnema mirum DSM 43827 8328870 YP_003102351.1 CDS Amir_4673 NC_013093.1 5559679 5560674 D PFAM: lipolytic protein G-D-S-L family; KEGG: hypothetical protein; G-D-S-L family lipolytic protein 5559679..5560674 Actinosynnema mirum DSM 43827 8328871 YP_003102352.1 CDS Amir_4674 NC_013093.1 5560676 5561680 D PFAM: lipolytic protein G-D-S-L family; KEGG: scl:sce5722 endo-1,4-beta-glucanase; G-D-S-L family lipolytic protein 5560676..5561680 Actinosynnema mirum DSM 43827 8328872 YP_003102353.1 CDS Amir_4675 NC_013093.1 5561700 5561861 D hypothetical protein 5561700..5561861 Actinosynnema mirum DSM 43827 8328873 YP_003102354.1 CDS Amir_4676 NC_013093.1 5561862 5562215 R KEGG: scl:sce8365 hypothetical protein; hypothetical protein complement(5561862..5562215) Actinosynnema mirum DSM 43827 8328874 YP_003102355.1 CDS Amir_4677 NC_013093.1 5562291 5562440 R hypothetical protein complement(5562291..5562440) Actinosynnema mirum DSM 43827 8328875 YP_003102356.1 CDS Amir_4678 NC_013093.1 5562458 5563105 D KEGG: abo:ABO_1927 hypothetical protein; hypothetical protein 5562458..5563105 Actinosynnema mirum DSM 43827 8328876 YP_003102357.1 CDS Amir_4679 NC_013093.1 5563107 5564879 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_5176 serine/threonine protein kinase; serine/threonine protein kinase complement(5563107..5564879) Actinosynnema mirum DSM 43827 8328877 YP_003102358.1 CDS Amir_4682 NC_013093.1 5566698 5568479 D PFAM: cellulose-binding family II; SMART: cellulose-binding family II; KEGG: ccs:CCNA_03254 pectate lyase; cellulose-binding family protein 5566698..5568479 Actinosynnema mirum DSM 43827 8328880 YP_003102359.1 CDS Amir_4683 NC_013093.1 5568526 5569683 R PFAM: regulatory protein TetR; KEGG: cvi:CV_0711 TetR family transcriptional regulator; TetR family transcriptional regulator complement(5568526..5569683) Actinosynnema mirum DSM 43827 8328881 YP_003102360.1 CDS Amir_4684 NC_013093.1 5569905 5571485 D PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA2050 ADP-producing CoA ligase, feruloyl-CoA synthetase; AMP-dependent synthetase and ligase 5569905..5571485 Actinosynnema mirum DSM 43827 8328882 YP_003102361.1 CDS gabD2 NC_013093.1 5571598 5573214 R NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase complement(5571598..5573214) Actinosynnema mirum DSM 43827 8328883 YP_003102362.1 CDS Amir_4686 NC_013093.1 5573387 5574598 D KEGG: scl:sce5500 hypothetical protein; hypothetical protein 5573387..5574598 Actinosynnema mirum DSM 43827 8328884 YP_003102363.1 CDS Amir_4687 NC_013093.1 5574765 5575886 D PFAM: beta-lactamase; KEGG: scl:sce3869 hypothetical protein; Serine-type D-Ala-D-Ala carboxypeptidase 5574765..5575886 Actinosynnema mirum DSM 43827 8328885 YP_003102364.1 CDS Amir_4688 NC_013093.1 5575877 5577136 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: bme:BMEI1583 sensor protein DegS; histidine kinase 5575877..5577136 Actinosynnema mirum DSM 43827 8328886 YP_003102365.1 CDS Amir_4689 NC_013093.1 5577124 5577774 D PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; response regulator receiver; KEGG: bsu:BSU08300 hypothetical protein; LuxR family transcriptional regulator 5577124..5577774 Actinosynnema mirum DSM 43827 8328887 YP_003102366.1 CDS Amir_4690 NC_013093.1 5577789 5577884 D hypothetical protein 5577789..5577884 Actinosynnema mirum DSM 43827 8328888 YP_003102367.1 CDS Amir_4691 NC_013093.1 5577939 5579090 R PFAM: beta-lactamase; KEGG: scl:sce3868 alkaline D-peptidase; Serine-type D-Ala-D-Ala carboxypeptidase complement(5577939..5579090) Actinosynnema mirum DSM 43827 8328889 YP_003102368.1 CDS Amir_4692 NC_013093.1 5579180 5580208 R KEGG: eba:ebA5037 hypothetical protein; hypothetical protein complement(5579180..5580208) Actinosynnema mirum DSM 43827 8328890 YP_003102369.1 CDS Amir_4693 NC_013093.1 5580423 5581085 D PFAM: chitin-binding domain 3 protein; KEGG: cvi:CV_0554 carbohydrate-binding protein; chitin-binding domain 3 protein 5580423..5581085 Actinosynnema mirum DSM 43827 8328891 YP_003102370.1 CDS Amir_4694 NC_013093.1 5581888 5584389 D PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: sme:SMa0464 adenylate/guanylate cyclase; SARP family transcriptional regulator 5581888..5584389 Actinosynnema mirum DSM 43827 8328892 YP_003102371.1 CDS Amir_4695 NC_013093.1 5584548 5586101 D PFAM: aminotransferase class-III; KEGG: ppu:PP_2782 pyridoxalphosphate dependent aminotransferase, class III; class III aminotransferase 5584548..5586101 Actinosynnema mirum DSM 43827 8328893 YP_003102372.1 CDS Amir_4696 NC_013093.1 5586098 5587270 D PFAM: acyl-CoA dehydrogenase domain protein; KEGG: bsu:BSU18260 hypothetical protein; acyl-CoA dehydrogenase domain-containing protein 5586098..5587270 Actinosynnema mirum DSM 43827 8328894 YP_003102373.1 CDS Amir_4697 NC_013093.1 5587362 5587769 R KEGG: pap:PSPA7_2619 hypothetical protein; hypothetical protein complement(5587362..5587769) Actinosynnema mirum DSM 43827 8328895 YP_003102374.1 CDS Amir_4698 NC_013093.1 5587851 5594192 R TIGRFAM: thioester reductase domain protein; PFAM: Male sterility domain; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; 3- beta hydroxysteroid dehydrogenase/isomerase; acyl transferase; KR domain protein; erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: pst:PSPTO_4687 coronafacic acid polyketide synthetase II; thioester reductase domain-containing protein complement(5587851..5594192) Actinosynnema mirum DSM 43827 8328896 YP_003102375.1 CDS Amir_4699 NC_013093.1 5594239 5606481 R PFAM: acyl transferase; short-chain dehydrogenase/reductase SDR; beta-ketoacyl synthase; KR domain protein; phosphopantetheine-binding; KEGG: met:M446_0170 beta-ketoacyl synthase; Mycocerosate synthase., erythronolide synthase complement(5594239..5606481) Actinosynnema mirum DSM 43827 8328897 YP_003102376.1 CDS Amir_4700 NC_013093.1 5606723 5607262 D PFAM: flavin reductase domain protein FMN-binding; KEGG: bpy:Bphyt_1723 flavin reductase domain protein FMN-binding; flavin reductase domain-containing protein 5606723..5607262 Actinosynnema mirum DSM 43827 8328898 YP_003102377.1 CDS Amir_4701 NC_013093.1 5607479 5608024 D PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 5607479..5608024 Actinosynnema mirum DSM 43827 8328899 YP_003102378.1 CDS Amir_4702 NC_013093.1 5608166 5609017 R PFAM: NmrA family protein; KEGG: afw:Anae109_3754 NmrA family protein; NmrA family protein complement(5608166..5609017) Actinosynnema mirum DSM 43827 8328900 YP_003102379.1 CDS Amir_4703 NC_013093.1 5609217 5610398 R PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: rsh:Rsph17029_3744 acyl-CoA dehydrogenase type 2; acyl-CoA dehydrogenase type 2 domain-containing protein complement(5609217..5610398) Actinosynnema mirum DSM 43827 8328901 YP_003102380.1 CDS Amir_4704 NC_013093.1 5610713 5612149 R PFAM: major facilitator superfamily MFS_1; KEGG: transporter protein; major facilitator superfamily protein complement(5610713..5612149) Actinosynnema mirum DSM 43827 8328902 YP_003102381.1 CDS Amir_4705 NC_013093.1 5612274 5612720 D PFAM: helix-turn-helix HxlR type; KEGG: hypothetical protein; HxlR family transcriptional regulator 5612274..5612720 Actinosynnema mirum DSM 43827 8328903 YP_003102382.1 CDS Amir_4706 NC_013093.1 5612783 5613184 R KEGG: pap:PSPA7_2619 hypothetical protein; hypothetical protein complement(5612783..5613184) Actinosynnema mirum DSM 43827 8328904 YP_003102383.1 CDS Amir_4707 NC_013093.1 5613245 5614432 R PFAM: acyl-CoA dehydrogenase type 2 domain; acyl- CoA dehydrogenase domain protein; KEGG: rlt:Rleg2_5725 acyl-CoA dehydrogenase type 2 domain; acyl-CoA dehydrogenase type 2 domain-containing protein complement(5613245..5614432) Actinosynnema mirum DSM 43827 8328905 YP_003102384.1 CDS Amir_4708 NC_013093.1 5614664 5615083 D KEGG: sus:Acid_5966 hypothetical protein; hypothetical protein 5614664..5615083 Actinosynnema mirum DSM 43827 8328906 YP_003102385.1 CDS Amir_4709 NC_013093.1 5615253 5615618 D KEGG: aav:Aave_2096 transcriptional regulator, ArsR family; hypothetical protein 5615253..5615618 Actinosynnema mirum DSM 43827 8328907 YP_003102386.1 CDS Amir_4710 NC_013093.1 5615801 5617315 R PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: sde:Sde_0644 hypothetical protein; TAP domain-containing protein complement(5615801..5617315) Actinosynnema mirum DSM 43827 8328908 YP_003102387.1 CDS Amir_4711 NC_013093.1 5617627 5619573 R KEGG: rme:Rmet_4641 ATP-dependent endonuclease of the OLD family-like protein; ATP-dependent endonuclease of the OLD family- like protein complement(5617627..5619573) Actinosynnema mirum DSM 43827 8328909 YP_003102388.1 CDS Amir_4712 NC_013093.1 5619780 5622425 R PFAM: protein of unknown function DUF1680; KEGG: hypothetical protein; hypothetical protein complement(5619780..5622425) Actinosynnema mirum DSM 43827 8328910 YP_003102389.1 CDS Amir_4713 NC_013093.1 5622422 5623783 R PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: scl:sce8667 hypothetical protein; Xaa-Pro aminopeptidase complement(5622422..5623783) Actinosynnema mirum DSM 43827 8328911 YP_003102390.1 CDS Amir_4714 NC_013093.1 5623794 5625113 R PFAM: alpha/beta hydrolase fold; KEGG: rle:pRL100270 proline iminopeptidase; alpha/beta hydrolase fold protein complement(5623794..5625113) Actinosynnema mirum DSM 43827 8328912 YP_003102391.1 CDS Amir_4715 NC_013093.1 5625110 5626090 R PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: dol:Dole_0940 oligopeptide/dipeptide ABC transporter, ATPase subunit; ABC transporter complement(5625110..5626090) Actinosynnema mirum DSM 43827 8328913 YP_003102392.1 CDS Amir_4716 NC_013093.1 5626087 5626902 R PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: bja:bll2870 ABC transporter ATP-binding protein; ABC transporter complement(5626087..5626902) Actinosynnema mirum DSM 43827 8328914 YP_003102393.1 CDS Amir_4717 NC_013093.1 5626899 5627897 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: peptide transport system permease protein; K02033 peptide/nickel transport system permease protein; ABC transporter inner membrane protein complement(5626899..5627897) Actinosynnema mirum DSM 43827 8328915 YP_003102394.1 CDS Amir_4718 NC_013093.1 5627894 5628850 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: gme:Gmet_1236 binding-protein dependent transport system inner membrane protein; ABC transporter inner membrane protein complement(5627894..5628850) Actinosynnema mirum DSM 43827 8328916 YP_003102395.1 CDS Amir_4719 NC_013093.1 5628855 5630549 R PFAM: extracellular solute-binding protein family 5; KEGG: rle:pRL110448 substrate-binding ABC transporter protein; 4-phytase complement(5628855..5630549) Actinosynnema mirum DSM 43827 8328917 YP_003102396.1 CDS Amir_4720 NC_013093.1 5631077 5631748 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bbr:BB0470 GntR family transcriptional regulator; GntR family transcriptional regulator complement(5631077..5631748) Actinosynnema mirum DSM 43827 8328918 YP_003102397.1 CDS Amir_4721 NC_013093.1 5631866 5633239 R PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_02881 oxoglutarate semialdehyde dehydrogenase; aldehyde dehydrogenase complement(5631866..5633239) Actinosynnema mirum DSM 43827 8328919 YP_003102398.1 CDS Amir_4722 NC_013093.1 5633250 5634251 R PFAM: proline racemase; KEGG: bat:BAS2643 proline racemase; proline racemase complement(5633250..5634251) Actinosynnema mirum DSM 43827 8328920 YP_003102399.1 CDS Amir_4723 NC_013093.1 5634253 5635185 R PFAM: dihydrodipicolinate synthetase; KEGG: swd:Swoo_2822 dihydrodipicolinate synthetase; dihydrodipicolinate synthetase complement(5634253..5635185) Actinosynnema mirum DSM 43827 8328921 YP_003102400.1 CDS Amir_4724 NC_013093.1 5635182 5636585 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: bph:Bphy_4670 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(5635182..5636585) Actinosynnema mirum DSM 43827 8328922 YP_003102401.1 CDS Amir_4725 NC_013093.1 5636578 5636835 R KEGG: vei:Veis_0721 FAD dependent oxidoreductase; FAD dependent oxidoreductase complement(5636578..5636835) Actinosynnema mirum DSM 43827 8328923 YP_003102402.1 CDS Amir_4726 NC_013093.1 5636832 5638001 R PFAM: FAD dependent oxidoreductase; KEGG: bce:BC2836 sarcosine oxidase beta subunit; FAD dependent oxidoreductase complement(5636832..5638001) Actinosynnema mirum DSM 43827 8328924 YP_003102403.1 CDS Amir_4727 NC_013093.1 5638415 5638918 R hypothetical protein complement(5638415..5638918) Actinosynnema mirum DSM 43827 8328925 YP_003102404.1 CDS Amir_4728 NC_013093.1 5639694 5640359 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5639694..5640359 Actinosynnema mirum DSM 43827 8328926 YP_003102405.1 CDS Amir_4729 NC_013093.1 5640505 5641533 D PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: bac:BamMC406_6022 LacI family transcription regulator; LacI family transcriptional regulator 5640505..5641533 Actinosynnema mirum DSM 43827 8328927 YP_003102406.1 CDS deoA NC_013093.1 5641562 5642863 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5641562..5642863 Actinosynnema mirum DSM 43827 8328928 YP_003102407.1 CDS Amir_4731 NC_013093.1 5643007 5644479 D PFAM: amidohydrolase; Amidohydrolase 3; KEGG: scl:sce1158 hypothetical protein; amidohydrolase 5643007..5644479 Actinosynnema mirum DSM 43827 8328929 YP_003102408.1 CDS Amir_4732 NC_013093.1 5644553 5645908 R KEGG: glycosyl hydrolase family 10 protein; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase complement(5644553..5645908) Actinosynnema mirum DSM 43827 8328930 YP_003102409.1 CDS Amir_4733 NC_013093.1 5646080 5646982 R hypothetical protein complement(5646080..5646982) Actinosynnema mirum DSM 43827 8328931 YP_003102410.1 CDS Amir_4734 NC_013093.1 5647196 5647891 D hypothetical protein 5647196..5647891 Actinosynnema mirum DSM 43827 8328932 YP_003102411.1 CDS Amir_4735 NC_013093.1 5647888 5648655 D KEGG: ade:Adeh_2319 hypothetical protein; hypothetical protein 5647888..5648655 Actinosynnema mirum DSM 43827 8328933 YP_003102412.1 CDS Amir_4737 NC_013093.1 5649397 5649846 R KEGG: pzu:PHZ_c0663 type II secretion system protein N; hypothetical protein complement(5649397..5649846) Actinosynnema mirum DSM 43827 8328935 YP_003102413.1 CDS Amir_4738 NC_013093.1 5649849 5651000 R KEGG: smd:Smed_1835 hypothetical protein; hypothetical protein complement(5649849..5651000) Actinosynnema mirum DSM 43827 8328936 YP_003102414.1 CDS Amir_4739 NC_013093.1 5651000 5651296 R hypothetical protein complement(5651000..5651296) Actinosynnema mirum DSM 43827 8328937 YP_003102415.1 CDS Amir_4740 NC_013093.1 5651559 5652407 R KEGG: ank:AnaeK_3866 hypothetical protein; hypothetical protein complement(5651559..5652407) Actinosynnema mirum DSM 43827 8328938 YP_003102416.1 CDS Amir_4741 NC_013093.1 5652530 5653096 R KEGG: pna:Pnap_3074 hypothetical protein; hypothetical protein complement(5652530..5653096) Actinosynnema mirum DSM 43827 8328939 YP_003102417.1 CDS Amir_4742 NC_013093.1 5653093 5654448 R KEGG: ank:AnaeK_1466 hypothetical protein; hypothetical protein complement(5653093..5654448) Actinosynnema mirum DSM 43827 8328940 YP_003102418.1 CDS Amir_4743 NC_013093.1 5654448 5655251 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mmr:Mmar10_2631 ABC transporter; ABC transporter complement(5654448..5655251) Actinosynnema mirum DSM 43827 8328941 YP_003102419.1 CDS Amir_4744 NC_013093.1 5655401 5656192 R KEGG: mpo:Mpop_3497 integral membrane protein MviN; hypothetical protein complement(5655401..5656192) Actinosynnema mirum DSM 43827 8328942 YP_003102420.1 CDS Amir_4745 NC_013093.1 5656189 5656740 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: pla:Plav_1868 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit complement(5656189..5656740) Actinosynnema mirum DSM 43827 8328943 YP_003102421.1 CDS Amir_4746 NC_013093.1 5656977 5657804 R KEGG: rme:Rmet_3224 hypothetical protein; hypothetical protein complement(5656977..5657804) Actinosynnema mirum DSM 43827 8328944 YP_003102422.1 CDS Amir_4747 NC_013093.1 5657961 5659394 R PFAM: NAD(P) transhydrogenase beta subunit; KEGG: abo:ABO_1327 pyridine nucleotide transhydrogenase, B subunit; NAD(P)(+) transhydrogenase complement(5657961..5659394) Actinosynnema mirum DSM 43827 8328945 YP_003102423.1 CDS Amir_4748 NC_013093.1 5659391 5659765 R KEGG: afw:Anae109_2972 pyridine nucleotide transhydrogenase alpha subunit-like protein; NAD/NADP transhydrogenase alpha subunit-like protein complement(5659391..5659765) Actinosynnema mirum DSM 43827 8328946 YP_003102424.1 CDS Amir_4749 NC_013093.1 5659765 5660886 R PFAM: alanine dehydrogenase/PNT domain protein; KEGG: tgr:Tgr7_0268 NAD(P)(+) transhydrogenase (AB- specific); alanine dehydrogenase/PNT domain-containing protein complement(5659765..5660886) Actinosynnema mirum DSM 43827 8328947 YP_003102425.1 CDS Amir_4750 NC_013093.1 5661119 5661763 R PFAM: GCN5-related N-acetyltransferase; KEGG: sus:Acid_0202 hypothetical protein; GCN5-like N-acetyltransferase complement(5661119..5661763) Actinosynnema mirum DSM 43827 8328948 YP_003102426.1 CDS Amir_4751 NC_013093.1 5661779 5662504 R KEGG: bha:BH0230 hypothetical protein; hypothetical protein complement(5661779..5662504) Actinosynnema mirum DSM 43827 8328949 YP_003102427.1 CDS Amir_4752 NC_013093.1 5662504 5663871 R PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: oca:OCAR_7249 copper-containing nitrite reductase; nitrite reductase (NO-forming) complement(5662504..5663871) Actinosynnema mirum DSM 43827 8328950 YP_003102428.1 CDS Amir_4753 NC_013093.1 5663868 5665109 R KEGG: tbd:Tbd_2176 hypothetical protein; hypothetical protein complement(5663868..5665109) Actinosynnema mirum DSM 43827 8328951 YP_003102429.1 CDS Amir_4754 NC_013093.1 5665106 5666188 R KEGG: dar:Daro_3949 hypothetical protein; hypothetical protein complement(5665106..5666188) Actinosynnema mirum DSM 43827 8328952 YP_003102430.1 CDS Amir_4755 NC_013093.1 5666188 5666874 R KEGG: ank:AnaeK_1843 SpoIID/LytB domain protein; transcriptional regulator complement(5666188..5666874) Actinosynnema mirum DSM 43827 8328953 YP_003102431.1 CDS Amir_4756 NC_013093.1 5666935 5668914 R PFAM: peptidase M48 Ste24p; KEGG: acp:A2cp1_3025 peptidase M48 Ste24p; peptidase M48 Ste24p complement(5666935..5668914) Actinosynnema mirum DSM 43827 8328954 YP_003102432.1 CDS Amir_4757 NC_013093.1 5668904 5669356 R KEGG: pla:Plav_2920 ubiquinol-cytochrome C chaperone; ubiquinol-cytochrome C chaperone complement(5668904..5669356) Actinosynnema mirum DSM 43827 8328955 YP_003102433.1 CDS Amir_4758 NC_013093.1 5669632 5672106 D PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; KEGG: bba:Bd3234 carboxypeptidase T precursor; peptidase M14 carboxypeptidase A 5669632..5672106 Actinosynnema mirum DSM 43827 8328956 YP_003102434.1 CDS Amir_4759 NC_013093.1 5672231 5672353 R hypothetical protein complement(5672231..5672353) Actinosynnema mirum DSM 43827 8328957 YP_003102435.1 CDS Amir_4760 NC_013093.1 5672456 5672983 D SMART: calcium-binding EF-hand-containing protein; KEGG: Hypothetical protein CBG02402; calcium-binding EF-hand-containing protein 5672456..5672983 Actinosynnema mirum DSM 43827 8328958 YP_003102436.1 CDS Amir_4761 NC_013093.1 5672987 5673928 D TIGRFAM: methyltransferase; PFAM: O-methyltransferase; KEGG: bur:Bcep18194_B1573 protein of unknown function Mtu_121; methyltransferase 5672987..5673928 Actinosynnema mirum DSM 43827 8328959 YP_003102437.1 CDS Amir_4762 NC_013093.1 5674008 5674184 D KEGG: bvi:Bcep1808_5626 transposase, IS4 family protein; transposase, IS4 family protein 5674008..5674184 Actinosynnema mirum DSM 43827 8328960 YP_003102438.1 CDS Amir_4763 NC_013093.1 5674234 5674683 R PFAM: DoxX family protein; KEGG: scl:sce3628 hypothetical protein; DoxX family protein complement(5674234..5674683) Actinosynnema mirum DSM 43827 8328961 YP_003102439.1 CDS Amir_4764 NC_013093.1 5674880 5675425 D PFAM: regulatory protein TetR; KEGG: met:M446_2111 TetR family transcriptional regulator; TetR family transcriptional regulator 5674880..5675425 Actinosynnema mirum DSM 43827 8328962 YP_003102440.1 CDS Amir_4765 NC_013093.1 5675864 5679514 D KEGG: dar:Daro_3601 hypothetical protein; hypothetical protein 5675864..5679514 Actinosynnema mirum DSM 43827 8328963 YP_003102441.1 CDS Amir_4766 NC_013093.1 5679495 5680073 D hypothetical protein 5679495..5680073 Actinosynnema mirum DSM 43827 8328964 YP_003102442.1 CDS Amir_4768 NC_013093.1 5680797 5682326 D PFAM: periplasmic solute binding protein; KEGG: bra:BRADO6268 ABC transporter substrate- binding protein; periplasmic solute binding protein 5680797..5682326 Actinosynnema mirum DSM 43827 8328966 YP_003102443.1 CDS Amir_4769 NC_013093.1 5682314 5683150 D KEGG: GK21128 gene product from transcript GK21128- RA; hypothetical protein 5682314..5683150 Actinosynnema mirum DSM 43827 8328967 YP_003102444.1 CDS Amir_4770 NC_013093.1 5683143 5683895 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcz:pE33L54_0038 manganese ABC transporter, ATP-binding protein; ABC transporter 5683143..5683895 Actinosynnema mirum DSM 43827 8328968 YP_003102445.1 CDS Amir_4771 NC_013093.1 5683892 5684755 D PFAM: ABC transporter; KEGG: bha:BH1390 hypothetical protein; ABC transporter 5683892..5684755 Actinosynnema mirum DSM 43827 8328969 YP_003102446.1 CDS Amir_4772 NC_013093.1 5684723 5685838 R KEGG: pin:Ping_0445 colicin uptake-like protein; hypothetical protein complement(5684723..5685838) Actinosynnema mirum DSM 43827 8328970 YP_003102447.1 CDS Amir_4773 NC_013093.1 5685907 5687040 R PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: cko:CKO_00925 hypothetical protein; cobalamin synthesis protein P47K complement(5685907..5687040) Actinosynnema mirum DSM 43827 8328971 YP_003102448.1 CDS Amir_4774 NC_013093.1 5687063 5688067 R PFAM: protein of unknown function DUF916 cell surface KEGG: bcj:BCAM2172 patatin-like phospholipase; hypothetical protein complement(5687063..5688067) Actinosynnema mirum DSM 43827 8328972 YP_003102449.1 CDS Amir_4775 NC_013093.1 5688166 5689644 R KEGG: mno:Mnod_2545 hypothetical protein; hypothetical protein complement(5688166..5689644) Actinosynnema mirum DSM 43827 8328973 YP_003102450.1 CDS Amir_4776 NC_013093.1 5689751 5691541 R KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein complement(5689751..5691541) Actinosynnema mirum DSM 43827 8328974 YP_003102451.1 CDS Amir_4777 NC_013093.1 5691749 5692993 R PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE2035 membrane transport protein; major facilitator superfamily protein complement(5691749..5692993) Actinosynnema mirum DSM 43827 8328975 YP_003102452.1 CDS Amir_4778 NC_013093.1 5693219 5693950 D PFAM: methyltransferase small; KEGG: rpe:RPE_0637 methyltransferase small; methyltransferase small 5693219..5693950 Actinosynnema mirum DSM 43827 8328976 YP_003102453.1 CDS Amir_4779 NC_013093.1 5693947 5694759 D KEGG: pca:Pcar_1737 hypothetical protein; hypothetical protein 5693947..5694759 Actinosynnema mirum DSM 43827 8328977 YP_003102454.1 CDS Amir_4780 NC_013093.1 5694815 5695750 D PFAM: GHMP kinase; KEGG: mlo:mlr9540 hypothetical protein; GHMP kinase 5694815..5695750 Actinosynnema mirum DSM 43827 8328978 YP_003102455.1 CDS Amir_4781 NC_013093.1 5695829 5696833 D PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bpd:BURPS668_2001 cysteine synthase; pyridoxal-5'-phosphate-dependent protein beta subunit 5695829..5696833 Actinosynnema mirum DSM 43827 8328979 YP_003102456.1 CDS Amir_4782 NC_013093.1 5696891 5697874 R PFAM: periplasmic binding protein; KEGG: ABC transporter substrate binding protein (iron); K02016 iron complex transport system substrate-binding protein; periplasmic binding protein complement(5696891..5697874) Actinosynnema mirum DSM 43827 8328980 YP_003102457.1 CDS Amir_4783 NC_013093.1 5697871 5698662 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcj:BCAL1346 Fe uptake system ATP- binding protein; ABC transporter complement(5697871..5698662) Actinosynnema mirum DSM 43827 8328981 YP_003102458.1 CDS Amir_4784 NC_013093.1 5698659 5699720 R PFAM: transport system permease protein; KEGG: dac:Daci_3791 transport system permease protein; transport system permease complement(5698659..5699720) Actinosynnema mirum DSM 43827 8328982 YP_003102459.1 CDS Amir_4785 NC_013093.1 5699850 5700653 D PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: mca:MCA3003 UbiE/COQ5 family methlytransferase; type 11 methyltransferase 5699850..5700653 Actinosynnema mirum DSM 43827 8328983 YP_003102460.1 CDS Amir_4786 NC_013093.1 5700763 5701332 R PFAM: regulatory protein TetR; KEGG: rec:RHECIAT_CH0000638 probable transcriptional regulator protein, TetR family; TetR family transcriptional regulator complement(5700763..5701332) Actinosynnema mirum DSM 43827 8328984 YP_003102461.1 CDS Amir_4787 NC_013093.1 5701370 5702920 R PFAM: amidase; KEGG: bpt:Bpet1417 glutamyl-tRNA(Gln) amidotransferase subunit A; amidase complement(5701370..5702920) Actinosynnema mirum DSM 43827 8328985 YP_003102462.1 CDS Amir_4788 NC_013093.1 5703027 5703911 D PFAM: beta-lactamase domain protein; KEGG: rpt:Rpal_4911 beta-lactamase domain protein; beta-lactamase domain-containing protein 5703027..5703911 Actinosynnema mirum DSM 43827 8328986 YP_003102463.1 CDS Amir_4789 NC_013093.1 5704118 5705599 D PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5704118..5705599 Actinosynnema mirum DSM 43827 8328987 YP_003102464.1 CDS Amir_4790 NC_013093.1 5705681 5706631 R KEGG: reh:H16_A1489 DNA topoisomerase IB; DNA topoisomerase IB complement(5705681..5706631) Actinosynnema mirum DSM 43827 8328988 YP_003102465.1 CDS Amir_4791 NC_013093.1 5706727 5707599 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pag:PLES_56121 transcriptional regulator; LysR family transcriptional regulator complement(5706727..5707599) Actinosynnema mirum DSM 43827 8328989 YP_003102466.1 CDS Amir_4792 NC_013093.1 5707723 5708448 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sus:Acid_6073 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 5707723..5708448 Actinosynnema mirum DSM 43827 8328990 YP_003102467.1 CDS Amir_4793 NC_013093.1 5708448 5709302 D PFAM: amidohydrolase 2; KEGG: hypothetical protein; K07046; amidohydrolase 2 5708448..5709302 Actinosynnema mirum DSM 43827 8328991 YP_003102468.1 CDS Amir_4794 NC_013093.1 5709312 5709875 R PFAM: regulatory protein TetR; KEGG: ank:AnaeK_1572 regulatory protein TetR; TetR family transcriptional regulator complement(5709312..5709875) Actinosynnema mirum DSM 43827 8328992 YP_003102469.1 CDS Amir_4795 NC_013093.1 5709954 5710847 D PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: acp:A2cp1_1649 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 5709954..5710847 Actinosynnema mirum DSM 43827 8328993 YP_003102470.1 CDS Amir_4796 NC_013093.1 5710939 5712210 D PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: par:Psyc_1255 TolB periplamsic protein; hypothetical protein 5710939..5712210 Actinosynnema mirum DSM 43827 8328994 YP_003102471.1 CDS Amir_4798 NC_013093.1 5712680 5712907 D hypothetical protein 5712680..5712907 Actinosynnema mirum DSM 43827 8328996 YP_003102472.1 CDS Amir_4799 NC_013093.1 5712998 5714431 D PFAM: monooxygenase FAD-binding; KEGG: pde:Pden_3048 hypothetical protein; FAD-binding monooxygenase 5712998..5714431 Actinosynnema mirum DSM 43827 8328997 YP_003102473.1 CDS Amir_4800 NC_013093.1 5714472 5717240 R PFAM: transcriptional regulator domain protein; transcriptional activator domain; KEGG: afw:Anae109_3667 ATPase-like protein; transcriptional regulator, winged helix family complement(5714472..5717240) Actinosynnema mirum DSM 43827 8328998 YP_003102474.1 CDS Amir_4801 NC_013093.1 5717369 5718139 R PFAM: hypothetical protein; KEGG: gdi:GDI1794 hypothetical protein; hypothetical protein complement(5717369..5718139) Actinosynnema mirum DSM 43827 8328999 YP_003102475.1 CDS Amir_4802 NC_013093.1 5718169 5719695 R PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_1369 major facilitator superfamily MFS_1; major facilitator superfamily protein complement(5718169..5719695) Actinosynnema mirum DSM 43827 8329000 YP_003102476.1 CDS Amir_4803 NC_013093.1 5719816 5720397 D PFAM: regulatory protein TetR; KEGG: bac:BamMC406_5866 TetR family transcriptional regulator; TetR family transcriptional regulator 5719816..5720397 Actinosynnema mirum DSM 43827 8329001 YP_003102477.1 CDS Amir_4804 NC_013093.1 5720384 5720989 R PFAM: regulatory protein TetR; KEGG: sml:Smlt4073 TetR family regulatory protein; TetR family transcriptional regulator complement(5720384..5720989) Actinosynnema mirum DSM 43827 8329002 YP_003102478.1 CDS Amir_4805 NC_013093.1 5721051 5721557 R KEGG: afw:Anae109_0991 major facilitator transporter; hypothetical protein complement(5721051..5721557) Actinosynnema mirum DSM 43827 8329003 YP_003102479.1 CDS Amir_4806 NC_013093.1 5721662 5724019 R PFAM: coagulation factor 5/8 type domain protein; KEGG: hypothetical protein; coagulation factor 5/8 type domain-containing protein complement(5721662..5724019) Actinosynnema mirum DSM 43827 8329004 YP_003102480.1 CDS Amir_4807 NC_013093.1 5724121 5724600 R KEGG: mxa:MXAN_2741 hypothetical protein; hypothetical protein complement(5724121..5724600) Actinosynnema mirum DSM 43827 8329005 YP_003102481.1 CDS Amir_4808 NC_013093.1 5724696 5725592 R KEGG: swi:Swit_3769 NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerase-like protein complement(5724696..5725592) Actinosynnema mirum DSM 43827 8329006 YP_003102482.1 CDS Amir_4809 NC_013093.1 5725666 5726325 R PFAM: restriction endonuclease; KEGG: acr:Acry_3352 restriction endonuclease; restriction endonuclease complement(5725666..5726325) Actinosynnema mirum DSM 43827 8329007 YP_003102483.1 CDS Amir_4810 NC_013093.1 5726704 5726976 R hypothetical protein complement(5726704..5726976) Actinosynnema mirum DSM 43827 8329008 YP_003102484.1 CDS Amir_4811 NC_013093.1 5727628 5730831 D KEGG: pmy:Pmen_1048 signal transduction protein; signal transduction protein with Nacht domain 5727628..5730831 Actinosynnema mirum DSM 43827 8329009 YP_003102485.1 CDS Amir_4812 NC_013093.1 5731126 5732466 R KEGG: mlo:mll6125 cytochrome P450-family protein; cytochrome P450-family protein complement(5731126..5732466) Actinosynnema mirum DSM 43827 8329010 YP_003102486.1 CDS Amir_4813 NC_013093.1 5732463 5733071 R PFAM: protein of unknown function ATP binding; KEGG: dac:Daci_0776 protein of unknown function ATP binding; hypothetical protein complement(5732463..5733071) Actinosynnema mirum DSM 43827 8329011 YP_003102487.1 CDS Amir_4814 NC_013093.1 5733052 5733453 R PFAM: protein of unknown function DUF742; hypothetical protein complement(5733052..5733453) Actinosynnema mirum DSM 43827 8329012 YP_003102488.1 CDS Amir_4815 NC_013093.1 5733450 5733869 R PFAM: Roadblock/LC7 family protein; Roadblock/LC7 family protein complement(5733450..5733869) Actinosynnema mirum DSM 43827 8329013 YP_003102489.1 CDS Amir_4816 NC_013093.1 5734002 5735894 R PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: hypothetical protein; ATP-binding region ATPase domain-containing protein complement(5734002..5735894) Actinosynnema mirum DSM 43827 8329014 YP_003102490.1 CDS Amir_4817 NC_013093.1 5736441 5737106 D KEGG: ppw:PputW619_3130 hypothetical protein; hypothetical protein 5736441..5737106 Actinosynnema mirum DSM 43827 8329015 YP_003102491.1 CDS Amir_4818 NC_013093.1 5737156 5738241 R PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: atc:AGR_L_1778 hypothetical protein; oxidoreductase domain-containing protein complement(5737156..5738241) Actinosynnema mirum DSM 43827 8329016 YP_003102492.1 CDS Amir_4819 NC_013093.1 5738238 5738957 R PFAM: cupin; cupin complement(5738238..5738957) Actinosynnema mirum DSM 43827 8329017 YP_003102493.1 CDS Amir_4820 NC_013093.1 5738954 5739856 R KEGG: sus:Acid_2874 transmembrane prediction; hypothetical protein complement(5738954..5739856) Actinosynnema mirum DSM 43827 8329018 YP_003102494.1 CDS Amir_4821 NC_013093.1 5740013 5741146 D KEGG: spe:Spro_1142 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase; glycerate kinase 5740013..5741146 Actinosynnema mirum DSM 43827 8329019 YP_003102495.1 CDS Amir_4822 NC_013093.1 5741267 5742052 R PFAM: xylose isomerase; KEGG: hypothetical protein; xylose isomerase complement(5741267..5742052) Actinosynnema mirum DSM 43827 8329020 YP_003102496.1 CDS Amir_4823 NC_013093.1 5742161 5742889 D KEGG: ilo:IL1495 hypothetical protein; hypothetical protein 5742161..5742889 Actinosynnema mirum DSM 43827 8329021 YP_003102497.1 CDS Amir_4824 NC_013093.1 5742911 5743837 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pol:Bpro_4368 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(5742911..5743837) Actinosynnema mirum DSM 43827 8329022 YP_003102498.1 CDS Amir_4825 NC_013093.1 5743899 5745239 D PFAM: aminotransferase class-III; KEGG: bxe:Bxe_B2675 aminotransferase; class III aminotransferase 5743899..5745239 Actinosynnema mirum DSM 43827 8329023 YP_003102499.1 CDS Amir_4826 NC_013093.1 5745630 5746193 D KEGG: rsq:Rsph17025_0144 chromosome segregation protein SMC; hypothetical protein 5745630..5746193 Actinosynnema mirum DSM 43827 8329024 YP_003102500.1 CDS Amir_4827 NC_013093.1 5746691 5747029 R hypothetical protein complement(5746691..5747029) Actinosynnema mirum DSM 43827 8329025 YP_003102501.1 CDS Amir_4828 NC_013093.1 5747669 5749399 D PFAM: Ricin B lectin; SMART: Ricin B lectin; KEGG: bha:BH0494 exopolygalacturonate lyase; Ricin B lectin 5747669..5749399 Actinosynnema mirum DSM 43827 8329026 YP_003102502.1 CDS Amir_4829 NC_013093.1 5749479 5749982 R hypothetical protein complement(5749479..5749982) Actinosynnema mirum DSM 43827 8329027 YP_003102503.1 CDS Amir_4830 NC_013093.1 5750210 5750569 R KEGG: rfr:Rfer_3942 serine/threonine protein kinase with CHASE2 sensor; hypothetical protein complement(5750210..5750569) Actinosynnema mirum DSM 43827 8329028 YP_003102504.1 CDS Amir_4831 NC_013093.1 5750918 5751523 R KEGG: YALI0B22110p; hypothetical protein complement(5750918..5751523) Actinosynnema mirum DSM 43827 8329029 YP_003102505.1 CDS Amir_4832 NC_013093.1 5751527 5752615 R KEGG: hypothetical protein; hypothetical protein complement(5751527..5752615) Actinosynnema mirum DSM 43827 8329030 YP_003102506.1 CDS Amir_4833 NC_013093.1 5753248 5753793 R PFAM: protein of unknown function DUF1697; KEGG: cak:Caul_2927 hypothetical protein; hypothetical protein complement(5753248..5753793) Actinosynnema mirum DSM 43827 8329031 YP_003102507.1 CDS Amir_4834 NC_013093.1 5754258 5755592 D PFAM: cytochrome P450; KEGG: mxa:MXAN_2304 cytochrome P450 family protein; cytochrome P450 5754258..5755592 Actinosynnema mirum DSM 43827 8329032 YP_003102508.1 CDS Amir_4835 NC_013093.1 5755642 5757402 D KEGG: Eln; elastin; hypothetical protein 5755642..5757402 Actinosynnema mirum DSM 43827 8329033 YP_003102509.1 CDS Amir_4836 NC_013093.1 5757488 5758222 R PFAM: glycosyl transferase family 2; KEGG: gbm:Gbem_1276 glycosyl transferase family 2; family 2 glycosyl transferase complement(5757488..5758222) Actinosynnema mirum DSM 43827 8329034 YP_003102510.1 CDS Amir_4837 NC_013093.1 5758355 5758945 R PFAM: regulatory protein TetR; KEGG: msl:Msil_3313 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(5758355..5758945) Actinosynnema mirum DSM 43827 8329035 YP_003102511.1 CDS Amir_4838 NC_013093.1 5758972 5759886 R PFAM: NmrA family protein; KEGG: scl:sce0707 hypothetical protein; NmrA family protein complement(5758972..5759886) Actinosynnema mirum DSM 43827 8329036 YP_003102512.1 CDS Amir_4839 NC_013093.1 5760076 5760786 D KEGG: bcr:BCAH187_A3347 hypothetical protein; hypothetical protein 5760076..5760786 Actinosynnema mirum DSM 43827 8329037 YP_003102513.1 CDS Amir_4840 NC_013093.1 5760929 5761150 R hypothetical protein complement(5760929..5761150) Actinosynnema mirum DSM 43827 8329038 YP_003102514.1 CDS Amir_4841 NC_013093.1 5761240 5762571 R PFAM: glycosyl transferase family 28; KEGG: afw:Anae109_0485 glycosyl transferase family protein; Sterol 3-beta-glucosyltransferase complement(5761240..5762571) Actinosynnema mirum DSM 43827 8329039 YP_003102515.1 CDS Amir_4842 NC_013093.1 5762568 5764670 R PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: scl:sce8590 prolyl oligopeptidase; peptidase S9 prolyl oligopeptidase active site domain-containing protein complement(5762568..5764670) Actinosynnema mirum DSM 43827 8329040 YP_003102516.1 CDS Amir_4843 NC_013093.1 5764674 5765699 R PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; short- chain dehydrogenase/reductase SDR; KEGG: ppd:Ppro_3571 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(5764674..5765699) Actinosynnema mirum DSM 43827 8329041 YP_003102517.1 CDS Amir_4844 NC_013093.1 5765696 5767000 R PFAM: glycosyl transferase family 28; KEGG: afw:Anae109_0485 glycosyl transferase family protein; Sterol 3-beta-glucosyltransferase complement(5765696..5767000) Actinosynnema mirum DSM 43827 8329042 YP_003102518.1 CDS Amir_4845 NC_013093.1 5767060 5768277 R PFAM: cytochrome P450; KEGG: scl:sce8913 cytochrome P450 CYP109C2; cytochrome P450 complement(5767060..5768277) Actinosynnema mirum DSM 43827 8329043 YP_003102519.1 CDS Amir_4846 NC_013093.1 5768374 5768466 R hypothetical protein complement(5768374..5768466) Actinosynnema mirum DSM 43827 8329044 YP_003102520.1 CDS Amir_4847 NC_013093.1 5768520 5768618 R hypothetical protein complement(5768520..5768618) Actinosynnema mirum DSM 43827 8329045 YP_003102521.1 CDS Amir_4848 NC_013093.1 5768650 5771292 R PFAM: lanthionine synthetase C family protein; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; KEGG: smt:Smal_2130 serine/threonine protein kinase; serine/threonine protein kinase complement(5768650..5771292) Actinosynnema mirum DSM 43827 8329046 YP_003102522.1 CDS Amir_4849 NC_013093.1 5771450 5772061 R PFAM: flavoprotein; KEGG: tgr:Tgr7_0102 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; flavoprotein complement(5771450..5772061) Actinosynnema mirum DSM 43827 8329047 YP_003102523.1 CDS Amir_4850 NC_013093.1 5772058 5772672 R PFAM: MaoC domain protein dehydratase; KEGG: reu:Reut_A1571 MaoC-like dehydratase; MaoC domain-containing protein dehydratase complement(5772058..5772672) Actinosynnema mirum DSM 43827 8329048 YP_003102524.1 CDS Amir_4851 NC_013093.1 5772677 5773441 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(5772677..5773441) Actinosynnema mirum DSM 43827 8329049 YP_003102525.1 CDS Amir_4852 NC_013093.1 5773446 5774150 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: tbd:Tbd_1549 3-oxoacyl-[acyl-carrier-protein] reductase; short-chain dehydrogenase/reductase SDR complement(5773446..5774150) Actinosynnema mirum DSM 43827 8329050 YP_003102526.1 CDS Amir_4853 NC_013093.1 5774147 5779606 R PFAM: acyl transferase; beta-ketoacyl synthase; KR domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_4528 polyketide synthase; acyl transferase complement(5774147..5779606) Actinosynnema mirum DSM 43827 8329051 YP_003102527.1 CDS Amir_4855 NC_013093.1 5780990 5781487 D KEGG: gox:GOX1622 transposase; hypothetical protein 5780990..5781487 Actinosynnema mirum DSM 43827 8329053 YP_003102528.1 CDS Amir_4856 NC_013093.1 5781695 5783101 D PFAM: AMP-dependent synthetase and ligase; KEGG: bvi:Bcep1808_2651 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 5781695..5783101 Actinosynnema mirum DSM 43827 8329054 YP_003102529.1 CDS Amir_4857 NC_013093.1 5783098 5784357 D TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: beta-ketoacyl synthase; KEGG: mgm:Mmc1_1872 3-oxoacyl-[acyl-carrier- protein] synthase II; 3-oxoacyl-(acyl-carrier-protein) synthase 2 5783098..5784357 Actinosynnema mirum DSM 43827 8329055 YP_003102530.1 CDS Amir_4858 NC_013093.1 5784400 5785698 D PFAM: Aldehyde Dehydrogenase; KEGG: plu:plu3928 hypothetical protein; aldehyde dehydrogenase 5784400..5785698 Actinosynnema mirum DSM 43827 8329056 YP_003102531.1 CDS Amir_4859 NC_013093.1 5785695 5787365 D PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: eba:ebA4751 acetolactate synthase catalytic subunit; thiamine pyrophosphate protein 5785695..5787365 Actinosynnema mirum DSM 43827 8329057 YP_003102532.1 CDS Amir_4860 NC_013093.1 5787362 5789110 D PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce8262 non-ribosomal peptide synthetase; AMP-dependent synthetase and ligase 5787362..5789110 Actinosynnema mirum DSM 43827 8329058 YP_003102533.1 CDS Amir_4861 NC_013093.1 5789149 5789406 D PFAM: phosphopantetheine-binding; KEGG: pcr:Pcryo_0517 acyl carrier protein; phosphopantetheine-binding 5789149..5789406 Actinosynnema mirum DSM 43827 8329059 YP_003102534.1 CDS Amir_4862 NC_013093.1 5789471 5791270 R PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: bsu:BSU34820 hypothetical protein; ABC transporter complement(5789471..5791270) Actinosynnema mirum DSM 43827 8329060 YP_003102535.1 CDS Amir_4863 NC_013093.1 5791317 5791940 D PFAM: regulatory protein TetR; KEGG: bha:BH2103 hypothetical protein; TetR family transcriptional regulator 5791317..5791940 Actinosynnema mirum DSM 43827 8329061 YP_003102536.1 CDS Amir_4864 NC_013093.1 5791961 5794018 R TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bxe:Bxe_B1779 major facilitator superfamily multidrug efflux transporter; EmrB/QacA subfamily drug resistance transporter complement(5791961..5794018) Actinosynnema mirum DSM 43827 8329062 YP_003102537.1 CDS Amir_4865 NC_013093.1 5794273 5795706 R PFAM: major facilitator superfamily MFS_1; KEGG: bmv:BMASAVP1_0279 EmrB/QacA family drug resistance transporter; major facilitator superfamily protein complement(5794273..5795706) Actinosynnema mirum DSM 43827 8329063 YP_003102538.1 CDS Amir_4866 NC_013093.1 5795703 5797235 R PFAM: NHL repeat containing protein; KEGG: bxe:Bxe_C0275 hypothetical protein; NHL repeat containing protein complement(5795703..5797235) Actinosynnema mirum DSM 43827 8329064 YP_003102539.1 CDS Amir_4867 NC_013093.1 5797232 5799193 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pzu:PHZ_c1832 monooxygenase; cyclohexanone monooxygenase complement(5797232..5799193) Actinosynnema mirum DSM 43827 8329065 YP_003102540.1 CDS Amir_4868 NC_013093.1 5799287 5799661 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: kpe:KPK_1169 DNA-binding protein; XRE family transcriptional regulator 5799287..5799661 Actinosynnema mirum DSM 43827 8329066 YP_003102541.1 CDS Amir_4869 NC_013093.1 5799746 5806618 R TIGRFAM: YD repeat protein; SMART: Hedgehog/intein hint domain protein; KEGG: dal:Dalk_1487 YD repeat protein; YD repeat-containing protein complement(5799746..5806618) Actinosynnema mirum DSM 43827 8329067 YP_003102542.1 CDS Amir_4870 NC_013093.1 5806663 5810106 R SMART: LamG domain protein jellyroll fold domain protein; KEGG: bat:BAS1022 wall-associated protein; LamG domain-containing protein complement(5806663..5810106) Actinosynnema mirum DSM 43827 8329068 YP_003102543.1 CDS Amir_4871 NC_013093.1 5810478 5810864 R hypothetical protein complement(5810478..5810864) Actinosynnema mirum DSM 43827 8329069 YP_003102544.1 CDS Amir_4872 NC_013093.1 5810924 5813152 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: glycoside hydrolase, family 3, N- terminal:glycoside hydrolase, family 3, C-terminal; glycoside hydrolase family protein complement(5810924..5813152) Actinosynnema mirum DSM 43827 8329070 YP_003102545.1 CDS Amir_4873 NC_013093.1 5813249 5813830 D PFAM: regulatory protein TetR; KEGG: psb:Psyr_3154 regulatory protein, TetR; TetR family transcriptional regulator 5813249..5813830 Actinosynnema mirum DSM 43827 8329071 YP_003102546.1 CDS Amir_4874 NC_013093.1 5813832 5814254 R PFAM: GCN5-related N-acetyltransferase; KEGG: rlt:Rleg2_6394 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(5813832..5814254) Actinosynnema mirum DSM 43827 8329072 YP_003102547.1 CDS Amir_4875 NC_013093.1 5814319 5814594 R hypothetical protein complement(5814319..5814594) Actinosynnema mirum DSM 43827 8329073 YP_003102548.1 CDS Amir_4876 NC_013093.1 5814623 5814745 D hypothetical protein 5814623..5814745 Actinosynnema mirum DSM 43827 8329074 YP_003102549.1 CDS Amir_4877 NC_013093.1 5814878 5817448 D SMART: ATPase AAA; KEGG: mxa:MXAN_4188 adenylate/guanylate cyclase domain protein; ATPase AAA 5814878..5817448 Actinosynnema mirum DSM 43827 8329075 YP_003102550.1 CDS Amir_4878 NC_013093.1 5817461 5818051 R hypothetical protein complement(5817461..5818051) Actinosynnema mirum DSM 43827 8329076 YP_003102551.1 CDS Amir_4879 NC_013093.1 5818246 5819628 R KEGG: mxa:MXAN_2888 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Coproporphyrinogen dehydrogenase complement(5818246..5819628) Actinosynnema mirum DSM 43827 8329077 YP_003102552.1 CDS Amir_4880 NC_013093.1 5819649 5820002 R PFAM: NUDIX hydrolase; KEGG: mxa:MXAN_3769 hydrolase, NUDIX family; NUDIX hydrolase complement(5819649..5820002) Actinosynnema mirum DSM 43827 8329078 YP_003102553.1 CDS Amir_4881 NC_013093.1 5820276 5820926 D KEGG: pla:Plav_1718 shikimate kinase; hypothetical protein 5820276..5820926 Actinosynnema mirum DSM 43827 8329079 YP_003102554.1 CDS Amir_4882 NC_013093.1 5821126 5822457 D PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: dal:Dalk_4445 peptidase M20; hypothetical protein 5821126..5822457 Actinosynnema mirum DSM 43827 8329080 YP_003102555.1 CDS Amir_4883 NC_013093.1 5822599 5823291 D hypothetical protein 5822599..5823291 Actinosynnema mirum DSM 43827 8329081 YP_003102556.1 CDS Amir_4884 NC_013093.1 5823448 5824230 R PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: sus:Acid_3105 IclR family transcriptional regulator; IclR family transcriptional regulator complement(5823448..5824230) Actinosynnema mirum DSM 43827 8329082 YP_003102557.1 CDS Amir_4885 NC_013093.1 5824290 5825072 R PFAM: purine or other phosphorylase family 1; KEGG: aha:AHA_3168 uridine phosphorylase; purine or other phosphorylase family 1 complement(5824290..5825072) Actinosynnema mirum DSM 43827 8329083 YP_003102558.1 CDS Amir_4886 NC_013093.1 5825271 5826164 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sat:SYN_00367 sulfate transport ATP-binding protein; ABC transporter 5825271..5826164 Actinosynnema mirum DSM 43827 8329084 YP_003102559.1 CDS Amir_4887 NC_013093.1 5826161 5826964 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bav:BAV0644 ABC transporter, permease protein; ABC transporter inner membrane protein 5826161..5826964 Actinosynnema mirum DSM 43827 8329085 YP_003102560.1 CDS Amir_4888 NC_013093.1 5827032 5828063 D PFAM: NMT1/THI5 like domain protein; SMART: extracellular solute-binding protein family 3; KEGG: mes:Meso_0815 sulfonate transport system substrate-binding protein; NMT1/THI5 like domain-containing protein 5827032..5828063 Actinosynnema mirum DSM 43827 8329086 YP_003102561.1 CDS Amir_4889 NC_013093.1 5828060 5828836 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_1169 ABC transporter permease protein; ABC transporter inner membrane protein 5828060..5828836 Actinosynnema mirum DSM 43827 8329087 YP_003102562.1 CDS Amir_4890 NC_013093.1 5829168 5829638 D KEGG: type I polyketide synthase; K09936 hypothetical protein; type I polyketide synthase 5829168..5829638 Actinosynnema mirum DSM 43827 8329088 YP_003102563.1 CDS Amir_4891 NC_013093.1 5829982 5831325 D TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: scl:sce4269 dihydroorotase; dihydroorotase, multifunctional complex type 5829982..5831325 Actinosynnema mirum DSM 43827 8329089 YP_003102564.1 CDS Amir_4892 NC_013093.1 5831395 5832351 R PFAM: Kelch repeat-containing protein; Kelch repeat protein; SMART: Kelch repeat-containing protein; KEGG: mex:Mext_0574 kelch repeat-containing protein; Kelch repeat-containing protein complement(5831395..5832351) Actinosynnema mirum DSM 43827 8329090 YP_003102565.1 CDS Amir_4893 NC_013093.1 5832435 5833277 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; LysR family transcriptional regulator 5832435..5833277 Actinosynnema mirum DSM 43827 8329091 YP_003102566.1 CDS Amir_4894 NC_013093.1 5833474 5835150 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: scl:sce5237 protein kinase; serine/threonine protein kinase 5833474..5835150 Actinosynnema mirum DSM 43827 8329092 YP_003102567.1 CDS Amir_4895 NC_013093.1 5835680 5835904 D hypothetical protein 5835680..5835904 Actinosynnema mirum DSM 43827 8329093 YP_003102568.1 CDS Amir_4896 NC_013093.1 5836268 5837341 R PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bam:Bamb_4722 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase complement(5836268..5837341) Actinosynnema mirum DSM 43827 8329094 YP_003102569.1 CDS Amir_4897 NC_013093.1 5837497 5837952 D PFAM: regulatory protein MarR; regulatory protein ArsR; SMART: regulatory protein MarR; KEGG: azc:AZC_0116 regulatory protein; MarR family transcriptional regulator 5837497..5837952 Actinosynnema mirum DSM 43827 8329095 YP_003102570.1 CDS Amir_4898 NC_013093.1 5838111 5838470 D KEGG: bsu:BSU26920 hypothetical protein; hypothetical protein 5838111..5838470 Actinosynnema mirum DSM 43827 8329096 YP_003102571.1 CDS Amir_4899 NC_013093.1 5838516 5838890 R hypothetical protein complement(5838516..5838890) Actinosynnema mirum DSM 43827 8329097 YP_003102572.1 CDS Amir_4900 NC_013093.1 5839320 5839988 D KEGG: bce:BC3289 hypothetical protein; hypothetical protein 5839320..5839988 Actinosynnema mirum DSM 43827 8329098 YP_003102573.1 CDS Amir_4901 NC_013093.1 5840182 5840667 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: reu:Reut_A1539 LuxR family transcriptional regulator; LuxR family transcriptional regulator 5840182..5840667 Actinosynnema mirum DSM 43827 8329099 YP_003102574.1 CDS Amir_4902 NC_013093.1 5840759 5841199 R hypothetical protein complement(5840759..5841199) Actinosynnema mirum DSM 43827 8329100 YP_003102575.1 CDS Amir_4903 NC_013093.1 5841304 5842035 R PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: jan:Jann_4133 GntR family transcriptional regulator; GntR family transcriptional regulator complement(5841304..5842035) Actinosynnema mirum DSM 43827 8329101 YP_003102576.1 CDS Amir_4904 NC_013093.1 5842070 5842849 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: rsq:Rsph17025_3334 hypothetical protein; ABC transporter complement(5842070..5842849) Actinosynnema mirum DSM 43827 8329102 YP_003102577.1 CDS Amir_4905 NC_013093.1 5842846 5843895 R PFAM: transport system permease protein; KEGG: dac:Daci_3152 transport system permease protein; transport system permease complement(5842846..5843895) Actinosynnema mirum DSM 43827 8329103 YP_003102578.1 CDS Amir_4906 NC_013093.1 5843892 5844974 R PFAM: transport system permease protein; KEGG: atc:AGR_pAT_449 ferric enterobactin transport protein FepD; transport system permease complement(5843892..5844974) Actinosynnema mirum DSM 43827 8329104 YP_003102579.1 CDS Amir_4907 NC_013093.1 5844974 5845930 R PFAM: periplasmic binding protein; KEGG: bsu:BSU08440 hypothetical protein; periplasmic binding protein complement(5844974..5845930) Actinosynnema mirum DSM 43827 8329105 YP_003102580.1 CDS Amir_4908 NC_013093.1 5846003 5847709 R KEGG: mxa:MXAN_2857 lantibiotic modification protein; lantibiotic modification protein complement(5846003..5847709) Actinosynnema mirum DSM 43827 8329106 YP_003102581.1 CDS Amir_4909 NC_013093.1 5847706 5848596 R PFAM: aminotransferase class IV; KEGG: afw:Anae109_1102 branched-chain amino acid aminotransferase; class IV aminotransferase complement(5847706..5848596) Actinosynnema mirum DSM 43827 8329107 YP_003102582.1 CDS Amir_4910 NC_013093.1 5848593 5849711 R PFAM: luciferase-like monooxygenase; KEGG: mxa:MXAN_4001 non-ribosomal peptide synthase/polyketide synthase; luciferase-like monooxygenase complement(5848593..5849711) Actinosynnema mirum DSM 43827 8329108 YP_003102583.1 CDS Amir_4911 NC_013093.1 5849711 5854111 R PFAM: beta-ketoacyl synthase; KR domain protein; acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3620 polyketide synthase type I; beta-ketoacyl synthase complement(5849711..5854111) Actinosynnema mirum DSM 43827 8329109 YP_003102584.1 CDS Amir_4912 NC_013093.1 5854108 5859255 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase; amino acid adenylation domain-containing protein complement(5854108..5859255) Actinosynnema mirum DSM 43827 8329110 YP_003102585.1 CDS Amir_4913 NC_013093.1 5859252 5861474 R PFAM: peptidase S45 penicillin amidase; KEGG: scl:sce8259 penicillin amidase; peptidase S45 penicillin amidase complement(5859252..5861474) Actinosynnema mirum DSM 43827 8329111 YP_003102586.1 CDS Amir_4914 NC_013093.1 5861467 5862804 R PFAM: condensation domain protein; KEGG: mxa:MXAN_4525 non-ribosomal peptide synthase MxaA; condensation domain-containing protein complement(5861467..5862804) Actinosynnema mirum DSM 43827 8329112 YP_003102587.1 CDS Amir_4915 NC_013093.1 5862801 5863847 R PFAM: aldo/keto reductase; KEGG: hypothetical protein; aldo/keto reductase complement(5862801..5863847) Actinosynnema mirum DSM 43827 8329113 YP_003102588.1 CDS Amir_4916 NC_013093.1 5863840 5865111 R PFAM: major facilitator superfamily MFS_1; KEGG: bpy:Bphyt_3134 major facilitator superfamily MFS_1; major facilitator superfamily protein complement(5863840..5865111) Actinosynnema mirum DSM 43827 8329114 YP_003102589.1 CDS Amir_4917 NC_013093.1 5865169 5865267 R hypothetical protein complement(5865169..5865267) Actinosynnema mirum DSM 43827 8329115 YP_003102590.1 CDS Amir_4918 NC_013093.1 5865719 5866492 D PFAM: thiazole biosynthesis family protein; KEGG: esa:ESA_03683 thiazole synthase; thiazole biosynthesis family protein 5865719..5866492 Actinosynnema mirum DSM 43827 8329116 YP_003102591.1 CDS Amir_4919 NC_013093.1 5866938 5867300 R PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist complement(5866938..5867300) Actinosynnema mirum DSM 43827 8329117 YP_003102592.1 CDS Amir_4920 NC_013093.1 5867297 5868397 R PFAM: cobalamin B12-binding domain protein; KEGG: rpc:RPC_1467 cobalamin B12-binding; cobalamin B12-binding domain-containing protein complement(5867297..5868397) Actinosynnema mirum DSM 43827 8329118 YP_003102593.1 CDS Amir_4921 NC_013093.1 5868394 5870043 R PFAM: Stage II sporulation E family protein; GAF domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; KEGG: sus:Acid_6601 serine phosphatase; protein serine phosphatase with GAF(s) sensor(s) complement(5868394..5870043) Actinosynnema mirum DSM 43827 8329119 YP_003102594.1 CDS Amir_4922 NC_013093.1 5870336 5870731 R KEGG: rsq:Rsph17025_3833 hypothetical protein; hypothetical protein complement(5870336..5870731) Actinosynnema mirum DSM 43827 8329120 YP_003102595.1 CDS Amir_4923 NC_013093.1 5870927 5871964 R KEGG: nar:Saro_3082 protein tyrosine/serine phosphatase; protein tyrosine/serine phosphatase complement(5870927..5871964) Actinosynnema mirum DSM 43827 8329121 YP_003102596.1 CDS Amir_4924 NC_013093.1 5871973 5873988 R KEGG: mxa:MXAN_6381 hypothetical protein; hypothetical protein complement(5871973..5873988) Actinosynnema mirum DSM 43827 8329122 YP_003102597.1 CDS Amir_4925 NC_013093.1 5873990 5874877 R KEGG: nar:Saro_1805 hypothetical protein; hypothetical protein complement(5873990..5874877) Actinosynnema mirum DSM 43827 8329123 YP_003102598.1 CDS Amir_4926 NC_013093.1 5875296 5876483 D KEGG: bxe:Bxe_B2117 CdaR family transcriptional regulator; CdaR family transcriptional regulator 5875296..5876483 Actinosynnema mirum DSM 43827 8329124 YP_003102599.1 CDS Amir_4927 NC_013093.1 5876641 5878128 D PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1549 ABC transporter substrate-binding protein; family 5 extracellular solute-binding protein 5876641..5878128 Actinosynnema mirum DSM 43827 8329125 YP_003102600.1 CDS Amir_4928 NC_013093.1 5878163 5879878 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_2742 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 5878163..5879878 Actinosynnema mirum DSM 43827 8329126 YP_003102601.1 CDS Amir_4929 NC_013093.1 5879879 5881066 D PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_3208 major facilitator transporter; major facilitator superfamily protein 5879879..5881066 Actinosynnema mirum DSM 43827 8329127 YP_003102602.1 CDS Amir_4930 NC_013093.1 5881105 5882268 R SMART: helix-turn-helix domain protein; KEGG: bvi:Bcep1808_6371 transcriptional regulator; helix-turn-helix domain-containing protein complement(5881105..5882268) Actinosynnema mirum DSM 43827 8329128 YP_003102603.1 CDS Amir_4931 NC_013093.1 5882507 5883967 D PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: pde:Pden_4560 sodium/sulphate symporter; sodium/sulfate symporter 5882507..5883967 Actinosynnema mirum DSM 43827 8329129 YP_003102604.1 CDS Amir_4932 NC_013093.1 5883986 5885137 D KEGG: pde:Pden_4561 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase; glycerate kinase 5883986..5885137 Actinosynnema mirum DSM 43827 8329130 YP_003102605.1 CDS Amir_4933 NC_013093.1 5885217 5885537 D KEGG: scl:sce2447 transcriptional regulator; transcriptional regulator 5885217..5885537 Actinosynnema mirum DSM 43827 8329131 YP_003102606.1 CDS Amir_4934 NC_013093.1 5885573 5887120 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase 5885573..5887120 Actinosynnema mirum DSM 43827 8329132 YP_003102607.1 CDS Amir_4935 NC_013093.1 5887105 5887770 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: two component heavy metal response transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 5887105..5887770 Actinosynnema mirum DSM 43827 8329133 YP_003102608.1 CDS Amir_4936 NC_013093.1 5888249 5889085 D PFAM: lytic transglycosylase catalytic; KEGG: bsu:BSU26030 hypothetical protein; lytic transglycosylase 5888249..5889085 Actinosynnema mirum DSM 43827 8329134 YP_003102609.1 CDS Amir_4937 NC_013093.1 5889386 5890978 D TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: rpe:RPE_0181 Na+/H+ antiporter; Na+/H+ antiporter 5889386..5890978 Actinosynnema mirum DSM 43827 8329135 YP_003102610.1 CDS Amir_4938 NC_013093.1 5890985 5892421 R PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_1465 major facilitator transporter; major facilitator superfamily protein complement(5890985..5892421) Actinosynnema mirum DSM 43827 8329136 YP_003102611.1 CDS Amir_4939 NC_013093.1 5892418 5893296 R PFAM: alpha/beta hydrolase fold; KEGG: bvi:Bcep1808_3804 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein complement(5892418..5893296) Actinosynnema mirum DSM 43827 8329137 YP_003102612.1 CDS Amir_4940 NC_013093.1 5893330 5894262 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; LysR family transcriptional regulator 5893330..5894262 Actinosynnema mirum DSM 43827 8329138 YP_003102613.1 CDS Amir_4941 NC_013093.1 5894326 5894721 D hypothetical protein 5894326..5894721 Actinosynnema mirum DSM 43827 8329139 YP_003102614.1 CDS Amir_4942 NC_013093.1 5894806 5895813 D PFAM: short-chain dehydrogenase/reductase SDR; NAD- dependent epimerase/dehydratase; KEGG: short-chain dehydrogenase/reductase (SDR) family protein; short-chain dehydrogenase/reductase SDR 5894806..5895813 Actinosynnema mirum DSM 43827 8329140 YP_003102615.1 CDS Amir_4943 NC_013093.1 5895901 5896632 R PFAM: survival protein SurE; KEGG: rce:RC1_0808 5'/3'-nucleotidase SurE; survival protein SurE complement(5895901..5896632) Actinosynnema mirum DSM 43827 8329141 YP_003102616.1 CDS Amir_4944 NC_013093.1 5896629 5897543 R PFAM: PfkB domain protein; KEGG: bha:BH0827 fructose 1-phosphate kinase; PfkB domain-containing protein complement(5896629..5897543) Actinosynnema mirum DSM 43827 8329142 YP_003102617.1 CDS Amir_4945 NC_013093.1 5897661 5899031 R KEGG: scl:sce9313 hypothetical protein; hypothetical protein complement(5897661..5899031) Actinosynnema mirum DSM 43827 8329143 YP_003102618.1 CDS Amir_4946 NC_013093.1 5899252 5900142 D KEGG: hypothetical protein; hypothetical protein 5899252..5900142 Actinosynnema mirum DSM 43827 8329144 YP_003102619.1 CDS Amir_4947 NC_013093.1 5900186 5901841 R PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: hypothetical protein; amine oxidase complement(5900186..5901841) Actinosynnema mirum DSM 43827 8329145 YP_003102620.1 CDS Amir_4948 NC_013093.1 5901951 5902766 D KEGG: bid:Bind_2275 membrane protein-like protein; hypothetical protein 5901951..5902766 Actinosynnema mirum DSM 43827 8329146 YP_003102621.1 CDS Amir_4949 NC_013093.1 5902763 5903920 D PFAM: glycosyl transferase family 2; KEGG: mex:Mext_3434 glycosyl transferase family protein; family 2 glycosyl transferase 5902763..5903920 Actinosynnema mirum DSM 43827 8329147 YP_003102622.1 CDS Amir_4950 NC_013093.1 5903864 5904598 R PFAM: CDP-alcohol phosphatidyltransferase; KEGG: ank:AnaeK_2943 CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase complement(5903864..5904598) Actinosynnema mirum DSM 43827 8329148 YP_003102623.1 CDS Amir_4951 NC_013093.1 5905661 5906506 D KEGG: dsh:Dshi_1005 ribonuclease BN; hypothetical protein 5905661..5906506 Actinosynnema mirum DSM 43827 8329149 YP_003102624.1 CDS Amir_4952 NC_013093.1 5906591 5907799 D KEGG: mxa:MXAN_1566 hypothetical protein; hypothetical protein 5906591..5907799 Actinosynnema mirum DSM 43827 8329150 YP_003102625.1 CDS Amir_4953 NC_013093.1 5908004 5908942 D PFAM: peptidase M28; peptidase M20; KEGG: pap:PSPA7_2223 aminopeptidase; aminopeptidase 5908004..5908942 Actinosynnema mirum DSM 43827 8329151 YP_003102626.1 CDS Amir_4954 NC_013093.1 5908946 5909863 R PFAM: protein of unknown function DUF6 transmembrane; KEGG: psb:Psyr_1799 hypothetical protein; hypothetical protein complement(5908946..5909863) Actinosynnema mirum DSM 43827 8329152 YP_003102627.1 CDS Amir_4955 NC_013093.1 5909924 5910580 D PFAM: regulatory protein TetR; KEGG: bxe:Bxe_B3018 TetR family transcriptional regulator; TetR family transcriptional regulator 5909924..5910580 Actinosynnema mirum DSM 43827 8329153 YP_003102628.1 CDS Amir_4956 NC_013093.1 5910899 5911636 D PFAM: glycosyl transferase family 2; KEGG: aba:Acid345_0505 glycosyl transferase, family 2; family 2 glycosyl transferase 5910899..5911636 Actinosynnema mirum DSM 43827 8329154 YP_003102629.1 CDS Amir_4957 NC_013093.1 5911633 5913189 D PFAM: glycosyl transferase group 1; KEGG: afw:Anae109_1425 glycosyl transferase group 1; group 1 glycosyl transferase 5911633..5913189 Actinosynnema mirum DSM 43827 8329155 YP_003102630.1 CDS Amir_4958 NC_013093.1 5913243 5915711 D PFAM: glycosyl transferase group 1; KEGG: ade:Adeh_3504 phosphatidylinositol alpha- mannosyltransferase; group 1 glycosyl transferase 5913243..5915711 Actinosynnema mirum DSM 43827 8329156 YP_003102631.1 CDS Amir_4959 NC_013093.1 5915708 5917198 D KEGG: tgr:Tgr7_3096 glycosyl transferase family 39; hypothetical protein 5915708..5917198 Actinosynnema mirum DSM 43827 8329157 YP_003102632.1 CDS Amir_4960 NC_013093.1 5917195 5918349 D PFAM: acyltransferase 3; KEGG: cak:Caul_2329 acyltransferase 3; acyltransferase 3 5917195..5918349 Actinosynnema mirum DSM 43827 8329158 YP_003102633.1 CDS Amir_4961 NC_013093.1 5918378 5919166 R KEGG: dal:Dalk_1860 hypothetical protein; hypothetical protein complement(5918378..5919166) Actinosynnema mirum DSM 43827 8329159 YP_003102634.1 CDS Amir_4962 NC_013093.1 5919163 5919753 R PFAM: regulatory protein TetR; KEGG: rme:Rmet_4903 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(5919163..5919753) Actinosynnema mirum DSM 43827 8329160 YP_003102635.1 CDS Amir_4963 NC_013093.1 5919904 5922537 R PFAM: glycoside hydrolase family 3 domain protein; KEGG: rfr:Rfer_1113 glycoside hydrolase family protein; glycoside hydrolase family protein complement(5919904..5922537) Actinosynnema mirum DSM 43827 8329161 YP_003102636.1 CDS Amir_4964 NC_013093.1 5922777 5925161 R PFAM: pectinesterase; Ricin B lectin; pectate lyase/Amb allergen; SMART: Ricin B lectin; Parallel beta-helix repeat; pectate lyase/Amb allergen; KEGG: bha:BH0698 pectate lyase; pectinesterase complement(5922777..5925161) Actinosynnema mirum DSM 43827 8329162 YP_003102637.1 CDS Amir_4965 NC_013093.1 5925378 5926304 D KEGG: pip; proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; proline iminopeptidase 5925378..5926304 Actinosynnema mirum DSM 43827 8329163 YP_003102638.1 CDS Amir_4966 NC_013093.1 5926380 5927903 R KEGG: hypothetical protein; PFAM: glycoside hydrolase family 62; Ricin B lectin; SMART: Ricin B lectin; alpha-N-arabinofuranosidase complement(5926380..5927903) Actinosynnema mirum DSM 43827 8329164 YP_003102639.1 CDS Amir_4967 NC_013093.1 5928141 5928362 R hypothetical protein complement(5928141..5928362) Actinosynnema mirum DSM 43827 8329165 YP_003102640.1 CDS Amir_4968 NC_013093.1 5928359 5928478 R hypothetical protein complement(5928359..5928478) Actinosynnema mirum DSM 43827 8329166 YP_003102641.1 CDS Amir_4969 NC_013093.1 5928734 5929717 D KEGG: acr:Acry_0972 methionyl-tRNA synthetase; methionyl-tRNA synthetase-like protein 5928734..5929717 Actinosynnema mirum DSM 43827 8329167 YP_003102642.1 CDS Amir_4970 NC_013093.1 5929742 5930332 R PFAM: methyltransferase type 12; methyltransferase type 11; Tellurite resistance methyltransferase, TehB, core; thiopurine S-methyltransferase; KEGG: scl:sce2146 methyltransferase; type 12 methyltransferase complement(5929742..5930332) Actinosynnema mirum DSM 43827 8329168 YP_003102643.1 CDS Amir_4971 NC_013093.1 5930579 5931733 D PFAM: monooxygenase FAD-binding; KEGG: bur:Bcep18194_A4891 monooxygenase, FAD- binding; FAD-binding monooxygenase 5930579..5931733 Actinosynnema mirum DSM 43827 8329169 YP_003102644.1 CDS Amir_4974 NC_013093.1 5933060 5934679 D KEGG: MYH3; myosin, heavy chain 3, skeletal muscle, embryonic; K10352 myosin heavy chain; hypothetical protein 5933060..5934679 Actinosynnema mirum DSM 43827 8329172 YP_003102645.1 CDS Amir_4975 NC_013093.1 5934962 5937010 R PFAM: MMPL domain protein; KEGG: bcz:BCZK2163 MmpL family integral membrane protein; MMPL domain-containing protein complement(5934962..5937010) Actinosynnema mirum DSM 43827 8329173 YP_003102646.1 CDS Amir_4976 NC_013093.1 5937089 5937553 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: cak:Caul_0809 MarR family transcriptional regulator; MarR family transcriptional regulator 5937089..5937553 Actinosynnema mirum DSM 43827 8329174 YP_003102647.1 CDS Amir_4977 