-- dump date 20140618_193150 -- class Genbank::CDS -- table cds_note -- id note YP_004277318.1 Protein of unknown function DUF299; Uncharacterized protein conserved in bacteria YP_004277319.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Nucleotide-binding protein implicated in inhibition of septum formation YP_004277320.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_004277321.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_004277322.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases YP_004277323.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_004277324.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; Protein affecting phage T7 exclusion by the F plasmid YP_004277325.1 Mitochondrial import inner membrane translocase, subunit Tim44; Uncharacterized protein conserved in bacteria YP_004277326.1 MltA specific insert domain YP_004277327.1 Smr protein/MutS2 C-terminal; Uncharacterized protein conserved in bacteria YP_004277328.1 Lambda repressor-like, DNA-binding, Helix-turn-helix; Predicted transcriptional regulators YP_004277329.1 negatively supercoils closed circular double-stranded DNA; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit YP_004277330.1 Nitroreductase YP_004277331.1 Fumarylacetoacetate (FAA) hydrolase family, HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene- 1,7-dioic acid hydratase (catechol pathway) YP_004277332.1 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular; Poly-beta-hydroxyalkanoate depolymerase YP_004277333.1 Protein of unknown function DUF45; Predicted metal-dependent hydrolase YP_004277334.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; Phosphoribosylanthranilate isomerase YP_004277335.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; Tryptophan synthase beta chain YP_004277336.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; Tryptophan synthase alpha chain YP_004277337.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; Acetyl-CoA carboxylase beta subunit YP_004277338.1 Folylpolyglutamate synthetase, folC: FolC bifunctional protein YP_004277339.1 Thioredoxin domain; Thiol-disulfide isomerase and thioredoxins YP_004277340.1 DNA helicase (double-strand break repair), AddA type, UvrD/REP helicase; ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) YP_004277341.1 addB_alphas: double-strand break repair protein AddB; Inactivated superfamily I helicase YP_004277342.1 Nucleotidyl transferase; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF- 2Bgamma/eIF-2Bepsilon) YP_004277343.1 Bifunctional ATPase/phosphotransferase, cell wall biosynthesis, Uncharacterised P-loop hydrolase UPF0079; Predicted phosphotransferase related to Ser/Thr protein kinases YP_004277344.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Osmosensitive K+ channel histidine kinase YP_004277346.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosylhomocysteine hydrolase YP_004277347.1 Phosphotransferase system, phosphocarrier HPr protein, PTS_HPr_family: phosphocarrier, HPr family; Phosphotransferase system, HPr-related proteins YP_004277348.1 Phosphotransferase system, fructose subfamily IIA component, PTS system fructose IIA component; Phosphotransferase system, mannose/fructose- specific component IIA YP_004277349.1 HPr kinase/phosphorylase; HPrK/P; Serine kinase of the HPr protein, regulates carbohydrate metabolism YP_004277350.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004277351.1 CheY-like, Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004277352.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; Phosphoenolpyruvate carboxykinase (ATP) YP_004277353.1 Class I peptide chain release factor, Peptidyl-tRNA hydrolase domain; Protein chain release factor B YP_004277354.1 Transport-associated; Uncharacterized protein containing LysM domain YP_004277355.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Panthothenate kinase YP_004277356.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Phosphoribosyl-ATP pyrophosphohydrolase YP_004277357.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; Imidazoleglycerol-phosphate synthase YP_004277358.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase YP_004277359.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; Glutamine amidotransferase YP_004277360.1 Protein of unknown function (DUF2506) YP_004277361.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_004277362.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease HslVU (ClpYQ), peptidase subunit YP_004277363.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease HslVU (ClpYQ), ATPase subunit YP_004277364.1 Protein of unknown function DUF1402 YP_004277365.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; Malate synthase YP_004277366.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004277367.1 Protein of unknown function DUF1052; Uncharacterized protein conserved in bacteria YP_004277368.1 CheY-like, Response regulator receiver domain; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain YP_004277369.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004277370.1 RNA helicase, ATP-dependent DEAH box, HrpB type, ATP-dependent helicase C-terminal; HrpA-like helicases YP_004277372.1 DNA helicase, ATP-dependent, RecQ type; Superfamily II DNA helicase YP_004277373.1 ROK family transcriptional regulator; Transcriptional regulator/sugar kinase YP_004277374.1 ABC transporter substrate-binding protein (sugar); ABC-type sugar transport system, periplasmic component YP_004277375.1 Branched-chain amino acid transport system / permease component; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004277376.1 ABC transporter nucleotide-binding protein/ATPase (sugar); ABC-type sugar transport system, ATPase component YP_004277377.1 fructose transport system kinase YP_004277378.1 GlrX_NrdH: Glutaredoxin-like protein NrdH YP_004277379.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_004277380.1 Catalyzes the rate-limiting step in dNTP synthesis; Ribonucleotide reductase, subunit alpha YP_004277381.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; Ribonucleotide reductase, beta subunit YP_004277382.1 Uncharacterised conserved protein UCP033909, Alpha/beta hydrolase of unknown function (DUF900); Uncharacterized protein conserved in bacteria YP_004277383.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; Recombinational DNA repair ATPase (RecF pathway) YP_004277384.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 YP_004277385.1 Acetyltransferases YP_004277386.1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Lactate dehydrogenase and related dehydrogenases YP_004277387.1 Bacterial SH3-like region; Uncharacterized protein conserved in bacteria YP_004277388.1 pfkB family carbohydrate kinase; Sugar kinases, ribokinase family YP_004277389.1 Auxin efflux carrier, Membrane transport protein; Predicted permeases YP_004277390.1 16S RNA G1207 methylase RsmC YP_004277391.1 polynucleotide phosphorylase/polyadenylase; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) YP_004277392.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; Ribosomal protein S15P/S13E YP_004277393.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; Pseudouridine synthase YP_004277394.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_004277395.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Translation initiation factor 2 (IF-2; GTPase) YP_004277396.1 Protein of unknown function DUF448; Predicted nucleic-acid-binding protein implicated in transcription termination YP_004277397.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; Transcription elongation factor YP_004277398.1 Protein of unknown function DUF150; Uncharacterized protein conserved in bacteria YP_004277399.1 Protein of unknown function DUF894, DitE; Permeases of the major facilitator superfamily YP_004277400.1 Membrane-bound lytic murein transglycosylase B YP_004277401.1 involved in a recombinational process of DNA repair, independent of the recBC complex; Recombinational DNA repair protein (RecF pathway) YP_004277402.1 Molybdenum cofactor sulphurase, C-terminal-like; Uncharacterized protein conserved in bacteria YP_004277403.1 Conserved hypothetical protein CHP00103, Uncharacterised BCR, YbaB family COG0718; Uncharacterized protein conserved in bacteria YP_004277404.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III, gamma/tau subunits YP_004277405.1 Histidine triad-like motif; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases YP_004277406.1 NADH pyrophosphatase-like rudimentary NUDIX domain; NTP pyrophosphohydrolases containing a Zn- finger, probably nucleic-acid-binding YP_004277407.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_004277408.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; CMP-2-keto-3-deoxyoctulosonic acid synthetase YP_004277409.1 Cytochrome c, class IA/ IB; Cytochrome c2 YP_004277410.1 Bacterial sugar transferase; Sugar transferases involved in lipopolysaccharide synthesis YP_004277411.1 Membrane carboxypeptidase (penicillin-binding protein) YP_004277412.1 YbaK/prolyl-tRNA synthetase associated region; Uncharacterized conserved protein YP_004277414.1 'Cold-shock' DNA-binding domain; Cold shock proteins YP_004277415.1 Peptidase family M20/M25/M40; Acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases YP_004277416.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004277417.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I - 3'-5' exonuclease and polymerase domains YP_004277418.1 Domain of unknown function (DUF1868); Uncharacterized protein conserved in bacteria YP_004277419.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; Ribosomal protein L32 YP_004277420.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase regulating C4-dicarboxylate transport system YP_004277421.1 RNA polymerase sigma factor 54, interaction, Sigma-54 interaction domain; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains YP_004277422.1 Uncharacterized protein conserved in bacteria YP_004277423.1 Protein of unknown function DUF1468 YP_004277424.1 Protein of unknown function DUF112, transmembrane; Uncharacterized protein conserved in bacteria YP_004277425.1 SlyX YP_004277426.1 Protein of unknown function DUF924, bacterial; Uncharacterized protein conserved in bacteria YP_004277427.1 DnaJ C terminal region; DnaJ-class molecular chaperone with C-terminal Zn finger domain YP_004277428.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Molecular chaperone YP_004277431.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; Peptide methionine sulfoxide reductase YP_004277432.1 Basic membrane lipoprotein; Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein YP_004277433.1 ABC transporter nucleotide-binding protein/ATPase (sugar/ribonucleotide); ABC-type uncharacterized transport systems, ATPase components YP_004277434.1 ABC transporter transmembrane protein (sugar/ribonucleotide); ABC-type uncharacterized transport system, permease component YP_004277435.1 ABC transporter transmembrane protein (sugar/ribonucleotide); Uncharacterized ABC-type transport system, permease component YP_004277436.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_004277437.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_004277438.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_004277439.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_004277440.1 Conserved hypothetical protein CHP02281; Predicted aspartyl protease YP_004277441.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_004277442.1 catalyzes the formation of inosine from adenosine YP_004277443.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_004277444.1 Surfeit locus 1; Uncharacterized conserved protein YP_004277445.1 Heme/copper-type cytochrome/quinol oxidase, subunit 4 YP_004277446.1 CyoC: cytochrome o ubiquinol oxidase, subunit III; Heme/copper-type cytochrome/quinol oxidase, subunit 3 YP_004277447.1 Cytochrome o ubiquinol oxidase, subunit I; Heme/copper-type cytochrome/quinol oxidases, subunit 1 YP_004277448.1 CyoA: ubiquinol oxidase, subunit II; Heme/copper-type cytochrome/quinol oxidases, subunit 2 YP_004277449.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004277451.1 Conserved region in glutamate synthase; Glutamate synthase domain 2 YP_004277452.1 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component; Sulfite reductase, subunit alpha (flavoprotein) YP_004277453.1 Flp pilus assembly protein TadG YP_004277454.1 Flp pilus assembly protein TadG YP_004277455.1 Catalyzes a key regulatory step in fatty acid biosynthesis; Enoyl-ACP reductase (NADH) YP_004277456.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase YP_004277457.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases YP_004277458.1 Ferric uptake regulator family; Fe2+/Zn2+ uptake regulation proteins YP_004277459.1 Protein of unknown function UPF0126; Predicted membrane protein YP_004277461.1 Protein of unknown function DUF1275; Predicted membrane protein YP_004277462.1 ABC transporter substrate-binding protein; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004277463.1 ABC transporter transmembrane protein; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004277464.1 ABC transporter nucleotide-binding protein/ATPase; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004277465.1 Histidine utilization repressor; Transcriptional regulators YP_004277466.1 TonB-system energizer ExbB type-1; Biopolymer transport proteins YP_004277467.1 Biopolymer transport protein ExbD/TolR YP_004277468.1 TonB, C-terminal; Periplasmic protein TonB, links inner and outer membranes YP_004277469.1 Malate/L-lactate dehydrogenases YP_004277470.1 Winged helix repressor DNA-binding YP_004277471.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004277472.1 Guanylate kinase/L-type calcium channel region; Uncharacterized component of phosphonate metabolism YP_004277473.1 phosphono_phnM: phosphonate metabolism protein PhnM; Metal-dependent hydrolase involved in phosphonate metabolism YP_004277474.1 Protein of unknown function DUF1045 YP_004277475.1 ABC transporter transmembrane protein (phosphonate); ABC-type phosphate/phosphonate transport system, permease component YP_004277476.1 ABC transporter transmembrane protein (phosphonate); ABC-type phosphate/phosphonate transport system, permease component YP_004277477.1 ABC transporter substrate-binding protein (phosphonate); ABC-type phosphate/phosphonate transport system, periplasmic component YP_004277478.1 ABC transporter nucleotide-binding protein/ATPase (phosphonate); ABC-type phosphate/phosphonate transport system, ATPase component YP_004277479.1 Trimeric LpxA-like; Acetyltransferase (isoleucine patch superfamily) YP_004277480.1 ABC transporter nucleotide-binding protein/ATPase (phosphonate); ABC-type phosphonate transport system, ATPase component YP_004277481.1 ABC-type phosphonate transport system, ATPase component YP_004277482.1 Phosphonate metabolism protein PhnJ; Uncharacterized enzyme of phosphonate metabolism YP_004277484.1 Bacterial phosphonate metabolism protein; Uncharacterized enzyme of phosphonate metabolism YP_004277485.1 Bacterial phosphonate metabolism protein; Uncharacterized enzyme of phosphonate metabolism YP_004277486.1 Phosphonate metabolism protein PhnG; Uncharacterized enzyme of phosphonate metabolism YP_004277487.1 C_P_lyase_phnF: phosphonates metabolism transcriptional regulator PhnF; Transcriptional regulators YP_004277488.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_004277489.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_004277490.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_004277491.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; forms a dimer in periplasm; Murein endopeptidase YP_004277492.1 ABC transporter substrate-binding protein (peptide); ABC-type oligopeptide transport system, periplasmic component YP_004277493.1 ABC transporter transmembrane protein (peptide); ABC-type uncharacterized transport system, permease component YP_004277494.1 ABC transporter transmembrane protein (peptide); ABC-type uncharacterized transport system, permease component YP_004277495.1 ABC transporter nucleotide-binding protein/ATPase (peptide); ABC-type uncharacterized transport system, duplicated ATPase component YP_004277496.1 glycine/D-amino acid oxidases (deaminating) YP_004277498.1 FAD dependent oxidoreductase; glycine/D-amino acid oxidases (deaminating) YP_004277499.1 Carbohydrate kinase, thermoresistant glucokinase; Gluconate kinase YP_004277500.1 ABC transporter transmembrane protein (proline/glycine/betaine); ABC-type proline/glycine betaine transport systems, permease component YP_004277501.1 ABC transporter nucleotide-binding protein/ATPase (proline/glycine/betaine); ABC-type oligopeptide transport system, ATPase component YP_004277502.1 ABC transporter transmembrane protein (proline/glycine/betaine); ABC-type proline/glycine betaine transport systems, permease component YP_004277503.1 ABC transporter substrate-binding protein (proline/glycine/betaine); Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) YP_004277505.1 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons; Predicted transcriptional regulator YP_004277506.1 ABC transporter substrate-binding protein (iron); ABC-type Fe3+ transport system, periplasmic component YP_004277507.1 NAD-dependent aldehyde dehydrogenases YP_004277508.1 Dimeric alpha-beta barrel; Uncharacterized conserved protein YP_004277509.1 LysR substrate binding domain; Transcriptional regulator YP_004277510.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004277511.1 Protein of unknown function DUF475; Uncharacterized protein conserved in bacteria YP_004277512.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004277513.1 NlpC/P60 family; Cell wall-associated hydrolases (invasion- associated proteins) YP_004277515.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; Nicotinic acid phosphoribosyltransferase YP_004277516.1 Leucyl aminopeptidase YP_004277517.1 Uncharacterised conserved protein UCP035836; Flp pilus assembly protein TadD, contains TPR repeats YP_004277518.1 Flp pilus assembly protein TadC YP_004277519.1 Flp pilus assembly protein TadB YP_004277520.1 Flp pilus assembly protein, ATPase CpaF YP_004277521.1 CheY-like; Flp pilus assembly protein, ATPase CpaE YP_004277522.1 Pilus biogenesis CpaD; Type IV pili component YP_004277523.1 Flp pilus assembly protein, secretin CpaC YP_004277524.1 SAF domain; Flp pilus assembly protein CpaB YP_004277525.1 components of type IV pilus, prepilin peptidase; Flp pilus assembly protein, protease CpaA YP_004277526.1 Flp/Fap pilin component YP_004277527.1 Flp pilus assembly protein, secretin CpaC YP_004277528.1 Selenoprotein W-related family; Uncharacterized protein conserved in bacteria YP_004277529.1 DoxX; Predicted membrane protein YP_004277530.1 Glutamine amidotransferase class-I; GMP synthase - Glutamine amidotransferase domain YP_004277531.1 Protein of unknown function DUF1508 YP_004277532.1 glycoside hydrolase, catalytic core, glycosyl hydrolases family 25; Lyzozyme M1 (1,4-beta-N-acetylmuramidase) YP_004277533.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004277534.1 Pyridoxal phosphate-dependent transferase, major region; Transcriptional regulators containing a DNA- binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs YP_004277536.1 Transcriptional regulator, Rrf2; Predicted transcriptional regulator YP_004277537.1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Thioredoxin reductase YP_004277538.1 AraC protein, arabinose-binding/dimerisation; AraC-type DNA-binding domain-containing proteins YP_004277539.1 Protein of unknown function (DUF2000); Uncharacterized protein conserved in bacteria YP_004277540.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; Membrane GTPase LepA YP_004277541.1 Predicted amidohydrolase YP_004277543.1 Conserved hypothetical protein CHP02096; Ketosteroid isomerase-related protein YP_004277544.1 Cupin, RmlC-type; Predicted transcriptional regulators YP_004277545.1 GCN5-related N-acetyltransferase; Acetyltransferases YP_004277548.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004277549.1 Bacterial extracellular solute-binding protein, family 7; TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component YP_004277550.1 Globin-like; Truncated hemoglobins YP_004277551.1 Ferritin/ribonucleotide reductase-like, Rubrerythrin; Uncharacterized conserved protein YP_004277552.1 Predicted transglutaminase-like cysteine peptidase, BTLCP, Bacterial protein of unknown function (DUF920); Predicted periplasmic protein YP_004277553.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004277554.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; Translation initiation factor 3 (IF-3) YP_004277555.1 Ribosomal protein L35 YP_004277556.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; Ribosomal protein L20 YP_004277557.1 Protein kinase-like YP_004277558.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Phenylalanyl-tRNA synthetase subunit alpha YP_004277559.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; Phenylalanyl-tRNA synthetase beta subunit YP_004277560.1 Aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004277561.1 LysR substrate binding domain; Transcriptional regulator YP_004277562.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases YP_004277563.1 oxidoreductase, aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004277564.1 ThiJ/PfpI; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_004277565.1 Amidases related to nicotinamidase YP_004277566.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004277569.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; Exonuclease VII, large subunit YP_004277570.1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004277571.1 GntR, C-terminal, FCD domain; Transcriptional regulators YP_004277572.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004277573.1 Protein of unknown function DUF6, transmembrane; Threonine/homoserine efflux transporter YP_004277574.1 Leucyl aminopeptidase (aminopeptidase T) YP_004277575.1 YbaK_EbsC: ybaK/ebsC protein; Uncharacterized conserved protein YP_004277576.1 arsC_related: conserved hypothetical protein; Arsenate reductase and related proteins, glutaredoxin family YP_004277578.1 RNA ligase/cyclic nucleotide phosphodiesterase; 2'-5' RNA ligase YP_004277579.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase, PP-ATPase domain/subunit YP_004277580.1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; Nucleoside phosphorylase YP_004277581.1 Phenylacetic acid degradation-related protein, unchar_dom_1: uncharacterized domain 1; Uncharacterized protein, possibly involved in aromatic compounds catabolism YP_004277582.1 TspO/MBR family; Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) YP_004277583.1 Protein of unknown function DUF1513; Uncharacterized protein conserved in bacteria YP_004277584.1 Imelysin; Predicted periplasmic lipoprotein YP_004277585.1 Protein of unknown function DUF1111; Predicted thiol oxidoreductase YP_004277586.1 Uncharacterized iron-regulated protein YP_004277587.1 tRNA and rRNA cytosine-C5-methylases YP_004277588.1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Lipoproteins YP_004277589.1 NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerases YP_004277590.1 Domain of unknown function (DUF1730); Uncharacterized Fe-S protein YP_004277591.1 Glutathione S-transferase, C-terminal-like YP_004277592.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; Uncharacterized bacitracin resistance protein YP_004277594.1 NAD-dependent epimerase/dehydratase; Predicted nucleoside-diphosphate-sugar epimerases YP_004277595.1 Protein of unknown function DUF1330; Uncharacterized conserved protein YP_004277596.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; Orotidine-5'-phosphate decarboxylase YP_004277597.1 Phosphoglycerate mutase family; Broad specificity phosphatase PhoE and related phosphatases YP_004277598.1 NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins; Phospholipid N-methyltransferase YP_004277599.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase sliding clamp subunit (PCNA homolog) YP_004277600.1 Tetrapyrrole (Corrin/Porphyrin) methylases; Predicted methyltransferases YP_004277601.1 Protein of unknown function UPF0102; Predicted endonuclease distantly related to archaeal Holliday junction resolvase YP_004277602.1 Trimeric LpxA-like; Acetyltransferase (isoleucine patch superfamily) YP_004277603.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004277604.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004277605.1 ABC-type sugar transport system, permease component YP_004277606.1 ABC-type sugar transport systems, ATPase components YP_004277607.1 Protein of unknown function (DUF861); Predicted enzyme of the cupin superfamily YP_004277608.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) YP_004277609.1 Mg chelatase-related protein; Predicted ATPase with chaperone activity YP_004277611.1 threonine efflux protein YP_004277612.1 catalyzes the formation of dUMP from dUTP; dUTPase YP_004277613.1 Elongation factor Tu GTP binding domain; Peptide chain release factor RF-3 YP_004277614.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; Phosphopantothenoylcysteinesynthetase/decarboxylase YP_004277615.1 Protein of unknown function DUF419; Uncharacterized protein conserved in bacteria YP_004277617.1 2-polyprenylphenol 6-hydroxylase; Predicted unusual protein kinase YP_004277618.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; methylase involved in ubiquinone/menaquinone biosynthesis YP_004277619.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_004277620.1 Enoyl-CoA hydratase/isomerase family; Enoyl-CoA hydratase/carnithine racemase YP_004277621.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; Ribosomal protein S20 YP_004277622.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; ATPase involved in DNA replication initiation YP_004277623.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases YP_004277624.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; Xanthosine triphosphate pyrophosphatase YP_004277625.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; RNase PH YP_004277626.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; Transcriptional regulator of heat shock gene YP_004277627.1 GrpE nucleotide exchange factor; Molecular chaperone GrpE (heat shock protein) YP_004277628.1 Phosphotransferase system mannitol/fructose- specific IIA domain (Ntr-type) YP_004277629.1 Sigma 54 modulation protein / S30EA ribosomal protein; Ribosome-associated protein Y (PSrp-1) YP_004277631.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog YP_004277632.1 ABC transporter nucleotide-binding protein/ATPase; ABC-type (unclassified) transport system, ATPase component YP_004277633.1 OstA-like protein; Uncharacterized protein conserved in bacteria YP_004277634.1 Protein of unknown function DUF1239; Uncharacterized protein conserved in bacteria YP_004277635.1 proteinase IV; Periplasmic serine proteases (ClpP class) YP_004277636.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; Bacterial nucleoid DNA-binding protein YP_004277638.1 Predicted SAM-dependent methyltransferases YP_004277639.1 rRNA methylases YP_004277641.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004277642.1 hemolysin YP_004277643.1 This protein performs the mismatch recognition step during the DNA repair process; Mismatch repair ATPase (MutS family) YP_004277644.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; UTP:GlnB (protein PII) uridylyltransferase YP_004277645.1 Virulence factor MVIN-like; Uncharacterized membrane protein, virulence factor YP_004277646.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004277647.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_004277648.1 Universal stress protein family; Universal stress protein UspA and related nucleotide-binding proteins YP_004277649.1 NIF system FeS cluster assembly, NifU-like scaffold; Thioredoxin-like proteins and domains YP_004277650.1 O-sialoglycoprotein endopeptidase; Inactive homolog of metal-dependent proteases, molecular chaperone YP_004277651.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases YP_004277652.1 Ferric uptake regulator family; Fe2+/Zn2+ uptake regulation proteins YP_004277654.1 tRNA-i(6)A37 modification enzyme MiaB, Uncharacterized protein family UPF0004, TIGR00089: RNA modification enzyme, MiaB family; 2-methylthioadenine synthetase YP_004277655.1 PhoH-like protein; Phosphate starvation-inducible protein PhoH, ATPase YP_004277656.1 Protein of unknown function UPF0054; Predicted metal-dependent hydrolase YP_004277657.1 Cystathionine beta-synthase, core; Hemolysins and related proteins containing CBS domains YP_004277658.1 Transfers the fatty acyl group on membrane lipoproteins YP_004277659.1 Lambda repressor-like, DNA-binding, Helix-turn-helix; Predicted transcriptional regulators YP_004277660.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_004277661.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; Predicted S-adenosylmethionine-dependent methyltransferase YP_004277662.1 Sugar kinases, ribokinase family YP_004277663.1 RmuC family; Uncharacterized protein conserved in bacteria YP_004277664.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); N-formylmethionyl-tRNA deformylase YP_004277665.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_004277666.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; Pseudouridylate synthase YP_004277668.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is; Acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases YP_004277669.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; Tetrahydrodipicolinate N-succinyltransferase YP_004277670.1 Conserved hypothetical protein CHP00730, Possible lysine decarboxylase; Predicted Rossmann fold nucleotide-binding protein YP_004277671.1 Bacterial chemotaxis sensory transducer, methyl-accepting chemotaxis protein (MCP) signaling domain YP_004277672.1 Inosine-uridine nucleoside N-ribohydrolase YP_004277673.1 Hsp20/alpha crystallin family; Molecular chaperone (small heat shock protein) YP_004277674.1 Protein of unknown function DUF1150; Uncharacterized small protein YP_004277675.1 EF-Hand type YP_004277676.1 haloacid dehalogenase-like hydrolase, Pyr-5-nucltdase: pyrimidine 5'-nucleotidase; Predicted hydrolase (HAD superfamily) YP_004277677.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004277678.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_004277679.1 Uncharacterized protein conserved in bacteria YP_004277680.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; Predicted GTPase YP_004277681.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; Preprotein translocase subunit YidC YP_004277682.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; RNase P protein component YP_004277685.1 Bacterial chemotaxis sensory transducer, methyl-accepting chemotaxis protein (MCP) signaling domain YP_004277686.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004277687.1 methyltransferase type 11; SAM-dependent methyltransferases YP_004277688.1 ABC transporter nucleotide-binding protein/ATPase; ABC-type sugar transport systems, ATPase components YP_004277689.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004277690.1 ABC transporter transmembrane protein; ABC-type sugar transport system, permease component YP_004277691.1 ABC transporter substrate-binding protein (sugar); ABC-type sugar transport system, periplasmic component YP_004277692.1 Metallophosphoesterase; Predicted phosphohydrolases YP_004277693.1 Acetyl-CoA hydrolase/transferase N-terminal domain, coenzyme A transferase YP_004277694.1 Alpha/beta hydrolase of unknown function (DUF900); Uncharacterized protein conserved in bacteria YP_004277695.1 Proline racemase YP_004277696.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; Dihydroorotase YP_004277697.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_004277698.1 Carbohydrate/purine kinase; Sugar kinases, ribokinase family YP_004277699.1 Acetyl esterase (deacetylase) YP_004277700.1 Uncharacterized protein conserved in bacteria YP_004277701.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_004277702.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_004277703.1 activates fatty acids by binding to coenzyme A; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_004277704.1 ABC transporter nucleotide-binding protein/ATPase; ABC-type spermidine/putrescine transport systems, ATPase components YP_004277705.1 Bacterial extracellular solute-binding protein, family 1; ABC-type Fe3+ transport system, periplasmic component YP_004277706.1 ABC transporter transmembrane protein (iron); ABC-type Fe3+ transport system, permease component YP_004277707.1 TonB-dependent siderophore receptor; Outer membrane receptor proteins, mostly Fe transport YP_004277708.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004277709.1 PRC-barrel domain; Uncharacterized protein conserved in bacteria YP_004277710.1 Protein of unknown function DUF982 YP_004277712.1 Protein of unknown function UPF0057 YP_004277713.1 Aldolase-type TIM barrel; Dioxygenases related to 2-nitropropane dioxygenase YP_004277714.1 Helix-turn-helix, Fis-type YP_004277715.1 Polyphosphate kinase 2; Uncharacterized conserved protein YP_004277716.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004277717.1 ptsS_2: phosphate binding protein; ABC-type phosphate transport system, periplasmic component YP_004277718.1 phosphate ABC transporter, permease PstC; ABC-type phosphate transport system, permease component YP_004277719.1 phosphate ABC transporter, permease PstA; ABC-type phosphate transport system, permease component YP_004277720.1 phosphate ABC transporter ATP-binding protein; ABC-type phosphate transport system, ATPase component YP_004277721.1 PhoU family, phosphate transport system regulatory protein PhoU; Phosphate uptake regulator YP_004277722.1 Phosphate regulon transcriptional regulatory protein phoB, Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004277723.1 GcrA cell cycle regulator; Uncharacterized protein conserved in bacteria YP_004277725.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Ornithine/acetylornithine aminotransferase YP_004277726.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_004277727.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Disulfide bond chaperones of the HSP33 family YP_004277728.1 protein associated with Co2+ and Mg2+ efflux; Uncharacterized protein affecting Mg2+/Co2+ transport YP_004277729.1 catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis; Cystathionine beta-lyases/cystathionine gamma- synthases YP_004277730.1 Catalyzes the deamination of dCTP to form dUTP; Deoxycytidine deaminase YP_004277731.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) YP_004277733.1 glycosyl transferase, family 2; glycosyltransferases, probably involved in cell wall biogenesis YP_004277734.1 ABC transporter substrate-binding protein (amino acid); ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004277735.1 Membrane protein involved in the export of O- antigen and teichoic acid YP_004277736.1 O-antigen polymerase; Lipid A core - O-antigen ligase and related enzymes YP_004277737.1 glycoside hydrolase/deacetylase, beta/alpha-barrel, Polysaccharide deacetylase; Predicted xylanase/chitin deacetylase YP_004277738.1 Peptidase S24, S26A, S26B and S26C; Predicted transcriptional regulator YP_004277739.1 CheY-like, Response regulator receiver domain; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_004277740.1 Protein of unknown function DUF952; Uncharacterized protein conserved in bacteria YP_004277741.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_004277742.1 SCP-like extracellular protein; Uncharacterized protein with SCP/PR1 domains YP_004277744.1 methyltransferase type 12; Predicted methyltransferase (contains TPR repeat) YP_004277745.1 Protein of unknown function DUF161, Uncharacterized BCR, YitT family COG1284; Uncharacterized conserved protein YP_004277746.1 Protein of unknown function DUF161, Uncharacterized BCR, YitT family COG1284; Uncharacterized conserved protein YP_004277747.1 Carboxymuconolactone decarboxylase family, ahpD_dom: alkylhydroperoxidase AhpD family core domain; Uncharacterized conserved protein YP_004277748.1 Transcriptional regulator, Rrf2; Predicted transcriptional regulator YP_004277749.1 DEAD-like helicase, N-terminal, DEAD/H associated; Lhr-like helicases YP_004277750.1 Metallophosphoesterase; Predicted ICC-like phosphoesterases YP_004277751.1 Universal stress protein family; Universal stress protein UspA and related nucleotide-binding proteins YP_004277752.1 Conserved hypothetical protein CHP02186, transmembrane protein (Alph_Pro_TM) YP_004277753.1 Protein of unknown function DUF81; Predicted permeases YP_004277754.1 Tetratricopeptide-like helical, peptidoglycan binding domain; FOG: TPR repeat YP_004277756.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004277757.1 Thiolase, C-terminal domain, AcCoA-C-Actrans: acetyl-CoA acetyltransferases; Acetyl-CoA acetyltransferase YP_004277758.1 Crotonase, core, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase YP_004277760.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Multisubunit Na+/H+ antiporter, MnhG subunit YP_004277761.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; Multisubunit Na+/H+ antiporter, MnhF subunit YP_004277762.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; Multisubunit Na+/H+ antiporter, MnhE subunit YP_004277763.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit YP_004277764.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Multisubunit Na+/H+ antiporter, MnhC subunit YP_004277765.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit YP_004277767.1 Bacterial chemotaxis sensory transducer, methyl-accepting chemotaxis protein (MCP) signaling domain YP_004277768.1 Sulphate transporter/antisigma-factor antagonist STAS; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) YP_004277769.1 CheY-like, Response regulator receiver domain; FOG: CheY-like receiver YP_004277770.1 Signal transducing histidine kinase, homodimeric domain; Chemotaxis protein histidine kinase and related kinases YP_004277771.1 CheR methyltransferase, SAM binding domain; methylase of chemotaxis methyl-accepting proteins YP_004277772.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; Chemotaxis response regulator containing a CheY- like receiver domain and a methylesterase domain YP_004277773.1 CheY-like, Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004277774.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors; Chemotaxis protein; stimulates methylation of MCP proteins YP_004277776.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; Flagellar biosynthesis/type III secretory pathway lipoprotein YP_004277777.1 Winged helix repressor DNA-binding, Bacterial regulatory proteins, luxR family; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_004277778.1 Winged helix repressor DNA-binding; DNA-binding HTH domain-containing proteins YP_004277779.1 Bacterial chemotaxis sensory transducer, methyl-accepting chemotaxis protein (MCP) signaling domain YP_004277781.1 Na+/solute symporter, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, phoR_proteo: phosphate regulon sensor kinase PhoR; Na+/proline symporter YP_004277782.1 Large-conductance mechanosensitive channel YP_004277783.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Aspartate/tyrosine/aromatic aminotransferase YP_004277784.1 UDP-glucose 4-epimerase YP_004277786.1 Zinc finger, NHR/GATA-type; Uncharacterized protein conserved in bacteria YP_004277787.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Nucleotide-binding protein implicated in inhibition of septum formation YP_004277788.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; Translation initiation factor 1 (IF-1) YP_004277789.1 Protein-tyrosine phosphatase, low molecular weight, Low molecular weight phosphotyrosine protein phosphatase; Protein-tyrosine-phosphatase YP_004277790.1 Uncharacterised protein family (UPF0262); Uncharacterized protein conserved in bacteria YP_004277791.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_004277793.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine enolpyruvyl transferase YP_004277795.1 Bacterial flagellin N-terminus; Flagellin and related hook-associated proteins YP_004277796.1 Bacterial flagellin N-terminus, flagella associated protein; Flagellin and related hook-associated proteins YP_004277797.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; Flagellar biosynthesis pathway, component FliP YP_004277798.1 Flagellar basal body-associated protein FliL; Flagellar basal body-associated protein YP_004277799.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_004277800.1 exported flagella related protein; Uncharacterized conserved protein YP_004277801.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; Flagellar basal-body P-ring protein YP_004277802.1 required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella; Flagellar basal body P-ring biosynthesis protein YP_004277803.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; Flagellar basal body rod protein YP_004277804.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; Flagellar hook-basal body protein YP_004277805.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; Flagellar basal body rod protein YP_004277806.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; Flagellar basal body protein YP_004277808.1 involved in type III protein export during flagellum assembly; Flagellar biosynthesis/type III secretory pathway ATPase YP_004277809.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; Flagellar basal body rod protein YP_004277810.1 Protein of unknown function DUF1217 YP_004277811.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Flagellar motor component YP_004277812.1 Surface presentation of antigens (SPOA) protein YP_004277813.1 Flagellar motor switch FliN, Surface presentation of antigens (SPOA) protein; Flagellar motor switch/type III secretory pathway protein YP_004277814.1 One of three proteins involved in switching the direction of the flagellar rotation; Flagellar motor switch protein YP_004277815.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; Flagellar biosynthesis pathway, component FlhB YP_004277818.1 Flagellin and related hook-associated proteins YP_004277820.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Flagellar motor protein YP_004277821.1 a periplasmic protein that interacts with and stabilizes MotB; in Rhizobium, interactions between MotB and MotC at the periplasmic surface of the motor control the energy flux or the energy coupling that drives flagellar rotation YP_004277822.1 Flagellar hook-length control protein YP_004277823.1 Lytic transglycosylase-like, catalytic; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) YP_004277824.1 CheY-like, Transcriptional regulatory protein, C terminal; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004277826.1 the hook connects flagellar basal body to the flagellar filament YP_004277827.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; Flagellar hook-associated protein YP_004277828.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; Flagellin and related hook-associated proteins YP_004277829.1 acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; Flagellar biosynthesis regulator FlaF YP_004277830.1 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; Flagellar biosynthesis regulator FlbT YP_004277831.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; Flagellar hook capping protein YP_004277832.1 FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; Flagellar biosynthesis pathway, component FliQ YP_004277833.1 membrane protein involved in the flagellar export apparatus; Flagellar biosynthesis pathway, component FlhA YP_004277834.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; Flagellar biosynthesis pathway, component FliR YP_004277839.1 glycosyl transferase WecB/TagA/CpsF; Teichoic acid biosynthesis proteins YP_004277840.1 Uncharacterized protein involved in exopolysaccharide biosynthesis YP_004277841.1 Tetrahydrofolate dehydrogenase/cyclohydrolase; 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase YP_004277842.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004277843.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004277844.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004277845.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004277846.1 glycoside hydrolase, catalytic core, Alpha amylase, catalytic domain, trehalose_treC: alpha,alpha-phosphotrehalase; glycosidases YP_004277847.1 ABC transporter related; ABC-type sugar transport systems, ATPase components YP_004277849.1 5'-Nucleotidase and apyrase; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases YP_004277850.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; Dihydroxyacid dehydratase/phosphogluconate dehydratase YP_004277851.1 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase YP_004277852.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_004277854.1 glycine/D-amino acid oxidases (deaminating) YP_004277855.1 Glutamine synthetase/guanido kinase, catalytic region, GlnA: glutamine synthetase, type I YP_004277856.1 Predicted flavoproteins YP_004277858.1 Bacterial regulatory helix-turn-helix protein, lysR family; Transcriptional regulator YP_004277860.1 Isocitrate lyase and phosphorylmutase YP_004277861.1 Protein of unknown function DUF955; Predicted transcriptional regulator YP_004277862.1 Bacterial extracellular solute-binding protein, family 1; Spermidine/putrescine-binding periplasmic protein YP_004277863.1 Spermidine/putrescine ABC transporter ATP-binding subunit; ABC-type spermidine/putrescine transport systems, ATPase components YP_004277864.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component I YP_004277865.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component II YP_004277866.1 Iron(III)-transport system permease fbpB 2; ABC-type Fe3+ transport system, permease component YP_004277867.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; FOG: PAS/PAC domain YP_004277868.1 Ppx/GppA phosphatase family YP_004277869.1 23S rRNA methylase YP_004277870.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004277871.1 Zn-dependent hydrolases, including glyoxylases YP_004277873.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; IMP dehydrogenase/GMP reductase YP_004277874.1 Protein of unknown function DUF1123; Uncharacterized protein conserved in bacteria YP_004277875.1 Alcohol dehydrogenase superfamily, zinc-containing; Zn-dependent alcohol dehydrogenases YP_004277876.1 Dienelactone hydrolase and related enzymes YP_004277877.1 molybdopterin binding domain; Molybdopterin biosynthesis enzymes YP_004277878.1 4-diphosphocytidyl-2C-methyl-D-erythritol 2- phosphate synthase YP_004277879.1 Tetratricopeptide region; FOG: TPR repeat YP_004277880.1 Terpenoid synthase, Polyprenyl synthetase; Geranylgeranyl pyrophosphate synthase YP_004277881.1 Protein of unknown function (DUF2007) YP_004277882.1 methyltransferase small; Predicted O-methyltransferase YP_004277883.1 Peptidase family S49; Periplasmic serine proteases (ClpP class) YP_004277885.1 glycine-tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase, subunit alpha YP_004277886.1 LemA family; Uncharacterized conserved protein YP_004277887.1 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta; 5-enolpyruvylshikimate-3-phosphate synthase YP_004277888.1 Predicted membrane protein YP_004277889.1 glycine-tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase, beta subunit YP_004277890.1 Protein of unknown function DUF523; Uncharacterized conserved protein YP_004277891.1 methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis protein YP_004277893.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Phosphoribosylamine-glycine ligase YP_004277894.1 Tex-like protein N-terminal domain YP_004277895.1 Cyclopropane fatty acid synthase and related methyltransferases YP_004277896.1 MltA-interacting protein MipA; Outer membrane protein V YP_004277897.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases YP_004277899.1 Protein of unknown function DUF1217 YP_004277900.1 LysR substrate binding domain; Transcriptional regulator YP_004277901.1 Protein of unknown function DUF1127 YP_004277902.1 Glutamate-cysteine ligase family 2(GCS2); Gamma-glutamylcysteine synthetase YP_004277903.1 Protein of unknown function DUF558, methyltransferase ; Uncharacterized protein conserved in bacteria YP_004277904.1 Phosphate transporter family; Phosphate/sulphate permeases YP_004277905.1 NUDIX domain; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004277906.1 Sucrose-6F-phosphate phosphohydrolase, plant and cyanobacteria; Predicted hydrolases of the HAD superfamily YP_004277907.1 glycosyl transferase, group 1 YP_004277908.1 GntR, C-terminal, FCD domain; Transcriptional regulators YP_004277909.1 Uncharacterized membrane-anchored protein conserved in bacteria YP_004277910.1 LysR substrate binding domain; Transcriptional regulator YP_004277911.1 glycolate oxidase subunit; FAD/FMN-containing dehydrogenases YP_004277912.1 FAD linked oxidase, C-terminal; FAD/FMN-containing dehydrogenases YP_004277913.1 glycolate oxidase, iron-sulphur subunit; Fe-S oxidoreductase YP_004277914.1 Outer membrane protein, beta-barrel YP_004277915.