-- dump date 20140618_204508 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_212986.1 15605613 1192533 1..2100 1 NC_000918.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2100 fusA 1192533 fusA Aquifex aeolicus VF5 elongation factor G NP_212986.1 1 D 224324 CDS NP_212987.1 15605614 1192534 2117..3334 1 NC_000918.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3334 tufA1 1192534 tufA1 Aquifex aeolicus VF5 elongation factor Tu NP_212987.1 2117 D 224324 CDS NP_212988.1 15605615 1192535 3346..3660 1 NC_000918.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3660 rpsJ 1192535 rpsJ Aquifex aeolicus VF5 30S ribosomal protein S10 NP_212988.1 3346 D 224324 CDS NP_212989.1 15605616 1192536 3665..4390 1 NC_000918.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 4390 rplC 1192536 rplC Aquifex aeolicus VF5 50S ribosomal protein L3 NP_212989.1 3665 D 224324 CDS NP_212990.1 15605617 1192537 4387..4986 1 NC_000918.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 4986 rplD 1192537 rplD Aquifex aeolicus VF5 50S ribosomal protein L4 NP_212990.1 4387 D 224324 CDS NP_212991.1 15605618 1192538 4990..5301 1 NC_000918.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 5301 rplW 1192538 rplW Aquifex aeolicus VF5 50S ribosomal protein L23 NP_212991.1 4990 D 224324 CDS NP_212992.1 15605619 1192539 5313..6227 1 NC_000918.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 6227 rplB 1192539 rplB Aquifex aeolicus VF5 50S ribosomal protein L2 NP_212992.1 5313 D 224324 CDS NP_212993.1 15605620 1192540 6340..6900 1 NC_000918.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 6900 rpsS 1192540 rpsS Aquifex aeolicus VF5 30S ribosomal protein S19 NP_212993.1 6340 D 224324 CDS NP_212994.1 15605621 1192541 7018..7314 1 NC_000918.1 50S ribosomal protein L22 7314 rplV 1192541 rplV Aquifex aeolicus VF5 50S ribosomal protein L22 NP_212994.1 7018 D 224324 CDS NP_212995.1 15605622 1192634 7317..7955 1 NC_000918.1 30S ribosomal protein S3 7955 rpsC 1192634 rpsC Aquifex aeolicus VF5 30S ribosomal protein S3 NP_212995.1 7317 D 224324 CDS NP_212996.1 15605623 1192635 8017..8445 1 NC_000918.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 8445 rplP 1192635 rplP Aquifex aeolicus VF5 50S ribosomal protein L16 NP_212996.1 8017 D 224324 CDS NP_212997.1 15607133 1193996 8457..8678 1 NC_000918.1 50S ribosomal protein L29 8678 rpmC 1193996 rpmC Aquifex aeolicus VF5 50S ribosomal protein L29 NP_212997.1 8457 D 224324 CDS NP_212998.1 15605624 1192636 8678..9001 1 NC_000918.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 9001 rpsQ 1192636 rpsQ Aquifex aeolicus VF5 30S ribosomal protein S17 NP_212998.1 8678 D 224324 CDS NP_212999.1 15605625 1192637 9001..9660 1 NC_000918.1 3-dehydroquinate dehydratase 9660 aroD 1192637 aroD Aquifex aeolicus VF5 3-dehydroquinate dehydratase NP_212999.1 9001 D 224324 CDS NP_213000.1 15605626 1192638 complement(9657..10157) 1 NC_000918.1 hypothetical protein 10157 1192638 aq_022 Aquifex aeolicus VF5 hypothetical protein NP_213000.1 9657 R 224324 CDS NP_213001.1 15605627 1192639 complement(10169..11299) 1 NC_000918.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 11299 argD 1192639 argD Aquifex aeolicus VF5 acetylornithine aminotransferase NP_213001.1 10169 R 224324 CDS NP_213002.1 15605628 1192640 complement(11296..12609) 1 NC_000918.1 nucleotide sugar dehydrogenase 12609 nsd 1192640 nsd Aquifex aeolicus VF5 nucleotide sugar dehydrogenase NP_213002.1 11296 R 224324 CDS NP_213003.1 15605629 1192641 complement(12887..14005) 1 NC_000918.1 rod shape determining protein RodA 14005 rodA 1192641 rodA Aquifex aeolicus VF5 rod shape determining protein RodA NP_213003.1 12887 R 224324 CDS NP_213004.1 15607137 1194005 complement(13974..14183) 1 NC_000918.1 thiamine biosynthesis sulfur transfer protein 14183 thiS 1194005 thiS Aquifex aeolicus VF5 thiamine biosynthesis sulfur transfer protein NP_213004.1 13974 R 224324 CDS NP_213005.1 15605630 1192642 complement(14174..14656) 1 NC_000918.1 hypothetical protein 14656 1192642 aq_026 Aquifex aeolicus VF5 hypothetical protein NP_213005.1 14174 R 224324 CDS NP_213006.1 15605631 1192643 complement(14676..16454) 1 NC_000918.1 hypothetical protein 16454 1192643 aq_027 Aquifex aeolicus VF5 hypothetical protein NP_213006.1 14676 R 224324 CDS NP_213007.1 15605632 1192644 complement(16527..17006) 1 NC_000918.1 hypothetical protein 17006 1192644 aq_028 Aquifex aeolicus VF5 hypothetical protein NP_213007.1 16527 R 224324 CDS NP_213008.1 15605633 1192645 17053..18261 1 NC_000918.1 molybdenum cofactor biosynthesis protein A 18261 moeA1 1192645 moeA1 Aquifex aeolicus VF5 molybdenum cofactor biosynthesis protein A NP_213008.1 17053 D 224324 CDS NP_213009.1 15605634 1192646 18275..19615 1 NC_000918.1 transporter 19615 trnS 1192646 trnS Aquifex aeolicus VF5 transporter NP_213009.1 18275 D 224324 CDS NP_213010.1 15605635 1192647 19620..21062 1 NC_000918.1 hypothetical protein 21062 1192647 aq_032 Aquifex aeolicus VF5 hypothetical protein NP_213010.1 19620 D 224324 CDS NP_213011.1 15605636 1192648 complement(21051..22346) 1 NC_000918.1 hypothetical protein 22346 1192648 aq_035 Aquifex aeolicus VF5 hypothetical protein NP_213011.1 21051 R 224324 CDS NP_213012.1 15605637 1192649 22379..22885 1 NC_000918.1 hypothetical protein 22885 1192649 aq_036 Aquifex aeolicus VF5 hypothetical protein NP_213012.1 22379 D 224324 CDS NP_213013.1 15605638 1192650 22998..23525 1 NC_000918.1 hypothetical protein 23525 1192650 aq_037 Aquifex aeolicus VF5 hypothetical protein NP_213013.1 22998 D 224324 CDS NP_213014.1 15605639 1192651 23541..24407 1 NC_000918.1 3-hydroxyisobutyrate dehydrogenase 24407 hibD 1192651 hibD Aquifex aeolicus VF5 3-hydroxyisobutyrate dehydrogenase NP_213014.1 23541 D 224324 CDS NP_213015.1 15605640 1192652 complement(24404..24982) 1 NC_000918.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 24982 hisB 1192652 hisB Aquifex aeolicus VF5 imidazoleglycerol-phosphate dehydratase NP_213015.1 24404 R 224324 CDS NP_213016.1 15605641 1192653 complement(24997..26217) 1 NC_000918.1 hypothetical protein 26217 1192653 aq_040 Aquifex aeolicus VF5 hypothetical protein NP_213016.1 24997 R 224324 CDS NP_213017.1 15605642 1192654 complement(26274..26585) 1 NC_000918.1 hypothetical protein 26585 1192654 aq_041 Aquifex aeolicus VF5 hypothetical protein NP_213017.1 26274 R 224324 CDS NP_213018.1 15605643 1192655 complement(26618..27340) 1 NC_000918.1 cytochrome C 27340 cyc 1192655 cyc Aquifex aeolicus VF5 cytochrome C NP_213018.1 26618 R 224324 CDS NP_213019.1 15605644 1192656 complement(27337..28566) 1 NC_000918.1 cytochrome b 28566 petB 1192656 petB Aquifex aeolicus VF5 cytochrome b NP_213019.1 27337 R 224324 CDS NP_213020.1 15605645 1192657 complement(28580..29125) 1 NC_000918.1 Rieske-I iron sulfur protein 29125 petA 1192657 petA Aquifex aeolicus VF5 Rieske-I iron sulfur protein NP_213020.1 28580 R 224324 CDS NP_213021.1 15605646 1192658 29251..30171 1 NC_000918.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 30171 pyrD 1192658 pyrD Aquifex aeolicus VF5 dihydroorotate dehydrogenase 1B NP_213021.1 29251 D 224324 CDS NP_213022.1 15605647 1192659 30179..30478 1 NC_000918.1 pterin-4a-carbinolamine dehydratase 30478 phhB 1192659 phhB Aquifex aeolicus VF5 pterin-4a-carbinolamine dehydratase NP_213022.1 30179 D 224324 CDS NP_213023.1 15605648 1192660 30475..33036 1 NC_000918.1 hypothetical protein 33036 1192660 aq_050 Aquifex aeolicus VF5 hypothetical protein NP_213023.1 30475 D 224324 CDS NP_213024.1 15605649 1192661 complement(33033..33887) 1 NC_000918.1 4-hydroxybenzoate octaprenyltransferase 33887 ubiA 1192661 ubiA Aquifex aeolicus VF5 4-hydroxybenzoate octaprenyltransferase NP_213024.1 33033 R 224324 CDS NP_213025.1 15605650 1192662 complement(33884..34963) 1 NC_000918.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 34963 mraY 1192662 mraY Aquifex aeolicus VF5 phospho-N-acetylmuramoyl-pentapeptide- transferase NP_213025.1 33884 R 224324 CDS NP_213026.1 15605651 1192663 complement(34963..35580) 1 NC_000918.1 hypothetical protein 35580 1192663 aq_054 Aquifex aeolicus VF5 hypothetical protein NP_213026.1 34963 R 224324 CDS NP_213027.1 15605652 1192664 35564..36322 1 NC_000918.1 cytochrome C biogenesis protein 36322 hemX1 1192664 hemX1 Aquifex aeolicus VF5 cytochrome C biogenesis protein NP_213027.1 35564 D 224324 CDS NP_213028.1 15605653 1192481 complement(36306..36758) 1 NC_000918.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 36758 fabZ 1192481 fabZ Aquifex aeolicus VF5 (3R)-hydroxymyristoyl-ACP dehydratase NP_213028.1 36306 R 224324 CDS NP_213029.1 15605654 1192482 36782..37426 1 NC_000918.1 sugar fermentation stimulation protein 37426 sfsA 1192482 sfsA Aquifex aeolicus VF5 sugar fermentation stimulation protein NP_213029.1 36782 D 224324 CDS NP_213030.1 15605655 1192483 37923..38273 1 NC_000918.1 hypothetical protein 38273 1192483 aq_058 Aquifex aeolicus VF5 hypothetical protein NP_213030.1 37923 D 224324 CDS NP_213032.1 15605657 1192485 complement(38923..39459) 1 NC_000918.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 39459 mogA 1192485 mogA Aquifex aeolicus VF5 molybdenum cofactor biosynthesis protein MogA NP_213032.1 38923 R 224324 CDS NP_213033.1 15605658 1192486 39496..40338 1 NC_000918.1 spermidine synthase 40338 speE 1192486 speE Aquifex aeolicus VF5 spermidine synthase NP_213033.1 39496 D 224324 CDS NP_213034.1 15605659 1192487 40413..40745 1 NC_000918.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 40745 rpsF 1192487 rpsF Aquifex aeolicus VF5 30S ribosomal protein S6 NP_213034.1 40413 D 224324 CDS NP_213035.1 15605660 1192488 40735..41178 1 NC_000918.1 single stranded DNA-binding protein 41178 ssb 1192488 ssb Aquifex aeolicus VF5 single stranded DNA-binding protein NP_213035.1 40735 D 224324 CDS NP_213036.1 15605661 1192489 41197..41415 1 NC_000918.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 41415 rpsR 1192489 rpsR Aquifex aeolicus VF5 30S ribosomal protein S18 NP_213036.1 41197 D 224324 CDS NP_213037.1 15605662 1192490 41470..41649 1 NC_000918.1 hypothetical protein 41649 1192490 aq_064b Aquifex aeolicus VF5 hypothetical protein NP_213037.1 41470 D 224324 CDS NP_213038.1 15605663 1192491 41650..41883 1 NC_000918.1 hypothetical protein 41883 1192491 aq_064c Aquifex aeolicus VF5 hypothetical protein NP_213038.1 41650 D 224324 CDS NP_213039.1 15605664 1192492 complement(41880..42773) 1 NC_000918.1 hypothetical protein 42773 1192492 aq_065 Aquifex aeolicus VF5 hypothetical protein NP_213039.1 41880 R 224324 CDS NP_213040.1 15605665 1192493 42795..43763 1 NC_000918.1 hypothetical protein 43763 1192493 aq_066 Aquifex aeolicus VF5 hypothetical protein NP_213040.1 42795 D 224324 CDS NP_213041.1 15605666 1192494 complement(43756..44268) 1 NC_000918.1 dimethylsulfoxide reductase subunit B 44268 dmsB2 1192494 dmsB2 Aquifex aeolicus VF5 dimethylsulfoxide reductase subunit B NP_213041.1 43756 R 224324 CDS NP_213042.1 15605667 1192495 complement(44501..44857) 1 NC_000918.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 44857 rplQ 1192495 rplQ Aquifex aeolicus VF5 50S ribosomal protein L17 NP_213042.1 44501 R 224324 CDS NP_213043.1 15605668 1192496 complement(44863..45816) 1 NC_000918.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 45816 rpoA 1192496 rpoA Aquifex aeolicus VF5 DNA-directed RNA polymerase subunit alpha NP_213043.1 44863 R 224324 CDS NP_213044.1 15605669 1192497 complement(45829..46464) 1 NC_000918.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 46464 rpsD 1192497 rpsD Aquifex aeolicus VF5 30S ribosomal protein S4 NP_213044.1 45829 R 224324 CDS NP_213045.1 15605670 1192498 complement(46465..46842) 1 NC_000918.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 46842 rpsK 1192498 rpsK Aquifex aeolicus VF5 30S ribosomal protein S11 NP_213045.1 46465 R 224324 CDS NP_213046.1 15605671 1192499 complement(46858..47238) 1 NC_000918.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 47238 rpsM 1192499 rpsM Aquifex aeolicus VF5 30S ribosomal protein S13 NP_213046.1 46858 R 224324 CDS NP_213047.1 15605672 1192500 complement(47216..47365) 1 NC_000918.1 50S ribosomal protein L36 47365 rpmJ 1192500 rpmJ Aquifex aeolicus VF5 50S ribosomal protein L36 NP_213047.1 47216 R 224324 CDS NP_213048.1 15605673 1192501 complement(47426..47668) 1 NC_000918.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 47668 infA 1192501 infA Aquifex aeolicus VF5 translation initiation factor IF-1 NP_213048.1 47426 R 224324 CDS NP_213049.1 15605674 1192502 complement(47671..48447) 1 NC_000918.1 methionyl aminopeptidase 48447 map 1192502 map Aquifex aeolicus VF5 methionyl aminopeptidase NP_213049.1 47671 R 224324 CDS NP_213050.1 15605675 1192503 complement(48437..49057) 1 NC_000918.1 adenylate kinase 49057 kad 1192503 kad Aquifex aeolicus VF5 adenylate kinase NP_213050.1 48437 R 224324 CDS NP_213051.1 15605676 1192504 complement(49062..50351) 1 NC_000918.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 50351 secY 1192504 secY Aquifex aeolicus VF5 preprotein translocase subunit SecY NP_213051.1 49062 R 224324 CDS NP_213052.1 15605677 1192505 50396..50605 1 NC_000918.1 50S ribosomal protein L28 50605 rpmB 1192505 rpmB Aquifex aeolicus VF5 50S ribosomal protein L28 NP_213052.1 50396 D 224324 CDS NP_213053.1 15605678 1192506 50605..51801 1 NC_000918.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 51801 aroC 1192506 aroC Aquifex aeolicus VF5 chorismate synthase NP_213053.1 50605 D 224324 CDS NP_213054.1 15605679 1192507 51803..52405 1 NC_000918.1 hypothetical protein 52405 1192507 aq_082 Aquifex aeolicus VF5 hypothetical protein NP_213054.1 51803 D 224324 CDS NP_213055.1 15605680 1192508 complement(52390..53406) 1 NC_000918.1 hypothetical protein 53406 1192508 aq_083 Aquifex aeolicus VF5 hypothetical protein NP_213055.1 52390 R 224324 CDS NP_213056.1 15605681 1192509 53671..54474 1 NC_000918.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 54474 kdsA 1192509 kdsA Aquifex aeolicus VF5 2-dehydro-3-deoxyphosphooctonate aldolase NP_213056.1 53671 D 224324 CDS NP_213057.1 15605682 1192510 54471..55133 1 NC_000918.1 molybdenum ABC transporter permease 55133 modC 1192510 modC Aquifex aeolicus VF5 molybdenum ABC transporter permease NP_213057.1 54471 D 224324 CDS NP_213058.1 15605683 1192511 55256..55597 1 NC_000918.1 hypothetical protein 55597 1192511 aq_087 Aquifex aeolicus VF5 hypothetical protein NP_213058.1 55256 D 224324 CDS NP_213059.1 15605684 1192512 55612..55947 1 NC_000918.1 hypothetical protein 55947 1192512 aq_088 Aquifex aeolicus VF5 hypothetical protein NP_213059.1 55612 D 224324 CDS NP_213060.1 15605685 1192513 55975..56379 1 NC_000918.1 hypothetical protein 56379 1192513 aq_090 Aquifex aeolicus VF5 hypothetical protein NP_213060.1 55975 D 224324 CDS NP_213061.1 15607134 1193997 56372..57964 1 NC_000918.1 ATPase AAA 57964 1193997 aq_091m Aquifex aeolicus VF5 ATPase AAA NP_213061.1 56372 D 224324 CDS NP_213062.1 15605686 1192514 complement(57961..60366) 1 NC_000918.1 ribonucleotide reductase subunit alpha 60366 nrdA 1192514 nrdA Aquifex aeolicus VF5 ribonucleotide reductase subunit alpha NP_213062.1 57961 R 224324 CDS NP_213063.1 15605687 1192515 complement(60452..61675) 1 NC_000918.1 hypothetical protein 61675 1192515 aq_097 Aquifex aeolicus VF5 hypothetical protein NP_213063.1 60452 R 224324 CDS NP_213064.1 15605688 1192516 61696..61998 1 NC_000918.1 protein export membrane protein SecG 61998 secG 1192516 secG Aquifex aeolicus VF5 protein export membrane protein SecG NP_213064.1 61696 D 224324 CDS NP_213065.1 15605689 1192517 61934..62779 1 NC_000918.1 protoporphyrinogen oxidase 62779 hemK 1192517 hemK Aquifex aeolicus VF5 protoporphyrinogen oxidase NP_213065.1 61934 D 224324 CDS NP_213066.1 15605690 1192518 62770..64020 1 NC_000918.1 hemolysin 64020 hly3 1192518 hly3 Aquifex aeolicus VF5 hemolysin NP_213066.1 62770 D 224324 CDS NP_213067.1 15605691 1192519 complement(63986..64726) 1 NC_000918.1 hypothetical protein 64726 1192519 aq_103 Aquifex aeolicus VF5 hypothetical protein NP_213067.1 63986 R 224324 CDS NP_213068.1 15605692 1192520 complement(64729..65841) 1 NC_000918.1 hypothetical protein 65841 1192520 aq_104 Aquifex aeolicus VF5 hypothetical protein NP_213068.1 64729 R 224324 CDS NP_213070.1 15607135 1193998 complement(65828..66151) 1 NC_000918.1 ribosome-binding factor A 66151 rbfA 1193998 rbfA Aquifex aeolicus VF5 ribosome-binding factor A NP_213070.1 65828 R 224324 CDS NP_213072.1 15605695 1192523 complement(66900..67142) 1 NC_000918.1 host factor I 67142 hfq 1192523 hfq Aquifex aeolicus VF5 host factor I NP_213072.1 66900 R 224324 CDS NP_213073.1 15605696 1192524 67339..67677 1 NC_000918.1 nitrogen regulatory PII protein 67677 glnB 1192524 glnB Aquifex aeolicus VF5 nitrogen regulatory PII protein NP_213073.1 67339 D 224324 CDS NP_213074.1 15605697 1192525 67698..69107 1 NC_000918.1 glutamine synthetase 69107 glnA 1192525 glnA Aquifex aeolicus VF5 glutamine synthetase NP_213074.1 67698 D 224324 CDS NP_213075.1 15605698 1192526 69169..70440 1 NC_000918.1 ammonium transporter 70440 amtB 1192526 amtB Aquifex aeolicus VF5 ammonium transporter NP_213075.1 69169 D 224324 CDS NP_213076.1 15605699 1192527 70454..71500 1 NC_000918.1 hypothetical protein 71500 1192527 aq_113 Aquifex aeolicus VF5 hypothetical protein NP_213076.1 70454 D 224324 CDS NP_213077.1 15605700 1192528 complement(71803..72243) 1 NC_000918.1 hypothetical protein 72243 1192528 aq_114 Aquifex aeolicus VF5 hypothetical protein NP_213077.1 71803 R 224324 CDS NP_213078.1 15605701 1192529 complement(72560..74122) 1 NC_000918.1 hypothetical protein 74122 1192529 aq_116 Aquifex aeolicus VF5 hypothetical protein NP_213078.1 72560 R 224324 CDS NP_213079.1 15605702 1192530 complement(74123..75316) 1 NC_000918.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 75316 pgk 1192530 pgk Aquifex aeolicus VF5 phosphoglycerate kinase NP_213079.1 74123 R 224324 CDS NP_213080.1 15605703 1192531 complement(75328..75981) 1 NC_000918.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 75981 talC 1192531 talC Aquifex aeolicus VF5 translaldolase NP_213080.1 75328 R 224324 CDS NP_213081.1 15605704 1192532 complement(76010..77038) 1 NC_000918.1 hypothetical protein 77038 1192532 aq_121 Aquifex aeolicus VF5 hypothetical protein NP_213081.1 76010 R 224324 CDS NP_213082.1 15605705 1192665 complement(77035..78246) 1 NC_000918.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 78246 hisS 1192665 hisS Aquifex aeolicus VF5 histidyl-tRNA synthetase NP_213082.1 77035 R 224324 CDS NP_213083.1 15605706 1192666 78328..78666 1 NC_000918.1 30S ribosomal protein S16 78666 rpsP 1192666 rpsP Aquifex aeolicus VF5 30S ribosomal protein S16 NP_213083.1 78328 D 224324 CDS NP_213084.1 15605707 1192667 78663..78902 1 NC_000918.1 hypothetical protein 78902 1192667 aq_124a Aquifex aeolicus VF5 hypothetical protein NP_213084.1 78663 D 224324 CDS NP_213085.1 15605708 1192668 78902..79300 1 NC_000918.1 hypothetical protein 79300 1192668 aq_125 Aquifex aeolicus VF5 hypothetical protein NP_213085.1 78902 D 224324 CDS NP_213086.1 15605709 1192669 79305..79748 1 NC_000918.1 hypothetical protein 79748 1192669 aq_126 Aquifex aeolicus VF5 hypothetical protein NP_213086.1 79305 D 224324 CDS NP_213087.1 15605710 1192670 79748..80566 1 NC_000918.1 hypothetical protein 80566 1192670 aq_127 Aquifex aeolicus VF5 hypothetical protein NP_213087.1 79748 D 224324 CDS NP_213088.1 15605711 1192671 complement(80390..81808) 1 NC_000918.1 hypothetical protein 81808 1192671 aq_128 Aquifex aeolicus VF5 hypothetical protein NP_213088.1 80390 R 224324 CDS NP_213089.1 15605712 1192672 81823..82287 1 NC_000918.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 82287 ribH 1192672 ribH Aquifex aeolicus VF5 6,7-dimethyl-8-ribityllumazine synthase NP_213089.1 81823 D 224324 CDS NP_213090.1 15605713 1192673 82284..82730 1 NC_000918.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 82730 nusB 1192673 nusB Aquifex aeolicus VF5 transcription antitermination protein NusB NP_213090.1 82284 D 224324 CDS NP_213091.1 15605714 1192674 82932..83387 1 NC_000918.1 hypothetical protein 83387 1192674 aq_134 Aquifex aeolicus VF5 hypothetical protein NP_213091.1 82932 D 224324 CDS NP_213092.1 15605715 1192675 83384..84331 1 NC_000918.1 NADH dehydrogenase (ubiquinone) 84331 nueM 1192675 nueM Aquifex aeolicus VF5 NADH dehydrogenase (ubiquinone) NP_213092.1 83384 D 224324 CDS NP_213093.1 15605716 1192676 84354..85421 1 NC_000918.1 cytochrome C peroxidase 85421 cpx 1192676 cpx Aquifex aeolicus VF5 cytochrome C peroxidase NP_213093.1 84354 D 224324 CDS NP_213094.1 15605717 1192677 complement(85418..86488) 1 NC_000918.1 riboflavin specific deaminase 86488 ribD1 1192677 ribD1 Aquifex aeolicus VF5 riboflavin specific deaminase NP_213094.1 85418 R 224324 CDS NP_213095.1 15605718 1192678 complement(86485..87429) 1 NC_000918.1 riboflavin kinase 87429 ribF 1192678 ribF Aquifex aeolicus VF5 riboflavin kinase NP_213095.1 86485 R 224324 CDS NP_213096.1 15605719 1192679 complement(87436..87801) 1 NC_000918.1 protein kinase C inhibitor 87801 pkcI 1192679 pkcI Aquifex aeolicus VF5 protein kinase C inhibitor NP_213096.1 87436 R 224324 CDS NP_213097.1 15605720 1192680 88156..88596 1 NC_000918.1 hypothetical protein 88596 1192680 aq_142 Aquifex aeolicus VF5 hypothetical protein NP_213097.1 88156 D 224324 CDS NP_213098.1 15605721 1192681 88593..89546 1 NC_000918.1 ADP-heptose--LPS heptosyltransferase 89546 rfaC2 1192681 rfaC2 Aquifex aeolicus VF5 ADP-heptose--LPS heptosyltransferase NP_213098.1 88593 D 224324 CDS NP_213099.1 15605722 1192682 89543..90421 1 NC_000918.1 cobalamin synthesis related protein CobW 90421 cobW 1192682 cobW Aquifex aeolicus VF5 cobalamin synthesis related protein CobW NP_213099.1 89543 D 224324 CDS NP_213100.1 15605723 1192683 90418..91077 1 NC_000918.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 91077 deoC 1192683 deoC Aquifex aeolicus VF5 deoxyribose-phosphate aldolase NP_213100.1 90418 D 224324 CDS NP_213101.1 15605724 1192684 91085..91864 1 NC_000918.1 Catalyzes the first step in the citric acid cycle. Oxaloacetate and acetyl-CoA bind to citrate synthase, which then catalyzes the reaction which joins the two compounds together; citrate synthase 91864 gltA 1192684 gltA Aquifex aeolicus VF5 citrate synthase NP_213101.1 91085 D 224324 CDS NP_213102.1 15605725 1192685 91861..92301 1 NC_000918.1 thiol disulfide interchange protein 92301 tlpA 1192685 tlpA Aquifex aeolicus VF5 thiol disulfide interchange protein NP_213102.1 91861 D 224324 CDS NP_213103.1 15605726 1192686 92881..93771 1 NC_000918.1 heme O oxygenase 93771 ctaA 1192686 ctaA Aquifex aeolicus VF5 heme O oxygenase NP_213103.1 92881 D 224324 CDS NP_213104.1 15605727 1192687 93768..94646 1 NC_000918.1 cytochrome C oxidase assembly factor 94646 ctaB 1192687 ctaB Aquifex aeolicus VF5 cytochrome C oxidase assembly factor NP_213104.1 93768 D 224324 CDS NP_213105.1 15605728 1192688 94648..95808 1 NC_000918.1 hypothetical protein 95808 1192688 aq_155 Aquifex aeolicus VF5 hypothetical protein NP_213105.1 94648 D 224324 CDS NP_213106.1 15605729 1192689 96008..96406 1 NC_000918.1 hypothetical protein 96406 1192689 aq_156 Aquifex aeolicus VF5 hypothetical protein NP_213106.1 96008 D 224324 CDS NP_213107.1 15605730 1192690 96408..96896 1 NC_000918.1 hypothetical protein 96896 1192690 aq_157 Aquifex aeolicus VF5 hypothetical protein NP_213107.1 96408 D 224324 CDS NP_213108.1 15605731 1192691 96893..97297 1 NC_000918.1 AP4A hydrolase 97297 apfA 1192691 apfA Aquifex aeolicus VF5 AP4A hydrolase NP_213108.1 96893 D 224324 CDS NP_213110.1 15605733 1192693 98536..99018 1 NC_000918.1 folate biosynthesis 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 99018 folK 1192693 folK Aquifex aeolicus VF5 folate biosynthesis 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase NP_213110.1 98536 D 224324 CDS NP_213111.1 15605734 1192694 99015..100343 1 NC_000918.1 NtrC family transcriptional regulator 100343 ntrC4 1192694 ntrC4 Aquifex aeolicus VF5 NtrC family transcriptional regulator NP_213111.1 99015 D 224324 CDS NP_213112.1 15605735 1192695 complement(100330..101019) 1 NC_000918.1 hypothetical protein 101019 1192695 aq_165 Aquifex aeolicus VF5 hypothetical protein NP_213112.1 100330 R 224324 CDS NP_213113.1 15605736 1192696 101014..101811 1 NC_000918.1 pyrroline carboxylate reductase 101811 proC 1192696 proC Aquifex aeolicus VF5 pyrroline carboxylate reductase NP_213113.1 101014 D 224324 CDS NP_213114.1 15605737 1192697 101772..102392 1 NC_000918.1 hypothetical protein 102392 1192697 aq_167 Aquifex aeolicus VF5 hypothetical protein NP_213114.1 101772 D 224324 CDS NP_213117.1 15605740 1192700 complement(103299..104660) 1 NC_000918.1 DAPA aminotransferase 104660 bioA 1192700 bioA Aquifex aeolicus VF5 DAPA aminotransferase NP_213117.1 103299 R 224324 CDS NP_213118.1 15605741 1192701 104858..105598 1 NC_000918.1 hypothetical protein 105598 1192701 aq_171 Aquifex aeolicus VF5 hypothetical protein NP_213118.1 104858 D 224324 CDS NP_213119.1 15605742 1192702 complement(105912..106574) 1 NC_000918.1 endonuclease III 106574 mutY2 1192702 mutY2 Aquifex aeolicus VF5 endonuclease III NP_213119.1 105912 R 224324 CDS NP_213120.1 15605743 1192703 complement(106547..107290) 1 NC_000918.1 hypothetical protein 107290 1192703 aq_173 Aquifex aeolicus VF5 hypothetical protein NP_213120.1 106547 R 224324 CDS NP_213121.1 15605744 1192704 complement(107287..108795) 1 NC_000918.1 hypothetical protein 108795 1192704 aq_175 Aquifex aeolicus VF5 hypothetical protein NP_213121.1 107287 R 224324 CDS NP_213122.1 15605745 1194000 complement(108792..108998) 1 NC_000918.1 hypothetical protein 108998 1194000 aq_175a Aquifex aeolicus VF5 hypothetical protein NP_213122.1 108792 R 224324 CDS NP_213123.1 15605746 1192705 complement(109002..109145) 1 NC_000918.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 109145 rpmH 1192705 rpmH Aquifex aeolicus VF5 50S ribosomal protein L34 NP_213123.1 109002 R 224324 CDS NP_213124.1 15605747 1192706 complement(109189..109491) 1 NC_000918.1 ATP synthase F0 subunit c 109491 atpE 1192706 atpE Aquifex aeolicus VF5 ATP synthase F0 subunit c NP_213124.1 109189 R 224324 CDS NP_213125.1 15605748 1192707 complement(109507..109914) 1 NC_000918.1 hypothetical protein 109914 1192707 aq_178 Aquifex aeolicus VF5 hypothetical protein NP_213125.1 109507 R 224324 CDS NP_213126.1 15605749 1192708 complement(109916..110566) 1 NC_000918.1 ATP synthase F0 subunit a 110566 atpB 1192708 atpB Aquifex aeolicus VF5 ATP synthase F0 subunit a NP_213126.1 109916 R 224324 CDS NP_213127.1 15605750 1192709 110616..111377 1 NC_000918.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 111377 hisF 1192709 hisF Aquifex aeolicus VF5 imidazole glycerol phosphate synthase subunit HisF NP_213127.1 110616 D 224324 CDS NP_213128.1 15605751 1192710 complement(111355..112101) 1 NC_000918.1 hypothetical protein 112101 1192710 aq_182 Aquifex aeolicus VF5 hypothetical protein NP_213128.1 111355 R 224324 CDS NP_213129.1 15605752 1192711 complement(112111..113304) 1 NC_000918.1 hypothetical protein 113304 1192711 aq_183 Aquifex aeolicus VF5 hypothetical protein NP_213129.1 112111 R 224324 CDS NP_213130.1 15605753 1192712 complement(113301..113531) 1 NC_000918.1 RNA polymerase subunit omega 113531 rpoZ 1192712 rpoZ Aquifex aeolicus VF5 RNA polymerase subunit omega NP_213130.1 113301 R 224324 CDS NP_213132.1 15605755 1192714 complement(114179..114652) 1 NC_000918.1 glycerol-3-phosphate cytidyltransferase 114652 tagD1 1192714 tagD1 Aquifex aeolicus VF5 glycerol-3-phosphate cytidyltransferase NP_213132.1 114179 R 224324 CDS NP_213133.1 15605756 1192715 complement(114649..116079) 1 NC_000918.1 aldehyde dehydrogenase 116079 aldH1 1192715 aldH1 Aquifex aeolicus VF5 aldehyde dehydrogenase NP_213133.1 114649 R 224324 CDS NP_213134.1 15605757 1192716 complement(116090..117442) 1 NC_000918.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 117442 hslU 1192716 hslU Aquifex aeolicus VF5 ATP-dependent protease ATP-binding subunit HslU NP_213134.1 116090 R 224324 CDS NP_213135.1 15605758 1192717 complement(117420..117884) 1 NC_000918.1 hypothetical protein 117884 1192717 aq_194 Aquifex aeolicus VF5 hypothetical protein NP_213135.1 117420 R 224324 CDS NP_213136.1 15605759 1192718 117938..118960 1 NC_000918.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 118960 trpD 1192718 trpD Aquifex aeolicus VF5 anthranilate phosphoribosyltransferase NP_213136.1 117938 D 224324 CDS NP_213137.1 15605760 1192719 118960..120162 1 NC_000918.1 hypothetical protein 120162 1192719 aq_197 Aquifex aeolicus VF5 hypothetical protein NP_213137.1 118960 D 224324 CDS NP_213138.1 15605761 1192720 120228..121451 1 NC_000918.1 hypothetical protein 121451 1192720 aq_199 Aquifex aeolicus VF5 hypothetical protein NP_213138.1 120228 D 224324 CDS NP_213139.1 15605762 1192721 121448..122074 1 NC_000918.1 hypothetical protein 122074 1192721 aq_200 Aquifex aeolicus VF5 hypothetical protein NP_213139.1 121448 D 224324 CDS NP_213140.1 15605763 1192722 122071..122679 1 NC_000918.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 122679 1192722 aq_202 Aquifex aeolicus VF5 deoxyribonucleotide triphosphate pyrophosphatase NP_213140.1 122071 D 224324 CDS NP_213141.1 15605764 1192723 122663..123844 1 NC_000918.1 ATP synthase F1 subunit gamma 123844 atpG2 1192723 atpG2 Aquifex aeolicus VF5 ATP synthase F1 subunit gamma NP_213141.1 122663 D 224324 CDS NP_213142.1 15605765 1192724 complement(123819..124700) 1 NC_000918.1 hypothetical protein 124700 1192724 aq_204 Aquifex aeolicus VF5 hypothetical protein NP_213142.1 123819 R 224324 CDS NP_213143.1 15605766 1192725 124821..127829 1 NC_000918.1 nitrite reductase (NAD(P)H) large subunit 127829 nirB 1192725 nirB Aquifex aeolicus VF5 nitrite reductase (NAD(P)H) large subunit NP_213143.1 124821 D 224324 CDS NP_213144.1 15605767 1192818 127845..128579 1 NC_000918.1 uroporphyrin-III c-methyltransferase 128579 cobA 1192818 cobA Aquifex aeolicus VF5 uroporphyrin-III c-methyltransferase NP_213144.1 127845 D 224324 CDS NP_213145.1 15605768 1192819 128584..129513 1 NC_000918.1 phosphoribosylanthranilate transferase 129513 trpD2 1192819 trpD2 Aquifex aeolicus VF5 phosphoribosylanthranilate transferase NP_213145.1 128584 D 224324 CDS NP_213146.1 15605769 1192820 129647..130066 1 NC_000918.1 flavohemoprotein 130066 fhp 1192820 fhp Aquifex aeolicus VF5 flavohemoprotein NP_213146.1 129647 D 224324 CDS NP_213147.1 15605770 1192821 130079..130528 1 NC_000918.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 130528 cynS 1192821 cynS Aquifex aeolicus VF5 cyanate hydratase NP_213147.1 130079 D 224324 CDS NP_213148.1 15605771 1192822 130544..131161 1 NC_000918.1 PII-like protein GlnBi 131161 glnBi 1192822 glnBi Aquifex aeolicus VF5 PII-like protein GlnBi NP_213148.1 130544 D 224324 CDS NP_213149.1 15605772 1192823 131158..132585 1 NC_000918.1 nitrate transporter 132585 nasA 1192823 nasA Aquifex aeolicus VF5 nitrate transporter NP_213149.1 131158 D 224324 CDS NP_213150.1 15605773 1192824 132582..134582 1 NC_000918.1 nitrate reductase narB 134582 narB 1192824 narB Aquifex aeolicus VF5 nitrate reductase narB NP_213150.1 132582 D 224324 CDS NP_213151.1 15605774 1192825 complement(134585..136105) 1 NC_000918.1 NifA family transcriptional regulator 136105 nifA 1192825 nifA Aquifex aeolicus VF5 NifA family transcriptional regulator NP_213151.1 134585 R 224324 CDS NP_213152.1 15605775 1192826 complement(136122..136574) 1 NC_000918.1 deoxyuridine 5'triphosphate nucleotidohydrolase 136574 dut 1192826 dut Aquifex aeolicus VF5 deoxyuridine 5'triphosphate nucleotidohydrolase NP_213152.1 136122 R 224324 CDS NP_213153.1 15605776 1192827 complement(136567..138894) 1 NC_000918.1 polynucleotide phosphorylase/polyadenylase 138894 phpA 1192827 phpA Aquifex aeolicus VF5 polynucleotide phosphorylase/polyadenylase NP_213153.1 136567 R 224324 CDS NP_213154.1 15605777 1192828 complement(138897..139169) 1 NC_000918.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 139169 rpsO 1192828 rpsO Aquifex aeolicus VF5 30S ribosomal protein S15 NP_213154.1 138897 R 224324 CDS NP_213155.1 15605778 1192829 complement(139228..141390) 1 NC_000918.1 aldehyde dehydrogenase 141390 aldH2 1192829 aldH2 Aquifex aeolicus VF5 aldehyde dehydrogenase NP_213155.1 139228 R 224324 CDS NP_213156.1 15605779 1192830 141804..143150 1 NC_000918.1 NtrC family transcriptional regulator 143150 ntrC3 1192830 ntrC3 Aquifex aeolicus VF5 NtrC family transcriptional regulator NP_213156.1 141804 D 224324 CDS NP_213157.1 15605780 1192831 complement(143094..144113) 1 NC_000918.1 histidine kinase sensor protein 144113 hksP4 1192831 hksP4 Aquifex aeolicus VF5 histidine kinase sensor protein NP_213157.1 143094 R 224324 CDS NP_213158.1 15605781 1192832 144275..145585 1 NC_000918.1 flavocytochrome C sulfide dehydrogenase 145585 dhsU 1192832 dhsU Aquifex aeolicus VF5 flavocytochrome C sulfide dehydrogenase NP_213158.1 144275 D 224324 CDS NP_213159.1 15605782 1192833 145595..146311 1 NC_000918.1 Rieske-I iron sulfur protein 146311 soxF 1192833 soxF Aquifex aeolicus VF5 Rieske-I iron sulfur protein NP_213159.1 145595 D 224324 CDS NP_213160.1 15605783 1192834 146292..147545 1 NC_000918.1 sulfide dehydrogenase, flavoprotein subunit 147545 fccB' 1192834 fccB' Aquifex aeolicus VF5 sulfide dehydrogenase, flavoprotein subunit NP_213160.1 146292 D 224324 CDS NP_213161.1 15605784 1192835 complement(147546..149078) 1 NC_000918.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 149078 guaA 1192835 guaA Aquifex aeolicus VF5 GMP synthase NP_213161.1 147546 R 224324 CDS NP_213162.1 15605785 1192836 149124..149639 1 NC_000918.1 superoxide dismutase (Cu/Zn) 149639 sodC2 1192836 sodC2 Aquifex aeolicus VF5 superoxide dismutase (Cu/Zn) NP_213162.1 149124 D 224324 CDS NP_213163.1 15605786 1192837 149720..150274 1 NC_000918.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 150274 folE 1192837 folE Aquifex aeolicus VF5 GTP cyclohydrolase I NP_213163.1 149720 D 224324 CDS NP_213164.1 15605787 1192838 complement(150271..151173) 1 NC_000918.1 hypothetical protein 151173 1192838 aq_240 Aquifex aeolicus VF5 hypothetical protein NP_213164.1 150271 R 224324 CDS NP_213165.1 15605788 1192839 151206..153593 1 NC_000918.1 Lon protease 153593 lon 1192839 lon Aquifex aeolicus VF5 Lon protease NP_213165.1 151206 D 224324 CDS NP_213166.1 15605789 1192840 complement(153580..155067) 1 NC_000918.1 hypothetical protein 155067 1192840 aq_243 Aquifex aeolicus VF5 hypothetical protein NP_213166.1 153580 R 224324 CDS NP_213167.1 15605790 1192841 complement(155054..156148) 1 NC_000918.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 156148 leuB 1192841 leuB Aquifex aeolicus VF5 3-isopropylmalate dehydrogenase NP_213167.1 155054 R 224324 CDS NP_213168.1 15605791 1192842 156794..157891 1 NC_000918.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 157891 purK 1192842 purK Aquifex aeolicus VF5 phosphoribosylaminoimidazole carboxylase ATPase subunit NP_213168.1 156794 D 224324 CDS NP_213169.1 15605792 1192843 complement(157857..158696) 1 NC_000918.1 hypothetical protein 158696 1192843 aq_246 Aquifex aeolicus VF5 hypothetical protein NP_213169.1 157857 R 224324 CDS NP_213170.1 15605793 1192844 complement(158696..160132) 1 NC_000918.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 160132 gatA 1192844 gatA Aquifex aeolicus VF5 aspartyl/glutamyl-tRNA amidotransferase subunit A NP_213170.1 158696 R 224324 CDS NP_213171.1 15605794 1192845 complement(160145..160582) 1 NC_000918.1 hypothetical protein 160582 1192845 aq_250 Aquifex aeolicus VF5 hypothetical protein NP_213171.1 160145 R 224324 CDS NP_213172.1 15605795 1192846 complement(160629..161309) 1 NC_000918.1 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites; N-glycosylase/DNA lyase 161309 1192846 aq_251 Aquifex aeolicus VF5 N-glycosylase/DNA lyase NP_213172.1 160629 R 224324 CDS NP_213173.1 15605796 1192847 complement(161325..161744) 1 NC_000918.1 hypothetical protein 161744 1192847 aq_252 Aquifex aeolicus VF5 hypothetical protein NP_213173.1 161325 R 224324 CDS NP_213174.1 15605797 1192848 complement(161732..162217) 1 NC_000918.1 lipopolysaccharide core biosynthesis protein 162217 kdtB 1192848 kdtB Aquifex aeolicus VF5 lipopolysaccharide core biosynthesis protein NP_213174.1 161732 R 224324 CDS NP_213175.1 15605798 1192849 162752..163159 1 NC_000918.1 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 163159 1192849 aq_254 Aquifex aeolicus VF5 S-adenosylmethionine decarboxylase NP_213175.1 162752 D 224324 CDS NP_213176.1 15605799 1192850 163193..163678 1 NC_000918.1 hypothetical protein 163678 1192850 aq_255 Aquifex aeolicus VF5 hypothetical protein NP_213176.1 163193 D 224324 CDS NP_213177.1 15605800 1192851 complement(164100..165377) 1 NC_000918.1 RNA methyltransferase 165377 ygcA 1192851 ygcA Aquifex aeolicus VF5 RNA methyltransferase NP_213177.1 164100 R 224324 CDS NP_213178.1 15605801 1192852 complement(165358..166371) 1 NC_000918.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 166371 nusA 1192852 nusA Aquifex aeolicus VF5 transcription elongation factor NusA NP_213178.1 165358 R 224324 CDS NP_213179.1 15605802 1192853 complement(166365..166841) 1 NC_000918.1 hypothetical protein 166841 1192853 aq_260 Aquifex aeolicus VF5 hypothetical protein NP_213179.1 166365 R 224324 CDS YP_008920727.1 566344047 17925346 complement(167377..167571) 1 NC_000918.1 hypothetical protein 167571 17925346 aq_260a Aquifex aeolicus VF5 hypothetical protein YP_008920727.1 167377 R 224324 CDS NP_213180.1 15605803 1192854 complement(167586..168155) 1 NC_000918.1 hypothetical protein 168155 1192854 aq_262 Aquifex aeolicus VF5 hypothetical protein NP_213180.1 167586 R 224324 CDS NP_213181.1 15605804 1192855 168918..169889 1 NC_000918.