NC_013093.1 5937606 5938742 D TIGRFAM: glycosyltransferase, MGT family; PFAM: protein of unknown function DUF1205; KEGG: bsu:BSU12220 hypothetical protein; MGT family glycosyltransferase 5937606..5938742 Actinosynnema mirum DSM 43827 8329175 YP_003102648.1 CDS Amir_4978 NC_013093.1 5939063 5940232 D TIGRFAM: glycosyltransferase, MGT family; PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; KEGG: ecf:ECH74115_1369 glycosyl transferase; MGT family glycosyltransferase 5939063..5940232 Actinosynnema mirum DSM 43827 8329176 YP_003102649.1 CDS Amir_4979 NC_013093.1 5940308 5941630 R PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: scl:sce2495 hemolysin; hypothetical protein complement(5940308..5941630) Actinosynnema mirum DSM 43827 8329177 YP_003102650.1 CDS Amir_4980 NC_013093.1 5941747 5942130 D hypothetical protein 5941747..5942130 Actinosynnema mirum DSM 43827 8329178 YP_003102651.1 CDS Amir_4981 NC_013093.1 5942123 5942653 D KEGG: GA24328 gene product from transcript GA24328- RA; hypothetical protein 5942123..5942653 Actinosynnema mirum DSM 43827 8329179 YP_003102652.1 CDS Amir_4982 NC_013093.1 5942646 5942987 D KEGG: hne:HNE_2114 hypothetical protein; hypothetical protein 5942646..5942987 Actinosynnema mirum DSM 43827 8329180 YP_003102653.1 CDS Amir_4983 NC_013093.1 5942988 5943158 R hypothetical protein complement(5942988..5943158) Actinosynnema mirum DSM 43827 8329181 YP_003102654.1 CDS Amir_4984 NC_013093.1 5943412 5945070 D KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein 5943412..5945070 Actinosynnema mirum DSM 43827 8329182 YP_003102655.1 CDS Amir_4985 NC_013093.1 5945067 5947130 R PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce5225 protein kinase; hypothetical protein complement(5945067..5947130) Actinosynnema mirum DSM 43827 8329183 YP_003102656.1 CDS Amir_4986 NC_013093.1 5947208 5947435 R PFAM: protein of unknown function DUF397; hypothetical protein complement(5947208..5947435) Actinosynnema mirum DSM 43827 8329184 YP_003102657.1 CDS Amir_4987 NC_013093.1 5947724 5948581 R SMART: helix-turn-helix domain protein; XRE family transcriptional regulator complement(5947724..5948581) Actinosynnema mirum DSM 43827 8329185 YP_003102658.1 CDS Amir_4988 NC_013093.1 5949273 5949842 D KEGG: bra:BRADO4970 hypothetical protein; hypothetical protein 5949273..5949842 Actinosynnema mirum DSM 43827 8329186 YP_003102659.1 CDS Amir_4989 NC_013093.1 5949889 5950326 R hypothetical protein complement(5949889..5950326) Actinosynnema mirum DSM 43827 8329187 YP_003102660.1 CDS Amir_4990 NC_013093.1 5950479 5951099 D TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: nmc:NMC1726 hypothetical protein; Sua5/YciO/YrdC/YwlC family protein 5950479..5951099 Actinosynnema mirum DSM 43827 8329188 YP_003102661.1 CDS Amir_4991 NC_013093.1 5951198 5951728 D KEGG: hypothetical protein; hypothetical protein 5951198..5951728 Actinosynnema mirum DSM 43827 8329189 YP_003102662.1 CDS Amir_4992 NC_013093.1 5951838 5952440 D PFAM: hypothetical protein; KEGG: mch:Mchl_4966 hypothetical protein; hypothetical protein 5951838..5952440 Actinosynnema mirum DSM 43827 8329190 YP_003102663.1 CDS Amir_4993 NC_013093.1 5952533 5953585 D hypothetical protein 5952533..5953585 Actinosynnema mirum DSM 43827 8329191 YP_003102664.1 CDS Amir_4994 NC_013093.1 5953663 5954361 R KEGG: esa:ESA_01086 hypothetical protein; hypothetical protein complement(5953663..5954361) Actinosynnema mirum DSM 43827 8329192 YP_003102665.1 CDS Amir_4995 NC_013093.1 5954405 5955061 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(5954405..5955061) Actinosynnema mirum DSM 43827 8329193 YP_003102666.1 CDS Amir_4996 NC_013093.1 5955058 5956275 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: mch:Mchl_4713 histidine kinase; histidine kinase complement(5955058..5956275) Actinosynnema mirum DSM 43827 8329194 YP_003102667.1 CDS Amir_4997 NC_013093.1 5956415 5957347 D KEGG: bte:BTH_II2362 esterase EstC; hypothetical protein 5956415..5957347 Actinosynnema mirum DSM 43827 8329195 YP_003102668.1 CDS Amir_4999 NC_013093.1 5957860 5958462 R KEGG: HDA1511; class II RPD3 type histone deacetylase protein; K11407 histone deacetylase 6/10; histone deacetylase complement(5957860..5958462) Actinosynnema mirum DSM 43827 8329197 YP_003102669.1 CDS Amir_5000 NC_013093.1 5958438 5958995 R PFAM: GCN5-related N-acetyltransferase; KEGG: pla:Plav_1643 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase complement(5958438..5958995) Actinosynnema mirum DSM 43827 8329198 YP_003102670.1 CDS Amir_5001 NC_013093.1 5959005 5960336 R PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bpt:Bpet3509 branched-chain alpha-keto acid dehydrogenase subunit E2; branched-chain alpha-keto acid dehydrogenase subunit E2 complement(5959005..5960336) Actinosynnema mirum DSM 43827 8329199 YP_003102671.1 CDS Amir_5002 NC_013093.1 5960329 5961306 R PFAM: transketolase; transketolase; KEGG: nha:Nham_3108 transketolase, central region; transketolase complement(5960329..5961306) Actinosynnema mirum DSM 43827 8329200 YP_003102672.1 CDS Amir_5003 NC_013093.1 5961381 5962493 R KEGG: ank:AnaeK_1422 pyruvate dehydrogenase (acetyl- transferring); TIGRFAM: pyruvate dehydrogenase (acetyl- transferring) E1 component, alpha subunit; PFAM: dehydrogenase E1 component; pyruvate dehydrogenase E1 component subunit alpha complement(5961381..5962493) Actinosynnema mirum DSM 43827 8329201 YP_003102673.1 CDS Amir_5004 NC_013093.1 5962605 5963093 D PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: har:HEAR0121 leucine-responsive regulatory protein; AsnC family transcriptional regulator 5962605..5963093 Actinosynnema mirum DSM 43827 8329202 YP_003102674.1 CDS Amir_5005 NC_013093.1 5963435 5964199 R PFAM: SCP-like extracellular; KEGG: SCP-like extracellular; SCP-like extracellular complement(5963435..5964199) Actinosynnema mirum DSM 43827 8329203 YP_003102675.1 CDS Amir_5006 NC_013093.1 5964442 5965722 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ent:Ent638_4061 two-component sensor protein; histidine kinase complement(5964442..5965722) Actinosynnema mirum DSM 43827 8329204 YP_003102676.1 CDS Amir_5007 NC_013093.1 5965719 5966435 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pap:PSPA7_3717 KDP operon transcriptional regulatory protein KdpE; winged helix family two component transcriptional regulator complement(5965719..5966435) Actinosynnema mirum DSM 43827 8329205 YP_003102677.1 CDS Amir_5008 NC_013093.1 5966846 5967412 D KEGG: similar to Ras GTPase-activating protein- binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2); hypothetical protein 5966846..5967412 Actinosynnema mirum DSM 43827 8329206 YP_003102678.1 CDS Amir_5009 NC_013093.1 5967691 5968167 R KEGG: cti:RALTA_A3069 membrane bound protein, weak cytochrome C domains; hypothetical protein complement(5967691..5968167) Actinosynnema mirum DSM 43827 8329207 YP_003102679.1 CDS Amir_5010 NC_013093.1 5968155 5970035 R PFAM: aminoglycoside phosphotransferase; KEGG: bxe:Bxe_A3516 transposase; aminoglycoside phosphotransferase complement(5968155..5970035) Actinosynnema mirum DSM 43827 8329208 YP_003102680.1 CDS Amir_5011 NC_013093.1 5970190 5970402 D hypothetical protein 5970190..5970402 Actinosynnema mirum DSM 43827 8329209 YP_003102681.1 CDS Amir_5012 NC_013093.1 5970511 5971992 D KEGG: mrd:Mrad2831_4352 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 5970511..5971992 Actinosynnema mirum DSM 43827 8329210 YP_003102682.1 CDS Amir_5013 NC_013093.1 5971989 5972759 R PFAM: cyclase family protein; KEGG: hch:HCH_01555 metal-dependent hydrolase; cyclase family protein complement(5971989..5972759) Actinosynnema mirum DSM 43827 8329211 YP_003102683.1 CDS Amir_5014 NC_013093.1 5973146 5974246 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: smd:Smed_2747 alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain-containing protein complement(5973146..5974246) Actinosynnema mirum DSM 43827 8329212 YP_003102684.1 CDS Amir_5015 NC_013093.1 5974243 5974656 R PFAM: thioesterase superfamily protein; KEGG: bmj:BMULJ_01339 thioesterase; thioesterase superfamily protein complement(5974243..5974656) Actinosynnema mirum DSM 43827 8329213 YP_003102685.1 CDS Amir_5016 NC_013093.1 5975219 5976625 D PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: mxa:MXAN_6248 cyclic nucleotide-binding domain protein; Crp/Fnr family transcriptional regulator 5975219..5976625 Actinosynnema mirum DSM 43827 8329214 YP_003102686.1 CDS Amir_5017 NC_013093.1 5976672 5978081 D PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: scl:sce1442 nucleotide-binding protein; Crp/Fnr family transcriptional regulator 5976672..5978081 Actinosynnema mirum DSM 43827 8329215 YP_003102687.1 CDS Amir_5018 NC_013093.1 5978465 5979505 D PFAM: polyprenyl synthetase; KEGG: sfu:Sfum_1417 polyprenyl synthetase; polyprenyl synthetase 5978465..5979505 Actinosynnema mirum DSM 43827 8329216 YP_003102688.1 CDS Amir_5019 NC_013093.1 5979577 5980500 D KEGG: acr:Acry_1832 hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; hydroxymethylbutenyl pyrophosphate reductase 5979577..5980500 Actinosynnema mirum DSM 43827 8329217 YP_003102689.1 CDS Amir_5020 NC_013093.1 5980497 5982353 D PFAM: transketolase; transketolase; KEGG: mgm:Mmc1_1048 1-deoxy-D-xylulose-5-phosphate synthase; transketolase 5980497..5982353 Actinosynnema mirum DSM 43827 8329218 YP_003102690.1 CDS Amir_5021 NC_013093.1 5982456 5983265 D KEGG: rsr-1; SR protein related; hypothetical protein 5982456..5983265 Actinosynnema mirum DSM 43827 8329219 YP_003102691.1 CDS Amir_5022 NC_013093.1 5983470 5983808 D PFAM: protein of unknown function DUF742; hypothetical protein 5983470..5983808 Actinosynnema mirum DSM 43827 8329220 YP_003102692.1 CDS Amir_5023 NC_013093.1 5983891 5984628 R transmembrane anti-sigma factor complement(5983891..5984628) Actinosynnema mirum DSM 43827 8329221 YP_003102693.1 CDS Amir_5024 NC_013093.1 5984634 5985200 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpe:RPE_0795 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit complement(5984634..5985200) Actinosynnema mirum DSM 43827 8329222 YP_003102694.1 CDS Amir_5025 NC_013093.1 5985832 5987058 D PFAM: glycosyl transferase family 2; KEGG: sfu:Sfum_0186 glycosyl transferase, family 2; family 2 glycosyl transferase 5985832..5987058 Actinosynnema mirum DSM 43827 8329223 YP_003102695.1 CDS Amir_5027 NC_013093.1 5987425 5988459 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: rso:RSc0632 NADP-dependent alcohol dehydrogenase oxidoreductase protein; alcohol dehydrogenase GroES domain-containing protein complement(5987425..5988459) Actinosynnema mirum DSM 43827 8329225 YP_003102696.1 CDS Amir_5028 NC_013093.1 5988557 5989141 D PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 5988557..5989141 Actinosynnema mirum DSM 43827 8329226 YP_003102697.1 CDS Amir_5029 NC_013093.1 5989207 5989683 D PFAM: protein of unknown function DUF1232; KEGG: mca:MCA0116 hypothetical protein; hypothetical protein 5989207..5989683 Actinosynnema mirum DSM 43827 8329227 YP_003102698.1 CDS Amir_5030 NC_013093.1 5989648 5990823 R PFAM: conserved hypothetical protein; KEGG: afw:Anae109_3197 hypothetical protein; hypothetical protein complement(5989648..5990823) Actinosynnema mirum DSM 43827 8329228 YP_003102699.1 CDS Amir_5031 NC_013093.1 5990820 5990927 R hypothetical protein complement(5990820..5990927) Actinosynnema mirum DSM 43827 8329229 YP_003102700.1 CDS Amir_5032 NC_013093.1 5991068 5991850 R PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: dar:Daro_0405 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase complement(5991068..5991850) Actinosynnema mirum DSM 43827 8329230 YP_003102701.1 CDS Amir_5033 NC_013093.1 5991988 5993157 D PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver; KEGG: mag:amb3537 serine phosphatase RsbU, regulator of sigma subunit; response regulator receiver modulated serine phosphatase 5991988..5993157 Actinosynnema mirum DSM 43827 8329231 YP_003102702.1 CDS Amir_5034 NC_013093.1 5993160 5994656 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dal:Dalk_3400 histidine kinase; histidine kinase 5993160..5994656 Actinosynnema mirum DSM 43827 8329232 YP_003102703.1 CDS Amir_5035 NC_013093.1 5994653 5995090 D PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mag:amb2979 FOG: CheY-like receiver; response regulator receiver protein 5994653..5995090 Actinosynnema mirum DSM 43827 8329233 YP_003102704.1 CDS Amir_5036 NC_013093.1 5995182 5995937 D KEGG: ade:Adeh_3125 alpha/beta hydrolase fold-1; alpha/beta hydrolase fold-1 5995182..5995937 Actinosynnema mirum DSM 43827 8329234 YP_003102705.1 CDS Amir_5037 NC_013093.1 5996029 5996250 R PFAM: protein of unknown function DUF397; hypothetical protein complement(5996029..5996250) Actinosynnema mirum DSM 43827 8329235 YP_003102706.1 CDS Amir_5038 NC_013093.1 5996247 5997110 R SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein complement(5996247..5997110) Actinosynnema mirum DSM 43827 8329236 YP_003102707.1 CDS Amir_5039 NC_013093.1 5997300 5997644 D hypothetical protein 5997300..5997644 Actinosynnema mirum DSM 43827 8329237 YP_003102708.1 CDS Amir_5040 NC_013093.1 5997598 5997861 R hypothetical protein complement(5997598..5997861) Actinosynnema mirum DSM 43827 8329238 YP_003102709.1 CDS Amir_5041 NC_013093.1 5998125 5998613 R KEGG: hypothetical protein; hypothetical protein complement(5998125..5998613) Actinosynnema mirum DSM 43827 8329239 YP_003102710.1 CDS Amir_5042 NC_013093.1 5998912 5999094 R hypothetical protein complement(5998912..5999094) Actinosynnema mirum DSM 43827 8329240 YP_003102711.1 CDS Amir_5043 NC_013093.1 5999351 6001408 R KEGG: aeh:Mlg_1110 hypothetical protein; superfamily I DNA and RNA helicase-like protein complement(5999351..6001408) Actinosynnema mirum DSM 43827 8329241 YP_003102712.1 CDS Amir_5044 NC_013093.1 6001996 6003132 D KEGG: afw:Anae109_1986 extracellular HAF; hypothetical protein 6001996..6003132 Actinosynnema mirum DSM 43827 8329242 YP_003102713.1 CDS Amir_5045 NC_013093.1 6003391 6003750 R hypothetical protein complement(6003391..6003750) Actinosynnema mirum DSM 43827 8329243 YP_003102714.1 CDS Amir_5046 NC_013093.1 6003870 6004451 R PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator complement(6003870..6004451) Actinosynnema mirum DSM 43827 8329244 YP_003102715.1 CDS Amir_5047 NC_013093.1 6004530 6005375 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bid:Bind_1825 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6004530..6005375 Actinosynnema mirum DSM 43827 8329245 YP_003102716.1 CDS Amir_5048 NC_013093.1 6005410 6006147 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bur:Bcep18194_B1012 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6005410..6006147 Actinosynnema mirum DSM 43827 8329246 YP_003102717.1 CDS Amir_5049 NC_013093.1 6006185 6009280 R PFAM: amidohydrolase; hypothetical protein; KEGG: ade:Adeh_2230 hypothetical protein; amidohydrolase complement(6006185..6009280) Actinosynnema mirum DSM 43827 8329247 YP_003102718.1 CDS Amir_5050 NC_013093.1 6009463 6010116 R hypothetical protein complement(6009463..6010116) Actinosynnema mirum DSM 43827 8329248 YP_003102719.1 CDS Amir_5051 NC_013093.1 6010206 6011885 D PFAM: transposase IS4 family protein; KEGG: mno:Mnod_8094 transposase IS4 family protein; transposase IS4 family protein 6010206..6011885 Actinosynnema mirum DSM 43827 8329249 YP_003102720.1 CDS Amir_5052 NC_013093.1 6011951 6014152 R KEGG: bcz:BCZK2539 UvrD/Rep helicase family protein; superfamily I DNA and RNA helicase-like protein complement(6011951..6014152) Actinosynnema mirum DSM 43827 8329250 YP_003102721.1 CDS Amir_5053 NC_013093.1 6014361 6015176 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: spe:Spro_3426 ABC transporter-related protein; ABC transporter complement(6014361..6015176) Actinosynnema mirum DSM 43827 8329251 YP_003102722.1 CDS Amir_5054 NC_013093.1 6015173 6016204 R PFAM: transport system permease protein; KEGG: ppg:PputGB1_1806 transport system permease protein; transport system permease complement(6015173..6016204) Actinosynnema mirum DSM 43827 8329252 YP_003102723.1 CDS Amir_5055 NC_013093.1 6016201 6017202 R PFAM: transport system permease protein; KEGG: atc:AGR_pAT_449 ferric enterobactin transport protein FepD; transport system permease complement(6016201..6017202) Actinosynnema mirum DSM 43827 8329253 YP_003102724.1 CDS Amir_5056 NC_013093.1 6017298 6018260 R PFAM: PfkB domain protein; KEGG: bha:BH3724 2-keto-3-deoxygluconate kinase; PfkB domain-containing protein complement(6017298..6018260) Actinosynnema mirum DSM 43827 8329254 YP_003102725.1 CDS Amir_5057 NC_013093.1 6018257 6019279 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: gdi:GDI1202 L-idonate 5-dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(6018257..6019279) Actinosynnema mirum DSM 43827 8329255 YP_003102726.1 CDS Amir_5058 NC_013093.1 6019276 6020682 R PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: eca:ECA0919 transport protein; major facilitator superfamily protein complement(6019276..6020682) Actinosynnema mirum DSM 43827 8329256 YP_003102727.1 CDS Amir_5059 NC_013093.1 6020808 6022235 R PFAM: mannitol dehydrogenase domain; mannitol dehydrogenase rossman domain; KEGG: mmr:Mmar10_0223 mannitol dehydrogenase; mannitol dehydrogenase domain-containing protein complement(6020808..6022235) Actinosynnema mirum DSM 43827 8329257 YP_003102728.1 CDS Amir_5060 NC_013093.1 6022232 6023440 R PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0917 starvation sensing mandelate racemase / muconate lactonizing enzyme; mandelate racemase/muconate lactonizing protein complement(6022232..6023440) Actinosynnema mirum DSM 43827 8329258 YP_003102729.1 CDS Amir_5061 NC_013093.1 6024619 6025329 D PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; KEGG: sme:SMa0065 GntR family transcriptional regulator; GntR family transcriptional regulator 6024619..6025329 Actinosynnema mirum DSM 43827 8329259 YP_003102730.1 CDS Amir_5062 NC_013093.1 6025326 6025625 D hypothetical protein 6025326..6025625 Actinosynnema mirum DSM 43827 8329260 YP_003102731.1 CDS Amir_5063 NC_013093.1 6025703 6025897 R PFAM: MbtH domain protein; KEGG: bbt:BBta_4111 hypothetical protein; MbtH domain-containing protein complement(6025703..6025897) Actinosynnema mirum DSM 43827 8329261 YP_003102732.1 CDS Amir_5064 NC_013093.1 6025894 6039243 R TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3636 non-ribosomal peptide synthetase; amino acid adenylation domain-containing protein complement(6025894..6039243) Actinosynnema mirum DSM 43827 8329262 YP_003102733.1 CDS Amir_5065 NC_013093.1 6039351 6040361 R PFAM: periplasmic binding protein; KEGG: atc:AGR_pAT_447 DtxR/iron regulated lipoprotein precursor; periplasmic binding protein complement(6039351..6040361) Actinosynnema mirum DSM 43827 8329263 YP_003102734.1 CDS Amir_5066 NC_013093.1 6040429 6041757 R KEGG: dac:Daci_4749 L-lysine 6-monooxygenase (NADPH); L-lysine 6-monooxygenase (NADPH) complement(6040429..6041757) Actinosynnema mirum DSM 43827 8329264 YP_003102735.1 CDS Amir_5067 NC_013093.1 6041895 6043544 D PFAM: ABC transporter; ABC transporter transmembrane protein; KEGG: met:M446_4330 lipid ABC transporter ATPase/inner membrane protein; ABC transporter 6041895..6043544 Actinosynnema mirum DSM 43827 8329265 YP_003102736.1 CDS Amir_5068 NC_013093.1 6043618 6045618 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: afw:Anae109_3226 ABC transporter; ABC transporter 6043618..6045618 Actinosynnema mirum DSM 43827 8329266 YP_003102737.1 CDS Amir_5069 NC_013093.1 6045677 6046321 D PFAM: beta-lactamase domain protein; KEGG: beta-lactamase domain protein; beta-lactamase domain-containing protein 6045677..6046321 Actinosynnema mirum DSM 43827 8329267 YP_003102738.1 CDS Amir_5070 NC_013093.1 6046382 6047443 R PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: Animal peptidoglycan recognition protein PGRP; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: similar to PGRP-SC1a protein; N-acetylmuramoyl-L-alanine amidase family 2 complement(6046382..6047443) Actinosynnema mirum DSM 43827 8329268 YP_003102739.1 CDS Amir_5071 NC_013093.1 6047597 6048781 R PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_6060 amine oxidase, flavin- containing; amine oxidase complement(6047597..6048781) Actinosynnema mirum DSM 43827 8329269 YP_003102740.1 CDS Amir_5072 NC_013093.1 6048948 6050303 D KEGG: endo-1,4-beta-xylanase; K01181 endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; cellulose- binding family II; SMART: glycoside hydrolase family 10; cellulose- binding family II; endo-1,4-beta-xylanase 6048948..6050303 Actinosynnema mirum DSM 43827 8329270 YP_003102741.1 CDS Amir_5073 NC_013093.1 6050307 6050840 R hypothetical protein complement(6050307..6050840) Actinosynnema mirum DSM 43827 8329271 YP_003102742.1 CDS Amir_5074 NC_013093.1 6050919 6051722 R PFAM: glycoside hydrolase family 16; KEGG: glycoside hydrolase; glycoside hydrolase family protein complement(6050919..6051722) Actinosynnema mirum DSM 43827 8329272 YP_003102743.1 CDS Amir_5075 NC_013093.1 6051936 6052802 R specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein complement(6051936..6052802) Actinosynnema mirum DSM 43827 8329273 YP_003102744.1 CDS Amir_5076 NC_013093.1 6053389 6053505 D hypothetical protein 6053389..6053505 Actinosynnema mirum DSM 43827 8329274 YP_003102745.1 CDS Amir_5077 NC_013093.1 6053634 6054221 D PFAM: lysine exporter protein (LYSE/YGGA); KEGG: smt:Smal_1176 lysine exporter protein (LysE/YggA); lysine exporter protein LysE/YggA 6053634..6054221 Actinosynnema mirum DSM 43827 8329275 YP_003102746.1 CDS Amir_5078 NC_013093.1 6054346 6054978 D PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_1010 bifunctional deaminase- reductase-like; bifunctional deaminase-reductase domain-containing protein 6054346..6054978 Actinosynnema mirum DSM 43827 8329276 YP_003102747.1 CDS Amir_5079 NC_013093.1 6055514 6056065 D KEGG: bcm:Bcenmc03_6355 outer membrane autotransporter; hypothetical protein 6055514..6056065 Actinosynnema mirum DSM 43827 8329277 YP_003102748.1 CDS Amir_5080 NC_013093.1 6056116 6056865 R KEGG: bac:BamMC406_5247 IclR family transcriptional regulator; TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; IclR family transcriptional regulator complement(6056116..6056865) Actinosynnema mirum DSM 43827 8329278 YP_003102749.1 CDS Amir_5081 NC_013093.1 6056858 6057226 R PFAM: carboxymuconolactone decarboxylase; KEGG: mlo:mlr7207 gamma carboxymuconolactone decarboxylase; carboxymuconolactone decarboxylase complement(6056858..6057226) Actinosynnema mirum DSM 43827 8329279 YP_003102750.1 CDS Amir_5082 NC_013093.1 6057223 6057333 R hypothetical protein complement(6057223..6057333) Actinosynnema mirum DSM 43827 8329280 YP_003102751.1 CDS Amir_5083 NC_013093.1 6057442 6058224 R TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; KEGG: swi:Swit_0978 3-oxoadipate enol-lactonase; 3-oxoadipate enol-lactonase complement(6057442..6058224) Actinosynnema mirum DSM 43827 8329281 YP_003102752.1 CDS Amir_5084 NC_013093.1 6058199 6058765 R KEGG: reh:H16_B2290 protocatechuate 3,4-dioxygenase alpha chain; TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase; protocatechuate 3,4-dioxygenase subunit alpha complement(6058199..6058765) Actinosynnema mirum DSM 43827 8329282 YP_003102753.1 CDS Amir_5085 NC_013093.1 6058758 6059474 R KEGG: pfo:Pfl01_1270 protocatechuate 3,4- dioxygenase, beta subunit; TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; protocatechuate 3,4-dioxygenase subunit beta complement(6058758..6059474) Actinosynnema mirum DSM 43827 8329283 YP_003102754.1 CDS Amir_5086 NC_013093.1 6059528 6060283 R PFAM: coenzyme A transferase; KEGG: xcv:XCV0379 glutaconate CoA transferase subunit B; glutaconate CoA-transferase complement(6059528..6060283) Actinosynnema mirum DSM 43827 8329284 YP_003102755.1 CDS Amir_5087 NC_013093.1 6060280 6061077 R PFAM: coenzyme A transferase; KEGG: pag:PLES_02231 CoA transferase, subunit A; coenzyme A transferase complement(6060280..6061077) Actinosynnema mirum DSM 43827 8329285 YP_003102756.1 CDS Amir_5088 NC_013093.1 6061235 6061837 D KEGG: noc:Noc_2708 hypothetical protein; hypothetical protein 6061235..6061837 Actinosynnema mirum DSM 43827 8329286 YP_003102757.1 CDS Amir_5089 NC_013093.1 6061834 6065136 D SMART: ATPase AAA; KEGG: met:M446_5114 ATPase AAA; ATPase AAA 6061834..6065136 Actinosynnema mirum DSM 43827 8329287 YP_003102758.1 CDS Amir_5090 NC_013093.1 6065558 6067021 R PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: gsu:GSU0700 sensory box/response regulator; protein serine/threonine phosphatase complement(6065558..6067021) Actinosynnema mirum DSM 43827 8329288 YP_003102759.1 CDS Amir_5091 NC_013093.1 6067224 6071663 D KEGG: ank:AnaeK_4253 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; GAF sensor hybrid histidine kinase 6067224..6071663 Actinosynnema mirum DSM 43827 8329289 YP_003102760.1 CDS Amir_5092 NC_013093.1 6071713 6072039 R TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mca:MCA1686 anti-sigma B factor antagonist; anti-sigma-factor antagonist complement(6071713..6072039) Actinosynnema mirum DSM 43827 8329290 YP_003102761.1 CDS Amir_5093 NC_013093.1 6072173 6072571 D PFAM: ATP-binding region ATPase domain protein; KEGG: met:M446_2753 signal transduction histidine kinase; anti-sigma regulatory factor, serine/threonine protein kinase 6072173..6072571 Actinosynnema mirum DSM 43827 8329291 YP_003102762.1 CDS Amir_5094 NC_013093.1 6073230 6074144 D PFAM: Ppx/GppA phosphatase; KEGG: acp:A2cp1_0693 Ppx/GppA phosphatase; Ppx/GppA phosphatase 6073230..6074144 Actinosynnema mirum DSM 43827 8329292 YP_003102763.1 CDS Amir_5095 NC_013093.1 6074158 6074544 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sus:Acid_2843 anti-sigma-factor antagonist; anti-sigma-factor antagonist 6074158..6074544 Actinosynnema mirum DSM 43827 8329293 YP_003102764.1 CDS Amir_5096 NC_013093.1 6074578 6074958 D hypothetical protein 6074578..6074958 Actinosynnema mirum DSM 43827 8329294 YP_003102765.1 CDS Amir_5097 NC_013093.1 6074970 6075452 D PFAM: GCN5-related N-acetyltransferase; KEGG: pzu:PHZ_c2921 acetyltransferase, GNAT family; GCN5-like N-acetyltransferase 6074970..6075452 Actinosynnema mirum DSM 43827 8329295 YP_003102766.1 CDS Amir_5098 NC_013093.1 6075665 6076804 D PFAM: luciferase-like monooxygenase; KEGG: mpo:Mpop_1275 dehydrogenase protein; luciferase-like monooxygenase 6075665..6076804 Actinosynnema mirum DSM 43827 8329296 YP_003102767.1 CDS Amir_5099 NC_013093.1 6076852 6077040 D hypothetical protein 6076852..6077040 Actinosynnema mirum DSM 43827 8329297 YP_003102768.1 CDS Amir_5100 NC_013093.1 6077133 6077522 R KEGG: TIMP2; TIMP metallopeptidase inhibitor 2; TIMP2; TIMP metallopeptidase inhibitor 2 complement(6077133..6077522) Actinosynnema mirum DSM 43827 8329298 YP_003102769.1 CDS Amir_5101 NC_013093.1 6077591 6077713 D hypothetical protein 6077591..6077713 Actinosynnema mirum DSM 43827 8329299 YP_003102770.1 CDS Amir_5102 NC_013093.1 6077809 6078789 D KEGG: vei:Veis_1391 periplasmic binding protein/LacI transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 6077809..6078789 Actinosynnema mirum DSM 43827 8329300 YP_003102771.1 CDS Amir_5103 NC_013093.1 6078905 6079810 D PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: peptidase U61, LD-carboxypeptidase A; peptidase U61 LD-carboxypeptidase A 6078905..6079810 Actinosynnema mirum DSM 43827 8329301 YP_003102772.1 CDS Amir_5104 NC_013093.1 6080073 6080927 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: pag:PLES_17341 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(6080073..6080927) Actinosynnema mirum DSM 43827 8329302 YP_003102773.1 CDS Amir_5105 NC_013093.1 6080997 6081590 D PFAM: regulatory protein TetR; KEGG: met:M446_2111 TetR family transcriptional regulator; TetR family transcriptional regulator 6080997..6081590 Actinosynnema mirum DSM 43827 8329303 YP_003102774.1 CDS Amir_5106 NC_013093.1 6081622 6082356 R hypothetical protein complement(6081622..6082356) Actinosynnema mirum DSM 43827 8329304 YP_003102775.1 CDS Amir_5107 NC_013093.1 6082824 6083339 D PFAM: chitin-binding domain 3 protein; KEGG: hch:HCH_03973 N-acetylglucosamine-binding protein A; chitin-binding domain 3 protein 6082824..6083339 Actinosynnema mirum DSM 43827 8329305 YP_003102776.1 CDS Amir_5108 NC_013093.1 6083782 6083946 D hypothetical protein 6083782..6083946 Actinosynnema mirum DSM 43827 8329306 YP_003102777.1 CDS Amir_5109 NC_013093.1 6083946 6085697 D KEGG: GK22681 gene product from transcript GK22681- RA; hypothetical protein 6083946..6085697 Actinosynnema mirum DSM 43827 8329307 YP_003102778.1 CDS Amir_5110 NC_013093.1 6086748 6086921 R PFAM: CsbD family protein; KEGG: pen:PSEEN4005 hypothetical protein; CsbD family protein complement(6086748..6086921) Actinosynnema mirum DSM 43827 8329308 YP_003102779.1 CDS Amir_5111 NC_013093.1 6087207 6087698 D PFAM: ANTAR domain protein; ANTAR domain-containing protein with unknown sensor 6087207..6087698 Actinosynnema mirum DSM 43827 8329309 YP_003102780.1 CDS Amir_5112 NC_013093.1 6087647 6089539 R KEGG: gsu:GSU2358 isoamylase family protein; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; malto-oligosyltrehalose trehalohydrolase complement(6087647..6089539) Actinosynnema mirum DSM 43827 8329310 YP_003102781.1 CDS Amir_5113 NC_013093.1 6089536 6091785 R KEGG: reu:Reut_B4234 alpha amylase domain- containing protein; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; malto-oligosyltrehalose synthase complement(6089536..6091785) Actinosynnema mirum DSM 43827 8329311 YP_003102782.1 CDS Amir_5114 NC_013093.1 6091782 6093908 R KEGG: nmu:Nmul_A1401 glycogen debranching protein GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; glycogen debranching protein GlgX complement(6091782..6093908) Actinosynnema mirum DSM 43827 8329312 YP_003102783.1 CDS Amir_5115 NC_013093.1 6094069 6094407 R hypothetical protein complement(6094069..6094407) Actinosynnema mirum DSM 43827 8329313 YP_003102784.1 CDS Amir_5116 NC_013093.1 6094512 6096590 R KEGG: bpt:Bpet2366 hypothetical protein; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; 4-alpha-glucanotransferase complement(6094512..6096590) Actinosynnema mirum DSM 43827 8329314 YP_003102785.1 CDS Amir_5117 NC_013093.1 6096709 6097671 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SM_b20014 transcriptional regulator protein; LacI family transcriptional regulator complement(6096709..6097671) Actinosynnema mirum DSM 43827 8329315 YP_003102786.1 CDS Amir_5118 NC_013093.1 6097783 6098235 D PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: afw:Anae109_2778 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 6097783..6098235 Actinosynnema mirum DSM 43827 8329316 YP_003102787.1 CDS Amir_5119 NC_013093.1 6098239 6099222 R PFAM: luciferase-like monooxygenase; KEGG: pzu:PHZ_c2545 5,10- methylenetetrahydromethanopterin reductase; luciferase-like monooxygenase complement(6098239..6099222) Actinosynnema mirum DSM 43827 8329317 YP_003102788.1 CDS Amir_5120 NC_013093.1 6099506 6100372 R PFAM: peptidase M23; KEGG: pde:Pden_4473 peptidase M23B; peptidase M23 complement(6099506..6100372) Actinosynnema mirum DSM 43827 8329318 YP_003102789.1 CDS Amir_5121 NC_013093.1 6100961 6103042 R PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: rce:RC1_2700 penicillin-binding protein, 1A family; glycosyl transferase family protein complement(6100961..6103042) Actinosynnema mirum DSM 43827 8329319 YP_003102790.1 CDS Amir_5122 NC_013093.1 6103337 6104380 R PFAM: PfkB domain protein; KEGG: sme:SM_b21462 sugar kinase protein; PfkB domain-containing protein complement(6103337..6104380) Actinosynnema mirum DSM 43827 8329320 YP_003102791.1 CDS Amir_5123 NC_013093.1 6104393 6105124 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: pla:Plav_0951 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit complement(6104393..6105124) Actinosynnema mirum DSM 43827 8329321 YP_003102792.1 CDS Amir_5124 NC_013093.1 6105572 6106390 D PFAM: alpha/beta hydrolase fold; KEGG: mrd:Mrad2831_0619 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 6105572..6106390 Actinosynnema mirum DSM 43827 8329322 YP_003102793.1 CDS Amir_5126 NC_013093.1 6106632 6107186 D KEGG: pap:PSPA7_5262 hypothetical protein; hypothetical protein 6106632..6107186 Actinosynnema mirum DSM 43827 8329324 YP_003102794.1 CDS Amir_5127 NC_013093.1 6107179 6108075 R PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; LysR family transcriptional regulator complement(6107179..6108075) Actinosynnema mirum DSM 43827 8329325 YP_003102795.1 CDS Amir_5128 NC_013093.1 6108096 6108908 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mll2997 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 6108096..6108908 Actinosynnema mirum DSM 43827 8329326 YP_003102796.1 CDS Amir_5129 NC_013093.1 6108954 6109718 R PFAM: regulatory protein DeoR; regulatory protein GntR HTH; SMART: regulatory protein DeoR; KEGG: aba:Acid345_0659 transcriptional regulator, DeoR family; DeoR family transcriptional regulator complement(6108954..6109718) Actinosynnema mirum DSM 43827 8329327 YP_003102797.1 CDS Amir_5130 NC_013093.1 6109816 6110553 D KEGG: bha:BH0227 hypothetical protein; hypothetical protein 6109816..6110553 Actinosynnema mirum DSM 43827 8329328 YP_003102798.1 CDS Amir_5131 NC_013093.1 6111091 6113037 R PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: sat:SYN_01564 phospholipid-lipopolysaccharide ABC transporter; ABC transporter complement(6111091..6113037) Actinosynnema mirum DSM 43827 8329329 YP_003102799.1 CDS Amir_5132 NC_013093.1 6113533 6114342 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: dal:Dalk_3354 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase complement(6113533..6114342) Actinosynnema mirum DSM 43827 8329330 YP_003102800.1 CDS Amir_5133 NC_013093.1 6114412 6114621 R transcriptional regulator complement(6114412..6114621) Actinosynnema mirum DSM 43827 8329331 YP_003102801.1 CDS Amir_5134 NC_013093.1 6114785 6116413 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6041 ABC transporter, ATP-binding protein; ABC transporter complement(6114785..6116413) Actinosynnema mirum DSM 43827 8329332 YP_003102802.1 CDS fabG NC_013093.1 6116622 6117377 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 6116622..6117377 Actinosynnema mirum DSM 43827 8329333 YP_003102803.1 CDS Amir_5136 NC_013093.1 6117418 6117855 R KEGG: scl:sce9133 secreted protein; hypothetical protein complement(6117418..6117855) Actinosynnema mirum DSM 43827 8329334 YP_003102804.1 CDS Amir_5137 NC_013093.1 6117848 6118363 R TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: xau:Xaut_1595 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit complement(6117848..6118363) Actinosynnema mirum DSM 43827 8329335 YP_003102805.1 CDS Amir_5138 NC_013093.1 6118368 6118742 R KEGG: similar to mucin 2; K10955 intestinal mucin- 2; hypothetical protein complement(6118368..6118742) Actinosynnema mirum DSM 43827 8329336 YP_003102806.1 CDS Amir_5139 NC_013093.1 6118859 6119437 R KEGG: bur:Bcep18194_A4859 hypothetical protein; hypothetical protein complement(6118859..6119437) Actinosynnema mirum DSM 43827 8329337 YP_003102807.1 CDS Amir_5140 NC_013093.1 6119672 6120649 D hypothetical protein 6119672..6120649 Actinosynnema mirum DSM 43827 8329338 YP_003102808.1 CDS Amir_5141 NC_013093.1 6120837 6123653 R PFAM: proprotein convertase P; KEGG: aba:Acid345_4222 hypothetical protein; proprotein convertase P complement(6120837..6123653) Actinosynnema mirum DSM 43827 8329339 YP_003102809.1 CDS Amir_5142 NC_013093.1 6123800 6125368 R KEGG: aba:Acid345_0225 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; deoxyguanosinetriphosphate triphosphohydrolase complement(6123800..6125368) Actinosynnema mirum DSM 43827 8329340 YP_003102810.1 CDS Amir_5143 NC_013093.1 6131515 6132954 D PFAM: MASE1 domain protein; KEGG: sse:Ssed_3344 signal transduction protein; integral membrane sensor protein 6131515..6132954 Actinosynnema mirum DSM 43827 8329345 YP_003102811.1 CDS Amir_5144 NC_013093.1 6132958 6134037 D TIGRFAM: lycopene cyclase family protein; PFAM: Lycopene beta and epsilon cyclase; KEGG: hypothetical protein; K06443 lycopene beta cyclase; lycopene cyclase family protein 6132958..6134037 Actinosynnema mirum DSM 43827 8329346 YP_003102812.1 CDS Amir_5145 NC_013093.1 6134080 6135777 D KEGG: cti:RALTA_B1157 diguanylate cyclase (GGDEF domain) and C-di-GMP phosphodiesterase (EAL domain)); TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; diguanylate cyclase/phosphodiesterase 6134080..6135777 Actinosynnema mirum DSM 43827 8329347 YP_003102813.1 CDS Amir_5146 NC_013093.1 6135991 6137112 D PFAM: glutamate--cysteine ligase GCS2; KEGG: jan:Jann_1911 carboxylate-amine ligase; glutamate--cysteine ligase GCS2 6135991..6137112 Actinosynnema mirum DSM 43827 8329348 YP_003102814.1 CDS Amir_5147 NC_013093.1 6137184 6137597 D PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: bph:Bphy_4760 CBS domain-containing protein; signal transduction protein with CBS domains 6137184..6137597 Actinosynnema mirum DSM 43827 8329349 YP_003102815.1 CDS Amir_5148 NC_013093.1 6137682 6138077 R PFAM: protein of unknown function DUF59; KEGG: eli:ELI_12745 metal-sulfur cluster biosynthetic enzyme; hypothetical protein complement(6137682..6138077) Actinosynnema mirum DSM 43827 8329350 YP_003102816.1 CDS Amir_5149 NC_013093.1 6138074 6138517 R TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: bsu:BSU32680 hypothetical protein; SUF system FeS assembly protein, NifU family complement(6138074..6138517) Actinosynnema mirum DSM 43827 8329351 YP_003102817.1 CDS Amir_5150 NC_013093.1 6138517 6139794 R TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; KEGG: acr:Acry_2269 SufS subfamily cysteine desulfurase; SufS subfamily cysteine desulfurase complement(6138517..6139794) Actinosynnema mirum DSM 43827 8329352 YP_003102818.1 CDS Amir_5151 NC_013093.1 6139858 6140631 R KEGG: bat:BAS4851 ABC transporter, ATP-binding protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; SMART: ATPase AAA; FeS assembly ATPase SufC complement(6139858..6140631) Actinosynnema mirum DSM 43827 8329353 YP_003102819.1 CDS Amir_5152 NC_013093.1 6140669 6140995 R PFAM: Rieske [2Fe-2S] domain protein; KEGG: bmn:BMA10247_A0236 aromatic-ring- hydroxylating dioxygenase, ferredoxin subunit; Rieske (2Fe-2S) domain-containing protein complement(6140669..6140995) Actinosynnema mirum DSM 43827 8329354 YP_003102820.1 CDS Amir_5153 NC_013093.1 6140992 6142164 R TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: mxa:MXAN_1155 FeS assembly protein SufD; FeS assembly protein SufD complement(6140992..6142164) Actinosynnema mirum DSM 43827 8329355 YP_003102821.1 CDS Amir_5154 NC_013093.1 6142166 6143611 R TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: bcz:BCZK4703 iron-regulated ABC transporter; FeS assembly protein SufB complement(6142166..6143611) Actinosynnema mirum DSM 43827 8329356 YP_003102822.1 CDS Amir_5155 NC_013093.1 6143608 6144324 R PFAM: Helix-turn-helix type 11 domain protein; KEGG: ypk:y4095 hypothetical protein; transcriptional regulator complement(6143608..6144324) Actinosynnema mirum DSM 43827 8329357 YP_003102823.1 CDS Amir_5156 NC_013093.1 6144522 6145559 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_0865 oxidoreductase, short chain dehydrogenase/reductase family; short-chain dehydrogenase/reductase SDR 6144522..6145559 Actinosynnema mirum DSM 43827 8329358 YP_003102824.1 CDS Amir_5157 NC_013093.1 6145570 6146151 D PFAM: regulatory protein TetR; KEGG: msl:Msil_3313 transcriptional regulator, TetR family; TetR family transcriptional regulator 6145570..6146151 Actinosynnema mirum DSM 43827 8329359 YP_003102825.1 CDS Amir_5158 NC_013093.1 6146256 6147839 D KEGG: met:M446_4899 hypothetical protein; hypothetical protein 6146256..6147839 Actinosynnema mirum DSM 43827 8329360 YP_003102826.1 CDS Amir_5159 NC_013093.1 6147996 6151958 D PFAM: Patatin; KEGG: bpm:BURPS1710b_1675 patatin family phospholipase; patatin 6147996..6151958 Actinosynnema mirum DSM 43827 8329361 YP_003102827.1 CDS Amir_5160 NC_013093.1 6151901 6154303 R PFAM: glycosyl transferase group 1; KEGG: lpc:LPC_1061 glycosyltransferase; group 1 glycosyl transferase complement(6151901..6154303) Actinosynnema mirum DSM 43827 8329362 YP_003102828.1 CDS Amir_5161 NC_013093.1 6154300 6154911 R KEGG: dvm:DvMF_2468 molybdopterin-containing oxidoreductase membrane anchor subunit; hypothetical protein complement(6154300..6154911) Actinosynnema mirum DSM 43827 8329363 YP_003102829.1 CDS Amir_5162 NC_013093.1 6155048 6155986 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mxa:MXAN_1597 ABC transporter, ATP-binding protein; ABC transporter 6155048..6155986 Actinosynnema mirum DSM 43827 8329364 YP_003102830.1 CDS Amir_5163 NC_013093.1 6155983 6156756 D PFAM: ABC transporter; KEGG: scl:sce5572 integral membrane transport protein; ABC transporter 6155983..6156756 Actinosynnema mirum DSM 43827 8329365 YP_003102831.1 CDS Amir_5164 NC_013093.1 6156972 6157802 D KEGG: Sfrs15; splicing factor, arginine/serine-rich 15; hypothetical protein 6156972..6157802 Actinosynnema mirum DSM 43827 8329366 YP_003102832.1 CDS Amir_5165 NC_013093.1 6157799 6158122 D hypothetical protein 6157799..6158122 Actinosynnema mirum DSM 43827 8329367 YP_003102833.1 CDS Amir_5166 NC_013093.1 6158126 6159247 D KEGG: pfo:Pfl01_4833 chemotaxis sensory transducer; hypothetical protein 6158126..6159247 Actinosynnema mirum DSM 43827 8329368 YP_003102834.1 CDS Amir_5167 NC_013093.1 6159247 6160092 D hypothetical protein 6159247..6160092 Actinosynnema mirum DSM 43827 8329369 YP_003102835.1 CDS Amir_5168 NC_013093.1 6160290 6161258 D PFAM: cytochrome oxidase assembly; KEGG: noc:Noc_3040 cytochrome oxidase assembly; cytochrome oxidase assembly 6160290..6161258 Actinosynnema mirum DSM 43827 8329370 YP_003102836.1 CDS Amir_5169 NC_013093.1 6161201 6161659 R SMART: regulatory protein ArsR; KEGG: scl:sce6114 hypothetical protein; ArsR family transcriptional regulator complement(6161201..6161659) Actinosynnema mirum DSM 43827 8329371 YP_003102837.1 CDS Amir_5170 NC_013093.1 6161792 6162595 R PFAM: protein of unknown function DUF742; KEGG: Hypothetical protein CBG22207; hypothetical protein complement(6161792..6162595) Actinosynnema mirum DSM 43827 8329372 YP_003102838.1 CDS Amir_5171 NC_013093.1 6162606 6163049 R PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_0367 roadblock/LC7 family protein; Roadblock/LC7 family protein complement(6162606..6163049) Actinosynnema mirum DSM 43827 8329373 YP_003102839.1 CDS Amir_5172 NC_013093.1 6163046 6166117 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: rpe:RPE_2275 peptidase C14, caspase catalytic subunit P20; sensor with HAMP domain complement(6163046..6166117) Actinosynnema mirum DSM 43827 8329374 YP_003102840.1 CDS Amir_5173 NC_013093.1 6166459 6166878 D PFAM: protein of unknown function DUF485; KEGG: sus:Acid_0924 hypothetical protein; hypothetical protein 6166459..6166878 Actinosynnema mirum DSM 43827 8329375 YP_003102841.1 CDS Amir_5174 NC_013093.1 6166878 6168455 D TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: dvm:DvMF_0315 SSS sodium solute transporter superfamily; SSS sodium solute transporter superfamily protein 6166878..6168455 Actinosynnema mirum DSM 43827 8329376 YP_003102842.1 CDS Amir_5175 NC_013093.1 6168549 6169409 R KEGG: tmz:Tmz1t_1794 hypothetical protein; hypothetical protein complement(6168549..6169409) Actinosynnema mirum DSM 43827 8329377 YP_003102843.1 CDS Amir_5176 NC_013093.1 6169406 6169693 R hypothetical protein complement(6169406..6169693) Actinosynnema mirum DSM 43827 8329378 YP_003102844.1 CDS Amir_5177 NC_013093.1 6169708 6171339 D PFAM: protein of unknown function DUF885; KEGG: mxa:MXAN_0186 lipoprotein; hypothetical protein 6169708..6171339 Actinosynnema mirum DSM 43827 8329379 YP_003102845.1 CDS Amir_5178 NC_013093.1 6171538 6172509 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bte:BTH_II0233 quinone oxidoreductase; alcohol dehydrogenase zinc-binding domain-containing protein 6171538..6172509 Actinosynnema mirum DSM 43827 8329380 YP_003102846.1 CDS Amir_5179 NC_013093.1 6172660 6173247 R PFAM: peptidylprolyl isomerase FKBP-type; KEGG: scl:sce3796 FKBP-type peptidyl-prolyl cis- trans isomerase; FKBP-type peptidylprolyl isomerase complement(6172660..6173247) Actinosynnema mirum DSM 43827 8329381 YP_003102847.1 CDS Amir_5180 NC_013093.1 6173453 6174460 D hypothetical protein 6173453..6174460 Actinosynnema mirum DSM 43827 8329382 YP_003102848.1 CDS Amir_5181 NC_013093.1 6174467 6175114 D hypothetical protein 6174467..6175114 Actinosynnema mirum DSM 43827 8329383 YP_003102849.1 CDS Amir_5182 NC_013093.1 6175382 6176020 D KEGG: bsu:BSU21890 hypothetical protein; hypothetical protein 6175382..6176020 Actinosynnema mirum DSM 43827 8329384 YP_003102850.1 CDS Amir_5183 NC_013093.1 6176139 6176789 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: mno:Mnod_5360 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 6176139..6176789 Actinosynnema mirum DSM 43827 8329385 YP_003102851.1 CDS Amir_5184 NC_013093.1 6177402 6177782 D KEGG: eca:ECA0122 hypothetical protein; hypothetical protein 6177402..6177782 Actinosynnema mirum DSM 43827 8329386 YP_003102852.1 CDS Amir_5185 NC_013093.1 6177895 6178818 R TIGRFAM: protoheme IX farnesyltransferase; PFAM: UbiA prenyltransferase; KEGG: rce:RC1_3632 protoheme IX farnesyltransferase; protoheme IX farnesyltransferase complement(6177895..6178818) Actinosynnema mirum DSM 43827 8329387 YP_003102853.1 CDS Amir_5186 NC_013093.1 6179098 6181191 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 6179098..6181191 Actinosynnema mirum DSM 43827 8329388 YP_003102854.1 CDS Amir_5187 NC_013093.1 6181224 6182336 D TIGRFAM: transaldolase; PFAM: transaldolase; KEGG: aba:Acid345_2810 bifunctional transaldolase/phosoglucose isomerase; transaldolase 6181224..6182336 Actinosynnema mirum DSM 43827 8329389 YP_003102855.1 CDS Amir_5188 NC_013093.1 6182339 6183958 D PFAM: phosphoglucose isomerase (PGI); KEGG: mno:Mnod_7445 transaldolase; phosphoglucose isomerase (PGI) 6182339..6183958 Actinosynnema mirum DSM 43827 8329390 YP_003102856.1 CDS Amir_5189 NC_013093.1 6183955 6185496 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 6183955..6185496 Actinosynnema mirum DSM 43827 8329391 YP_003102857.1 CDS Amir_5190 NC_013093.1 6185493 6186632 D TIGRFAM: OpcA protein; KEGG: sus:Acid_5280 glucose-6-P dehydrogenase subunit-like protein; OpcA protein 6185493..6186632 Actinosynnema mirum DSM 43827 8329392 YP_003102858.1 CDS Amir_5191 NC_013093.1 6186629 6187408 D TIGRFAM: 6-phosphogluconolactonase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: gdi:GDI0291 6-phosphogluconolactonase; 6-phosphogluconolactonase 6186629..6187408 Actinosynnema mirum DSM 43827 8329393 YP_003102859.1 CDS Amir_5192 NC_013093.1 6187858 6189195 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 6187858..6189195 Actinosynnema mirum DSM 43827 8329394 YP_003102860.1 CDS Amir_5193 NC_013093.1 6189582 6190907 R KEGG: GI19648 gene product from transcript GI19648- RA; hypothetical protein complement(6189582..6190907) Actinosynnema mirum DSM 43827 8329395 YP_003102861.1 CDS Amir_5194 NC_013093.1 6190952 6191893 D KEGG: YALI0C10450p; hypothetical protein 6190952..6191893 Actinosynnema mirum DSM 43827 8329396 YP_003102862.1 CDS Amir_5195 NC_013093.1 6191977 6192273 R hypothetical protein complement(6191977..6192273) Actinosynnema mirum DSM 43827 8329397 YP_003102863.1 CDS secG NC_013093.1 6192373 6192606 R TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: pne:Pnec_0820 preprotein translocase, SecG subunit; preprotein translocase subunit SecG complement(6192373..6192606) Actinosynnema mirum DSM 43827 8329398 YP_003102864.1 CDS Amir_5197 NC_013093.1 6192700 6193485 R KEGG: bsu:BSU33920 triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; triosephosphate isomerase complement(6192700..6193485) Actinosynnema mirum DSM 43827 8329399 YP_003102865.1 CDS Amir_5198 NC_013093.1 6193487 6194653 R PFAM: phosphoglycerate kinase; KEGG: bsu:BSU33930 phosphoglycerate kinase; phosphoglycerate kinase complement(6193487..6194653) Actinosynnema mirum DSM 43827 8329400 YP_003102866.1 CDS Amir_5199 NC_013093.1 6194673 6195677 R KEGG: bha:BH3560 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase, type I complement(6194673..6195677) Actinosynnema mirum DSM 43827 8329401 YP_003102867.1 CDS Amir_5200 NC_013093.1 6196043 6197023 R KEGG: PHC10; cell wall protein pherophorin-C10; hypothetical protein complement(6196043..6197023) Actinosynnema mirum DSM 43827 8329402 YP_003102868.1 CDS Amir_5201 NC_013093.1 6197113 6197244 R hypothetical protein complement(6197113..6197244) Actinosynnema mirum DSM 43827 8329403 YP_003102869.1 CDS Amir_5202 NC_013093.1 6197329 6198534 R KEGG: scl:sce6476 hypothetical protein; hypothetical protein complement(6197329..6198534) Actinosynnema mirum DSM 43827 8329404 YP_003102870.1 CDS Amir_5203 NC_013093.1 6198662 6199648 R PFAM: protein of unknown function DUF199; KEGG: bsu:BSU34750 hypothetical protein; hypothetical protein complement(6198662..6199648) Actinosynnema mirum DSM 43827 8329405 YP_003102871.1 CDS Amir_5204 NC_013093.1 6199639 6200691 R PFAM: protein of unknown function UPF0052 and CofD; KEGG: afw:Anae109_2613 protein of unknown function UPF0052 and CofD; hypothetical protein complement(6199639..6200691) Actinosynnema mirum DSM 43827 8329406 YP_003102872.1 CDS Amir_5205 NC_013093.1 6200688 6201575 R PFAM: conserved hypothetical protein; KEGG: afw:Anae109_0152 hypothetical protein; hypothetical protein complement(6200688..6201575) Actinosynnema mirum DSM 43827 8329407 YP_003102873.1 CDS Amir_5206 NC_013093.1 6201572 6203521 R KEGG: tgr:Tgr7_1907 excinuclease ABC subunit C; TIGRFAM: excinuclease ABC, C subunit; PFAM: excinuclease ABC C subunit domain protein; Excinuclease ABC C subunit domain protein; helix-hairpin- helix motif; UvrB/UvrC protein; SMART: Excinuclease ABC C subunit domain protein; Helix-hairpin-helix DNA-binding class 1; excinuclease ABC subunit C complement(6201572..6203521) Actinosynnema mirum DSM 43827 8329408 YP_003102874.1 CDS Amir_5207 NC_013093.1 6203863 6204378 R PFAM: Rieske [2Fe-2S] domain protein; KEGG: bxe:Bxe_B1329 dioxygenase, ferredoxin reductase component; Rieske (2Fe-2S) domain-containing protein complement(6203863..6204378) Actinosynnema mirum DSM 43827 8329409 YP_003102875.1 CDS Amir_5208 NC_013093.1 6204629 6205039 R PFAM: Rieske [2Fe-2S] domain protein; KEGG: xcv:XCV3420 Rieske 2Fe-2S family protein; Rieske (2Fe-2S) domain-containing protein complement(6204629..6205039) Actinosynnema mirum DSM 43827 8329410 YP_003102876.1 CDS Amir_5209 NC_013093.1 6205919 6206410 R hypothetical protein complement(6205919..6206410) Actinosynnema mirum DSM 43827 8329411 YP_003102877.1 CDS Amir_5210 NC_013093.1 6206655 6208247 D XRE family transcriptional regulator 6206655..6208247 Actinosynnema mirum DSM 43827 8329412 YP_003102878.1 CDS Amir_5211 NC_013093.1 6208247 6208744 D KEGG: bxe:Bxe_C1257 hypothetical protein; hypothetical protein 6208247..6208744 Actinosynnema mirum DSM 43827 8329413 YP_003102879.1 CDS Amir_5212 NC_013093.1 6208808 6209761 D PFAM: Helix-turn-helix type 11 domain protein; KEGG: scl:sce5223 DeoR family transcriptional regulator; Helix-turn-helix type 11 domain-containing protein 6208808..6209761 Actinosynnema mirum DSM 43827 8329414 YP_003102880.1 CDS Amir_5213 NC_013093.1 6209768 6210709 R hypothetical protein complement(6209768..6210709) Actinosynnema mirum DSM 43827 8329415 YP_003102881.1 CDS Amir_5214 NC_013093.1 6210709 6211206 R TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: pca:Pcar_3124 RNA polymerase, sigma-E factor; ECF subfamily RNA polymerase sigma-24 subunit complement(6210709..6211206) Actinosynnema mirum DSM 43827 8329416 YP_003102882.1 CDS Amir_5215 NC_013093.1 6211360 6212712 R PFAM: peptidase M28; peptidase M20; KEGG: bcy:Bcer98_3876 peptidase M28; peptidase M28 complement(6211360..6212712) Actinosynnema mirum DSM 43827 8329417 YP_003102883.1 CDS Amir_5216 NC_013093.1 6212815 6213291 R hypothetical protein complement(6212815..6213291) Actinosynnema mirum DSM 43827 8329418 YP_003102884.1 CDS Amir_5217 NC_013093.1 6213288 6213770 R KEGG: dds:Ddes_1621 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; 6,7-dimethyl-8-ribityllumazine synthase complement(6213288..6213770) Actinosynnema mirum DSM 43827 8329419 YP_003102885.1 CDS Amir_5218 NC_013093.1 6213767 6215020 R KEGG: ATGCH; ATGCH (ARABIDOPSIS THALIANA GTP CYCLOHYDROLASE II); 3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP cyclohydrolase II; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(6213767..6215020) Actinosynnema mirum DSM 43827 8329420 YP_003102886.1 CDS Amir_5219 NC_013093.1 6215017 6215655 R TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: hap:HAPS_1135 riboflavin synthase subunit alpha; riboflavin synthase subunit alpha complement(6215017..6215655) Actinosynnema mirum DSM 43827 8329421 YP_003102887.1 CDS Amir_5220 NC_013093.1 6215763 6216413 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(6215763..6216413) Actinosynnema mirum DSM 43827 8329422 YP_003102888.1 CDS Amir_5221 NC_013093.1 6216688 6218796 R KEGG: acp:A2cp1_3940 hypothetical protein; hypothetical protein complement(6216688..6218796) Actinosynnema mirum DSM 43827 8329423 YP_003102889.1 CDS Amir_5222 NC_013093.1 6218903 6219448 R PFAM: flavoprotein; KEGG: xau:Xaut_0078 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; flavoprotein complement(6218903..6219448) Actinosynnema mirum DSM 43827 8329424 YP_003102890.1 CDS Amir_5223 NC_013093.1 6219516 6220952 R PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: ade:Adeh_3970 NusB/RsmB/TIM44 family protein; Fmu (Sun) domain-containing protein complement(6219516..6220952) Actinosynnema mirum DSM 43827 8329425 YP_003102891.1 CDS Amir_5224 NC_013093.1 6220949 6221881 R TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: mca:MCA2844 methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase complement(6220949..6221881) Actinosynnema mirum DSM 43827 8329426 YP_003102892.1 CDS def NC_013093.1 6221883 6222428 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(6221883..6222428) Actinosynnema mirum DSM 43827 8329427 YP_003102893.1 CDS Amir_5226 NC_013093.1 6223044 6223148 D hypothetical protein 6223044..6223148 Actinosynnema mirum DSM 43827 8329428 YP_003102894.1 CDS Amir_5227 NC_013093.1 6223159 6223293 R hypothetical protein complement(6223159..6223293) Actinosynnema mirum DSM 43827 8329429 YP_003102895.1 CDS Amir_5228 NC_013093.1 6223507 6224046 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: pla:Plav_1868 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit 6223507..6224046 Actinosynnema mirum DSM 43827 8329430 YP_003102896.1 CDS Amir_5229 NC_013093.1 6224515 6225216 D hypothetical protein 6224515..6225216 Actinosynnema mirum DSM 43827 8329431 YP_003102897.1 CDS Amir_5230 NC_013093.1 6225194 6225622 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; KEGG: pzu:PHZ_c1529 RNA polymerase sigma-70 factor,ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 6225194..6225622 Actinosynnema mirum DSM 43827 8329432 YP_003102898.1 CDS Amir_5231 NC_013093.1 6225619 6226830 D hypothetical protein 6225619..6226830 Actinosynnema mirum DSM 43827 8329433 YP_003102899.1 CDS Amir_5232 NC_013093.1 6226930 6228747 R KEGG: scl:sce1211 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; gamma-glutamyltransferase complement(6226930..6228747) Actinosynnema mirum DSM 43827 8329434 YP_003102900.1 CDS Amir_5233 NC_013093.1 6228957 6229259 D KEGG: hypothetical protein; hypothetical protein 6228957..6229259 Actinosynnema mirum DSM 43827 8329435 YP_003102901.1 CDS Amir_5234 NC_013093.1 6229267 6231264 R KEGG: bav:BAV3210 primosomal protein N'; Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein complement(6229267..6231264) Actinosynnema mirum DSM 43827 8329436 YP_003102902.1 CDS Amir_5235 NC_013093.1 6231334 6232536 R KEGG: bha:BH3300 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase complement(6231334..6232536) Actinosynnema mirum DSM 43827 8329437 YP_003102903.1 CDS Amir_5236 NC_013093.1 6232619 6233887 R KEGG: acp:A2cp1_1587 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase complement(6232619..6233887) Actinosynnema mirum DSM 43827 8329438 YP_003102904.1 CDS Amir_5237 NC_013093.1 6233884 6234162 R TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; KEGG: rma:Rmag_0405 DNA-directed RNA polymerase, omega subunit; DNA-directed RNA polymerase subunit omega complement(6233884..6234162) Actinosynnema mirum DSM 43827 8329439 YP_003102905.1 CDS Amir_5238 NC_013093.1 6234290 6234889 R KEGG: bcy:Bcer98_2523 guanylate kinase; TIGRFAM: guanylate kinase; PFAM: guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; guanylate kinase complement(6234290..6234889) Actinosynnema mirum DSM 43827 8329440 YP_003102906.1 CDS Amir_5239 NC_013093.1 6234886 6235203 R hypothetical protein complement(6234886..6235203) Actinosynnema mirum DSM 43827 8329441 YP_003102907.1 CDS Amir_5240 NC_013093.1 6235512 6236330 R TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mxa:MXAN_5910 orotidine 5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase complement(6235512..6236330) Actinosynnema mirum DSM 43827 8329442 YP_003102908.1 CDS Amir_5241 NC_013093.1 6236327 6239626 R TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: carbamoyl-phosphate synthase L chain ATP- binding; RimK domain protein ATP-grasp; MGS domain protein; ATP-grasp domain protein; carbamoyl-phosphate synthetase large chain oligomerisation; carbamoyl- phosphate synthetase large chain domain protein; KEGG: gur:Gura_1864 carbamoyl-phosphate synthase, large subunit; carbamoyl-phosphate synthase, large subunit complement(6236327..6239626) Actinosynnema mirum DSM 43827 8329443 YP_003102909.1 CDS Amir_5242 NC_013093.1 6239628 6240740 R KEGG: smt:Smal_1811 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; carbamoyl-phosphate synthase, small subunit complement(6239628..6240740) Actinosynnema mirum DSM 43827 8329444 YP_003102910.1 CDS Amir_5243 NC_013093.1 6240737 6241228 R hypothetical protein complement(6240737..6241228) Actinosynnema mirum DSM 43827 8329445 YP_003102911.1 CDS pyrC NC_013093.1 6241225 6242526 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(6241225..6242526) Actinosynnema mirum DSM 43827 8329446 YP_003102912.1 CDS Amir_5245 NC_013093.1 6242523 6243458 R TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: scl:sce3822 hypothetical protein; aspartate carbamoyltransferase complement(6242523..6243458) Actinosynnema mirum DSM 43827 8329447 YP_003102913.1 CDS Amir_5246 NC_013093.1 6243455 6244027 R PFAM: phosphoribosyltransferase; KEGG: gsu:GSU1270 pyrimidine regulatory protein pyrR; uracil phosphoribosyltransferase complement(6243455..6244027) Actinosynnema mirum DSM 43827 8329448 YP_003102914.1 CDS Amir_5247 NC_013093.1 6244286 6244774 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pzu:PHZ_c2067 transcriptional regulator, Cro/CI family; XRE family transcriptional regulator 6244286..6244774 Actinosynnema mirum DSM 43827 8329449 YP_003102915.1 CDS Amir_5248 NC_013093.1 6245175 6245594 R TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44; KEGG: mxa:MXAN_4761 transcription antitermination factor NusB; NusB antitermination factor complement(6245175..6245594) Actinosynnema mirum DSM 43827 8329450 YP_003102916.1 CDS Amir_5249 NC_013093.1 6245596 6246159 R TIGRFAM: translation elongation factor P; PFAM: Elongation factor KOW domain protein; Elongation factor P; Elongation factor P/YeiP protein; KEGG: bha:BH2799 elongation factor P; translation elongation factor P complement(6245596..6246159) Actinosynnema mirum DSM 43827 8329451 YP_003102917.1 CDS Amir_5250 NC_013093.1 6246215 6247312 R PFAM: peptidase M24; creatinase; KEGG: sus:Acid_7433 peptidase M24; peptidase M24 complement(6246215..6247312) Actinosynnema mirum DSM 43827 8329452 YP_003102918.1 CDS Amir_5251 NC_013093.1 6247785 6249296 R KEGG: mrd:Mrad2831_3019 hypothetical protein; hypothetical protein complement(6247785..6249296) Actinosynnema mirum DSM 43827 8329453 YP_003102919.1 CDS Amir_5252 NC_013093.1 6249782 6250222 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(6249782..6250222) Actinosynnema mirum DSM 43827 8329454 YP_003102920.1 CDS aroB NC_013093.1 6250219 6251325 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(6250219..6251325) Actinosynnema mirum DSM 43827 8329455 YP_003102921.1 CDS Amir_5254 NC_013093.1 6252277 6252792 R PFAM: shikimate kinase; KEGG: pen:PSEEN0334 shikimate kinase; shikimate kinase complement(6252277..6252792) Actinosynnema mirum DSM 43827 8329456 YP_003102922.1 CDS Amir_5255 NC_013093.1 6252789 6253988 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(6252789..6253988) Actinosynnema mirum DSM 43827 8329457 YP_003102923.1 CDS Amir_5256 NC_013093.1 6254941 6255525 R PFAM: peptidase A24A prepilin type IV; KEGG: hha:Hhal_2022 prepilin peptidase; peptidase A24A prepilin type IV complement(6254941..6255525) Actinosynnema mirum DSM 43827 8329458 YP_003102924.1 CDS Amir_5257 NC_013093.1 6255717 6256175 R TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: bsu:BSU39270 phosphotransferase system (PTS) beta-glucoside-specific enzyme IIBCA component; PTS system, glucose subfamily, IIA subunit complement(6255717..6256175) Actinosynnema mirum DSM 43827 8329459 YP_003102925.1 CDS Amir_5258 NC_013093.1 6256172 6256408 R PFAM: phosphotransferase system PTS EIIB protein; KEGG: esa:ESA_00528 hypothetical protein; phosphotransferase system PTS EIIB protein complement(6256172..6256408) Actinosynnema mirum DSM 43827 8329460 YP_003102926.1 CDS Amir_5259 NC_013093.1 6256582 6257346 D PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bha:BH0419 GntR family transcriptional regulator; GntR family transcriptional regulator 6256582..6257346 Actinosynnema mirum DSM 43827 8329461 YP_003102927.1 CDS Amir_5260 NC_013093.1 6257343 6258641 D PFAM: phosphotransferase system EIIC; KEGG: bha:BH0422 PTS system, N-acetylglucosamine- specific enzyme II, ABC component; Protein-N(pi)-phosphohistidine--sugar phosphotransferase 6257343..6258641 Actinosynnema mirum DSM 43827 8329462 YP_003102928.1 CDS Amir_5261 NC_013093.1 6258660 6258932 D TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: aeh:Mlg_2234 HPr family phosphocarrier protein; phosphotransferase system, phosphocarrier protein HPr 6258660..6258932 Actinosynnema mirum DSM 43827 8329463 YP_003102929.1 CDS aroE NC_013093.1 6259027 6259884 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(6259027..6259884) Actinosynnema mirum DSM 43827 8329464 YP_003102930.1 CDS Amir_5263 NC_013093.1 6259865 6261094 R PFAM: aminodeoxychorismate lyase; KEGG: gme:Gmet_3021 aminodeoxychorismate lyase; aminodeoxychorismate lyase complement(6259865..6261094) Actinosynnema mirum DSM 43827 8329465 YP_003102931.1 CDS Amir_5264 NC_013093.1 6261091 6261603 R PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; KEGG: bha:BH1269 hypothetical protein; Holliday junction resolvase YqgF complement(6261091..6261603) Actinosynnema mirum DSM 43827 8329466 YP_003102932.1 CDS alaS NC_013093.1 6261590 6264262 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(6261590..6264262) Actinosynnema mirum DSM 43827 8329467 YP_003102933.1 CDS Amir_5266 NC_013093.1 6264317 6264580 R hypothetical protein complement(6264317..6264580) Actinosynnema mirum DSM 43827 8329468 YP_003102934.1 CDS Amir_5267 NC_013093.1 6264577 6264984 R hypothetical protein complement(6264577..6264984) Actinosynnema mirum DSM 43827 8329469 YP_003102935.1 CDS Amir_5268 NC_013093.1 6265231 6265353 D hypothetical protein 6265231..6265353 Actinosynnema mirum DSM 43827 8329470 YP_003102936.1 CDS Amir_5269 NC_013093.1 6265354 6266541 D PFAM: cupin; SMART: transcription factor jumonji jmjC domain protein; KEGG: jan:Jann_0385 cupin 4; cupin 6265354..6266541 Actinosynnema mirum DSM 43827 8329471 YP_003102937.1 CDS Amir_5270 NC_013093.1 6266592 6267536 D PFAM: sucraseferredoxin; KEGG: hch:HCH_03459 hypothetical protein; sucraseferredoxin 6266592..6267536 Actinosynnema mirum DSM 43827 8329472 YP_003102938.1 CDS Amir_5271 NC_013093.1 6267852 6268616 R PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: sfu:Sfum_2834 methyltransferase type 12; type 12 methyltransferase complement(6267852..6268616) Actinosynnema mirum DSM 43827 8329473 YP_003102939.1 CDS Amir_5272 NC_013093.1 6268687 6270033 R PFAM: ATPase AAA; magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: gsu:GSU2067 recombination factor protein RarA; recombination factor protein RarA complement(6268687..6270033) Actinosynnema mirum DSM 43827 8329474 YP_003102940.1 CDS Amir_5273 NC_013093.1 6270146 6270784 D KEGG: hypothetical protein; K00876 uridine kinase; uridine kinase-like protein 6270146..6270784 Actinosynnema mirum DSM 43827 8329475 YP_003102941.1 CDS Amir_5274 NC_013093.1 6271178 6273661 D PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: scl:sce4364 ATP-dependent helicase; DEAD/DEAH box helicase domain-containing protein 6271178..6273661 Actinosynnema mirum DSM 43827 8329476 YP_003102942.1 CDS Amir_5275 NC_013093.1 6273904 6276873 D PFAM: transcriptional activator domain; TPR repeat- containing protein; NB-ARC domain protein; transcriptional regulator domain protein; SMART: ATPase AAA; hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator 6273904..6276873 Actinosynnema mirum DSM 43827 8329477 YP_003102943.1 CDS Amir_5276 NC_013093.1 6277215 6277832 R PFAM: transglycosylase domain protein; peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: ade:Adeh_2701 peptidoglycan-binding LysM; transglycosylase domain-containing protein complement(6277215..6277832) Actinosynnema mirum DSM 43827 8329478 