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004277916.1 DNA glycosylase; 3-methyladenine DNA glycosylase YP_004277918.1 Conserved hypothetical protein CHP00698; Predicted membrane protein YP_004277919.1 LysR substrate binding domain; Transcriptional regulator YP_004277921.1 Addiction module toxin, RelE/StbE YP_004277922.1 Ribbon-helix-helix; Predicted DNA-binding protein with an HTH domain YP_004277923.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is YP_004277924.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004277925.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase involved in histidine biosynthesis YP_004277926.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase YP_004277927.1 Surfeit locus 4-related, DoxX; Predicted membrane protein YP_004277929.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; Chaperonin GroEL (HSP60 family) YP_004277930.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans rin; Co-chaperonin GroES (HSP10) YP_004277931.1 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3; Predicted sugar phosphatases of the HAD superfamily YP_004277932.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; FAD synthase YP_004277934.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme YP_004277936.1 Cytidine and deoxycytidylate deaminase zinc-binding region; Cytosine/adenosine deaminases YP_004277937.1 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases YP_004277938.1 Conserved hypothetical protein CHP00095; N6-adenine-specific methylase YP_004277939.1 Patatin-like phospholipase; Predicted esterase of the alpha-beta hydrolase superfamily YP_004277940.1 Kef-type K+ transport systems, NAD- binding component YP_004277941.1 Peptidase U62, modulator of DNA gyrase; Predicted Zn-dependent proteases and their inactivated homologs YP_004277942.1 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004277945.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_004277946.1 haloacid dehalogenase-like hydrolase; Predicted phosphatases YP_004277947.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; Tetraacyldisaccharide-1-P 4'-kinase YP_004277948.1 Uncharacterized protein conserved in bacteria YP_004277949.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair enzyme ( ATPase) YP_004277950.1 Response regulator receiver domain; FOG: PAS/PAC domain YP_004277951.1 EAL domain, diguanylate cyclase (GGDEF) domain; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain YP_004277952.1 SMP-30/Gluconolaconase/LRE-like region; Gluconolactonase YP_004277953.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-keto-3-deoxy-6-phosphogluconate aldolase YP_004277955.1 3-oxoacyl-(acyl carrier protein) reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004277956.1 transcriptional regulator (IclR family); Transcriptional regulator YP_004277957.1 Bacterial regulatory proteins, luxR family; DNA-binding HTH domain-containing proteins YP_004277958.1 ABC transporter nucleotide-binding protein/ATPase; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004277959.1 Protein of unknown function DUF59; ATPases involved in chromosome partitioning YP_004277960.1 Magnesium and cobalt transport protein CorA; Mg2+ and Co2+ transporters YP_004277961.1 K+ potassium transporter; K+ transporter YP_004277962.1 Cell wall hydrolase, SleB; Cell wall hydrolyses involved in spore germination YP_004277963.1 ATP synthase, subunit I; Uncharacterized protein conserved in bacteria YP_004277964.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1-type ATP synthase, subunit a YP_004277965.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K YP_004277966.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel; F0F1-type ATP synthase, subunit b YP_004277967.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel; F0F1-type ATP synthase, subunit b YP_004277969.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_004277970.1 Elongator protein 3/MiaB/NifB, Radical SAM superfamily; DNA repair photolyase YP_004277971.1 glycosyltransferases involved in cell wall biogenesis YP_004277972.1 FAD linked oxidases, C-terminal domain; FAD/FMN-containing dehydrogenases YP_004277973.1 Sua5/YciO/YrdC/YwlC, yrdC domain; translation factor (SUA5) YP_004277976.1 Aromatic-ring-hydroxylating dioxygenase, subunit alpha, Rieske [2Fe-2S] domain; Phenylpropionate dioxygenase and related ring- hydroxylating dioxygenases, large terminal subunit YP_004277977.1 Ferredoxin, 2Fe-2S iron-sulfur cluster binding domain; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 YP_004277978.1 BA14K-like protein YP_004277979.1 BA14K-like protein YP_004277980.1 Mg2+ transporter protein, CorA-like; Mg2+ and Co2+ transporters YP_004277981.1 Acyl-CoA dehydrogenase/oxidase, middle, C & N-terminal; Acyl-CoA dehydrogenases YP_004277982.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Enoyl-CoA hydratase/carnithine racemase YP_004277984.1 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase YP_004277985.1 Hemolysin A, S4 domain; Predicted rRNA methylase YP_004277986.1 methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis protein YP_004277987.1 Uncharacterized conserved protein YP_004277988.1 Dimeric alpha-beta barrel; Uncharacterized conserved protein YP_004277989.1 Lambda repressor-like, DNA-binding; Predicted transcriptional regulators YP_004277991.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_004277992.1 Cupin, RmlC-type, Pirin; Pirin-related protein YP_004277993.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; Exonuclease VII small subunit YP_004277994.1 Histone deacetylase superfamily; Deacetylases, including yeast histone deacetylase and acetoin utilization protein YP_004277995.1 biotin synthesis BioY protein; Uncharacterized conserved protein YP_004277997.1 Cobalt transport protein; ABC-type cobalt transport system, permease component CbiQ and related transporters YP_004277998.1 ABC transporter related; ABC-type cobalt transport system, ATPase component YP_004277999.1 Protein of unknown function DUF1006; Uncharacterized protein conserved in bacteria YP_004278000.1 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004278001.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_004278002.1 Protein of unknown function DUF1344 YP_004278003.1 Phosphoglycerate mutase family; Broad specificity phosphatase PhoE and related phosphatases YP_004278004.1 Catalyzes a key regulatory step in fatty acid biosynthesis; Enoyl-ACP reductase (NADH) YP_004278005.1 Molecular chaperone, heat shock protein, Hsp40, DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain YP_004278007.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; Pyridoxamine-phosphate oxidase YP_004278008.1 Protein of unknown function DUF81; Predicted permeases YP_004278009.1 NTP pyrophosphohydrolase MazG-related, Rhizobiaceae-type; Predicted pyrophosphatase YP_004278010.1 Haloacid dehalogenase-like hydrolase; Predicted phosphatase/phosphohexomutase YP_004278011.1 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Lactoylglutathione lyase and related lyases YP_004278012.1 Peptidase U62, modulator of DNA gyrase; Predicted Zn-dependent proteases and their inactivated homologs YP_004278013.1 Invasion associated locus B protein; Invasion protein B, involved in pathogenesis YP_004278014.1 Heme/copper-type cytochrome/quinol oxidases, subunit 2 YP_004278015.1 cytochrome-c oxidase chain I; Heme/copper-type cytochrome/quinol oxidases, subunit 1 YP_004278016.1 converts protoheme IX and farnesyl diphosphate to heme O; Polyprenyltransferase (cytochrome oxidase assembly factor) YP_004278018.1 involved in the insertion of copper into subunit I of cytochrome C oxidase; Cytochrome oxidase assembly factor YP_004278019.1 Heme/copper-type cytochrome/quinol oxidase, subunit 3 YP_004278020.1 Protein of unknown function DUF983; Uncharacterized protein conserved in bacteria YP_004278021.1 Surfeit locus 1; Uncharacterized conserved protein YP_004278022.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; Penicillin tolerance protein YP_004278023.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase type II (protein kinase fold) YP_004278024.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; Ribonuclease HI YP_004278025.1 Stress responsive alpha-beta barrel YP_004278026.1 Quinoprotein amine dehydrogenase, beta chain-like; Predicted integral membrane proteins containing uncharacterized repeats YP_004278027.1 Peroxiredoxin YP_004278028.1 Uncharacterized protein to be involved in C-type cytochrome biogenesis YP_004278029.1 Protein of unknown function DUF179, Uncharacterized ACR, COG1678; transcriptional regulator YP_004278030.1 CsbD-like YP_004278031.1 Uncharacterised conserved protein UCP012641; Uncharacterized protein conserved in bacteria YP_004278032.1 EAL domain, GGDEF: diguanylate cyclase (GGDEF) domain; FOG: PAS/PAC domain YP_004278033.1 ribosomal-protein (S5)-alanine N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004278034.1 Insulinase (Peptidase family M16); Predicted Zn-dependent peptidases YP_004278035.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_004278038.1 Haloacid dehalogenase-like hydrolase, HAD-SF-IA-v3: HAD-superfamily hydrolase, subfamily IA, variant 3; Predicted phosphatase/phosphohexomutase YP_004278039.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004278040.1 Protein of unknown function DUF1284; Uncharacterized conserved protein YP_004278042.1 cell cycle regulated site-specific DNA-methyltransferase; DNA modification methylase YP_004278043.1 Haloacid dehalogenase-like hydrolase, HAD-SF-IA-v3: HAD-superfamily hydrolase, subfamily IA, variant 3; Predicted hydrolase (HAD superfamily) YP_004278044.1 A/G-specific DNA glycosylase YP_004278045.1 Protein of unknown function DUF1159; Uncharacterized protein conserved in bacteria YP_004278046.1 Thioredoxin-like fold; Protein-disulfide isomerase YP_004278047.1 Chromosome segregation protein SMC; Chromosome segregation ATPases YP_004278048.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Predicted ring-cleavage extradiol dioxygenase YP_004278049.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase YP_004278051.1 PliC; periplasmic lysozyme inhibitor of c-type lysozyme YP_004278052.1 Sodium:dicarboxylate symporter family; Na+/H+-dicarboxylate symporters YP_004278054.1 Metallo-beta-lactamase superfamily; Zn-dependent hydrolases, including glyoxylases YP_004278055.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Predicted dehydrogenase YP_004278059.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; GTPases - Sulfate adenylate transferase subunit 1 YP_004278060.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes YP_004278061.1 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes YP_004278062.1 Transcriptional regulator, Rrf2; Predicted transcriptional regulator YP_004278063.1 ABC transporter substrate-binding protein (sulfate); ABC-type sulfate transport system, periplasmic component YP_004278064.1 Sulphate ABC transporter permease 2; ABC-type sulfate transport system, permease component YP_004278065.1 Sulphate ABC transporter permease 2; ABC-type sulfate transport system, permease component YP_004278066.1 Sulphate transport system permease 1; ABC-type sulfate/molybdate transport systems, ATPase component YP_004278067.1 Quinone oxidoreductase , PIG3; NADPH:quinone reductase and related Zn- dependent oxidoreductases YP_004278068.1 EAL domain; FOG: EAL domain YP_004278069.1 Ribbon-helix-helix YP_004278070.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; Transcriptional regulator YP_004278071.1 catalyzes the formation of betaine from betaine aldehyde; NAD-dependent aldehyde dehydrogenases YP_004278072.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; Choline dehydrogenase and related flavoproteins YP_004278075.1 Chloride channel, voltage gated; Chloride channel protein EriC YP_004278077.1 L-asparaginase II YP_004278078.1 Glutathione S-transferase, C-terminal-like YP_004278079.1 Glutathione S-transferase, C-terminal domain YP_004278080.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004278081.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004278082.1 Predicted hydrolase of the metallo-beta- lactamase superfamily YP_004278083.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA; ATP-dependent DNA ligase YP_004278084.1 Twin-arginine translocation pathway signal; Dipeptidyl aminopeptidases/acylaminoacyl- peptidases YP_004278085.1 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; Cation transport ATPase YP_004278086.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004278087.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004278088.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004278089.1 OsmC-like protein; Organic hydroperoxide reductase YP_004278091.1 RES domain YP_004278092.1 ABC transporter related; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004278093.1 DGPF domain; Uncharacterized protein conserved in bacteria YP_004278094.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004278095.1 Protein of unknown function DUF899, thioredoxin-like; Uncharacterized protein conserved in bacteria YP_004278096.1 Protein of unknown function DUF1579 YP_004278097.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Predicted enzyme related to lactoylglutathione lyase YP_004278098.1 LysR substrate binding domain; Transcriptional regulator YP_004278099.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004278101.1 Protein of unknown function DUF853, NPT hydrolase ; helicase YP_004278104.1 HxlR-like helix-turn-helix; Predicted transcriptional regulators YP_004278105.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004278106.1 AraC protein, arabinose-binding/dimerisation; AraC-type DNA-binding domain-containing proteins YP_004278107.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004278108.1 Aldo/keto reductase family; Aldo/keto reductases, related to diketogulonate reductase YP_004278109.1 Winged helix repressor DNA-binding; Predicted transcriptional regulator YP_004278110.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004278112.1 Aminotransferase, class IV; Branched-chain amino acid aminotransferase/4- amino-4-deoxychorismate lyase YP_004278113.1 methyl-accepting chemotaxis protein (MCP) signaling domain YP_004278114.1 LysR substrate binding domain; Transcriptional regulator YP_004278115.1 Acetyltransferase (GNAT) family; Sortase and related acyltransferases YP_004278118.1 Metallophosphoesterase, Calcineurin-like phosphoesterase; Predicted phosphohydrolases YP_004278119.1 Winged helix repressor DNA-binding, HTH domain; Predicted transcriptional regulator YP_004278120.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004278121.1 Cytochrome c prime; Cytochrome c556 YP_004278122.1 Cytochrome c, monohaem; Cytochrome c, mono- and diheme variants YP_004278123.1 Cobalt transporter subunit CbtB YP_004278124.1 Cobalt transporter subunit CbtA, ; Predicted integral membrane protein YP_004278126.1 ThiJ/PfpI; intracellular protease/amidase YP_004278127.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Sortase and related acyltransferases YP_004278128.1 DNA binding; Predicted transcriptional regulators YP_004278130.1 Protein of unknown function DUF156, Uncharacterised BCR, COG1937; Uncharacterized protein conserved in bacteria YP_004278131.1 Cation efflux family, CDF: cation diffusion facilitator family transporter; Co/Zn/Cd efflux system component YP_004278133.1 ABC-type oligopeptide transport system, ATPase component YP_004278134.1 Binding-protein-dependent transport systems inner membrane component; ABC-type proline/glycine betaine transport system, permease component YP_004278135.1 Substrate-binding region of ABC-type glycine betaine transport system; ABC-type proline/glycine betaine transport systems, periplasmic components YP_004278137.1 Peptidase S9A, prolyl oligopeptidase YP_004278138.1 Protein of unknown function DUF930 YP_004278139.1 Dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004278140.1 glycoside hydrolase/deacetylase, beta/alpha-barrel, Polysaccharide deacetylase; Predicted xylanase/chitin deacetylase YP_004278141.1 methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; Adenosine deaminase YP_004278142.1 Protein of unknown function UPF0118; Predicted permease YP_004278143.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Predicted ring-cleavage extradiol dioxygenase YP_004278144.1 Universal stress protein family; Universal stress protein UspA and related nucleotide-binding proteins YP_004278145.1 Zinc finger, DksA/TraR C4-type YP_004278146.1 channel protein, hemolysin III family; Predicted membrane protein, hemolysin III homolog YP_004278147.1 Acetyltransferase (GNAT) family; Sortase and related acyltransferases YP_004278148.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004278149.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Conserved domain frequently associated with peptide methionine sulfoxide reductase YP_004278150.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit YP_004278151.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport; Multisubunit Na+/H+ antiporter, MnhB subunit YP_004278152.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Multisubunit Na+/H+ antiporter, MnhC subunit YP_004278153.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit YP_004278154.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; Multisubunit Na+/H+ antiporter, MnhE subunit YP_004278155.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; Multisubunit Na+/H+ antiporter, MnhF subunit YP_004278156.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; Multisubunit Na+/H+ antiporter, MnhG subunit YP_004278157.1 ROS/MUCR transcriptional regulator protein; Predicted transcriptional regulator YP_004278158.1 Trp repressor/replication initiator YP_004278160.1 Fe-S metabolism associated domain; SufE protein probably involved in Fe-S center assembly YP_004278162.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004278163.1 Peptidoglycan binding-like; peptidoglycan-binding domain- containing protein YP_004278164.1 Protein of unknown function DUF1491; Uncharacterized conserved protein YP_004278165.1 Uncharacterized protein conserved in bacteria YP_004278167.1 Uncharacterised conserved protein UCP010244, integral membrane protein; Predicted integral membrane protein YP_004278168.1 Protein of unknown function DUF1214; Uncharacterized conserved protein YP_004278169.1 Peptidase family M20/M25/M40; Acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases YP_004278170.1 Lysine exporter protein (LYSE/YGGA); Lysine efflux permease YP_004278171.1 Bacterial regulatory helix-turn-helix protein, lysR family; Transcriptional regulator YP_004278172.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Lactoylglutathione lyase and related lyases YP_004278173.1 Penicillin-binding protein 1A; Membrane carboxypeptidase (penicillin-binding protein) YP_004278175.1 Uncharacterised conserved protein UCP006173; Uncharacterized conserved protein YP_004278176.1 Beta-lactamase-type transpeptidase fold, Penicillin binding protein transpeptidase domain YP_004278177.1 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4- benzoquinol methylase YP_004278178.1 CueR: Cu(I)-responsive transcriptional regulator; Predicted transcriptional regulators YP_004278180.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004278182.1 glycosyl hydrolases family 32 N terminal; Beta-fructosidases (levanase/invertase) YP_004278183.1 HWE histidine kinase; Signal transduction histidine kinase YP_004278184.1 Protein of unknown function UPF0061; Uncharacterized conserved protein YP_004278185.1 Saccharopine dehydrogenase and related proteins YP_004278186.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004278187.1 Helix-turn-helix, HxlR type; Predicted transcriptional regulators YP_004278188.1 NmrA-like; Predicted nucleoside-diphosphate-sugar epimerases YP_004278189.1 Uncharacterised conserved protein UCP007542; Predicted membrane protein YP_004278191.1 Terminase-like family; Uncharacterized conserved protein YP_004278192.1 glycoside hydrolase, family 19, catalytic YP_004278193.1 Stress responsive alpha-beta barrel YP_004278194.1 Phage portal protein; Phage-related protein YP_004278196.1 Peptidase U35, phage prohead HK97, Caudovirus prohead protease; Phage head maturation protease YP_004278197.1 Phage major capsid protein, HK97; Predicted phage phi-C31 gp36 major capsid-like protein YP_004278198.1 Phage conserved hypothetical protein, phiE125 gp8 YP_004278199.1 gp16_SPP1: phage head-tail adaptor, ; Bacteriophage head-tail adaptor YP_004278201.1 Major facilitator superfamily YP_004278202.1 Phage major tail protein, TP901-1; Predicted secreted protein YP_004278204.1 Conserved hypothetical protein CHP02216, phage YP_004278206.1 Conserved hypothetical protein CHP02217; Uncharacterized conserved protein YP_004278207.1 Phage conserved hypothetical protein BR0599; Uncharacterized conserved protein YP_004278208.1 phage cell wall peptidase, NlpC/P60; Cell wall-associated hydrolases (invasion- associated proteins) YP_004278209.1 Acyl carrier protein-like YP_004278212.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004278213.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004278214.1 Surface antigen YP_004278215.1 Tetratricopeptide-like helical; Cytochrome c biogenesis factor YP_004278216.1 CcmE/CycJ protein YP_004278217.1 Cytochrome c-type biogenesis protein CcmF; Cytochrome c biogenesis factor YP_004278218.1 Cytochrome C biogenesis protein; Uncharacterized protein involved in biosynthesis of c-type cytochromes YP_004278219.1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain YP_004278220.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004278221.1 two component sensor kinase; Signal transduction histidine kinase YP_004278222.1 thiol-disulphide oxidoreductase DCC, Protein of unknown function, DUF393; Predicted thiol-disulfide oxidoreductase YP_004278223.1 MltA-interacting protein MipA; Outer membrane protein V YP_004278224.1 Glutamine synthetase adenylyltransferase YP_004278225.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; FOG: PAS/PAC domain YP_004278226.1 Carboxymuconolactone decarboxylase family; Uncharacterized homolog of gamma- carboxymuconolactone decarboxylase subunit YP_004278228.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004278230.1 Phage SPO1 DNA polymerase-related protein; Uracil-DNA glycosylase YP_004278231.1 Heat shock protein Hsp70; Molecular chaperone YP_004278232.1 diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004278233.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004278234.1 cation diffusion facilitator family transporter; Predicted Co/Zn/Cd cation transporters YP_004278235.1 Protein of unknown function (DUF1130); Uncharacterized conserved protein YP_004278237.1 Electron transfer flavoprotein-ubiquinone oxidoreductase; Dehydrogenases (flavoproteins) YP_004278238.1 Pentapeptide repeat; Uncharacterized low-complexity proteins YP_004278239.1 Alcohol dehydrogenase GroES-like domain; NADPH:quinone reductase and related Zn- dependent oxidoreductases YP_004278240.1 Helix-turn-helix, HxlR type; Predicted transcriptional regulators YP_004278241.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; Uncharacterized bacitracin resistance protein YP_004278242.1 RecF like; Predicted ATPase YP_004278244.1 Divalent cation transporter; Mg/Co/Ni transporter MgtE (contains CBS domain) YP_004278245.1 Major facilitator superfamily; Arabinose efflux permease YP_004278246.1 Diacylglycerol kinase catalytic domain (presumed); Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase YP_004278247.1 Pyridoxal phosphate-dependent transferase, major region, Aminotransferase class-III YP_004278248.1 OsmC-like protein; Predicted redox protein, regulator of disulfide bond formation YP_004278249.1 PilT protein, N-terminal, PIN domain; Predicted nucleic acid-binding protein, contains PIN domain YP_004278251.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; Nucleoside phosphorylase YP_004278254.1 2-phosphoglycerate kinase YP_004278255.1 Uncharacterized protein conserved in bacteria YP_004278256.1 Sel1-like YP_004278257.1 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase YP_004278260.1 NAD(P)H-nitrite reductase YP_004278265.1 Porin, alpha proteobacteria type YP_004278266.1 Porin, alpha proteobacteria type YP_004278267.1 Lytic transglycosylase-like, catalytic; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) YP_004278268.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; Dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004278269.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; tmRNA-binding protein YP_004278270.1 methyl-accepting chemotaxis protein (MCP) signaling domain YP_004278271.1 Protein of unknown function DUF88; Uncharacterized conserved protein YP_004278272.1 Promotes RNA polymerase assembly. Latches the N-and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and subunit alphas; DNA-directed RNA polymerase, subunit K/omega YP_004278273.1 Guanosine polyphosphate pyrophosphohydrolases/synthetases YP_004278275.1 Uncharacterized protein conserved in bacteria YP_004278276.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; Phosphopantetheinyl transferase (holo-ACP synthase) YP_004278277.1 Peptidase S24, S26A, S26B and S26C; Signal peptidase I YP_004278278.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; dsRNA-specific ribonuclease YP_004278279.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTPase YP_004278280.1 Cyclic nucleotide-binding domain; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_004278281.1 CheY-like; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004278282.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; Recombinational DNA repair protein (RecF pathway) YP_004278283.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004278284.1 methyltransferase type 11; SAM-dependent methyltransferases YP_004278285.1 Pyruvate kinase, beta-barrel-like, MOSC domain; Uncharacterized Fe-S protein YP_004278286.1 Metal-dependent phosphohydrolase, HD region; Predicted HD superfamily hydrolase YP_004278287.1 Uncharacterised conserved protein UCP035905, membrane protein; Predicted membrane protein YP_004278288.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004278289.1 NMT1/THI5 like; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004278290.1 ABC transporter related; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004278291.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004278292.1 Calycin, YodA; Predicted periplasmic or secreted protein YP_004278293.1 MscS Mechanosensitive ion channel; Small-conductance mechanosensitive channel YP_004278294.1 Predicted protein tyrosine phosphatase YP_004278295.1 Predicted hydrolases of HD superfamily YP_004278296.1 glycine cleavage T-protein, C-terminal barrel, Aminomethyltransferase folate-binding domain; Predicted aminomethyltransferase related to GcvT YP_004278299.1 Conserved hypothetical protein CHP02301; Predicted secreted protein YP_004278300.1 NUDIX domain YP_004278301.1 Protein of unknown function UPF0060; Uncharacterized conserved protein YP_004278302.1 Protein of unknown function DUF159; Uncharacterized conserved protein YP_004278303.1 GGDEF: diguanylate cyclase (GGDEF) domain; Response regulator containing a CheY-like receiver domain and a GGDEF domain YP_004278306.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_004278307.1 ABC transporter, transmembrane region, type 1; ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components YP_004278308.1 Peptidoglycan-binding LysM; Uncharacterized protein containing LysM domain YP_004278309.1 Conserved hypothetical protein CHP00730; Predicted Rossmann fold nucleotide-binding protein YP_004278310.1 Beta-lactamase-type transpeptidase fold, Penicillin binding protein transpeptidase domain; Cell division protein FtsI/penicillin-binding protein 2 YP_004278311.1 Predicted permeases YP_004278312.1 Peptidase S33, proline iminopeptidase 1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004278313.1 Glutathione-dependent formaldehyde-activating enzyme; Uncharacterized conserved protein YP_004278314.1 Glutathione-dependent formaldehyde-activating enzyme; Uncharacterized conserved protein YP_004278315.1 Glutathione-dependent formaldehyde-activating enzyme; Uncharacterized conserved protein YP_004278316.1 Protein of unknown function (DUF559); Uncharacterized protein conserved in bacteria YP_004278317.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_004278318.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004278319.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; Glutamine phosphoribosylpyrophosphate amidotransferase YP_004278320.1 Uncharacterized membrane protein, required for colicin V production YP_004278321.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; Predicted ATP-dependent serine protease YP_004278322.1 addiction module antidote protein, CC2985; Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain YP_004278324.1 AraC protein, arabinose-binding/dimerisation; AraC-type DNA-binding domain-containing proteins YP_004278325.1 azaleucine resistance protein AzlC; Predicted branched-chain amino acid permease (azaleucine resistance) YP_004278326.1 Branched-chain amino acid transport protein (AzlD) YP_004278327.1 unwinds double stranded DNA YP_004278328.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004278329.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004278330.1 Secretion protein HlyD; Multidrug resistance efflux pump YP_004278331.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; Ribosomal protein L9 YP_004278333.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; Ribosomal protein S18 YP_004278334.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; Ribosomal protein S6 YP_004278336.1 Aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004278337.1 Membrane protease subunits, stomatin/prohibitin homologs YP_004278338.1 catalyzes the formation of 3-hydroxyacyl-ACP from 3-keto-acyl-ACP; in the rhizobia this protein interacts with NodF to allow for the synthesis of highly polyunsaturated fatty acids necessary for nodulation; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004278339.1 carries the fatty acid chain in fatty acid biosynthesis YP_004278340.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase YP_004278342.1 Predicted periplasmic solute-binding protein YP_004278343.1 Conserved hypothetical protein CHP00255, Domain of unknown function (DUF1732); Uncharacterized stress-induced protein YP_004278344.1 Essential for recycling GMP and indirectly, cGMP YP_004278345.1 Phospholipase/Carboxylesterase; Predicted esterase YP_004278346.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; Dimethyladenosine transferase (rRNA methylation) YP_004278347.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); Pyridoxal phosphate biosynthesis protein YP_004278348.1 SurA N-terminal domain; Parvulin-like peptidyl-prolyl isomerase YP_004278349.1 Organic solvent tolerance protein OstA YP_004278350.1 Predicted permease YjgP/YjgQ family; Predicted permeases YP_004278351.1 Predicted permease YjgP/YjgQ family; Predicted permeases YP_004278352.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; Leucyl aminopeptidase YP_004278353.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III, chi subunit YP_004278354.1 GGDEF: diguanylate cyclase (GGDEF) domain; c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) YP_004278355.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004278356.1 EAL domain; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain YP_004278357.1 ABC transporter related; ATPase components of ABC transporters with duplicated ATPase domains YP_004278358.1 GGDEF: diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004278359.1 Glutathione S-transferase, C-terminal-like; Predicted glutathione S-transferase YP_004278360.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_004278362.1 Protein of unknown function DUF1470; Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding YP_004278363.1 Bacterial inner-membrane translocator; Branched-chain amino acid ABC-type transport system, permease components YP_004278364.1 Molybdopterin biosynthesis MoaE YP_004278365.1 Molybdopterin converting factor, small subunit YP_004278366.1 CDP-alcohol phosphatidyltransferase; Phosphatidylglycerophosphate synthase YP_004278367.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; Nuclease subunit of the excinuclease complex YP_004278368.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004278369.1 Outer membrane protein, OmpA-like, transmembrane region; Opacity protein and related surface antigens YP_004278370.1 Glutathione S-transferase, C-terminal-like YP_004278371.1 Ribonuclease T2 family; Ribonuclease I YP_004278372.1 Predicted integral membrane protein YP_004278373.1 Protein of unknown function DUF519; Protein involved in catabolism of external DNA YP_004278374.1 Anaerobic dehydrogenases, typically selenocysteine-containing YP_004278375.1 NUDIX; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004278376.1 NUDIX; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004278377.1 Peptidase A26, omptin, Omptin family; Outer membrane protease YP_004278378.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; Folate-dependent phosphoribosylglycinamide formyltransferase PurN YP_004278379.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; Phosphoribosylaminoimidazole (AIR) synthetase YP_004278380.1 Protein of unknown function UPF0118, Domain of unknown function DUF20; Predicted permease YP_004278381.1 ATPase involved in DNA replication initiation YP_004278382.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_004278384.1 Trimeric LpxA-like; Acetyltransferase (isoleucine patch superfamily) YP_004278387.1 Uncharacterized protein conserved in bacteria YP_004278388.1 Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylate cyclase, family 3 (some proteins contain HAMP domain) YP_004278391.1 Arabinose efflux permease YP_004278392.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_004278393.1 Inner membrane protein CreD; Inner membrane protein involved in colicin E2 resistance YP_004278394.1 Sulfate transporter family; Sulfate permease and related transporters (MFS superfamily) YP_004278396.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit YP_004278397.1 SpoVT/AbrB-like, transcription regulator YP_004278398.1 Arginine-tRNA-protein transferase, C terminus; arginyl-tRNA:protein arginylyltransferase YP_004278399.1 RDD; Predicted membrane protein/domain YP_004278400.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_004278402.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004278403.1 Peptidoglycan binding-like; Uncharacterized protein conserved in bacteria YP_004278404.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; glycine/serine hydroxymethyltransferase YP_004278405.1 Ribonucleotide reductase regulator NrdR-like; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains YP_004278406.1 Riboflavin biosynthesis protein RibD, Cytidine and deoxycytidylate deaminase zinc-binding region; Pyrimidine reductase, riboflavin biosynthesis YP_004278407.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_004278408.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004278409.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; Riboflavin synthase beta-chain YP_004278410.1 Regulates rRNA biosynthesis by transcriptional antitermination; Transcription termination factor YP_004278411.1 Major facilitator superfamily MFS-1; Arabinose efflux permease YP_004278412.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; Inorganic pyrophosphatase YP_004278413.1 SmpA / OmlA family; Small protein A (tmRNA-binding) YP_004278414.1 Uncharacterised conserved protein UCP032079; Uncharacterized conserved protein YP_004278416.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; Fatty acid/phospholipid biosynthesis enzyme YP_004278417.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase III YP_004278418.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; Bacterial nucleoid DNA-binding protein YP_004278419.1 DNA binding; Predicted transcriptional regulators YP_004278420.1 Micrococcal nuclease (thermonuclease) homologs YP_004278421.1 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter, E1-E2 ATPase; Cation transport ATPase YP_004278422.1 naphthalene 1,2-dioxygenase; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases YP_004278423.1 Cu(I)-responsive transcriptional regulator, MerR, DNA binding; Predicted transcriptional regulators YP_004278424.1 nickel ABC transporter, permease subunit NikB; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004278425.1 nickel ABC transporter, permease subunit NikC; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004278426.1 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004278427.1 ABC-type oligopeptide transport system, ATPase component YP_004278428.1 nickel ABC transporter, periplasmic nickel-binding protein; ABC-type dipeptide transport system, periplasmic component YP_004278429.1 Heavy metal transport/detoxification protein YP_004278430.1 Cation transport protein, potassium uptake protein, TrkH family; Trk-type K+ transport systems, membrane components YP_004278431.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_004278432.1 Uncharacterized conserved protein YP_004278433.1 diguanylate cyclase (GGDEF) domain; Response regulator containing a CheY-like receiver domain and a GGDEF domain YP_004278434.1 Flavodoxin-like fold; Acyl carrier protein phosphodiesterase YP_004278435.1 LysR substrate binding domain; Transcriptional regulator YP_004278437.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases YP_004278438.1 Type IV pilus assembly PilZ YP_004278439.1 Protein of unknown function DUF1203 YP_004278441.1 Dihydrofolate reductase YP_004278442.1 Rhodanese-related sulfurtransferase YP_004278443.1 Alanyl-tRNA synthetase, class IIc; Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain YP_004278444.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_004278446.1 DNA photolyase, FAD-binding, FAD binding domain of DNA photolyase; Deoxyribodipyrimidine photolyase YP_004278447.1 Protein of unknown function DUF982 YP_004278448.1 methylated DNA-protein cysteine methyltransferase YP_004278449.1 Conserved hypothetical protein CHP02594 YP_004278453.1 Exopolysaccharide synthesis, ExoD; Uncharacterized ABC-type transport system, permease components YP_004278455.1 Predicted membrane protein YP_004278456.1 Protein-tyrosine phosphatase, Tyr-specific/dual-specificity type; Protein tyrosine/serine phosphatase YP_004278458.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004278459.1 Bacterial transport system permease; ABC-type Fe3+-siderophore transport system, permease component YP_004278460.1 Fe(III) dicitrate ABC transporter ATP-binding protein; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components YP_004278461.1 Copper binding proteins, plastocyanin/azurin family; Plastocyanin YP_004278462.1 Ferritin-like domain; Ferritin-like protein YP_004278465.1 Protein of unknown function (DUF1269); Predicted membrane protein YP_004278469.1 Bacterial sugar transferase; Sugar transferases involved in lipopolysaccharide synthesis YP_004278470.1 glycosyl transferases group 1; glycosyltransferase YP_004278471.1 Polysaccharide biosynthesis/export protein; Periplasmic protein involved in polysaccharide export YP_004278472.1 Lipopolysaccharide biosynthesis; Uncharacterized protein involved in exopolysaccharide biosynthesis YP_004278473.1 exopolysaccharide transport protein family; Uncharacterized protein involved in exopolysaccharide biosynthesis YP_004278474.1 Protein involved in cellulose biosynthesis (CelD) YP_004278476.1 Cytochrome oxidase assembly protein; Uncharacterized protein required for cytochrome oxidase assembly YP_004278477.1 Aminoglycoside/hydroxyurea antibiotic resistance kinase; Streptomycin 6-kinase YP_004278478.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; Acetylglutamate semialdehyde dehydrogenase YP_004278479.1 catalyzes the formation of putrescine from agmatine; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family YP_004278480.1 forms a direct contact with the tRNA during translation; Ribosomal protein S9 YP_004278481.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; Ribosomal protein L13 YP_004278482.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004278484.1 Predicted CoA-binding protein YP_004278485.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine sulfhydrylase YP_004278486.1 Cupin, RmlC-type, Protein of unknown function (DUF861); Predicted enzyme of the cupin superfamily YP_004278487.1 Cytochrome P450 YP_004278488.1 diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004278489.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; Protease subunit of ATP-dependent Clp proteases YP_004278490.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease Clp, ATPase subunit YP_004278492.1 Lon protease (S16) C-terminal proteolytic domain; ATP-dependent Lon protease, bacterial type YP_004278493.1 Histone-like bacterial DNA-binding protein; Bacterial nucleoid DNA-binding protein YP_004278496.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase subunit 3 (chain A) YP_004278497.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases YP_004278498.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase 27 kD subunit YP_004278499.1 Glutathione-dependent formaldehyde-activating enzyme; Uncharacterized conserved protein YP_004278500.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase 49 kD subunit 7 YP_004278502.1 catalyzes the transfer of electrons from NADH to ubiquinone; NADH:ubiquinone oxidoreductase 24 kD subunit YP_004278503.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit YP_004278504.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) YP_004278505.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase subunit 1 (chain H) YP_004278506.1 Catalyzes the transfer of electrons from NADH to quinone; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) YP_004278507.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase subunit 6 (chain J) YP_004278508.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) YP_004278509.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit YP_004278510.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase subunit 4 (chain M) YP_004278511.1 Catalyzes the transfer of electrons from NADH to quinone; NADH:ubiquinone oxidoreductase subunit 2 (chain N) YP_004278512.1 Biotin/lipoate A/B protein ligase family; Biotin-(acetyl-CoA carboxylase) ligase YP_004278513.1 Metallo-beta-lactamase superfamily; Predicted hydrolase of the metallo-beta- lactamase superfamily YP_004278514.1 Protein of unknown function DUF1467; Predicted secreted protein YP_004278515.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_004278516.1 Lipoprotein releasing system, transmembrane protein, LolC/E family; ABC-type transport system, involved in lipoprotein release, permease component YP_004278517.1 ABC transporter; ABC-type antimicrobial peptide transport system, ATPase component YP_004278518.1 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III, subunit alpha YP_004278519.1 ErfK/YbiS/YcfS/YnhG; peptidoglycan-binding domain- containing protein YP_004278520.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Nucleotidyltransferase/DNA polymerase involved in DNA repair YP_004278522.1 CheY-like, Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004278523.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Response regulator containing a CheY-like receiver domain and a GGDEF domain YP_004278524.1 Ribosomal protein L33 YP_004278525.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004278526.1 NUDIX domain; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004278527.1 Protein of unknown function DUF983; Uncharacterized protein conserved in bacteria YP_004278528.1 Exoribonuclease R YP_004278529.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; Topoisomerase IA YP_004278531.1 SMF protein, SMF family; Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake YP_004278532.1 Protein of unknown function DUF205; Predicted membrane protein YP_004278533.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Dihydroorotase and related cyclic amidohydrolases YP_004278534.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L-aspartate in pyrimidine biosynthesis; Aspartate carbamoyltransferase, catalytic chain YP_004278535.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004278536.1 GCN5-related N-acetyltransferase; Acetyltransferases YP_004278537.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004278540.1 Polynucleotidyl transferase, Ribonuclease H fold, Uncharacterised protein family (UPF0081); Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) YP_004278541.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; Predicted Zn-dependent hydrolases of the beta- lactamase fold YP_004278542.1 Glu-tRNAGln amidotransferase, C subunit, amidotransferase, C subunit; Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit YP_004278543.1 Amidase signature enzyme, glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases YP_004278544.1 Uncharacterized protein conserved in bacteria YP_004278545.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases YP_004278546.1 Protein of unknown function DUF1294; Predicted membrane protein YP_004278547.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) YP_004278548.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases YP_004278549.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases YP_004278550.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; NADH:ubiquinone oxidoreductase 17.2 kD subunit YP_004278551.1 Uncharacterized protein conserved in bacteria YP_004278552.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; Leu/Phe-tRNA-protein transferase YP_004278553.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_004278554.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolismn; Biotin carboxyl carrier protein YP_004278555.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase II YP_004278556.1 DSBA-like thioredoxin domain, outer membrane protein; Protein-disulfide isomerase YP_004278557.1 Pyridoxal phosphate-dependent transferase, major region, Aminotransferase class I and II; Aspartate/tyrosine/aromatic aminotransferase YP_004278558.1 Bacterial regulatory protein, ArsR; Predicted transcriptional regulators YP_004278559.1 NIPSNAP YP_004278560.1 Dimeric alpha-beta barrel, Antibiotic biosynthesis monooxygenase; Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides YP_004278561.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004278562.1 RNaseEG: ribonuclease, Rne/Rng family; Ribonucleases G and E YP_004278564.1 Cell wall hydrolase/autolysin, catalytic, N-acetylmuramoyl-L-alanine amidase YP_004278565.1 Penicillin-binding protein 1A, Transglycosylase; Membrane carboxypeptidase/penicillin-binding protein YP_004278566.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA; Protein chain release factor B YP_004278567.1 Isochorismatase hydrolase; Amidases related to nicotinamidase YP_004278569.1 catalyzes the phosphorylation of NAD to NADP; NAD kinase YP_004278570.1 Phenazine biosynthesis PhzC/PhzF protein; Predicted epimerase, PhzC/PhzF homolog YP_004278572.1 Hpt domain YP_004278573.1 Beta-grasp fold, ferredoxin-type; Ferredoxin YP_004278574.1 Protein of unknown function DUF922, bacterial; Predicted secreted Zn-dependent protease YP_004278575.1 Dihydropteroate synthase-like, Pterin binding enzyme; Dihydropteroate synthase and related enzymes YP_004278577.1 7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_004278579.1 Family of unknown function (DUF697); Predicted membrane protein YP_004278580.1 Protein of unknown function DUF463, YcjX-like protein; Predicted ATPase YP_004278581.1 Phosphoglycerate mutase family; Phosphohistidine phosphatase SixA YP_004278582.1 RNA polymerase-binding, DksA, Prokaryotic dksA/traR C4-type zinc finger YP_004278585.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; FOG: PAS/PAC domain YP_004278587.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; Uncharacterized conserved protein YP_004278588.1 ATPases with chaperone activity, ATP-binding subunit YP_004278589.1 AzlC-like; Predicted branched-chain amino acid permease (azaleucine resistance) YP_004278593.1 Bacterial regulatory helix-turn-helix protein, lysR family; Transcriptional regulator YP_004278594.1 Domain of unknown function (DUF1989); Uncharacterized conserved protein YP_004278595.1 Histidine triad-like motif; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases YP_004278596.1 Protein of unknown function DUF482; Uncharacterized protein conserved in bacteria YP_004278597.1 glycerophosphoryl diester phosphodiesterase family YP_004278598.1 Endoribonuclease L-PSP/chorismate mutase-like; translation initiation inhibitor, yjgF family YP_004278599.1 Protein of unknown function DUF1849 YP_004278601.