-- dump date 20140618_204910 -- class Genbank::CDS -- table cds_note -- id note YP_001488955.1 Pfam matches to PF00308 Bac_DnaA, score 404.1, E-value 1.9E-118, and to PF08299 Bac_DnaA_C, score 60, E-value 7.2E-015 YP_001488956.1 binds the polymerase to DNA and acts as a sliding clamp YP_001488957.1 negatively supercoils closed circular double-stranded DNA YP_001488958.1 Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005 YP_001488959.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_001488962.1 Pfam match to PF08241 Methyltransf_11, score 34.3, E-value 1.3E-008 YP_001488963.1 Pfam match to PF00005 ABC_tran, score 202.3, E-value 1.1E-057 YP_001488964.1 Pfam match to PF00528 BPD_transp_1, score 69.5, E-value 1E-017 YP_001488966.1 Pfam match to PF01547 SBP_bac_1, score 31.8, E-value 2.1E-006 YP_001488967.1 Pfam match to PF03459 TOBE, score 61, E-value 3.4E-015; N-terminal:molybdenum-pterin binding domain YP_001488969.1 Pfam matches to PF00126 HTH_1, score 57.1, E-value 5.4E-014, and to PF03466 LysR_substrate, score 48.7, E-value 1.8E-011 YP_001488970.1 Pfam match to PF07690 MFS_1, score 99.6, E-value 1.1E-027 YP_001488972.1 Pfam match to PF00849 PseudoU_synth_2, score 141.6, E-value 2E-039 YP_001488973.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001488974.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001488975.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001488977.1 Pfam match to PF03061 4HBT, score 35, E-value 4.8E-009 YP_001488979.1 Pfam match to PF00691 OmpA, score 75.9, E-value 1.2E-019 YP_001488981.1 Pfam matches to PF00107 ADH_zinc_N, score 70.2, E-value 6E-018, and to PF08240 ADH_N, score 38.1, E-value 2.9E-008 YP_001488982.1 Pfam match to PF01638 DUF24, score 164.8, E-value 4E-052 YP_001488983.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001488984.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001488986.1 Pfam matches to PF02913 FAD-oxidase_C, score 231.9, E-value 1.2E-066, and to PF01565 FAD_binding_4, score 95.2, E-value 2.7E-026 YP_001488987.1 Pfam match to PF02652 Lactate_perm, score 950.5, E-value 6.1E-283 YP_001488988.1 Pfam matches to PF00072 Response_reg, score 81.2, E-value 2E-024, and to PF00486 Trans_reg_C, score 56.1, E-value 1.1E-013 YP_001488989.1 Pfam matches to PF02518 HATPase_c, score 74.1, E-value 3.9E-019, and to PF08448 PAS_4, score 54.9, E-value 1.4E-014 YP_001488990.1 Pfam match to PF02589 DUF162, score 34.4, E-value 3.2E-008 YP_001488992.1 Pfam match to PF02754 CCG, score 55.2, E-value 2E-013 YP_001488993.1 Pfam match to PF00383 dCMP_cyt_deam_1, score 125.7, E-value 1.2E-034 YP_001488994.1 Pfam match to PF00364 Biotin_lipoyl, score 94.5, E-value 2.8E-025 YP_001488995.1 biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001488996.1 Pfam matches to PF00270 DEAD, score 233.5, E-value 4.1E-067, and to PF00271 Helicase_C, score 128, E-value 1.8E-042 YP_001488997.1 Pfam match to PF01384 PHO4, score 434.4, E-value 1.4E-127 YP_001488998.1 Pfam match to PF03547 Auxin_eff, score 26.2, E-value 3.8E-008 YP_001488999.1 Pfam matches to PF00733 Asn_synthase, score 243.7, E-value 3.6E-070, and to PF00310 GATase_2, score -22.4, E-value 2.4E-009 YP_001489001.1 Pfam match to PF02562 PhoH, score 56.8, E-value 6.5E-014 YP_001489002.1 Pfam match to PF03653 UPF0093, score 173.1, E-value 6.2E-049 YP_001489003.1 Pfam match to PF00004 AAA, score 57, E-value 5E-017 YP_001489004.1 Pfam matches to PF01479 S4, score 54, E-value 4.5E-013, and to PF00849 PseudoU_synth_2, score 28, E-value 7.7E-009 YP_001489005.1 Pfam matches to PF01380 SIS, score 115.1, E-value 1.8E-031, and to PF00571 CBS, score 86.1, E-value 9.7E-023 YP_001489006.1 Pfam matches to PF00753 Lactamase_B, score 93.1, E-value 7.8E-025, and to PF07521 RMMBL, score 51.7, E-value 2.2E-012 YP_001489007.1 Pfam match to PF00398 RrnaAD, score 145.7, E-value 1.2E-040 YP_001489008.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001489011.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001489012.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001489013.1 Pfam match to PF00076 RRM_1, score 99, E-value 1.3E-026 YP_001489014.1 Pfam matches to PF00072 Response_reg, score 82.1, E-value 1.1E-024, and to PF00486 Trans_reg_C, score 69.6, E-value 9.2E-018 YP_001489015.1 Pfam matches to PF02518 HATPase_c, score 84.7, E-value 2.6E-022, and to PF00512 HisKA, score 35.1, E-value 2.2E-007 YP_001489017.1 Pfam match to PF02321 OEP, score 28.2, E-value 2.7E-005 YP_001489019.1 Pfam match to PF00873 ACR_tran, score 599.9, E-value 2.1E-177 YP_001489020.1 Pfam match to PF04264 YceI, score 234.1, E-value 2.7E-067 YP_001489021.1 Pfam match to PF05670 DUF814, score 73.9, E-value 4.8E-019 YP_001489025.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001489026.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001489027.1 Pfam match to PF01632 Ribosomal_L35p, score 42.6, E-value 1E-005 YP_001489028.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001489029.1 Pfam match to PF00581 Rhodanese, score 57.4, E-value 4.4E-014 YP_001489031.1 Pfam match to PF07992 Pyr_redox_2, score 49.4, E-value 1.1E-011 YP_001489033.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_001489034.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001489035.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001489036.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001489037.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001489040.1 Pfam matches to PF00563 EAL, score 127.7, E-value 2.9E-035, and to PF00990 GGDEF, score -12, E-value 3.7E-006 YP_001489041.1 Pfam match to PF00528 BPD_transp_1, score 60.3, E-value 5.9E-015 YP_001489042.1 Pfam match to PF00528 BPD_transp_1, score 48.7, E-value 1.8E-011 YP_001489043.1 Pfam match to PF00005 ABC_tran, score 187.1, E-value 3.8E-053 YP_001489046.1 Pfam matches to PF00072 Response_reg, score 103.8, E-value 2.4E-031, and to PF00486 Trans_reg_C, score 42.4, E-value 1.4E-009 YP_001489047.1 Pfam matches to PF02518 HATPase_c, score 64.8, E-value 2.5E-016, and to PF00512 HisKA, score 59.4, E-value 1.1E-014 YP_001489048.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001489049.1 forms a direct contact with the tRNA during translation YP_001489050.1 Pfam match to PF00496 SBP_bac_5, score 246.3, E-value 5.7E-071 YP_001489051.1 Pfam match to PF00702 Hydrolase, score 70.1, E-value 1.2E-019 YP_001489052.1 Pfam match to PF03401 Bug, score -36.5, E-value 1.3E-008 YP_001489054.1 Pfam match to PF01970 DUF112, score 629.2, E-value 3.2E-186 YP_001489055.1 Pfam matches to PF00072 Response_reg, score 96.8, E-value 3.3E-029, and to PF00486 Trans_reg_C, score 46.6, E-value 7.5E-011 YP_001489056.1 Pfam match to PF02518 HATPase_c, score 51.7, E-value 2.2E-012 YP_001489057.1 Pfam match to PF00484 Pro_CA, score 123.3, E-value 6.4E-034 YP_001489058.1 Pfam match to PF05145 AmoA, score 88.1, E-value 2.4E-023 YP_001489060.1 Pfam match to PF02470 MCE, score 70.7, E-value 4.3E-018 YP_001489061.1 Pfam match to PF00005 ABC_tran, score 170.2, E-value 4.8E-048 YP_001489062.1 Pfam match to PF02405 DUF140, score 282.3, E-value 8.5E-082 YP_001489065.