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 169889 hemC 1192855 hemC Aquifex aeolicus VF5 porphobilinogen deaminase NP_213181.1 168918 D 224324 CDS NP_213182.1 15605805 1192856 169886..170539 1 NC_000918.1 hypothetical protein 170539 1192856 aq_264 Aquifex aeolicus VF5 hypothetical protein NP_213182.1 169886 D 224324 CDS NP_213183.1 15605806 1192857 complement(170475..171491) 1 NC_000918.1 hypothetical protein 171491 1192857 aq_265 Aquifex aeolicus VF5 hypothetical protein NP_213183.1 170475 R 224324 CDS NP_213184.1 15605807 1192858 171596..172732 1 NC_000918.1 hypothetical protein 172732 1192858 aq_267 Aquifex aeolicus VF5 hypothetical protein NP_213184.1 171596 D 224324 CDS NP_213185.1 15605808 1192859 172848..173318 1 NC_000918.1 hypothetical protein 173318 1192859 aq_268 Aquifex aeolicus VF5 hypothetical protein NP_213185.1 172848 D 224324 CDS NP_213186.1 15605809 1192860 complement(173338..173826) 1 NC_000918.1 hypothetical protein 173826 1192860 aq_269 Aquifex aeolicus VF5 hypothetical protein NP_213186.1 173338 R 224324 CDS NP_213187.1 15605810 1192861 173860..174678 1 NC_000918.1 prolipoprotein diacylglyceryl transferase 174678 lgt 1192861 lgt Aquifex aeolicus VF5 prolipoprotein diacylglyceryl transferase NP_213187.1 173860 D 224324 CDS NP_213188.1 15605811 1192862 174675..175886 1 NC_000918.1 hypothetical protein 175886 1192862 aq_271 Aquifex aeolicus VF5 hypothetical protein NP_213188.1 174675 D 224324 CDS NP_213189.1 15605812 1192863 complement(175879..176328) 1 NC_000918.1 hypothetical protein 176328 1192863 aq_272 Aquifex aeolicus VF5 hypothetical protein NP_213189.1 175879 R 224324 CDS NP_213190.1 15605813 1192864 176409..177572 1 NC_000918.1 catalyzes the formation of LL-diaminopimelate from tetrahydrodipicolinate; involved in lysine and peptidoglycan synthesis; LL-diaminopimelate aminotransferase 177572 aspC4 1192864 aspC4 Aquifex aeolicus VF5 LL-diaminopimelate aminotransferase NP_213190.1 176409 D 224324 CDS NP_213191.1 15605814 1192865 177613..178299 1 NC_000918.1 hypothetical protein 178299 1192865 aq_274 Aquifex aeolicus VF5 hypothetical protein NP_213191.1 177613 D 224324 CDS NP_213192.1 15605815 1192866 complement(178587..179963) 1 NC_000918.1 hypothetical protein 179963 1192866 aq_276 Aquifex aeolicus VF5 hypothetical protein NP_213192.1 178587 R 224324 CDS NP_213195.1 15605818 1192869 complement(183235..183774) 1 NC_000918.1 TetR/AcrR family transcriptional regulator 183774 acrR3 1192869 acrR3 Aquifex aeolicus VF5 TetR/AcrR family transcriptional regulator NP_213195.1 183235 R 224324 CDS NP_213196.1 15605819 1192870 183890..184531 1 NC_000918.1 endonuclease III 184531 mutY1 1192870 mutY1 Aquifex aeolicus VF5 endonuclease III NP_213196.1 183890 D 224324 CDS NP_213197.1 15605820 1192871 complement(184528..185025) 1 NC_000918.1 hypothetical protein 185025 1192871 aq_283 Aquifex aeolicus VF5 hypothetical protein NP_213197.1 184528 R 224324 CDS NP_213198.1 15605821 1192872 complement(185022..186344) 1 NC_000918.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 186344 1192872 aq_284 Aquifex aeolicus VF5 (dimethylallyl)adenosine tRNA methylthiotransferase NP_213198.1 185022 R 224324 CDS NP_213199.1 15605822 1192873 complement(186373..186900) 1 NC_000918.1 hypothetical protein 186900 1192873 aq_286 Aquifex aeolicus VF5 hypothetical protein NP_213199.1 186373 R 224324 CDS NP_213200.1 15605823 1192874 complement(186900..187373) 1 NC_000918.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 187373 smpB 1192874 smpB Aquifex aeolicus VF5 SsrA-binding protein NP_213200.1 186900 R 224324 CDS NP_213201.1 15605824 1192875 complement(187381..188349) 1 NC_000918.1 hypothetical protein 188349 1192875 aq_288 Aquifex aeolicus VF5 hypothetical protein NP_213201.1 187381 R 224324 CDS NP_213202.1 15605825 1192876 188378..189856 1 NC_000918.1 hypothetical protein 189856 1192876 aq_291 Aquifex aeolicus VF5 hypothetical protein NP_213202.1 188378 D 224324 CDS NP_213203.1 15605826 1192877 189867..190262 1 NC_000918.1 hypothetical protein 190262 1192877 aq_293 Aquifex aeolicus VF5 hypothetical protein NP_213203.1 189867 D 224324 CDS NP_213204.1 15605827 1192878 190268..191383 1 NC_000918.1 hypothetical protein 191383 1192878 aq_294 Aquifex aeolicus VF5 hypothetical protein NP_213204.1 190268 D 224324 CDS NP_213205.1 15605828 1192879 191380..192630 1 NC_000918.1 hypothetical protein 192630 1192879 aq_296 Aquifex aeolicus VF5 hypothetical protein NP_213205.1 191380 D 224324 CDS NP_213206.1 15605829 1192880 192623..193297 1 NC_000918.1 ABC transporter 193297 abcT8 1192880 abcT8 Aquifex aeolicus VF5 ABC transporter NP_213206.1 192623 D 224324 CDS NP_213207.1 15605830 1192881 complement(193284..194561) 1 NC_000918.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 194561 serS 1192881 serS Aquifex aeolicus VF5 seryl-tRNA synthetase NP_213207.1 193284 R 224324 CDS NP_213208.1 15605831 1192882 194591..196369 1 NC_000918.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 196369 glmS 1192882 glmS Aquifex aeolicus VF5 glucosamine--fructose-6-phosphate aminotransferase NP_213208.1 194591 D 224324 CDS NP_213209.1 15605832 1192883 complement(196370..196714) 1 NC_000918.1 hypothetical protein 196714 1192883 aq_302 Aquifex aeolicus VF5 hypothetical protein NP_213209.1 196370 R 224324 CDS NP_213210.1 15605833 1192884 complement(196711..197817) 1 NC_000918.1 hypothetical protein 197817 1192884 aq_303 Aquifex aeolicus VF5 hypothetical protein NP_213210.1 196711 R 224324 CDS NP_213211.1 15605834 1192885 complement(197804..200674) 1 NC_000918.1 isoleucyl-tRNA synthetase 200674 ileS 1192885 ileS Aquifex aeolicus VF5 isoleucyl-tRNA synthetase NP_213211.1 197804 R 224324 CDS NP_213212.1 15605835 1192886 200713..203292 1 NC_000918.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 203292 mutS1 1192886 mutS1 Aquifex aeolicus VF5 DNA mismatch repair protein MutS NP_213212.1 200713 D 224324 CDS NP_213213.1 15605836 1192887 complement(204008..204754) 1 NC_000918.1 hypothetical protein 204754 1192887 aq_311 Aquifex aeolicus VF5 hypothetical protein NP_213213.1 204008 R 224324 CDS NP_213214.1 15605837 1192888 complement(204741..205580) 1 NC_000918.1 hypothetical protein 205580 1192888 aq_313 Aquifex aeolicus VF5 hypothetical protein NP_213214.1 204741 R 224324 CDS NP_213215.1 15605838 1192889 complement(205589..206026) 1 NC_000918.1 hypothetical protein 206026 1192889 aq_314 Aquifex aeolicus VF5 hypothetical protein NP_213215.1 205589 R 224324 CDS NP_213216.1 15605839 1192890 complement(206135..207067) 1 NC_000918.1 histidine kinase sensor protein 207067 hksP2 1192890 hksP2 Aquifex aeolicus VF5 histidine kinase sensor protein NP_213216.1 206135 R 224324 CDS NP_213217.1 15605840 1192891 207352..208038 1 NC_000918.1 PhoB family transcriptional regulator 208038 phoB 1192891 phoB Aquifex aeolicus VF5 PhoB family transcriptional regulator NP_213217.1 207352 D 224324 CDS NP_213218.1 15605841 1192892 208049..208645 1 NC_000918.1 hypothetical protein 208645 1192892 aq_321 Aquifex aeolicus VF5 hypothetical protein NP_213218.1 208049 D 224324 CDS NP_213219.1 15605842 1192893 complement(208642..209841) 1 NC_000918.1 chromosome replication initiator protein DnaA 209841 dnaA 1192893 dnaA Aquifex aeolicus VF5 chromosome replication initiator protein DnaA NP_213219.1 208642 R 224324 CDS NP_213220.1 15605843 1192894 complement(209932..210942) 1 NC_000918.1 hypothetical protein 210942 1192894 aq_323 Aquifex aeolicus VF5 hypothetical protein NP_213220.1 209932 R 224324 CDS NP_213221.1 15605844 1192895 211034..211816 1 NC_000918.1 hypothetical protein 211816 1192895 aq_324 Aquifex aeolicus VF5 hypothetical protein NP_213221.1 211034 D 224324 CDS NP_213222.1 15605845 1192896 complement(211813..212577) 1 NC_000918.1 glutamate racemase 212577 murI 1192896 murI Aquifex aeolicus VF5 glutamate racemase NP_213222.1 211813 R 224324 CDS NP_213223.1 15605846 1192897 212605..213666 1 NC_000918.1 3-deoxy-D-manno-2-octulosonate transferase 213666 kdtA 1192897 kdtA Aquifex aeolicus VF5 3-deoxy-D-manno-2-octulosonate transferase NP_213223.1 212605 D 224324 CDS NP_213224.1 15605847 1192898 complement(213641..214411) 1 NC_000918.1 hypothetical protein 214411 1192898 aq_327 Aquifex aeolicus VF5 hypothetical protein NP_213224.1 213641 R 224324 CDS NP_213225.1 15605848 1192899 214370..214885 1 NC_000918.1 hypothetical protein 214885 1192899 aq_328 Aquifex aeolicus VF5 hypothetical protein NP_213225.1 214370 D 224324 CDS NP_213226.1 15605849 1192900 214915..215796 1 NC_000918.1 hypothetical protein 215796 1192900 aq_331 Aquifex aeolicus VF5 hypothetical protein NP_213226.1 214915 D 224324 CDS NP_213227.1 15605850 1192901 215954..216970 1 NC_000918.1 uroporphyrinogen decarboxylase 216970 dcuP 1192901 dcuP Aquifex aeolicus VF5 uroporphyrinogen decarboxylase NP_213227.1 215954 D 224324 CDS NP_213229.1 15605852 1192903 complement(217910..218716) 1 NC_000918.1 CysQ protein 218716 cysQ 1192903 cysQ Aquifex aeolicus VF5 CysQ protein NP_213229.1 217910 R 224324 CDS NP_213230.1 15605853 1192904 complement(218720..219373) 1 NC_000918.1 hypothetical protein 219373 1192904 aq_338 Aquifex aeolicus VF5 hypothetical protein NP_213230.1 218720 R 224324 CDS NP_213231.1 15605854 1192905 219402..221159 1 NC_000918.1 hypothetical protein 221159 1192905 aq_340 Aquifex aeolicus VF5 hypothetical protein NP_213231.1 219402 D 224324 CDS NP_213232.1 15605855 1192906 222065..222556 1 NC_000918.1 hypothetical protein 222556 1192906 aq_341 Aquifex aeolicus VF5 hypothetical protein NP_213232.1 222065 D 224324 CDS NP_213233.1 15605856 1192907 222567..223340 1 NC_000918.1 hypothetical protein 223340 1192907 aq_342 Aquifex aeolicus VF5 hypothetical protein NP_213233.1 222567 D 224324 CDS NP_213234.1 15605857 1192908 complement(223332..224231) 1 NC_000918.1 anion transporting ATPase 224231 arsA2 1192908 arsA2 Aquifex aeolicus VF5 anion transporting ATPase NP_213234.1 223332 R 224324 CDS NP_213235.1 15605858 1192909 complement(224228..225160) 1 NC_000918.1 ADP-L-glycero-D-manno-heptose-6-epimerase 225160 rfaD 1192909 rfaD Aquifex aeolicus VF5 ADP-L-glycero-D-manno-heptose-6-epimerase NP_213235.1 224228 R 224324 CDS NP_213236.1 15605859 1193002 225588..227465 1 NC_000918.1 hypothetical protein 227465 1193002 aq_345 Aquifex aeolicus VF5 hypothetical protein NP_213236.1 225588 D 224324 CDS NP_213237.1 15605860 1193003 complement(227462..228040) 1 NC_000918.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 228040 pth 1193003 pth Aquifex aeolicus VF5 peptidyl-tRNA hydrolase NP_213237.1 227462 R 224324 CDS NP_213239.1 15605862 1193005 228716..229936 1 NC_000918.1 GTP cyclohydrolase II 229936 ribA 1193005 ribA Aquifex aeolicus VF5 GTP cyclohydrolase II NP_213239.1 228716 D 224324 CDS NP_213240.1 15605863 1193006 complement(229933..231837) 1 NC_000918.1 leucyl-tRNA synthetase 231837 leuS 1193006 leuS Aquifex aeolicus VF5 leucyl-tRNA synthetase NP_213240.1 229933 R 224324 CDS NP_213241.1 15605864 1193007 complement(231841..232578) 1 NC_000918.1 hypothetical protein 232578 1193007 aq_355 Aquifex aeolicus VF5 hypothetical protein NP_213241.1 231841 R 224324 CDS NP_213242.1 15605865 1193008 complement(232592..234178) 1 NC_000918.1 catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA; alpha-isopropylmalate/homocitrate synthase family transferase 234178 leuA1 1193008 leuA1 Aquifex aeolicus VF5 alpha-isopropylmalate/homocitrate synthase family transferase NP_213242.1 232592 R 224324 CDS NP_213243.1 15605866 1193009 234260..234526 1 NC_000918.1 anti sigma factor FlgM 234526 flgM 1193009 flgM Aquifex aeolicus VF5 anti sigma factor FlgM NP_213243.1 234260 D 224324 CDS NP_213244.1 15605867 1193010 234590..236518 1 NC_000918.1 ATP-dependent helicase DinG 236518 dinG 1193010 dinG Aquifex aeolicus VF5 ATP-dependent helicase DinG NP_213244.1 234590 D 224324 CDS NP_213245.1 15605868 1193011 236530..237600 1 NC_000918.1 hypothetical protein 237600 1193011 aq_359 Aquifex aeolicus VF5 hypothetical protein NP_213245.1 236530 D 224324 CDS NP_213246.1 15605869 1193012 complement(237559..238302) 1 NC_000918.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 238302 tpiA 1193012 tpiA Aquifex aeolicus VF5 triosephosphate isomerase NP_213246.1 237559 R 224324 CDS NP_213247.1 15605870 1193013 complement(238638..239435) 1 NC_000918.1 hypothetical protein 239435 1193013 aq_362 Aquifex aeolicus VF5 hypothetical protein NP_213247.1 238638 R 224324 CDS NP_213248.1 15605871 1193014 complement(239435..239866) 1 NC_000918.1 hypothetical protein 239866 1193014 aq_363 Aquifex aeolicus VF5 hypothetical protein NP_213248.1 239435 R 224324 CDS NP_213249.1 15605872 1193015 complement(239863..240240) 1 NC_000918.1 hypothetical protein 240240 1193015 aq_364 Aquifex aeolicus VF5 hypothetical protein NP_213249.1 239863 R 224324 CDS NP_213250.1 15605873 1193016 complement(240237..241949) 1 NC_000918.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 241949 proS 1193016 proS Aquifex aeolicus VF5 prolyl-tRNA synthetase NP_213250.1 240237 R 224324 CDS NP_213251.1 15605874 1193017 241994..244546 1 NC_000918.1 hypothetical protein 244546 1193017 aq_367 Aquifex aeolicus VF5 hypothetical protein NP_213251.1 241994 D 224324 CDS NP_213252.1 15605875 1193018 complement(245338..246288) 1 NC_000918.1 hypothetical protein 246288 1193018 aq_369 Aquifex aeolicus VF5 hypothetical protein NP_213252.1 245338 R 224324 CDS NP_213253.1 15605876 1193019 complement(246281..246814) 1 NC_000918.1 hypothetical protein 246814 1193019 aq_370 Aquifex aeolicus VF5 hypothetical protein NP_213253.1 246281 R 224324 CDS NP_213254.1 15605877 1193020 complement(246792..248981) 1 NC_000918.1 hypothetical protein 248981 1193020 aq_371 Aquifex aeolicus VF5 hypothetical protein NP_213254.1 246792 R 224324 CDS NP_213255.1 15605878 1193021 complement(248932..250527) 1 NC_000918.1 hypothetical protein 250527 1193021 aq_372 Aquifex aeolicus VF5 hypothetical protein NP_213255.1 248932 R 224324 CDS NP_213256.1 15605879 1193022 complement(250518..251177) 1 NC_000918.1 hypothetical protein 251177 1193022 aq_373 Aquifex aeolicus VF5 hypothetical protein NP_213256.1 250518 R 224324 CDS NP_213257.1 15605880 1193023 complement(251158..252231) 1 NC_000918.1 hypothetical protein 252231 1193023 aq_374 Aquifex aeolicus VF5 hypothetical protein NP_213257.1 251158 R 224324 CDS NP_213258.1 15605881 1193024 complement(252309..253250) 1 NC_000918.1 hypothetical protein 253250 1193024 aq_376 Aquifex aeolicus VF5 hypothetical protein NP_213258.1 252309 R 224324 CDS NP_213259.1 15605882 1193025 complement(253252..253587) 1 NC_000918.1 hypothetical protein 253587 1193025 aq_377 Aquifex aeolicus VF5 hypothetical protein NP_213259.1 253252 R 224324 CDS NP_213260.1 15605883 1193026 complement(253592..254953) 1 NC_000918.1 hypothetical protein 254953 1193026 aq_378 Aquifex aeolicus VF5 hypothetical protein NP_213260.1 253592 R 224324 CDS NP_213261.1 15605884 1193027 complement(254950..256071) 1 NC_000918.1 hypothetical protein 256071 1193027 aq_380 Aquifex aeolicus VF5 hypothetical protein NP_213261.1 254950 R 224324 CDS NP_213262.1 15605885 1193028 complement(256087..256986) 1 NC_000918.1 hypothetical protein 256986 1193028 aq_381 Aquifex aeolicus VF5 hypothetical protein NP_213262.1 256087 R 224324 CDS NP_213263.1 15605886 1193029 complement(257019..257906) 1 NC_000918.1 hypothetical protein 257906 1193029 aq_382 Aquifex aeolicus VF5 hypothetical protein NP_213263.1 257019 R 224324 CDS NP_213264.1 15605887 1193030 complement(257872..258615) 1 NC_000918.1 hypothetical protein 258615 1193030 aq_383 Aquifex aeolicus VF5 hypothetical protein NP_213264.1 257872 R 224324 CDS NP_213265.1 15605888 1193031 complement(258857..259258) 1 NC_000918.1 hypothetical protein 259258 1193031 aq_384 Aquifex aeolicus VF5 hypothetical protein NP_213265.1 258857 R 224324 CDS NP_213266.1 15605889 1193032 complement(259248..260135) 1 NC_000918.1 hypothetical protein 260135 1193032 aq_385 Aquifex aeolicus VF5 hypothetical protein NP_213266.1 259248 R 224324 CDS NP_213267.1 15605890 1193033 complement(260132..261109) 1 NC_000918.1 hypothetical protein 261109 1193033 aq_386 Aquifex aeolicus VF5 hypothetical protein NP_213267.1 260132 R 224324 CDS NP_213268.1 15605891 1193034 complement(261090..262955) 1 NC_000918.1 hypothetical protein 262955 1193034 aq_387 Aquifex aeolicus VF5 hypothetical protein NP_213268.1 261090 R 224324 CDS NP_213269.1 15605892 1193035 263585..264490 1 NC_000918.1 hypothetical protein 264490 1193035 aq_388 Aquifex aeolicus VF5 hypothetical protein NP_213269.1 263585 D 224324 CDS YP_008920728.1 566344048 17925347 264847..265086 1 NC_000918.1 response regulator SirA 265086 17925347 aq_388a Aquifex aeolicus VF5 response regulator SirA YP_008920728.1 264847 D 224324 CDS NP_213270.1 15605893 1193036 265099..265647 1 NC_000918.1 hypothetical protein 265647 1193036 aq_389 Aquifex aeolicus VF5 hypothetical protein NP_213270.1 265099 D 224324 CDS NP_213271.1 15605894 1193037 265667..266092 1 NC_000918.1 hypothetical protein 266092 1193037 aq_390 Aquifex aeolicus VF5 hypothetical protein NP_213271.1 265667 D 224324 CDS NP_213272.1 15605895 1193038 266219..266971 1 NC_000918.1 hypothetical protein 266971 1193038 aq_391 Aquifex aeolicus VF5 hypothetical protein NP_213272.1 266219 D 224324 CDS NP_213275.1 15605898 1193041 268431..269489 1 NC_000918.1 heterodisulfide reductase subunit A 269489 hdrA 1193041 hdrA Aquifex aeolicus VF5 heterodisulfide reductase subunit A NP_213275.1 268431 D 224324 CDS NP_213276.1 15605899 1193042 269486..270304 1 NC_000918.1 hypothetical protein 270304 1193042 aq_397 Aquifex aeolicus VF5 hypothetical protein NP_213276.1 269486 D 224324 CDS NP_213277.1 15605900 1193043 270319..271080 1 NC_000918.1 heterodisulfide reductase subunit C 271080 hdrC 1193043 hdrC Aquifex aeolicus VF5 heterodisulfide reductase subunit C NP_213277.1 270319 D 224324 CDS NP_213278.1 15605901 1193044 271093..272088 1 NC_000918.1 heterodisulfide reductase subunit B 272088 hdrB 1193044 hdrB Aquifex aeolicus VF5 heterodisulfide reductase subunit B NP_213278.1 271093 D 224324 CDS NP_213279.1 15605902 1193045 272163..272570 1 NC_000918.1 hypothetical protein 272570 1193045 aq_401 Aquifex aeolicus VF5 hypothetical protein NP_213279.1 272163 D 224324 CDS NP_213280.1 15605903 1193046 272598..273044 1 NC_000918.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 273044 1193046 aq_402 Aquifex aeolicus VF5 glycine cleavage system protein H NP_213280.1 272598 D 224324 CDS NP_213281.1 15605904 1193047 273087..274112 1 NC_000918.1 hypothetical protein 274112 1193047 aq_403 Aquifex aeolicus VF5 hypothetical protein NP_213281.1 273087 D 224324 CDS NP_213282.1 15605905 1193048 274129..275271 1 NC_000918.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 275271 1193048 aq_404 Aquifex aeolicus VF5 1-deoxy-D-xylulose 5-phosphate reductoisomerase NP_213282.1 274129 D 224324 CDS NP_213283.1 15605906 1193049 complement(275231..276100) 1 NC_000918.1 hypothetical protein 276100 1193049 aq_406 Aquifex aeolicus VF5 hypothetical protein NP_213283.1 275231 R 224324 CDS NP_213284.1 15605907 1193050 complement(276097..276708) 1 NC_000918.1 hypothetical protein 276708 1193050 aq_407 Aquifex aeolicus VF5 hypothetical protein NP_213284.1 276097 R 224324 CDS NP_213285.1 15605908 1193051 complement(276724..277248) 1 NC_000918.1 hypothetical protein 277248 1193051 aq_408 Aquifex aeolicus VF5 hypothetical protein NP_213285.1 276724 R 224324 CDS NP_213286.1 15605909 1193052 complement(277239..278114) 1 NC_000918.1 aspartate carbamoyltransferase 278114 pyrB 1193052 pyrB Aquifex aeolicus VF5 aspartate carbamoyltransferase NP_213286.1 277239 R 224324 CDS NP_213287.1 15605910 1193053 complement(278111..279226) 1 NC_000918.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 279226 carA 1193053 carA Aquifex aeolicus VF5 carbamoyl phosphate synthase small subunit NP_213287.1 278111 R 224324 CDS NP_213288.1 15605911 1193054 279846..282320 1 NC_000918.1 poly A polymerase 282320 pcnB1 1193054 pcnB1 Aquifex aeolicus VF5 poly A polymerase NP_213288.1 279846 D 224324 CDS NP_213289.1 15605912 1193055 282323..283039 1 NC_000918.1 ABC transporter 283039 abcT7 1193055 abcT7 Aquifex aeolicus VF5 ABC transporter NP_213289.1 282323 D 224324 CDS NP_213290.1 15605913 1193056 283036..284355 1 NC_000918.1 hypothetical protein 284355 1193056 aq_414 Aquifex aeolicus VF5 hypothetical protein NP_213290.1 283036 D 224324 CDS NP_213291.1 15605914 1193057 284327..285490 1 NC_000918.1 Na(+)/H(+) antiporter 285490 napA1 1193057 napA1 Aquifex aeolicus VF5 Na(+)/H(+) antiporter NP_213291.1 284327 D 224324 CDS NP_213292.1 15605915 1193058 285507..286553 1 NC_000918.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 286553 1193058 aq_416 Aquifex aeolicus VF5 ribosomal RNA large subunit methyltransferase N NP_213292.1 285507 D 224324 CDS NP_213293.1 15605916 1193059 286550..287209 1 NC_000918.1 ABC transporter 287209 abcT6 1193059 abcT6 Aquifex aeolicus VF5 ABC transporter NP_213293.1 286550 D 224324 CDS NP_213294.1 15605917 1193060 complement(287456..287857) 1 NC_000918.1 general secretion pathway protein G 287857 gspG 1193060 gspG Aquifex aeolicus VF5 general secretion pathway protein G NP_213294.1 287456 R 224324 CDS NP_213295.1 15605918 1193061 complement(287857..288189) 1 NC_000918.1 hypothetical protein 288189 1193061 aq_419 Aquifex aeolicus VF5 hypothetical protein NP_213295.1 287857 R 224324 CDS NP_213296.1 15605919 1193062 complement(288189..288536) 1 NC_000918.1 hypothetical protein 288536 1193062 aq_420 Aquifex aeolicus VF5 hypothetical protein NP_213296.1 288189 R 224324 CDS NP_213297.1 15605920 1193063 288568..289689 1 NC_000918.1 aminotransferase 289689 aspC3 1193063 aspC3 Aquifex aeolicus VF5 aminotransferase NP_213297.1 288568 D 224324 CDS NP_213298.1 15605921 1193064 289705..290040 1 NC_000918.1 methionyl-tRNA synthetase subunit beta 290040 metG' 1193064 metG' Aquifex aeolicus VF5 methionyl-tRNA synthetase subunit beta NP_213298.1 289705 D 224324 CDS NP_213299.1 15605922 1193065 290037..290654 1 NC_000918.1 hypothetical protein 290654 1193065 aq_423 Aquifex aeolicus VF5 hypothetical protein NP_213299.1 290037 D 224324 CDS NP_213300.1 15605923 1193066 complement(290643..291701) 1 NC_000918.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 291701 thrC2 1193066 thrC2 Aquifex aeolicus VF5 threonine synthase NP_213300.1 290643 R 224324 CDS NP_213301.1 15605924 1193067 complement(291728..292093) 1 NC_000918.1 hypothetical protein 292093 1193067 aq_427 Aquifex aeolicus VF5 hypothetical protein NP_213301.1 291728 R 224324 CDS NP_213302.1 15605925 1193068 complement(292111..292557) 1 NC_000918.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 292557 1193068 aq_428 Aquifex aeolicus VF5 D-tyrosyl-tRNA(Tyr) deacylase NP_213302.1 292111 R 224324 CDS YP_008920729.1 566344049 17925348 complement(292559..292801) 1 NC_000918.1 hypothetical protein 292801 17925348 aq_427a Aquifex aeolicus VF5 hypothetical protein YP_008920729.1 292559 R 224324 CDS NP_213303.1 15605926 1193069 292832..293572 1 NC_000918.1 hypothetical protein 293572 1193069 aq_429 Aquifex aeolicus VF5 hypothetical protein NP_213303.1 292832 D 224324 CDS NP_213304.1 15605927 1193070 complement(293549..294100) 1 NC_000918.1 hypothetical protein 294100 1193070 aq_430 Aquifex aeolicus VF5 hypothetical protein NP_213304.1 293549 R 224324 CDS NP_213305.1 15605928 1193071 complement(294248..294796) 1 NC_000918.1 heat shock protein GrpE 294796 grpE 1193071 grpE Aquifex aeolicus VF5 heat shock protein GrpE NP_213305.1 294248 R 224324 CDS NP_213306.1 15605929 1193072 complement(294816..296294) 1 NC_000918.1 glycerol kinase 296294 glpK 1193072 glpK Aquifex aeolicus VF5 glycerol kinase NP_213306.1 294816 R 224324 CDS NP_213307.1 15605930 1193073 complement(296291..296965) 1 NC_000918.1 riboflavin specific deaminase 296965 ribD2 1193073 ribD2 Aquifex aeolicus VF5 riboflavin specific deaminase NP_213307.1 296291 R 224324 CDS NP_213308.1 15605931 1193074 297105..299003 1 NC_000918.1 NADH dehydrogenase I subunit G 299003 nuoG 1193074 nuoG Aquifex aeolicus VF5 NADH dehydrogenase I subunit G NP_213308.1 297105 D 224324 CDS NP_213311.1 15605934 1193077 300870..301664 1 NC_000918.1 hypothetical protein 301664 1193077 aq_440 Aquifex aeolicus VF5 hypothetical protein NP_213311.1 300870 D 224324 CDS NP_213312.1 15605935 1193078 complement(301661..302320) 1 NC_000918.1 hypothetical protein 302320 1193078 aq_442 Aquifex aeolicus VF5 hypothetical protein NP_213312.1 301661 R 224324 CDS NP_213313.1 15605936 1193079 302447..303136 1 NC_000918.1 glutaredoxin-like protein 303136 gua 1193079 gua Aquifex aeolicus VF5 glutaredoxin-like protein NP_213313.1 302447 D 224324 CDS NP_213314.1 15605937 1193080 303136..303966 1 NC_000918.1 acetyl-CoA carboxyltransferase subunit beta 303966 accD 1193080 accD Aquifex aeolicus VF5 acetyl-CoA carboxyltransferase subunit beta NP_213314.1 303136 D 224324 CDS NP_213315.1 15605938 1193081 303963..304640 1 NC_000918.1 Mg(2+) transport ATPase 304640 mgtC 1193081 mgtC Aquifex aeolicus VF5 Mg(2+) transport ATPase NP_213315.1 303963 D 224324 CDS NP_213316.1 15605939 1193082 304651..304941 1 NC_000918.1 hypothetical protein 304941 1193082 aq_448 Aquifex aeolicus VF5 hypothetical protein NP_213316.1 304651 D 224324 CDS NP_213317.1 15605940 1193083 304932..305306 1 NC_000918.1 hypothetical protein 305306 1193083 aq_449 Aquifex aeolicus VF5 hypothetical protein NP_213317.1 304932 D 224324 CDS NP_213318.1 15605941 1193084 305303..305620 1 NC_000918.1 hypothetical protein 305620 1193084 aq_450 Aquifex aeolicus VF5 hypothetical protein NP_213318.1 305303 D 224324 CDS NP_213319.1 15605942 1193085 complement(305617..307374) 1 NC_000918.1 acetolactate synthase large subunit 307374 ilvB 1193085 ilvB Aquifex aeolicus VF5 acetolactate synthase large subunit NP_213319.1 305617 R 224324 CDS NP_213320.1 15605943 1193086 complement(307708..308481) 1 NC_000918.1 hypothetical protein 308481 1193086 aq_453 Aquifex aeolicus VF5 hypothetical protein NP_213320.1 307708 R 224324 CDS NP_213321.1 15605944 1193087 complement(308469..309581) 1 NC_000918.1 hypothetical protein 309581 1193087 aq_454 Aquifex aeolicus VF5 hypothetical protein NP_213321.1 308469 R 224324 CDS NP_213322.1 15605945 1193088 complement(309613..310614) 1 NC_000918.1 sulfur oxygenase reductase 310614 sor 1193088 sor Aquifex aeolicus VF5 sulfur oxygenase reductase NP_213322.1 309613 R 224324 CDS NP_213323.1 15605946 1193089 310732..311235 1 NC_000918.1 bacterioferritin comigratory protein 311235 bcp 1193089 bcp Aquifex aeolicus VF5 bacterioferritin comigratory protein NP_213323.1 310732 D 224324 CDS NP_213324.1 15605947 1193090 311258..311782 1 NC_000918.1 hypothetical protein 311782 1193090 aq_459 Aquifex aeolicus VF5 hypothetical protein NP_213324.1 311258 D 224324 CDS NP_213325.1 15605948 1193091 311779..312390 1 NC_000918.1 hypothetical protein 312390 1193091 aq_460 Aquifex aeolicus VF5 hypothetical protein NP_213325.1 311779 D 224324 CDS NP_213326.1 15605949 1193092 312402..313838 1 NC_000918.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 313838 gatB 1193092 gatB Aquifex aeolicus VF5 aspartyl/glutamyl-tRNA amidotransferase subunit B NP_213326.1 312402 D 224324 CDS NP_213327.1 15605950 1193093 313851..314192 1 NC_000918.1 hypothetical protein 314192 1193093 aq_465 Aquifex aeolicus VF5 hypothetical protein NP_213327.1 313851 D 224324 CDS NP_213328.1 15605951 1193186 314640..315419 1 NC_000918.1 hypothetical protein 315419 1193186 aq_467 Aquifex aeolicus VF5 hypothetical protein NP_213328.1 314640 D 224324 CDS NP_213329.1 15605952 1193187 315416..316495 1 NC_000918.1 cation efflux system CzcB-like protein 316495 czcB3 1193187 czcB3 Aquifex aeolicus VF5 cation efflux system CzcB-like protein NP_213329.1 315416 D 224324 CDS NP_213330.1 15605953 1193188 316510..319569 1 NC_000918.1 AcrB/AcrD/AcrF family cation efflux protein 319569 acrD3 1193188 acrD3 Aquifex aeolicus VF5 AcrB/AcrD/AcrF family cation efflux protein NP_213330.1 316510 D 224324 CDS NP_213331.1 15605954 1193189 319586..320233 1 NC_000918.1 hypothetical protein 320233 1193189 aq_473 Aquifex aeolicus VF5 hypothetical protein NP_213331.1 319586 D 224324 CDS NP_213332.1 15605955 1193190 complement(320225..321457) 1 NC_000918.1 hypothetical protein 321457 1193190 aq_474 Aquifex aeolicus VF5 hypothetical protein NP_213332.1 320225 R 224324 CDS NP_213333.1 15605956 1193191 322201..322575 1 NC_000918.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 322575 panD 1193191 panD Aquifex aeolicus VF5 aspartate alpha-decarboxylase NP_213333.1 322201 D 224324 CDS NP_213334.1 15605957 1193192 322577..322909 1 NC_000918.1 hypothetical protein 322909 1193192 aq_477 Aquifex aeolicus VF5 hypothetical protein NP_213334.1 322577 D 224324 CDS NP_213335.1 15605958 1193193 complement(322899..324134) 1 NC_000918.1 hypothetical protein 324134 1193193 aq_478 Aquifex aeolicus VF5 hypothetical protein NP_213335.1 322899 R 224324 CDS NP_213336.1 15605959 1193194 complement(324100..325386) 1 NC_000918.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 325386 glyA 1193194 glyA Aquifex aeolicus VF5 serine hydroxymethyltransferase NP_213336.1 324100 R 224324 CDS NP_213337.1 15605960 1193195 complement(325395..326378) 1 NC_000918.1 transporter 326378 oppB 1193195 oppB Aquifex aeolicus VF5 transporter NP_213337.1 325395 R 224324 CDS NP_213338.1 15605961 1193196 326762..328042 1 NC_000918.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 328042 eno 1193196 eno Aquifex aeolicus VF5 phosphopyruvate hydratase NP_213338.1 326762 D 224324 CDS NP_213339.1 15605962 1193197 complement(328330..328965) 1 NC_000918.1 alkyl hydroperoxide reductase 328965 ahpC1 1193197 ahpC1 Aquifex aeolicus VF5 alkyl hydroperoxide reductase NP_213339.1 328330 R 224324 CDS NP_213340.1 15605963 1193198 complement(329019..329528) 1 NC_000918.1 thiol peroxidase 329528 tpx 1193198 tpx Aquifex aeolicus VF5 thiol peroxidase NP_213340.1 329019 R 224324 CDS NP_213341.1 15605964 1193199 complement(329597..330319) 1 NC_000918.1 Crp family transcriptional regulator 330319 fnr 1193199 fnr Aquifex aeolicus VF5 Crp family transcriptional regulator NP_213341.1 329597 R 224324 CDS NP_213345.1 15605968 1193203 332980..333465 1 NC_000918.1 hypothetical protein 333465 1193203 aq_495 Aquifex aeolicus VF5 hypothetical protein NP_213345.1 332980 D 224324 CDS NP_213346.1 15605969 1193204 333390..334088 1 NC_000918.1 endonuclease III 334088 mutY3 1193204 mutY3 Aquifex aeolicus VF5 endonuclease III NP_213346.1 333390 D 224324 CDS NP_213347.1 15605970 1193205 complement(334072..335367) 1 NC_000918.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 335367 gsdA 1193205 gsdA Aquifex aeolicus VF5 glucose-6-phosphate 1-dehydrogenase NP_213347.1 334072 R 224324 CDS NP_213348.1 15605971 1193206 complement(335330..336232) 1 NC_000918.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 336232 gnd 1193206 gnd Aquifex aeolicus VF5 6-phosphogluconate dehydrogenase NP_213348.1 335330 R 224324 CDS NP_213349.1 15605972 1193207 complement(336232..337032) 1 NC_000918.1 hypothetical protein 337032 1193207 aq_499 Aquifex aeolicus VF5 hypothetical protein NP_213349.1 336232 R 224324 CDS NP_213350.1 15605973 1193208 complement(337114..338085) 1 NC_000918.1 thioredoxin reductase 338085 trxB 1193208 trxB Aquifex aeolicus VF5 thioredoxin reductase NP_213350.1 337114 R 224324 CDS NP_213351.1 15605974 1193209 complement(338228..339727) 1 NC_000918.1 phosphoglucomutase/phosphomannomutase 339727 pmu 1193209 pmu Aquifex aeolicus VF5 phosphoglucomutase/phosphomannomutase NP_213351.1 338228 R 224324 CDS NP_213352.1 15605975 1193210 complement(339619..340080) 1 NC_000918.1 hypothetical protein 340080 1193210 aq_503 Aquifex aeolicus VF5 hypothetical protein NP_213352.1 339619 R 224324 CDS NP_213353.1 15605976 1193211 complement(340164..340583) 1 NC_000918.1 polysaccharide biosynthesis protein (fragment) 340583 otnA' 1193211 otnA' Aquifex aeolicus VF5 polysaccharide biosynthesis protein (fragment) NP_213353.1 340164 R 224324 CDS NP_213354.1 15605977 1193212 complement(340614..342791) 1 NC_000918.1 polysaccharide biosynthesis protein 342791 otnA 1193212 otnA Aquifex aeolicus VF5 polysaccharide biosynthesis protein NP_213354.1 340614 R 224324 CDS NP_213355.1 15605978 1193213 complement(342733..344034) 1 NC_000918.1 hypothetical protein 344034 1193213 aq_506 Aquifex aeolicus VF5 hypothetical protein NP_213355.1 342733 R 224324 CDS NP_213356.2 566344046 1193214 344006..344278 1 NC_000918.1 hypothetical protein 344278 1193214 aq_507 Aquifex aeolicus VF5 hypothetical protein NP_213356.2 344006 D 224324 CDS NP_213357.1 15605980 1193215 345070..346395 1 NC_000918.1 hypothetical protein 346395 1193215 aq_509 Aquifex aeolicus VF5 hypothetical protein NP_213357.1 345070 D 224324 CDS NP_213358.1 15605981 1193216 346396..346866 1 NC_000918.1 hypothetical protein 346866 1193216 aq_510 Aquifex aeolicus VF5 hypothetical protein NP_213358.1 346396 D 224324 CDS NP_213359.1 15605982 1193217 346905..347546 1 NC_000918.1 UDP-N-acetoenolpyruvoylglucosamine reductase 347546 murB2 1193217 murB2 Aquifex aeolicus VF5 UDP-N-acetoenolpyruvoylglucosamine reductase NP_213359.1 346905 D 224324 CDS NP_213360.1 15605983 1193218 complement(347383..348366) 1 NC_000918.1 hypothetical protein 348366 1193218 aq_512 Aquifex aeolicus VF5 hypothetical protein NP_213360.1 347383 R 224324 CDS NP_213361.1 15605984 1193219 349447..350571 1 NC_000918.1 mannosyltransferase B 350571 mtfB 1193219 mtfB Aquifex aeolicus VF5 mannosyltransferase B NP_213361.1 349447 D 224324 CDS NP_213362.1 15605985 1193220 350568..351674 1 NC_000918.1 mannosyltransferase C 351674 mtfC 1193220 mtfC Aquifex aeolicus VF5 mannosyltransferase C NP_213362.1 350568 D 224324 CDS NP_213363.1 15605986 1193221 351738..352151 1 NC_000918.1 spore coat polysaccharide biosynthesis protein SpsK 352151 spsK 1193221 spsK Aquifex aeolicus VF5 spore coat polysaccharide biosynthesis protein SpsK NP_213363.1 351738 D 224324 CDS NP_213364.1 15605987 1193222 352120..353193 1 NC_000918.1 UDP-phosphate-alpha-N- acetylglucosaminyltransferase 353193 rfe 1193222 rfe Aquifex aeolicus VF5 UDP-phosphate-alpha-N- acetylglucosaminyltransferase NP_213364.1 352120 D 224324 CDS NP_213365.1 15605988 1193223 353194..354087 1 NC_000918.1 UDP-N-acetylenolpyruvoylglucosamine reductase 354087 murB1 1193223 murB1 Aquifex aeolicus VF5 UDP-N-acetylenolpyruvoylglucosamine reductase NP_213365.1 353194 D 224324 CDS NP_213366.1 15605989 1193224 354044..354919 1 NC_000918.1 D-alanine--D-alanine ligase 354919 ddlA 1193224 ddlA Aquifex aeolicus VF5 D-alanine--D-alanine ligase NP_213366.1 354044 D 224324 CDS NP_213367.1 15605990 1193225 354930..355580 1 NC_000918.1 hypothetical protein 355580 1193225 aq_522 Aquifex aeolicus VF5 hypothetical protein NP_213367.1 354930 D 224324 CDS NP_213368.1 15605991 1193226 355580..356830 1 NC_000918.1 cell division protein FtsA 356830 ftsA 1193226 ftsA Aquifex aeolicus VF5 cell division protein FtsA NP_213368.1 355580 D 224324 CDS NP_213369.1 15605992 1193227 356843..357946 1 NC_000918.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 357946 ftsZ 1193227 ftsZ Aquifex aeolicus VF5 cell division protein FtsZ NP_213369.1 356843 D 224324 CDS NP_213370.1 15605993 1193228 357943..358707 1 NC_000918.1 molybdenum cofactor biosynthesis moaC 358707 moaC 1193228 moaC Aquifex aeolicus VF5 molybdenum cofactor biosynthesis moaC NP_213370.1 357943 D 224324 CDS NP_213371.1 15605994 1193229 358695..359264 1 NC_000918.1 phenylacrylic acid decarboxylase 359264 dedF 1193229 dedF Aquifex aeolicus VF5 phenylacrylic acid decarboxylase NP_213371.1 358695 D 224324 CDS NP_213372.1 15605995 1193230 complement(359590..361632) 1 NC_000918.1 outer membrane protein c 361632 oprC 1193230 oprC Aquifex aeolicus VF5 outer membrane protein c NP_213372.1 359590 R 224324 CDS NP_213373.1 15605996 1193231 361705..362493 1 NC_000918.1 hypothetical protein 362493 1193231 aq_531 Aquifex aeolicus VF5 hypothetical protein NP_213373.1 361705 D 224324 CDS NP_213374.1 15605997 1193232 complement(362461..363126) 1 NC_000918.1 hypothetical protein 363126 1193232 aq_532 Aquifex aeolicus VF5 hypothetical protein NP_213374.1 362461 R 224324 CDS NP_213375.1 15605998 1193233 complement(363142..364284) 1 NC_000918.1 hypothetical protein 364284 1193233 aq_533 Aquifex aeolicus VF5 hypothetical protein NP_213375.1 363142 R 224324 CDS NP_213376.1 15605999 1193234 364314..365306 1 NC_000918.1 ADP-ribosylglycohydrolase 365306 draG 1193234 draG Aquifex aeolicus VF5 ADP-ribosylglycohydrolase NP_213376.1 364314 D 224324 CDS NP_213378.1 15606001 1193236 366297..367154 1 NC_000918.1 hypothetical protein 367154 1193236 aq_539 Aquifex aeolicus VF5 hypothetical protein NP_213378.1 366297 D 224324 CDS NP_213379.1 15606002 1193237 complement(367143..367787) 1 NC_000918.1 hypothetical protein 367787 1193237 aq_540 Aquifex aeolicus VF5 hypothetical protein NP_213379.1 367143 R 224324 CDS NP_213380.1 15606003 1193238 368017..369240 1 NC_000918.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; cofactor-independent phosphoglycerate mutase 369240 bcpC 1193238 bcpC Aquifex aeolicus VF5 cofactor-independent phosphoglycerate mutase NP_213380.1 368017 D 224324 CDS NP_213381.1 15606004 1193239 369242..369778 1 NC_000918.1 hypoxanthine-guanine phosphoribosyltransferase 369778 hpt 1193239 hpt Aquifex aeolicus VF5 hypoxanthine-guanine phosphoribosyltransferase NP_213381.1 369242 D 224324 CDS NP_213382.1 15606005 1193240 complement(369760..370959) 1 NC_000918.1 hypothetical protein 370959 1193240 aq_545 Aquifex aeolicus VF5 hypothetical protein NP_213382.1 369760 R 224324 CDS NP_213383.1 15606006 1193241 371023..371922 1 NC_000918.1 succinyl-diaminopimelate desuccinylase 371922 dapE 1193241 dapE Aquifex aeolicus VF5 succinyl-diaminopimelate desuccinylase NP_213383.1 371023 D 224324 CDS NP_213384.1 15606007 1193242 complement(372081..372647) 1 NC_000918.1 hypothetical protein 372647 1193242 aq_548 Aquifex aeolicus VF5 hypothetical protein NP_213384.1 372081 R 224324 CDS NP_213385.1 15606008 1193243 complement(372746..373339) 1 NC_000918.1 anthranilate synthase component II 373339 trpG 1193243 trpG Aquifex aeolicus VF5 anthranilate synthase component II NP_213385.1 372746 R 224324 CDS NP_213386.1 15606009 1193244 complement(373336..375117) 1 NC_000918.1 NADH dehydrogenase I subunit D 375117 nuoD1 1193244 nuoD1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit D NP_213386.1 373336 R 224324 CDS NP_213387.1 15606010 1193245 complement(375161..376495) 1 NC_000918.