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; Ribosomal protein S2 YP_004278602.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; Translation elongation factor Ts YP_004278603.1 Catalyzes the phosphorylation of UMP to UDP YP_004278604.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally YP_004278606.1 CDP-diglyceride synthetase YP_004278607.1 Peptidase M50, membrane-associated zinc metallopeptidase; Predicted membrane-associated Zn-dependent proteases 1 YP_004278608.1 Bacterial surface antigen (D15), Surface antigen; Outer membrane protein/protective antigen OMA87 YP_004278609.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_004278610.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases YP_004278611.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; Acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase YP_004278612.1 Protein of unknown function DUF1009; Uncharacterized protein conserved in bacteria YP_004278613.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; Lipid A disaccharide synthetase YP_004278614.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Citrate synthase YP_004278615.1 ComEC/Rec2-related protein, Competence protein; Predicted membrane metal-binding protein YP_004278616.1 Glutathione S-transferase, C-terminal-like YP_004278618.1 Represses a number of genes involved in the response to DNA damage; SOS-response transcriptional repressors (RecA- mediated autopeptidases) YP_004278620.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 3-deoxy-D-manno-octulosonic acid (KDO) 8- phosphate synthase YP_004278622.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_004278624.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, subunit alpha YP_004278625.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit YP_004278626.1 Dihydrolipoamide acetyltransferase, long form, 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes YP_004278627.1 Esterase, SGNH hydrolase-type, GDSL-like Lipase/Acylhydrolase; Lysophospholipase L1 and related esterases YP_004278628.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes YP_004278629.1 Transglycosylase-associated protein YP_004278630.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; Lipoate synthase YP_004278631.1 Protein of unknown function DUF6, transmembrane YP_004278632.1 Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type DNA-binding domain-containing proteins YP_004278634.1 Adenylate kinase and related kinases YP_004278635.1 Polyketide cyclase / dehydrase and lipid transport; Oligoketide cyclase/lipid transport protein YP_004278636.1 Competence-damaged protein; Uncharacterized protein (competence- and mitomycin-induced) YP_004278637.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004278638.1 TIM-barrel protein, nifR3 family; tRNA-dihydrouridine synthase YP_004278639.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase, nitrogen specific YP_004278640.1 Nitrogen regulation protein NR(I); Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains YP_004278641.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation YP_004278642.1 RNA polymerase sigma factor 54, interaction; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains YP_004278643.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; K+ transport systems, NAD-binding component YP_004278644.1 Stimulates the elongation of poly(A) tails; Uncharacterized host factor I protein YP_004278645.1 GTP-binding protein, HSR1-related, GTPase of unknown function; GTPases YP_004278646.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; Predicted pyrophosphatase YP_004278647.1 CMP/dCMP deaminase, zinc-binding; Cytosine/adenosine deaminases YP_004278648.1 Uroporphyrin-III C-methyltransferase, C-terminal, Tetrapyrrole (Corrin/Porphyrin) methylases; Uroporphyrinogen-III methylase YP_004278650.1 Nitrite and sulphite reductase 4Fe-4S domain; Sulfite reductase, beta subunit (hemoprotein) YP_004278651.1 Bacterial protein of unknown function (DUF934); Uncharacterized protein conserved in bacteria YP_004278652.1 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 YP_004278653.1 Major facilitator superfamily MFS-1; Permeases of the major facilitator superfamily YP_004278655.1 Endonuclease/Exonuclease/phosphatase family; Exonuclease III YP_004278656.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine cleavage system protein P (pyridoxal- binding), C-terminal domain YP_004278657.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system H protein (lipoate- binding) YP_004278658.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system T protein (aminomethyltransferase) YP_004278661.1 Protein of unknown function DUF461; Uncharacterized protein conserved in bacteria YP_004278662.1 Cupredoxin; Uncharacterized copper-binding protein YP_004278664.1 Camphor resistance CrcB protein; Integral membrane protein possibly involved in chromosome condensation YP_004278665.1 RNA pseudouridylate synthase; Pseudouridylate synthases, 23S RNA-specific YP_004278666.1 haloacid dehalogenase-like hydrolase; Predicted phosphatases YP_004278667.1 ATP12 chaperone protein; Chaperone required for the assembly of the mitochondrial F1-ATPase YP_004278669.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004278670.1 Endoribonuclease L-PSP/chorismate mutase-like; translation initiation inhibitor, yjgF family YP_004278671.1 S-formylglutathione hydrolase, esterase; Predicted esterase YP_004278672.1 Protein of unknown function DUF1345; Predicted membrane protein YP_004278673.1 Protein of unknown function DUF188, Uncharacterized BCR, YaiI/YqxD family COG1671; Uncharacterized protein conserved in bacteria YP_004278675.1 Thioredoxin-like fold, AhpC/TSA family; Peroxiredoxin YP_004278677.1 Glutathione S-transferase, C-terminal-like YP_004278678.1 FMN-binding split barrel, related, Pyridoxamine 5'-phosphate oxidase; Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase YP_004278679.1 Cytochrome b561 family YP_004278680.1 Predicted transmembrane transcriptional regulator (anti-sigma factor) YP_004278681.1 RNA polymerase sigma factor, sigma-70 family; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004278682.1 Uncharacterised conserved lipoprotein, Secreted repeat of unknown function; Uncharacterized protein conserved in bacteria YP_004278683.1 Lipid/polyisoprenoid-binding, YceI-like; Uncharacterized conserved protein YP_004278684.1 Integrase, catalytic core; Transposase and inactivated derivatives YP_004278686.1 LysR substrate binding domain; Transcriptional regulator YP_004278687.1 Protein of unknown function DUF453; Uncharacterized protein conserved in bacteria YP_004278688.1 ABC transporter, substrate-binding protein, aliphatic; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004278689.1 ABC transporter related; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004278690.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004278691.1 Histidine kinase, sensory_box: PAS domain S-box; Signal transduction histidine kinase YP_004278692.1 CheY-like; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004278693.1 HWE histidine kinase, sensory_box: PAS domain S-box YP_004278694.1 CheY-like, Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004278695.1 Uncharacterized protein conserved in bacteria YP_004278696.1 Cytochrome c, class IA/ IB YP_004278698.1 Glucose-methanol-choline oxidoreductase, N-terminal; Choline dehydrogenase and related flavoproteins YP_004278699.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004278700.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004278701.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004278702.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004278703.1 Branched-chain amino acid transport system / permease component; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004278704.1 Branched-chain amino acid transport system / permease component; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004278705.1 D-xylose ABC transporter ATP-binding protein; ABC-type sugar transport system, ATPase component YP_004278706.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004278707.1 Ribonuclease HI YP_004278708.1 RDD YP_004278709.1 methyltransferase domain; SAM-dependent methyltransferases YP_004278710.1 Chloride channel, voltage gated; Chloride channel protein EriC YP_004278711.1 Metallo-beta-lactamase superfamily; Metal-dependent hydrolases of the beta- lactamase superfamily I YP_004278712.1 Deoxyribonuclease, TatD Mg-dependent; Mg-dependent DNase YP_004278713.1 methionine-tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_004278714.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; ATPase involved in DNA replication YP_004278715.1 thymydilate kinase YP_004278716.1 Beta-lactamase-type transpeptidase fold, penicillin binding protein YP_004278717.1 Rare lipoprotein A -like double-psi beta-barrel; Lipoproteins YP_004278723.1 Beta-lactamase-type transpeptidase fold, penicillin-binding protein YP_004278725.1 negatively supercoils closed circular double-stranded DNA; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit YP_004278726.1 Multiple antibiotic resistance (MarC)-related proteins; Multiple antibiotic transporter YP_004278727.1 HPP family; CBS-domain-containing membrane protein YP_004278728.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_004278729.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; Excinuclease ATPase subunit YP_004278730.1 Protein of unknown function DUF72; Uncharacterized conserved protein YP_004278731.1 Dihydrouridine synthase, DuS; tRNA-dihydrouridine synthase YP_004278732.1 DNA breaking-rejoining enzyme, catalytic core; Integrase YP_004278735.1 Lambda repressor-like, DNA-binding YP_004278736.1 DNA breaking-rejoining enzyme, catalytic core; Integrase YP_004278739.1 Protein of unknown function DUF159; Uncharacterized conserved protein YP_004278745.1 glycoside hydrolase, family 24, peptidoglycan binding domain; Phage-related lysozyme (muraminidase) YP_004278747.1 Carbohydrate-binding family V/XII YP_004278749.1 Phage-related protein, tail component YP_004278754.1 Protein of unknown function DUF892; Uncharacterized protein conserved in bacteria YP_004278755.1 Phage-related minor tail protein YP_004278758.1 Predicted secreted protein YP_004278760.1 Phage protein, HK97, gp10 YP_004278761.1 Conserved hypothetical protein CHP01563 YP_004278765.1 Phage major capsid protein, HK97 YP_004278766.1 Peptidase family S49, SppA_dom: signal peptide peptidase SppA, 36K type; Periplasmic serine proteases (ClpP class) YP_004278767.1 Phage portal protein; Phage-related protein YP_004278768.1 Phage Terminase; Phage terminase-like protein, large subunit YP_004278770.1 Restriction endonuclease YP_004278773.1 VRR-NUC YP_004278777.1 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen YP_004278779.1 Bifunctional DNA primase/polymerase, N-terminal; RecA-family ATPase YP_004278781.1 Fumarylacetoacetate (FAA) hydrolase family, HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene- 1,7-dioic acid hydratase (catechol pathway) YP_004278782.1 Trimeric LpxA-like, phenylacetic acid degradation protein PaaY; Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily YP_004278783.1 zinc uptake regulation protein,, Ferric-uptake regulator; Fe2+/Zn2+ uptake regulation proteins YP_004278784.1 ABC transporter transmembrane protein (zinc); ABC-type Mn2+/Zn2+ transport systems, permease components YP_004278785.1 ABC transporter nucleotide-binding protein/ATPase (zinc); ABC-type Mn/Zn transport systems, ATPase component YP_004278786.1 ABC transporter substrate-binding protein (zinc); ABC-type Zn2+ transport system, periplasmic component/surface adhesin YP_004278787.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004278788.1 glycoside hydrolase, catalytic core; Beta-galactosidase/beta-glucuronidase YP_004278789.1 Aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004278790.1 Predicted integral membrane protein YP_004278791.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_004278792.1 Cytochrome oxidase maturation protein cbb3-type; Uncharacterized protein, possibly involved in nitrogen fixation YP_004278793.1 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter, E1-E2 type cation ATPase FixI; Cation transport ATPase YP_004278794.1 FixH; Predicted integral membrane protein linked to a cation pump YP_004278795.1 Cytochrome c oxidase cbb3 type, accessory protein FixG; Polyferredoxin YP_004278797.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Predicted enzyme related to lactoylglutathione lyase YP_004278798.1 Cytochrome c oxidase cbb3-type, subunit III; Cytochrome c, mono- and diheme variants YP_004278799.1 Cbb3-type cytochrome oxidase component FixQ; Cbb3-type cytochrome oxidase, subunit 3 YP_004278800.1 Cytochrome C oxidase, mono-heme subunit/FixO; Cbb3-type cytochrome oxidase, cytochrome c subunit YP_004278801.1 Cytochrome C and Quinol oxidase polypeptide I; Cbb3-type cytochrome oxidase, subunit 1 YP_004278803.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase YP_004278804.1 Protein of unknown function DUF599; Predicted membrane protein YP_004278805.1 Protein of unknown function DUF1624; Predicted membrane protein YP_004278806.1 DNA binding; Predicted transcriptional regulators YP_004278807.1 Divalent cation transporter; Mg/Co/Ni transporter MgtE (contains CBS domain) YP_004278808.1 Oxidoreductase alpha (molybdopterin) subunit; Anaerobic dehydrogenases, typically selenocysteine-containing YP_004278810.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); N-formylmethionyl-tRNA deformylase YP_004278811.1 OsmC-like protein; Predicted redox protein, regulator of disulfide bond formation YP_004278813.1 PAS fold-3 YP_004278816.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; Lipoate-protein ligase B YP_004278817.1 Alcohol dehydrogenase superfamily, zinc-containing; Zn-dependent alcohol dehydrogenases YP_004278818.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004278820.1 Terpenoid synthase; Phytoene/squalene synthetase YP_004278821.1 Protein of unknown function (DUF498/DUF598); Uncharacterized conserved protein YP_004278822.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; Preprotein translocase subunit SecD YP_004278823.1 preprotein translocase, YajC subunit; Preprotein translocase subunit YajC YP_004278824.1 Protein of unknown function DUF815; Predicted ATPase (AAA+ superfamily) YP_004278825.1 Formaldehyde dehydrogenase, glutathione-independent, Alcohol dehydrogenase GroES-like domain; Threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004278826.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004278829.1 Serine acetyltransferase, N-terminal YP_004278830.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004278831.1 Uncharacterized protein conserved in bacteria YP_004278832.1 FAD dependent oxidoreductase; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_004278833.1 catalyzes the formation of L-homocysteine from cystathionine; Cystathionine beta-lyases/cystathionine gamma- synthases YP_004278834.1 Lysine-arginine-ornithine-binding periplasmic protein; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004278835.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004278836.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004278837.1 ABC transporter related; ABC-type polar amino acid transport system, ATPase component YP_004278839.1 Bacterial RecJ exonuclease; Single-stranded DNA-specific exonuclease YP_004278841.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_004278842.1 Pyridoxal phosphate-dependent transferase, major region, Aminotransferase class I and II; Aspartate/tyrosine/aromatic aminotransferase YP_004278844.1 Inosine-uridine nucleoside N-ribohydrolase YP_004278845.1 Protein of unknown function DUF81; Predicted permeases YP_004278847.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; Lauroyl/myristoyl acyltransferase YP_004278848.1 Alcohol dehydrogenase superfamily, zinc-containing, Zinc-binding dehydrogenase; NADPH:quinone reductase and related Zn- dependent oxidoreductases YP_004278849.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase YP_004278850.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase YP_004278852.1 Beta-hydroxyacyl-ACP dehydratase, FabA/FabZ; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases YP_004278853.1 Acyl carrier protein-like YP_004278854.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases YP_004278855.1 Bacterial regulatory proteins, crp family; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_004278858.1 Poly(R)-hydroxyalkanoic acid synthase, class I; Poly(3-hydroxyalkanoate) synthetase YP_004278859.1 Regulatory factor involved in maltose metabolism; DNA-binding protein, stimulates sugar fermentation YP_004278860.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_004278861.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair proteins YP_004278862.1 TadE-like protein; Flp pilus assembly protein TadG YP_004278863.1 Predicted membrane protein YP_004278864.1 Class-II DAHP synthetase family; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase YP_004278865.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes YP_004278866.1 Uncharacterized protein conserved in bacteria YP_004278867.1 Catalyzes D-ribose 5-phosphate -> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; Ribose 5-phosphate isomerase YP_004278868.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; Predicted phosphatases YP_004278869.1 Peptidoglycan binding-like; Uncharacterized protein conserved in bacteria YP_004278870.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; Fumarase YP_004278871.1 Esterase/lipase YP_004278872.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthase (UTP-ammonia lyase) YP_004278873.1 Preprotein translocase SecG subunit; Preprotein translocase subunit SecG YP_004278876.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit YP_004278877.1 ATP-dependent Clp protease, proteolytic subunit ClpP; Protease subunit of ATP-dependent Clp proteases YP_004278879.1 Bacterial regulatory protein, ArsR; Predicted transcriptional regulators YP_004278880.1 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthases and related enzymes YP_004278881.1 Response regulator receiver domain; Response regulator containing a CheY-like receiver domain and a GGDEF domain YP_004278882.1 FAD dependent oxidoreductase; glycine cleavage system T protein (aminomethyltransferase) YP_004278884.1 MscS Mechanosensitive ion channel; Small-conductance mechanosensitive channel YP_004278885.1 Transglycosylase-associated protein YP_004278886.1 Uncharacterised conserved protein UCP034077 YP_004278893.1 Bacterial Transmembrane Pair family; Predicted membrane protein YP_004278894.1 Predicted dienelactone hydrolase YP_004278895.1 Protein of unknown function DUF330; ABC-type uncharacterized transport system, auxiliary component YP_004278896.1 Mammalian cell entry related; ABC-type transport system involved in resistance to organic solvents, periplasmic component YP_004278897.1 ABC transporter related; ABC-type transport system involved in resistance to organic solvents, ATPase component YP_004278898.1 Protein of unknown function DUF140; ABC-type transport system involved in resistance to organic solvents, permease component YP_004278899.1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004278900.1 Metallophosphoesterase; Uncharacterized protein conserved in bacteria YP_004278901.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate; Malic enzyme YP_004278903.1 Cob(II)yrinic acid a,c-diamide reductase YP_004278904.1 Six-bladed beta-propeller, TolB-like; Periplasmic component of the Tol biopolymer transport system YP_004278905.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Lactoylglutathione lyase and related lyases YP_004278906.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthase YP_004278907.1 cyclic glucan phosphoglycerol modification protein; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily YP_004278908.1 Protein of unknown function DUF1003; Predicted membrane protein YP_004278910.1 catalyzes the conversion of NADPH to NADH; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes YP_004278913.1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Predicted amidohydrolase YP_004278914.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) YP_004278915.1 Protein of unknown function DUF1127 YP_004278916.1 Protein of unknown function DUF1127 YP_004278917.1 TrmFO; Gid; glucose-inhibited division protein; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; NAD(FAD)-utilizing enzyme possibly involved in translation YP_004278918.1 TadE-like YP_004278919.1 TadE-like; Flp pilus assembly protein TadG YP_004278921.1 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; Zn-dependent alcohol dehydrogenases, class III YP_004278923.1 Acyl carrier protein-like YP_004278924.1 AMP-dependent synthetase and ligase; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_004278925.1 Orn/DAP/Arg decarboxylase 2 YP_004278926.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; Anthranilate/para-aminobenzoate synthases component I YP_004278927.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); Queuine/archaeosine tRNA-ribosyltransferase YP_004278928.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) YP_004278929.1 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family YP_004278930.1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family YP_004278931.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_004278935.1 Parvulin-like peptidyl-prolyl isomerase YP_004278936.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_004278937.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_004278938.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; Molybdenum cofactor biosynthesis enzyme YP_004278939.1 Molybdopterin binding, MoeA N-terminal region (domain I and II); Molybdopterin biosynthesis enzyme YP_004278940.1 diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004278941.1 FMN-binding split barrel, related, Pyridoxamine 5'-phosphate oxidase; Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase YP_004278942.1 Sodium/hydrogen exchanger family; Kef-type K+ transport systems, membrane components YP_004278943.1 Protein of unknown function DUF971; Uncharacterized protein conserved in bacteria YP_004278944.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; Molybdenum cofactor biosynthesis enzyme YP_004278945.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004278946.1 Drug resistance transporter Bcr/CflA subfamily; Permeases of the major facilitator superfamily YP_004278947.1 Links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_004278948.1 Molybdopterin-guanine dinucleotide biosynthesis MobB region; Molybdopterin-guanine dinucleotide biosynthesis protein YP_004278949.1 Peptidase family M23; Membrane proteins related to metalloendopeptidases YP_004278950.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; Protein-L-isoaspartatecarboxylmethyltransferase YP_004278951.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; Predicted acid phosphatase YP_004278952.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_004278953.1 Sec-independent periplasmic protein translocase; Sec-independent protein secretion pathway component TatC YP_004278954.1 mediates the export of protein precursors bearing twin-arginine signal peptides; Sec-independent protein secretion pathway components YP_004278955.1 TatA; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; Sec-independent protein secretion pathway components YP_004278956.1 Prokaryotic chromosome segregation and condensation protein ScpB; Chromosome segregation and condensation protein B YP_004278957.1 Prokaryotic chromosome segregation and condensation protein ScpA; Rec8/ScpA/Scc1-like protein (kleisin family) YP_004278958.1 glycoside hydrolase, family 3, N-terminal; Beta-glucosidase-related glycosidases YP_004278959.1 Sporulation/cell division region, bacteria YP_004278960.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_004278961.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; dGTP triphosphohydrolase YP_004278962.1 Iron-sulphur cluster biosynthesis; Uncharacterized conserved protein YP_004278963.1 Exodeoxyribonuclease III xth, Endonuclease/Exonuclease/phosphatase family; Exonuclease III YP_004278964.1 Tetratricopeptide-like helical; FOG: TPR repeat, SEL1 subfamily YP_004278966.1 Membrane protein involved in aromatic hydrocarbon degradation YP_004278967.1 valine-tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; Isoleucyl-tRNA synthetase YP_004278968.1 Uncharacterized protein conserved in bacteria YP_004278969.1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase; Protein-L-isoaspartatecarboxylmethyltransferase YP_004278973.1 Protein of unknown function DUF982 YP_004278975.1 stationary phase that binds TrpR repressor; Multimeric flavodoxin WrbA YP_004278976.1 molybdopterin binding domain; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA YP_004278977.1 Universal stress protein family; Universal stress protein UspA and related nucleotide-binding proteins YP_004278978.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins YP_004278979.1 Catalyzes the rate-limiting step in dNTP synthesis; Ribonucleotide reductase, subunit alpha YP_004278982.1 Natural resistance-associated macrophage protein; Mn2+ and Fe2+ transporters of the NRAMP family YP_004278984.1 ABC-type multidrug transport system, ATPase and permease components YP_004278985.1 Domain of unknown function DUF20; Predicted permease YP_004278986.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases YP_004278988.1 Uncharacterised conserved protein UCP035865; Uncharacterized protein conserved in bacteria YP_004278989.1 FMN-binding split barrel, related; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004278990.1 Nitroreductase YP_004278992.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_004278993.1 Protein of unknown function DUF1697; Uncharacterized protein conserved in bacteria YP_004278994.1 Protein of unknown function DUF37; Uncharacterized conserved protein YP_004278995.1 NIF system FeS cluster assembly, NifU, N-terminal; NifU homolog involved in Fe-S cluster formation YP_004278996.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_004278997.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_004278998.1 Patatin-like phospholipase; Predicted esterase of the alpha-beta hydrolase superfamily YP_004278999.1 Cystathionine beta-synthase, core; FOG: CBS domain YP_004279000.1 Peptidase S54, Rhomboid family; Uncharacterized membrane protein (homolog of Drosophila rhomboid) YP_004279001.1 Protein of unknown function DUF1457; Uncharacterized protein conserved in bacteria YP_004279004.1 Predicted transglutaminase-like cysteine peptidase, BTLCP, Bacterial protein of unknown function (DUF920); Predicted periplasmic protein YP_004279005.1 Protein of unknown function (DUF1489); Uncharacterized conserved protein YP_004279006.1 Iron-sulphur-dependent L-serine dehydratase single chain form, Serine dehydratase alpha chain; L-serine deaminase YP_004279009.1 Predicted periplasmic protein YP_004279010.1 Entericidin EcnAB YP_004279011.1 Formyl transferase, N-terminal; methionyl-tRNA formyltransferase YP_004279012.1 5,10-methylenetetrahydrofolate reductase YP_004279013.1 LysR substrate binding domain; Transcriptional regulator YP_004279015.1 ThiJ/PfpI; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_004279016.1 Carbohydrate kinase; Predicted sugar kinase YP_004279018.1 Nitrogen regulatory PII-like, alpha/beta YP_004279019.1 Glutamine synthetase type I, catalytic domain YP_004279020.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004279021.1 Hemimethylated DNA-binding region; Uncharacterized conserved protein YP_004279022.1 Invasion associated locus B (IalB) protein; Invasion protein B, involved in pathogenesis YP_004279023.1 Bacterial extracellular solute-binding protein, family 5; ABC-type oligopeptide transport system, periplasmic component YP_004279024.1 Thioredoxin-like fold; Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis YP_004279025.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004279028.1 Transcription-repair coupling factor, CarD-like/TRCF domain; Transcription-repair coupling factor (superfamily II helicase) YP_004279029.1 Protein of unknown function DUF339; Uncharacterized conserved protein YP_004279030.1 catalyzes branch migration in Holliday junction intermediates; RecG-like helicase YP_004279031.1 5'(3')-deoxyribonucleotidase YP_004279032.1 Prevent-host-death protein YP_004279033.1 PilT protein, N-terminal; Uncharacterized protein conserved in bacteria YP_004279034.1 Protein of unknown function DUF502; Uncharacterized conserved protein YP_004279035.1 GCN5-related N-acetyltransferase; Predicted acetyltransferase YP_004279036.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains YP_004279037.1 UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I- patch acetyltransferase domains) YP_004279038.1 GntR, C-terminal; Transcriptional regulators YP_004279039.1 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein YP_004279040.1 Branched-chain amino acid transport system / permease component; Uncharacterized ABC-type transport system, permease component YP_004279041.1 Branched-chain amino acid transport system / permease component; ABC-type uncharacterized transport system, permease component YP_004279042.1 ABC transporter related; ABC-type uncharacterized transport systems, ATPase components YP_004279043.1 CDP-alcohol phosphatidyltransferase; Phosphatidylserine synthase YP_004279044.1 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, FAD binding domain; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_004279045.1 Membrane transport protein; Predicted permeases YP_004279046.1 Cytochrome c biogenesis protein, transmembrane region; Cytochrome c biogenesis protein YP_004279047.1 Protein of unknown function DUF1003; Predicted membrane protein YP_004279048.1 FMN-binding split barrel, related; Predicted flavin-nucleotide-binding protein YP_004279049.1 glycosyl transferase, family 25; glycosyltransferase involved in LPS biosynthesis YP_004279050.1 Hedgehog/DD-peptidase, zinc-binding motif, Peptidase M15; Uncharacterized protein conserved in bacteria YP_004279051.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004279052.1 Cold-shock protein, DNA-binding; Cold shock proteins YP_004279053.1 Protein of unknown function DUF192; Uncharacterized conserved protein YP_004279054.1 Transport-associated YP_004279055.1 Protein of unknown function DUF982 YP_004279056.1 glycosyltransferases, probably involved in cell wall biogenesis YP_004279064.1 Hedgehog/DD-peptidase, zinc-binding motif, D-alanyl-D-alanine carboxypeptidase; Phage-related minor tail protein YP_004279065.1 Phage Terminase; Phage terminase-like protein, large subunit YP_004279066.1 Phage terminase, small subunit, , P27; Phage terminase, small subunit YP_004279067.1 Protein of unknown function DUF1026; Bacteriophage head-tail adaptor YP_004279069.1 Phage protein, HK97, gp10 YP_004279074.1 phage major capsid protein, HK97 family; Predicted phage phi-C31 gp36 major capsid-like protein YP_004279076.1 Phage portal protein; Phage-related protein YP_004279077.1 DNA breaking-rejoining enzyme, catalytic core; Integrase YP_004279079.1 Uncharacterized protein conserved in bacteria YP_004279081.1 efflux transporter, RND family, MFP subunit; Membrane-fusion protein YP_004279082.1 ABC transporter related; ABC-type antimicrobial peptide transport system, ATPase component YP_004279083.1 Protein of unknown function DUF214, permase ; ABC-type antimicrobial peptide transport system, permease component YP_004279085.1 Iron-sulphur cluster biosynthesis; Uncharacterized conserved protein YP_004279086.1 SUF system FeS cluster assembly associated, Domain of unknown function DUF59; Predicted metal-sulfur cluster biosynthetic enzyme YP_004279087.1 Pyridoxal phosphate-dependent transferase, major region; Selenocysteine lyase/Cysteine desulfurase YP_004279088.1 SUF system FeS cluster assembly, SufD; ABC-type transport system involved in Fe-S cluster assembly, permease component YP_004279089.1 SUF system FeS cluster assembly, SufC ATPase; ABC-type oligopeptide transport system, ATPase component YP_004279090.1 with SufCD activates cysteine desulfurase SufS; ABC-type transport system involved in Fe-S cluster assembly, permease component YP_004279091.1 Pyridoxal phosphate-dependent transferase, major region; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes YP_004279092.1 Predicted hydrolase of the alpha/beta superfamily YP_004279093.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases YP_004279095.1 Predicted membrane protein YP_004279096.1 Thioredoxin-like fold; Peroxiredoxin YP_004279097.1 Protein of unknown function (DUF455); Uncharacterized protein conserved in bacteria YP_004279098.1 Peptidase family M23; Membrane proteins related to metalloendopeptidases YP_004279099.1 DEAD-like helicase, N-terminal; Superfamily II DNA and RNA helicases YP_004279100.1 NUDIX domain; ADP-ribose pyrophosphatase YP_004279102.1 Extracellular ligand-binding receptor; ABC-type branched-chain amino acid transport systems, periplasmic component YP_004279103.1 Pentose-5-phosphate-3-epimerase YP_004279105.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_004279106.1 Alpha/Beta hydrolase family of unknown function (DUF1234); Predicted esterase of the alpha/beta hydrolase fold YP_004279107.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase YP_004279108.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component YP_004279109.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain YP_004279111.1 Uncharacterized conserved small protein YP_004279112.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators containing a DNA- binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs YP_004279113.1 Lipid A 3-O-deacylase (PagL) YP_004279114.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain YP_004279115.1 BolA-like protein; Stress-induced morphogen (activity unknown) YP_004279118.1 Monothiol glutaredoxin YP_004279119.1 Drug resistance transporter Bcr/CflA subfamily; Permeases of the major facilitator superfamily YP_004279120.1 Inositol monophosphatase family; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004279121.1 Inositol monophosphatase family; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004279122.1 PP-loop ATPase, YdaO-related; tRNA(Ile)-lysidine synthase MesJ YP_004279123.1 catalyzes the formation of glutamate from glutamine; Glutaminase YP_004279124.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions; Ribosomal protein S4 and related proteins YP_004279125.1 Integral membrane protein TerC family; Membrane protein TerC, possibly involved in tellurium resistance YP_004279127.1 Predicted ATPase, Atu1862 type; Predicted ATPase YP_004279128.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004279129.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004279133.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_004279134.1 RNA methyltransferase TrmH, group 1; rRNA methylase YP_004279136.1 Converts isocitrate to alpha ketoglutarate; Isocitrate dehydrogenases YP_004279137.1 Glutathione S-transferase, C-terminal-like & N-terminal domain YP_004279138.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Lactoylglutathione lyase and related lyases YP_004279139.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_004279140.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; RecA/RadA recombinase YP_004279141.1 Carbohydrate/purine kinase; Sugar kinases, ribokinase family YP_004279142.1 Indigoidine synthase A like protein; Uncharacterized enzyme involved in pigment biosynthesis YP_004279143.1 Outer membrane protein, OmpA/MotB, C-terminal; Outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_004279145.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004279146.1 Binding-protein-dependent transport systems inner membrane component; ABC-type arginine transport system, permease component YP_004279147.1 Binding-protein-dependent transport systems inner membrane component; ABC-type arginine/histidine transport system, permease component YP_004279148.1 Usg-like family; Usg protein, subunit of phosphoribosylanthranilate isomerase YP_004279149.1 methyltransferase domain; Predicted methyltransferase (contains TPR repeat) YP_004279150.1 ABC transporter, substrate-binding protein, aliphatic sulphonates; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004279151.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004279153.1 Micrococcal nuclease (thermonuclease) homologs YP_004279154.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004279155.1 Prokaryotic diacylglycerol kinase YP_004279156.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; NaMN:DMB phosphoribosyltransferase YP_004279157.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; Cobalamin-5-phosphate synthase YP_004279158.1 Protein of unknown function DUF1289 YP_004279159.1 Conserved hypothetical protein CHP02281; Predicted aspartyl protease YP_004279160.1 ABC-2 type transporter; ABC-type multidrug transport system, permease component YP_004279161.1 ABC transporter; ABC-type multidrug transport system, ATPase component YP_004279162.1 Protein of unknown function DUF81; Predicted permeases YP_004279163.1 Extensin-like protein C-terminus; Uncharacterized protein conserved in bacteria YP_004279164.1 methyl-accepting chemotaxis protein (MCP) signaling domain YP_004279166.1 ATPase family associated with various cellular activities (AAA); ATPase related to the helicase subunit of the Holliday junction resolvase YP_004279167.1 Peptidase S1C, Do, Trypsin; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain YP_004279168.1 Uncharacterized protein conserved in bacteria, lipoprotein YP_004279169.1 Beta-lactamase class C and other penicillin binding proteins YP_004279170.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Dihydroxyacid dehydratase/phosphogluconate dehydratase YP_004279171.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; Sulfite oxidase and related enzymes YP_004279172.1 Ferric reductase-like transmembrane component, N-terminal; Predicted membrane protein YP_004279174.1 Protein of unknown function DUF817; Uncharacterized integral membrane protein YP_004279175.1 is a component of the macrolide binding site in the peptidyl transferase center; Ribosomal protein L17 YP_004279176.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the subunit alpha is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase, subunit alpha/40 kD subunit YP_004279177.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; Ribosomal protein S11 YP_004279178.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; Ribosomal protein S13 YP_004279179.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; Adenylate kinase and related kinases YP_004279180.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_004279181.1 late assembly protein; Ribosomal protein L15 YP_004279182.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; Ribosomal protein L30/L7E YP_004279183.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; Ribosomal protein S5 YP_004279184.1 binds 5S rRNA along with protein L5 and L25; Ribosomal protein L18 YP_004279185.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; Ribosomal protein L6P/L9E YP_004279186.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Ribosomal protein S8 YP_004279187.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; Ribosomal protein S14 YP_004279188.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; Ribosomal protein L5 YP_004279189.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; Ribosomal protein L24 YP_004279190.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; Ribosomal protein L14 YP_004279191.1 primary binding protein; helps mediate assembly; involved in translation fidelity; Ribosomal protein S17 YP_004279192.1 one of the stabilizing components for the large ribosomal subunit; Ribosomal protein L29 YP_004279193.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; Ribosomal protein L16/L10E YP_004279194.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; Ribosomal protein S3 YP_004279195.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; Ribosomal protein L22 YP_004279196.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; Ribosomal protein S19 YP_004279197.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; Ribosomal protein L2 YP_004279198.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; Ribosomal protein L23 YP_004279199.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; Ribosomal protein L4 YP_004279200.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; Ribosomal protein L3 YP_004279201.1 Ribosomal protein S10 YP_004279202.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; GTPases - translation elongation factors YP_004279203.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; Translation elongation factors (GTPases) YP_004279204.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; Ribosomal protein S7 YP_004279205.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; Ribosomal protein S12 YP_004279208.1 Winged helix repressor DNA-binding; DNA-binding HTH domain-containing proteins YP_004279209.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase, beta' subunit/160 kD subunit YP_004279210.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase, beta subunit/140 kD subunit YP_004279211.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; Ribosomal protein L7/L12 YP_004279212.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; Ribosomal protein L10 YP_004279213.1 in Escherichia coli and methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; Ribosomal protein L1 YP_004279214.1 binds directly to 23S ribosomal RNA; Ribosomal protein L11 YP_004279215.1 Modulates Rho-dependent transcription termination; Transcription antiterminator YP_004279216.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; Preprotein translocase subunit SecE YP_004279217.1 glycosyl transferase, family 2; Predicted glycosyltransferases YP_004279218.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; GTPases - translation elongation factors YP_004279219.1 Membrane protein TerC, possibly involved in tellurium resistance YP_004279222.1 BA14K-like YP_004279224.1 RNA methyltransferase TrmH, group 3, SpoU rRNA methylase family; rRNA methylases YP_004279225.1 Thioesterase superfamily YP_004279229.1 Peptidase M4, propeptide, PepSY; Uncharacterized iron-regulated membrane protein YP_004279230.1 Protein of unknown function DUF1486; Uncharacterized protein conserved in bacteria YP_004279231.1 NADH-flavin reductase YP_004279232.1 Helix-turn-helix, HxlR type; Predicted transcriptional regulators YP_004279233.1 Protein of unknown function DUF486; Uncharacterized protein conserved in bacteria YP_004279234.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; Helicase subunit of the DNA excision repair complex YP_004279235.1 esterase; Predicted esterase YP_004279236.1 Protein of unknown function DUF1801; Uncharacterized conserved protein YP_004279237.1 PRC-barrel domain; Uncharacterized protein conserved in bacteria YP_004279238.1 Protein of unknown function DUF922, bacterial; Predicted secreted Zn-dependent protease YP_004279239.1 Heat shock protein DnaJ, N-terminal; DnaJ-class molecular chaperone YP_004279241.1 diguanylate cyclase (GGDEF) domain; c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) YP_004279242.1 Endonuclease/Exonuclease/phosphatase family; Predicted extracellular nuclease YP_004279243.1 ABC transporter related; ABC-type sugar transport systems, ATPase components YP_004279244.1 Binding-protein-dependent transport systems inner membrane component; ABC-type Fe3+ transport system, permease component YP_004279245.1 Bacterial extracellular solute-binding protein, family 1; ABC-type Fe3+ transport system, periplasmic component YP_004279246.1 Aminotransferase class I and II; Transcriptional regulators containing a DNA- binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs YP_004279247.1 RbsD / FucU transport protein family; Fucose dissimilation pathway protein FucU YP_004279249.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_004279250.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; Transcriptional regulator YP_004279251.1 AraC-type transcriptional regulator, N-terminal; AraC-type DNA-binding domain-containing proteins YP_004279252.1 Alcohol dehydrogenase superfamily, zinc-containing; Zn-dependent alcohol dehydrogenases YP_004279253.1 NADH dehydrogenase, FAD-containing subunit YP_004279254.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); Pyridoxal phosphate biosynthesis protein YP_004279255.1 DNA binding; Predicted transcriptional regulators YP_004279256.1 ATP-dependent exoDNAse (exonuclease V), subunit alpha - helicase superfamily I member YP_004279257.1 Predicted nucleoside-diphosphate-sugar epimerases YP_004279258.1 Predicted integral membrane protein YP_004279259.1 Activator of Hsp90 ATPase homolog 1-like protein; Uncharacterized conserved protein YP_004279260.1 Bacterial regulatory protein, ArsR; Predicted transcriptional regulators YP_004279261.1 Uncharacterised conserved lipoprotein; Uncharacterized protein conserved in bacteria YP_004279262.1 RNA polymerase sigma factor, sigma-70 family; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004279263.1 Predicted transmembrane transcriptional regulator (anti-sigma factor) YP_004279264.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004279265.1 Aldo/keto reductase family; Aldo/keto reductases, related to diketogulonate reductase YP_004279266.1 Activator of Hsp90 ATPase homologue 1-like; Uncharacterized conserved protein YP_004279267.1 transcriptional regulator, ArsR family; Predicted transcriptional regulators YP_004279268.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Acetolactate synthase, small (regulatory) subunit YP_004279269.1 Acetolactate synthase, large subunit, biosynthetic; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] YP_004279270.1 Protein of unknown function DUF87; Predicted ATPase YP_004279271.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_004279273.1 GCN5-related N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004279274.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004279275.1 Peptidase S1C, Do; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain YP_004279276.1 SPFH domain / Band 7 family; Membrane protease subunits, stomatin/prohibitin homologs YP_004279277.1 SPFH domain / Band 7 family; Membrane protease subunits, stomatin/prohibitin homologs YP_004279279.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_004279281.1 Protein of unknown function DUF1321; Uncharacterized protein conserved in bacteria YP_004279283.1 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis YP_004279285.1 Uncharacterized protein involved in outer membrane biogenesis YP_004279286.1 FAD dependent oxidoreductase; FAD/FMN-containing dehydrogenases YP_004279287.1 Acriflavin resistance protein, AcrB/AcrD/AcrF family; Cation/multidrug efflux pump YP_004279288.1 efflux transporter, RND family, MFP subunit; Membrane-fusion protein YP_004279289.1 Carboxymuconolactone decarboxylase family, alkylhydroperoxidase AhpD family core domain; Uncharacterized conserved protein YP_004279290.1 DNA helicase, UvrD/REP type, ATP-dependent DNA helicase PcrA; Superfamily I DNA and RNA helicases YP_004279291.1 glycosyltransferase family 25 (LPS biosynthesis protein); glycosyltransferase involved in LPS biosynthesis YP_004279293.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004279294.1 ABC transporter substrate-binding protein (glycine betaine); ABC-type proline/glycine betaine transport systems, periplasmic components YP_004279295.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004279296.1 Protein of unknown function DUF606; Uncharacterized protein conserved in bacteria YP_004279297.1 Protein of unknown function DUF606; Uncharacterized protein conserved in bacteria YP_004279299.1 Isochorismatase family; Amidases related to nicotinamidase YP_004279300.1 Uncharacterized conserved protein YP_004279301.1 AzlC protein; Predicted branched-chain amino acid permease (azaleucine resistance) YP_004279302.1 Branched-chain amino acid transport protein (AzlD); Predicted membrane protein YP_004279303.1 metallopeptidase family M24; Xaa-Pro aminopeptidase YP_004279305.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; Ribosomal protein L11 methylase YP_004279306.1 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems YP_004279308.1 CheW-like domain; Chemotaxis signal transduction protein YP_004279309.1 CreA protein; Uncharacterized protein conserved in bacteria YP_004279310.1 Exonuclease; DNA polymerase III, subunit alpha (gram- positive type) YP_004279311.1 LysR, substrate-binding; Transcriptional regulator YP_004279312.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004279313.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004279314.1 Phosphotransferase enzyme family; Predicted aminoglycoside phosphotransferase YP_004279315.