YP_003102944.1 CDS Amir_5277 NC_013093.1 6278228 6278500 D hypothetical protein 6278228..6278500 Actinosynnema mirum DSM 43827 8329479 YP_003102945.1 CDS Amir_5278 NC_013093.1 6278537 6279382 D PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; KEGG: rpi:Rpic_1227 two component transcriptional regulator, LytTR family; LytTR family two component transcriptional regulator 6278537..6279382 Actinosynnema mirum DSM 43827 8329480 YP_003102946.1 CDS Amir_5279 NC_013093.1 6279379 6279813 D PFAM: protein of unknown function DUF485; hypothetical protein 6279379..6279813 Actinosynnema mirum DSM 43827 8329481 YP_003102947.1 CDS Amir_5280 NC_013093.1 6279810 6281531 D PFAM: Na+/solute symporter; KEGG: ade:Adeh_3696 SSS family solute/sodium (Na+) symporter; Na+/solute symporter 6279810..6281531 Actinosynnema mirum DSM 43827 8329482 YP_003102948.1 CDS Amir_5281 NC_013093.1 6281528 6282703 D PFAM: histidine kinase internal region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: gme:Gmet_2698 histidine kinase internal region; signal transduction histidine kinase LytS 6281528..6282703 Actinosynnema mirum DSM 43827 8329483 YP_003102949.1 CDS Amir_5282 NC_013093.1 6282803 6283177 R KEGG: rle:RL1216 hypothetical protein; hypothetical protein complement(6282803..6283177) Actinosynnema mirum DSM 43827 8329484 YP_003102950.1 CDS Amir_5283 NC_013093.1 6283261 6283815 D PFAM: regulatory protein TetR; KEGG: rlt:Rleg2_5162 transcriptional regulator, TetR family; TetR family transcriptional regulator 6283261..6283815 Actinosynnema mirum DSM 43827 8329485 YP_003102951.1 CDS Amir_5284 NC_013093.1 6283907 6284491 R KEGG: bvi:Bcep1808_7569 transposase and inactivated derivatives-like protein; hypothetical protein complement(6283907..6284491) Actinosynnema mirum DSM 43827 8329486 YP_003102952.1 CDS Amir_5285 NC_013093.1 6284674 6285519 D PFAM: metallophosphoesterase; KEGG: scl:sce5059 metallophosphoesterase; metallophosphoesterase 6284674..6285519 Actinosynnema mirum DSM 43827 8329487 YP_003102953.1 CDS Amir_5286 NC_013093.1 6285516 6286172 D PFAM: 4'-phosphopantetheinyl transferase; KEGG: gdi:GDI2832 phosphopantetheinyl transferase PptA; 4'-phosphopantetheinyl transferase 6285516..6286172 Actinosynnema mirum DSM 43827 8329488 YP_003102954.1 CDS Amir_5287 NC_013093.1 6286242 6287723 D KEGG: swd:Swoo_0692 CBS domain-containing protein; CBS domain-containing protein 6286242..6287723 Actinosynnema mirum DSM 43827 8329489 YP_003102955.1 CDS Amir_5288 NC_013093.1 6287965 6289797 D PFAM: hypothetical protein; KEGG: ecw:EcE24377A_3363 hypothetical protein; hypothetical protein 6287965..6289797 Actinosynnema mirum DSM 43827 8329490 YP_003102956.1 CDS Amir_5289 NC_013093.1 6290127 6290963 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: spe:Spro_3591 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase complement(6290127..6290963) Actinosynnema mirum DSM 43827 8329491 YP_003102957.1 CDS Amir_5290 NC_013093.1 6291107 6291490 D PFAM: helix-turn-helix HxlR type; KEGG: transcriptional regulator protein; HxlR family transcriptional regulator 6291107..6291490 Actinosynnema mirum DSM 43827 8329492 YP_003102958.1 CDS Amir_5291 NC_013093.1 6291487 6291816 R hypothetical protein complement(6291487..6291816) Actinosynnema mirum DSM 43827 8329493 YP_003102959.1 CDS Amir_5292 NC_013093.1 6292020 6292427 R hypothetical protein complement(6292020..6292427) Actinosynnema mirum DSM 43827 8329494 YP_003102960.1 CDS Amir_5293 NC_013093.1 6292427 6293101 R KEGG: xcv:XCV1426 hypothetical protein; hypothetical protein complement(6292427..6293101) Actinosynnema mirum DSM 43827 8329495 YP_003102961.1 CDS Amir_5294 NC_013093.1 6293171 6293743 R catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase complement(6293171..6293743) Actinosynnema mirum DSM 43827 8329496 YP_003102962.1 CDS Amir_5295 NC_013093.1 6293798 6294367 R PFAM: regulatory protein TetR; KEGG: mno:Mnod_1181 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(6293798..6294367) Actinosynnema mirum DSM 43827 8329497 YP_003102963.1 CDS Amir_5296 NC_013093.1 6294444 6295292 D PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: rlt:Rleg2_1533 methyltransferase type 12; type 11 methyltransferase 6294444..6295292 Actinosynnema mirum DSM 43827 8329498 YP_003102964.1 CDS Amir_5297 NC_013093.1 6296166 6297128 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: bxe:Bxe_C1266 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(6296166..6297128) Actinosynnema mirum DSM 43827 8329499 YP_003102965.1 CDS Amir_5298 NC_013093.1 6297234 6298163 D PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mmw:Mmwyl1_2496 helix-turn-helix domain- containing protein; AraC family transcriptional regulator 6297234..6298163 Actinosynnema mirum DSM 43827 8329500 YP_003102966.1 CDS Amir_5299 NC_013093.1 6298310 6299056 D hypothetical protein 6298310..6299056 Actinosynnema mirum DSM 43827 8329501 YP_003102967.1 CDS Amir_5300 NC_013093.1 6299047 6299460 D hypothetical protein 6299047..6299460 Actinosynnema mirum DSM 43827 8329502 YP_003102968.1 CDS Amir_5301 NC_013093.1 6299539 6300297 R KEGG: rpc:RPC_1516 hypothetical protein; hypothetical protein complement(6299539..6300297) Actinosynnema mirum DSM 43827 8329503 YP_003102969.1 CDS Amir_5302 NC_013093.1 6300294 6301490 R KEGG: Trpm4; transient receptor potential cation channel, subfamily M, member 4; K04979 transient receptor potential cation channel, subfamily M, member 4; hypothetical protein complement(6300294..6301490) Actinosynnema mirum DSM 43827 8329504 YP_003102970.1 CDS Amir_5303 NC_013093.1 6301664 6303055 D KEGG: xca:xccb100_0630 oxidoreductase; oxidoreductase 6301664..6303055 Actinosynnema mirum DSM 43827 8329505 YP_003102971.1 CDS Amir_5304 NC_013093.1 6303143 6306604 D SMART: ATPase AAA; KEGG: bbr:BB2829 hypothetical protein; ATPase AAA 6303143..6306604 Actinosynnema mirum DSM 43827 8329506 YP_003102972.1 CDS Amir_5305 NC_013093.1 6307215 6307934 D TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: predicted protein; LPXTG-motif cell wall anchor domain-containing protein 6307215..6307934 Actinosynnema mirum DSM 43827 8329507 YP_003102973.1 CDS Amir_5306 NC_013093.1 6308101 6309090 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: scl:sce9297 zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(6308101..6309090) Actinosynnema mirum DSM 43827 8329508 YP_003102974.1 CDS Amir_5307 NC_013093.1 6309087 6309890 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: gdi:GDI2636 transporter protein; ABC transporter inner membrane protein complement(6309087..6309890) Actinosynnema mirum DSM 43827 8329509 YP_003102975.1 CDS Amir_5308 NC_013093.1 6309887 6310771 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bam:Bamb_2642 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein complement(6309887..6310771) Actinosynnema mirum DSM 43827 8329510 YP_003102976.1 CDS Amir_5309 NC_013093.1 6310806 6312149 R PFAM: extracellular solute-binding protein family 1; KEGG: bac:BamMC406_2511 extracellular solute- binding protein; family 1 extracellular solute-binding protein complement(6310806..6312149) Actinosynnema mirum DSM 43827 8329511 YP_003102977.1 CDS Amir_5310 NC_013093.1 6312231 6312992 R PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: cak:Caul_0312 DeoR family transcriptional regulator; DeoR family transcriptional regulator complement(6312231..6312992) Actinosynnema mirum DSM 43827 8329512 YP_003102978.1 CDS Amir_5311 NC_013093.1 6313722 6314243 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: cvi:CV_1553 enoyl-CoA hydratase; Enoyl-CoA hydratase/isomerase complement(6313722..6314243) Actinosynnema mirum DSM 43827 8329513 YP_003102979.1 CDS Amir_5312 NC_013093.1 6314325 6314918 D hypothetical protein 6314325..6314918 Actinosynnema mirum DSM 43827 8329514 YP_003102980.1 CDS Amir_5313 NC_013093.1 6314998 6318039 D PFAM: lanthionine synthetase C family protein; KEGG: mxa:MXAN_6388 lanthionine synthetase C family protein; lanthionine synthetase C family protein 6314998..6318039 Actinosynnema mirum DSM 43827 8329515 YP_003102981.1 CDS Amir_5314 NC_013093.1 6318092 6318322 D KEGG: hypothetical protein; hypothetical protein 6318092..6318322 Actinosynnema mirum DSM 43827 8329516 YP_003102982.1 CDS Amir_5315 NC_013093.1 6319267 6322164 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: ade:Adeh_3289 SARP family transcriptional regulator; LuxR family transcriptional regulator 6319267..6322164 Actinosynnema mirum DSM 43827 8329517 YP_003102983.1 CDS Amir_5316 NC_013093.1 6322251 6322949 D PFAM: MOSC domain containing protein; KEGG: mex:Mext_4291 MOSC domain-containing protein; MOSC domain containing protein 6322251..6322949 Actinosynnema mirum DSM 43827 8329518 YP_003102984.1 CDS Amir_5317 NC_013093.1 6322971 6323810 R PFAM: aldo/keto reductase; KEGG: aba:Acid345_2253 aldo/keto reductase; aldo/keto reductase complement(6322971..6323810) Actinosynnema mirum DSM 43827 8329519 YP_003102985.1 CDS Amir_5318 NC_013093.1 6324006 6324995 D KEGG: rso:RS03172 signal peptide protein; hypothetical protein 6324006..6324995 Actinosynnema mirum DSM 43827 8329520 YP_003102986.1 CDS Amir_5320 NC_013093.1 6325289 6327316 R catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase complement(6325289..6327316) Actinosynnema mirum DSM 43827 8329522 YP_003102987.1 CDS Amir_5321 NC_013093.1 6327469 6328749 D PFAM: glycoside hydrolase family 16; Ricin B lectin; SMART: Ricin B lectin; KEGG: cja:CJA_2759 beta glucanase, , glu16F; glycoside hydrolase family protein 6327469..6328749 Actinosynnema mirum DSM 43827 8329523 YP_003102988.1 CDS Amir_5322 NC_013093.1 6328982 6329386 R KEGG: hypothetical protein; hypothetical protein complement(6328982..6329386) Actinosynnema mirum DSM 43827 8329524 YP_003102989.1 CDS Amir_5323 NC_013093.1 6329566 6332643 R PFAM: transcriptional activator domain; TPR repeat- containing protein; hypothetical protein; NB-ARC domain protein; transcriptional regulator domain protein; hypothetical protein; SMART: hypothetical protein; KEGG: scl:sce6858 hypothetical protein; SARP family transcriptional regulator complement(6329566..6332643) Actinosynnema mirum DSM 43827 8329525 YP_003102990.1 CDS Amir_5324 NC_013093.1 6332870 6334897 R PFAM: acyltransferase 3; KEGG: mes:Meso_0485 acyltransferase 3; acyltransferase 3 complement(6332870..6334897) Actinosynnema mirum DSM 43827 8329526 YP_003102991.1 CDS Amir_5325 NC_013093.1 6335295 6336191 R PFAM: protein of unknown function DUF75; KEGG: sfu:Sfum_3209 hypothetical protein; hypothetical protein complement(6335295..6336191) Actinosynnema mirum DSM 43827 8329527 YP_003102992.1 CDS Amir_5326 NC_013093.1 6336478 6338442 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: sat:SYN_01564 phospholipid-lipopolysaccharide ABC transporter; ABC transporter 6336478..6338442 Actinosynnema mirum DSM 43827 8329528 YP_003102993.1 CDS Amir_5327 NC_013093.1 6338502 6339098 D KEGG: mch:Mchl_4435 methyl-accepting chemotaxis sensory transducer; hypothetical protein 6338502..6339098 Actinosynnema mirum DSM 43827 8329529 YP_003102994.1 CDS Amir_5328 NC_013093.1 6339241 6340680 D KEGG: bxe:Bxe_B2117 CdaR family transcriptional regulator; PucR family transcriptional regulator 6339241..6340680 Actinosynnema mirum DSM 43827 8329530 YP_003102995.1 CDS Amir_5329 NC_013093.1 6340818 6341435 D KEGG: aba:Acid345_2313 hypothetical protein; hypothetical protein 6340818..6341435 Actinosynnema mirum DSM 43827 8329531 YP_003102996.1 CDS Amir_5330 NC_013093.1 6341614 6342186 R PFAM: regulatory protein TetR; KEGG: ade:Adeh_2298 TetR family transcriptional regulator; TetR family transcriptional regulator complement(6341614..6342186) Actinosynnema mirum DSM 43827 8329532 YP_003102997.1 CDS Amir_5331 NC_013093.1 6342287 6343165 D PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; dTDP-4-dehydrorhamnose reductase; KEGG: acp:A2cp1_1649 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 6342287..6343165 Actinosynnema mirum DSM 43827 8329533 YP_003102998.1 CDS Amir_5332 NC_013093.1 6343268 6344176 D PFAM: pseudouridine synthase; KEGG: pmy:Pmen_1453 pseudouridine synthase; pseudouridine synthase 6343268..6344176 Actinosynnema mirum DSM 43827 8329534 YP_003102999.1 CDS Amir_5333 NC_013093.1 6344234 6344854 R PFAM: protein of unknown function DUF305; KEGG: pag:PLES_26381 hypothetical protein; hypothetical protein complement(6344234..6344854) Actinosynnema mirum DSM 43827 8329535 YP_003103000.1 CDS Amir_5334 NC_013093.1 6344924 6345712 R PFAM: chitin-binding domain 3 protein; carbohydrate- binding family V/XII; SMART: carbohydrate-binding family V/XII; KEGG: hypothetical protein; chitin-binding domain 3 protein complement(6344924..6345712) Actinosynnema mirum DSM 43827 8329536 YP_003103001.1 CDS Amir_5335 NC_013093.1 6346362 6346919 D KEGG: glo:Glov_2382 alpha/beta hydrolase fold; hypothetical protein 6346362..6346919 Actinosynnema mirum DSM 43827 8329537 YP_003103002.1 CDS Amir_5336 NC_013093.1 6347070 6348176 R PFAM: glycoside hydrolase family 19; KEGG: cja:CJA_0996 chitinase, , chi19A; chitinase complement(6347070..6348176) Actinosynnema mirum DSM 43827 8329538 YP_003103003.1 CDS Amir_5337 NC_013093.1 6348544 6349017 R KEGG: hha:Hhal_2194 alcohol dehydrogenase, zinc- binding domain protein; hypothetical protein complement(6348544..6349017) Actinosynnema mirum DSM 43827 8329539 YP_003103004.1 CDS Amir_5338 NC_013093.1 6349014 6349259 R KEGG: mlo:mll2594 quinone oxidoreductase; quinone oxidoreductase complement(6349014..6349259) Actinosynnema mirum DSM 43827 8329540 YP_003103005.1 CDS Amir_5339 NC_013093.1 6349434 6352061 D PFAM: glycoside hydrolase family 9; cellulose- binding family II; glycoside hydrolase family 9 domain protein Ig domain protein; carbohydrate-binding CenC domain protein; SMART: cellulose-binding family II; KEGG: scl:sce2234 cellulase; glycoside hydrolase family protein 6349434..6352061 Actinosynnema mirum DSM 43827 8329541 YP_003103006.1 CDS Amir_5340 NC_013093.1 6352115 6352744 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: psa:PST_1446 oxidoreductase, short-chain dehydrogenase/reductase family; short-chain dehydrogenase/reductase SDR complement(6352115..6352744) Actinosynnema mirum DSM 43827 8329542 YP_003103007.1 CDS Amir_5341 NC_013093.1 6352953 6354005 D KEGG: sus:Acid_4466 beta-lactamase; hypothetical protein 6352953..6354005 Actinosynnema mirum DSM 43827 8329543 YP_003103008.1 CDS Amir_5342 NC_013093.1 6354255 6355676 D TIGRFAM: Dyp-type peroxidase family; KEGG: aba:Acid345_1379 hypothetical protein; Dyp-type peroxidase family 6354255..6355676 Actinosynnema mirum DSM 43827 8329544 YP_003103009.1 CDS Amir_5343 NC_013093.1 6356553 6357593 D KEGG: pzu:PHZ_c2158 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; LacI family transcriptional regulator 6356553..6357593 Actinosynnema mirum DSM 43827 8329545 YP_003103010.1 CDS Amir_5344 NC_013093.1 6357740 6359074 D PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: pde:Pden_3115 protein of unknown function DUF21; hypothetical protein 6357740..6359074 Actinosynnema mirum DSM 43827 8329546 YP_003103011.1 CDS Amir_5345 NC_013093.1 6359071 6360117 D PFAM: protein of unknown function DUF21; CBS domain containing protein; KEGG: hps:HPSH_07635 hypothetical protein; hypothetical protein 6359071..6360117 Actinosynnema mirum DSM 43827 8329547 YP_003103012.1 CDS Amir_5346 NC_013093.1 6360553 6361452 D hypothetical protein 6360553..6361452 Actinosynnema mirum DSM 43827 8329548 YP_003103013.1 CDS Amir_5347 NC_013093.1 6361708 6363498 D SMART: von Willebrand factor type A; KEGG: hypothetical protein; von Willebrand factor type A 6361708..6363498 Actinosynnema mirum DSM 43827 8329549 YP_003103014.1 CDS Amir_5349 NC_013093.1 6363847 6364035 D hypothetical protein 6363847..6364035 Actinosynnema mirum DSM 43827 8329551 YP_003103015.1 CDS Amir_5350 NC_013093.1 6364039 6364938 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: mlo:mlr0745 transcriptional regulator; ArsR family transcriptional regulator complement(6364039..6364938) Actinosynnema mirum DSM 43827 8329552 YP_003103016.1 CDS Amir_5351 NC_013093.1 6364996 6366201 D PFAM: major facilitator superfamily MFS_1; KEGG: sil:SPO1430 antibiotic efflux protein; major facilitator superfamily protein 6364996..6366201 Actinosynnema mirum DSM 43827 8329553 YP_003103017.1 CDS Amir_5352 NC_013093.1 6366280 6369168 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(6366280..6369168) Actinosynnema mirum DSM 43827 8329554 YP_003103018.1 CDS Amir_5353 NC_013093.1 6369652 6370218 R SMART: regulatory protein MerR; KEGG: afw:Anae109_4225 MerR family transcriptional regulator; MerR family transcriptional regulator complement(6369652..6370218) Actinosynnema mirum DSM 43827 8329555 YP_003103019.1 CDS Amir_5354 NC_013093.1 6370603 6371076 R PFAM: protein of unknown function DUF151; KEGG: dal:Dalk_2411 protein of unknown function DUF151; hypothetical protein complement(6370603..6371076) Actinosynnema mirum DSM 43827 8329556 YP_003103020.1 CDS Amir_5355 NC_013093.1 6371222 6372163 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: ade:Adeh_3310 zinc finger/thioredoxin; MerR family transcriptional regulator complement(6371222..6372163) Actinosynnema mirum DSM 43827 8329557 YP_003103021.1 CDS Amir_5356 NC_013093.1 6372197 6372649 R PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: scl:sce2902 GGDEF domain-containing protein; FHA domain containing protein complement(6372197..6372649) Actinosynnema mirum DSM 43827 8329558 YP_003103022.1 CDS Amir_5357 NC_013093.1 6372763 6373143 R TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; KEGG: ank:AnaeK_2621 glycine cleavage system H protein; glycine cleavage system H protein complement(6372763..6373143) Actinosynnema mirum DSM 43827 8329559 YP_003103023.1 CDS Amir_5358 NC_013093.1 6373202 6373813 R PFAM: CDP-alcohol phosphatidyltransferase; KEGG: tmz:Tmz1t_2031 CDP-diacylglycerol/glycerol-3- phosphate 3-phosphatidyltransferase; CDP-alcohol phosphatidyltransferase complement(6373202..6373813) Actinosynnema mirum DSM 43827 8329560 YP_003103024.1 CDS Amir_5359 NC_013093.1 6374316 6374522 R hypothetical protein complement(6374316..6374522) Actinosynnema mirum DSM 43827 8329561 YP_003103025.1 CDS Amir_5360 NC_013093.1 6374938 6375354 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mag:amb0333 anti-anti-sigma regulatory factor; anti-sigma-factor antagonist 6374938..6375354 Actinosynnema mirum DSM 43827 8329562 YP_003103026.1 CDS Amir_5361 NC_013093.1 6375305 6376102 R PFAM: ATP-binding region ATPase domain protein; KEGG: dvm:DvMF_0253 signal transduction histidine kinase; anti-sigma regulatory factor, serine/threonine protein kinase complement(6375305..6376102) Actinosynnema mirum DSM 43827 8329563 YP_003103027.1 CDS Amir_5362 NC_013093.1 6376261 6376698 D KEGG: bsu:BSU04720 serine-protein kinase RsbW; anti-sigma regulatory factor, serine/threonine protein kinase 6376261..6376698 Actinosynnema mirum DSM 43827 8329564 YP_003103028.1 CDS Amir_5363 NC_013093.1 6376695 6377501 D TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 4 domain protein; KEGG: bha:BH0529 RNA polymerase sigma factor SigB; SigB/F/G subfamily RNA polymerase sigma-28 subunit 6376695..6377501 Actinosynnema mirum DSM 43827 8329565 YP_003103029.1 CDS Amir_5364 NC_013093.1 6377686 6377985 D PFAM: transcription factor WhiB; transcription factor WhiB 6377686..6377985 Actinosynnema mirum DSM 43827 8329566 YP_003103030.1 CDS Amir_5365 NC_013093.1 6378158 6378817 R KEGG: mxa:MXAN_2497 hypothetical protein; hypothetical protein complement(6378158..6378817) Actinosynnema mirum DSM 43827 8329567 YP_003103031.1 CDS Amir_5366 NC_013093.1 6378900 6379853 D PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_0318 aldo/keto reductase; aldo/keto reductase 6378900..6379853 Actinosynnema mirum DSM 43827 8329568 YP_003103032.1 CDS Amir_5367 NC_013093.1 6379958 6380695 R KEGG: hypothetical protein; hypothetical protein complement(6379958..6380695) Actinosynnema mirum DSM 43827 8329569 YP_003103033.1 CDS Amir_5368 NC_013093.1 6381091 6382476 R KEGG: afw:Anae109_0266 response regulator receiver; hypothetical protein complement(6381091..6382476) Actinosynnema mirum DSM 43827 8329570 YP_003103034.1 CDS Amir_5369 NC_013093.1 6382614 6383333 R KEGG: ank:AnaeK_0242 Fe-S oxidoreductase; transmembrane anti-sigma factor complement(6382614..6383333) Actinosynnema mirum DSM 43827 8329571 YP_003103035.1 CDS Amir_5370 NC_013093.1 6383330 6383875 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpb:RPB_0486 RNA polymerase sigma factor RpoE; ECF subfamily RNA polymerase sigma-24 subunit complement(6383330..6383875) Actinosynnema mirum DSM 43827 8329572 YP_003103036.1 CDS Amir_5371 NC_013093.1 6384084 6384995 R KEGG: hypothetical protein; hypothetical protein complement(6384084..6384995) Actinosynnema mirum DSM 43827 8329573 YP_003103037.1 CDS Amir_5372 NC_013093.1 6385160 6385462 D PFAM: transcriptional regulator PadR family protein; KEGG: rpt:Rpal_2803 transcriptional regulator, PadR- like family; PadR family transcriptional regulator 6385160..6385462 Actinosynnema mirum DSM 43827 8329574 YP_003103038.1 CDS Amir_5373 NC_013093.1 6385476 6386459 R PFAM: Radical SAM domain protein; KEGG: sat:SYN_02268 radical SAM superfamily protein; Radical SAM domain-containing protein complement(6385476..6386459) Actinosynnema mirum DSM 43827 8329575 YP_003103039.1 CDS Amir_5374 NC_013093.1 6386659 6387315 D PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: oca:OCAR_4624 signal transduction histidine kinase containing PAS/PAC sensor domain; histidine kinase 6386659..6387315 Actinosynnema mirum DSM 43827 8329576 YP_003103040.1 CDS Amir_5375 NC_013093.1 6387312 6387968 D PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: bcr:BCAH187_A1601 DNA-binding response regulator; LuxR family transcriptional regulator 6387312..6387968 Actinosynnema mirum DSM 43827 8329577 YP_003103041.1 CDS Amir_5376 NC_013093.1 6388249 6388890 D PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: bcy:Bcer98_1160 two component LuxR family transcriptional regulator; LuxR family transcriptional regulator 6388249..6388890 Actinosynnema mirum DSM 43827 8329578 YP_003103042.1 CDS Amir_5377 NC_013093.1 6388993 6390333 R KEGG: mucin-associated surface protein (MASP); hypothetical protein complement(6388993..6390333) Actinosynnema mirum DSM 43827 8329579 YP_003103043.1 CDS Amir_5378 NC_013093.1 6390443 6393643 R PFAM: hypothetical protein; KEGG: hypothetical protein; hypothetical protein complement(6390443..6393643) Actinosynnema mirum DSM 43827 8329580 YP_003103044.1 CDS Amir_5379 NC_013093.1 6393676 6394797 R KEGG: mrd:Mrad2831_3727 translation initiation factor IF-2; FHA domain containing protein complement(6393676..6394797) Actinosynnema mirum DSM 43827 8329581 YP_003103045.1 CDS Amir_5380 NC_013093.1 6394794 6395333 R TIGRFAM: phage tail protein; KEGG: gsu:GSU0989 NHL repeat-containing protein; phage tail protein complement(6394794..6395333) Actinosynnema mirum DSM 43827 8329582 YP_003103046.1 CDS Amir_5381 NC_013093.1 6395330 6397264 R KEGG: gsu:GSU0988 hypothetical protein; hypothetical protein complement(6395330..6397264) Actinosynnema mirum DSM 43827 8329583 YP_003103047.1 CDS Amir_5382 NC_013093.1 6397264 6397671 R PFAM: GPW/gp25 family protein; KEGG: gsu:GSU0986 tail lysozyme; GPW/gp25 family protein complement(6397264..6397671) Actinosynnema mirum DSM 43827 8329584 YP_003103048.1 CDS Amir_5383 NC_013093.1 6397674 6397955 R PFAM: hypothetical protein; KEGG: dar:Daro_3608 PaaR; hypothetical protein complement(6397674..6397955) Actinosynnema mirum DSM 43827 8329585 YP_003103049.1 CDS Amir_5384 NC_013093.1 6398003 6399811 R TIGRFAM: Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: dsh:Dshi_2462 rhs element Vgr protein; Rhs element Vgr protein complement(6398003..6399811) Actinosynnema mirum DSM 43827 8329586 YP_003103050.1 CDS Amir_5385 NC_013093.1 6399804 6400559 R PFAM: peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: sde:Sde_1041 hypothetical protein; peptidoglycan-binding LysM complement(6399804..6400559) Actinosynnema mirum DSM 43827 8329587 YP_003103051.1 CDS Amir_5386 NC_013093.1 6400564 6400995 R TIGRFAM: conserved hypothetical protein; KEGG: noc:Noc_1873 phage tail region protein; hypothetical protein complement(6400564..6400995) Actinosynnema mirum DSM 43827 8329588 YP_003103052.1 CDS Amir_5387 NC_013093.1 6401077 6403479 R KEGG: NACA, TEBP; nascent polypeptide-associated complex alpha subunit; hypothetical protein complement(6401077..6403479) Actinosynnema mirum DSM 43827 8329589 YP_003103053.1 CDS Amir_5388 NC_013093.1 6403486 6403632 R KEGG: mlo:msr6553 hypothetical protein; hypothetical protein complement(6403486..6403632) Actinosynnema mirum DSM 43827 8329590 YP_003103054.1 CDS Amir_5389 NC_013093.1 6403629 6404042 R KEGG: gsu:GSU0977 hypothetical protein; hypothetical protein complement(6403629..6404042) Actinosynnema mirum DSM 43827 8329591 YP_003103055.1 CDS Amir_5390 NC_013093.1 6404042 6404485 R TIGRFAM: conserved hypothetical protein; KEGG: gsu:GSU0976 hypothetical protein; hypothetical protein complement(6404042..6404485) Actinosynnema mirum DSM 43827 8329592 YP_003103056.1 CDS Amir_5391 NC_013093.1 6404500 6406044 R PFAM: tail sheath protein; KEGG: mlo:mlr6548 hypothetical protein; tail sheath protein complement(6404500..6406044) Actinosynnema mirum DSM 43827 8329593 YP_003103057.1 CDS Amir_5392 NC_013093.1 6406289 6407020 R KEGG: nha:Nham_0826 hypothetical protein; hypothetical protein complement(6406289..6407020) Actinosynnema mirum DSM 43827 8329594 YP_003103058.1 CDS Amir_5393 NC_013093.1 6407067 6409115 R PFAM: ATPase AAA; SMART: ATPase AAA; KEGG: gsu:GSU0972 AAA family ATPase; ATPase AAA complement(6407067..6409115) Actinosynnema mirum DSM 43827 8329595 YP_003103059.1 CDS Amir_5394 NC_013093.1 6409112 6409699 R KEGG: noc:Noc_1875 hypothetical protein; hypothetical protein complement(6409112..6409699) Actinosynnema mirum DSM 43827 8329596 YP_003103060.1 CDS Amir_5395 NC_013093.1 6410006 6410854 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 6410006..6410854 Actinosynnema mirum DSM 43827 8329597 YP_003103061.1 CDS Amir_5396 NC_013093.1 6410851 6411051 D PFAM: protein of unknown function DUF397; hypothetical protein 6410851..6411051 Actinosynnema mirum DSM 43827 8329598 YP_003103062.1 CDS Amir_5397 NC_013093.1 6411057 6414092 R KEGG: scl:sce3623 hypothetical protein; hypothetical protein complement(6411057..6414092) Actinosynnema mirum DSM 43827 8329599 YP_003103063.1 CDS Amir_5398 NC_013093.1 6414473 6414841 D hypothetical protein 6414473..6414841 Actinosynnema mirum DSM 43827 8329600 YP_003103064.1 CDS Amir_5399 NC_013093.1 6414838 6415569 D TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 3 domain protein; KEGG: bha:BH0529 RNA polymerase sigma factor SigB; SigB/F/G subfamily RNA polymerase sigma-28 subunit 6414838..6415569 Actinosynnema mirum DSM 43827 8329601 YP_003103065.1 CDS Amir_5400 NC_013093.1 6415585 6416061 D KEGG: mpt:Mpe_A0228 hypothetical protein; hypothetical protein 6415585..6416061 Actinosynnema mirum DSM 43827 8329602 YP_003103066.1 CDS Amir_5401 NC_013093.1 6416153 6417079 D KEGG: mca:MCA0157 hypothetical protein; hypothetical protein 6416153..6417079 Actinosynnema mirum DSM 43827 8329603 YP_003103067.1 CDS Amir_5402 NC_013093.1 6417303 6418394 D PFAM: glutamate--cysteine ligase GCS2; KEGG: sus:Acid_3926 carboxylate-amine ligase; glutamate--cysteine ligase GCS2 6417303..6418394 Actinosynnema mirum DSM 43827 8329604 YP_003103068.1 CDS Amir_5403 NC_013093.1 6418455 6418811 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist; anti-sigma-factor antagonist 6418455..6418811 Actinosynnema mirum DSM 43827 8329605 YP_003103069.1 CDS Amir_5404 NC_013093.1 6419020 6419364 R hypothetical protein complement(6419020..6419364) Actinosynnema mirum DSM 43827 8329606 YP_003103070.1 CDS Amir_5405 NC_013093.1 6419495 6419938 R KEGG: rru:Rru_A3720 polysaccharide biosynthesis protein; hypothetical protein complement(6419495..6419938) Actinosynnema mirum DSM 43827 8329607 YP_003103071.1 CDS Amir_5406 NC_013093.1 6419935 6420552 R PFAM: ThiJ/PfpI domain protein; KEGG: bca:BCE_3203 ThiJ/PfpI family protein; ThiJ/PfpI domain-containing protein complement(6419935..6420552) Actinosynnema mirum DSM 43827 8329608 YP_003103072.1 CDS Amir_5407 NC_013093.1 6420660 6421601 D PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce6302 AraC family transcriptional regulator; AraC family transcriptional regulator 6420660..6421601 Actinosynnema mirum DSM 43827 8329609 YP_003103073.1 CDS Amir_5408 NC_013093.1 6421844 6423712 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_3338 serine/threonine protein kinase; serine/threonine protein kinase 6421844..6423712 Actinosynnema mirum DSM 43827 8329610 YP_003103074.1 CDS Amir_5409 NC_013093.1 6423709 6424185 R PFAM: CMP/dCMP deaminase zinc-binding; KEGG: smt:Smal_3461 CMP/dCMP deaminase zinc-binding; zinc-binding CMP/dCMP deaminase complement(6423709..6424185) Actinosynnema mirum DSM 43827 8329611 YP_003103075.1 CDS Amir_5410 NC_013093.1 6424241 6424756 R KEGG: ade:Adeh_3063 VCBS; hypothetical protein complement(6424241..6424756) Actinosynnema mirum DSM 43827 8329612 YP_003103076.1 CDS Amir_5411 NC_013093.1 6424892 6427513 R PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: sus:Acid_3454 tetratricopeptide TPR_4; hypothetical protein complement(6424892..6427513) Actinosynnema mirum DSM 43827 8329613 YP_003103077.1 CDS Amir_5412 NC_013093.1 6427591 6428805 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: ade:Adeh_0234 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 6427591..6428805 Actinosynnema mirum DSM 43827 8329614 YP_003103078.1 CDS Amir_5413 NC_013093.1 6428968 6429627 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: sus:Acid_3455 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 6428968..6429627 Actinosynnema mirum DSM 43827 8329615 YP_003103079.1 CDS Amir_5414 NC_013093.1 6429611 6430048 D hypothetical protein 6429611..6430048 Actinosynnema mirum DSM 43827 8329616 YP_003103080.1 CDS Amir_5415 NC_013093.1 6430567 6432522 D KEGG: azo:azo0950 GGEF/EAL/PAS/PAC-domain- containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat- containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 6430567..6432522 Actinosynnema mirum DSM 43827 8329617 YP_003103081.1 CDS Amir_5416 NC_013093.1 6432628 6433215 R PFAM: protein of unknown function ATP binding; Miro domain protein; KEGG: dac:Daci_0776 protein of unknown function ATP binding; hypothetical protein complement(6432628..6433215) Actinosynnema mirum DSM 43827 8329618 YP_003103082.1 CDS Amir_5417 NC_013093.1 6433254 6433676 R PFAM: Roadblock/LC7 family protein; KEGG: pna:Pnap_2813 roadblock/LC7 family protein; Roadblock/LC7 family protein complement(6433254..6433676) Actinosynnema mirum DSM 43827 8329619 YP_003103083.1 CDS Amir_5418 NC_013093.1 6433673 6436855 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: dvm:DvMF_1114 methyl-accepting chemotaxis sensory transducer; sensor with HAMP domain complement(6433673..6436855) Actinosynnema mirum DSM 43827 8329620 YP_003103084.1 CDS Amir_5419 NC_013093.1 6437119 6438156 R PFAM: NMT1/THI5 like domain protein; KEGG: bbt:BBta_5981 ABC transporter substrate- binding protein; NMT1/THI5 like domain-containing protein complement(6437119..6438156) Actinosynnema mirum DSM 43827 8329621 YP_003103085.1 CDS Amir_5420 NC_013093.1 6438347 6439549 D catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 6438347..6439549 Actinosynnema mirum DSM 43827 8329622 YP_003103086.1 CDS Amir_5421 NC_013093.1 6440358 6441242 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ABC transporter; ABC transporter complement(6440358..6441242) Actinosynnema mirum DSM 43827 8329623 YP_003103087.1 CDS Amir_5422 NC_013093.1 6441244 6442053 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ABC transporter, permease protein; ABC transporter inner membrane protein complement(6441244..6442053) Actinosynnema mirum DSM 43827 8329624 YP_003103088.1 CDS Amir_5423 NC_013093.1 6442050 6442946 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_1369 ABC transporter membrane protein; ABC transporter inner membrane protein complement(6442050..6442946) Actinosynnema mirum DSM 43827 8329625 YP_003103089.1 CDS Amir_5424 NC_013093.1 6442998 6443234 R hypothetical protein complement(6442998..6443234) Actinosynnema mirum DSM 43827 8329626 YP_003103090.1 CDS Amir_5425 NC_013093.1 6443568 6444308 R PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: sat:SYN_02856 RNA pseudouridylate synthase S4 domain-containing protein; pseudouridine synthase complement(6443568..6444308) Actinosynnema mirum DSM 43827 8329627 YP_003103091.1 CDS Amir_5426 NC_013093.1 6444301 6444882 R TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: sus:Acid_6490 condensin subunit ScpB; chromosome segregation and condensation protein ScpB complement(6444301..6444882) Actinosynnema mirum DSM 43827 8329628 YP_003103092.1 CDS Amir_5427 NC_013093.1 6444879 6445814 R PFAM: chromosome segregation and condensation protein ScpA; KEGG: mxa:MXAN_3841 segregation and condensation protein A; chromosome segregation and condensation protein ScpA complement(6444879..6445814) Actinosynnema mirum DSM 43827 8329629 YP_003103093.1 CDS Amir_5428 NC_013093.1 6445811 6446380 R KEGG: similar to Williams syndrome transcription factor; hypothetical protein complement(6445811..6446380) Actinosynnema mirum DSM 43827 8329630 YP_003103094.1 CDS Amir_5429 NC_013093.1 6446377 6447345 R PFAM: cobyrinic acid ac-diamide synthase; KEGG: bcb:BCB4264_A5607 sporulation initiation inhibitor protein Soj; cobyrinic acid ac-diamide synthase complement(6446377..6447345) Actinosynnema mirum DSM 43827 8329631 YP_003103095.1 CDS Amir_5430 NC_013093.1 6447438 6447770 R PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bca:BCE_2079 ArsR family transcriptional regulator; ArsR family transcriptional regulator complement(6447438..6447770) Actinosynnema mirum DSM 43827 8329632 YP_003103096.1 CDS Amir_5431 NC_013093.1 6447935 6448834 R TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: acp:A2cp1_2258 tyrosine recombinase XerD; tyrosine recombinase XerD complement(6447935..6448834) Actinosynnema mirum DSM 43827 8329633 YP_003103097.1 CDS Amir_5432 NC_013093.1 6448917 6449501 D PFAM: protein of unknown function DUF1707; TM2 domain containing protein?; KEGG: scl:sce7607 TM2 domain-containing protein; hypothetical protein 6448917..6449501 Actinosynnema mirum DSM 43827 8329634 YP_003103098.1 CDS Amir_5433 NC_013093.1 6449649 6450074 R KEGG: pca:Pcar_0371 hypothetical protein; hypothetical protein complement(6449649..6450074) Actinosynnema mirum DSM 43827 8329635 YP_003103099.1 CDS Amir_5434 NC_013093.1 6450314 6450955 R PFAM: NUDIX hydrolase; KEGG: dol:Dole_1905 NUDIX hydrolase; NUDIX hydrolase complement(6450314..6450955) Actinosynnema mirum DSM 43827 8329636 YP_003103100.1 CDS pyrG NC_013093.1 6450997 6452766 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(6450997..6452766) Actinosynnema mirum DSM 43827 8329637 YP_003103101.1 CDS Amir_5436 NC_013093.1 6452963 6453889 R KEGG: acp:A2cp1_3214 PE-PGRS family protein; hypothetical protein complement(6452963..6453889) Actinosynnema mirum DSM 43827 8329638 YP_003103102.1 CDS Amir_5437 NC_013093.1 6453895 6455079 R KEGG: bha:BH2771 hypothetical protein; membrane-anchored protein complement(6453895..6455079) Actinosynnema mirum DSM 43827 8329639 YP_003103103.1 CDS Amir_5438 NC_013093.1 6455221 6456480 R hypothetical protein complement(6455221..6456480) Actinosynnema mirum DSM 43827 8329640 YP_003103104.1 CDS Amir_5439 NC_013093.1 6456790 6458568 R TIGRFAM: DNA repair protein RecN; PFAM: hypothetical protein; KEGG: acp:A2cp1_0769 DNA repair protein RecN; DNA repair protein RecN complement(6456790..6458568) Actinosynnema mirum DSM 43827 8329641 YP_003103105.1 CDS Amir_5440 NC_013093.1 6458607 6459509 R PFAM: ATP-NAD/AcoX kinase; KEGG: ATP-NAD/AcoX kinase; K00858 NAD+ kinase; NAD(+) kinase complement(6458607..6459509) Actinosynnema mirum DSM 43827 8329642 YP_003103106.1 CDS Amir_5441 NC_013093.1 6459506 6460312 R KEGG: acp:A2cp1_1226 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; hemolysin A complement(6459506..6460312) Actinosynnema mirum DSM 43827 8329643 YP_003103107.1 CDS Amir_5442 NC_013093.1 6460319 6460492 R hypothetical protein complement(6460319..6460492) Actinosynnema mirum DSM 43827 8329644 YP_003103108.1 CDS Amir_5443 NC_013093.1 6460489 6461283 R TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bat:BAS4827 phosphatase; HAD superfamily hydrolase complement(6460489..6461283) Actinosynnema mirum DSM 43827 8329645 YP_003103109.1 CDS Amir_5444 NC_013093.1 6461835 6464591 R KEGG: dvu:DVU0907 hypothetical protein; hypothetical protein complement(6461835..6464591) Actinosynnema mirum DSM 43827 8329646 YP_003103110.1 CDS Amir_5445 NC_013093.1 6470460 6471743 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(6470460..6471743) Actinosynnema mirum DSM 43827 8329651 YP_003103111.1 CDS Amir_5446 NC_013093.1 6471778 6473502 R hypothetical protein complement(6471778..6473502) Actinosynnema mirum DSM 43827 8329652 YP_003103112.1 CDS Amir_5447 NC_013093.1 6473611 6474132 D PFAM: calcium-binding EF-hand-containing protein; SMART: calcium-binding EF-hand-containing protein; KEGG: Scp2; Sarcoplasmic calcium-binding protein 2; signal transduction protein with EFhand domain 6473611..6474132 Actinosynnema mirum DSM 43827 8329653 YP_003103113.1 CDS Amir_5448 NC_013093.1 6474160 6474789 R TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); KEGG: bmu:Bmul_0540 3-methyladenine DNA glycosylase; DNA-3-methyladenine glycosylase complement(6474160..6474789) Actinosynnema mirum DSM 43827 8329654 YP_003103114.1 CDS Amir_5449 NC_013093.1 6474773 6476164 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(6474773..6476164) Actinosynnema mirum DSM 43827 8329655 YP_003103115.1 CDS Amir_5450 NC_013093.1 6476259 6477206 R PFAM: argininosuccinate synthase; KEGG: bha:BH3187 argininosuccinate synthase; Argininosuccinate synthase complement(6476259..6477206) Actinosynnema mirum DSM 43827 8329656 YP_003103116.1 CDS Amir_5451 NC_013093.1 6477709 6478203 R TIGRFAM: arginine repressor; PFAM: arginine repressor; KEGG: afw:Anae109_0631 arginine repressor, ArgR; arginine repressor, ArgR complement(6477709..6478203) Actinosynnema mirum DSM 43827 8329657 YP_003103117.1 CDS Amir_5452 NC_013093.1 6478200 6479132 R TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: afr:AFE_0405 ornithine carbamoyltransferase; ornithine carbamoyltransferase complement(6478200..6479132) Actinosynnema mirum DSM 43827 8329658 YP_003103118.1 CDS argD NC_013093.1 6479138 6480301 R catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase complement(6479138..6480301) Actinosynnema mirum DSM 43827 8329659 YP_003103119.1 CDS Amir_5454 NC_013093.1 6480298 6481200 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(6480298..6481200) Actinosynnema mirum DSM 43827 8329660 YP_003103120.1 CDS argJ NC_013093.1 6481197 6482369 R bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein complement(6481197..6482369) Actinosynnema mirum DSM 43827 8329661 YP_003103121.1 CDS argC NC_013093.1 6482366 6483388 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(6482366..6483388) Actinosynnema mirum DSM 43827 8329662 YP_003103122.1 CDS Amir_5457 NC_013093.1 6483447 6484394 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: scl:sce1535 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein complement(6483447..6484394) Actinosynnema mirum DSM 43827 8329663 YP_003103123.1 CDS Amir_5459 NC_013093.1 6484733 6485830 D PFAM: transposase IS4 family protein; KEGG: sbc:SbBS512_A0291 transposase (IS4 family); transposase IS4 family protein 6484733..6485830 Actinosynnema mirum DSM 43827 8329665 YP_003103124.1 CDS Amir_5460 NC_013093.1 6486006 6486245 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: mmr:Mmar10_0512 XRE family transcriptional regulator; XRE family transcriptional regulator complement(6486006..6486245) Actinosynnema mirum DSM 43827 8329666 YP_003103125.1 CDS Amir_5461 NC_013093.1 6486239 6486682 R KEGG: cak:Caul_3518 hypothetical protein; hypothetical protein complement(6486239..6486682) Actinosynnema mirum DSM 43827 8329667 YP_003103126.1 CDS Amir_5462 NC_013093.1 6486787 6488202 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(6486787..6488202) Actinosynnema mirum DSM 43827 8329668 YP_003103127.1 CDS Amir_5463 NC_013093.1 6488290 6488787 R hypothetical protein complement(6488290..6488787) Actinosynnema mirum DSM 43827 8329669 YP_003103128.1 CDS Amir_5464 NC_013093.1 6489099 6491576 R KEGG: pca:Pcar_1423 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; phenylalanyl-tRNA synthetase subunit beta complement(6489099..6491576) Actinosynnema mirum DSM 43827 8329670 YP_003103129.1 CDS Amir_5465 NC_013093.1 6491580 6492647 R TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: cja:CJA_2526 phenylalanyl-tRNA synthetase, alpha subunit; phenylalanyl-tRNA synthetase subunit alpha complement(6491580..6492647) Actinosynnema mirum DSM 43827 8329671 YP_003103130.1 CDS Amir_5466 NC_013093.1 6492830 6494587 D PFAM: ATP-binding region ATPase domain protein; KEGG: mxa:MXAN_1393 ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; HSP90 family protein 6492830..6494587 Actinosynnema mirum DSM 43827 8329672 YP_003103131.1 CDS Amir_5467 NC_013093.1 6494601 6497432 D PFAM: hypothetical protein; hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: mxa:MXAN_1392 hypothetical protein; hypothetical protein 6494601..6497432 Actinosynnema mirum DSM 43827 8329673 YP_003103132.1 CDS Amir_5468 NC_013093.1 6497572 6498243 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sus:Acid_5477 two component transcriptional regulator; winged helix family two component transcriptional regulator 6497572..6498243 Actinosynnema mirum DSM 43827 8329674 YP_003103133.1 CDS Amir_5469 NC_013093.1 6498240 6499610 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: psa:PST_4043 sensor histidine kinase TctE; histidine kinase 6498240..6499610 Actinosynnema mirum DSM 43827 8329675 YP_003103134.1 CDS Amir_5470 NC_013093.1 6499607 6500455 R PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: ret:RHE_CH00393 rRNA methylase; tRNA/rRNA methyltransferase SpoU complement(6499607..6500455) Actinosynnema mirum DSM 43827 8329676 YP_003103135.1 CDS Amir_5471 NC_013093.1 6500455 6500844 R TIGRFAM: ribosomal protein L20; PFAM: ribosomal protein L20; KEGG: pfo:Pfl01_1934 50S ribosomal protein L20; 50S ribosomal protein L20 complement(6500455..6500844) Actinosynnema mirum DSM 43827 8329677 YP_003103136.1 CDS rpmI NC_013093.1 6500906 6501100 R TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: aba:Acid345_0714 LSU ribosomal protein L35P; 50S ribosomal protein L35 complement(6500906..6501100) Actinosynnema mirum DSM 43827 8329678 YP_003103137.1 CDS Amir_5473 NC_013093.1 6501185 6501799 R TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3; KEGG: ftm:FTM_1017 translation initiation factor IF- 3; translation initiation factor IF-3 complement(6501185..6501799) Actinosynnema mirum DSM 43827 8329679 YP_003103138.1 CDS Amir_5474 NC_013093.1 6502081 6502422 D hypothetical protein 6502081..6502422 Actinosynnema mirum DSM 43827 8329680 YP_003103139.1 CDS Amir_5475 NC_013093.1 6502580 6503233 R hypothetical protein complement(6502580..6503233) Actinosynnema mirum DSM 43827 8329681 YP_003103140.1 CDS Amir_5476 NC_013093.1 6503436 6505721 D PFAM: helix-turn-helix domain protein; NB-ARC domain protein; SMART: helix-turn-helix domain protein; ATPase AAA; KEGG: scl:sce5225 protein kinase; XRE family transcriptional regulator 6503436..6505721 Actinosynnema mirum DSM 43827 8329682 YP_003103141.1 CDS Amir_5477 NC_013093.1 6505946 6506332 R TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: mmw:Mmwyl1_4387 endoribonuclease L- PSP; endoribonuclease L-PSP complement(6505946..6506332) Actinosynnema mirum DSM 43827 8329683 YP_003103142.1 CDS Amir_5478 NC_013093.1 6506349 6507098 R PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: bha:BH2137 IclR family transcriptional regulator; IclR family transcriptional regulator complement(6506349..6507098) Actinosynnema mirum DSM 43827 8329684 YP_003103143.1 CDS Amir_5479 NC_013093.1 6507095 6508060 R PFAM: PfkB domain protein; KEGG: bha:BH3724 2-keto-3-deoxygluconate kinase; PfkB domain-containing protein complement(6507095..6508060) Actinosynnema mirum DSM 43827 8329685 YP_003103144.1 CDS Amir_5480 NC_013093.1 6508172 6509461 D PFAM: alanine racemase domain protein; KEGG: lch:Lcho_0086 D-serine deaminase; alanine racemase domain-containing protein 6508172..6509461 Actinosynnema mirum DSM 43827 8329686 YP_003103145.1 CDS Amir_5481 NC_013093.1 6509522 6511111 D PFAM: Amidohydrolase 3; D-aminoacylase domain protein; amidohydrolase; KEGG: hypothetical protein; N-acyl-D-amino-acid deacylase 6509522..6511111 Actinosynnema mirum DSM 43827 8329687 YP_003103146.1 CDS Amir_5482 NC_013093.1 6511108 6512502 D TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: oan:Oant_4271 gluconate transporter; gluconate transporter 6511108..6512502 Actinosynnema mirum DSM 43827 8329688 YP_003103147.1 CDS uvrA NC_013093.1 6512671 6515535 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(6512671..6515535) Actinosynnema mirum DSM 43827 8329689 YP_003103148.1 CDS Amir_5484 NC_013093.1 6515834 6516553 D in Corynebacterium glutamicum this enzyme catalyzes the conversion of maleylpyruvate into fumarylpyruvate in a glutathione-independent gentisate pathway; dependent on mycothiol; mycothiol-dependent maleylpyruvate isomerase 6515834..6516553 Actinosynnema mirum DSM 43827 8329690 YP_003103149.1 CDS Amir_5485 NC_013093.1 6516406 6517590 R PFAM: acyltransferase 3; KEGG: maq:Maqu_3475 acyltransferase 3; acyltransferase 3 complement(6516406..6517590) Actinosynnema mirum DSM 43827 8329691 YP_003103150.1 CDS Amir_5486 NC_013093.1 6517722 6518399 D PFAM: beta-lactamase domain protein; KEGG: gme:Gmet_2674 beta-lactamase-like; beta-lactamase domain-containing protein 6517722..6518399 Actinosynnema mirum DSM 43827 8329692 YP_003103151.1 CDS Amir_5487 NC_013093.1 6519162 6520460 R hypothetical protein complement(6519162..6520460) Actinosynnema mirum DSM 43827 8329693 YP_003103152.1 CDS Amir_5488 NC_013093.1 6521183 6521437 D hypothetical protein 6521183..6521437 Actinosynnema mirum DSM 43827 8329694 YP_003103153.1 CDS Amir_5489 NC_013093.1 6522106 6522792 R KEGG: hypothetical protein LOC762973; hypothetical protein complement(6522106..6522792) Actinosynnema mirum DSM 43827 8329695 YP_003103154.1 CDS Amir_5490 NC_013093.1 6522890 6524023 R PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein; GntR family transcriptional regulator complement(6522890..6524023) Actinosynnema mirum DSM 43827 8329696 YP_003103155.1 CDS Amir_5491 NC_013093.1 6524354 6524653 D PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bpt:Bpet3500 ArsR family transcriptional regulator; ArsR family transcriptional regulator 6524354..6524653 Actinosynnema mirum DSM 43827 8329697 YP_003103156.1 CDS Amir_5492 NC_013093.1 6524650 6525540 D PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: ank:AnaeK_2658 activator of HSP90 ATPase 1 family protein; Activator of Hsp90 ATPase 1 family protein 6524650..6525540 Actinosynnema mirum DSM 43827 8329698 YP_003103157.1 CDS Amir_5493 NC_013093.1 6525678 6526652 R KEGG: hypothetical protein; hypothetical protein complement(6525678..6526652) Actinosynnema mirum DSM 43827 8329699 YP_003103158.1 CDS Amir_5494 NC_013093.1 6526872 6527306 D PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: cti:RALTA_B0884 transcriptional regulator, AraC family, isolated domain; AraC family transcriptional regulator 6526872..6527306 Actinosynnema mirum DSM 43827 8329700 YP_003103159.1 CDS Amir_5495 NC_013093.1 6527303 6527713 D PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cti:RALTA_B0885 lyase; glyoxalase/bleomycin resistance protein/dioxygenase 6527303..6527713 Actinosynnema mirum DSM 43827 8329701 YP_003103160.1 CDS Amir_5496 NC_013093.1 6527847 6528404 D PFAM: protein of unknown function DUF309; KEGG: dvm:DvMF_2231 protein of unknown function DUF309; hypothetical protein 6527847..6528404 Actinosynnema mirum DSM 43827 8329702 YP_003103161.1 CDS Amir_5497 NC_013093.1 6528401 6529045 D PFAM: GCN5-related N-acetyltransferase; KEGG: pla:Plav_0958 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 6528401..6529045 Actinosynnema mirum DSM 43827 8329703 YP_003103162.1 CDS Amir_5498 NC_013093.1 6529077 6529259 D hypothetical protein 6529077..6529259 Actinosynnema mirum DSM 43827 8329704 YP_003103163.1 CDS Amir_5499 NC_013093.1 6529973 6530125 R hypothetical protein complement(6529973..6530125) Actinosynnema mirum DSM 43827 8329705 YP_003103164.1 CDS Amir_5500 NC_013093.1 6530198 6531400 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: acp:A2cp1_3940 hypothetical protein; helix-turn-helix domain-containing protein complement(6530198..6531400) Actinosynnema mirum DSM 43827 8329706 YP_003103165.1 CDS Amir_5501 NC_013093.1 6532862 6533632 D PFAM: protein of unknown function DUF540; KEGG: maq:Maqu_3616 hypothetical protein; hypothetical protein 6532862..6533632 Actinosynnema mirum DSM 43827 8329707 YP_003103166.1 CDS Amir_5502 NC_013093.1 6533778 6534605 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: AGAP008296-PA; peptidase S1 and S6 chymotrypsin/Hap complement(6533778..6534605) Actinosynnema mirum DSM 43827 8329708 YP_003103167.1 CDS Amir_5503 NC_013093.1 6534783 6535157 D PFAM: peptidylprolyl isomerase FKBP-type; KEGG: tbd:Tbd_2152 peptidyl-prolyl cis-trans isomerase; FKBP-type peptidylprolyl isomerase 6534783..6535157 Actinosynnema mirum DSM 43827 8329709 YP_003103168.1 CDS Amir_5504 NC_013093.1 6535463 6536029 D KEGG: hypothetical protein; hypothetical protein 6535463..6536029 Actinosynnema mirum DSM 43827 8329710 YP_003103169.1 CDS Amir_5505 NC_013093.1 6536137 6537210 D KEGG: predicted gene, EG114600; hypothetical protein 6536137..6537210 Actinosynnema mirum DSM 43827 8329711 YP_003103170.1 CDS Amir_5506 NC_013093.1 6537318 6538505 R KEGG: hne:HNE_2077 hypothetical protein; hypothetical protein complement(6537318..6538505) Actinosynnema mirum DSM 43827 8329712 YP_003103171.1 CDS Amir_5507 NC_013093.1 6538702 6539286 D KEGG: pla:Plav_3469 hypothetical protein; hypothetical protein 6538702..6539286 Actinosynnema mirum DSM 43827 8329713 YP_003103172.1 CDS Amir_5508 NC_013093.1 6540197 6540853 D PFAM: hypothetical protein; KEGG: rsh:Rsph17029_3025 hypothetical protein; hypothetical protein 6540197..6540853 Actinosynnema mirum DSM 43827 8329714 YP_003103173.1 CDS Amir_5509 NC_013093.1 6541042 6541629 R PFAM: GCN5-related N-acetyltransferase; KEGG: scl:sce8211 adenylattransferase; GCN5-like N-acetyltransferase complement(6541042..6541629) Actinosynnema mirum DSM 43827 8329715 YP_003103174.1 CDS Amir_5510 NC_013093.1 6541663 6542280 R hypothetical protein complement(6541663..6542280) Actinosynnema mirum DSM 43827 8329716 YP_003103175.1 CDS Amir_5511 NC_013093.1 6542277 6542960 R PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: dal:Dalk_5197 transcriptional regulator, Crp/Fnr family; Crp/Fnr family transcriptional regulator complement(6542277..6542960) Actinosynnema mirum DSM 43827 8329717 YP_003103176.1 CDS Amir_5512 NC_013093.1 6543220 6545124 R PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; dienelactone hydrolase; hypothetical protein; acetyl xylan esterase; KEGG: bsu:BSU32230 hypothetical protein; peptidase S9 prolyl oligopeptidase active site domain-containing protein complement(6543220..6545124) Actinosynnema mirum DSM 43827 8329718 YP_003103177.1 CDS Amir_5513 NC_013093.1 6545189 6546181 R PFAM: integral membrane protein TerC; KEGG: csa:Csal_1104 integral membrane protein TerC; integral membrane protein TerC complement(6545189..6546181) Actinosynnema mirum DSM 43827 8329719 YP_003103178.1 CDS Amir_5514 NC_013093.1 6546560 6549466 D PFAM: ABC transporter; peptidase S15; alpha/beta hydrolase fold; SMART: ATPase AAA; KEGG: bcz:BCZK3372 bacitracin ABC transporter, ATP- binding protein; ABC transporter 6546560..6549466 Actinosynnema mirum DSM 43827 8329720 YP_003103179.1 CDS Amir_5515 NC_013093.1 6549463 6550446 D KEGG: rso:RSp1372 NosY transmembrane protein; hypothetical protein 6549463..6550446 Actinosynnema mirum DSM 43827 8329721 YP_003103180.1 CDS Amir_5516 NC_013093.1 6550512 6552683 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(6550512..6552683) Actinosynnema mirum DSM 43827 8329722 YP_003103181.1 CDS Amir_5517 NC_013093.1 6552768 6554081 R KEGG: hypothetical protein; hypothetical protein complement(6552768..6554081) Actinosynnema mirum DSM 43827 8329723 YP_003103182.1 CDS Amir_5518 NC_013093.1 6554188 6554733 D hypothetical protein 6554188..6554733 Actinosynnema mirum DSM 43827 8329724 YP_003103183.1 CDS Amir_5519 NC_013093.1 6554881 6555402 D hypothetical protein 6554881..6555402 Actinosynnema mirum DSM 43827 8329725 YP_003103184.1 CDS coaE NC_013093.1 6555372 6556556 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain; dephospho-CoA kinase/protein folding accessory domain-containing protein complement(6555372..6556556) Actinosynnema mirum DSM 43827 8329726 YP_003103185.1 CDS Amir_5521 NC_013093.1 6556597 6557217 R hypothetical protein complement(6556597..6557217) Actinosynnema mirum DSM 43827 8329727 YP_003103186.1 CDS rpsA NC_013093.1 6557513 6559000 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(6557513..6559000) Actinosynnema mirum DSM 43827 8329728 YP_003103187.1 CDS Amir_5523 NC_013093.1 6559192 6560022 D PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: ank:AnaeK_1219 methyltransferase type 11; type 11 methyltransferase 6559192..6560022 Actinosynnema mirum DSM 43827 8329729 YP_003103188.1 CDS Amir_5524 NC_013093.1 6560033 6560959 D PFAM: GCN5-related N-acetyltransferase; KEGG: sil:SPO0965 acetyltransferase; GCN5-like N-acetyltransferase 6560033..6560959 Actinosynnema mirum DSM 43827 8329730 YP_003103189.1 CDS Amir_5525 NC_013093.1 6561709 6562344 D KEGG: hypothetical protein; hypothetical protein 6561709..6562344 Actinosynnema mirum DSM 43827 8329731 YP_003103190.1 CDS Amir_5526 NC_013093.1 6562341 6564236 D TIGRFAM: YhgE/Pip C-terminal domain protein; YhgE/Pip N-terminal domain protein; PFAM: ABC transporter; KEGG: bce:BC5221 phage infection protein; YhgE/Pip C-terminal domain-containing protein 6562341..6564236 Actinosynnema mirum DSM 43827 8329732 YP_003103191.1 CDS Amir_5527 NC_013093.1 6564233 6564844 D PFAM: regulatory protein TetR; KEGG: scl:sce9124 TetR family transcriptional regulator; TetR family transcriptional regulator 6564233..6564844 Actinosynnema mirum DSM 43827 8329733 YP_003103192.1 CDS Amir_5528 NC_013093.1 6564890 6565510 R KEGG: bcz:BCZK1848 short chain dehydrogenase; hypothetical protein complement(6564890..6565510) Actinosynnema mirum DSM 43827 8329734 YP_003103193.1 CDS Amir_5529 NC_013093.1 6565585 6566193 R KEGG: cvi:CV_0278 hypothetical protein; hypothetical protein complement(6565585..6566193) Actinosynnema mirum DSM 43827 8329735 YP_003103194.1 CDS Amir_5530 NC_013093.1 6566485 6567720 R PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: NAD binding Rossmann fold oxidoreductase; K00540; oxidoreductase domain-containing protein complement(6566485..6567720) Actinosynnema mirum DSM 43827 8329736 YP_003103195.1 CDS Amir_5531 NC_013093.1 6567754 6567945 R KEGG: bur:Bcep18194_B0875 hypothetical protein; hypothetical protein complement(6567754..6567945) Actinosynnema mirum DSM 43827 8329737 YP_003103196.1 CDS Amir_5532 NC_013093.1 6568951 6571617 R KEGG: afw:Anae109_2455 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; 3'-5' exonuclease; Helix-hairpin-helix domain protein class 2; DNA polymerase I complement(6568951..6571617) Actinosynnema mirum DSM 43827 8329738 YP_003103197.1 CDS Amir_5533 NC_013093.1 6571672 6572082 D PFAM: thioesterase superfamily protein; KEGG: eum:ECUMN_0691 esterase; thioesterase superfamily protein 6571672..6572082 Actinosynnema mirum DSM 43827 8329739 YP_003103198.1 CDS Amir_5534 NC_013093.1 6572087 6572605 D KEGG: bcr:BCAH187_A1173 hypothetical protein; hypothetical protein 6572087..6572605 Actinosynnema mirum DSM 43827 8329740 YP_003103199.1 CDS Amir_5535 NC_013093.1 6572684 6573388 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: gbm:Gbem_1946 ABC transporter protein; ABC transporter complement(6572684..6573388) Actinosynnema mirum DSM 43827 8329741 YP_003103200.1 CDS Amir_5536 NC_013093.1 6573378 6574154 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bmj:BMULJ_02460 branched-chain amino acid transport system ATP-binding protein; ABC transporter complement(6573378..6574154) Actinosynnema mirum DSM 43827 8329742 YP_003103201.1 CDS Amir_5537 NC_013093.1 6574151 6575308 R PFAM: inner-membrane translocator; KEGG: bbr:BB2027 ABC transport protein, ATP-binding component; inner-membrane translocator complement(6574151..6575308) Actinosynnema mirum DSM 43827 8329743 YP_003103202.1 CDS Amir_5538 NC_013093.1 6575305 6576267 R PFAM: inner-membrane translocator; KEGG: cvi:CV_1503 leucine/isoleucine/valine transport system permease protein; inner-membrane translocator complement(6575305..6576267) Actinosynnema mirum DSM 43827 8329744 YP_003103203.1 CDS Amir_5539 NC_013093.1 6576393 6577571 R PFAM: Extracellular ligand-binding receptor; KEGG: azo:azo3730 leucine-specific binding protein; Extracellular ligand-binding receptor complement(6576393..6577571) Actinosynnema mirum DSM 43827 8329745 YP_003103204.1 CDS Amir_5540 NC_013093.1 6577885 6578487 R PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; KEGG: gme:Gmet_0660 response regulator receiver/ANTAR domain-containing protein; response regulator receiver and ANTAR domain-containing protein complement(6577885..6578487) Actinosynnema mirum DSM 43827 8329746 YP_003103205.1 CDS Amir_5541 NC_013093.1 6579184 6580137 R hypothetical protein complement(6579184..6580137) Actinosynnema mirum DSM 43827 8329747 YP_003103206.1 CDS Amir_5542 NC_013093.1 6580562 6581077 D PFAM: protein of unknown function DUF664; hypothetical protein 6580562..6581077 Actinosynnema mirum DSM 43827 8329748 YP_003103207.1 CDS Amir_5543 NC_013093.1 6581555 6582871 R KEGG: hypothetical protein; hypothetical protein complement(6581555..6582871) Actinosynnema mirum DSM 43827 8329749 YP_003103208.1 CDS Amir_5544 NC_013093.1 6582967 6583431 D PFAM: CoA-binding domain protein; KEGG: mag:amb2851 hypothetical protein; CoA-binding domain-containing protein 6582967..6583431 Actinosynnema mirum DSM 43827 8329750 YP_003103209.1 CDS Amir_5545 NC_013093.1 6583409 6583789 R PFAM: endoribonuclease L-PSP; KEGG: nmu:Nmul_A2263 endoribonuclease L-PSP; endoribonuclease L-PSP complement(6583409..6583789) Actinosynnema mirum DSM 43827 8329751 YP_003103210.1 CDS Amir_5546 NC_013093.1 6583847 6584641 D PFAM: alpha/beta hydrolase fold; KEGG: xau:Xaut_2294 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 6583847..6584641 Actinosynnema mirum DSM 43827 8329752 YP_003103211.1 CDS Amir_5547 NC_013093.1 6585183 6587426 D KEGG: disease resistance-responsive family protein / fibroin-related; signal transduction protein with Nacht domain 6585183..6587426 Actinosynnema mirum DSM 43827 8329753 YP_003103212.1 CDS Amir_5548 NC_013093.1 6587522 6588352 R PFAM: pentapeptide repeat protein; KEGG: bat:BAS3175 pentapeptide repeat-containing protein; pentapeptide repeat-containing protein complement(6587522..6588352) Actinosynnema mirum DSM 43827 8329754 YP_003103213.1 CDS Amir_5549 NC_013093.1 6588700 6590520 R KEGG: bpt:Bpet0900 DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; HRDC domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein; ATP-dependent DNA helicase RecQ complement(6588700..6590520) Actinosynnema mirum DSM 43827 8329755 YP_003103214.1 CDS Amir_5550 NC_013093.1 6590530 6591894 R KEGG: bat:BAS3517 hypothetical protein; hypothetical protein complement(6590530..6591894) Actinosynnema mirum DSM 43827 8329756 YP_003103215.1 CDS Amir_5551 NC_013093.1 6591979 6592734 D KEGG: hypothetical protein; restriction endonuclease-like protein 6591979..6592734 Actinosynnema mirum DSM 43827 8329757 YP_003103216.1 CDS Amir_5552 NC_013093.1 6592742 6593104 R hypothetical protein complement(6592742..6593104) Actinosynnema mirum DSM 43827 8329758 YP_003103217.1 CDS Amir_5553 NC_013093.1 6593140 6594543 D KEGG: ade:Adeh_0244 LigA; hypothetical protein 6593140..6594543 Actinosynnema mirum DSM 43827 8329759 YP_003103218.1 CDS Amir_5554 NC_013093.1 6594572 6594829 D hypothetical protein 6594572..6594829 Actinosynnema mirum DSM 43827 8329760 YP_003103219.1 CDS Amir_5555 NC_013093.1 6594888 6595355 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator complement(6594888..6595355) Actinosynnema mirum DSM 43827 8329761 YP_003103220.1 CDS Amir_5556 NC_013093.1 6595479 6595742 D KEGG: cja:CJA_3805 helix-turn-helix domain protein; XRE family transcriptional regulator 6595479..6595742 Actinosynnema mirum DSM 43827 8329762 YP_003103221.1 CDS Amir_5557 NC_013093.1 6595742 6596194 D hypothetical protein 6595742..6596194 Actinosynnema mirum DSM 43827 8329763 YP_003103222.1 CDS Amir_5558 NC_013093.1 6596267 6597244 D hypothetical protein 6596267..6597244 Actinosynnema mirum DSM 43827 8329764 YP_003103223.1 CDS Amir_5559 NC_013093.1 6597241 6598422 D hypothetical protein 6597241..6598422 Actinosynnema mirum DSM 43827 8329765 YP_003103224.1 CDS Amir_5560 NC_013093.1 6598616 6599356 D hypothetical protein 6598616..6599356 Actinosynnema mirum DSM 43827 8329766 YP_003103225.1 CDS Amir_5561 NC_013093.1 6599353 6599703 D hypothetical protein 6599353..6599703 Actinosynnema mirum DSM 43827 8329767 YP_003103226.1 CDS Amir_5562 NC_013093.1 6599775 6600209 D PFAM: HNH endonuclease; KEGG: sus:Acid_3418 HNH endonuclease; HNH endonuclease 6599775..6600209 Actinosynnema mirum DSM 43827 8329768 YP_003103227.1 CDS Amir_5563 NC_013093.1 6600206 6600715 D hypothetical protein 6600206..6600715 Actinosynnema mirum DSM 43827 8329769 YP_003103228.1 CDS Amir_5564 NC_013093.1 6600746 6601606 D KEGG: similar to homologue to Drosophila photoreceptor protein calphotin; hypothetical protein 6600746..6601606 Actinosynnema mirum DSM 43827 8329770 YP_003103229.1 CDS Amir_5565 NC_013093.1 6601603 6601881 D hypothetical protein 6601603..6601881 Actinosynnema mirum DSM 43827 8329771 YP_003103230.1 CDS Amir_5566 NC_013093.1 6602048 6602350 D hypothetical protein 6602048..6602350 Actinosynnema mirum DSM 43827 8329772 YP_003103231.1 CDS Amir_5567 NC_013093.1 6602468 6602929 D hypothetical protein 6602468..6602929 Actinosynnema mirum DSM 43827 8329773 YP_003103232.1 CDS Amir_5568 NC_013093.1 6603093 6603497 D hypothetical protein 6603093..6603497 Actinosynnema mirum DSM 43827 8329774 YP_003103233.1 CDS Amir_5569 NC_013093.1 6603494 6604198 D hypothetical protein 6603494..6604198 Actinosynnema mirum DSM 43827 8329775 YP_003103234.1 CDS Amir_5570 NC_013093.1 6604654 6604848 D hypothetical protein 6604654..6604848 Actinosynnema mirum DSM 43827 8329776 YP_003103235.1 CDS Amir_5571 NC_013093.1 6604845 6605237 D hypothetical protein 6604845..6605237 Actinosynnema mirum DSM 43827 8329777 YP_003103236.1 CDS Amir_5572 NC_013093.1 6605247 6606314 D KEGG: ppg:PputGB1_3430 hypothetical protein; hypothetical protein 6605247..6606314 Actinosynnema mirum DSM 43827 8329778 YP_003103237.1 CDS Amir_5573 NC_013093.1 6606318 6606803 D KEGG: aba:Acid345_1977 metallophosphoesterase; metallophosphoesterase 6606318..6606803 Actinosynnema mirum DSM 43827 8329779 YP_003103238.1 CDS Amir_5574 NC_013093.1 6606806 6608296 D PFAM: C-5 cytosine-specific DNA methylase; KEGG: vei:Veis_3654 C-5 cytosine-specific DNA methylase; C-5 cytosine-specific DNA methylase 6606806..6608296 Actinosynnema mirum DSM 43827 8329780 YP_003103239.1 CDS Amir_5575 NC_013093.1 6608323 6609000 D KEGG: mxa:MXAN_2991 adventurous gliding motility protein AglZ; hypothetical protein 6608323..6609000 Actinosynnema mirum DSM 43827 8329781 YP_003103240.1 CDS Amir_5576 NC_013093.1 6609004 6609198 D hypothetical protein 6609004..6609198 Actinosynnema mirum DSM 43827 8329782 YP_003103241.1 CDS Amir_5577 NC_013093.1 6609275 6609589 D PFAM: transcription factor WhiB; transcription factor WhiB 6609275..6609589 Actinosynnema mirum DSM 43827 8329783 YP_003103242.1 CDS Amir_5578 NC_013093.1 6609589 6610083 D KEGG: hypothetical protein; hypothetical protein 6609589..6610083 Actinosynnema mirum DSM 43827 8329784 YP_003103243.1 CDS Amir_5579 NC_013093.1 6610080 6610670 D hypothetical protein 6610080..6610670 Actinosynnema mirum DSM 43827 8329785 YP_003103244.1 CDS Amir_5580 NC_013093.1 6610667 6610762 D hypothetical protein 6610667..6610762 Actinosynnema mirum DSM 43827 8329786 YP_003103245.1 CDS Amir_5581 NC_013093.1 6610772 6610969 D hypothetical protein 6610772..6610969 Actinosynnema mirum DSM 43827 8329787 YP_003103246.1 CDS Amir_5582 NC_013093.1 6611025 6611285 D hypothetical protein 6611025..6611285 Actinosynnema mirum DSM 43827 8329788 YP_003103247.1 CDS Amir_5583 NC_013093.1 6611322 6612224 D KEGG: pzu:PHZ_c2649 5-methyltetrahydrofolate-- homocysteine methyltransferase; hypothetical protein 6611322..6612224 Actinosynnema mirum DSM 43827 8329789 YP_003103248.1 CDS Amir_5584 NC_013093.1 6612239 6612607 D hypothetical protein 6612239..6612607 Actinosynnema mirum DSM 43827 8329790 YP_003103249.1 CDS Amir_5585 NC_013093.1 6612878 6613822 D PFAM: hypothetical protein; KEGG: gme:Gmet_0890 smf protein; hypothetical protein 6612878..6613822 Actinosynnema mirum DSM 43827 8329791 YP_003103250.1 CDS Amir_5586 NC_013093.1 6613839 6614582 D KEGG: dol:Dole_1907 phosphoribosyltransferase; phosphoribosyltransferase 6613839..6614582 Actinosynnema mirum DSM 43827 8329792 YP_003103251.1 CDS Amir_5587 NC_013093.1 6614684 6614878 R hypothetical protein complement(6614684..6614878) Actinosynnema mirum