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 376495 sms 1193245 sms Aquifex aeolicus VF5 DNA repair protein RadA NP_213387.1 375161 R 224324 CDS NP_213388.1 15606011 1193246 complement(376504..377196) 1 NC_000918.1 fumarate reductase iron-sulfur subunit 377196 frdB1 1193246 frdB1 Aquifex aeolicus VF5 fumarate reductase iron-sulfur subunit NP_213388.1 376504 R 224324 CDS NP_213389.1 15606012 1193247 complement(377232..377948) 1 NC_000918.1 hypothetical protein 377948 1193247 aq_554 Aquifex aeolicus VF5 hypothetical protein NP_213389.1 377232 R 224324 CDS NP_213390.1 15606013 1193248 377884..378687 1 NC_000918.1 hypothetical protein 378687 1193248 aq_555 Aquifex aeolicus VF5 hypothetical protein NP_213390.1 377884 D 224324 CDS NP_213391.1 15606014 1193249 378689..380425 1 NC_000918.1 penicillin binding protein 2 380425 pbpA2 1193249 pbpA2 Aquifex aeolicus VF5 penicillin binding protein 2 NP_213391.1 378689 D 224324 CDS NP_213392.1 15606015 1193250 complement(380398..381060) 1 NC_000918.1 dethiobiotin synthetase 381060 bioD 1193250 bioD Aquifex aeolicus VF5 dethiobiotin synthetase NP_213392.1 380398 R 224324 CDS NP_213393.1 15606016 1193251 complement(381057..381704) 1 NC_000918.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 381704 thiE 1193251 thiE Aquifex aeolicus VF5 thiamine-phosphate pyrophosphorylase NP_213393.1 381057 R 224324 CDS NP_213394.1 15606017 1193252 complement(381742..383304) 1 NC_000918.1 recombination protein RecN 383304 recN 1193252 recN Aquifex aeolicus VF5 recombination protein RecN NP_213394.1 381742 R 224324 CDS NP_213395.1 15606018 1193253 383468..385324 1 NC_000918.1 hypothetical protein 385324 1193253 aq_563 Aquifex aeolicus VF5 hypothetical protein NP_213395.1 383468 D 224324 CDS NP_213396.1 15606019 1193254 385335..386282 1 NC_000918.1 ADP-heptose synthase 386282 rfaE 1193254 rfaE Aquifex aeolicus VF5 ADP-heptose synthase NP_213396.1 385335 D 224324 CDS NP_213397.1 15606020 1193255 386285..386986 1 NC_000918.1 biotin [acetyl-CoA-carboxylase] ligase 386986 birA 1193255 birA Aquifex aeolicus VF5 biotin [acetyl-CoA-carboxylase] ligase NP_213397.1 386285 D 224324 CDS NP_213398.1 15606021 1193256 complement(386954..387418) 1 NC_000918.1 ribosomal-protein-alanine acetyltransferase 387418 rimI 1193256 rimI Aquifex aeolicus VF5 ribosomal-protein-alanine acetyltransferase NP_213398.1 386954 R 224324 CDS NP_213399.1 15606022 1193257 387432..388265 1 NC_000918.1 purine nucleoside phosphorylase 388265 deoD 1193257 deoD Aquifex aeolicus VF5 purine nucleoside phosphorylase NP_213399.1 387432 D 224324 CDS NP_213400.1 15606023 1193258 complement(388545..389645) 1 NC_000918.1 hypothetical protein 389645 1193258 aq_572 Aquifex aeolicus VF5 hypothetical protein NP_213400.1 388545 R 224324 CDS NP_213401.1 15606024 1193259 complement(389655..390935) 1 NC_000918.1 NADH dehydrogenase I subunit F 390935 nuoF 1193259 nuoF Aquifex aeolicus VF5 NADH dehydrogenase I subunit F NP_213401.1 389655 R 224324 CDS NP_213402.1 15606025 1193260 complement(390910..391392) 1 NC_000918.1 NADH dehydrogenase I subunit E 391392 nuoE 1193260 nuoE Aquifex aeolicus VF5 NADH dehydrogenase I subunit E NP_213402.1 390910 R 224324 CDS NP_213403.1 15606026 1193261 complement(391412..392047) 1 NC_000918.1 hypothetical protein 392047 1193261 aq_575 Aquifex aeolicus VF5 hypothetical protein NP_213403.1 391412 R 224324 CDS NP_213404.1 15606027 1193262 complement(392044..392859) 1 NC_000918.1 Ser/thr protein kinase 392859 stpK 1193262 stpK Aquifex aeolicus VF5 Ser/thr protein kinase NP_213404.1 392044 R 224324 CDS NP_213405.1 15606028 1193263 392890..393504 1 NC_000918.1 hypothetical protein 393504 1193263 aq_577 Aquifex aeolicus VF5 hypothetical protein NP_213405.1 392890 D 224324 CDS NP_213406.1 15606029 1193264 complement(393496..394074) 1 NC_000918.1 hypothetical protein 394074 1193264 aq_578 Aquifex aeolicus VF5 hypothetical protein NP_213406.1 393496 R 224324 CDS NP_213407.1 15606030 1193265 394092..394601 1 NC_000918.1 polypeptide deformylase 394601 def 1193265 def Aquifex aeolicus VF5 polypeptide deformylase NP_213407.1 394092 D 224324 CDS NP_213408.1 15606031 1193266 394598..395125 1 NC_000918.1 hypothetical protein 395125 1193266 aq_581 Aquifex aeolicus VF5 hypothetical protein NP_213408.1 394598 D 224324 CDS NP_213409.1 15606032 1193267 complement(395126..396610) 1 NC_000918.1 anthranilate synthase component I 396610 trpE 1193267 trpE Aquifex aeolicus VF5 anthranilate synthase component I NP_213409.1 395126 R 224324 CDS NP_213410.1 15606033 1193268 397306..399423 1 NC_000918.1 hypothetical protein 399423 1193268 aq_585 Aquifex aeolicus VF5 hypothetical protein NP_213410.1 397306 D 224324 CDS NP_213411.1 15606034 1193269 complement(399420..400712) 1 NC_000918.1 N-ethylammeline chlorohydrolase 400712 neaC 1193269 neaC Aquifex aeolicus VF5 N-ethylammeline chlorohydrolase NP_213411.1 399420 R 224324 CDS NP_213412.1 15606035 1193270 400746..402107 1 NC_000918.1 mannose-6-phosphate isomerase/mannose-1-phosphate guanyl transferase 402107 xanB 1193270 xanB Aquifex aeolicus VF5 mannose-6-phosphate isomerase/mannose-1-phosphate guanyl transferase NP_213412.1 400746 D 224324 CDS NP_213413.1 15606036 1193271 402088..403089 1 NC_000918.1 hypothetical protein 403089 1193271 aq_591 Aquifex aeolicus VF5 hypothetical protein NP_213413.1 402088 D 224324 CDS NP_213414.1 15606037 1193272 403186..404499 1 NC_000918.1 hypothetical protein 404499 1193272 aq_592 Aquifex aeolicus VF5 hypothetical protein NP_213414.1 403186 D 224324 CDS NP_213415.1 15606038 1193273 complement(404496..406211) 1 NC_000918.1 fumarate reductase flavoprotein subunit 406211 frdA 1193273 frdA Aquifex aeolicus VF5 fumarate reductase flavoprotein subunit NP_213415.1 404496 R 224324 CDS NP_213416.1 15606039 1193274 complement(406507..407820) 1 NC_000918.1 adenylosuccinate lyase 407820 purB 1193274 purB Aquifex aeolicus VF5 adenylosuccinate lyase NP_213416.1 406507 R 224324 CDS NP_213417.1 15606040 1193275 complement(407862..408254) 1 NC_000918.1 hypothetical protein 408254 1193275 aq_598 Aquifex aeolicus VF5 hypothetical protein NP_213417.1 407862 R 224324 CDS NP_213418.1 15606041 1193276 408354..409550 1 NC_000918.1 RNA polymerase sigma factor RpoN 409550 rpoN 1193276 rpoN Aquifex aeolicus VF5 RNA polymerase sigma factor RpoN NP_213418.1 408354 D 224324 CDS NP_213419.1 15606042 1193277 complement(409567..410049) 1 NC_000918.1 hypothetical protein 410049 1193277 aq_600 Aquifex aeolicus VF5 hypothetical protein NP_213419.1 409567 R 224324 CDS NP_213420.1 15606043 1193922 410406..410942 1 NC_000918.1 hypothetical protein 410942 1193922 aq_601 Aquifex aeolicus VF5 hypothetical protein NP_213420.1 410406 D 224324 CDS NP_213421.1 15606044 1193923 411154..411972 1 NC_000918.1 hypothetical protein 411972 1193923 aq_603 Aquifex aeolicus VF5 hypothetical protein NP_213421.1 411154 D 224324 CDS NP_213422.1 15606045 1193924 412006..412791 1 NC_000918.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 412791 lpxA 1193924 lpxA Aquifex aeolicus VF5 UDP-N-acetylglucosamine acyltransferase NP_213422.1 412006 D 224324 CDS NP_213423.1 15606046 1193925 412805..414199 1 NC_000918.1 UDP-N-acetylglucosamine pyrophosphorylase 414199 glmU 1193925 glmU Aquifex aeolicus VF5 UDP-N-acetylglucosamine pyrophosphorylase NP_213423.1 412805 D 224324 CDS NP_213424.1 15606047 1193926 complement(414196..415425) 1 NC_000918.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 415425 thrC1 1193926 thrC1 Aquifex aeolicus VF5 threonine synthase NP_213424.1 414196 R 224324 CDS NP_213425.1 15606048 1193927 complement(415436..416548) 1 NC_000918.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 416548 1193927 aq_609 Aquifex aeolicus VF5 GTP-dependent nucleic acid-binding protein EngD NP_213425.1 415436 R 224324 CDS NP_213427.1 15606050 1193929 418639..419037 1 NC_000918.1 hypothetical protein 419037 1193929 aq_615 Aquifex aeolicus VF5 hypothetical protein NP_213427.1 418639 D 224324 CDS NP_213428.1 15606051 1193930 419071..419574 1 NC_000918.1 hypothetical protein 419574 1193930 aq_616 Aquifex aeolicus VF5 hypothetical protein NP_213428.1 419071 D 224324 CDS NP_213429.1 15606052 1193931 419585..420088 1 NC_000918.1 protease I 420088 pfpI 1193931 pfpI Aquifex aeolicus VF5 protease I NP_213429.1 419585 D 224324 CDS NP_213430.1 15606053 1193932 420088..420924 1 NC_000918.1 adhesion B 420924 yfeA 1193932 yfeA Aquifex aeolicus VF5 adhesion B NP_213430.1 420088 D 224324 CDS NP_213431.1 15606054 1193933 420915..421613 1 NC_000918.1 ABC transporter 421613 abcT2 1193933 abcT2 Aquifex aeolicus VF5 ABC transporter NP_213431.1 420915 D 224324 CDS NP_213433.1 15606056 1193935 complement(422376..423338) 1 NC_000918.1 hypothetical protein 423338 1193935 aq_622 Aquifex aeolicus VF5 hypothetical protein NP_213433.1 422376 R 224324 CDS NP_213434.1 15606057 1193936 423373..425553 1 NC_000918.1 penicillin binding protein 1A 425553 mrcA 1193936 mrcA Aquifex aeolicus VF5 penicillin binding protein 1A NP_213434.1 423373 D 224324 CDS NP_213435.1 15606058 1193937 425550..426671 1 NC_000918.1 8-amino-7-oxononanoate synthase 426671 bioF 1193937 bioF Aquifex aeolicus VF5 8-amino-7-oxononanoate synthase NP_213435.1 425550 D 224324 CDS NP_213436.1 15606059 1193938 complement(426668..427594) 1 NC_000918.1 hypothetical protein 427594 1193938 aq_627 Aquifex aeolicus VF5 hypothetical protein NP_213436.1 426668 R 224324 CDS NP_213437.1 15606060 1193939 complement(427634..428011) 1 NC_000918.1 hypothetical protein 428011 1193939 aq_628 Aquifex aeolicus VF5 hypothetical protein NP_213437.1 427634 R 224324 CDS YP_008920730.1 566344050 17925349 428194..428469 1 NC_000918.1 MoaD family protein 428469 17925349 aq_628a Aquifex aeolicus VF5 MoaD family protein YP_008920730.1 428194 D 224324 CDS NP_213438.1 15606061 1193940 complement(428466..431936) 1 NC_000918.1 chromosome assembly protein 431936 xcpC 1193940 xcpC Aquifex aeolicus VF5 chromosome assembly protein NP_213438.1 428466 R 224324 CDS NP_213439.1 15606062 1193941 complement(432190..433143) 1 NC_000918.1 hypothetical protein 433143 1193941 aq_632 Aquifex aeolicus VF5 hypothetical protein NP_213439.1 432190 R 224324 CDS NP_213440.1 15606063 1193942 433166..435328 1 NC_000918.1 DNA ligase 435328 ligA 1193942 ligA Aquifex aeolicus VF5 DNA ligase NP_213440.1 433166 D 224324 CDS NP_213441.1 15606064 1193943 complement(435320..435748) 1 NC_000918.1 hypothetical protein 435748 1193943 aq_635 Aquifex aeolicus VF5 hypothetical protein NP_213441.1 435320 R 224324 CDS NP_213442.1 15606065 1193944 complement(436576..437487) 1 NC_000918.1 LysR family transcriptional regulator 437487 lysR1 1193944 lysR1 Aquifex aeolicus VF5 LysR family transcriptional regulator NP_213442.1 436576 R 224324 CDS NP_213443.1 15606066 1193945 438038..438991 1 NC_000918.1 thymidylate synthase complementing protein 438991 thy 1193945 thy Aquifex aeolicus VF5 thymidylate synthase complementing protein NP_213443.1 438038 D 224324 CDS NP_213444.1 15606067 1193946 complement(439003..440085) 1 NC_000918.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 440085 1193946 aq_642 Aquifex aeolicus VF5 RNA 3'-terminal-phosphate cyclase NP_213444.1 439003 R 224324 CDS NP_213445.1 15606068 1193947 complement(440091..440774) 1 NC_000918.1 hypothetical protein 440774 1193947 aq_644 Aquifex aeolicus VF5 hypothetical protein NP_213445.1 440091 R 224324 CDS NP_213446.1 15606069 1193948 440821..442143 1 NC_000918.1 hypothetical protein 442143 1193948 aq_645 Aquifex aeolicus VF5 hypothetical protein NP_213446.1 440821 D 224324 CDS NP_213447.1 15606070 1193949 442506..443915 1 NC_000918.1 hypothetical protein 443915 1193949 aq_647 Aquifex aeolicus VF5 hypothetical protein NP_213447.1 442506 D 224324 CDS NP_213448.1 15606071 1193950 444064..445179 1 NC_000918.1 hypothetical protein 445179 1193950 aq_648 Aquifex aeolicus VF5 hypothetical protein NP_213448.1 444064 D 224324 CDS NP_213449.1 15606072 1193951 complement(445163..445759) 1 NC_000918.1 hypothetical protein 445759 1193951 aq_651 Aquifex aeolicus VF5 hypothetical protein NP_213449.1 445163 R 224324 CDS NP_213450.1 15606073 1193952 complement(445756..446805) 1 NC_000918.1 lipoprotein 446805 nlpD1 1193952 nlpD1 Aquifex aeolicus VF5 lipoprotein NP_213450.1 445756 R 224324 CDS NP_213451.1 15606074 1193953 complement(447062..448048) 1 NC_000918.1 flagellar switch protein FliG 448048 fliG 1193953 fliG Aquifex aeolicus VF5 flagellar switch protein FliG NP_213451.1 447062 R 224324 CDS NP_213452.1 15606075 1193954 complement(448050..448742) 1 NC_000918.1 fumarate reductase iron-sulfur subunit 448742 frdB2 1193954 frdB2 Aquifex aeolicus VF5 fumarate reductase iron-sulfur subunit NP_213452.1 448050 R 224324 CDS NP_213453.1 15606076 1193955 448782..450404 1 NC_000918.1 topoisomerase I 450404 topA 1193955 topA Aquifex aeolicus VF5 topoisomerase I NP_213453.1 448782 D 224324 CDS NP_213454.1 15606077 1193956 450916..451977 1 NC_000918.1 hydrogenase small subunit 451977 mbhS1 1193956 mbhS1 Aquifex aeolicus VF5 hydrogenase small subunit NP_213454.1 450916 D 224324 CDS NP_213455.1 15606078 1193957 451992..453893 1 NC_000918.1 hydrogenase large subunit 453893 mbhL1 1193957 mbhL1 Aquifex aeolicus VF5 hydrogenase large subunit NP_213455.1 451992 D 224324 CDS NP_213456.1 15606079 1193958 453886..454572 1 NC_000918.1 Ni/Fe hydrogenase B-type cytochrome subunit 454572 hoxZ 1193958 hoxZ Aquifex aeolicus VF5 Ni/Fe hydrogenase B-type cytochrome subunit NP_213456.1 453886 D 224324 CDS NP_213457.1 15606080 1193959 454585..455127 1 NC_000918.1 HupE hydrogenase related function 455127 hupE 1193959 hupE Aquifex aeolicus VF5 HupE hydrogenase related function NP_213457.1 454585 D 224324 CDS NP_213458.1 15606081 1193960 455140..455628 1 NC_000918.1 HupD hydrogenase related function 455628 hupD 1193960 hupD Aquifex aeolicus VF5 HupD hydrogenase related function NP_213458.1 455140 D 224324 CDS NP_213459.1 15606082 1193961 455615..455953 1 NC_000918.1 hypothetical protein 455953 1193961 aq_668 Aquifex aeolicus VF5 hypothetical protein NP_213459.1 455615 D 224324 CDS NP_213460.1 15606083 1193962 455947..456342 1 NC_000918.1 hypothetical protein 456342 1193962 aq_669 Aquifex aeolicus VF5 hypothetical protein NP_213460.1 455947 D 224324 CDS NP_213461.1 15606084 1193963 456335..457114 1 NC_000918.1 hydrogenase expression/formation protein B 457114 hypB 1193963 hypB Aquifex aeolicus VF5 hydrogenase expression/formation protein B NP_213461.1 456335 D 224324 CDS NP_213462.1 15606085 1193964 457083..459323 1 NC_000918.1 transcriptional regulatory protein HypF 459323 hypF 1193964 hypF Aquifex aeolicus VF5 transcriptional regulatory protein HypF NP_213462.1 457083 D 224324 CDS NP_213463.1 15606086 1193965 459334..459732 1 NC_000918.1 ATP synthase F1 subunit epsilon 459732 atpC 1193965 atpC Aquifex aeolicus VF5 ATP synthase F1 subunit epsilon NP_213463.1 459334 D 224324 CDS NP_213464.1 15606087 1193966 459716..460435 1 NC_000918.1 hypothetical protein 460435 1193966 aq_674 Aquifex aeolicus VF5 hypothetical protein NP_213464.1 459716 D 224324 CDS NP_213465.1 15606088 1193967 complement(460432..461010) 1 NC_000918.1 hypothetical protein 461010 1193967 aq_676 Aquifex aeolicus VF5 hypothetical protein NP_213465.1 460432 R 224324 CDS NP_213466.1 15606089 1193968 complement(461021..461599) 1 NC_000918.1 hypothetical protein 461599 1193968 aq_678 Aquifex aeolicus VF5 hypothetical protein NP_213466.1 461021 R 224324 CDS NP_213467.1 15606090 1193969 461663..463174 1 NC_000918.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 463174 atpA 1193969 atpA Aquifex aeolicus VF5 F0F1 ATP synthase subunit alpha NP_213467.1 461663 D 224324 CDS NP_213468.1 15606091 1193970 complement(463190..464380) 1 NC_000918.1 anion transporting ATPase 464380 arsA1 1193970 arsA1 Aquifex aeolicus VF5 anion transporting ATPase NP_213468.1 463190 R 224324 CDS NP_213469.1 15606092 1193971 464435..465184 1 NC_000918.1 hypothetical protein 465184 1193971 aq_684 Aquifex aeolicus VF5 hypothetical protein NP_213469.1 464435 D 224324 CDS NP_213470.1 15606093 1193972 465181..465615 1 NC_000918.1 arsenate reductase 465615 arsC 1193972 arsC Aquifex aeolicus VF5 arsenate reductase NP_213470.1 465181 D 224324 CDS NP_213471.1 15606094 1193973 465627..468407 1 NC_000918.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 468407 uvrA 1193973 uvrA Aquifex aeolicus VF5 excinuclease ABC subunit A NP_213471.1 465627 D 224324 CDS NP_213472.1 15606095 1193974 complement(468404..469414) 1 NC_000918.1 hypothetical protein 469414 1193974 aq_689 Aquifex aeolicus VF5 hypothetical protein NP_213472.1 468404 R 224324 CDS NP_213473.1 15606096 1193975 complement(469427..470764) 1 NC_000918.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 470764 gidA2 1193975 gidA2 Aquifex aeolicus VF5 tRNA (uracil-5-)-methyltransferase Gid NP_213473.1 469427 R 224324 CDS NP_213474.1 15606097 1193976 470797..471501 1 NC_000918.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 471501 kpsU 1193976 kpsU Aquifex aeolicus VF5 3-deoxy-manno-octulosonate cytidylyltransferase NP_213474.1 470797 D 224324 CDS NP_213475.1 15606098 1193977 complement(471539..472783) 1 NC_000918.1 hypothetical protein 472783 1193977 aq_693 Aquifex aeolicus VF5 hypothetical protein NP_213475.1 471539 R 224324 CDS NP_213476.1 15606099 1193978 complement(472894..476142) 1 NC_000918.1 AcrB/AcrD/AcrF family cation efflux protein 476142 acrD1 1193978 acrD1 Aquifex aeolicus VF5 AcrB/AcrD/AcrF family cation efflux protein NP_213476.1 472894 R 224324 CDS NP_213477.1 15606100 1193979 complement(476147..477271) 1 NC_000918.1 acriflavin resistance protein AcrE 477271 acrE 1193979 acrE Aquifex aeolicus VF5 acriflavin resistance protein AcrE NP_213477.1 476147 R 224324 CDS NP_213478.1 15606101 1193980 complement(477268..478581) 1 NC_000918.1 hypothetical protein 478581 1193980 aq_699 Aquifex aeolicus VF5 hypothetical protein NP_213478.1 477268 R 224324 CDS NP_213479.1 15606102 1193981 complement(478635..479876) 1 NC_000918.1 hypothetical protein 479876 1193981 aq_701 Aquifex aeolicus VF5 hypothetical protein NP_213479.1 478635 R 224324 CDS NP_213480.1 15606103 1193982 complement(479863..480273) 1 NC_000918.1 MerR family transcriptional regulator 480273 merR 1193982 merR Aquifex aeolicus VF5 MerR family transcriptional regulator NP_213480.1 479863 R 224324 CDS NP_213481.1 15606104 1193370 complement(480279..481409) 1 NC_000918.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone DnaJ 481409 dnaJ2 1193370 dnaJ2 Aquifex aeolicus VF5 chaperone DnaJ NP_213481.1 480279 R 224324 CDS NP_213482.1 15606105 1193371 complement(481480..482343) 1 NC_000918.1 tRNA pseudouridine 55 synthase 482343 truB 1193371 truB Aquifex aeolicus VF5 tRNA pseudouridine 55 synthase NP_213482.1 481480 R 224324 CDS NP_213483.1 15606106 1193372 482374..483567 1 NC_000918.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 483567 trpB1 1193372 trpB1 Aquifex aeolicus VF5 tryptophan synthase subunit beta NP_213483.1 482374 D 224324 CDS NP_213484.1 15606107 1193373 483583..484644 1 NC_000918.1 hypothetical protein 484644 1193373 aq_707 Aquifex aeolicus VF5 hypothetical protein NP_213484.1 483583 D 224324 CDS NP_213485.1 15606108 1193374 484648..486630 1 NC_000918.1 N-methylhydantoinase A 486630 hyuA 1193374 hyuA Aquifex aeolicus VF5 N-methylhydantoinase A NP_213485.1 484648 D 224324 CDS NP_213486.1 15606109 1193375 complement(486617..487135) 1 NC_000918.1 thermococcal nuclease-like protein 487135 nucI 1193375 nucI Aquifex aeolicus VF5 thermococcal nuclease-like protein NP_213486.1 486617 R 224324 CDS NP_213487.1 15606110 1193376 complement(487132..487647) 1 NC_000918.1 hypothetical protein 487647 1193376 aq_711 Aquifex aeolicus VF5 hypothetical protein NP_213487.1 487132 R 224324 CDS NP_213488.1 15606111 1193377 complement(487644..488198) 1 NC_000918.1 ribosome recycling factor 488198 frr 1193377 frr Aquifex aeolicus VF5 ribosome recycling factor NP_213488.1 487644 R 224324 CDS NP_213489.1 15606112 1193378 complement(488204..488926) 1 NC_000918.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 488926 pyrH 1193378 pyrH Aquifex aeolicus VF5 uridylate kinase NP_213489.1 488204 R 224324 CDS NP_213490.1 15606113 1193379 complement(488926..489798) 1 NC_000918.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 489798 tsf 1193379 tsf Aquifex aeolicus VF5 elongation factor Ts NP_213490.1 488926 R 224324 CDS NP_213491.1 15606114 1193380 complement(489875..491269) 1 NC_000918.1 hypothetical protein 491269 1193380 aq_716 Aquifex aeolicus VF5 hypothetical protein NP_213491.1 489875 R 224324 CDS NP_213492.1 15606115 1193381 491380..493458 1 NC_000918.1 glycogen phosphorylase 493458 glgP 1193381 glgP Aquifex aeolicus VF5 glycogen phosphorylase NP_213492.1 491380 D 224324 CDS NP_213493.1 15606116 1193382 493455..495950 1 NC_000918.1 mannose-1-phosphate guanyltransferase 495950 mpg 1193382 mpg Aquifex aeolicus VF5 mannose-1-phosphate guanyltransferase NP_213493.1 493455 D 224324 CDS NP_213494.1 15606117 1193383 495947..497380 1 NC_000918.1 hypothetical protein 497380 1193383 aq_720 Aquifex aeolicus VF5 hypothetical protein NP_213494.1 495947 D 224324 CDS NP_213495.1 15606118 1193384 497377..498768 1 NC_000918.1 glycogen synthase 498768 glgA 1193384 glgA Aquifex aeolicus VF5 glycogen synthase NP_213495.1 497377 D 224324 CDS NP_213496.1 15606119 1193385 498743..500635 1 NC_000918.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 500635 glgB 1193385 glgB Aquifex aeolicus VF5 glycogen branching enzyme NP_213496.1 498743 D 224324 CDS NP_213497.1 15606120 1193386 500632..502089 1 NC_000918.1 4-alpha-glucanotransferase 502089 malM 1193386 malM Aquifex aeolicus VF5 4-alpha-glucanotransferase NP_213497.1 500632 D 224324 CDS NP_213498.1 15606121 1193387 502101..504608 1 NC_000918.1 cation transporter E1-E2 family ATPase 504608 ctrA1 1193387 ctrA1 Aquifex aeolicus VF5 cation transporter E1-E2 family ATPase NP_213498.1 502101 D 224324 CDS NP_213499.1 15606122 1193388 504614..505618 1 NC_000918.1 D-lactate dehydrogenase 505618 ldhA 1193388 ldhA Aquifex aeolicus VF5 D-lactate dehydrogenase NP_213499.1 504614 D 224324 CDS NP_213500.1 15606123 1193389 505654..506826 1 NC_000918.1 ornithine decarboxylase 506826 speC 1193389 speC Aquifex aeolicus VF5 ornithine decarboxylase NP_213500.1 505654 D 224324 CDS NP_213501.1 15606124 1193390 506732..507745 1 NC_000918.1 hypothetical protein 507745 1193390 aq_729 Aquifex aeolicus VF5 hypothetical protein NP_213501.1 506732 D 224324 CDS NP_213502.1 15606125 1193391 507757..508590 1 NC_000918.1 cytochrome C-type biogenesis protein 508590 ccdA 1193391 ccdA Aquifex aeolicus VF5 cytochrome C-type biogenesis protein NP_213502.1 507757 D 224324 CDS NP_213503.1 15606126 1193392 508590..509213 1 NC_000918.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 509213 hisH 1193392 hisH Aquifex aeolicus VF5 imidazole glycerol phosphate synthase subunit HisH NP_213503.1 508590 D 224324 CDS NP_213504.1 15606127 1193393 complement(509203..509685) 1 NC_000918.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 509685 rpsG2 1193393 rpsG2 Aquifex aeolicus VF5 30S ribosomal protein S7 NP_213504.1 509203 R 224324 CDS NP_213505.1 15606128 1193394 complement(509689..510075) 1 NC_000918.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 510075 rpsL 1193394 rpsL Aquifex aeolicus VF5 30S ribosomal protein S12 NP_213505.1 509689 R 224324 CDS NP_213506.1 15606129 1193395 510161..511558 1 NC_000918.1 dihydrolipoamide dehydrogenase 511558 lpdA 1193395 lpdA Aquifex aeolicus VF5 dihydrolipoamide dehydrogenase NP_213506.1 510161 D 224324 CDS NP_213507.1 15606130 1193396 511622..512716 1 NC_000918.1 hypothetical protein 512716 1193396 aq_737 Aquifex aeolicus VF5 hypothetical protein NP_213507.1 511622 D 224324 CDS NP_213508.1 15606131 1193397 512737..513957 1 NC_000918.1 FeS cluster formation protein NifS 513957 nifS2 1193397 nifS2 Aquifex aeolicus VF5 FeS cluster formation protein NifS NP_213508.1 512737 D 224324 CDS NP_213509.1 15606132 1193398 513969..515030 1 NC_000918.1 hypothetical protein 515030 1193398 aq_740 Aquifex aeolicus VF5 hypothetical protein NP_213509.1 513969 D 224324 CDS NP_213510.1 15606133 1193399 complement(515011..516285) 1 NC_000918.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 516285 purD 1193399 purD Aquifex aeolicus VF5 phosphoribosylamine--glycine ligase NP_213510.1 515011 R 224324 CDS NP_213511.1 15606134 1193400 516321..517421 1 NC_000918.1 twitching motility protein PilT 517421 pilT 1193400 pilT Aquifex aeolicus VF5 twitching motility protein PilT NP_213511.1 516321 D 224324 CDS NP_213512.1 15606135 1193401 517421..518647 1 NC_000918.1 fimbrial assembly protein PilC 518647 pilC1 1193401 pilC1 Aquifex aeolicus VF5 fimbrial assembly protein PilC NP_213512.1 517421 D 224324 CDS NP_213513.1 15606136 1193402 complement(518640..519428) 1 NC_000918.1 geranylgeranyl pyrophosphate synthase 519428 ispA 1193402 ispA Aquifex aeolicus VF5 geranylgeranyl pyrophosphate synthase NP_213513.1 518640 R 224324 CDS NP_213514.1 15606137 1193403 complement(519442..520167) 1 NC_000918.1 pseudouridine synthase I 520167 truA 1193403 truA Aquifex aeolicus VF5 pseudouridine synthase I NP_213514.1 519442 R 224324 CDS NP_213515.1 15606138 1193404 complement(520160..521122) 1 NC_000918.1 catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate; bifunctional phosphoglucose/phosphomannose isomerase 521122 pgi 1193404 pgi Aquifex aeolicus VF5 bifunctional phosphoglucose/phosphomannose isomerase NP_213515.1 520160 R 224324 CDS NP_213516.1 15606139 1193405 complement(521156..523126) 1 NC_000918.1 hypothetical protein 523126 1193405 aq_752 Aquifex aeolicus VF5 hypothetical protein NP_213516.1 521156 R 224324 CDS NP_213517.1 15606140 1193406 complement(523123..523422) 1 NC_000918.1 hypothetical protein 523422 1193406 aq_754 Aquifex aeolicus VF5 hypothetical protein NP_213517.1 523123 R 224324 CDS NP_213518.1 15606141 1193407 complement(523415..524143) 1 NC_000918.1 hypothetical protein 524143 1193407 aq_755 Aquifex aeolicus VF5 hypothetical protein NP_213518.1 523415 R 224324 CDS NP_213519.1 15606142 1193408 complement(524140..524829) 1 NC_000918.1 hypothetical protein 524829 1193408 aq_756 Aquifex aeolicus VF5 hypothetical protein NP_213519.1 524140 R 224324 CDS NP_213520.1 15606143 1193409 complement(524822..525361) 1 NC_000918.1 hypothetical protein 525361 1193409 aq_757 Aquifex aeolicus VF5 hypothetical protein NP_213520.1 524822 R 224324 CDS NP_213521.1 15606144 1193410 complement(525358..525855) 1 NC_000918.1 hypothetical protein 525855 1193410 aq_758 Aquifex aeolicus VF5 hypothetical protein NP_213521.1 525358 R 224324 CDS NP_213522.1 15606145 1193411 complement(525855..526304) 1 NC_000918.1 GimC subunit alpha; protein folding pathway ATP-independent; forms a heterohexamer of alpha(2)beta(4); prefoldin subunit alpha 526304 1193411 aq_759 Aquifex aeolicus VF5 prefoldin subunit alpha NP_213522.1 525855 R 224324 CDS NP_213523.1 15606146 1193412 526457..528310 1 NC_000918.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 528310 gidA1 1193412 gidA1 Aquifex aeolicus VF5 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NP_213523.1 526457 D 224324 CDS NP_213524.1 15606147 1193413 528310..529191 1 NC_000918.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 529191 genX 1193413 genX Aquifex aeolicus VF5 lysyl-tRNA synthetase NP_213524.1 528310 D 224324 CDS NP_213525.1 15606148 1193414 complement(529169..529942) 1 NC_000918.1 IclR family transcriptional regulator 529942 iclR 1193414 iclR Aquifex aeolicus VF5 IclR family transcriptional regulator NP_213525.1 529169 R 224324 CDS NP_213526.1 15606149 1193415 529976..531418 1 NC_000918.1 hypothetical protein 531418 1193415 aq_765 Aquifex aeolicus VF5 hypothetical protein NP_213526.1 529976 D 224324 CDS NP_213527.1 15606150 1193416 531396..532250 1 NC_000918.1 hypothetical protein 532250 1193416 aq_766 Aquifex aeolicus VF5 hypothetical protein NP_213527.1 531396 D 224324 CDS NP_213528.1 15606151 1193417 532257..532823 1 NC_000918.1 hypothetical protein 532823 1193417 aq_768 Aquifex aeolicus VF5 hypothetical protein NP_213528.1 532257 D 224324 CDS NP_213529.1 15606152 1193418 532826..533821 1 NC_000918.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 533821 purM 1193418 purM Aquifex aeolicus VF5 phosphoribosylaminoimidazole synthetase NP_213529.1 532826 D 224324 CDS NP_213532.1 15606155 1193421 534837..535613 1 NC_000918.1 hemolysin 535613 tly 1193421 tly Aquifex aeolicus VF5 hemolysin NP_213532.1 534837 D 224324 CDS NP_213533.1 15606156 1193422 535610..536590 1 NC_000918.1 hypothetical protein 536590 1193422 aq_775 Aquifex aeolicus VF5 hypothetical protein NP_213533.1 535610 D 224324 CDS NP_213534.1 15606157 1193423 complement(536587..538119) 1 NC_000918.1 L-aspartate oxidase 538119 nadB 1193423 nadB Aquifex aeolicus VF5 L-aspartate oxidase NP_213534.1 536587 R 224324 CDS NP_213535.1 15606158 1193424 complement(538097..539083) 1 NC_000918.1 hypothetical protein 539083 1193424 aq_778 Aquifex aeolicus VF5 hypothetical protein NP_213535.1 538097 R 224324 CDS NP_213536.1 15606159 1193425 complement(539080..539592) 1 NC_000918.1 hypothetical protein 539592 1193425 aq_780 Aquifex aeolicus VF5 hypothetical protein NP_213536.1 539080 R 224324 CDS NP_213537.1 15606160 1193426 complement(539585..540865) 1 NC_000918.1 histidinol dehydrogenase 540865 hisD 1193426 hisD Aquifex aeolicus VF5 histidinol dehydrogenase NP_213537.1 539585 R 224324 CDS NP_213538.1 15606161 1193427 complement(541304..544306) 1 NC_000918.1 AcrB/AcrD/AcrF family cation efflux protein 544306 acrD4 1193427 acrD4 Aquifex aeolicus VF5 AcrB/AcrD/AcrF family cation efflux protein NP_213538.1 541304 R 224324 CDS NP_213539.1 15606162 1193428 544376..545545 1 NC_000918.1 hypothetical protein 545545 1193428 aq_788 Aquifex aeolicus VF5 hypothetical protein NP_213539.1 544376 D 224324 CDS NP_213540.1 15606163 1193429 545563..546648 1 NC_000918.1 hypothetical protein 546648 1193429 aq_789 Aquifex aeolicus VF5 hypothetical protein NP_213540.1 545563 D 224324 CDS NP_213541.1 15606164 1193430 546645..547136 1 NC_000918.1 hypothetical protein 547136 1193430 aq_791 Aquifex aeolicus VF5 hypothetical protein NP_213541.1 546645 D 224324 CDS NP_213542.1 15606165 1193431 547161..547661 1 NC_000918.1 cytochrome C552 547661 cycB1 1193431 cycB1 Aquifex aeolicus VF5 cytochrome C552 NP_213542.1 547161 D 224324 CDS NP_213543.1 15606166 1193432 547720..547923 1 NC_000918.1 50S ribosomal protein L35 547923 rpmI 1193432 rpmI Aquifex aeolicus VF5 50S ribosomal protein L35 NP_213543.1 547720 D 224324 CDS NP_213544.1 15606167 1193433 complement(547898..549907) 1 NC_000918.1 ATP-dependent DNA helicase REP 549907 rep 1193433 rep Aquifex aeolicus VF5 ATP-dependent DNA helicase REP NP_213544.1 547898 R 224324 CDS NP_213545.1 15606168 1193434 549949..550347 1 NC_000918.1 hypothetical protein 550347 1193434 aq_796 Aquifex aeolicus VF5 hypothetical protein NP_213545.1 549949 D 224324 CDS NP_213546.1 15606169 1193435 550344..551570 1 NC_000918.1 carboxyl-terminal protease 551570 prc 1193435 prc Aquifex aeolicus VF5 carboxyl-terminal protease NP_213546.1 550344 D 224324 CDS NP_213547.1 15606170 1193436 551567..552574 1 NC_000918.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 552574 gcp 1193436 gcp Aquifex aeolicus VF5 DNA-binding/iron metalloprotein/AP endonuclease NP_213547.1 551567 D 224324 CDS NP_213548.1 15606171 1193437 552695..553549 1 NC_000918.1 hydrogenase small subunit 553549 mbhS3 1193437 mbhS3 Aquifex aeolicus VF5 hydrogenase small subunit NP_213548.1 552695 D 224324 CDS NP_213549.1 15606172 1193438 553539..554789 1 NC_000918.1 hydrogenase large subunit 554789 mbhL3 1193438 mbhL3 Aquifex aeolicus VF5 hydrogenase large subunit NP_213549.1 553539 D 224324 CDS NP_213550.1 15606173 1193439 complement(554790..555257) 1 NC_000918.1 hypothetical protein 555257 1193439 aq_805 Aquifex aeolicus VF5 hypothetical protein NP_213550.1 554790 R 224324 CDS NP_213551.1 15606174 1193440 complement(555261..556529) 1 NC_000918.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 556529 pyrC 1193440 pyrC Aquifex aeolicus VF5 dihydroorotase NP_213551.1 555261 R 224324 CDS NP_213552.1 15606175 1193441 complement(556543..557457) 1 NC_000918.1 hypothetical protein 557457 1193441 aq_808 Aquifex aeolicus VF5 hypothetical protein NP_213552.1 556543 R 224324 CDS NP_213553.1 15606176 1193442 complement(557454..558272) 1 NC_000918.1 hypothetical protein 558272 1193442 aq_809 Aquifex aeolicus VF5 hypothetical protein NP_213553.1 557454 R 224324 CDS NP_213554.1 15606177 1193443 complement(558269..558718) 1 NC_000918.1 hypothetical protein 558718 1193443 aq_811 Aquifex aeolicus VF5 hypothetical protein NP_213554.1 558269 R 224324 CDS NP_213555.1 15606178 1193444 558785..559891 1 NC_000918.1 hypothetical protein 559891 1193444 aq_812 Aquifex aeolicus VF5 hypothetical protein NP_213555.1 558785 D 224324 CDS NP_213556.1 15606179 1193445 complement(559888..560256) 1 NC_000918.1 holo-ACP synthase 560256 acpS 1193445 acpS Aquifex aeolicus VF5 holo-ACP synthase NP_213556.1 559888 R 224324 CDS NP_213557.1 15606180 1193446 complement(560253..561119) 1 NC_000918.1 hypothetical protein 561119 1193446 aq_814 Aquifex aeolicus VF5 hypothetical protein NP_213557.1 560253 R 224324 CDS NP_213558.1 15606181 1193447 complement(561119..562285) 1 NC_000918.1 pantothenate metabolism flavoprotein 562285 dfp 1193447 dfp Aquifex aeolicus VF5 pantothenate metabolism flavoprotein NP_213558.1 561119 R 224324 CDS NP_213559.1 15606182 1193448 562310..563584 1 NC_000918.1 glutamate-1-semialdehyde aminotransferase 563584 gsa 1193448 gsa Aquifex aeolicus VF5 glutamate-1-semialdehyde aminotransferase NP_213559.1 562310 D 224324 CDS NP_213560.1 15606183 1193449 563588..564562 1 NC_000918.1 hypothetical protein 564562 1193449 aq_818 Aquifex aeolicus VF5 hypothetical protein NP_213560.1 563588 D 224324 CDS NP_213561.1 15606184 1193450 564520..565839 1 NC_000918.1 apolipoprotein N-acyltransferase 565839 lnt 1193450 lnt Aquifex aeolicus VF5 apolipoprotein N-acyltransferase NP_213561.1 564520 D 224324 CDS NP_213562.1 15606185 1193451 complement(565822..566418) 1 NC_000918.1 hypothetical protein 566418 1193451 aq_820 Aquifex aeolicus VF5 hypothetical protein NP_213562.1 565822 R 224324 CDS NP_213563.1 15606186 1193452 complement(566408..567745) 1 NC_000918.1 UDP-MurNAc-pentapeptide sythetase 567745 murF 1193452 murF Aquifex aeolicus VF5 UDP-MurNAc-pentapeptide sythetase NP_213563.1 566408 R 224324 CDS NP_213564.1 15606187 1193453 573050..573706 1 NC_000918.1 trans-regulatory protein ExsB 573706 exsB 1193453 exsB Aquifex aeolicus VF5 trans-regulatory protein ExsB NP_213564.1 573050 D 224324 CDS NP_213565.1 15606188 1193454 complement(573689..574444) 1 NC_000918.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 574444 surE 1193454 surE Aquifex aeolicus VF5 stationary phase survival protein SurE NP_213565.1 573689 R 224324 CDS NP_213566.1 15606189 1193455 complement(574448..575119) 1 NC_000918.1 flagellar protein FlgA 575119 flgA 1193455 flgA Aquifex aeolicus VF5 flagellar protein FlgA NP_213566.1 574448 R 224324 CDS NP_213567.1 15606190 1193456 complement(575049..575837) 1 NC_000918.1 flagellar hook basal-body protein FlgG 575837 flgG2 1193456 flgG2 Aquifex aeolicus VF5 flagellar hook basal-body protein FlgG NP_213567.1 575049 R 224324 CDS NP_213568.1 15606191 1193457 575881..577305 1 NC_000918.1 NADH oxidase 577305 nox 1193457 nox Aquifex aeolicus VF5 NADH oxidase NP_213568.1 575881 D 224324 CDS NP_213569.1 15606192 1193458 complement(577262..577960) 1 NC_000918.1 hypothetical protein 577960 1193458 aq_836 Aquifex aeolicus VF5 hypothetical protein NP_213569.1 577262 R 224324 CDS NP_213570.1 15606193 1193459 578040..579707 1 NC_000918.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 579707 ilvD 1193459 ilvD Aquifex aeolicus VF5 dihydroxy-acid dehydratase NP_213570.1 578040 D 224324 CDS NP_213571.1 15606194 1193460 complement(579704..580882) 1 NC_000918.1 Dimethylates a single guanine residue of a number of tRNAs using S-adenosyl-L-methionine as a methyl group donor; N(2),N(2)-dimethylguanosine tRNA methyltransferase 580882 trm1 1193460 trm1 Aquifex aeolicus VF5 N(2),N(2)-dimethylguanosine tRNA methyltransferase NP_213571.1 579704 R 224324 CDS NP_213572.1 15606195 1193461 580901..581302 1 NC_000918.1 hypothetical protein 581302 1193461 aq_843 Aquifex aeolicus VF5 hypothetical protein NP_213572.1 580901 D 224324 CDS NP_213573.1 15606196 1193554 complement(581303..583393) 1 NC_000918.1 (p)ppGpp 3-pyrophosphohydrolase 583393 spoT 1193554 spoT Aquifex aeolicus VF5 (p)ppGpp 3-pyrophosphohydrolase NP_213573.1 581303 R 224324 CDS NP_213574.1 15606197 1193555 583431..584456 1 NC_000918.1 rod shape-determining protein MreB 584456 mreB 1193555 mreB Aquifex aeolicus VF5 rod shape-determining protein MreB NP_213574.1 583431 D 224324 CDS NP_213575.1 15606198 1193556 584453..585247 1 NC_000918.