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001489067.1 Pfam match to PF05430 DUF752, score 83.4, E-value 6.6E-022 YP_001489068.1 Pfam match to PF00768 Peptidase_S11, score 153.4, E-value 5.5E-043 YP_001489070.1 Pfam match to PF07681 DoxX, score 106.8, E-value 5.7E-029 YP_001489071.1 Pfam matches to PF02574 S-methyl_trans, score 258, E-value 1.8E-074, and to PF02965 Met_synt_B12, score 150, E-value 5.9E-042, and to PF00809 Pterin_bind, score 130.4, E-value 4.7E-036, and to PF02310 B12-binding, score 91.2, E-value 2.9E-024, and to PF02607 B12-binding_2, score 87.1, E-value 5E-023 YP_001489072.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001489073.1 Pfam match to PF01145 Band_7, score 108.4, E-value 1.8E-029 YP_001489075.1 Pfam matches to PF01502 PRA-CH, score 173.5, E-value 4.8E-049, and to PF01503 PRA-PH, score 98.2, E-value 2.2E-026 YP_001489078.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001489080.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations YP_001489081.1 Pfam match to PF00072 Response_reg, score 27.6, E-value 5.3E-008 YP_001489082.1 Pfam match to PF04608 PgpA, score 199.6, E-value 6.8E-057 YP_001489084.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001489085.1 Pfam match to PF04368 DUF507, score 225.9, E-value 8E-065 YP_001489086.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001489087.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001489088.1 Pfam match to PF00266 Aminotran_5, score -54, E-value 5.4E-010 YP_001489089.1 Pfam match to PF04264 YceI, score 156, E-value 8.9E-044 YP_001489090.1 Pfam match to PF01047 MarR, score 57.9, E-value 5.6E-016 YP_001489091.1 Pfam match to PF04264 YceI, score 219.5, E-value 6.9E-063 YP_001489092.1 Pfam match to PF02900 LigB, score 166.6, E-value 5.6E-047 YP_001489093.1 Pfam match to PF02678 Pirin, score 163.7, E-value 4.3E-046 YP_001489094.1 Pfam matches to PF00044 Gp_dh_N, score 85.9, E-value 1.1E-022, and to PF02800 Gp_dh_C, score 48.9, E-value 5.9E-012 YP_001489095.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001489096.1 Pfam match to PF01564 Spermine_synth, score 19.5, E-value 8.3E-006 YP_001489097.1 Pfam match to PF01121 CoaE, score 157.3, E-value 3.7E-044 YP_001489098.1 Pfam match to PF01678 DAP_epimerase, score 74.9, E-value 2.3E-019 YP_001489099.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001489100.1 Pfam match to PF00583 Acetyltransf_1, score 55.2, E-value 2E-013 YP_001489101.1 Pfam match to PF08238 Sel1, score 44.1, E-value 4.3E-010 YP_001489103.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001489105.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001489106.1 Pfam match to PF01197 Ribosomal_L31, score 135.8, E-value 1.1E-037 YP_001489107.1 Pfam match to PF00590 TP_methylase, score 75, E-value 2.1E-019 YP_001489108.1 Pfam matches to PF00588 SpoU_methylase, score 161.9, E-value 1.5E-045, and to PF08032 SpoU_sub_bind, score 62.1, E-value 1.7E-015 YP_001489110.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001489111.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001489112.1 Pfam match to PF05818 TraT, score 58.2, E-value 2.4E-014 YP_001489113.1 Pfam match to PF01148 CTP_transf_1, score 209.9, E-value 5.3E-060 YP_001489114.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001489116.1 Pfam match to PF06821 DUF1234, score 33.4, E-value 1.5E-010 YP_001489117.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001489118.1 Pfam match to PF01253 SUI1, score 33.1, E-value 2E-007 YP_001489119.1 Pfam matches to PF01256 Carb_kinase, score 189.8, E-value 5.9E-054, and to PF03853 YjeF_N, score 149.5, E-value 8.2E-042 YP_001489120.1 Pfam match to PF03091 CutA1, score 132.3, E-value 1E-037 YP_001489121.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001489122.1 Pfam matches to PF00364 Biotin_lipoyl, score 83.9, E-value 4.4E-022, and to PF00682 HMGL-like, score -49.1, E-value 6.8E-005 YP_001489124.1 Pfam matches to PF06445 AraC_E_bind, score 64.2, E-value 3.8E-016, and to PF00165 HTH_AraC, score 40.5, E-value 5.2E-009 YP_001489125.1 Pfam match to PF01699 Na_Ca_ex, score 167.1, E-value 4.2E-047 YP_001489126.1 Pfam match to PF00015 MCPsignal, score 164.2, E-value 3E-046 YP_001489127.1 Pfam matches to PF04851 ResIII, score 178.2, E-value 1.9E-050, and to PF00271 Helicase_C, score 46.1, E-value 5.6E-015 YP_001489128.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001489129.1 Pfam match to PF03788 LrgA, score 63.9, E-value 4.8E-016 YP_001489130.1 Pfam match to PF04172 LrgB, score 270.7, E-value 2.6E-078 YP_001489132.1 Pfam match to PF03994 DUF350, score 31.5, E-value 2.8E-006 YP_001489133.1 Pfam match to PF00375 SDF, score 317, E-value 3.1E-092 YP_001489136.1 Pfam match to PF01066 CDP-OH_P_transf, score 32.3, E-value 1.6E-006 YP_001489137.1 Pfam match to PF01148 CTP_transf_1, score 276.5, E-value 4.9E-080 YP_001489138.1 Pfam match to PF01553 Acyltransferase, score 65.2, E-value 7.2E-018 YP_001489139.1 Pfam matches to PF00501 AMP-binding, score 238.2, E-value 1.6E-068, and to PF01553 Acyltransferase, score 94.1, E-value 5.5E-026, and to PF07690 MFS_1, score 41, E-value 2.5E-011 YP_001489140.1 Pfam matches to PF08335 GlnD_UR_UTase, score 52.5, E-value 5.3E-013, and to PF01966 HD, score 35.5, E-value 1.6E-007 YP_001489141.1 Pfam match to PF02954 HTH_8, score 22.9, E-value 1.7E-005 YP_001489143.1 Pfam match to PF00023 Ank, score 28.6, E-value 5.2E-007 YP_001489144.1 Pfam match to PF00543 P-II, score 232.3, E-value 9.7E-076 YP_001489145.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001489146.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001489147.1 Pfam match to PF02119 FlgI, score 265.3, E-value 1.1E-076 YP_001489149.1 Pfam match to PF01313 Bac_export_3, score 83.3, E-value 7E-022 YP_001489152.1 Pfam match to PF03748 FliL, score 70, E-value 6.7E-018 YP_001489154.1 Pfam match to PF02107 FlgH, score 95.6, E-value 1.3E-025 YP_001489155.1 Pfam matches to PF06429 DUF1078, score 45.5, E-value 1.6E-010, and to PF00460 Flg_bb_rod, score 40.6, E-value 4.8E-009 YP_001489156.1 Pfam matches to PF07195 FliD_C, score 76.5, E-value 7.8E-020, and to PF02465 FliD_N, score 41.3, E-value 3.1E-009 YP_001489157.1 flagellin specific chaperone YP_001489159.1 Pfam match to PF01171 ATP_bind_3, score 223, E-value 6.1E-064 YP_001489160.1 Pfam matches to PF00919 UPF0004, score 144.6, E-value 2.4E-040, and to PF04055 Radical_SAM, score 76, E-value 1.1E-019 YP_001489161.1 Pfam match to PF02569 Pantoate_ligase, score 462.5, E-value 4.9E-136 YP_001489162.1 Pfam match to PF00528 BPD_transp_1, score 154.1, E-value 3.4E-043 YP_001489163.1 Pfam match to PF01648 ACPS, score 56.5, E-value 7.9E-014 YP_001489164.1 Pfam match to PF03616 Glt_symporter, score 680.5, E-value 1.1E-201 YP_001489165.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001489166.1 Pfam match to PF02219 MTHFR, score -39.4, E-value 4.1E-011 YP_001489167.1 Pfam match to PF00702 Hydrolase, score 77.7, E-value 8.1E-022 YP_001489168.1 Important for the balance of metabolites in the pentose-phosphate pathway YP_001489169.1 Pfam match to PF01474 DAHP_synth_2, score 863.2, E-value 1.2E-256 YP_001489170.1 Pfam match to PF03502 Channel_Tsx, score 145.8, E-value 1.1E-040 YP_001489172.1 Pfam match to PF03960 ArsC, score 110.6, E-value 4.3E-030 YP_001489173.