DSM 43827 8329793 YP_003103252.1 CDS Amir_5588 NC_013093.1 6614878 6615633 R KEGG: GK12364 gene product from transcript GK12364- RA; hypothetical protein complement(6614878..6615633) Actinosynnema mirum DSM 43827 8329794 YP_003103253.1 CDS Amir_5589 NC_013093.1 6615739 6615951 R hypothetical protein complement(6615739..6615951) Actinosynnema mirum DSM 43827 8329795 YP_003103254.1 CDS Amir_5590 NC_013093.1 6615997 6616725 R PFAM: membrane-bound metal-dependent hydrolase; KEGG: gbe:GbCGDNIH1_1245 predicted membrane-bound metal-dependent hydrolase; membrane-bound metal-dependent hydrolase complement(6615997..6616725) Actinosynnema mirum DSM 43827 8329796 YP_003103255.1 CDS Amir_5591 NC_013093.1 6616857 6617591 R KEGG: fibrocystin-L-like protein; hypothetical protein complement(6616857..6617591) Actinosynnema mirum DSM 43827 8329797 YP_003103256.1 CDS Amir_5592 NC_013093.1 6617855 6620113 R KEGG: ade:Adeh_4037 MaoC-like dehydratase; hypothetical protein complement(6617855..6620113) Actinosynnema mirum DSM 43827 8329798 YP_003103257.1 CDS Amir_5593 NC_013093.1 6620176 6621246 R KEGG: PF6; flagellar central pair-associated protein; hypothetical protein complement(6620176..6621246) Actinosynnema mirum DSM 43827 8329799 YP_003103258.1 CDS Amir_5594 NC_013093.1 6621246 6621689 R hypothetical protein complement(6621246..6621689) Actinosynnema mirum DSM 43827 8329800 YP_003103259.1 CDS Amir_5595 NC_013093.1 6621701 6623071 R KEGG: pin:Ping_0445 colicin uptake-like protein; hypothetical protein complement(6621701..6623071) Actinosynnema mirum DSM 43827 8329801 YP_003103260.1 CDS Amir_5596 NC_013093.1 6623132 6623800 R hypothetical protein complement(6623132..6623800) Actinosynnema mirum DSM 43827 8329802 YP_003103261.1 CDS Amir_5597 NC_013093.1 6623869 6624387 R KEGG: scl:sce8592 hypothetical protein; hypothetical protein complement(6623869..6624387) Actinosynnema mirum DSM 43827 8329803 YP_003103262.1 CDS Amir_5598 NC_013093.1 6624384 6624881 R PFAM: NUDIX hydrolase; KEGG: scl:sce2352 hypothetical protein; NUDIX hydrolase complement(6624384..6624881) Actinosynnema mirum DSM 43827 8329804 YP_003103263.1 CDS Amir_5599 NC_013093.1 6624973 6625239 R hypothetical protein complement(6624973..6625239) Actinosynnema mirum DSM 43827 8329805 YP_003103264.1 CDS Amir_5602 NC_013093.1 6625791 6626732 R hypothetical protein complement(6625791..6626732) Actinosynnema mirum DSM 43827 8329808 YP_003103265.1 CDS Amir_5603 NC_013093.1 6626809 6626967 R hypothetical protein complement(6626809..6626967) Actinosynnema mirum DSM 43827 8329809 YP_003103266.1 CDS Amir_5604 NC_013093.1 6627012 6627218 R hypothetical protein complement(6627012..6627218) Actinosynnema mirum DSM 43827 8329810 YP_003103267.1 CDS Amir_5605 NC_013093.1 6627335 6628135 D PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sil:SPO0467 GntR family transcriptional regulator; GntR family transcriptional regulator 6627335..6628135 Actinosynnema mirum DSM 43827 8329811 YP_003103268.1 CDS Amir_5606 NC_013093.1 6628276 6628458 D hypothetical protein 6628276..6628458 Actinosynnema mirum DSM 43827 8329812 YP_003103269.1 CDS Amir_5607 NC_013093.1 6628549 6629106 D hypothetical protein 6628549..6629106 Actinosynnema mirum DSM 43827 8329813 YP_003103270.1 CDS Amir_5608 NC_013093.1 6629103 6629558 D hypothetical protein 6629103..6629558 Actinosynnema mirum DSM 43827 8329814 YP_003103271.1 CDS Amir_5609 NC_013093.1 6629882 6630007 D hypothetical protein 6629882..6630007 Actinosynnema mirum DSM 43827 8329815 YP_003103272.1 CDS Amir_5610 NC_013093.1 6630039 6630329 D hypothetical protein 6630039..6630329 Actinosynnema mirum DSM 43827 8329816 YP_003103273.1 CDS Amir_5611 NC_013093.1 6630791 6632560 D PFAM: lipolytic protein G-D-S-L family; KEGG: met:M446_3487 triple helix repeat-containing COllagen; G-D-S-L family lipolytic protein 6630791..6632560 Actinosynnema mirum DSM 43827 8329817 YP_003103274.1 CDS Amir_5612 NC_013093.1 6632577 6632963 D KEGG: bav:BAV1457 phage protein; phage protein 6632577..6632963 Actinosynnema mirum DSM 43827 8329818 YP_003103275.1 CDS Amir_5613 NC_013093.1 6632974 6633249 D hypothetical protein 6632974..6633249 Actinosynnema mirum DSM 43827 8329819 YP_003103276.1 CDS Amir_5614 NC_013093.1 6633246 6633665 D hypothetical protein 6633246..6633665 Actinosynnema mirum DSM 43827 8329820 YP_003103277.1 CDS Amir_5615 NC_013093.1 6633662 6634258 D KEGG: nwi:Nwi_1556 hypothetical protein; hypothetical protein 6633662..6634258 Actinosynnema mirum DSM 43827 8329821 YP_003103278.1 CDS Amir_5616 NC_013093.1 6634262 6634528 D hypothetical protein 6634262..6634528 Actinosynnema mirum DSM 43827 8329822 YP_003103279.1 CDS Amir_5617 NC_013093.1 6634515 6634727 D hypothetical protein 6634515..6634727 Actinosynnema mirum DSM 43827 8329823 YP_003103280.1 CDS Amir_5618 NC_013093.1 6634986 6635186 D hypothetical protein 6634986..6635186 Actinosynnema mirum DSM 43827 8329824 YP_003103281.1 CDS Amir_5619 NC_013093.1 6635186 6635635 D hypothetical protein 6635186..6635635 Actinosynnema mirum DSM 43827 8329825 YP_003103282.1 CDS Amir_5620 NC_013093.1 6635632 6637245 D PFAM: terminase; KEGG: acp:A2cp1_1302 terminase; terminase 6635632..6637245 Actinosynnema mirum DSM 43827 8329826 YP_003103283.1 CDS Amir_5621 NC_013093.1 6637256 6638680 D PFAM: protein of unknown function DUF1483; hypothetical protein 6637256..6638680 Actinosynnema mirum DSM 43827 8329827 YP_003103284.1 CDS Amir_5622 NC_013093.1 6638677 6639720 D hypothetical protein 6638677..6639720 Actinosynnema mirum DSM 43827 8329828 YP_003103285.1 CDS Amir_5623 NC_013093.1 6639767 6640432 D KEGG: dal:Dalk_5199 hypothetical protein; hypothetical protein 6639767..6640432 Actinosynnema mirum DSM 43827 8329829 YP_003103286.1 CDS Amir_5624 NC_013093.1 6640429 6640620 D hypothetical protein 6640429..6640620 Actinosynnema mirum DSM 43827 8329830 YP_003103287.1 CDS Amir_5625 NC_013093.1 6640620 6641975 D KEGG: acr:Acry_2510 hypothetical protein; hypothetical protein 6640620..6641975 Actinosynnema mirum DSM 43827 8329831 YP_003103288.1 CDS Amir_5626 NC_013093.1 6641975 6642439 D KEGG: bpa:BPP1618 autotransporter; hypothetical protein 6641975..6642439 Actinosynnema mirum DSM 43827 8329832 YP_003103289.1 CDS Amir_5627 NC_013093.1 6642450 6643067 D hypothetical protein 6642450..6643067 Actinosynnema mirum DSM 43827 8329833 YP_003103290.1 CDS Amir_5628 NC_013093.1 6643199 6643567 D hypothetical protein 6643199..6643567 Actinosynnema mirum DSM 43827 8329834 YP_003103291.1 CDS Amir_5629 NC_013093.1 6643577 6643900 D hypothetical protein 6643577..6643900 Actinosynnema mirum DSM 43827 8329835 YP_003103292.1 CDS Amir_5630 NC_013093.1 6643903 6644205 D hypothetical protein 6643903..6644205 Actinosynnema mirum DSM 43827 8329836 YP_003103293.1 CDS Amir_5631 NC_013093.1 6644215 6644649 D hypothetical protein 6644215..6644649 Actinosynnema mirum DSM 43827 8329837 YP_003103294.1 CDS Amir_5632 NC_013093.1 6644788 6645339 D hypothetical protein 6644788..6645339 Actinosynnema mirum DSM 43827 8329838 YP_003103295.1 CDS Amir_5633 NC_013093.1 6645354 6645725 D hypothetical protein 6645354..6645725 Actinosynnema mirum DSM 43827 8329839 YP_003103296.1 CDS Amir_5634 NC_013093.1 6645812 6646225 D hypothetical protein 6645812..6646225 Actinosynnema mirum DSM 43827 8329840 YP_003103297.1 CDS Amir_5635 NC_013093.1 6646242 6650357 D TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: mgm:Mmc1_2034 phage tail tape measure protein, TP901 family; phage tail tape measure protein, TP901 family 6646242..6650357 Actinosynnema mirum DSM 43827 8329841 YP_003103298.1 CDS Amir_5636 NC_013093.1 6650368 6651813 D KEGG: similar to endo-1,4-beta-glucanase; hypothetical protein 6650368..6651813 Actinosynnema mirum DSM 43827 8329842 YP_003103299.1 CDS Amir_5637 NC_013093.1 6651863 6652993 D KEGG: mag:amb1782 PRY3 protein; hypothetical protein 6651863..6652993 Actinosynnema mirum DSM 43827 8329843 YP_003103300.1 CDS Amir_5638 NC_013093.1 6652990 6654129 D hypothetical protein 6652990..6654129 Actinosynnema mirum DSM 43827 8329844 YP_003103301.1 CDS Amir_5639 NC_013093.1 6654129 6654839 D hypothetical protein 6654129..6654839 Actinosynnema mirum DSM 43827 8329845 YP_003103302.1 CDS Amir_5640 NC_013093.1 6654840 6655265 R KEGG: hypothetical protein; hypothetical protein complement(6654840..6655265) Actinosynnema mirum DSM 43827 8329846 YP_003103303.1 CDS Amir_5641 NC_013093.1 6655352 6655609 D hypothetical protein 6655352..6655609 Actinosynnema mirum DSM 43827 8329847 YP_003103304.1 CDS Amir_5642 NC_013093.1 6655606 6655986 D hypothetical protein 6655606..6655986 Actinosynnema mirum DSM 43827 8329848 YP_003103305.1 CDS Amir_5643 NC_013093.1 6655983 6656990 D PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; KEGG: sil:SPO3258 glycosy hydrolase family protein; glycoside hydrolase family protein 6655983..6656990 Actinosynnema mirum DSM 43827 8329849 YP_003103306.1 CDS Amir_5644 NC_013093.1 6656987 6658045 D hypothetical protein 6656987..6658045 Actinosynnema mirum DSM 43827 8329850 YP_003103307.1 CDS Amir_5646 NC_013093.1 6658454 6658687 D KEGG: psb:Psyr_2800 hypothetical protein; hypothetical protein 6658454..6658687 Actinosynnema mirum DSM 43827 8329852 YP_003103308.1 CDS Amir_5647 NC_013093.1 6658747 6659979 R PFAM: integrase family protein; KEGG: bce:BC1272 DNA integration/recombination/invertion protein; integrase family protein complement(6658747..6659979) Actinosynnema mirum DSM 43827 8329853 YP_003103309.1 CDS Amir_5648 NC_013093.1 6660208 6660489 R PFAM: protein of unknown function DUF156; KEGG: acp:A2cp1_3648 protein of unknown function DUF156; hypothetical protein complement(6660208..6660489) Actinosynnema mirum DSM 43827 8329855 YP_003103310.1 CDS Amir_5649 NC_013093.1 6660753 6661094 D hypothetical protein 6660753..6661094 Actinosynnema mirum DSM 43827 8329856 YP_003103311.1 CDS Amir_5650 NC_013093.1 6661156 6663174 R TIGRFAM: para-aminobenzoate synthase, subunit I; glutamine amidotransferase of anthranilate synthase; PFAM: Chorismate binding-like; glutamine amidotransferase class-I; Anthranilate synthase component I domain protein; KEGG: rpd:RPD_2897 para-aminobenzoate synthase, component I; para-aminobenzoate synthase, subunit I complement(6661156..6663174) Actinosynnema mirum DSM 43827 8329857 YP_003103312.1 CDS Amir_5651 NC_013093.1 6663234 6663959 R hypothetical protein complement(6663234..6663959) Actinosynnema mirum DSM 43827 8329858 YP_003103313.1 CDS Amir_5652 NC_013093.1 6663953 6664453 R TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: pca:Pcar_3124 RNA polymerase, sigma-E factor; ECF subfamily RNA polymerase sigma-24 subunit complement(6663953..6664453) Actinosynnema mirum DSM 43827 8329859 YP_003103314.1 CDS Amir_5653 NC_013093.1 6664572 6665831 D PFAM: metallophosphoesterase; KEGG: scl:sce7577 integral membrane protein; metallophosphoesterase 6664572..6665831 Actinosynnema mirum DSM 43827 8329860 YP_003103315.1 CDS Amir_5654 NC_013093.1 6665882 6667075 D PFAM: Orn/DAP/Arg decarboxylase 2; alanine racemase domain protein; KEGG: mag:amb1388 diaminopimelate decarboxylase; Orn/DAP/Arg decarboxylase 2 6665882..6667075 Actinosynnema mirum DSM 43827 8329861 YP_003103316.1 CDS Amir_5655 NC_013093.1 6667146 6667559 D TIGRFAM: S-adenosylmethionine decarboxylase proenzyme; PFAM: S-adenosylmethionine decarboxylase related; KEGG: bcr:BCAH187_A5378 adenosylmethionine decarboxylase 2; S-adenosylmethionine decarboxylase proenzyme 6667146..6667559 Actinosynnema mirum DSM 43827 8329862 YP_003103317.1 CDS Amir_5656 NC_013093.1 6667556 6668401 D PFAM: spermine synthase; KEGG: jan:Jann_0855 spermidine synthase; spermine synthase 6667556..6668401 Actinosynnema mirum DSM 43827 8329863 YP_003103318.1 CDS Amir_5657 NC_013093.1 6668504 6670585 R PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: afw:Anae109_2431 peptidase S9B dipeptidylpeptidase IV subunit; peptidase S9 prolyl oligopeptidase active site domain-containing protein complement(6668504..6670585) Actinosynnema mirum DSM 43827 8329864 YP_003103319.1 CDS Amir_5658 NC_013093.1 6670710 6671315 R PFAM: nitroreductase; KEGG: lch:Lcho_1290 nitroreductase; hypothetical protein complement(6670710..6671315) Actinosynnema mirum DSM 43827 8329865 YP_003103320.1 CDS Amir_5659 NC_013093.1 6671480 6672745 R PFAM: glycine hydroxymethyltransferase; aminotransferase class I and II; aromatic amino acid beta- eliminating lyase/threonine aldolase; KEGG: rce:RC1_1342 serine hydroxymethyltransferase; glycine hydroxymethyltransferase complement(6671480..6672745) Actinosynnema mirum DSM 43827 8329866 YP_003103321.1 CDS gcvT NC_013093.1 6672763 6673860 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(6672763..6673860) Actinosynnema mirum DSM 43827 8329867 YP_003103322.1 CDS Amir_5661 NC_013093.1 6674048 6674350 R KEGG: bba:Bd3290 hypothetical protein; hypothetical protein complement(6674048..6674350) Actinosynnema mirum DSM 43827 8329868 YP_003103323.1 CDS Amir_5662 NC_013093.1 6674374 6674844 R glucitol operon activator-like protein complement(6674374..6674844) Actinosynnema mirum DSM 43827 8329869 YP_003103324.1 CDS Amir_5663 NC_013093.1 6675471 6675962 R hypothetical protein complement(6675471..6675962) Actinosynnema mirum DSM 43827 8329870 YP_003103325.1 CDS Amir_5664 NC_013093.1 6676142 6676288 R hypothetical protein complement(6676142..6676288) Actinosynnema mirum DSM 43827 8329871 YP_003103326.1 CDS Amir_5665 NC_013093.1 6677645 6678766 R PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rfr:Rfer_0993 L-carnitine dehydratase/bile acid-inducible protein F; L-carnitine dehydratase/bile acid-inducible protein F complement(6677645..6678766) Actinosynnema mirum DSM 43827 8329872 YP_003103327.1 CDS Amir_5666 NC_013093.1 6678766 6679911 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: rce:RC1_0378 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein complement(6678766..6679911) Actinosynnema mirum DSM 43827 8329873 YP_003103328.1 CDS Amir_5667 NC_013093.1 6679981 6680553 D PFAM: GCN5-related N-acetyltransferase; KEGG: swp:swp_4165 GCN5-like N-acetyltransferase; GCN5-like N-acetyltransferase 6679981..6680553 Actinosynnema mirum DSM 43827 8329874 YP_003103329.1 CDS Amir_5668 NC_013093.1 6680614 6681816 D TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: pag:PLES_35931 acyl-CoA thiolase; acetyl-CoA acetyltransferase 6680614..6681816 Actinosynnema mirum DSM 43827 8329875 YP_003103330.1 CDS Amir_5669 NC_013093.1 6681818 6683872 D PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: pmy:Pmen_2590 short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase 6681818..6683872 Actinosynnema mirum DSM 43827 8329876 YP_003103331.1 CDS Amir_5670 NC_013093.1 6683863 6684870 R PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pmy:Pmen_2972 AraC family transcriptional regulator; AraC family transcriptional regulator complement(6683863..6684870) Actinosynnema mirum DSM 43827 8329877 YP_003103332.1 CDS Amir_5671 NC_013093.1 6685400 6685795 D KEGG: hypothetical protein; hypothetical protein 6685400..6685795 Actinosynnema mirum DSM 43827 8329878 YP_003103333.1 CDS Amir_5672 NC_013093.1 6686089 6687207 D PFAM: GCN5-related N-acetyltransferase; amino acid- binding ACT domain protein; KEGG: mch:Mchl_1293 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 6686089..6687207 Actinosynnema mirum DSM 43827 8329879 YP_003103334.1 CDS Amir_5673 NC_013093.1 6687607 6688638 D KEGG: vvy:VVA0123 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; LacI family transcriptional regulator 6687607..6688638 Actinosynnema mirum DSM 43827 8329880 YP_003103335.1 CDS Amir_5674 NC_013093.1 6689046 6691562 R PFAM: protein of unknown function DUF214; KEGG: aeh:Mlg_1312 hypothetical protein; hypothetical protein complement(6689046..6691562) Actinosynnema mirum DSM 43827 8329881 YP_003103336.1 CDS Amir_5675 NC_013093.1 6691562 6692314 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: aba:Acid345_0970 ABC transporter, ATPase subunit; ABC transporter complement(6691562..6692314) Actinosynnema mirum DSM 43827 8329882 YP_003103337.1 CDS Amir_5676 NC_013093.1 6692533 6695394 R PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; ATPase AAA; KEGG: rlt:Rleg2_5436 transcriptional regulator, LuxR family; LuxR family transcriptional regulator complement(6692533..6695394) Actinosynnema mirum DSM 43827 8329883 YP_003103338.1 CDS Amir_5677 NC_013093.1 6695531 6698428 R PFAM: transcriptional activator domain; TPR repeat- containing protein; NB-ARC domain protein; transcriptional regulator domain protein; SMART: hypothetical protein; KEGG: scl:sce3550 hypothetical protein; SARP family transcriptional regulator complement(6695531..6698428) Actinosynnema mirum DSM 43827 8329884 YP_003103339.1 CDS Amir_5678 NC_013093.1 6698964 6699629 R PFAM: hypothetical protein; KEGG: ssn:SSON_2375 hypothetical protein; hypothetical protein complement(6698964..6699629) Actinosynnema mirum DSM 43827 8329885 YP_003103340.1 CDS Amir_5679 NC_013093.1 6699936 6700127 R PFAM: protein of unknown function DUF397; hypothetical protein complement(6699936..6700127) Actinosynnema mirum DSM 43827 8329886 YP_003103341.1 CDS Amir_5680 NC_013093.1 6700146 6700994 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator complement(6700146..6700994) Actinosynnema mirum DSM 43827 8329887 YP_003103342.1 CDS Amir_5681 NC_013093.1 6701169 6701549 D hypothetical protein 6701169..6701549 Actinosynnema mirum DSM 43827 8329888 YP_003103343.1 CDS Amir_5682 NC_013093.1 6701944 6704163 D PFAM: carbonic anhydrase; sulphate transporter; xanthine/uracil/vitamin C permease; KEGG: mxa:MXAN_4784 inorganic anion transporter, sulfate permease (SulP) family; carbonate dehydratase 6701944..6704163 Actinosynnema mirum DSM 43827 8329889 YP_003103344.1 CDS Amir_5683 NC_013093.1 6704244 6705683 R TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: bsu:BSU23860 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase complement(6704244..6705683) Actinosynnema mirum DSM 43827 8329890 YP_003103345.1 CDS Amir_5684 NC_013093.1 6705946 6707874 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: hypothetical protein; ECF subfamily RNA polymerase sigma-24 subunit complement(6705946..6707874) Actinosynnema mirum DSM 43827 8329891 YP_003103346.1 CDS Amir_5685 NC_013093.1 6707962 6709350 D PFAM: pyridoxal-dependent decarboxylase; KEGG: aba:Acid345_2160 aromatic-L-amino-acid decarboxylase; Aromatic-L-amino-acid decarboxylase 6707962..6709350 Actinosynnema mirum DSM 43827 8329892 YP_003103347.1 CDS Amir_5686 NC_013093.1 6709518 6710450 R KEGG: met:M446_5500 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; acyl-CoA thioesterase II complement(6709518..6710450) Actinosynnema mirum DSM 43827 8329893 YP_003103348.1 CDS Amir_5687 NC_013093.1 6710466 6711890 R KEGG: gur:Gura_4409 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; pyruvate kinase complement(6710466..6711890) Actinosynnema mirum DSM 43827 8329894 YP_003103349.1 CDS Amir_5688 NC_013093.1 6711976 6712335 D PFAM: VanZ family protein; KEGG: jan:Jann_0771 VanZ like protein; VanZ family protein 6711976..6712335 Actinosynnema mirum DSM 43827 8329895 YP_003103350.1 CDS Amir_5689 NC_013093.1 6712420 6713076 R KEGG: hch:HCH_00125 hypothetical protein; hypothetical protein complement(6712420..6713076) Actinosynnema mirum DSM 43827 8329896 YP_003103351.1 CDS Amir_5690 NC_013093.1 6713371 6714273 R hypothetical protein complement(6713371..6714273) Actinosynnema mirum DSM 43827 8329897 YP_003103352.1 CDS Amir_5691 NC_013093.1 6714380 6715741 R KEGG: xau:Xaut_0919 leucine-rich repeat-containing protein; hypothetical protein complement(6714380..6715741) Actinosynnema mirum DSM 43827 8329898 YP_003103353.1 CDS Amir_5692 NC_013093.1 6716066 6717568 R TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: sus:Acid_3815 glutamate synthase (NADH) small subunit; glutamate synthase, NADH/NADPH, small subunit complement(6716066..6717568) Actinosynnema mirum DSM 43827 8329899 YP_003103354.1 CDS Amir_5693 NC_013093.1 6717561 6722099 R PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin); glutamate synthase (ferredoxin) complement(6717561..6722099) Actinosynnema mirum DSM 43827 8329900 YP_003103355.1 CDS Amir_5694 NC_013093.1 6723006 6724376 R PFAM: sodium:dicarboxylate symporter; KEGG: gur:Gura_0381 sodium:dicarboxylate symporter; sodium:dicarboxylate symporter complement(6723006..6724376) Actinosynnema mirum DSM 43827 8329901 YP_003103356.1 CDS Amir_5695 NC_013093.1 6724957 6725883 D TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: sfu:Sfum_3723 TRAP transporter solute receptor, TAXI family; TRAP transporter solute receptor, TAXI family 6724957..6725883 Actinosynnema mirum DSM 43827 8329902 YP_003103357.1 CDS Amir_5696 NC_013093.1 6726232 6727599 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_0328 ATPase domain-containing protein; histidine kinase complement(6726232..6727599) Actinosynnema mirum DSM 43827 8329903 YP_003103358.1 CDS Amir_5697 NC_013093.1 6727708 6728274 D KEGG: scl:sce7916 hypothetical protein; hypothetical protein 6727708..6728274 Actinosynnema mirum DSM 43827 8329904 YP_003103359.1 CDS Amir_5698 NC_013093.1 6728338 6729006 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: ade:Adeh_3856 two component transcriptional regulator; winged helix family two component transcriptional regulator complement(6728338..6729006) Actinosynnema mirum DSM 43827 8329905 YP_003103360.1 CDS Amir_5699 NC_013093.1 6729013 6730128 R TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; KEGG: bha:BH3589 prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase complement(6729013..6730128) Actinosynnema mirum DSM 43827 8329906 YP_003103361.1 CDS Amir_5700 NC_013093.1 6730301 6731086 R KEGG: acp:A2cp1_4201 tryptophan synthase, alpha subunit; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain; tryptophan synthase subunit alpha complement(6730301..6731086) Actinosynnema mirum DSM 43827 8329907 YP_003103362.1 CDS Amir_5701 NC_013093.1 6731083 6732318 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(6731083..6732318) Actinosynnema mirum DSM 43827 8329908 YP_003103363.1 CDS trpC NC_013093.1 6732330 6733145 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase complement(6732330..6733145) Actinosynnema mirum DSM 43827 8329909 YP_003103364.1 CDS Amir_5703 NC_013093.1 6733361 6733993 R KEGG: azo:azo0239 hypothetical protein; hypothetical protein complement(6733361..6733993) Actinosynnema mirum DSM 43827 8329910 YP_003103365.1 CDS Amir_5704 NC_013093.1 6734079 6735620 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(6734079..6735620) Actinosynnema mirum DSM 43827 8329911 YP_003103366.1 CDS Amir_5705 NC_013093.1 6735739 6736401 D PFAM: regulatory protein TetR; KEGG: mlo:mlr3851 TetR family transcriptional regulator; TetR family transcriptional regulator 6735739..6736401 Actinosynnema mirum DSM 43827 8329912 YP_003103367.1 CDS Amir_5706 NC_013093.1 6736326 6736700 R PFAM: phosphoribosyl-AMP cyclohydrolase; KEGG: mag:amb2307 phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-AMP cyclohydrolase complement(6736326..6736700) Actinosynnema mirum DSM 43827 8329913 YP_003103368.1 CDS Amir_5707 NC_013093.1 6736700 6737062 R KEGG: pen:PSEEN4801 sensor histidine kinase; hypothetical protein complement(6736700..6737062) Actinosynnema mirum DSM 43827 8329914 YP_003103369.1 CDS Amir_5708 NC_013093.1 6737062 6737835 R TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; KEGG: rce:RC1_3299 imidazoleglycerol phosphate synthase, cyclase subunit; imidazoleglycerol phosphate synthase, cyclase subunit complement(6737062..6737835) Actinosynnema mirum DSM 43827 8329915 YP_003103370.1 CDS Amir_5709 NC_013093.1 6737946 6738335 R TIGRFAM: death-on-curing family protein; PFAM: filamentation induced by cAMP protein Fic; KEGG: pla:Plav_1338 death-on-curing family protein; death-on-curing family protein complement(6737946..6738335) Actinosynnema mirum DSM 43827 8329916 YP_003103371.1 CDS Amir_5710 NC_013093.1 6738459 6738827 D hypothetical protein 6738459..6738827 Actinosynnema mirum DSM 43827 8329917 YP_003103372.1 CDS Amir_5711 NC_013093.1 6738866 6739588 D PFAM: Clp domain protein; KEGG: Os12g0230100; hypothetical protein; K03696 ATP-dependent Clp protease ATP-binding subunit ClpC; Clp domain-containing protein 6738866..6739588 Actinosynnema mirum DSM 43827 8329918 YP_003103373.1 CDS Amir_5712 NC_013093.1 6739551 6740285 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A complement(6739551..6740285) Actinosynnema mirum DSM 43827 8329919 YP_003103374.1 CDS Amir_5713 NC_013093.1 6740335 6740967 R TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; KEGG: xau:Xaut_2291 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit complement(6740335..6740967) Actinosynnema mirum DSM 43827 8329920 YP_003103375.1 CDS Amir_5714 NC_013093.1 6740978 6741466 R hypothetical protein complement(6740978..6741466) Actinosynnema mirum DSM 43827 8329921 YP_003103376.1 CDS Amir_5715 NC_013093.1 6741504 6742394 R PFAM: transketolase; transketolase; KEGG: rpe:RPE_1518 transketolase, central region; transketolase complement(6741504..6742394) Actinosynnema mirum DSM 43827 8329922 YP_003103377.1 CDS Amir_5716 NC_013093.1 6742391 6743077 R PFAM: transketolase; KEGG: bja:blr5426 transketolase; transketolase complement(6742391..6743077) Actinosynnema mirum DSM 43827 8329923 YP_003103378.1 CDS Amir_5717 NC_013093.1 6743101 6743592 D KEGG: aav:Aave_2276 transcriptional regulator, MerR family; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR; MerR family transcriptional regulator 6743101..6743592 Actinosynnema mirum DSM 43827 8329924 YP_003103379.1 CDS Amir_5718 NC_013093.1 6743603 6744127 D PFAM: phosphotransferase KptA/Tpt1; KEGG: rle:RL2607 RNA 2'-phosphotransferase; phosphotransferase KptA/Tpt1 6743603..6744127 Actinosynnema mirum DSM 43827 8329925 YP_003103380.1 CDS Amir_5719 NC_013093.1 6744177 6744317 R hypothetical protein complement(6744177..6744317) Actinosynnema mirum DSM 43827 8329926 YP_003103381.1 CDS Amir_5720 NC_013093.1 6744333 6744935 R PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: acr:Acry_1413 imidazoleglycerol-phosphate dehydratase; imidazoleglycerol-phosphate dehydratase complement(6744333..6744935) Actinosynnema mirum DSM 43827 8329927 YP_003103382.1 CDS Amir_5721 NC_013093.1 6744932 6746083 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(6744932..6746083) Actinosynnema mirum DSM 43827 8329928 YP_003103383.1 CDS hisD NC_013093.1 6746080 6747396 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(6746080..6747396) Actinosynnema mirum DSM 43827 8329929 YP_003103384.1 CDS Amir_5723 NC_013093.1 6747591 6748910 D PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; KEGG: bba:Bd3234 carboxypeptidase T precursor; peptidase M14 carboxypeptidase A 6747591..6748910 Actinosynnema mirum DSM 43827 8329930 YP_003103385.1 CDS Amir_5724 NC_013093.1 6749030 6750211 R PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce8911 class-V aminotransferase; class V aminotransferase complement(6749030..6750211) Actinosynnema mirum DSM 43827 8329931 YP_003103386.1 CDS Amir_5725 NC_013093.1 6750196 6751755 R PFAM: extracellular solute-binding protein family 5; KEGG: ses:SARI_01727 hypothetical protein; family 5 extracellular solute-binding protein complement(6750196..6751755) Actinosynnema mirum DSM 43827 8329932 YP_003103387.1 CDS Amir_5726 NC_013093.1 6751772 6752551 D PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eta:ETA_23610 hydrolase; nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase 6751772..6752551 Actinosynnema mirum DSM 43827 8329933 YP_003103388.1 CDS Amir_5727 NC_013093.1 6752703 6753140 D PFAM: PRC-barrel domain protein; KEGG: atc:AGR_C_723 hypothetical protein; PRC-barrel domain-containing protein 6752703..6753140 Actinosynnema mirum DSM 43827 8329934 YP_003103389.1 CDS Amir_5728 NC_013093.1 6753345 6754208 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(6753345..6754208) Actinosynnema mirum DSM 43827 8329935 YP_003103390.1 CDS Amir_5729 NC_013093.1 6754288 6755904 R KEGG: sus:Acid_7341 L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; L-aspartate oxidase complement(6754288..6755904) Actinosynnema mirum DSM 43827 8329936 YP_003103391.1 CDS Amir_5730 NC_013093.1 6755901 6756920 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(6755901..6756920) Actinosynnema mirum DSM 43827 8329937 YP_003103392.1 CDS Amir_5731 NC_013093.1 6756994 6757683 D PFAM: NUDIX hydrolase; KEGG: dal:Dalk_4948 NUDIX hydrolase; NUDIX hydrolase 6756994..6757683 Actinosynnema mirum DSM 43827 8329938 YP_003103393.1 CDS Amir_5732 NC_013093.1 6757680 6758360 D PFAM: peptidase S16 lon domain protein; SMART: peptidase S16 lon domain protein; KEGG: pau:PA14_11940 hypothetical protein; peptidase S16 lon domain-containing protein 6757680..6758360 Actinosynnema mirum DSM 43827 8329939 YP_003103394.1 CDS Amir_5734 NC_013093.1 6759781 6761052 D PFAM: major facilitator superfamily MFS_1; General substrate transporter; KEGG: cti:RALTA_B1248 muconolactone transporter; major facilitator superfamily MFS_1; major facilitator superfamily protein 6759781..6761052 Actinosynnema mirum DSM 43827 8329941 YP_003103395.1 CDS Amir_5735 NC_013093.1 6761141 6761896 D PFAM: protein of unknown function DUF1445; KEGG: pde:Pden_0321 hypothetical protein; hypothetical protein 6761141..6761896 Actinosynnema mirum DSM 43827 8329942 YP_003103396.1 CDS Amir_5736 NC_013093.1 6761903 6763198 R KEGG: trans-sialidase; hypothetical protein complement(6761903..6763198) Actinosynnema mirum DSM 43827 8329943 YP_003103397.1 CDS Amir_5737 NC_013093.1 6763292 6763489 R hypothetical protein complement(6763292..6763489) Actinosynnema mirum DSM 43827 8329944 YP_003103398.1 CDS Amir_5738 NC_013093.1 6763486 6764529 R catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase complement(6763486..6764529) Actinosynnema mirum DSM 43827 8329945 YP_003103399.1 CDS Amir_5739 NC_013093.1 6764613 6765341 R TIGRFAM: dethiobiotin synthase; KEGG: ade:Adeh_0070 dethiobiotin synthase; dethiobiotin synthase complement(6764613..6765341) Actinosynnema mirum DSM 43827 8329946 YP_003103400.1 CDS Amir_5740 NC_013093.1 6765390 6765635 D PFAM: glutaredoxin; KEGG: mno:Mnod_5953 glutaredoxin 3; glutaredoxin 6765390..6765635 Actinosynnema mirum DSM 43827 8329947 YP_003103401.1 CDS Amir_5741 NC_013093.1 6765641 6766285 D KEGG: MFS transporter; hypothetical protein 6765641..6766285 Actinosynnema mirum DSM 43827 8329948 YP_003103402.1 CDS Amir_5742 NC_013093.1 6766265 6767548 R TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: scl:sce0693 adenosylmethionine--8-amino-7- oxononanoate transaminase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(6766265..6767548) Actinosynnema mirum DSM 43827 8329949 YP_003103403.1 CDS dnaE NC_013093.1 6768297 6771827 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(6768297..6771827) Actinosynnema mirum DSM 43827 8329950 YP_003103404.1 CDS Amir_5744 NC_013093.1 6772069 6772941 D KEGG: GA25950 gene product from transcript GA25950- RA; hypothetical protein 6772069..6772941 Actinosynnema mirum DSM 43827 8329951 YP_003103405.1 CDS Amir_5745 NC_013093.1 6773314 6774567 D TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bce:BC0204 bicyclomycin resistance protein; Bcr/CflA subfamily drug resistance transporter 6773314..6774567 Actinosynnema mirum DSM 43827 8329952 YP_003103406.1 CDS Amir_5746 NC_013093.1 6774660 6775592 R KEGG: gsu:GSU0082 ribosomal large subunit pseudouridine synthase D; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; RluA family pseudouridine synthase complement(6774660..6775592) Actinosynnema mirum DSM 43827 8329953 YP_003103407.1 CDS Amir_5747 NC_013093.1 6775589 6776353 R TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; KEGG: sde:Sde_2565 signal peptidase II; lipoprotein signal peptidase complement(6775589..6776353) Actinosynnema mirum DSM 43827 8329954 YP_003103408.1 CDS Amir_5748 NC_013093.1 6776394 6777752 R PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: scl:sce1210 hypothetical protein; class V aminotransferase complement(6776394..6777752) Actinosynnema mirum DSM 43827 8329955 YP_003103409.1 CDS Amir_5749 NC_013093.1 6778117 6779595 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(6778117..6779595) Actinosynnema mirum DSM 43827 8329956 YP_003103410.1 CDS Amir_5751 NC_013093.1 6781173 6781736 D PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMa1660 hypothetical protein; GCN5-like N-acetyltransferase 6781173..6781736 Actinosynnema mirum DSM 43827 8329958 YP_003103411.1 CDS Amir_5752 NC_013093.1 6781872 6782144 R PFAM: protein of unknown function DUF167; KEGG: scl:sce8156 hypothetical protein; hypothetical protein complement(6781872..6782144) Actinosynnema mirum DSM 43827 8329959 YP_003103412.1 CDS ileS NC_013093.1 6782243 6785356 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase complement(6782243..6785356) Actinosynnema mirum DSM 43827 8329960 YP_003103413.1 CDS Amir_5754 NC_013093.1 6785621 6786352 R KEGG: col-102; COllagen; hypothetical protein complement(6785621..6786352) Actinosynnema mirum DSM 43827 8329961 YP_003103414.1 CDS Amir_5755 NC_013093.1 6786401 6787222 R PFAM: DivIVA family protein; KEGG: hypothetical protein; DivIVA family protein complement(6786401..6787222) Actinosynnema mirum DSM 43827 8329962 YP_003103415.1 CDS Amir_5756 NC_013093.1 6787268 6787552 R PFAM: protein of unknown function YGGT; hypothetical protein complement(6787268..6787552) Actinosynnema mirum DSM 43827 8329963 YP_003103416.1 CDS Amir_5757 NC_013093.1 6787573 6788220 R PFAM: protein of unknown function DUF552; KEGG: bha:BH2549 hypothetical protein; hypothetical protein complement(6787573..6788220) Actinosynnema mirum DSM 43827 8329964 YP_003103417.1 CDS Amir_5758 NC_013093.1 6788288 6788983 R PFAM: alanine racemase domain protein; KEGG: pag:PLES_03921 PLP dependent enzyme; alanine racemase domain-containing protein complement(6788288..6788983) Actinosynnema mirum DSM 43827 8329965 YP_003103418.1 CDS Amir_5759 NC_013093.1 6788980 6789666 R PFAM: protein of unknown function DUF152; KEGG: tgr:Tgr7_0816 protein of unknown function DUF152; hypothetical protein complement(6788980..6789666) Actinosynnema mirum DSM 43827 8329966 YP_003103419.1 CDS Amir_5760 NC_013093.1 6789842 6791056 R TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ domain protein; KEGG: bat:BAS3757 cell division protein FtsZ; cell division protein FtsZ complement(6789842..6791056) Actinosynnema mirum DSM 43827 8329967 YP_003103420.1 CDS Amir_5761 NC_013093.1 6791578 6792300 R PFAM: polypeptide-transport-associated domain protein FtsQ-type; cell division protein FtsQ; KEGG: ade:Adeh_3776 cell division protein FtsQ; polypeptide-transport-associated protein domain-containing protein FtsQ-type complement(6791578..6792300) Actinosynnema mirum DSM 43827 8329968 YP_003103421.1 CDS murC NC_013093.1 6792297 6793697 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(6792297..6793697) Actinosynnema mirum DSM 43827 8329969 YP_003103422.1 CDS Amir_5763 NC_013093.1 6793694 6794764 R KEGG: aba:Acid345_3629 UDP-N-acetylglucosamine--N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase; TIGRFAM:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase; PFAM: glycosyltransferase 28 domain; glycosyl transferase family 28; UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase complement(6793694..6794764) Actinosynnema mirum DSM 43827 8329970 YP_003103423.1 CDS Amir_5764 NC_013093.1 6795220 6796683 R TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: bce:BC3911 stage V sporulation protein E; cell division protein FtsW complement(6795220..6796683) Actinosynnema mirum DSM 43827 8329971 YP_003103424.1 CDS Amir_5765 NC_013093.1 6796793 6798007 R KEGG: rec:RHECIAT_PA0000107 hypothetical protein; hypothetical protein complement(6796793..6798007) Actinosynnema mirum DSM 43827 8329972 YP_003103425.1 CDS Amir_5766 NC_013093.1 6798009 6798470 R hypothetical protein complement(6798009..6798470) Actinosynnema mirum DSM 43827 8329973 YP_003103426.1 CDS Amir_5767 NC_013093.1 6798490 6799767 R KEGG: sfu:Sfum_1001 FAD dependent oxidoreductase; FAD-dependent dehydrogenase-like protein complement(6798490..6799767) Actinosynnema mirum DSM 43827 8329974 YP_003103427.1 CDS Amir_5768 NC_013093.1 6799922 6801274 R TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: scl:sce1662 UDP-N-acetylmuramoylalanine-D- glutamate ligase; UDP-N-acetylmuramoylalanine/D-glutamate ligase complement(6799922..6801274) Actinosynnema mirum DSM 43827 8329975 YP_003103428.1 CDS mraY NC_013093.1 6801277 6802365 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(6801277..6802365) Actinosynnema mirum DSM 43827 8329976 YP_003103429.1 CDS Amir_5770 NC_013093.1 6802362 6803834 R TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-di aminopimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: aeh:Mlg_2197 UDP-N-acetylmuramoyl-tripeptide-- D-alanyl-D-alanine ligase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanylligase complement(6802362..6803834) Actinosynnema mirum DSM 43827 8329977 YP_003103430.1 CDS Amir_5771 NC_013093.1 6803831 6805414 R TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: ade:Adeh_3766 UDP-N-acetylmuramoylalanyl-D- glutamate--2,6-diaminopimelate ligase; UDP-N-acetylmuramyl-tripeptide synthetase complement(6803831..6805414) Actinosynnema mirum DSM 43827 8329978 YP_003103431.1 CDS Amir_5772 NC_013093.1 6805477 6807384 R PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ppd:Ppro_3295 peptidoglycan glycosyltransferase; peptidoglycan glycosyltransferase complement(6805477..6807384) Actinosynnema mirum DSM 43827 8329979 YP_003103432.1 CDS Amir_5773 NC_013093.1 6807922 6808683 R KEGG: hypothetical protein; hypothetical protein complement(6807922..6808683) Actinosynnema mirum DSM 43827 8329980 YP_003103433.1 CDS mraW NC_013093.1 6808680 6809630 R TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: gbm:Gbem_0483 S-adenosyl-methyltransferase MraW; S-adenosyl-methyltransferase MraW complement(6808680..6809630) Actinosynnema mirum DSM 43827 8329981 YP_003103434.1 CDS Amir_5775 NC_013093.1 6810010 6810441 R TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: bha:BH2576 cell division protein MraZ; MraZ protein complement(6810010..6810441) Actinosynnema mirum DSM 43827 8329982 YP_003103435.1 CDS Amir_5776 NC_013093.1 6810934 6811998 D PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: bha:BH0604 methanol dehydrogenase regulatory protein; ATPase 6810934..6811998 Actinosynnema mirum DSM 43827 8329983 YP_003103436.1 CDS Amir_5777 NC_013093.1 6812000 6813289 D PFAM: protein of unknown function DUF58; KEGG: gur:Gura_0188 hypothetical protein; hypothetical protein 6812000..6813289 Actinosynnema mirum DSM 43827 8329984 YP_003103437.1 CDS Amir_5778 NC_013093.1 6813290 6815737 D PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: aba:Acid345_2146 transglutaminase-like; transglutaminase domain-containing protein 6813290..6815737 Actinosynnema mirum DSM 43827 8329985 YP_003103438.1 CDS Amir_5779 NC_013093.1 6816367 6816753 R hypothetical protein complement(6816367..6816753) Actinosynnema mirum DSM 43827 8329986 YP_003103439.1 CDS Amir_5780 NC_013093.1 6817206 6818273 R KEGG: GF24314 gene product from transcript GF24314- RA; hypothetical protein complement(6817206..6818273) Actinosynnema mirum DSM 43827 8329987 YP_003103440.1 CDS Amir_5781 NC_013093.1 6818311 6819327 R KEGG: similar to keratinocytes proline-rich protein; hypothetical protein complement(6818311..6819327) Actinosynnema mirum DSM 43827 8329988 YP_003103441.1 CDS Amir_5782 NC_013093.1 6819539 6819802 R hypothetical protein complement(6819539..6819802) Actinosynnema mirum DSM 43827 8329989 YP_003103442.1 CDS Amir_5783 NC_013093.1 6819882 6820520 R PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; cyclic nucleotide- binding; KEGG: lch:Lcho_0755 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator complement(6819882..6820520) Actinosynnema mirum DSM 43827 8329990 YP_003103443.1 CDS Amir_5784 NC_013093.1 6820903 6822195 R PFAM: UMUC domain protein DNA-repair protein; KEGG: acp:A2cp1_0159 DNA-directed DNA polymerase; DNA-directed DNA polymerase complement(6820903..6822195) Actinosynnema mirum DSM 43827 8329991 YP_003103444.1 CDS Amir_5785 NC_013093.1 6822244 6823335 R PFAM: amidohydrolase 2; KEGG: hypothetical protein; amidohydrolase 2 complement(6822244..6823335) Actinosynnema mirum DSM 43827 8329992 YP_003103445.1 CDS Amir_5786 NC_013093.1 6823374 6824702 D PFAM: glutamine synthetase catalytic region; KEGG: pag:PLES_59041 glutamine synthetase; glutamine synthetase 6823374..6824702 Actinosynnema mirum DSM 43827 8329993 YP_003103446.1 CDS Amir_5787 NC_013093.1 6824722 6825315 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rpb:RPB_3555 RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit complement(6824722..6825315) Actinosynnema mirum DSM 43827 8329994 YP_003103447.1 CDS Amir_5788 NC_013093.1 6825326 6826057 R PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: ank:AnaeK_0691 methyltransferase type 11; type 12 methyltransferase complement(6825326..6826057) Actinosynnema mirum DSM 43827 8329995 YP_003103448.1 CDS Amir_5789 NC_013093.1 6826092 6826928 D PFAM: cobyrinic acid ac-diamide synthase; KEGG: gox:GOX1063 chromosome partitioning protein ParA; cobyrinic acid ac-diamide synthase 6826092..6826928 Actinosynnema mirum DSM 43827 8329996 YP_003103449.1 CDS Amir_5790 NC_013093.1 6826950 6827747 D PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; KEGG: afw:Anae109_1725 DNA-(apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyase 6826950..6827747 Actinosynnema mirum DSM 43827 8329997 YP_003103450.1 CDS Amir_5791 NC_013093.1 6827758 6828786 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 6827758..6828786 Actinosynnema mirum DSM 43827 8329998 YP_003103451.1 CDS Amir_5792 NC_013093.1 6828793 6829443 R PFAM: regulatory protein TetR; KEGG: rso:RS05498 transcription regulator protein; TetR family transcriptional regulator complement(6828793..6829443) Actinosynnema mirum DSM 43827 8329999 YP_003103452.1 CDS Amir_5793 NC_013093.1 6829547 6830260 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bpy:Bphyt_6660 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 6829547..6830260 Actinosynnema mirum DSM 43827 8330000 YP_003103453.1 CDS Amir_5794 NC_013093.1 6830296 6831543 R PFAM: xanthine/uracil/vitamin C permease; KEGG: bmv:BMASAVP1_A3006 uracil-xanthine permease; xanthine/uracil/vitamin C permease complement(6830296..6831543) Actinosynnema mirum DSM 43827 8330001 YP_003103454.1 CDS Amir_5795 NC_013093.1 6832041 6832829 R KEGG: jan:Jann_1769 mucin-associated surface protein; hypothetical protein complement(6832041..6832829) Actinosynnema mirum DSM 43827 8330002 YP_003103455.1 CDS Amir_5796 NC_013093.1 6832844 6833710 R PFAM: PspA/IM30 family protein; KEGG: GG12650 gene product from transcript GG12650- RA; phage shock protein PspA complement(6832844..6833710) Actinosynnema mirum DSM 43827 8330003 YP_003103456.1 CDS Amir_5797 NC_013093.1 6833998 6834414 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pde:Pden_1785 helix-turn-helix domain protein; helix-turn-helix domain-containing protein complement(6833998..6834414) Actinosynnema mirum DSM 43827 8330004 YP_003103457.1 CDS Amir_5798 NC_013093.1 6834580 6835191 R PFAM: CinA domain protein; KEGG: hypothetical protein; CinA domain-containing protein complement(6834580..6835191) Actinosynnema mirum DSM 43827 8330005 YP_003103458.1 CDS Amir_5799 NC_013093.1 6835188 6835772 R TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bha:BH2386 phosphatidylglycerophosphate synthase; CDP-diacylglycerol/glycerol-3-phosphate3- phosphatidyltransferase complement(6835188..6835772) Actinosynnema mirum DSM 43827 8330006 YP_003103459.1 CDS Amir_5800 NC_013093.1 6835769 6837178 R KEGG: ank:AnaeK_0100 MiaB-like tRNA modifying enzyme YliG; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: Protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying protein YliG complement(6835769..6837178) Actinosynnema mirum DSM 43827 8330007 YP_003103460.1 CDS Amir_5801 NC_013093.1 6837451 6837951 D catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase 6837451..6837951 Actinosynnema mirum DSM 43827 8330008 YP_003103461.1 CDS Amir_5802 NC_013093.1 6838066 6838920 D SMART: regulatory protein MerR; KEGG: bmn:BMA10247_A1013 MerR family transcriptional regulator; MerR family transcriptional regulator 6838066..6838920 Actinosynnema mirum DSM 43827 8330009 YP_003103462.1 CDS Amir_5803 NC_013093.1 6839066 6839521 D PFAM: Prokaryotic phospholipase A2; KEGG: hypothetical protein; phospholipase A2 6839066..6839521 Actinosynnema mirum DSM 43827 8330010 YP_003103463.1 CDS Amir_5804 NC_013093.1 6839532 6842093 R PFAM: cell divisionFtsK/SpoIIIE; KEGG: bha:BH2395 hypothetical protein; cell division protein FtsK/SpoIIIE complement(6839532..6842093) Actinosynnema mirum DSM 43827 8330011 YP_003103464.1 CDS Amir_5805 NC_013093.1 6842226 6843032 D PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: dde:Dde_1136 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase 6842226..6843032 Actinosynnema mirum DSM 43827 8330012 YP_003103465.1 CDS Amir_5806 NC_013093.1 6843154 6844833 R PFAM: beta-lactamase domain protein; RNA- metabolising metallo-beta-lactamase; KEGG: gme:Gmet_0366 hypothetical protein; beta-lactamase domain-containing protein complement(6843154..6844833) Actinosynnema mirum DSM 43827 8330013 YP_003103466.1 CDS Amir_5807 NC_013093.1 6844830 6845726 R KEGG: bha:BH2399 dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; dihydrodipicolinate synthase complement(6844830..6845726) Actinosynnema mirum DSM 43827 8330014 YP_003103467.1 CDS Amir_5808 NC_013093.1 6845764 6846384 R hypothetical protein complement(6845764..6846384) Actinosynnema mirum DSM 43827 8330015 YP_003103468.1 CDS Amir_5809 NC_013093.1 6846455 6847918 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: sus:Acid_3693 serine/threonine protein kinase; serine/threonine protein kinase complement(6846455..6847918) Actinosynnema mirum DSM 43827 8330016 YP_003103469.1 CDS thyX NC_013093.1 6848385 6849137 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(6848385..6849137) Actinosynnema mirum DSM 43827 8330018 YP_003103470.1 CDS Amir_5812 NC_013093.1 6849368 6849925 D PFAM: HicB family protein; KEGG: GI22065 gene product from transcript GI22065- RA; HicB family protein 6849368..6849925 Actinosynnema mirum DSM 43827 8330019 YP_003103471.1 CDS Amir_5813 NC_013093.1 6849947 6850840 D KEGG: aba:Acid345_3530 hypothetical protein; hypothetical protein 6849947..6850840 Actinosynnema mirum DSM 43827 8330020 YP_003103472.1 CDS Amir_5814 NC_013093.1 6851015 6851602 R PFAM: regulatory protein TetR; KEGG: bja:bll5689 transcriptional regulatory protein; TetR family transcriptional regulator complement(6851015..6851602) Actinosynnema mirum DSM 43827 8330021 YP_003103473.1 CDS Amir_5816 NC_013093.1 6853486 6854484 R PFAM: aldo/keto reductase; KEGG: rlt:Rleg2_2710 aldo/keto reductase; aldo/keto reductase complement(6853486..6854484) Actinosynnema mirum DSM 43827 8330023 YP_003103474.1 CDS Amir_5817 NC_013093.1 6854561 6855781 R PFAM: protein of unknown function DUF1006; KEGG: pae:PA2844 hypothetical protein; hypothetical protein complement(6854561..6855781) Actinosynnema mirum DSM 43827 8330024 YP_003103475.1 CDS Amir_5818 NC_013093.1 6855837 6856403 D PFAM: GCN5-related N-acetyltransferase; KEGG: bac:BamMC406_4804 GCN5-related N- acetyltransferase; GCN5-like N-acetyltransferase 6855837..6856403 Actinosynnema mirum DSM 43827 8330025 YP_003103476.1 CDS Amir_5819 NC_013093.1 6856411 6856914 D hypothetical protein 6856411..6856914 Actinosynnema mirum DSM 43827 8330026 YP_003103477.1 CDS Amir_5820 NC_013093.1 6856993 6857445 R hypothetical protein complement(6856993..6857445) Actinosynnema mirum DSM 43827 8330027 YP_003103478.1 CDS Amir_5821 NC_013093.1 6857442 6858149 R KEGG: bcz:BCZK1415 dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase complement(6857442..6858149) Actinosynnema mirum DSM 43827 8330028 YP_003103479.1 CDS Amir_5822 NC_013093.1 6858206 6859591 R PFAM: peptidase M16 domain protein; KEGG: gur:Gura_1907 peptidase M16 domain-containing protein; peptidase M16 domain-containing protein complement(6858206..6859591) Actinosynnema mirum DSM 43827 8330029 YP_003103480.1 CDS Amir_5823 NC_013093.1 6859588 6861831 R KEGG: ilo:IL0964 polynucleotide phosphorylase/polyadenylase; TIGRFAM: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; RNA binding S1 domain protein; Exoribonuclease, phosphorolytic domain 2; KH type 1 domain protein; SMART: RNA binding S1 domain protein; KH domain protein; polynucleotide phosphorylase/polyadenylase complement(6859588..6861831) Actinosynnema mirum DSM 43827 8330030 YP_003103481.1 CDS Amir_5824 NC_013093.1 6862077 6862346 R TIGRFAM: ribosomal protein S15; PFAM: ribosomal protein S15; KEGG: gsu:GSU1592 30S ribosomal protein S15; 30S ribosomal protein S15 complement(6862077..6862346) Actinosynnema mirum DSM 43827 8330031 YP_003103482.1 CDS Amir_5825 NC_013093.1 6862472 6862933 R TIGRFAM: 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; KEGG: scl:sce5087 hypothetical protein; 2'-5' RNA ligase complement(6862472..6862933) Actinosynnema mirum DSM 43827 8330032 YP_003103483.1 CDS Amir_5826 NC_013093.1 6862930 6863409 R KEGG: oan:Oant_1395 ABC transporter; hypothetical protein complement(6862930..6863409) Actinosynnema mirum DSM 43827 8330033 YP_003103484.1 CDS Amir_5827 NC_013093.1 6863510 6864442 R TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; riboflavin kinase; KEGG: dvm:DvMF_1762 riboflavin biosynthesis protein RibF; riboflavin biosynthesis protein RibF complement(6863510..6864442) Actinosynnema mirum DSM 43827 8330034 YP_003103485.1 CDS Amir_5828 NC_013093.1 6865056 6865955 R TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; tRNA pseudouridine synthase II; KEGG: ade:Adeh_1105 tRNA pseudouridine synthase B; tRNA pseudouridine synthase B complement(6865056..6865955) Actinosynnema mirum DSM 43827 8330035 YP_003103486.1 CDS Amir_5829 NC_013093.1 6866028 6867347 R PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_3100 major facilitator transporter; major facilitator superfamily protein complement(6866028..6867347) Actinosynnema mirum DSM 43827 8330036 YP_003103487.1 CDS Amir_5830 NC_013093.1 6867439 6868743 R TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: MATE efflux family protein; MATE efflux family protein complement(6867439..6868743) Actinosynnema mirum DSM 43827 8330037 YP_003103488.1 CDS Amir_5831 NC_013093.1 6868828 6869838 R PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: pca:Pcar_1558 exopolyphosphatase related protein; phosphoesterase RecJ domain-containing protein complement(6868828..6869838) Actinosynnema mirum DSM 43827 8330038 YP_003103489.1 CDS Amir_5832 NC_013093.1 6869849 6870298 R TIGRFAM: ribosome-binding factor A; PFAM: ribosome-binding factor A; KEGG: tcx:Tcr_1124 ribosome-binding factor A; ribosome-binding factor A complement(6869849..6870298) Actinosynnema mirum DSM 43827 8330039 YP_003103490.1 CDS Amir_5833 NC_013093.1 6870318 6870614 R PFAM: protein of unknown function DUF503; KEGG: sus:Acid_5182 hypothetical protein; hypothetical protein complement(6870318..6870614) Actinosynnema mirum DSM 43827 8330040 YP_003103491.1 CDS Amir_5834 NC_013093.1 6870713 6873817 R TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; translation initiation factor IF-2 domain protein; Ras family protein; KEGG: dvm:DvMF_2513 translation initiation factor IF-2; translation initiation factor IF-2 complement(6870713..6873817) Actinosynnema mirum DSM 43827 8330041 YP_003103492.1 CDS nusA NC_013093.1 6874271 6875284 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(6874271..6875284) Actinosynnema mirum DSM 43827 8330043 YP_003103493.1 CDS Amir_5837 NC_013093.1 6875281 6875805 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(6875281..6875805) Actinosynnema mirum DSM 43827 8330044 YP_003103494.1 CDS Amir_5838 NC_013093.1 6875961 6876398 D KEGG: hypothetical protein; hypothetical protein 6875961..6876398 Actinosynnema mirum DSM 43827 8330045 YP_003103495.1 CDS Amir_5839 NC_013093.1 6876395 6876835 D hypothetical protein 6876395..6876835 Actinosynnema mirum DSM 43827 8330046 YP_003103496.1 CDS Amir_5840 NC_013093.1 6877030 6877890 R KEGG: AGAP011399-PA; hypothetical protein complement(6877030..6877890) Actinosynnema mirum DSM 43827 8330047 YP_003103497.1 CDS Amir_5841 NC_013093.1 6877985 6878986 R PFAM: aminotransferase class V; KEGG: acp:A2cp1_4498 aminotransferase class V; class V aminotransferase complement(6877985..6878986) Actinosynnema mirum DSM 43827 8330048 YP_003103498.1 CDS Amir_5842 NC_013093.1 6879088 6879876 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3419 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(6879088..6879876) Actinosynnema mirum DSM 43827 8330049 YP_003103499.1 CDS Amir_5843 NC_013093.1 6879925 6880332 D PFAM: protein of unknown function UPF0047; KEGG: rpe:RPE_0423 protein of unknown function UPF0047; hypothetical protein 6879925..6880332 Actinosynnema mirum DSM 43827 8330050 YP_003103500.1 CDS Amir_5844 NC_013093.1 6880457 6881545 D KEGG: scl:sce6476 hypothetical protein; hypothetical protein 6880457..6881545 Actinosynnema mirum DSM 43827 8330051 YP_003103501.1 CDS Amir_5845 NC_013093.1 6881542 6882228 D hypothetical protein 6881542..6882228 Actinosynnema mirum DSM 43827 8330052 YP_003103502.1 CDS Amir_5846 NC_013093.1 6882225 6882914 D PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ade:Adeh_0672 haloacid dehalogenase-like hydrolase; Haloacid dehalogenase domain-containing protein hydrolase 6882225..6882914 Actinosynnema mirum DSM 43827 8330053 YP_003103503.1 CDS Amir_5847 NC_013093.1 6882984 6884729 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(6882984..6884729) Actinosynnema mirum DSM 43827 8330054 YP_003103504.1 CDS Amir_5848 NC_013093.1 6884926 6885279 D KEGG: rle:RL3033 hypothetical protein; hypothetical protein 6884926..6885279 Actinosynnema mirum DSM 43827 8330055 YP_003103505.1 CDS Amir_5849 NC_013093.1 6885718 6886485 D PFAM: protein of unknown function DUF328; KEGG: sun:SUN_0122 hypothetical protein; hypothetical protein 6885718..6886485 Actinosynnema mirum DSM 43827 8330056 YP_003103506.1 CDS Amir_5850 NC_013093.1 6886907 6887578 D PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: swi:Swit_2706 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 6886907..6887578 Actinosynnema mirum DSM 43827 8330057 YP_003103507.1 CDS Amir_5851 NC_013093.1 6887701 6888429 D PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: gsu:GSU1992 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 6887701..6888429 Actinosynnema mirum DSM 43827 8330058 YP_003103508.1 CDS Amir_5852 NC_013093.1 6888887 6890050 D PFAM: protein of unknown function RIO1; SMART: protein of unknown function RIO1; KEGG: afw:Anae109_3105 protein of unknown function RIO1; hypothetical protein 6888887..6890050 Actinosynnema mirum DSM 43827 8330059 YP_003103509.1 CDS Amir_5853 NC_013093.1 6890931 6892436 D PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: smt:Smal_0480 DEAD/DEAH box helicase domain protein; DEAD/DEAH box helicase domain-containing protein 6890931..6892436 Actinosynnema mirum DSM 43827 8330060 YP_003103510.1 CDS Amir_5854 NC_013093.1 6892754 6893971 R TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cvi:CV_0813 uroporphyrin-III C- methyltransferase; uroporphyrin-III C-methyltransferase complement(6892754..6893971) Actinosynnema mirum DSM 43827 8330061 YP_003103511.1 CDS Amir_5855 NC_013093.1 6894286 6895071 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: similar to trypsin-like proteinase; peptidase S1 and S6 chymotrypsin/Hap complement(6894286..6895071) Actinosynnema mirum DSM 43827 8330062 YP_003103512.1 CDS Amir_5856 NC_013093.1 6895160 6896419 R PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: mag:amb0298 precorrin-3B methylase; cobalamin (vitamin B12) biosynthesis CbiG protein complement(6895160..6896419) Actinosynnema mirum DSM 43827 8330063 YP_003103513.1 CDS Amir_5858 NC_013093.1 6897607 6898740 R PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ppd:Ppro_3231 precorrin-4 C11- methyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase complement(6897607..6898740) Actinosynnema mirum DSM 43827 8330065 YP_003103514.1 CDS Amir_5859 NC_013093.1 6898911 6900308 R TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: gsu:GSU3006 cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase complement(6898911..6900308) Actinosynnema mirum DSM 43827 8330066 YP_003103515.1 CDS Amir_5860 NC_013093.1 6900305 6900919 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(6900305..6900919) Actinosynnema mirum DSM 43827 8330067 YP_003103516.1 CDS Amir_5861 NC_013093.1 6901019 6903061 R KEGG: rso:RS03742 chelatase protein; PFAM: von Willebrand factor type A; magnesium chelatase ChlI subunit; SMART: von Willebrand factor type A; ATPase AAA; magnesium chelatase complement(6901019..6903061) Actinosynnema mirum DSM 43827 8330068 YP_003103517.1 CDS Amir_5862 NC_013093.1 6903317 6904210 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bid:Bind_0032 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(6903317..6904210) Actinosynnema mirum DSM 43827 8330069 YP_003103518.1 CDS Amir_5863 NC_013093.1 6904272 6904940 D PFAM: regulatory protein TetR; KEGG: scl:sce4851 TetR family transcriptional regulator; TetR family transcriptional regulator 6904272..6904940 Actinosynnema mirum DSM 43827 8330070 YP_003103519.1 CDS Amir_5864 NC_013093.1 6905017 6906195 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 6905017..6906195 Actinosynnema mirum DSM 43827 8330071 YP_003103520.1 CDS Amir_5865 NC_013093.1 6906146 6906598 R PFAM: GCN5-related N-acetyltransferase; KEGG: pap:PSPA7_0190 hypothetical protein; GCN5-like N-acetyltransferase complement(6906146..6906598) Actinosynnema mirum DSM 43827 8330072 YP_003103521.1 CDS Amir_5866 NC_013093.1 6906696 6907445 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: similar to oviductin; peptidase S1 and S6 chymotrypsin/Hap complement(6906696..6907445) Actinosynnema mirum DSM 43827 8330073 YP_003103522.1 CDS Amir_5867 NC_013093.1 6907613 6908227 D PFAM: lysine exporter protein (LYSE/YGGA); KEGG: cak:Caul_0349 lysine exporter protein LysE/YggA; lysine exporter protein LysE/YggA 6907613..6908227 Actinosynnema mirum DSM 43827 8330074 YP_003103523.1 CDS Amir_5868 NC_013093.1 6908247 6908978 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: similar to trypsin-like proteinase; peptidase S1 and S6 chymotrypsin/Hap complement(6908247..6908978) Actinosynnema mirum DSM 43827 8330075 YP_003103524.1 CDS Amir_5869 NC_013093.1 6909074 6909817 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: GK19455 gene product from transcript GK19455- RA; peptidase S1 and S6 chymotrypsin/Hap complement(6909074..6909817) Actinosynnema mirum DSM 43827 8330076 YP_003103525.1 CDS Amir_5870 NC_013093.1 6909986 6911020 R PFAM: peptidase M48 Ste24p; KEGG: hypothetical protein; peptidase M48 Ste24p complement(6909986..6911020) Actinosynnema mirum DSM 43827 8330077 YP_003103526.1 CDS Amir_5871 NC_013093.1 6911101 6912030 D PFAM: alpha/beta hydrolase fold; KEGG: abb:ABBFA_001367 alpha/beta hydrolase fold family protein; alpha/beta hydrolase fold protein 6911101..6912030 Actinosynnema mirum DSM 43827 8330078 YP_003103527.1 CDS Amir_5872 NC_013093.1 6912027 6912692 D KEGG: tgr:Tgr7_3169 streptogramin A acetyl transferase; streptogramin A acetyl transferase 6912027..6912692 Actinosynnema mirum DSM 43827 8330079 YP_003103528.1 CDS Amir_5873 NC_013093.1 6912767 6915124 R KEGG: scl:sce5003 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: ATPase AAA; peptidase S16 lon domain protein; ATPase associated with various cellular activities AAA_5; SMART: peptidase S16 lon domain protein; ATPase AAA; ATP-dependent protease La complement(6912767..6915124) Actinosynnema mirum DSM 43827 8330080 YP_003103529.1 CDS Amir_5874 NC_013093.1 6915296 6916096 D PFAM: protein of unknown function DUF574; KEGG: scl:sce6070 hypothetical protein; hypothetical protein 6915296..6916096 Actinosynnema mirum DSM 43827 8330081 YP_003103530.1 CDS Amir_5875 NC_013093.1 6916175 6918115 R PFAM: Patatin; KEGG: acp:A2cp1_0560 thermosensitive mutation transmembrane protein, SuhR; patatin complement(6916175..6918115) Actinosynnema mirum DSM 43827 8330082 YP_003103531.1 CDS Amir_5876 NC_013093.1 6918272 6919069 R PFAM: polysaccharide deacetylase; KEGG: aba:Acid345_4749 polysaccharide deacetylase; polysaccharide deacetylase complement(6918272..6919069) Actinosynnema mirum DSM 43827 8330083 YP_003103532.1 CDS Amir_5877 NC_013093.1 6919203 6919730 D PFAM: PEBP family protein; KEGG: eta:ETA_22690 hypothetical protein; PEBP family protein 6919203..6919730 Actinosynnema mirum DSM 43827 8330084 YP_003103533.1 CDS Amir_5878 NC_013093.1 6919772 6921154 D catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; mycothione reductase 6919772..6921154 Actinosynnema mirum DSM 43827 8330085 YP_003103534.1 CDS Amir_5879 NC_013093.1 6921251 6922588 R PFAM: major facilitator superfamily MFS_1; KEGG: rpi:Rpic_4548 major facilitator superfamily MFS_1; major facilitator superfamily protein complement(6921251..6922588) Actinosynnema mirum DSM 43827 8330086 YP_003103535.1 CDS Amir_5880 NC_013093.1 6922672 6923343 D PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: psa:PST_2058 probable transcriptional regulator; GntR family transcriptional regulator 6922672..6923343 Actinosynnema mirum DSM 43827 8330087 YP_003103536.1 CDS Amir_5881 NC_013093.1 6923525 6924439 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: rlt:Rleg2_1625 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(6923525..6924439) Actinosynnema mirum DSM 43827 8330088 YP_003103537.1 CDS Amir_5882 NC_013093.1 6924514 6925413 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: pae:PA4779 hypothetical protein; hypothetical protein 6924514..6925413 Actinosynnema mirum DSM 43827 8330089 YP_003103538.1 CDS Amir_5883 NC_013093.1 6925421 6926950 R TIGRFAM: cobyric acid synthase CobQ; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SNO glutamine amidotransferase; cobyrinic acid ac-diamide synthase; KEGG: aeh:Mlg_2812 adenosylcobyric acid synthase (glutamine-hydrolysing); cobyric acid synthase CobQ complement(6925421..6926950) Actinosynnema mirum DSM 43827 8330090 YP_003103539.1 CDS Amir_5884 NC_013093.1 6926997 6927704 D KEGG: bbt:BBta_2719 hypothetical protein; hypothetical protein 6926997..6927704 Actinosynnema mirum DSM 43827 8330091 YP_003103540.1 CDS Amir_5885 NC_013093.1 6927726 6928583 R TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: afw:Anae109_2425 methionine aminopeptidase; methionine aminopeptidase, type I complement(6927726..6928583) Actinosynnema mirum DSM 43827 8330092 YP_003103541.1 CDS Amir_5886 NC_013093.1 6928643 6930442 R PFAM: penicillin-binding protein transpeptidase; NTF2 domain protein transpeptidase; KEGG: mxa:MXAN_7139 penicillin-binding protein; penicillin-binding protein transpeptidase complement(6928643..6930442) Actinosynnema mirum DSM 43827 8330093 YP_003103542.1 CDS Amir_5887 NC_013093.1 6930460 6931314 R PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_1267 hypothetical protein; GCN5-like N-acetyltransferase complement(6930460..6931314) Actinosynnema mirum DSM 43827 8330094 YP_003103543.1 CDS ispG NC_013093.1 6931365 6932522 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(6931365..6932522) Actinosynnema mirum DSM 43827 8330095 YP_003103544.1 CDS Amir_5889 NC_013093.1 6932550 6933761 R PFAM: peptidase M50; KEGG: gbm:Gbem_2749 membrane-associated zinc metalloprotease; peptidase M50 complement(6932550..6933761) Actinosynnema mirum DSM 43827 8330096 YP_003103545.1 CDS Amir_5890 NC_013093.1 6933764 6934984 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(6933764..6934984) Actinosynnema mirum DSM 43827 8330097 YP_003103546.1 CDS Amir_5891 NC_013093.1 6935143 6935409 D PFAM: transglycosylase-associated protein; KEGG: csa:Csal_2587 transglycosylase-associated protein; transglycosylase-associated protein 6935143..6935409 Actinosynnema mirum DSM 43827 8330098 YP_003103547.1 CDS Amir_5892 NC_013093.1 6935607 6936353 R hypothetical protein complement(6935607..6936353) Actinosynnema mirum DSM 43827 8330099 YP_003103548.1 CDS Amir_5893 NC_013093.1 6936367 6937023 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(6936367..6937023) Actinosynnema mirum DSM 43827 8330100 YP_003103549.1 CDS Amir_5894 NC_013093.1 6937027 6938694 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: xcb:XC_0113 two-component system sensor protein; histidine kinase complement(6937027..6938694) Actinosynnema mirum DSM 43827 8330101 YP_003103550.1 CDS Amir_5895 NC_013093.1 6938735 6939562 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: met:M446_6381 ornithine carbamoyltransferase; ornithine carbamoyltransferase complement(6938735..6939562) Actinosynnema mirum DSM 43827 8330102 YP_003103551.1 CDS Amir_5896 NC_013093.1 6939559 6940407 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sus:Acid_2368 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein complement(6939559..6940407) Actinosynnema mirum DSM 43827 8330103 YP_003103552.1 CDS Amir_5897 NC_013093.1 6940407 6941558 R PFAM: extracellular solute-binding protein family 1; KEGG: cak:Caul_3951 extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(6940407..6941558) Actinosynnema mirum DSM 43827 8330104 YP_003103553.1 CDS Amir_5898 NC_013093.1 6941551 6942666 R KEGG: pap:PSPA7_1534 polyamine transport protein PotA; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter; TOBE domain protein; transport-associated OB domain protein; SMART: ATPase AAA; spermidine/putrescine ABC transporter ATPase subunit complement(6941551..6942666) Actinosynnema mirum DSM 43827 