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 585247 1193556 aq_847 Aquifex aeolicus VF5 rod shape-determining protein MreC NP_213575.1 584453 D 224324 CDS NP_213576.1 15606199 1193557 585510..585842 1 NC_000918.1 hypothetical protein 585842 1193557 aq_848 Aquifex aeolicus VF5 hypothetical protein NP_213576.1 585510 D 224324 CDS NP_213577.1 15606200 1193558 complement(586081..587379) 1 NC_000918.1 hypothetical protein 587379 1193558 aq_849 Aquifex aeolicus VF5 hypothetical protein NP_213577.1 586081 R 224324 CDS NP_213578.1 15606201 1193559 complement(587390..587806) 1 NC_000918.1 hypothetical protein 587806 1193559 aq_850 Aquifex aeolicus VF5 hypothetical protein NP_213578.1 587390 R 224324 CDS NP_213579.1 15606202 1193560 complement(587797..588756) 1 NC_000918.1 Mg(2+) and Co(2+) transport protein 588756 corA 1193560 corA Aquifex aeolicus VF5 Mg(2+) and Co(2+) transport protein NP_213579.1 587797 R 224324 CDS NP_213580.1 15606203 1193561 complement(588743..589705) 1 NC_000918.1 pyridoxal phosphate biosynthetic protein PdxA 589705 pdxA 1193561 pdxA Aquifex aeolicus VF5 pyridoxal phosphate biosynthetic protein PdxA NP_213580.1 588743 R 224324 CDS NP_213581.1 15606204 1193562 complement(589698..590042) 1 NC_000918.1 hypothetical protein 590042 1193562 aq_853 Aquifex aeolicus VF5 hypothetical protein NP_213581.1 589698 R 224324 CDS NP_213582.1 15606205 1193563 complement(590053..591690) 1 NC_000918.1 hypothetical protein 591690 1193563 aq_854 Aquifex aeolicus VF5 hypothetical protein NP_213582.1 590053 R 224324 CDS NP_213583.1 15606206 1193564 complement(591687..592580) 1 NC_000918.1 hypothetical protein 592580 1193564 aq_855 Aquifex aeolicus VF5 hypothetical protein NP_213583.1 591687 R 224324 CDS NP_213584.1 15606207 1193565 592596..593246 1 NC_000918.1 phosphoribosylglycinamide formyltransferase 593246 purN 1193565 purN Aquifex aeolicus VF5 phosphoribosylglycinamide formyltransferase NP_213584.1 592596 D 224324 CDS NP_213585.1 15606208 1193566 complement(593526..594194) 1 NC_000918.1 alkyl hydroperoxide reductase 594194 ahpC2 1193566 ahpC2 Aquifex aeolicus VF5 alkyl hydroperoxide reductase NP_213585.1 593526 R 224324 CDS NP_213586.1 15606209 1193567 complement(594616..594945) 1 NC_000918.1 hypothetical protein 594945 1193567 aq_862 Aquifex aeolicus VF5 hypothetical protein NP_213586.1 594616 R 224324 CDS NP_213587.1 15606210 1193568 complement(594938..597961) 1 NC_000918.1 hypothetical protein 597961 1193568 aq_863 Aquifex aeolicus VF5 hypothetical protein NP_213587.1 594938 R 224324 CDS NP_213588.1 15606211 1193569 complement(597975..600338) 1 NC_000918.1 NADH dehydrogenase I subunit L 600338 nuoL2 1193569 nuoL2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit L NP_213588.1 597975 R 224324 CDS NP_213589.1 15606212 1193570 complement(600393..600596) 1 NC_000918.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 600596 rpsU 1193570 rpsU Aquifex aeolicus VF5 30S ribosomal protein S21 NP_213589.1 600393 R 224324 CDS NP_213590.1 15606213 1193571 complement(600882..601706) 1 NC_000918.1 quinolinate phosphoribosyl transferase 601706 nadC 1193571 nadC Aquifex aeolicus VF5 quinolinate phosphoribosyl transferase NP_213590.1 600882 R 224324 CDS NP_213591.1 15606214 1193572 601852..603198 1 NC_000918.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 603198 trmE 1193572 trmE Aquifex aeolicus VF5 tRNA modification GTPase TrmE NP_213591.1 601852 D 224324 CDS NP_213592.1 15606215 1193573 603214..604524 1 NC_000918.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 604524 rho 1193573 rho Aquifex aeolicus VF5 transcription termination factor Rho NP_213592.1 603214 D 224324 CDS NP_213593.1 15607141 1194009 604575..604781 1 NC_000918.1 50S ribosomal protein L31 604781 rpmE 1194009 rpmE Aquifex aeolicus VF5 50S ribosomal protein L31 NP_213593.1 604575 D 224324 CDS NP_213594.1 15606216 1193574 604785..605873 1 NC_000918.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 605873 prfA 1193574 prfA Aquifex aeolicus VF5 peptide chain release factor 1 NP_213594.1 604785 D 224324 CDS NP_213595.1 15606217 1193575 complement(606111..606899) 1 NC_000918.1 septum site-determining protein MinD 606899 minD2 1193575 minD2 Aquifex aeolicus VF5 septum site-determining protein MinD NP_213595.1 606111 R 224324 CDS NP_213596.1 15606218 1193576 complement(606878..607483) 1 NC_000918.1 septum site-determining protein MinC 607483 minC 1193576 minC Aquifex aeolicus VF5 septum site-determining protein MinC NP_213596.1 606878 R 224324 CDS NP_213597.1 15606219 1193577 607507..608085 1 NC_000918.1 hypothetical protein 608085 1193577 aq_880 Aquifex aeolicus VF5 hypothetical protein NP_213597.1 607507 D 224324 CDS NP_213598.1 15606220 1193578 complement(608082..609968) 1 NC_000918.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 609968 1193578 aq_881 Aquifex aeolicus VF5 1-deoxy-D-xylulose-5-phosphate synthase NP_213598.1 608082 R 224324 CDS NP_213599.1 15606221 1193579 complement(610406..613846) 1 NC_000918.1 catalyzes the magnesium and ATP-dependent positive supercoiling of DNA; contains helicase and topoisomerase domains; reverse gyrase 613846 topG2 1193579 topG2 Aquifex aeolicus VF5 reverse gyrase NP_213599.1 610406 R 224324 CDS NP_213600.1 15606222 1193580 613977..614423 1 NC_000918.1 hypothetical protein 614423 1193580 aq_888 Aquifex aeolicus VF5 hypothetical protein NP_213600.1 613977 D 224324 CDS NP_213601.1 15606223 1193581 614467..615270 1 NC_000918.1 hypothetical protein 615270 1193581 aq_890 Aquifex aeolicus VF5 hypothetical protein NP_213601.1 614467 D 224324 CDS NP_213602.1 15606224 1193582 complement(615250..616188) 1 NC_000918.1 exopolyphosphatase 616188 ppx 1193582 ppx Aquifex aeolicus VF5 exopolyphosphatase NP_213602.1 615250 R 224324 CDS NP_213603.1 15606225 1193583 616148..617128 1 NC_000918.1 malonyl-CoA:ACP transacylase 617128 fabD 1193583 fabD Aquifex aeolicus VF5 malonyl-CoA:ACP transacylase NP_213603.1 616148 D 224324 CDS NP_213604.1 15606226 1193584 617125..617976 1 NC_000918.1 hypothetical protein 617976 1193584 aq_893 Aquifex aeolicus VF5 hypothetical protein NP_213604.1 617125 D 224324 CDS NP_213605.1 15606227 1193585 complement(617965..618969) 1 NC_000918.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 618969 queA 1193585 queA Aquifex aeolicus VF5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase NP_213605.1 617965 R 224324 CDS NP_213606.1 15606228 1193586 complement(618982..619896) 1 NC_000918.1 octoprenyl-diphosphate synthase 619896 ispB 1193586 ispB Aquifex aeolicus VF5 octoprenyl-diphosphate synthase NP_213606.1 618982 R 224324 CDS NP_213607.1 15606229 1193587 620083..620556 1 NC_000918.1 NifU protein 620556 nifU 1193587 nifU Aquifex aeolicus VF5 NifU protein NP_213607.1 620083 D 224324 CDS NP_213611.1 15606233 1193591 622364..623173 1 NC_000918.1 shikimate 5-dehydrogenase 623173 aroE 1193591 aroE Aquifex aeolicus VF5 shikimate 5-dehydrogenase NP_213611.1 622364 D 224324 CDS NP_213612.1 15606234 1193592 623166..623621 1 NC_000918.1 hypothetical protein 623621 1193592 aq_903 Aquifex aeolicus VF5 hypothetical protein NP_213612.1 623166 D 224324 CDS NP_213613.1 15606235 1193593 623622..624131 1 NC_000918.1 hypothetical protein 624131 1193593 aq_904 Aquifex aeolicus VF5 hypothetical protein NP_213613.1 623622 D 224324 CDS NP_213614.1 15606236 1193594 complement(624284..625825) 1 NC_000918.1 histidine kinase sensor protein 625825 hksP3 1193594 hksP3 Aquifex aeolicus VF5 histidine kinase sensor protein NP_213614.1 624284 R 224324 CDS NP_213615.1 15606237 1193595 complement(625818..626483) 1 NC_000918.1 PhoU family transcriptional regulator 626483 phoU 1193595 phoU Aquifex aeolicus VF5 PhoU family transcriptional regulator NP_213615.1 625818 R 224324 CDS NP_213616.1 15606238 1193596 626498..627073 1 NC_000918.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 627073 gmhA 1193596 gmhA Aquifex aeolicus VF5 phosphoheptose isomerase NP_213616.1 626498 D 224324 CDS NP_213617.1 15606239 1193597 627058..627882 1 NC_000918.1 hypothetical protein 627882 1193597 aq_909 Aquifex aeolicus VF5 hypothetical protein NP_213617.1 627058 D 224324 CDS NP_213618.1 15606240 1193598 complement(627868..628575) 1 NC_000918.1 DNA replication protein DnaC 628575 dnaC 1193598 dnaC Aquifex aeolicus VF5 DNA replication protein DnaC NP_213618.1 627868 R 224324 CDS NP_213619.1 15606241 1193599 complement(628608..629369) 1 NC_000918.1 erythrocyte band 7-like protein 629369 ebs 1193599 ebs Aquifex aeolicus VF5 erythrocyte band 7-like protein NP_213619.1 628608 R 224324 CDS NP_213620.1 15606242 1193600 complement(629378..630031) 1 NC_000918.1 hypothetical protein 630031 1193600 aq_913 Aquifex aeolicus VF5 hypothetical protein NP_213620.1 629378 R 224324 CDS NP_213621.1 15606243 1193601 630065..630421 1 NC_000918.1 hypothetical protein 630421 1193601 aq_914 Aquifex aeolicus VF5 hypothetical protein NP_213621.1 630065 D 224324 CDS NP_213622.1 15606244 1193602 630432..631238 1 NC_000918.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 631238 1193602 aq_915 Aquifex aeolicus VF5 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_213622.1 630432 D 224324 CDS NP_213623.1 15606245 1193603 631526..632323 1 NC_000918.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 632323 dapB 1193603 dapB Aquifex aeolicus VF5 dihydrodipicolinate reductase NP_213623.1 631526 D 224324 CDS NP_213624.1 15606246 1193604 complement(632293..633519) 1 NC_000918.1 hypothetical protein 633519 1193604 aq_917 Aquifex aeolicus VF5 hypothetical protein NP_213624.1 632293 R 224324 CDS NP_213625.1 15606247 1193605 complement(633516..633977) 1 NC_000918.1 hypothetical protein 633977 1193605 aq_918 Aquifex aeolicus VF5 hypothetical protein NP_213625.1 633516 R 224324 CDS NP_213626.1 15606248 1193606 633962..634441 1 NC_000918.1 hypothetical protein 634441 1193606 aq_919 Aquifex aeolicus VF5 hypothetical protein NP_213626.1 633962 D 224324 CDS NP_213627.1 15606249 1193607 complement(634438..634728) 1 NC_000918.1 ferredoxin 634728 fdx1 1193607 fdx1 Aquifex aeolicus VF5 ferredoxin NP_213627.1 634438 R 224324 CDS NP_213628.1 15606250 1193608 complement(634779..636164) 1 NC_000918.1 cell division protein FtsY 636164 ftsY 1193608 ftsY Aquifex aeolicus VF5 cell division protein FtsY NP_213628.1 634779 R 224324 CDS NP_213629.1 15606251 1193609 complement(636198..637814) 1 NC_000918.1 hypothetical protein 637814 1193609 aq_922 Aquifex aeolicus VF5 hypothetical protein NP_213629.1 636198 R 224324 CDS NP_213630.1 15606252 1193610 637841..639592 1 NC_000918.1 arginyl-tRNA synthetase 639592 argS 1193610 argS Aquifex aeolicus VF5 arginyl-tRNA synthetase NP_213630.1 637841 D 224324 CDS NP_213631.1 15606253 1193611 639612..640379 1 NC_000918.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 640379 rph 1193611 rph Aquifex aeolicus VF5 ribonuclease PH NP_213631.1 639612 D 224324 CDS NP_213632.1 15606254 1193612 640337..641095 1 NC_000918.1 hypothetical protein 641095 1193612 aq_926 Aquifex aeolicus VF5 hypothetical protein NP_213632.1 640337 D 224324 CDS NP_213633.1 15606255 1193613 641141..641731 1 NC_000918.1 hypothetical protein 641731 1193613 aq_928 Aquifex aeolicus VF5 hypothetical protein NP_213633.1 641141 D 224324 CDS NP_213634.1 15606256 1193614 641743..642969 1 NC_000918.1 Na(+)/H(+) antiporter 642969 napA2 1193614 napA2 Aquifex aeolicus VF5 Na(+)/H(+) antiporter NP_213634.1 641743 D 224324 CDS NP_213635.1 15606257 1193615 643202..643591 1 NC_000918.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 643591 1193615 aq_931 Aquifex aeolicus VF5 7-cyano-7-deazaguanine reductase NP_213635.1 643202 D 224324 CDS NP_213636.1 15606258 1193616 complement(643713..644321) 1 NC_000918.1 DNA polymerase III subunit epsilon 644321 dnaQ 1193616 dnaQ Aquifex aeolicus VF5 DNA polymerase III subunit epsilon NP_213636.1 643713 R 224324 CDS NP_213637.1 15607138 1194006 complement(644296..644529) 1 NC_000918.1 phosphoribosylformylglycinamidine (FGAM) synthase subunit PurS 644529 purS 1194006 purS Aquifex aeolicus VF5 phosphoribosylformylglycinamidine (FGAM) synthase subunit PurS NP_213637.1 644296 R 224324 CDS NP_213638.1 15606259 1193617 complement(644552..645313) 1 NC_000918.1 hypothetical protein 645313 1193617 aq_933 Aquifex aeolicus VF5 hypothetical protein NP_213638.1 644552 R 224324 CDS NP_213639.1 15606260 1193618 complement(645310..645783) 1 NC_000918.1 hypothetical protein 645783 1193618 aq_935 Aquifex aeolicus VF5 hypothetical protein NP_213639.1 645310 R 224324 CDS NP_213640.1 15606261 1193619 645833..647737 1 NC_000918.1 cell division protein FtsH 647737 ftsH 1193619 ftsH Aquifex aeolicus VF5 cell division protein FtsH NP_213640.1 645833 D 224324 CDS NP_213641.1 15606262 1193620 647737..649035 1 NC_000918.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; 3-isopropylmalate dehydratase large subunit 649035 leuC 1193620 leuC Aquifex aeolicus VF5 3-isopropylmalate dehydratase large subunit NP_213641.1 647737 D 224324 CDS NP_213642.1 15606263 1193621 650221..650544 1 NC_000918.1 hypothetical protein 650544 1193621 aq_943 Aquifex aeolicus VF5 hypothetical protein NP_213642.1 650221 D 224324 CDS NP_213643.1 15606264 1193622 650617..651102 1 NC_000918.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 651102 gcsH3 1193622 gcsH3 Aquifex aeolicus VF5 glycine cleavage system protein H NP_213643.1 650617 D 224324 CDS NP_213644.1 15606265 1193623 651393..652250 1 NC_000918.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 652250 glyQ 1193623 glyQ Aquifex aeolicus VF5 glycyl-tRNA synthetase subunit alpha NP_213644.1 651393 D 224324 CDS NP_213645.1 15606266 1193624 652228..652893 1 NC_000918.1 RNase III 652893 rnc 1193624 rnc Aquifex aeolicus VF5 RNase III NP_213645.1 652228 D 224324 CDS NP_213646.1 15606267 1193625 652890..653819 1 NC_000918.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 653819 hemH 1193625 hemH Aquifex aeolicus VF5 ferrochelatase NP_213646.1 652890 D 224324 CDS NP_213647.1 15606268 1193626 654176..654538 1 NC_000918.1 hypothetical protein 654538 1193626 aq_950 Aquifex aeolicus VF5 hypothetical protein NP_213647.1 654176 D 224324 CDS NP_213648.1 15606269 1193627 complement(654542..655630) 1 NC_000918.1 chorismate mutase/prephenate dehydratase 655630 pheA 1193627 pheA Aquifex aeolicus VF5 chorismate mutase/prephenate dehydratase NP_213648.1 654542 R 224324 CDS NP_213649.1 15606270 1193628 655685..656041 1 NC_000918.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 656041 rplT 1193628 rplT Aquifex aeolicus VF5 50S ribosomal protein L20 NP_213649.1 655685 D 224324 CDS NP_213650.1 15606271 1193629 656041..657057 1 NC_000918.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 657057 pheS 1193629 pheS Aquifex aeolicus VF5 phenylalanyl-tRNA synthetase subunit alpha NP_213650.1 656041 D 224324 CDS NP_213651.1 15606272 1193630 657066..657836 1 NC_000918.1 type-I signal peptidase 657836 lepB 1193630 lepB Aquifex aeolicus VF5 type-I signal peptidase NP_213651.1 657066 D 224324 CDS NP_213652.1 15606273 1193631 657836..658306 1 NC_000918.1 hypothetical protein 658306 1193631 aq_957 Aquifex aeolicus VF5 hypothetical protein NP_213652.1 657836 D 224324 CDS NP_213653.1 15606274 1193632 658313..659230 1 NC_000918.1 phosphotidylglycerophosphate synthase 659230 pgsA2 1193632 pgsA2 Aquifex aeolicus VF5 phosphotidylglycerophosphate synthase NP_213653.1 658313 D 224324 CDS NP_213654.1 15606275 1193633 complement(658796..660499) 1 NC_000918.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 660499 nadE 1193633 nadE Aquifex aeolicus VF5 NAD synthetase NP_213654.1 658796 R 224324 CDS NP_213655.1 15606276 1193634 complement(660510..662204) 1 NC_000918.1 hydrogenase large subunit 662204 mbhL2 1193634 mbhL2 Aquifex aeolicus VF5 hydrogenase large subunit NP_213655.1 660510 R 224324 CDS NP_213656.1 15606277 1193635 complement(662201..663505) 1 NC_000918.1 heterodisulfide reductase 663505 hdrD 1193635 hdrD Aquifex aeolicus VF5 heterodisulfide reductase NP_213656.1 662201 R 224324 CDS NP_213657.1 15606278 1193636 complement(663518..664198) 1 NC_000918.1 hypothetical protein 664198 1193636 aq_963 Aquifex aeolicus VF5 hypothetical protein NP_213657.1 663518 R 224324 CDS NP_213658.1 15606279 1193637 complement(664198..665247) 1 NC_000918.1 hydrogenase small subunit 665247 mbhS2 1193637 mbhS2 Aquifex aeolicus VF5 hydrogenase small subunit NP_213658.1 664198 R 224324 CDS NP_213660.1 15606281 1193639 666538..668499 1 NC_000918.1 organic solvent tolerance protein 668499 ostA 1193639 ostA Aquifex aeolicus VF5 organic solvent tolerance protein NP_213660.1 666538 D 224324 CDS NP_213661.1 15606282 1193640 complement(668496..669164) 1 NC_000918.1 ribulose-5-phosphate 3-epimerase 669164 cbbE2 1193640 cbbE2 Aquifex aeolicus VF5 ribulose-5-phosphate 3-epimerase NP_213661.1 668496 R 224324 CDS NP_213662.1 15606283 1193641 669174..669761 1 NC_000918.1 thymidylate kinase 669761 tmk 1193641 tmk Aquifex aeolicus VF5 thymidylate kinase NP_213662.1 669174 D 224324 CDS NP_213663.1 15606284 1193642 complement(669738..670877) 1 NC_000918.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 670877 argJ 1193642 argJ Aquifex aeolicus VF5 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase NP_213663.1 669738 R 224324 CDS NP_213664.1 15606285 1193643 complement(670887..672164) 1 NC_000918.1 hypothetical protein 672164 1193643 aq_972 Aquifex aeolicus VF5 hypothetical protein NP_213664.1 670887 R 224324 CDS NP_213665.1 15606286 1193644 672190..673695 1 NC_000918.1 protein export membrane protein SecD 673695 secD 1193644 secD Aquifex aeolicus VF5 protein export membrane protein SecD NP_213665.1 672190 D 224324 CDS NP_213666.1 15606287 1193645 673738..674661 1 NC_000918.1 beta lactamase 674661 cphA2 1193645 cphA2 Aquifex aeolicus VF5 beta lactamase NP_213666.1 673738 D 224324 CDS NP_213667.1 15606288 1193738 674673..675671 1 NC_000918.1 biotin synthetase 675671 bioB 1193738 bioB Aquifex aeolicus VF5 biotin synthetase NP_213667.1 674673 D 224324 CDS NP_213668.1 15606289 1193739 675750..676754 1 NC_000918.1 hypothetical protein 676754 1193739 aq_977 Aquifex aeolicus VF5 hypothetical protein NP_213668.1 675750 D 224324 CDS NP_213669.1 15606290 1193740 676751..677188 1 NC_000918.1 hypothetical protein 677188 1193740 aq_978 Aquifex aeolicus VF5 hypothetical protein NP_213669.1 676751 D 224324 CDS NP_213670.1 15606291 1193741 complement(677185..677787) 1 NC_000918.1 hypothetical protein 677787 1193741 aq_979 Aquifex aeolicus VF5 hypothetical protein NP_213670.1 677185 R 224324 CDS NP_213671.1 15606292 1193742 677905..680139 1 NC_000918.1 DNA gyrase A subunit 680139 gyrA 1193742 gyrA Aquifex aeolicus VF5 DNA gyrase A subunit NP_213671.1 677905 D 224324 CDS NP_213672.1 15606293 1193743 680212..681090 1 NC_000918.1 hypothetical protein 681090 1193743 aq_983 Aquifex aeolicus VF5 hypothetical protein NP_213672.1 680212 D 224324 CDS NP_213673.1 15606294 1193744 complement(681087..682298) 1 NC_000918.1 hypothetical protein 682298 1193744 aq_985 Aquifex aeolicus VF5 hypothetical protein NP_213673.1 681087 R 224324 CDS NP_213674.1 15606295 1193745 complement(682302..682805) 1 NC_000918.1 hypothetical protein 682805 1193745 aq_986 Aquifex aeolicus VF5 hypothetical protein NP_213674.1 682302 R 224324 CDS NP_213675.1 15606296 1193746 complement(682778..683275) 1 NC_000918.1 hypothetical protein 683275 1193746 aq_987 Aquifex aeolicus VF5 hypothetical protein NP_213675.1 682778 R 224324 CDS NP_213676.1 15606297 1193747 complement(683288..683881) 1 NC_000918.1 hypothetical protein 683881 1193747 aq_988 Aquifex aeolicus VF5 hypothetical protein NP_213676.1 683288 R 224324 CDS NP_213677.1 15606298 1193748 complement(683881..684636) 1 NC_000918.1 hypothetical protein 684636 1193748 aq_990 Aquifex aeolicus VF5 hypothetical protein NP_213677.1 683881 R 224324 CDS NP_213678.1 15606299 1193749 684685..685872 1 NC_000918.1 catalyzes a two-step reaction; first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 685872 trpS 1193749 trpS Aquifex aeolicus VF5 tryptophanyl-tRNA synthetase NP_213678.1 684685 D 224324 CDS NP_213679.1 15606300 1193750 685872..686903 1 NC_000918.1 hypothetical protein 686903 1193750 aq_993 Aquifex aeolicus VF5 hypothetical protein NP_213679.1 685872 D 224324 CDS NP_213680.1 15606301 1193751 686941..687537 1 NC_000918.1 pyrazinamidase/nicotinamidase 687537 pncA 1193751 pncA Aquifex aeolicus VF5 pyrazinamidase/nicotinamidase NP_213680.1 686941 D 224324 CDS NP_213681.1 15606302 1193752 687606..689504 1 NC_000918.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 689504 dnaK 1193752 dnaK Aquifex aeolicus VF5 molecular chaperone DnaK NP_213681.1 687606 D 224324 CDS NP_213682.1 15606303 1193753 complement(689521..691992) 1 NC_000918.1 long-chain-fatty-acid CoA ligase 691992 fadD 1193753 fadD Aquifex aeolicus VF5 long-chain-fatty-acid CoA ligase NP_213682.1 689521 R 224324 CDS NP_213683.1 15606304 1193754 complement(692496..693170) 1 NC_000918.1 flagellar motor protein MotB-like 693170 motB2 1193754 motB2 Aquifex aeolicus VF5 flagellar motor protein MotB-like NP_213683.1 692496 R 224324 CDS NP_213684.1 15606305 1193755 complement(693181..693888) 1 NC_000918.1 flagellar motor protein MotB 693888 motB1 1193755 motB1 Aquifex aeolicus VF5 flagellar motor protein MotB NP_213684.1 693181 R 224324 CDS NP_213685.1 15606306 1193756 complement(693892..694656) 1 NC_000918.1 flagellar motor protein MotA 694656 motA 1193756 motA Aquifex aeolicus VF5 flagellar motor protein MotA NP_213685.1 693892 R 224324 CDS NP_213686.1 15606307 1193757 694699..695013 1 NC_000918.1 periplasmic divalent cation tolerance protein 695013 cutA 1193757 cutA Aquifex aeolicus VF5 periplasmic divalent cation tolerance protein NP_213686.1 694699 D 224324 CDS NP_213687.1 15606308 1193758 695010..697946 1 NC_000918.1 hypothetical protein 697946 1193758 aq_1006 Aquifex aeolicus VF5 hypothetical protein NP_213687.1 695010 D 224324 CDS NP_213688.1 15606309 1193759 complement(697943..701428) 1 NC_000918.1 DNA polymerase III subunit alpha 701428 dnaE 1193759 dnaE Aquifex aeolicus VF5 DNA polymerase III subunit alpha NP_213688.1 697943 R 224324 CDS NP_213689.1 15606310 1193760 complement(701440..702204) 1 NC_000918.1 dehydrogenase 702204 udh 1193760 udh Aquifex aeolicus VF5 dehydrogenase NP_213689.1 701440 R 224324 CDS NP_213690.1 15606311 1193761 702179..702643 1 NC_000918.1 hypothetical protein 702643 1193761 aq_1012 Aquifex aeolicus VF5 hypothetical protein NP_213690.1 702179 D 224324 CDS NP_213691.1 15606312 1193762 702655..703965 1 NC_000918.1 hypothetical protein 703965 1193762 aq_1013 Aquifex aeolicus VF5 hypothetical protein NP_213691.1 702655 D 224324 CDS NP_213692.1 15606313 1193763 complement(703949..705178) 1 NC_000918.1 collagenase 705178 col 1193763 col Aquifex aeolicus VF5 collagenase NP_213692.1 703949 R 224324 CDS NP_213693.1 15606314 1193764 705255..705662 1 NC_000918.1 hypothetical protein 705662 1193764 aq_1017 Aquifex aeolicus VF5 hypothetical protein NP_213693.1 705255 D 224324 CDS NP_213694.1 15606315 1193765 705653..706033 1 NC_000918.1 hypothetical protein 706033 1193765 aq_1018 Aquifex aeolicus VF5 hypothetical protein NP_213694.1 705653 D 224324 CDS NP_213695.1 15606316 1193766 706456..707454 1 NC_000918.1 hydrogenase expression/formation protein 707454 hypE 1193766 hypE Aquifex aeolicus VF5 hydrogenase expression/formation protein NP_213695.1 706456 D 224324 CDS NP_213696.1 15606317 1193767 707454..707801 1 NC_000918.1 hydrogenase accessory protein HypA 707801 hypA 1193767 hypA Aquifex aeolicus VF5 hydrogenase accessory protein HypA NP_213696.1 707454 D 224324 CDS NP_213697.1 15606318 1193768 707801..708835 1 NC_000918.1 hypothetical protein 708835 1193768 aq_1022 Aquifex aeolicus VF5 hypothetical protein NP_213697.1 707801 D 224324 CDS NP_213698.1 15606319 1193769 complement(708832..709959) 1 NC_000918.1 acetoin utilization protein 709959 acuC1 1193769 acuC1 Aquifex aeolicus VF5 acetoin utilization protein NP_213698.1 708832 R 224324 CDS NP_213699.1 15606320 1193770 complement(709946..710791) 1 NC_000918.1 hypothetical protein 710791 1193770 aq_1024 Aquifex aeolicus VF5 hypothetical protein NP_213699.1 709946 R 224324 CDS NP_213700.1 15606321 1193771 complement(710781..713159) 1 NC_000918.1 gyrase B 713159 gyrB 1193771 gyrB Aquifex aeolicus VF5 gyrase B NP_213700.1 710781 R 224324 CDS NP_213701.1 15606322 1193772 complement(713175..713570) 1 NC_000918.1 hypothetical protein 713570 1193772 aq_1029 Aquifex aeolicus VF5 hypothetical protein NP_213701.1 713175 R 224324 CDS NP_213702.1 15606323 1193773 complement(713839..714774) 1 NC_000918.1 selenophosphate synthase 714774 selD 1193773 selD Aquifex aeolicus VF5 selenophosphate synthase NP_213702.1 713839 R 224324 CDS NP_213703.1 15606324 1193774 complement(714928..716286) 1 NC_000918.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 716286 selA 1193774 selA Aquifex aeolicus VF5 selenocysteine synthase NP_213703.1 714928 R 224324 CDS NP_213704.1 15606325 1193775 716314..718062 1 NC_000918.1 elongation factor SelB 718062 selB 1193775 selB Aquifex aeolicus VF5 elongation factor SelB NP_213704.1 716314 D 224324 CDS NP_213707.1 15606328 1193778 complement(719238..719681) 1 NC_000918.1 hypothetical protein 719681 1193778 aq_1037 Aquifex aeolicus VF5 hypothetical protein NP_213707.1 719238 R 224324 CDS NP_213708.1 15606329 1193779 719732..720652 1 NC_000918.1 LysR family transcriptional regulator 720652 lysR2 1193779 lysR2 Aquifex aeolicus VF5 LysR family transcriptional regulator NP_213708.1 719732 D 224324 CDS NP_213709.1 15606330 1193780 720865..723912 1 NC_000918.1 formate dehydrogenase subunit alpha 723912 fdoG 1193780 fdoG Aquifex aeolicus VF5 formate dehydrogenase subunit alpha NP_213709.1 720865 D 224324 CDS NP_213710.1 15606331 1193781 723927..724838 1 NC_000918.1 formate dehydrogenase subunit beta 724838 fdoH 1193781 fdoH Aquifex aeolicus VF5 formate dehydrogenase subunit beta NP_213710.1 723927 D 224324 CDS NP_213711.1 15606332 1193782 724841..725476 1 NC_000918.1 formate dehydrogenase subunit gamma 725476 fdoI 1193782 fdoI Aquifex aeolicus VF5 formate dehydrogenase subunit gamma NP_213711.1 724841 D 224324 CDS NP_213712.1 15606333 1193783 725496..726005 1 NC_000918.1 superoxide dismutase (Cu/Zn) 726005 sodC1 1193783 sodC1 Aquifex aeolicus VF5 superoxide dismutase (Cu/Zn) NP_213712.1 725496 D 224324 CDS NP_213713.1 15606334 1193784 725987..726838 1 NC_000918.1 formate dehydrogenase formation protein FdhE 726838 fdhE 1193784 fdhE Aquifex aeolicus VF5 formate dehydrogenase formation protein FdhE NP_213713.1 725987 D 224324 CDS NP_213714.1 15606335 1193785 726937..727368 1 NC_000918.1 glycine cleavage system protein H 727368 gcsH1 1193785 gcsH1 Aquifex aeolicus VF5 glycine cleavage system protein H NP_213714.1 726937 D 224324 CDS NP_213715.1 15606336 1193786 727480..728592 1 NC_000918.1 FeS cluster formation protein NifS 728592 nifS1 1193786 nifS1 Aquifex aeolicus VF5 FeS cluster formation protein NifS NP_213715.1 727480 D 224324 CDS NP_213716.1 15606337 1193787 728999..729784 1 NC_000918.1 hypothetical protein 729784 1193787 aq_1054 Aquifex aeolicus VF5 hypothetical protein NP_213716.1 728999 D 224324 CDS NP_213717.1 15606338 1193788 complement(729781..730554) 1 NC_000918.1 phosphate transport ATP binding protein 730554 pstB 1193788 pstB Aquifex aeolicus VF5 phosphate transport ATP binding protein NP_213717.1 729781 R 224324 CDS NP_213718.1 15606339 1193789 730704..731984 1 NC_000918.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 731984 1193789 aq_1056 Aquifex aeolicus VF5 nicotinate phosphoribosyltransferase NP_213718.1 730704 D 224324 CDS NP_213719.1 15606340 1193790 complement(731970..732470) 1 NC_000918.1 hypothetical protein 732470 1193790 aq_1057 Aquifex aeolicus VF5 hypothetical protein NP_213719.1 731970 R 224324 CDS NP_213720.1 15606341 1193791 732523..733062 1 NC_000918.1 TetR/AcrR family transcriptional regulator 733062 acrR1 1193791 acrR1 Aquifex aeolicus VF5 TetR/AcrR family transcriptional regulator NP_213720.1 732523 D 224324 CDS NP_213721.1 15606342 1193792 733053..734306 1 NC_000918.1 hypothetical protein 734306 1193792 aq_1059 Aquifex aeolicus VF5 hypothetical protein NP_213721.1 733053 D 224324 CDS NP_213722.1 15606343 1193793 734303..735427 1 NC_000918.1 hypothetical protein 735427 1193793 aq_1060 Aquifex aeolicus VF5 hypothetical protein NP_213722.1 734303 D 224324 CDS NP_213723.1 15606344 1193794 735424..736959 1 NC_000918.1 major facilitator family transporter 736959 emrB 1193794 emrB Aquifex aeolicus VF5 major facilitator family transporter NP_213723.1 735424 D 224324 CDS NP_213724.1 15606345 1193795 complement(736956..737984) 1 NC_000918.1 glyceraldehyde-3-phosphate dehydrogenase 737984 gap 1193795 gap Aquifex aeolicus VF5 glyceraldehyde-3-phosphate dehydrogenase NP_213724.1 736956 R 224324 CDS NP_213725.1 15606346 1193796 738025..738942 1 NC_000918.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 738942 miaA 1193796 miaA Aquifex aeolicus VF5 tRNA delta(2)-isopentenylpyrophosphate transferase NP_213725.1 738025 D 224324 CDS YP_008920731.1 566344051 17925350 739492..739749 1 NC_000918.1 nitrogen-fixing protein NifU 739749 17925350 aq_1067a Aquifex aeolicus VF5 nitrogen-fixing protein NifU YP_008920731.1 739492 D 224324 CDS NP_213726.1 15606347 1193797 complement(739746..741233) 1 NC_000918.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 741233 cysS 1193797 cysS Aquifex aeolicus VF5 cysteinyl-tRNA synthetase NP_213726.1 739746 R 224324 CDS NP_213727.1 15606348 1193798 complement(741238..742221) 1 NC_000918.1 UDP-glucose-4-epimerase 742221 galE 1193798 galE Aquifex aeolicus VF5 UDP-glucose-4-epimerase NP_213727.1 741238 R 224324 CDS NP_213728.1 15606349 1193799 742238..742948 1 NC_000918.1 hypothetical protein 742948 1193799 aq_1070 Aquifex aeolicus VF5 hypothetical protein NP_213728.1 742238 D 224324 CDS NP_213729.1 15606350 1193800 742979..744310 1 NC_000918.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 744310 proA 1193800 proA Aquifex aeolicus VF5 gamma-glutamyl phosphate reductase NP_213729.1 742979 D 224324 CDS NP_213730.1 15606351 1193801 744320..744754 1 NC_000918.1 hypothetical protein 744754 1193801 aq_1072 Aquifex aeolicus VF5 hypothetical protein NP_213730.1 744320 D 224324 CDS NP_213731.1 15606352 1193802 744788..745714 1 NC_000918.1 cation efflux system CzcD-like protein 745714 czcD 1193802 czcD Aquifex aeolicus VF5 cation efflux system CzcD-like protein NP_213731.1 744788 D 224324 CDS NP_213732.1 15606353 1193803 745729..746226 1 NC_000918.1 hypothetical protein 746226 1193803 aq_1075 Aquifex aeolicus VF5 hypothetical protein NP_213732.1 745729 D 224324 CDS NP_213733.1 15606354 1193804 746226..747140 1 NC_000918.1 thiosulfate sulfurtransferase 747140 rhdA1 1193804 rhdA1 Aquifex aeolicus VF5 thiosulfate sulfurtransferase NP_213733.1 746226 D 224324 CDS NP_213734.1 15606355 1193805 747481..748146 1 NC_000918.1 hypothetical protein 748146 1193805 aq_1078 Aquifex aeolicus VF5 hypothetical protein NP_213734.1 747481 D 224324 CDS NP_213735.1 15606356 1193806 748376..749626 1 NC_000918.1 hypothetical protein 749626 1193806 aq_1079 Aquifex aeolicus VF5 hypothetical protein NP_213735.1 748376 D 224324 CDS NP_213736.1 15606357 1193807 749630..752287 1 NC_000918.1 hypothetical protein 752287 1193807 aq_1080 Aquifex aeolicus VF5 hypothetical protein NP_213736.1 749630 D 224324 CDS NP_213737.1 15606358 1193808 complement(752277..753917) 1 NC_000918.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from Escherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein 753917 cysD 1193808 cysD Aquifex aeolicus VF5 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein NP_213737.1 752277 R 224324 CDS NP_213738.1 15606359 1193809 754007..755044 1 NC_000918.1 GDP-D-mannose dehydratase 755044 rfbD 1193809 rfbD Aquifex aeolicus VF5 GDP-D-mannose dehydratase NP_213738.1 754007 D 224324 CDS NP_213739.1 15606360 1193810 complement(755047..755415) 1 NC_000918.1 hypothetical protein 755415 1193810 aq_1084 Aquifex aeolicus VF5 hypothetical protein NP_213739.1 755047 R 224324 CDS NP_213740.1 15606361 1193811 complement(756060..757469) 1 NC_000918.1 hypothetical protein 757469 1193811 aq_1085 Aquifex aeolicus VF5 hypothetical protein NP_213740.1 756060 R 224324 CDS NP_213741.1 15606362 1193812 complement(757481..759766) 1 NC_000918.1 hypothetical protein 759766 1193812 aq_1088 Aquifex aeolicus VF5 hypothetical protein NP_213741.1 757481 R 224324 CDS NP_213742.1 15606363 1193813 complement(759811..761007) 1 NC_000918.1 hemolysin 761007 hylA 1193813 hylA Aquifex aeolicus VF5 hemolysin NP_213742.1 759811 R 224324 CDS NP_213743.1 15606364 1193814 761152..762429 1 NC_000918.1 hypothetical protein 762429 1193814 aq_1093 Aquifex aeolicus VF5 hypothetical protein NP_213743.1 761152 D 224324 CDS NP_213744.1 15606365 1193815 complement(762407..763597) 1 NC_000918.1 ABC transporter 763597 abcT4 1193815 abcT4 Aquifex aeolicus VF5 ABC transporter NP_213744.1 762407 R 224324 CDS NP_213745.1 15606366 1193816 complement(763594..764364) 1 NC_000918.1 ABC transporter 764364 abcT3 1193816 abcT3 Aquifex aeolicus VF5 ABC transporter NP_213745.1 763594 R 224324 CDS NP_213746.1 15606367 1193817 complement(764571..766337) 1 NC_000918.1 mannosyltransferase A 766337 mtfA 1193817 mtfA Aquifex aeolicus VF5 mannosyltransferase A NP_213746.1 764571 R 224324 CDS NP_213747.1 15606368 1193818 766601..768295 1 NC_000918.1 ABC transporter 768295 abcT5 1193818 abcT5 Aquifex aeolicus VF5 ABC transporter NP_213747.1 766601 D 224324 CDS NP_213748.1 15606369 1193819 complement(768292..769221) 1 NC_000918.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 769221 fabH 1193819 fabH Aquifex aeolicus VF5 3-oxoacyl-ACP synthase NP_213748.1 768292 R 224324 CDS NP_213749.1 15606370 1193820 complement(769222..770235) 1 NC_000918.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase 770235 plsX 1193820 plsX Aquifex aeolicus VF5 glycerol-3-phosphate acyltransferase NP_213749.1 769222 R 224324 CDS NP_213750.1 15606371 1193821 complement(770235..770426) 1 NC_000918.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 770426 rpmF 1193821 rpmF Aquifex aeolicus VF5 50S ribosomal protein L32 NP_213750.1 770235 R 224324 CDS NP_213751.1 15606372 1193822 complement(770426..770950) 1 NC_000918.1 hypothetical protein 770950 1193822 aq_1103 Aquifex aeolicus VF5 hypothetical protein NP_213751.1 770426 R 224324 CDS NP_213752.1 15606373 1193823 770996..772048 1 NC_000918.1 hypothetical protein 772048 1193823 aq_1104 Aquifex aeolicus VF5 hypothetical protein NP_213752.1 770996 D 224324 CDS NP_213753.1 15606374 1193824 772057..772740 1 NC_000918.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 772740 purQ 1193824 purQ Aquifex aeolicus VF5 phosphoribosylformylglycinamidine synthase I NP_213753.1 772057 D 224324 CDS NP_213754.1 15606375 1193825 772733..773836 1 NC_000918.1 hypothetical protein 773836 1193825 aq_1106 Aquifex aeolicus VF5 hypothetical protein NP_213754.1 772733 D 224324 CDS NP_213755.1 15607139 1194007 773849..774085 1 NC_000918.1 molybdopterin converting factor, small subunit 774085 moaD 1194007 moaD Aquifex aeolicus VF5 molybdopterin converting factor, small subunit NP_213755.1 773849 D 224324 CDS NP_213756.1 15606376 1193826 774106..774621 1 NC_000918.1 glycine cleavage system protein H 774621 gcsH4 1193826 gcsH4 Aquifex aeolicus VF5 glycine cleavage system protein H NP_213756.1 774106 D 224324 CDS NP_213757.1 15606377 1193827 774618..775937 1 NC_000918.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 775937 gcsP2 1193827 gcsP2 Aquifex aeolicus VF5 glycine dehydrogenase subunit 1 NP_213757.1 774618 D 224324 CDS NP_213758.1 15606378 1193828 complement(775923..776378) 1 NC_000918.1 hypothetical protein 776378 1193828 aq_1110 Aquifex aeolicus VF5 hypothetical protein NP_213758.1 775923 R 224324 CDS NP_213759.1 15606379 1193829 776595..777260 1 NC_000918.1 hypothetical protein 777260 1193829 aq_1111 Aquifex aeolicus VF5 hypothetical protein NP_213759.1 776595 D 224324 CDS NP_213760.1 15606380 1192542 777271..778230 1 NC_000918.1 hypothetical protein 778230 1192542 aq_1113 Aquifex aeolicus VF5 hypothetical protein NP_213760.1 777271 D 224324 CDS NP_213761.1 15606381 1192543 778227..780167 1 NC_000918.1 histidine kinase sensor protein 780167 hksP1 1192543 hksP1 Aquifex aeolicus VF5 histidine kinase sensor protein NP_213761.1 778227 D 224324 CDS NP_213762.1 15606382 1192544 780148..781467 1 NC_000918.1 NtrC family transcriptional regulator 781467 ntrC1 1192544 ntrC1 Aquifex aeolicus VF5 NtrC family transcriptional regulator NP_213762.1 780148 D 224324 CDS NP_213763.1 15606383 1192545 781521..782078 1 NC_000918.1 hypothetical protein 782078 1192545 aq_1119 Aquifex aeolicus VF5 hypothetical protein NP_213763.1 781521 D 224324 CDS NP_213764.1 15606384 1192546 782351..782854 1 NC_000918.1 hypothetical protein 782854 1192546 aq_1120 Aquifex aeolicus VF5 hypothetical protein NP_213764.1 782351 D 224324 CDS NP_213765.1 15606385 1192547 782895..783701 1 NC_000918.1 hypothetical protein 783701 1192547 aq_1121 Aquifex aeolicus VF5 hypothetical protein NP_213765.1 782895 D 224324 CDS NP_213766.1 15606386 1192548 complement(783682..786834) 1 NC_000918.1 AcrB/AcrD/AcrF family cation efflux protein 786834 acrD2 1192548 acrD2 Aquifex aeolicus VF5 AcrB/AcrD/AcrF family cation efflux protein NP_213766.1 783682 R 224324 CDS NP_213767.1 15606387 1192549 complement(786841..788835) 1 NC_000918.1 cation transporter E1-E2 family ATPase 788835 ctrA3 1192549 ctrA3 Aquifex aeolicus VF5 cation transporter E1-E2 family ATPase NP_213767.1 786841 R 224324 CDS NP_213768.1 15606388 1192550 complement(788837..789205) 1 NC_000918.1 hypothetical protein 789205 1192550 aq_1127 Aquifex aeolicus VF5 hypothetical protein NP_213768.1 788837 R 224324 CDS NP_213769.1 15606389 1192551 complement(789211..789579) 1 NC_000918.1 hypothetical protein 789579 1192551 aq_1129 Aquifex aeolicus VF5 hypothetical protein NP_213769.1 789211 R 224324 CDS NP_213770.1 15606390 1192552 complement(789593..791176) 1 NC_000918.1 periplasmic cell division protein SufI 791176 sufI 1192552 sufI Aquifex aeolicus VF5 periplasmic cell division protein SufI NP_213770.1 789593 R 224324 CDS NP_213771.1 15606391 1192553 complement(791189..792523) 1 NC_000918.1 cation efflux system CzcB-like protein 792523 czcB1 1192553 czcB1 Aquifex aeolicus VF5 cation efflux system CzcB-like protein NP_213771.1 791189 R 224324 CDS NP_213772.1 15606392 1192554 complement(792520..793698) 1 NC_000918.1 hypothetical protein 793698 1192554 aq_1133 Aquifex aeolicus VF5 hypothetical protein NP_213772.1 792520 R 224324 CDS NP_213773.1 15606393 1192555 complement(793767..794837) 1 NC_000918.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 794837 proB 1192555 proB Aquifex aeolicus VF5 gamma-glutamyl kinase NP_213773.1 793767 R 224324 CDS NP_213774.1 15606394 1192556 794867..795739 1 NC_000918.1 hypothetical protein 795739 1192556 aq_1137 Aquifex aeolicus VF5 hypothetical protein NP_213774.1 794867 D 224324 CDS NP_213775.1 15606395 1192557 795750..796214 1 NC_000918.1 ribose 5-phosphate isomerase B 796214 rpiB 1192557 rpiB Aquifex aeolicus VF5 ribose 5-phosphate isomerase B NP_213775.1 795750 D 224324 CDS NP_213776.1 15606396 1192558 796183..797529 1 NC_000918.1 cell division protein FtsW 797529 ftsW 1192558 ftsW Aquifex aeolicus VF5 cell division protein FtsW NP_213776.1 796183 D 224324 CDS NP_213777.1 15606397 1192559 797533..798738 1 NC_000918.