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001489174.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001489175.1 Pfam match to PF02080 TrkA_C, score 41.5, E-value 2.7E-009 YP_001489176.1 Pfam match to PF00155 Aminotran_1_2, score 82.4, E-value 6.7E-023 YP_001489178.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001489179.1 Pfam match to PF02481 SMF, score 106.1, E-value 9.4E-029 YP_001489180.1 Pfam match to PF04748 Polysacc_deac_2, score 199.5, E-value 7.2E-057 YP_001489181.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001489182.1 Pfam match to PF00773 RNB, score 249.9, E-value 4.9E-072 YP_001489183.1 Pfam match to PF02623 DUF180, score 26.4, E-value 5.4E-007 YP_001489184.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001489185.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001489186.1 Pfam match to PF00436 SSB, score 90.8, E-value 3.8E-024 YP_001489187.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001489189.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001489190.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001489192.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001489193.1 Pfam match to PF04028 DUF374, score 99.1, E-value 1.2E-026 YP_001489195.1 Pfam match to PF04055 Radical_SAM, score 77.9, E-value 2.9E-020 YP_001489197.1 Pfam match to PF00484 Pro_CA, score 166.3, E-value 7.1E-047 YP_001489198.1 Pfam match to PF00155 Aminotran_1_2, score 78.2, E-value 1E-021 YP_001489199.1 Pfam match to PF02021 UPF0102, score 54.7, E-value 2.8E-013 YP_001489200.1 Pfam match to PF02597 ThiS, score 58, E-value 2.9E-014 YP_001489201.1 Pfam matches to PF00691 OmpA, score 77, E-value 5.3E-020, and to PF05433 Rick_17kDa_Anti, score 42.6, E-value 1.2E-009 YP_001489202.1 Pfam matches to PF00224 PK, score 492.1, E-value 1.2E-147, and to PF02887 PK_C, score 33.5, E-value 1.8E-008 YP_001489203.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001489204.1 Pfam match to PF06934 CTI, score 688.1, E-value 5.9E-204 YP_001489205.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001489206.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_001489207.1 Pfam match to PF00857 Isochorismatase, score 12.7, E-value 1.8E-008 YP_001489208.1 Pfam match to PF00486 Trans_reg_C, score 21.3, E-value 3.2E-005 YP_001489210.1 Pfam matches to PF03831 PhnA, score 93.1, E-value 7.7E-025, and to PF08274 PhnA_Zn_Ribbon, score 43, E-value 9.3E-010 YP_001489212.1 Pfam match to PF01925 DUF81, score 163.5, E-value 5E-046 YP_001489213.1 Pfam match to PF04982 HPP, score 110.5, E-value 4.4E-030 YP_001489214.1 Pfam match to PF03734 ErfK_YbiS_YhnG, score 49.8, E-value 8.6E-012 YP_001489218.1 Pfam matches to PF02826 2-Hacid_dh_C, score 212.9, E-value 6.8E-061, and to PF00389 2-Hacid_dh, score 69.8, E-value 1.2E-019 YP_001489220.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001489221.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001489222.1 Catalyzes the conversion of citrate to isocitrate YP_001489223.1 Pfam match to PF04303 DUF453, score 740, E-value 1.4E-219 YP_001489225.1 Pfam match to PF00857 Isochorismatase, score -18.7, E-value 6.8E-006 YP_001489227.1 Pfam matches to PF01379 Porphobil_deam, score 397.4, E-value 2E-116, and to PF03900 Porphobil_deamC, score 70.3, E-value 5.7E-018 YP_001489228.1 Pfam match to PF01323 DSBA, score 9.9, E-value 1.5E-005 YP_001489229.1 Pfam match to PF00004 AAA, score 32.4, E-value 1.3E-009 YP_001489230.1 Pfam match to PF01177 Asp_Glu_race, score 219.5, E-value 6.8E-063 YP_001489231.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001489232.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001489233.1 Pfam match to PF00578 AhpC-TSA, score 325.3, E-value 9.9E-095 YP_001489234.1 Pfam match to PF00037 Fer4, score 25.7, E-value 3E-005 YP_001489235.1 Pfam match to PF00334 NDK, score 279.7, E-value 5.3E-081 YP_001489237.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001489238.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001489239.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001489241.1 Pfam match to PF00350 Dynamin_N, score 113, E-value 7.6E-031 YP_001489242.1 Pfam match to PF00350 Dynamin_N, score 140, E-value 5.8E-039 YP_001489243.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001489244.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001489245.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_001489246.1 Pfam match to PF00361 Oxidored_q1, score 192.1, E-value 8.5E-056 YP_001489247.1 Pfam match to PF00361 Oxidored_q1, score 196.1, E-value 5.9E-057 YP_001489248.1 Pfam matches to PF00361 Oxidored_q1, score 322.2, E-value 8.4E-094, and to PF00662 Oxidored_q1_N, score 79, E-value 1.4E-020 YP_001489249.1 Pfam match to PF00420 Oxidored_q2, score 89.8, E-value 7.5E-024 YP_001489250.1 Pfam match to PF00499 Oxidored_q3, score 107.5, E-value 3.6E-029 YP_001489251.1 Pfam match to PF00037 Fer4, score 32.9, E-value 1E-006 YP_001489252.1 Pfam match to PF00146 NADHdh, score 338.9, E-value 8.1E-099 YP_001489253.1 Pfam match to PF00111 Fer2, score 35, E-value 5.5E-009 YP_001489254.1 Pfam match to PF00285 Citrate_synt, score 541.9, E-value 6.2E-160 YP_001489255.1 Pfam match to PF01512 Complex1_51K, score 349.9, E-value 3.9E-102 YP_001489256.1 Pfam match to PF01257 Complex1_24kDa, score 232, E-value 1.2E-066 YP_001489257.1 Pfam matches to PF00346 Complex1_49kDa, score 278.5, E-value 3.7E-096, and to PF00329 Complex1_30kDa, score 99.1, E-value 1.2E-026 YP_001489258.1 Pfam match to PF01058 Oxidored_q6, score 170.9, E-value 2.9E-048 YP_001489259.1 Pfam match to PF00507 Oxidored_q4, score 116.7, E-value 5.9E-032 YP_001489260.1 Pfam match to PF00155 Aminotran_1_2, score 101.4, E-value 3.3E-028 YP_001489261.1 Pfam match to PF01977 UbiD, score 503.1, E-value 2.9E-148 YP_001489263.1 Pfam match to PF06738 DUF1212, score 166, E-value 8.7E-047 YP_001489265.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001489266.