8330105 YP_003103554.1 CDS Amir_5899 NC_013093.1 6942913 6943170 D hypothetical protein 6942913..6943170 Actinosynnema mirum DSM 43827 8330106 YP_003103555.1 CDS Amir_5900 NC_013093.1 6943325 6944755 R PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: afw:Anae109_0235 protein kinase; serine/threonine protein kinase complement(6943325..6944755) Actinosynnema mirum DSM 43827 8330107 YP_003103556.1 CDS Amir_5901 NC_013093.1 6944835 6945323 D hypothetical protein 6944835..6945323 Actinosynnema mirum DSM 43827 8330108 YP_003103557.1 CDS Amir_5902 NC_013093.1 6945530 6946636 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(6945530..6946636) Actinosynnema mirum DSM 43827 8330109 YP_003103558.1 CDS Amir_5903 NC_013093.1 6946747 6947697 D PFAM: transcriptional regulator PadR family protein; KEGG: scl:sce3089 PadR family transcriptional regulator; PadR family transcriptional regulator 6946747..6947697 Actinosynnema mirum DSM 43827 8330110 YP_003103559.1 CDS Amir_5904 NC_013093.1 6947769 6948722 R PFAM: aldo/keto reductase; KEGG: rlt:Rleg2_1253 aldo/keto reductase; aldo/keto reductase complement(6947769..6948722) Actinosynnema mirum DSM 43827 8330111 YP_003103560.1 CDS Amir_5905 NC_013093.1 6948757 6949494 R PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: acp:A2cp1_3874 methyltransferase type 11; type 11 methyltransferase complement(6948757..6949494) Actinosynnema mirum DSM 43827 8330112 YP_003103561.1 CDS Amir_5906 NC_013093.1 6949556 6950371 D PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sse:Ssed_0208 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 6949556..6950371 Actinosynnema mirum DSM 43827 8330113 YP_003103562.1 CDS Amir_5907 NC_013093.1 6950442 6951287 R PFAM: phosphatidate cytidylyltransferase; KEGG: mgm:Mmc1_1845 phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase complement(6950442..6951287) Actinosynnema mirum DSM 43827 8330114 YP_003103563.1 CDS Amir_5908 NC_013093.1 6951375 6951932 R TIGRFAM: ribosome recycling factor; PFAM: ribosome recycling factor; KEGG: bha:BH2424 ribosome recycling factor; ribosome recycling factor complement(6951375..6951932) Actinosynnema mirum DSM 43827 8330115 YP_003103564.1 CDS Amir_5909 NC_013093.1 6951978 6952769 R TIGRFAM: uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: gme:Gmet_1252 uridylate kinase; uridylate kinase complement(6951978..6952769) Actinosynnema mirum DSM 43827 8330116 YP_003103565.1 CDS Amir_5910 NC_013093.1 6952852 6953667 R TIGRFAM: translation elongation factor Ts; PFAM: translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; KEGG: bmv:BMASAVP1_A2055 elongation factor Ts; translation elongation factor Ts complement(6952852..6953667) Actinosynnema mirum DSM 43827 8330117 YP_003103566.1 CDS Amir_5911 NC_013093.1 6953749 6954663 R TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: bha:BH2427 30S ribosomal protein S2; 30S ribosomal protein S2 complement(6953749..6954663) Actinosynnema mirum DSM 43827 8330118 YP_003103567.1 CDS Amir_5912 NC_013093.1 6955003 6955998 D PFAM: peptidase M23; KEGG: fibrocystin-L-like protein; peptidase M23 6955003..6955998 Actinosynnema mirum DSM 43827 8330119 YP_003103568.1 CDS Amir_5913 NC_013093.1 6956439 6957257 R KEGG: mgm:Mmc1_3037 RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 3 domain protein; sigma- 70 region 4 domain protein; RNA polymerase sigma-28 subunit FliA/WhiG complement(6956439..6957257) Actinosynnema mirum DSM 43827 8330120 YP_003103569.1 CDS Amir_5914 NC_013093.1 6958093 6959070 R PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: afw:Anae109_2689 tyrosine recombinase XerC; integrase family protein complement(6958093..6959070) Actinosynnema mirum DSM 43827 8330121 YP_003103570.1 CDS Amir_5916 NC_013093.1 6960896 6962416 R KEGG: ank:AnaeK_3688 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; Mg chelatase, subunit ChlI complement(6960896..6962416) Actinosynnema mirum DSM 43827 8330123 YP_003103571.1 CDS Amir_5917 NC_013093.1 6962416 6962769 R PFAM: protein of unknown function UPF0102; KEGG: dps:DP2807 hypothetical protein; hypothetical protein complement(6962416..6962769) Actinosynnema mirum DSM 43827 8330124 YP_003103572.1 CDS Amir_5918 NC_013093.1 6963062 6963385 R hypothetical protein complement(6963062..6963385) Actinosynnema mirum DSM 43827 8330125 YP_003103573.1 CDS Amir_5919 NC_013093.1 6963405 6964181 R PFAM: ribonuclease HII/HIII; KEGG: ribonuclease H; ribonuclease H complement(6963405..6964181) Actinosynnema mirum DSM 43827 8330126 YP_003103574.1 CDS Amir_5920 NC_013093.1 6964191 6965090 R TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: TPP1; chloroplast thylakoid processing peptidase; K03100 signal peptidase I; signal peptidase I complement(6964191..6965090) Actinosynnema mirum DSM 43827 8330127 YP_003103575.1 CDS Amir_5921 NC_013093.1 6965095 6965961 R KEGG: signal peptidase, ; K03100 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; signal peptidase I complement(6965095..6965961) Actinosynnema mirum DSM 43827 8330128 YP_003103576.1 CDS Amir_5922 NC_013093.1 6966071 6966430 R TIGRFAM: ribosomal protein L19; PFAM: ribosomal protein L19; KEGG: bha:BH2478 50S ribosomal protein L19; 50S ribosomal protein L19 complement(6966071..6966430) Actinosynnema mirum DSM 43827 8330129 YP_003103577.1 CDS Amir_5923 NC_013093.1 6966602 6967342 R KEGG: glo:Glov_2453 tRNA (guanine-N1)- methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; tRNA (guanine-N1)-methyltransferase complement(6966602..6967342) Actinosynnema mirum DSM 43827 8330130 YP_003103578.1 CDS Amir_5924 NC_013093.1 6967332 6967850 R TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; KEGG: dds:Ddes_1801 16S rRNA processing protein RimM; 16S rRNA processing protein RimM complement(6967332..6967850) Actinosynnema mirum DSM 43827 8330131 YP_003103579.1 CDS Amir_5925 NC_013093.1 6967857 6968096 R KEGG: bha:BH2482 hypothetical protein; hypothetical protein complement(6967857..6968096) Actinosynnema mirum DSM 43827 8330132 YP_003103580.1 CDS Amir_5926 NC_013093.1 6968093 6968530 R TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; KEGG: swi:Swit_2657 30S ribosomal protein S16; 30S ribosomal protein S16 complement(6968093..6968530) Actinosynnema mirum DSM 43827 8330133 YP_003103581.1 CDS Amir_5927 NC_013093.1 6968684 6969442 R PFAM: LamB/YcsF family protein; KEGG: pst:PSPTO_5378 hypothetical protein; LamB/YcsF family protein complement(6968684..6969442) Actinosynnema mirum DSM 43827 8330134 YP_003103582.1 CDS Amir_5928 NC_013093.1 6969439 6970155 R PFAM: abortive infection protein; KEGG: pcr:Pcryo_0794 abortive infection protein; abortive infection protein complement(6969439..6970155) Actinosynnema mirum DSM 43827 8330135 YP_003103583.1 CDS Amir_5929 NC_013093.1 6970955 6972025 R PFAM: amidohydrolase; Amidohydrolase 3; KEGG: pzu:PHZ_c3063 Xaa-Pro dipeptidase; amidohydrolase complement(6970955..6972025) Actinosynnema mirum DSM 43827 8330136 YP_003103584.1 CDS Amir_5930 NC_013093.1 6972022 6973578 R KEGG: dds:Ddes_1804 signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; signal recognition particle protein complement(6972022..6973578) Actinosynnema mirum DSM 43827 8330137 YP_003103585.1 CDS Amir_5931 NC_013093.1 6973895 6974443 R KEGG: mlo:mll6593 hypothetical protein; hypothetical protein complement(6973895..6974443) Actinosynnema mirum DSM 43827 8330138 YP_003103586.1 CDS Amir_5932 NC_013093.1 6974903 6977266 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK; PII uridylyl-transferase complement(6974903..6977266) Actinosynnema mirum DSM 43827 8330139 YP_003103587.1 CDS Amir_5933 NC_013093.1 6977287 6977625 R PFAM: nitrogen regulatory protein P-II; KEGG: cja:CJA_3390 nitrogen regulatory protein P-II; nitrogen regulatory protein P-II complement(6977287..6977625) Actinosynnema mirum DSM 43827 8330140 YP_003103588.1 CDS Amir_5934 NC_013093.1 6977622 6978965 R TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: pca:Pcar_2589 ammonium transporter; ammonium transporter complement(6977622..6978965) Actinosynnema mirum DSM 43827 8330141 YP_003103589.1 CDS Amir_5935 NC_013093.1 6979450 6981006 R PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: hypothetical protein; TAP domain-containing protein complement(6979450..6981006) Actinosynnema mirum DSM 43827 8330142 YP_003103590.1 CDS Amir_5936 NC_013093.1 6981139 6982134 R catalyzes the formation of S-ureidoglycolate and urea from allantoate; allantoicase complement(6981139..6982134) Actinosynnema mirum DSM 43827 8330143 YP_003103591.1 CDS Amir_5937 NC_013093.1 6982131 6983840 R KEGG: scl:sce5876 allantoinase; TIGRFAM: allantoinase; PFAM: amidohydrolase; Amidohydrolase 3; allantoinase complement(6982131..6983840) Actinosynnema mirum DSM 43827 8330144 YP_003103592.1 CDS Amir_5938 NC_013093.1 6984153 6984647 D TIGRFAM: OHCU decarboxylase; KEGG: spe:Spro_0938 urate oxidase, N- terminal; OHCU decarboxylase 6984153..6984647 Actinosynnema mirum DSM 43827 8330145 YP_003103593.1 CDS Amir_5939 NC_013093.1 6984682 6985563 D KEGG: scl:sce4023 uricase; TIGRFAM: urate oxidase; PFAM: Uricase; urate oxidase 6984682..6985563 Actinosynnema mirum DSM 43827 8330146 YP_003103594.1 CDS Amir_5940 NC_013093.1 6985594 6986049 R hypothetical protein complement(6985594..6986049) Actinosynnema mirum DSM 43827 8330147 YP_003103595.1 CDS Amir_5941 NC_013093.1 6986140 6987345 R KEGG: scl:sce5882 hypothetical protein; hypothetical protein complement(6986140..6987345) Actinosynnema mirum DSM 43827 8330148 YP_003103596.1 CDS Amir_5942 NC_013093.1 6987347 6988888 R KEGG: mxa:MXAN_6441 malate synthase; TIGRFAM: malate synthase A; PFAM: malate synthase; malate synthase A complement(6987347..6988888) Actinosynnema mirum DSM 43827 8330149 YP_003103597.1 CDS Amir_5943 NC_013093.1 6988978 6989751 D PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: bid:Bind_3440 IclR family transcriptional regulator; IclR family transcriptional regulator 6988978..6989751 Actinosynnema mirum DSM 43827 8330150 YP_003103598.1 CDS Amir_5944 NC_013093.1 6989795 6990187 D hypothetical protein 6989795..6990187 Actinosynnema mirum DSM 43827 8330151 YP_003103599.1 CDS Amir_5945 NC_013093.1 6990300 6991772 R KEGG: pmy:Pmen_4175 signal recognition particle- docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; signal recognition particle-docking protein FtsY complement(6990300..6991772) Actinosynnema mirum DSM 43827 8330152 YP_003103600.1 CDS anmK NC_013093.1 6991893 6993017 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 6991893..6993017 Actinosynnema mirum DSM 43827 8330153 YP_003103601.1 CDS Amir_5947 NC_013093.1 6993004 6994533 D PFAM: Na+/solute symporter; KEGG: gdi:GDI1156 sodium cotransporter; Na+/solute symporter 6993004..6994533 Actinosynnema mirum DSM 43827 8330154 YP_003103602.1 CDS Amir_5948 NC_013093.1 6994874 6995812 R PFAM: GCN5-related N-acetyltransferase; KEGG: pzu:PHZ_c1335 L-2,4-diaminobutyric acid acetyltransferase; GCN5-like N-acetyltransferase complement(6994874..6995812) Actinosynnema mirum DSM 43827 8330155 YP_003103603.1 CDS Amir_5949 NC_013093.1 6995854 6996486 D hypothetical protein 6995854..6996486 Actinosynnema mirum DSM 43827 8330156 YP_003103604.1 CDS Amir_5950 NC_013093.1 6996509 6996859 D hypothetical protein 6996509..6996859 Actinosynnema mirum DSM 43827 8330157 YP_003103605.1 CDS Amir_5951 NC_013093.1 6996950 6997684 D PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: gur:Gura_4298 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 6996950..6997684 Actinosynnema mirum DSM 43827 8330158 YP_003103606.1 CDS Amir_5952 NC_013093.1 6997724 7001308 R TIGRFAM: chromosome segregation protein SMC; PFAM: hypothetical protein; SMCs flexible hinge domain protein; KEGG: bha:BH2487 chromosome segregation SMC protein; chromosome segregation protein SMC complement(6997724..7001308) Actinosynnema mirum DSM 43827 8330159 YP_003103607.1 CDS Amir_5953 NC_013093.1 7001349 7002161 R KEGG: bps:BPSL1109 hypothetical protein; transmembrane anti-sigma factor complement(7001349..7002161) Actinosynnema mirum DSM 43827 8330160 YP_003103608.1 CDS Amir_5954 NC_013093.1 7002161 7002649 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: rpb:RPB_3549 RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit complement(7002161..7002649) Actinosynnema mirum DSM 43827 8330161 YP_003103609.1 CDS Amir_5955 NC_013093.1 7002683 7002970 R PFAM: acylphosphatase; KEGG: met:M446_0372 acylphosphatase; acylphosphatase complement(7002683..7002970) Actinosynnema mirum DSM 43827 8330162 YP_003103610.1 CDS Amir_5956 NC_013093.1 7002996 7003676 D PFAM: SCP-like extracellular; KEGG: bcy:Bcer98_1016 hypothetical protein; SCP-like extracellular 7002996..7003676 Actinosynnema mirum DSM 43827 8330163 YP_003103611.1 CDS Amir_5957 NC_013093.1 7003708 7004235 R hypothetical protein complement(7003708..7004235) Actinosynnema mirum DSM 43827 8330164 YP_003103612.1 CDS Amir_5958 NC_013093.1 7004406 7004897 D KEGG: hypothetical protein LOC763622; hypothetical protein 7004406..7004897 Actinosynnema mirum DSM 43827 8330165 YP_003103613.1 CDS Amir_5959 NC_013093.1 7005414 7006535 D PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bja:blr2205 dehydrogenase; FAD dependent oxidoreductase 7005414..7006535 Actinosynnema mirum DSM 43827 8330166 YP_003103614.1 CDS Amir_5960 NC_013093.1 7006648 7007328 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: set:SEN0666 KDP operon transcriptional regulatory protein; winged helix family two component transcriptional regulator complement(7006648..7007328) Actinosynnema mirum DSM 43827 8330167 YP_003103615.1 CDS Amir_5961 NC_013093.1 7007648 7008076 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bmj:BMULJ_04432 MarR family transcriptional regulator; MarR family transcriptional regulator 7007648..7008076 Actinosynnema mirum DSM 43827 8330168 YP_003103616.1 CDS Amir_5962 NC_013093.1 7008410 7009285 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(7008410..7009285) Actinosynnema mirum DSM 43827 8330169 YP_003103617.1 CDS Amir_5963 NC_013093.1 7009295 7009546 R hypothetical protein complement(7009295..7009546) Actinosynnema mirum DSM 43827 8330170 YP_003103618.1 CDS Amir_5964 NC_013093.1 7009554 7010357 R KEGG: sat:SYN_00796 ribonuclease III; TIGRFAM: ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; SMART: ribonuclease III; double-stranded RNA binding domain protein; ribonuclease III complement(7009554..7010357) Actinosynnema mirum DSM 43827 8330171 YP_003103619.1 CDS rpmF NC_013093.1 7010385 7010567 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(7010385..7010567) Actinosynnema mirum DSM 43827 8330172 YP_003103620.1 CDS Amir_5966 NC_013093.1 7010570 7011016 R PFAM: protein of unknown function DUF177; KEGG: afw:Anae109_2742 hypothetical protein; hypothetical protein complement(7010570..7011016) Actinosynnema mirum DSM 43827 8330173 YP_003103621.1 CDS Amir_5967 NC_013093.1 7011277 7011993 R KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; cell division initiation protein complement(7011277..7011993) Actinosynnema mirum DSM 43827 8330174 YP_003103622.1 CDS Amir_5968 NC_013093.1 7012129 7012611 R KEGG: bha:BH2589 lipopolysaccharide core biosynthesis; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; pantetheine-phosphate adenylyltransferase complement(7012129..7012611) Actinosynnema mirum DSM 43827 8330175 YP_003103623.1 CDS Amir_5969 NC_013093.1 7012664 7013230 R TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase KEGG: scl:sce8059 methylase; methyltransferase complement(7012664..7013230) Actinosynnema mirum DSM 43827 8330176 YP_003103624.1 CDS Amir_5970 NC_013093.1 7013306 7014388 R KEGG: mxa:MXAN_6257 hypothetical protein; hypothetical protein complement(7013306..7014388) Actinosynnema mirum DSM 43827 8330177 YP_003103625.1 CDS Amir_5971 NC_013093.1 7014450 7014893 R hypothetical protein complement(7014450..7014893) Actinosynnema mirum DSM 43827 8330178 YP_003103626.1 CDS Amir_5972 NC_013093.1 7014878 7015225 R hypothetical protein complement(7014878..7015225) Actinosynnema mirum DSM 43827 8330179 YP_003103627.1 CDS Amir_5973 NC_013093.1 7015428 7018805 R biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase complement(7015428..7018805) Actinosynnema mirum DSM 43827 8330180 YP_003103628.1 CDS Amir_5974 NC_013093.1 7019075 7020478 D KEGG: hypothetical protein; hypothetical protein 7019075..7020478 Actinosynnema mirum DSM 43827 8330181 YP_003103629.1 CDS Amir_5975 NC_013093.1 7020612 7021439 R hypothetical protein complement(7020612..7021439) Actinosynnema mirum DSM 43827 8330182 YP_003103630.1 CDS Amir_5977 NC_013093.1 7022476 7024677 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(7022476..7024677) Actinosynnema mirum DSM 43827 8330184 YP_003103631.1 CDS Amir_5978 NC_013093.1 7024732 7026369 R PFAM: Dak phosphatase; KEGG: bsu:BSU15840 hypothetical protein; Dak phosphatase complement(7024732..7026369) Actinosynnema mirum DSM 43827 8330185 YP_003103632.1 CDS Amir_5979 NC_013093.1 7026517 7026708 D TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: aba:Acid345_0165 LSU ribosomal protein L28P; 50S ribosomal protein L28 7026517..7026708 Actinosynnema mirum DSM 43827 8330186 YP_003103633.1 CDS Amir_5980 NC_013093.1 7026929 7027807 R PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4- dehydrorhamnose reductase; KEGG: ade:Adeh_4303 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(7026929..7027807) Actinosynnema mirum DSM 43827 8330187 YP_003103634.1 CDS Amir_5981 NC_013093.1 7027887 7028381 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: acp:A2cp1_4259 transcriptional regulator, MarR family; MarR family transcriptional regulator 7027887..7028381 Actinosynnema mirum DSM 43827 8330188 YP_003103635.1 CDS Amir_5982 NC_013093.1 7028478 7029152 R PFAM: uracil-DNA glycosylase; KEGG: mxa:MXAN_0760 uracil-DNA glycosylase; uracil-DNA glycosylase complement(7028478..7029152) Actinosynnema mirum DSM 43827 8330189 YP_003103636.1 CDS Amir_5983 NC_013093.1 7029167 7029685 R KEGG: sil:SPO1946 transferase family protein; transferase family protein complement(7029167..7029685) Actinosynnema mirum DSM 43827 8330190 YP_003103637.1 CDS Amir_5984 NC_013093.1 7029708 7030223 R PFAM: GCN5-related N-acetyltransferase; KEGG: hypothetical protein; GCN5-like N-acetyltransferase complement(7029708..7030223) Actinosynnema mirum DSM 43827 8330191 YP_003103638.1 CDS Amir_5985 NC_013093.1 7030249 7031214 R KEGG: gur:Gura_0692 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; thiamine-monophosphate kinase complement(7030249..7031214) Actinosynnema mirum DSM 43827 8330192 YP_003103639.1 CDS Amir_5986 NC_013093.1 7031312 7031545 D PFAM: regulatory protein AsnC/Lrp family; KEGG: pzu:PHZ_c3044 transcriptional regulator, Lrp/AsnC family; AsnC family transcriptional regulator 7031312..7031545 Actinosynnema mirum DSM 43827 8330193 YP_003103640.1 CDS Amir_5987 NC_013093.1 7031614 7032156 D hypothetical protein 7031614..7032156 Actinosynnema mirum DSM 43827 8330194 YP_003103641.1 CDS ddl NC_013093.1 7032227 7033294 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(7032227..7033294) Actinosynnema mirum DSM 43827 8330195 YP_003103642.1 CDS Amir_5989 NC_013093.1 7033891 7034358 D PFAM: cysteine dioxygenase type I; cupin; KEGG: mxa:MXAN_0927 cysteine dioxygenase, type I; cysteine dioxygenase type I 7033891..7034358 Actinosynnema mirum DSM 43827 8330196 YP_003103643.1 CDS Amir_5990 NC_013093.1 7034433 7035080 R KEGG: aba:Acid345_2785 hypothetical protein; hypothetical protein complement(7034433..7035080) Actinosynnema mirum DSM 43827 8330197 YP_003103644.1 CDS Amir_5991 NC_013093.1 7035149 7036519 D PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: ade:Adeh_2233 GntR family transcriptional regulator; GntR family transcriptional regulator 7035149..7036519 Actinosynnema mirum DSM 43827 8330198 YP_003103645.1 CDS Amir_5992 NC_013093.1 7036769 7037167 D hypothetical protein 7036769..7037167 Actinosynnema mirum DSM 43827 8330199 YP_003103646.1 CDS Amir_5993 NC_013093.1 7037214 7037408 R PFAM: protein of unknown function DUF397; hypothetical protein complement(7037214..7037408) Actinosynnema mirum DSM 43827 8330200 YP_003103647.1 CDS Amir_5994 NC_013093.1 7037398 7038243 R hypothetical protein complement(7037398..7038243) Actinosynnema mirum DSM 43827 8330201 YP_003103648.1 CDS Amir_5995 NC_013093.1 7038481 7038954 D KEGG: azc:AZC_3655 hypothetical protein; hypothetical protein 7038481..7038954 Actinosynnema mirum DSM 43827 8330202 YP_003103649.1 CDS Amir_5996 NC_013093.1 7038951 7039358 D hypothetical protein 7038951..7039358 Actinosynnema mirum DSM 43827 8330203 YP_003103650.1 CDS Amir_5997 NC_013093.1 7039404 7040531 R catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; cystathionine gamma-lyase complement(7039404..7040531) Actinosynnema mirum DSM 43827 8330204 YP_003103651.1 CDS Amir_5998 NC_013093.1 7040531 7041532 R PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; ketopantoate reductase ApbA/PanE domain protein; NADP oxidoreductase coenzyme F420-dependent; KEGG: ade:Adeh_0396 glycerol-3-phosphate dehydrogenase (NAD(P)+); glycerol-3-phosphate dehydrogenase (NAD(P)(+)) complement(7040531..7041532) Actinosynnema mirum DSM 43827 8330205 YP_003103652.1 CDS Amir_5999 NC_013093.1 7041534 7042235 R PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: ank:AnaeK_4035 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase complement(7041534..7042235) Actinosynnema mirum DSM 43827 8330206 YP_003103653.1 CDS Amir_6000 NC_013093.1 7042317 7042931 D KEGG: pzu:PHZ_c2537 hypothetical protein; hypothetical protein 7042317..7042931 Actinosynnema mirum DSM 43827 8330207 YP_003103654.1 CDS Amir_6001 NC_013093.1 7042904 7043218 D KEGG: hypothetical protein; hypothetical protein 7042904..7043218 Actinosynnema mirum DSM 43827 8330208 YP_003103655.1 CDS Amir_6002 NC_013093.1 7043440 7045578 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 7043440..7045578 Actinosynnema mirum DSM 43827 8330209 YP_003103656.1 CDS Amir_6003 NC_013093.1 7045582 7046526 D PFAM: NUDIX hydrolase; phosphoglycerate mutase; KEGG: bja:bll6630 hypothetical protein; NUDIX hydrolase 7045582..7046526 Actinosynnema mirum DSM 43827 8330210 YP_003103657.1 CDS Amir_6004 NC_013093.1 7048316 7049173 R PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; KEGG: hypothetical protein LOC679057; histone family protein DNA-binding protein complement(7048316..7049173) Actinosynnema mirum DSM 43827 8330211 YP_003103658.1 CDS Amir_6005 NC_013093.1 7049381 7049983 R KEGG: aba:Acid345_2915 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; 3-isopropylmalate dehydratase, small subunit complement(7049381..7049983) Actinosynnema mirum DSM 43827 8330212 YP_003103659.1 CDS Amir_6006 NC_013093.1 7049998 7051416 R KEGG: aba:Acid345_2916 isopropylmalate isomerase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein; 3-isopropylmalate dehydratase, large subunit complement(7049998..7051416) Actinosynnema mirum DSM 43827 8330213 YP_003103660.1 CDS Amir_6007 NC_013093.1 7051495 7052196 D PFAM: transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: cti:RALTA_B1947 transcriptional regulator, IclR family; IclR family transcriptional regulator 7051495..7052196 Actinosynnema mirum DSM 43827 8330214 YP_003103661.1 CDS Amir_6008 NC_013093.1 7053052 7053735 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bha:BH0473 hypothetical protein; HAD superfamily hydrolase complement(7053052..7053735) Actinosynnema mirum DSM 43827 8330218 YP_003103662.1 CDS gltX NC_013093.1 7053894 7055384 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(7053894..7055384) Actinosynnema mirum DSM 43827 8330219 YP_003103663.1 CDS Amir_6010 NC_013093.1 7055473 7056705 D PFAM: monooxygenase FAD-binding; KEGG: mrd:Mrad2831_2174 monooxygenase FAD-binding; FAD-binding monooxygenase 7055473..7056705 Actinosynnema mirum DSM 43827 8330220 YP_003103664.1 CDS Amir_6011 NC_013093.1 7056931 7057701 R PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: scl:sce2870 fumarylacetoacetase; 5-oxopent-3-ene-1,2, 5-tricarboxylatedecarboxylase complement(7056931..7057701) Actinosynnema mirum DSM 43827 8330221 YP_003103665.1 CDS Amir_6012 NC_013093.1 7057758 7058411 D KEGG: hypothetical protein; hypothetical protein 7057758..7058411 Actinosynnema mirum DSM 43827 8330222 YP_003103666.1 CDS Amir_6013 NC_013093.1 7058458 7060071 R TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: scl:sce3734 alpha- isopropylmalate/homocitrate synthase family transferase; alpha-isopropylmalate/homocitrate synthase family transferase complement(7058458..7060071) Actinosynnema mirum DSM 43827 8330223 YP_003103667.1 CDS Amir_6014 NC_013093.1 7060690 7061727 R PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase complement(7060690..7061727) Actinosynnema mirum DSM 43827 8330224 YP_003103668.1 CDS Amir_6015 NC_013093.1 7062011 7065289 R PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: glo:Glov_1721 peptidase S8 and S53 subtilisin kexin sedolisin; peptidase S8/S53 subtilisin kexin sedolisin complement(7062011..7065289) Actinosynnema mirum DSM 43827 8330225 YP_003103669.1 CDS Amir_6016 NC_013093.1 7065514 7065639 D hypothetical protein 7065514..7065639 Actinosynnema mirum DSM 43827 8330226 YP_003103670.1 CDS Amir_6017 NC_013093.1 7065728 7067326 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(7065728..7067326) Actinosynnema mirum DSM 43827 8330227 YP_003103671.1 CDS Amir_6018 NC_013093.1 7067834 7068103 R PFAM: protein of unknown function DUF397; hypothetical protein complement(7067834..7068103) Actinosynnema mirum DSM 43827 8330228 YP_003103672.1 CDS Amir_6019 NC_013093.1 7068216 7069229 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(7068216..7069229) Actinosynnema mirum DSM 43827 8330229 YP_003103673.1 CDS ilvH NC_013093.1 7069289 7069795 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(7069289..7069795) Actinosynnema mirum DSM 43827 8330230 YP_003103674.1 CDS Amir_6021 NC_013093.1 7069844 7071679 R acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit complement(7069844..7071679) Actinosynnema mirum DSM 43827 8330231 YP_003103675.1 CDS Amir_6022 NC_013093.1 7071914 7072594 D KEGG: mucin-associated surface protein (MASP); hypothetical protein 7071914..7072594 Actinosynnema mirum DSM 43827 8330232 YP_003103676.1 CDS Amir_6023 NC_013093.1 7072730 7073149 D PFAM: vitamin K epoxide reductase; SMART: vitamin K epoxide reductase; KEGG: hypothetical protein; vitamin K epoxide reductase 7072730..7073149 Actinosynnema mirum DSM 43827 8330233 YP_003103677.1 CDS Amir_6024 NC_013093.1 7073265 7075109 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 7073265..7075109 Actinosynnema mirum DSM 43827 8330234 YP_003103678.1 CDS Amir_6025 NC_013093.1 7075280 7076131 R PFAM: DoxX family protein; KEGG: slo:Shew_2277 DoxX family protein; DoxX family protein complement(7075280..7076131) Actinosynnema mirum DSM 43827 8330235 YP_003103679.1 CDS Amir_6026 NC_013093.1 7076321 7077031 R KEGG: hypothetical protein; hypothetical protein complement(7076321..7077031) Actinosynnema mirum DSM 43827 8330236 YP_003103680.1 CDS Amir_6027 NC_013093.1 7077291 7078169 R PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: hypothetical protein; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase complement(7077291..7078169) Actinosynnema mirum DSM 43827 8330237 YP_003103681.1 CDS Amir_6028 NC_013093.1 7078195 7079148 D PFAM: alpha/beta hydrolase fold; KEGG: afw:Anae109_2061 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 7078195..7079148 Actinosynnema mirum DSM 43827 8330238 YP_003103682.1 CDS Amir_6029 NC_013093.1 7079181 7080338 D KEGG: bha:BH2090 glucose dehydrogenase-B; glucose/sorbosone dehydrogenase-like protein 7079181..7080338 Actinosynnema mirum DSM 43827 8330239 YP_003103683.1 CDS Amir_6030 NC_013093.1 7080370 7083012 R PFAM: hypothetical protein; hypothetical protein; SMART: hypothetical protein; KEGG: sus:Acid_3454 tetratricopeptide TPR_4; hypothetical protein complement(7080370..7083012) Actinosynnema mirum DSM 43827 8330240 YP_003103684.1 CDS Amir_6031 NC_013093.1 7083104 7083466 R KEGG: clx-1; COllagen sequence X-hybridizing; hypothetical protein complement(7083104..7083466) Actinosynnema mirum DSM 43827 8330241 YP_003103685.1 CDS gatB NC_013093.1 7083949 7085454 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(7083949..7085454) Actinosynnema mirum DSM 43827 8330242 YP_003103686.1 CDS Amir_6033 NC_013093.1 7085451 7085642 R hypothetical protein complement(7085451..7085642) Actinosynnema mirum DSM 43827 8330243 YP_003103687.1 CDS gatA NC_013093.1 7085639 7087159 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(7085639..7087159) Actinosynnema mirum DSM 43827 8330244 YP_003103688.1 CDS Amir_6035 NC_013093.1 7087156 7087455 R TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; KEGG: gsu:GSU3383 glutamyl-tRNA(Gln) amidotransferase, C subunit; glutamyl-tRNA(Gln) amidotransferase subunit C complement(7087156..7087455) Actinosynnema mirum DSM 43827 8330245 YP_003103689.1 CDS Amir_6036 NC_013093.1 7087720 7088367 D PFAM: amino acid-binding ACT domain protein; KEGG: bsu:BSU23550 malolactic enzyme; amino acid-binding ACT domain-containing protein 7087720..7088367 Actinosynnema mirum DSM 43827 8330246 YP_003103690.1 CDS Amir_6037 NC_013093.1 7088486 7088974 D PFAM: hypothetical protein; KEGG: mgm:Mmc1_2013 zinc finger, SWIM domain protein; hypothetical protein 7088486..7088974 Actinosynnema mirum DSM 43827 8330247 YP_003103691.1 CDS Amir_6038 NC_013093.1 7089303 7091753 R KEGG: mca:MCA2438 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4- type; NAD-dependent DNA ligase OB-fold; SMART: NAD-dependent DNA ligase; BRCT domain protein; DNA ligase, NAD-dependent complement(7089303..7091753) Actinosynnema mirum DSM 43827 8330248 YP_003103692.1 CDS Amir_6039 NC_013093.1 7091834 7092481 R hypothetical protein complement(7091834..7092481) Actinosynnema mirum DSM 43827 8330249 YP_003103693.1 CDS Amir_6040 NC_013093.1 7092494 7093381 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: acr:Acry_2159 LysR family transcriptional regulator; LysR family transcriptional regulator complement(7092494..7093381) Actinosynnema mirum DSM 43827 8330250 YP_003103694.1 CDS Amir_6041 NC_013093.1 7093393 7094259 D PFAM: conserved hypothetical protein; KEGG: xau:Xaut_2089 hypothetical protein; hypothetical protein 7093393..7094259 Actinosynnema mirum DSM 43827 8330251 YP_003103695.1 CDS Amir_6042 NC_013093.1 7094308 7095315 R PFAM: methionine synthase vitamin-B12 independent; KEGG: dal:Dalk_5194 hypothetical protein; methionine synthase vitamin-B12 independent complement(7094308..7095315) Actinosynnema mirum DSM 43827 8330252 YP_003103696.1 CDS Amir_6043 NC_013093.1 7095423 7095752 R hypothetical protein complement(7095423..7095752) Actinosynnema mirum DSM 43827 8330253 YP_003103697.1 CDS Amir_6044 NC_013093.1 7095850 7096368 D KEGG: bcb:BCB4264_A1184 hypothetical protein; hypothetical protein 7095850..7096368 Actinosynnema mirum DSM 43827 8330254 YP_003103698.1 CDS mnmA NC_013093.1 7096401 7097489 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(7096401..7097489) Actinosynnema mirum DSM 43827 8330255 YP_003103699.1 CDS Amir_6046 NC_013093.1 7097495 7098670 R PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cysteine desulfurase NifS; K04487 cysteine desulfurase; class V aminotransferase complement(7097495..7098670) Actinosynnema mirum DSM 43827 8330256 YP_003103700.1 CDS Amir_6047 NC_013093.1 7098670 7100217 R PFAM: major facilitator superfamily MFS_1; KEGG: dac:Daci_3895 major facilitator transporter; major facilitator superfamily protein complement(7098670..7100217) Actinosynnema mirum DSM 43827 8330257 YP_003103701.1 CDS Amir_6048 NC_013093.1 7100348 7101340 R PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: cti:RALTA_A2392 phospholipid/glycerol acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase transmembrane protein; phospholipid/glycerol acyltransferase complement(7100348..7101340) Actinosynnema mirum DSM 43827 8330258 YP_003103702.1 CDS Amir_6049 NC_013093.1 7101340 7102110 R KEGG: eba:ebA5570 hypothetical protein; ornithine-acyl(acyl carrier protein) N- acyltransferase complement(7101340..7102110) Actinosynnema mirum DSM 43827 8330259 YP_003103703.1 CDS Amir_6050 NC_013093.1 7102334 7103293 R PFAM: electron transfer flavoprotein alpha subunit; electron transfer flavoprotein alpha/beta-subunit; KEGG: met:M446_2006 electron transfer flavoprotein alpha subunit; electron transfer flavoprotein alpha subunit complement(7102334..7103293) Actinosynnema mirum DSM 43827 8330260 YP_003103704.1 CDS Amir_6051 NC_013093.1 7103314 7104093 R PFAM: electron transfer flavoprotein alpha/beta- subunit; KEGG: sat:SYN_02636 electron transfer flavoprotein beta-subunit; electron transfer flavoprotein alpha/beta- subunit complement(7103314..7104093) Actinosynnema mirum DSM 43827 8330261 YP_003103705.1 CDS Amir_6052 NC_013093.1 7104349 7105191 D TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: bsu:BSU11110 hypothetical protein; degV family protein 7104349..7105191 Actinosynnema mirum DSM 43827 8330262 YP_003103706.1 CDS Amir_6053 NC_013093.1 7105268 7105411 D hypothetical protein 7105268..7105411 Actinosynnema mirum DSM 43827 8330263 YP_003103707.1 CDS Amir_6054 NC_013093.1 7105585 7107504 R KEGG: hypothetical protein; hypothetical protein complement(7105585..7107504) Actinosynnema mirum DSM 43827 8330264 YP_003103708.1 CDS Amir_6055 NC_013093.1 7107522 7108244 R KEGG: Eln; elastin; hypothetical protein complement(7107522..7108244) Actinosynnema mirum DSM 43827 8330265 YP_003103709.1 CDS Amir_6056 NC_013093.1 7108632 7109378 D PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: sus:Acid_7436 methyltransferase type 11; type 11 methyltransferase 7108632..7109378 Actinosynnema mirum DSM 43827 8330266 YP_003103710.1 CDS Amir_6057 NC_013093.1 7109375 7110874 D PFAM: glycoside hydrolase family 57; KEGG: scl:sce1626 hypothetical protein; glycoside hydrolase family protein 7109375..7110874 Actinosynnema mirum DSM 43827 8330267 YP_003103711.1 CDS Amir_6058 NC_013093.1 7111116 7112369 D PFAM: glycosyl transferase group 1; KEGG: bha:BH1415 hypothetical protein; group 1 glycosyl transferase 7111116..7112369 Actinosynnema mirum DSM 43827 8330268 YP_003103712.1 CDS Amir_6059 NC_013093.1 7112403 7112684 R hypothetical protein complement(7112403..7112684) Actinosynnema mirum DSM 43827 8330269 YP_003103713.1 CDS Amir_6060 NC_013093.1 7112929 7113357 R KEGG: afw:Anae109_4021 dual specificity protein phosphatase; hypothetical protein complement(7112929..7113357) Actinosynnema mirum DSM 43827 8330270 YP_003103714.1 CDS Amir_6061 NC_013093.1 7113391 7114137 R KEGG: bpy:Bphyt_6269 acetyltransferase; acetyltransferase (isoleucine patch superfamily)-like protein complement(7113391..7114137) Actinosynnema mirum DSM 43827 8330271 YP_003103715.1 CDS Amir_6062 NC_013093.1 7114207 7115139 D PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: asa:ASA_2899 ribonucleoside hydrolase 1; Inosine/uridine-preferring nucleoside hydrolase 7114207..7115139 Actinosynnema mirum DSM 43827 8330272 YP_003103716.1 CDS Amir_6063 NC_013093.1 7115183 7116334 R hypothetical protein complement(7115183..7116334) Actinosynnema mirum DSM 43827 8330273 YP_003103717.1 CDS Amir_6064 NC_013093.1 7116337 7117332 R PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: bja:bll7234 hypothetical protein; type 11 methyltransferase complement(7116337..7117332) Actinosynnema mirum DSM 43827 8330274 YP_003103718.1 CDS Amir_6065 NC_013093.1 7117322 7118101 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: dal:Dalk_2640 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase complement(7117322..7118101) Actinosynnema mirum DSM 43827 8330275 YP_003103719.1 CDS Amir_6066 NC_013093.1 7118222 7119043 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sfu:Sfum_3281 ABC transporter; ABC transporter complement(7118222..7119043) Actinosynnema mirum DSM 43827 8330276 YP_003103720.1 CDS Amir_6067 NC_013093.1 7119238 7121343 D KEGG: ade:Adeh_1056 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; glycogen debranching protein GlgX 7119238..7121343 Actinosynnema mirum DSM 43827 8330277 YP_003103721.1 CDS Amir_6068 NC_013093.1 7121730 7122353 D PFAM: cysteine dioxygenase type I; KEGG: mxa:MXAN_0927 cysteine dioxygenase, type I; cysteine dioxygenase type I 7121730..7122353 Actinosynnema mirum DSM 43827 8330278 YP_003103722.1 CDS Amir_6069 NC_013093.1 7122350 7122964 D SMART: rhodanese domain protein; KEGG: hypothetical protein; rhodanese domain-containing protein 7122350..7122964 Actinosynnema mirum DSM 43827 8330279 YP_003103723.1 CDS Amir_6070 NC_013093.1 7123257 7124369 D PFAM: hypothetical protein; KEGG: pin:Ping_0445 colicin uptake-like protein; hypothetical protein 7123257..7124369 Actinosynnema mirum DSM 43827 8330280 YP_003103724.1 CDS Amir_6071 NC_013093.1 7124495 7127002 R KEGG: gsu:GSU0371 carbohydrate phosphorylase family protein; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; alpha-glucan phosphorylase complement(7124495..7127002) Actinosynnema mirum DSM 43827 8330281 YP_003103725.1 CDS Amir_6072 NC_013093.1 7127911 7129890 D PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: afw:Anae109_3071 alpha amylase catalytic region; alpha amylase catalytic subunit 7127911..7129890 Actinosynnema mirum DSM 43827 8330282 YP_003103726.1 CDS Amir_6073 NC_013093.1 7129983 7131797 D KEGG: mxa:MXAN_3684 trehalose synthase; TIGRFAM: trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; trehalose synthase 7129983..7131797 Actinosynnema mirum DSM 43827 8330283 YP_003103727.1 CDS Amir_6074 NC_013093.1 7131802 7133130 D PFAM: aminoglycoside phosphotransferase; KEGG: rce:RC1_0516 trehalose synthase; aminoglycoside phosphotransferase 7131802..7133130 Actinosynnema mirum DSM 43827 8330284 YP_003103728.1 CDS Amir_6075 NC_013093.1 7133138 7135606 D KEGG: mxa:MXAN_3682 glycogen branching enzyme; TIGRFAM: 1,4-alpha-glucan branching enzyme; PFAM: alpha amylase all-beta; glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; 1,4-alpha-glucan branching protein 7133138..7135606 Actinosynnema mirum DSM 43827 8330285 YP_003103729.1 CDS Amir_6076 NC_013093.1 7135719 7137104 D KEGG: mno:Mnod_6074 protein of unknown function zinc metallopeptidase; metalloprotease-like protein 7135719..7137104 Actinosynnema mirum DSM 43827 8330286 YP_003103730.1 CDS Amir_6077 NC_013093.1 7137110 7137697 R hypothetical protein complement(7137110..7137697) Actinosynnema mirum DSM 43827 8330287 YP_003103731.1 CDS Amir_6078 NC_013093.1 7137917 7139365 D PFAM: protein of unknown function zinc metallopeptidase KEGG: aba:Acid345_4616 protein of unknown function, zinc metallopeptidase; hypothetical protein 7137917..7139365 Actinosynnema mirum DSM 43827 8330288 YP_003103732.1 CDS Amir_6079 NC_013093.1 7139477 7140457 R PFAM: Thioredoxin domain; KEGG: trx; thioredoxin; K05838 thioredoxin; thioredoxin domain-containing protein complement(7139477..7140457) Actinosynnema mirum DSM 43827 8330289 YP_003103733.1 CDS Amir_6080 NC_013093.1 7140479 7141618 R KEGG: bpd:BURPS668_A3050 hypothetical protein; hypothetical protein complement(7140479..7141618) Actinosynnema mirum DSM 43827 8330290 YP_003103734.1 CDS Amir_6081 NC_013093.1 7141615 7141947 R PFAM: protein of unknown function DUF77; KEGG: mgm:Mmc1_2182 protein of unknown function DUF77; hypothetical protein complement(7141615..7141947) Actinosynnema mirum DSM 43827 8330291 YP_003103735.1 CDS Amir_6082 NC_013093.1 7141994 7142497 D PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: bcz:BCZK0946 MarR family transcriptional regulator; MarR family transcriptional regulator 7141994..7142497 Actinosynnema mirum DSM 43827 8330292 YP_003103736.1 CDS Amir_6083 NC_013093.1 7143088 7144179 D PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce2125 hypothetical protein; aminoglycoside phosphotransferase 7143088..7144179 Actinosynnema mirum DSM 43827 8330293 YP_003103737.1 CDS Amir_6084 NC_013093.1 7144152 7144526 R KEGG: smt:Smal_2278 inner membrane protein; hypothetical protein complement(7144152..7144526) Actinosynnema mirum DSM 43827 8330294 YP_003103738.1 CDS Amir_6085 NC_013093.1 7144523 7145461 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce5573 ABC transporter ATP- binding protein; ABC transporter complement(7144523..7145461) Actinosynnema mirum DSM 43827 8330295 YP_003103739.1 CDS Amir_6086 NC_013093.1 7145799 7146026 D hypothetical protein 7145799..7146026 Actinosynnema mirum DSM 43827 8330296 YP_003103740.1 CDS Amir_6087 NC_013093.1 7146005 7146847 R PFAM: transposase IS4 family protein; KEGG: similar to F57G4.9; transposase IS4 family protein complement(7146005..7146847) Actinosynnema mirum DSM 43827 8330297 YP_003103741.1 CDS Amir_6088 NC_013093.1 7146939 7147112 D hypothetical protein 7146939..7147112 Actinosynnema mirum DSM 43827 8330298 YP_003103742.1 CDS Amir_6089 NC_013093.1 7147130 7147651 D hypothetical protein 7147130..7147651 Actinosynnema mirum DSM 43827 8330299 YP_003103743.1 CDS Amir_6090 NC_013093.1 7147746 7148789 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: smd:Smed_4315 periplasmic binding protein/LacI transcriptional regulator; LacI family transcriptional regulator 7147746..7148789 Actinosynnema mirum DSM 43827 8330300 YP_003103744.1 CDS Amir_6091 NC_013093.1 7148786 7149805 D KEGG: hypothetical protein; hypothetical protein 7148786..7149805 Actinosynnema mirum DSM 43827 8330301 YP_003103745.1 CDS Amir_6092 NC_013093.1 7149807 7150568 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: smd:Smed_0345 ABC transporter; ABC transporter 7149807..7150568 Actinosynnema mirum DSM 43827 8330302 YP_003103746.1 CDS Amir_6093 NC_013093.1 7150565 7151599 D PFAM: inner-membrane translocator; KEGG: smd:Smed_0344 monosaccharide-transporting ATPase; Monosaccharide-transporting ATPase 7150565..7151599 Actinosynnema mirum DSM 43827 8330303 YP_003103747.1 CDS Amir_6094 NC_013093.1 7151619 7152590 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rbsB; ABC transporter substrate binding protein (ribose); K10439 ribose transport system substrate-binding protein; LacI family transcriptional regulator 7151619..7152590 Actinosynnema mirum DSM 43827 8330304 YP_003103748.1 CDS Amir_6095 NC_013093.1 7152661 7153632 R KEGG: hne:HNE_0316 hypothetical protein; hypothetical protein complement(7152661..7153632) Actinosynnema mirum DSM 43827 8330305 YP_003103749.1 CDS Amir_6096 NC_013093.1 7153801 7155474 D PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein 7153801..7155474 Actinosynnema mirum DSM 43827 8330306 YP_003103750.1 CDS Amir_6097 NC_013093.1 7155602 7157281 D PFAM: TAP domain protein; alpha/beta hydrolase fold; KEGG: bph:Bphy_7397 TAP domain-containing protein; TAP domain-containing protein 7155602..7157281 Actinosynnema mirum DSM 43827 8330307 YP_003103751.1 CDS Amir_6098 NC_013093.1 7157747 7158403 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: bsu:BSU33080 hypothetical protein; LuxR family transcriptional regulator complement(7157747..7158403) Actinosynnema mirum DSM 43827 8330308 YP_003103752.1 CDS Amir_6099 NC_013093.1 7158441 7160018 R PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; KEGG: bce:BC2216 two-component sensor protein YhcY; GAF sensor signal transduction histidine kinase complement(7158441..7160018) Actinosynnema mirum DSM 43827 8330309 YP_003103753.1 CDS Amir_6100 NC_013093.1 7160015 7160419 R hypothetical protein complement(7160015..7160419) Actinosynnema mirum DSM 43827 8330310 YP_003103754.1 CDS Amir_6101 NC_013093.1 7160563 7161417 D PFAM: N-acetyltransferase; KEGG: nar:Saro_0952 N-acetyltransferase; N-acetyltransferase 7160563..7161417 Actinosynnema mirum DSM 43827 8330311 YP_003103755.1 CDS Amir_6102 NC_013093.1 7161556 7162110 R hypothetical protein complement(7161556..7162110) Actinosynnema mirum DSM 43827 8330312 YP_003103756.1 CDS Amir_6103 NC_013093.1 7162173 7162751 R hypothetical protein complement(7162173..7162751) Actinosynnema mirum DSM 43827 8330313 YP_003103757.1 CDS Amir_6104 NC_013093.1 7162904 7164097 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(7162904..7164097) Actinosynnema mirum DSM 43827 8330314 YP_003103758.1 CDS Amir_6105 NC_013093.1 7164223 7164663 D TIGRFAM: methylmalonyl-CoA epimerase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: gbm:Gbem_0558 methylmalonyl-CoA epimerase; methylmalonyl-CoA epimerase 7164223..7164663 Actinosynnema mirum DSM 43827 8330315 YP_003103759.1 CDS Amir_6106 NC_013093.1 7164843 7166150 D KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein 7164843..7166150 Actinosynnema mirum DSM 43827 8330316 YP_003103760.1 CDS Amir_6107 NC_013093.1 7166325 7167020 R PFAM: alpha/beta hydrolase fold; KEGG: mxa:MXAN_3278 hydrolase, alpha/beta fold family; alpha/beta hydrolase fold protein complement(7166325..7167020) Actinosynnema mirum DSM 43827 8330317 YP_003103761.1 CDS Amir_6108 NC_013093.1 7167060 7167590 D PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_4010 acetyltransferase, GNAT family; GCN5-like N-acetyltransferase 7167060..7167590 Actinosynnema mirum DSM 43827 8330318 YP_003103762.1 CDS Amir_6109 NC_013093.1 7167631 7167963 R hypothetical protein complement(7167631..7167963) Actinosynnema mirum DSM 43827 8330319 YP_003103763.1 CDS Amir_6110 NC_013093.1 7168081 7168290 D TIGRFAM: regulatory protein, FmdB family; KEGG: mgm:Mmc1_2457 regulatory protein, FmdB family; FmdB family regulatory protein 7168081..7168290 Actinosynnema mirum DSM 43827 8330320 YP_003103764.1 CDS Amir_6111 NC_013093.1 7168381 7168944 R hypothetical protein complement(7168381..7168944) Actinosynnema mirum DSM 43827 8330321 YP_003103765.1 CDS Amir_6112 NC_013093.1 7169121 7169861 R TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; KEGG: dde:Dde_1180 phosphoenolpyruvate--protein phosphotransferase; dihydroxyacetone kinase, phosphotransfer subunit complement(7169121..7169861) Actinosynnema mirum DSM 43827 8330322 YP_003103766.1 CDS Amir_6113 NC_013093.1 7169873 7170499 R TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: gdi:GDI0264 PTS-dependent dihydroxyacetone kinase; dihydroxyacetone kinase, L subunit complement(7169873..7170499) Actinosynnema mirum DSM 43827 8330323 YP_003103767.1 CDS Amir_6114 NC_013093.1 7170499 7171500 R KEGG: gdj:Gdia_2328 dihydroxyacetone kinase, DhaK subunit; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase; dihydroxyacetone kinase, DhaK subunit complement(7170499..7171500) Actinosynnema mirum DSM 43827 8330324 YP_003103768.1 CDS Amir_6115 NC_013093.1 7171665 7173170 R PFAM: Aldehyde Dehydrogenase; KEGG: aba:Acid345_1443 succinate-semialdehyde dehydrogenase (NAD(P)+); aldehyde dehydrogenase complement(7171665..7173170) Actinosynnema mirum DSM 43827 8330325 YP_003103769.1 CDS Amir_6116 NC_013093.1 7173238 7174299 R hypothetical protein complement(7173238..7174299) Actinosynnema mirum DSM 43827 8330326 YP_003103770.1 CDS Amir_6117 NC_013093.1 7174348 7174626 R hypothetical protein complement(7174348..7174626) Actinosynnema mirum DSM 43827 8330327 YP_003103771.1 CDS Amir_6118 NC_013093.1 7174636 7176324 R TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: sus:Acid_3843 SSS family solute/sodium (Na+) symporter; SSS sodium solute transporter superfamily protein complement(7174636..7176324) Actinosynnema mirum DSM 43827 8330328 YP_003103772.1 CDS Amir_6119 NC_013093.1 7176403 7177140 D hypothetical protein 7176403..7177140 Actinosynnema mirum DSM 43827 8330329 YP_003103773.1 CDS Amir_6120 NC_013093.1 7177164 7177493 R hypothetical protein complement(7177164..7177493) Actinosynnema mirum DSM 43827 8330330 YP_003103774.1 CDS Amir_6121 NC_013093.1 7177713 7178570 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bra:BRADO4105 transcriptional regulator; XRE family transcriptional regulator 7177713..7178570 Actinosynnema mirum DSM 43827 8330331 YP_003103775.1 CDS Amir_6122 NC_013093.1 7178586 7178771 D PFAM: protein of unknown function DUF397; hypothetical protein 7178586..7178771 Actinosynnema mirum DSM 43827 8330332 YP_003103776.1 CDS Amir_6123 NC_013093.1 7178772 7179194 R KEGG: dar:Daro_0441 dihydrolipoamide acetyltransferase; dihydrolipoamide acetyltransferase complement(7178772..7179194) Actinosynnema mirum DSM 43827 8330333 YP_003103777.1 CDS Amir_6124 NC_013093.1 7179369 7180028 R PFAM: protein of unknown function DUF91; KEGG: bvi:Bcep1808_6934 hypothetical protein; hypothetical protein complement(7179369..7180028) Actinosynnema mirum DSM 43827 8330334 YP_003103778.1 CDS Amir_6125 NC_013093.1 7180208 7180744 D PFAM: NUDIX hydrolase; KEGG: gdj:Gdia_2018 NUDIX hydrolase; NUDIX hydrolase 7180208..7180744 Actinosynnema mirum DSM 43827 8330335 YP_003103779.1 CDS Amir_6126 NC_013093.1 7180741 7181331 D PFAM: GCN5-related N-acetyltransferase; KEGG: asa:ASA_2273 acetyltransferase; GCN5-like N-acetyltransferase 7180741..7181331 Actinosynnema mirum DSM 43827 8330336 YP_003103780.1 CDS Amir_6127 NC_013093.1 7181422 7182189 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rfr:Rfer_0608 enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase/isomerase complement(7181422..7182189) Actinosynnema mirum DSM 43827 8330337 YP_003103781.1 CDS Amir_6128 NC_013093.1 7182248 7182778 D PFAM: isochorismatase hydrolase; KEGG: cvi:CV_1320 hypothetical protein; isochorismatase hydrolase 7182248..7182778 Actinosynnema mirum DSM 43827 8330338 YP_003103782.1 CDS Amir_6129 NC_013093.1 7182860 7183156 D hypothetical protein 7182860..7183156 Actinosynnema mirum DSM 43827 8330339 YP_003103783.1 CDS Amir_6130 NC_013093.1 7183273 7183638 D hypothetical protein 7183273..7183638 Actinosynnema mirum DSM 43827 8330340 YP_003103784.1 CDS Amir_6131 NC_013093.1 7183643 7184173 D hypothetical protein 7183643..7184173 Actinosynnema mirum DSM 43827 8330341 YP_003103785.1 CDS Amir_6132 NC_013093.1 7184236 7185492 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(7184236..7185492) Actinosynnema mirum DSM 43827 8330342 YP_003103786.1 CDS Amir_6133 NC_013093.1 7185575 7186147 D TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: mmr:Mmar10_2358 ATP:cob(I)alamin adenosyltransferase; ATP/cobalamin adenosyltransferase 7185575..7186147 Actinosynnema mirum DSM 43827 8330343 YP_003103787.1 CDS Amir_6134 NC_013093.1 7186226 7186660 R hypothetical protein complement(7186226..7186660) Actinosynnema mirum DSM 43827 8330344 YP_003103788.1 CDS atpC NC_013093.1 7186692 7187057 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(7186692..7187057) Actinosynnema mirum DSM 43827 8330345 YP_003103789.1 CDS Amir_6136 NC_013093.1 7187441 7188877 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(7187441..7188877) Actinosynnema mirum DSM 43827 8330346 YP_003103790.1 CDS Amir_6137 NC_013093.1 7188870 7189808 R KEGG: lpc:LPC_3298 F0F1 ATP synthase subunit gamma; TIGRFAM: ATP synthase F1, gamma subunit; PFAM: H+transporting two-sector ATPase gamma subunit; ATP synthase F1 subunit gamma complement(7188870..7189808) Actinosynnema mirum DSM 43827 8330347 YP_003103791.1 CDS Amir_6138 NC_013093.1 7189816 7191462 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(7189816..7191462) Actinosynnema mirum DSM 43827 8330348 YP_003103792.1 CDS Amir_6139 NC_013093.1 7191527 7192354 R TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; KEGG: nwi:Nwi_0429 F0F1 ATP synthase subunit delta; ATP synthase F1 subunit delta complement(7191527..7192354) Actinosynnema mirum DSM 43827 8330349 YP_003103793.1 CDS Amir_6140 NC_013093.1 7192363 7192911 R TIGRFAM: ATP synthase F0, B subunit; PFAM: H+transporting two-sector ATPase B/B' subunit; KEGG: ilo:IL2623 F0F1 ATP synthase subunit B; ATP synthase F0 subunit B complement(7192363..7192911) Actinosynnema mirum DSM 43827 8330350 YP_003103794.1 CDS Amir_6141 NC_013093.1 7192943 7193164 R TIGRFAM: ATP synthase F0, C subunit; PFAM: H+transporting two-sector ATPase C subunit; KEGG: atpH; ATPase III subunit; K02110 F-type H+- transporting ATPase subunit c; ATP synthase F0 subunit C complement(7192943..7193164) Actinosynnema mirum DSM 43827 8330351 YP_003103795.1 CDS Amir_6142 NC_013093.1 7193254 7194105 R TIGRFAM: ATP synthase F0, A subunit; PFAM: H+transporting two-sector ATPase A subunit; KEGG: acp:A2cp1_4495 ATP synthase F0, A subunit; ATP synthase F0 subunit A complement(7193254..7194105) Actinosynnema mirum DSM 43827 8330352 YP_003103796.1 CDS Amir_6143 NC_013093.1 7194083 7194292 R hypothetical protein complement(7194083..7194292) Actinosynnema mirum DSM 43827 8330353 YP_003103797.1 CDS Amir_6144 NC_013093.1 7194339 7194716 R hypothetical protein complement(7194339..7194716) Actinosynnema mirum DSM 43827 8330354 YP_003103798.1 CDS Amir_6145 NC_013093.1 7195245 7196414 R PFAM: glycosyl transferase family 4; KEGG: afw:Anae109_4433 glycosyl transferase family protein; glycosyl transferase family protein complement(7195245..7196414) Actinosynnema mirum DSM 43827 8330355 YP_003103799.1 CDS Amir_6146 NC_013093.1 7196486 7197136 R TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: bca:BCE_5452 SUA5/YciO/YrdC/YwlC family protein; Sua5/YciO/YrdC/YwlC family protein complement(7196486..7197136) Actinosynnema mirum DSM 43827 8330356 YP_003103800.1 CDS Amir_6147 NC_013093.1 7197999 7198865 R TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: rce:RC1_2636 modification methylase,HemK family; modification methylase, HemK family complement(7197999..7198865) Actinosynnema mirum DSM 43827 8330357 YP_003103801.1 CDS Amir_6148 NC_013093.1 7198885 7200270 R E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; dihydrolipoamide dehydrogenase complement(7198885..7200270) Actinosynnema mirum DSM 43827 8330358 YP_003103802.1 CDS Amir_6149 NC_013093.1 7200631 7202742 R PFAM: BAAT/acyl-CoA thioester hydrolase; acyl-CoA thioester hydrolase/bile acid-CoA amino acid N- acetyltransferase; KEGG: sus:Acid_3161 palmitoyl-CoA hydrolase; BAAT/acyl-CoA thioester hydrolase complement(7200631..7202742) Actinosynnema mirum DSM 43827 8330359 YP_003103803.1 CDS Amir_6150 NC_013093.1 7203084 7204148 R TIGRFAM: peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: lip:LI0002 peptide chain release factor 1; peptide chain release factor 1 complement(7203084..7204148) Actinosynnema mirum DSM 43827 8330360 YP_003103804.1 CDS Amir_6151 NC_013093.1 7204231 7204443 R TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; KEGG: tbd:Tbd_0039 50S ribosomal protein L31; 50S ribosomal protein L31 complement(7204231..7204443) Actinosynnema mirum DSM 43827 8330361 YP_003103805.1 CDS Amir_6152 NC_013093.1 7204645 7205103 D KEGG: mes:Meso_0153 chromate transporter, chromate ion transporter (CHR) family; hypothetical protein 7204645..7205103 Actinosynnema mirum DSM 43827 8330362 YP_003103806.1 CDS Amir_6153 NC_013093.1 7205355 7207484 R KEGG: bba:Bd0065 transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; Rho termination factor domain protein; Rho termination factor RNA-binding; SMART: ATPase AAA; Cold shock protein; transcription termination factor Rho complement(7205355..7207484) Actinosynnema mirum DSM 43827 8330363 YP_003103807.1 CDS Amir_6154 NC_013093.1 7207826 7208713 R KEGG: sus:Acid_0902 homoserine kinase; TIGRFAM: homoserine kinase; PFAM: GHMP kinase; GHMP kinase domain protein; homoserine kinase complement(7207826..7208713) Actinosynnema mirum DSM 43827 8330364 YP_003103808.1 CDS Amir_6155 NC_013093.1 7208710 7209786 R TIGRFAM: threonine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tgr:Tgr7_1440 threonine synthase; threonine synthase complement(7208710..7209786) Actinosynnema mirum DSM 43827 8330365 YP_003103809.1 CDS Amir_6156 NC_013093.1 7209783 7211096 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(7209783..7211096) Actinosynnema mirum DSM 43827 8330366 YP_003103810.1 CDS Amir_6157 NC_013093.1 7211099 7212523 R TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: bsu:BSU23380 diaminopimelate decarboxylase; diaminopimelate decarboxylase complement(7211099..7212523) Actinosynnema mirum DSM 43827 8330367 YP_003103811.1 CDS argS NC_013093.1 7212523 7214175 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(7212523..7214175) Actinosynnema mirum DSM 43827 8330368 YP_003103812.1 CDS Amir_6159 NC_013093.1 7214355 7215224 D KEGG: scl:sce2901 hypothetical protein; hypothetical protein 7214355..7215224 Actinosynnema mirum DSM 43827 8330369 YP_003103813.1 CDS Amir_6160 NC_013093.1 7215226 7215987 D PFAM: protein of unknown function DUF305; KEGG: mmr:Mmar10_0047 hypothetical protein; hypothetical protein 7215226..7215987 Actinosynnema mirum DSM 43827 8330370 YP_003103814.1 CDS Amir_6161 NC_013093.1 7216436 7220716 D TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; coagulation factor 5/8 type domain protein; KEGG: sml:Smlt3935 glycosyltransferase; alpha-1,2-mannosidase 7216436..7220716 Actinosynnema mirum DSM 43827 8330371 YP_003103815.1 CDS Amir_6162 NC_013093.1 7220737 7221666 R TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mpo:Mpop_4086 cation diffusion facilitator family transporter; cation diffusion facilitator family transporter complement(7220737..7221666) Actinosynnema mirum DSM 43827 8330372 YP_003103816.1 CDS Amir_6163 NC_013093.1 7222001 7223782 R PFAM: protein of unknown function DUF262; KEGG: xau:Xaut_2248 hypothetical protein; hypothetical protein complement(7222001..7223782) Actinosynnema mirum DSM 43827 8330374 YP_003103817.1 CDS Amir_6164 NC_013093.1 7223880 7225718 R PFAM: glycoside hydrolase family 5; KEGG: pla:Plav_0833 hypothetical protein; glycoside hydrolase family protein complement(7223880..7225718) Actinosynnema mirum DSM 43827 8330375 YP_003103818.1 CDS Amir_6165 NC_013093.1 7225870 7227819 R hypothetical protein complement(7225870..7227819) Actinosynnema mirum DSM 43827 8330376 YP_003103819.1 CDS Amir_6166 NC_013093.1 7228008 7231118 R PFAM: transcriptional activator domain; transcriptional regulator domain protein; SMART: ATPase AAA; KEGG: sus:Acid_5780 serine/threonine protein kinase; SARP family transcriptional regulator complement(7228008..7231118) Actinosynnema mirum DSM 43827 8330377 YP_003103820.1 CDS Amir_6167 NC_013093.1 7231247 7232116 D PFAM: alpha/beta hydrolase fold; KEGG: azo:azo0046 haloacetate dehalogenase; alpha/beta hydrolase fold protein 7231247..7232116 Actinosynnema mirum DSM 43827 8330378 YP_003103821.1 CDS Amir_6168 NC_013093.1 7232705 7233124 R SMART: helix-turn-helix domain protein; XRE family transcriptional regulator complement(7232705..7233124) Actinosynnema mirum DSM 43827 8330379 YP_003103822.1 CDS Amir_6169 NC_013093.1 7233262 7233492 D hypothetical protein 7233262..7233492 Actinosynnema mirum DSM 43827 8330380 YP_003103823.1 CDS Amir_6170 NC_013093.1 7233882 7234148 D hypothetical protein 7233882..7234148 Actinosynnema mirum DSM 43827 8330381 YP_003103824.1 CDS Amir_6171 NC_013093.1 7234196 7235281 R KEGG: mca:MCA0835 fic family protein; hypothetical protein complement(7234196..7235281) Actinosynnema mirum DSM 43827 8330382 YP_003103825.1 CDS Amir_6172 NC_013093.1 7235501 7236061 R PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: mlo:mll5358 hypothetical protein; Activator of Hsp90 ATPase 1 family protein complement(7235501..7236061) Actinosynnema mirum DSM 43827 8330383 YP_003103826.1 CDS Amir_6173 NC_013093.1 7236310 7236786 D PFAM: transcription activator effector binding; KEGG: aav:Aave_4607 transcription activator, effector binding; transcriptional activator ligand binding domain-containing protein 7236310..7236786 Actinosynnema mirum DSM 43827 8330384 YP_003103827.1 CDS Amir_6174 NC_013093.1 7236935 7237816 D PFAM: luciferase-like monooxygenase; KEGG: pla:Plav_0210 luciferase family protein; luciferase-like monooxygenase 7236935..7237816 Actinosynnema mirum DSM 43827 8330385 YP_003103828.1 CDS Amir_6175 NC_013093.1 7237910 7238944 R PFAM: GTPase EngC; SMART: ATPase AAA; KEGG: gsu:GSU2530 GTPase YjeQ; GTPase EngC complement(7237910..7238944) Actinosynnema mirum DSM 43827 8330386 YP_003103829.1 CDS Amir_6176 NC_013093.1 7239655 7239750 D hypothetical protein 7239655..7239750 Actinosynnema mirum DSM 43827 8330387 YP_003103830.1 CDS Amir_6177 NC_013093.1 7239815 7240942 D PFAM: nitroreductase; KEGG: bcz:pE33L466_0413 NADH oxidase; nitroreductase 7239815..7240942 Actinosynnema mirum DSM 43827 8330388 YP_003103831.1 CDS Amir_6178 NC_013093.1 7240986 7241966 R PFAM: aldo/keto reductase; KEGG: stm:STM2406 oxidoreductase; aldo/keto reductase complement(7240986..7241966) Actinosynnema mirum DSM 43827 8330389 YP_003103832.1 CDS Amir_6179 NC_013093.1 7241974 7242828 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: scl:sce0662 LacI family transcription regulator; LacI family transcriptional regulator complement(7241974..7242828) Actinosynnema mirum DSM 43827 8330390 YP_003103833.1 CDS Amir_6180 NC_013093.1 7242825 7245263 R KEGG: ret:RHE_CH00480 beta-mannosidase protein; beta-mannosidase protein complement(7242825..7245263) Actinosynnema mirum DSM 43827 8330391 YP_003103834.1 CDS Amir_6181 NC_013093.1 7245381 7247504 D PFAM: glycoside hydrolase clan GH-D; KEGG: esa:ESA_03854 hypothetical protein; glycoside hydrolase family protein 7245381..7247504 Actinosynnema mirum DSM 43827 8330392 YP_003103835.1 CDS Amir_6183 NC_013093.1 7247976 7248356 D KEGG: cvi:CV_1450 hypothetical protein; hypothetical protein 7247976..7248356 Actinosynnema mirum DSM 43827 8330394 YP_003103836.1 CDS Amir_6185 NC_013093.1 7248654 7249511 R PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: vsp:VS_II1529 ABC systems: ATP-binding protein; ABC transporter complement(7248654..7249511) Actinosynnema mirum DSM 43827 8330396 YP_003103837.1 CDS Amir_6186 NC_013093.1 7249508 7251280 R PFAM: ABC transporter; binding-protein- dependent transport systems inner membrane component; SMART: ATPase AAA; KEGG: mxa:MXAN_6553 oligopeptide/dipeptide ABC transporter, permease/ATP-binding protein; ABC transporter complement(7249508..7251280) Actinosynnema mirum DSM 43827 8330397 YP_003103838.1 CDS Amir_6187 NC_013093.1 7251294 7252283 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: scl:sce4301 peptide ABC transporter, permease protein; ABC transporter inner membrane protein complement(7251294..7252283) Actinosynnema mirum DSM 43827 8330398 YP_003103839.1 CDS Amir_6188 NC_013093.1 7252288 7253970 R PFAM: extracellular solute-binding protein family 5; KEGG: scl:sce4302 ABC-type dipeptide transport system, periplasmic component; family 5 extracellular solute-binding protein complement(7252288..7253970) Actinosynnema mirum DSM 43827 8330399 YP_003103840.1 CDS Amir_6189 NC_013093.1 7254148 7255356 D PFAM: ROK family protein; KEGG: mxa:MXAN_6549 transcriptional regulator, ROK family; ROK family protein 7254148..7255356 Actinosynnema mirum DSM 43827 8330400 YP_003103841.1 CDS Amir_6190 NC_013093.1 7255414 7255536 R hypothetical protein complement(7255414..7255536) Actinosynnema mirum DSM 43827 8330401 YP_003103842.1 CDS Amir_6191 NC_013093.1 7255777 7257063 R KEGG: bav:BAV1845 monooxygenase; monooxygenase complement(7255777..7257063) Actinosynnema mirum DSM 43827 8330402 YP_003103843.1 CDS Amir_6192 NC_013093.1 7257063 7258151 R KEGG: bav:BAV1846 monooxygenase; monooxygenase complement(7257063..7258151) Actinosynnema mirum DSM 43827 8330403 YP_003103844.1 CDS Amir_6193 NC_013093.1 7258238 7259296 R PFAM: FAD dependent oxidoreductase; KEGG: sus:Acid_5898 N-methyltryptophan oxidase; Sarcosine oxidase complement(7258238..7259296) Actinosynnema mirum DSM 43827 8330404 YP_003103845.1 CDS Amir_6194 NC_013093.1 7259436 7260221 R TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: ppd:Ppro_3005 HemK family modification methylase; modification methylase, HemK family complement(7259436..7260221) Actinosynnema mirum DSM 43827 8330405 YP_003103846.1 CDS Amir_6195 NC_013093.1 7260387 7261649 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: scl:sce6417 ECF subfamily RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit complement(7260387..7261649) Actinosynnema mirum DSM 43827 8330406 YP_003103847.1 CDS Amir_6196 NC_013093.1 7261740 7262162 R PFAM: YCII-related; KEGG: bmj:BMULJ_04986 hypothetical protein; YCII-like protein complement(7261740..7262162) Actinosynnema mirum DSM 43827 8330407 YP_003103848.1 CDS Amir_6197 NC_013093.1 7262316 7263008 R SMART: helix-turn-helix- domain containing protein AraC type; KEGG: scl:sce0732 AraC family transcriptional regulator; AraC family transcriptional regulator complement(7262316..7263008) Actinosynnema mirum DSM 43827 8330408 YP_003103849.1 CDS Amir_6198 NC_013093.1 7263074 7263826 D PFAM: NmrA family protein; KEGG: scl:sce0731 hypothetical protein; NmrA family protein 7263074..7263826 Actinosynnema mirum DSM 43827 8330409 YP_003103850.1 CDS Amir_6199 NC_013093.1 7263814 7265091 R KEGG: pzu:PHZ_c3387 hypothetical protein; PEP phosphonomutase-like protein complement(7263814..7265091) Actinosynnema mirum DSM 43827 8330410 YP_003103851.1 CDS Amir_6200 NC_013093.1 7265142 7266098 R PFAM: alcohol dehydrogenase GroES domain protein; KEGG: bxe:Bxe_C0078 zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(7265142..7266098) Actinosynnema mirum DSM 43827 8330411 YP_003103852.1 CDS Amir_6201 NC_013093.1 7266202 7266771 D PFAM: regulatory protein TetR; KEGG: mxa:MXAN_2145 transcriptional regulator, TetR family; TetR family transcriptional regulator 7266202..7266771 Actinosynnema mirum DSM 43827 8330412 YP_003103853.1 CDS Amir_6202 NC_013093.1 7267149 7267982 D SMART: regulatory protein ArsR; KEGG: met:M446_4445 ArsR family transcriptional regulator; ArsR family transcriptional regulator 7267149..7267982 Actinosynnema mirum DSM 43827 8330413 YP_003103854.1 CDS Amir_6203 NC_013093.1 7267989 7268708 R PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: afw:Anae109_3817 protein phosphatase 2C-like protein; protein serine/threonine phosphatase complement(7267989..7268708) Actinosynnema mirum DSM 43827 8330414 YP_003103855.1 CDS Amir_6204 NC_013093.1 7268752 7269804 R PFAM: ROK family protein; KEGG: cvi:CV_2895 transcriptional regulator