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; NAD-dependent DNA ligase (contains BRCT domain type II) YP_004279317.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004279318.1 ATPase involved in DNA repair YP_004279319.1 DNA uptake lipoprotein YP_004279320.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-acyl-N-acetylglucosamine deacetylase YP_004279321.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; Cell division GTPase YP_004279322.1 Cell division protein FtsA; Actin-like ATPase involved in cell division YP_004279323.1 Cell division septal protein YP_004279324.1 D-alanine-D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine-D-alanine ligase and related ATP- grasp enzymes YP_004279325.1 Major facilitator superfamily YP_004279326.1 diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004279327.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylmuramate dehydrogenase YP_004279328.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_004279329.1 UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase YP_004279330.1 Bacterial cell division membrane protein YP_004279331.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_004279332.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase YP_004279333.1 UDP-MurNAc-pentapeptide synthetase; UDP-N-acetylmuramyl pentapeptide synthase YP_004279334.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramyl tripeptide synthase YP_004279335.1 penicillin binding protein transpeptidase domain; Cell division protein FtsI/penicillin-binding protein 2 YP_004279336.1 Predicted secreted (periplasmic) protein YP_004279337.1 Bacterial methyltransferase, MraW methylase family; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis YP_004279338.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; Uncharacterized protein conserved in bacteria YP_004279339.1 FAD dependent oxidoreductase; glycine/D-amino acid oxidases (deaminating) YP_004279340.1 FAD dependent oxidoreductase; glycine/D-amino acid oxidases (deaminating) YP_004279341.1 Lytic transglycosylase-like, catalytic; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) YP_004279342.1 N-acetylmuramoyl-L-alanine amidase, family 2; N-acetyl-anhydromuramyl-L-alanine amidase YP_004279343.1 Protein of unknown function DUF1332; DnaJ-domain-containing proteins 1 YP_004279344.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate; 6-phosphofructokinase YP_004279345.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004279346.1 Lytic transglycosylase-like, catalytic; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) YP_004279347.1 S-adenosylmethionine:diacylglycerol 3-amino-3- carboxypropyl transferase YP_004279348.1 methyltransferase type 11; SAM-dependent methyltransferases YP_004279349.1 glycosyl hydrolases family 25; Lyzozyme M1 (1,4-beta-N-acetylmuramidase) YP_004279350.1 Membrane-bound lytic murein transglycosylase B YP_004279352.1 methyltransferase type 11; methylase involved in ubiquinone/menaquinone biosynthesis YP_004279353.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ATPase components of ABC transporters with duplicated ATPase domains YP_004279354.1 Alpha/beta hydrolase fold-1; Lysophospholipase YP_004279355.1 CoA-transferase family III; Predicted acyl-CoA transferases/carnitine dehydratase YP_004279356.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] YP_004279357.1 Heme iron utilization protein, pyridoxamine 5'-phosphate region; heme iron utilization protein YP_004279358.1 translation initiation inhibitor, yjgF family YP_004279359.1 Protein of unknown function DUF442; Uncharacterized protein conserved in bacteria YP_004279361.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004279363.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279364.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; Transcriptional regulator YP_004279365.1 Cobyrinic acid a,c-diamide synthase; ATPases involved in chromosome partitioning YP_004279367.1 Iron-containing alcohol dehydrogenase; Alcohol dehydrogenase, class IV YP_004279368.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004279369.1 Glutamine synthetase/guanido kinase, catalytic region YP_004279370.1 Amino acid/polyamine transporter I; Amino acid transporters YP_004279371.1 Uncharacterized conserved protein UCP029730; Predicted N-formylglutamate amidohydrolase YP_004279372.1 Sugar isomerase (SIS); Transcriptional regulators YP_004279373.1 Bacterial extracellular solute-binding protein, family 1; ABC-type Fe3+ transport system, periplasmic component YP_004279374.1 Binding-protein-dependent transport systems inner membrane component; ABC-type uncharacterized transport system, permease component YP_004279375.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component II YP_004279376.1 ABC transporter related; ABC-type spermidine/putrescine transport systems, ATPase components YP_004279377.1 Alcohol dehydrogenase superfamily, zinc-containing; Zn-dependent alcohol dehydrogenases YP_004279379.1 AAA+ ATPase, core; Predicted ATPase YP_004279380.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279381.1 one of two methionine synthases in Escherichia coli; meth catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; methionine synthase I, cobalamin-binding domain YP_004279382.1 Six-hairpin glycosidase-like, N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acyl-D-glucosamine 2-epimerase YP_004279383.1 Protein-tyrosine phosphatase, Tyr-specific/dual-specificity type; Protein tyrosine/serine phosphatase YP_004279385.1 Porin, alpha proteobacteria type; Opacity protein and related surface antigens YP_004279387.1 Protein of unknown function DUF541; Uncharacterized conserved protein YP_004279389.1 Protein of unknown function UPF0047; Uncharacterized conserved protein YP_004279390.1 Bacteriophytochrome, CheY-like; Bacteriophytochrome (light-regulated signal transduction histidine kinase) YP_004279391.1 Protein of unknown function DUF930 YP_004279392.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) YP_004279393.1 synthesizes RNA primers at the replication forks; DNA primase (bacterial type) YP_004279394.1 Yqey-like protein; Uncharacterized conserved protein YP_004279395.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Carbamoylphosphate synthase small subunit YP_004279396.1 Multi antimicrobial extrusion protein MatE; Na+-driven multidrug efflux pump YP_004279397.1 Bacterial chemotaxis sensory transducer, methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis protein YP_004279399.1 neutral zinc metallopeptidase; Predicted metalloprotease YP_004279400.1 Predicted membrane protein YP_004279401.1 LytTR transmembrane transcriptional regulator, ; Response regulator of the LytR/AlgR family YP_004279402.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Carbamoylphosphate synthase large subunit (split gene in MJ) YP_004279403.1 diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004279404.1 Phage SPO1 DNA polymerase-related protein, Uracil DNA glycosylase superfamily; Uracil-DNA glycosylase YP_004279405.1 Elongator protein 3/MiaB/NifB; Predicted DNA-binding protein with the Helix- hairpin-helix motif YP_004279406.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; Transcription elongation factor YP_004279407.1 glycosyl transferases group 1; glycosyltransferase YP_004279408.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004279410.1 LysR substrate binding domain; Transcriptional regulator YP_004279411.1 Bacterial regulatory protein, ArsR; Predicted transcriptional regulators YP_004279412.1 NADH:flavin oxidoreductase / NADH oxidase family; NADH:flavin oxidoreductases, Old Yellow Enzyme family YP_004279414.1 Nucleoside-diphosphate-sugar epimerases YP_004279415.1 LysR substrate binding domain; Transcriptional regulator YP_004279418.1 Sodium/calcium exchanger membrane region YP_004279419.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Aspartate/tyrosine/aromatic aminotransferase YP_004279420.1 EAL; FOG: EAL domain YP_004279422.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004279424.1 Cold shock, CspA; Cold shock proteins YP_004279425.1 Metallo-beta-lactamase superfamily; Zn-dependent hydrolases, including glyoxylases YP_004279426.1 Protein of unknown function DUF1236; Uncharacterized protein with a bacterial SH3 domain homologue YP_004279427.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004279428.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004279429.1 two component sensor kinase; Signal transduction histidine kinase YP_004279430.1 export-related chaperone CsaA; EMAP domain YP_004279431.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_004279432.1 Protein of unknown function DUF1790; Uncharacterized conserved protein YP_004279433.1 Protein of unknown function DUF526; Uncharacterized protein conserved in bacteria YP_004279435.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; Prolipoprotein diacylglyceryltransferase YP_004279436.1 Protein of unknown function DUF185; Uncharacterized conserved protein YP_004279437.1 Uncharacterised ACR, YfiH family COG1496; Uncharacterized conserved protein YP_004279438.1 Peptidase M24, catalytic core; Xaa-Pro aminopeptidase YP_004279440.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; Phosphoribosylpyrophosphate synthetase YP_004279441.1 Phosphatidic acid phosphatase type 2-like; Membrane-associated phospholipid phosphatase YP_004279442.1 glycosyl transferase, family 39; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family YP_004279443.1 Uncharacterised conserved protein, lipid A biosynthesis N-terminal region; Predicted membrane protein YP_004279444.1 glycosyl transferase, family 2; glycosyltransferases involved in cell wall biogenesis YP_004279445.1 methyl-accepting chemotaxis protein (MCP) signaling domain YP_004279446.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004279447.1 Bacterial regulatory protein, Fis family; Transcriptional activator of acetoin/glycerol metabolism YP_004279448.1 diguanylate cyclase (GGDEF) domain; c-di-GMP phosphodiesterase class I (EAL domain) YP_004279449.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; Ribosomal protein L25 (general stress protein Ctc) YP_004279450.1 diguanylate cyclase (GGDEF) domain; c-di-GMP phosphodiesterase class I (EAL domain) YP_004279451.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004279452.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_004279453.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family YP_004279454.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; Uncharacterized conserved protein YP_004279455.1 Conserved hypothetical protein CHP00092, Protein of unknown function (DUF933); Predicted GTPase, translation factor YP_004279456.1 MaoC-like dehydratase; Acyl dehydratase YP_004279457.1 MaoC-like dehydratase; Acyl dehydratase YP_004279458.1 methyltransferase type 12; SAM-dependent methyltransferases YP_004279459.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins YP_004279462.1 Cytochrome C1 family; Cytochrome c1 YP_004279463.1 Cytochrome b(N-terminal)/b6/petB; Cytochrome b subunit of the bc complex YP_004279464.1 ubiquinol-cytochrome c reductase, iron-sulfur subunit; Rieske Fe-S protein YP_004279465.1 Endonuclease/exonuclease/phosphatase; Uncharacterized protein conserved in bacteria YP_004279466.1 ABC transporter, transmembrane region, type 1; ABC-type multidrug transport system, ATPase and permease components YP_004279467.1 ABC transporter, transmembrane region, type 1; ABC-type multidrug transport system, ATPase and permease components YP_004279469.1 tRNA/rRNA methyltransferase, SpoU; Predicted rRNA methylase (SpoU class) YP_004279470.1 sodium-dependent inorganic phosphate (Pi) transporter; Na+/phosphate symporter YP_004279472.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_004279474.1 Predicted small metal-binding protein YP_004279475.1 CCA-adding enzyme, Poly A polymerase head domain; tRNA nucleotidyltransferase/poly(A) polymerase YP_004279477.1 Protein of unknown function DUF1285; Uncharacterized protein conserved in bacteria YP_004279478.1 ATPase associated with various cellular activities, AAA-3; MoxR-like ATPases YP_004279479.1 Protein of unknown function DUF58; Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) YP_004279480.1 Double-transmembrane region, N-terminal YP_004279482.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Histone acetyltransferase HPA2 and related acetyltransferases YP_004279483.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279484.1 GCN5-related N-acetyltransferase; Acetyltransferases YP_004279485.1 Glutathione S-transferase, C-terminal-like; Predicted glutathione S-transferase YP_004279486.1 NUDIX hydrolase, core; ADP-ribose pyrophosphatase YP_004279487.1 Calcineurin-like phosphoesterase; Predicted phosphohydrolases YP_004279488.1 Yeast 2-isopropylmalate synthase; Isopropylmalate/homocitrate/citramalatesynthases YP_004279489.1 Uncharacterized protein involved in benzoate metabolism YP_004279490.1 Protein of unknown function DUF1109; Uncharacterized protein conserved in bacteria YP_004279491.1 RNA polymerase sigma factor, sigma-70 family; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004279493.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; Protease subunit of ATP-dependent Clp proteases YP_004279494.1 HupE/UreJ protein; Hydrogenase/urease accessory protein YP_004279495.1 Uncharacterized protein conserved in bacteria YP_004279496.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; Enzyme related to GTP cyclohydrolase I YP_004279497.1 Cation efflux family; Predicted Co/Zn/Cd cation transporters YP_004279498.1 Lactoylglutathione lyase and related lyases YP_004279499.1 Extracellular ligand-binding receptor; ABC-type branched-chain amino acid transport systems, periplasmic component YP_004279501.1 Bacterial regulatory protein, arsR family; Predicted transcriptional regulators YP_004279502.1 glycine betaine/L-proline transport ATP binding subunit; ABC-type proline/glycine betaine transport system, ATPase component YP_004279503.1 Binding-protein-dependent transport systems inner membrane component; ABC-type proline/glycine betaine transport system, permease component YP_004279504.1 Substrate-binding region of ABC-type glycine betaine transport system; ABC-type proline/glycine betaine transport systems, periplasmic components YP_004279505.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_004279506.1 Copper binding proteins, plastocyanin/azurin family; Plastocyanin YP_004279507.1 Uncharacterized protein conserved in bacteria YP_004279508.1 Bacterial regulatory proteins, luxR family; DNA-binding HTH domain-containing proteins YP_004279509.1 Protein of unknown function UPF0114; Predicted membrane protein YP_004279510.1 TonB-dependent haem/haemoglobin receptor; Outer membrane receptor proteins, mostly Fe transport YP_004279511.1 Extensin-like protein C-terminus; Uncharacterized protein conserved in bacteria YP_004279512.1 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Anthranilate/para-aminobenzoate synthases component I YP_004279513.1 Metal-dependent phosphohydrolase, HD region; HD-GYP domain YP_004279514.1 Amidohydrolase family YP_004279515.1 GCN5-related N-acetyltransferase; Sortase and related acyltransferases YP_004279516.1 glycoside hydrolase, catalytic core; glycosidases YP_004279517.1 Carbohydrate/purine kinase; Sugar kinases, ribokinase family YP_004279518.1 glycosyl transferase, group 1 YP_004279519.1 Protein of unknown function (DUF2026) YP_004279520.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; Predicted GTPases YP_004279521.1 Uncharacterized protein conserved in bacteria YP_004279522.1 NnrU protein; Predicted membrane protein YP_004279523.1 glycoside hydrolase/deacetylase, beta/alpha-barrel YP_004279524.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; ABC-type long-chain fatty acid transport system, fused permease and ATPase components YP_004279525.1 Protein of unknown function DUF1228; Permeases of the major facilitator superfamily YP_004279526.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_004279527.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004279528.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004279529.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004279530.1 Xanthine dehydrogenase, small subunit, bacteria; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A YP_004279531.1 Xanthine dehydrogenase, molybdopterin binding subunit; Xanthine dehydrogenase, molybdopterin-binding subunit B YP_004279532.1 Xanthine dehydrogenase accessory protein XdhC; Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family YP_004279533.1 LysR substrate binding domain; Transcriptional regulator YP_004279535.1 Protein of unknown function DUF989; Predicted membrane protein YP_004279536.1 Catalyzes the deamination of guanine; Cytosine deaminase and related metal-dependent hydrolases YP_004279537.1 Protein of unknown function DUF81; Predicted permeases YP_004279539.1 Alpha-hydroxy acid dehydrogenase, FMN-dependent; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases YP_004279540.1 Small Multidrug Resistance protein; Membrane transporters of cations and cationic drugs YP_004279541.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004279542.1 Beta-lactamase-type transpeptidase fold YP_004279543.1 Phosphoesterase MJ0912; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases YP_004279544.1 HIUase/Transthyretin family; Transthyretin-like protein YP_004279545.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_004279546.1 Protein of unknown function DUF86; Uncharacterized conserved protein YP_004279547.1 DNA polymerase, beta-like region; Predicted nucleotidyltransferases YP_004279548.1 OHCU decarboxylase; Uncharacterized protein conserved in bacteria YP_004279549.1 glycoside hydrolase/deacetylase, beta/alpha-barrel; Predicted xylanase/chitin deacetylase YP_004279550.1 Protein of unknown function DUF1045 YP_004279551.1 FAD dependent oxidoreductase; glycine/D-amino acid oxidases (deaminating) YP_004279552.1 hypothetical protein; Uncharacterized conserved protein YP_004279553.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; FOG: PAS/PAC domain YP_004279554.1 DEAD-like helicase, N-terminal; Superfamily II DNA and RNA helicases YP_004279555.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004279556.1 DoxX; Predicted membrane protein YP_004279557.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004279558.1 Protein of unknown function DUF6, transmembrane YP_004279559.1 Protein of unknown function DUF404, bacteria N-terminal; Uncharacterized conserved protein YP_004279560.1 Protein of unknown function DUF403, bacteria; Uncharacterized protein conserved in bacteria YP_004279561.1 Bacterial transglutaminase-like N-terminal region; Transglutaminase-like enzymes, cysteine proteases YP_004279562.1 methyltransferase type 11; SAM-dependent methyltransferases YP_004279563.1 GCN5-related N-acetyltransferase; Predicted acetyltransferase YP_004279564.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Lactoylglutathione lyase and related lyases YP_004279565.1 Phosphoglycerate mutase family YP_004279566.1 Protein of unknown function DUF1238; Uncharacterized protein conserved in bacteria YP_004279567.1 Bacterial inner-membrane translocator; ABC-type xylose transport system, permease component YP_004279568.1 ABC transporter related; ABC-type sugar transport system, ATPase component YP_004279569.1 xylF: D-xylose ABC transporter, substrate-binding protein; ABC-type xylose transport system, periplasmic component YP_004279571.1 LysR substrate binding domain; Transcriptional regulator YP_004279574.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004279576.1 Bacterial chemotaxis sensory transducer, methyl-accepting chemotaxis protein (MCP) signaling domain YP_004279577.1 Homocysteine S-methyltransferase; Homocysteine/selenocysteine methylase (S- methylmethionine-dependent) YP_004279578.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004279579.1 Binding-protein-dependent transport systems inner membrane component; ABC-type arginine transport system, permease component YP_004279580.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004279581.1 ABC transporter related; ABC-type polar amino acid transport system, ATPase component YP_004279582.1 O-antigen polymerase; Lipid A core - O-antigen ligase and related enzymes YP_004279585.1 glycoside hydrolase, catalytic core; Beta-1,4-xylanase YP_004279586.1 glycosyl transferase, family 2; glycosyltransferases involved in cell wall biogenesis YP_004279587.1 glycosyl transferase, family 2; glycosyltransferases involved in cell wall biogenesis YP_004279589.1 glycosyl transferase WecB/TagA/CpsF; Teichoic acid biosynthesis proteins YP_004279591.1 Lipopolysaccharide biosynthesis; Uncharacterized protein involved in exopolysaccharide biosynthesis YP_004279593.1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004279594.1 Bacterial-like globin; Truncated hemoglobins YP_004279595.1 Protein of unknown function DUF423; Uncharacterized small membrane protein YP_004279598.1 Transcriptional regulator, YcdC, C-terminal; Transcriptional regulator YP_004279599.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; Acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases YP_004279600.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; Dihydroorotase and related cyclic amidohydrolases YP_004279601.1 NUDIX hydrolase, core; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004279602.1 nitrate ABC transporter ATP-binding proteins C and D; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004279603.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004279604.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004279605.1 ABC transporter substrate-binding protein (nitrate/sulfonate/taurine/bicarbonate); ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004279606.1 Membrane-fusion protein YP_004279607.1 AcrB/AcrD/AcrF family; Cation/multidrug efflux pump YP_004279608.1 Cyclic nucleotide-binding domain; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_004279609.1 Metallo-beta-lactamase superfamily; Zn-dependent hydrolases, including glyoxylases YP_004279610.1 [NiFe]-hydrogenase/urease maturation factor, Ni(2+)-binding; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase YP_004279611.1 Urease accessory protein UreF YP_004279612.1 Nickel metallochaperone UreE YP_004279613.1 Redoxin YP_004279614.1 Conserved hypothetical protein CHP02117 YP_004279615.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Urea amidohydrolase (urease) subunit alpha YP_004279617.1 Protein of unknown function DUF1311; Uncharacterized protein conserved in bacteria YP_004279618.1 Glutathione-dependent formaldehyde-activating, GFA; Uncharacterized conserved protein YP_004279619.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; Urea amidohydrolase (urease) beta subunit YP_004279620.1 Protein of unknown function DUF1272; Uncharacterized protein conserved in bacteria YP_004279621.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Urea amidohydrolase (urease) gamma subunit YP_004279622.1 Urease accessory protein UreH YP_004279623.1 Poly(3-hydroxybutyrate) depolymerase YP_004279624.1 ABC transporter nucleotide-binding protein/ATPase (urea/amide); ABC-type branched-chain amino acid transport systems, ATPase component YP_004279625.1 ABC transporter nucleotide-binding protein/ATPase (urea/amide); Uncharacterized ABC-type transport system, ATPase component YP_004279626.1 ABC transporter transmembrane protein (urea/amide); ABC-type branched-chain amino acid transport system, permease component YP_004279627.1 ABC transporter transmembrane protein (urea/amide); Branched-chain amino acid ABC-type transport system, permease components YP_004279628.1 ABC transporter substrate-binding protein (urea/amide); ABC-type branched-chain amino acid transport systems, periplasmic component YP_004279630.1 Glutamine synthetase, catalytic domain; Glutamine synthetase YP_004279631.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004279632.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004279633.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004279634.1 Predicted ATPase YP_004279635.1 Extracellular ligand-binding receptor; ABC-type branched-chain amino acid transport systems, periplasmic component YP_004279637.1 ABC transporter; ABC-type branched-chain amino acid transport systems, ATPase component YP_004279638.1 ABC transporter related; ABC-type branched-chain amino acid transport systems, ATPase component YP_004279639.1 ABC transporter related; ABC-type branched-chain amino acid transport systems, ATPase component YP_004279640.1 Branched-chain amino acid transport system / permease component; ABC-type branched-chain amino acid transport system, permease component YP_004279641.1 Branched-chain amino acid transport system / permease component; Branched-chain amino acid ABC-type transport system, permease components YP_004279642.1 3'(2'),5'-bisphosphate nucleotidase; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'- phosphatase YP_004279643.1 Tumour necrosis factor-like YP_004279644.1 Protein of unknown function DUF1153 YP_004279645.1 Predicted acetyltransferase YP_004279648.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004279649.1 GCN5-related N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004279650.1 Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II; Predicted dienelactone hydrolase YP_004279651.1 Acetyltransferases, including N-acetylases of ribosomal proteins YP_004279652.1 Uncharacterized protein conserved in bacteria YP_004279653.1 Uncharacterised conserved protein UCP033924, Protein of unknown function (DUF1134); Uncharacterized protein conserved in bacteria YP_004279655.1 tRNA/rRNA methyltransferase, SpoU; rRNA methylases YP_004279657.1 Pseudouridine synthase, RluD; Pseudouridylate synthases, 23S RNA-specific YP_004279660.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) YP_004279662.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; Adenylosuccinate synthase YP_004279663.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004279664.1 transglutaminase-like cysteine peptidase, BTLCP; Predicted transglutaminase-like cysteine proteinase YP_004279666.1 Lytic transglycosylase-like, catalytic; Uncharacterized protein conserved in bacteria YP_004279667.1 Predicted esterase YP_004279668.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004279669.1 Siderophore-interacting protein YP_004279670.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Uracil DNA glycosylase YP_004279671.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004279672.1 Protein of unknown function DUF454; Uncharacterized protein conserved in bacteria YP_004279673.1 ABC transporter nucleotide-binding protein/ATPase (hemin); ABC-type hemin transport system, ATPase component YP_004279674.1 Bacterial transport system permease; ABC-type Fe3+-siderophore transport system, permease component YP_004279675.1 Periplasmic binding protein; ABC-type hemin transport system, periplasmic component YP_004279676.1 Dimeric alpha-beta barrel, Antibiotic biosynthesis monooxygenase; Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides YP_004279677.1 Protein of unknown function DUF1008; heme iron utilization protein YP_004279678.1 Protein of unknown function DUF306, Meta and HslJ; Uncharacterized protein conserved in bacteria YP_004279679.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; Formyltetrahydrofolate hydrolase YP_004279681.1 Histidine kinase, Two-component sensor kinase N-terminal; Signal transduction histidine kinase YP_004279682.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004279683.1 Prokaryotic extracellular metal-binding protein; ABC-type Fe3+ transport system, periplasmic component YP_004279684.1 Bordetella uptake gene (bug) product; Uncharacterized protein conserved in bacteria YP_004279686.1 Protein of unknown function DUF112, transmembrane; Uncharacterized protein conserved in bacteria YP_004279688.1 Periplasmic binding protein; ABC-type enterochelin transport system, periplasmic component YP_004279689.1 Bacterial transport system permease; ABC-type enterochelin transport system, permease component YP_004279690.1 ABC transporter transmembrane protein; ABC-type enterochelin transport system, permease component YP_004279691.1 ABC transporter related; ABC-type enterochelin transport system, ATPase component YP_004279692.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA-binding ferritin-like protein (oxidative damage protectant) YP_004279694.1 methyl-accepting chemotaxis protein (MCP) signaling domain YP_004279695.1 Aldo/keto reductase family; Aldo/keto reductases, related to diketogulonate reductase YP_004279696.1 Major facilitator superfamily; Arabinose efflux permease YP_004279697.1 LysR, substrate-binding; Transcriptional regulator YP_004279698.1 LysR substrate binding domain; Transcriptional regulator YP_004279699.1 alpha/beta hydrolase fold; Esterase/lipase YP_004279700.1 Membrane-fusion protein YP_004279701.1 RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; Cation/multidrug efflux pump YP_004279703.1 Endonuclease/Exonuclease/phosphatase family; Metal-dependent hydrolase YP_004279704.1 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthases and related enzymes YP_004279705.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; Pyridoxal/pyridoxine/pyridoxamine kinase YP_004279707.1 Membrane-bound lytic murein transglycosylase B YP_004279708.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_004279709.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279710.1 forms a tetramer composed of 2 subunit alphas and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD/NADP transhydrogenase subunit alpha YP_004279711.1 NAD(P)+ transhydrogenase beta chain; NAD/NADP transhydrogenase beta subunit YP_004279712.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004279713.1 Nitroreductase family; Nitroreductase YP_004279714.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004279715.1 Endoribonuclease L-PSP/chorismate mutase-like; translation initiation inhibitor, yjgF family YP_004279716.1 Isochorismatase family; Amidases related to nicotinamidase YP_004279717.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004279718.1 Haem oxygenase YP_004279719.1 Dihydrodipicolinate synthetase family; Dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004279720.1 GntR, C-terminal; Transcriptional regulators YP_004279721.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004279722.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004279723.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004279724.1 ABC transporter nucleotide-binding protein/ATPase (sugar); ABC-type sugar transport systems, ATPase components YP_004279725.1 Carbohydrate/purine kinase; Sugar kinases, ribokinase family YP_004279726.1 Peptidase family S58; L-aminopeptidase/D-esterase YP_004279727.1 catalyzes the transamination of D-amino acids and their alpha-keto acids; Branched-chain amino acid aminotransferase/4- amino-4-deoxychorismate lyase YP_004279728.1 Bacterial regulatory helix-turn-helix protein, lysR family; Transcriptional regulator YP_004279729.1 Beta-lactamase-type transpeptidase fold; Beta-lactamase class C and other penicillin binding proteins YP_004279730.1 ABC transporter nucleotide-binding protein/ATPase (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004279731.1 ABC transporter nucleotide-binding protein/ATPase (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004279732.1 ABC transporter transmembrane protein (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004279733.1 ABC transporter transmembrane protein (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004279734.1 ABC transporter substrate-binding protein (dipeptide); ABC-type dipeptide transport system, periplasmic component YP_004279735.1 Membrane dipeptidase (Peptidase family M19); Zn-dependent dipeptidase, microsomal dipeptidase homolog YP_004279737.1 Protein of unknown function DUF470; Uncharacterized conserved protein YP_004279738.1 Type IV secretory pathway, VirJ component YP_004279739.1 DNA breaking-rejoining enzyme, catalytic core YP_004279740.1 Protein of unknown function DUF1217 YP_004279741.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279742.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the reactions based on sequence and structure similarity; Uncharacterized protein conserved in bacteria YP_004279743.1 chlorocatechol 1,2-dioxygenase; Protocatechuate 3,4-dioxygenase beta subunit YP_004279744.1 Iron-containing alcohol dehydrogenase; Alcohol dehydrogenase, class IV YP_004279745.1 Amidohydrolase 2; Predicted metal-dependent hydrolase of the TIM- barrel fold YP_004279746.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004279747.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004279748.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004279750.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004279751.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004279752.1 Homeodomain-related; Transcriptional regulator YP_004279753.1 NADH:flavin oxidoreductase / NADH oxidase family; NADH:flavin oxidoreductases, Old Yellow Enzyme family YP_004279754.1 ABC transporter nucleotide-binding protein/ATPase (iron); ABC-type spermidine/putrescine transport systems, ATPase components YP_004279755.1 Binding-protein-dependent transport systems inner membrane component; ABC-type Fe3+ transport system, permease component YP_004279756.1 Bacterial extracellular solute-binding protein, family 1; ABC-type Fe3+ transport system, periplasmic component YP_004279757.1 Bacterial extracellular solute-binding protein, family 1; ABC-type Fe3+ transport system, periplasmic component YP_004279758.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004279759.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004279760.1 Bacterial chemotaxis sensory transducer YP_004279761.1 Cobyrinic acid a,c-diamide synthase; ATPases involved in chromosome partitioning YP_004279762.1 Chemotaxis response regulator, CheB type; Chemotaxis response regulator containing a CheY- like receiver domain and a methylesterase domain YP_004279763.1 CheR methyltransferase, SAM binding domain; methylase of chemotaxis methyl-accepting proteins YP_004279764.1 CheW-like protein; Chemotaxis signal transduction protein YP_004279765.1 Bacterial chemotaxis sensory transducer, methyl-accepting chemotaxis protein (MCP) signaling domain YP_004279766.1 CheW-like protein; Chemotaxis signal transduction protein YP_004279767.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Chemotaxis protein histidine kinase and related kinases YP_004279768.1 Response regulator receiver domain; FOG: CheY-like receiver YP_004279770.1 CheY-like; Response regulator containing a CheY-like receiver domain and an HD-GYP domain YP_004279771.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004279772.1 FMN-binding split barrel, related, Flavin reductase like domain; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004279773.1 LysR, substrate-binding; Transcriptional regulator YP_004279774.1 Rieske [2Fe-2S] domain; Phenylpropionate dioxygenase and related ring- hydroxylating dioxygenases, large terminal subunit YP_004279775.1 ABC transporter nucleotide-binding protein/ATPase (nopaline); ABC-type histidine transport system, ATPase component YP_004279776.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004279777.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004279778.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004279779.1 FAD linked oxidase, C-terminal, FAD binding domain; FAD/FMN-containing dehydrogenases YP_004279780.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate and L-glutamate from L-histidinol phosphate and 2-oxoglutarate; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase YP_004279781.1 oxidoreductase NAD-binding domain; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 YP_004279783.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase YP_004279784.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; Transcriptional regulator YP_004279785.1 HlyD family secretion protein; Membrane-fusion protein YP_004279786.1 AcrB/AcrD/AcrF family; silver efflux pump YP_004279787.1 RND efflux system, outer membrane lipoprotein, NodT; Outer membrane protein YP_004279788.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; Translation elongation factor P (EF- P)/translation initiation factor 5A (eIF-5A) YP_004279789.1 Aminoacyl-tRNA synthetase, class II (D, K and N); Lysyl-tRNA synthetase (class II) YP_004279790.1 L-lysine 2,3-aminomutase; Lysine 2,3-aminomutase YP_004279793.1 Dimeric alpha-beta barrel; Transcriptional regulators YP_004279794.1 LysR substrate binding domain; Transcriptional regulator YP_004279795.1 glycine/D-amino acid oxidases (deaminating) YP_004279796.1 Bacterial extracellular solute-binding protein, family 1; ABC-type molybdate transport system, periplasmic component YP_004279797.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; ABC-type molybdate transport system, permease component YP_004279798.1 Molybdate ABC transporter ATP-binding protein; ABC-type molybdate transport system, ATPase component YP_004279799.1 Bacterial regulatory helix-turn-helix protein, lysR family; N-terminal domain of molybdenum-binding protein YP_004279800.1 Peptidase S58, DmpA; L-aminopeptidase/D-esterase YP_004279801.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; Uncharacterized enzyme of thiazole biosynthesis YP_004279802.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; Sulfur transfer protein involved in thiamine biosynthesis YP_004279803.1 glycine oxidase ThiO; glycine/D-amino acid oxidases (deaminating) YP_004279804.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_004279805.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_004279806.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004279807.1 Seryl-tRNA synthetase YP_004279808.1 Protein of unknown function DUF1839 YP_004279809.1 Beta-galactosidase/beta-glucuronidase YP_004279811.1 ABC transporter related; ABC-type multidrug transport system, ATPase and permease components YP_004279812.1 Cyclic nucleotide-binding domain; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_004279813.1 Metal-dependent hydrolases of the beta- lactamase superfamily I YP_004279814.1 Adenylyl cyclase class-3/4/guanylyl cyclase; Ferredoxin YP_004279816.1 UDP-glucose/GDP-mannose dehydrogenase, dimerisation and substrate-binding; UDP-N-acetyl-D-mannosaminuronate dehydrogenase YP_004279817.1 glycosyl transferase, group 1 YP_004279818.1 glycoside hydrolase/deacetylase, beta/alpha-barrel YP_004279819.1 glycosyltransferase sugar-binding region containing DXD motif; Mannosyltransferase OCH1 and related enzymes YP_004279820.1 ABC transporter nucleotide-binding protein/ATPase (oligopeptide); ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004279821.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004279822.1 ABC transporter transmembrane protein (oligopeptide); ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004279823.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004279824.1 membrane-anchored protein, slightly; Predicted glycosyl transferase YP_004279825.1 glycosyl transferase, group 1; glycosyltransferase YP_004279826.1 membrane-anchored protein, slightly; Predicted glycosyl transferase YP_004279827.1 CutC family; Uncharacterized protein involved in copper resistance YP_004279828.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279829.1 Microcystin LR degradation protein MlrC; Uncharacterized conserved protein YP_004279830.1 glycosyl hydrolase family 20, catalytic domain; N-acetyl-beta-hexosaminidase YP_004279831.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004279832.1 Sugar isomerase (SIS); Transcriptional regulators YP_004279834.1 ABC transporter nucleotide-binding protein/ATPase (maltose/maltodextrin); ABC-type sugar transport systems, ATPase components YP_004279835.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004279836.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004279837.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004279838.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004279840.1 UbiC transcription regulator-associated; Transcriptional regulators YP_004279841.1 Sugar isomerase (SIS); Predicted phosphosugar isomerases YP_004279843.1 ROK family; Transcriptional regulator/sugar kinase YP_004279844.1 Monooxygenase, FAD-binding; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_004279845.1 Phosphatidic acid phosphatase type 2-like; Membrane-associated phospholipid phosphatase YP_004279846.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_004279847.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 7-keto-8-aminopelargonate synthetase and related enzymes YP_004279848.1 Rickettsia 17 kDa surface antigen YP_004279849.1 Bacterial surface antigen (D15) YP_004279850.1 Protein of unknown function DUF490; Uncharacterized protein conserved in bacteria YP_004279851.1 CheW-like protein; Chemotaxis signal transduction protein YP_004279852.1 methyl-accepting chemotaxis protein (MCP) signaling domain YP_004279853.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; Uncharacterized protein required for formate dehydrogenase activity YP_004279854.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) YP_004279855.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1-type ATP synthase, beta subunit YP_004279856.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1-type ATP synthase, gamma subunit YP_004279857.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1-type ATP synthase, subunit alpha YP_004279858.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) YP_004279860.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; Primosomal protein N' (replication factor Y) - superfamily II helicase YP_004279861.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; Site-specific recombinase XerC YP_004279862.1 GumN protein; Uncharacterized protein conserved in bacteria YP_004279864.1 Cytochrome B561, bacterial; Cytochrome B561 YP_004279865.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes YP_004279866.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004279867.1 Predicted membrane protein YP_004279868.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes YP_004279869.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes YP_004279870.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; Succinyl-CoA synthetase, subunit alpha YP_004279871.1 catalyzes the interconversion of succinyl-CoA and succinate; Succinyl-CoA synthetase, beta subunit YP_004279872.1 Catalyzes the reversible oxidation of malate to oxaloacetate; Malate/lactate dehydrogenases YP_004279873.1 AFG1-like ATPase; Predicted ATPase YP_004279874.1 Outer membrane lipoprotein, Omp19, bacterial YP_004279875.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are; Succinate dehydrogenase/fumarate reductase, Fe- S protein subunit YP_004279876.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit YP_004279877.1 Succinate dehydrogenase, cytochrome b subunit; Succinate dehydrogenase, hydrophobic anchor subunit YP_004279878.1 Succinate dehydrogenase, cytochrome b560 subunit; Succinate dehydrogenase/fumarate reductase, cytochrome b subunit YP_004279880.1 Ribosomal L11 methyltransferase; Predicted methyltransferase YP_004279881.1 Protein of unknown function DUF55; Uncharacterized conserved protein YP_004279882.1 Dimeric alpha-beta barrel; Uncharacterized protein conserved in bacteria YP_004279883.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; glycerol-3-phosphate dehydrogenase YP_004279884.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; Metal-dependent proteases with possible chaperone activity YP_004279885.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_004279886.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; Uroporphyrinogen-III synthase YP_004279887.1 Uncharacterized protein conserved in bacteria YP_004279888.1 HemY protein N-terminus; Uncharacterized enzyme of heme biosynthesis YP_004279889.1 Protein of unknown function DUF1332; Uncharacterized protein conserved in bacteria YP_004279890.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group; GMP synthase - Glutamine amidotransferase domain YP_004279891.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279892.1 Protein of unknown function YGGT YP_004279893.1 Protein of unknown function DUF167; Uncharacterized conserved protein YP_004279894.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_004279895.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Sortase and related acyltransferases YP_004279896.1 Predicted membrane GTPase involved in stress response YP_004279897.1 Zn-dependent oligopeptidases YP_004279899.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004279900.1 Drug resistance transporter Bcr/CflA subfamily; Permeases of the major facilitator superfamily YP_004279901.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_004279902.1 Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenases of various substrate specificities YP_004279903.1 Lysine exporter protein (LYSE/YGGA); threonine efflux protein YP_004279904.1 ABC transporter nucleotide-binding protein/ATPase; ABC-type uncharacterized transport system, ATPase component YP_004279905.1 Bacterial inner-membrane translocator; ABC-type uncharacterized transport system, permease component YP_004279906.1 ABC-type uncharacterized transport system, periplasmic component YP_004279907.1 Radical SAM superfamily; Predicted Fe-S-cluster redox enzyme YP_004279909.1 Protein of unknown function DUF1232; Uncharacterized conserved protein YP_004279910.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; Pterin-4a-carbinolamine dehydratase YP_004279911.1 Protein-tyrosine phosphatase, low molecular weight; Protein-tyrosine-phosphatase YP_004279912.1 RNA ligase/cyclic nucleotide phosphodiesterase, 2',5' RNA ligase family YP_004279913.1 GDSL-like Lipase/Acylhydrolase; Lysophospholipase L1 and related esterases YP_004279914.1 ABC transporter nucleotide-binding protein/ATPase; Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component YP_004279915.1 Protein of unknown function DUF214, permase ; Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component YP_004279916.1 Protein of unknown function UPF0005; Integral membrane protein, interacts with FtsH YP_004279918.1 Protein of unknown function DUF1223; Uncharacterized secreted protein YP_004279919.1 Catalyzes the conversion of citrate to isocitrate; Aconitase A YP_004279920.1 ATP-binding protein; required for proper cytochrome c maturation; ABC-type transport system involved in cytochrome c biogenesis, ATPase component YP_004279921.1 Cytochrome c-type biogenesis protein CcmB; ABC-type transport system involved in cytochrome c biogenesis, permease component YP_004279922.1 Cytochrome c-type biogenesis protein CcmC; ABC-type transport system involved in cytochrome c biogenesis, permease component YP_004279924.1 Periplasmic protein thiol:disulphide oxidoreductase DsbE; Thiol-disulfide isomerase and thioredoxins YP_004279925.1 diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004279927.1 Involved in cell division; probably involved in intracellular septation YP_004279928.1 Signal recognition particle GTPase YP_004279929.1 Protein of unknown function UPF0004, RNA modification enzyme, MiaB family; 2-methylthioadenine synthetase YP_004279930.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_004279931.1 Beta-lactamase-like; Predicted Zn-dependent hydrolases of the beta- lactamase fold YP_004279932.1 Signal recognition particle GTPase YP_004279933.1 catalyzes the interconversion of chorismate to prephenate YP_004279934.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; Ribosomal protein S16 YP_004279935.1 Essential for efficient processing of 16S rRNA; RimM protein, required for 16S rRNA processing YP_004279936.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA-(guanine-N1)-methyltransferase YP_004279937.1 Protein of unknown function DUF81; Predicted permeases YP_004279938.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; Ribosomal protein L19 YP_004279939.1 ABC transporter nucleotide-binding protein/ATPase (protein); ABC-type protease/lipase transport system, ATPase and permease components YP_004279940.1 Type I secretion membrane fusion protein, HlyD; Membrane-fusion protein YP_004279941.1 RTX toxins and related Ca2+-binding proteins YP_004279942.1 Transposase IS116/IS110/IS902 family; Transposase and inactivated derivatives YP_004279943.1 Serralysin-like metalloprotease, C-terminal; RTX toxins and related Ca2+-binding proteins YP_004279944.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279946.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; 3-isopropylmalate dehydratase large subunit YP_004279947.1 Peptidase M48, Ste24p; Zn-dependent protease YP_004279949.1 ABC transporter nucleotide-binding protein/ATPase (thiamine); ABC-type thiamine transport system, ATPase component YP_004279950.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; ABC-type Fe3+ transport system, permease component YP_004279951.1 part of the thiamine and TPP transport system tbpA-thiPQ; ABC-type thiamine transport system, periplasmic component YP_004279952.