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001489267.1 Pfam match to PF08242 Methyltransf_12, score 50.5, E-value 5.3E-012 YP_001489268.1 Pfam match to PF00015 MCPsignal, score 136, E-value 9.4E-038 YP_001489269.1 Pfam match to PF06977 SdiA-regulated, score 49, E-value 1.5E-011 YP_001489271.1 Pfam match to PF00579 tRNA-synt_1b, score 187.6, E-value 2.8E-053 YP_001489272.1 Pfam matches to PF00593 TonB_dep_Rec, score 101.5, E-value 2.3E-027, and to PF07715 Plug, score 67.1, E-value 5.2E-017 YP_001489274.1 Pfam match to PF07690 MFS_1, score 94.5, E-value 2.9E-026 YP_001489275.1 Pfam match to PF08242 Methyltransf_12, score 53.2, E-value 8E-013 YP_001489277.1 Pfam matches to PF00593 TonB_dep_Rec, score 86.1, E-value 1E-022, and to PF07715 Plug, score 68.4, E-value 2.1E-017 YP_001489279.1 Pfam match to PF02659 DUF204, score 70.3, E-value 5.8E-018 YP_001489280.1 Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045 YP_001489281.1 Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019 YP_001489282.1 Pfam matches to PF00005 ABC_tran, score 208, E-value 2E-059, and to PF00664 ABC_membrane, score 34, E-value 8.3E-009 YP_001489283.1 Pfam matches to PF00005 ABC_tran, score 210.6, E-value 3.3E-060, and to PF00664 ABC_membrane, score 36.2, E-value 2.2E-009 YP_001489284.1 Pfam matches to PF00593 TonB_dep_Rec, score 86.1, E-value 9.6E-023, and to PF07715 Plug, score 76.7, E-value 6.5E-020 YP_001489285.1 Pfam match to PF00165 HTH_AraC, score 26.4, E-value 9.1E-005 YP_001489286.1 Pfam matches to PF00593 TonB_dep_Rec, score 93.2, E-value 7E-025, and to PF07715 Plug, score 36.2, E-value 1E-007 YP_001489288.1 Pfam match to PF01545 Cation_efflux, score 295.2, E-value 1.1E-085 YP_001489289.1 Pfam matches to PF00587 tRNA-synt_2b, score 227.1, E-value 3.5E-065, and to PF02403 Seryl_tRNA_N, score 91, E-value 3.3E-024 YP_001489290.1 Pfam match to PF01578 Cytochrom_C_asm, score 146.5, E-value 6.5E-041 YP_001489291.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001489292.1 Pfam match to PF03264 Cytochrom_NNT, score 94.8, E-value 2.4E-025 YP_001489294.1 Pfam matches to PF00563 EAL, score 233.5, E-value 4.2E-067, and to PF00990 GGDEF, score 38.4, E-value 9.4E-011, and to PF08448 PAS_4, score 35.5, E-value 1.6E-007 YP_001489295.1 Pfam match to PF08447 PAS_3, score 53, E-value 5.4E-014 YP_001489296.1 Pfam match to PF03927 NapD, score 27, E-value 4.5E-006 YP_001489298.1 Pfam match to PF00037 Fer4, score 30.3, E-value 5.7E-006 YP_001489299.1 Pfam match to PF03892 NapB, score 87.9, E-value 2.9E-023 YP_001489300.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001489301.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001489302.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001489303.1 Pfam match to PF03480 SBP_bac_7, score 419.7, E-value 3.8E-123 YP_001489304.1 Pfam match to PF04290 DctQ, score 144.5, E-value 2.6E-040 YP_001489305.1 Pfam match to PF06808 DctM, score 532.1, E-value 5.4E-157 YP_001489306.1 Pfam match to PF02518 HATPase_c, score 69.3, E-value 1.1E-017 YP_001489307.1 Pfam matches to PF00072 Response_reg, score 82.6, E-value 7.2E-025, and to PF00486 Trans_reg_C, score 33.2, E-value 8.4E-007 YP_001489308.1 Pfam match to PF03737 Methyltransf_6, score 113.2, E-value 7.1E-031 YP_001489309.1 Pfam match to PF00590 TP_methylase, score 265.7, E-value 8.7E-077; non-fusion protein; does not contain precorrin-2 dehydrogenase or sirohydrochlorin ferrochelatase activity YP_001489311.1 Pfam match to PF00027 cNMP_binding, score 37.2, E-value 5.3E-008 YP_001489312.1 Pfam match to PF02885 Glycos_trans_3N, score 51.9, E-value 2E-012 YP_001489313.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001489314.1 Pfam match to PF00312 Ribosomal_S15, score 118.9, E-value 9.5E-034 YP_001489315.1 Pfam match to PF02082 Rrf2, score 113.1, E-value 4.4E-034 YP_001489317.1 Pfam match to PF02629 CoA_binding, score 45.6, E-value 1.6E-012 YP_001489318.1 Pfam matches to PF02518 HATPase_c, score 75.7, E-value 1.3E-019, and to PF00512 HisKA, score 46.2, E-value 1E-010, and to PF00672 HAMP, score 37.1, E-value 5.7E-008 YP_001489319.1 Pfam matches to PF00072 Response_reg, score 116.6, E-value 2.8E-035, and to PF00486 Trans_reg_C, score 78, E-value 2.7E-020 YP_001489320.1 Pfam match to PF00639 Rotamase, score 91, E-value 3.4E-024 YP_001489321.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001489322.1 Pfam match to PF00171 Aldedh, score 701.9, E-value 4.1E-208 YP_001489323.1 Pfam match to PF05610 DUF779, score 128.1, E-value 2.2E-035 YP_001489324.1 Pfam match to PF02472 ExbD, score 87.4, E-value 4.1E-023 YP_001489325.1 Pfam match to PF01618 MotA_ExbB, score 59.5, E-value 1E-014 YP_001489327.1 Pfam match to PF01202 SKI, score 115.2, E-value 1.7E-031 YP_001489328.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001489330.1 Pfam match to PF00348 polyprenyl_synt, score 136.9, E-value 5.1E-038 YP_001489331.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001489332.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001489333.1 Pfam match to PF00924 MS_channel, score 234.2, E-value 2.6E-067 YP_001489334.1 Pfam match to PF01743 PolyA_pol, score 120.4, E-value 4.8E-033 YP_001489337.1 Transfers the fatty acyl group on membrane lipoproteins YP_001489338.1 Pfam match to PF02699 YajC, score 131, E-value 3E-036 YP_001489339.1 Pfam match to PF02355 SecD_SecF, score -26.1, E-value 6.5E-007 YP_001489340.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001489343.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001489344.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001489346.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001489349.1 Pfam matches to PF04851 ResIII, score 99, E-value 1.3E-026, and to PF00271 Helicase_C, score 45.4, E-value 9.9E-015 YP_001489350.1 Pfam match to PF01553 Acyltransferase, score 32.2, E-value 1.3E-008 YP_001489354.1 Pfam matches to PF00270 DEAD, score 126.4, E-value 7.5E-035, and to PF02559 CarD_TRCF, score 120.6, E-value 4.1E-033, and to PF03461 TRCF, score 99.5, E-value 9E-027, and to PF00271 Helicase_C, score 71.7, E-value 1.5E-023 YP_001489355.1 Pfam match to PF00583 Acetyltransf_1, score 39.4, E-value 1.1E-008 YP_001489356.1 Pfam match to PF03372 Exo_endo_phos, score 36.3, E-value 4.6E-010 YP_001489358.1 Pfam matches to PF00072 Response_reg, score 118.1, E-value 9.6E-036, and to PF00486 Trans_reg_C, score 52.4, E-value 1.4E-012 YP_001489359.1 Pfam match to PF02518 HATPase_c, score 24.6, E-value 1.5E-006 YP_001489360.1 Pfam match to PF03486 HI0933_like, score 248.6, E-value 1.2E-071 YP_001489361.1 Pfam match to PF00015 MCPsignal, score 137, E-value 4.8E-038 YP_001489362.1 Pfam match to PF00072 Response_reg, score 108.6, E-value 8.3E-033 YP_001489363.1 Pfam match to PF08447 PAS_3, score 63.8, E-value 5.9E-017 YP_001489364.1 Pfam matches to PF02518 HATPase_c, score 69.6, E-value 8.8E-018, and to PF00989 PAS, score 43.6, E-value 1.1E-012, and to PF00512 HisKA, score 36.7, E-value 7.1E-008, and to PF00989 PAS, score 22.5, E-value 2.5E-006 YP_001489365.1 Pfam match to PF00149 Metallophos, score 41.3, E-value 3E-009 YP_001489368.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001489369.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001489370.1 Pfam match to PF01584 CheW, score 85.3, E-value 1.8E-022 YP_001489371.1 Pfam match to PF00160 Pro_isomerase, score 206.1, E-value 7.3E-059 YP_001489372.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001489373.1 Pfam match to PF02575 DUF149, score 99.8, E-value 7.7E-027 YP_001489374.1 Pfam match to PF00348 polyprenyl_synt, score 251, E-value 2.3E-072 YP_001489375.1 Pfam match to PF00166 Cpn10, score 135.9, E-value 1E-037 YP_001489376.