protein; ROK family protein complement(7268752..7269804) Actinosynnema mirum DSM 43827 8330415 YP_003103856.1 CDS Amir_6205 NC_013093.1 7270095 7271231 R PFAM: beta-lactamase; KEGG: bcb:BCB4264_A3030 alkaline D-peptidase; Serine-type D-Ala-D-Ala carboxypeptidase complement(7270095..7271231) Actinosynnema mirum DSM 43827 8330416 YP_003103857.1 CDS Amir_6206 NC_013093.1 7271505 7273115 D PFAM: glycoside hydrolase family 18; cellulose- binding family II; SMART: chitinase II; cellulose-binding family II; KEGG: cja:CJA_2611 endo-chitinase, , chi18D; glycoside hydrolase family protein 7271505..7273115 Actinosynnema mirum DSM 43827 8330417 YP_003103858.1 CDS Amir_6207 NC_013093.1 7273237 7275414 R KEGG: ppd:Ppro_0186 RecD/TraA family helicase; TIGRFAM: helicase, RecD/TraA family; SMART: ATPase AAA; helicase, RecD/TraA family complement(7273237..7275414) Actinosynnema mirum DSM 43827 8330418 YP_003103859.1 CDS Amir_6208 NC_013093.1 7275747 7276427 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family; winged helix family two component transcriptional regulator 7275747..7276427 Actinosynnema mirum DSM 43827 8330419 YP_003103860.1 CDS Amir_6209 NC_013093.1 7276424 7277455 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: lch:Lcho_2475 histidine kinase; histidine kinase 7276424..7277455 Actinosynnema mirum DSM 43827 8330420 YP_003103861.1 CDS Amir_6210 NC_013093.1 7277556 7279037 D KEGG: pzu:PHZ_c1830 ABC transporter, ATP-binding protein CydD; hypothetical protein 7277556..7279037 Actinosynnema mirum DSM 43827 8330421 YP_003103862.1 CDS Amir_6211 NC_013093.1 7279229 7280404 D PFAM: MscS Mechanosensitive ion channel; KEGG: bac:BamMC406_1797 MscS mechanosensitive ion channel; mechanosensitive ion channel MscS 7279229..7280404 Actinosynnema mirum DSM 43827 8330422 YP_003103863.1 CDS Amir_6212 NC_013093.1 7280443 7280994 D KEGG: swi:Swit_4745 RND family efflux transporter MFP subunit; hypothetical protein 7280443..7280994 Actinosynnema mirum DSM 43827 8330423 YP_003103864.1 CDS Amir_6213 NC_013093.1 7281702 7284941 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: hypothetical protein; peptidase S8/S53 subtilisin kexin sedolisin 7281702..7284941 Actinosynnema mirum DSM 43827 8330424 YP_003103865.1 CDS Amir_6214 NC_013093.1 7285109 7286764 D proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 7285109..7286764 Actinosynnema mirum DSM 43827 8330425 YP_003103866.1 CDS Amir_6215 NC_013093.1 7286799 7287638 R PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: dvu:DVU3313 LysR family transcriptional regulator; LysR family transcriptional regulator complement(7286799..7287638) Actinosynnema mirum DSM 43827 8330426 YP_003103867.1 CDS Amir_6216 NC_013093.1 7287732 7288499 D PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: ccv:CCV52592_0326 NADP oxidoreductase, coenzyme F420-dependent; NADP oxidoreductase coenzyme F420-dependent 7287732..7288499 Actinosynnema mirum DSM 43827 8330427 YP_003103868.1 CDS Amir_6217 NC_013093.1 7288503 7288979 R PFAM: flavin reductase domain protein FMN-binding; KEGG: dac:Daci_0096 flavin reductase domain- containing protein; flavin reductase domain-containing protein complement(7288503..7288979) Actinosynnema mirum DSM 43827 8330428 YP_003103869.1 CDS Amir_6218 NC_013093.1 7289247 7290017 R hypothetical protein complement(7289247..7290017) Actinosynnema mirum DSM 43827 8330429 YP_003103870.1 CDS Amir_6219 NC_013093.1 7290014 7291804 R KEGG: GH21940 gene product from transcript GH21940- RA; hypothetical protein complement(7290014..7291804) Actinosynnema mirum DSM 43827 8330430 YP_003103871.1 CDS Amir_6220 NC_013093.1 7291818 7292267 R hypothetical protein complement(7291818..7292267) Actinosynnema mirum DSM 43827 8330431 YP_003103872.1 CDS Amir_6221 NC_013093.1 7292367 7295162 D PFAM: transcriptional activator domain; hypothetical protein; hypothetical protein; NB- ARC domain protein; transcriptional regulator domain protein; SMART: ATPase AAA; hypothetical protein; KEGG: scl:sce5225 protein kinase; SARP family transcriptional regulator 7292367..7295162 Actinosynnema mirum DSM 43827 8330432 YP_003103873.1 CDS Amir_6222 NC_013093.1 7295607 7297466 R KEGG: hypothetical protein; hypothetical protein complement(7295607..7297466) Actinosynnema mirum DSM 43827 8330433 YP_003103874.1 CDS Amir_6223 NC_013093.1 7298025 7300133 D KEGG: pfl:PFL_0190 sensory box-containing diguanylate cyclase, TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat- containing protein; EAL domain protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase 7298025..7300133 Actinosynnema mirum DSM 43827 8330434 YP_003103875.1 CDS Amir_6224 NC_013093.1 7300267 7301118 D PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: shw:Sputw3181_3433 protease Do; peptidase S1 and S6 chymotrypsin/Hap 7300267..7301118 Actinosynnema mirum DSM 43827 8330435 YP_003103876.1 CDS Amir_6225 NC_013093.1 7301255 7302844 D PFAM: acyl-CoA dehydrogenase domain protein; KEGG: aeh:Mlg_1719 acyl-CoA dehydrogenase domain- containing protein; acyl-CoA dehydrogenase domain-containing protein 7301255..7302844 Actinosynnema mirum DSM 43827 8330436 YP_003103877.1 CDS Amir_6226 NC_013093.1 7302856 7303602 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 7302856..7303602 Actinosynnema mirum DSM 43827 8330437 YP_003103878.1 CDS Amir_6227 NC_013093.1 7303651 7303959 R hypothetical protein complement(7303651..7303959) Actinosynnema mirum DSM 43827 8330438 YP_003103879.1 CDS Amir_6228 NC_013093.1 7303970 7305121 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: reu:Reut_C6425 butyryl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein complement(7303970..7305121) Actinosynnema mirum DSM 43827 8330439 YP_003103880.1 CDS Amir_6229 NC_013093.1 7305127 7307058 R PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; biotin/lipoyl attachment domain-containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: mag:amb0674 acetyl-/propionyl-coenzyme A carboxylase alpha chain; carbamoyl-phosphate synthase L chain ATP- binding complement(7305127..7307058) Actinosynnema mirum DSM 43827 8330440 YP_003103881.1 CDS Amir_6230 NC_013093.1 7307058 7308659 R PFAM: carboxyl transferase; KEGG: bmj:BMULJ_05049 propionyl-CoA carboxylase beta chain; propionyl-CoA carboxylase complement(7307058..7308659) Actinosynnema mirum DSM 43827 8330441 YP_003103882.1 CDS Amir_6231 NC_013093.1 7309015 7309608 D PFAM: regulatory protein TetR; KEGG: reu:Reut_B5488 TetR family transcriptional regulator; TetR family transcriptional regulator 7309015..7309608 Actinosynnema mirum DSM 43827 8330442 YP_003103883.1 CDS Amir_6232 NC_013093.1 7310055 7312226 D KEGG: mxa:MXAN_4195 hypothetical protein; hypothetical protein 7310055..7312226 Actinosynnema mirum DSM 43827 8330443 YP_003103884.1 CDS Amir_6234 NC_013093.1 7313339 7314043 R PFAM: protein of unknown function DUF1023; KEGG: hypothetical protein; hypothetical protein complement(7313339..7314043) Actinosynnema mirum DSM 43827 8330445 YP_003103885.1 CDS Amir_6235 NC_013093.1 7314096 7314743 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(7314096..7314743) Actinosynnema mirum DSM 43827 8330446 YP_003103886.1 CDS Amir_6236 NC_013093.1 7314917 7316080 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(7314917..7316080) Actinosynnema mirum DSM 43827 8330447 YP_003103887.1 CDS Amir_6237 NC_013093.1 7316238 7316738 D hypothetical protein 7316238..7316738 Actinosynnema mirum DSM 43827 8330448 YP_003103888.1 CDS Amir_6238 NC_013093.1 7316946 7318604 D PFAM: cellulose-binding family II; Fibronectin type III domain protein; SMART: cellulose-binding family II; Fibronectin type III domain protein; KEGG: azc:AZC_2901 type III fibronectin; cellulose-binding family protein 7316946..7318604 Actinosynnema mirum DSM 43827 8330449 YP_003103889.1 CDS Amir_6239 NC_013093.1 7318588 7319619 R KEGG: ank:AnaeK_2457 homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; homoserine O-acetyltransferase complement(7318588..7319619) Actinosynnema mirum DSM 43827 8330450 YP_003103890.1 CDS Amir_6240 NC_013093.1 7319616 7320905 R catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase complement(7319616..7320905) Actinosynnema mirum DSM 43827 8330451 YP_003103891.1 CDS Amir_6241 NC_013093.1 7321029 7322027 D PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: scl:sce9140 oxidoreductase; oxidoreductase domain-containing protein 7321029..7322027 Actinosynnema mirum DSM 43827 8330452 YP_003103892.1 CDS Amir_6242 NC_013093.1 7322029 7322373 R hypothetical protein complement(7322029..7322373) Actinosynnema mirum DSM 43827 8330453 YP_003103893.1 CDS Amir_6243 NC_013093.1 7322612 7323298 R hypothetical protein complement(7322612..7323298) Actinosynnema mirum DSM 43827 8330454 YP_003103894.1 CDS Amir_6244 NC_013093.1 7323444 7323863 D PFAM: proteinase inhibitor I16 subtilisin-type inhibitor; proteinase inhibitor I16 subtilisin-type inhibitor 7323444..7323863 Actinosynnema mirum DSM 43827 8330455 YP_003103895.1 CDS Amir_6245 NC_013093.1 7324109 7324600 D PFAM: glutathione peroxidase; KEGG: pap:PSPA7_4682 glutathione peroxidase; glutathione peroxidase 7324109..7324600 Actinosynnema mirum DSM 43827 8330456 YP_003103896.1 CDS Amir_6246 NC_013093.1 7324742 7326109 R KEGG: pap:PSPA7_2808 L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 complement(7324742..7326109) Actinosynnema mirum DSM 43827 8330457 YP_003103897.1 CDS Amir_6247 NC_013093.1 7326113 7326496 R TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; KEGG: bcr:BCAH187_A5133 glycine cleavage system H protein; glycine cleavage system H protein complement(7326113..7326496) Actinosynnema mirum DSM 43827 8330458 YP_003103898.1 CDS Amir_6248 NC_013093.1 7326907 7328013 D KEGG: dar:Daro_2145 L-alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; alanine dehydrogenase 7326907..7328013 Actinosynnema mirum DSM 43827 8330459 YP_003103899.1 CDS Amir_6249 NC_013093.1 7328700 7329122 D hypothetical protein 7328700..7329122 Actinosynnema mirum DSM 43827 8330460 YP_003103900.1 CDS Amir_6250 NC_013093.1 7329173 7330546 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ccs:CCNA_03389 lantibiotic transport ATP- binding protein; ABC transporter 7329173..7330546 Actinosynnema mirum DSM 43827 8330461 YP_003103901.1 CDS Amir_6251 NC_013093.1 7330546 7331421 D hypothetical protein 7330546..7331421 Actinosynnema mirum DSM 43827 8330462 YP_003103902.1 CDS Amir_6252 NC_013093.1 7331430 7335740 D PFAM: ABC transporter; ABC transporter transmembrane protein; SMART: ATPase AAA; KEGG: see:SNSL254_A2969 ATP binding cassette; ABC transporter 7331430..7335740 Actinosynnema mirum DSM 43827 8330463 YP_003103903.1 CDS kgd NC_013093.1 7337165 7340893 D kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase 7337165..7340893 Actinosynnema mirum DSM 43827 8330464 YP_003103904.1 CDS Amir_6254 NC_013093.1 7340900 7341082 D hypothetical protein 7340900..7341082 Actinosynnema mirum DSM 43827 8330465 YP_003103905.1 CDS Amir_6255 NC_013093.1 7341204 7341788 R KEGG: GF17241 gene product from transcript GF17241- RA; hypothetical protein complement(7341204..7341788) Actinosynnema mirum DSM 43827 8330466 YP_003103906.1 CDS Amir_6256 NC_013093.1 7341839 7342843 R PFAM: aldo/keto reductase; KEGG: scl:sce5264 sugar-phosphate dehydrogenase; aldo/keto reductase complement(7341839..7342843) Actinosynnema mirum DSM 43827 8330467 YP_003103907.1 CDS Amir_6257 NC_013093.1 7342888 7343943 R PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; SMART: helix-turn-helix domain protein; KEGG: ppd:Ppro_0104 helix-turn-helix domain- containing protein; helix-turn-helix domain-containing protein complement(7342888..7343943) Actinosynnema mirum DSM 43827 8330468 YP_003103908.1 CDS Amir_6258 NC_013093.1 7343936 7344682 R hypothetical protein complement(7343936..7344682) Actinosynnema mirum DSM 43827 8330469 YP_003103909.1 CDS Amir_6259 NC_013093.1 7344887 7347259 R PFAM: NB-ARC domain protein; KEGG: scl:sce5225 protein kinase; NB-ARC domain-containing protein complement(7344887..7347259) Actinosynnema mirum DSM 43827 8330470 YP_003103910.1 CDS Amir_6260 NC_013093.1 7347256 7347849 R hypothetical protein complement(7347256..7347849) Actinosynnema mirum DSM 43827 8330471 YP_003103911.1 CDS Amir_6261 NC_013093.1 7347846 7348121 R hypothetical protein complement(7347846..7348121) Actinosynnema mirum DSM 43827 8330472 YP_003103912.1 CDS Amir_6262 NC_013093.1 7348314 7349459 R catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase complement(7348314..7349459) Actinosynnema mirum DSM 43827 8330473 YP_003103913.1 CDS Amir_6263 NC_013093.1 7349536 7350825 R TIGRFAM: formiminoglutamate deiminase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: pzu:PHZ_c0464 formiminoglutamate deiminase; formiminoglutamate deiminase complement(7349536..7350825) Actinosynnema mirum DSM 43827 8330474 YP_003103914.1 CDS Amir_6264 NC_013093.1 7350986 7352161 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(7350986..7352161) Actinosynnema mirum DSM 43827 8330475 YP_003103915.1 CDS Amir_6265 NC_013093.1 7352158 7353804 R catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase complement(7352158..7353804) Actinosynnema mirum DSM 43827 8330476 YP_003103916.1 CDS Amir_6266 NC_013093.1 7353798 7355309 R catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase complement(7353798..7355309) Actinosynnema mirum DSM 43827 8330477 YP_003103917.1 CDS Amir_6267 NC_013093.1 7355768 7356547 D PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: cti:RALTA_B0569 transcriptional regulator, IclR family; IclR family transcriptional regulator 7355768..7356547 Actinosynnema mirum DSM 43827 8330478 YP_003103918.1 CDS Amir_6268 NC_013093.1 7356599 7357483 R PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: opuAC; substrate-binding region of ABC-type glycine betaine transport system; glycine/betaine ABC transporter substrate-binding protein complement(7356599..7357483) Actinosynnema mirum DSM 43827 8330479 YP_003103919.1 CDS Amir_6269 NC_013093.1 7357480 7358211 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ABC transporter; K05846 osmoprotectant transport system permease protein; ABC transporter inner membrane protein complement(7357480..7358211) Actinosynnema mirum DSM 43827 8330480 YP_003103920.1 CDS Amir_6270 NC_013093.1 7358208 7358864 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: proline/glycine betaine ABC transporter; K05846 osmoprotectant transport system permease protein; ABC transporter inner membrane protein complement(7358208..7358864) Actinosynnema mirum DSM 43827 8330481 YP_003103921.1 CDS Amir_6271 NC_013093.1 7358857 7359939 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ABC transporter nucleotide binding/ATPase protein (proline/glycine/betaine); ABC transporter complement(7358857..7359939) Actinosynnema mirum DSM 43827 8330482 YP_003103922.1 CDS Amir_6272 NC_013093.1 7360096 7361655 D PFAM: protein of unknown function DUF43; KEGG: rpb:RPB_2044 hypothetical protein; hypothetical protein 7360096..7361655 Actinosynnema mirum DSM 43827 8330483 YP_003103923.1 CDS Amir_6273 NC_013093.1 7361683 7362294 R hypothetical protein complement(7361683..7362294) Actinosynnema mirum DSM 43827 8330484 YP_003103924.1 CDS Amir_6274 NC_013093.1 7362358 7362981 R hypothetical protein complement(7362358..7362981) Actinosynnema mirum DSM 43827 8330485 YP_003103925.1 CDS Amir_6275 NC_013093.1 7362978 7364222 R KEGG: rru:Rru_A3216 hypothetical protein; hypothetical protein complement(7362978..7364222) Actinosynnema mirum DSM 43827 8330486 YP_003103926.1 CDS Amir_6276 NC_013093.1 7364222 7364530 R hypothetical protein complement(7364222..7364530) Actinosynnema mirum DSM 43827 8330487 YP_003103927.1 CDS Amir_6277 NC_013093.1 7364527 7365048 R KEGG: dac:Daci_5082 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(7364527..7365048) Actinosynnema mirum DSM 43827 8330488 YP_003103928.1 CDS Amir_6278 NC_013093.1 7365181 7368375 R KEGG: tbd:Tbd_1456 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase complement(7365181..7368375) Actinosynnema mirum DSM 43827 8330489 YP_003103929.1 CDS Amir_6279 NC_013093.1 7368614 7369792 R PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: bcb:BCB4264_A4713 malate dehydrogenase; malate dehydrogenase complement(7368614..7369792) Actinosynnema mirum DSM 43827 8330490 YP_003103930.1 CDS Amir_6280 NC_013093.1 7370108 7370704 D KEGG: ecw:EcE24377A_2329 dTDP-4-dehydrorhamnose 3,5- epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 7370108..7370704 Actinosynnema mirum DSM 43827 8330491 YP_003103931.1 CDS Amir_6281 NC_013093.1 7370708 7371037 R TIGRFAM: nickel-type superoxide dismutase maturation protease; PFAM: peptidase S24 and S26 domain protein; KEGG: peptidase S24-like domain containing protein; K09647 mitochondrial inner membrane protease subunit 1; phage repressor complement(7370708..7371037) Actinosynnema mirum DSM 43827 8330492 YP_003103932.1 CDS Amir_6282 NC_013093.1 7371115 7371531 D KEGG: mmw:Mmwyl1_1415 superoxide dismutase Ni-type; TIGRFAM: superoxide dismutase, Ni; PFAM: superoxide dismutase Ni-type; superoxide dismutase, Ni 7371115..7371531 Actinosynnema mirum DSM 43827 8330493 YP_003103933.1 CDS Amir_6283 NC_013093.1 7371611 7372714 R KEGG: bur:Bcep18194_B0516 hypothetical protein; hypothetical protein complement(7371611..7372714) Actinosynnema mirum DSM 43827 8330494 YP_003103934.1 CDS Amir_6284 NC_013093.1 7372905 7373513 D PFAM: phosphoglycerate mutase; KEGG: rle:RL0954 phosphoglycerate mutase; phosphoglycerate mutase 7372905..7373513 Actinosynnema mirum DSM 43827 8330495 YP_003103935.1 CDS Amir_6285 NC_013093.1 7373630 7374421 R PFAM: protein of unknown function DUF574; KEGG: mxa:MXAN_2293 hypothetical protein; hypothetical protein complement(7373630..7374421) Actinosynnema mirum DSM 43827 8330496 YP_003103936.1 CDS Amir_6286 NC_013093.1 7375145 7375897 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: scl:sce6803 serine protease; peptidase S1 and S6 chymotrypsin/Hap complement(7375145..7375897) Actinosynnema mirum DSM 43827 8330497 YP_003103937.1 CDS Amir_6287 NC_013093.1 7376046 7376447 R hypothetical protein complement(7376046..7376447) Actinosynnema mirum DSM 43827 8330498 YP_003103938.1 CDS Amir_6288 NC_013093.1 7376704 7377681 D PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; KEGG: mag:amb0267 Sphingosine kinase and enzyme related to diacylglycerol kinase; diacylglycerol kinase catalytic subunit 7376704..7377681 Actinosynnema mirum DSM 43827 8330499 YP_003103939.1 CDS Amir_6289 NC_013093.1 7377909 7378163 D PFAM: transcription factor WhiB; transcription factor WhiB 7377909..7378163 Actinosynnema mirum DSM 43827 8330500 YP_003103940.1 CDS Amir_6290 NC_013093.1 7378472 7379950 R PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: pca:Pcar_2710 hypothetical protein; signal transduction histidine kinase complement(7378472..7379950) Actinosynnema mirum DSM 43827 8330501 YP_003103941.1 CDS Amir_6291 NC_013093.1 7380328 7380720 R TIGRFAM: anti-sigma factor; KEGG: tgr:Tgr7_1713 transmembrane anti- sigma factor; anti-sigma factor complement(7380328..7380720) Actinosynnema mirum DSM 43827 8330502 YP_003103942.1 CDS Amir_6292 NC_013093.1 7380717 7381376 R TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: scl:sce7566 ECF family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit complement(7380717..7381376) Actinosynnema mirum DSM 43827 8330503 YP_003103943.1 CDS Amir_6293 NC_013093.1 7381569 7382051 D TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: hch:HCH_01964 hypothetical protein; ybaK/ebsC protein 7381569..7382051 Actinosynnema mirum DSM 43827 8330504 YP_003103944.1 CDS Amir_6294 NC_013093.1 7382135 7382749 R KEGG: rle:pRL110093 hypothetical protein; hypothetical protein complement(7382135..7382749) Actinosynnema mirum DSM 43827 8330505 YP_003103945.1 CDS Amir_6295 NC_013093.1 7382746 7383507 R PFAM: protein of unknown function DUF159; KEGG: dal:Dalk_1121 protein of unknown function DUF159; hypothetical protein complement(7382746..7383507) Actinosynnema mirum DSM 43827 8330506 YP_003103946.1 CDS Amir_6296 NC_013093.1 7383590 7384852 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 7383590..7384852 Actinosynnema mirum DSM 43827 8330507 YP_003103947.1 CDS Amir_6297 NC_013093.1 7384854 7385861 D PFAM: GTPase EngC; KEGG: cvi:CV_2365 ribosome-associated GTPase; GTPase EngC 7384854..7385861 Actinosynnema mirum DSM 43827 8330508 YP_003103948.1 CDS Amir_6298 NC_013093.1 7385998 7386375 D PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: slo:Shew_2437 hypothetical protein; glyoxalase/bleomycin resistance protein/dioxygenase 7385998..7386375 Actinosynnema mirum DSM 43827 8330509 YP_003103949.1 CDS Amir_6299 NC_013093.1 7386397 7386906 R hypothetical protein complement(7386397..7386906) Actinosynnema mirum DSM 43827 8330510 YP_003103950.1 CDS Amir_6300 NC_013093.1 7386903 7388291 R TIGRFAM: acyltransferase, WS/DGAT/MGAT; PFAM: protein of unknown function UPF0089; KEGG: maq:Maqu_3067 hypothetical protein; acyltransferase, WS/DGAT/MGAT complement(7386903..7388291) Actinosynnema mirum DSM 43827 8330511 YP_003103951.1 CDS Amir_6301 NC_013093.1 7388301 7388972 R PFAM: aminoglycoside phosphotransferase; KEGG: mch:Mchl_2091 aminoglycoside phosphotransferase; Mn2+dependent serine/threonine protein kinase complement(7388301..7388972) Actinosynnema mirum DSM 43827 8330512 YP_003103952.1 CDS Amir_6302 NC_013093.1 7389059 7389805 D TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sde:Sde_1711 von Willebrand factor, type A; TrmH family RNA methyltransferase 7389059..7389805 Actinosynnema mirum DSM 43827 8330513 YP_003103953.1 CDS Amir_6303 NC_013093.1 7390196 7390597 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: ACAD10; acyl-Coenzyme A dehydrogenase family, member 10; K11729 acyl-CoA dehydrogenase family member 10; HAD superfamily hydrolase complement(7390196..7390597) Actinosynnema mirum DSM 43827 8330514 YP_003103954.1 CDS Amir_6304 NC_013093.1 7390663 7391040 D hypothetical protein 7390663..7391040 Actinosynnema mirum DSM 43827 8330515 YP_003103955.1 CDS Amir_6305 NC_013093.1 7391532 7394459 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(7391532..7394459) Actinosynnema mirum DSM 43827 8330516 YP_003103956.1 CDS Amir_6306 NC_013093.1 7395702 7396370 R TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: probable plastid-specific ribosomal protein PSRP-1 precursor; sigma 54 modulation protein/30S ribosomal protein S30EA complement(7395702..7396370) Actinosynnema mirum DSM 43827 8330517 YP_003103957.1 CDS Amir_6307 NC_013093.1 7396812 7397432 R KEGG: acp:A2cp1_0258 phosphoribosyltransferase; phosphoribosyltransferase complement(7396812..7397432) Actinosynnema mirum DSM 43827 8330518 YP_003103958.1 CDS Amir_6308 NC_013093.1 7397640 7399373 R KEGG: efe:EFER_0542 adhesin for cattle intestine colonization; hypothetical protein complement(7397640..7399373) Actinosynnema mirum DSM 43827 8330519 YP_003103959.1 CDS Amir_6309 NC_013093.1 7399370 7401775 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase; histidine kinase complement(7399370..7401775) Actinosynnema mirum DSM 43827 8330520 YP_003103960.1 CDS Amir_6310 NC_013093.1 7401810 7402595 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator; winged helix family two component transcriptional regulator complement(7401810..7402595) Actinosynnema mirum DSM 43827 8330521 YP_003103961.1 CDS Amir_6311 NC_013093.1 7402688 7403320 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(7402688..7403320) Actinosynnema mirum DSM 43827 8330522 YP_003103962.1 CDS Amir_6312 NC_013093.1 7403398 7403622 R PFAM: protein of unknown function DUF397; hypothetical protein complement(7403398..7403622) Actinosynnema mirum DSM 43827 8330523 YP_003103963.1 CDS Amir_6313 NC_013093.1 7403643 7404527 R hypothetical protein complement(7403643..7404527) Actinosynnema mirum DSM 43827 8330524 YP_003103964.1 CDS Amir_6315 NC_013093.1 7405071 7405238 D hypothetical protein 7405071..7405238 Actinosynnema mirum DSM 43827 8330526 YP_003103965.1 CDS Amir_6316 NC_013093.1 7405310 7407139 D PFAM: asparagine synthase; KEGG: swi:Swit_4548 asparagine synthase; asparagine synthase 7405310..7407139 Actinosynnema mirum DSM 43827 8330527 YP_003103966.1 CDS Amir_6317 NC_013093.1 7407136 7407900 D KEGG: ank:AnaeK_0240 FAD dependent oxidoreductase; hypothetical protein 7407136..7407900 Actinosynnema mirum DSM 43827 8330528 YP_003103967.1 CDS Amir_6318 NC_013093.1 7407897 7408487 D PFAM: GCN5-related N-acetyltransferase; KEGG: vch:VCA0417 acetyltransferase; GCN5-like N-acetyltransferase 7407897..7408487 Actinosynnema mirum DSM 43827 8330529 YP_003103968.1 CDS Amir_6320 NC_013093.1 7409428 7410336 D hypothetical protein 7409428..7410336 Actinosynnema mirum DSM 43827 8330531 YP_003103969.1 CDS Amir_6321 NC_013093.1 7410398 7411870 R catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase complement(7410398..7411870) Actinosynnema mirum DSM 43827 8330532 YP_003103970.1 CDS Amir_6322 NC_013093.1 7412046 7413557 R PFAM: amino acid permease-associated region; aromatic amino acid permease; KEGG: rpi:Rpic_1962 amino acid permease-associated region; amino acid permease-associated protein complement(7412046..7413557) Actinosynnema mirum DSM 43827 8330533 YP_003103971.1 CDS Amir_6323 NC_013093.1 7413627 7414544 R TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: hch:HCH_04023 Co/Zn/Cd cation transporter; cation diffusion facilitator family transporter complement(7413627..7414544) Actinosynnema mirum DSM 43827 8330534 YP_003103972.1 CDS Amir_6324 NC_013093.1 7414605 7415828 R TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: scl:sce4699 mannose-6-phosphate isomerase; mannose-6-phosphate isomerase, class I complement(7414605..7415828) Actinosynnema mirum DSM 43827 8330535 YP_003103973.1 CDS Amir_6325 NC_013093.1 7415949 7417025 R KEGG: mch:Mchl_4903 double-strand break repair protein AddB; hypothetical protein complement(7415949..7417025) Actinosynnema mirum DSM 43827 8330536 YP_003103974.1 CDS Amir_6326 NC_013093.1 7417032 7417223 R PFAM: protein of unknown function DUF343; KEGG: mes:Meso_3270 protein of unknown function DUF343; hypothetical protein complement(7417032..7417223) Actinosynnema mirum DSM 43827 8330537 YP_003103975.1 CDS manB NC_013093.1 7417251 7418603 R converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase/phosphoglucomutase complement(7417251..7418603) Actinosynnema mirum DSM 43827 8330538 YP_003103976.1 CDS Amir_6328 NC_013093.1 7418682 7419032 R hypothetical protein complement(7418682..7419032) Actinosynnema mirum DSM 43827 8330539 YP_003103977.1 CDS Amir_6329 NC_013093.1 7419187 7419639 D KEGG: acp:A2cp1_1564 protein of unknown function DUF1025; hypothetical protein 7419187..7419639 Actinosynnema mirum DSM 43827 8330540 YP_003103978.1 CDS Amir_6330 NC_013093.1 7420144 7424043 R KEGG: GF17743 gene product from transcript GF17743- RA; glycosyltransferase-like protein complement(7420144..7424043) Actinosynnema mirum DSM 43827 8330541 YP_003103979.1 CDS Amir_6331 NC_013093.1 7424259 7424567 R PFAM: transcription factor WhiB; transcription factor WhiB complement(7424259..7424567) Actinosynnema mirum DSM 43827 8330542 YP_003103980.1 CDS Amir_6332 NC_013093.1 7424894 7425574 D PFAM: peptidase M50; KEGG: ccs:CCNA_03492 transporter; peptidase M50 7424894..7425574 Actinosynnema mirum DSM 43827 8330543 YP_003103981.1 CDS Amir_6333 NC_013093.1 7425600 7426565 D catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); LPPG:FO 2-phospho-L-lactate transferase 7425600..7426565 Actinosynnema mirum DSM 43827 8330544 YP_003103982.1 CDS Amir_6334 NC_013093.1 7426558 7427943 D catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); F420-0--gamma-glutamyl ligase 7426558..7427943 Actinosynnema mirum DSM 43827 8330545 YP_003103983.1 CDS Amir_6335 NC_013093.1 7427946 7428491 D PFAM: NUDIX hydrolase; KEGG: sml:Smlt2194 hypothetical protein; NUDIX hydrolase 7427946..7428491 Actinosynnema mirum DSM 43827 8330546 YP_003103984.1 CDS Amir_6336 NC_013093.1 7428895 7429839 R KEGG: transcriptional regulator, AraC family; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase-like protein complement(7428895..7429839) Actinosynnema mirum DSM 43827 8330547 YP_003103985.1 CDS Amir_6337 NC_013093.1 7429844 7430923 R PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: pca:Pcar_2958 mannose-1-phosphate guanyltransferase; Nucleotidyl transferase complement(7429844..7430923) Actinosynnema mirum DSM 43827 8330548 YP_003103986.1 CDS Amir_6338 NC_013093.1 7431076 7431465 D KEGG: hypothetical protein; hypothetical protein 7431076..7431465 Actinosynnema mirum DSM 43827 8330549 YP_003103987.1 CDS Amir_6339 NC_013093.1 7431664 7432521 R PFAM: glycosyl transferase family 2; KEGG: ppg:PputGB1_2720 glycosyl transferase family protein; family 2 glycosyl transferase complement(7431664..7432521) Actinosynnema mirum DSM 43827 8330550 YP_003103988.1 CDS Amir_6340 NC_013093.1 7433070 7434203 R PFAM: glycosyl transferase group 1; KEGG: pfo:Pfl01_5687 glycosyl transferase, group 1; group 1 glycosyl transferase complement(7433070..7434203) Actinosynnema mirum DSM 43827 8330551 YP_003103989.1 CDS Amir_6341 NC_013093.1 7434377 7435441 R PFAM: glycosyl transferase group 1; KEGG: afw:Anae109_1409 glycosyl transferase group 1; group 1 glycosyl transferase complement(7434377..7435441) Actinosynnema mirum DSM 43827 8330552 YP_003103990.1 CDS Amir_6342 NC_013093.1 7435587 7436489 D PFAM: glycosyl transferase family 2; KEGG: pzu:PHZ_c3342 glycosyl transferase; family 2 glycosyl transferase 7435587..7436489 Actinosynnema mirum DSM 43827 8330553 YP_003103991.1 CDS Amir_6343 NC_013093.1 7436521 7436904 D hypothetical protein 7436521..7436904 Actinosynnema mirum DSM 43827 8330554 YP_003103992.1 CDS Amir_6344 NC_013093.1 7437033 7439501 D PFAM: glycosyl transferase family 2; glycosyl transferase group 1; KEGG: dal:Dalk_0014 glycosyl transferase family 2; family 2 glycosyl transferase 7437033..7439501 Actinosynnema mirum DSM 43827 8330555 YP_003103993.1 CDS Amir_6345 NC_013093.1 7439494 7440588 D PFAM: glycosyl transferase group 1; KEGG: afw:Anae109_1409 glycosyl transferase group 1; group 1 glycosyl transferase 7439494..7440588 Actinosynnema mirum DSM 43827 8330556 YP_003103994.1 CDS Amir_6346 NC_013093.1 7440994 7441884 R KEGG: gme:Gmet_2472 dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase complement(7440994..7441884) Actinosynnema mirum DSM 43827 8330557 YP_003103995.1 CDS Amir_6347 NC_013093.1 7441884 7442876 R TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: dvm:DvMF_0141 dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase complement(7441884..7442876) Actinosynnema mirum DSM 43827 8330558 YP_003103996.1 CDS Amir_6348 NC_013093.1 7443051 7444604 D TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: bat:BAS5047 LytR family transcription antiterminator; cell envelope-related transcriptional attenuator 7443051..7444604 Actinosynnema mirum DSM 43827 8330559 YP_003103997.1 CDS Amir_6349 NC_013093.1 7444683 7445915 D TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: hypothetical protein; cell envelope-related transcriptional attenuator 7444683..7445915 Actinosynnema mirum DSM 43827 8330560 YP_003103998.1 CDS Amir_6350 NC_013093.1 7445926 7446618 D KEGG: rpd:RPD_3317 AMP-dependent synthetase and ligase; hypothetical protein 7445926..7446618 Actinosynnema mirum DSM 43827 8330561 YP_003103999.1 CDS Amir_6351 NC_013093.1 7446711 7447136 R PFAM: DoxX family protein; KEGG: aba:Acid345_2953 DoxX; DoxX family protein complement(7446711..7447136) Actinosynnema mirum DSM 43827 8330562 YP_003104000.1 CDS Amir_6352 NC_013093.1 7447261 7447623 D PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: sme:SM_b20608 transcriptional regulator, ArsR family protein; ArsR family transcriptional regulator 7447261..7447623 Actinosynnema mirum DSM 43827 8330563 YP_003104001.1 CDS Amir_6353 NC_013093.1 7447745 7447957 D hypothetical protein 7447745..7447957 Actinosynnema mirum DSM 43827 8330564 YP_003104002.1 CDS Amir_6354 NC_013093.1 7447954 7448310 D hypothetical protein 7447954..7448310 Actinosynnema mirum DSM 43827 8330565 YP_003104003.1 CDS Amir_6356 NC_013093.1 7448989 7450209 R SMART: helix-turn-helix domain protein; XRE family transcriptional regulator complement(7448989..7450209) Actinosynnema mirum DSM 43827 8330567 YP_003104004.1 CDS Amir_6357 NC_013093.1 7450334 7450567 D hypothetical protein 7450334..7450567 Actinosynnema mirum DSM 43827 8330568 YP_003104005.1 CDS Amir_6358 NC_013093.1 7450681 7451064 R PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: met:M446_0773 GntR family transcriptional regulator; GntR family transcriptional regulator complement(7450681..7451064) Actinosynnema mirum DSM 43827 8330569 YP_003104006.1 CDS Amir_6359 NC_013093.1 7451214 7451645 D hypothetical protein 7451214..7451645 Actinosynnema mirum DSM 43827 8330570 YP_003104007.1 CDS Amir_6360 NC_013093.1 7451658 7451963 D hypothetical protein 7451658..7451963 Actinosynnema mirum DSM 43827 8330571 YP_003104008.1 CDS Amir_6361 NC_013093.1 7452261 7453736 D PFAM: cell divisionFtsK/SpoIIIE; KEGG: pha:PSHAb0091 cell divisionFtsK/SpoIIIE domain-containing protein; cell division protein FtsK/SpoIIIE 7452261..7453736 Actinosynnema mirum DSM 43827 8330572 YP_003104009.1 CDS Amir_6362 NC_013093.1 7453733 7455400 D hypothetical protein 7453733..7455400 Actinosynnema mirum DSM 43827 8330573 YP_003104010.1 CDS Amir_6363 NC_013093.1 7455414 7455593 D hypothetical protein 7455414..7455593 Actinosynnema mirum DSM 43827 8330574 YP_003104011.1 CDS Amir_6364 NC_013093.1 7455630 7456826 D PFAM: integrase family protein; KEGG: bce:BC1272 DNA integration/recombination/invertion protein; integrase family protein 7455630..7456826 Actinosynnema mirum DSM 43827 8330575 YP_003104012.1 CDS Amir_6365 NC_013093.1 7456873 7458351 R KEGG: dps:DP2013 hypothetical protein; hypothetical protein complement(7456873..7458351) Actinosynnema mirum DSM 43827 8330576 YP_003104013.1 CDS Amir_6366 NC_013093.1 7458754 7459917 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: bcb:BCB4264_A5464 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein complement(7458754..7459917) Actinosynnema mirum DSM 43827 8330577 YP_003104014.1 CDS Amir_6367 NC_013093.1 7459952 7460473 R KEGG: predicted protein; K01588 phosphoribosylaminoimidazole carboxylase catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; phosphoribosylaminoimidazole carboxylase, catalytic subunit complement(7459952..7460473) Actinosynnema mirum DSM 43827 8330578 YP_003104015.1 CDS Amir_6368 NC_013093.1 7460470 7461660 R KEGG: hypothetical protein; TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylglycinamide synthetase; phosphoribosylaminoimidazole carboxylase, ATPase subunit complement(7460470..7461660) Actinosynnema mirum DSM 43827 8330579 YP_003104016.1 CDS Amir_6369 NC_013093.1 7461774 7462787 R hypothetical protein complement(7461774..7462787) Actinosynnema mirum DSM 43827 8330580 YP_003104017.1 CDS Amir_6370 NC_013093.1 7462784 7463635 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: shw:Sputw3181_4019 ABC transporter; ABC transporter complement(7462784..7463635) Actinosynnema mirum DSM 43827 8330581 YP_003104018.1 CDS Amir_6371 NC_013093.1 7463632 7464015 R PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sus:Acid_1594 GntR family transcriptional regulator; GntR family transcriptional regulator complement(7463632..7464015) Actinosynnema mirum DSM 43827 8330582 YP_003104019.1 CDS Amir_6372 NC_013093.1 7464280 7465503 R PFAM: hypothetical protein; KEGG: hypothetical protein LOC682657; hypothetical protein complement(7464280..7465503) Actinosynnema mirum DSM 43827 8330583 YP_003104020.1 CDS Amir_6373 NC_013093.1 7465833 7466693 D hypothetical protein 7465833..7466693 Actinosynnema mirum DSM 43827 8330584 YP_003104021.1 CDS Amir_6374 NC_013093.1 7466686 7466871 D PFAM: protein of unknown function DUF397; hypothetical protein 7466686..7466871 Actinosynnema mirum DSM 43827 8330585 YP_003104022.1 CDS Amir_6375 NC_013093.1 7466991 7467410 R hypothetical protein complement(7466991..7467410) Actinosynnema mirum DSM 43827 8330586 YP_003104023.1 CDS Amir_6376 NC_013093.1 7467509 7468306 R KEGG: hypothetical protein; hypothetical protein complement(7467509..7468306) Actinosynnema mirum DSM 43827 8330587 YP_003104024.1 CDS Amir_6377 NC_013093.1 7468403 7471081 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: MUC17; mucin 17, cell surface associated; ECF subfamily RNA polymerase sigma-24 subunit 7468403..7471081 Actinosynnema mirum DSM 43827 8330588 YP_003104025.1 CDS Amir_6378 NC_013093.1 7471237 7471791 D PFAM: GtrA family protein; KEGG: GtrA family protein; GtrA family protein 7471237..7471791 Actinosynnema mirum DSM 43827 8330589 YP_003104026.1 CDS Amir_6379 NC_013093.1 7471863 7472705 R TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: ade:Adeh_1287 histidinol-phosphate phosphatase; histidinol-phosphate phosphatase complement(7471863..7472705) Actinosynnema mirum DSM 43827 8330590 YP_003104027.1 CDS Amir_6380 NC_013093.1 7472738 7473409 D PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: mxa:MXAN_5313 DNA-binding response regulator; winged helix family two component transcriptional regulator 7472738..7473409 Actinosynnema mirum DSM 43827 8330591 YP_003104028.1 CDS Amir_6381 NC_013093.1 7473409 7474683 D PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ade:Adeh_2915 periplasmic sensor signal transduction histidine kinase; histidine kinase 7473409..7474683 Actinosynnema mirum DSM 43827 8330592 YP_003104029.1 CDS Amir_6382 NC_013093.1 7475478 7475918 R KEGG: predicted gene, 100042292; hypothetical protein complement(7475478..7475918) Actinosynnema mirum DSM 43827 8330593 YP_003104030.1 CDS Amir_6383 NC_013093.1 7475915 7478260 R KEGG: Hypothetical protein CBG02561; hypothetical protein complement(7475915..7478260) Actinosynnema mirum DSM 43827 8330594 YP_003104031.1 CDS Amir_6384 NC_013093.1 7478283 7479902 D KEGG: ade:Adeh_1681 PE-PGRS family protein; PE-PGRS family protein 7478283..7479902 Actinosynnema mirum DSM 43827 8330595 YP_003104032.1 CDS Amir_6385 NC_013093.1 7479854 7480162 R hypothetical protein complement(7479854..7480162) Actinosynnema mirum DSM 43827 8330596 YP_003104033.1 CDS Amir_6386 NC_013093.1 7480159 7480650 R hypothetical protein complement(7480159..7480650) Actinosynnema mirum DSM 43827 8330597 YP_003104034.1 CDS Amir_6387 NC_013093.1 7480806 7481735 R PFAM: pyruvate carboxyltransferase; KEGG: rce:RC1_0377 3-hydroxy-3-methylglutaryl-CoA lyase; pyruvate carboxyltransferase complement(7480806..7481735) Actinosynnema mirum DSM 43827 8330598 YP_003104035.1 CDS Amir_6388 NC_013093.1 7482054 7482566 R PFAM: membrane-flanked domain; KEGG: kpe:KPK_2129 hypothetical protein; membrane-flanked domain-containing protein complement(7482054..7482566) Actinosynnema mirum DSM 43827 8330599 YP_003104036.1 CDS Amir_6389 NC_013093.1 7482599 7483360 R TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; KEGG: ade:Adeh_2388 biotin--acetyl-CoA-carboxylase ligase; biotin/acetyl-CoA-carboxylase ligase complement(7482599..7483360) Actinosynnema mirum DSM 43827 8330600 YP_003104037.1 CDS Amir_6390 NC_013093.1 7483647 7485278 D PFAM: carboxyl transferase; KEGG: sus:Acid_1492 carboxyl transferase; carboxyl transferase 7483647..7485278 Actinosynnema mirum DSM 43827 8330601 YP_003104038.1 CDS Amir_6391 NC_013093.1 7485275 7485496 D hypothetical protein 7485275..7485496 Actinosynnema mirum DSM 43827 8330602 YP_003104039.1 CDS Amir_6392 NC_013093.1 7485509 7485913 R hypothetical protein complement(7485509..7485913) Actinosynnema mirum DSM 43827 8330603 YP_003104040.1 CDS Amir_6393 NC_013093.1 7486664 7487284 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 7486664..7487284 Actinosynnema mirum DSM 43827 8330604 YP_003104041.1 CDS Amir_6394 NC_013093.1 7487724 7489064 D PFAM: sodium:dicarboxylate symporter; KEGG: mes:Meso_3163 sodium:dicarboxylate symporter; sodium:dicarboxylate symporter 7487724..7489064 Actinosynnema mirum DSM 43827 8330605 YP_003104042.1 CDS Amir_6395 NC_013093.1 7489135 7489833 R hypothetical protein complement(7489135..7489833) Actinosynnema mirum DSM 43827 8330606 YP_003104043.1 CDS Amir_6396 NC_013093.1 7489992 7491758 D PFAM: carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carbamoyl-phosphate synthetase large chain domain protein; KEGG: biotin carboxylase; K01946 biotin carboxylase; carbamoyl-phosphate synthase L chain ATP- binding 7489992..7491758 Actinosynnema mirum DSM 43827 8330607 YP_003104044.1 CDS Amir_6397 NC_013093.1 7491768 7492154 D PFAM: protein of unknown function DUF1707; hypothetical protein 7491768..7492154 Actinosynnema mirum DSM 43827 8330608 YP_003104045.1 CDS Amir_6398 NC_013093.1 7492151 7493026 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bja:bll1358 hydrolase; HAD superfamily hydrolase 7492151..7493026 Actinosynnema mirum DSM 43827 8330609 YP_003104046.1 CDS Amir_6399 NC_013093.1 7493195 7493788 D hypothetical protein 7493195..7493788 Actinosynnema mirum DSM 43827 8330610 YP_003104047.1 CDS Amir_6400 NC_013093.1 7493880 7494260 D hypothetical protein 7493880..7494260 Actinosynnema mirum DSM 43827 8330611 YP_003104048.1 CDS Amir_6401 NC_013093.1 7494287 7495552 D KEGG: mgm:Mmc1_2179 outer membrane adhesin like proteiin; hypothetical protein 7494287..7495552 Actinosynnema mirum DSM 43827 8330612 YP_003104049.1 CDS Amir_6402 NC_013093.1 7495549 7496355 D hypothetical protein 7495549..7496355 Actinosynnema mirum DSM 43827 8330613 YP_003104050.1 CDS Amir_6403 NC_013093.1 7496622 7497083 R PFAM: AIG2 family protein; KEGG: mpo:Mpop_3184 AIG2 family protein; AIG2 family protein complement(7496622..7497083) Actinosynnema mirum DSM 43827 8330614 YP_003104051.1 CDS Amir_6404 NC_013093.1 7497229 7498632 D catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase 7497229..7498632 Actinosynnema mirum DSM 43827 8330615 YP_003104052.1 CDS Amir_6405 NC_013093.1 7499068 7499745 R PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator complement(7499068..7499745) Actinosynnema mirum DSM 43827 8330616 YP_003104053.1 CDS Amir_6406 NC_013093.1 7499742 7500923 R PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(7499742..7500923) Actinosynnema mirum DSM 43827 8330617 YP_003104054.1 CDS Amir_6407 NC_013093.1 7501129 7502058 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mmr:Mmar10_1823 ABC transporter; ABC transporter 7501129..7502058 Actinosynnema mirum DSM 43827 8330618 YP_003104055.1 CDS Amir_6408 NC_013093.1 7502058 7502921 D KEGG: cak:Caul_1641 hypothetical protein; hypothetical protein 7502058..7502921 Actinosynnema mirum DSM 43827 8330619 YP_003104056.1 CDS Amir_6409 NC_013093.1 7502977 7504491 R TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: azc:AZC_2710 glycerol kinase; glycerol kinase complement(7502977..7504491) Actinosynnema mirum DSM 43827 8330620 YP_003104057.1 CDS Amir_6410 NC_013093.1 7504523 7505263 R PFAM: major intrinsic protein; KEGG: pha:PSHAb0552 glycerol diffusion channel; major intrinsic protein complement(7504523..7505263) Actinosynnema mirum DSM 43827 8330621 YP_003104058.1 CDS Amir_6411 NC_013093.1 7505482 7507221 D PFAM: FAD dependent oxidoreductase; monooxygenase FAD-binding; KEGG: vei:Veis_2018 FAD dependent oxidoreductase; FAD dependent oxidoreductase 7505482..7507221 Actinosynnema mirum DSM 43827 8330622 YP_003104059.1 CDS Amir_6412 NC_013093.1 7507398 7508255 D KEGG: rpa:RPA3963 hypothetical protein; hypothetical protein 7507398..7508255 Actinosynnema mirum DSM 43827 8330623 YP_003104060.1 CDS Amir_6413 NC_013093.1 7508426 7508851 D hypothetical protein 7508426..7508851 Actinosynnema mirum DSM 43827 8330624 YP_003104061.1 CDS Amir_6414 NC_013093.1 7508949 7510220 R KEGG: acr:Acry_1887 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; amidohydrolase complement(7508949..7510220) Actinosynnema mirum DSM 43827 8330625 YP_003104062.1 CDS Amir_6415 NC_013093.1 7510217 7511392 R TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: pla:Plav_2614 amidohydrolase; amidohydrolase complement(7510217..7511392) Actinosynnema mirum DSM 43827 8330626 YP_003104063.1 CDS Amir_6416 NC_013093.1 7511743 7512081 R KEGG: GL26851 gene product from transcript GL26851- RA; hypothetical protein complement(7511743..7512081) Actinosynnema mirum DSM 43827 8330627 YP_003104064.1 CDS Amir_6417 NC_013093.1 7512148 7513134 R TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: rru:Rru_A2478 arginine/ornithine transport system ATPase; LAO/AO transport system ATPase complement(7512148..7513134) Actinosynnema mirum DSM 43827 8330628 YP_003104065.1 CDS Amir_6418 NC_013093.1 7513127 7515316 R MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase complement(7513127..7515316) Actinosynnema mirum DSM 43827 8330629 YP_003104066.1 CDS Amir_6419 NC_013093.1 7515313 7517094 R PFAM: methylmalonyl-CoA mutase; KEGG: rru:Rru_A2480 methylmalonyl-CoA mutase; methylmalonyl-CoA mutase complement(7515313..7517094) Actinosynnema mirum DSM 43827 8330630 YP_003104067.1 CDS Amir_6420 NC_013093.1 7517538 7519355 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: pau:PA14_00875 serine/threonine protein kinase PpkA; serine/threonine protein kinase 7517538..7519355 Actinosynnema mirum DSM 43827 8330631 YP_003104068.1 CDS Amir_6421 NC_013093.1 7519395 7520207 D TIGRFAM: purine nucleotide phosphorylase; inosine guanosine and xanthosine phosphorylase family; PFAM: purine or other phosphorylase family 1; KEGG: scl:sce5862 hypothetical protein; purine nucleotide phosphorylase 7519395..7520207 Actinosynnema mirum DSM 43827 8330632 YP_003104069.1 CDS Amir_6422 NC_013093.1 7520204 7521832 D PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: scl:sce4837 phosphoglucomutase/phosphomannomutase; phosphomannomutase 7520204..7521832 Actinosynnema mirum DSM 43827 8330633 YP_003104070.1 CDS Amir_6423 NC_013093.1 7521867 7522190 R hypothetical protein complement(7521867..7522190) Actinosynnema mirum DSM 43827 8330634 YP_003104071.1 CDS Amir_6424 NC_013093.1 7522246 7522575 R KEGG: acp:A2cp1_4175 general secretory system II protein E domain protein; hypothetical protein complement(7522246..7522575) Actinosynnema mirum DSM 43827 8330635 YP_003104072.1 CDS Amir_6425 NC_013093.1 7522875 7523270 R PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; KEGG: mag:amb3964 transcriptional regulator; MerR family transcriptional regulator complement(7522875..7523270) Actinosynnema mirum DSM 43827 8330636 YP_003104073.1 CDS Amir_6426 NC_013093.1 7523386 7523769 R PFAM: filamentation induced by cAMP protein Fic; KEGG: acp:A2cp1_3061 death-on-curing family protein; filamentation induced by cAMP protein Fic complement(7523386..7523769) Actinosynnema mirum DSM 43827 8330637 YP_003104074.1 CDS Amir_6427 NC_013093.1 7523810 7524010 R PFAM: CopG domain protein DNA-binding domain protein; KEGG: tgr:Tgr7_2434 CopG domain protein DNA-binding domain protein; CopG domain-containing protein DNA-binding domain-containing protein complement(7523810..7524010) Actinosynnema mirum DSM 43827 8330638 YP_003104075.1 CDS Amir_6428 NC_013093.1 7524033 7524686 D PFAM: regulatory protein TetR; KEGG: pla:Plav_2655 TetR family transcriptional regulator; TetR family transcriptional regulator 7524033..7524686 Actinosynnema mirum DSM 43827 8330639 YP_003104076.1 CDS Amir_6429 NC_013093.1 7525128 7525751 R TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: rde:RD1_3976 uracil phosphoribosyltransferase; uracil phosphoribosyltransferase complement(7525128..7525751) Actinosynnema mirum DSM 43827 8330640 YP_003104077.1 CDS Amir_6430 NC_013093.1 7525948 7528944 D PFAM: pentapeptide repeat protein; KEGG: scl:sce3623 hypothetical protein; pentapeptide repeat-containing protein 7525948..7528944 Actinosynnema mirum DSM 43827 8330641 YP_003104078.1 CDS Amir_6431 NC_013093.1 7529075 7534375 D PFAM: hypothetical protein; pentapeptide repeat protein; SMART: hypothetical protein; KEGG: scl:sce3623 hypothetical protein; hypothetical protein 7529075..7534375 Actinosynnema mirum DSM 43827 8330642 YP_003104079.1 CDS Amir_6432 NC_013093.1 7534379 7535362 D PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: hypothetical protein; oxidoreductase domain-containing protein 7534379..7535362 Actinosynnema mirum DSM 43827 8330643 YP_003104080.1 CDS Amir_6433 NC_013093.1 7535359 7535610 R hypothetical protein complement(7535359..7535610) Actinosynnema mirum DSM 43827 8330644 YP_003104081.1 CDS Amir_6434 NC_013093.1 7535679 7536518 D SMART: helix-turn-helix domain protein; KEGG: met:M446_4768 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 7535679..7536518 Actinosynnema mirum DSM 43827 8330645 YP_003104082.1 CDS Amir_6435 NC_013093.1 7536532 7536705 D PFAM: protein of unknown function DUF397; hypothetical protein 7536532..7536705 Actinosynnema mirum DSM 43827 8330646 YP_003104083.1 CDS Amir_6436 NC_013093.1 7536751 7537407 D PFAM: protein of unknown function DUF1707; KEGG: pha:PSHAa0324 hypothetical protein; hypothetical protein 7536751..7537407 Actinosynnema mirum DSM 43827 8330647 YP_003104084.1 CDS Amir_6437 NC_013093.1 7537472 7539619 R PFAM: NB-ARC domain protein; KEGG: scl:sce6858 hypothetical protein; NB-ARC domain-containing protein complement(7537472..7539619) Actinosynnema mirum DSM 43827 8330648 YP_003104085.1 CDS Amir_6438 NC_013093.1 7539624 7540136 R hypothetical protein complement(7539624..7540136) Actinosynnema mirum DSM 43827 8330649 YP_003104086.1 CDS Amir_6439 NC_013093.1 7540111 7540347 R hypothetical protein complement(7540111..7540347) Actinosynnema mirum DSM 43827 8330650 YP_003104087.1 CDS Amir_6440 NC_013093.1 7540530 7540958 R hypothetical protein complement(7540530..7540958) Actinosynnema mirum DSM 43827 8330651 YP_003104088.1 CDS Amir_6441 NC_013093.1 7541203 7541526 D hypothetical protein 7541203..7541526 Actinosynnema mirum DSM 43827 8330652 YP_003104089.1 CDS Amir_6442 NC_013093.1 7541532 7542710 D PFAM: NLP/P60 protein; KEGG: bpt:Bpet2252 hypothetical protein; NLP/P60 protein 7541532..7542710 Actinosynnema mirum DSM 43827 8330653 YP_003104090.1 CDS Amir_6443 NC_013093.1 7542715 7543089 D hypothetical protein 7542715..7543089 Actinosynnema mirum DSM 43827 8330654 YP_003104091.1 CDS Amir_6444 NC_013093.1 7543086 7545728 D KEGG: mgm:Mmc1_2162 hypothetical protein; Chromosome segregation ATPase-like protein 7543086..7545728 Actinosynnema mirum DSM 43827 8330655 YP_003104092.1 CDS Amir_6445 NC_013093.1 7545811 7547025 D hypothetical protein 7545811..7547025 Actinosynnema mirum DSM 43827 8330656 YP_003104093.1 CDS Amir_6446 NC_013093.1 7547102 7548172 R KEGG: afw:Anae109_0100 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; adenosine deaminase complement(7547102..7548172) Actinosynnema mirum DSM 43827 8330657 YP_003104094.1 CDS Amir_6447 NC_013093.1 7548446 7549672 D KEGG: CG33251; hypothetical protein 7548446..7549672 Actinosynnema mirum DSM 43827 8330658 YP_003104095.1 CDS Amir_6448 NC_013093.1 7550003 7550587 D hypothetical protein 7550003..7550587 Actinosynnema mirum DSM 43827 8330659 YP_003104096.1 CDS deoA NC_013093.1 7550646 7551920 R Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase complement(7550646..7551920) Actinosynnema mirum DSM 43827 8330660 YP_003104097.1 CDS Amir_6450 NC_013093.1 7551917 7552360 R PFAM: CMP/dCMP deaminase zinc-binding; KEGG: nar:Saro_0145 cytidine deaminase; zinc-binding CMP/dCMP deaminase complement(7551917..7552360) Actinosynnema mirum DSM 43827 8330661 YP_003104098.1 CDS Amir_6451 NC_013093.1 7552353 7553618 R PFAM: inner-membrane translocator; KEGG: bcz:BCZK3548 ABC transporter, permease; inner-membrane translocator complement(7552353..7553618) Actinosynnema mirum DSM 43827 8330662 YP_003104099.1 CDS Amir_6452 NC_013093.1 7553615 7554688 R PFAM: inner-membrane translocator; KEGG: scl:sce7757 ABC transporter permease; inner-membrane translocator complement(7553615..7554688) Actinosynnema mirum DSM 43827 8330663 YP_003104100.1 CDS Amir_6453 NC_013093.1 7554688 7556232 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce7755 sugar ABC transporter, ATP- binding protein; ABC transporter complement(7554688..7556232) Actinosynnema mirum DSM 43827 8330664 YP_003104101.1 CDS Amir_6454 NC_013093.1 7556303 7557451 R PFAM: basic membrane lipoprotein; KEGG: smd:Smed_3416 basic membrane lipoprotein; basic membrane lipoprotein complement(7556303..7557451) Actinosynnema mirum DSM 43827 8330665 YP_003104102.1 CDS Amir_6455 NC_013093.1 7557993 7558517 D KEGG: avhD4; conjugative coupling protein; K03205 type IV secretion system protein VirD4; hypothetical protein 7557993..7558517 Actinosynnema mirum DSM 43827 8330666 YP_003104103.1 CDS Amir_6456 NC_013093.1 7558574 7560247 D KEGG: mucin-associated surface protein (MASP); hypothetical protein 7558574..7560247 Actinosynnema mirum DSM 43827 8330667 YP_003104104.1 CDS Amir_6457 NC_013093.1 7560273 7565210 R KEGG: eln1; tropoelastin 1; hypothetical protein complement(7560273..7565210) Actinosynnema mirum DSM 43827 8330668 YP_003104105.1 CDS Amir_6458 NC_013093.1 7565242 7593831 D KEGG: Muc19; mucin 19; hypothetical protein 7565242..7593831 Actinosynnema mirum DSM 43827 8330669 YP_003104106.1 CDS Amir_6459 NC_013093.1 7593828 7595096 D hypothetical protein 7593828..7595096 Actinosynnema mirum DSM 43827 8330670 YP_003104107.1 CDS Amir_6460 NC_013093.1 7595549 7595839 R KEGG: GK19428 gene product from transcript GK19428- RA; hypothetical protein complement(7595549..7595839) Actinosynnema mirum DSM 43827 8330671 YP_003104108.1 CDS Amir_6461 NC_013093.1 7595856 7599962 D KEGG: ank:AnaeK_3854 tetratricopeptide TPR_2 repeat protein; hypothetical protein 7595856..7599962 Actinosynnema mirum DSM 43827 8330672 YP_003104109.1 CDS Amir_6462 NC_013093.1 7600183 7600605 D TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: jan:Jann_3968 succinate dehydrogenase subunit C; succinate dehydrogenase, cytochrome b556 subunit 7600183..7600605 Actinosynnema mirum DSM 43827 8330673 YP_003104110.1 CDS Amir_6463 NC_013093.1 7600608 7601024 D KEGG: eta:ETA_23070 succinate dehydrogenase hydrophobic membrane anchor protein; Succinate dehydrogenase hydrophobic anchor subunit-like protein 7600608..7601024 Actinosynnema mirum DSM 43827 8330674 YP_003104111.1 CDS sdhA NC_013093.1 7601047 7602798 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 7601047..7602798 Actinosynnema mirum DSM 43827 8330675 YP_003104112.1 CDS sdhB NC_013093.1 7602798 7603580 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 7602798..7603580 Actinosynnema mirum DSM 43827 8330676 YP_003104113.1 CDS Amir_6466 NC_013093.1 7603854 7605863 R PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: rpc:RPC_4073 serine-type D-Ala-D-Ala carboxypeptidase; Serine-type D-Ala-D-Ala carboxypeptidase complement(7603854..7605863) Actinosynnema mirum DSM 43827 8330677 YP_003104114.1 CDS Amir_6467 NC_013093.1 7605963 7606190 D hypothetical protein 7605963..7606190 Actinosynnema mirum DSM 43827 8330678 YP_003104115.1 CDS Amir_6468 NC_013093.1 7606219 7606566 D hypothetical protein 7606219..7606566 Actinosynnema mirum DSM 43827 8330679 YP_003104116.1 CDS Amir_6469 NC_013093.1 7606724 7607743 R TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: ypb:YPTS_4040 ribonuclease; ribonuclease complement(7606724..7607743) Actinosynnema mirum DSM 43827 8330680 YP_003104117.1 CDS Amir_6470 NC_013093.1 7607878 7608897 R KEGG: aha:AHA_3183 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; tryptophanyl-tRNA synthetase complement(7607878..7608897) Actinosynnema mirum DSM 43827 8330681 YP_003104118.1 CDS Amir_6471 NC_013093.1 7608919 7609221 R KEGG: hypothetical protein; hypothetical protein complement(7608919..7609221) Actinosynnema mirum DSM 43827 8330682 YP_003104119.1 CDS fbiC NC_013093.1 7609384 7611900 R 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; FO synthase complement(7609384..7611900) Actinosynnema mirum DSM 43827 8330683 YP_003104120.1 CDS Amir_6473 NC_013093.1 7612047 7612325 R PFAM: protein of unknown function DUF86; KEGG: azo:azo0145 hypothetical protein; hypothetical protein complement(7612047..7612325) Actinosynnema mirum DSM 43827 8330684 YP_003104121.1 CDS Amir_6474 NC_013093.1 7612315 7612623 R PFAM: DNA polymerase beta domain protein region; KEGG: aba:Acid345_1968 nucleotidyltransferase; DNA polymerase beta domain-containing protein complement(7612315..7612623) Actinosynnema mirum DSM 43827 8330685 YP_003104122.1 CDS Amir_6475 NC_013093.1 7612665 7613459 R KEGG: nma:NMA0348 nuclease; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: endonuclease/exonuclease/phosphatase; exodeoxyribonuclease III Xth complement(7612665..7613459) Actinosynnema mirum DSM 43827 8330686 YP_003104123.1 CDS Amir_6476 NC_013093.1 7613469 7613684 R hypothetical protein complement(7613469..7613684) Actinosynnema mirum DSM 43827 8330687 YP_003104124.1 CDS Amir_6477 NC_013093.1 7613740 7614066 R hypothetical protein complement(7613740..7614066) Actinosynnema mirum DSM 43827 8330688 YP_003104125.1 CDS Amir_6478 NC_013093.1 7614279 7615499 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(7614279..7615499) Actinosynnema mirum DSM 43827 8330689 YP_003104126.1 CDS Amir_6479 NC_013093.1 7615639 7616445 D PFAM: membrane-bound metal-dependent hydrolase; KEGG: mag:amb4172 membrane-bound metal-dependent hydrolase; membrane-bound metal-dependent hydrolase 7615639..7616445 Actinosynnema mirum DSM 43827 8330690 YP_003104127.1 CDS Amir_6480 NC_013093.1 7616546 7617025 D hypothetical protein 7616546..7617025 Actinosynnema mirum DSM 43827 8330691 YP_003104128.1 CDS Amir_6481 NC_013093.1 7617236 7618387 D PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: rle:pRL110201 chaperone; heat shock protein DnaJ domain-containing protein 7617236..7618387 Actinosynnema mirum DSM 43827 8330693 YP_003104129.1 CDS Amir_6482 NC_013093.1 7618413 7620188 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_2255 serine/threonine protein kinase; serine/threonine protein kinase 7618413..7620188 Actinosynnema mirum DSM 43827 8330694 YP_003104130.1 CDS Amir_6483 NC_013093.1 7620268 7620465 D hypothetical protein 7620268..7620465 Actinosynnema mirum DSM 43827 8330695 YP_003104131.1 CDS Amir_6484 NC_013093.1 7620462 7620893 D hypothetical protein 7620462..7620893 Actinosynnema mirum DSM 43827 8330696 YP_003104132.1 CDS Amir_6485 NC_013093.1 7621198 7621983 D KEGG: reu:Reut_A1068 ABC transporter permease protein; ABC transporter permease 7621198..7621983 Actinosynnema mirum DSM 43827 8330697 YP_003104133.1 CDS Amir_6486 NC_013093.1 7621976 7622773 D PFAM: protein of unknown function DUF990; KEGG: aav:Aave_2071 protein of unknown function DUF990; hypothetical protein 7621976..7622773 Actinosynnema mirum DSM 43827 8330698 YP_003104134.1 CDS Amir_6487 NC_013093.1 7622770 7623723 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: scl:sce6750 ABC transporter, ATP-binding protein; ABC transporter 7622770..7623723 Actinosynnema mirum DSM 43827 8330699 YP_003104135.1 CDS Amir_6488 NC_013093.1 7623763 7624158 D hypothetical protein 7623763..7624158 Actinosynnema mirum DSM 43827 8330700 YP_003104136.1 CDS Amir_6489 NC_013093.1 7624265 7624456 D PFAM: Domain of unknown function DUF1918; hypothetical protein 7624265..7624456 Actinosynnema mirum DSM 43827 8330701 YP_003104137.1 CDS Amir_6490 NC_013093.1 7624453 7625184 R PFAM: regulatory protein TetR; KEGG: mes:Meso_0701 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(7624453..7625184) Actinosynnema mirum DSM 43827 8330702 YP_003104138.1 CDS Amir_6491 NC_013093.1 7625682 7626476 R PFAM: inositol monophosphatase; KEGG: mes:Meso_2748 histidinol-phosphate phosphatase; inositol monophosphatase complement(7625682..7626476) Actinosynnema mirum DSM 43827 8330703 YP_003104139.1 CDS Amir_6492 NC_013093.1 7626582 7627571 R catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase complement(7626582..7627571) Actinosynnema mirum DSM 43827 8330704 YP_003104140.1 CDS Amir_6493 NC_013093.1 7627731 7628345 D PFAM: pentapeptide repeat protein; KEGG: bca:BCE_1946 hypothetical protein; pentapeptide repeat-containing protein 7627731..7628345 Actinosynnema mirum DSM 43827 8330705 YP_003104141.1 CDS Amir_6494 NC_013093.1 7628404 7632021 R KEGG: mgm:Mmc1_1473 conserved hypothetical protein, conserved; hypothetical protein complement(7628404..7632021) Actinosynnema mirum DSM 43827 8330706 YP_003104142.1 CDS Amir_6495 NC_013093.1 7632103 7633626 R KEGG: mag:amb0236 hypothetical protein; hypothetical protein complement(7632103..7633626) Actinosynnema mirum DSM 43827 8330707 YP_003104143.1 CDS Amir_6496 NC_013093.1 7633623 7634093 R hypothetical protein complement(7633623..7634093) Actinosynnema mirum DSM 43827 8330708 YP_003104144.1 CDS Amir_6497 NC_013093.1 7634285 7635277 D PFAM: protein of unknown function DUF606; KEGG: pmr:PMI1526 hypothetical protein; hypothetical protein 7634285..7635277 Actinosynnema mirum DSM 43827 8330709 YP_003104145.1 CDS Amir_6498 NC_013093.1 7635285 7636151 D PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: pca:Pcar_2461 methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; methenyltetrahydrofolate cyclohydrolase 7635285..7636151 Actinosynnema mirum DSM 43827 8330710 YP_003104146.1 CDS Amir_6499 NC_013093.1 7636172 7636471 D hypothetical protein 7636172..7636471 Actinosynnema mirum DSM 43827 8330711 YP_003104147.1 CDS Amir_6500 NC_013093.1 7636708 7636863 R hypothetical protein complement(7636708..7636863) Actinosynnema mirum DSM 43827 8330712 YP_003104148.1 CDS Amir_6502 NC_013093.1 7637872 7638678 D KEGG: hypothetical LOC792361; hypothetical protein 7637872..7638678 Actinosynnema mirum DSM 43827 8330714 YP_003104149.1 CDS purH NC_013093.1 7638927 7640498 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(7638927..7640498) Actinosynnema mirum DSM 43827 8330715 YP_003104150.1 CDS purN NC_013093.1 7640495 7641130 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(7640495..7641130) Actinosynnema mirum DSM 43827 8330716 YP_003104151.1 CDS Amir_6505 NC_013093.1 7641281 7643146 R KEGG: hypothetical protein LOC690456; ATPase AAA complement(7641281..7643146) Actinosynnema mirum DSM 43827 8330717 YP_003104152.1 CDS Amir_6506 NC_013093.1 7643262 7643963 R KEGG: similar to AGAP004367-PA; hypothetical protein complement(7643262..7643963) Actinosynnema mirum DSM 43827 8330718 YP_003104153.1 CDS Amir_6507 NC_013093.1 7644147 7645037 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(7644147..7645037) Actinosynnema mirum DSM 43827 8330719 YP_003104154.1 CDS sucC NC_013093.1 7645043 7646212 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(7645043..7646212) Actinosynnema mirum DSM 43827 8330720 YP_003104155.1 CDS Amir_6509 NC_013093.1 7646449 7648011 R KEGG: mpo:Mpop_4712 hypothetical protein; hypothetical protein complement(7646449..7648011) Actinosynnema mirum DSM 43827 8330721 YP_003104156.1 CDS Amir_6510 NC_013093.1 7648571 7649452 R KEGG: bpm:BURPS1710b_2554 hypothetical protein; hypothetical protein complement(7648571..7649452) Actinosynnema mirum DSM 43827 8330722 YP_003104157.1 CDS Amir_6511 NC_013093.1 7650110 7650784 D PFAM: peptidase M23; KEGG: peptidase M23B; peptidase M23 7650110..7650784 Actinosynnema mirum DSM 43827 8330723 YP_003104158.1 CDS Amir_6512 NC_013093.1 7650759 7651124 R hypothetical protein complement(7650759..7651124) Actinosynnema mirum DSM 43827 8330724 YP_003104159.1 CDS Amir_6513 NC_013093.1 7651764 7654109 R TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase; ATP-dependent DNA helicase PcrA complement(7651764..7654109) Actinosynnema mirum DSM 43827 8330725 YP_003104160.1 CDS Amir_6514 NC_013093.1 7654346 7654636 D TIGRFAM: chorismate mutase; KEGG: cha:CHAB381_1299 chorismate mutase/prephenate dehydratase; chorismate mutase 7654346..7654636 Actinosynnema mirum DSM 43827 8330726 YP_003104161.1 CDS Amir_6515 NC_013093.1 7654778 7655842 R PFAM: histone deacetylase superfamily; KEGG: HDA08; HDA08 (histone deacetylase 8); histone deacetylase; histone deacetylase superfamily complement(7654778..7655842) Actinosynnema mirum DSM 43827 8330727 YP_003104162.1 CDS Amir_6516 NC_013093.1 7655913 7656230 D KEGG: gbm:Gbem_3934 protein of unknown function DUF6 transmembrane; hypothetical protein 7655913..7656230 Actinosynnema mirum DSM 43827 8330728 YP_003104163.1 CDS Amir_6517 NC_013093.1 7656333 7657271 D KEGG: Taf4a; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor; K03129 transcription initiation factor TFIID subunit D3; hypothetical protein 7656333..7657271 Actinosynnema mirum DSM 43827 8330729 YP_003104164.1 CDS Amir_6518 NC_013093.1 7657458 7658285 D hypothetical protein 7657458..7658285 Actinosynnema mirum DSM 43827 8330730 YP_003104165.1 CDS Amir_6519 NC_013093.1 7658447 7659370 D KEGG: GH10507 gene product from transcript GH10507- RA; hypothetical protein 7658447..7659370 Actinosynnema mirum DSM 43827 8330731 YP_003104166.1 CDS Amir_6520 NC_013093.1 7659642 7661042 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_4017 serine/threonine protein kinase; serine/threonine protein kinase 7659642..7661042 Actinosynnema mirum DSM 43827 8330732 YP_003104167.1 CDS Amir_6521 NC_013093.1 7661187 7662848 D PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mxa:MXAN_4017 serine/threonine protein kinase; serine/threonine protein kinase 7661187..7662848 Actinosynnema mirum DSM 43827 8330733 YP_003104168.1 CDS Amir_6522 NC_013093.1 7662882 7663784 R PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aav:Aave_0303 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(7662882..7663784) Actinosynnema mirum DSM 43827 8330734 YP_003104169.1 CDS Amir_6523 NC_013093.1 7663866 7664807 D PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: hypothetical protein; hypothetical protein 7663866..7664807 Actinosynnema mirum DSM 43827 8330735 YP_003104170.1 CDS Amir_6524 NC_013093.1 7664979 7665389 D PFAM: sporulation and cell division protein SsgA; sporulation and cell division protein SsgA 7664979..7665389 