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Predicted lactoylglutathione lyase YP_004279953.1 ABC transporter nucleotide-binding protein/ATPase; ATPase components of ABC transporters with duplicated ATPase domains YP_004279954.1 Thiamin pyrophosphokinase, catalytic domain; Thiamine pyrophosphokinase YP_004279955.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; Homoserine trans-succinylase YP_004279956.1 glycoside hydrolase-type carbohydrate-binding, subgroup; Galactose mutarotase and related enzymes YP_004279957.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; Membrane carboxypeptidase (penicillin-binding protein) YP_004279958.1 Terpenoid synthase; Geranylgeranyl pyrophosphate synthase YP_004279959.1 Outer membrane protein, OmpA/MotB, C-terminal; Outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_004279960.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis YP_004279961.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004279962.1 Bacterial regulatory proteins, deoR family; Transcriptional regulators of sugar metabolism YP_004279963.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; Biotin carboxylase YP_004279964.1 Bacterial regulatory proteins, luxR family; DNA-binding HTH domain-containing proteins YP_004279965.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; ABC-type multidrug transport system, ATPase and permease components YP_004279966.1 Six-hairpin glycosidase-like; Cellobiose phosphorylase YP_004279967.1 Peptidase M20D, amidohydrolase; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004279968.1 FAD dependent oxidoreductase; Predicted dehydrogenase YP_004279969.1 Pyridoxal phosphate-dependent enzyme, beta subunit YP_004279970.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Dihydroxyacid dehydratase/phosphogluconate dehydratase YP_004279971.1 3-hydroxyacid dehydrogenase/reductase; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_004279972.1 NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerases YP_004279973.1 FAD linked oxidase, C-terminal; FAD/FMN-containing dehydrogenases YP_004279974.1 GntR, C-terminal; Transcriptional regulators YP_004279975.1 Fumarylacetoacetase, C-terminal-related; Fumarylacetoacetate (FAA) hydrolase YP_004279976.1 Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP-type C4-dicarboxylate transport system, small permease component YP_004279977.1 TRAP C4-dicarboxylate transport system permease DctM subunit, DctM-like transporters; TRAP-type C4-dicarboxylate transport system, large permease component YP_004279978.1 Bacterial extracellular solute-binding protein, family 7; TRAP-type C4-dicarboxylate transport system, periplasmic component YP_004279979.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases YP_004279980.1 Protein of unknown function DUF1013; Uncharacterized protein conserved in bacteria YP_004279981.1 Predicted pyridoxal phosphate-dependent enzyme, YBL036C type, TIGR00044: conserved hypothetical protein TIGR0004; Predicted enzyme with a TIM-barrel fold YP_004279982.1 leucine-tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_004279983.1 Predicted secreted (periplasmic) protein YP_004279984.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III, delta subunit YP_004279985.1 4Fe-4S ferredoxin, iron-sulphur binding YP_004279986.1 RNA-binding S4; Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit YP_004279987.1 DNA/RNA helicase, C-terminal; Superfamily II DNA and RNA helicases YP_004279988.1 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, FAD binding domain; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_004279989.1 Acyl-CoA thioesterase YP_004279990.1 Nitrogen regulatory PII-like, alpha/beta YP_004279991.1 Ammonium Transporter Family; Ammonia permease YP_004279992.1 Cell division FtsK/SpoIIIE; DNA segregation ATPase FtsK/SpoIIIE and related proteins YP_004279994.1 Outer membrane lipoprotein carrier protein LolA; Outer membrane lipoprotein-sorting protein YP_004279995.1 Endonuclease/Exonuclease/phosphatase family; Exonuclease III YP_004279996.1 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_004279997.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004279998.1 Uncharacterized protein conserved in bacteria YP_004279999.1 Transcription factor CarD; Transcriptional regulators, similar to M. xanthus CarD YP_004280000.1 Bacterial NAD-glutamate dehydrogenase; NAD-specific glutamate dehydrogenase YP_004280001.1 Major facilitator superfamily MFS-1; Permeases of the major facilitator superfamily YP_004280002.1 Polyhydroxyalkanoate synthesis repressor PhaR; Uncharacterized protein conserved in bacteria YP_004280003.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_004280004.1 poly-beta-hydroxybutyrate biosynthesis; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280005.1 BFD-like [2Fe-2S]-binding region YP_004280006.1 Bacterioferritin (cytochrome b1) YP_004280007.1 hydrolyzes diadenosine polyphosphate; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004280008.1 Protein of unknown function DUF610, YibQ; Uncharacterized protein conserved in bacteria YP_004280009.1 Peptidase S41A, C-terminal protease; Periplasmic protease YP_004280010.1 Peptidase family M23; Membrane-bound metallopeptidase YP_004280011.1 Protein of unknown function DUF163; Uncharacterized conserved protein YP_004280012.1 Domain of unknown function DUF143; Uncharacterized homolog of plant Iojap protein YP_004280013.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_004280014.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_004280015.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_004280016.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Predicted GTPase YP_004280017.1 GCN5-related N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004280018.1 GCN5-related N-acetyltransferase, Acetyltransferase (GNAT) family; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004280019.1 involved in the peptidyltransferase reaction during translation; Ribosomal protein L27 YP_004280020.1 Ribosomal protein L21 YP_004280021.1 Protein of unknown function DUF1025; Uncharacterized protein conserved in bacteria YP_004280022.1 Uncharacterized conserved small protein YP_004280023.1 citrate lyase, beta subunit; Citrate lyase beta subunit YP_004280025.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_004280026.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; Isocitrate/isopropylmalate dehydrogenase YP_004280027.1 Di-haem cytochrome c peroxidase; Cytochrome c peroxidase YP_004280028.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_004280029.1 Tetrapyrrole (Corrin/Porphyrin) methylases; Uroporphyrinogen-III methylase YP_004280030.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; Cobalamin biosynthesis protein CbiD YP_004280031.1 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; Precorrin-4 methylase YP_004280032.1 Cobalamin (vitamin B12) biosynthesis CbiG, core; Cobalamin biosynthesis protein CbiG YP_004280033.1 Cobalamin (vitamin B12) biosynthesis CobL, precorrin-6Y C5,15-methyltransferase; Precorrin-6B methylase 2 YP_004280034.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Precorrin-6x reductase YP_004280035.1 catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Precorrin-3B methylase YP_004280036.1 catalyzes the formation of precorrin-3 from precorrin-2; Precorrin-2 methylase YP_004280037.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Precorrin isomerase YP_004280038.1 Cobalamin (vitamin B12) biosynthesis CobG-like; Sulfite reductase, beta subunit (hemoprotein) YP_004280039.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Cobalamin biosynthesis protein CobN and related Mg-chelatases YP_004280040.1 Cobalamin (vitamin B12) biosynthesis CobW; GTPases (G3E family) YP_004280041.1 Protein of unknown function DUF1636; Predicted metal-binding protein YP_004280042.1 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin; ATP:corrinoid adenosyltransferase YP_004280043.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_004280044.1 Cobalamin (vitamin B12) biosynthesis CbiB, CobD/Cbib protein; Cobalamin biosynthesis protein CobD/CbiB YP_004280045.1 cobalamin biosynthetic protein; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase YP_004280046.1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004280047.1 RProtein of unknown function (DUF718); Uncharacterized conserved protein YP_004280048.1 Mannitol dehydrogenase, C-terminal; Mannitol-1-phosphate/altronate dehydrogenases YP_004280049.1 Alcohol dehydrogenase superfamily, zinc-containing; Threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004280050.1 Amidohydrolase 2; Predicted metal-dependent hydrolase of the TIM- barrel fold YP_004280051.1 Aldo/keto reductase; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004280052.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004280053.1 ABC transporter transmembrane protein (ribose); Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004280054.1 ABC transporter nucleotide-binding protein/ATPase (ribose); ABC-type sugar transport system, ATPase component YP_004280055.1 GntR, C-terminal; Transcriptional regulators YP_004280056.1 D-galactarate dehydratase/Altronate hydrolase, C-terminal; Altronate dehydratase YP_004280057.1 involved in de novo purine biosynthesis; AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) YP_004280058.1 Heparinase II/III-like protein; Uncharacterized protein conserved in bacteria YP_004280059.1 Bacterial Fmu /eukaryotic nucleolar NOL1/Nop2p; tRNA and rRNA cytosine-C5-methylases YP_004280060.1 metalloprotease; Zn-dependent protease with chaperone function YP_004280061.1 Protein of unknown function DUF1674 YP_004280062.1 Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain YP_004280063.1 ATPases involved in chromosome partitioning YP_004280064.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division YP_004280065.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; Flavin-dependent tRNA uridine 5- carboxymethylaminomethyl modification enzyme GidA YP_004280066.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; Predicted GTPase YP_004280067.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; Transcription termination factor YP_004280068.1 Uncharacterised protein family UPF0093; Predicted membrane protein YP_004280069.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; Uroporphyrinogen-III decarboxylase YP_004280070.1 cobyrinic acid a,c-diamide synthase, CobQ/CobB/MinD/ParA nucleotide binding domain; ATPases involved in chromosome partitioning YP_004280071.1 ParB-like partition protein; stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain YP_004280073.1 CoA-transferase family III; Predicted acyl-CoA transferases/carnitine dehydratase YP_004280074.1 Choline dehydrogenase and related flavoproteins YP_004280075.1 LysR substrate binding domain; transcriptional regulator YP_004280076.1 LysR substrate binding domain; transcriptional regulator YP_004280077.1 Lactoylglutathione lyase and related lyases YP_004280078.1 Short-chain alcohol dehydrogenase of unknown specificity YP_004280079.1 Dimeric alpha-beta barrel; Uncharacterized conserved protein YP_004280080.1 Short-chain alcohol dehydrogenase of unknown specificity YP_004280083.1 protein of unknown function DUF159; Uncharacterized conserved protein YP_004280084.1 LysR substrate binding domain; transcriptional regulator YP_004280085.1 NADP oxidoreductase, coenzyme F420-dependent; Predicted dinucleotide-binding enzymes YP_004280086.1 Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type DNA-binding domain-containing proteins YP_004280087.1 Short-chain alcohol dehydrogenase of unknown specificity YP_004280089.1 Fic family protein YP_004280092.1 pyruvate/phosphoenolpyruvate kinase, catalytic core, HpcH/HpaI aldolase/citrate lyase family YP_004280093.1 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; 2-keto-4-pentenoate hydratase YP_004280094.1 Intradiol ring-cleavage dioxygenase, core; Protocatechuate 3,4-dioxygenase subunit beta YP_004280095.1 Bacterial regulatory proteins, gntR family; transcriptional regulators YP_004280096.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004280102.1 DNA breaking-rejoining enzyme, catalytic core; Site-specific recombinase XerD YP_004280103.1 protein of unknown function DUF1612 YP_004280105.1 NAD-dependent protein deacetylases, SIR2 family YP_004280106.1 protein of unknown function DUF1863 YP_004280107.1 Toll-Interleukin receptor YP_004280108.1 polynucleotidyl transferase, ribonuclease H fold; Uncharacterized protein containing piwi/argonaute domain YP_004280111.1 Predicted ATPases YP_004280112.1 NACHT nucleoside triphosphatase; Predicted NTPase (NACHT family) YP_004280113.1 Major facilitator superfamily, efflux_EmrB: drug resistance MFS transporter drug:H+ antiporter-1 (14 Spanner) (DHA2) family; Permeases of the major facilitator superfamily YP_004280114.1 HlyD family secretion protein, 8a0101: efflux pump membrane protein; Multidrug resistance efflux pump YP_004280115.1 LysR substrate binding domain; transcriptional regulator YP_004280116.1 LysR substrate binding domain; transcriptional regulator YP_004280119.1 carboxymuconolactone decarboxylase family; Uncharacterized homolog of gamma- carboxymuconolactone decarboxylase subunit YP_004280121.1 Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type DNA-binding domain-containing proteins YP_004280122.1 adenylyl cyclase class-3/4/guanylyl cyclase; adenylate cyclase, family 3 (some proteins contain HAMP domain) YP_004280123.1 Short-chain dehydrogenase/reductase SDR; Short-chain alcohol dehydrogenase of unknown specificity YP_004280124.1 FMN-binding split barrel, related; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004280125.1 protein of unknown function DUF1330; Uncharacterized conserved protein YP_004280126.1 Dimeric alpha-beta barrel; Uncharacterized conserved protein YP_004280127.1 Short-chain dehydrogenase/reductase SDR; Short-chain alcohol dehydrogenase of unknown specificity YP_004280128.1 Short-chain dehydrogenase/reductase SDR; Short-chain alcohol dehydrogenase of unknown specificity YP_004280129.1 Surfeit locus 4-related, DoxX; Predicted membrane protein YP_004280130.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280131.1 protein of unknown function DUF1486, SnoaL-like polyketide cyclase; Predicted ester cyclase YP_004280132.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280133.1 stationary phase protein that binds TrpR repressor; Multimeric flavodoxin WrbA YP_004280134.1 transketolase, thiamine diphosphate binding domain; transketolase YP_004280135.1 transketolase, C-terminal subunit YP_004280136.1 pyridoxal phosphate-dependent transferase, major region, Aminotransferase class-III; glutamate-1-semialdehyde aminotransferase YP_004280138.1 Bacterial extracellular solute-binding protein, family 1; Spermidine/putrescine-binding periplasmic protein YP_004280139.1 Binding-protein-dependent transporters inner membrane component; ABC-type spermidine/putrescine transporter, permease component I YP_004280140.1 Binding-protein-dependent transporters inner membrane component; ABC-type spermidine/putrescine transporter, permease component II YP_004280141.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280142.1 Bacterial regulatory proteins, gntR family; transcriptional regulators YP_004280143.1 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase, aminotransferase class-III; adenosylmethionine-8-amino-7-oxononanoateaminotransferase YP_004280144.1 amidase; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases YP_004280145.1 Spermidine/putrescine ABC transporter ATP-binding subunit, ABC transporter; ABC-type sugar transporters, ATPase components YP_004280146.1 succinate-semialdehyde dehydrogenase [NADP+] protein; NAD-dependent aldehyde dehydrogenases YP_004280147.1 histone deacetylase superfamily; Deacetylases, including yeast histone deacetylase and acetoin utilization protein YP_004280148.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004280149.1 Short-chain alcohol dehydrogenase of unknown specificity YP_004280150.1 AraC family transcriptional regulator; AraC-type DNA-binding domain-containing proteins YP_004280151.1 LysR substrate binding domain; transcriptional regulator YP_004280152.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004280154.1 AraC-type transcriptional regulator N-terminus; AraC-type DNA-binding domain-containing proteins YP_004280156.1 NADP oxidoreductase, coenzyme F420-dependent; Predicted dinucleotide-binding enzymes YP_004280157.1 Cupin, RmlC-type; Pirin-related protein YP_004280158.1 LysR substrate binding domain; transcriptional regulator YP_004280159.1 transposase and inactivated derivatives YP_004280160.1 pyruvate/phosphoenolpyruvate kinase, catalytic core; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_004280162.1 Bacterial regulatory proteins, AsnC/Lrp; transcriptional regulators YP_004280163.1 Bacterial extracellular solute-binding protein, family 5, nickel_nikA: nickel ABC transporter periplasmic nickel-binding protein; ABC-type dipeptide transporter, periplasmic component YP_004280164.1 Binding-protein-dependent transporter inner membrane component, nickel_nikB: nickel ABC transporter permease subunit NikB; ABC-type dipeptide/oligopeptide/nickel transporters, permease components YP_004280165.1 Binding-protein-dependent transporters inner membrane component, nickel_nikC: nickel ABC transporter permease subunit NikC; ABC-type dipeptide/oligopeptide/nickel transporters, permease components YP_004280166.1 nickel_nikD: nickel import ATP-binding protein NikD; ABC-type uncharacterized transporter, duplicated ATPase component YP_004280167.1 beta-lactamase-type transpeptidase fold; beta-lactamase class C and other penicillin binding proteins YP_004280168.1 Uncharacterized protein, amidase YP_004280169.1 ribonuclease E inhibitor RraA/dimethylmenaquinone methyltransferase; Demethylmenaquinone methyltransferase YP_004280172.1 thioredoxin-like fold; Uncharacterized protein conserved in bacteria containing thioredoxin-like domain YP_004280173.1 GntR, C-terminal; transcriptional regulators YP_004280175.1 oxygenase (tetracycline 6-hydroxylase) protein; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_004280176.1 LysR substrate binding domain; transcriptional regulator YP_004280177.1 alcohol dehydrogenase superfamily, zinc-containing, Zinc-binding dehydrogenase; NADPH:quinone reductase and related Zn- dependent oxidoreductases YP_004280178.1 Helix-turn-helix, HxlR type; Predicted transcriptional regulators YP_004280179.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280180.1 Bacterial regulatory proteins, tetR family; transcriptional regulator YP_004280182.1 LysR substrate binding domain; transcriptional regulator YP_004280183.1 protein of unknown function DUF1486; Ketosteroid isomerase-related protein YP_004280184.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280185.1 Aldo/keto reductase family, Kv_beta: voltage-dependent potassium channel subunit beta; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004280186.1 Ketosteroid isomerase-related protein YP_004280188.1 LysR, substrate-binding YP_004280189.1 LysR substrate binding domain; transcriptional regulator YP_004280190.1 transposase, Tn3; transposase and inactivated derivatives, TnpA family YP_004280191.1 DEAD/DEAH box helicase:Helicase, C-terminal YP_004280192.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280193.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280194.1 transcriptional regulator, Rrf2; Predicted transcriptional regulator YP_004280195.1 MscS Mechanosensitive ion channel; Small-conductance mechanosensitive channel YP_004280196.1 Cupin, RmlC-type; Uncharacterized conserved protein, contains double-stranded beta-helix domain YP_004280197.1 NAD-dependent epimerase/dehydratase; Predicted nucleoside-diphosphate-sugar epimerases YP_004280198.1 carboxymuconolactone decarboxylase family, ahpD_dom: alkylhydroperoxidase AhpD family core domain; Uncharacterized conserved protein YP_004280199.1 LysR substrate binding domain; transcriptional regulator YP_004280200.1 CheY-like, Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280201.1 histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, sensory_box: PAS domain S-box; Signal transduction histidine kinase regulating C4-dicarboxylate transporter YP_004280202.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004280203.1 beta-lactamase-like, metallo-beta-lactamase superfamily; Zn-dependent hydrolases, including glyoxylases YP_004280204.1 FMN-binding split barrel, related; Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase YP_004280205.1 protein of unknown function DUF1348; Uncharacterized protein conserved in bacteria YP_004280206.1 GCN5-related N-acetyltransferase YP_004280207.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis YP_004280208.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004280209.1 RNA polymerase sigma-70, sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004280210.1 Uncharacterized protein conserved in bacteria YP_004280211.1 alpha/beta hydrolase fold-3; esterase/lipase YP_004280212.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280213.1 Helix-turn-helix, HxlR type; Predicted transcriptional regulators YP_004280214.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; transcriptional regulator YP_004280215.1 Major facilitator superfamily; Arabinose efflux permease YP_004280216.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280217.1 Asp/Glu/Hydantoin racemase YP_004280218.1 AraC-type transcriptional regulator, N-terminal; AraC-type DNA-binding domain-containing proteins YP_004280219.1 Short-chain dehydrogenases of various substrate specificities YP_004280220.1 Bacterial regulatory proteins, tetR family; transcriptional regulator YP_004280222.1 CytB-hydogenase: Ni/Fe-hydrogenase, b-type cytochrome subunit; thiosulfate reductase cytochrome subunit beta (membrane anchoring protein) YP_004280223.1 oxidoreductase molybdopterin binding domain; Sulfite oxidase and related enzymes YP_004280227.1 CM_mono_cladeE: chorismate mutase; chorismate mutase YP_004280228.1 LysR substrate binding domain; transcriptional regulator YP_004280229.1 Short-chain dehydrogenases of various substrate specificities YP_004280230.1 alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004280231.1 glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004280232.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004280233.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004280234.1 endoribonuclease L-PSP/chorismate mutase-like; translation initiation inhibitor, yjgF family YP_004280236.1 Plasmid stabilisation system protein; Plasmid stabilization system protein YP_004280237.1 Aldo/keto reductase family; Aldo/keto reductases, related to diketogulonate reductase YP_004280238.1 NmrA-like; Predicted nucleoside-diphosphate-sugar epimerases YP_004280240.1 beta-lactamase-type transpeptidase fold; beta-lactamase class C and other penicillin binding proteins YP_004280241.1 LysR substrate binding domain, dsdC: D-serine deaminase transcriptional activator; transcriptional regulator YP_004280244.1 Fic protein family; Uncharacterized conserved protein YP_004280245.1 protein of unknown function DUF1857 YP_004280246.1 NmrA-like family; Predicted nucleoside-diphosphate-sugar epimerases YP_004280247.1 LysR substrate binding domain; transcriptional regulator YP_004280248.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280249.1 Short-chain dehydrogenases of various substrate specificities YP_004280250.1 Predicted dienelactone hydrolase YP_004280253.1 alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004280255.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280257.1 protein of unknown function DUF1452; Predicted small integral membrane protein YP_004280258.1 Multimeric flavodoxin WrbA YP_004280262.1 GroES-like, alcohol dehydrogenase GroES-like domain; threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004280263.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280264.1 FOG: PAS/PAC domain YP_004280267.1 NADPH-dependent FMN reductase; Multimeric flavodoxin WrbA YP_004280268.1 Exopolysaccharide synthesis, ExoD; Uncharacterized ABC-type transporter, permeases YP_004280269.1 Uncharacterized membrane protein YP_004280273.1 Uncharacterized protein conserved in bacteria YP_004280274.1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase, Pyridine nucleotide-disulphide oxidoreductase; thioredoxin reductase YP_004280275.1 catalase YP_004280276.1 protein of unknown function DUF892; Uncharacterized protein conserved in bacteria YP_004280277.1 protein of unknown function DUF892; Uncharacterized protein conserved in bacteria YP_004280278.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280279.1 glycosyl hydrolase, family 13, subfamily, catalytic region, trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase; 1,4-alpha-glucan branching enzyme YP_004280280.1 1,4-alpha-glucan branching enzyme YP_004280281.1 Bacterial regulatory protein, arsR family (repressor of nodulation genes); Predicted transcriptional regulators YP_004280284.1 protein of unknown function DUF1470; Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding YP_004280285.1 protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004280288.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280289.1 alcohol dehydrogenase GroES-like domain, fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent; threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004280291.1 Predicted Ku, prokaryotic type, Ku70/Ku80 beta-barrel domain; Uncharacterized conserved protein YP_004280292.1 Predicted Ku, prokaryotic type, Ku70/Ku80 beta-barrel domain; Uncharacterized conserved protein YP_004280294.1 catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_004280298.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; the rhizobia and the high GC gram-positive bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the S. meliloti protein in this cluster is associated with a groES gene and is required for regulation of the early genes involved in nodular formation; chaperonin GroEL (HSP60 family) YP_004280299.1 chaperonin 10 Kd subunit; Co-chaperonin GroES (HSP10) YP_004280300.1 Usg-like family; Usg protein, subunit of phosphoribosylanthranilate isomerase YP_004280302.1 Hsp20/alpha crystallin family; Molecular chaperone (small heat shock protein) YP_004280303.1 protein of unknown function DUF982 YP_004280305.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280306.1 CheY-like; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280307.1 HWE histidine kinase, sensory_box: PAS domain S-box YP_004280309.1 signal transduction histidine kinase YP_004280310.1 CheY-like, Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280311.1 Helix-turn-helix type 3 YP_004280312.1 Uncharacterized protein conserved in bacteria YP_004280314.1 glyoxalase/bleomycin resistance protein/dioxygenase; Uncharacterized protein conserved in bacteria YP_004280316.1 peptidase family M20/M25/M40; metal-dependentamidase/aminoacylase/carboxypeptidase YP_004280317.1 protein of unknown function UPF0157; Uncharacterized conserved protein YP_004280318.1 peptidase S16, lon N-terminal; ATP-dependent Lon protease bacterial type YP_004280320.1 Short-chain dehydrogenase/reductase SDR YP_004280321.1 Periplasmic binding proteins and sugar binding domain of the LacI family, fruct_sucro_rep: D-fructose-responsive transcription factor; transcriptional regulators YP_004280322.1 dihydrodipicolinate synthetase family; dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004280323.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004280324.1 Fic protein family; Uncharacterized conserved protein YP_004280325.1 antidote_CC2985: addiction module antidote protein, CC2985 family YP_004280326.1 Plasmid stabilization system; Plasmid stabilization system protein YP_004280327.1 methyl-accepting chemotaxis protein YP_004280329.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; transcriptional regulator YP_004280331.1 Homeodomain-like; transcriptional regulator YP_004280333.1 alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004280334.1 FOG: ankyrin repeat YP_004280335.1 NmrA-like; Predicted nucleoside-diphosphate-sugar epimerases YP_004280336.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280339.1 PilT protein, N-terminal; Predicted nucleic acid-binding protein, contains PIN domain YP_004280343.1 D-alanine-D-alanine ligase, C-terminal; D-alanine-D-alanine ligase and related ATP- grasp enzymes YP_004280344.1 Bacterial transglutaminase-like N-terminal region; transglutaminase-like enzymes, cysteine proteases YP_004280345.1 Integrase, catalytic core; transposase and inactivated derivatives YP_004280347.1 protein of unknown function DUF1814 YP_004280348.1 Predicted transcriptional regulator YP_004280351.1 Integrase, catalytic core; transposase and inactivated derivatives YP_004280352.1 protein of unknown function DUF1062; Uncharacterized protein conserved in bacteria YP_004280353.1 ThiJ/PfpI; intracellular protease/amidase YP_004280354.1 Bacterial regulatory proteins, luxR family; DNA-binding HTH domain-containing proteins YP_004280355.1 GGDEF: diguanylate cyclase (GGDEF) domain; FOG: GGDEF domain YP_004280357.1 EAL domain; c-di-GMP phosphodiesterase class I (EAL domain) YP_004280359.1 Bacterial regulatory proteins, gntR family; transcriptional regulators containing a DNA- binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs YP_004280361.1 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase, carbon-nitrogen hydrolase; Predicted amidohydrolase YP_004280362.1 Elongator protein 3/MiaB/NifB, radical SAM superfamily; Biotin synthase-related enzyme YP_004280364.1 Uncharacterised conserved protein UCP036540, AIR synthase related protein, C-terminal domain; Selenophosphate synthetase-related proteins YP_004280366.1 FAD dependent oxidoreductase; Predicted flavoprotein involved in K+ transport YP_004280368.1 methyl-accepting chemotaxis protein (MCP) signaling domain YP_004280370.1 Uncharacterised conserved protein UCP022704, protein of unknown function (DUF1349); Uncharacterized conserved protein YP_004280371.1 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280372.1 protein of unknown function DUF159; Uncharacterized conserved protein YP_004280373.1 ATP dependent DNA ligase domain, NHEJ_ligase_lig: DNA polymerase LigD, ligase domain YP_004280374.1 Uncharacterized conserved protein YP_004280375.1 nucleotidyltransferase/DNA polymerase involved in DNA repair YP_004280376.1 Bacterial DNA polymerase III subunit alpha; DNA polymerase III, subunit alpha YP_004280377.1 protein of unknown function DUF1419 YP_004280380.1 Region of unknown function DUF1738 YP_004280381.1 DNA breaking-rejoining enzyme, catalytic core, Phage integrase, N-terminal SAM-like domain; Site-specific recombinase XerD YP_004280382.1 ATP-binding region, ATPase-like YP_004280383.1 DNA breaking-rejoining enzyme, catalytic core YP_004280384.1 Region of unknown function DUF1738; antirestriction protein YP_004280385.1 protein of unknown function UPF0157; Uncharacterized conserved protein YP_004280387.1 protein of unknown function DUF736; Uncharacterized conserved protein YP_004280389.1 DNA breaking-rejoining enzyme, catalytic core, Phage integrase, N-terminal SAM-like domain; Site-specific recombinase XerD YP_004280391.1 Integrase, catalytic core, phage YP_004280395.1 Helix-turn-helix, HxlR type; Predicted transcriptional regulators YP_004280396.1 NmrA-like YP_004280398.1 IHF-like DNA-binding, Bacterial DNA-binding protein; Bacterial nucleoid DNA-binding protein YP_004280399.1 WGR domain; Uncharacterized conserved protein YP_004280402.1 Ti-type conjugative transfer system, TraG, TraG/TraD family; type IV secretory pathway, VirD4 components YP_004280403.1 Conjugal transfer TraD YP_004280404.1 TraC-like protein YP_004280405.1 Ti-type conjugative transfer relaxase TraA, MobA/MobL family; ATP-dependent exoDNAse (exonuclease V), subunit alpha - helicase superfamily I member YP_004280406.1 HipA-like, N-terminal & C-terminal domain; Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily YP_004280407.1 Lambda repressor-like, DNA-binding YP_004280408.1 acetyltransferase (GNAT) family; acetyltransferases YP_004280409.1 DNA breaking-rejoining enzyme, catalytic core; Site-specific recombinase XerD YP_004280410.1 DNA breaking-rejoining enzyme, catalytic core YP_004280412.1 required for attachment to host cells and virulence; acetyltransferases, including N-acetylases of ribosomal proteins YP_004280415.1 acetyltransferases YP_004280416.1 acetyltransferases YP_004280417.1 peptidase S9, serine active site; Hydrolases of the alpha/beta superfamily YP_004280418.1 peptidase family S41; Periplasmic protease YP_004280419.1 DNA breaking-rejoining enzyme, catalytic core; XerC, Site-specific recombinase XerC YP_004280421.1 ABC transporter ATP-binding protein-related protein; ATPase components of ABC transporters with duplicated ATPase domains YP_004280422.1 acetyltransferase (GNAT) family; acetyltransferases YP_004280423.1 DNA breaking-rejoining enzyme, catalytic core; Site-specific recombinase XerD YP_004280426.1 HEPN; Predicted nucleotidyltransferases YP_004280427.1 pyridoxal phosphate-dependent transferase, major region; 7-keto-8-aminopelargonate synthetase and related enzymes YP_004280428.1 transcriptional regulatory protein, C terminal, PhoB: phosphate regulon transcriptional regulatory protein CheY-like; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280429.1 Winged helix repressor DNA-binding; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280430.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280431.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; catalytic; thiamine pyrophosphate-requiring enzymes YP_004280432.1 pyridoxal phosphate-dependent transferase, major region, Aminotransferase class-III, hemL: glutamate-1-semialdehyde-2,1-aminomutase YP_004280433.1 GntR, C-terminal; transcriptional regulators YP_004280434.1 ABC transporter; ABC-type sugar transport systems, ATPase components YP_004280435.1 Binding-protein-dependent transporters inner membrane component; ABC-type spermidine/putrescine transporter, permease component I YP_004280436.1 Binding-protein-dependent transporter inner membrane component; ABC-type spermidine/putrescine transporter, permease component II YP_004280437.1 Bacterial extracellular solute-binding protein; Spermidine/putrescine-binding periplasmic protein YP_004280439.1 ABC transporter; ABC-type antimicrobial peptide transporter, ATPase component YP_004280440.1 protein of unknown function DUF214, permase , Predicted permease; ABC-type antimicrobial peptide transporter, permease component YP_004280441.1 proteins of unknown function (DUF2006); Predicted secreted hydrolase YP_004280443.1 transcriptional regulator IclR, C-terminal; transcriptional regulator YP_004280444.1 aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004280445.1 Iron-containing alcohol dehydrogenase; alcohol dehydrogenase, class IV YP_004280446.1 metallo-beta-lactamase superfamily; Zn-dependent hydrolases, including glyoxylases YP_004280448.1 Short-chain dehydrogenase/reductase SDR; Short-chain alcohol dehydrogenase of unknown specificity YP_004280449.1 GntR, C-terminal, FCD domain; transcriptional regulators YP_004280450.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004280451.1 Binding-protein-dependent transporter inner membrane component, ectoine_ehuC: ectoine/hydroxyectoine ABC transporter permease protein EhuC; ABC-type amino acid transporter, permease YP_004280452.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004280453.1 ABC transporter; ABC-type sugar transport systems, ATPase components YP_004280454.1 Bacterial extracellular solute-binding protein; Spermidine/putrescine-binding periplasmic protein YP_004280455.1 Binding-protein-dependent transporters inner membrane component; ABC-type spermidine/putrescine transporter, permease component I YP_004280456.1 Binding-protein-dependent transporters inner membrane component; ABC-type spermidine/putrescine transporter, permease component II YP_004280457.1 peptidase M24, catalytic core; Xaa-Pro aminopeptidase YP_004280458.1 FMN-binding split barrel; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004280459.1 OsmC-like protein; organic hydroperoxide reductase YP_004280460.1 Bacterial regulatory protein, MarR; transcriptional regulators YP_004280461.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280467.1 protein required for attachment to host cells YP_004280470.1 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) YP_004280471.1 VIRB2 type IV secretion, TrbC/VIRB2 family; type IV secretory pathway, VirB2 components (pilins) YP_004280472.1 type IV secretory pathway, VirB3-like protein; type IV secretory pathway, VirB3 components YP_004280473.1 CagE, TrbE, VirB family, component of type IV transporter system; type IV secretory pathway, VirB4 components YP_004280474.1 VirB5: P-type DNA transfer protein VirB5 YP_004280476.1 TrbL/VirB6 plasmid conjugal transfer protein; type IV secretory pathway, VirB6 components YP_004280477.1 type IV secretion system protein VirB7 YP_004280478.1 VirB8 protein; type IV secretory pathway, component VirB8 YP_004280479.1 P-type conjugative transfer protein VirB9, Conjugal transfer protein; type IV secretory pathway, VirB9 components YP_004280480.1 Bacterial conjugation TrbI-like protein; type IV secretory pathway, VirB10 components YP_004280481.1 type II/IV secretion system protein, VirB11: P-type DNA transfer ATPase VirB11; type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis YP_004280482.1 Winged helix repressor DNA-binding, Bacterial regulatory protein, arsR family; Predicted transcriptional regulators YP_004280483.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280484.1 transcription elongation factor, GreA/GreB region, prokaryotic; transcription elongation factor YP_004280486.1 transcription elongation factor, GreA/GreB region, prokaryotic; transcription elongation factor YP_004280487.1 protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004280488.1 glutamate/Leucine/phenylalanine/Valinedehydrogenase ; glutamate dehydrogenase/leucine dehydrogenase YP_004280491.1 NUDIX YP_004280494.1 histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacteriophytochrome (light-regulated signal transduction histidine kinase) YP_004280495.1 ATP-binding region, ATPase-like, HWE histidine kinase; Signal transduction histidine kinase YP_004280497.1 heat shock protein DnaJ, N-terminal; DnaJ-class molecular chaperone YP_004280499.1 Ribbon-helix-helix; Plasmid stability protein YP_004280500.1 PilT protein, N-terminal, PIN domain; Predicted nucleic acid-binding protein, contains PIN domain YP_004280501.1 dihydrodipicolinate synthetase family; dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004280502.1 Six-bladed beta-propeller, TolB-like, SMP-30/gluconolaconase/LRE-like region; gluconolactonase YP_004280503.1 GntR, C-terminal, FCD domain; transcriptional regulators YP_004280504.1 Bacterial extracellular solute-binding protein, family 5, nickel_nikA: nickel ABC transporter periplasmic nickel-binding protein; ABC-type dipeptide transporter, periplasmic component YP_004280505.1 Binding-protein-dependent transporter inner membrane component, nickel_nikB: nickel ABC transporter permease subunit NikB; ABC-type dipeptide/oligopeptide/nickel transporters, permease components YP_004280506.1 Binding-protein-dependent transporter inner membrane component, nickel_nikC: nickel ABC transporter permease subunit NikC; ABC-type dipeptide/oligopeptide/nickel transporters, permease components YP_004280507.1 ABC transporter nickel_nikD: nickel import ATP-binding protein NikD; ATPase components of various ABC-type transporters, contain duplicated ATPase YP_004280508.1 mandelate racemase / muconate lactonizing enzyme, N-terminal domain; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004280509.1 glycoside hydrolase-type carbohydrate-binding; Galactose mutarotase and related enzymes YP_004280510.1 GCN5-related N-acetyltransferase; acetyltransferases YP_004280511.1 oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004280512.1 ROK; transcriptional regulator/sugar kinase YP_004280513.1 Bacterial extracellular solute-binding protein, family 1; ABC-type Fe3+ transporter, periplasmic component YP_004280514.1 Binding-protein-dependent transporters inner membrane component; ABC-type Fe3+ transporter, permease YP_004280515.1 ABC transporter potA: polyamine ABC transporter ATP-binding protein; ABC-type sugar transporters, ATPase components YP_004280516.1 myo-inositol-1(or 4)-monophosphatase; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004280517.1 protein of unknown function UPF0118, Domain of unknown function DUF20; Predicted permease, member of the PurR regulon YP_004280519.1 Homeodomain-like YP_004280520.1 esterase, SGNH hydrolase-type; lysophospholipase L1 and related esterases YP_004280521.1 2-keto-3-deoxy-galactonokinase YP_004280522.1 dihydrodipicolinate synthetase; dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004280523.1 mandelate racemase / muconate lactonizing enzyme, N-terminal domain; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004280524.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transporter, periplasmic component YP_004280525.1 Binding-protein-dependent transporters inner membrane component; ABC-type sugar transporters, permeases YP_004280526.1 Binding-protein-dependent transporters inner membrane component; ABC-type sugar transporter, permease YP_004280527.1 ABC transporter; ABC-type sugar transporters, ATPase components YP_004280528.1 NAD dependent epimerase/dehydratase family; nucleoside-diphosphate-sugar epimerases YP_004280529.1 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; gluconolactonase YP_004280530.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280531.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_004280532.1 Cupin, RmlC-type; AraC-type DNA-binding domain-containing proteins YP_004280535.1 LysR substrate binding domain; transcriptional regulator YP_004280536.1 Aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004280537.1 LysR family transcriptional regulator YP_004280538.1 Winged helix repressor DNA-binding YP_004280539.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280540.1 alcohol dehydrogenase superfamily, zinc-containing; NADPH:quinone reductase and related Zn- dependent oxidoreductases YP_004280541.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280542.1 Short-chain alcohol dehydrogenase of unknown specificity YP_004280547.1 Biotin/lipoyl attachment; Multidrug resistance efflux pump YP_004280548.1 ABC transporter; ABC-type sugar transporters, ATPase components YP_004280549.1 protein of unknown function DUF214, permase ; ABC-type antimicrobial peptide transporter, permease YP_004280550.1 outer_NodT: efflux transporter outer membrane factor (OMF) lipoprotein, NodT family; Outer membrane protein YP_004280551.1 protein of unknown function DUF6, transmembrane YP_004280552.1 Uncharacterized protein conserved in bacteria YP_004280553.1 esterase/lipase YP_004280554.1 protein of unknown function DUF6, transmembrane YP_004280555.1 arginase/agmatinase/formimionoglutamate hydrolase, arginase family YP_004280556.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase and related aminotransferases YP_004280557.1 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling YP_004280560.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280561.1 histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004280562.1 Bacterial SH3-like region; Uncharacterized protein with a bacterial SH3 domain homologue YP_004280563.1 Secretion protein HlyD, RND_mfp: efflux transporter RND family, MFP subunit; Multidrug resistance efflux pump YP_004280564.1 ABC transporter; ABC-type antimicrobial peptide transport system, permease YP_004280566.1 cytochrome B561, bacterial YP_004280567.1 Tetracenomycin C & viologen resistance; Permeases of the major facilitator superfamily YP_004280568.1 CheY-like; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004280570.1 HlyD family secretion protein, RND_mfp: efflux transporter RND family, MFP subunit; membrane-fusion protein YP_004280571.1 Hydrophobe/amphiphile efflux-1 HAE1, AcrB/AcrD/AcrF family; Cation/multidrug efflux pump YP_004280573.1 ATPase (AAA+ superfamily protein); Predicted ATPase (AAA+ superfamily) YP_004280574.1 ABC transporter; ABC-type cobalamin/Fe3+-siderophores transporters, ATPase components YP_004280575.1 Bacterial transporter permease, FecCD transport family; ABC-type Fe3+-siderophore transporter, permease component YP_004280576.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transporter, periplasmic component YP_004280577.1 Bacterial regulatory protein, LacI; transcriptional regulators YP_004280578.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004280579.1 oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004280580.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004280581.1 Uncharacterized protein conserved in bacteria YP_004280582.1 gamma-glutamyltransferase YP_004280585.1 Multidrug resistance efflux pump YP_004280586.1 beta 1,3 glucan synthase catalytic subunit; glycosyltransferases, probably involved in cell wall biogenesis YP_004280587.1 Six-hairpin glycosidase-like YP_004280589.1 protein of unknown function DUF1852 YP_004280590.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; methionine synthase II (cobalamin-independent) YP_004280592.1 thioredoxin-like fold, Redoxin; peroxiredoxin YP_004280593.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280594.1 sugar-binding region; transcriptional regulator, contains sigma factor-related N-terminal domain YP_004280595.1 FGGY family of carbohydrate kinases, N-terminal domain, glycerol_kin: glycerol kinase; glycerol kinase YP_004280596.1 transketolase, central region YP_004280597.1 transketolase, thiamine diphosphate binding domain; transketolase YP_004280598.1 Bacterial inner-membrane translocator, Branched-chain amino acid transporter / permease; ribose/xylose/arabinose/galactoside ABC-type transporters, permease components YP_004280599.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transporter, periplasmic component YP_004280600.1 ABC transporter; ABC-type sugar transporter, ATPase component YP_004280601.1 Short-chain dehydrogenase/reductase SDR; dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004280604.1 histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004280605.1 circadian clock protein KaiC; RecA-superfamily ATPases implicated in signal transduction YP_004280606.1 Pirin; Pirin-related protein YP_004280607.1 Isochorismatase family; amidases related to nicotinamidase YP_004280608.1 LysR substrate binding domain; transcriptional regulator YP_004280609.1 HxlR-like helix-turn-helix; Predicted transcriptional regulators YP_004280610.1 alcohol dehydrogenase superfamily, zinc-containing; NADPH:quinone reductase and related Zn- dependent oxidoreductases YP_004280611.1 LysR substrate binding domain; transcriptional regulator YP_004280613.1 protein of unknown function DUF1348; Uncharacterized protein conserved in bacteria YP_004280614.1 carboxymuconolactone decarboxylase family; Uncharacterized conserved protein YP_004280615.1 pyridoxamine 5'-phosphate oxidase-related FMN-binding; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 YP_004280616.1 glutathione S-transferase, C-terminal-like & N-terminal domain; glutathione S-transferase YP_004280617.1 aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004280618.1 LysR, substrate-binding; transcriptional regulator YP_004280620.1 pyridoxamine 5'-phosphate oxidase-related, FMN-binding core; Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase YP_004280623.1 Bacterial regulatory proteins, deoR family; transcriptional regulators of sugar metabolism YP_004280624.1 RhaS: rhamnose ABC transporter rhamnose-binding protein; ABC-type sugar transporter, periplasmic component YP_004280625.1 ABC transporter; ATPase components of various ABC-type transporters, contain duplicated ATPase YP_004280626.1 Branched-chain amino acid transporter / permease component; ribose/xylose/arabinose/galactoside ABC-type transporters, permeases YP_004280627.1 Branched-chain amino acid transporter / permease component; ribose/xylose/arabinose/galactoside ABC-type transporters, permeases YP_004280629.1 ribokinase, bacterial; Sugar kinases, ribokinase family YP_004280630.1 deoxyribose-phosphate aldolase, DeoC/LacD family aldolase; deoxyribose-phosphate aldolase YP_004280631.1 aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004280633.1 lysine exporter (LYSE/YGGA); threonine efflux protein YP_004280634.1 nitrilase/cyanide hydratase and apolipoprotein; Predicted amidohydrolase YP_004280635.1 ABC transporter; ABC-type sugar transport systems, ATPase components YP_004280636.1 ABC transporter; ABC-type sugar transport systems, ATPase components YP_004280637.1 Branched-chain amino acid transporter / permease component; ABC-type branched-chain amino acid transporter, permease component YP_004280638.1 Branched-chain amino acid transporter / permease component; Branched-chain amino acid ABC-type transporter, permease components YP_004280639.1 extracellular ligand-binding receptor; ABC-type branched-chain amino acid transporters, periplasmic component YP_004280640.1 Response regulator antiterminator, ANTAR domain; Response regulator with antiterminator output domain YP_004280641.1 ABC-type branched-chain amino acid transporters, periplasmic component YP_004280643.1 Multiple antibiotic resistance (MarC)-related proteins; Multiple antibiotic transporter YP_004280645.1 Mechanosensitive ion channel; Small-conductance mechanosensitive channel YP_004280646.1 alpha/beta hydrolase of unknown function (DUF900); Uncharacterized protein conserved in bacteria YP_004280648.1 Secretion protein HlyD; Multidrug resistance efflux pump YP_004280650.1 Predicted integral membrane protein YP_004280652.1 glutathione S-transferase domain YP_004280653.1 AraC-type transcriptional regulator, N-terminal; AraC-type DNA-binding domain-containing proteins YP_004280654.1 Limonene-1,2-epoxide hydrolase catalytic domain; Limonene-1,2-epoxide hydrolase YP_004280655.1 ethanolamine ammonia-lyase light chain; ethanolamine ammonia-lyase, small subunit YP_004280656.1 ethanolamine ammonia-lyase, large subunit YP_004280657.1 inositol monophosphatase family, his_9_proposed: histidinol-phosphate phosphatase, ; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004280658.1 protein kinase-like, Choline/ethanolamine kinase; thiamine kinase and related kinases YP_004280659.1 protein kinase-like; thiamine kinase and related kinases YP_004280660.1 amidase, hydantoinase/carbamoylase, peptidase family M20/M25/M40; acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases YP_004280661.1 Bacterial regulatory proteins, deoR family; transcriptional regulators of sugar metabolism YP_004280662.1 ABC transporter; ATPase components of various ABC-type transporters, contain duplicated ATPase YP_004280663.1 Binding-protein-dependent transporter inner membrane component; ABC-type dipeptide/oligopeptide/nickel transporters, permease components YP_004280664.1 Binding-protein-dependent transporters inner membrane component; ABC-type dipeptide/oligopeptide/nickel transporters, permeases YP_004280665.1 Bacterial extracellular solute-binding protein, family 5 YP_004280668.1 ABC transporter; ABC-type sugar transport systems, ATPase components YP_004280669.1 alcohol dehydrogenase superfamily, zinc-containing; threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004280670.1 Binding-protein-dependent transporters inner membrane component; ABC-type sugar transporter, permease YP_004280671.1 Binding-protein-dependent transporters inner membrane component; ABC-type sugar transporters, permeases YP_004280672.