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001489377.1 Pfam matches to PF02518 HATPase_c, score 122.1, E-value 1.4E-033, and to PF00512 HisKA, score 65.1, E-value 2.1E-016, and to PF00672 HAMP, score 36.1, E-value 1.1E-007 YP_001489378.1 Pfam matches to PF00072 Response_reg, score 131.1, E-value 1.1E-039, and to PF00486 Trans_reg_C, score 66.7, E-value 6.7E-017 YP_001489379.1 Pfam match to PF00149 Metallophos, score 59.2, E-value 1.2E-014 YP_001489384.1 Pfam match to PF00005 ABC_tran, score 213.2, E-value 5.5E-061 YP_001489385.1 Pfam match to PF02687 FtsX, score 120.8, E-value 3.4E-033 YP_001489386.1 Pfam match to PF03692 UPF0153, score 45.6, E-value 1.6E-010 YP_001489387.1 Pfam match to PF00459 Inositol_P, score 240, E-value 4.6E-069 YP_001489388.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001489389.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001489390.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001489391.1 Pfam match to PF02581 TMP-TENI, score 60.4, E-value 4.3E-020 YP_001489392.1 Pfam match to PF02590 DUF163, score 133.8, E-value 9.7E-055 YP_001489394.1 Pfam match to PF01207 Dus, score 290.2, E-value 3.7E-084 YP_001489395.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001489396.1 Pfam matches to PF00004 AAA, score 318.8, E-value 4.1E-096, and to PF01434 Peptidase_M41, score 326.4, E-value 4.6E-095, and to PF06480 FtsH_ext, score 129.7, E-value 7.2E-036 YP_001489397.1 Pfam matches to PF00072 Response_reg, score 108.1, E-value 1.1E-032, and to PF01966 HD, score 105.3, E-value 1.6E-028, and to PF08447 PAS_3, score 52.1, E-value 9.9E-014, and to PF00989 PAS, score 39.4, E-value 2.1E-011 YP_001489398.1 Pfam match to PF00072 Response_reg, score 108.5, E-value 8.6E-033 YP_001489399.1 Pfam matches to PF02518 HATPase_c, score 99.3, E-value 1E-026, and to PF00672 HAMP, score 58.6, E-value 1.8E-014 YP_001489400.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001489403.1 Pfam matches to PF00488 MutS_V, score 106.8, E-value 5.8E-029, and to PF05192 MutS_III, score 62.8, E-value 1.1E-015, and to PF01624 MutS_I, score 32.7, E-value 8.4E-009 YP_001489404.1 Pfam match to PF00873 ACR_tran, score 866.5, E-value 1.2E-257 YP_001489405.1 Pfam match to PF00529 HlyD, score 23, E-value 7.8E-006 YP_001489406.1 Pfam match to PF02321 OEP, score 47.4, E-value 4.3E-011 YP_001489407.1 Pfam match to PF00440 TetR_N, score 31.1, E-value 2.9E-008 YP_001489410.1 Pfam match to PF04055 Radical_SAM, score 70.4, E-value 5.3E-018 YP_001489413.1 Pfam matches to PF00005 ABC_tran, score 140.3, E-value 4.9E-039, and to PF00664 ABC_membrane, score 115.2, E-value 1.7E-031 YP_001489415.1 Pfam match to PF01266 DAO, score 31, E-value 1.3E-008 YP_001489416.1 Pfam match to PF00990 GGDEF, score 192, E-value 1.3E-054 YP_001489417.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001489418.1 Pfam matches to PF08338 DUF1731, score 71.9, E-value 1.8E-018, and to PF01370 Epimerase, score 18.5, E-value 1.8E-007 YP_001489419.1 Pfam match to PF00117 GATase, score 131.9, E-value 1.6E-036 YP_001489422.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001489423.1 Pfam match to PF02583 DUF156, score 70, E-value 7.2E-018 YP_001489424.1 Pfam matches to PF00122 E1-E2_ATPase, score 352.3, E-value 1.4E-106, and to PF00702 Hydrolase, score 125.1, E-value 2.5E-035, and to PF00403 HMA YP_001489425.1 Pfam match to PF00691 OmpA, score 131.5, E-value 2.1E-036 YP_001489426.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001489428.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001489429.1 Pfam match to PF03054 tRNA_Me_trans, score 568.7, E-value 3.6E-172 YP_001489430.1 Pfam match to PF01288 HPPK, score 123.9, E-value 4.1E-034 YP_001489431.1 Pfam match to PF00557 Peptidase_M24, score 149.1, E-value 1.1E-041 YP_001489432.1 Pfam match to PF01220 DHquinase_II, score 258.2, E-value 1.6E-074 YP_001489433.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline YP_001489434.1 Pfam match to PF01343 Peptidase_S49, score 204.8, E-value 1.8E-058 YP_001489436.1 Pfam match to PF00871 Acetate_kinase, score 692, E-value 4.9E-211 YP_001489437.1 Pfam match to PF01515 PTA_PTB, score 517.1, E-value 1.8E-152 YP_001489438.1 Pfam match to PF00871 Acetate_kinase, score 697.6, E-value 9.2E-213 YP_001489439.1 Pfam match to PF01545 Cation_efflux, score 8.6, E-value 2.6E-009 YP_001489440.1 Pfam match to PF00871 Acetate_kinase, score 680.8, E-value 1.2E-207 YP_001489441.1 Pfam match to PF00929 Exonuc_X-T, score 100.8, E-value 3.7E-027 YP_001489442.1 Pfam matches to PF03445 DUF294, score 204, E-value 3.2E-058, and to PF00571 CBS, score 57.2, E-value 4.7E-015, and to PF00027 cNMP_binding, score 49.8, E-value 8.5E-012 YP_001489443.1 Pfam match to PF00474 SSF, score 451.9, E-value 7.6E-133 YP_001489444.1 Pfam match to PF04341 DUF485, score 100.1, E-value 6E-027 YP_001489445.1 Pfam match to PF00474 SSF, score 467.5, E-value 1.5E-137 YP_001489446.1 Pfam match to PF04341 DUF485, score 114.6, E-value 2.5E-031 YP_001489447.1 Pfam match to PF00929 Exonuc_X-T, score 95, E-value 2E-025 YP_001489448.1 Pfam matches to PF03445 DUF294, score 180.7, E-value 3.3E-051, and to PF00571 CBS, score 57.3, E-value 4.4E-015, and to PF00027 cNMP_binding, score 37.1, E-value 5.6E-008 YP_001489449.1 Pfam match to PF00474 SSF, score 66.4, E-value 3E-019 YP_001489451.1 Pfam matches to PF00072 Response_reg, score 80.2, E-value 4.1E-024, and to PF00486 Trans_reg_C, score 51.7, E-value 2.2E-012 YP_001489452.1 Pfam matches to PF02518 HATPase_c, score 51.2, E-value 3.1E-012, and to PF00512 HisKA, score 28.3, E-value 2.5E-005 YP_001489453.1 Pfam match to PF02464 CinA, score 209.8, E-value 5.7E-060 YP_001489454.1 Pfam match to PF01266 DAO, score 44.9, E-value 1.5E-012 YP_001489455.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001489456.1 Pfam match to PF01106 NifU, score 72, E-value 1.7E-018 YP_001489458.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001489459.1 Pfam match to PF03595 C4dic_mal_tran, score 256.2, E-value 6.3E-074 YP_001489460.1 Pfam match to PF00248 Aldo_ket_red, score 184.6, E-value 2.2E-052 YP_001489461.1 Pfam match to PF01384 PHO4, score 196.2, E-value 7E-056 YP_001489462.1 Pfam matches to PF00015 MCPsignal, score 149.4, E-value 8.7E-042, and to PF00672 HAMP, score 52.8, E-value 1E-012 YP_001489464.1 Pfam match to PF00015 MCPsignal, score 161.4, E-value 2.2E-045 YP_001489465.1 Pfam match to PF03061 4HBT, score 58.8, E-value 1.1E-015 YP_001489466.1 membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation YP_001489467.1 Pfam match to PF01435 Peptidase_M48, score 164, E-value 1.4E-048 YP_001489468.1 Pfam match to PF02646 RmuC, score 408.3, E-value 1E-119 YP_001489469.1 Pfam match to PF00892 DUF6, score 62.3, E-value 1.5E-015 YP_001489470.1 Pfam matches to PF03453 MoeA_N, score 166.3, E-value 7.3E-047, and to PF00994 MoCF_biosynth, score 143.5, E-value 1.7E-041 YP_001489472.1 Pfam match to PF01171 ATP_bind_3, score 49, E-value 1.5E-011 YP_001489473.1 Pfam match to PF04463 DUF523, score 164.4, E-value 2.7E-046 YP_001489476.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001489477.