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 798738 argG 1192559 argG Aquifex aeolicus VF5 argininosuccinate synthase NP_213777.1 797533 D 224324 CDS NP_213778.1 15606398 1192560 798771..799841 1 NC_000918.1 hypothetical protein 799841 1192560 aq_1141 Aquifex aeolicus VF5 hypothetical protein NP_213778.1 798771 D 224324 CDS NP_213779.1 15606399 1192561 complement(799806..800855) 1 NC_000918.1 hypothetical protein 800855 1192561 aq_1142 Aquifex aeolicus VF5 hypothetical protein NP_213779.1 799806 R 224324 CDS NP_213780.1 15606400 1192562 800897..801781 1 NC_000918.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 801781 dapA 1192562 dapA Aquifex aeolicus VF5 dihydrodipicolinate synthase NP_213780.1 800897 D 224324 CDS NP_213781.1 15606401 1192563 complement(801764..802810) 1 NC_000918.1 p-aminobenzoate synthetase 802810 pabB 1192563 pabB Aquifex aeolicus VF5 p-aminobenzoate synthetase NP_213781.1 801764 R 224324 CDS NP_213782.1 15606402 1192564 complement(802807..803970) 1 NC_000918.1 1,3 propanediol dehydrogenase 803970 dhaT 1192564 dhaT Aquifex aeolicus VF5 1,3 propanediol dehydrogenase NP_213782.1 802807 R 224324 CDS NP_213783.1 15606403 1192565 complement(803996..805384) 1 NC_000918.1 hypothetical protein 805384 1192565 aq_1148 Aquifex aeolicus VF5 hypothetical protein NP_213783.1 803996 R 224324 CDS NP_213784.1 15606404 1192566 complement(805785..808229) 1 NC_000918.1 hypothetical protein 808229 1192566 aq_1151 Aquifex aeolicus VF5 hypothetical protein NP_213784.1 805785 R 224324 CDS NP_213785.1 15606405 1192567 complement(808278..809525) 1 NC_000918.1 aspartokinase 809525 lysC 1192567 lysC Aquifex aeolicus VF5 aspartokinase NP_213785.1 808278 R 224324 CDS NP_213786.1 15606406 1192568 809561..810691 1 NC_000918.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 810691 metK 1192568 metK Aquifex aeolicus VF5 S-adenosylmethionine synthetase NP_213786.1 809561 D 224324 CDS NP_213787.1 15606407 1192569 complement(810680..811831) 1 NC_000918.1 histidyl-tRNA synthetase 811831 hisS2 1192569 hisS2 Aquifex aeolicus VF5 histidyl-tRNA synthetase NP_213787.1 810680 R 224324 CDS NP_213788.1 15606408 1192570 complement(811828..813516) 1 NC_000918.1 hydrogenase regulation HoxX 813516 hoxX 1192570 hoxX Aquifex aeolicus VF5 hydrogenase regulation HoxX NP_213788.1 811828 R 224324 CDS NP_213789.1 15606409 1192571 complement(813529..814671) 1 NC_000918.1 hydrogenase expression/formation protein HypD 814671 hypD 1192571 hypD Aquifex aeolicus VF5 hydrogenase expression/formation protein HypD NP_213789.1 813529 R 224324 CDS NP_213790.1 15606410 1192572 814948..818481 1 NC_000918.1 catalyzes the magnesium and ATP-dependent positive supercoiling of DNA; contains helicase and topoisomerase domains; reverse gyrase 818481 topG1 1192572 topG1 Aquifex aeolicus VF5 reverse gyrase NP_213790.1 814948 D 224324 CDS NP_213791.1 15606411 1192573 818518..818895 1 NC_000918.1 hypothetical protein 818895 1192573 aq_1163 Aquifex aeolicus VF5 hypothetical protein NP_213791.1 818518 D 224324 CDS NP_213792.1 15606412 1192574 819009..819743 1 NC_000918.1 hypothetical protein 819743 1192574 aq_1166 Aquifex aeolicus VF5 hypothetical protein NP_213792.1 819009 D 224324 CDS NP_213793.1 15606413 1192575 819763..820932 1 NC_000918.1 ferredoxin oxidoreductase subunit alpha 820932 forA2 1192575 forA2 Aquifex aeolicus VF5 ferredoxin oxidoreductase subunit alpha NP_213793.1 819763 D 224324 CDS NP_213794.1 15606414 1192576 820956..821825 1 NC_000918.1 ferredoxin oxidoreductase subunit beta 821825 forB2 1192576 forB2 Aquifex aeolicus VF5 ferredoxin oxidoreductase subunit beta NP_213794.1 820956 D 224324 CDS NP_213795.1 15606415 1192577 821822..822514 1 NC_000918.1 ferredoxin oxidoreductase subunit gamma 822514 forG2 1192577 forG2 Aquifex aeolicus VF5 ferredoxin oxidoreductase subunit gamma NP_213795.1 821822 D 224324 CDS NP_213796.1 15606416 1192578 822528..822764 1 NC_000918.1 ferredoxin 822764 fdx2 1192578 fdx2 Aquifex aeolicus VF5 ferredoxin NP_213796.1 822528 D 224324 CDS NP_213797.1 15606417 1192579 823159..824772 1 NC_000918.1 carbamoyl-phosphate synthase large subunit 824772 carB1 1192579 carB1 Aquifex aeolicus VF5 carbamoyl-phosphate synthase large subunit NP_213797.1 823159 D 224324 CDS NP_213798.1 15606418 1192580 824888..825337 1 NC_000918.1 hypothetical protein 825337 1192580 aq_1173 Aquifex aeolicus VF5 hypothetical protein NP_213798.1 824888 D 224324 CDS NP_213799.1 15606419 1192581 825286..825966 1 NC_000918.1 rare lipoprotein A 825966 rlpA2 1192581 rlpA2 Aquifex aeolicus VF5 rare lipoprotein A NP_213799.1 825286 D 224324 CDS NP_213800.1 15606420 1192582 825994..827391 1 NC_000918.1 amidophosphoribosyltransferase 827391 purF 1192582 purF Aquifex aeolicus VF5 amidophosphoribosyltransferase NP_213800.1 825994 D 224324 CDS NP_213801.1 15606421 1192583 827458..827793 1 NC_000918.1 hypothetical protein 827793 1192583 aq_1176 Aquifex aeolicus VF5 hypothetical protein NP_213801.1 827458 D 224324 CDS NP_213802.1 15606422 1192584 complement(827782..828816) 1 NC_000918.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 828816 murG 1192584 murG Aquifex aeolicus VF5 UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_213802.1 827782 R 224324 CDS NP_213803.1 15606423 1192585 828841..829344 1 NC_000918.1 phosphoribosylaminoimidazole carboxylase 829344 purE 1192585 purE Aquifex aeolicus VF5 phosphoribosylaminoimidazole carboxylase NP_213803.1 828841 D 224324 CDS NP_213804.1 15606424 1192586 829334..830590 1 NC_000918.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 830590 sahH 1192586 sahH Aquifex aeolicus VF5 S-adenosyl-L-homocysteine hydrolase NP_213804.1 829334 D 224324 CDS NP_213805.1 15606425 1192587 complement(830595..832064) 1 NC_000918.1 flagellar M-ring protein 832064 fliF 1192587 fliF Aquifex aeolicus VF5 flagellar M-ring protein NP_213805.1 830595 R 224324 CDS NP_213806.1 15606426 1192588 complement(832066..832347) 1 NC_000918.1 flagellar hook-basal body protein 832347 fliE 1192588 fliE Aquifex aeolicus VF5 flagellar hook-basal body protein NP_213806.1 832066 R 224324 CDS NP_213807.1 15606427 1192589 complement(832338..832742) 1 NC_000918.1 flagellar biosynthesis FlgC 832742 flgC 1192589 flgC Aquifex aeolicus VF5 flagellar biosynthesis FlgC NP_213807.1 832338 R 224324 CDS NP_213808.1 15606428 1192590 complement(832739..833113) 1 NC_000918.1 flagellar basal body rod protein FlgB 833113 flgB 1192590 flgB Aquifex aeolicus VF5 flagellar basal body rod protein FlgB NP_213808.1 832739 R 224324 CDS NP_213809.1 15606429 1192591 complement(833114..834901) 1 NC_000918.1 hypothetical protein 834901 1192591 aq_1185 Aquifex aeolicus VF5 hypothetical protein NP_213809.1 833114 R 224324 CDS NP_213810.1 15606430 1192592 complement(834837..836057) 1 NC_000918.1 hypothetical protein 836057 1192592 aq_1186 Aquifex aeolicus VF5 hypothetical protein NP_213810.1 834837 R 224324 CDS NP_213811.1 15606431 1192593 complement(836072..836575) 1 NC_000918.1 hypothetical protein 836575 1192593 aq_1187 Aquifex aeolicus VF5 hypothetical protein NP_213811.1 836072 R 224324 CDS NP_213812.1 15606432 1192594 836624..837091 1 NC_000918.1 hypothetical protein 837091 1192594 aq_1188 Aquifex aeolicus VF5 hypothetical protein NP_213812.1 836624 D 224324 CDS NP_213813.1 15606433 1192595 837078..838865 1 NC_000918.1 penicillin binding protein 2 838865 pbpA1 1192595 pbpA1 Aquifex aeolicus VF5 penicillin binding protein 2 NP_213813.1 837078 D 224324 CDS NP_213814.1 15606434 1192596 complement(838862..839845) 1 NC_000918.1 hypothetical protein 839845 1192596 aq_1191 Aquifex aeolicus VF5 hypothetical protein NP_213814.1 838862 R 224324 CDS NP_213815.1 15606435 1192597 839920..840159 1 NC_000918.1 ferredoxin 840159 fdx3 1192597 fdx3 Aquifex aeolicus VF5 ferredoxin NP_213815.1 839920 D 224324 CDS NP_213816.1 15606436 1192598 840172..840741 1 NC_000918.1 hypothetical protein 840741 1192598 aq_1192 Aquifex aeolicus VF5 hypothetical protein NP_213816.1 840172 D 224324 CDS NP_213817.1 15606437 1192599 840741..841283 1 NC_000918.1 hypothetical protein 841283 1192599 aq_1194 Aquifex aeolicus VF5 hypothetical protein NP_213817.1 840741 D 224324 CDS NP_213818.1 15606438 1192600 841295..842509 1 NC_000918.1 ferredoxin oxidoreductase subunit alpha 842509 forA1 1192600 forA1 Aquifex aeolicus VF5 ferredoxin oxidoreductase subunit alpha NP_213818.1 841295 D 224324 CDS NP_213819.1 15606439 1192601 842499..843359 1 NC_000918.1 ferredoxin oxidoreductase subunit beta 843359 forB1 1192601 forB1 Aquifex aeolicus VF5 ferredoxin oxidoreductase subunit beta NP_213819.1 842499 D 224324 CDS NP_213820.1 15606440 1192602 843356..844081 1 NC_000918.1 ferredoxin oxidoreductase subunit gamma 844081 forG1 1192602 forG1 Aquifex aeolicus VF5 ferredoxin oxidoreductase subunit gamma NP_213820.1 843356 D 224324 CDS NP_213821.1 15606441 1192603 complement(844484..844822) 1 NC_000918.1 hypothetical protein 844822 1192603 aq_1201 Aquifex aeolicus VF5 hypothetical protein NP_213821.1 844484 R 224324 CDS NP_213822.1 15606442 1192604 844743..846536 1 NC_000918.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 846536 lysS 1192604 lysS Aquifex aeolicus VF5 lysyl-tRNA synthetase NP_213822.1 844743 D 224324 CDS NP_213823.1 15606443 1192605 complement(846533..847906) 1 NC_000918.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 847906 thiC 1192605 thiC Aquifex aeolicus VF5 thiamine biosynthesis protein ThiC NP_213823.1 846533 R 224324 CDS NP_213824.1 15606444 1192606 847969..848940 1 NC_000918.1 acetyl-CoA carboxylase subunit alpha 848940 accA 1192606 accA Aquifex aeolicus VF5 acetyl-CoA carboxylase subunit alpha NP_213824.1 847969 D 224324 CDS NP_213825.1 15606445 1192607 complement(848924..849358) 1 NC_000918.1 FUR family transcriptional regulator 849358 furR1 1192607 furR1 Aquifex aeolicus VF5 FUR family transcriptional regulator NP_213825.1 848924 R 224324 CDS NP_213826.1 15606446 1192608 complement(849405..850667) 1 NC_000918.1 diaminopimelate decarboxylase 850667 lysA 1192608 lysA Aquifex aeolicus VF5 diaminopimelate decarboxylase NP_213826.1 849405 R 224324 CDS NP_213827.1 15606447 1192609 complement(850689..851423) 1 NC_000918.1 hypothetical protein 851423 1192609 aq_1210 Aquifex aeolicus VF5 hypothetical protein NP_213827.1 850689 R 224324 CDS NP_213828.1 15606448 1192610 851461..852072 1 NC_000918.1 hypothetical protein 852072 1192610 aq_1211 Aquifex aeolicus VF5 hypothetical protein NP_213828.1 851461 D 224324 CDS NP_213829.1 15606449 1192611 852069..854105 1 NC_000918.1 flagellar export protein 854105 flhA 1192611 flhA Aquifex aeolicus VF5 flagellar export protein NP_213829.1 852069 D 224324 CDS NP_213830.1 15606450 1192612 854095..855216 1 NC_000918.1 flagellar biosynthesis FlhF 855216 flhF 1192612 flhF Aquifex aeolicus VF5 flagellar biosynthesis FlhF NP_213830.1 854095 D 224324 CDS NP_213831.1 15606451 1192613 855179..856015 1 NC_000918.1 septum site-determining protein MinD 856015 minD1 1192613 minD1 Aquifex aeolicus VF5 septum site-determining protein MinD NP_213831.1 855179 D 224324 CDS NP_213832.1 15606452 1192614 856012..856722 1 NC_000918.1 RNA polymerase sigma factor FliA 856722 fliA 1192614 fliA Aquifex aeolicus VF5 RNA polymerase sigma factor FliA NP_213832.1 856012 D 224324 CDS NP_213833.1 15606453 1192615 complement(856709..857266) 1 NC_000918.1 hypothetical protein 857266 1192615 aq_1219 Aquifex aeolicus VF5 hypothetical protein NP_213833.1 856709 R 224324 CDS NP_213834.1 15606454 1192616 complement(857305..858804) 1 NC_000918.1 hypothetical protein 858804 1192616 aq_1220 Aquifex aeolicus VF5 hypothetical protein NP_213834.1 857305 R 224324 CDS NP_213835.1 15606455 1192617 859084..860505 1 NC_000918.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 860505 gltX 1192617 gltX Aquifex aeolicus VF5 glutamyl-tRNA synthetase NP_213835.1 859084 D 224324 CDS NP_213836.1 15606456 1192618 860502..861191 1 NC_000918.1 ABC transporter 861191 abcT1 1192618 abcT1 Aquifex aeolicus VF5 ABC transporter NP_213836.1 860502 D 224324 CDS NP_213837.1 15606457 1192619 complement(861188..861895) 1 NC_000918.1 hypothetical protein 861895 1192619 aq_1223 Aquifex aeolicus VF5 hypothetical protein NP_213837.1 861188 R 224324 CDS NP_213838.1 15606458 1192620 862048..863118 1 NC_000918.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 863118 mnmA 1192620 mnmA Aquifex aeolicus VF5 tRNA-specific 2-thiouridylase MnmA NP_213838.1 862048 D 224324 CDS NP_213839.1 15606459 1192621 863160..864362 1 NC_000918.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; S-adenosylmethionine synthetase 864362 1192621 aq_1226 Aquifex aeolicus VF5 S-adenosylmethionine synthetase NP_213839.1 863160 D 224324 CDS NP_213840.1 15606460 1192622 864401..865579 1 NC_000918.1 major facilitator transporter 865579 mffT2 1192622 mffT2 Aquifex aeolicus VF5 major facilitator transporter NP_213840.1 864401 D 224324 CDS NP_213841.1 15606461 1192623 complement(865609..866352) 1 NC_000918.1 hypothetical protein 866352 1192623 aq_1230 Aquifex aeolicus VF5 hypothetical protein NP_213841.1 865609 R 224324 CDS NP_213842.1 15606462 1192624 complement(866714..867727) 1 NC_000918.1 dimethylsulfoxide reductase subunit C 867727 dmsC 1192624 dmsC Aquifex aeolicus VF5 dimethylsulfoxide reductase subunit C NP_213842.1 866714 R 224324 CDS NP_213843.1 15606463 1192625 complement(867743..868507) 1 NC_000918.1 DMSO reductase subunit B 868507 dmsB1 1192625 dmsB1 Aquifex aeolicus VF5 DMSO reductase subunit B NP_213843.1 867743 R 224324 CDS NP_213844.1 15606464 1192626 complement(868520..871474) 1 NC_000918.1 dimethylsulfoxide reductase subunit A 871474 dmsA 1192626 dmsA Aquifex aeolicus VF5 dimethylsulfoxide reductase subunit A NP_213844.1 868520 R 224324 CDS NP_213845.1 15606465 1192627 871498..872904 1 NC_000918.1 hypothetical protein 872904 1192627 aq_1236 Aquifex aeolicus VF5 hypothetical protein NP_213845.1 871498 D 224324 CDS NP_213846.1 15606466 1192628 873066..873629 1 NC_000918.1 siroheme synthase 873629 cysG 1192628 cysG Aquifex aeolicus VF5 siroheme synthase NP_213846.1 873066 D 224324 CDS NP_213847.1 15606467 1192629 complement(873615..874163) 1 NC_000918.1 hypothetical protein 874163 1192629 aq_1238 Aquifex aeolicus VF5 hypothetical protein NP_213847.1 873615 R 224324 CDS NP_213848.1 15606468 1192630 complement(874193..874528) 1 NC_000918.1 hypothetical protein 874528 1192630 aq_1239 Aquifex aeolicus VF5 hypothetical protein NP_213848.1 874193 R 224324 CDS NP_213849.1 15606469 1192631 complement(874528..875253) 1 NC_000918.1 alcohol dehydrogenase 875253 adh2 1192631 adh2 Aquifex aeolicus VF5 alcohol dehydrogenase NP_213849.1 874528 R 224324 CDS NP_213850.1 15606470 1192632 complement(875250..875702) 1 NC_000918.1 hypothetical protein 875702 1192632 aq_1241 Aquifex aeolicus VF5 hypothetical protein NP_213850.1 875250 R 224324 CDS NP_213851.1 15606471 1192633 complement(875699..877987) 1 NC_000918.1 DNA mismatch repair protein MutS 877987 mutS2 1192633 mutS2 Aquifex aeolicus VF5 DNA mismatch repair protein MutS NP_213851.1 875699 R 224324 CDS NP_213852.1 15606472 1192726 complement(877994..878617) 1 NC_000918.1 hypothetical protein 878617 1192726 aq_1244 Aquifex aeolicus VF5 hypothetical protein NP_213852.1 877994 R 224324 CDS NP_213853.1 15606473 1192727 complement(878614..879615) 1 NC_000918.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 879615 ilvC 1192727 ilvC Aquifex aeolicus VF5 ketol-acid reductoisomerase NP_213853.1 878614 R 224324 CDS NP_213854.1 15606474 1192728 879682..880335 1 NC_000918.1 hypothetical protein 880335 1192728 aq_1247 Aquifex aeolicus VF5 hypothetical protein NP_213854.1 879682 D 224324 CDS NP_213855.1 15606475 1192729 880332..881027 1 NC_000918.1 hypothetical protein 881027 1192729 aq_1248 Aquifex aeolicus VF5 hypothetical protein NP_213855.1 880332 D 224324 CDS NP_213856.1 15606476 1192730 880975..881754 1 NC_000918.1 phosphatidate cytidylyltransferase 881754 cds 1192730 cds Aquifex aeolicus VF5 phosphatidate cytidylyltransferase NP_213856.1 880975 D 224324 CDS NP_213857.1 15606477 1192731 881726..882241 1 NC_000918.1 hypothetical protein 882241 1192731 aq_1250 Aquifex aeolicus VF5 hypothetical protein NP_213857.1 881726 D 224324 CDS NP_213858.1 15606478 1192732 complement(882667..883122) 1 NC_000918.1 hypothetical protein 883122 1192732 aq_1253 Aquifex aeolicus VF5 hypothetical protein NP_213858.1 882667 R 224324 CDS NP_213859.1 15606479 1192733 883164..883472 1 NC_000918.1 hypothetical protein 883472 1192733 aq_1254 Aquifex aeolicus VF5 hypothetical protein NP_213859.1 883164 D 224324 CDS NP_213860.1 15606480 1192734 complement(883469..885538) 1 NC_000918.1 ferrous iron transport protein B 885538 feoB 1192734 feoB Aquifex aeolicus VF5 ferrous iron transport protein B NP_213860.1 883469 R 224324 CDS NP_213861.1 15606481 1192735 complement(885548..886477) 1 NC_000918.1 hypothetical protein 886477 1192735 aq_1256 Aquifex aeolicus VF5 hypothetical protein NP_213861.1 885548 R 224324 CDS NP_213862.1 15606482 1192736 886771..888264 1 NC_000918.1 methionyl-tRNA synthetase subunit alpha 888264 metG 1192736 metG Aquifex aeolicus VF5 methionyl-tRNA synthetase subunit alpha NP_213862.1 886771 D 224324 CDS NP_213863.1 15606483 1192737 888261..889127 1 NC_000918.1 hypothetical protein 889127 1192737 aq_1258 Aquifex aeolicus VF5 hypothetical protein NP_213863.1 888261 D 224324 CDS NP_213864.1 15606484 1192738 889204..890514 1 NC_000918.1 hypothetical protein 890514 1192738 aq_1259 Aquifex aeolicus VF5 hypothetical protein NP_213864.1 889204 D 224324 CDS NP_213865.1 15606485 1192739 890580..892274 1 NC_000918.1 hypothetical protein 892274 1192739 aq_1262 Aquifex aeolicus VF5 hypothetical protein NP_213865.1 890580 D 224324 CDS NP_213866.1 15606486 1192740 892238..892792 1 NC_000918.1 hypothetical protein 892792 1192740 aq_1263 Aquifex aeolicus VF5 hypothetical protein NP_213866.1 892238 D 224324 CDS NP_213867.1 15606487 1192741 892789..893709 1 NC_000918.1 hypothetical protein 893709 1192741 aq_1264 Aquifex aeolicus VF5 hypothetical protein NP_213867.1 892789 D 224324 CDS NP_213868.1 15606488 1192742 complement(893687..895354) 1 NC_000918.1 carbon starvation protein A 895354 cstA 1192742 cstA Aquifex aeolicus VF5 carbon starvation protein A NP_213868.1 893687 R 224324 CDS NP_213869.1 15606489 1192743 895686..896408 1 NC_000918.1 hypothetical protein 896408 1192743 aq_1267 Aquifex aeolicus VF5 hypothetical protein NP_213869.1 895686 D 224324 CDS NP_213870.1 15606490 1192744 896480..898297 1 NC_000918.1 high affinity sulfate transporter 898297 hvsT 1192744 hvsT Aquifex aeolicus VF5 high affinity sulfate transporter NP_213870.1 896480 D 224324 CDS NP_213871.1 15606491 1192745 898446..899048 1 NC_000918.1 hypothetical protein 899048 1192745 aq_1270 Aquifex aeolicus VF5 hypothetical protein NP_213871.1 898446 D 224324 CDS NP_213872.1 15606492 1192746 899259..900560 1 NC_000918.1 processing protease 900560 mpp 1192746 mpp Aquifex aeolicus VF5 processing protease NP_213872.1 899259 D 224324 CDS NP_213873.1 15606493 1192747 complement(900570..900899) 1 NC_000918.1 hypothetical protein 900899 1192747 aq_1272 Aquifex aeolicus VF5 hypothetical protein NP_213873.1 900570 R 224324 CDS NP_213874.1 15606494 1192748 complement(900887..901807) 1 NC_000918.1 hypothetical protein 901807 1192748 aq_1273 Aquifex aeolicus VF5 hypothetical protein NP_213874.1 900887 R 224324 CDS NP_213875.1 15606495 1192749 complement(901756..903132) 1 NC_000918.1 cytoplasmic axial filament protein 903132 cafA 1192749 cafA Aquifex aeolicus VF5 cytoplasmic axial filament protein NP_213875.1 901756 R 224324 CDS NP_213876.1 15606496 1192750 903044..903961 1 NC_000918.1 hypothetical protein 903961 1192750 aq_1276 Aquifex aeolicus VF5 hypothetical protein NP_213876.1 903044 D 224324 CDS NP_213877.1 15606497 1192751 complement(903946..904518) 1 NC_000918.1 hypothetical protein 904518 1192751 aq_1277 Aquifex aeolicus VF5 hypothetical protein NP_213877.1 903946 R 224324 CDS NP_213878.1 15606498 1192752 904557..905777 1 NC_000918.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 905777 hemA 1192752 hemA Aquifex aeolicus VF5 glutamyl-tRNA reductase NP_213878.1 904557 D 224324 CDS NP_213879.1 15606499 1192753 906163..907440 1 NC_000918.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 907440 murA 1192753 murA Aquifex aeolicus VF5 UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_213879.1 906163 D 224324 CDS NP_213880.1 15606500 1192754 complement(907490..907924) 1 NC_000918.1 small heat shock protein (class I) 907924 hspC 1192754 hspC Aquifex aeolicus VF5 small heat shock protein (class I) NP_213880.1 907490 R 224324 CDS NP_213881.1 15606501 1192755 complement(907985..909169) 1 NC_000918.1 fimbrial assembly protein PilC2 909169 pilC2 1192755 pilC2 Aquifex aeolicus VF5 fimbrial assembly protein PilC2 NP_213881.1 907985 R 224324 CDS NP_213882.1 15606502 1192756 complement(909166..910011) 1 NC_000918.1 hypothetical protein 910011 1192756 aq_1286 Aquifex aeolicus VF5 hypothetical protein NP_213882.1 909166 R 224324 CDS NP_213883.1 15606503 1192757 complement(910008..910667) 1 NC_000918.1 hypothetical protein 910667 1192757 aq_1287 Aquifex aeolicus VF5 hypothetical protein NP_213883.1 910008 R 224324 CDS NP_213884.1 15606504 1192758 complement(910633..912510) 1 NC_000918.1 general secretion pathway protein D 912510 gspD 1192758 gspD Aquifex aeolicus VF5 general secretion pathway protein D NP_213884.1 910633 R 224324 CDS NP_213885.1 15606505 1192759 complement(912896..914194) 1 NC_000918.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 914194 purA 1192759 purA Aquifex aeolicus VF5 adenylosuccinate synthetase NP_213885.1 912896 R 224324 CDS NP_213886.1 15606506 1192760 complement(914223..914759) 1 NC_000918.1 THEP1; Aquifex aeolicus protein exhibits ATPase and GTPase activity; crystal structure shows RecA-like fold; NTPase 914759 1192760 aq_1292 Aquifex aeolicus VF5 NTPase NP_213886.1 914223 R 224324 CDS NP_213887.1 15606507 1192761 914828..917431 1 NC_000918.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 917431 alaS 1192761 alaS Aquifex aeolicus VF5 alanyl-tRNA synthetase NP_213887.1 914828 D 224324 CDS NP_213888.1 15606508 1192762 917436..917906 1 NC_000918.1 hypothetical protein 917906 1192762 aq_1295 Aquifex aeolicus VF5 hypothetical protein NP_213888.1 917436 D 224324 CDS NP_213889.1 15606509 1192763 918003..920435 1 NC_000918.1 ATP-dependent Clp protease 920435 clpC 1192763 clpC Aquifex aeolicus VF5 ATP-dependent Clp protease NP_213889.1 918003 D 224324 CDS NP_213890.1 15606510 1192764 920473..922809 1 NC_000918.1 outer membrane protein 922809 omp 1192764 omp Aquifex aeolicus VF5 outer membrane protein NP_213890.1 920473 D 224324 CDS NP_213891.1 15606511 1192765 complement(922835..923047) 1 NC_000918.1 cold shock protein 923047 cspC 1192765 cspC Aquifex aeolicus VF5 cold shock protein NP_213891.1 922835 R 224324 CDS NP_213892.1 15606512 1192766 complement(923151..923867) 1 NC_000918.1 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 923867 hisA 1192766 hisA Aquifex aeolicus VF5 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase NP_213892.1 923151 R 224324 CDS NP_213893.1 15606513 1192767 complement(923864..924619) 1 NC_000918.1 dihydroorotate dehydrogenase electron transfer subunit 924619 pyrDB 1192767 pyrDB Aquifex aeolicus VF5 dihydroorotate dehydrogenase electron transfer subunit NP_213893.1 923864 R 224324 CDS NP_213894.1 15606514 1192768 924687..925997 1 NC_000918.1 succinyl-CoA ligase subunit beta 925997 sucC1 1192768 sucC1 Aquifex aeolicus VF5 succinyl-CoA ligase subunit beta NP_213894.1 924687 D 224324 CDS NP_213895.1 15606515 1192769 926031..927167 1 NC_000918.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 927167 tgt 1192769 tgt Aquifex aeolicus VF5 queuine tRNA-ribosyltransferase NP_213895.1 926031 D 224324 CDS NP_213896.1 15606516 1192770 complement(927151..928044) 1 NC_000918.1 homoserine kinase 928044 thrB 1192770 thrB Aquifex aeolicus VF5 homoserine kinase NP_213896.1 927151 R 224324 CDS NP_213897.1 15606517 1192771 928429..928785 1 NC_000918.1 NADH dehydrogenase I subunit A 928785 nuoA2 1192771 nuoA2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit A NP_213897.1 928429 D 224324 CDS NP_213898.1 15606518 1192772 928798..929337 1 NC_000918.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 929337 nuoB 1192772 nuoB Aquifex aeolicus VF5 NADH dehydrogenase subunit B NP_213898.1 928798 D 224324 CDS NP_213899.1 15606519 1192773 929347..931107 1 NC_000918.1 NADH dehydrogenase I subunit D 931107 nuoD2 1192773 nuoD2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit D NP_213899.1 929347 D 224324 CDS NP_213900.1 15606520 1192774 931120..932130 1 NC_000918.1 NADH dehydrogenase I subunit H 932130 nuoH1 1192774 nuoH1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit H NP_213900.1 931120 D 224324 CDS NP_213901.1 15606521 1192775 932142..932747 1 NC_000918.1 NADH dehydrogenase I subunit I 932747 nuoI1 1192775 nuoI1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit I NP_213901.1 932142 D 224324 CDS NP_213902.1 15606522 1192776 932735..933223 1 NC_000918.1 NADH dehydrogenase I subunit J 933223 nuoJ1 1192776 nuoJ1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit J NP_213902.1 932735 D 224324 CDS NP_213903.1 15606523 1192777 933233..933535 1 NC_000918.1 NADH dehydrogenase I subunit K 933535 nuoK1 1192777 nuoK1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit K NP_213903.1 933233 D 224324 CDS NP_213904.1 15606524 1192778 933532..935400 1 NC_000918.1 NADH dehydrogenase I subunit L 935400 nuoL1 1192778 nuoL1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit L NP_213904.1 933532 D 224324 CDS NP_213905.1 15606525 1192779 935400..936875 1 NC_000918.1 NADH dehydrogenase I subunit M 936875 nuoM1 1192779 nuoM1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit M NP_213905.1 935400 D 224324 CDS NP_213906.1 15606526 1192780 936880..938274 1 NC_000918.1 NADH dehydrogenase I subunit N 938274 nuoN1 1192780 nuoN1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit N NP_213906.1 936880 D 224324 CDS NP_213907.1 15606527 1192781 938284..938925 1 NC_000918.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 938925 ispD 1192781 ispD Aquifex aeolicus VF5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NP_213907.1 938284 D 224324 CDS NP_213908.1 15606528 1192782 complement(938922..939500) 1 NC_000918.1 hypothetical protein 939500 1192782 aq_1324 Aquifex aeolicus VF5 hypothetical protein NP_213908.1 938922 R 224324 CDS NP_213909.1 15606529 1192783 complement(939497..939925) 1 NC_000918.1 molybdopterin-guainine dinucleotide biosynthesis protein B 939925 mobB 1192783 mobB Aquifex aeolicus VF5 molybdopterin-guainine dinucleotide biosynthesis protein B NP_213909.1 939497 R 224324 CDS NP_213910.1 15606530 1192784 939955..940638 1 NC_000918.1 hypothetical protein 940638 1192784 aq_1327 Aquifex aeolicus VF5 hypothetical protein NP_213910.1 939955 D 224324 CDS NP_213911.1 15606531 1192785 complement(940635..942929) 1 NC_000918.1 hypothetical protein 942929 1192785 aq_1328 Aquifex aeolicus VF5 hypothetical protein NP_213911.1 940635 R 224324 CDS NP_213912.1 15606532 1192786 942990..943805 1 NC_000918.1 molybdopterin biosynthesis protein MoeB 943805 moeB 1192786 moeB Aquifex aeolicus VF5 molybdopterin biosynthesis protein MoeB NP_213912.1 942990 D 224324 CDS NP_213913.1 15606533 1192787 943806..945002 1 NC_000918.1 proton/sodium-glutamate symport protein 945002 gltP 1192787 gltP Aquifex aeolicus VF5 proton/sodium-glutamate symport protein NP_213913.1 943806 D 224324 CDS NP_213914.1 15606534 1192788 945014..946060 1 NC_000918.1 cation efflux system CzcB-like protein 946060 czcB2 1192788 czcB2 Aquifex aeolicus VF5 cation efflux system CzcB-like protein NP_213914.1 945014 D 224324 CDS NP_213915.1 15606535 1192789 946057..947304 1 NC_000918.1 hypothetical protein 947304 1192789 aq_1332 Aquifex aeolicus VF5 hypothetical protein NP_213915.1 946057 D 224324 CDS NP_213916.1 15606536 1192790 complement(947293..948198) 1 NC_000918.1 hypothetical protein 948198 1192790 aq_1333 Aquifex aeolicus VF5 hypothetical protein NP_213916.1 947293 R 224324 CDS NP_213917.1 15606537 1192791 complement(948474..950069) 1 NC_000918.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 950069 pyrG 1192791 pyrG Aquifex aeolicus VF5 CTP synthetase NP_213917.1 948474 R 224324 CDS NP_213918.1 15606538 1192792 950129..951094 1 NC_000918.1 nucleotide sugar epimerase 951094 nse 1192792 nse Aquifex aeolicus VF5 nucleotide sugar epimerase NP_213918.1 950129 D 224324 CDS NP_213919.1 15606539 1192793 complement(951091..952215) 1 NC_000918.1 hypothetical protein 952215 1192793 aq_1336 Aquifex aeolicus VF5 hypothetical protein NP_213919.1 951091 R 224324 CDS NP_213920.1 15606540 1192794 complement(952212..953450) 1 NC_000918.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 953450 clpX 1192794 clpX Aquifex aeolicus VF5 ATP-dependent protease ATP-binding subunit ClpX NP_213920.1 952212 R 224324 CDS NP_213921.1 15606541 1192795 complement(953470..954075) 1 NC_000918.1 ATP-dependent Clp protease proteolytic subunit 954075 clpP 1192795 clpP Aquifex aeolicus VF5 ATP-dependent Clp protease proteolytic subunit NP_213921.1 953470 R 224324 CDS NP_213922.1 15606542 1192796 complement(954053..955489) 1 NC_000918.1 trigger factor 955489 tig 1192796 tig Aquifex aeolicus VF5 trigger factor NP_213922.1 954053 R 224324 CDS NP_213923.1 15606543 1192797 complement(955513..956154) 1 NC_000918.1 phosphoglycolate phosphatase 956154 gph 1192797 gph Aquifex aeolicus VF5 phosphoglycolate phosphatase NP_213923.1 955513 R 224324 CDS NP_213924.1 15606544 1192798 complement(956151..956633) 1 NC_000918.1 hypothetical protein 956633 1192798 aq_1343 Aquifex aeolicus VF5 hypothetical protein NP_213924.1 956151 R 224324 CDS NP_213925.1 15606545 1192799 957037..957741 1 NC_000918.1 hypothetical protein 957741 1192799 aq_1345 Aquifex aeolicus VF5 hypothetical protein NP_213925.1 957037 D 224324 CDS NP_213926.1 15606546 1192800 957743..958273 1 NC_000918.1 hypothetical protein 958273 1192800 aq_1347 Aquifex aeolicus VF5 hypothetical protein NP_213926.1 957743 D 224324 CDS NP_213927.1 15606547 1192801 958188..958757 1 NC_000918.1 hypothetical protein 958757 1192801 aq_1348 Aquifex aeolicus VF5 hypothetical protein NP_213927.1 958188 D 224324 CDS NP_213928.1 15606548 1192802 958754..959560 1 NC_000918.1 hypothetical protein 959560 1192802 aq_1349 Aquifex aeolicus VF5 hypothetical protein NP_213928.1 958754 D 224324 CDS NP_213929.1 15606549 1192803 959557..961038 1 NC_000918.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 961038 1192803 aq_1350 Aquifex aeolicus VF5 spermidine synthase NP_213929.1 959557 D 224324 CDS NP_213930.1 15606550 1192804 961064..962110 1 NC_000918.1 phosphate starvation-inducible protein 962110 phoH 1192804 phoH Aquifex aeolicus VF5 phosphate starvation-inducible protein NP_213930.1 961064 D 224324 CDS NP_213931.1 15606551 1192805 962034..962486 1 NC_000918.1 hypothetical protein 962486 1192805 aq_1354 Aquifex aeolicus VF5 hypothetical protein NP_213931.1 962034 D 224324 CDS NP_213932.1 15606552 1192806 complement(962453..963283) 1 NC_000918.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 963283 lipA 1192806 lipA Aquifex aeolicus VF5 lipoyl synthase NP_213932.1 962453 R 224324 CDS NP_213933.1 15606553 1192807 963309..963743 1 NC_000918.1 hypothetical protein 963743 1192807 aq_1356 Aquifex aeolicus VF5 hypothetical protein NP_213933.1 963309 D 224324 CDS NP_213934.1 15606554 1192808 963860..965266 1 NC_000918.1 cytochrome oxidase d subunit I 965266 cydA 1192808 cydA Aquifex aeolicus VF5 cytochrome oxidase d subunit I NP_213934.1 963860 D 224324 CDS NP_213935.1 15606555 1192809 965268..966368 1 NC_000918.1 cytochrome oxidase d subunit II 966368 cydB 1192809 cydB Aquifex aeolicus VF5 cytochrome oxidase d subunit II NP_213935.1 965268 D 224324 CDS NP_213936.1 15606556 1192810 complement(966349..966894) 1 NC_000918.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate; acetyltransferase 966894 1192810 aq_1359 Aquifex aeolicus VF5 acetyltransferase NP_213936.1 966349 R 224324 CDS NP_213937.1 15606557 1192811 complement(966852..968216) 1 NC_000918.1 UDP-N-acetylmuramate-alanine ligase 968216 murC 1192811 murC Aquifex aeolicus VF5 UDP-N-acetylmuramate-alanine ligase NP_213937.1 966852 R 224324 CDS NP_213938.1 15606558 1192812 complement(968216..969247) 1 NC_000918.1 alcohol dehydrogenase 969247 adh1 1192812 adh1 Aquifex aeolicus VF5 alcohol dehydrogenase NP_213938.1 968216 R 224324 CDS NP_213939.1 15606559 1192813 complement(969261..969725) 1 NC_000918.1 biotin carboxyl carrier protein 969725 accB 1192813 accB Aquifex aeolicus VF5 biotin carboxyl carrier protein NP_213939.1 969261 R 224324 CDS NP_213940.1 15606560 1192814 complement(969722..970300) 1 NC_000918.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 970300 efp 1192814 efp Aquifex aeolicus VF5 elongation factor P NP_213940.1 969722 R 224324 CDS NP_213941.1 15606561 1192815 970488..971987 1 NC_000918.1 hypothetical protein 971987 1192815 aq_1365 Aquifex aeolicus VF5 hypothetical protein NP_213941.1 970488 D 224324 CDS NP_213942.1 15606562 1192816 complement(972096..972656) 1 NC_000918.1 thiamine phosphate synthase 972656 thiE1 1192816 thiE1 Aquifex aeolicus VF5 thiamine phosphate synthase NP_213942.1 972096 R 224324 CDS NP_213943.1 15606563 1192817 complement(972668..973954) 1 NC_000918.1 glucose-1-phosphate thymidylyltransferase 973954 spsI 1192817 spsI Aquifex aeolicus VF5 glucose-1-phosphate thymidylyltransferase NP_213943.1 972668 R 224324 CDS NP_213944.1 15606564 1192910 complement(973969..974475) 1 NC_000918.1 glycerol-3-phosphate cytidyltransferase 974475 tagD2 1192910 tagD2 Aquifex aeolicus VF5 glycerol-3-phosphate cytidyltransferase NP_213944.1 973969 R 224324 CDS NP_213945.1 15606565 1192911 974450..975232 1 NC_000918.1 hypothetical protein 975232 1192911 aq_1369 Aquifex aeolicus VF5 hypothetical protein NP_213945.1 974450 D 224324 CDS NP_213946.1 15606566 1192912 975229..975744 1 NC_000918.1 rare lipoprotein A 975744 rlpA1 1192912 rlpA1 Aquifex aeolicus VF5 rare lipoprotein A NP_213946.1 975229 D 224324 CDS NP_213947.1 15606567 1192913 975755..977128 1 NC_000918.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 977128 argH 1192913 argH Aquifex aeolicus VF5 argininosuccinate lyase NP_213947.1 975755 D 224324 CDS NP_213950.1 15606570 1192916 978259..978885 1 NC_000918.1 NADH dehydrogenase I subunit I 978885 nuoI2 1192916 nuoI2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit I NP_213950.1 978259 D 224324 CDS NP_213951.1 15606571 1192917 978882..979418 1 NC_000918.1 NADH dehydrogenase I subunit J 979418 nuoJ2 1192917 nuoJ2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit J NP_213951.1 978882 D 224324 CDS NP_213952.1 15606572 1192918 979399..979707 1 NC_000918.1 NADH dehydrogenase I subunit K 979707 nuoK2 1192918 nuoK2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit K NP_213952.1 979399 D 224324 CDS NP_213953.1 15606573 1192919 979710..981644 1 NC_000918.1 NADH dehydrogenase I subunit L 981644 nuoL3 1192919 nuoL3 Aquifex aeolicus VF5 NADH dehydrogenase I subunit L NP_213953.1 979710 D 224324 CDS NP_213954.1 15606574 1192920 981656..983161 1 NC_000918.1 NADH dehydrogenase I subunit M 983161 nuoM2 1192920 nuoM2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit M NP_213954.1 981656 D 224324 CDS NP_213955.1 15606575 1192921 983175..984641 1 NC_000918.1 NADH dehydrogenase I subunit N 984641 nuoN2 1192921 nuoN2 Aquifex aeolicus VF5 NADH dehydrogenase I subunit N NP_213955.1 983175 D 224324 CDS NP_213956.1 15606576 1192922 984638..985018 1 NC_000918.1 NADH dehydrogenase I subunit A 985018 nuoA1 1192922 nuoA1 Aquifex aeolicus VF5 NADH dehydrogenase I subunit A NP_213956.1 984638 D 224324 CDS NP_213957.1 15606577 1192923 984987..985766 1 NC_000918.1 hypothetical protein 985766 1192923 aq_1386 Aquifex aeolicus VF5 hypothetical protein NP_213957.1 984987 D 224324 CDS NP_213958.1 15606578 1192924 985792..986100 1 NC_000918.1 ArsR family transcriptional regulator 986100 arsR 1192924 arsR Aquifex aeolicus VF5 ArsR family transcriptional regulator NP_213958.1 985792 D 224324 CDS NP_213959.1 15606579 1192925 986343..987302 1 NC_000918.1 hypothetical protein 987302 1192925 aq_1388 Aquifex aeolicus VF5 hypothetical protein NP_213959.1 986343 D 224324 CDS NP_213960.1 15606580 1192926 complement(987292..988224) 1 NC_000918.1 fructose-1,6-bisphosphate aldolase class II 988224 fba 1192926 fba Aquifex aeolicus VF5 fructose-1,6-bisphosphate aldolase class II NP_213960.1 987292 R 224324 CDS NP_213961.1 15606581 1192927 988669..989634 1 NC_000918.1 hypothetical protein 989634 1192927 aq_1391 Aquifex aeolicus VF5 hypothetical protein NP_213961.1 988669 D 224324 CDS NP_213962.1 15606582 1192928 989839..990717 1 NC_000918.1 hypothetical protein 990717 1192928 aq_1392 Aquifex aeolicus VF5 hypothetical protein NP_213962.1 989839 D 224324 CDS NP_213963.1 15606583 1192929 complement(990701..992458) 1 NC_000918.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase 992458 lig 1192929 lig Aquifex aeolicus VF5 ATP-dependent DNA ligase NP_213963.1 990701 R 224324 CDS NP_213964.2 566344045 1192930 complement(992455..992955) 1 NC_000918.1 3-isopropylmalate dehydratase 992955 leuD 1192930 leuD Aquifex aeolicus VF5 3-isopropylmalate dehydratase NP_213964.2 992455 R 224324 CDS NP_213965.1 15606585 1192931 993552..995600 1 NC_000918.