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transporter, periplasmic component YP_004280673.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280674.1 Siderophore transporter RhtX/FptX family YP_004280675.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004280676.1 TonB-dependent siderophore receptor; Outer membrane receptor proteins, mostly Fe transport YP_004280678.1 heat shock protein Hsp90; Molecular chaperone, HSP90 family YP_004280679.1 methyltransferase type 12; methylase involved in ubiquinone/menaquinone biosynthesis YP_004280680.1 phospholipid-binding protein, PBP family; phospholipid-binding protein YP_004280683.1 Integrase, catalytic core; transposase and inactivated derivatives YP_004280687.1 LysR substrate binding domain; transcriptional regulator YP_004280688.1 carboxymuconolactone decarboxylase family; Uncharacterized conserved protein YP_004280689.1 NAD-dependent epimerase/dehydratase; Predicted nucleoside-diphosphate-sugar epimerases YP_004280690.1 Cupin, RmlC-type; Uncharacterized conserved protein, contains double-stranded beta-helix domain YP_004280691.1 Mechanosensitive ion channel; Small-conductance mechanosensitive channel YP_004280692.1 rrf2_super: rrf2 family protein ( transcriptional regulator); Predicted transcriptional regulator YP_004280693.1 Outer membrane autotransporter barrel; type V secretory pathway, adhesin AidA YP_004280696.1 LysR substrate binding domain; transcriptional regulator YP_004280697.1 NmrA-like family; Predicted nucleoside-diphosphate-sugar epimerases YP_004280698.1 protein of unknown function DUF1857 YP_004280699.1 LysR family transcriptional regulator; transcriptional regulator YP_004280700.1 Aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004280702.1 glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004280707.1 Cold shock, CspA; Cold shock proteins YP_004280709.1 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase, Mur ligase middle domain; UDP-N-acetylmuramyl pentapeptide synthase YP_004280710.1 type I secretion membrane fusion protein, HlyD; Multidrug resistance efflux pump YP_004280711.1 ABC transporter transmembrane region, type 1; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain YP_004280714.1 type I secretion outer membrane protein, TolC, Outer membrane efflux protein; Outer membrane protein YP_004280715.1 lysine exporter (LYSE/YGGA); threonine efflux protein YP_004280716.1 FAD dependent oxidoreductase; glycine/D-amino acid oxidases (deaminating) YP_004280717.1 oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004280718.1 ABC transporter; ATPase components of various ABC-type transporters, contain duplicated ATPase YP_004280719.1 ionotropic glutamate receptor, Bacterial extracellular solute-binding proteins, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004280720.1 Periplasmic binding protein/LacI transcriptional regulator; transcriptional regulators YP_004442843.1 PilT protein, N-terminal; Predicted nucleic acid-binding protein, contains PIN domain YP_004442844.1 Prevent-host-death protein YP_004442846.1 Protein of unknown function DUF172 YP_004442847.1 Staphylococcus nuclease (SNase-like); Micrococcal nuclease (thermonuclease) homologs YP_004442849.1 Protein of unknown function DUF1814; Uncharacterized conserved protein YP_004442850.1 Predicted transcriptional regulator YP_004442852.1 Acetyltransferases YP_004442853.1 Integrase, catalytic core; Transposase and inactivated derivatives YP_004442854.1 IstB-like ATP-binding protein; DNA replication protein YP_004442857.1 HEPN; Predicted nucleotidyltransferases YP_004442858.1 Uncharacterised conserved protein UCP031854; Uncharacterized conserved protein YP_004442859.1 TraG/TraD family; Type IV secretory pathway, VirD4 components YP_004442861.1 HEPN; Predicted nucleotidyltransferases YP_004442862.1 Transposase IS116/IS110/IS902 family; Transposase and inactivated derivatives YP_004442864.1 Ti-type conjugative transfer relaxase TraA, MobA/MobL family; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member YP_004442865.1 MgtC/SapB transporter; Uncharacterized membrane protein YP_004442874.1 Uncharacterized conserved protein YP_004442878.1 Rhs element Vgr protein; Uncharacterized protein conserved in bacteria YP_004442881.1 Virulence factor for secretion apparatus, Protein of unknown function (DUF796); Type VI protein secretion system component Hcp (secreted cytotoxin) YP_004442882.1 ATPase family associated with various cellular activities (AAA); ATPases with chaperone activity, ATP-binding subunit YP_004442883.1 ImpA-related N-terminal; Predicted component of the type VI protein secretion system YP_004442884.1 Uncharacterised conserved protein UCP028301, Protein of unknown function (DUF770); Predicted component of the type VI protein secretion system YP_004442885.1 Protein of unknown function DUF877; Predicted component of the type VI protein secretion system YP_004442886.1 Protein of unknown function DUF877; Predicted component of the type VI protein secretion system YP_004442887.1 Predicted virulence protein, SciE type; Protein of avirulence locus involved in temperature-dependent protein secretion YP_004442888.1 Gene 25-like lysozyme; Predicted component of the type VI protein secretion system YP_004442889.1 Protein of unknown function DUF879, bacterial; Predicted component of the type VI protein secretion system YP_004442890.1 Protein of unknown function DUF1305; Predicted component of the type VI protein secretion system YP_004442891.1 Predicted component of the type VI protein secretion system, contains a FHA domain YP_004442892.1 Protein of unknown function DUF876, bacterial; Predicted component of the type VI protein secretion system YP_004442893.1 Outer membrane protein, OmpA/MotB, C-terminal; Type VI protein secretion system component VasF YP_004442894.1 ImcF-related; Type VI protein secretion system component VasK YP_004442895.1 Protein phosphatase 2C-related; Uncharacterized protein conserved in bacteria YP_004442896.1 Protein kinase-like YP_004442897.1 Polysaccharide biosynthesis/export protein; Periplasmic protein involved in polysaccharide export YP_004442899.1 Activator of Hsp90 ATPase homolog 1-like protein; Uncharacterized conserved protein YP_004442900.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004442901.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004442902.1 Pyridoxal phosphate-dependent transferase, major region; Adenosylmethionine-8-amino-7-oxononanoateaminotransferase YP_004442903.1 transcriptional regulator, GntR family; Transcriptional regulators containing a DNA- binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs YP_004442904.1 catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization YP_004442905.1 putative cyclodeaminase; Predicted ornithine cyclodeaminase, mu- crystallin homolog YP_004442906.1 Ectoine utilization protein EutD; Xaa-Pro aminopeptidase YP_004442907.1 Succinylglutamate desuccinylase / Aspartoacylase family; Predicted deacylase YP_004442908.1 Ectoine/hydroxyEctoine ABC transporter solute-binding protein, Bacterial extracellular solute-binding proteins, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004442909.1 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC, Binding-protein-dependent transport system inner membrane component; ABC-type amino acid transport system, permease component YP_004442910.1 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD, Binding-protein-dependent transport system inner membrane component; ABC-type amino acid transport system, permease component YP_004442911.1 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein; ABC-type polar amino acid transport system, ATPase component YP_004442912.1 transcriptional regulator-like protein; Predicted transcriptional regulator YP_004442914.1 Uncharacterised conserved protein UCP019307, cupin region; Uncharacterized protein containing double- stranded beta helix domain YP_004442915.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; Transcriptional regulator YP_004442916.1 short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004442917.1 Uncharacterized protein conserved in bacteria YP_004442918.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004442919.1 Quinoprotein amine dehydrogenase, beta chain-like YP_004442920.1 Fibronectin, type III-like fold; PPE-repeat proteins YP_004442921.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004442922.1 Lipocalin-like domain; Bacterial lipocalin YP_004442924.1 Curlin associated repeat YP_004442926.1 Curlin associated YP_004442928.1 Uncharacterized protein related to deoxyribodipyrimidine photolyase YP_004442929.1 GCN5-related N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004442931.1 EAL domain; FOG: EAL domain YP_004442933.1 Cyclopropane fatty acid synthase and related methyltransferases YP_004442934.1 Protein of unknown function DUF1295; Predicted membrane protein YP_004442935.1 Amine oxidase [flavin-containing]; Predicted NAD/FAD-binding protein YP_004442936.1 Protein of unknown function DUF1365; Uncharacterized conserved protein YP_004442937.1 Cyclopropane fatty acid synthase and related methyltransferases YP_004442938.1 Uncharacterized protein conserved in bacteria YP_004442939.1 Predicted membrane protein YP_004442940.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004442941.1 Uncharacterized protein conserved in bacteria YP_004442942.1 Protein of unknown function DUF72; Uncharacterized conserved protein YP_004442944.1 Cytochrome c, monohaem YP_004442945.1 Protein of unknown function DUF892 YP_004442947.1 Transglutaminase-like superfamily; Transglutaminase-like enzymes, putative cysteine proteases YP_004442948.1 EAL domain; Predicted signal transduction protein containing sensor and EAL domains YP_004442949.1 Activator of Hsp90 ATPase homolog 1-like protein; Uncharacterized conserved protein YP_004442950.1 Bacterial regulatory protein, arsR family; Predicted transcriptional regulators YP_004442951.1 ABC transporter, transmembrane region, type 1; ABC-type multidrug transport system, ATPase and permease components YP_004442952.1 Bordetella uptake gene (bug) product; Uncharacterized protein conserved in bacteria YP_004442953.1 Bacterial regulatory proteins, luxR family; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_004442954.1 CsbD-like YP_004442956.1 Protein of unknown function DUF992 YP_004442958.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004442959.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004442960.1 Acetyltransferases YP_004442961.1 Major facilitator superfamily YP_004442963.1 Formate dehydrogenase, alpha subunit; Uncharacterized anaerobic dehydrogenase YP_004442964.1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit YP_004442965.1 NADH dehydrogenase (ubiquinone), 24 kDa subunit; NADH:ubiquinone oxidoreductase 24 kD subunit YP_004442966.1 LysR substrate binding domain; Transcriptional regulator YP_004442967.1 Asp/Glu/Hydantoin racemase YP_004442968.1 FMN-binding split barrel, related; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004442969.1 GntR, C-terminal; Transcriptional regulators YP_004442970.1 ABC transporter related; ABC-type oligopeptide transport system, ATPase component YP_004442971.1 ABC transporter related; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004442972.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; Cytosine deaminase and related metal-dependent hydrolases YP_004442973.1 Catalyzes the deamination of cytosine to uracil and ammonia; Cytosine deaminase and related metal-dependent hydrolases YP_004442974.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004442975.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004442976.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004442977.1 Amidohydrolase family; Cytosine deaminase and related metal-dependent hydrolases YP_004442978.1 Porin, alpha proteobacteria type YP_004442979.1 diguanylate cyclase (GGDEF) domain; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain YP_004442980.1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Lactate dehydrogenase and related dehydrogenases YP_004442981.1 ABC transporter, nucleotide binding/ATPase protein (amino acid); ABC-type polar amino acid transport system, ATPase component YP_004442982.1 Binding-protein-dependent transport system inner membrane component; ABC-type amino acid transport system, permease component YP_004442983.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004442984.1 Bacterial extracellular solute-binding proteins, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004442986.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004442987.1 Proline racemase YP_004442988.1 Protein of unknown function (DUF521); Uncharacterized conserved protein YP_004442989.1 FAD dependent oxidoreductase; Glycine/D-amino acid oxidases (deaminating) YP_004442990.1 ABC transporter, nucleotide binding/ATPase protein (amino acid); ABC-type polar amino acid transport system, ATPase component YP_004442991.1 Binding-protein-dependent transport system inner membrane component; ABC-type amino acid transport system, permease component YP_004442992.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004442993.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004442995.1 Malate/L-lactate dehydrogenase; Malate/L-lactate dehydrogenases YP_004442996.1 Dihydrodipicolinate synthetase family; Dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004442997.1 GntR, C-terminal; Transcriptional regulators YP_004442998.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; Cell division GTPase YP_004442999.1 LovR from Caulobacter crescentus is a response regulator part of a two-component signaling system that regulates photosensitive bacterial cell-surface and cell-cell attachment; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443000.1 Protein of unknown function DUF1127 YP_004443002.1 Glycoside hydrolase, family 4; Alpha-galactosidases/6-phospho-beta- glucosidases, family 4 of glycosyl hydrolases YP_004443003.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type uncharacterized transport system, duplicated ATPase component YP_004443004.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443005.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443006.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443007.1 Glycoside hydrolase, family 4; Alpha-galactosidases/6-phospho-beta- glucosidases, family 4 of glycosyl hydrolases YP_004443008.1 AraC protein, arabinose-binding/dimerisation; AraC-type DNA-binding domain-containing proteins YP_004443010.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004443011.1 N- acetylglucosaminylphosphatidylinositoldeacetylase; Uncharacterized proteins, LmbE homologs YP_004443012.1 ROK family; Transcriptional regulator/sugar kinase YP_004443013.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443014.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443015.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443017.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004443018.1 Carbohydrate/purine kinase; Sugar kinases, ribokinase family YP_004443019.1 Arylsulfatase A and related enzymes YP_004443020.1 ABC-type proline/glycine betaine transport systems, periplasmic components YP_004443021.1 LysR, substrate-binding; Transcriptional regulator YP_004443022.1 Aldehyde dehydrogenase; NAD-dependent aldehyde dehydrogenases YP_004443024.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004443025.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443026.1 putative transmembrane protein YP_004443027.1 Helix-turn-helix, HxlR type; Predicted transcriptional regulators YP_004443028.1 putative ABC transporter, possibly in operon (iron uptake); ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components YP_004443029.1 ABC-type enterobactin transport system, permease component YP_004443030.1 ABC-type Fe3+-siderophore transport system, permease component YP_004443031.1 ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004443032.1 Outer membrane receptor for monomeric catechols YP_004443033.1 similarity to AraC family transcriptional regulators; AraC-type DNA-binding domain-containing proteins YP_004443035.1 Catalase-peroxidase haem; Catalase (peroxidase I) YP_004443036.1 LysR substrate binding domain; Transcriptional regulator YP_004443037.1 Uncharacterized protein conserved in bacteria YP_004443038.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004443039.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443040.1 Secretion protein HlyD; Membrane-fusion protein YP_004443041.1 Cation/multidrug efflux pump YP_004443042.1 NUDIX; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004443043.1 Protein of unknown function DUF47; Phosphate transport regulator (distant homolog of PhoU) YP_004443044.1 Phosphate transporter family (N-terminal); Phosphate/sulphate permeases YP_004443045.1 Predicted Ku, prokaryotic type; Ku-homolog YP_004443046.1 DNA ligase D YP_004443047.1 Predicted Ku, prokaryotic type; Uncharacterized conserved protein YP_004443049.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443050.1 diguanylate cyclase (GGDEF) domain; c-di-GMP phosphodiesterase class I (EAL domain) YP_004443052.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443053.1 D-mannonate dehydratase YP_004443054.1 GntR, C-terminal; Transcriptional regulators YP_004443055.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443056.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443057.1 ABC transporter, nucleotide binding/ATPase protein (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004443058.1 ABC transporter related; ABC-type oligopeptide transport system, ATPase component YP_004443059.1 ABC transporter, nucleotide binding/ATPase protein (sugars); ABC-type sugar transport systems, ATPase components YP_004443060.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443061.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443062.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443064.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004443065.1 Predicted peptidase YP_004443066.1 DNA helicase, UvrD/REP type; Superfamily I DNA and RNA helicases YP_004443067.1 DNA-damage-inducible protein; Nucleotidyltransferase/DNA polymerase involved in DNA repair YP_004443068.1 TonB-dependent siderophore receptor, ferrichrome-iron transporter; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid YP_004443069.1 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components YP_004443070.1 Bacterial transport system permease protein; ABC-type Fe3+-siderophore transport system, permease component YP_004443071.1 Bacterial transport system permease protein; ABC-type Fe3+-siderophore transport system, permease component YP_004443072.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004443073.1 Sugar isomerase (SIS); Transcriptional regulators YP_004443074.1 dTDP-4-dehydrorhamnose 3,5-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes YP_004443075.1 NAD dependent epimerase/dehydratase family; dTDP-D-glucose 4,6-dehydratase YP_004443077.1 Glucose-1-phosphate thymidylyltransferase, long form; dTDP-glucose pyrophosphorylase YP_004443078.1 Glycosyl transferase, family 2; Predicted glycosyltransferases YP_004443079.1 NAD dependent epimerase/dehydratase family; Nucleoside-diphosphate-sugar epimerases YP_004443080.1 Glycosyl transferase, family 2 YP_004443081.1 Methylase involved in ubiquinone/menaquinone biosynthesis YP_004443082.1 Predicted membrane protein YP_004443083.1 Amine oxidase; Protoporphyrinogen oxidase YP_004443084.1 NAD dependent epimerase/dehydratase family; Predicted nucleoside-diphosphate-sugar epimerases YP_004443085.1 Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenases of various substrate specificities YP_004443086.1 FAD linked oxidase, N-terminal; FAD/FMN-containing dehydrogenases YP_004443087.1 UbiA prenyltransferase family; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases YP_004443090.1 Methylase involved in ubiquinone/menaquinone biosynthesis YP_004443094.1 Transketolase, thiamine diphosphate binding domain; Transketolase YP_004443095.1 Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II; Transketolase, C-terminal subunit YP_004443096.1 NAD dependent epimerase/dehydratase family; Nucleoside-diphosphate-sugar epimerases YP_004443098.1 Transposase IS116/IS110/IS902 family; Transposase and inactivated derivatives YP_004443099.1 Integrase, catalytic core; Transposase and inactivated derivatives YP_004443100.1 Integrase, catalytic core; Transposase and inactivated derivatives YP_004443101.1 lipid A export permease/ATP-binding protein MsbA; ABC-type multidrug transport system, ATPase and permease components YP_004443102.1 Transcriptional regulator IclR, C-terminal; Transcriptional regulator YP_004443103.1 ABC transporter related; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004443104.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004443105.1 NMT1/THI5 like; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004443106.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443108.1 Fumarylacetoacetate (FAA) hydrolase family; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene- 1,7-dioic acid hydratase (catechol pathway) YP_004443109.1 Fumarylacetoacetase, C-terminal-related; 2-keto-4-pentenoate hydratase YP_004443110.1 Sodium Bile acid symporter family; Predicted Na+-dependent transporter YP_004443111.1 HEPN; Predicted nucleotidyltransferases YP_004443112.1 Transposase IS116/IS110/IS902 family; Transposase and inactivated derivatives YP_004443114.1 Ti-type conjugative transfer relaxase TraA; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member YP_004443116.1 Acetyltransferases, including N-acetylases of ribosomal proteins YP_004443118.1 Esterase, SGNH hydrolase-type YP_004443121.1 Toll-Interleukin receptor YP_004443122.1 putative DNA binding; Predicted transcriptional regulator YP_004443124.1 Helicase, superfamily 1, UvrD-related; ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) YP_004443125.1 AAA+ ATPase, core; GTPase subunit of restriction endonuclease YP_004443126.1 hypothetical protein; McrBC 5-methylcytosine restriction system component YP_004443127.1 a part of a conjugal transfer protein TraA YP_004443128.1 Restriction endonuclease, type I, R subunit/Type III, Res subunit YP_004443129.1 DNA methylase N-4/N-6; Adenine specific DNA methylase Mod YP_004443131.1 Integrase, Lamba-type, N-terminal; Site-specific recombinase XerD YP_004443132.1 DNA breaking-rejoining enzyme, catalytic core; Integrase YP_004443134.1 Major facilitator superfamily; Arabinose efflux permease YP_004443139.1 Cytochrome c biogenesis protein, transmembrane region; Cytochrome c biogenesis protein YP_004443140.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004443141.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004443142.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443143.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004443145.1 type I secretion membrane fusion protein, HlyD family; Membrane-fusion protein YP_004443146.1 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain YP_004443149.1 Polynucleotidyl transferase, Ribonuclease H fold; Transposase and inactivated derivatives YP_004443150.1 PilT protein, N-terminal; Predicted nucleic acid-binding protein, contains PIN domain YP_004443152.1 OsmC-like protein; Predicted redox protein, regulator of disulfide bond formation YP_004443154.1 putative cyclase; Kynurenine formamidase YP_004443155.1 TRAP C4-dicarboxylate transport system permease DctM subunit; TRAP-type C4-dicarboxylate transport system, large permease component YP_004443156.1 TRAP dicarboxylate transporter-DctP subunit; TRAP-type C4-dicarboxylate transport system, periplasmic component YP_004443157.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443158.1 transcriptional regulator, IclR family; Transcriptional regulator YP_004443159.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Acetyl-CoA acetyltransferase YP_004443160.1 activates fatty acids by binding to coenzyme A; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_004443161.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443165.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004443166.1 Hydantoinase B/oxoprolinase; N-methylhydantoinase B/acetone carboxylase, alpha subunit YP_004443167.1 Hydantoinase/oxoprolinase; N-methylhydantoinase A/acetone carboxylase, beta subunit YP_004443168.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004443169.1 Transcriptional regulator IclR, N-terminal; Transcriptional regulator YP_004443170.1 conversion of mannopinic acid to glutamic acid and mannose; N-methylhydantoinase B/acetone carboxylase, alpha subunit YP_004443171.1 conversion of mannopinic acid to glutamic acid and mannose; N-methylhydantoinase A/acetone carboxylase, beta subunit YP_004443172.1 transporter substrate binding protein; periplasmic, agropinic acid binding protein; ABC-type dipeptide transport system, periplasmic component YP_004443173.1 ABC transporter permease protein; agropinic acid inner-membrane protein; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443174.1 ABC transporter permease protein; agropinic acid inner-membrane protein; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443175.1 ATP-binding protein; agropinic acid ATP-binding protein; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004443176.1 conversion of agropinic acid to mannopinic acid; Glycine/D-amino acid oxidases (deaminating) YP_004443177.1 Fumarase YP_004443178.1 Glycine/D-amino acid oxidases (deaminating) YP_004443179.1 ABC-type polar amino acid transport system, ATPase component YP_004443180.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004443181.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004443182.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004443183.1 Transcriptional regulator IclR, C-terminal; Transcriptional regulator YP_004443184.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443185.1 FAD dependent oxidoreductase; Glycine/D-amino acid oxidases (deaminating) YP_004443186.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004443187.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004443188.1 Binding-protein-dependent transport systems inner membrane component; ABC-type polysaccharide transport system, permease component YP_004443189.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443190.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443191.1 Heparinase II/III-like protein YP_004443192.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443193.1 Esterase, SGNH hydrolase-type YP_004443194.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Phosphoglycerate dehydrogenase and related dehydrogenases YP_004443195.1 Sugar phosphate isomerases/epimerases YP_004443196.1 Mandelate racemase/muconate lactonizing enzyme; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004443197.1 Protein of unknown function DUF982 YP_004443198.1 Hsp20/alpha crystallin family; Molecular chaperone (small heat shock protein) YP_004443199.1 Glycosyl transferase, group 1 YP_004443200.1 Glycosyl transferases group 1 YP_004443201.1 Glycosyl transferase, group 1 YP_004443202.1 Trimeric LpxA-like; Acetyltransferase (isoleucine patch superfamily) YP_004443204.1 Uncharacterized conserved protein YP_004443205.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyl; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase YP_004443207.1 Glycosyl transferase, group 1 YP_004443208.1 Polysaccharide pyruvyl transferase; Uncharacterized conserved protein YP_004443209.1 Polysaccharide biosynthesis protein; Membrane protein involved in the export of O- antigen and teichoic acid YP_004443210.1 Glycosyl transferase, family 2; Glycosyltransferases involved in cell wall biogenesis YP_004443211.1 MCP methyltransferase, CheR-type; Methylase of chemotaxis methyl-accepting proteins YP_004443212.1 Bacterial regulatory proteins, luxR family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443213.1 catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Glutamate-1-semialdehyde aminotransferase YP_004443214.1 NAD-dependent epimerase/dehydratase; dTDP-D-glucose 4,6-dehydratase YP_004443215.1 Uncharacterised conserved protein UCP01524, polysaccharide biosynthesis aminopeptidase-like; Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain YP_004443216.1 dTDP-4-dehydrorhamnose 3,5-epimerase; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes YP_004443217.1 SAM-dependent methyltransferases YP_004443218.1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF- 2Bgamma/eIF-2Bepsilon) YP_004443219.1 N- acetylglucosaminylphosphatidylinositoldeacetylase; Uncharacterized proteins, LmbE homologs YP_004443220.1 Bacterial regulatory proteins, luxR family; DNA-binding HTH domain-containing proteins YP_004443221.1 capsular exopolysaccharide family; Uncharacterized protein involved in exopolysaccharide biosynthesis YP_004443222.1 Polysaccharide biosynthesis/export protein; Periplasmic protein involved in polysaccharide export YP_004443224.1 Pectin lyase fold/virulence factor; Endopolygalacturonase YP_004443225.1 Nucleoside-diphosphate-sugar epimerases YP_004443226.1 NAD dependent epimerase/dehydratase family; GDP-D-mannose dehydratase YP_004443227.1 Methyltransferase type 12; Dimethyladenosine transferase (rRNA methylation) YP_004443228.1 LysR substrate binding domain; Transcriptional regulator YP_004443229.1 Twin-arginine translocation pathway signal; Hydrolases of the alpha/beta superfamily YP_004443230.1 Major facilitator superfamily; Arabinose efflux permease YP_004443231.1 Uncharacterized conserved protein YP_004443232.1 Protein of unknown function DUF1452; Predicted small integral membrane protein YP_004443233.1 ABC transporter, transmembrane region, type 1; ABC-type uncharacterized transport system, permease and ATPase components YP_004443234.1 diguanylate cyclase (GGDEF) domain; Response regulator containing a CheY-like receiver domain and a GGDEF domain YP_004443235.1 Transcriptional regulator/sugar kinase YP_004443236.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_004443237.1 in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Predicted 6-phosphogluconate dehydrogenase YP_004443238.1 Glucan 1,4-alpha-glucosidase; Glucoamylase and related glycosyl hydrolases YP_004443239.1 FGGY family of carbohydrate kinases, N-terminal domain YP_004443240.1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Thioredoxin reductase YP_004443241.1 Predicted dehydrogenase YP_004443242.1 Ethanolamine ammonia-lyase light chain; Ethanolamine ammonia-lyase, small subunit YP_004443243.1 Ethanolamine ammonia lyase large subunit; Ethanolamine ammonia-lyase, large subunit YP_004443244.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component II YP_004443245.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component I YP_004443246.1 ABC-type sugar transport systems, ATPase components YP_004443247.1 Bacterial extracellular solute-binding protein, family 1; Spermidine/putrescine-binding periplasmic protein YP_004443248.1 Demethylmenaquinone methyltransferase YP_004443249.1 Nitrilase/cyanide hydratase and apolipoprotein; Predicted amidohydrolase YP_004443250.1 LysR substrate binding domain; Transcriptional regulator YP_004443251.1 Cupin, RmlC-type YP_004443252.1 Glycine/D-amino acid oxidases (deaminating) YP_004443253.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443254.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443255.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443256.1 Glycine/D-amino acid oxidases (deaminating) YP_004443257.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443258.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004443259.1 ABC transporter, nucleotide binding/ATPase protein (peptide); ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004443261.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004443262.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Cystathionine beta-lyases/cystathionine gamma- synthases YP_004443263.1 Metal-dependent protein hydrolase; Uncharacterized conserved protein related to MYG1 family YP_004443264.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004443265.1 LysR substrate binding domain; Transcriptional regulator YP_004443266.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443269.1 LysR, substrate-binding; Transcriptional regulator YP_004443271.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443272.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443273.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443274.1 ABC-type uncharacterized transport system, duplicated ATPase component YP_004443275.1 CocE/NonD hydrolase; Predicted acyl esterases YP_004443276.1 Predicted nucleic acid-binding protein, contains PIN domain YP_004443277.1 Cold-shock protein, DNA-binding; Cold shock proteins YP_004443279.1 Histidine kinase; Signal transduction histidine kinase YP_004443280.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443281.1 Predicted periplasmic ligand-binding sensor domain YP_004443282.1 ABC transporter, nucleotide binding/ATPase protein; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004443283.1 Gamma-glutamyltransferase YP_004443284.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443285.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443286.1 Bacterial extracellular solute-binding proteins, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443287.1 GntR, C-terminal; Transcriptional regulators YP_004443288.1 Beta-lactamase-type transpeptidase fold; Beta-lactamase class C and other penicillin binding proteins YP_004443289.1 LysR, substrate-binding; Transcriptional regulator YP_004443290.1 Chromate transporter; Chromate transport protein ChrA YP_004443291.1 Protein of unknown function DUF1501; Uncharacterized protein conserved in bacteria YP_004443292.1 Protein of unknown function DUF1800; Uncharacterized protein conserved in bacteria YP_004443293.1 Predicted integral membrane protein YP_004443295.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004443296.1 Asp/Glu/Hydantoin racemase YP_004443297.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component II YP_004443298.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component I YP_004443299.1 Twin-arginine translocation pathway signal; Spermidine/putrescine-binding periplasmic protein YP_004443300.1 ABC transporter, nucleotide binding/ATPase protein (spermidine/putrescine); ABC-type spermidine/putrescine transport systems, ATPase components YP_004443302.1 ABC transporter, nucleotide binding/ATPase protein; ABC-type polar amino acid transport system, ATPase component YP_004443303.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004443304.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004443305.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004443306.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004443307.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases YP_004443308.1 Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; Predicted flavoprotein involved in K+ transport YP_004443309.1 Threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004443310.1 RNA polymerase sigma factor 54, interaction; Transcriptional activator of acetoin/glycerol metabolism YP_004443312.1 Lytic transglycosylase-like, catalytic; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) YP_004443313.1 Bacterial chemotaxis sensory transducer; Methyl-accepting chemotaxis protein YP_004443314.1 3-demethylubiquinone-9 3-O-methyltransferase; Uncharacterized protein conserved in bacteria YP_004443315.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443316.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443317.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443318.1 part of the UgpABCE glycerol-3-phosphate uptake system; ABC-type sugar transport systems, ATPase components YP_004443319.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443320.1 ABC transporter, substrate-binding protein, aliphatic sulphonates; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004443321.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004443322.1 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004443323.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443324.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443325.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443326.1 ABC transporter, nucleotide binding/ATPase protein (lactose); ABC-type sugar transport systems, ATPase components YP_004443327.1 Alpha-L-arabinofuranosidase C-terminus YP_004443328.1 Winged helix repressor DNA-binding; Predicted transcriptional regulator YP_004443329.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443330.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004443331.1 Uncharacterized protein conserved in bacteria YP_004443332.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Lactate dehydrogenase and related dehydrogenases YP_004443333.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004443334.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004443335.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443336.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443337.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443338.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004443339.1 Oxidoreductase, C-terminal; Predicted dehydrogenases and related proteins YP_004443340.1 Protein of unknown function DUF993 YP_004443341.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004443342.1 Oxidoreductase, C-terminal, Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004443345.1 Cold shock, CspA; Cold shock proteins YP_004443347.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; Ribosomal protein S21 YP_004443355.1 Acyltransferase 3; Predicted acyltransferases YP_004443356.1 Acyl carrier protein (ACP) YP_004443357.1 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein; ABC-type antimicrobial peptide transport system, permease component YP_004443358.1 Secretion protein HlyD; Membrane-fusion protein YP_004443361.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443362.1 Signal transduction histidine kinase YP_004443363.1 Six-hairpin glycosidase-like; Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins YP_004443364.1 Pectin lyase fold/virulence factor, Glycosyl hydrolases family 28; Endopolygalacturonase YP_004443365.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443366.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004443367.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443368.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443369.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004443370.1 TRAP C4-dicarboxylate transport system permease DctM subunit; TRAP-type C4-dicarboxylate transport system, large permease component YP_004443371.1 Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP-type C4-dicarboxylate transport system, small permease component YP_004443372.1 TRAP dicarboxylate transporter-DctP subunit; TRAP-type C4-dicarboxylate transport system, periplasmic component YP_004443373.1 Amidohydrolase 2; Predicted metal-dependent hydrolase of the TIM- barrel fold YP_004443374.1 Mandelate racemase/muconate lactonizing enzyme; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004443375.1 Dihydrodipicolinate synthetase family; Dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004443376.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443377.1 5-keto 4-deoxyuronate isomerase YP_004443378.1 NAD-dependent epimerase/dehydratase; Nucleoside-diphosphate-sugar epimerases YP_004443379.1 GntR, C-terminal; Transcriptional regulators YP_004443380.1 Cupin, RmlC-type; Uncharacterized conserved protein, contains double-stranded beta-helix domain YP_004443381.1 Peptidase M24, catalytic core; Xaa-Pro aminopeptidase YP_004443383.1 Aldo/keto reductase, Oxidoreductase family, NAD-binding Rossmann fold; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004443384.1 ABC transporter, nucleotide binding/ATPase protein (lactose); ABC-type sugar transport systems, ATPase components YP_004443385.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443386.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443387.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443388.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004443389.1 AraC protein, arabinose-binding/dimerisation; AraC-type DNA-binding domain-containing proteins YP_004443390.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004443391.1 LysR, substrate-binding; Transcriptional regulator YP_004443392.1 TRAP C4-dicarboxylate transport system permease DctM subunit; TRAP-type C4-dicarboxylate transport system, large permease component YP_004443393.1 Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP-type C4-dicarboxylate transport system, small permease component YP_004443394.1 TRAP-type C4-dicarboxylate transport system, periplasmic component YP_004443395.1 2-hydroxy-3-oxopropionate reductase; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_004443396.1 Antibiotic biosynthesis monooxygenase; Uncharacterized conserved protein YP_004443397.1 Oxidoreductase, N-terminal; Predicted homoserine dehydrogenase YP_004443398.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004443399.1 Alcohol dehydrogenase superfamily, zinc-containing; Threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004443400.1 Converts D-sorbitol to L-sorbose; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443401.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443402.1 Carbohydrate/purine kinase; Sugar kinases, ribokinase family YP_004443403.1 D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit AgaZ; Predicted tagatose 6-phosphate kinase YP_004443404.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443405.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443406.1 ABC transporter, nucleotide binding/ATPase protein (sorbitol/mannitol); ABC-type sugar transport systems, ATPase components YP_004443407.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004443408.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443409.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443410.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443411.1 Cys/Met metabolism PLP-dependent enzyme; Cystathionine beta-lyases/cystathionine gamma- synthases YP_004443412.1 GntR, C-terminal; Transcriptional regulators YP_004443413.1 Periplasmic solute binding protein family; ABC-type metal ion transport system, periplasmic component/surface adhesin YP_004443414.1 ABC 3 transport family; ABC-type Mn2+/Zn2+ transport systems, permease components YP_004443415.1 iron ABC transporter, ATP-binding protein; ABC-type Mn/Zn transport systems, ATPase component YP_004443416.1 Cobalamin (vitamin B12) biosynthesis CobW-like; Putative GTPases (G3E family) YP_004443417.1 Predicted membrane protein YP_004443419.1 Cobalamin (vitamin B12) biosynthesis CobW-like; Putative GTPases (G3E family) YP_004443420.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443421.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443422.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443423.1 ABC-type sugar transport systems, ATPase components YP_004443424.1 Acyltransferase 3; Predicted acyltransferases YP_004443426.1 Outer membrane protein, OmpW; Outer membrane protein W YP_004443427.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004443428.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004443429.1 Peptidase S9, serine active site; Hydrolases of the alpha/beta superfamily YP_004443431.1 Translation elongation factors (GTPases) YP_004443432.1 Ornithine cyclodeaminase/mu-crystallin family; Predicted ornithine cyclodeaminase, mu- crystallin homolog YP_004443433.1 ADP-ribose pyrophosphatase YP_004443434.1 Predicted kinase YP_004443435.1 Acetyltransferases, including N-acetylases of ribosomal proteins YP_004443437.1 Methyltransferase type 11; SAM-dependent methyltransferases YP_004443438.1 GCN5-related N-acetyltransferase; Acetyltransferases YP_004443439.1 Peptidase S9, prolyl oligopeptidase active site region; Dipeptidyl aminopeptidases/acylaminoacyl- peptidases YP_004443440.1 Bacterial protein of unknown function (DUF925); Uncharacterized protein conserved in bacteria YP_004443442.1 Aminoacyl-tRNA synthetase, class II (D, K and N); Aspartyl/asparaginyl-tRNA synthetases YP_004443446.1 Predicted beta-xylosidase YP_004443449.1 Homeodomain-like YP_004443450.1 Predicted acetyltransferase YP_004443451.1 Orn/DAP/Arg decarboxylase 2; Diaminopimelate decarboxylase YP_004443452.1 LysR, substrate-binding; Transcriptional regulator YP_004443453.1 ABC transporter, substrate binding protein (ribose); ABC-type sugar transport system, periplasmic component YP_004443454.1 Branched-chain amino acid transport system / permease component; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004443455.1 ABC transporter, nucleotide binding/ATPase protein (ribose); ABC-type sugar transport system, ATPase component YP_004443456.1 diguanylate cyclase (GGDEF) domain; c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) YP_004443457.1 Protein of unknown function (DUF861); Uncharacterized protein, possibly involved in glyoxylate utilization YP_004443458.1 Methyltransferase type 12 YP_004443459.1 diguanylate cyclase (GGDEF) domain; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain YP_004443460.1 Malate/L-lactate dehydrogenase; Malate/L-lactate dehydrogenases YP_004443461.1 putative ftsk cell division protein; DNA segregation ATPase FtsK/SpoIIIE and related proteins YP_004443462.1 Bacterial extracellular solute-binding proteins, family 5 Middle; ABC-type dipeptide transport system, periplasmic component YP_004443463.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443464.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443465.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004443466.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type oligopeptide transport system, ATPase component YP_004443467.1 Pyridoxal phosphate-dependent transferase, major region; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase YP_004443469.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Dihydroxyacid dehydratase/phosphogluconate dehydratase YP_004443470.