Actinosynnema mirum DSM 43827 8330736 YP_003104171.1 CDS Amir_6525 NC_013093.1 7665431 7666081 R PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: eba:ebA6278 nitrate/nitrite response regulator; LuxR family transcriptional regulator complement(7665431..7666081) Actinosynnema mirum DSM 43827 8330737 YP_003104172.1 CDS Amir_6526 NC_013093.1 7666078 7667412 R PFAM: PspC domain protein; ATP-binding region ATPase domain protein; KEGG: sus:Acid_2189 histidine kinase; signal transduction histidine kinase complement(7666078..7667412) Actinosynnema mirum DSM 43827 8330738 YP_003104173.1 CDS Amir_6527 NC_013093.1 7667432 7668685 D PFAM: PspC domain protein; KEGG: aba:Acid345_1324 phage shock protein C, PspC; phage shock protein PspC 7667432..7668685 Actinosynnema mirum DSM 43827 8330739 YP_003104174.1 CDS Amir_6528 NC_013093.1 7668678 7668881 D hypothetical protein 7668678..7668881 Actinosynnema mirum DSM 43827 8330740 YP_003104175.1 CDS guaA NC_013093.1 7669002 7670561 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(7669002..7670561) Actinosynnema mirum DSM 43827 8330741 YP_003104176.1 CDS Amir_6530 NC_013093.1 7670661 7671377 D PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce4958 hypothetical protein; aminoglycoside phosphotransferase 7670661..7671377 Actinosynnema mirum DSM 43827 8330742 YP_003104177.1 CDS Amir_6531 NC_013093.1 7671412 7672857 D PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_2844 succinate-semialdehyde dehydrogenase; aldehyde dehydrogenase 7671412..7672857 Actinosynnema mirum DSM 43827 8330743 YP_003104178.1 CDS Amir_6532 NC_013093.1 7673298 7674986 R PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: scl:sce0787 hypothetical protein; glucose-methanol-choline oxidoreductase complement(7673298..7674986) Actinosynnema mirum DSM 43827 8330744 YP_003104179.1 CDS Amir_6533 NC_013093.1 7675150 7675356 R hypothetical protein complement(7675150..7675356) Actinosynnema mirum DSM 43827 8330745 YP_003104180.1 CDS Amir_6534 NC_013093.1 7675514 7676647 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase complement(7675514..7676647) Actinosynnema mirum DSM 43827 8330746 YP_003104181.1 CDS Amir_6535 NC_013093.1 7676679 7678190 R KEGG: sfu:Sfum_2122 inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; SMART: CBS domain containing protein; inosine-5'-monophosphate dehydrogenase complement(7676679..7678190) Actinosynnema mirum DSM 43827 8330747 YP_003104182.1 CDS Amir_6536 NC_013093.1 7678314 7678709 D hypothetical protein 7678314..7678709 Actinosynnema mirum DSM 43827 8330748 YP_003104183.1 CDS Amir_6537 NC_013093.1 7678850 7679770 R KEGG: similar to mucin 7, salivary; hypothetical protein complement(7678850..7679770) Actinosynnema mirum DSM 43827 8330749 YP_003104184.1 CDS Amir_6538 NC_013093.1 7679771 7680343 R TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: mno:Mnod_5360 RNA polymerase, sigma-24 subunit, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit complement(7679771..7680343) Actinosynnema mirum DSM 43827 8330750 YP_003104185.1 CDS Amir_6539 NC_013093.1 7681488 7682084 R PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; KEGG: smt:Smal_2340 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator complement(7681488..7682084) Actinosynnema mirum DSM 43827 8330751 YP_003104186.1 CDS Amir_6540 NC_013093.1 7682165 7683715 R KEGG: hypothetical protein; hypothetical protein complement(7682165..7683715) Actinosynnema mirum DSM 43827 8330752 YP_003104187.1 CDS Amir_6541 NC_013093.1 7683992 7684921 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: mxa:MXAN_0904 B12 binding domain/transcriptional regulator, MerR family; MerR family transcriptional regulator complement(7683992..7684921) Actinosynnema mirum DSM 43827 8330753 YP_003104188.1 CDS Amir_6542 NC_013093.1 7685149 7685484 D PFAM: transcription factor WhiB; transcription factor WhiB 7685149..7685484 Actinosynnema mirum DSM 43827 8330754 YP_003104189.1 CDS Amir_6543 NC_013093.1 7685657 7687282 R TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: sus:Acid_6747 chaperonin GroEL; chaperonin GroEL complement(7685657..7687282) Actinosynnema mirum DSM 43827 8330755 YP_003104190.1 CDS Amir_6544 NC_013093.1 7687367 7687660 R PFAM: chaperonin Cpn10; KEGG: bcu:BCAH820_0292 chaperonin, 10 kDa; chaperonin Cpn10 complement(7687367..7687660) Actinosynnema mirum DSM 43827 8330756 YP_003104191.1 CDS Amir_6545 NC_013093.1 7688022 7688855 R hypothetical protein complement(7688022..7688855) Actinosynnema mirum DSM 43827 8330757 YP_003104192.1 CDS Amir_6546 NC_013093.1 7689012 7690064 R KEGG: afw:Anae109_3813 metalloendopeptidase glycoprotease family; TIGRFAM: metalloendopeptidase, glycoprotease family; PFAM: peptidase M22 glycoprotease; metalloendopeptidase, glycoprotease family complement(7689012..7690064) Actinosynnema mirum DSM 43827 8330758 YP_003104193.1 CDS Amir_6547 NC_013093.1 7690057 7690515 R TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: smt:Smal_0531 ribosomal-protein-alanine acetyltransferase; ribosomal-protein-alanine acetyltransferase complement(7690057..7690515) Actinosynnema mirum DSM 43827 8330759 YP_003104194.1 CDS Amir_6548 NC_013093.1 7690512 7691210 R PFAM: peptidase M22 glycoprotease; KEGG: pzu:PHZ_c3457 metal-dependent protease (with possible chaperone activity); peptidase M22 glycoprotease complement(7690512..7691210) Actinosynnema mirum DSM 43827 8330760 YP_003104195.1 CDS Amir_6549 NC_013093.1 7691276 7691662 D PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: rpa:RPA4825 MerR family transcriptional regulator; MerR family transcriptional regulator 7691276..7691662 Actinosynnema mirum DSM 43827 8330761 YP_003104196.1 CDS Amir_6550 NC_013093.1 7691650 7691955 D PFAM: Thioredoxin domain; KEGG: bcy:Bcer98_3221 thioredoxin; thioredoxin domain-containing protein 7691650..7691955 Actinosynnema mirum DSM 43827 8330762 YP_003104197.1 CDS Amir_6551 NC_013093.1 7691986 7693338 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 7691986..7693338 Actinosynnema mirum DSM 43827 8330763 YP_003104198.1 CDS Amir_6553 NC_013093.1 7694043 7694567 R hypothetical protein complement(7694043..7694567) Actinosynnema mirum DSM 43827 8330765 YP_003104199.1 CDS Amir_6554 NC_013093.1 7694629 7695108 R PFAM: protein of unknown function UPF0079; KEGG: jan:Jann_4062 hypothetical protein; hypothetical protein complement(7694629..7695108) Actinosynnema mirum DSM 43827 8330766 YP_003104200.1 CDS Amir_6555 NC_013093.1 7695108 7696208 R PFAM: alpha/beta hydrolase fold; KEGG: scl:sce8687 hypothetical protein; alpha/beta hydrolase fold protein complement(7695108..7696208) Actinosynnema mirum DSM 43827 8330767 YP_003104201.1 CDS Amir_6556 NC_013093.1 7696205 7697371 R KEGG: dol:Dole_0057 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein; alanine racemase complement(7696205..7697371) Actinosynnema mirum DSM 43827 8330768 YP_003104202.1 CDS Amir_6557 NC_013093.1 7697368 7698765 R TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF- family domain protein; KEGG: swi:Swit_4659 carbohydrate kinase, YjeF related protein; carbohydrate kinase complement(7697368..7698765) Actinosynnema mirum DSM 43827 8330769 YP_003104203.1 CDS Amir_6558 NC_013093.1 7698890 7700752 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(7698890..7700752) Actinosynnema mirum DSM 43827 8330770 YP_003104204.1 CDS Amir_6559 NC_013093.1 7700887 7701699 D KEGG: scl:sce1807 hypothetical protein; dienelactone hydrolase-like protein 7700887..7701699 Actinosynnema mirum DSM 43827 8330771 YP_003104205.1 CDS Amir_6560 NC_013093.1 7701823 7702305 R KEGG: hypothetical protein; hypothetical protein complement(7701823..7702305) Actinosynnema mirum DSM 43827 8330772 YP_003104206.1 CDS Amir_6561 NC_013093.1 7702302 7705190 R KEGG: hypothetical protein; hypothetical protein complement(7702302..7705190) Actinosynnema mirum DSM 43827 8330773 YP_003104207.1 CDS Amir_6562 NC_013093.1 7705187 7705480 R hypothetical protein complement(7705187..7705480) Actinosynnema mirum DSM 43827 8330774 YP_003104208.1 CDS Amir_6563 NC_013093.1 7705799 7707133 R TIGRFAM: phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: pca:Pcar_1001 phosphohexomutase; phosphoglucosamine mutase complement(7705799..7707133) Actinosynnema mirum DSM 43827 8330775 YP_003104209.1 CDS Amir_6564 NC_013093.1 7707252 7707902 R PFAM: ribosomal protein S9; KEGG: bha:BH0169 30S ribosomal protein S9; 30S ribosomal protein S9 complement(7707252..7707902) Actinosynnema mirum DSM 43827 8330776 YP_003104210.1 CDS rplM NC_013093.1 7707899 7708342 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(7707899..7708342) Actinosynnema mirum DSM 43827 8330777 YP_003104211.1 CDS Amir_6566 NC_013093.1 7708647 7708937 R PFAM: protein of unknown function DUF909; KEGG: hypothetical protein; hypothetical protein complement(7708647..7708937) Actinosynnema mirum DSM 43827 8330778 YP_003104212.1 CDS Amir_6567 NC_013093.1 7709021 7709338 R PFAM: protein of unknown function DUF909; hypothetical protein complement(7709021..7709338) Actinosynnema mirum DSM 43827 8330779 YP_003104213.1 CDS Amir_6568 NC_013093.1 7709487 7709903 R KEGG: bpl:BURPS1106A_A2538 chemotaxis histidine kinase/response regulator; chemotaxis histidine kinase/response regulator complement(7709487..7709903) Actinosynnema mirum DSM 43827 8330780 YP_003104214.1 CDS Amir_6569 NC_013093.1 7709920 7711851 R PFAM: Heat shock protein 70; KEGG: mag:amb3024 chaperone protein HscA; Heat shock protein 70 complement(7709920..7711851) Actinosynnema mirum DSM 43827 8330781 YP_003104215.1 CDS Amir_6570 NC_013093.1 7712435 7713076 D hypothetical protein 7712435..7713076 Actinosynnema mirum DSM 43827 8330782 YP_003104216.1 CDS Amir_6571 NC_013093.1 7713178 7717179 R PFAM: cell divisionFtsK/SpoIIIE; KEGG: bcz:BCZK1985 FtsK/SpoIIIE family protein; cell division protein FtsK/SpoIIIE complement(7713178..7717179) Actinosynnema mirum DSM 43827 8330783 YP_003104217.1 CDS Amir_6572 NC_013093.1 7717462 7718856 D TIGRFAM: secretion protein snm4; PFAM: protein of unknown function DUF571; KEGG: hypothetical protein; secretion protein snm4 7717462..7718856 Actinosynnema mirum DSM 43827 8330784 YP_003104218.1 CDS Amir_6573 NC_013093.1 7718868 7720346 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: bca:BCE_2410 alkaline serine protease; peptidase S8/S53 subtilisin kexin sedolisin 7718868..7720346 Actinosynnema mirum DSM 43827 8330785 YP_003104219.1 CDS Amir_6574 NC_013093.1 7720549 7721688 R KEGG: predicted gene, 100041170; hypothetical protein complement(7720549..7721688) Actinosynnema mirum DSM 43827 8330786 YP_003104220.1 CDS Amir_6575 NC_013093.1 7721703 7722047 R hypothetical protein complement(7721703..7722047) Actinosynnema mirum DSM 43827 8330787 YP_003104221.1 CDS Amir_6576 NC_013093.1 7722436 7724058 R PFAM: protein of unknown function DUF690; hypothetical protein complement(7722436..7724058) Actinosynnema mirum DSM 43827 8330788 YP_003104222.1 CDS Amir_6577 NC_013093.1 7724292 7725620 D KEGG: GK21128 gene product from transcript GK21128- RA; hypothetical protein 7724292..7725620 Actinosynnema mirum DSM 43827 8330789 YP_003104223.1 CDS Amir_6578 NC_013093.1 7725617 7726342 D hypothetical protein 7725617..7726342 Actinosynnema mirum DSM 43827 8330790 YP_003104224.1 CDS Amir_6580 NC_013093.1 7726642 7728201 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proprotein convertase P; proteinase inhibitor I9 subtilisin propeptide; KEGG: mca:MCA0875 serine protease; peptidase S8/S53 subtilisin kexin sedolisin 7726642..7728201 Actinosynnema mirum DSM 43827 8330792 YP_003104225.1 CDS Amir_6581 NC_013093.1 7728291 7729235 R PFAM: tRNA pseudouridine synthase; KEGG: rpe:RPE_0654 tRNA pseudouridine synthase A; tRNA-pseudouridine synthase I complement(7728291..7729235) Actinosynnema mirum DSM 43827 8330793 YP_003104226.1 CDS Amir_6582 NC_013093.1 7729232 7729822 R TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; KEGG: dol:Dole_0734 ribosomal protein L17; 50S ribosomal protein L17 complement(7729232..7729822) Actinosynnema mirum DSM 43827 8330794 YP_003104227.1 CDS Amir_6583 NC_013093.1 7729881 7730933 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(7729881..7730933) Actinosynnema mirum DSM 43827 8330795 YP_003104228.1 CDS rpsD NC_013093.1 7731079 7731684 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(7731079..7731684) Actinosynnema mirum DSM 43827 8330796 YP_003104229.1 CDS Amir_6585 NC_013093.1 7731708 7732115 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(7731708..7732115) Actinosynnema mirum DSM 43827 8330797 YP_003104230.1 CDS Amir_6586 NC_013093.1 7732148 7732528 R PFAM: ribosomal protein S13; KEGG: gsu:GSU2834 30S ribosomal protein S13; 30S ribosomal protein S13 complement(7732148..7732528) Actinosynnema mirum DSM 43827 8330798 YP_003104231.1 CDS Amir_6587 NC_013093.1 7732746 7732859 R TIGRFAM: ribosomal protein L36; PFAM: ribosomal protein L36; KEGG: aba:Acid345_1250 LSU ribosomal protein L36P; 50S ribosomal protein L36 complement(7732746..7732859) Actinosynnema mirum DSM 43827 8330799 YP_003104232.1 CDS Amir_6588 NC_013093.1 7732910 7733131 R TIGRFAM: translation initiation factor IF-1; PFAM: S1 IF1 family protein; KEGG: bha:BH0158 translation initiation factor IF-1; translation initiation factor IF-1 complement(7732910..7733131) Actinosynnema mirum DSM 43827 8330800 YP_003104233.1 CDS Amir_6589 NC_013093.1 7733284 7733841 R KEGG: mpo:Mpop_2819 translation initiation factor IF-2; hypothetical protein complement(7733284..7733841) Actinosynnema mirum DSM 43827 8330801 YP_003104234.1 CDS Amir_6590 NC_013093.1 7733872 7734348 R PFAM: protein of unknown function DUF1707; hypothetical protein complement(7733872..7734348) Actinosynnema mirum DSM 43827 8330802 YP_003104235.1 CDS Amir_6591 NC_013093.1 7734533 7734664 D hypothetical protein 7734533..7734664 Actinosynnema mirum DSM 43827 8330803 YP_003104236.1 CDS Amir_6592 NC_013093.1 7734801 7735577 R TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: bha:BH0156 methionine aminopeptidase; methionine aminopeptidase, type I complement(7734801..7735577) Actinosynnema mirum DSM 43827 8330804 YP_003104237.1 CDS Amir_6593 NC_013093.1 7735631 7736182 R TIGRFAM: adenylate kinase; PFAM: adenylate kinase; KEGG: sml:Smlt3886 adenylate kinase (fragment); adenylate kinase complement(7735631..7736182) Actinosynnema mirum DSM 43827 8330805 YP_003104238.1 CDS secY NC_013093.1 7736183 7737493 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(7736183..7737493) Actinosynnema mirum DSM 43827 8330806 YP_003104239.1 CDS Amir_6595 NC_013093.1 7738012 7738455 R TIGRFAM: ribosomal protein L15; PFAM: ribosomal protein L15; KEGG: sfu:Sfum_1574 ribosomal protein L15; 50S ribosomal protein L15 complement(7738012..7738455) Actinosynnema mirum DSM 43827 8330807 YP_003104240.1 CDS Amir_6596 NC_013093.1 7738452 7738637 R TIGRFAM: ribosomal protein L30; PFAM: ribosomal protein L30; KEGG: bbr:BB0049 50S ribosomal protein L30; 50S ribosomal protein L30 complement(7738452..7738637) Actinosynnema mirum DSM 43827 8330808 YP_003104241.1 CDS rpsE NC_013093.1 7738640 7739245 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(7738640..7739245) Actinosynnema mirum DSM 43827 8330809 YP_003104242.1 CDS Amir_6598 NC_013093.1 7739280 7739678 R TIGRFAM: ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; KEGG: bsu:BSU01320 50S ribosomal protein L18; 50S ribosomal protein L18 complement(7739280..7739678) Actinosynnema mirum DSM 43827 8330810 YP_003104243.1 CDS Amir_6599 NC_013093.1 7739680 7740219 R PFAM: ribosomal protein L6; KEGG: cak:Caul_1629 50S ribosomal protein L6; 50S ribosomal protein L6 complement(7739680..7740219) Actinosynnema mirum DSM 43827 8330811 YP_003104244.1 CDS Amir_6600 NC_013093.1 7740237 7740635 R PFAM: ribosomal protein S8; KEGG: bha:BH0148 30S ribosomal protein S8; 30S ribosomal protein S8 complement(7740237..7740635) Actinosynnema mirum DSM 43827 8330812 YP_003104245.1 CDS Amir_6601 NC_013093.1 7740776 7740961 R PFAM: ribosomal protein S14; KEGG: cju:C8J_1598 30S ribosomal protein S14; 30S ribosomal protein S14 complement(7740776..7740961) Actinosynnema mirum DSM 43827 8330813 YP_003104246.1 CDS Amir_6602 NC_013093.1 7740965 7741528 R PFAM: ribosomal protein L5; KEGG: csa:Csal_0433 50S ribosomal protein L5; 50S ribosomal protein L5 complement(7740965..7741528) Actinosynnema mirum DSM 43827 8330814 YP_003104247.1 CDS rplX NC_013093.1 7741528 7741842 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(7741528..7741842) Actinosynnema mirum DSM 43827 8330815 YP_003104248.1 CDS Amir_6604 NC_013093.1 7741845 7742213 R TIGRFAM: ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; KEGG: bcy:Bcer98_0114 50S ribosomal protein L14; 50S ribosomal protein L14 complement(7741845..7742213) Actinosynnema mirum DSM 43827 8330816 YP_003104249.1 CDS Amir_6605 NC_013093.1 7742276 7742557 R PFAM: ribosomal protein S17; KEGG: bsu:BSU01250 30S ribosomal protein S17; 30S ribosomal protein S17 complement(7742276..7742557) Actinosynnema mirum DSM 43827 8330817 YP_003104250.1 CDS Amir_6606 NC_013093.1 7742554 7742802 R TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: bha:BH0142 50S ribosomal protein L29; 50S ribosomal protein L29 complement(7742554..7742802) Actinosynnema mirum DSM 43827 8330818 YP_003104251.1 CDS Amir_6607 NC_013093.1 7742802 7743221 R TIGRFAM: ribosomal protein L16; PFAM: ribosomal protein L16; KEGG: bha:BH0141 50S ribosomal protein L16; 50S ribosomal protein L16 complement(7742802..7743221) Actinosynnema mirum DSM 43827 8330819 YP_003104252.1 CDS Amir_6608 NC_013093.1 7743225 7744052 R KEGG: atc:AGR_C_3546 30S ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; KH type 2 domain protein; ribosomal protein S3 domain; SMART: KH domain protein; 30S ribosomal protein S3 complement(7743225..7744052) Actinosynnema mirum DSM 43827 8330820 YP_003104253.1 CDS Amir_6609 NC_013093.1 7744052 7744453 R TIGRFAM: ribosomal protein L22; PFAM: ribosomal protein L22/L17; KEGG: bcu:BCAH820_0127 ribosomal protein L22; 50S ribosomal protein L22 complement(7744052..7744453) Actinosynnema mirum DSM 43827 8330821 YP_003104254.1 CDS Amir_6610 NC_013093.1 7744489 7744770 R TIGRFAM: ribosomal protein S19; PFAM: ribosomal protein S19/S15; KEGG: bha:BH0138 30S ribosomal protein S19; 30S ribosomal protein S19 complement(7744489..7744770) Actinosynnema mirum DSM 43827 8330822 YP_003104255.1 CDS rplB NC_013093.1 7744789 7745622 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(7744789..7745622) Actinosynnema mirum DSM 43827 8330823 YP_003104256.1 CDS rplW NC_013093.1 7745645 7745944 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(7745645..7745944) Actinosynnema mirum DSM 43827 8330824 YP_003104257.1 CDS Amir_6613 NC_013093.1 7745941 7746636 R PFAM: ribosomal protein L4/L1e; KEGG: bha:BH0135 50S ribosomal protein L4; 50S ribosomal protein L4/L1e complement(7745941..7746636) Actinosynnema mirum DSM 43827 8330825 YP_003104258.1 CDS Amir_6614 NC_013093.1 7746639 7747289 R PFAM: ribosomal protein L3; KEGG: sde:Sde_0960 50S ribosomal protein L3P; 50S ribosomal protein L3 complement(7746639..7747289) Actinosynnema mirum DSM 43827 8330826 YP_003104259.1 CDS rpsJ NC_013093.1 7747341 7747646 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(7747341..7747646) Actinosynnema mirum DSM 43827 8330827 YP_003104260.1 CDS Amir_6616 NC_013093.1 7747990 7749183 R KEGG: ppd:Ppro_0678 elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain protein; elongation factor Tu domain 2 protein; translation elongation factor Tu complement(7747990..7749183) Actinosynnema mirum DSM 43827 8330828 YP_003104261.1 CDS Amir_6617 NC_013093.1 7749321 7751423 R TIGRFAM: translation elongation factor G; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: hac:Hac_1575 elongation factor G; translation elongation factor G complement(7749321..7751423) Actinosynnema mirum DSM 43827 8330829 YP_003104262.1 CDS Amir_6618 NC_013093.1 7751511 7751981 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(7751511..7751981) Actinosynnema mirum DSM 43827 8330830 YP_003104263.1 CDS rpsL NC_013093.1 7751981 7752355 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(7751981..7752355) Actinosynnema mirum DSM 43827 8330831 YP_003104264.1 CDS Amir_6620 NC_013093.1 7752965 7753294 D KEGG: similar to pinin; hypothetical protein 7752965..7753294 Actinosynnema mirum DSM 43827 8330832 YP_003104265.1 CDS Amir_6621 NC_013093.1 7753306 7753608 D hypothetical protein 7753306..7753608 Actinosynnema mirum DSM 43827 8330833 YP_003104266.1 CDS Amir_6622 NC_013093.1 7754414 7754569 R hypothetical protein complement(7754414..7754569) Actinosynnema mirum DSM 43827 8330834 YP_003104267.1 CDS Amir_6624 NC_013093.1 7755319 7756191 D PFAM: aminoglycoside phosphotransferase; KEGG: mch:Mchl_5542 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 7755319..7756191 Actinosynnema mirum DSM 43827 8330836 YP_003104268.1 CDS Amir_6625 NC_013093.1 7756228 7756521 D KEGG: tbd:Tbd_1197 hypothetical protein; hypothetical protein 7756228..7756521 Actinosynnema mirum DSM 43827 8330837 YP_003104269.1 CDS Amir_6626 NC_013093.1 7756765 7760661 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(7756765..7760661) Actinosynnema mirum DSM 43827 8330838 YP_003104270.1 CDS rpoB NC_013093.1 7760779 7764261 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(7760779..7764261) Actinosynnema mirum DSM 43827 8330839 YP_003104271.1 CDS Amir_6628 NC_013093.1 7764674 7765789 R KEGG: fibrocystin-L-like protein; hypothetical protein complement(7764674..7765789) Actinosynnema mirum DSM 43827 8330840 YP_003104272.1 CDS Amir_6629 NC_013093.1 7765804 7766697 R KEGG: PF9; flagellar inner arm dynein 1 heavy chain alpha; hypothetical protein complement(7765804..7766697) Actinosynnema mirum DSM 43827 8330841 YP_003104273.1 CDS Amir_6630 NC_013093.1 7766708 7768123 R KEGG: rce:RC1_1665 HAMP domain protein; ABC transporter periplasmic protein complement(7766708..7768123) Actinosynnema mirum DSM 43827 8330842 YP_003104274.1 CDS Amir_6631 NC_013093.1 7768123 7768476 R PFAM: Mammalian cell entry related domain protein; KEGG: rce:RC1_0924 ABC transporter substrate binding protein; mammalian cell entry related domain-containing protein complement(7768123..7768476) Actinosynnema mirum DSM 43827 8330843 YP_003104275.1 CDS Amir_6632 NC_013093.1 7768478 7769464 R PFAM: Mammalian cell entry related domain protein; KEGG: gme:Gmet_1272 virulence factor MCE-like protein-related protein; Mammalian cell entry related domain-containing protein complement(7768478..7769464) Actinosynnema mirum DSM 43827 8330844 YP_003104276.1 CDS Amir_6633 NC_013093.1 7769461 7770300 R PFAM: protein of unknown function DUF140; KEGG: ank:AnaeK_1997 protein of unknown function DUF140; hypothetical protein complement(7769461..7770300) Actinosynnema mirum DSM 43827 8330845 YP_003104277.1 CDS Amir_6634 NC_013093.1 7770302 7771084 R PFAM: protein of unknown function DUF140; KEGG: ade:Adeh_1863 ABC amino acid transporter, inner membrane subunit; hypothetical protein complement(7770302..7771084) Actinosynnema mirum DSM 43827 8330846 YP_003104278.1 CDS Amir_6635 NC_013093.1 7771081 7772172 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sat:SYN_00410 ABC-type transport system, ATP- binding component; ABC transporter complement(7771081..7772172) Actinosynnema mirum DSM 43827 8330847 YP_003104279.1 CDS Amir_6636 NC_013093.1 7772363 7772746 R TIGRFAM: ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12; KEGG: bha:BH0122 50S ribosomal protein L7/L12; 50S ribosomal protein L7/L12 complement(7772363..7772746) Actinosynnema mirum DSM 43827 8330848 YP_003104280.1 CDS Amir_6637 NC_013093.1 7772809 7773363 R PFAM: ribosomal protein L10; KEGG: gox:GOX0388 50S ribosomal protein L10P; 50S ribosomal protein L10 complement(7772809..7773363) Actinosynnema mirum DSM 43827 8330849 YP_003104281.1 CDS Amir_6638 NC_013093.1 7773626 7774561 D KEGG: rpa:RPA0213 OmpA family protein; hypothetical protein 7773626..7774561 Actinosynnema mirum DSM 43827 8330850 YP_003104282.1 CDS rplA NC_013093.1 7774640 7775356 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(7774640..7775356) Actinosynnema mirum DSM 43827 8330851 YP_003104283.1 CDS rplK NC_013093.1 7775451 7775885 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(7775451..7775885) Actinosynnema mirum DSM 43827 8330852 YP_003104284.1 CDS Amir_6641 NC_013093.1 7775994 7776794 R KEGG: bha:BH0118 transcription antitermination protein NusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: NGN domain protein; KOW domain protein; SMART: NGN domain protein; NusG antitermination factor complement(7775994..7776794) Actinosynnema mirum DSM 43827 8330853 YP_003104285.1 CDS Amir_6642 NC_013093.1 7776880 7777290 R TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; KEGG: sfu:Sfum_1543 preprotein translocase, SecE subunit; preprotein translocase subunit SecE complement(7776880..7777290) Actinosynnema mirum DSM 43827 8330854 YP_003104286.1 CDS Amir_6643 NC_013093.1 7777575 7778816 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 7777575..7778816 Actinosynnema mirum DSM 43827 8330856 YP_003104287.1 CDS Amir_6644 NC_013093.1 7779054 7779665 D KEGG: xom:XOO_0364 hypothetical protein; hypothetical protein 7779054..7779665 Actinosynnema mirum DSM 43827 8330857 YP_003104288.1 CDS Amir_6645 NC_013093.1 7779776 7780174 D hypothetical protein 7779776..7780174 Actinosynnema mirum DSM 43827 8330858 YP_003104289.1 CDS Amir_6646 NC_013093.1 7780241 7780660 R PFAM: MaoC domain protein dehydratase; KEGG: dal:Dalk_1161 MaoC domain protein dehydratase; MaoC domain-containing protein dehydratase complement(7780241..7780660) Actinosynnema mirum DSM 43827 8330859 YP_003104290.1 CDS Amir_6647 NC_013093.1 7780657 7781103 R KEGG: rpt:Rpal_3723 hypothetical protein; hypothetical protein complement(7780657..7781103) Actinosynnema mirum DSM 43827 8330860 YP_003104291.1 CDS Amir_6648 NC_013093.1 7781176 7781340 R TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; KEGG: ribosomal protein L33; K02913 large subunit ribosomal protein L33; 50S ribosomal protein L33 complement(7781176..7781340) Actinosynnema mirum DSM 43827 8330861 YP_003104292.1 CDS Amir_6649 NC_013093.1 7781913 7784528 R KEGG: xac:XAC2711 phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; diguanylate cyclase/phosphodiesterase with GAF sensor complement(7781913..7784528) Actinosynnema mirum DSM 43827 8330864 YP_003104293.1 CDS Amir_6650 NC_013093.1 7785339 7785860 R KEGG: bpm:BURPS1710b_A0674 hypothetical protein; hypothetical protein complement(7785339..7785860) Actinosynnema mirum DSM 43827 8330865 YP_003104294.1 CDS Amir_6651 NC_013093.1 7786131 7786376 D hypothetical protein 7786131..7786376 Actinosynnema mirum DSM 43827 8330866 YP_003104295.1 CDS Amir_6652 NC_013093.1 7786481 7787404 R KEGG: sml:Smlt3065 hypothetical protein; hypothetical protein complement(7786481..7787404) Actinosynnema mirum DSM 43827 8330867 YP_003104296.1 CDS Amir_6653 NC_013093.1 7787680 7788171 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 7787680..7788171 Actinosynnema mirum DSM 43827 8330869 YP_003104297.1 CDS Amir_6654 NC_013093.1 7788168 7789046 D TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: pcr:Pcryo_0625 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase 7788168..7789046 Actinosynnema mirum DSM 43827 8330870 YP_003104298.1 CDS Amir_6655 NC_013093.1 7789078 7789938 R PFAM: peptidase M48 Ste24p; KEGG: bxe:Bxe_A4413 heat shock protein HtpX; peptidase M48 Ste24p complement(7789078..7789938) Actinosynnema mirum DSM 43827 8330871 YP_003104299.1 CDS Amir_6656 NC_013093.1 7789973 7790494 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ank:AnaeK_1272 4Fe-4S ferredoxin iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(7789973..7790494) Actinosynnema mirum DSM 43827 8330872 YP_003104300.1 CDS Amir_6657 NC_013093.1 7790487 7791077 R PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: mrd:Mrad2831_2058 NADH (or F420H2) dehydrogenase, subunit C; NADH dehydrogenase (ubiquinone) 30 kDa subunit complement(7790487..7791077) Actinosynnema mirum DSM 43827 8330873 YP_003104301.1 CDS Amir_6658 NC_013093.1 7791077 7791490 R TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: gbm:Gbem_3925 NADH-quinone oxidoreductase, B subunit; NADH-quinone oxidoreductase subunit B complement(7791077..7791490) Actinosynnema mirum DSM 43827 8330874 YP_003104302.1 CDS Amir_6659 NC_013093.1 7791736 7792779 D PFAM: regulatory protein LysR; KEGG: rpb:RPB_4498 hypothetical protein; LysR family transcriptional regulator 7791736..7792779 Actinosynnema mirum DSM 43827 8330875 YP_003104303.1 CDS Amir_6660 NC_013093.1 7792776 7792925 R hypothetical protein complement(7792776..7792925) Actinosynnema mirum DSM 43827 8330876 YP_003104304.1 CDS Amir_6661 NC_013093.1 7793666 7794544 R PFAM: amidinotransferase; KEGG: aeh:Mlg_0130 amidinotransferase; amidinotransferase complement(7793666..7794544) Actinosynnema mirum DSM 43827 8330877 YP_003104305.1 CDS Amir_6662 NC_013093.1 7794611 7795060 D PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: bvi:Bcep1808_5003 AsnC family transcriptional regulator; AsnC family transcriptional regulator 7794611..7795060 Actinosynnema mirum DSM 43827 8330878 YP_003104306.1 CDS Amir_6663 NC_013093.1 7795205 7795966 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 7795205..7795966 Actinosynnema mirum DSM 43827 8330879 YP_003104307.1 CDS Amir_6664 NC_013093.1 7796218 7798101 D PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: eba:ebA3149 2-oxoglutarate ferredoxin oxidoreductase alpha subunit; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein 7796218..7798101 Actinosynnema mirum DSM 43827 8330880 YP_003104308.1 CDS Amir_6665 NC_013093.1 7798098 7799141 D PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: eba:ebA3150 2-oxoglutarate ferredoxin oxidoreductase subunit beta; thiamine pyrophosphate TPP-binding domain-containing protein 7798098..7799141 Actinosynnema mirum DSM 43827 8330881 YP_003104309.1 CDS Amir_6666 NC_013093.1 7799222 7801828 R KEGG: hypothetical protein; hypothetical protein complement(7799222..7801828) Actinosynnema mirum DSM 43827 8330882 YP_003104310.1 CDS Amir_6667 NC_013093.1 7802025 7802966 D TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: cvi:CV_0304 RarD protein, chloamphenicol sensitive; RarD protein, DMT superfamily transporter 7802025..7802966 Actinosynnema mirum DSM 43827 8330883 YP_003104311.1 CDS Amir_6668 NC_013093.1 7803110 7804111 R PFAM: polyprenyl synthetase; KEGG: sit:TM1040_3742 farnesyltranstransferase; polyprenyl synthetase complement(7803110..7804111) Actinosynnema mirum DSM 43827 8330884 YP_003104312.1 CDS Amir_6669 NC_013093.1 7804133 7805716 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(7804133..7805716) Actinosynnema mirum DSM 43827 8330885 YP_003104313.1 CDS Amir_6670 NC_013093.1 7805718 7807280 R KEGG: mgm:Mmc1_3623 proton-translocating NADH- quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); proton-translocating NADH-quinone oxidoreductase subunit M complement(7805718..7807280) Actinosynnema mirum DSM 43827 8330886 YP_003104314.1 CDS Amir_6671 NC_013093.1 7807277 7809211 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(7807277..7809211) Actinosynnema mirum DSM 43827 8330887 YP_003104315.1 CDS Amir_6672 NC_013093.1 7809222 7809521 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(7809222..7809521) Actinosynnema mirum DSM 43827 8330888 YP_003104316.1 CDS Amir_6673 NC_013093.1 7809518 7810351 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(7809518..7810351) Actinosynnema mirum DSM 43827 8330889 YP_003104317.1 CDS Amir_6674 NC_013093.1 7810348 7810914 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(7810348..7810914) Actinosynnema mirum DSM 43827 8330890 YP_003104318.1 CDS Amir_6675 NC_013093.1 7810901 7812244 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(7810901..7812244) Actinosynnema mirum DSM 43827 8330891 YP_003104319.1 CDS Amir_6676 NC_013093.1 7812241 7814688 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(7812241..7814688) Actinosynnema mirum DSM 43827 8330892 YP_003104320.1 CDS Amir_6677 NC_013093.1 7814685 7815980 R KEGG: sme:SMa1525 NuoF2 NADH I chain F; TIGRFAM: NADH-quinone oxidoreductase, F subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH-quinone oxidoreductase subunit F complement(7814685..7815980) Actinosynnema mirum DSM 43827 8330893 YP_003104321.1 CDS Amir_6678 NC_013093.1 7815990 7816754 R PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: mag:amb2783 NADH:ubiquinone oxidoreductase 24 kD subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit complement(7815990..7816754) Actinosynnema mirum DSM 43827 8330894 YP_003104322.1 CDS Amir_6679 NC_013093.1 7816751 7818202 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D complement(7816751..7818202) Actinosynnema mirum DSM 43827 8330895 YP_003104323.1 CDS Amir_6680 NC_013093.1 7818199 7818957 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C complement(7818199..7818957) Actinosynnema mirum DSM 43827 8330896 YP_003104324.1 CDS Amir_6681 NC_013093.1 7818963 7819511 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(7818963..7819511) Actinosynnema mirum DSM 43827 8330897 YP_003104325.1 CDS Amir_6682 NC_013093.1 7819523 7819888 R PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; KEGG: glo:Glov_3138 NADH-ubiquinone/plastoquinone oxidoreductase chain 3; NADH-ubiquinone/plastoquinone oxidoreductase chain 3 complement(7819523..7819888) Actinosynnema mirum DSM 43827 8330898 YP_003104326.1 CDS Amir_6683 NC_013093.1 7820237 7821517 R TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase; KEGG: pna:Pnap_1343 geranylgeranyl reductase; geranylgeranyl reductase complement(7820237..7821517) Actinosynnema mirum DSM 43827 8330899 YP_003104327.1 CDS Amir_6684 NC_013093.1 7822409 7823101 R TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: sgl:SG0109 ubiquinone/menaquinone biosynthesis methyltransferase; ubiquinone/menaquinone biosynthesis methyltransferase complement(7822409..7823101) Actinosynnema mirum DSM 43827 8330900 YP_003104328.1 CDS Amir_6685 NC_013093.1 7823259 7824083 D PFAM: inositol monophosphatase; KEGG: ade:Adeh_3387 inositol-1(or 4)- monophosphatase; inositol monophosphatase 7823259..7824083 Actinosynnema mirum DSM 43827 8330901 YP_003104329.1 CDS Amir_6686 NC_013093.1 7824056 7824169 D hypothetical protein 7824056..7824169 Actinosynnema mirum DSM 43827 8330902 YP_003104330.1 CDS Amir_6687 NC_013093.1 7824156 7824836 R KEGG: predicted protein; hypothetical protein complement(7824156..7824836) Actinosynnema mirum DSM 43827 8330903 YP_003104331.1 CDS Amir_6688 NC_013093.1 7824854 7825879 R TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: azo:azo0308 phenylacetic acid degradation NADH oxidoreductase PaaE; phenylacetate-CoA oxygenase/reductase subunit PaaK complement(7824854..7825879) Actinosynnema mirum DSM 43827 8330904 YP_003104332.1 CDS Amir_6689 NC_013093.1 7825880 7826392 R TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: mno:Mnod_7196 phenylacetate-CoA oxygenase, PaaJ subunit; phenylacetate-CoA oxygenase subunit PaaJ complement(7825880..7826392) Actinosynnema mirum DSM 43827 8330905 YP_003104333.1 CDS Amir_6690 NC_013093.1 7826389 7827342 R TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: rpd:RPD_1826 phenylacetate-CoA oxygenase, PaaI subunit; phenylacetate-CoA oxygenase subunit PaaI complement(7826389..7827342) Actinosynnema mirum DSM 43827 8330906 YP_003104334.1 CDS Amir_6691 NC_013093.1 7827351 7827641 R TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; KEGG: pde:Pden_4809 phenylacetate-CoA oxygenase, PaaH subunit; phenylacetate-CoA oxygenase subunit PaaH complement(7827351..7827641) Actinosynnema mirum DSM 43827 8330907 YP_003104335.1 CDS paaA NC_013093.1 7827638 7828573 R with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA complement(7827638..7828573) Actinosynnema mirum DSM 43827 8330908 YP_003104336.1 CDS Amir_6693 NC_013093.1 7828617 7829168 R hypothetical protein complement(7828617..7829168) Actinosynnema mirum DSM 43827 8330909 YP_003104337.1 CDS Amir_6694 NC_013093.1 7829180 7830421 D TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: scl:sce5042 hypothetical protein; isochorismate synthase 7829180..7830421 Actinosynnema mirum DSM 43827 8330910 YP_003104338.1 CDS Amir_6695 NC_013093.1 7830470 7831516 R PFAM: ADP-ribosylation/Crystallin J1; KEGG: dol:Dole_0265 ADP-ribosylation/crystallin J1; ADP-ribosylation/Crystallin J1 complement(7830470..7831516) Actinosynnema mirum DSM 43827 8330911 YP_003104339.1 CDS Amir_6696 NC_013093.1 7831575 7832654 D PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sbp:Sbal223_2267 pyridoxal-5'-phosphate- dependent protein beta subunit; pyridoxal-5'-phosphate-dependent protein beta subunit 7831575..7832654 Actinosynnema mirum DSM 43827 8330912 YP_003104340.1 CDS Amir_6697 NC_013093.1 7832802 7833200 D hypothetical protein 7832802..7833200 Actinosynnema mirum DSM 43827 8330913 YP_003104341.1 CDS Amir_6698 NC_013093.1 7833247 7834119 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(7833247..7834119) Actinosynnema mirum DSM 43827 8330914 YP_003104342.1 CDS Amir_6699 NC_013093.1 7834169 7835416 R KEGG: GD17417 gene product from transcript GD17417- RA; hypothetical protein complement(7834169..7835416) Actinosynnema mirum DSM 43827 8330915 YP_003104343.1 CDS Amir_6700 NC_013093.1 7835532 7836593 R KEGG: dar:Daro_2822 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase complement(7835532..7836593) Actinosynnema mirum DSM 43827 8330916 YP_003104344.1 CDS Amir_6701 NC_013093.1 7836620 7837531 R TIGRFAM: naphthoate synthase; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: scl:sce5310 naphthoate synthase; naphthoate synthase complement(7836620..7837531) Actinosynnema mirum DSM 43827 8330917 YP_003104345.1 CDS Amir_6702 NC_013093.1 7837843 7839477 D TIGRFAM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; KEGG: bcy:Bcer98_3493 2-succinyl-6-hydroxy-2,4- cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase 7837843..7839477 Actinosynnema mirum DSM 43827 8330918 YP_003104346.1 CDS Amir_6703 NC_013093.1 7839546 7841162 D PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: sus:Acid_2560 peptidase M1, membrane alanine aminopeptidase; peptidase M1 membrane alanine aminopeptidase 7839546..7841162 Actinosynnema mirum DSM 43827 8330919 YP_003104347.1 CDS Amir_6704 NC_013093.1 7841222 7841431 R hypothetical protein complement(7841222..7841431) Actinosynnema mirum DSM 43827 8330920 YP_003104348.1 CDS Amir_6705 NC_013093.1 7841578 7842456 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: xca:xccb100_3044 transcriptional regulator; helix-turn-helix domain-containing protein 7841578..7842456 Actinosynnema mirum DSM 43827 8330921 YP_003104349.1 CDS Amir_6706 NC_013093.1 7842459 7842638 D PFAM: protein of unknown function DUF397; hypothetical protein 7842459..7842638 Actinosynnema mirum DSM 43827 8330922 YP_003104350.1 CDS Amir_6707 NC_013093.1 7842819 7843118 R hypothetical protein complement(7842819..7843118) Actinosynnema mirum DSM 43827 8330923 YP_003104351.1 CDS Amir_6708 NC_013093.1 7843123 7843584 R PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: scl:sce5626 leucine responsive regulatory protein; AsnC family transcriptional regulator complement(7843123..7843584) Actinosynnema mirum DSM 43827 8330924 YP_003104352.1 CDS Amir_6709 NC_013093.1 7843734 7843952 D TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; KEGG: cps:CPS_1619 DNA-binding response regulator; excisionase family DNA binding domain-containing protein 7843734..7843952 Actinosynnema mirum DSM 43827 8330925 YP_003104353.1 CDS Amir_6710 NC_013093.1 7844081 7844263 D hypothetical protein 7844081..7844263 Actinosynnema mirum DSM 43827 8330926 YP_003104354.1 CDS Amir_6711 NC_013093.1 7844485 7845972 R KEGG: GG20667 gene product from transcript GG20667- RA; chromosome partitioning ATPase complement(7844485..7845972) Actinosynnema mirum DSM 43827 8330927 YP_003104355.1 CDS Amir_6712 NC_013093.1 7846106 7847071 R TIGRFAM: cytochrome C-type biogenesis protein CcsB; PFAM: cytochrome C assembly protein; KEGG: pca:Pcar_3065 cytochrome C biogenesis protein; cytochrome C biogenesis protein CcsB complement(7846106..7847071) Actinosynnema mirum DSM 43827 8330928 YP_003104356.1 CDS Amir_6713 NC_013093.1 7847071 7848627 R PFAM: ResB family protein; KEGG: cvi:CV_4387 cytochrome C-type biogenesis protein; ResB family protein complement(7847071..7848627) Actinosynnema mirum DSM 43827 8330929 YP_003104357.1 CDS Amir_6714 NC_013093.1 7848627 7849427 R PFAM: cytochrome C biogenesis protein transmembrane region; KEGG: rpd:RPD_4260 cytochrome C biogenesis protein, transmembrane region; cytochrome c biogenesis protein transmembrane protein complement(7848627..7849427) Actinosynnema mirum DSM 43827 8330930 YP_003104358.1 CDS Amir_6715 NC_013093.1 7849526 7850587 D KEGG: hch:HCH_01837 fibronectin type III domain- containing protein; hypothetical protein 7849526..7850587 Actinosynnema mirum DSM 43827 8330931 YP_003104359.1 CDS Amir_6716 NC_013093.1 7850973 7851947 R PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: mlo:mll2594 quinone oxidoreductase; alcohol dehydrogenase GroES domain-containing protein complement(7850973..7851947) Actinosynnema mirum DSM 43827 8330932 YP_003104360.1 CDS Amir_6717 NC_013093.1 7851985 7852572 R PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sfr:Sfri_1234 redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen complement(7851985..7852572) Actinosynnema mirum DSM 43827 8330933 YP_003104361.1 CDS Amir_6718 NC_013093.1 7852569 7853198 R PFAM: phosphoglycerate mutase; KEGG: afr:AFE_0621 phosphoglycerate mutase family protein; phosphoglycerate mutase complement(7852569..7853198) Actinosynnema mirum DSM 43827 8330934 YP_003104362.1 CDS Amir_6719 NC_013093.1 7853195 7854490 R TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; aminotransferase class I and II; KEGG: bbr:BB4409 glutamate-1-semialdehyde 2,1- aminomutase; glutamate-1-semialdehyde-2,1-aminomutase complement(7853195..7854490) Actinosynnema mirum DSM 43827 8330935 YP_003104363.1 CDS Amir_6720 NC_013093.1 7854596 7855090 R KEGG: Hypothetical protein CBG04716; hypothetical protein complement(7854596..7855090) Actinosynnema mirum DSM 43827 8330936 YP_003104364.1 CDS Amir_6721 NC_013093.1 7855104 7855547 R hypothetical protein complement(7855104..7855547) Actinosynnema mirum DSM 43827 8330937 YP_003104365.1 CDS Amir_6722 NC_013093.1 7855550 7856329 R KEGG: hypothetical protein; hypothetical protein complement(7855550..7856329) Actinosynnema mirum DSM 43827 8330938 YP_003104366.1 CDS Amir_6723 NC_013093.1 7856479 7856997 R hypothetical protein complement(7856479..7856997) Actinosynnema mirum DSM 43827 8330939 YP_003104367.1 CDS Amir_6724 NC_013093.1 7857069 7857671 R KEGG: hypothetical protein; hypothetical protein complement(7857069..7857671) Actinosynnema mirum DSM 43827 8330940 YP_003104368.1 CDS Amir_6725 NC_013093.1 7857770 7858387 R KEGG: scl:sce6476 hypothetical protein; hypothetical protein complement(7857770..7858387) Actinosynnema mirum DSM 43827 8330941 YP_003104369.1 CDS Amir_6726 NC_013093.1 7858442 7859068 R hypothetical protein complement(7858442..7859068) Actinosynnema mirum DSM 43827 8330942 YP_003104370.1 CDS Amir_6727 NC_013093.1 7859068 7860042 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(7859068..7860042) Actinosynnema mirum DSM 43827 8330943 YP_003104371.1 CDS Amir_6728 NC_013093.1 7860477 7862009 R PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrinogen III synthase HEM4; KEGG: sfu:Sfum_3201 uroporphyrin-III C- methyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase complement(7860477..7862009) Actinosynnema mirum DSM 43827 8330944 YP_003104372.1 CDS hemC NC_013093.1 7862024 7862965 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(7862024..7862965) Actinosynnema mirum DSM 43827 8330945 YP_003104373.1 CDS hemA NC_013093.1 7862962 7864278 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(7862962..7864278) Actinosynnema mirum DSM 43827 8330946 YP_003104374.1 CDS Amir_6731 NC_013093.1 7864325 7865095 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(7864325..7865095) Actinosynnema mirum DSM 43827 8330947 YP_003104375.1 CDS Amir_6732 NC_013093.1 7865360 7866010 R PFAM: beta-Ig-H3/fasciclin; SMART: beta-Ig-H3/fasciclin; KEGG: rpe:RPE_0476 beta-Ig-H3/fasciclin; beta-Ig-H3/fasciclin complement(7865360..7866010) Actinosynnema mirum DSM 43827 8330948 YP_003104376.1 CDS Amir_6733 NC_013093.1 7866093 7867919 R PFAM: oxidoreductase molybdopterin binding; KEGG: sme:SMa2103 oxidoreductase; molybdopterin binding oxidoreductase complement(7866093..7867919) Actinosynnema mirum DSM 43827 8330949 YP_003104377.1 CDS Amir_6734 NC_013093.1 7867972 7868208 R PFAM: glutaredoxin 2; KEGG: bpy:Bphyt_2902 glutaredoxin 2; glutaredoxin 2 complement(7867972..7868208) Actinosynnema mirum DSM 43827 8330950 YP_003104378.1 CDS Amir_6735 NC_013093.1 7868225 7869736 R PFAM: AMP-dependent synthetase and ligase; KEGG: mno:Mnod_7251 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase complement(7868225..7869736) Actinosynnema mirum DSM 43827 8330951 YP_003104379.1 CDS Amir_6736 NC_013093.1 7869928 7870581 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: aba:Acid345_3132 sigma-24, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 7869928..7870581 Actinosynnema mirum DSM 43827 8330952 YP_003104380.1 CDS Amir_6737 NC_013093.1 7870668 7871897 D KEGG: ank:AnaeK_2468 hypothetical protein; hypothetical protein 7870668..7871897 Actinosynnema mirum DSM 43827 8330953 YP_003104381.1 CDS Amir_6738 NC_013093.1 7871938 7872822 D TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase- like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pag:PLES_41761 phosphoserine phosphatase; HAD superfamily hydrolase 7871938..7872822 Actinosynnema mirum DSM 43827 8330954 YP_003104382.1 CDS Amir_6739 NC_013093.1 7872970 7873968 R PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: dal:Dalk_1813 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase complement(7872970..7873968) Actinosynnema mirum DSM 43827 8330955 YP_003104383.1 CDS Amir_6740 NC_013093.1 7874159 7875196 R PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; short-chain dehydrogenase/reductase SDR; KEGG: dal:Dalk_1814 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase complement(7874159..7875196) Actinosynnema mirum DSM 43827 8330956 YP_003104384.1 CDS Amir_6741 NC_013093.1 7875526 7875627 R PFAM: Protein of unknown function DUF1713; hypothetical protein complement(7875526..7875627) Actinosynnema mirum DSM 43827 8330957 YP_003104385.1 CDS Amir_6742 NC_013093.1 7875795 7876007 R TIGRFAM: DNA binding domain protein, excisionase family; KEGG: afw:Anae109_1068 DNA binding domain- containing protein; excisionase family DNA binding domain-containing protein complement(7875795..7876007) Actinosynnema mirum DSM 43827 8330958 YP_003104386.1 CDS Amir_6743 NC_013093.1 7876189 7877001 R KEGG: mgm:Mmc1_3656 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; ketopantoate reductase ApbA/PanE domain protein; pyrroline-5-carboxylate reductase complement(7876189..7877001) Actinosynnema mirum DSM 43827 8330959 YP_003104387.1 CDS Amir_6744 NC_013093.1 7877468 7878274 R PFAM: thioesterase superfamily protein; KEGG: dal:Dalk_1857 hypothetical protein; thioesterase superfamily protein complement(7877468..7878274) Actinosynnema mirum DSM 43827 8330960 YP_003104388.1 CDS Amir_6745 NC_013093.1 7878310 7879170 R PFAM: proline dehydrogenase; KEGG: mxa:MXAN_7405 proline dehydrogenase; proline dehydrogenase complement(7878310..7879170) Actinosynnema mirum DSM 43827 8330961 YP_003104389.1 CDS Amir_6746 NC_013093.1 7879181 7879999 R PFAM: xylose isomerase; KEGG: gbm:Gbem_1512 xylose isomerase domain protein TIM barrel; xylose isomerase complement(7879181..7879999) Actinosynnema mirum DSM 43827 8330962 YP_003104390.1 CDS Amir_6747 NC_013093.1 7879996 7881438 R KEGG: hypothetical protein; hypothetical protein complement(7879996..7881438) Actinosynnema mirum DSM 43827 8330963 YP_003104391.1 CDS Amir_6748 NC_013093.1 7881438 7882457 R PFAM: Ppx/GppA phosphatase; KEGG: afw:Anae109_0702 Ppx/GppA phosphatase; Ppx/GppA phosphatase complement(7881438..7882457) Actinosynnema mirum DSM 43827 8330964 YP_003104392.1 CDS Amir_6749 NC_013093.1 7882476 7883156 R PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcb:BCB4264_A5589 DNA-binding response regulator YycF; winged helix family two component transcriptional regulator complement(7882476..7883156) Actinosynnema mirum DSM 43827 8330965 YP_003104393.1 CDS Amir_6750 NC_013093.1 7883153 7884337 R KEGG: glo:Glov_0589 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase complement(7883153..7884337) Actinosynnema mirum DSM 43827 8330966 YP_003104394.1 CDS Amir_6751 NC_013093.1 7884446 7885273 R PFAM: aldo/keto reductase; KEGG: reu:Reut_A0010 oxidoreductase; aldo/keto reductase complement(7884446..7885273) Actinosynnema mirum DSM 43827 8330967 YP_003104395.1 CDS Amir_6752 NC_013093.1 7885352 7885987 D KEGG: maq:Maqu_0164 response regulator receiver protein; response regulator receiver protein 7885352..7885987 Actinosynnema mirum DSM 43827 8330968 YP_003104396.1 CDS Amir_6753 NC_013093.1 7886139 7886885 R KEGG: YALI0B02728p; K01834 phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase 1 family; PFAM: phosphoglycerate mutase; phosphoglycerate mutase 1 family complement(7886139..7886885) Actinosynnema mirum DSM 43827 8330969 YP_003104397.1 CDS Amir_6754 NC_013093.1 7887173 7888726 R PFAM: AMP-dependent synthetase and ligase; KEGG: dsh:Dshi_0253 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase complement(7887173..7888726) Actinosynnema mirum DSM 43827 8330970 YP_003104398.1 CDS Amir_6755 NC_013093.1 7889132 7890139 R KEGG: scl:sce1077 hypothetical protein; hypothetical protein complement(7889132..7890139) Actinosynnema mirum DSM 43827 8330971 YP_003104399.1 CDS Amir_6756 NC_013093.1 7890207 7890704 R hypothetical protein complement(7890207..7890704) Actinosynnema mirum DSM 43827 8330972 YP_003104400.1 CDS Amir_6757 NC_013093.1 7890701 7891954 R TIGRFAM: UDP-N-acetylglucosamine; PFAM: glycosyl transferase group 1; KEGG: azo:azo1809 glycosyltransferase; UDP-N-acetylglucosamine complement(7890701..7891954) Actinosynnema mirum DSM 43827 8330973 YP_003104401.1 CDS Amir_6758 NC_013093.1 7892285 7893430 R PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mca:MCA1018 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein complement(7892285..7893430) Actinosynnema mirum DSM 43827 8330974 YP_003104402.1 CDS Amir_6759 NC_013093.1 7893534 7894265 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: scl:sce8093 oxidoreductase; short-chain dehydrogenase/reductase SDR 7893534..7894265 Actinosynnema mirum DSM 43827 8330975 YP_003104403.1 CDS Amir_6760 NC_013093.1 7894219 7895214 R KEGG: noc:Noc_1844 hypothetical protein; hypothetical protein complement(7894219..7895214) Actinosynnema mirum DSM 43827 8330976 YP_003104404.1 CDS Amir_6761 NC_013093.1 7895399 7896451 R PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; FAD linked oxidase domain protein; KEGG: scl:sce7823 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylmuramate dehydrogenase complement(7895399..7896451) Actinosynnema mirum DSM 43827 8330977 YP_003104405.1 CDS Amir_6762 NC_013093.1 7896519 7897016 D KEGG: hch:HCH_06841 hypothetical protein; hypothetical protein 7896519..7897016 Actinosynnema mirum DSM 43827 8330978 YP_003104406.1 CDS Amir_6763 NC_013093.1 7897037 7897792 D KEGG: mxa:MXAN_2356 hypothetical protein; hypothetical protein 7897037..7897792 Actinosynnema mirum DSM 43827 8330979 YP_003104407.1 CDS Amir_6764 NC_013093.1 7898674 7899411 D PFAM: protein of unknown function DUF1503; hypothetical protein 7898674..7899411 Actinosynnema mirum DSM 43827 8330980 YP_003104408.1 CDS purU NC_013093.1 7899435 7900310 D produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 7899435..7900310 Actinosynnema mirum DSM 43827 8330981 YP_003104409.1 CDS Amir_6766 NC_013093.1 7900352 7901434 D KEGG: mxa:MXAN_2885 hypothetical protein; hypothetical protein 7900352..7901434 Actinosynnema mirum DSM 43827 8330982 YP_003104410.1 CDS Amir_6767 NC_013093.1 7901525 7902058 D PFAM: regulatory protein TetR; KEGG: bsu:BSU17080 transcriptional regulator; TetR family transcriptional regulator 7901525..7902058 Actinosynnema mirum DSM 43827 8330983 YP_003104411.1 CDS Amir_6768 NC_013093.1 7902126 7902680 R PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: bbr:BB1555 hypothetical protein; YbaK/prolyl-tRNA synthetase associated protein complement(7902126..7902680) Actinosynnema mirum DSM 43827 8330984 YP_003104412.1 CDS Amir_6769 NC_013093.1 7902855 7903619 D PFAM: TipAS antibiotic-recognition domain protein; regulatory protein MerR; SMART: regulatory protein MerR; KEGG: ccs:CCNA_00730 transcriptional regulator SkgA; MerR family transcriptional regulator 7902855..7903619 Actinosynnema mirum DSM 43827 8330985 YP_003104413.1 CDS Amir_6770 NC_013093.1 7903733 7904281 R TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: psa:PST_4009 protease PfpI; intracellular protease, PfpI family complement(7903733..7904281) Actinosynnema mirum DSM 43827 8330986 YP_003104414.1 CDS Amir_6771 NC_013093.1 7904291 7904956 R KEGG: sal:Sala_0890 flavin reductase-like, FMN- binding; flavin reductase-like FMN-binding protein complement(7904291..7904956) Actinosynnema mirum DSM 43827 8330987 YP_003104415.1 CDS Amir_6772 NC_013093.1 7904953 7905276 R hypothetical protein complement(7904953..7905276) Actinosynnema mirum DSM 43827 8330988 YP_003104416.1 CDS Amir_6773 NC_013093.1 7905496 7906080 R KEGG: hypothetical protein; K03497 chromosome partitioning protein, ParB family; hypothetical protein complement(7905496..7906080) Actinosynnema mirum DSM 43827 8330989 YP_003104417.1 CDS Amir_6774 NC_013093.1 7906086 7906472 R PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: azc:AZC_2073 XRE family-like protein; XRE family transcriptional regulator complement(7906086..7906472) Actinosynnema mirum DSM 43827 8330990 YP_003104418.1 CDS Amir_6775 NC_013093.1 7906577 7907704 D PFAM: protein-L-isoaspartate(D-aspartate) O- methyltransferase; KEGG: mex:Mext_4262 protein-L-isoaspartate O- methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase 7906577..7907704 Actinosynnema mirum DSM 43827 8330991 YP_003104419.1 CDS Amir_6776 NC_013093.1 7908001 7909257 R PFAM: protein of unknown function DUF445; KEGG: swi:Swit_4743 hypothetical protein; hypothetical protein complement(7908001..7909257) Actinosynnema mirum DSM 43827 8330992 YP_003104420.1 CDS Amir_6777 NC_013093.1 7909314 7910459 D PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mxa:MXAN_3751 aminotransferase, classes I and II; class I and II aminotransferase 7909314..7910459 Actinosynnema mirum DSM 43827 8330993 YP_003104421.1 CDS Amir_6778 NC_013093.1 7910463 7912475 R KEGG: pag:PLES_38291 hypothetical protein; hypothetical protein complement(7910463..7912475) Actinosynnema mirum DSM 43827 8330994 YP_003104422.1 CDS Amir_6779 NC_013093.1 7912615 7913043 D KEGG: scl:sce4225 hypothetical protein; hypothetical protein 7912615..7913043 Actinosynnema mirum DSM 43827 8330995 YP_003104423.1 CDS Amir_6780 NC_013093.1 7913148 7913615 R PFAM: protein of unknown function DUF1470; KEGG: sme:SMc00597 hypothetical protein; hypothetical protein complement(7913148..7913615) Actinosynnema mirum DSM 43827 8330996 YP_003104424.1 CDS Amir_6781 NC_013093.1 7913794 7914318 D PFAM: transcriptional regulator PadR family protein; KEGG: nar:Saro_2546 PadR family transcriptional regulator; PadR family transcriptional regulator 7913794..7914318 Actinosynnema mirum DSM 43827 8330997 YP_003104425.1 CDS Amir_6782 NC_013093.1 7914315 7914992 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: tgr:Tgr7_1366 lipoprotein releasing system, ATP-binding protein; ABC transporter 7914315..7914992 Actinosynnema mirum DSM 43827 8330998 YP_003104426.1 CDS Amir_6783 NC_013093.1 7914989 7917349 D PFAM: protein of unknown function DUF214; KEGG: mpt:Mpe_A2047 ABC transporter, permease protein; hypothetical protein 7914989..7917349 Actinosynnema mirum DSM 43827 8330999 YP_003104427.1 CDS Amir_6784 NC_013093.1 7917471 7917581 D hypothetical protein 7917471..7917581 Actinosynnema mirum DSM 43827 8331000 YP_003104428.1 CDS Amir_6785 NC_013093.1 7917578 7919938 D PFAM: protein of unknown function DUF214; KEGG: ank:AnaeK_1836 protein of unknown function DUF214; hypothetical protein 7917578..7919938 Actinosynnema mirum DSM 43827 8331001 YP_003104429.1 CDS Amir_6786 NC_013093.1 7919935 7922148 D PFAM: protein of unknown function DUF214; KEGG: rru:Rru_A3653 hypothetical protein; hypothetical protein 7919935..7922148 Actinosynnema mirum DSM 43827 8331002 YP_003104430.1 CDS Amir_6787 NC_013093.1 7922212 7923312 D KEGG: acp:A2cp1_2390 transcriptional regulator, Fis family; Fis family transcriptional regulator 7922212..7923312 Actinosynnema mirum DSM 43827 8331003 YP_003104431.1 CDS Amir_6789 NC_013093.1 7923983 7925308 D KEGG: proteophosphoglycan 5; hypothetical protein 7923983..7925308 Actinosynnema mirum DSM 43827 8331005 YP_003104432.1 CDS Amir_6790 NC_013093.1 7925861 7927324 R PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: pzu:PHZ_c3113 transcriptional regulator, GntR family; GntR family transcriptional regulator complement(7925861..7927324) Actinosynnema mirum DSM 43827 8331006 YP_003104433.1 CDS Amir_6791 NC_013093.1 7927386 7928015 D PFAM: protein of unknown function DUF161; KEGG: pzu:PHZ_c3114 hypothetical protein; hypothetical protein 7927386..7928015 Actinosynnema mirum DSM 43827 8331007 YP_003104434.1 CDS Amir_6792 NC_013093.1 7927984 7928526 R PFAM: Clp domain protein; KEGG: ATP-dependent clp protease ATP-binding subunit; Clp domain-containing protein complement(7927984..7928526) Actinosynnema mirum DSM 43827 8331008 YP_003104435.1 CDS Amir_6793 NC_013093.1 7928523 7928735 R hypothetical protein complement(7928523..7928735) Actinosynnema mirum DSM 43827 8331009 YP_003104436.1 CDS Amir_6794 NC_013093.1 7928818 7929588 D KEGG: pap:PSPA7_0575 hypothetical protein; hypothetical protein 7928818..7929588 Actinosynnema mirum DSM 43827 8331010 YP_003104437.1 CDS Amir_6795 NC_013093.1 7930622 7930867 R hypothetical protein complement(7930622..7930867) Actinosynnema mirum DSM 43827 8331014 YP_003104438.1 CDS Amir_6796 NC_013093.1 7931033 7931359 D KEGG: similar to corin; hypothetical protein 7931033..7931359 Actinosynnema mirum DSM 43827 8331015 YP_003104439.1 CDS Amir_6797 NC_013093.1 7931418 7931630 D PFAM: Heavy metal transport/detoxification protein; KEGG: dvm:DvMF_3169 heavy metal transport/detoxification protein; Heavy metal transport/detoxification protein 7931418..7931630 Actinosynnema mirum DSM 43827 8331016 YP_003104440.1 CDS Amir_6798 NC_013093.1 7931636 7933855 D TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: bsu:BSU33500 hypothetical protein; heavy metal translocating P-type ATPase 7931636..7933855 Actinosynnema mirum DSM 43827 8331017 YP_003104441.1 CDS Amir_6799 NC_013093.1 7934057 7934374 D hypothetical protein 7934057..7934374 Actinosynnema mirum DSM 43827 8331018 YP_003104442.1 CDS Amir_6800 NC_013093.1 7934557 7934760 R PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mpt:Mpe_A2202 cold-shock DNA-binding protein family protein; cold-shock DNA-binding domain-containing protein complement(7934557..7934760) Actinosynnema mirum DSM 43827 8331019 YP_003104443.1 CDS Amir_6801 NC_013093.1 7934976 7935803 R PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: bsu:BSU27440 glutamine ABC transporter (glutamine-binding protein); family 3 extracellular solute-binding protein complement(7934976..7935803) Actinosynnema mirum DSM 43827 8331020 YP_003104444.1 CDS Amir_6802 NC_013093.1 7936033 7936881 R KEGG: psa:PST_3300 hypothetical protein; hypothetical protein complement(7936033..7936881) Actinosynnema mirum DSM 43827 8331021 YP_003104445.1 CDS Amir_6803 NC_013093.1 7937030 7937704 D KEGG: Os02g0467200; hypothetical protein; hypothetical protein 7937030..7937704 Actinosynnema mirum DSM 43827 8331022 YP_003104446.1 CDS Amir_6804 NC_013093.1 7937775 7942619 R KEGG: scl:sce5242 hypothetical protein; hypothetical protein complement(7937775..7942619) Actinosynnema mirum DSM 43827 8331023 YP_003104447.1 CDS Amir_6805 NC_013093.1 7942616 7944622 R KEGG: mxa:MXAN_3571 hypothetical protein; hypothetical protein complement(7942616..7944622) Actinosynnema mirum DSM 43827 8331024 YP_003104448.1 CDS Amir_6806 NC_013093.1 7944637 7945218 R KEGG: maq:Maqu_3701 hypothetical protein; hypothetical protein complement(7944637..7945218) Actinosynnema mirum DSM 43827 8331025 YP_003104449.1 CDS Amir_6807 NC_013093.1 7945796 7946881 R PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: bac:BamMC406_6306 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein complement(7945796..7946881) Actinosynnema mirum DSM 43827 8331027 YP_003104450.1 CDS Amir_6808 NC_013093.1 7946878 7947345 R KEGG: spe:Spro_1171 hypothetical protein; hypothetical protein complement(7946878..7947345) Actinosynnema mirum DSM 43827 8331028 YP_003104451.1 CDS Amir_6809 NC_013093.1 7947405 7947941 R PFAM: regulatory protein TetR; KEGG: mes:Meso_3334 transcriptional regulator, TetR family; TetR family transcriptional regulator complement(7947405..7947941) Actinosynnema mirum DSM 43827 8331029 YP_003104452.1 CDS Amir_6810 NC_013093.1 7947996 7948826 D hypothetical protein 7947996..7948826 Actinosynnema mirum DSM 43827 8331030 YP_003104453.1 CDS Amir_6811 NC_013093.1 7949037 7950218 D TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: hypothetical protein; TIM-barrel protein, nifR3 family 7949037..7950218 Actinosynnema mirum DSM 43827 8331031 YP_003104454.1 CDS Amir_6812 NC_013093.1 7950211 7950669 D hypothetical protein 7950211..7950669 Actinosynnema mirum DSM 43827 8331032 YP_003104455.1 CDS Amir_6813 NC_013093.1 7950817 7951674 D KEGG: rfr:Rfer_4028 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 7950817..7951674 Actinosynnema mirum DSM 43827 8331033 YP_003104456.1 CDS Amir_6814 NC_013093.1 7951977 7955987 D TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: SL44-1; basic proline-rich protein; cell envelope-related transcriptional attenuator 7951977..7955987 Actinosynnema mirum DSM 43827 8331034 YP_003104457.1 CDS Amir_6815 NC_013093.1 7956137 7956799 D TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: swi:Swit_3576 phosphate uptake regulator, PhoU; phosphate uptake regulator PhoU 7956137..7956799 Actinosynnema mirum DSM 43827 8331035 YP_003104458.1 CDS Amir_6816 NC_013093.1 7956860 7957660 R hypothetical protein complement(7956860..7957660) Actinosynnema mirum DSM 43827 8331036 YP_003104459.1 CDS Amir_6817 NC_013093.1 7957657 7959354 R KEGG: predicted gene, 100041170; hypothetical protein complement(7957657..7959354) Actinosynnema mirum DSM 43827 8331037 YP_003104460.1 CDS Amir_6818 NC_013093.1 7959603 7960379 R KEGG: gur:Gura_2561 phosphate ABC transporter, ATPase subunit; TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA; phosphate ABC transporter ATPase subunit complement(7959603..7960379) Actinosynnema mirum DSM 43827 8331038 YP_003104461.1 CDS Amir_6819 NC_013093.1 7960390 7961304 R TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tbd:Tbd_1138 phosphate transport system permease protein 2; phosphate ABC transporter, inner membrane subunit PstA complement(7960390..7961304) Actinosynnema mirum DSM 43827 8331039 YP_003104462.1 CDS Amir_6820 NC_013093.1 7961301 7962359 R TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bpy:Bphyt_2857 phosphate ABC transporter, inner membrane subunit PstC; phosphate ABC transporter, inner membrane subunit PstC complement(7961301..7962359) Actinosynnema mirum DSM 43827 8331040 YP_003104463.1 CDS Amir_6821 NC_013093.1 7962398 7963519 R TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: scl:sce2946 phosphate ABC transporter, substrate-binding protein PstS; phosphate ABC transporter periplasmic phosphate- binding protein complement(7962398..7963519) Actinosynnema mirum DSM 43827 8331041 YP_003104464.1 CDS Amir_6822 NC_013093.1 7963712 7964605 R TIGRFAM: mycothiol biosynthesis acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: predicted protein; mycothiol biosynthesis acetyltransferase complement(7963712..7964605) Actinosynnema mirum DSM 43827 8331042 YP_003104465.1 CDS Amir_6823 NC_013093.1 7964718 7965470 R PFAM: transcriptional regulator domain protein; KEGG: bha:BH3157 two-component response regulator involved in phosphate regulation; winged helix family two component transcriptional regulator complement(7964718..7965470) Actinosynnema mirum DSM 43827 8331043 YP_003104466.1 CDS Amir_6824 NC_013093.1 7965529 7966380 D KEGG: bha:BH1308 hypothetical protein; dipeptidylaminopeptidase/acylaminoacyl- peptidase-like protein 7965529..7966380 Actinosynnema mirum DSM 43827 8331044 YP_003104467.1 CDS Amir_6825 NC_013093.1 7966377 7967183 D KEGG: mxa:MXAN_7418 hypothetical protein; hypothetical protein 7966377..7967183 Actinosynnema mirum DSM 43827 8331045 YP_003104468.1 CDS Amir_6826 NC_013093.1 7967224 7967646 D KEGG: ank:AnaeK_1735 cytochrome C biogenesis protein transmembrane region; hypothetical protein 7967224..7967646 Actinosynnema mirum DSM 43827 8331046 YP_003104469.1 CDS Amir_6827 NC_013093.1 7967881 7968315 D KEGG: tdn:Suden_0151 CDP-alcohol phosphatidyltransferase; hypothetical protein 7967881..7968315 Actinosynnema mirum DSM 43827 8331047 YP_003104470.1 CDS Amir_6828 NC_013093.1 7968424 7969269 D PFAM: rhodanese domain protein; SMART: rhodanese domain protein; KEGG: cja:CJA_2345 rhodanese-like domain protein; rhodanese domain-containing protein 7968424..7969269 Actinosynnema mirum DSM 43827 8331048 YP_003104471.1 CDS Amir_6829 NC_013093.1 7969269 7969571 D KEGG: mxa:MXAN_0146 hypothetical