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001489478.1 Pfam match to PF00005 ABC_tran, score 166.6, E-value 5.9E-047 YP_001489480.1 Essential for recycling GMP and indirectly, cGMP YP_001489481.1 Pfam matches to PF00563 EAL, score 162.7, E-value 8.4E-046, and to PF00072 Response_reg, score 97.6, E-value 1.9E-029, and to PF00990 GGDEF, score -14, E-value 5.2E-006 YP_001489482.1 Pfam matches to PF00122 E1-E2_ATPase, score 235.2, E-value 4.2E-071, and to PF00702 Hydrolase, score 89.6, E-value 3.3E-025 YP_001489483.1 Pfam match to PF03597 CcoS, score 38.6, E-value 1.9E-008 YP_001489485.1 Pfam match to PF00005 ABC_tran, score 156.8, E-value 5E-044 YP_001489486.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001489487.1 Pfam matches to PF02421 FeoB_N, score 137.3, E-value 3.8E-038, and to PF01926 MMR_HSR1, score 121, E-value 3.1E-033, and to PF07664 FeoB_C, score 70.2, E-value 6.1E-018, and to PF07670 Gate, score 69.8, E-value 7.8E-018 YP_001489488.1 Pfam match to PF04023 FeoA, score 61, E-value 3.6E-015 YP_001489489.1 Pfam match to PF02698 DUF218, score 119, E-value 1.2E-032 YP_001489490.1 Pfam match to PF00005 ABC_tran, score 181.4, E-value 2E-051 YP_001489491.1 Pfam match to PF00950 ABC-3, score 272, E-value 1.1E-078 YP_001489493.1 Pfam match to PF08534 Redoxin, score 141.3, E-value 2.4E-039 YP_001489494.1 Pfam match to PF08238 Sel1, score 43, E-value 9.1E-010 YP_001489495.1 Pfam match to PF01758 SBF, score 23, E-value 2.5E-006 YP_001489497.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001489498.1 Pfam match to PF01794 Ferric_reduct, score 50.3, E-value 2E-013 YP_001489499.1 Pfam match to PF00580 UvrD-helicase, score 311.6, E-value 1.3E-090 YP_001489500.1 Pfam match to PF00999 Na_H_Exchanger, score 148.1, E-value 2.1E-041 YP_001489501.1 Pfam matches to PF00174 Oxidored_molyb, score 200.4, E-value 3.7E-057, and to PF03404 Mo-co_dimer, score 56.6, E-value 7.7E-014 YP_001489503.1 Pfam match to PF00034 Cytochrom_C, score 33.7, E-value 5.9E-007 YP_001489508.1 Pfam match to PF02872 5_nucleotid_C, score 75.8, E-value 1.2E-019 YP_001489512.1 Pfam match to PF00561 Abhydrolase_1, score 30.7, E-value 2.2E-008 YP_001489513.1 Pfam match to PF01965 DJ-1_PfpI, score 94.3, E-value 9E-021 YP_001489514.1 Pfam match to PF00753 Lactamase_B, score 97.5, E-value 3.6E-026 YP_001489517.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001489521.1 Pfam match to PF07690 MFS_1, score 215.8, E-value 8.7E-062 YP_001489522.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001489526.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001489528.1 Pfam matches to PF05362 Lon_C, score 325.6, E-value 8.2E-095, and to PF00004 AAA, score 159.6, E-value 4.9E-048, and to PF02190 LON, score 18.5, E-value 1.2E-007 YP_001489529.1 Pfam match to PF01694 Rhomboid, score 102.1, E-value 1.5E-027 YP_001489530.1 Pfam match to PF01451 LMWPc, score 128, E-value 2.4E-035 YP_001489532.1 Pfam match to PF00515 TPR_1, score 27.8, E-value 3.6E-005 YP_001489533.1 Pfam match to PF01047 MarR, score 80.9, E-value 1.3E-022 YP_001489535.1 Pfam match to PF01381 HTH_3, score 26.9, E-value 1.4E-006 YP_001489536.1 Pfam matches to PF00015 MCPsignal, score 116, E-value 9.9E-032, and to PF08447 PAS_3, score 71, E-value 6E-019 YP_001489538.1 Pfam match to PF00892 DUF6, score 47.8, E-value 7.7E-012 YP_001489539.1 Pfam matches to PF02786 CPSase_L_D2, score 350.1, E-value 3.4E-102, and to PF02785 Biotin_carb_C, score 211.5, E-value 1.7E-060, and to PF00289 CPSase_L_chain, score 135.4, E-value 1.4E-037 YP_001489540.1 Pfam match to PF01883 DUF59, score 79.8, E-value 7.9E-021 YP_001489541.1 Pfam match to PF02657 SufE, score 90.5, E-value 4.7E-024 YP_001489542.1 Pfam match to PF00266 Aminotran_5, score 476, E-value 4.3E-140 YP_001489543.1 Pfam match to PF01458 UPF0051, score 56.8, E-value 6.6E-014 YP_001489544.1 Pfam match to PF00005 ABC_tran, score 105.8, E-value 1.2E-028 YP_001489545.1 Pfam match to PF01458 UPF0051, score 449.6, E-value 3.7E-132 YP_001489546.1 Pfam match to PF00266 Aminotran_5, score 321, E-value 1.9E-093 YP_001489547.1 Pfam matches to PF01592 NifU_N, score 203.6, E-value 4.1E-058, and to PF01106 NifU, score 92.6, E-value 1.1E-024, and to PF04324 Fer2_BFD, score 46.3, E-value 9.5E-011 YP_001489548.1 Pfam match to PF00571 CBS, score 94.2, E-value 3.6E-025 YP_001489549.1 Pfam match to PF00990 GGDEF, score 142, E-value 1.3E-040 YP_001489550.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001489551.1 Pfam matches to PF00072 Response_reg, score 45.7, E-value 1.5E-013, and to PF01584 CheW, score 36.7, E-value 7.4E-008 YP_001489552.1 Pfam match to PF00899 ThiF, score 101.6, E-value 2.2E-027 YP_001489553.1 Pfam matches to PF01272 GreA_GreB, score 117.5, E-value 3.5E-032, and to PF03449 GreA_GreB_N, score 99.7, E-value 7.8E-027 YP_001489554.1 Pfam match to PF00149 Metallophos, score 30.7, E-value 4.8E-006 YP_001489555.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001489556.1 Pfam match to PF00015 MCPsignal, score 153.2, E-value 6E-043 YP_001489557.1 Pfam match to PF00730 HhH-GPD, score 74, E-value 4.2E-019 YP_001489559.1 Pfam matches to PF00593 TonB_dep_Rec, score 68.2, E-value 2.4E-017, and to PF07715 Plug, score 40.8, E-value 4.4E-009 YP_001489560.1 Pfam matches to PF00593 TonB_dep_Rec, score 86.3, E-value 8.5E-023, and to PF07715 Plug, score 67.8, E-value 3.2E-017 YP_001489561.1 Pfam match to PF00015 MCPsignal, score 116.1, E-value 9E-032 YP_001489564.1 Pfam matches to PF00072 Response_reg, score 92.3, E-value 7.7E-028, and to PF00486 Trans_reg_C, score 74.2, E-value 3.6E-019 YP_001489565.1 Pfam matches to PF02518 HATPase_c, score 50.2, E-value 6.5E-012, and to PF08447 PAS_3, score 23.2, E-value 9.5E-006, and to PF00989 PAS, score 20.4, E-value 1.1E-005 YP_001489566.1 Pfam match to PF00015 MCPsignal, score 152.6, E-value 9.6E-043 YP_001489567.1 Pfam match to PF00015 MCPsignal, score 163.7, E-value 4.4E-046 YP_001489569.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001489570.1 Pfam match to PF00717 Peptidase_S24, score 74.6, E-value 2.9E-019 YP_001489571.1 Pfam matches to PF02882 THF_DHG_CYH_C, score 345, E-value 1.1E-100, and to PF00763 THF_DHG_CYH, score 201.6, E-value 1.7E-057 YP_001489572.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001489573.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001489574.1 Pfam match to PF03739 YjgP_YjgQ, score 111.7, E-value 1.9E-030 YP_001489575.1 Pfam match to PF00293 NUDIX, score 30.6, E-value 4.9E-006 YP_001489576.1 Pfam match to PF01520 Amidase_3, score 258.9, E-value 9.3E-075 YP_001489577.1 Pfam match to PF03060 NPD, score 358.2, E-value 1.7E-105 YP_001489578.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001489579.1 Pfam matches to PF04607 RelA_SpoT, score 163.9, E-value 3.7E-046, and to PF02824 TGS, score 51.4, E-value 2.8E-012, and to PF01966 HD, score 36.2, E-value 1E-007 YP_001489580.1 Pfam match to PF01192 RNA_pol_Rpb6, score 37.2, E-value 5.1E-008 YP_001489581.1 Catalyzes the phosphorylation of UMP to UDP YP_001489583.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001489584.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001489585.1 Pfam matches to PF00425 Chorismate_bind, score 421.5, E-value 1.1E-123, and to PF04715 Anth_synt_I_N, score 50.4, E-value 1.2E-014 YP_001489586.1 Pfam match to PF05036 SPOR, score 32.8, E-value 3.7E-009 YP_001489587.