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004443471.1 ABC transporter, nucleotide binding/ATPase protein (ribose); ABC-type sugar transport system, ATPase component YP_004443472.1 Branched-chain amino acid transport system / permease component; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004443473.1 membrane component of a putative sugar ABC transporter system; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004443474.1 GntR, C-terminal; Transcriptional regulators YP_004443475.1 Major facilitator superfamily; Arabinose efflux permease YP_004443476.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004443477.1 DNA polymerase III, alpha chain; DNA polymerase III, alpha subunit YP_004443478.1 UMUC-like DNA-repair protein; Nucleotidyltransferase/DNA polymerase involved in DNA repair YP_004443479.1 Uncharacterized conserved protein YP_004443480.1 Protein of unknown function DUF1304; Predicted membrane protein YP_004443481.1 MOFRL family; Putative glycerate kinase YP_004443483.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004443484.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004443485.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004443486.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443487.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443488.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443489.1 transcriptional regulator, ROK family; Transcriptional regulator/sugar kinase YP_004443490.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004443491.1 Uncharacterized protein conserved in bacteria YP_004443492.1 Amidase signature enzyme; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases YP_004443494.1 diguanylate cyclase (GGDEF) domain; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain YP_004443495.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004443496.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004443497.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; Septum formation topological specificity factor YP_004443498.1 Septum formation inhibitor-activating ATPase YP_004443499.1 Septum formation inhibitor MinC, C-terminal domain; Septum formation inhibitor YP_004443500.1 Predicted phosphatase/phosphohexomutase YP_004443501.1 GntR, C-terminal; Transcriptional regulators YP_004443502.1 TRAP-type C4-dicarboxylate transport system, periplasmic component YP_004443503.1 Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP-type C4-dicarboxylate transport system, small permease component YP_004443504.1 TRAP-type C4-dicarboxylate transport system, large permease component YP_004443505.1 Alcohol dehydrogenase superfamily, zinc-containing; Threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004443506.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; D-mannonate dehydratase YP_004443508.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004443509.1 TRAP dicarboxylate transporter-DctP subunit; TRAP-type C4-dicarboxylate transport system, periplasmic component YP_004443510.1 TRAP-type C4-dicarboxylate transport system, large permease component YP_004443511.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443512.1 ABC transporter, substrate-binding protein, aliphatic sulfonates family; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004443513.1 Bacterial regulatory protein, ArsR; Predicted transcriptional regulators YP_004443514.1 Glutathione S-transferase, N-terminal domain; Glutathione S-transferase YP_004443515.1 ABC transporter, nucleotide binding/ATPase protein; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004443516.1 Pyridoxal phosphate-dependent enzyme, SelA-like; Selenocysteine synthase [seryl-tRNASer selenium transferase] YP_004443517.1 Transcriptional regulator IclR, C-terminal; Transcriptional regulator YP_004443518.1 Endoribonuclease L-PSP/chorismate mutase-like; Putative translation initiation inhibitor, yjgF family YP_004443519.1 Amidohydrolase 1; Predicted amidohydrolase YP_004443520.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443521.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443522.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443524.1 Glycosyl transferase, group 1; Glycosyltransferase YP_004443525.1 Lambda repressor-like, DNA-binding; Predicted transcriptional regulators YP_004443527.1 Polysaccharide export protein; Periplasmic protein involved in polysaccharide export YP_004443528.1 Membrane-fusion protein YP_004443529.1 Acriflavin resistance protein; Cation/multidrug efflux pump YP_004443530.1 Invasion associated locus B protein; Invasion protein B, involved in pathogenesis YP_004443531.1 Outer membrane autotransporter barrel; Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain YP_004443532.1 Flavin reductase like domain; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004443533.1 Aldo/keto reductase family; Aldo/keto reductases, related to diketogulonate reductase YP_004443534.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443535.1 UbiC transcription regulator-associated; Transcriptional regulators YP_004443536.1 sugar ABC transporter, ATP-binding protein; ABC-type sugar transport systems, ATPase components YP_004443537.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443538.1 Binding-protein-dependent transport system inner membrane component; ABC-type sugar transport systems, permease components YP_004443539.1 Binding-protein-dependent transport system inner membrane component; ABC-type sugar transport system, permease component YP_004443540.1 Glycoside hydrolase, family 31; Alpha-glucosidases, family 31 of glycosyl hydrolases YP_004443542.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004443543.1 NMT1/THI5 like; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004443544.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; Hydroxyethylthiazole kinase, sugar kinase family YP_004443545.1 Thiamine monophosphate synthase YP_004443546.1 Hydroxymethylpyrimidine/phosphomethylpyrimidinekina se YP_004443547.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004443548.1 Alanine racemase, N-terminal domain YP_004443549.1 catalyzes the oxidative deamination of D-amino acids; Glycine/D-amino acid oxidases (deaminating) YP_004443550.1 GntR, C-terminal; Transcriptional regulators YP_004443552.1 RNA polymerase sigma factor 54, interaction; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains YP_004443553.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase regulating C4-dicarboxylate transport system YP_004443554.1 Sodium:dicarboxylate symporter family; Na+/H+-dicarboxylate symporters YP_004443555.1 Protein of unknown function DUF6, transmembrane; Predicted membrane protein YP_004443556.1 adenosylmethionine-8-amino-7- oxononanoatetransaminase; Adenosylmethionine-8-amino-7-oxononanoateaminotransferase YP_004443557.1 3-oxoacyl-(acyl-carrier-protein) reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443558.1 Tetratricopeptide region; FOG: TPR repeat YP_004443559.1 Peptidase M20D, amidohydrolase; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004443560.1 Tetratricopeptide-like helical YP_004443561.1 Glycosyl hydrolases family 8; Endoglucanase Y YP_004443562.1 Cellulose synthase, subunit B YP_004443563.1 Glycosyl transferase family 2; Glycosyltransferases, probably involved in cell wall biogenesis YP_004443565.1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acyl-D-glucosamine 2-epimerase YP_004443566.1 Beta-mannanase YP_004443567.1 Protein of unknown function DUF995 YP_004443568.1 Glycosyl transferase, family 2; Glycosyltransferases, probably involved in cell wall biogenesis YP_004443569.1 NAD dependent epimerase/dehydratase family YP_004443570.1 NAD dependent epimerase/dehydratase family; Nucleoside-diphosphate-sugar epimerases YP_004443572.1 Bacterial regulatory proteins, luxR family; DNA-binding HTH domain-containing proteins YP_004443576.1 Type I secretion system ATPase, PrtD; ABC-type multidrug transport system, ATPase and permease components YP_004443577.1 Type I secretion membrane fusion protein, HlyD; Membrane-fusion protein YP_004443579.1 O-antigen polymerase; Lipid A core - O-antigen ligase and related enzymes YP_004443580.1 Polysaccharide biosynthesis/export protein; Membrane-fusion protein YP_004443581.1 Bacterial sugar transferase; Sugar transferases involved in lipopolysaccharide synthesis YP_004443583.1 Cupin, RmlC-type; Mannose-6-phosphate isomerase YP_004443584.1 Adenosylmethionine-8-amino-7- oxononanoateaminotransferase YP_004443585.1 Methyl-accepting chemotaxis protein (MCP) signaling domain; Methyl-accepting chemotaxis protein YP_004443586.1 ErfK/YbiS/YcfS/YnhG; Uncharacterized protein conserved in bacteria YP_004443587.1 Bacterial protein of unknown function (DUF949); Uncharacterized protein conserved in bacteria YP_004443588.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443590.1 Methylpurine-DNA glycosylase (MPG); 3-methyladenine DNA glycosylase YP_004443593.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004443594.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443595.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443596.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443597.1 ABC transporter, nucleotide binding/ATPase protein (trehalose/maltose); ABC-type sugar transport systems, ATPase components YP_004443598.1 Protein of unknown function DUF1037; Trehalose utilization protein YP_004443599.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004443600.1 Radical SAM; Organic radical activating enzymes YP_004443601.1 6-pyruvoyl-tetrahydropterin synthase YP_004443602.1 Exoenzyme S synthesis protein B/queuosine synthesis; Predicted PP-loop superfamily ATPase YP_004443605.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004443606.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004443607.1 ABC transporter, nucleotide binding/ATPase protein; ABC-type sugar transport systems, ATPase components YP_004443608.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443609.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443610.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004443612.1 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_004443613.1 Quinonprotein alcohol dehydrogenase-like; Glucose dehydrogenase YP_004443614.1 LysR substrate binding domain; Transcriptional regulator YP_004443615.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Malic enzyme YP_004443616.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004443617.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004443618.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004443619.1 ABC transporter, nucleotide binding/ATPase protein (amino acid); ABC-type polar amino acid transport system, ATPase component YP_004443620.1 MmgE/PrpD family; Uncharacterized protein involved in propionate catabolism YP_004443621.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443622.1 Bacterial chemotaxis sensory transducer; Methyl-accepting chemotaxis protein YP_004443624.1 FAD dependent oxidoreductase; Glycine/D-amino acid oxidases (deaminating) YP_004443626.1 Cytochrome c oxidase, subunit IV, bacterial aa3 type YP_004443627.1 Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP-type mannitol/chloroaromatic compound transport system, small permease component YP_004443628.1 TRAP-type mannitol/chloroaromatic compound transport system, large permease component YP_004443629.1 TRAP dicarboxylate transporter-DctP subunit; TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component YP_004443630.1 Peptidase C26; Predicted glutamine amidotransferases YP_004443631.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004443632.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport system, ATPase component YP_004443633.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004443634.1 Peptidase M20D, amidohydrolase; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004443635.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443636.1 Beta-lactamase-type transpeptidase fold; Beta-lactamase class A YP_004443637.1 ABC transporter, nucleotide binding/ATPase protein (peptide); ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004443638.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443639.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443640.1 LysR substrate binding domain; Transcriptional regulator YP_004443641.1 Peptidase T2, asparaginase 2 YP_004443642.1 Hydantoinase/oxoprolinase; N-methylhydantoinase A/acetone carboxylase, beta subunit YP_004443643.1 Protein of unknown function DUF917; Uncharacterized conserved protein YP_004443644.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443645.1 Protein of unknown function DUF917; Uncharacterized conserved protein YP_004443646.1 Hydantoinase/oxoprolinase; N-methylhydantoinase A/acetone carboxylase, beta subunit YP_004443647.1 ABC transporter, nucleotide binding/ATPase protein (dipeptide); ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004443648.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443649.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443650.1 Winged helix repressor DNA-binding; ATP-dependent transcriptional regulator YP_004443651.1 Type I secretion membrane fusion protein, HlyD; Multidrug resistance efflux pump YP_004443652.1 Type I secretion system ATPase, PrtD; ABC-type protease/lipase transport system, ATPase and permease components YP_004443653.1 Serralysin-like metalloprotease, C-terminal YP_004443654.1 TonB-dependent heme/hemoglobin receptor family protein; Outer membrane receptor proteins, mostly Fe transport YP_004443655.1 Fe(2+)-dicitrate sensor, transmembrane component; Fe2+-dicitrate sensor, membrane component YP_004443656.1 RNA polymerase sigma factor, sigma-70 family; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004443657.1 ABC transporter, nucleotide binding/ATPase protein (iron); ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components YP_004443658.1 Bacterial transport system permease protein; ABC-type Fe3+-siderophore transport system, permease component YP_004443659.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004443660.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004443661.1 Methyltransferase type 11; SAM-dependent methyltransferases YP_004443662.1 Copper binding proteins, plastocyanin/azurin family; Plastocyanin YP_004443663.1 ABC transporter, nucleotide binding/ATPase protein (iron); ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components YP_004443664.1 Bacterial transport system permease protein; ABC-type Fe3+-siderophore transport system, permease component YP_004443665.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004443666.1 GCN5-related N-acetyltransferase; Predicted acyltransferase YP_004443667.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; Acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases YP_004443668.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Phosphoglycerate dehydrogenase and related dehydrogenases YP_004443669.1 Protein of unknown function (DUF861); Predicted enzyme of the cupin superfamily YP_004443670.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004443671.1 Isocitrate/isopropylmalate dehydrogenase YP_004443672.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004443673.1 FAD dependent oxidoreductase; Glycine/D-amino acid oxidases (deaminating) YP_004443674.1 Haloacid dehalogenase, type II; Predicted hydrolase (HAD superfamily) YP_004443675.1 GCN5-related N-acetyltransferase; Predicted acyltransferase YP_004443676.1 Adenosylmethionine-8-amino-7- oxononanoateaminotransferase YP_004443678.1 HAD-superfamily hydrolase, subfamily IA, variant 2; Predicted hydrolase (HAD superfamily) YP_004443679.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443680.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443681.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443682.1 ABC transporter, nucleotide binding/ATPase protein; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004443683.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004443684.1 FAD dependent oxidoreductase; Glycine/D-amino acid oxidases (deaminating) YP_004443685.1 Bacterial extracellular solute-binding proteins, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004443686.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004443687.1 ABC transporter, nucleotide binding/ATPase protein; ABC-type polar amino acid transport system, ATPase component YP_004443688.1 GCN5-related N-acetyltransferase YP_004443689.1 Peptidase family M20/M25/M40; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004443690.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443691.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443692.1 Transcriptional regulator, Rrf2; Predicted transcriptional regulator YP_004443693.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal YP_004443694.1 FMN-binding split barrel, related; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004443695.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443697.1 Alpha/Beta hydrolase family of unknown function (DUF1234); Predicted esterase of the alpha/beta hydrolase fold YP_004443698.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443699.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004443700.1 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004443701.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443702.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443703.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443704.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004443705.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type oligopeptide transport system, ATPase component YP_004443706.1 Aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004443707.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004443708.1 LysR, substrate-binding; Transcriptional regulator YP_004443709.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443710.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443712.1 Bacterial extracellular solute-binding proteins, family 5 Middle; ABC-type dipeptide transport system, periplasmic component YP_004443713.1 Peptidase M20D, amidohydrolase; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004443714.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443715.1 NmrA-like; Predicted nucleoside-diphosphate-sugar epimerases YP_004443716.1 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004443717.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443718.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443719.1 Mandelate racemase/muconate lactonizing enzyme; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004443720.1 Esterase, SGNH hydrolase-type; Lysophospholipase L1 and related esterases YP_004443721.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004443722.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type oligopeptide transport system, ATPase component YP_004443723.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004443724.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443725.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004443727.1 Lysine exporter protein (LYSE/YGGA); Putative threonine efflux protein YP_004443728.1 GntR, C-terminal; Transcriptional regulators YP_004443729.1 Bacterial regulatory helix-turn-helix proteins, AraC family; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_004443730.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004443731.1 Short-chain dehydrogenases of various substrate specificities YP_004443733.1 Beta-lactamase-like; Zn-dependent hydrolases, including glyoxylases YP_004443734.1 Bacterial regulatory protein, arsR family; Predicted transcriptional regulators YP_004443735.1 Protein of unknown function DUF395, YeeE/YedE; Predicted transporter component YP_004443736.1 Protein of unknown function DUF395, YeeE/YedE; Predicted transporter component YP_004443737.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; Phosphoglyceromutase YP_004443738.1 branched-chain alpha-keto acid dehydrogenase subunit E2; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes YP_004443739.1 Transketolase, pyrimidine binding domain; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit YP_004443740.1 Dehydrogenase E1 component; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit YP_004443741.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004443742.1 Thiolase, N-terminal domain; Acetyl-CoA acetyltransferase YP_004443743.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004443744.1 Isovaleryl-CoA dehydrogenase is an is an acyl-CoA dehydrogenase, which catalyzes the third step in leucine catabolism, the conversion of isovaleryl-CoA (3-methylbutyryl-CoA) into 3-methylcrotonyl-CoA. IVD is a homotetramer and has the greatest affinity for small branched chain substrates; Acyl-CoA dehydrogenases YP_004443745.1 Carboxyl transferase domain; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) YP_004443746.1 Biotin carboxylation region, Carbamoyl-phosphate synthase L chain, ATP binding domain; Acetyl/propionyl-CoA carboxylase, alpha subunit YP_004443747.1 Isopropylmalate/homocitrate/citramalatesynthases YP_004443748.1 Enoyl-CoA hydratase/isomerase family; Enoyl-CoA hydratase/carnithine racemase YP_004443749.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; Panthothenate synthetase YP_004443750.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; Ketopantoate hydroxymethyltransferase YP_004443751.1 L-rhamnose catabolism isomerase; Predicted sugar isomerase YP_004443752.1 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; Uncharacterized conserved protein YP_004443753.1 Bacterial regulatory proteins, deoR family; Transcriptional regulators of sugar metabolism YP_004443754.1 Rhamnose ABC transporter, rhamnose-binding; ABC-type sugar transport system, periplasmic component YP_004443755.1 ABC transporter, nucleotide binding/ATPase protein; ABC-type sugar transport system, ATPase component YP_004443756.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004443757.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004443758.1 Protein of unknown function (DUF718); Uncharacterized conserved protein YP_004443759.1 Carbohydrate kinase, FGGY; Sugar (pentulose and hexulose) kinases YP_004443760.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004443761.1 Methyltransferase FkbM; SAM-dependent methyltransferases YP_004443762.1 diguanylate cyclase (GGDEF) domain; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain YP_004443763.1 Oxidoreductase, molybdopterin binding; Sulfite oxidase and related enzymes YP_004443764.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004443765.1 DNA alkylation repair enzyme YP_004443766.1 Sulphate transport system permease; ABC-type sulfate/molybdate transport systems, ATPase component YP_004443767.1 Sulphate ABC transporter permease protein; ABC-type sulfate transport system, permease component YP_004443768.1 Sulphate ABC transporter permease protein; ABC-type sulfate transport system, permease component YP_004443769.1 sulfate ABC transporter, sulfate-binding protein; ABC-type sulfate transport system, periplasmic component YP_004443770.1 Enoyl-CoA hydratase/isomerase family; Enoyl-CoA hydratase/carnithine racemase YP_004443772.1 Bacterial SH3 domain; Uncharacterized protein with a bacterial SH3 domain homologue YP_004443773.1 Involved in ubiquinone biosynthesis; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4- benzoquinol methylase YP_004443774.1 Protein of unknown function DUF1178; Uncharacterized protein conserved in bacteria YP_004443775.1 Nitrilase/cyanide hydratase and apolipoprotein; Predicted amidohydrolase YP_004443776.1 Glutaredoxin, GrxC; Glutaredoxin and related proteins YP_004443777.1 biotin biosynthesis protein BioC; SAM-dependent methyltransferases YP_004443778.1 Flp/Fap pilin component YP_004443780.1 Mutator MutT; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004443781.1 GCN5-related N-acetyltransferase; Sortase and related acyltransferases YP_004443782.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; N-acetylglutamate synthase (N-acetylornithine aminotransferase) YP_004443783.1 Peptidyl-prolyl cis-trans isomerase, PpiC-type; Parvulin-like peptidyl-prolyl isomerase YP_004443784.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; Preprotein translocase subunit SecA (ATPase, RNA helicase) YP_004443785.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004443786.1 required for the transfer of succinyl residues to the glucan backbone; Uncharacterized protein conserved in bacteria YP_004443787.1 Polysaccharide biosynthesis protein; Membrane protein involved in the export of O- antigen and teichoic acid YP_004443788.1 Protein involved in cellulose biosynthesis (CelD) YP_004443790.1 Disulphide bond formation protein DsbB; Disulfide bond formation protein DsbB YP_004443791.1 HNH nuclease; Restriction endonuclease YP_004443793.1 Bacterial protein of unknown function (DUF920); Predicted periplasmic protein YP_004443794.1 Metallophosphoesterase; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases YP_004443795.1 Glycosyl transferase, group 1 YP_004443796.1 Uncharacterized conserved protein YP_004443797.1 Polysaccharide biosynthesis protein; Membrane protein involved in the export of O- antigen and teichoic acid YP_004443799.1 Glycosyl transferase, group 1 YP_004443802.1 Acyltransferase family; Predicted acyltransferases YP_004443804.1 Exopolysaccharide transport protein; Uncharacterized protein involved in exopolysaccharide biosynthesis YP_004443807.1 Glycosyl transferases group 1 YP_004443808.1 Glycosyl transferases group 1 YP_004443809.1 Glycosyl transferase, group 1 YP_004443810.1 Esterase, SGNH hydrolase-type YP_004443812.1 Transcription elongation factor, GreA/GreB region, prokaryotic YP_004443813.1 Concanavalin A-like lectin/glucanase, subgroup; Beta-glucanase/Beta-glucan synthetase YP_004443814.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004443815.1 Glycerophosphoryl diester phosphodiesterase family YP_004443816.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004443817.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004443818.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004443819.1 Bacterial extracellular solute-binding protein, family 1; Maltose-binding periplasmic proteins/domains YP_004443820.1 ROK; Transcriptional regulator/sugar kinase YP_004443823.1 Bacterial transcriptional activator domain; DNA-binding transcriptional activator of the SARP family YP_004443825.1 YcaO-like family; Uncharacterized conserved protein YP_004443826.1 TfuA-like protein; Uncharacterized conserved protein YP_004443828.1 Lambda repressor-like, DNA-binding; Predicted transcriptional regulators YP_004443830.1 ABC transporter, nucleotide binding/ATPase protein (xylose); ABC-type sugar transport system, ATPase component YP_004443831.1 Bacterial inner-membrane translocator; ABC-type xylose transport system, permease component YP_004443832.1 D-xylose ABC transporter, substrate-binding protein; ABC-type xylose transport system, periplasmic component YP_004443833.1 ROK; Transcriptional regulator/sugar kinase YP_004443834.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_004443835.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004443836.1 MDM; functions in conversion of succinate to propionate; Methylmalonyl-CoA mutase, N-terminal domain/subunit YP_004443837.1 Biotin carboxylation region, Carbamoyl-phosphate synthase L chain, ATP binding domain; Acetyl/propionyl-CoA carboxylase, alpha subunit YP_004443839.1 Glutathione S-transferase, C-terminal-like YP_004443840.1 Carboxyl transferase domain; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) YP_004443841.1 Protein of unknown function DUF955; Predicted transcriptional regulator YP_004443842.1 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase YP_004443843.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; Glutamyl- and glutaminyl-tRNA synthetases YP_004443844.1 Ribonuclease BN-like family; Predicted membrane protein YP_004443845.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004443847.1 Cobalamin adenosyltransferase; cob(I)alamin adenosyltransferase YP_004443848.1 Peptidase S54, rhomboid; Uncharacterized membrane protein (homolog of Drosophila rhomboid) YP_004443849.1 Electron transfer flavoprotein, beta subunit YP_004443850.1 Electron transfer flavoprotein, alpha subunit YP_004443851.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxyacyl-CoA dehydrogenase YP_004443852.1 Thioredoxin-like fold; Thiol-disulfide isomerase and thioredoxins YP_004443853.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_004443856.1 Conserved hypothetical protein CHP02302, transmembrane YP_004443857.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443858.1 Hypoxanthine phosphoribosyl transferase; Hypoxanthine-guanine phosphoribosyltransferase YP_004443860.1 cell division ATP-binding protein FtsE; Predicted ATPase involved in cell division YP_004443862.1 Protein of unknown function DUF218; Uncharacterized conserved protein YP_004443863.1 Phospholipid/glycerol acyltransferase YP_004443864.1 ChaC-like protein; Uncharacterized protein involved in cation transport YP_004443865.1 Uncharacterized protein conserved in bacteria YP_004443866.1 GCN5-related N-acetyltransferase; Acetyltransferases YP_004443867.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; Prephenate dehydrogenase YP_004443868.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase YP_004443869.1 Methyltransferase type 11; Methylase involved in ubiquinone/menaquinone biosynthesis YP_004443870.1 Metallo-beta-lactamase superfamily; Zn-dependent hydrolases, including glyoxylases YP_004443871.1 Protein of unknown function DUF985; Uncharacterized conserved protein YP_004443873.1 required for 70S ribosome assembly; Ribosomal protein L28 YP_004443874.1 Protein of unknown function DUF165; Uncharacterized conserved protein YP_004443875.1 Pentapeptide repeat; Uncharacterized low-complexity proteins YP_004443876.1 Uncharacterised conserved protein UCP031900; Uncharacterized protein conserved in bacteria YP_004443877.1 Cobalt chelatase, CobT subunit; Cobalamin biosynthesis protein CobT (nicotinate- mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) YP_004443878.1 Cobalt chelatase, pCobS small subunit; MoxR-like ATPases YP_004443879.1 Heat shock protein DnaJ, N-terminal; DnaJ-class molecular chaperone YP_004443880.1 Stress-induced morphogen (activity unknown) YP_004443881.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthetase YP_004443882.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_004443884.1 Site-specific recombinase XerD YP_004443885.1 Acetyl-CoA carboxylase, alpha subunit; Acetyl-CoA carboxylase alpha subunit YP_004443886.1 Protein of unknown function DUF949, bacterial; Uncharacterized protein conserved in bacteria YP_004443887.1 SirA-like protein; Predicted redox protein, regulator of disulfide bond formation YP_004443888.1 Cobalamin (vitamin B12) biosynthesis CobW-like; Putative GTPases (G3E family) YP_004443889.1 Beta-lactamase-type transpeptidase fold; D-alanyl-D-alanine carboxypeptidase YP_004443890.1 Peptidase family M20/M25/M40; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004443892.1 Penicillin-binding protein 1C; Membrane carboxypeptidase/penicillin-binding protein PbpC YP_004443893.1 Alpha-2-macroglobulin family N-terminal region; Large extracellular alpha-helical protein YP_004443894.1 Protein of unknown function DUF343 YP_004443895.1 Peptidase S16, lon N-terminal; Uncharacterized protein, similar to the N- terminal domain of Lon protease YP_004443896.1 Tetratricopeptide-like helical; Thioredoxin domain-containing protein YP_004443897.1 Uncharacterized conserved protein YP_004443898.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; Predicted tRNA(5-methylaminomethyl-2- thiouridylate) methyltransferase, contains the PP-loop ATPase domain YP_004443899.1 Uncharacterized conserved protein UPC028704; Uncharacterized protein conserved in bacteria YP_004443900.1 Mitochondrial import inner membrane translocase, subunit Tim44; Uncharacterized protein conserved in bacteria YP_004443901.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Phosphoglycerate dehydrogenase and related dehydrogenases YP_004443902.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_004443903.1 Outer membrane protein, beta-barrel; Opacity protein and related surface antigens YP_004443904.1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Phosphomannomutase YP_004443905.1 Peptidase M41, FtsH; ATP-dependent Zn proteases YP_004443906.1 Lysidine-tRNA(Ile) synthetase, N-terminal; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control YP_004443907.1 Tol-Pal system, YbgF; Uncharacterized protein conserved in bacteria YP_004443908.1 Outer membrane protein, OmpA/MotB, C-terminal; Outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_004443909.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; Periplasmic component of the Tol biopolymer transport system YP_004443911.1 Biopolymer transport protein ExbD/TolR; Biopolymer transport protein YP_004443912.1 MotA/TolQ/ExbB proton channel family; Biopolymer transport proteins YP_004443913.1 Pol-Pal system-associated acyl-CoA thioesterase; Predicted thioesterase YP_004443914.1 NUDIX domain; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004443915.1 NUDIX domain; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004443916.1 DinB family; Uncharacterized protein conserved in bacteria YP_004443918.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction resolvasome, helicase subunit YP_004443919.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction resolvasome, DNA-binding subunit YP_004443920.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvasome, endonuclease subunit YP_004443921.1 Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004443922.1 Luciferase-like monooxygenase; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004443923.1 Protein of unknown function DUF28; Uncharacterized conserved protein YP_004443924.1 FMN-binding split barrel, related; Uncharacterized stress protein (general stress protein 26) YP_004443925.1 Predicted Zn-dependent hydrolases of the beta- lactamase fold YP_004443926.1 Conserved hypothetical protein CHP00282; Uncharacterized protein conserved in bacteria YP_004443927.1 5-formyltetrahydrofolate cyclo-ligase family YP_004443928.1 Protein of unknown function DUF21; Hemolysins and related proteins containing CBS domains YP_004443929.1 Protein of unknown function DUF710; Uncharacterized protein conserved in bacteria YP_004443931.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_004443932.1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase YP_004443935.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain YP_004443936.1 3-phosphoglycerate kinase YP_004443937.1 Fructose-bisphosphate aldolase class-I; Fructose-1,6-bisphosphate aldolase YP_004443939.1 Major facilitator superfamily MFS-1; Permeases of the major facilitator superfamily YP_004443940.1 Protein of unknown function DUF1192; Uncharacterized small protein containing a coiled-coil domain YP_004443941.1 Protein of unknown function DUF1465; Uncharacterized protein conserved in bacteria YP_004443942.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; Ribosomal protein L31 YP_004443943.1 ABC transporter, permease/ATP-binding protein; ABC-type multidrug transport system, ATPase and permease components YP_004443944.1 proposed role in polysaccahride synthesis; Predicted oxidoreductase YP_004443945.1 Outer membrane protein, OmpA/MotB, C-terminal YP_004443947.1 extragenic suppressor protein SuhB; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004443948.1 Tetratricopeptide-like helical; FOG: TPR repeat, SEL1 subfamily YP_004443949.1 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole; Thiamine monophosphate synthase YP_004443950.1 Protein of unknown function DUF81; Predicted permeases YP_004443951.1 Protein of unknown function DUF465 YP_004443952.1 Protein of unknown function DUF465 YP_004443953.1 1-(5-Phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase YP_004443954.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) YP_004443955.1 smallest protein in the large subunit; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_004443956.1 Tetratricopeptide-like helical; FOG: TPR repeat YP_004443957.1 tRNA-binding arm YP_004443958.1 Protein of unknown function DUF1244; Uncharacterized protein conserved in bacteria YP_004443959.1 N-formylglutamate amidohydrolase; Predicted N-formylglutamate amidohydrolase YP_004443960.1 Protein of unknown function DUF1036; Predicted integral membrane protein YP_004443961.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_004443962.1 Protein of unknown function DUF882, bacterial; Uncharacterized protein conserved in bacteria YP_004443963.1 Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains YP_004443964.1 Peptidase M3B, oligoendopeptidase-related clade 3 YP_004443965.1 Aminotransferase, class IV; Branched-chain amino acid aminotransferase/4- amino-4-deoxychorismate lyase YP_004443966.1 diguanylate cyclase (GGDEF) domain; c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) YP_004443969.1 5'-nucleotidase, C-terminal domain; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases YP_004443970.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; Protoheme ferro-lyase (ferrochelatase) YP_004443971.1 SPFH domain / Band 7 family; Membrane protease subunits, stomatin/prohibitin homologs YP_004443972.1 Nodulation efficiency, NfeD; Membrane protein implicated in regulation of membrane protease activity YP_004443973.1 sugar isomerase, KpsF/GutQ family; Predicted sugar phosphate isomerase involved in capsule formation YP_004443974.1 PAS fold-3; FOG: PAS/PAC domain YP_004443977.1 Uncharacterized protein conserved in bacteria YP_004443978.1 Nucleotidyl transferase; UDP-glucose pyrophosphorylase YP_004443979.1 Lytic murein transglycosylase; Membrane-bound lytic murein transglycosylase B YP_004443980.1 Protein of unknown function DUF459; Uncharacterized protein conserved in bacteria YP_004443981.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443982.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004443983.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; NADPH-dependent glutamate synthase beta chain and related oxidoreductases YP_004443985.1 Conserved region in glutamate synthase; Glutamate synthase domain 2 YP_004443986.1 Pyridoxal phosphate-dependent transferase, major region; Threonine aldolase YP_004443987.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004443988.1 Osmosensitive K+ channel His kinase sensor domain; Osmosensitive K+ channel histidine kinase YP_004443989.1 Potassium-binding and translocating subunit C; K+-transporting ATPase, c chain YP_004443990.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; High-affinity K+ transport system, ATPase chain B YP_004443991.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; K+-transporting ATPase, A chain YP_004443992.1 K+-transporting ATPase, F subunit YP_004443995.1 Asparaginase/glutaminase; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D YP_004443996.1 Amino acid/polyamine transporter I; Gamma-aminobutyrate permease and related permeases YP_004443997.1 L-Aspartase-like YP_004443998.1 GntR, C-terminal; Transcriptional regulators YP_004443999.1 Cation/multidrug efflux pump YP_004444000.1 Secretion protein HlyD; Membrane-fusion protein YP_004444001.1 Secretion protein HlyD; Membrane-fusion protein YP_004444002.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; Transcriptional regulator YP_004444004.1 Fatty acid desaturase, type 1 YP_004444006.1 Cupin, RmlC-type; Uncharacterized conserved protein, contains double-stranded beta-helix domain YP_004444007.1 Tautomerase; Uncharacterized protein, 4-oxalocrotonate tautomerase homolog YP_004444008.1 LysR substrate binding domain; Transcriptional regulator YP_004444009.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004444010.1 Lysine exporter protein (LYSE/YGGA); Putative threonine efflux protein YP_004444011.1 Aldehyde dehydrogenase; NAD-dependent aldehyde dehydrogenases YP_004444012.1 ABC transporter, nucleotide binding/ATPase protein (polyamine); ABC-type spermidine/putrescine transport systems, ATPase components YP_004444013.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component II YP_004444014.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component I YP_004444015.1 Bacterial extracellular solute-binding protein, family 1; Spermidine/putrescine-binding periplasmic protein YP_004444016.1 NIPSNAP YP_004444017.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004444018.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004444019.1 FMN-binding split barrel, related; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004444020.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004444021.1 Protein of unknown function DUF1185 YP_004444022.1 Iron-containing alcohol dehydrogenase; Alcohol dehydrogenase, class IV YP_004444023.1 glutamate/aspartate transport ATP-binding protein; ABC-type polar amino acid transport system, ATPase component YP_004444024.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004444025.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004444026.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004444027.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; Formyltetrahydrofolate hydrolase YP_004444028.1 Glutamine synthetase/guanido kinase, catalytic region; Glutamine synthetase YP_004444029.1 Conserved region in glutamate synthase; Glutamate synthase domain 2 YP_004444030.1 Formylmethanofuran dehydrogenase subunit C YP_004444031.1 Glutamine amidotransferase, class-II; Glutamate synthase domain 1 YP_004444032.1 Cupin, RmlC-type; Predicted transcriptional regulators YP_004444034.1 Dihydrodipicolinate synthetase family; Dihydrodipicolinate synthase/N- acetylneuraminate lyase YP_004444035.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004444036.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444037.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444038.1 Bacterial extracellular solute-binding proteins, family 5 Middle; ABC-type dipeptide transport system, periplasmic component YP_004444040.1 Neuraminidase; Predicted neuraminidase (sialidase) YP_004444041.1 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA YP_004444042.1 Alcohol dehydrogenase, class IV YP_004444043.1 GntR, C-terminal; Transcriptional regulators YP_004444044.1 Uncharacterized protein conserved in bacteria YP_004444045.1 Glycoside hydrolase/deacetylase, beta/alpha-barrel; Predicted xylanase/chitin deacetylase YP_004444046.1 ATP-grasp fold YP_004444047.1 Thioesterase superfamily YP_004444049.1 ABC transporter, transmembrane region, type 1; ABC-type uncharacterized transport system, permease and ATPase components YP_004444050.1 Bacterial transglutaminase-like N-terminal region; Uncharacterized protein conserved in bacteria YP_004444051.1 Protein of unknown function DUF404, bacteria N-terminal; Uncharacterized conserved protein YP_004444052.1 Bacterial transglutaminase-like N-terminal region; Transglutaminase-like enzymes, putative cysteine proteases YP_004444053.1 von Willebrand factor, type A; Flp pilus assembly protein TadG YP_004444054.1 ABC transporter, nucleotide binding/ATPase protein; ATPase components of ABC transporters with duplicated ATPase domains YP_004444055.1 Alpha-hydroxy acid dehydrogenase, FMN-dependent; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases YP_004444056.1 GCN5-related N-acetyltransferase; Transcriptional regulators YP_004444057.1 Methyl-accepting chemotaxis protein (MCP) signaling domain; Methyl-accepting chemotaxis protein YP_004444058.1 Carbohydrate kinase, FGGY; Glycerol kinase YP_004444059.1 Aldolase-type TIM barrel; DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes YP_004444060.1 FAD dependent oxidoreductase YP_004444061.1 aldo/keto reductase family; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004444062.1 putative sugar-binding region; Transcriptional regulator, contains sigma factor-related N-terminal domain YP_004444063.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004444064.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004444065.1 ABC transporter, substrate binding protein (sugar); ABC-type sugar transport system, periplasmic component YP_004444067.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004444069.1 Inositol monophosphatase family; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004444070.1 Alpha/beta hydrolase fold-1; Lysophospholipase YP_004444071.1 Hsp20/alpha crystallin family; Molecular chaperone (small heat shock protein) YP_004444072.1 Bile acid:sodium symporter; Predicted Na+-dependent transporter YP_004444073.1 LysR substrate binding domain; Transcriptional regulator YP_004444075.1 ABC transporter, periplasmic substrate-binding protein; ABC-type sugar transport system, periplasmic component YP_004444076.1 Predicted small integral membrane protein YP_004444077.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004444078.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004444079.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004444080.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004444081.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_004444082.1 Bacterial regulatory proteins, deoR family; Transcriptional regulators of sugar metabolism YP_004444083.1 Uroporphyrin-III C-methyltransferase, C-terminal; Uroporphyrinogen-III methylase YP_004444084.1 Molybdopterin oxidoreductase; Anaerobic dehydrogenases, typically selenocysteine-containing YP_004444085.1 Nitrite reductase [NAD(P)H] large subunit, NirD; Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases YP_004444086.1 Nitrite reductase [NAD(P)H] large subunit, NirB; NAD(P)H-nitrite reductase YP_004444087.1 nitrate ABC transporter, ATP-binding proteins C and D; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004444088.1 ABC transporter, membrane spanning protein (nitrate); ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004444089.1 ABC transporter, substrate binding protein (nitrate); ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004444090.1 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004444091.1 Response regulator antiterminator; Response regulator with putative antiterminator output domain YP_004444092.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004444093.1 Natural resistance-associated macrophage protein; Mn2+ and Fe2+ transporters of the NRAMP family YP_004444094.1 LamB/YcsF family; Uncharacterized proteins, homologs of lactam utilization protein B YP_004444095.1 Protein of unknown function DUF1445; Uncharacterized conserved protein YP_004444096.1 Allophanate hydrolase subunit 2 YP_004444097.1 Biotin carboxylation region; Acetyl/propionyl-CoA carboxylase, alpha subunit YP_004444098.1 converts 1,4-alpha-D-glucans to maltodextrin; Glycosidases YP_004444099.1 Predicted transcriptional regulators YP_004444100.1 TonB-dependent receptor, beta-barrel, exogenous ferric siderophore receptor; Outer membrane receptor for ferrienterochelin and colicins YP_004444101.1 Glycosyl transferase, family 3; Anthranilate phosphoribosyltransferase YP_004444102.1 Bacterial low temperature requirement A protein; Predicted membrane protein YP_004444105.1 Replication protein C YP_004444106.1 ParB-like partition protein; Predicted transcriptional regulators YP_004444107.1 CobQ/CobB/MinD/ParA nucleotide binding domain; ATPases involved in chromosome partitioning YP_004444108.1 Uncharacterized protein conserved in bacteria YP_004444109.1 Endoribonuclease L-PSP/chorismate mutase-like; Putative translation initiation inhibitor, yjgF family YP_004444110.1 Alanine racemase, N-terminal domain; Predicted amino acid aldolase or racemase YP_004444111.1 Protein of unknown function (DUF1485); Uncharacterized conserved protein YP_004444112.1 Bacterial protein of unknown function (DUF886); Uncharacterized protein conserved in bacteria YP_004444113.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004444114.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_004444116.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_004444117.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Imidazolonepropionase and related amidohydrolases YP_004444118.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glu; Cytosine deaminase and related metal-dependent hydrolases YP_004444119.1 Transcriptional regulators YP_004444121.1 acetyl-CoA carboxylase, biotin carboxyl carrier protein; Biotin carboxyl carrier protein YP_004444122.1 Acetyl-CoA carboxylase, biotin carboxylase; Biotin carboxylase YP_004444123.1 Single hybrid motif YP_004444124.1 Conserved hypothetical protein CHP00370; Allophanate hydrolase subunit 1 YP_004444125.1 Allophanate hydrolase subunit 2 YP_004444126.1 LamB/YcsF family; Uncharacterized proteins, homologs of lactam utilization protein B YP_004444127.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Aspartate/tyrosine/aromatic aminotransferase YP_004444128.1 LysR substrate binding domain, NAC (nitrogen assimilation control protein); Transcriptional regulator YP_004444129.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444130.