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 995600 1192931 aq_1400 Aquifex aeolicus VF5 cellulose synthase regulator protein NP_213965.1 993552 D 224324 CDS NP_213966.1 15606586 1192932 995597..996574 1 NC_000918.1 endoglucanase fragment 996574 celY 1192932 celY Aquifex aeolicus VF5 endoglucanase fragment NP_213966.1 995597 D 224324 CDS NP_213967.1 15606587 1192933 996504..998516 1 NC_000918.1 hypothetical protein 998516 1192933 aq_1402 Aquifex aeolicus VF5 hypothetical protein NP_213967.1 996504 D 224324 CDS NP_213968.1 15606588 1192934 998504..999496 1 NC_000918.1 hypothetical protein 999496 1192934 aq_1403 Aquifex aeolicus VF5 hypothetical protein NP_213968.1 998504 D 224324 CDS NP_213969.1 15606589 1192935 999493..1000227 1 NC_000918.1 hypothetical protein 1000227 1192935 aq_1404 Aquifex aeolicus VF5 hypothetical protein NP_213969.1 999493 D 224324 CDS NP_213970.1 15606590 1192936 complement(1000217..1000894) 1 NC_000918.1 hypothetical protein 1000894 1192936 aq_1405 Aquifex aeolicus VF5 hypothetical protein NP_213970.1 1000217 R 224324 CDS NP_213971.1 15606591 1192937 complement(1000870..1003149) 1 NC_000918.1 cellulose synthase catalytic subunit 1003149 bcsA 1192937 bcsA Aquifex aeolicus VF5 cellulose synthase catalytic subunit NP_213971.1 1000870 R 224324 CDS NP_213972.1 15606592 1192938 1003352..1004191 1 NC_000918.1 hypothetical protein 1004191 1192938 aq_1408 Aquifex aeolicus VF5 hypothetical protein NP_213972.1 1003352 D 224324 CDS NP_213973.1 15606593 1192939 1004130..1004525 1 NC_000918.1 hypothetical protein 1004525 1192939 aq_1409 Aquifex aeolicus VF5 hypothetical protein NP_213973.1 1004130 D 224324 CDS NP_213974.1 15606594 1192940 complement(1004522..1005826) 1 NC_000918.1 catalyzes the formation of L-tryptophan from indole and L-serine; tryptophan synthase subunit beta 1005826 trpB2 1192940 trpB2 Aquifex aeolicus VF5 tryptophan synthase subunit beta NP_213974.1 1004522 R 224324 CDS NP_213975.1 15606595 1192941 complement(1005831..1006916) 1 NC_000918.1 hypothetical protein 1006916 1192941 aq_1412 Aquifex aeolicus VF5 hypothetical protein NP_213975.1 1005831 R 224324 CDS NP_213976.1 15606596 1192942 1006934..1010431 1 NC_000918.1 valyl-tRNA synthetase 1010431 valS 1192942 valS Aquifex aeolicus VF5 valyl-tRNA synthetase NP_213976.1 1006934 D 224324 CDS NP_213977.1 15606597 1192943 complement(1010435..1010893) 1 NC_000918.1 FUR family transcriptional regulator 1010893 furR2 1192943 furR2 Aquifex aeolicus VF5 FUR family transcriptional regulator NP_213977.1 1010435 R 224324 CDS NP_213978.1 15606598 1192944 complement(1010900..1011505) 1 NC_000918.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 1011505 mobA 1192944 mobA Aquifex aeolicus VF5 molybdopterin-guanine dinucleotide biosynthesis protein MobA NP_213978.1 1010900 R 224324 CDS NP_213979.1 15606599 1192945 complement(1011429..1012328) 1 NC_000918.1 hypothetical protein 1012328 1192945 aq_1420 Aquifex aeolicus VF5 hypothetical protein NP_213979.1 1011429 R 224324 CDS NP_213980.1 15606600 1192946 1012351..1012944 1 NC_000918.1 hypothetical protein 1012944 1192946 aq_1421 Aquifex aeolicus VF5 hypothetical protein NP_213980.1 1012351 D 224324 CDS NP_213981.1 15606601 1192947 complement(1012941..1014686) 1 NC_000918.1 DNA polymerase beta family protein 1014686 dpbF 1192947 dpbF Aquifex aeolicus VF5 DNA polymerase beta family protein NP_213981.1 1012941 R 224324 CDS NP_213982.1 15606602 1192948 1014723..1015451 1 NC_000918.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1015451 pdxJ 1192948 pdxJ Aquifex aeolicus VF5 pyridoxine 5'-phosphate synthase NP_213982.1 1014723 D 224324 CDS NP_213983.1 15606603 1192949 complement(1015431..1016543) 1 NC_000918.1 oxygen-independent coproporphyrinogen III oxidase 1016543 hemF 1192949 hemF Aquifex aeolicus VF5 oxygen-independent coproporphyrinogen III oxidase NP_213983.1 1015431 R 224324 CDS NP_213984.1 15606604 1192950 1016582..1016884 1 NC_000918.1 hypothetical protein 1016884 1192950 aq_1426 Aquifex aeolicus VF5 hypothetical protein NP_213984.1 1016582 D 224324 CDS NP_213985.1 15606605 1192951 1016881..1017951 1 NC_000918.1 lipid A disaccharide synthetase 1017951 lpxB 1192951 lpxB Aquifex aeolicus VF5 lipid A disaccharide synthetase NP_213985.1 1016881 D 224324 CDS NP_213986.1 15606606 1192952 1017961..1018590 1 NC_000918.1 hypothetical protein 1018590 1192952 aq_1428 Aquifex aeolicus VF5 hypothetical protein NP_213986.1 1017961 D 224324 CDS NP_213987.1 15606607 1192953 complement(1018582..1019472) 1 NC_000918.1 5,10-methylenetetrahydrofolate reductase 1019472 metF 1192953 metF Aquifex aeolicus VF5 5,10-methylenetetrahydrofolate reductase NP_213987.1 1018582 R 224324 CDS NP_213988.1 15606608 1192954 1019553..1019915 1 NC_000918.1 pilin 1019915 ppdD1 1192954 ppdD1 Aquifex aeolicus VF5 pilin NP_213988.1 1019553 D 224324 CDS NP_213989.1 15606609 1192955 1019985..1020344 1 NC_000918.1 minor pilin 1020344 fimZ 1192955 fimZ Aquifex aeolicus VF5 minor pilin NP_213989.1 1019985 D 224324 CDS NP_213990.1 15606610 1192956 1020328..1020765 1 NC_000918.1 pilin 1020765 ppdD2 1192956 ppdD2 Aquifex aeolicus VF5 pilin NP_213990.1 1020328 D 224324 CDS NP_213991.1 15606611 1192957 1020672..1021103 1 NC_000918.1 pilin 1021103 ppdD3 1192957 ppdD3 Aquifex aeolicus VF5 pilin NP_213991.1 1020672 D 224324 CDS NP_213992.1 15606612 1192958 1021100..1021930 1 NC_000918.1 hypothetical protein 1021930 1192958 aq_1436 Aquifex aeolicus VF5 hypothetical protein NP_213992.1 1021100 D 224324 CDS NP_213993.1 15606613 1192959 1021935..1023788 1 NC_000918.1 hypothetical protein 1023788 1192959 aq_1439 Aquifex aeolicus VF5 hypothetical protein NP_213993.1 1021935 D 224324 CDS NP_213994.1 15606614 1192960 1023795..1025549 1 NC_000918.1 extracellular solute binding protein 1025549 oppA 1192960 oppA Aquifex aeolicus VF5 extracellular solute binding protein NP_213994.1 1023795 D 224324 CDS NP_213995.1 15606615 1192961 1025935..1029099 1 NC_000918.1 hypothetical protein 1029099 1192961 aq_1442 Aquifex aeolicus VF5 hypothetical protein NP_213995.1 1025935 D 224324 CDS NP_213996.1 15606616 1192962 complement(1029091..1029678) 1 NC_000918.1 hypothetical protein 1029678 1192962 aq_1444 Aquifex aeolicus VF5 hypothetical protein NP_213996.1 1029091 R 224324 CDS NP_213997.1 15606617 1192963 complement(1029714..1031753) 1 NC_000918.1 cation transporter E1-E2 family ATPase 1031753 ctrA2 1192963 ctrA2 Aquifex aeolicus VF5 cation transporter E1-E2 family ATPase NP_213997.1 1029714 R 224324 CDS NP_213998.1 15606618 1192964 complement(1031810..1032367) 1 NC_000918.1 hypothetical protein 1032367 1192964 aq_1446 Aquifex aeolicus VF5 hypothetical protein NP_213998.1 1031810 R 224324 CDS NP_213999.1 15606619 1192965 complement(1032379..1034499) 1 NC_000918.1 hypothetical protein 1034499 1192965 aq_1447 Aquifex aeolicus VF5 hypothetical protein NP_213999.1 1032379 R 224324 CDS NP_214000.1 15606620 1192966 complement(1034504..1034923) 1 NC_000918.1 8-oxo-dGTPase domain-containing protein 1034923 mutT 1192966 mutT Aquifex aeolicus VF5 8-oxo-dGTPase domain-containing protein NP_214000.1 1034504 R 224324 CDS NP_214001.1 15606621 1192967 1034952..1036313 1 NC_000918.1 periplasmic serine protease 1036313 htrA 1192967 htrA Aquifex aeolicus VF5 periplasmic serine protease NP_214001.1 1034952 D 224324 CDS NP_214002.1 15606622 1192968 1036324..1037256 1 NC_000918.1 RNA polymerase sigma factor RpoS 1037256 rpoS 1192968 rpoS Aquifex aeolicus VF5 RNA polymerase sigma factor RpoS NP_214002.1 1036324 D 224324 CDS NP_214003.1 15606623 1192969 1037256..1038068 1 NC_000918.1 hypothetical protein 1038068 1192969 aq_1453 Aquifex aeolicus VF5 hypothetical protein NP_214003.1 1037256 D 224324 CDS NP_214004.1 15606624 1192970 1038417..1039127 1 NC_000918.1 hypothetical protein 1039127 1192970 aq_1455 Aquifex aeolicus VF5 hypothetical protein NP_214004.1 1038417 D 224324 CDS NP_214005.1 15606625 1192971 complement(1038984..1039616) 1 NC_000918.1 hypothetical protein 1039616 1192971 aq_1457 Aquifex aeolicus VF5 hypothetical protein NP_214005.1 1038984 R 224324 CDS NP_214007.1 15606627 1192973 complement(1040657..1042405) 1 NC_000918.1 neutral protease 1042405 npr 1192973 npr Aquifex aeolicus VF5 neutral protease NP_214007.1 1040657 R 224324 CDS NP_214008.1 15606628 1192974 1042119..1043009 1 NC_000918.1 hypothetical protein 1043009 1192974 aq_1462 Aquifex aeolicus VF5 hypothetical protein NP_214008.1 1042119 D 224324 CDS NP_214009.1 15606629 1192975 1043006..1043755 1 NC_000918.1 hypothetical protein 1043755 1192975 aq_1464 Aquifex aeolicus VF5 hypothetical protein NP_214009.1 1043006 D 224324 CDS NP_214010.1 15606630 1192976 1043752..1044144 1 NC_000918.1 hypothetical protein 1044144 1192976 aq_1465 Aquifex aeolicus VF5 hypothetical protein NP_214010.1 1043752 D 224324 CDS NP_214011.1 15606631 1192977 complement(1044125..1044505) 1 NC_000918.1 hypothetical protein 1044505 1192977 aq_1466 Aquifex aeolicus VF5 hypothetical protein NP_214011.1 1044125 R 224324 CDS NP_214012.1 15606632 1192978 complement(1044483..1045253) 1 NC_000918.1 hypothetical protein 1045253 1192978 aq_1467 Aquifex aeolicus VF5 hypothetical protein NP_214012.1 1044483 R 224324 CDS NP_214013.1 15606633 1192979 complement(1045240..1046439) 1 NC_000918.1 dihydropteroate synthase 1046439 folP 1192979 folP Aquifex aeolicus VF5 dihydropteroate synthase NP_214013.1 1045240 R 224324 CDS YP_008920732.1 566344052 17925351 complement(1046464..1046673) 1 NC_000918.1 hypothetical protein 1046673 17925351 aq_1468a Aquifex aeolicus VF5 hypothetical protein YP_008920732.1 1046464 R 224324 CDS NP_214014.1 15606634 1192980 1047198..1048631 1 NC_000918.1 biotin carboxylase 1048631 accC2 1192980 accC2 Aquifex aeolicus VF5 biotin carboxylase NP_214014.1 1047198 D 224324 CDS NP_214015.1 15606635 1192981 1049037..1050443 1 NC_000918.1 replicative DNA helicase 1050443 dnaB 1192981 dnaB Aquifex aeolicus VF5 replicative DNA helicase NP_214015.1 1049037 D 224324 CDS NP_214016.1 15606636 1192982 1050573..1051361 1 NC_000918.1 hypothetical protein 1051361 1192982 aq_1473 Aquifex aeolicus VF5 hypothetical protein NP_214016.1 1050573 D 224324 CDS NP_214017.1 15606637 1192983 1051345..1052754 1 NC_000918.1 general secretion pathway protein E 1052754 gspE 1192983 gspE Aquifex aeolicus VF5 general secretion pathway protein E NP_214017.1 1051345 D 224324 CDS NP_214018.1 15606638 1192984 1052751..1053293 1 NC_000918.1 hypothetical protein 1053293 1192984 aq_1476 Aquifex aeolicus VF5 hypothetical protein NP_214018.1 1052751 D 224324 CDS NP_214019.1 15606639 1192985 1053274..1054095 1 NC_000918.1 hypothetical protein 1054095 1192985 aq_1477 Aquifex aeolicus VF5 hypothetical protein NP_214019.1 1053274 D 224324 CDS NP_214020.1 15606640 1192986 complement(1054026..1054661) 1 NC_000918.1 recombination protein RecR 1054661 recR 1192986 recR Aquifex aeolicus VF5 recombination protein RecR NP_214020.1 1054026 R 224324 CDS NP_214021.1 15606641 1192987 complement(1054920..1055510) 1 NC_000918.1 hypothetical protein 1055510 1192987 aq_1480 Aquifex aeolicus VF5 hypothetical protein NP_214021.1 1054920 R 224324 CDS NP_214022.1 15606642 1192988 complement(1055518..1056003) 1 NC_000918.1 hypothetical protein 1056003 1192988 aq_1481 Aquifex aeolicus VF5 hypothetical protein NP_214022.1 1055518 R 224324 CDS NP_214023.1 15606643 1192989 complement(1056000..1056485) 1 NC_000918.1 hypothetical protein 1056485 1192989 aq_1482 Aquifex aeolicus VF5 hypothetical protein NP_214023.1 1056000 R 224324 CDS NP_214024.1 15606644 1192990 complement(1056478..1057104) 1 NC_000918.1 hypothetical protein 1057104 1192990 aq_1483 Aquifex aeolicus VF5 hypothetical protein NP_214024.1 1056478 R 224324 CDS NP_214025.1 15606645 1192991 complement(1057089..1057619) 1 NC_000918.1 hypothetical protein 1057619 1192991 aq_1484 Aquifex aeolicus VF5 hypothetical protein NP_214025.1 1057089 R 224324 CDS NP_214026.1 15606646 1192992 complement(1057616..1057900) 1 NC_000918.1 DNA binding protein HU 1057900 himA 1192992 himA Aquifex aeolicus VF5 DNA binding protein HU NP_214026.1 1057616 R 224324 CDS NP_214027.1 15606647 1192993 complement(1057932..1059539) 1 NC_000918.1 ribosomal protein S01 1059539 rpsA 1192993 rpsA Aquifex aeolicus VF5 ribosomal protein S01 NP_214027.1 1057932 R 224324 CDS NP_214028.1 15606648 1192994 complement(1059606..1060379) 1 NC_000918.1 tRNA guanine-N1 methyltransferase 1060379 trmD 1192994 trmD Aquifex aeolicus VF5 tRNA guanine-N1 methyltransferase NP_214028.1 1059606 R 224324 CDS NP_214029.1 15606649 1192995 complement(1060369..1062096) 1 NC_000918.1 RNA polymerase sigma factor RpoD 1062096 rpoD 1192995 rpoD Aquifex aeolicus VF5 RNA polymerase sigma factor RpoD NP_214029.1 1060369 R 224324 CDS NP_214030.1 15606650 1192996 complement(1062135..1063631) 1 NC_000918.1 DNA primase 1063631 dnaG 1192996 dnaG Aquifex aeolicus VF5 DNA primase NP_214030.1 1062135 R 224324 CDS NP_214031.1 15606651 1192997 1063698..1064084 1 NC_000918.1 hypothetical protein 1064084 1192997 aq_1494 Aquifex aeolicus VF5 hypothetical protein NP_214031.1 1063698 D 224324 CDS NP_214032.2 566344044 1192998 complement(1064073..1064540) 1 NC_000918.1 O-6-methylguanine-DNA-alkyltransferase 1064540 ogt 1192998 ogt Aquifex aeolicus VF5 O-6-methylguanine-DNA-alkyltransferase NP_214032.2 1064073 R 224324 CDS NP_214033.1 15606653 1192999 complement(1064736..1065596) 1 NC_000918.1 NagC/XylR family transcriptional regulator 1065596 xylR 1192999 xylR Aquifex aeolicus VF5 NagC/XylR family transcriptional regulator NP_214033.1 1064736 R 224324 CDS NP_214034.1 15606654 1193000 complement(1065593..1065988) 1 NC_000918.1 hypothetical protein 1065988 1193000 aq_1498 Aquifex aeolicus VF5 hypothetical protein NP_214034.1 1065593 R 224324 CDS NP_214035.1 15606655 1193001 1066291..1066932 1 NC_000918.1 Fe/Mn family superoxide dismutase 1066932 sodA 1193001 sodA Aquifex aeolicus VF5 Fe/Mn family superoxide dismutase NP_214035.1 1066291 D 224324 CDS NP_214036.1 15606656 1193094 1066938..1067708 1 NC_000918.1 hypothetical protein 1067708 1193094 aq_1501 Aquifex aeolicus VF5 hypothetical protein NP_214036.1 1066938 D 224324 CDS NP_214037.1 15606657 1193095 complement(1067668..1068834) 1 NC_000918.1 hypothetical protein 1068834 1193095 aq_1502 Aquifex aeolicus VF5 hypothetical protein NP_214037.1 1067668 R 224324 CDS NP_214038.1 15606658 1193096 complement(1068818..1069474) 1 NC_000918.1 hypothetical protein 1069474 1193096 aq_1503 Aquifex aeolicus VF5 hypothetical protein NP_214038.1 1068818 R 224324 CDS NP_214039.1 15606659 1193097 complement(1069471..1070802) 1 NC_000918.1 K+ transport protein 1070802 trk1 1193097 trk1 Aquifex aeolicus VF5 K+ transport protein NP_214039.1 1069471 R 224324 CDS NP_214040.1 15606660 1193098 complement(1070796..1072886) 1 NC_000918.1 ribonucleotide reductase subunit beta 1072886 nrdF 1193098 nrdF Aquifex aeolicus VF5 ribonucleotide reductase subunit beta NP_214040.1 1070796 R 224324 CDS NP_214041.1 15606661 1193099 complement(1072992..1073630) 1 NC_000918.1 O-methyltransferase 1073630 omt 1193099 omt Aquifex aeolicus VF5 O-methyltransferase NP_214041.1 1072992 R 224324 CDS NP_214042.1 15606662 1193100 complement(1073611..1074489) 1 NC_000918.1 hypothetical protein 1074489 1193100 aq_1508 Aquifex aeolicus VF5 hypothetical protein NP_214042.1 1073611 R 224324 CDS NP_214043.1 15606663 1193101 complement(1074470..1075465) 1 NC_000918.1 oligopeptide transport system permease 1075465 oppC 1193101 oppC Aquifex aeolicus VF5 oligopeptide transport system permease NP_214043.1 1074470 R 224324 CDS NP_214044.1 15606664 1193102 complement(1075465..1076124) 1 NC_000918.1 hypothetical protein 1076124 1193102 aq_1510 Aquifex aeolicus VF5 hypothetical protein NP_214044.1 1075465 R 224324 CDS NP_214045.1 15606665 1193103 1076238..1077518 1 NC_000918.1 isocitrate dehydrogenase 1077518 icd 1193103 icd Aquifex aeolicus VF5 isocitrate dehydrogenase NP_214045.1 1076238 D 224324 CDS NP_214046.1 15606666 1193104 1077544..1077960 1 NC_000918.1 hypothetical protein 1077960 1193104 aq_1515 Aquifex aeolicus VF5 hypothetical protein NP_214046.1 1077544 D 224324 CDS NP_214047.1 15606667 1193105 1078019..1078513 1 NC_000918.1 hypothetical protein 1078513 1193105 aq_1516 Aquifex aeolicus VF5 hypothetical protein NP_214047.1 1078019 D 224324 CDS NP_214048.1 15606668 1193106 1078513..1079931 1 NC_000918.1 pyruvate carboxylase N-terminal domain-containing protein 1079931 pycB 1193106 pycB Aquifex aeolicus VF5 pyruvate carboxylase N-terminal domain-containing protein NP_214048.1 1078513 D 224324 CDS NP_214049.1 15606669 1193107 1079955..1081922 1 NC_000918.1 catalyzes the formation of oxaloacetate from pyruvate; pyruvate carboxylase subunit B 1081922 pycA 1193107 pycA Aquifex aeolicus VF5 pyruvate carboxylase subunit B NP_214049.1 1079955 D 224324 CDS NP_214050.1 15606670 1193108 1081963..1082547 1 NC_000918.1 hypothetical protein 1082547 1193108 aq_1525 Aquifex aeolicus VF5 hypothetical protein NP_214050.1 1081963 D 224324 CDS NP_214051.1 15606671 1193109 1082598..1083515 1 NC_000918.1 hypothetical protein 1083515 1193109 aq_1526 Aquifex aeolicus VF5 hypothetical protein NP_214051.1 1082598 D 224324 CDS NP_214052.1 15606672 1193110 1083586..1084476 1 NC_000918.1 hypothetical protein 1084476 1193110 aq_1527 Aquifex aeolicus VF5 hypothetical protein NP_214052.1 1083586 D 224324 CDS NP_214053.1 15606673 1193111 1084448..1085260 1 NC_000918.1 hypothetical protein 1085260 1193111 aq_1528 Aquifex aeolicus VF5 hypothetical protein NP_214053.1 1084448 D 224324 CDS NP_214054.1 15606674 1193112 1085257..1086279 1 NC_000918.1 hypothetical protein 1086279 1193112 aq_1530 Aquifex aeolicus VF5 hypothetical protein NP_214054.1 1085257 D 224324 CDS NP_214055.1 15606675 1193113 1086276..1087019 1 NC_000918.1 ABC transporter 1087019 abcT10 1193113 abcT10 Aquifex aeolicus VF5 ABC transporter NP_214055.1 1086276 D 224324 CDS NP_214056.1 15606676 1193114 1087007..1087909 1 NC_000918.1 hypothetical protein 1087909 1193114 aq_1533 Aquifex aeolicus VF5 hypothetical protein NP_214056.1 1087007 D 224324 CDS NP_214057.1 15606677 1193115 1087903..1088415 1 NC_000918.1 hypothetical protein 1088415 1193115 aq_1534 Aquifex aeolicus VF5 hypothetical protein NP_214057.1 1087903 D 224324 CDS NP_214058.1 15606678 1193116 complement(1088358..1089422) 1 NC_000918.1 xaa-pro dipeptidase 1089422 pepQ 1193116 pepQ Aquifex aeolicus VF5 xaa-pro dipeptidase NP_214058.1 1088358 R 224324 CDS NP_214059.1 15606679 1193117 complement(1089424..1090719) 1 NC_000918.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1090719 aroA 1193117 aroA Aquifex aeolicus VF5 3-phosphoshikimate 1-carboxyvinyltransferase NP_214059.1 1089424 R 224324 CDS NP_214060.1 15606680 1193118 complement(1090757..1091095) 1 NC_000918.1 flagellar switch protein FliN 1091095 fliN 1193118 fliN Aquifex aeolicus VF5 flagellar switch protein FliN NP_214060.1 1090757 R 224324 CDS NP_214061.1 15606681 1193119 complement(1091079..1092152) 1 NC_000918.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1092152 ispG 1193119 ispG Aquifex aeolicus VF5 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NP_214061.1 1091079 R 224324 CDS NP_214062.1 15606682 1193120 1092168..1092740 1 NC_000918.1 hypothetical protein 1092740 1193120 aq_1542 Aquifex aeolicus VF5 hypothetical protein NP_214062.1 1092168 D 224324 CDS NP_214063.1 15606683 1193121 1092737..1093675 1 NC_000918.1 ADP-heptose--LPS heptosyltransferase 1093675 rfaC1 1193121 rfaC1 Aquifex aeolicus VF5 ADP-heptose--LPS heptosyltransferase NP_214063.1 1092737 D 224324 CDS NP_214064.1 15606684 1193122 1093706..1095139 1 NC_000918.1 hypothetical protein 1095139 1193122 aq_1545 Aquifex aeolicus VF5 hypothetical protein NP_214064.1 1093706 D 224324 CDS NP_214065.1 15606685 1193123 complement(1095136..1096104) 1 NC_000918.1 polysialic acid capsule expression protein 1096104 kpsF 1193123 kpsF Aquifex aeolicus VF5 polysialic acid capsule expression protein NP_214065.1 1095136 R 224324 CDS NP_214066.1 15606686 1193124 complement(1096105..1096641) 1 NC_000918.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 1096641 ppa 1193124 ppa Aquifex aeolicus VF5 inorganic pyrophosphatase NP_214066.1 1096105 R 224324 CDS NP_214067.1 15606687 1193125 complement(1096848..1097636) 1 NC_000918.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1097636 trpA 1193125 trpA Aquifex aeolicus VF5 tryptophan synthase subunit alpha NP_214067.1 1096848 R 224324 CDS NP_214068.1 15606688 1193126 complement(1097624..1098022) 1 NC_000918.1 hypothetical protein 1098022 1193126 aq_1549 Aquifex aeolicus VF5 hypothetical protein NP_214068.1 1097624 R 224324 CDS NP_214069.1 15606689 1193127 complement(1098061..1098375) 1 NC_000918.1 cytochrome C552 1098375 cycB2 1193127 cycB2 Aquifex aeolicus VF5 cytochrome C552 NP_214069.1 1098061 R 224324 CDS NP_214070.1 15606690 1193128 complement(1098424..1099281) 1 NC_000918.1 enoyl-ACP reductase 1099281 fabI 1193128 fabI Aquifex aeolicus VF5 enoyl-ACP reductase NP_214070.1 1098424 R 224324 CDS NP_214071.1 15606691 1193129 complement(1099250..1100044) 1 NC_000918.1 catalyzes the reversible formation of fructose 1,6-bisphosphate from glycerone phosphate and D-glyceraldehyde 3-phosphate; fructose-bisphosphate aldolase 1100044 1193129 aq_1554 Aquifex aeolicus VF5 fructose-bisphosphate aldolase NP_214071.1 1099250 R 224324 CDS NP_214072.1 15606692 1193130 1100086..1101069 1 NC_000918.1 cysteine synthase, O-acetylserine (thiol) lyase B 1101069 cysM 1193130 cysM Aquifex aeolicus VF5 cysteine synthase, O-acetylserine (thiol) lyase B NP_214072.1 1100086 D 224324 CDS NP_214073.1 15606693 1193131 1101097..1102194 1 NC_000918.1 hypothetical protein 1102194 1193131 aq_1558 Aquifex aeolicus VF5 hypothetical protein NP_214073.1 1101097 D 224324 CDS NP_214074.1 15606694 1193132 1102175..1102747 1 NC_000918.1 gliding motility protein 1102747 mglA1 1193132 mglA1 Aquifex aeolicus VF5 gliding motility protein NP_214074.1 1102175 D 224324 CDS NP_214075.1 15606695 1193133 1102744..1104126 1 NC_000918.1 hypothetical protein 1104126 1193133 aq_1562 Aquifex aeolicus VF5 hypothetical protein NP_214075.1 1102744 D 224324 CDS NP_214076.1 15606696 1193134 1104123..1105787 1 NC_000918.1 ABC transporter 1105787 abcT13 1193134 abcT13 Aquifex aeolicus VF5 ABC transporter NP_214076.1 1104123 D 224324 CDS NP_214077.1 15606697 1193135 1105818..1110299 1 NC_000918.1 glutamate synthase 1110299 gltB 1193135 gltB Aquifex aeolicus VF5 glutamate synthase NP_214077.1 1105818 D 224324 CDS NP_214078.1 15606698 1193136 1110269..1111405 1 NC_000918.1 hypothetical protein 1111405 1193136 aq_1569 Aquifex aeolicus VF5 hypothetical protein NP_214078.1 1110269 D 224324 CDS NP_214079.1 15606699 1193137 1111294..1111680 1 NC_000918.1 hypothetical protein 1111680 1193137 aq_1570 Aquifex aeolicus VF5 hypothetical protein NP_214079.1 1111294 D 224324 CDS NP_214080.1 15606700 1193138 1111685..1112365 1 NC_000918.1 hypothetical protein 1112365 1193138 aq_1571 Aquifex aeolicus VF5 hypothetical protein NP_214080.1 1111685 D 224324 CDS NP_214081.1 15606701 1193139 complement(1112362..1112805) 1 NC_000918.1 hypothetical protein 1112805 1193139 aq_1574 Aquifex aeolicus VF5 hypothetical protein NP_214081.1 1112362 R 224324 CDS NP_214082.1 15606702 1193140 1112819..1113568 1 NC_000918.1 hypothetical protein 1113568 1193140 aq_1575 Aquifex aeolicus VF5 hypothetical protein NP_214082.1 1112819 D 224324 CDS NP_214083.1 15606703 1193141 1113601..1114878 1 NC_000918.1 DNA mismatch repair protein MutL 1114878 mutL 1193141 mutL Aquifex aeolicus VF5 DNA mismatch repair protein MutL NP_214083.1 1113601 D 224324 CDS NP_214084.1 15606704 1193142 1114896..1115450 1 NC_000918.1 invasion protein IagB 1115450 iagB 1193142 iagB Aquifex aeolicus VF5 invasion protein IagB NP_214084.1 1114896 D 224324 CDS NP_214085.1 15606705 1193143 1115453..1116148 1 NC_000918.1 orotidine-5'-phosphate decarboxylase 1116148 pyrF 1193143 pyrF Aquifex aeolicus VF5 orotidine-5'-phosphate decarboxylase NP_214085.1 1115453 D 224324 CDS NP_214086.1 15606706 1193144 1116145..1116648 1 NC_000918.1 hypothetical protein 1116648 1193144 aq_1581 Aquifex aeolicus VF5 hypothetical protein NP_214086.1 1116145 D 224324 CDS NP_214087.1 15606707 1193145 1116629..1117219 1 NC_000918.1 glucose inhibited division protein B 1117219 gidB 1193145 gidB Aquifex aeolicus VF5 glucose inhibited division protein B NP_214087.1 1116629 D 224324 CDS NP_214088.1 15606708 1193146 1117204..1117893 1 NC_000918.1 hypothetical protein 1117893 1193146 aq_1583 Aquifex aeolicus VF5 hypothetical protein NP_214088.1 1117204 D 224324 CDS NP_214089.1 15606709 1193147 1117890..1119074 1 NC_000918.1 hypothetical protein 1119074 1193147 aq_1585 Aquifex aeolicus VF5 hypothetical protein NP_214089.1 1117890 D 224324 CDS NP_214090.1 15606710 1193148 1119108..1119542 1 NC_000918.1 ATP synthase F0 subunit b 1119542 atpF1 1193148 atpF1 Aquifex aeolicus VF5 ATP synthase F0 subunit b NP_214090.1 1119108 D 224324 CDS NP_214091.1 15606711 1193149 1119542..1120099 1 NC_000918.1 ATP synthase F0 subunit b 1120099 atpF2 1193149 atpF2 Aquifex aeolicus VF5 ATP synthase F0 subunit b NP_214091.1 1119542 D 224324 CDS NP_214092.1 15606712 1193150 1120092..1120637 1 NC_000918.1 ATP synthase F1 subunit delta 1120637 atpH 1193150 atpH Aquifex aeolicus VF5 ATP synthase F1 subunit delta NP_214092.1 1120092 D 224324 CDS NP_214093.1 15606713 1193151 1120638..1121066 1 NC_000918.1 nucleoside diphosphate kinase 1121066 ndk 1193151 ndk Aquifex aeolicus VF5 nucleoside diphosphate kinase NP_214093.1 1120638 D 224324 CDS NP_214096.1 15606716 1193154 complement(1122505..1123836) 1 NC_000918.1 flagellar export protein 1123836 fliI 1193154 fliI Aquifex aeolicus VF5 flagellar export protein NP_214096.1 1122505 R 224324 CDS NP_214097.1 15606717 1193155 complement(1123763..1124446) 1 NC_000918.1 hypothetical protein 1124446 1193155 aq_1596 Aquifex aeolicus VF5 hypothetical protein NP_214097.1 1123763 R 224324 CDS NP_214098.1 15606718 1193156 1124683..1125633 1 NC_000918.1 hypothetical protein 1125633 1193156 aq_1598 Aquifex aeolicus VF5 hypothetical protein NP_214098.1 1124683 D 224324 CDS NP_214099.1 15606719 1193157 complement(1125619..1126095) 1 NC_000918.1 hypothetical protein 1126095 1193157 aq_1599 Aquifex aeolicus VF5 hypothetical protein NP_214099.1 1125619 R 224324 CDS NP_214100.1 15606720 1193158 complement(1126123..1126887) 1 NC_000918.1 type 4 prepilin peptidase 1126887 pilD 1193158 pilD Aquifex aeolicus VF5 type 4 prepilin peptidase NP_214100.1 1126123 R 224324 CDS NP_214101.1 15606721 1193159 complement(1126884..1127750) 1 NC_000918.1 protein-export membrane protein 1127750 secF 1193159 secF Aquifex aeolicus VF5 protein-export membrane protein NP_214101.1 1126884 R 224324 CDS NP_214102.1 15606722 1193160 complement(1127747..1128403) 1 NC_000918.1 hypothetical protein 1128403 1193160 aq_1603 Aquifex aeolicus VF5 hypothetical protein NP_214102.1 1127747 R 224324 CDS NP_214103.1 15606723 1193161 complement(1129090..1129827) 1 NC_000918.1 aminodeoxychorismate lyase 1129827 pabC 1193161 pabC Aquifex aeolicus VF5 aminodeoxychorismate lyase NP_214103.1 1129090 R 224324 CDS NP_214104.1 15606724 1193162 complement(1129820..1130362) 1 NC_000918.1 deoxycytidine triphosphate deaminase 1130362 dcd 1193162 dcd Aquifex aeolicus VF5 deoxycytidine triphosphate deaminase NP_214104.1 1129820 R 224324 CDS NP_214105.1 15606725 1193163 complement(1130689..1131411) 1 NC_000918.1 molybdate periplasmic binding protein 1131411 modA 1193163 modA Aquifex aeolicus VF5 molybdate periplasmic binding protein NP_214105.1 1130689 R 224324 CDS NP_214106.1 15606726 1193164 complement(1131408..1132103) 1 NC_000918.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1132103 radC 1193164 radC Aquifex aeolicus VF5 DNA repair protein RadC NP_214106.1 1131408 R 224324 CDS NP_214107.1 15606727 1193165 complement(1132079..1133539) 1 NC_000918.1 hypothetical protein 1133539 1193165 aq_1612 Aquifex aeolicus VF5 hypothetical protein NP_214107.1 1132079 R 224324 CDS NP_214108.1 15606728 1193166 complement(1133511..1134155) 1 NC_000918.1 ATP phosphoribosyltransferase 1134155 hisG 1193166 hisG Aquifex aeolicus VF5 ATP phosphoribosyltransferase NP_214108.1 1133511 R 224324 CDS NP_214109.1 15606729 1193167 complement(1134152..1136014) 1 NC_000918.1 catalyzes the formation of oxaloacetate from pyruvate; pyruvate carboxylase subunit B 1136014 oadA 1193167 oadA Aquifex aeolicus VF5 pyruvate carboxylase subunit B NP_214109.1 1134152 R 224324 CDS NP_214110.1 15606730 1193168 1136058..1137299 1 NC_000918.1 hypothetical protein 1137299 1193168 aq_1618 Aquifex aeolicus VF5 hypothetical protein NP_214110.1 1136058 D 224324 CDS NP_214111.1 15606731 1193169 1137329..1138486 1 NC_000918.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1138486 sucC 1193169 sucC Aquifex aeolicus VF5 succinyl-CoA synthetase subunit beta NP_214111.1 1137329 D 224324 CDS NP_214112.1 15606732 1193170 1138498..1139415 1 NC_000918.1 succinyl-CoA ligase subunit alpha 1139415 sucD2 1193170 sucD2 Aquifex aeolicus VF5 succinyl-CoA ligase subunit alpha NP_214112.1 1138498 D 224324 CDS YP_008920733.1 566344053 17925352 1139479..1139709 1 NC_000918.1 hypothetical protein 1139709 17925352 aq_1622a Aquifex aeolicus VF5 hypothetical protein YP_008920733.1 1139479 D 224324 CDS NP_214113.1 15606733 1193171 1140007..1140756 1 NC_000918.1 hypothetical protein 1140756 1193171 aq_1625 Aquifex aeolicus VF5 hypothetical protein NP_214113.1 1140007 D 224324 CDS NP_214114.1 15606734 1193172 1140765..1141145 1 NC_000918.1 hypothetical protein 1141145 1193172 aq_1627 Aquifex aeolicus VF5 hypothetical protein NP_214114.1 1140765 D 224324 CDS NP_214115.1 15606735 1193173 1141158..1142027 1 NC_000918.1 DNA polymerase I 1142027 pol 1193173 pol Aquifex aeolicus VF5 DNA polymerase I NP_214115.1 1141158 D 224324 CDS NP_214116.1 15606736 1193174 complement(1142009..1142857) 1 NC_000918.1 deoxyribonuclease IV 1142857 nfo 1193174 nfo Aquifex aeolicus VF5 deoxyribonuclease IV NP_214116.1 1142009 R 224324 CDS NP_214117.1 15606737 1193175 complement(1142857..1143834) 1 NC_000918.1 hypothetical protein 1143834 1193175 aq_1630 Aquifex aeolicus VF5 hypothetical protein NP_214117.1 1142857 R 224324 CDS NP_214118.1 15606738 1193176 complement(1143906..1144397) 1 NC_000918.1 hypothetical protein 1144397 1193176 aq_1631 Aquifex aeolicus VF5 hypothetical protein NP_214118.1 1143906 R 224324 CDS NP_214119.1 15606739 1193177 complement(1144450..1145574) 1 NC_000918.1 hypothetical protein 1145574 1193177 aq_1632 Aquifex aeolicus VF5 hypothetical protein NP_214119.1 1144450 R 224324 CDS NP_214120.1 15606740 1193178 1145742..1146683 1 NC_000918.1 glycerol-3-phosphate dehydrogenase 1146683 gspA 1193178 gspA Aquifex aeolicus VF5 glycerol-3-phosphate dehydrogenase NP_214120.1 1145742 D 224324 CDS NP_214121.1 15606741 1193179 complement(1146815..1147750) 1 NC_000918.1 phosphoribosylpyrophosphate synthetase 1147750 prs 1193179 prs Aquifex aeolicus VF5 phosphoribosylpyrophosphate synthetase NP_214121.1 1146815 R 224324 CDS NP_214122.1 15606742 1193180 complement(1147879..1150245) 1 NC_000918.1 lipoate-protein ligase A 1150245 lplA 1193180 lplA Aquifex aeolicus VF5 lipoate-protein ligase A NP_214122.1 1147879 R 224324 CDS NP_214123.1 15606743 1193181 1150163..1151350 1 NC_000918.1 oxido/reductase iron sulfur protein 1151350 glpC 1193181 glpC Aquifex aeolicus VF5 oxido/reductase iron sulfur protein NP_214123.1 1150163 D 224324 CDS NP_214124.1 15606744 1193182 complement(1151528..1152493) 1 NC_000918.1 hypothetical protein 1152493 1193182 aq_1640 Aquifex aeolicus VF5 hypothetical protein NP_214124.1 1151528 R 224324 CDS NP_214125.1 15606745 1193183 1152537..1153487 1 NC_000918.1 capsular polysaccharide biosynthsis protein 1153487 cap 1193183 cap Aquifex aeolicus VF5 capsular polysaccharide biosynthsis protein NP_214125.1 1152537 D 224324 CDS NP_214126.1 15606746 1193184 complement(1153904..1154200) 1 NC_000918.1 50S ribosomal protein L21 1154200 rplU 1193184 rplU Aquifex aeolicus VF5 50S ribosomal protein L21 NP_214126.1 1153904 R 224324 CDS NP_214127.1 15606747 1193185 complement(1154212..1154661) 1 NC_000918.1 50S ribosomal protein L15 1154661 rplO 1193185 rplO Aquifex aeolicus VF5 50S ribosomal protein L15 NP_214127.1 1154212 R 224324 CDS NP_214128.1 15606748 1193278 complement(1154674..1155051) 1 NC_000918.1 50S ribosomal protein L30 1155051 rpmD 1193278 rpmD Aquifex aeolicus VF5 50S ribosomal protein L30 NP_214128.1 1154674 R 224324 CDS NP_214129.1 15606749 1193279 complement(1155038..1155664) 1 NC_000918.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1155664 rpsE 1193279 rpsE Aquifex aeolicus VF5 30S ribosomal protein S5 NP_214129.1 1155038 R 224324 CDS NP_214130.1 15606750 1193280 complement(1155676..1156050) 1 NC_000918.1 50S ribosomal protein L18 1156050 rplR 1193280 rplR Aquifex aeolicus VF5 50S ribosomal protein L18 NP_214130.1 1155676 R 224324 CDS NP_214131.1 15606751 1193281 complement(1156063..1156614) 1 NC_000918.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1156614 rplF 1193281 rplF Aquifex aeolicus VF5 50S ribosomal protein L6 NP_214131.1 1156063 R 224324 CDS NP_214132.1 15606752 1193282 complement(1156627..1157133) 1 NC_000918.1 ribosomal protein S08 1157133 rpsH 1193282 rpsH Aquifex aeolicus VF5 ribosomal protein S08 NP_214132.1 1156627 R 224324 CDS NP_214133.1 15606753 1193283 complement(1157174..1157362) 1 NC_000918.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 1157362 rpsN 1193283 rpsN Aquifex aeolicus VF5 30S ribosomal protein S14 NP_214133.1 1157174 R 224324 CDS NP_214134.1 15606754 1193284 complement(1157396..1157962) 1 NC_000918.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1157962 rplE 1193284 rplE Aquifex aeolicus VF5 50S ribosomal protein L5 NP_214134.1 1157396 R 224324 CDS NP_214135.1 15606755 1193285 complement(1157964..1158362) 1 NC_000918.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1158362 rplX 1193285 rplX Aquifex aeolicus VF5 50S ribosomal protein L24 NP_214135.1 1157964 R 224324 CDS NP_214136.1 15606756 1193286 complement(1158362..1158727) 1 NC_000918.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1158727 rplN 1193286 rplN Aquifex aeolicus VF5 50S ribosomal protein L14 NP_214136.1 1158362 R 224324 CDS NP_214137.1 15606757 1193287 1158873..1159421 1 NC_000918.1 hypothetical protein 1159421 1193287 aq_1655 Aquifex aeolicus VF5 hypothetical protein NP_214137.1 1158873 D 224324 CDS NP_214138.1 15606758 1193288 1159408..1160355 1 NC_000918.1 hypothetical protein 1160355 1193288 aq_1656 Aquifex aeolicus VF5 hypothetical protein NP_214138.1 1159408 D 224324 CDS NP_214139.1 15606759 1193289 complement(1160333..1160818) 1 NC_000918.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 1160818 gcsH2 1193289 gcsH2 Aquifex aeolicus VF5 glycine cleavage system protein H NP_214139.1 1160333 R 224324 CDS NP_214140.1 15606760 1193290 complement(1160802..1161365) 1 NC_000918.1 fuculose-1-phosphate aldolase 1161365 fucA1 1193290 fucA1 Aquifex aeolicus VF5 fuculose-1-phosphate aldolase NP_214140.1 1160802 R 224324 CDS NP_214141.1 15606761 1193291 complement(1161414..1162136) 1 NC_000918.1 catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A; 6-carboxyhexanoate--CoA ligase 1162136 bioW 1193291 bioW Aquifex aeolicus VF5 6-carboxyhexanoate--CoA ligase NP_214141.1 1161414 R 224324 CDS NP_214142.1 15606762 1193292 1162147..1162665 1 NC_000918.1 hypothetical protein 1162665 1193292 aq_1660 Aquifex aeolicus VF5 hypothetical protein NP_214142.1 1162147 D 224324 CDS NP_214143.1 15606763 1193293 complement(1162651..1163286) 1 NC_000918.1 rRNA methylase SpoU 1163286 spoU 1193293 spoU Aquifex aeolicus VF5 rRNA methylase SpoU NP_214143.1 1162651 R 224324 CDS NP_214144.1 15606764 1193294 1163541..1164821 1 NC_000918.1 flagellar hook associated protein FlgK 1164821 flgK 1193294 flgK Aquifex aeolicus VF5 flagellar hook associated protein FlgK NP_214144.1 1163541 D 224324 CDS NP_214145.1 15606765 1193295 1164831..1166099 1 NC_000918.1 flagellar hook associated protein FlgL 1166099 flgL 1193295 flgL Aquifex aeolicus VF5 flagellar hook associated protein FlgL NP_214145.1 1164831 D 224324 CDS NP_214146.1 15606766 1193296 complement(1166096..1167430) 1 NC_000918.1 biotin carboxylase 1167430 accC1 1193296 accC1 Aquifex aeolicus VF5 biotin carboxylase NP_214146.1 1166096 R 224324 CDS NP_214147.1 15606767 1193297 complement(1167443..1168447) 1 NC_000918.1 malate dehydrogenase 1168447 mdh2 1193297 mdh2 Aquifex aeolicus VF5 malate dehydrogenase NP_214147.1 1167443 R 224324 CDS NP_214148.1 15606768 1193298 complement(1168398..1168979) 1 NC_000918.1 hypothetical protein 1168979 1193298 aq_1666 Aquifex aeolicus VF5 hypothetical protein NP_214148.1 1168398 R 224324 CDS NP_214149.1 15606769 1193299 complement(1169232..1171148) 1 NC_000918.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1171148 thrS 1193299 thrS Aquifex aeolicus VF5 threonyl-tRNA synthetase NP_214149.1 1169232 R 224324 CDS NP_214150.1 15606770 1193300 1171185..1172066 1 NC_000918.1 hypothetical protein 1172066 1193300 aq_1668 Aquifex aeolicus VF5 hypothetical protein NP_214150.1 1171185 D 224324 CDS NP_214151.1 15606771 1193301 1172063..1172557 1 NC_000918.1 hypothetical protein 1172557 1193301 aq_1669 Aquifex aeolicus VF5 hypothetical protein NP_214151.1 1172063 D 224324 CDS NP_214152.1 15606772 1193302 1172557..1173765 1 NC_000918.1 hypothetical protein 1173765 1193302 aq_1670 Aquifex aeolicus VF5 hypothetical protein NP_214152.1 1172557 D 224324 CDS NP_214153.1 15606773 1193303 1173775..1174305 1 NC_000918.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1174305 hslV 1193303 hslV Aquifex aeolicus VF5 ATP-dependent protease peptidase subunit NP_214153.1 1173775 D 224324 CDS NP_214154.1 15606774 1193304 complement(1174423..1177443) 1 NC_000918.1 ATPase subunit of ATP-dependent protease 1177443 clpB 1193304 clpB Aquifex aeolicus VF5 ATPase subunit of ATP-dependent protease NP_214154.1 1174423 R 224324 CDS NP_214155.1 15606775 1193305 1177548..1179359 1 NC_000918.