protein; hypothetical protein 7969269..7969571 Actinosynnema mirum DSM 43827 8331049 YP_003104472.1 CDS Amir_6830 NC_013093.1 7969777 7969875 D hypothetical protein 7969777..7969875 Actinosynnema mirum DSM 43827 8331050 YP_003104473.1 CDS Amir_6831 NC_013093.1 7969875 7970510 D PFAM: Domain of unknown function DUF1794; KEGG: hypothetical protein; hypothetical protein 7969875..7970510 Actinosynnema mirum DSM 43827 8331051 YP_003104474.1 CDS Amir_6832 NC_013093.1 7970839 7971441 D PFAM: allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 1; KEGG: aav:Aave_3511 allophanate hydrolase subunit 2; allophanate hydrolase subunit 1 7970839..7971441 Actinosynnema mirum DSM 43827 8331052 YP_003104475.1 CDS Amir_6833 NC_013093.1 7971556 7971711 D hypothetical protein 7971556..7971711 Actinosynnema mirum DSM 43827 8331053 YP_003104476.1 CDS Amir_6834 NC_013093.1 7971708 7972565 D KEGG: aav:Aave_3511 allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; urea amidolyase-like protein 7971708..7972565 Actinosynnema mirum DSM 43827 8331054 YP_003104477.1 CDS Amir_6835 NC_013093.1 7972668 7973510 R PFAM: aminotransferase class IV; KEGG: bbr:BB0169 class IV aminotransferase; class IV aminotransferase complement(7972668..7973510) Actinosynnema mirum DSM 43827 8331055 YP_003104478.1 CDS Amir_6836 NC_013093.1 7973547 7973981 D PFAM: ferric-uptake regulator; KEGG: ank:AnaeK_2300 ferric uptake regulator, Fur family; Fur family ferric uptake regulator 7973547..7973981 Actinosynnema mirum DSM 43827 8331056 YP_003104479.1 CDS Amir_6837 NC_013093.1 7973978 7975072 D TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: mxa:MXAN_6341 glycine cleavage system T protein; folate-binding protein YgfZ 7973978..7975072 Actinosynnema mirum DSM 43827 8331057 YP_003104480.1 CDS Amir_6838 NC_013093.1 7975127 7975927 D PFAM: protein of unknown function DUF849; KEGG: rfr:Rfer_3885 hypothetical protein; 3-keto-5-aminohexanoate cleavage protein 7975127..7975927 Actinosynnema mirum DSM 43827 8331058 YP_003104481.1 CDS Amir_6839 NC_013093.1 7975988 7976563 D hypothetical protein 7975988..7976563 Actinosynnema mirum DSM 43827 8331059 YP_003104482.1 CDS Amir_6840 NC_013093.1 7976730 7977884 D PFAM: major facilitator superfamily MFS_1; KEGG: aav:Aave_4589 major facilitator superfamily MFS_1; major facilitator superfamily protein 7976730..7977884 Actinosynnema mirum DSM 43827 8331060 YP_003104483.1 CDS Amir_6841 NC_013093.1 7978110 7978991 R KEGG: bch:Bcen2424_1641 amino acid adenylation domain-containing protein; hypothetical protein complement(7978110..7978991) Actinosynnema mirum DSM 43827 8331061 YP_003104484.1 CDS Amir_6842 NC_013093.1 7979154 7979336 D hypothetical protein 7979154..7979336 Actinosynnema mirum DSM 43827 8331062 YP_003104485.1 CDS Amir_6843 NC_013093.1 7979621 7980433 D KEGG: bpm:BURPS1710b_2246 hypothetical protein; hypothetical protein 7979621..7980433 Actinosynnema mirum DSM 43827 8331063 YP_003104486.1 CDS Amir_6844 NC_013093.1 7980466 7981173 D PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; KEGG: dal:Dalk_5197 transcriptional regulator, Crp/Fnr family; Crp/Fnr family transcriptional regulator 7980466..7981173 Actinosynnema mirum DSM 43827 8331064 YP_003104487.1 CDS Amir_6845 NC_013093.1 7981470 7981847 D hypothetical protein 7981470..7981847 Actinosynnema mirum DSM 43827 8331065 YP_003104488.1 CDS Amir_6846 NC_013093.1 7981923 7983773 R PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bid:Bind_2834 thiamine pyrophosphate protein central region; thiamine pyrophosphate protein complement(7981923..7983773) Actinosynnema mirum DSM 43827 8331066 YP_003104489.1 CDS Amir_6847 NC_013093.1 7983770 7984648 R PFAM: Myo-inositol catabolism IolB domain protein; KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein; Myo-inositol catabolism IolB domain-containing protein complement(7983770..7984648) Actinosynnema mirum DSM 43827 8331067 YP_003104490.1 CDS Amir_6848 NC_013093.1 7984722 7985693 R PFAM: PfkB domain protein; KEGG: sus:Acid_1481 ribokinase-like domain- containing protein; PfkB domain-containing protein complement(7984722..7985693) Actinosynnema mirum DSM 43827 8331068 YP_003104491.1 CDS Amir_6849 NC_013093.1 7985690 7986457 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bcs:BCAN_A1367 hypothetical protein; ABC transporter complement(7985690..7986457) Actinosynnema mirum DSM 43827 8331069 YP_003104492.1 CDS Amir_6850 NC_013093.1 7986454 7987494 R PFAM: inner-membrane translocator; KEGG: acr:Acry_2317 inner-membrane translocator; Monosaccharide-transporting ATPase complement(7986454..7987494) Actinosynnema mirum DSM 43827 8331070 YP_003104493.1 CDS Amir_6851 NC_013093.1 7987500 7988507 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: acr:Acry_2318 ABC-type sugar transport system periplasmic component-like protein; LacI family transcriptional regulator complement(7987500..7988507) Actinosynnema mirum DSM 43827 8331071 YP_003104494.1 CDS Amir_6852 NC_013093.1 7988569 7989423 R PFAM: xylose isomerase; KEGG: sit:TM1040_3346 xylose isomerase-like TIM barrel; xylose isomerase complement(7988569..7989423) Actinosynnema mirum DSM 43827 8331072 YP_003104495.1 CDS Amir_6853 NC_013093.1 7989420 7990436 R PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: bbt:BBta_0488 inositol 2-dehydrogenase; inositol 2-dehydrogenase complement(7989420..7990436) Actinosynnema mirum DSM 43827 8331073 YP_003104496.1 CDS Amir_6854 NC_013093.1 7990575 7991567 D PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: pmr:PMI0088 ribose operon repressor (LacI- family transcriptional regulator); LacI family transcriptional regulator 7990575..7991567 Actinosynnema mirum DSM 43827 8331074 YP_003104497.1 CDS Amir_6855 NC_013093.1 7992407 7992820 R PFAM: Class I peptide chain release factor; KEGG: rpi:Rpic_3102 class I peptide chain release factor; peptidyl-tRNA hydrolase domain-containing protein complement(7992407..7992820) Actinosynnema mirum DSM 43827 8331075 YP_003104498.1 CDS Amir_6856 NC_013093.1 7992852 7993388 R KEGG: hypothetical protein; hypothetical protein complement(7992852..7993388) Actinosynnema mirum DSM 43827 8331076 YP_003104499.1 CDS Amir_6857 NC_013093.1 7993385 7994209 R SMART: helix-turn-helix domain protein; helix-turn-helix domain-containing protein complement(7993385..7994209) Actinosynnema mirum DSM 43827 8331077 YP_003104500.1 CDS Amir_6858 NC_013093.1 7994557 7995630 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(7994557..7995630) Actinosynnema mirum DSM 43827 8331078 YP_003104501.1 CDS Amir_6859 NC_013093.1 7995633 7997210 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(7995633..7997210) Actinosynnema mirum DSM 43827 8331079 YP_003104502.1 CDS Amir_6860 NC_013093.1 7997279 7998022 R PFAM: protein of unknown function DUF1503; hypothetical protein complement(7997279..7998022) Actinosynnema mirum DSM 43827 8331080 YP_003104503.1 CDS Amir_6861 NC_013093.1 7998232 7998546 D hypothetical protein 7998232..7998546 Actinosynnema mirum DSM 43827 8331081 YP_003104504.1 CDS Amir_6862 NC_013093.1 7998543 8000507 D PFAM: protein of unknown function DUF1023; KEGG: xca:xccb100_3697 outer membrane adhesin; hypothetical protein 7998543..8000507 Actinosynnema mirum DSM 43827 8331082 YP_003104505.1 CDS Amir_6863 NC_013093.1 8000547 8000885 R hypothetical protein complement(8000547..8000885) Actinosynnema mirum DSM 43827 8331083 YP_003104506.1 CDS Amir_6864 NC_013093.1 8000937 8001272 R hypothetical protein complement(8000937..8001272) Actinosynnema mirum DSM 43827 8331084 YP_003104507.1 CDS Amir_6865 NC_013093.1 8001309 8001686 R hypothetical protein complement(8001309..8001686) Actinosynnema mirum DSM 43827 8331085 YP_003104508.1 CDS Amir_6866 NC_013093.1 8001696 8002514 R hypothetical protein complement(8001696..8002514) Actinosynnema mirum DSM 43827 8331086 YP_003104509.1 CDS Amir_6867 NC_013093.1 8002599 8004083 R KEGG: hypothetical protein; hypothetical protein complement(8002599..8004083) Actinosynnema mirum DSM 43827 8331087 YP_003104510.1 CDS Amir_6868 NC_013093.1 8004100 8004492 R hypothetical protein complement(8004100..8004492) Actinosynnema mirum DSM 43827 8331088 YP_003104511.1 CDS Amir_6869 NC_013093.1 8004611 8005225 R hypothetical protein complement(8004611..8005225) Actinosynnema mirum DSM 43827 8331089 YP_003104512.1 CDS Amir_6870 NC_013093.1 8005343 8006374 D PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: scl:sce1528 glucose 1-dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 8005343..8006374 Actinosynnema mirum DSM 43827 8331090 YP_003104513.1 CDS Amir_6871 NC_013093.1 8006391 8008553 R KEGG: gsu:GSU0474 sensory box/GGDEF family protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase complement(8006391..8008553) Actinosynnema mirum DSM 43827 8331091 YP_003104514.1 CDS Amir_6872 NC_013093.1 8008889 8009977 D KEGG: predicted protein; hypothetical protein 8008889..8009977 Actinosynnema mirum DSM 43827 8331092 YP_003104515.1 CDS Amir_6874 NC_013093.1 8011169 8012017 D KEGG: N,O-diacetylmuramidase; PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; lysozyme 8011169..8012017 Actinosynnema mirum DSM 43827 8331094 YP_003104516.1 CDS Amir_6875 NC_013093.1 8012143 8012931 D KEGG: N,O-diacetyl muramidase; K01238; PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; lysozyme 8012143..8012931 Actinosynnema mirum DSM 43827 8331095 YP_003104517.1 CDS Amir_6876 NC_013093.1 8012996 8015254 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II complement(8012996..8015254) Actinosynnema mirum DSM 43827 8331096 YP_003104518.1 CDS Amir_6877 NC_013093.1 8015251 8015922 R TIGRFAM: phosphoribosylformylglycinamidine synthase I; KEGG: afw:Anae109_3954 phosphoribosylformylglycinamidine synthase I; phosphoribosylformylglycinamidine synthase I complement(8015251..8015922) Actinosynnema mirum DSM 43827 8331097 YP_003104519.1 CDS Amir_6878 NC_013093.1 8015919 8016158 R TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS; KEGG: eli:ELI_02445 phosphoribosylformylglycinamidine synthase small subunit; phosphoribosylformylglycinamidine synthase PurS complement(8015919..8016158) Actinosynnema mirum DSM 43827 8331098 YP_003104520.1 CDS Amir_6879 NC_013093.1 8016387 8016929 R hypothetical protein complement(8016387..8016929) Actinosynnema mirum DSM 43827 8331099 YP_003104521.1 CDS Amir_6880 NC_013093.1 8017050 8018024 D PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: bja:blr6721 reductase; NAD-dependent epimerase/dehydratase 8017050..8018024 Actinosynnema mirum DSM 43827 8331100 YP_003104522.1 CDS Amir_6881 NC_013093.1 8018150 8018773 D PFAM: beta-lactamase domain protein; KEGG: acr:Acry_1778 hydroxyacylglutathione hydrolase; beta-lactamase domain-containing protein 8018150..8018773 Actinosynnema mirum DSM 43827 8331101 YP_003104523.1 CDS Amir_6882 NC_013093.1 8018744 8019403 R KEGG: eba:ebA6939 hypothetical protein; deacetylase-like protein complement(8018744..8019403) Actinosynnema mirum DSM 43827 8331102 YP_003104524.1 CDS Amir_6883 NC_013093.1 8019558 8020445 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(8019558..8020445) Actinosynnema mirum DSM 43827 8331103 YP_003104525.1 CDS Amir_6884 NC_013093.1 8020509 8021366 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: rde:RD1_2182 amino acid ABC transporter, periplasmic-binding protein; family 3 extracellular solute-binding protein 8020509..8021366 Actinosynnema mirum DSM 43827 8331104 YP_003104526.1 CDS Amir_6885 NC_013093.1 8021363 8022223 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_2183 glutamine ABC transporter, permease protein; polar amino acid ABC transporter, inner membrane subunit 8021363..8022223 Actinosynnema mirum DSM 43827 8331105 YP_003104527.1 CDS Amir_6886 NC_013093.1 8022220 8022984 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mes:Meso_3147 ABC transporter; ABC transporter 8022220..8022984 Actinosynnema mirum DSM 43827 8331106 YP_003104528.1 CDS Amir_6887 NC_013093.1 8023065 8023544 D KEGG: similar to C25F9.2; hypothetical protein 8023065..8023544 Actinosynnema mirum DSM 43827 8331107 YP_003104529.1 CDS Amir_6888 NC_013093.1 8023612 8025042 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(8023612..8025042) Actinosynnema mirum DSM 43827 8331108 YP_003104530.1 CDS Amir_6889 NC_013093.1 8025056 8025847 R hypothetical protein complement(8025056..8025847) Actinosynnema mirum DSM 43827 8331109 YP_003104531.1 CDS Amir_6890 NC_013093.1 8025844 8026371 R TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: sus:Acid_7940 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit complement(8025844..8026371) Actinosynnema mirum DSM 43827 8331110 YP_003104532.1 CDS Amir_6891 NC_013093.1 8026418 8027008 R PFAM: regulatory protein TetR; KEGG: scl:sce1385 TetR family transcriptional regulator; TetR family transcriptional regulator complement(8026418..8027008) Actinosynnema mirum DSM 43827 8331111 YP_003104533.1 CDS Amir_6892 NC_013093.1 8027064 8027825 R KEGG: GK23094 gene product from transcript GK23094- RA; hypothetical protein complement(8027064..8027825) Actinosynnema mirum DSM 43827 8331112 YP_003104534.1 CDS Amir_6893 NC_013093.1 8027863 8028378 R TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: pca:Pcar_3124 RNA polymerase, sigma-E factor; ECF subfamily RNA polymerase sigma-24 subunit complement(8027863..8028378) Actinosynnema mirum DSM 43827 8331113 YP_003104535.1 CDS Amir_6894 NC_013093.1 8028531 8029550 D PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mxa:MXAN_1432 L-allo-threonine aldolase; aromatic amino acid beta-eliminating lyase/threonine aldolase 8028531..8029550 Actinosynnema mirum DSM 43827 8331114 YP_003104536.1 CDS Amir_6895 NC_013093.1 8029555 8030142 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: aba:Acid345_0142 HAD-superfamily hydrolase subfamily IA, variant 3; HAD superfamily hydrolase 8029555..8030142 Actinosynnema mirum DSM 43827 8331115 YP_003104537.1 CDS Amir_6896 NC_013093.1 8030251 8030403 R hypothetical protein complement(8030251..8030403) Actinosynnema mirum DSM 43827 8331116 YP_003104538.1 CDS Amir_6897 NC_013093.1 8030410 8031576 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(8030410..8031576) Actinosynnema mirum DSM 43827 8331117 YP_003104539.1 CDS Amir_6898 NC_013093.1 8031586 8032116 R hypothetical protein complement(8031586..8032116) Actinosynnema mirum DSM 43827 8331118 YP_003104540.1 CDS Amir_6899 NC_013093.1 8032236 8033012 R KEGG: ret:RHE_PE00455 sulfite reductase, beta subunit (hemoprotein) protein; hypothetical protein complement(8032236..8033012) Actinosynnema mirum DSM 43827 8331119 YP_003104541.1 CDS Amir_6900 NC_013093.1 8033009 8034322 R KEGG: Os03g0309300; hypothetical protein; hypothetical protein complement(8033009..8034322) Actinosynnema mirum DSM 43827 8331120 YP_003104542.1 CDS Amir_6901 NC_013093.1 8034335 8034937 R hypothetical protein complement(8034335..8034937) Actinosynnema mirum DSM 43827 8331121 YP_003104543.1 CDS Amir_6902 NC_013093.1 8034927 8035277 R hypothetical protein complement(8034927..8035277) Actinosynnema mirum DSM 43827 8331122 YP_003104544.1 CDS Amir_6903 NC_013093.1 8035608 8036867 R KEGG: ccs:CCNA_00299 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; phosphoribosylamine/glycine ligase complement(8035608..8036867) Actinosynnema mirum DSM 43827 8331123 YP_003104545.1 CDS Amir_6904 NC_013093.1 8036896 8037885 R TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: bpt:Bpet4159 hypothetical protein; TRAP transporter solute receptor, TAXI family complement(8036896..8037885) Actinosynnema mirum DSM 43827 8331124 YP_003104546.1 CDS Amir_6905 NC_013093.1 8037878 8039926 R TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; Citrate transporter; KEGG: bpt:Bpet4158 hypothetical protein; TRAP transporter, 4TM/12TM fusion protein complement(8037878..8039926) Actinosynnema mirum DSM 43827 8331125 YP_003104547.1 CDS Amir_6906 NC_013093.1 8040106 8041251 D PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: rce:RC1_0289 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 8040106..8041251 Actinosynnema mirum DSM 43827 8331126 YP_003104548.1 CDS Amir_6907 NC_013093.1 8041402 8042544 R PFAM: luciferase-like monooxygenase; KEGG: alkanesulfonate monooxygenase; Alkanesulfonate monooxygenase complement(8041402..8042544) Actinosynnema mirum DSM 43827 8331127 YP_003104549.1 CDS Amir_6908 NC_013093.1 8042834 8044123 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(8042834..8044123) Actinosynnema mirum DSM 43827 8331128 YP_003104550.1 CDS Amir_6909 NC_013093.1 8044218 8044889 D hypothetical protein 8044218..8044889 Actinosynnema mirum DSM 43827 8331129 YP_003104551.1 CDS Amir_6910 NC_013093.1 8045008 8045646 D KEGG: hypothetical protein; hypothetical protein 8045008..8045646 Actinosynnema mirum DSM 43827 8331130 YP_003104552.1 CDS Amir_6911 NC_013093.1 8045646 8045897 D hypothetical protein 8045646..8045897 Actinosynnema mirum DSM 43827 8331131 YP_003104553.1 CDS Amir_6912 NC_013093.1 8045952 8046938 D PFAM: glycoside hydrolase family 16; KEGG: hch:HCH_06576 hypothetical protein; glycoside hydrolase family protein 8045952..8046938 Actinosynnema mirum DSM 43827 8331132 YP_003104554.1 CDS Amir_6913 NC_013093.1 8047101 8047364 R KEGG: son:SO_3323 acetyltransferase; hypothetical protein complement(8047101..8047364) Actinosynnema mirum DSM 43827 8331133 YP_003104555.1 CDS Amir_6914 NC_013093.1 8047983 8049062 R KEGG: dac:Daci_3973 hypothetical protein; hypothetical protein complement(8047983..8049062) Actinosynnema mirum DSM 43827 8331134 YP_003104556.1 CDS Amir_6915 NC_013093.1 8049076 8049489 R hypothetical protein complement(8049076..8049489) Actinosynnema mirum DSM 43827 8331135 YP_003104557.1 CDS Amir_6916 NC_013093.1 8049496 8049591 R hypothetical protein complement(8049496..8049591) Actinosynnema mirum DSM 43827 8331136 YP_003104558.1 CDS Amir_6917 NC_013093.1 8049811 8050845 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(8049811..8050845) Actinosynnema mirum DSM 43827 8331137 YP_003104559.1 CDS Amir_6918 NC_013093.1 8050940 8051224 D PFAM: protein of unknown function DUF427; KEGG: pnu:Pnuc_1659 hypothetical protein; hypothetical protein 8050940..8051224 Actinosynnema mirum DSM 43827 8331138 YP_003104560.1 CDS Amir_6919 NC_013093.1 8051373 8052311 D PFAM: aldo/keto reductase; KEGG: ank:AnaeK_0485 aldo/keto reductase; aldo/keto reductase 8051373..8052311 Actinosynnema mirum DSM 43827 8331139 YP_003104561.1 CDS Amir_6920 NC_013093.1 8052383 8053312 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bch:Bcen2424_6846 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 8052383..8053312 Actinosynnema mirum DSM 43827 8331140 YP_003104562.1 CDS Amir_6921 NC_013093.1 8053335 8053622 R PFAM: YCII-related; KEGG: reu:Reut_B5221 YCII-related; YCII-like protein complement(8053335..8053622) Actinosynnema mirum DSM 43827 8331141 YP_003104563.1 CDS Amir_6922 NC_013093.1 8053686 8054264 D TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: mxa:MXAN_2500 RNA polymerase sigma-70 factor, ECF subfamily; ECF subfamily RNA polymerase sigma-24 subunit 8053686..8054264 Actinosynnema mirum DSM 43827 8331142 YP_003104564.1 CDS Amir_6923 NC_013093.1 8054467 8055366 D PFAM: ROK family protein; KEGG: scl:sce7667 ROK family transcriptional regulator; ROK family protein 8054467..8055366 Actinosynnema mirum DSM 43827 8331143 YP_003104565.1 CDS Amir_6924 NC_013093.1 8055363 8056520 D KEGG: smt:Smal_3421 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase 8055363..8056520 Actinosynnema mirum DSM 43827 8331144 YP_003104566.1 CDS Amir_6925 NC_013093.1 8056549 8057331 D KEGG: hypothetical protein; hypothetical protein 8056549..8057331 Actinosynnema mirum DSM 43827 8331145 YP_003104567.1 CDS Amir_6926 NC_013093.1 8057341 8058090 D PFAM: hypothetical protein; KEGG: pfo:Pfl01_4994 hypothetical protein; hypothetical protein 8057341..8058090 Actinosynnema mirum DSM 43827 8331146 YP_003104568.1 CDS Amir_6927 NC_013093.1 8058097 8059482 R PFAM: FAD linked oxidase domain protein; KEGG: scl:sce0752 glycolate oxidase; FAD linked oxidase domain-containing protein complement(8058097..8059482) Actinosynnema mirum DSM 43827 8331147 YP_003104569.1 CDS Amir_6928 NC_013093.1 8059601 8060275 D PFAM: hypothetical protein; KEGG: plu:plu3172 hypothetical protein; hypothetical protein 8059601..8060275 Actinosynnema mirum DSM 43827 8331148 YP_003104570.1 CDS Amir_6929 NC_013093.1 8060306 8060941 R KEGG: dac:Daci_0781 hypothetical protein; hypothetical protein complement(8060306..8060941) Actinosynnema mirum DSM 43827 8331149 YP_003104571.1 CDS Amir_6930 NC_013093.1 8060923 8061864 R PFAM: PfkB domain protein; KEGG: sfu:Sfum_3386 PfkB domain protein; PfkB domain-containing protein complement(8060923..8061864) Actinosynnema mirum DSM 43827 8331150 YP_003104572.1 CDS Amir_6931 NC_013093.1 8061943 8062890 D PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: acr:Acry_0501 periplasmic binding protein/LacI transcriptional regulator; LacI family transcriptional regulator 8061943..8062890 Actinosynnema mirum DSM 43827 8331151 YP_003104573.1 CDS Amir_6932 NC_013093.1 8062919 8064034 R PFAM: glycoside hydrolase family 76; KEGG: hypothetical protein; glycoside hydrolase family protein complement(8062919..8064034) Actinosynnema mirum DSM 43827 8331152 YP_003104574.1 CDS Amir_6933 NC_013093.1 8064053 8064760 R PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: azo:azo1893 RNA methyltransferase; tRNA/rRNA methyltransferase SpoU complement(8064053..8064760) Actinosynnema mirum DSM 43827 8331153 YP_003104575.1 CDS Amir_6934 NC_013093.1 8064832 8065221 R KEGG: eba:ebB138 hypothetical protein; hypothetical protein complement(8064832..8065221) Actinosynnema mirum DSM 43827 8331154 YP_003104576.1 CDS Amir_6935 NC_013093.1 8065297 8066007 R hypothetical protein complement(8065297..8066007) Actinosynnema mirum DSM 43827 8331155 YP_003104577.1 CDS pyrE NC_013093.1 8066009 8066563 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(8066009..8066563) Actinosynnema mirum DSM 43827 8331156 YP_003104578.1 CDS Amir_6937 NC_013093.1 8066630 8067184 D hypothetical protein 8066630..8067184 Actinosynnema mirum DSM 43827 8331157 YP_003104579.1 CDS Amir_6938 NC_013093.1 8067217 8067621 R hypothetical protein complement(8067217..8067621) Actinosynnema mirum DSM 43827 8331158 YP_003104580.1 CDS Amir_6939 NC_013093.1 8067618 8068526 R hypothetical protein complement(8067618..8068526) Actinosynnema mirum DSM 43827 8331159 YP_003104581.1 CDS Amir_6940 NC_013093.1 8068523 8068876 R hypothetical protein complement(8068523..8068876) Actinosynnema mirum DSM 43827 8331160 YP_003104582.1 CDS Amir_6941 NC_013093.1 8069021 8069800 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: azc:AZC_1379 short-chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(8069021..8069800) Actinosynnema mirum DSM 43827 8331161 YP_003104583.1 CDS Amir_6942 NC_013093.1 8069797 8070501 R hypothetical protein complement(8069797..8070501) Actinosynnema mirum DSM 43827 8331162 YP_003104584.1 CDS Amir_6943 NC_013093.1 8070630 8073212 R KEGG: ank:AnaeK_0413 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA; ATPase AAA; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA; ATP-dependent chaperone ClpB complement(8070630..8073212) Actinosynnema mirum DSM 43827 8331163 YP_003104585.1 CDS Amir_6944 NC_013093.1 8073413 8073808 D KEGG: rle:RL3033 hypothetical protein; hypothetical protein 8073413..8073808 Actinosynnema mirum DSM 43827 8331164 YP_003104586.1 CDS Amir_6945 NC_013093.1 8074275 8075378 D PFAM: oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; globin; KEGG: afr:AFE_0860 iron-sulfur cluster-binding protein/oxidoreductase, FAD/NAD-binding; oxidoreductase FAD-binding domain-containing protein 8074275..8075378 Actinosynnema mirum DSM 43827 8331165 YP_003104587.1 CDS Amir_6946 NC_013093.1 8075838 8076269 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: cjj:CJJ81176_1244 MerR family transcriptional regulator; MerR family transcriptional regulator complement(8075838..8076269) Actinosynnema mirum DSM 43827 8331166 YP_003104588.1 CDS Amir_6947 NC_013093.1 8076266 8077462 R KEGG: pag:PLES_51451 DnaJ protein; TIGRFAM: chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; chaperone protein DnaJ complement(8076266..8077462) Actinosynnema mirum DSM 43827 8331167 YP_003104589.1 CDS Amir_6948 NC_013093.1 8077483 8078136 R PFAM: GrpE protein; KEGG: dvm:DvMF_1194 GrpE protein; GrpE protein complement(8077483..8078136) Actinosynnema mirum DSM 43827 8331168 YP_003104590.1 CDS dnaK NC_013093.1 8078133 8079992 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(8078133..8079992) Actinosynnema mirum DSM 43827 8331169 YP_003104591.1 CDS Amir_6950 NC_013093.1 8080207 8081013 R KEGG: aba:Acid345_3530 hypothetical protein; hypothetical protein complement(8080207..8081013) Actinosynnema mirum DSM 43827 8331170 YP_003104592.1 CDS Amir_6951 NC_013093.1 8081179 8081754 R hypothetical protein complement(8081179..8081754) Actinosynnema mirum DSM 43827 8331171 YP_003104593.1 CDS Amir_6952 NC_013093.1 8081915 8082244 R PFAM: small multidrug resistance protein; KEGG: oan:Oant_2259 small multidrug resistance protein; small multidrug resistance protein complement(8081915..8082244) Actinosynnema mirum DSM 43827 8331172 YP_003104594.1 CDS Amir_6953 NC_013093.1 8082402 8084678 D PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ade:Adeh_0008 hypothetical protein; hypothetical protein 8082402..8084678 Actinosynnema mirum DSM 43827 8331173 YP_003104595.1 CDS Amir_6954 NC_013093.1 8084757 8085137 R PFAM: membrane protein of unknown function; KEGG: bmv:BMASAVP1_A3416 hypothetical protein; hypothetical protein complement(8084757..8085137) Actinosynnema mirum DSM 43827 8331174 YP_003104596.1 CDS Amir_6955 NC_013093.1 8085172 8086362 R KEGG: dsh:Dshi_3592 Cna B domain-containing protein; hypothetical protein complement(8085172..8086362) Actinosynnema mirum DSM 43827 8331175 YP_003104597.1 CDS Amir_6956 NC_013093.1 8086602 8087444 R KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein complement(8086602..8087444) Actinosynnema mirum DSM 43827 8331176 YP_003104598.1 CDS Amir_6957 NC_013093.1 8087622 8088740 R KEGG: gme:Gmet_2043 hypothetical protein; hypothetical protein complement(8087622..8088740) Actinosynnema mirum DSM 43827 8331177 YP_003104599.1 CDS Amir_6958 NC_013093.1 8088946 8090061 R TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: dsh:Dshi_3592 Cna B domain-containing protein; LPXTG-motif cell wall anchor domain-containing protein complement(8088946..8090061) Actinosynnema mirum DSM 43827 8331178 YP_003104600.1 CDS dcd NC_013093.1 8090391 8091026 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(8090391..8091026) Actinosynnema mirum DSM 43827 8331179 YP_003104601.1 CDS Amir_6960 NC_013093.1 8091736 8092320 D KEGG: similar to involucrin repeat protein; hypothetical protein 8091736..8092320 Actinosynnema mirum DSM 43827 8331181 YP_003104602.1 CDS Amir_6961 NC_013093.1 8092372 8093973 R PFAM: Na+/solute symporter; KEGG: vsp:VS_1257 sodium/glucose cotransporter; Na+/solute symporter complement(8092372..8093973) Actinosynnema mirum DSM 43827 8331182 YP_003104603.1 CDS Amir_6962 NC_013093.1 8094222 8094926 D PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; KEGG: xcv:XCV2187 two-component system LuxR family regulatory protein; LuxR family transcriptional regulator 8094222..8094926 Actinosynnema mirum DSM 43827 8331183 YP_003104604.1 CDS Amir_6963 NC_013093.1 8095175 8097013 D PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mxa:MXAN_0422 acyl-CoA dehydrogenase; acyl-CoA dehydrogenase domain-containing protein 8095175..8097013 Actinosynnema mirum DSM 43827 8331184 YP_003104605.1 CDS Amir_6964 NC_013093.1 8097110 8097853 R PFAM: protein of unknown function DUF1206; KEGG: afw:Anae109_1905 hypothetical protein; hypothetical protein complement(8097110..8097853) Actinosynnema mirum DSM 43827 8331185 YP_003104606.1 CDS Amir_6965 NC_013093.1 8097981 8100659 R PFAM: VanW family protein; KEGG: bcb:BCB4264_A0642 vancomycin B-type resistance protein VanW; VanW family protein complement(8097981..8100659) Actinosynnema mirum DSM 43827 8331186 YP_003104607.1 CDS Amir_6966 NC_013093.1 8100739 8101059 R PFAM: chaperonin Cpn10; KEGG: noc:Noc_2922 co-chaperonin GroES; chaperonin Cpn10 complement(8100739..8101059) Actinosynnema mirum DSM 43827 8331187 YP_003104608.1 CDS Amir_6967 NC_013093.1 8101121 8102959 R PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; NHL repeat containing protein; Redoxin domain protein; KEGG: haloacid dehalogenase-like hydrolase family protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen complement(8101121..8102959) Actinosynnema mirum DSM 43827 8331188 YP_003104609.1 CDS Amir_6968 NC_013093.1 8103057 8103425 R hypothetical protein complement(8103057..8103425) Actinosynnema mirum DSM 43827 8331189 YP_003104610.1 CDS Amir_6969 NC_013093.1 8103886 8104032 R hypothetical protein complement(8103886..8104032) Actinosynnema mirum DSM 43827 8331190 YP_003104611.1 CDS Amir_6970 NC_013093.1 8104288 8104953 D PFAM: protein of unknown function DUF541; KEGG: bra:BRADO0381 hypothetical protein; hypothetical protein 8104288..8104953 Actinosynnema mirum DSM 43827 8331191 YP_003104612.1 CDS Amir_6971 NC_013093.1 8105070 8106293 R PFAM: OmpA/MotB domain protein; KEGG: dsh:Dshi_3025 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein complement(8105070..8106293) Actinosynnema mirum DSM 43827 8331192 YP_003104613.1 CDS Amir_6972 NC_013093.1 8106378 8107643 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(8106378..8107643) Actinosynnema mirum DSM 43827 8331193 YP_003104614.1 CDS fabG NC_013093.1 8107725 8109197 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 8107725..8109197 Actinosynnema mirum DSM 43827 8331194 YP_003104615.1 CDS Amir_6974 NC_013093.1 8109197 8110000 D PFAM: MaoC domain protein dehydratase; KEGG: abo:ABO_1719 MaoC like domain-containing protein; MaoC domain-containing protein dehydratase 8109197..8110000 Actinosynnema mirum DSM 43827 8331195 YP_003104616.1 CDS Amir_6977 NC_013093.1 8111546 8112760 R PFAM: acyl-CoA dehydrogenase domain protein; acyl- CoA dehydrogenase type 2 domain; KEGG: afw:Anae109_2163 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein complement(8111546..8112760) Actinosynnema mirum DSM 43827 8331198 YP_003104617.1 CDS Amir_6978 NC_013093.1 8112762 8113400 R KEGG: hsdl2; Hydroxysteroid dehydrogenase-like protein 2; hypothetical protein complement(8112762..8113400) Actinosynnema mirum DSM 43827 8331199 YP_003104618.1 CDS Amir_6979 NC_013093.1 8113502 8114164 D PFAM: regulatory protein TetR; KEGG: bav:BAV3196 TetR-family trasncriptional regulator; TetR family transcriptional regulator 8113502..8114164 Actinosynnema mirum DSM 43827 8331200 YP_003104619.1 CDS Amir_6980 NC_013093.1 8114416 8115315 R PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: sal:Sala_2443 MerR family transcriptional regulator; MerR family transcriptional regulator complement(8114416..8115315) Actinosynnema mirum DSM 43827 8331201 YP_003104620.1 CDS Amir_6981 NC_013093.1 8115420 8116772 R PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bha:BH2653 branched-chain alpha-keto acid dehydrogenase subunit E2; hypothetical protein complement(8115420..8116772) Actinosynnema mirum DSM 43827 8331202 YP_003104621.1 CDS Amir_6982 NC_013093.1 8116783 8117805 R PFAM: transketolase; transketolase; KEGG: afw:Anae109_1994 transketolase; transketolase complement(8116783..8117805) Actinosynnema mirum DSM 43827 8331203 YP_003104622.1 CDS Amir_6983 NC_013093.1 8117805 8118998 R KEGG: gme:Gmet_2509 dehydrogenase, E1 component; TIGRFAM: pyruvate dehydrogenase (acetyl- transferring) E1 component, alpha subunit; PFAM: dehydrogenase E1 component; pyruvate dehydrogenase E1 component subunit alpha complement(8117805..8118998) Actinosynnema mirum DSM 43827 8331204 YP_003104623.1 CDS Amir_6984 NC_013093.1 8119338 8120747 D PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: xca:xccb100_1378 hypothetical protein; peptidase M20 8119338..8120747 Actinosynnema mirum DSM 43827 8331205 YP_003104624.1 CDS Amir_6985 NC_013093.1 8120931 8123618 D KEGG: sus:Acid_7132 hypothetical protein; hypothetical protein 8120931..8123618 Actinosynnema mirum DSM 43827 8331206 YP_003104625.1 CDS Amir_6986 NC_013093.1 8123790 8124605 D PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: acr:Acry_0683 extracellular solute-binding protein; family 3 extracellular solute-binding protein 8123790..8124605 Actinosynnema mirum DSM 43827 8331207 YP_003104626.1 CDS Amir_6987 NC_013093.1 8124672 8125508 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: acr:Acry_0684 polar amino acid ABC transporter, inner membrane subunit; polar amino acid ABC transporter, inner membrane subunit 8124672..8125508 Actinosynnema mirum DSM 43827 8331208 YP_003104627.1 CDS Amir_6988 NC_013093.1 8125505 8126302 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: acr:Acry_0685 ABC transporter; ABC transporter 8125505..8126302 Actinosynnema mirum DSM 43827 8331209 YP_003104628.1 CDS Amir_6989 NC_013093.1 8126304 8128442 D KEGG: rce:RC1_0389 hypothetical protein; hypothetical protein 8126304..8128442 Actinosynnema mirum DSM 43827 8331210 YP_003104629.1 CDS Amir_6990 NC_013093.1 8128546 8129391 D KEGG: Os02g0127100; hypothetical protein; hypothetical protein 8128546..8129391 Actinosynnema mirum DSM 43827 8331211 YP_003104630.1 CDS Amir_6991 NC_013093.1 8129388 8130407 D hypothetical protein 8129388..8130407 Actinosynnema mirum DSM 43827 8331212 YP_003104631.1 CDS Amir_6992 NC_013093.1 8130404 8131534 D KEGG: mxa:MXAN_1088 serine-threonine protein kinase; hypothetical protein 8130404..8131534 Actinosynnema mirum DSM 43827 8331213 YP_003104632.1 CDS Amir_6993 NC_013093.1 8131665 8132345 D KEGG: GL23092 gene product from transcript GL23092- RA; hypothetical protein 8131665..8132345 Actinosynnema mirum DSM 43827 8331214 YP_003104633.1 CDS Amir_6994 NC_013093.1 8133054 8134865 D catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 8133054..8134865 Actinosynnema mirum DSM 43827 8331215 YP_003104634.1 CDS Amir_6995 NC_013093.1 8135361 8136191 R KEGG: hypothetical protein; hypothetical protein complement(8135361..8136191) Actinosynnema mirum DSM 43827 8331216 YP_003104635.1 CDS Amir_6996 NC_013093.1 8136356 8137858 R KEGG: pap:PSPA7_0052 hypothetical protein; hypothetical protein complement(8136356..8137858) Actinosynnema mirum DSM 43827 8331217 YP_003104636.1 CDS Amir_6997 NC_013093.1 8138036 8138734 D PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; KEGG: reu:Reut_A2447 GntR family transcriptional regulator; GntR family transcriptional regulator 8138036..8138734 Actinosynnema mirum DSM 43827 8331218 YP_003104637.1 CDS Amir_6998 NC_013093.1 8138931 8139209 D KEGG: bur:Bcep18194_A5681 hypothetical protein; hypothetical protein 8138931..8139209 Actinosynnema mirum DSM 43827 8331219 YP_003104638.1 CDS Amir_6999 NC_013093.1 8139206 8140855 D PFAM: Na+/solute symporter; KEGG: bvi:Bcep1808_2427 Na+/solute symporter; Na+/solute symporter 8139206..8140855 Actinosynnema mirum DSM 43827 8331220 YP_003104639.1 CDS Amir_7000 NC_013093.1 8140833 8141759 R PFAM: ROK family protein; KEGG: mlo:mlr7234 glucose kinase; ROK family protein complement(8140833..8141759) Actinosynnema mirum DSM 43827 8331221 YP_003104640.1 CDS Amir_7002 NC_013093.1 8142133 8142999 D PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; XRE family transcriptional regulator 8142133..8142999 Actinosynnema mirum DSM 43827 8331223 YP_003104641.1 CDS Amir_7003 NC_013093.1 8143000 8143254 D PFAM: protein of unknown function DUF397; hypothetical protein 8143000..8143254 Actinosynnema mirum DSM 43827 8331224 YP_003104642.1 CDS Amir_7004 NC_013093.1 8143229 8145061 R PFAM: GTP-binding protein HSR1-related; KEGG: mca:MCA1193 hypothetical protein; HSR1-like GTP-binding protein complement(8143229..8145061) Actinosynnema mirum DSM 43827 8331225 YP_003104643.1 CDS Amir_7005 NC_013093.1 8145058 8145432 R KEGG: mno:Mnod_1146 GrpE protein; hypothetical protein complement(8145058..8145432) Actinosynnema mirum DSM 43827 8331226 YP_003104644.1 CDS Amir_7006 NC_013093.1 8145429 8146922 R KEGG: cha:CHAB381_0860 GTP-binding protein; hypothetical protein complement(8145429..8146922) Actinosynnema mirum DSM 43827 8331227 YP_003104645.1 CDS Amir_7007 NC_013093.1 8147162 8147929 D KEGG: Sfrs15; splicing factor, arginine/serine-rich 15; hypothetical protein 8147162..8147929 Actinosynnema mirum DSM 43827 8331228 YP_003104646.1 CDS Amir_7008 NC_013093.1 8148082 8149290 D PFAM: histidine kinase dimerization and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase 8148082..8149290 Actinosynnema mirum DSM 43827 8331229 YP_003104647.1 CDS Amir_7009 NC_013093.1 8149340 8149996 D PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: scl:sce5431 two-component system response regulator; LuxR family transcriptional regulator 8149340..8149996 Actinosynnema mirum DSM 43827 8331230 YP_003104648.1 CDS Amir_7010 NC_013093.1 8150042 8150950 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_3578 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(8150042..8150950) Actinosynnema mirum DSM 43827 8331231 YP_003104649.1 CDS Amir_7011 NC_013093.1 8151025 8151597 R PFAM: regulatory protein TetR; KEGG: eum:ECUMN_4825 regulator of macrolide 2'- phosphotransferase I; TetR family transcriptional regulator complement(8151025..8151597) Actinosynnema mirum DSM 43827 8331232 YP_003104650.1 CDS Amir_7012 NC_013093.1 8151683 8152468 D TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: mno:Mnod_7133 Cof-like hydrolase; HAD superfamily hydrolase 8151683..8152468 Actinosynnema mirum DSM 43827 8331233 YP_003104651.1 CDS Amir_7013 NC_013093.1 8152577 8153338 D KEGG: hypothetical protein; hypothetical protein 8152577..8153338 Actinosynnema mirum DSM 43827 8331234 YP_003104652.1 CDS Amir_7014 NC_013093.1 8153575 8154741 R PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerization and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: scl:sce5432 two-component system sensor kinase; histidine kinase complement(8153575..8154741) Actinosynnema mirum DSM 43827 8331235 YP_003104653.1 CDS Amir_7015 NC_013093.1 8154911 8155009 D hypothetical protein 8154911..8155009 Actinosynnema mirum DSM 43827 8331236 YP_003104654.1 CDS Amir_7016 NC_013093.1 8155091 8155810 R KEGG: tgr:Tgr7_3237 tRNA (guanine-N(7)-)- methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; tRNA (guanine-N(7)-)-methyltransferase complement(8155091..8155810) Actinosynnema mirum DSM 43827 8331237 YP_003104655.1 CDS Amir_7017 NC_013093.1 8155833 8156465 R hypothetical protein complement(8155833..8156465) Actinosynnema mirum DSM 43827 8331238 YP_003104656.1 CDS Amir_7018 NC_013093.1 8156699 8158042 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: hypothetical protein; peptidase S8/S53 subtilisin kexin sedolisin 8156699..8158042 Actinosynnema mirum DSM 43827 8331239 YP_003104657.1 CDS Amir_7019 NC_013093.1 8158201 8158974 R KEGG: esa:ESA_01546 hypothetical protein; hypothetical protein complement(8158201..8158974) Actinosynnema mirum DSM 43827 8331240 YP_003104658.1 CDS Amir_7020 NC_013093.1 8158971 8159891 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bha:BH0445 ABC transporter ATP-binding protein; ABC transporter complement(8158971..8159891) Actinosynnema mirum DSM 43827 8331241 YP_003104659.1 CDS Amir_7021 NC_013093.1 8159888 8160004 R hypothetical protein complement(8159888..8160004) Actinosynnema mirum DSM 43827 8331242 YP_003104660.1 CDS Amir_7022 NC_013093.1 8160106 8160537 D PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: bja:blr4240 hypothetical protein; pyridoxamine 5'-phosphate oxidase-like FMN- binding protein 8160106..8160537 Actinosynnema mirum DSM 43827 8331243 YP_003104661.1 CDS Amir_7023 NC_013093.1 8160638 8160994 R hypothetical protein complement(8160638..8160994) Actinosynnema mirum DSM 43827 8331244 YP_003104662.1 CDS Amir_7024 NC_013093.1 8161086 8162390 D PFAM: amidohydrolase; adenosine/AMP deaminase; Amidohydrolase 3; KEGG: tmz:Tmz1t_1721 amidohydrolase; amidohydrolase 8161086..8162390 Actinosynnema mirum DSM 43827 8331245 YP_003104663.1 CDS Amir_7025 NC_013093.1 8162471 8163160 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rce:RC1_3985 oxidoreductase, short chain dehydrogenase; short chain dehydrogenase complement(8162471..8163160) Actinosynnema mirum DSM 43827 8331246 YP_003104664.1 CDS Amir_7026 NC_013093.1 8163343 8165433 R PFAM: protein of unknown function DUF839; KEGG: mes:Meso_0954 twin-arginine translocation pathway signal; hypothetical protein complement(8163343..8165433) Actinosynnema mirum DSM 43827 8331247 YP_003104665.1 CDS Amir_7027 NC_013093.1 8165608 8167641 R PFAM: protein of unknown function DUF839; KEGG: noc:Noc_2144 hypothetical protein; hypothetical protein complement(8165608..8167641) Actinosynnema mirum DSM 43827 8331248 YP_003104666.1 CDS Amir_7028 NC_013093.1 8167702 8168862 R PFAM: major facilitator superfamily MFS_1; KEGG: rpc:RPC_3634 major facilitator transporter; major facilitator superfamily protein complement(8167702..8168862) Actinosynnema mirum DSM 43827 8331249 YP_003104667.1 CDS Amir_7029 NC_013093.1 8168928 8169569 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: vei:Veis_2048 HAD-superfamily hydrolase, subfamily IA, variant 3; HAD superfamily hydrolase 8168928..8169569 Actinosynnema mirum DSM 43827 8331250 YP_003104668.1 CDS Amir_7030 NC_013093.1 8169686 8170414 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pna:Pnap_2712 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 8169686..8170414 Actinosynnema mirum DSM 43827 8331251 YP_003104669.1 CDS Amir_7031 NC_013093.1 8170546 8171637 R TIGRFAM: inositol 1-phosphate synthase; PFAM: Myo-inositol-1-phosphate synthase; Myo- inositol-1-phosphate synthase GAPDH domain protein; KEGG: sme:SM_b20249 myo-inositol-1- phosphate synthase; inositol 1-phosphate synthase complement(8170546..8171637) Actinosynnema mirum DSM 43827 8331252 YP_003104670.1 CDS Amir_7032 NC_013093.1 8171667 8172212 R PFAM: transcriptional regulator PadR family protein; KEGG: dal:Dalk_2104 transcriptional regulator, PadR- like family; PadR family transcriptional regulator complement(8171667..8172212) Actinosynnema mirum DSM 43827 8331253 YP_003104671.1 CDS Amir_7033 NC_013093.1 8172378 8172782 D hypothetical protein 8172378..8172782 Actinosynnema mirum DSM 43827 8331254 YP_003104672.1 CDS Amir_7034 NC_013093.1 8173119 8175635 D PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: bsu:BSU37510 hypothetical protein; glycosyl transferase family protein 8173119..8175635 Actinosynnema mirum DSM 43827 8331255 YP_003104673.1 CDS Amir_7035 NC_013093.1 8175765 8177324 D KEGG: ade:Adeh_0166 integral membrane protein-like; integral membrane protein 8175765..8177324 Actinosynnema mirum DSM 43827 8331256 YP_003104674.1 CDS Amir_7036 NC_013093.1 8177399 8178796 R KEGG: afw:Anae109_0175 integral membrane protein- like protein; integral membrane protein complement(8177399..8178796) Actinosynnema mirum DSM 43827 8331257 YP_003104675.1 CDS Amir_7037 NC_013093.1 8178793 8179563 R Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV complement(8178793..8179563) Actinosynnema mirum DSM 43827 8331258 YP_003104676.1 CDS Amir_7038 NC_013093.1 8179740 8180720 D KEGG: Taf4a; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor; K03129 transcription initiation factor TFIID subunit D3; TAF4A RNA polymerase II 8179740..8180720 Actinosynnema mirum DSM 43827 8331259 YP_003104677.1 CDS Amir_7039 NC_013093.1 8180975 8181331 D TIGRFAM: ribosomal protein S6; PFAM: ribosomal protein S6; KEGG: bcy:Bcer98_4014 30S ribosomal protein S6; 30S ribosomal protein S6 8180975..8181331 Actinosynnema mirum DSM 43827 8331260 YP_003104678.1 CDS Amir_7040 NC_013093.1 8181345 8181851 D TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bsu:BSU40900 single-strand DNA-binding protein; single-strand binding protein 8181345..8181851 Actinosynnema mirum DSM 43827 8331261 YP_003104679.1 CDS rpsR NC_013093.1 8181903 8182142 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 8181903..8182142 Actinosynnema mirum DSM 43827 8331262 YP_003104680.1 CDS Amir_7042 NC_013093.1 8182162 8182617 D TIGRFAM: ribosomal protein L9; PFAM: ribosomal protein L9; KEGG: bcb:BCB4264_A5596 ribosomal protein L9; 50S ribosomal protein L9 8182162..8182617 Actinosynnema mirum DSM 43827 8331263 YP_003104681.1 CDS Amir_7043 NC_013093.1 8183036 8185354 D TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; KEGG: bcm:Bcenmc03_1893 DnaB domain-containing protein; replicative DNA helicase 8183036..8185354 Actinosynnema mirum DSM 43827 8331264 YP_003104682.1 CDS Amir_7044 NC_013093.1 8186032 8186406 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rru:Rru_A2907 anti-sigma-factor antagonist domain-containing protein; anti-sigma-factor antagonist 8186032..8186406 Actinosynnema mirum DSM 43827 8331265 YP_003104683.1 CDS Amir_7045 NC_013093.1 8186431 8187183 R PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: nar:Saro_2963 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR complement(8186431..8187183) Actinosynnema mirum DSM 43827 8331266 YP_003104684.1 CDS Amir_7046 NC_013093.1 8187270 8188106 D SMART: helix-turn-helix domain protein; KEGG: acr:Acry_0313 XRE family transcriptional regulator; helix-turn-helix domain-containing protein 8187270..8188106 Actinosynnema mirum DSM 43827 8331267 YP_003104685.1 CDS Amir_7047 NC_013093.1 8188123 8189271 D PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: rme:Rmet_3922 DNA polymerase III, epsilon subunit; exonuclease RNase T and DNA polymerase III 8188123..8189271 Actinosynnema mirum DSM 43827 8331268 YP_003104686.1 CDS Amir_7048 NC_013093.1 8189373 8190155 D KEGG: pen:PSEEN1648 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase 8189373..8190155 Actinosynnema mirum DSM 43827 8331269 YP_003104687.1 CDS Amir_7049 NC_013093.1 8190298 8193360 R KEGG: bch:Bcen2424_6767 outer membrane autotransporter; hypothetical protein complement(8190298..8193360) Actinosynnema mirum DSM 43827 8331270 YP_003104688.1 CDS Amir_7050 NC_013093.1 8193537 8194379 R KEGG: GK21216 gene product from transcript GK21216- RA; hypothetical protein complement(8193537..8194379) Actinosynnema mirum DSM 43827 8331271 YP_003104689.1 CDS Amir_7051 NC_013093.1 8194664 8197108 R KEGG: rce:RC1_0389 hypothetical protein; hypothetical protein complement(8194664..8197108) Actinosynnema mirum DSM 43827 8331272 YP_003104690.1 CDS Amir_7052 NC_013093.1 8197240 8198448 D PFAM: protein of unknown function UPF0118; KEGG: mxa:MXAN_7270 hypothetical protein; hypothetical protein 8197240..8198448 Actinosynnema mirum DSM 43827 8331273 YP_003104691.1 CDS Amir_7053 NC_013093.1 8198464 8199663 R KEGG: pca:Pcar_1107 two component signal transduction response regulator; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; diguanylate cyclase complement(8198464..8199663) Actinosynnema mirum DSM 43827 8331274 YP_003104692.1 CDS Amir_7054 NC_013093.1 8199826 8200971 D PFAM: ATP-binding region ATPase domain protein; KEGG: bpl:BURPS1106A_1352 membrane sensor histidine kinase; signal transduction histidine kinase 8199826..8200971 Actinosynnema mirum DSM 43827 8331275 YP_003104693.1 CDS Amir_7055 NC_013093.1 8200968 8201627 D PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: reh:H16_B2334 response regulator, NarL-family; LuxR family transcriptional regulator 8200968..8201627 Actinosynnema mirum DSM 43827 8331276 YP_003104694.1 CDS Amir_7056 NC_013093.1 8201666 8201773 R hypothetical protein complement(8201666..8201773) Actinosynnema mirum DSM 43827 8331277 YP_003104695.1 CDS Amir_7058 NC_013093.1 8202333 8202446 D hypothetical protein 8202333..8202446 Actinosynnema mirum DSM 43827 8331279 YP_003104696.1 CDS Amir_7059 NC_013093.1 8202469 8203356 D hypothetical protein 8202469..8203356 Actinosynnema mirum DSM 43827 8331280 YP_003104697.1 CDS Amir_7060 NC_013093.1 8203357 8203992 D hypothetical protein 8203357..8203992 Actinosynnema mirum DSM 43827 8331281 YP_003104698.1 CDS Amir_7061 NC_013093.1 8203995 8204597 D PFAM: protein of unknown function DUF1707; KEGG: swp:swp_3997 hypothetical protein; hypothetical protein 8203995..8204597 Actinosynnema mirum DSM 43827 8331282 YP_003104699.1 CDS Amir_7062 NC_013093.1 8204631 8206169 D PFAM: NmrA family protein; NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; dTDP-4- dehydrorhamnose reductase; KEGG: dvl:Dvul_2879 NAD-dependent epimerase/dehydratase; NmrA family protein 8204631..8206169 Actinosynnema mirum DSM 43827 8331283 YP_003104700.1 CDS tdh NC_013093.1 8206231 8207265 D converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 8206231..8207265 Actinosynnema mirum DSM 43827 8331284 YP_003104701.1 CDS Amir_7064 NC_013093.1 8207265 8208449 D catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 8207265..8208449 Actinosynnema mirum DSM 43827 8331285 YP_003104702.1 CDS Amir_7065 NC_013093.1 8208534 8209418 D PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pmy:Pmen_4546 LysR family transcriptional regulator; LysR family transcriptional regulator 8208534..8209418 Actinosynnema mirum DSM 43827 8331286 YP_003104703.1 CDS Amir_7066 NC_013093.1 8209394 8209726 R hypothetical protein complement(8209394..8209726) Actinosynnema mirum DSM 43827 8331287 YP_003104704.1 CDS Amir_7067 NC_013093.1 8210320 8211402 R KEGG: sfu:Sfum_3180 hypothetical protein; hypothetical protein complement(8210320..8211402) Actinosynnema mirum DSM 43827 8331288 YP_003104705.1 CDS Amir_7068 NC_013093.1 8211547 8211978 R hypothetical protein complement(8211547..8211978) Actinosynnema mirum DSM 43827 8331289 YP_003104706.1 CDS Amir_7069 NC_013093.1 8211993 8213624 R TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: scl:sce2489 fructose-specific MTP; phosphoenolpyruvate-protein phosphotransferase complement(8211993..8213624) Actinosynnema mirum DSM 43827 8331290 YP_003104707.1 CDS Amir_7070 NC_013093.1 8213696 8214547 R PFAM: PfkB domain protein; KEGG: bmj:BMULJ_01615 ribokinase; PfkB domain-containing protein complement(8213696..8214547) Actinosynnema mirum DSM 43827 8331291 YP_003104708.1 CDS Amir_7071 NC_013093.1 8214662 8216581 D KEGG: mpo:Mpop_4712 hypothetical protein; hypothetical protein 8214662..8216581 Actinosynnema mirum DSM 43827 8331292 YP_003104709.1 CDS Amir_7072 NC_013093.1 8216872 8219004 R PFAM: MMPL domain protein; KEGG: bcr:BCAH187_A1444 transporter; MMPL domain-containing protein complement(8216872..8219004) Actinosynnema mirum DSM 43827 8331293 YP_003104710.1 CDS Amir_7073 NC_013093.1 8219133 8219879 D PFAM: regulatory protein TetR; KEGG: mes:Meso_0701 transcriptional regulator, TetR family; TetR family transcriptional regulator 8219133..8219879 Actinosynnema mirum DSM 43827 8331294 YP_003104711.1 CDS leuS NC_013093.1 8219961 8222765 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(8219961..8222765) Actinosynnema mirum DSM 43827 8331295 YP_003104712.1 CDS Amir_7075 NC_013093.1 8222941 8223471 D KEGG: hypothetical protein; hypothetical protein 8222941..8223471 Actinosynnema mirum DSM 43827 8331296 YP_003104713.1 CDS Amir_7076 NC_013093.1 8223494 8224075 R PFAM: protein of unknown function DUF179; KEGG: aeh:Mlg_0349 hypothetical protein; hypothetical protein complement(8223494..8224075) Actinosynnema mirum DSM 43827 8331297 YP_003104714.1 CDS Amir_7077 NC_013093.1 8224166 8225476 D PFAM: major facilitator superfamily MFS_1; KEGG: bav:BAV0769 transporter; major facilitator superfamily protein 8224166..8225476 Actinosynnema mirum DSM 43827 8331298 YP_003104715.1 CDS Amir_7079 NC_013093.1 8225881 8227389 R KEGG: hypothetical protein; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; polynucleotide adenylyltransferase/metal dependent phosphohydrolase complement(8225881..8227389) Actinosynnema mirum DSM 43827 8331300 YP_003104716.1 CDS Amir_7080 NC_013093.1 8227525 8228049 D PFAM: NUDIX hydrolase; KEGG: mxa:MXAN_4891 hydrolase, NUDIX family; NUDIX hydrolase 8227525..8228049 Actinosynnema mirum DSM 43827 8331301 YP_003104717.1 CDS Amir_7081 NC_013093.1 8228046 8230340 D KEGG: ccs:CCNA_00415 hypothetical protein; hypothetical protein 8228046..8230340 Actinosynnema mirum DSM 43827 8331302 YP_003104718.1 CDS Amir_7082 NC_013093.1 8230406 8231971 D PFAM: virulence factor MVIN family protein; KEGG: glo:Glov_2048 integral membrane protein MviN; virulence factor MVIN family protein 8230406..8231971 Actinosynnema mirum DSM 43827 8331303 YP_003104719.1 CDS Amir_7083 NC_013093.1 8232009 8233517 D KEGG: azo:azo3774 serine/threonine protein kinase; hypothetical protein 8232009..8233517 Actinosynnema mirum DSM 43827 8331304 YP_003104720.1 CDS Amir_7084 NC_013093.1 8233657 8234268 D TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: sus:Acid_7940 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 8233657..8234268 Actinosynnema mirum DSM 43827 8331305 YP_003104721.1 CDS Amir_7085 NC_013093.1 8234265 8235128 D KEGG: mno:Mnod_6604 hypothetical protein; hypothetical protein 8234265..8235128 Actinosynnema mirum DSM 43827 8331306 YP_003104722.1 CDS Amir_7086 NC_013093.1 8235340 8236335 D KEGG: acp:A2cp1_4094 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; thioredoxin reductase 8235340..8236335 Actinosynnema mirum DSM 43827 8331307 YP_003104723.1 CDS Amir_7087 NC_013093.1 8236364 8236690 D TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: gdi:GDI0716 thioredoxin; thioredoxin 8236364..8236690 Actinosynnema mirum DSM 43827 8331308 YP_003104724.1 CDS Amir_7088 NC_013093.1 8236887 8238026 D PFAM: cell wall hydrolase/autolysin; peptidoglycan- binding domain 1 protein; SMART: cell wall hydrolase/autolysin; KEGG: bha:BH3665 N-acetylmuramoyl-L-alanine amidase (major autolysin); cell wall hydrolase/autolysin 8236887..8238026 Actinosynnema mirum DSM 43827 8331309 YP_003104725.1 CDS Amir_7089 NC_013093.1 8238152 8238784 R hypothetical protein complement(8238152..8238784) Actinosynnema mirum DSM 43827 8331310 YP_003104726.1 CDS Amir_7090 NC_013093.1 8238936 8240252 D PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein; GntR family transcriptional regulator 8238936..8240252 Actinosynnema mirum DSM 43827 8331311 YP_003104727.1 CDS Amir_7091 NC_013093.1 8240266 8241210 D PFAM: D-alanine--D-alanine ligase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP- grasp; KEGG: afw:Anae109_3887 D-alanine--D-alanine ligase; D-alanine--D-alanine ligase 8240266..8241210 Actinosynnema mirum DSM 43827 8331312 YP_003104728.1 CDS Amir_7092 NC_013093.1 8241299 8242294 R KEGG: acp:A2cp1_4509 ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; parB-like partition protein complement(8241299..8242294) Actinosynnema mirum DSM 43827 8331313 YP_003104729.1 CDS Amir_7093 NC_013093.1 8242291 8243310 R PFAM: cobyrinic acid ac-diamide synthase; KEGG: bsu:BSU40970 chromosome partitioning protein; transcriptional regulator; cobyrinic acid ac-diamide synthase complement(8242291..8243310) Actinosynnema mirum DSM 43827 8331314 YP_003104730.1 CDS Amir_7094 NC_013093.1 8243312 8243983 R TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: cak:Caul_5025 methyltransferase GidB; methyltransferase GidB complement(8243312..8243983) Actinosynnema mirum DSM 43827 8331315 YP_003104731.1 CDS Amir_7095 NC_013093.1 8244537 8245004 R PFAM: NUDIX hydrolase; KEGG: bcr:BCAH187_A2810 MutT/NUDIX family protein; NUDIX hydrolase complement(8244537..8245004) Actinosynnema mirum DSM 43827 8331316 YP_003104732.1 CDS Amir_7096 NC_013093.1 8245383 8245934 R PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: bha:BH4063 spoIIIJ-associated protein; single-stranded nucleic acid binding R3H domain-containing protein complement(8245383..8245934) Actinosynnema mirum DSM 43827 8331317 YP_003104733.1 CDS Amir_7097 NC_013093.1 8245963 8247039 R PFAM: 60 kDa inner membrane insertion protein; KEGG: mmw:Mmwyl1_4485 60 kDa inner membrane insertion protein; 60 kDa inner membrane insertion protein complement(8245963..8247039) Actinosynnema mirum DSM 43827 8331318 YP_003104734.1 CDS Amir_7098 NC_013093.1 8247043 8247312 R PFAM: protein of unknown function DUF37; KEGG: ade:Adeh_4359 hypothetical protein; hypothetical protein complement(8247043..8247312) Actinosynnema mirum DSM 43827 8331319 YP_003104735.1 CDS Amir_7099 NC_013093.1 8247309 8247554 R PFAM: ribonuclease P protein; KEGG: sal:Sala_0006 ribonuclease P protein component; ribonuclease P protein complement(8247309..8247554) Actinosynnema mirum DSM 43827 8331320 YP_003104736.1 CDS Amir_7100 NC_013093.1 8247667 8247810 R TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; KEGG: aba:Acid345_0220 LSU ribosomal protein L34P; 50S ribosomal protein L34 complement(8247667..8247810) Actinosynnema mirum DSM 43827 8331321 Amir_R0001 tRNA Amir_R0001 NC_013093.1 12199 12275 D tRNA-Ile 12199..12275 Actinosynnema mirum DSM 43827 8324151 Amir_R0002 tRNA Amir_R0002 NC_013093.1 12465 12537 D tRNA-Ala 12465..12537 Actinosynnema mirum DSM 43827 8324153 Amir_R0003 tRNA Amir_R0003 NC_013093.1 31268 31353 D tRNA-Leu 31268..31353 Actinosynnema mirum DSM 43827 8324172 Amir_R0004 tRNA Amir_R0004 NC_013093.1 70827 70899 R tRNA-Gly complement(70827..70899) Actinosynnema mirum DSM 43827 8324206 Amir_R0005 tRNA Amir_R0005 NC_013093.1 156905 156989 D tRNA-Ser 156905..156989 Actinosynnema mirum DSM 43827 8324291 Amir_R0006 tRNA Amir_R0006 NC_013093.1 166068 166159 D tRNA-Ser 166068..166159 Actinosynnema mirum DSM 43827 8324300 Amir_R0007 tRNA Amir_R0007 NC_013093.1 166198 166273 D tRNA-Arg 166198..166273 Actinosynnema mirum DSM 43827 8324301 Amir_R0008 tRNA Amir_R0008 NC_013093.1 186714 186798 D tRNA-Ser 186714..186798 Actinosynnema mirum DSM 43827 8324321 Amir_R0009 tRNA Amir_R0009 NC_013093.1 210110 210194 R tRNA-Ser complement(210110..210194) Actinosynnema mirum DSM 43827 8324348 Amir_R0015 tRNA Amir_R0015 NC_013093.1 258064 258140 R tRNA-Pro complement(258064..258140) Actinosynnema mirum DSM 43827 8324389 Amir_R0016 tRNA Amir_R0016 NC_013093.1 322589 322662 D tRNA-Thr 322589..322662 Actinosynnema mirum DSM 43827 8324452 Amir_R0017 tRNA Amir_R0017 NC_013093.1 406492 406567 D tRNA-Thr 406492..406567 Actinosynnema mirum DSM 43827 8324532 Amir_R0018 tRNA Amir_R0018 NC_013093.1 662462 662534 R tRNA-Arg complement(662462..662534) Actinosynnema mirum DSM 43827 8324758 Amir_R0019 tRNA Amir_R0019 NC_013093.1 694477 694549 D tRNA-Ala 694477..694549 Actinosynnema mirum DSM 43827 8324792 Amir_R0020 tRNA Amir_R0020 NC_013093.1 728000 728073 R tRNA-Gln complement(728000..728073) Actinosynnema mirum DSM 43827 8324820 Amir_R0021 tRNA Amir_R0021 NC_013093.1 767920 767994 D tRNA-Leu 767920..767994 Actinosynnema mirum DSM 43827 8324854 Amir_R0025 tRNA Amir_R0025 NC_013093.1 1047389 1047465 D tRNA-Met 1047389..1047465 Actinosynnema mirum DSM 43827 8325108 Amir_R0026 tRNA Amir_R0026 NC_013093.1 1047700 1047776 D tRNA-Met 1047700..1047776 Actinosynnema mirum DSM 43827 8325109 Amir_R0027 tRNA Amir_R0027 NC_013093.1 1048004 1048080 D tRNA-Met 1048004..1048080 Actinosynnema mirum DSM 43827 8325110 Amir_R0029 tRNA Amir_R0029 NC_013093.1 1064385 1064460 D tRNA-Ala 1064385..1064460 Actinosynnema mirum DSM 43827 8325127 Amir_R0030 tRNA Amir_R0030 NC_013093.1 1139227 1139302 R tRNA-Leu complement(1139227..1139302) Actinosynnema mirum DSM 43827 8325200 Amir_R0031 tRNA Amir_R0031 NC_013093.1 1170947 1171019 R tRNA-Lys complement(1170947..1171019) Actinosynnema mirum DSM 43827 8325226 Amir_R0032 tRNA Amir_R0032 NC_013093.1 1174188 1174263 R tRNA-His complement(1174188..1174263) Actinosynnema mirum DSM 43827 8325229 Amir_R0033 tRNA Amir_R0033 NC_013093.1 1238174 1238246 R tRNA-Arg complement(1238174..1238246) Actinosynnema mirum DSM 43827 8325293 Amir_R0034 tRNA Amir_R0034 NC_013093.1 1281292 1281365 R tRNA-Gly complement(1281292..1281365) Actinosynnema mirum DSM 43827 8325326 Amir_R0035 tRNA Amir_R0035 NC_013093.1 1281427 1281500 D tRNA-Pro 1281427..1281500 Actinosynnema mirum DSM 43827 8325327 Amir_R0036 tRNA Amir_R0036 NC_013093.1 1430483 1430557 R tRNA-Met complement(1430483..1430557) Actinosynnema mirum DSM 43827 8325472 Amir_R0037 tRNA Amir_R0037 NC_013093.1 1431640 1431711 R tRNA-Asn complement(1431640..1431711) Actinosynnema mirum DSM 43827 8325474 Amir_R0038 tRNA Amir_R0038 NC_013093.1 1480319 1480393 D tRNA-Val 1480319..1480393 Actinosynnema mirum DSM 43827 8325516 Amir_R0043 tRNA Amir_R0043 NC_013093.1 1781567 1781640 D tRNA-Pro 1781567..1781640 Actinosynnema mirum DSM 43827 8325803 Amir_R0044 tRNA Amir_R0044 NC_013093.1 2234118 2234189 R tRNA-Val complement(2234118..2234189) Actinosynnema mirum DSM 43827 8326200 Amir_R0045 tRNA Amir_R0045 NC_013093.1 2234191 2234262 R tRNA-Cys complement(2234191..2234262) Actinosynnema mirum DSM 43827 8326201 Amir_R0046 tRNA Amir_R0046 NC_013093.1 2234323 2234395 R tRNA-Gly complement(2234323..2234395) Actinosynnema mirum DSM 43827 8326202 Amir_R0047 tRNA Amir_R0047 NC_013093.1 2237137 2237211 D tRNA-Val 2237137..2237211 Actinosynnema mirum DSM 43827 8326207 Amir_R0048 tRNA Amir_R0048 NC_013093.1 3457184 3457257 D tRNA-Leu 3457184..3457257 Actinosynnema mirum DSM 43827 8327179 Amir_R0049 tRNA Amir_R0049 NC_013093.1 4409046 4409121 D tRNA-Trp 4409046..4409121 Actinosynnema mirum DSM 43827 8327941 Amir_R0050 tRNA Amir_R0050 NC_013093.1 4409157 4409232 D tRNA-His 4409157..4409232 Actinosynnema mirum DSM 43827 8327942 Amir_R0051 tRNA Amir_R0051 NC_013093.1 4538336 4538410 D tRNA-Val 4538336..4538410 Actinosynnema mirum DSM 43827 8328065 Amir_R0052 tRNA Amir_R0052 NC_013093.1 5010745 5010818 R tRNA-Glu complement(5010745..5010818) Actinosynnema mirum DSM 43827 8328445 Amir_R0053 tRNA Amir_R0053 NC_013093.1 5010893 5010966 R tRNA-Gly complement(5010893..5010966) Actinosynnema mirum DSM 43827 8328446 Amir_R0054 tRNA Amir_R0054 NC_013093.1 5011064 5011137 R tRNA-Ala complement(5011064..5011137) Actinosynnema mirum DSM 43827 8328447 Amir_R0055 tRNA Amir_R0055 NC_013093.1 5011179 5011255 R tRNA-Ala complement(5011179..5011255) Actinosynnema mirum DSM 43827 8328448 Amir_R0056 tRNA Amir_R0056 NC_013093.1 5388834 5388919 D tRNA-Leu 5388834..5388919 Actinosynnema mirum DSM 43827 8328742 Amir_R0065 tRNA Amir_R0065 NC_013093.1 6660070 6660146 R tRNA-Leu complement(6660070..6660146) Actinosynnema mirum DSM 43827 8329854 Amir_R0066 tRNA Amir_R0066 NC_013093.1 7052607 7052679 R tRNA-Glu complement(7052607..7052679) Actinosynnema mirum DSM 43827 8330215 Amir_R0067 tRNA Amir_R0067 NC_013093.1 7052741 7052816 R tRNA-Glu complement(7052741..7052816) Actinosynnema mirum DSM 43827 8330216 Amir_R0068 tRNA Amir_R0068 NC_013093.1 7052877 7052948 R tRNA-Gln complement(7052877..7052948) Actinosynnema mirum DSM 43827 8330217 Amir_R0069 tRNA Amir_R0069 NC_013093.1 7221879 7221953 D tRNA-Arg 7221879..7221953 Actinosynnema mirum DSM 43827 8330373 Amir_R0070 tRNA Amir_R0070 NC_013093.1 7617132 7617204 R tRNA-OTHER complement(7617132..7617204) Actinosynnema mirum DSM 43827 8330692 Amir_R0071 tRNA Amir_R0071 NC_013093.1 7777322 7777394 R tRNA-Trp complement(7777322..7777394) Actinosynnema mirum DSM 43827 8330855 Amir_R0072 tRNA Amir_R0072 NC_013093.1 7781631 7781703 R tRNA-Met complement(7781631..7781703) Actinosynnema mirum DSM 43827 8330862 Amir_R0073 tRNA Amir_R0073 NC_013093.1 7781748 7781823 R tRNA-Thr complement(7781748..7781823) Actinosynnema mirum DSM 43827 8330863 Amir_R0074 tRNA Amir_R0074 NC_013093.1 7787474 7787557 R tRNA-Tyr complement(7787474..7787557) Actinosynnema mirum DSM 43827 8330868 Amir_R0075 tRNA Amir_R0075 NC_013093.1 7929685 7929761 R tRNA-Phe complement(7929685..7929761) Actinosynnema mirum DSM 43827 8331011 Amir_R0076 tRNA Amir_R0076 NC_013093.1 7929793 7929869 R tRNA-Asp complement(7929793..7929869) Actinosynnema mirum DSM 43827 8331012 Amir_R0077 tRNA Amir_R0077 NC_013093.1 7929904 7929976 R tRNA-Glu complement(7929904..7929976) Actinosynnema mirum DSM 43827 8331013 Amir_R0078 tRNA Amir_R0078 NC_013093.1 7945376 7945451 D tRNA-Lys 7945376..7945451 Actinosynnema mirum DSM 43827 8331026 Amir_R0079 tRNA Amir_R0079 NC_013093.1 8091012 8091082 D tRNA-Gly 8091012..8091082 Actinosynnema mirum DSM 43827 8331180 Amir_R0011 rRNA Amir_R0011 NC_013093.1 219650 221154 D 16S ribosomal RNA 219650..221154 Actinosynnema mirum DSM 43827 8324357 Amir_R0012 rRNA Amir_R0012 NC_013093.1 221505 224583 D 23S ribosomal RNA 221505..224583 Actinosynnema mirum DSM 43827 8324358 Amir_R0013 rRNA Amir_R0013 NC_013093.1 224708 224824 D 5S ribosomal RNA 224708..224824 Actinosynnema mirum DSM 43827 8324359 Amir_R0023 rRNA Amir_R0023 NC_013093.1 1008774 1010278 D 16S ribosomal RNA 1008774..1010278 Actinosynnema mirum DSM 43827 8325075 Amir_R0024 rRNA Amir_R0024 NC_013093.1 1010624 1013650 D 23S ribosomal RNA 1010624..1013650 Actinosynnema mirum DSM 43827 8325076 Amir_R0039 rRNA Amir_R0039 NC_013093.1 1686555 1688059 D 16S ribosomal RNA 1686555..1688059 Actinosynnema mirum DSM 43827 8325708 Amir_R0040 rRNA Amir_R0040 NC_013093.1 1688405 1691482 D 23S ribosomal RNA 1688405..1691482 Actinosynnema mirum DSM 43827 8325709 Amir_R0041 rRNA Amir_R0041 NC_013093.1 1691611 1691727 D 5S ribosomal RNA 1691611..1691727 Actinosynnema mirum DSM 43827 8325710 Amir_R0057 rRNA Amir_R0057 NC_013093.1 6126031 6126146 R 5S ribosomal RNA complement(6126031..6126146) Actinosynnema mirum DSM 43827 8329341 Amir_R0059 rRNA Amir_R0059 NC_013093.1 6126273 6129350 R 23S ribosomal RNA complement(6126273..6129350) Actinosynnema mirum DSM 43827 8329343 Amir_R0060 rRNA Amir_R0060 NC_013093.1 6129696 6131200 R 16S ribosomal RNA complement(6129696..6131200) Actinosynnema mirum DSM 43827 8329344 Amir_R0061 rRNA Amir_R0061 NC_013093.1 6464679 6464794 R 5S ribosomal RNA complement(6464679..6464794) Actinosynnema mirum DSM 43827 8329647 Amir_R0063 rRNA Amir_R0063 NC_013093.1 6464925 6468002 R 23S ribosomal RNA complement(6464925..6468002) Actinosynnema mirum DSM 43827 8329649 Amir_R0064 rRNA Amir_R0064 NC_013093.1 6468349 6469854 R 16S ribosomal RNA complement(6468349..6469854) Actinosynnema mirum DSM 43827 8329650