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004444131.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004444132.1 ABC transporter, nucleotide binding/ATPase protein; ABC-type polar amino acid transport system, ATPase component YP_004444133.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004444134.1 Ribonuclease E inhibitor RraA/Dimethylmenaquinone; Demethylmenaquinone methyltransferase YP_004444135.1 Arginase family; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family YP_004444136.1 amino acid ABC transporter; ABC-type polar amino acid transport system, ATPase component YP_004444137.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004444138.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004444139.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004444140.1 LysR substrate binding domain; Transcriptional regulator YP_004444141.1 Bacterial regulatory protein, ArsR; Predicted transcriptional regulators YP_004444142.1 Major facilitator superfamily MFS-1; Permeases of the major facilitator superfamily YP_004444143.1 Arsenate resistance ArsH; Predicted flavoprotein YP_004444144.1 Arsenate reductase and related proteins, glutaredoxin family YP_004444145.1 sodium bile acid symporter family protein; Arsenite efflux pump ACR3 and related permeases YP_004444146.1 Bacterial regulatory protein, ArsR; Predicted transcriptional regulators YP_004444147.1 Ribonuclease E inhibitor RraA/Dimethylmenaquinone YP_004444148.1 Nucleoside-diphosphate-sugar epimerases YP_004444149.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Dihydroxyacid dehydratase/phosphogluconate dehydratase YP_004444150.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004444151.1 Binding-protein-dependent transport system inner membrane component; ABC-type sugar transport system, permease component YP_004444152.1 Binding-protein-dependent transport system inner membrane component; ABC-type sugar transport systems, permease components YP_004444153.1 Bacterial extracellular solute-binding protein; ABC-type sugar transport system, periplasmic component YP_004444154.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004444155.1 Oxidoreductase, C-terminal; Predicted dehydrogenases and related proteins YP_004444156.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004444157.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004444158.1 SMP-30/Gluconolaconase/LRE-like region; Gluconolactonase YP_004444159.1 NUDIX domain; NTP pyrophosphohydrolases including oxidative damage repair enzymes YP_004444160.1 Phenazine biosynthesis PhzC/PhzF protein; Predicted epimerase, PhzC/PhzF homolog YP_004444161.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_004444162.1 oxygenase (tetracycline 6-hydroxylase) protein YP_004444163.1 LysR substrate binding domain; Transcriptional regulator YP_004444164.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004444165.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004444166.1 sulfonate monooxygenase; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004444167.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004444168.1 ABC transporter related; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004444169.1 ABC transporter membrane spanning protein (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444170.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444171.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004444172.1 Molybdopterin oxidoreductase; Anaerobic dehydrogenases, typically selenocysteine-containing YP_004444173.1 FAD linked oxidases, C-terminal domain; FAD/FMN-containing dehydrogenases YP_004444174.1 HCCA isomerase/glutathione S-transferase kappa; Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis YP_004444175.1 Tetracycline transcriptional regulator, TetR-related, C-terminal; Transcriptional regulator YP_004444176.1 Ketopantoate reductase PanE/ApbA YP_004444177.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004444178.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004444179.1 PAP2 superfamily protein YP_004444180.1 Uncharacterized conserved protein YP_004444181.1 Cupredoxin; Uncharacterized copper-binding protein YP_004444182.1 Putative multicopper oxidases YP_004444183.1 Outer membrane protein YP_004444187.1 AraC protein, arabinose-binding/dimerisation; AraC-type DNA-binding domain-containing proteins YP_004444188.1 GCN5-related N-acetyltransferase; Acetyltransferases YP_004444189.1 Biotin and Thiamin Synthesis associated domain; Biotin synthase and related enzymes YP_004444190.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 7-keto-8-aminopelargonate synthetase and related enzymes YP_004444191.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; Dethiobiotin synthetase YP_004444192.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_004444193.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-[acyl-carrier-protein] synthase III YP_004444194.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004444195.1 Arginase family; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family YP_004444196.1 Ornithine cyclodeaminase/mu-crystallin family; Predicted ornithine cyclodeaminase, mu- crystallin homolog YP_004444197.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004444199.1 Predicted dehydrogenases and related proteins YP_004444201.1 Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylate cyclase, family 3 (some proteins contain HAMP domain) YP_004444202.1 Lambda repressor-like, DNA-binding YP_004444203.1 Protein of unknown function DUF1612 YP_004444204.1 MFS transporter, metabolite:H+ symporter (MHS) family protein; Permeases of the major facilitator superfamily YP_004444205.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004444206.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004444207.1 Predicted membrane-associated, metal-dependent hydrolase YP_004444209.1 LysR substrate binding domain; Transcriptional regulator YP_004444210.1 TonB-dependent siderophore receptor; Outer membrane receptor proteins, mostly Fe transport YP_004444211.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004444212.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; ABC-type Fe3+-siderophore transport system, permease component YP_004444213.1 ABC transporter, nucleotide binding/ATPase protein (ferrichrome); ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components YP_004444214.1 Protein of unknown function DUF992 YP_004444215.1 Cytochrome c, class IA/ IB YP_004444216.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; Uncharacterized protein conserved in bacteria YP_004444217.1 Six-bladed beta-propeller, TolB-like; Gluconolactonase YP_004444218.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004444219.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004444220.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport system, ATPase component YP_004444221.1 ABC transporter, substrate binding protein (sugar); ABC-type sugar transport system, periplasmic component YP_004444222.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004444223.1 Response regulator receiver domain; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_004444224.1 DNA breaking-rejoining enzyme, catalytic core; Topoisomerase IB YP_004444225.1 Soluble quinoprotein glucose dehydrogenase; Glucose/sorbosone dehydrogenases YP_004444227.1 Protein of unknown function DUF548 YP_004444228.1 Pseudouridylate synthases, 23S RNA-specific YP_004444229.1 Protein of unknown function UPF0029, N-terminal; Uncharacterized conserved protein YP_004444230.1 HI0933-like protein; Predicted flavoproteins YP_004444231.1 Glycine betaine/L-proline transport ATP-binding subunit, ABC transporter; ABC-type proline/glycine betaine transport system, ATPase component YP_004444232.1 Binding-protein-dependent transport systems inner membrane component; ABC-type proline/glycine betaine transport system, permease component YP_004444233.1 Substrate-binding region of ABC-type glycine betaine transport system; ABC-type proline/glycine betaine transport systems, periplasmic components YP_004444234.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004444235.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Phosphoglycerate dehydrogenase and related dehydrogenases YP_004444236.1 Exopolysaccharide transport protein; Uncharacterized protein involved in exopolysaccharide biosynthesis YP_004444237.1 UDP-glucose pyrophosphorylase YP_004444238.1 Glycosyl transferase family 2; Glycosyltransferases involved in cell wall biogenesis YP_004444239.1 Glycosyl transferase family 2; Glycosyltransferases involved in cell wall biogenesis YP_004444240.1 Glycosyl transferase family 2; Glycosyltransferases, probably involved in cell wall biogenesis YP_004444242.1 Concanavalin A-like lectin/glucanase (licheninase); Beta-glucanase/Beta-glucan synthetase YP_004444243.1 Succinoglycan biosynthesis protein exoH; Predicted acyltransferases YP_004444245.1 Polysaccharide biosynthesis protein; Membrane protein involved in the export of O- antigen and teichoic acid YP_004444246.1 Glycosyl transferase family 2; Glycosyltransferases involved in cell wall biogenesis YP_004444247.1 ExoV-like protein YP_004444248.1 Glycosyl transferase family 2; Glycosyltransferases involved in cell wall biogenesis YP_004444251.1 Tetratricopeptide-like helical; FOG: TPR repeat YP_004444252.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; Ribosomal protein S21 YP_004444253.1 Sarcosine oxidase, beta subunit, heterotetrameric; Glycine/D-amino acid oxidases (deaminating) YP_004444255.1 Sarcosine oxidase, delta subunit, heterotetrameric YP_004444256.1 Sarcosine oxidase, alpha subunit, heterotetrameric; Glycine cleavage system T protein (aminomethyltransferase) YP_004444257.1 Sarcosine oxidase, gamma subunit, heterotetrameric YP_004444258.1 Uncharacterised conserved protein UCP012608; Uncharacterized protein conserved in bacteria YP_004444259.1 Bacterial extracellular solute-binding protein, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004444260.1 MaoC-like dehydratase; Acyl dehydratase YP_004444261.1 Glycogen debranching enzyme GlgX; Type II secretory pathway, pullulanase PulA and related glycosidases YP_004444262.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_004444263.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_004444264.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; ADP-glucose pyrophosphorylase YP_004444265.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; 1,4-alpha-glucan branching enzyme YP_004444266.1 Glycosyl transferase, family 35; Glucan phosphorylase YP_004444268.1 Glutamine amidotransferase, class-II; Predicted glutamine amidotransferase YP_004444270.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004444271.1 Glycoside hydrolase-type carbohydrate-binding; Galactose mutarotase and related enzymes YP_004444272.1 3-hydroxyacid dehydrogenase/reductase; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_004444273.1 catalyzes the formation of 5-dehydro-D-gluconate from D-gluconate; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444274.1 Alcohol dehydrogenase superfamily, zinc-containing; Threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004444275.1 Winged helix repressor DNA-binding; Predicted transcriptional regulators YP_004444276.1 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; ABC-type multidrug transport system, ATPase and permease components YP_004444277.1 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components YP_004444278.1 Cytochrome bd ubiquinol oxidase, subunit I; Cytochrome bd-type quinol oxidase, subunit 1 YP_004444279.1 Cytochrome bd ubiquinol oxidase, subunit II; Cytochrome bd-type quinol oxidase, subunit 2 YP_004444280.1 Cyd operon protein YbgT YP_004444283.1 Transglycosylase-associated protein YP_004444284.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Nicotinate-nucleotide pyrophosphorylase YP_004444285.1 catalyzes the formation of oxaloacetate from L-aspartate; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit YP_004444286.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; Quinolinate synthase YP_004444287.1 Nicotinic acid mononucleotide biosynthesis protein; Uncharacterized conserved protein YP_004444288.1 PAS fold-3 YP_004444290.1 Conserved hypothetical protein FYDLN acid; Uncharacterized protein conserved in bacteria YP_004444291.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_004444292.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Ribosomal protein S1 YP_004444296.1 3'-5' exonuclease YP_004444298.1 Short-chain dehydrogenase/reductase SDR; hort-chain alcohol dehydrogenase of unknown specificity YP_004444300.1 Peptidase M24, catalytic core; Xaa-Pro aminopeptidase YP_004444301.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004444302.1 ABC transporter, membrane spanning protein (dipeptide) YP_004444303.1 ABC transporter, membrane spanning protein (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444304.1 Binding-protein-dependent transport system inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444305.1 ABC transporter, nucleotide binding/ATPase protein (dipeptide); ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004444306.1 ABC transporter, nucleotide binding/ATPase protein (dipeptide); ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004444307.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004444308.1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily YP_004444309.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004444310.1 LysR substrate binding domain; Transcriptional regulator YP_004444311.1 ABC transporter, substrate binding protein (branched chain amino acid); ABC-type branched-chain amino acid transport systems, periplasmic component YP_004444312.1 ABC transporter, nucleotide binding/ATPase protein (branched chain amino acid); ABC-type branched-chain amino acid transport systems, ATPase component YP_004444313.1 ABC transporter, nucleotide binding/ATPase protein (branched chain amino acid); ABC-type branched-chain amino acid transport systems, ATPase component YP_004444314.1 ABC transporter, membrane spanning protein (branched chain amino acid); Branched-chain amino acid ABC-type transport system, permease components YP_004444315.1 Branched-chain amino acid transport system / permease component; ABC-type branched-chain amino acid transport system, permease component YP_004444316.1 Choline dehydrogenase and related flavoproteins YP_004444317.1 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_004444318.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases YP_004444319.1 3-hydroxybutyrate dehydrogenase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444320.1 Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type DNA-binding domain-containing proteins YP_004444323.1 Quinonprotein alcohol dehydrogenase-like YP_004444324.1 Protein of unknown function DUF892; Uncharacterized protein conserved in bacteria YP_004444325.1 Glycine/D-amino acid oxidases (deaminating) YP_004444326.1 Peptidase C56, PfpI; Putative intracellular protease/amidase YP_004444329.1 N-formylglutamate amidohydrolase YP_004444330.1 Domain of unknown function (DUF1704); Uncharacterized protein conserved in bacteria YP_004444331.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) YP_004444332.1 NAD dependent epimerase/dehydratase family; Nucleoside-diphosphate-sugar epimerases YP_004444333.1 UDP-glucose/GDP-mannose dehydrogenase, dimerisation and substrate-binding; Predicted UDP-glucose 6-dehydrogenase YP_004444334.1 Protein of unknown function DUF6, transmembrane; Permeases of the drug/metabolite transporter (DMT) superfamily YP_004444335.1 Glutathione S-transferase, C-terminal-like; Predicted glutathione S-transferase YP_004444336.1 LysR, substrate-binding; Transcriptional regulator YP_004444337.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004444339.1 ABC transporter, substrate-binding protein, aliphatic sulphonates; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components YP_004444340.1 Binding-protein-dependent transport systems inner membrane component; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_004444341.1 ABC transporter, nucleotide binding/ATPase protein (aliphatic sulfonate); ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_004444342.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; Delta 1-pyrroline-5-carboxylate dehydrogenase YP_004444343.1 Bacterial regulatory proteins, AsnC/Lrp; Transcriptional regulators YP_004444344.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004444346.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; FOG: CheY-like receiver YP_004444347.1 HWE histidine kinase; Signal transduction histidine kinase YP_004444348.1 ATP-binding region, ATPase-like; Signal transduction histidine kinase YP_004444349.1 PRC-barrel domain; Uncharacterized protein containing LysM domain YP_004444350.1 exoB; UDP-glucose 4-epimerase YP_004444353.1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Diaminopimelate decarboxylase YP_004444354.1 Saccharopine dehydrogenase and related proteins YP_004444355.1 DEAD-like helicase, N-terminal; Superfamily II DNA and RNA helicases YP_004444356.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Aspartokinases YP_004444357.1 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) YP_004444358.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is; Protein chain release factor A YP_004444359.1 Modification methylase HemK; Methylase of polypeptide chain release factors YP_004444361.1 ATPase family associated with various cellular activities (AAA); ATPases with chaperone activity, ATP-binding subunit YP_004444362.1 Duplicated hybrid motif; Membrane proteins related to metalloendopeptidases YP_004444364.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; Cell division GTPase YP_004444365.1 Beta-ketoacyl synthase; 3-oxoacyl-(acyl-carrier-protein) synthase YP_004444366.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004444367.1 efflux transporter, RND family, MFP subunit; Membrane-fusion protein YP_004444368.1 AcrB/AcrD/AcrF family; Cation/multidrug efflux pump YP_004444369.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004444370.1 Short-chain dehydrogenases of various substrate specificities YP_004444371.1 NADH:flavin oxidoreductase / NADH oxidase family; NADH:flavin oxidoreductases, Old Yellow Enzyme family YP_004444372.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444373.1 Alcohol dehydrogenase superfamily, zinc-containing; NADPH:quinone reductase and related Zn- dependent oxidoreductases YP_004444374.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004444375.1 Oxidoreductase alpha (molybdopterin) subunit; Anaerobic dehydrogenases, typically selenocysteine-containing YP_004444376.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004444377.1 Aromatic-ring hydroxylase; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_004444378.1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_004444379.1 Zinc finger, UBP-type YP_004444380.1 Response regulator receiver domain; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_004444381.1 Response regulator receiver domain; Response regulator YP_004444382.1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase YP_004444383.1 Cupin, RmlC-type; Thermophilic glucose-6-phosphate isomerase and related metalloenzymes YP_004444384.1 Ferritin/ribonucleotide reductase-like; DNA-binding ferritin-like protein (oxidative damage protectant) YP_004444385.1 alpha/beta hydrolase fold; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004444386.1 LysR, substrate-binding; Transcriptional regulator YP_004444388.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444389.1 Bacterial regulatory protein, MarR; Transcriptional regulators YP_004444390.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004444391.1 Alpha/beta hydrolase fold-1; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004444392.1 ChaC-like protein; Uncharacterized protein involved in cation transport YP_004444393.1 LysR substrate binding domain; Transcriptional regulator YP_004444394.1 Glyoxalase/bleomycin resistance protein/dioxygenase; Lactoylglutathione lyase and related lyases YP_004444395.1 LysR substrate binding domain; Transcriptional regulator YP_004444397.1 Amidases related to nicotinamidase YP_004444398.1 Protein of unknown function DUF1427; Uncharacterized protein conserved in bacteria YP_004444399.1 Metal-dependent hydrolase, composite; Predicted metal-dependent hydrolase with the TIM-barrel fold YP_004444400.1 Surfeit locus 4-related, DoxX; Predicted membrane protein YP_004444401.1 Protein of unknown function DUF894, DitE; Permeases of the major facilitator superfamily YP_004444403.1 [2Fe-2S] binding domain; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs YP_004444404.1 FAD binding domain in molybdopterin dehydrogenase; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs YP_004444405.1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs YP_004444406.1 XdhC and CoxI family; Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family YP_004444407.1 Uncharacterized MobA-related protein YP_004444408.1 Dimeric alpha-beta barrel YP_004444409.1 DJ-1/PfpI family; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_004444410.1 Rtn, c-di-GMP phosphodiesterase class I (EAL domain) YP_004444411.1 Cold-shock protein, DNA-binding; Cold shock proteins YP_004444412.1 glycine betaine/L-proline transport ATP binding subunit; ABC-type proline/glycine betaine transport systems, ATPase components YP_004444413.1 Binding-protein-dependent transport systems inner membrane component; ABC-type proline/glycine betaine transport systems, permease component YP_004444414.1 Binding-protein-dependent transport systems inner membrane component; ABC-type proline/glycine betaine transport system, permease component YP_004444415.1 Substrate-binding region of ABC-type glycine betaine transport system; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) YP_004444416.1 Transcriptional regulators YP_004444418.1 ABC-type phosphate/phosphonate transport system, periplasmic component YP_004444419.1 Fatty acid desaturase, type 1; Fatty acid desaturase YP_004444420.1 Lambda repressor-like, DNA-binding YP_004444421.1 ABC transporter, nucleotide binding/ATPase protein (oligopeptide); ABC-type uncharacterized transport system, duplicated ATPase component YP_004444422.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444423.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444424.1 Bacterial extracellular solute-binding protein, family 5; ABC-type oligopeptide transport system, periplasmic component YP_004444425.1 Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004444426.1 Uncharacterized conserved protein YP_004444427.1 Aldehyde dehydrogenase family; NAD-dependent aldehyde dehydrogenases YP_004444428.1 NAD binding domain of 6-phosphogluconate dehydrogenase; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_004444429.1 LysR substrate binding domain; Transcriptional regulator YP_004444430.1 Peptidase family M20/M25/M40; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004444433.1 GntR, C-terminal; Transcriptional regulators YP_004444434.1 Galactose-binding like YP_004444435.1 Heparinase II/III-like YP_004444436.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004444437.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004444438.1 Six-hairpin glycosidase; Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins YP_004444439.1 ABC transporter related; ABC-type sugar transport systems, ATPase components YP_004444441.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004444442.1 Uncharacterized protein conserved in bacteria YP_004444443.1 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily YP_004444444.1 diguanylate cyclase (GGDEF) domain; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain YP_004444450.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004444451.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004444452.1 ABC transporter related; ABC-type sugar transport systems, ATPase components YP_004444453.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004444454.1 Phosphotriesterase family; Predicted metal-dependent hydrolase with the TIM-barrel fold YP_004444455.1 Protein of unknown function DUF1355; Uncharacterized membrane protein YP_004444456.1 Carbohydrate/purine kinase; Sugar kinases, ribokinase family YP_004444457.1 BtpA family; Predicted TIM-barrel enzyme YP_004444458.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; Acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases YP_004444459.1 Secreted and surface protein containing fasciclin-like repeats YP_004444460.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Aconitase B YP_004444462.1 Asparagine synthase, glutamine-hydrolyzing; Asparagine synthase (glutamine-hydrolyzing) YP_004444463.1 Acyl carrier protein-like YP_004444464.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_004444465.1 NAD synthase YP_004444468.1 sarcosine oxidase, gamma subunit family; Sarcosine oxidase gamma subunit YP_004444469.1 Sarcosine oxidase, alpha subunit, heterotetrameric; Glycine cleavage system T protein (aminomethyltransferase) YP_004444470.1 Sarcosine oxidase, delta subunit, heterotetrameric; Sarcosine oxidase delta subunit YP_004444471.1 Sarcosine oxidase, beta subunit, heterotetrameric; Glycine/D-amino acid oxidases (deaminating) YP_004444472.1 ThiJ/PfpI; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_004444473.1 ABC transporter related; ABC-type sugar transport system, ATPase component YP_004444474.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004444475.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004444476.1 ABC transporter, substrate binding protein (sugar); ABC-type sugar transport system, periplasmic component YP_004444477.1 Bacterial regulatory proteins, gntR family; Transcriptional regulators YP_004444478.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444479.1 Mannitol dehydrogenase, C-terminal; Mannitol-1-phosphate/altronate dehydrogenases YP_004444480.1 D-mannonate dehydratase YP_004444481.1 Aldo/keto reductase; Predicted oxidoreductases (related to aryl- alcohol dehydrogenases) YP_004444482.1 Amidohydrolase 2; Predicted metal-dependent hydrolase of the TIM- barrel fold YP_004444483.1 Major facilitator superfamily MFS-1; Permeases of the major facilitator superfamily YP_004444484.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004444485.1 Alcohol dehydrogenase superfamily, zinc-containing; Threonine dehydrogenase and related Zn- dependent dehydrogenases YP_004444486.1 Helix-turn-helix, AraC type; AraC-type DNA-binding domain-containing proteins YP_004444487.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004444488.1 ABC transporter related; ABC-type sugar transport system, ATPase component YP_004444489.1 Bacterial inner-membrane translocator; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_004444490.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444491.1 FGGY family of carbohydrate kinases, N-terminal domain; Ribulose kinase YP_004444492.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444493.1 General substrate transporter; Permeases of the major facilitator superfamily YP_004444494.1 PRC-barrel-like YP_004444495.1 Inositol monophosphatase family; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004444496.1 Protein-tyrosine phosphatase, Tyr-specific/dual-specificity type; Predicted protein-tyrosine phosphatase YP_004444497.1 Metallophosphoesterasealcineurin- likephosphoesterase; Predicted phosphohydrolases YP_004444498.1 Na+/Pi-cotransporter; Na+/phosphate symporter YP_004444499.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004444500.1 Binding-protein-dependent transport systems inner membrane component; ABC-type Fe3+ transport system, permease component YP_004444501.1 ABC transporter related; ABC-type sugar transport systems, ATPase components YP_004444502.1 ABC transporter periplasmic solute-binding protein; ABC-type Fe3+ transport system, periplasmic component YP_004444503.1 ABC transporter periplasmic solute-binding protein; ABC-type Fe3+ transport system, periplasmic component YP_004444504.1 ABC transporter periplasmic solute-binding protein; ABC-type Fe3+ transport system, periplasmic component YP_004444505.1 Inositol monophosphatase family; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004444506.1 Protein-tyrosine phosphatase, dual specificity; Predicted protein-tyrosine phosphatase YP_004444507.1 Integral membrane protein TerC family; Membrane protein TerC, possibly involved in tellurium resistance YP_004444508.1 Protein of unknown function DUF1402 YP_004444509.1 Predicted transglutaminase-like cysteine peptidase, BTLCP, Bacterial protein of unknown function (DUF920); Predicted transglutaminase-like cysteine proteinase YP_004444510.1 ABC transporter related; ABC-type sugar transport systems, ATPase components YP_004444511.1 Binding-protein-dependent transport system inner membrane component; ABC-type sugar transport system, permease component YP_004444512.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004444513.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004444514.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004444515.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004444516.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004444518.1 ThiJ/PfpI; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_004444519.1 Sarcosine oxidase, beta subunit, heterotetrameric; Glycine/D-amino acid oxidases (deaminating) YP_004444520.1 Sarcosine oxidase, delta subunit, heterotetrameric; Sarcosine oxidase delta subunit YP_004444521.1 Sarcosine oxidase, alpha subunit, heterotetrameric; Glycine cleavage system T protein (aminomethyltransferase) YP_004444522.1 Sarcosine oxidase, gamma subunit, heterotetrameric; Sarcosine oxidase gamma subunit YP_004444523.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Glycine/serine hydroxymethyltransferase YP_004444524.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; Formyltetrahydrofolate hydrolase YP_004444525.1 MscS Mechanosensitive ion channel; Small-conductance mechanosensitive channel YP_004444526.1 putative ParB-like nuclease; Uncharacterized protein conserved in bacteria YP_004444527.1 Sulphate transporter; Sulfate permease and related transporters (MFS superfamily) YP_004444528.1 Cupin, RmlC-type; Uncharacterized conserved protein, contains double-stranded beta-helix domain YP_004444529.1 Protein of unknown function DUF839, bacterial; Predicted phosphatase YP_004444530.1 4'-phosphopantetheinyl transferase, iron uptake/ Agrobactin biosynthesis; Phosphopantetheinyl transferase component of siderophore synthetase YP_004444531.1 Short-chain dehydrogenase/reductase SDR, iron uptake/ Agrobactin biosynthesis; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444532.1 Isochorismatase hydrolase; Isochorismate hydrolase YP_004444533.1 2,3-dihydroxybenzoate-AMP ligase; Peptide arylation enzymes YP_004444534.1 probable isochorismate synthase; Isochorismate synthase YP_004444535.1 Non-ribosomal peptide synthetase modules and related proteins YP_004444536.1 Condensation domain; Non-ribosomal peptide synthetase modules and related proteins YP_004444537.1 Condensation domain; Non-ribosomal peptide synthetase modules and related proteins YP_004444538.1 probable 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochorismatase protein YP_004444539.1 Siderophore-interacting FAD-binding domain YP_004444540.1 Periplasmic binding protein; ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_004444541.1 Bacterial transport system permease protein; ABC-type Fe3+-siderophore transport system, permease component YP_004444542.1 Bacterial transport system permease protein; ABC-type Fe3+-siderophore transport system, permease component YP_004444543.1 ABC transporter related; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components YP_004444544.1 Bacterial luciferase-like; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin- dependent oxidoreductases YP_004444545.1 Transcriptional regulator IclR, C-terminal; Transcriptional regulator YP_004444546.1 TonB-dependent receptor, beta-barrel; Outer membrane receptor proteins, mostly Fe transport YP_004444547.1 Acyl-CoA dehydrogenase/oxidase, middle and N-terminal; Acyl-CoA dehydrogenases YP_004444548.1 LysR substrate binding domain; Transcriptional regulator YP_004444549.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004444550.1 Bacterial extracellular solute-binding protein, family 1; Spermidine/putrescine-binding periplasmic protein YP_004444551.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component I YP_004444552.1 Binding-protein-dependent transport systems inner membrane component; ABC-type spermidine/putrescine transport system, permease component II YP_004444553.1 ABC transporter related; ABC-type spermidine/putrescine transport systems, ATPase components YP_004444554.1 Inosine/uridine-preferring nucleoside hydrolase; Inosine-uridine nucleoside N-ribohydrolase YP_004444555.1 Amidohydrolase family YP_004444556.1 Permeases of the major facilitator superfamily YP_004444557.1 Peptidase family M20/M25/M40; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004444558.1 Involved in nucleotide synthesis and salvage; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins YP_004444559.1 Peptidase M19, renal dipeptidase; Zn-dependent dipeptidase, microsomal dipeptidase homolog YP_004444560.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004444561.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444562.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444563.1 ABC transporter related; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component YP_004444564.1 ABC transporter related; ABC-type oligopeptide transport system, ATPase component YP_004444565.1 LysR, substrate-binding; Transcriptional regulator YP_004444566.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004444567.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444568.1 ABC transporter, membrane spanning protein (oligopeptide); ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444569.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases YP_004444570.1 Peptidase C56, PfpI; Putative intracellular protease/amidase YP_004444571.1 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis YP_004444572.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444573.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444574.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004444575.1 Peptidase family M20/M25/M40; Metal-dependentamidase/aminoacylase/carboxypeptidase YP_004444576.1 ABC transporter related; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004444577.1 putative sugar-binding region; Transcriptional regulator, contains sigma factor-related N-terminal domain YP_004444578.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004444579.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004444580.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004444581.1 ABC transporter related; ABC-type sugar transport systems, ATPase components YP_004444582.1 Mannitol dehydrogenase C-terminal domain; Mannitol-1-phosphate/altronate dehydrogenases YP_004444583.1 Haloacid dehalogenase-like hydrolase; Predicted phosphatase/phosphohexomutase YP_004444584.1 FGGY family of carbohydrate kinases, N-terminal domain; Ribulose kinase YP_004444585.1 Helix-turn-helix protein RpiR; Transcriptional regulators YP_004444586.1 putative role in sulfur assimilation; Uncharacterized protein involved in cysteine biosynthesis YP_004444587.1 HhH-GPD superfamily base excision DNA repair protein; Predicted EndoIII-related endonuclease YP_004444588.1 Integral membrane protein YP_004444589.1 6-O-methylguanine DNA methyltransferase, DNA binding domain; Methylated DNA-protein cysteine methyltransferase YP_004444590.1 putative sugar-binding region; Transcriptional regulator, contains sigma factor-related N-terminal domain YP_004444591.1 Transaldolase AB; Transaldolase YP_004444592.1 Transcriptional regulator IclR, C-terminal; Transcriptional regulator YP_004444593.1 Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444594.1 Protein of unknown function DUF1328 YP_004444595.1 ABC 3 transport family; ABC-type Mn2+/Zn2+ transport systems, permease components YP_004444596.1 ABC 3 transport family; ABC-type Mn2+/Zn2+ transport systems, permease components YP_004444597.1 ABC transporter related; ABC-type Mn/Zn transport systems, ATPase component YP_004444598.1 Periplasmic solute binding protein family; ABC-type metal ion transport system, periplasmic component/surface adhesin YP_004444600.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Lysyl-tRNA synthetase (class II) YP_004444601.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; Glutamyl- and glutaminyl-tRNA synthetases YP_004444602.1 Divalent ion symporter; Di- and tricarboxylate transporters YP_004444603.1 Integral membrane protein TerC family; Membrane protein TerC, possibly involved in tellurium resistance YP_004444604.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004444605.1 Secretion protein HlyD YP_004444606.1 Major facilitator superfamily; Permeases of the major facilitator superfamily YP_004444607.1 Bacterial regulatory protein, LacI; ABC-type sugar transport system, periplasmic component YP_004444608.1 FGGY family of carbohydrate kinases, N-terminal domain; Sugar (pentulose and hexulose) kinases YP_004444609.1 Xylose isomerase-like, TIM barrel YP_004444611.1 Glycoside hydrolase, family 1; Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase YP_004444612.1 Nitroreductase family YP_004444613.1 ABC transporter related; ABC-type metal ion transport system, ATPase component YP_004444614.1 Binding-protein-dependent transport systems inner membrane component; ABC-type metal ion transport system, permease component YP_004444615.1 Lipoprotein YaeC; ABC-type metal ion transport system, periplasmic component/surface antigen YP_004444616.1 diguanylate cyclase (GGDEF) domain; c-di-GMP phosphodiesterase class I (EAL domain) YP_004444617.1 Rhodanese-like domain; Predicted sulfurtransferase YP_004444618.1 CHAD domain; Uncharacterized conserved protein YP_004444619.1 Uncharacterised conserved protein UCP016487, CYTH region; Uncharacterized protein conserved in bacteria YP_004444620.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; 2-keto-3-deoxy-6-phosphogluconate aldolase YP_004444621.1 Protein of unknown function DUF533; Uncharacterized protein conserved in bacteria YP_004444622.1 GCN5-related N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004444624.1 Nickel/cobalt transporter, high-affinity; ABC-type uncharacterized transport system, permease component YP_004444625.1 Protein of unknown function DUF1007; ABC-type uncharacterized transport system, periplasmic component YP_004444628.1 Outer membrane protein, beta-barrel; Opacity protein and related surface antigens YP_004444629.1 Major facilitator superfamily MFS-1; Permeases of the major facilitator superfamily YP_004444630.1 WD40 repeat-like; FOG: WD40 repeat YP_004444631.1 Cobalamin (vitamin B12) biosynthesis CobW-like; Putative GTPases (G3E family) YP_004444632.1 Creatininase; Uncharacterized protein, putative amidase YP_004444633.1 transcriptional regulator, MarR family; Transcriptional regulators YP_004444634.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004444636.1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Lactate dehydrogenase and related dehydrogenases YP_004444637.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004444638.1 Myo-inositol catabolism protein IolB; Uncharacterized enzyme involved in inositol metabolism YP_004444639.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004444640.1 Thiamine pyrophosphate enzyme, N-terminal TPP binding region YP_004444641.1 Carbohydrate/purine kinase; Uncharacterized protein conserved in bacteria YP_004444642.1 Sugar isomerase (SIS); Transcriptional regulators YP_004444643.1 ABC transporter, nucleotide binding/ATPase protein (branched chain amino acid); ABC-type branched-chain amino acid transport systems, ATPase component YP_004444644.1 ABC transporter, nucleotide binding/ATPase protein (branched chain amino acid); ABC-type branched-chain amino acid transport systems, ATPase component YP_004444645.1 Branched-chain amino acid transport system / permease component; ABC-type branched-chain amino acid transport system, permease component YP_004444646.1 Branched-chain amino acid transport system / permease component; Branched-chain amino acid ABC-type transport system, permease components YP_004444647.1 Extracellular ligand-binding receptor; ABC-type branched-chain amino acid transport systems, periplasmic component YP_004444650.1 Peptidase M14, carboxypeptidase A YP_004444651.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444652.1 Binding-protein-dependent transport systems inner membrane component; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_004444653.1 Bacterial extracellular solute-binding protein, family 5; ABC-type dipeptide transport system, periplasmic component YP_004444654.1 ABC transporter, nucleotide binding/ATPase protein; ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_004444656.1 Dimeric alpha-beta barrel; Uncharacterized conserved protein YP_004444657.1 Xylose isomerase-like, TIM barrel; 4-hydroxyphenylpyruvate dioxygenase and related hemolysins YP_004444658.1 Bacterial regulatory proteins, tetR family; Transcriptional regulator YP_004444659.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase II YP_004444660.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_004444661.1 ABC transporter, nucleotide binding/ATPase protein (amino acid); ABC-type polar amino acid transport system, ATPase component YP_004444662.1 Bacterial extracellular solute-binding proteins, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004444663.1 Bacterial extracellular solute-binding proteins, family 3; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_004444664.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004444665.1 Binding-protein-dependent transport systems inner membrane component; ABC-type amino acid transport system, permease component YP_004444666.1 Catalyzes the cycloisomerization of cis,cis-muconate; Adenylosuccinate lyase YP_004444667.1 Intradiol ring-cleavage dioxygenase, core; Protocatechuate 3,4-dioxygenase beta subunit YP_004444668.1 Intradiol ring-cleavage dioxygenase, core; Protocatechuate 3,4-dioxygenase beta subunit YP_004444669.1 Carboxymuconolactone decarboxylase family; Uncharacterized homolog of gamma- carboxymuconolactone decarboxylase subunit YP_004444670.1 alpha/beta hydrolase fold; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_004444671.1 pca operon transcription factor PcaQ; Transcriptional regulator YP_004444672.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_004444673.1 AraC protein, arabinose-binding/dimerisation; AraC-type DNA-binding domain-containing proteins YP_004444674.1 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR; Transcriptional regulator YP_004444675.1 Coenzyme A transferase; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit YP_004444676.1 Coenzyme A transferase; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit YP_004444677.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Acetyl-CoA acetyltransferase YP_004444678.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004444679.1 Periplasmic binding protein/LacI transcriptional regulator; ABC-type sugar transport system, periplasmic component YP_004444680.1 Xylose isomerase-like, TIM barrel; Sugar phosphate isomerases/epimerases YP_004444681.1 Oxidoreductase family, NAD-binding Rossmann fold; Predicted dehydrogenases and related proteins YP_004444682.1 Uncharacterised conserved protein, sugar epimerase region; Predicted sugar epimerase YP_004444683.1 Periplasmic binding protein/LacI transcriptional regulator; Transcriptional regulators YP_004444684.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004444685.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004444686.1 ABC transporter, nucleotide binding/ATPase protein (sugar); ABC-type sugar transport systems, ATPase components YP_004444687.1 Pectin lyase fold/virulence factor; Endopolygalacturonase YP_004444688.1 Glycosyl Hydrolase Family 88; Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins YP_004444690.1 Bacterial extracellular solute-binding protein, family 1; ABC-type sugar transport system, periplasmic component YP_004444691.1 Pectin lyase fold/virulence factor; Membrane-associated phospholipid phosphatase YP_004444692.1 ROK; Transcriptional regulator/sugar kinase YP_004444693.1 Bacterial extracellular solute-binding protein, family 1; ABC-type uncharacterized transport system, periplasmic component YP_004444694.1 ABC transporter, nucleotide binding/ATPase protein; ABC-type sugar transport systems, ATPase components YP_004444695.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport systems, permease components YP_004444696.1 Binding-protein-dependent transport systems inner membrane component; ABC-type sugar transport system, permease component YP_004444698.1 Inositol monophosphatase family; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_004444699.1 ROK; Transcriptional regulator/sugar kinase YP_004444700.1 Bacterial extracellular solute-binding protein, family 1; ABC-type Fe3+ transport system, periplasmic component YP_004444701.1 ABC transporter, nucleotide binding/ATPase protein; ABC-type spermidine/putrescine transport systems, ATPase components YP_004444702.1 Binding-protein-dependent transport systems inner membrane component; ABC-type Fe3+ transport system, permease component YP_004444704.1 FMN-binding split barrel; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_004444705.1 4Fe-4S ferredoxin, iron-sulphur binding YP_004444706.1 Manganese and iron superoxide dismutase YP_004444707.1 Homeodomain-like; Transcriptional regulator YP_004444708.1 Bacterial bifunctional deaminase-reductase, C-terminal; Dihydrofolate reductase YP_004444709.1 Linear amide C-N hydrolases, choloylglycine hydrolase family; Penicillin V acylase and related amidases YP_004444711.1 Hemolysin activator HlyB; Hemolysin activation/secretion protein YP_004444713.1 haemagglutination activity domain; Large exoproteins involved in heme utilization or adhesion YP_004444716.1 Transposase IS3/IS911; Transposase and inactivated derivatives YP_004444717.1 Transposase and inactivated derivatives YP_004444718.1 Transposase IS116/IS110/IS902 family; Transposase and inactivated derivatives YP_004444719.1 Integrase, catalytic core; Transposase and inactivated derivatives YP_004444720.1 Transposase, IS111A/IS1328/IS1533; Transposase and inactivated derivatives YP_004444721.1 Integrase, catalytic core; Transposase and inactivated derivatives YP_004444722.1 Transposase IS3/IS911; Transposase and inactivated derivatives YP_004444725.1 HEPN; Predicted nucleotidyltransferases YP_004444731.1 Protein of unknown function DUF1452; Predicted small integral membrane protein YP_004444732.1 Multimeric flavodoxin WrbA YP_004444736.1 Protein of unknown function DUF892; Uncharacterized protein conserved in bacteria YP_004444738.1 Amidases related to nicotinamidase YP_004444742.1 RNA polymerase sigma-70; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_004444743.1 Malto-oligosyltrehalose trehalohydrolase; 1,4-alpha-glucan branching enzyme YP_004444744.1 Glycogen/starch synthases, ADP-glucose type YP_004444746.1 Cyclic nucleotide-binding; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_004444750.1 RmlC-like jelly roll fold; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_004444751.1 Helix-turn-helix, Fis-type YP_004444757.1 Methyltransferase type 11; SAM-dependent methyltransferases YP_004444758.1 Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylate cyclase, family 3 (some proteins contain HAMP domain) YP_004444759.1 GCN5-related N-acetyltransferase; Acetyltransferases, including N-acetylases of ribosomal proteins YP_004444760.1 Beta-lactamase-type transpeptidase fold; Beta-lactamase class C and other penicillin binding proteins YP_004444761.1 Major facilitator superfamily; Arabinose efflux permease YP_004444762.1 LysR substrate binding domain; Transcriptional regulator YP_004444763.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_004444764.1 two component, sigma54 specific, transcriptional regulator, Fis family; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains YP_004444766.1 Porin, alpha proteobacteria type; Opacity protein and related surface antigens YP_004444767.1 Protein of unknown function DUF1486; Predicted ester cyclase YP_004444768.1 Phosphoglycerate mutase family; Phosphoglycerate mutase 1 YP_004444773.1 Lambda repressor-like, DNA-binding; Predicted transcriptional regulators YP_004444774.1 HipA-like C-terminal domain; Uncharacterized protein related to capsule biosynthesis enzymes YP_004444776.1 Winged helix repressor DNA-binding; DNA-binding HTH domain-containing proteins YP_004444780.1 HipA-like C-terminal domain; Uncharacterized protein related to capsule biosynthesis enzymes