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1179359 aspS 1193305 aspS Aquifex aeolicus VF5 aspartyl-tRNA synthetase NP_214155.1 1177548 D 224324 CDS NP_214156.1 15606776 1193306 1179364..1179921 1 NC_000918.1 C-terminal fumarate hydratase, class I 1179921 fumX 1193306 fumX Aquifex aeolicus VF5 C-terminal fumarate hydratase, class I NP_214156.1 1179364 D 224324 CDS NP_214157.1 15606777 1193307 1179914..1180711 1 NC_000918.1 hypothetical protein 1180711 1193307 aq_1680 Aquifex aeolicus VF5 hypothetical protein NP_214157.1 1179914 D 224324 CDS NP_214158.1 15606778 1193308 complement(1180692..1181771) 1 NC_000918.1 N-acetylmuramoyl-L-alanine amidase 1181771 amiB 1193308 amiB Aquifex aeolicus VF5 N-acetylmuramoyl-L-alanine amidase NP_214158.1 1180692 R 224324 CDS NP_214159.1 15606779 1193309 complement(1181743..1183401) 1 NC_000918.1 hypothetical protein 1183401 1193309 aq_1682 Aquifex aeolicus VF5 hypothetical protein NP_214159.1 1181743 R 224324 CDS NP_214160.1 15606780 1193310 complement(1183451..1186099) 1 NC_000918.1 alginate synthesis-related protein 1186099 alg 1193310 alg Aquifex aeolicus VF5 alginate synthesis-related protein NP_214160.1 1183451 R 224324 CDS NP_214161.1 15606781 1193311 complement(1186099..1187541) 1 NC_000918.1 hypothetical protein 1187541 1193311 aq_1687 Aquifex aeolicus VF5 hypothetical protein NP_214161.1 1186099 R 224324 CDS NP_214162.1 15606782 1193312 complement(1187534..1189078) 1 NC_000918.1 hypothetical protein 1189078 1193312 aq_1689 Aquifex aeolicus VF5 hypothetical protein NP_214162.1 1187534 R 224324 CDS NP_214163.1 15606783 1193313 1189111..1189527 1 NC_000918.1 hypothetical protein 1189527 1193313 aq_1691 Aquifex aeolicus VF5 hypothetical protein NP_214163.1 1189111 D 224324 CDS NP_214164.1 15606784 1193314 1189596..1190183 1 NC_000918.1 N-terminus of phage SPO1 DNA polymerase 1190183 dplF 1193314 dplF Aquifex aeolicus VF5 N-terminus of phage SPO1 DNA polymerase NP_214164.1 1189596 D 224324 CDS NP_214165.1 15606785 1193315 complement(1190170..1190883) 1 NC_000918.1 hypothetical protein 1190883 1193315 aq_1694 Aquifex aeolicus VF5 hypothetical protein NP_214165.1 1190170 R 224324 CDS NP_214166.1 15606786 1193316 complement(1190915..1191805) 1 NC_000918.1 hypothetical protein 1191805 1193316 aq_1695 Aquifex aeolicus VF5 hypothetical protein NP_214166.1 1190915 R 224324 CDS NP_214167.1 15606787 1194001 complement(1197190..1198440) 1 NC_000918.1 hypothetical protein 1198440 1194001 aq_1695a Aquifex aeolicus VF5 hypothetical protein NP_214167.1 1197190 R 224324 CDS NP_214168.1 15606788 1193317 complement(1198437..1199330) 1 NC_000918.1 UDP-glucose pyrophosphorylase 1199330 galF 1193317 galF Aquifex aeolicus VF5 UDP-glucose pyrophosphorylase NP_214168.1 1198437 R 224324 CDS NP_214169.1 15606789 1193318 complement(1199317..1199841) 1 NC_000918.1 hypothetical protein 1199841 1193318 aq_1706 Aquifex aeolicus VF5 hypothetical protein NP_214169.1 1199317 R 224324 CDS NP_214170.1 15606790 1193319 complement(1199835..1200458) 1 NC_000918.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1200458 ribC 1193319 ribC Aquifex aeolicus VF5 riboflavin synthase subunit alpha NP_214170.1 1199835 R 224324 CDS NP_214171.1 15606791 1193320 complement(1200460..1201425) 1 NC_000918.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1201425 pfkA 1193320 pfkA Aquifex aeolicus VF5 6-phosphofructokinase NP_214171.1 1200460 R 224324 CDS NP_214172.1 15606792 1193321 complement(1201422..1203707) 1 NC_000918.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 1203707 metE 1193321 metE Aquifex aeolicus VF5 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase NP_214172.1 1201422 R 224324 CDS NP_214173.1 15606793 1193322 1203752..1204672 1 NC_000918.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1204672 argF 1193322 argF Aquifex aeolicus VF5 ornithine carbamoyltransferase NP_214173.1 1203752 D 224324 CDS NP_214174.1 15606794 1193323 complement(1204653..1205735) 1 NC_000918.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1205735 flgI 1193323 flgI Aquifex aeolicus VF5 flagellar basal body P-ring protein NP_214174.1 1204653 R 224324 CDS NP_214175.1 15606795 1193324 complement(1205696..1206346) 1 NC_000918.1 flagellar L-ring protein FlgH 1206346 flgH 1193324 flgH Aquifex aeolicus VF5 flagellar L-ring protein FlgH NP_214175.1 1205696 R 224324 CDS NP_214176.1 15606796 1193325 1206406..1207152 1 NC_000918.1 3-oxoacyl-ACP reductase 1207152 fabG 1193325 fabG Aquifex aeolicus VF5 3-oxoacyl-ACP reductase NP_214176.1 1206406 D 224324 CDS NP_214177.1 15606797 1193326 1207165..1207401 1 NC_000918.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1207401 acpP 1193326 acpP Aquifex aeolicus VF5 acyl carrier protein NP_214177.1 1207165 D 224324 CDS NP_214178.1 15606798 1193327 1207398..1208645 1 NC_000918.1 3-oxoacyl-ACP synthase 1208645 fabF 1193327 fabF Aquifex aeolicus VF5 3-oxoacyl-ACP synthase NP_214178.1 1207398 D 224324 CDS NP_214179.1 15606799 1193328 1208642..1209214 1 NC_000918.1 MAF protein 1209214 maf 1193328 maf Aquifex aeolicus VF5 MAF protein NP_214179.1 1208642 D 224324 CDS NP_214180.1 15606800 1193329 complement(1209385..1209780) 1 NC_000918.1 hypothetical protein 1209780 1193329 aq_1719 Aquifex aeolicus VF5 hypothetical protein NP_214180.1 1209385 R 224324 CDS NP_214181.1 15606801 1193330 complement(1209812..1211176) 1 NC_000918.1 signal recognition particle receptor protein 1211176 ffh 1193330 ffh Aquifex aeolicus VF5 signal recognition particle receptor protein NP_214181.1 1209812 R 224324 CDS NP_214182.1 15606802 1193331 complement(1211217..1212374) 1 NC_000918.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 1212374 truD 1193331 truD Aquifex aeolicus VF5 tRNA pseudouridine synthase D NP_214182.1 1211217 R 224324 CDS NP_214183.1 15606803 1193332 1212399..1213439 1 NC_000918.1 DegT/DnrJ/Eryc1 family transcriptional regulator 1213439 degT 1193332 degT Aquifex aeolicus VF5 DegT/DnrJ/Eryc1 family transcriptional regulator NP_214183.1 1212399 D 224324 CDS NP_214184.1 15606804 1193333 1213458..1215260 1 NC_000918.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1215260 lepA 1193333 lepA Aquifex aeolicus VF5 GTP-binding protein LepA NP_214184.1 1213458 D 224324 CDS NP_214185.1 15606805 1193334 complement(1215237..1216169) 1 NC_000918.1 hypothetical protein 1216169 1193334 aq_1727 Aquifex aeolicus VF5 hypothetical protein NP_214185.1 1215237 R 224324 CDS YP_008920734.1 566344054 17925353 complement(1216818..1217123) 1 NC_000918.1 hypothetical protein 1217123 17925353 aq_1727a Aquifex aeolicus VF5 hypothetical protein YP_008920734.1 1216818 R 224324 CDS YP_008920735.1 566344055 17925354 complement(1217120..1217353) 1 NC_000918.1 SirA family protein 1217353 17925354 aq_1730a Aquifex aeolicus VF5 SirA family protein YP_008920735.1 1217120 R 224324 CDS NP_214186.1 15606806 1193335 1217400..1219727 1 NC_000918.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1219727 pheT 1193335 pheT Aquifex aeolicus VF5 phenylalanyl-tRNA synthetase subunit beta NP_214186.1 1217400 D 224324 CDS NP_214187.1 15606807 1193336 1219923..1220483 1 NC_000918.1 hypothetical protein 1220483 1193336 aq_1731 Aquifex aeolicus VF5 hypothetical protein NP_214187.1 1219923 D 224324 CDS NP_214188.1 15606808 1193337 1220470..1222146 1 NC_000918.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1222146 1193337 aq_1732 Aquifex aeolicus VF5 phosphodiesterase NP_214188.1 1220470 D 224324 CDS NP_214189.1 15606809 1193338 1222227..1223321 1 NC_000918.1 chaperone DnaJ 1223321 dnaJ1 1193338 dnaJ1 Aquifex aeolicus VF5 chaperone DnaJ NP_214189.1 1222227 D 224324 CDS NP_214190.1 15606810 1193339 complement(1223292..1224494) 1 NC_000918.1 cyclopropane-fatty-acyl-phospholipid synthase 1224494 cfa 1193339 cfa Aquifex aeolicus VF5 cyclopropane-fatty-acyl-phospholipid synthase NP_214190.1 1223292 R 224324 CDS NP_214191.1 15606811 1193340 1224574..1225443 1 NC_000918.1 LytB protein 1225443 lytB 1193340 lytB Aquifex aeolicus VF5 LytB protein NP_214191.1 1224574 D 224324 CDS NP_214192.1 15606812 1193341 1225416..1225934 1 NC_000918.1 hypothetical protein 1225934 1193341 aq_1740 Aquifex aeolicus VF5 hypothetical protein NP_214192.1 1225416 D 224324 CDS NP_214193.1 15606813 1193342 complement(1225914..1226345) 1 NC_000918.1 hypothetical protein 1226345 1193342 aq_1741 Aquifex aeolicus VF5 hypothetical protein NP_214193.1 1225914 R 224324 CDS NP_214194.1 15606814 1193343 complement(1226887..1227642) 1 NC_000918.1 beta 1,4 glucosyltransferase 1227642 lgtF 1193343 lgtF Aquifex aeolicus VF5 beta 1,4 glucosyltransferase NP_214194.1 1226887 R 224324 CDS NP_214195.1 15606815 1193344 1227660..1228937 1 NC_000918.1 hypothetical protein 1228937 1193344 aq_1743 Aquifex aeolicus VF5 hypothetical protein NP_214195.1 1227660 D 224324 CDS NP_214196.1 15606816 1193345 complement(1228916..1229578) 1 NC_000918.1 phosphoglycerate mutase 1229578 gpmA 1193345 gpmA Aquifex aeolicus VF5 phosphoglycerate mutase NP_214196.1 1228916 R 224324 CDS NP_214197.1 15606817 1193346 complement(1229799..1231247) 1 NC_000918.1 UDP-MurNac-tripeptide synthetase 1231247 murE 1193346 murE Aquifex aeolicus VF5 UDP-MurNac-tripeptide synthetase NP_214197.1 1229799 R 224324 CDS NP_214198.1 15606818 1193347 complement(1232471..1233649) 1 NC_000918.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1233649 tyrS 1193347 tyrS Aquifex aeolicus VF5 tyrosyl-tRNA synthetase NP_214198.1 1232471 R 224324 CDS NP_214199.1 15606819 1193348 1233688..1234239 1 NC_000918.1 hypothetical protein 1234239 1193348 aq_1752 Aquifex aeolicus VF5 hypothetical protein NP_214199.1 1233688 D 224324 CDS NP_214200.1 15606820 1193349 complement(1234236..1234799) 1 NC_000918.1 lipoprotein NlpD fragment 1234799 nlpD2 1193349 nlpD2 Aquifex aeolicus VF5 lipoprotein NlpD fragment NP_214200.1 1234236 R 224324 CDS NP_214201.1 15606821 1193350 complement(1234777..1235844) 1 NC_000918.1 hypothetical protein 1235844 1193350 aq_1754 Aquifex aeolicus VF5 hypothetical protein NP_214201.1 1234777 R 224324 CDS NP_214202.1 15606822 1193351 1235819..1236754 1 NC_000918.1 prephenate dehydrogenase 1236754 tyrA 1193351 tyrA Aquifex aeolicus VF5 prephenate dehydrogenase NP_214202.1 1235819 D 224324 CDS NP_214203.1 15606823 1193352 1236751..1237197 1 NC_000918.1 biopolymer transport exbB 1237197 exbB 1193352 exbB Aquifex aeolicus VF5 biopolymer transport exbB NP_214203.1 1236751 D 224324 CDS NP_214204.1 15606824 1193353 complement(1237167..1238117) 1 NC_000918.1 hypothetical protein 1238117 1193353 aq_1758 Aquifex aeolicus VF5 hypothetical protein NP_214204.1 1237167 R 224324 CDS NP_214205.1 15606825 1193354 complement(1238129..1238974) 1 NC_000918.1 hypothetical protein 1238974 1193354 aq_1760 Aquifex aeolicus VF5 hypothetical protein NP_214205.1 1238129 R 224324 CDS NP_214206.1 15606826 1193355 complement(1239007..1241043) 1 NC_000918.1 hypothetical protein 1241043 1193355 aq_1761 Aquifex aeolicus VF5 hypothetical protein NP_214206.1 1239007 R 224324 CDS YP_008920736.1 566344056 17925355 complement(1241054..1241488) 1 NC_000918.1 hypothetical protein 1241488 17925355 aq_1761a Aquifex aeolicus VF5 hypothetical protein YP_008920736.1 1241054 R 224324 CDS NP_214207.1 15606827 1193356 1241651..1242745 1 NC_000918.1 hypothetical protein 1242745 1193356 aq_1763 Aquifex aeolicus VF5 hypothetical protein NP_214207.1 1241651 D 224324 CDS NP_214208.1 15606828 1193357 1243042..1245111 1 NC_000918.1 transketolase 1245111 tktA 1193357 tktA Aquifex aeolicus VF5 transketolase NP_214208.1 1243042 D 224324 CDS NP_214209.1 15606829 1193358 1245177..1245518 1 NC_000918.1 30S ribosomal protein S20 1245518 rpsT 1193358 rpsT Aquifex aeolicus VF5 30S ribosomal protein S20 NP_214209.1 1245177 D 224324 CDS NP_214210.1 15606830 1193359 1245528..1246301 1 NC_000918.1 hypothetical protein 1246301 1193359 aq_1768 Aquifex aeolicus VF5 hypothetical protein NP_214210.1 1245528 D 224324 CDS NP_214211.1 15606831 1193360 complement(1246568..1248016) 1 NC_000918.1 D-lactate dehydrogenase 1248016 dld1 1193360 dld1 Aquifex aeolicus VF5 D-lactate dehydrogenase NP_214211.1 1246568 R 224324 CDS NP_214212.1 15606832 1193361 complement(1248006..1248875) 1 NC_000918.1 leucyl-tRNA synthetase 1248875 leuS' 1193361 leuS' Aquifex aeolicus VF5 leucyl-tRNA synthetase NP_214212.1 1248006 R 224324 CDS NP_214213.1 15606833 1193362 1249334..1250086 1 NC_000918.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1250086 hemD 1193362 hemD Aquifex aeolicus VF5 uroporphyrinogen-III synthase NP_214213.1 1249334 D 224324 CDS NP_214214.1 15606834 1193363 1250094..1250942 1 NC_000918.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1250942 lpxC 1193363 lpxC Aquifex aeolicus VF5 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NP_214214.1 1250094 D 224324 CDS NP_214215.1 15606835 1193364 complement(1250899..1251639) 1 NC_000918.1 hypothetical protein 1251639 1193364 aq_1773 Aquifex aeolicus VF5 hypothetical protein NP_214215.1 1250899 R 224324 CDS NP_214216.1 15606836 1193365 1251717..1252013 1 NC_000918.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1252013 rpmA 1193365 rpmA Aquifex aeolicus VF5 50S ribosomal protein L27 NP_214216.1 1251717 D 224324 CDS NP_214218.1 15606838 1193367 complement(1254811..1255521) 1 NC_000918.1 hypothetical protein 1255521 1193367 aq_1776 Aquifex aeolicus VF5 hypothetical protein NP_214218.1 1254811 R 224324 CDS NP_214219.1 15606839 1193368 complement(1255532..1256059) 1 NC_000918.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1256059 infC 1193368 infC Aquifex aeolicus VF5 translation initiation factor IF-3 NP_214219.1 1255532 R 224324 CDS NP_214220.1 15606840 1193369 complement(1256565..1257410) 1 NC_000918.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; fumarate hydratase 1257410 fumB 1193369 fumB Aquifex aeolicus VF5 fumarate hydratase NP_214220.1 1256565 R 224324 CDS NP_214221.1 15606841 1193462 complement(1257388..1258395) 1 NC_000918.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1258395 mdh1 1193462 mdh1 Aquifex aeolicus VF5 malate dehydrogenase NP_214221.1 1257388 R 224324 CDS NP_214222.1 15606842 1193463 complement(1258392..1260371) 1 NC_000918.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1260371 aco 1193463 aco Aquifex aeolicus VF5 aconitate hydratase NP_214222.1 1258392 R 224324 CDS NP_214223.1 15606843 1193464 complement(1260424..1261197) 1 NC_000918.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1261197 trpC 1193464 trpC Aquifex aeolicus VF5 indole-3-glycerol-phosphate synthase NP_214223.1 1260424 R 224324 CDS NP_214224.1 15606844 1193465 complement(1261151..1262650) 1 NC_000918.1 virulence factor MviB 1262650 mviB 1193465 mviB Aquifex aeolicus VF5 virulence factor MviB NP_214224.1 1261151 R 224324 CDS NP_214225.1 15606845 1193466 complement(1262655..1263800) 1 NC_000918.1 hypothetical protein 1263800 1193466 aq_1790 Aquifex aeolicus VF5 hypothetical protein NP_214225.1 1262655 R 224324 CDS NP_214226.1 15606846 1193467 complement(1263813..1264196) 1 NC_000918.1 hypothetical protein 1264196 1193467 aq_1791 Aquifex aeolicus VF5 hypothetical protein NP_214226.1 1263813 R 224324 CDS NP_214227.1 15606847 1193468 complement(1264237..1265730) 1 NC_000918.1 NtrC family transcriptional regulator 1265730 ntrC2 1193468 ntrC2 Aquifex aeolicus VF5 NtrC family transcriptional regulator NP_214227.1 1264237 R 224324 CDS NP_214228.1 15606848 1193469 complement(1265940..1266749) 1 NC_000918.1 hypothetical protein 1266749 1193469 aq_1793 Aquifex aeolicus VF5 hypothetical protein NP_214228.1 1265940 R 224324 CDS NP_214229.1 15606849 1193470 1266721..1267503 1 NC_000918.1 hypothetical protein 1267503 1193470 aq_1794 Aquifex aeolicus VF5 hypothetical protein NP_214229.1 1266721 D 224324 CDS NP_214230.1 15606850 1193471 1267500..1268042 1 NC_000918.1 hypothetical protein 1268042 1193471 aq_1795 Aquifex aeolicus VF5 hypothetical protein NP_214230.1 1267500 D 224324 CDS NP_214231.1 15606851 1193472 1268039..1269118 1 NC_000918.1 hypothetical protein 1269118 1193472 aq_1796 Aquifex aeolicus VF5 hypothetical protein NP_214231.1 1268039 D 224324 CDS NP_214232.1 15606852 1193473 complement(1269101..1269493) 1 NC_000918.1 hypothetical protein 1269493 1193473 aq_1797 Aquifex aeolicus VF5 hypothetical protein NP_214232.1 1269101 R 224324 CDS NP_214233.1 15606853 1193474 complement(1269541..1270521) 1 NC_000918.1 beta lactamase 1270521 cphA1 1193474 cphA1 Aquifex aeolicus VF5 beta lactamase NP_214233.1 1269541 R 224324 CDS NP_214234.1 15606854 1193475 complement(1270543..1271424) 1 NC_000918.1 thiosulfate sulfurtransferase 1271424 rhdA2 1193475 rhdA2 Aquifex aeolicus VF5 thiosulfate sulfurtransferase NP_214234.1 1270543 R 224324 CDS NP_214235.1 15606855 1193476 complement(1271426..1271860) 1 NC_000918.1 hypothetical protein 1271860 1193476 aq_1800 Aquifex aeolicus VF5 hypothetical protein NP_214235.1 1271426 R 224324 CDS NP_214236.1 15606856 1193477 complement(1271857..1272345) 1 NC_000918.1 hypothetical protein 1272345 1193477 aq_1802 Aquifex aeolicus VF5 hypothetical protein NP_214236.1 1271857 R 224324 CDS NP_214237.1 15606857 1193478 complement(1272342..1274120) 1 NC_000918.1 sulfur oxidation protein SoxB 1274120 soxB 1193478 soxB Aquifex aeolicus VF5 sulfur oxidation protein SoxB NP_214237.1 1272342 R 224324 CDS NP_214238.1 15606858 1193479 complement(1274166..1274786) 1 NC_000918.1 hypothetical protein 1274786 1193479 aq_1806 Aquifex aeolicus VF5 hypothetical protein NP_214238.1 1274166 R 224324 CDS NP_214239.1 15606859 1193480 complement(1274799..1275602) 1 NC_000918.1 hypothetical protein 1275602 1193480 aq_1807 Aquifex aeolicus VF5 hypothetical protein NP_214239.1 1274799 R 224324 CDS NP_214240.1 15606860 1193481 complement(1275616..1275948) 1 NC_000918.1 hypothetical protein 1275948 1193481 aq_1809 Aquifex aeolicus VF5 hypothetical protein NP_214240.1 1275616 R 224324 CDS NP_214241.1 15606861 1193482 complement(1275970..1276431) 1 NC_000918.1 hypothetical protein 1276431 1193482 aq_1810 Aquifex aeolicus VF5 hypothetical protein NP_214241.1 1275970 R 224324 CDS NP_214242.1 15606862 1193483 complement(1276425..1276832) 1 NC_000918.1 thioredoxin 1276832 trxA2 1193483 trxA2 Aquifex aeolicus VF5 thioredoxin NP_214242.1 1276425 R 224324 CDS NP_214243.1 15606863 1193484 1277001..1278308 1 NC_000918.1 homoserine dehydrogenase 1278308 thrA 1193484 thrA Aquifex aeolicus VF5 homoserine dehydrogenase NP_214243.1 1277001 D 224324 CDS NP_214244.1 15606864 1193485 1278313..1279044 1 NC_000918.1 hypothetical protein 1279044 1193485 aq_1814 Aquifex aeolicus VF5 hypothetical protein NP_214244.1 1278313 D 224324 CDS NP_214245.1 15606865 1193486 1279051..1279602 1 NC_000918.1 hypothetical protein 1279602 1193486 aq_1815 Aquifex aeolicus VF5 hypothetical protein NP_214245.1 1279051 D 224324 CDS NP_214246.1 15606866 1193487 complement(1279579..1280325) 1 NC_000918.1 dimethyladenosine transferase 1280325 ksgA 1193487 ksgA Aquifex aeolicus VF5 dimethyladenosine transferase NP_214246.1 1279579 R 224324 CDS NP_214247.1 15606867 1193488 1280345..1281196 1 NC_000918.1 formyltetrahydrofolate deformylase 1281196 purU 1193488 purU Aquifex aeolicus VF5 formyltetrahydrofolate deformylase NP_214247.1 1280345 D 224324 CDS NP_214248.1 15606868 1193489 1281207..1282484 1 NC_000918.1 nodulation competitiveness protein NfeD 1282484 nfeD 1193489 nfeD Aquifex aeolicus VF5 nodulation competitiveness protein NfeD NP_214248.1 1281207 D 224324 CDS NP_214249.1 15606869 1193490 1282506..1282994 1 NC_000918.1 hypothetical protein 1282994 1193490 aq_1822 Aquifex aeolicus VF5 hypothetical protein NP_214249.1 1282506 D 224324 CDS NP_214251.1 15606871 1193492 1283539..1284606 1 NC_000918.1 hypothetical protein 1284606 1193492 aq_1824 Aquifex aeolicus VF5 hypothetical protein NP_214251.1 1283539 D 224324 CDS NP_214252.1 15606872 1193493 1284587..1285486 1 NC_000918.1 hypothetical protein 1285486 1193493 aq_1825 Aquifex aeolicus VF5 hypothetical protein NP_214252.1 1284587 D 224324 CDS NP_214253.1 15606873 1193494 1285739..1286755 1 NC_000918.1 alanine racemase 1286755 alr 1193494 alr Aquifex aeolicus VF5 alanine racemase NP_214253.1 1285739 D 224324 CDS NP_214254.1 15606874 1194002 complement(1286704..1287396) 1 NC_000918.1 hypothetical protein 1287396 1194002 aq_1827a Aquifex aeolicus VF5 hypothetical protein NP_214254.1 1286704 R 224324 CDS NP_214255.1 15606875 1193495 complement(1287540..1287965) 1 NC_000918.1 hypothetical protein 1287965 1193495 aq_1829 Aquifex aeolicus VF5 hypothetical protein NP_214255.1 1287540 R 224324 CDS NP_214256.1 15606876 1193496 complement(1288398..1288880) 1 NC_000918.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1288880 rpsG1 1193496 rpsG1 Aquifex aeolicus VF5 30S ribosomal protein S7 NP_214256.1 1288398 R 224324 CDS NP_214257.1 15606877 1193497 complement(1288884..1289270) 1 NC_000918.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1289270 rpsL 1193497 rpsL Aquifex aeolicus VF5 30S ribosomal protein S12 NP_214257.1 1288884 R 224324 CDS NP_214258.1 15606878 1193498 1289323..1291560 1 NC_000918.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1291560 purL 1193498 purL Aquifex aeolicus VF5 phosphoribosylformylglycinamidine synthase II NP_214258.1 1289323 D 224324 CDS NP_214259.1 15606879 1193499 1291521..1292024 1 NC_000918.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1292024 lsp 1193499 lsp Aquifex aeolicus VF5 lipoprotein signal peptidase NP_214259.1 1291521 D 224324 CDS NP_214260.1 15606880 1193500 complement(1291962..1292801) 1 NC_000918.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1292801 dapF 1193500 dapF Aquifex aeolicus VF5 diaminopimelate epimerase NP_214260.1 1291962 R 224324 CDS NP_214261.1 15606881 1193501 1292807..1293205 1 NC_000918.1 biopolymer transport ExbD 1293205 exbD 1193501 exbD Aquifex aeolicus VF5 biopolymer transport ExbD NP_214261.1 1292807 D 224324 CDS NP_214262.1 15607140 1194008 1293221..1293427 1 NC_000918.1 copper chaperone 1293427 1194008 aq_1840a Aquifex aeolicus VF5 copper chaperone NP_214262.1 1293221 D 224324 CDS NP_214263.1 15606882 1193502 1293461..1294582 1 NC_000918.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 1294582 prfB 1193502 prfB Aquifex aeolicus VF5 peptide chain release factor 2 NP_214263.1 1293461 D 224324 CDS NP_214264.1 15606883 1193503 complement(1294568..1295440) 1 NC_000918.1 hypothetical protein 1295440 1193503 aq_1842 Aquifex aeolicus VF5 hypothetical protein NP_214264.1 1294568 R 224324 CDS NP_214265.1 15606884 1193504 complement(1295462..1296496) 1 NC_000918.1 hypothetical protein 1296496 1193504 aq_1843 Aquifex aeolicus VF5 hypothetical protein NP_214265.1 1295462 R 224324 CDS NP_214266.1 15606885 1193505 complement(1296612..1297172) 1 NC_000918.1 hypothetical protein 1297172 1193505 aq_1844 Aquifex aeolicus VF5 hypothetical protein NP_214266.1 1296612 R 224324 CDS NP_214267.1 15606886 1193506 complement(1297169..1297861) 1 NC_000918.1 hypothetical protein 1297861 1193506 aq_1845 Aquifex aeolicus VF5 hypothetical protein NP_214267.1 1297169 R 224324 CDS NP_214268.1 15606887 1193507 complement(1297865..1298218) 1 NC_000918.1 hypothetical protein 1298218 1193507 aq_1847 Aquifex aeolicus VF5 hypothetical protein NP_214268.1 1297865 R 224324 CDS NP_214269.1 15606888 1193508 complement(1298231..1298890) 1 NC_000918.1 hypothetical protein 1298890 1193508 aq_1849 Aquifex aeolicus VF5 hypothetical protein NP_214269.1 1298231 R 224324 CDS NP_214270.1 15606889 1193509 complement(1298926..1299558) 1 NC_000918.1 hypothetical protein 1299558 1193509 aq_1850 Aquifex aeolicus VF5 hypothetical protein NP_214270.1 1298926 R 224324 CDS NP_214271.1 15606890 1193510 complement(1299551..1300129) 1 NC_000918.1 acetolactate synthase 1300129 ilvH 1193510 ilvH Aquifex aeolicus VF5 acetolactate synthase NP_214271.1 1299551 R 224324 CDS NP_214272.1 15606891 1193511 1300157..1302034 1 NC_000918.1 hypothetical protein 1302034 1193511 aq_1852 Aquifex aeolicus VF5 hypothetical protein NP_214272.1 1300157 D 224324 CDS NP_214273.1 15606892 1193512 1302595..1303248 1 NC_000918.1 hypothetical protein 1303248 1193512 aq_1853 Aquifex aeolicus VF5 hypothetical protein NP_214273.1 1302595 D 224324 CDS NP_214274.1 15606893 1193513 complement(1303245..1303703) 1 NC_000918.1 hypothetical protein 1303703 1193513 aq_1854 Aquifex aeolicus VF5 hypothetical protein NP_214274.1 1303245 R 224324 CDS NP_214275.1 15606894 1193514 1303882..1305303 1 NC_000918.1 DNA polymerase III subunit gamma 1305303 dnaX 1193514 dnaX Aquifex aeolicus VF5 DNA polymerase III subunit gamma NP_214275.1 1303882 D 224324 CDS NP_214276.1 15606895 1193515 1305589..1307580 1 NC_000918.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1307580 uvrB 1193515 uvrB Aquifex aeolicus VF5 excinuclease ABC subunit B NP_214276.1 1305589 D 224324 CDS NP_214277.1 15606896 1193516 complement(1307598..1307948) 1 NC_000918.1 hypothetical protein 1307948 1193516 aq_1857 Aquifex aeolicus VF5 hypothetical protein NP_214277.1 1307598 R 224324 CDS NP_214278.1 15606897 1193517 1308165..1308794 1 NC_000918.1 flagellar hook assembly protein 1308794 1193517 aq_1858 Aquifex aeolicus VF5 flagellar hook assembly protein NP_214278.1 1308165 D 224324 CDS NP_214279.1 15606898 1193518 1308798..1310246 1 NC_000918.1 flagellar hook protein FlgE 1310246 flgE 1193518 flgE Aquifex aeolicus VF5 flagellar hook protein FlgE NP_214279.1 1308798 D 224324 CDS NP_214280.1 15606899 1193519 1310298..1310783 1 NC_000918.1 flagellar biosynthesis FliL 1310783 fliL 1193519 fliL Aquifex aeolicus VF5 flagellar biosynthesis FliL NP_214280.1 1310298 D 224324 CDS NP_214281.1 15606900 1193520 1310860..1311888 1 NC_000918.1 hypothetical protein 1311888 1193520 aq_1861 Aquifex aeolicus VF5 hypothetical protein NP_214281.1 1310860 D 224324 CDS NP_214282.1 15606901 1193521 complement(1311923..1313080) 1 NC_000918.1 hypothetical protein 1313080 1193521 aq_1862 Aquifex aeolicus VF5 hypothetical protein NP_214282.1 1311923 R 224324 CDS NP_214283.1 15606902 1193522 1313240..1314607 1 NC_000918.1 potassium channel protein 1314607 kch 1193522 kch Aquifex aeolicus VF5 potassium channel protein NP_214283.1 1313240 D 224324 CDS NP_214284.1 15606903 1193523 1315363..1316385 1 NC_000918.1 aspartate-semialdehyde dehydrogenase 1316385 asd 1193523 asd Aquifex aeolicus VF5 aspartate-semialdehyde dehydrogenase NP_214284.1 1315363 D 224324 CDS NP_214285.1 15606904 1193524 1316399..1316812 1 NC_000918.1 hypothetical protein 1316812 1193524 aq_1869 Aquifex aeolicus VF5 hypothetical protein NP_214285.1 1316399 D 224324 CDS NP_214286.1 15606905 1193525 1316869..1319823 1 NC_000918.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1319823 secA 1193525 secA Aquifex aeolicus VF5 preprotein translocase subunit SecA NP_214286.1 1316869 D 224324 CDS NP_214287.1 15606906 1193526 1319839..1321164 1 NC_000918.1 peptide maturation 1321164 pmbA 1193526 pmbA Aquifex aeolicus VF5 peptide maturation NP_214287.1 1319839 D 224324 CDS NP_214288.1 15606907 1193527 1321781..1323004 1 NC_000918.1 hypothetical protein 1323004 1193527 aq_1873 Aquifex aeolicus VF5 hypothetical protein NP_214288.1 1321781 D 224324 CDS NP_214289.1 15606908 1193528 1323017..1323901 1 NC_000918.1 S-adenosyl-methyltransferase MraW 1323901 mraW 1193528 mraW Aquifex aeolicus VF5 S-adenosyl-methyltransferase MraW NP_214289.1 1323017 D 224324 CDS NP_214290.1 15606909 1193529 1323947..1324381 1 NC_000918.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1324381 rplM 1193529 rplM Aquifex aeolicus VF5 50S ribosomal protein L13 NP_214290.1 1323947 D 224324 CDS NP_214291.1 15606910 1193530 1324378..1324821 1 NC_000918.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1324821 rpsI 1193530 rpsI Aquifex aeolicus VF5 30S ribosomal protein S9 NP_214291.1 1324378 D 224324 CDS NP_214292.1 15606911 1193531 1324806..1325828 1 NC_000918.1 N-acetyl-gamma-glutamylphosphate reductase 1325828 argC 1193531 argC Aquifex aeolicus VF5 N-acetyl-gamma-glutamylphosphate reductase NP_214292.1 1324806 D 224324 CDS NP_214293.1 15606912 1193532 1325853..1326944 1 NC_000918.1 DNA polymerase III subunit beta 1326944 dnaN 1193532 dnaN Aquifex aeolicus VF5 DNA polymerase III subunit beta NP_214293.1 1325853 D 224324 CDS NP_214294.1 15606913 1193533 1327171..1327923 1 NC_000918.1 hypothetical protein 1327923 1193533 aq_1884 Aquifex aeolicus VF5 hypothetical protein NP_214294.1 1327171 D 224324 CDS NP_214295.1 15606914 1193534 1327901..1329040 1 NC_000918.1 ATP-dependent dsDNA exonuclease 1329040 sbcD 1193534 sbcD Aquifex aeolicus VF5 ATP-dependent dsDNA exonuclease NP_214295.1 1327901 D 224324 CDS NP_214296.1 15606915 1193535 1329030..1329983 1 NC_000918.1 cell cycle protein MesJ 1329983 mesJ 1193535 mesJ Aquifex aeolicus VF5 cell cycle protein MesJ NP_214296.1 1329030 D 224324 CDS NP_214297.1 15606916 1193536 complement(1329967..1331073) 1 NC_000918.1 succinyl-CoA ligase subunit alpha 1331073 sucD1 1193536 sucD1 Aquifex aeolicus VF5 succinyl-CoA ligase subunit alpha NP_214297.1 1329967 R 224324 CDS NP_214298.1 15606917 1193537 1331127..1332095 1 NC_000918.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1332095 nadA 1193537 nadA Aquifex aeolicus VF5 quinolinate synthetase NP_214298.1 1331127 D 224324 CDS NP_214299.1 15606918 1193538 complement(1332092..1332814) 1 NC_000918.1 rRNA methylase 1332814 tsnR 1193538 tsnR Aquifex aeolicus VF5 rRNA methylase NP_214299.1 1332092 R 224324 CDS NP_214300.1 15606919 1193539 complement(1332824..1333930) 1 NC_000918.1 hypothetical protein 1333930 1193539 aq_1891 Aquifex aeolicus VF5 hypothetical protein NP_214300.1 1332824 R 224324 CDS NP_214301.1 15606920 1193540 complement(1333920..1334855) 1 NC_000918.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1334855 ilvE 1193540 ilvE Aquifex aeolicus VF5 branched-chain amino acid aminotransferase NP_214301.1 1333920 R 224324 CDS NP_214302.1 15606921 1193541 1334770..1335483 1 NC_000918.1 hypothetical protein 1335483 1193541 aq_1894 Aquifex aeolicus VF5 hypothetical protein NP_214302.1 1334770 D 224324 CDS NP_214303.1 15606922 1193542 1335480..1336508 1 NC_000918.1 hypothetical protein 1336508 1193542 aq_1896 Aquifex aeolicus VF5 hypothetical protein NP_214303.1 1335480 D 224324 CDS NP_214304.1 15606923 1193543 complement(1336481..1337356) 1 NC_000918.1 methylenetetrahydrofolate dehydrogenase 1337356 folD 1193543 folD Aquifex aeolicus VF5 methylenetetrahydrofolate dehydrogenase NP_214304.1 1336481 R 224324 CDS NP_214305.1 15606924 1193544 complement(1337340..1338308) 1 NC_000918.1 dolichol-phosphate mannosyltransferase 1338308 dmt 1193544 dmt Aquifex aeolicus VF5 dolichol-phosphate mannosyltransferase NP_214305.1 1337340 R 224324 CDS NP_214306.1 15606925 1194003 1338336..1338842 1 NC_000918.1 hypothetical protein 1338842 1194003 aq_1899a Aquifex aeolicus VF5 hypothetical protein NP_214306.1 1338336 D 224324 CDS NP_214307.1 15606926 1194004 1338855..1339262 1 NC_000918.1 hypothetical protein 1339262 1194004 aq_1899b Aquifex aeolicus VF5 hypothetical protein NP_214307.1 1338855 D 224324 CDS NP_214308.1 15606927 1193545 1339276..1340724 1 NC_000918.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 1340724 gcsP1 1193545 gcsP1 Aquifex aeolicus VF5 glycine dehydrogenase subunit 2 NP_214308.1 1339276 D 224324 CDS NP_214309.1 15606928 1193546 1340752..1342353 1 NC_000918.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1342353 serA 1193546 serA Aquifex aeolicus VF5 D-3-phosphoglycerate dehydrogenase NP_214309.1 1340752 D 224324 CDS NP_214310.1 15606929 1193547 1342372..1342923 1 NC_000918.1 uridine 5-monophosphate synthase 1342923 umpS 1193547 umpS Aquifex aeolicus VF5 uridine 5-monophosphate synthase NP_214310.1 1342372 D 224324 CDS NP_214311.1 15606930 1193548 complement(1342920..1344032) 1 NC_000918.1 GTP-binding protein HflX 1344032 hflX 1193548 hflX Aquifex aeolicus VF5 GTP-binding protein HflX NP_214311.1 1342920 R 224324 CDS YP_008920737.1 566344057 17925356 complement(1344072..1344287) 1 NC_000918.1 hypothetical protein 1344287 17925356 aq_1908a Aquifex aeolicus VF5 hypothetical protein YP_008920737.1 1344072 R 224324 CDS NP_214312.1 15606931 1193549 1344366..1345295 1 NC_000918.1 hypothetical protein 1345295 1193549 aq_1909 Aquifex aeolicus VF5 hypothetical protein NP_214312.1 1344366 D 224324 CDS NP_214313.1 15606932 1193550 1345378..1346493 1 NC_000918.1 hypothetical protein 1346493 1193550 aq_1910 Aquifex aeolicus VF5 hypothetical protein NP_214313.1 1345378 D 224324 CDS NP_214314.1 15606933 1193551 1346869..1348326 1 NC_000918.1 hypothetical protein 1348326 1193551 aq_1912 Aquifex aeolicus VF5 hypothetical protein NP_214314.1 1346869 D 224324 CDS NP_214315.1 15606934 1193552 1348671..1349090 1 NC_000918.1 thioredoxin 1349090 trxA1 1193552 trxA1 Aquifex aeolicus VF5 thioredoxin NP_214315.1 1348671 D 224324 CDS NP_214316.1 15606935 1193553 1349003..1350040 1 NC_000918.1 hypothetical protein 1350040 1193553 aq_1917 Aquifex aeolicus VF5 hypothetical protein NP_214316.1 1349003 D 224324 CDS NP_214317.1 15606936 1193646 1350037..1351338 1 NC_000918.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1351338 engA 1193646 engA Aquifex aeolicus VF5 GTP-binding protein EngA NP_214317.1 1350037 D 224324 CDS NP_214318.1 15606937 1193647 complement(1351339..1352058) 1 NC_000918.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1352058 fliP 1193647 fliP Aquifex aeolicus VF5 flagellar biosynthesis protein FliP NP_214318.1 1351339 R 224324 CDS NP_214319.1 15606938 1193648 complement(1352290..1353285) 1 NC_000918.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-aribino-heptulonate 7-phosphate; 3-dehydroquinate synthase 1353285 1193648 aq_1922 Aquifex aeolicus VF5 3-dehydroquinate synthase NP_214319.1 1352290 R 224324 CDS NP_214320.1 15606939 1193649 1353310..1354200 1 NC_000918.1 hypothetical protein 1354200 1193649 aq_1923 Aquifex aeolicus VF5 hypothetical protein NP_214320.1 1353310 D 224324 CDS NP_214321.1 15606940 1193650 complement(1354174..1354863) 1 NC_000918.1 hypothetical protein 1354863 1193650 aq_1924 Aquifex aeolicus VF5 hypothetical protein NP_214321.1 1354174 R 224324 CDS NP_214322.1 15606941 1193651 complement(1354860..1356425) 1 NC_000918.1 N-methylhydantoinase B 1356425 hyuB 1193651 hyuB Aquifex aeolicus VF5 N-methylhydantoinase B NP_214322.1 1354860 R 224324 CDS NP_214323.1 15606942 1193652 1356932..1358149 1 NC_000918.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1358149 tufA2 1193652 tufA2 Aquifex aeolicus VF5 elongation factor Tu NP_214323.1 1356932 D 224324 CDS NP_214324.1 15606943 1193653 1358160..1358312 1 NC_000918.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 1358312 rpmG 1193653 rpmG Aquifex aeolicus VF5 50S ribosomal protein L33 NP_214324.1 1358160 D 224324 CDS NP_214325.1 15607136 1193999 1358431..1358628 1 NC_000918.1 preprotein translocase subunit SecE 1358628 secE 1193999 secE Aquifex aeolicus VF5 preprotein translocase subunit SecE NP_214325.1 1358431 D 224324 CDS NP_214326.1 15606944 1193654 1358625..1359371 1 NC_000918.1 transcription antitermination protein NusG 1359371 nusG 1193654 nusG Aquifex aeolicus VF5 transcription antitermination protein NusG NP_214326.1 1358625 D 224324 CDS NP_214327.1 15606945 1193655 1359386..1359823 1 NC_000918.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1359823 rplK 1193655 rplK Aquifex aeolicus VF5 50S ribosomal protein L11 NP_214327.1 1359386 D 224324 CDS NP_214328.1 15606946 1193656 1359828..1360556 1 NC_000918.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1360556 rplA 1193656 rplA Aquifex aeolicus VF5 50S ribosomal protein L1 NP_214328.1 1359828 D 224324 CDS NP_214329.1 15606947 1193657 1360571..1361170 1 NC_000918.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1361170 rplJ 1193657 rplJ Aquifex aeolicus VF5 50S ribosomal protein L10 NP_214329.1 1360571 D 224324 CDS NP_214330.1 15606948 1193658 1361173..1361559 1 NC_000918.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1361559 rplL 1193658 rplL Aquifex aeolicus VF5 50S ribosomal protein L7/L12 NP_214330.1 1361173 D 224324 CDS NP_214331.1 15606949 1193659 1361772..1366178 1 NC_000918.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1366178 rpoB 1193659 rpoB Aquifex aeolicus VF5 DNA-directed RNA polymerase subunit beta NP_214331.1 1361772 D 224324 CDS NP_214332.1 15606950 1193660 1366175..1370899 1 NC_000918.1 RNA polymerase subunit beta' 1370899 rpoC 1193660 rpoC Aquifex aeolicus VF5 RNA polymerase subunit beta' NP_214332.1 1366175 D 224324 CDS NP_214333.1 15606951 1193661 complement(1370896..1372578) 1 NC_000918.1 serine protease 1372578 aprV 1193661 aprV Aquifex aeolicus VF5 serine protease NP_214333.1 1370896 R 224324 CDS NP_214334.1 15606952 1193662 1372613..1373650 1 NC_000918.1 hypothetical protein 1373650 1193662 aq_1952 Aquifex aeolicus VF5 hypothetical protein NP_214334.1 1372613 D 224324 CDS NP_214335.1 15606953 1193663 complement(1373638..1374096) 1 NC_000918.1 hypothetical protein 1374096 1193663 aq_1953 Aquifex aeolicus VF5 hypothetical protein NP_214335.1 1373638 R 224324 CDS NP_214336.1 15606954 1193664 1374064..1374528 1 NC_000918.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1374528 rplS 1193664 rplS Aquifex aeolicus VF5 50S ribosomal protein L19 NP_214336.1 1374064 D 224324 CDS NP_214337.1 15606955 1193665 1374521..1375111 1 NC_000918.1 RNase HII 1375111 rnhB 1193665 rnhB Aquifex aeolicus VF5 RNase HII NP_214337.1 1374521 D 224324 CDS NP_214338.1 15606956 1193666 complement(1375108..1375890) 1 NC_000918.1 hypothetical protein 1375890 1193666 aq_1956 Aquifex aeolicus VF5 hypothetical protein NP_214338.1 1375108 R 224324 CDS NP_214339.1 15606957 1193667 complement(1376132..1377250) 1 NC_000918.1 hypothetical protein 1377250 1193667 aq_1958 Aquifex aeolicus VF5 hypothetical protein NP_214339.1 1376132 R 224324 CDS NP_214340.1 15606958 1193668 1377316..1377798 1 NC_000918.1 hypothetical protein 1377798 1193668 aq_1959 Aquifex aeolicus VF5 hypothetical protein NP_214340.1 1377316 D 224324 CDS NP_214341.1 15606959 1193669 1377795..1378562 1 NC_000918.1 HMP-P kinase 1378562 thiD 1193669 thiD Aquifex aeolicus VF5 HMP-P kinase NP_214341.1 1377795 D 224324 CDS NP_214342.1 15606960 1193670 complement(1378549..1379325) 1 NC_000918.1 flagellar biosynthetic protein FliR 1379325 fliR 1193670 fliR Aquifex aeolicus VF5 flagellar biosynthetic protein FliR NP_214342.1 1378549 R 224324 CDS NP_214343.1 15606961 1193671 complement(1379313..1379582) 1 NC_000918.1 flagellar biosynthesis protein FliQ 1379582 fliQ 1193671 fliQ Aquifex aeolicus VF5 flagellar biosynthesis protein FliQ NP_214343.1 1379313 R 224324 CDS NP_214344.1 15606962 1193672 complement(1380178..1381698) 1 NC_000918.