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001489588.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001489589.1 Pfam match to PF02674 Colicin_V, score 95.9, E-value 1.1E-025 YP_001489590.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001489591.1 Pfam match to PF00990 GGDEF, score 135.9, E-value 7.2E-039 YP_001489592.1 unwinds double stranded DNA YP_001489593.1 Pfam matches to PF03721 UDPG_MGDP_dh_N, score 182.6, E-value 8.9E-052, and to PF00984 UDPG_MGDP_dh, score 132.5, E-value 1.1E-036, and to PF03720 UDPG_MGDP_dh_C, score 27, E-value 2.1E-006 YP_001489594.1 Pfam match to PF01370 Epimerase, score 214.5, E-value 2.2E-061 YP_001489595.1 Pfam matches to PF03721 UDPG_MGDP_dh_N, score 239.8, E-value 5.3E-069, and to PF00984 UDPG_MGDP_dh, score 149.4, E-value 8.5E-042, and to PF03720 UDPG_MGDP_dh_C, score 98.5, E-value 1.9E-026 YP_001489596.1 Pfam match to PF01408 GFO_IDH_MocA, score 51.9, E-value 5.4E-014 YP_001489598.1 Pfam match to PF01041 DegT_DnrJ_EryC1, score 493.3, E-value 2.7E-145 YP_001489599.1 Pfam match to PF01266 DAO, score 146.4, E-value 3.9E-041 YP_001489600.1 Pfam match to PF01370 Epimerase, score 220.8, E-value 2.7E-063 YP_001489601.1 Pfam match to PF01041 DegT_DnrJ_EryC1, score 330.4, E-value 2.9E-096 YP_001489602.1 Pfam matches to PF00733 Asn_synthase, score 260.9, E-value 2.4E-075, and to PF00310 GATase_2, score 55.8, E-value 7.4E-018 YP_001489605.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001489606.1 Pfam match to PF00977 His_biosynth, score 262.6, E-value 7.2E-076 YP_001489608.1 Pfam match to PF00534 Glycos_transf_1, score 27.1, E-value 4.4E-007 YP_001489609.1 Pfam matches to PF00005 ABC_tran, score 208.3, E-value 1.6E-059, and to PF00664 ABC_membrane, score 23.1, E-value 7E-006 YP_001489610.1 Pfam match to PF01757 Acyl_transf_3, score 230.1, E-value 4.5E-066 YP_001489611.1 Pfam match to PF00534 Glycos_transf_1, score 153.7, E-value 4.3E-043 YP_001489612.1 Pfam matches to PF00733 Asn_synthase, score 295.3, E-value 1.1E-085, and to PF00310 GATase_2, score 17.8, E-value 2.2E-012 YP_001489613.1 Pfam match to PF00534 Glycos_transf_1, score 122.3, E-value 1.2E-033 YP_001489614.1 Pfam match to PF00953 Glycos_transf_4, score 121.2, E-value 2.7E-033 YP_001489616.1 Pfam match to PF01943 Polysacc_synt, score 27.1, E-value 9.9E-006 YP_001489621.1 Pfam match to PF00534 Glycos_transf_1, score 151.5, E-value 2E-042 YP_001489622.1 Pfam match to PF01171 ATP_bind_3, score 18, E-value 3.8E-005 YP_001489623.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001489624.1 Pfam match to PF00977 His_biosynth, score 306.8, E-value 3.6E-089 YP_001489625.1 Pfam match to PF00534 Glycos_transf_1, score 41.1, E-value 5.7E-011 YP_001489626.1 Pfam match to PF02350 Epimerase_2, score 481.9, E-value 6.9E-142 YP_001489627.1 Pfam match to PF00535 Glycos_transf_2, score 106, E-value 2.5E-031 YP_001489628.1 Pfam match to PF00953 Glycos_transf_4, score 66.6, E-value 7.5E-017 YP_001489629.1 Pfam match to PF00908 dTDP_sugar_isom, score 191.8, E-value 1.5E-054 YP_001489630.1 Pfam match to PF02719 Polysacc_synt_2, score 584.2, E-value 1.1E-172 YP_001489632.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001489633.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001489634.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001489636.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001489637.1 Pfam match to PF03544 TonB, score 42.7, E-value 1.1E-009 YP_001489638.1 Pfam match to PF02472 ExbD, score 135.5, E-value 1.3E-037 YP_001489639.1 Pfam match to PF01618 MotA_ExbB, score 142.4, E-value 1.1E-039 YP_001489640.1 Pfam match to PF02321 OEP, score 33.9, E-value 5.2E-007 YP_001489641.1 Pfam match to PF00529 HlyD, score 38.7, E-value 5E-010 YP_001489642.1 Pfam match to PF00005 ABC_tran, score 204.7, E-value 2E-058 YP_001489643.1 Pfam match to PF02687 FtsX, score 169.8, E-value 6.2E-048 YP_001489644.1 Pfam match to PF00023 Ank, score 26.1, E-value 2.7E-006 YP_001489645.1 Pfam matches to PF00122 E1-E2_ATPase, score 100.8, E-value 2.2E-030, and to PF00702 Hydrolase, score 105.1, E-value 1.2E-029 YP_001489651.1 Pfam match to PF01475 FUR, score 118.7, E-value 1.5E-032 YP_001489653.1 Pfam match to PF00206 Lyase_1, score 518.7, E-value 6.1E-153 YP_001489655.1 Pfam matches to PF07568 HisKA_2, score 95, E-value 2.1E-025, and to PF00672 HAMP, score 38.9, E-value 1.6E-008, and to PF02518 HATPase_c, score 31.1, E-value 3.6E-006 YP_001489656.1 Pfam matches to PF00072 Response_reg, score 54, E-value 4.4E-016, and to PF00486 Trans_reg_C, score 35.1, E-value 2.2E-007 YP_001489657.1 Pfam matches to PF00593 TonB_dep_Rec, score 87.2, E-value 4.7E-023, and to PF07715 Plug, score 54.4, E-value 3.5E-013 YP_001489658.1 Pfam match to PF03171 2OG-FeII_Oxy, score 41.9, E-value 2E-009 YP_001489659.1 Pfam match to PF01070 FMN_dh, score 408.1, E-value 1.1E-119 YP_001489660.1 Pfam matches to PF07715 Plug, score 117.4, E-value 3.8E-032, and to PF00593 TonB_dep_Rec, score 95.4, E-value 1.6E-025 YP_001489661.1 Pfam match to PF00756 Esterase, score -3.2, E-value 1.3E-005 YP_001489662.1 Pfam match to PF08242 Methyltransf_12, score 39.1, E-value 1.4E-008 YP_001489664.1 Pfam match to PF03929 DUF337, score 135, E-value 1E-032 YP_001489665.1 Pfam match to PF04328 DUF466, score 110.9, E-value 3.3E-030 YP_001489666.1 Pfam match to PF02554 CstA, score 845.6, E-value 2.4E-251 YP_001489667.1 Pfam matches to PF06071 DUF933, score 211.3, E-value 2E-060, and to PF01926 MMR_HSR1, score 121.9, E-value 1.6E-033 YP_001489671.1 Pfam match to PF06865 DUF1255, score 122.4, E-value 1.2E-033 YP_001489672.1 Pfam match to PF05573 NosL, score 35.5, E-value 3.5E-010 YP_001489673.1 Pfam matches to PF00990 GGDEF, score 201.8, E-value 1.5E-057, and to PF08447 PAS_3, score 64.1, E-value 4.7E-017 YP_001489674.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001489675.1 catalyzes the modification of U13 in tRNA(Glu) YP_001489677.1 Pfam matches to PF00015 MCPsignal, score 122.4, E-value 1.1E-033, and to PF00672 HAMP, score 44.4, E-value 3.6E-010 YP_001489678.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001489679.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001489680.1 Pfam match to PF00561 Abhydrolase_1, score 27.7, E-value 1.5E-007 YP_001489681.1 Pfam match to PF08245 Mur_ligase_M, score 35.6, E-value 6.3E-010 YP_001489682.1 Pfam match to PF01230 HIT, score 21.6, E-value 3.4E-006 YP_001489685.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001489686.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001489687.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001489688.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001489689.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001489690.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001489691.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001489692.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001489693.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001489694.1 one of the stabilizing components for the large ribosomal subunit YP_001489695.