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1381698 purH 1193672 purH Aquifex aeolicus VF5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NP_214344.1 1380178 R 224324 CDS NP_214345.1 15606963 1193673 complement(1381711..1383000) 1 NC_000918.1 hypothetical protein 1383000 1193673 aq_1964 Aquifex aeolicus VF5 hypothetical protein NP_214345.1 1381711 R 224324 CDS NP_214346.1 15606964 1193674 complement(1383000..1383404) 1 NC_000918.1 hypothetical protein 1383404 1193674 aq_1965 Aquifex aeolicus VF5 hypothetical protein NP_214346.1 1383000 R 224324 CDS NP_214347.1 15606965 1193675 complement(1383388..1383993) 1 NC_000918.1 hypothetical protein 1383993 1193675 aq_1966 Aquifex aeolicus VF5 hypothetical protein NP_214347.1 1383388 R 224324 CDS NP_214348.1 15606966 1193676 1384011..1385735 1 NC_000918.1 DNA polymerase I (PolI) 1385735 polA 1193676 polA Aquifex aeolicus VF5 DNA polymerase I (PolI) NP_214348.1 1384011 D 224324 CDS NP_214349.1 15606967 1193677 1385746..1386363 1 NC_000918.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP 1386363 hisIE 1193677 hisIE Aquifex aeolicus VF5 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP NP_214349.1 1385746 D 224324 CDS NP_214350.1 15606968 1193678 1386624..1387808 1 NC_000918.1 aspartate aminotransferase 1387808 aspC1 1193678 aspC1 Aquifex aeolicus VF5 aspartate aminotransferase NP_214350.1 1386624 D 224324 CDS NP_214351.1 15606969 1193679 complement(1387805..1389505) 1 NC_000918.1 type IV pilus assembly protein TapB 1389505 tapB 1193679 tapB Aquifex aeolicus VF5 type IV pilus assembly protein TapB NP_214351.1 1387805 R 224324 CDS NP_214352.1 15606970 1193680 complement(1389498..1390295) 1 NC_000918.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1390295 panB 1193680 panB Aquifex aeolicus VF5 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_214352.1 1389498 R 224324 CDS NP_214353.1 15606971 1193681 complement(1390299..1390643) 1 NC_000918.1 hypothetical protein 1390643 1193681 aq_1974 Aquifex aeolicus VF5 hypothetical protein NP_214353.1 1390299 R 224324 CDS NP_214354.1 15606972 1193682 1390681..1391232 1 NC_000918.1 hypothetical protein 1391232 1193682 aq_1975 Aquifex aeolicus VF5 hypothetical protein NP_214354.1 1390681 D 224324 CDS NP_214355.1 15606973 1193683 1391225..1391896 1 NC_000918.1 enolase-phosphatase E-1 1391896 masA 1193683 masA Aquifex aeolicus VF5 enolase-phosphatase E-1 NP_214355.1 1391225 D 224324 CDS NP_214356.1 15606974 1193684 1391893..1392258 1 NC_000918.1 hypothetical protein 1392258 1193684 aq_1978 Aquifex aeolicus VF5 hypothetical protein NP_214356.1 1391893 D 224324 CDS NP_214357.1 15606975 1193685 1392255..1392881 1 NC_000918.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway; methylthioribulose-1-phosphate dehydratase 1392881 fucA2 1193685 fucA2 Aquifex aeolicus VF5 methylthioribulose-1-phosphate dehydratase NP_214357.1 1392255 D 224324 CDS NP_214358.1 15606976 1193686 complement(1393228..1394154) 1 NC_000918.1 hypothetical protein 1394154 1193686 aq_1980 Aquifex aeolicus VF5 hypothetical protein NP_214358.1 1393228 R 224324 CDS NP_214359.1 15606977 1193687 1394503..1395147 1 NC_000918.1 hypothetical protein 1395147 1193687 aq_1982 Aquifex aeolicus VF5 hypothetical protein NP_214359.1 1394503 D 224324 CDS NP_214360.1 15606978 1193688 1395158..1395952 1 NC_000918.1 myo-inositol-1(or 4)-monophosphatase 1395952 imp2 1193688 imp2 Aquifex aeolicus VF5 myo-inositol-1(or 4)-monophosphatase NP_214360.1 1395158 D 224324 CDS NP_214361.1 15606979 1193689 1395949..1396539 1 NC_000918.1 hypothetical protein 1396539 1193689 aq_1985 Aquifex aeolicus VF5 hypothetical protein NP_214361.1 1395949 D 224324 CDS NP_214362.1 15606980 1193690 complement(1396523..1397248) 1 NC_000918.1 hypothetical protein 1397248 1193690 aq_1986 Aquifex aeolicus VF5 hypothetical protein NP_214362.1 1396523 R 224324 CDS NP_214363.1 15606981 1193691 complement(1397248..1397649) 1 NC_000918.1 hypothetical protein 1397649 1193691 aq_1987 Aquifex aeolicus VF5 hypothetical protein NP_214363.1 1397248 R 224324 CDS NP_214364.1 15606982 1193692 complement(1397654..1398268) 1 NC_000918.1 TolQ-like protein 1398268 tolQ 1193692 tolQ Aquifex aeolicus VF5 TolQ-like protein NP_214364.1 1397654 R 224324 CDS NP_214365.1 15606983 1193693 complement(1398272..1400833) 1 NC_000918.1 hypothetical protein 1400833 1193693 aq_1989 Aquifex aeolicus VF5 hypothetical protein NP_214365.1 1398272 R 224324 CDS NP_214366.1 15606984 1193694 complement(1400808..1401446) 1 NC_000918.1 phosphoglycerate mutase 1401446 pgmA 1193694 pgmA Aquifex aeolicus VF5 phosphoglycerate mutase NP_214366.1 1400808 R 224324 CDS NP_214367.1 15606985 1193695 complement(1401455..1402363) 1 NC_000918.1 heat shock protein X 1402363 htpX 1193695 htpX Aquifex aeolicus VF5 heat shock protein X NP_214367.1 1401455 R 224324 CDS NP_214368.1 15606986 1193696 complement(1402380..1403027) 1 NC_000918.1 hypothetical protein 1403027 1193696 aq_1993 Aquifex aeolicus VF5 hypothetical protein NP_214368.1 1402380 R 224324 CDS NP_214369.1 15606987 1193697 complement(1403011..1403916) 1 NC_000918.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1403916 era 1193697 era Aquifex aeolicus VF5 GTP-binding protein Era NP_214369.1 1403011 R 224324 CDS NP_214370.1 15606988 1193698 complement(1403979..1404668) 1 NC_000918.1 hypothetical protein 1404668 1193698 aq_1996 Aquifex aeolicus VF5 hypothetical protein NP_214370.1 1403979 R 224324 CDS NP_214371.1 15606989 1193699 1404707..1405402 1 NC_000918.1 hypothetical protein 1405402 1193699 aq_1997 Aquifex aeolicus VF5 hypothetical protein NP_214371.1 1404707 D 224324 CDS NP_214372.1 15606990 1193700 1405481..1407037 1 NC_000918.1 flagellin 1407037 fliC 1193700 fliC Aquifex aeolicus VF5 flagellin NP_214372.1 1405481 D 224324 CDS NP_214373.1 15606991 1193701 1407080..1407445 1 NC_000918.1 hypothetical protein 1407445 1193701 aq_2000 Aquifex aeolicus VF5 hypothetical protein NP_214373.1 1407080 D 224324 CDS NP_214374.1 15606992 1193702 1407448..1408773 1 NC_000918.1 flagellar hook associated protein FliD 1408773 fliD 1193702 fliD Aquifex aeolicus VF5 flagellar hook associated protein FliD NP_214374.1 1407448 D 224324 CDS NP_214375.1 15606993 1193703 1408770..1409144 1 NC_000918.1 flagellar protein FliS 1409144 fliS 1193703 fliS Aquifex aeolicus VF5 flagellar protein FliS NP_214375.1 1408770 D 224324 CDS NP_214378.1 15606996 1193706 complement(1410986..1411810) 1 NC_000918.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1411810 rpsB 1193706 rpsB Aquifex aeolicus VF5 30S ribosomal protein S2 NP_214378.1 1410986 R 224324 CDS NP_214379.1 15606997 1193707 complement(1411902..1412879) 1 NC_000918.1 hypothetical protein 1412879 1193707 aq_2009 Aquifex aeolicus VF5 hypothetical protein NP_214379.1 1411902 R 224324 CDS NP_214380.1 15606998 1193708 complement(1412896..1415712) 1 NC_000918.1 hypothetical protein 1415712 1193708 aq_2011 Aquifex aeolicus VF5 hypothetical protein NP_214380.1 1412896 R 224324 CDS NP_214381.1 15606999 1193709 1415787..1416200 1 NC_000918.1 hypothetical protein 1416200 1193709 aq_2013 Aquifex aeolicus VF5 hypothetical protein NP_214381.1 1415787 D 224324 CDS NP_214382.1 15607000 1193710 1416211..1417263 1 NC_000918.1 flagellar biosynthetic protein FlhB 1417263 flhB 1193710 flhB Aquifex aeolicus VF5 flagellar biosynthetic protein FlhB NP_214382.1 1416211 D 224324 CDS NP_214383.1 15607001 1193711 complement(1417254..1418564) 1 NC_000918.1 protoporphyrinogen oxidase 1418564 hemG 1193711 hemG Aquifex aeolicus VF5 protoporphyrinogen oxidase NP_214383.1 1417254 R 224324 CDS NP_214384.1 15607002 1193712 1419127..1420140 1 NC_000918.1 phosphate-binding periplasmic protein 1420140 pstS 1193712 pstS Aquifex aeolicus VF5 phosphate-binding periplasmic protein NP_214384.1 1419127 D 224324 CDS NP_214385.1 15607003 1193713 1420127..1421089 1 NC_000918.1 phosphate ABC transporter permease 1421089 pstC 1193713 pstC Aquifex aeolicus VF5 phosphate ABC transporter permease NP_214385.1 1420127 D 224324 CDS NP_214386.1 15607004 1193714 1421068..1421925 1 NC_000918.1 phosphate ABC transporter permease 1421925 pstA 1193714 pstA Aquifex aeolicus VF5 phosphate ABC transporter permease NP_214386.1 1421068 D 224324 CDS NP_214387.1 15607005 1193715 1421693..1422364 1 NC_000918.1 hypothetical protein 1422364 1193715 aq_2020 Aquifex aeolicus VF5 hypothetical protein NP_214387.1 1421693 D 224324 CDS NP_214388.1 15607006 1193716 1422407..1423621 1 NC_000918.1 TldD protein 1423621 tldD 1193716 tldD Aquifex aeolicus VF5 TldD protein NP_214388.1 1422407 D 224324 CDS NP_214389.1 15607007 1193717 1424165..1425637 1 NC_000918.1 inosine monophosphate dehydrogenase 1425637 guaB 1193717 guaB Aquifex aeolicus VF5 inosine monophosphate dehydrogenase NP_214389.1 1424165 D 224324 CDS NP_214390.1 15607008 1193718 complement(1425634..1426728) 1 NC_000918.1 hypothetical protein 1426728 1193718 aq_2027 Aquifex aeolicus VF5 hypothetical protein NP_214390.1 1425634 R 224324 CDS NP_214391.1 15607009 1193719 1426749..1427258 1 NC_000918.1 hypothetical protein 1427258 1193719 aq_2028 Aquifex aeolicus VF5 hypothetical protein NP_214391.1 1426749 D 224324 CDS NP_214392.1 15607010 1193720 1427260..1428528 1 NC_000918.1 Na(+)/H(+) antiporter 1428528 napA3 1193720 napA3 Aquifex aeolicus VF5 Na(+)/H(+) antiporter NP_214392.1 1427260 D 224324 CDS NP_214394.1 15607012 1193722 1429084..1431501 1 NC_000918.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1431501 infB 1193722 infB Aquifex aeolicus VF5 translation initiation factor IF-2 NP_214394.1 1429084 D 224324 CDS NP_214395.1 15607013 1193723 1431465..1432124 1 NC_000918.1 hypothetical protein 1432124 1193723 aq_2035 Aquifex aeolicus VF5 hypothetical protein NP_214395.1 1431465 D 224324 CDS NP_214396.1 15607014 1193724 1432121..1432771 1 NC_000918.1 hypothetical protein 1432771 1193724 aq_2036 Aquifex aeolicus VF5 hypothetical protein NP_214396.1 1432121 D 224324 CDS NP_214397.1 15607015 1193725 complement(1432768..1434204) 1 NC_000918.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1434204 atpD 1193725 atpD Aquifex aeolicus VF5 F0F1 ATP synthase subunit beta NP_214397.1 1432768 R 224324 CDS NP_214398.1 15607016 1193726 complement(1434218..1435093) 1 NC_000918.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1435093 atpG1 1193726 atpG1 Aquifex aeolicus VF5 F0F1 ATP synthase subunit gamma NP_214398.1 1434218 R 224324 CDS NP_214399.1 15607017 1193727 1435164..1435613 1 NC_000918.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1435613 rplI 1193727 rplI Aquifex aeolicus VF5 50S ribosomal protein L9 NP_214399.1 1435164 D 224324 CDS NP_214400.1 15607018 1193728 1435623..1436561 1 NC_000918.1 cytochrome C biogenesis protein 1436561 hemX2 1193728 hemX2 Aquifex aeolicus VF5 cytochrome C biogenesis protein NP_214400.1 1435623 D 224324 CDS NP_214401.1 15607019 1193729 complement(1436551..1437729) 1 NC_000918.1 hypothetical protein 1437729 1193729 aq_2044 Aquifex aeolicus VF5 hypothetical protein NP_214401.1 1436551 R 224324 CDS NP_214402.1 15607020 1193730 complement(1437734..1438966) 1 NC_000918.1 folylpolyglutamate synthetase 1438966 folC 1193730 folC Aquifex aeolicus VF5 folylpolyglutamate synthetase NP_214402.1 1437734 R 224324 CDS NP_214403.1 15607021 1193731 1438996..1441113 1 NC_000918.1 VacB/RNase II family 3'-5' exoribonuclease 1441113 vacB 1193731 vacB Aquifex aeolicus VF5 VacB/RNase II family 3'-5' exoribonuclease NP_214403.1 1438996 D 224324 CDS NP_214404.1 15607022 1193732 1441129..1441695 1 NC_000918.1 hypothetical protein 1441695 1193732 aq_2049 Aquifex aeolicus VF5 hypothetical protein NP_214404.1 1441129 D 224324 CDS NP_214405.1 15607023 1193733 1441695..1442420 1 NC_000918.1 flagellar hook basal-body protein FlgG 1442420 flgG1 1193733 flgG1 Aquifex aeolicus VF5 flagellar hook basal-body protein FlgG NP_214405.1 1441695 D 224324 CDS NP_214406.1 15607024 1193734 complement(1442417..1444795) 1 NC_000918.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1444795 recG 1193734 recG Aquifex aeolicus VF5 ATP-dependent DNA helicase RecG NP_214406.1 1442417 R 224324 CDS NP_214407.1 15607025 1193735 complement(1444797..1448147) 1 NC_000918.1 hypothetical protein 1448147 1193735 aq_2054 Aquifex aeolicus VF5 hypothetical protein NP_214407.1 1444797 R 224324 CDS NP_214408.1 15607026 1193736 complement(1448156..1448791) 1 NC_000918.1 hypothetical protein 1448791 1193736 aq_2056 Aquifex aeolicus VF5 hypothetical protein NP_214408.1 1448156 R 224324 CDS NP_214409.1 15607027 1193737 complement(1448818..1450410) 1 NC_000918.1 DNA helicase 1450410 helX 1193737 helX Aquifex aeolicus VF5 DNA helicase NP_214409.1 1448818 R 224324 CDS NP_214410.1 15607028 1193830 1450301..1450936 1 NC_000918.1 2-acylglycerophosphoethanolamine acyltransferase 1450936 aas 1193830 aas Aquifex aeolicus VF5 2-acylglycerophosphoethanolamine acyltransferase NP_214410.1 1450301 D 224324 CDS NP_214411.1 15607029 1193831 complement(1450915..1451556) 1 NC_000918.1 hypothetical protein 1451556 1193831 aq_2059 Aquifex aeolicus VF5 hypothetical protein NP_214411.1 1450915 R 224324 CDS NP_214412.1 15607030 1193832 complement(1451540..1452904) 1 NC_000918.1 hypothetical protein 1452904 1193832 aq_2060 Aquifex aeolicus VF5 hypothetical protein NP_214412.1 1451540 R 224324 CDS NP_214413.1 15607031 1193833 complement(1453189..1453548) 1 NC_000918.1 hypothetical protein 1453548 1193833 aq_2063 Aquifex aeolicus VF5 hypothetical protein NP_214413.1 1453189 R 224324 CDS NP_214414.1 15607032 1193834 complement(1453545..1454975) 1 NC_000918.1 glutamate synthase small subunit GltD 1454975 gltD 1193834 gltD Aquifex aeolicus VF5 glutamate synthase small subunit GltD NP_214414.1 1453545 R 224324 CDS NP_214415.1 15607033 1193835 1455015..1455485 1 NC_000918.1 hypothetical protein 1455485 1193835 aq_2066 Aquifex aeolicus VF5 hypothetical protein NP_214415.1 1455015 D 224324 CDS NP_214416.2 566344043 1193836 1455497..1455835 1 NC_000918.1 hypothetical protein 1455835 1193836 aq_2067 Aquifex aeolicus VF5 hypothetical protein NP_214416.2 1455497 D 224324 CDS NP_214417.1 15607035 1193837 1455909..1456727 1 NC_000918.1 acetylglutamate kinase 1456727 argB 1193837 argB Aquifex aeolicus VF5 acetylglutamate kinase NP_214417.1 1455909 D 224324 CDS NP_214418.1 15607036 1193838 1456740..1457771 1 NC_000918.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1457771 obgE 1193838 obgE Aquifex aeolicus VF5 GTPase ObgE NP_214418.1 1456740 D 224324 CDS NP_214419.1 15607037 1193839 1457797..1458972 1 NC_000918.1 hypothetical protein 1458972 1193839 aq_2071 Aquifex aeolicus VF5 hypothetical protein NP_214419.1 1457797 D 224324 CDS NP_214420.1 15607038 1193840 1458969..1460126 1 NC_000918.1 hypothetical protein 1460126 1193840 aq_2073 Aquifex aeolicus VF5 hypothetical protein NP_214420.1 1458969 D 224324 CDS NP_214421.1 15607039 1193841 1460123..1461370 1 NC_000918.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase 1461370 murD 1193841 murD Aquifex aeolicus VF5 UDP-N-acetylmuramoylalanine-D-glutamate ligase NP_214421.1 1460123 D 224324 CDS NP_214422.1 15607040 1193842 complement(1461357..1461971) 1 NC_000918.1 phosphoribosyl anthranilate isomerase 1461971 trpF 1193842 trpF Aquifex aeolicus VF5 phosphoribosyl anthranilate isomerase NP_214422.1 1461357 R 224324 CDS NP_214423.1 15607041 1193843 1461990..1463531 1 NC_000918.1 SNF family Na(+)/neurotransmitter symporter 1463531 snf 1193843 snf Aquifex aeolicus VF5 SNF family Na(+)/neurotransmitter symporter NP_214423.1 1461990 D 224324 CDS NP_214424.1 15607042 1193844 1463518..1464369 1 NC_000918.1 proteinase IV 1464369 sppA 1193844 sppA Aquifex aeolicus VF5 proteinase IV NP_214424.1 1463518 D 224324 CDS NP_214425.1 15607043 1193845 1464647..1466260 1 NC_000918.1 hypothetical protein 1466260 1193845 aq_2082 Aquifex aeolicus VF5 hypothetical protein NP_214425.1 1464647 D 224324 CDS NP_214426.1 15607044 1193846 complement(1466246..1467310) 1 NC_000918.1 histidinol-phosphate aminotransferase 1467310 hisC 1193846 hisC Aquifex aeolicus VF5 histidinol-phosphate aminotransferase NP_214426.1 1466246 R 224324 CDS NP_214427.1 15607045 1193847 complement(1467575..1468078) 1 NC_000918.1 hypothetical protein 1468078 1193847 aq_2085 Aquifex aeolicus VF5 hypothetical protein NP_214427.1 1467575 R 224324 CDS NP_214428.1 15607046 1193848 complement(1468059..1468415) 1 NC_000918.1 hypothetical protein 1468415 1193848 aq_2086 Aquifex aeolicus VF5 hypothetical protein NP_214428.1 1468059 R 224324 CDS NP_214429.1 15607047 1193849 complement(1468412..1468963) 1 NC_000918.1 hypothetical protein 1468963 1193849 aq_2087 Aquifex aeolicus VF5 hypothetical protein NP_214429.1 1468412 R 224324 CDS NP_214430.1 15607048 1193850 1468992..1469498 1 NC_000918.1 hypothetical protein 1469498 1193850 aq_2088 Aquifex aeolicus VF5 hypothetical protein NP_214430.1 1468992 D 224324 CDS NP_214431.1 15607049 1193851 1469552..1471126 1 NC_000918.1 2-isopropylmalate synthase 1471126 leuA2 1193851 leuA2 Aquifex aeolicus VF5 2-isopropylmalate synthase NP_214431.1 1469552 D 224324 CDS NP_214432.1 15607050 1193852 1471392..1472108 1 NC_000918.1 thiol:disulfide interchange protein 1472108 dsbC 1193852 dsbC Aquifex aeolicus VF5 thiol:disulfide interchange protein NP_214432.1 1471392 D 224324 CDS NP_214433.1 15607051 1193853 complement(1472329..1473573) 1 NC_000918.1 aminotransferase 1473573 aspC2 1193853 aspC2 Aquifex aeolicus VF5 aminotransferase NP_214433.1 1472329 R 224324 CDS NP_214434.1 15607052 1193854 complement(1473566..1473928) 1 NC_000918.1 dnaK suppressor protein 1473928 dksA 1193854 dksA Aquifex aeolicus VF5 dnaK suppressor protein NP_214434.1 1473566 R 224324 CDS NP_214435.1 15607053 1193855 complement(1473947..1474504) 1 NC_000918.1 flavodoxin 1474504 floX 1193855 floX Aquifex aeolicus VF5 flavodoxin NP_214435.1 1473947 R 224324 CDS NP_214436.1 15607054 1193856 complement(1474521..1475360) 1 NC_000918.1 hypothetical protein 1475360 1193856 aq_2098 Aquifex aeolicus VF5 hypothetical protein NP_214436.1 1474521 R 224324 CDS NP_214437.1 15607055 1193857 complement(1475353..1476834) 1 NC_000918.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1476834 pepA 1193857 pepA Aquifex aeolicus VF5 leucyl aminopeptidase NP_214437.1 1475353 R 224324 CDS NP_214438.1 15607056 1193858 1476861..1478534 1 NC_000918.1 carbamoyl-phosphate synthase large subunit 1478534 carB2 1193858 carB2 Aquifex aeolicus VF5 carbamoyl-phosphate synthase large subunit NP_214438.1 1476861 D 224324 CDS NP_214439.1 15607057 1193859 1478521..1479258 1 NC_000918.1 50S ribosomal protein L11 methyltransferase 1479258 prmA 1193859 prmA Aquifex aeolicus VF5 50S ribosomal protein L11 methyltransferase NP_214439.1 1478521 D 224324 CDS NP_214443.1 15607061 1193863 1483320..1485179 1 NC_000918.1 hypothetical protein 1485179 1193863 aq_2107 Aquifex aeolicus VF5 hypothetical protein NP_214443.1 1483320 D 224324 CDS NP_214444.1 15607062 1193864 1485176..1485808 1 NC_000918.1 hypothetical protein 1485808 1193864 aq_2108 Aquifex aeolicus VF5 hypothetical protein NP_214444.1 1485176 D 224324 CDS NP_214445.1 15607063 1193865 1485819..1486811 1 NC_000918.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1486811 hemB 1193865 hemB Aquifex aeolicus VF5 delta-aminolevulinic acid dehydratase NP_214445.1 1485819 D 224324 CDS NP_214446.1 15607064 1193866 1486808..1487740 1 NC_000918.1 acetoin utilization protein 1487740 acuC2 1193866 acuC2 Aquifex aeolicus VF5 acetoin utilization protein NP_214446.1 1486808 D 224324 CDS NP_214447.1 15607065 1193867 1488032..1488808 1 NC_000918.1 hypothetical protein 1488808 1193867 aq_2113 Aquifex aeolicus VF5 hypothetical protein NP_214447.1 1488032 D 224324 CDS NP_214448.1 15607066 1193868 complement(1488786..1490156) 1 NC_000918.1 initiation factor eIF-2B subunit alpha 1490156 eif 1193868 eif Aquifex aeolicus VF5 initiation factor eIF-2B subunit alpha NP_214448.1 1488786 R 224324 CDS NP_214449.1 15607067 1193869 complement(1490168..1491274) 1 NC_000918.1 glucosyl transferase I 1491274 rfaG 1193869 rfaG Aquifex aeolicus VF5 glucosyl transferase I NP_214449.1 1490168 R 224324 CDS NP_214450.1 15607068 1193870 complement(1491677..1492327) 1 NC_000918.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1492327 purC 1193870 purC Aquifex aeolicus VF5 phosphoribosylaminoimidazole-succinocarboxamide synthase NP_214450.1 1491677 R 224324 CDS NP_214451.1 15607069 1193871 complement(1492324..1492845) 1 NC_000918.1 hypothetical protein 1492845 1193871 aq_2118 Aquifex aeolicus VF5 hypothetical protein NP_214451.1 1492324 R 224324 CDS NP_214452.1 15607070 1193872 complement(1492805..1493725) 1 NC_000918.1 thiamine monophosphate kinase 1493725 thiL 1193872 thiL Aquifex aeolicus VF5 thiamine monophosphate kinase NP_214452.1 1492805 R 224324 CDS NP_214453.1 15607071 1193873 complement(1493722..1494990) 1 NC_000918.1 hemolysin homolog protein 1494990 hlyC 1193873 hlyC Aquifex aeolicus VF5 hemolysin homolog protein NP_214453.1 1493722 R 224324 CDS NP_214454.1 15607072 1193874 complement(1494959..1495876) 1 NC_000918.1 ABC transporter 1495876 abcT11 1193874 abcT11 Aquifex aeolicus VF5 ABC transporter NP_214454.1 1494959 R 224324 CDS NP_214455.1 15607073 1193875 complement(1495878..1497248) 1 NC_000918.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1497248 hemN 1193875 hemN Aquifex aeolicus VF5 coproporphyrinogen III oxidase NP_214455.1 1495878 R 224324 CDS NP_214456.1 15607074 1193876 1497725..1499425 1 NC_000918.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1499425 uvrC 1193876 uvrC Aquifex aeolicus VF5 excinuclease ABC subunit C NP_214456.1 1497725 D 224324 CDS NP_214457.1 15607075 1193877 1499413..1499835 1 NC_000918.1 hypothetical protein 1499835 1193877 aq_2128 Aquifex aeolicus VF5 hypothetical protein NP_214457.1 1499413 D 224324 CDS NP_214458.1 15607076 1193878 complement(1500045..1500938) 1 NC_000918.1 sodium bile acid symporter family Na(+) dependent transporter 1500938 sbf 1193878 sbf Aquifex aeolicus VF5 sodium bile acid symporter family Na(+) dependent transporter NP_214458.1 1500045 R 224324 CDS NP_214459.1 15607077 1193879 complement(1501407..1502318) 1 NC_000918.1 methionyl-tRNA formyltransferase 1502318 fmt 1193879 fmt Aquifex aeolicus VF5 methionyl-tRNA formyltransferase NP_214459.1 1501407 R 224324 CDS NP_214460.1 15607078 1193880 complement(1502315..1503163) 1 NC_000918.1 pantothenate synthetase 1503163 panC 1193880 panC Aquifex aeolicus VF5 pantothenate synthetase NP_214460.1 1502315 R 224324 CDS NP_214461.1 15607079 1193881 1503157..1503528 1 NC_000918.1 hypothetical protein 1503528 1193881 aq_2134 Aquifex aeolicus VF5 hypothetical protein NP_214461.1 1503157 D 224324 CDS NP_214462.1 15607080 1193882 1503518..1504153 1 NC_000918.1 hypothetical protein 1504153 1193882 aq_2135 Aquifex aeolicus VF5 hypothetical protein NP_214462.1 1503518 D 224324 CDS NP_214463.1 15607081 1193883 1504146..1504907 1 NC_000918.1 ABC transporter 1504907 abcT12 1193883 abcT12 Aquifex aeolicus VF5 ABC transporter NP_214463.1 1504146 D 224324 CDS NP_214464.1 15607082 1193884 1504917..1505540 1 NC_000918.1 hypothetical protein 1505540 1193884 aq_2138 Aquifex aeolicus VF5 hypothetical protein NP_214464.1 1504917 D 224324 CDS NP_214465.1 15607083 1193885 1505500..1506153 1 NC_000918.1 hypothetical protein 1506153 1193885 aq_2139 Aquifex aeolicus VF5 hypothetical protein NP_214465.1 1505500 D 224324 CDS NP_214466.1 15607084 1193886 complement(1506134..1506439) 1 NC_000918.1 hypothetical protein 1506439 1193886 aq_2140 Aquifex aeolicus VF5 hypothetical protein NP_214466.1 1506134 R 224324 CDS NP_214467.1 15607085 1193887 1506462..1508456 1 NC_000918.1 glycyl-tRNA synthetase subunit beta 1508456 glyS 1193887 glyS Aquifex aeolicus VF5 glycyl-tRNA synthetase subunit beta NP_214467.1 1506462 D 224324 CDS NP_214468.1 15607086 1193888 1508458..1511028 1 NC_000918.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1511028 ppsA 1193888 ppsA Aquifex aeolicus VF5 phosphoenolpyruvate synthase NP_214468.1 1508458 D 224324 CDS NP_214469.1 15607087 1193889 1511025..1511921 1 NC_000918.1 hypothetical protein 1511921 1193889 aq_2144 Aquifex aeolicus VF5 hypothetical protein NP_214469.1 1511025 D 224324 CDS NP_214470.1 15607088 1193890 1511921..1512571 1 NC_000918.1 hypothetical protein 1512571 1193890 aq_2145 Aquifex aeolicus VF5 hypothetical protein NP_214470.1 1511921 D 224324 CDS NP_214471.1 15607089 1193891 1512591..1514669 1 NC_000918.1 hypothetical protein 1514669 1193891 aq_2146 Aquifex aeolicus VF5 hypothetical protein NP_214471.1 1512591 D 224324 CDS NP_214472.1 15607090 1193892 complement(1514666..1515277) 1 NC_000918.1 peptidoglycan associated lipoprotein 1515277 pal 1193892 pal Aquifex aeolicus VF5 peptidoglycan associated lipoprotein NP_214472.1 1514666 R 224324 CDS NP_214473.1 15607091 1193893 1515575..1515859 1 NC_000918.1 glutamyl-tRNA (Gln) amidotransferase subunit C 1515859 gatC 1193893 gatC Aquifex aeolicus VF5 glutamyl-tRNA (Gln) amidotransferase subunit C NP_214473.1 1515575 D 224324 CDS NP_214474.1 15607092 1193894 1515870..1516907 1 NC_000918.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1516907 recA 1193894 recA Aquifex aeolicus VF5 recombinase A NP_214474.1 1515870 D 224324 CDS NP_214475.1 15607093 1193895 1516861..1517973 1 NC_000918.1 twitching mobility protein 1517973 pilU 1193895 pilU Aquifex aeolicus VF5 twitching mobility protein NP_214475.1 1516861 D 224324 CDS NP_214476.1 15607094 1193896 1517970..1518638 1 NC_000918.1 cytidylate kinase 1518638 cmk 1193896 cmk Aquifex aeolicus VF5 cytidylate kinase NP_214476.1 1517970 D 224324 CDS NP_214477.1 15607095 1193897 1518607..1519143 1 NC_000918.1 phosphotidylglycerophosphate synthase 1519143 pgsA1 1193897 pgsA1 Aquifex aeolicus VF5 phosphotidylglycerophosphate synthase NP_214477.1 1518607 D 224324 CDS NP_214478.1 15607096 1193898 1519140..1520756 1 NC_000918.1 ssDNA-specific exonuclease RecJ 1520756 recJ 1193898 recJ Aquifex aeolicus VF5 ssDNA-specific exonuclease RecJ NP_214478.1 1519140 D 224324 CDS NP_214479.1 15607097 1193899 1520800..1521225 1 NC_000918.1 hypothetical protein 1521225 1193899 aq_2157 Aquifex aeolicus VF5 hypothetical protein NP_214479.1 1520800 D 224324 CDS NP_214480.1 15607098 1193900 complement(1521202..1522740) 1 NC_000918.1 poly A polymerase 1522740 pcnB2 1193900 pcnB2 Aquifex aeolicus VF5 poly A polymerase NP_214480.1 1521202 R 224324 CDS NP_214481.1 15607099 1193901 1522790..1523365 1 NC_000918.1 hypothetical protein 1523365 1193901 aq_2159 Aquifex aeolicus VF5 hypothetical protein NP_214481.1 1522790 D 224324 CDS NP_214482.1 15607100 1193902 1523352..1524107 1 NC_000918.1 ABC transporter 1524107 abcT9 1193902 abcT9 Aquifex aeolicus VF5 ABC transporter NP_214482.1 1523352 D 224324 CDS NP_214483.1 15607101 1193903 1524118..1524744 1 NC_000918.1 uracil phosphoribosyltransferase 1524744 uraP 1193903 uraP Aquifex aeolicus VF5 uracil phosphoribosyltransferase NP_214483.1 1524118 D 224324 CDS NP_214484.1 15607102 1193904 complement(1524721..1525290) 1 NC_000918.1 hypothetical protein 1525290 1193904 aq_2164 Aquifex aeolicus VF5 hypothetical protein NP_214484.1 1524721 R 224324 CDS NP_214485.1 15607103 1193905 complement(1525297..1526034) 1 NC_000918.1 hypothetical protein 1526034 1193905 aq_2165 Aquifex aeolicus VF5 hypothetical protein NP_214485.1 1525297 R 224324 CDS NP_214486.1 15607104 1193906 complement(1526027..1526899) 1 NC_000918.1 adhesion protein 1526899 scbA 1193906 scbA Aquifex aeolicus VF5 adhesion protein NP_214486.1 1526027 R 224324 CDS NP_214487.1 15607105 1193907 complement(1526912..1528321) 1 NC_000918.1 hypothetical protein 1528321 1193907 aq_2168 Aquifex aeolicus VF5 hypothetical protein NP_214487.1 1526912 R 224324 CDS NP_214488.1 15607106 1193908 1528662..1529381 1 NC_000918.1 hypothetical protein 1529381 1193908 aq_2170 Aquifex aeolicus VF5 hypothetical protein NP_214488.1 1528662 D 224324 CDS NP_214489.1 15607107 1193909 1529365..1529856 1 NC_000918.1 hypothetical protein 1529856 1193909 aq_2171 Aquifex aeolicus VF5 hypothetical protein NP_214489.1 1529365 D 224324 CDS NP_214490.1 15607108 1193910 1529849..1530346 1 NC_000918.1 hypothetical protein 1530346 1193910 aq_2172 Aquifex aeolicus VF5 hypothetical protein NP_214490.1 1529849 D 224324 CDS NP_214491.1 15607109 1193911 1530315..1530749 1 NC_000918.1 hypothetical protein 1530749 1193911 aq_2173 Aquifex aeolicus VF5 hypothetical protein NP_214491.1 1530315 D 224324 CDS NP_214492.1 15607110 1193912 1530746..1531048 1 NC_000918.1 integration host factor subunit beta 1531048 ihfB 1193912 ihfB Aquifex aeolicus VF5 integration host factor subunit beta NP_214492.1 1530746 D 224324 CDS NP_214493.1 15607111 1193913 1531150..1532115 1 NC_000918.1 hypothetical protein 1532115 1193913 aq_2175 Aquifex aeolicus VF5 hypothetical protein NP_214493.1 1531150 D 224324 CDS NP_214494.1 15607112 1193914 1532112..1532618 1 NC_000918.1 shikimate kinase 1532618 aroK 1193914 aroK Aquifex aeolicus VF5 shikimate kinase NP_214494.1 1532112 D 224324 CDS NP_214495.1 15607113 1193915 complement(1532586..1533389) 1 NC_000918.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 1533389 thiG 1193915 thiG Aquifex aeolicus VF5 thiazole synthase NP_214495.1 1532586 R 224324 CDS YP_008920738.1 566344058 17925357 complement(1533411..1533620) 1 NC_000918.1 sulfur carrier protein ThiS 1533620 17925357 aq_2178a Aquifex aeolicus VF5 sulfur carrier protein ThiS YP_008920738.1 1533411 R 224324 CDS NP_214496.1 15607114 1193916 1533662..1534240 1 NC_000918.1 TetR/AcrR family transcriptional regulator 1534240 acrR2 1193916 acrR2 Aquifex aeolicus VF5 TetR/AcrR family transcriptional regulator NP_214496.1 1533662 D 224324 CDS NP_214497.1 15607115 1193917 1534286..1534750 1 NC_000918.1 molybdopterin converting factor subunit 2 1534750 moaE 1193917 moaE Aquifex aeolicus VF5 molybdopterin converting factor subunit 2 NP_214497.1 1534286 D 224324 CDS NP_214498.1 15607116 1193918 1534728..1535690 1 NC_000918.1 molybdenum cofactor biosynthesis protein A 1535690 moaA 1193918 moaA Aquifex aeolicus VF5 molybdenum cofactor biosynthesis protein A NP_214498.1 1534728 D 224324 CDS NP_214499.1 15607117 1193919 complement(1535687..1536265) 1 NC_000918.1 hypothetical protein 1536265 1193919 aq_2185 Aquifex aeolicus VF5 hypothetical protein NP_214499.1 1535687 R 224324 CDS NP_214500.1 15607118 1193920 complement(1536349..1537641) 1 NC_000918.1 sulfide-quinone reductase 1537641 sqr 1193920 sqr Aquifex aeolicus VF5 sulfide-quinone reductase NP_214500.1 1536349 R 224324 CDS NP_214501.1 15607119 1193921 1537820..1538596 1 NC_000918.1 cytochrome C oxidase subunit III 1538596 coxC 1193921 coxC Aquifex aeolicus VF5 cytochrome C oxidase subunit III NP_214501.1 1537820 D 224324 CDS NP_214502.1 15607120 1193983 1538598..1539395 1 NC_000918.1 hypothetical protein 1539395 1193983 aq_2189 Aquifex aeolicus VF5 hypothetical protein NP_214502.1 1538598 D 224324 CDS NP_214503.1 15607121 1193984 1539398..1540108 1 NC_000918.1 cytochrome C oxidase subunit II 1540108 coxB 1193984 coxB Aquifex aeolicus VF5 cytochrome C oxidase subunit II NP_214503.1 1539398 D 224324 CDS NP_214506.1 15607124 1193987 1542541..1544319 1 NC_000918.1 cytochrome C oxidase subunit I 1544319 coxA2 1193987 coxA2 Aquifex aeolicus VF5 cytochrome C oxidase subunit I NP_214506.1 1542541 D 224324 CDS NP_214507.1 15607125 1193988 1544316..1545014 1 NC_000918.1 hypothetical protein 1545014 1193988 aq_2194 Aquifex aeolicus VF5 hypothetical protein NP_214507.1 1544316 D 224324 CDS NP_214508.1 15607126 1193989 complement(1544990..1545760) 1 NC_000918.1 undecaprenol kinase 1545760 bacA 1193989 bacA Aquifex aeolicus VF5 undecaprenol kinase NP_214508.1 1544990 R 224324 CDS NP_214509.1 15607127 1193990 complement(1545764..1546519) 1 NC_000918.1 hypothetical protein 1546519 1193990 aq_2196 Aquifex aeolicus VF5 hypothetical protein NP_214509.1 1545764 R 224324 CDS NP_214510.1 15607128 1193991 complement(1546519..1547007) 1 NC_000918.1 hypothetical protein 1547007 1193991 aq_2197 Aquifex aeolicus VF5 hypothetical protein NP_214510.1 1546519 R 224324 CDS NP_214511.1 15607129 1193992 1547212..1547580 1 NC_000918.1 hypothetical protein 1547580 mopB 1193992 mopB Aquifex aeolicus VF5 hypothetical protein NP_214511.1 1547212 D 224324 CDS NP_214512.1 15607130 1193993 1547532..1549169 1 NC_000918.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1549169 groEL 1193993 groEL Aquifex aeolicus VF5 chaperonin GroEL NP_214512.1 1547532 D 224324 CDS NP_214513.1 15607131 1193994 complement(1549193..1549831) 1 NC_000918.1 hypothetical protein 1549831 1193994 aq_2203 Aquifex aeolicus VF5 hypothetical protein NP_214513.1 1549193 R 224324 CDS NP_214514.1 15607132 1193995 complement(1549833..1551092) 1 NC_000918.1 processing protease 1551092 ymxG 1193995 ymxG Aquifex aeolicus VF5 processing protease NP_214514.1 1549833 R 224324 CDS NP_046399.1 10957043 1192451 1140..1574 1 NC_001880.1 hypothetical protein 1574 1192451 aq_aa03 Aquifex aeolicus VF5 hypothetical protein NP_046399.1 1140 D 224324 CDS NP_046400.1 10957044 1192452 1711..2235 1 NC_001880.1 hypothetical protein 2235 1192452 aq_aa04 Aquifex aeolicus VF5 hypothetical protein NP_046400.1 1711 D 224324 CDS NP_046401.1 10957045 1192453 2254..3174 1 NC_001880.1 hypothetical protein 3174 1192453 aq_aa05 Aquifex aeolicus VF5 hypothetical protein NP_046401.1 2254 D 224324 CDS NP_046402.1 10957046 1192454 4111..5064 1 NC_001880.1 hypothetical protein 5064 1192454 aq_aa07 Aquifex aeolicus VF5 hypothetical protein NP_046402.1 4111 D 224324 CDS NP_046403.1 10957047 1192455 5877..6824 1 NC_001880.1 integrase protein 6824 1192455 aq_aa09 Aquifex aeolicus VF5 integrase protein NP_046403.1 5877 D 224324 CDS NP_046404.1 10957048 1192456 7395..7979 1 NC_001880.1 hypothetical protein 7979 1192456 aq_aa10 Aquifex aeolicus VF5 hypothetical protein NP_046404.1 7395 D 224324 CDS NP_046405.1 10957049 1192457 8785..9741 1 NC_001880.1 hypothetical protein 9741 1192457 aq_aa11 Aquifex aeolicus VF5 hypothetical protein NP_046405.1 8785 D 224324 CDS NP_046407.1 10957051 1192459 complement(11078..11410) 1 NC_001880.1 hypothetical protein 11410 1192459 aq_aa15 Aquifex aeolicus VF5 hypothetical protein NP_046407.1 11078 R 224324 CDS NP_046408.1 10957052 1192460 11814..12860 1 NC_001880.1 hypothetical protein 12860 1192460 aq_aa17 Aquifex aeolicus VF5 hypothetical protein NP_046408.1 11814 D 224324 CDS NP_046409.1 10957053 1192461 complement(12951..13616) 1 NC_001880.1 hypothetical protein 13616 1192461 aq_aa18 Aquifex aeolicus VF5 hypothetical protein NP_046409.1 12951 R 224324 CDS NP_046410.1 10957054 1192462 complement(15620..15958) 1 NC_001880.1 hypothetical protein 15958 1192462 aq_aa19 Aquifex aeolicus VF5 hypothetical protein NP_046410.1 15620 R 224324 CDS NP_046411.1 10957055 1192463 complement(16475..17431) 1 NC_001880.1 hypothetical protein 17431 1192463 aq_aa20 Aquifex aeolicus VF5 hypothetical protein NP_046411.1 16475 R 224324 CDS NP_046412.1 10957056 1192464 17567..18208 1 NC_001880.1 hypothetical protein 18208 1192464 aq_aa21 Aquifex aeolicus VF5 hypothetical protein NP_046412.1 17567 D 224324 CDS NP_046413.1 10957057 1192465 18282..18800 1 NC_001880.1 hypothetical protein 18800 1192465 aq_aa22 Aquifex aeolicus VF5 hypothetical protein NP_046413.1 18282 D 224324 CDS NP_046414.1 10957058 1192466 18855..19670 1 NC_001880.1 hypothetical protein 19670 1192466 aq_aa23 Aquifex aeolicus VF5 hypothetical protein NP_046414.1 18855 D 224324 CDS NP_046415.1 10957059 1192467 complement(19683..20048) 1 NC_001880.1 hypothetical protein 20048 1192467 aq_aa24 Aquifex aeolicus VF5 hypothetical protein NP_046415.1 19683 R 224324 CDS NP_046416.1 10957060 1192468 complement(21713..22333) 1 NC_001880.1 hypothetical protein 22333 1192468 aq_aa25 Aquifex aeolicus VF5 hypothetical protein NP_046416.1 21713 R 224324 CDS NP_046417.1 10957061 1192469 complement(24247..24828) 1 NC_001880.1 hypothetical protein 24828 1192469 aq_aa26 Aquifex aeolicus VF5 hypothetical protein NP_046417.1 24247 R 224324 CDS NP_046418.1 10957062 1192470 complement(24782..25561) 1 NC_001880.1 hypothetical protein 25561 1192470 aq_aa27 Aquifex aeolicus VF5 hypothetical protein NP_046418.1 24782 R 224324 CDS NP_046419.1 10957063 1192471 complement(25741..26196) 1 NC_001880.1 hypothetical protein 26196 1192471 aq_aa28 Aquifex aeolicus VF5 hypothetical protein NP_046419.1 25741 R 224324 CDS NP_046420.1 10957064 1192472 complement(26335..27105) 1 NC_001880.1 hypothetical protein 27105 1192472 aq_aa29 Aquifex aeolicus VF5 hypothetical protein NP_046420.1 26335 R 224324 CDS NP_046421.1 10957065 1192473 complement(27142..27954) 1 NC_001880.1 hypothetical protein 27954 1192473 aq_aa31 Aquifex aeolicus VF5 hypothetical protein NP_046421.1 27142 R 224324 CDS NP_046422.1 10957066 1192474 complement(28405..28995) 1 NC_001880.1 hypothetical protein 28995 1192474 aq_aa32 Aquifex aeolicus VF5 hypothetical protein NP_046422.1 28405 R 224324 CDS NP_046423.1 10957067 1192475 30009..30965 1 NC_001880.1 hypothetical protein 30965 1192475 aq_aa34 Aquifex aeolicus VF5 hypothetical protein NP_046423.1 30009 D 224324 CDS NP_046424.1 10957068 1192476 complement(31205..31846) 1 NC_001880.1 hypothetical protein 31846 1192476 aq_aa35 Aquifex aeolicus VF5 hypothetical protein NP_046424.1 31205 R 224324 CDS NP_046425.1 10957069 1192477 33210..33650 1 NC_001880.1 hypothetical protein 33650 1192477 aq_aa37 Aquifex aeolicus VF5 hypothetical protein NP_046425.1 33210 D 224324 CDS NP_046426.1 10957070 1192478 33892..34854 1 NC_001880.1 hypothetical protein 34854 1192478 aq_aa38 Aquifex aeolicus VF5 hypothetical protein NP_046426.1 33892 D 224324 CDS NP_046427.1 10957071 1192479 complement(35238..35933) 1 NC_001880.1 hypothetical protein 35933 1192479 aq_aa39 Aquifex aeolicus VF5 hypothetical protein NP_046427.1 35238 R 224324 CDS NP_046428.1 10957072 1192480 complement(37072..38037) 1 NC_001880.1 hypothetical protein 38037 1192480 aq_aa40 Aquifex aeolicus VF5 hypothetical protein NP_046428.1 37072 R 224324 CDS