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001489696.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001489697.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001489698.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001489699.1 Pfam match to PF00253 Ribosomal_S14, score 80.5, E-value 4.7E-021 YP_001489700.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001489701.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001489702.1 Pfam match to PF00861 Ribosomal_L18p, score 132.5, E-value 1.1E-036 YP_001489703.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001489704.1 late assembly protein YP_001489705.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001489706.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001489707.1 Pfam match to PF01176 eIF-1a, score 116.4, E-value 7.7E-032 YP_001489708.1 Pfam match to PF03167 UDG, score 39.4, E-value 1.1E-008 YP_001489710.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001489711.1 Pfam match to PF01584 CheW, score 34.8, E-value 2.8E-007 YP_001489712.1 Pfam match to PF08497 Radical_SAM_N, score 562.1, E-value 5.2E-166 YP_001489713.1 Pfam matches to PF00406 ADK, score 297.6, E-value 2.1E-086, and to PF05191 ADK_lid, score 76, E-value 1.1E-019 YP_001489714.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001489715.1 Pfam match to PF00994 MoCF_biosynth, score 52.3, E-value 6E-015 YP_001489716.1 Pfam match to PF00302 CAT, score 378.6, E-value 8.5E-111 YP_001489717.1 Pfam matches to PF08240 ADH_N, score 113.4, E-value 5.8E-031, and to PF00107 ADH_zinc_N, score 69.6, E-value 9.1E-018 YP_001489718.1 Pfam match to PF00465 Fe-ADH, score 45.4, E-value 7.6E-016 YP_001489719.1 Pfam match to PF00015 MCPsignal, score 167.9, E-value 2.4E-047 YP_001489720.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001489721.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001489722.1 Pfam matches to PF00015 MCPsignal, score 163.8, E-value 4.1E-046, and to PF02743 Cache_1, score 58, E-value 2.8E-014 YP_001489723.1 Pfam match to PF00015 MCPsignal, score 172.2, E-value 1.2E-048 YP_001489724.1 Pfam match to PF00015 MCPsignal, score 163.8, E-value 4.1E-046 YP_001489725.1 Pfam match to PF00015 MCPsignal, score 156.2, E-value 7.9E-044 YP_001489726.1 Pfam matches to PF00072 Response_reg, score 89.4, E-value 6.1E-027, and to PF00486 Trans_reg_C, score 48.1, E-value 2.7E-011 YP_001489727.1 Pfam matches to PF00072 Response_reg, score 103.8, E-value 2.4E-031, and to PF02518 HATPase_c, score 69.7, E-value 8.7E-018, and to PF00512 HisKA, score 36.2, E-value 1E-007 YP_001489728.1 Pfam matches to PF02518 HATPase_c, score 132.7, E-value 9.5E-037, and to PF00072 Response_reg, score 120.7, E-value 1.6E-036, and to PF00512 HisKA, score 88.8, E-value 1.5E-023 YP_001489729.1 Pfam match to PF00293 NUDIX, score 67.6, E-value 3.6E-017 YP_001489733.1 Pfam match to PF01094 ANF_receptor, score 48.2, E-value 2E-006 YP_001489734.1 Pfam match to PF02653 BPD_transp_2, score 99.1, E-value 3E-021 YP_001489735.1 Pfam match to PF02653 BPD_transp_2, score 73, E-value 6E-014 YP_001489736.1 Pfam match to PF00005 ABC_tran, score 154.2, E-value 3.1E-043 YP_001489737.1 Pfam match to PF00005 ABC_tran, score 140.3, E-value 4.9E-039 YP_001489739.1 Pfam match to PF01774 UreD, score 64.7, E-value 1.4E-019 YP_001489740.1 Pfam matches to PF00547 Urease_gamma, score 222.2, E-value 1E-063, and to PF00699 Urease_beta, score 220.9, E-value 2.5E-063 YP_001489741.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001489743.1 Pfam match to PF01730 UreF, score -23.9, E-value 9.1E-005 YP_001489744.1 Pfam match to PF02492 cobW, score 193.7, E-value 6.7E-056 YP_001489746.1 Pfam match to PF00440 TetR_N, score 31.5, E-value 2.2E-008 YP_001489748.1 Pfam match to PF00529 HlyD, score 70.6, E-value 1.5E-018 YP_001489749.1 Pfam match to PF02321 OEP, score 76.7, E-value 6.5E-020 YP_001489750.1 Pfam match to PF01047 MarR, score 36.1, E-value 1E-009 YP_001489754.1 Pfam match to PF00990 GGDEF, score 183.2, E-value 5.9E-052 YP_001489755.1 Pfam match to PF03372 Exo_endo_phos, score 173.8, E-value 3.9E-049 YP_001489757.1 Pfam match to PF01925 DUF81, score 19.5, E-value 1.2E-006 YP_001489759.1 Pfam match to PF08212 Lipocalin_2, score 220.3, E-value 3.9E-063 YP_001489760.1 Pfam match to PF04055 Radical_SAM, score 35.9, E-value 1.3E-007 YP_001489762.1 Pfam match to PF03109 ABC1, score 84.6, E-value 2.8E-022 YP_001489764.1 Pfam match to PF00563 EAL, score 170.5, E-value 3.8E-048 YP_001489765.1 Pfam matches to PF00072 Response_reg, score 107.9, E-value 1.3E-032, and to PF04397 LytTR, score 84.9, E-value 2.3E-022 YP_001489766.1 Pfam match to PF06580 His_kinase, score 100, E-value 6.4E-027 YP_001489768.1 Pfam matches to PF03441 FAD_binding_7, score 272.4, E-value 8.4E-079, and to PF00875 DNA_photolyase, score 37.7, E-value 1.5E-008 YP_001489769.1 Pfam matches to PF08349 DUF1722, score 144.6, E-value 2.5E-040, and to PF04463 DUF523, score 72.3, E-value 1.4E-018 YP_001489770.1 Pfam match to PF03547 Auxin_eff, score 52.2, E-value 4.4E-016 YP_001489771.1 Pfam match to PF04074 DUF386, score 64.7, E-value 2.8E-016 YP_001489772.1 catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate YP_001489773.1 Pfam match to PF00483 NTP_transferase, score 48.4, E-value 2.7E-013 YP_001489774.1 Pfam matches to PF02878 PGM_PMM_I, score 130.5, E-value 4.3E-036, and to PF02879 PGM_PMM_II, score 121, E-value 3.1E-033, and to PF00408 PGM_PMM_IV, score 66, E-value 4.5E-018, and to PF02880 PGM_PMM_III, score 60.4, E-value 5.3E-015 YP_001489775.1 Pfam match to PF00015 MCPsignal, score 171.9, E-value 1.5E-048 YP_001489776.1 Pfam match to PF08447 PAS_3, score 46.7, E-value 3.1E-012 YP_001489777.1 Pfam match to PF01361 Tautomerase, score 61.5, E-value 1.4E-018 YP_001489778.1 Pfam matches to PF00126 HTH_1, score 65.2, E-value 1.9E-016, and to PF03466 LysR_substrate, score 38.7, E-value 1.9E-008 YP_001489779.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001489781.1 Pfam match to PF03692 UPF0153, score 53.4, E-value 6.8E-013 YP_001489783.1 Pfam match to PF00037 Fer4, score 29.5, E-value 7.6E-006 YP_001489784.1 Pfam match to PF01855 POR_N, score 303, E-value 4.9E-088 YP_001489785.1 Pfam match to PF02775 TPP_enzyme_C, score 176.5, E-value 6.3E-055 YP_001489786.1 Pfam match to PF01558 POR, score 95.2, E-value 1.8E-025 YP_001489787.1 3'-5' exonuclease of DNA polymerase III YP_001489788.1 Pfam match to PF00697 PRAI, score 130.6, E-value 3.9E-036 YP_001489789.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001489790.1 Pfam match to PF02253 PLA1, score 173.8, E-value 4E-049 YP_001489792.1 Pfam match to PF00293 NUDIX, score 55.6, E-value 1.5E-013 YP_001489793.1 Pfam match to PF04461 DUF520, score 198.8, E-value 1.2E-056 YP_001489795.1 Pfam match to PF04241 DUF423, score 122.3, E-value 1.2E-033 YP_001489796.1 Pfam match to PF00156 Pribosyltran, score 36.6, E-value 8E-008 YP_001489799.1 Pfam match to PF01168 Ala_racemase_N, score 19.7, E-value 4.3E-008 YP_001489800.1 Pfam match to PF02163 Peptidase_M50, score 251.6, E-value 1.5E-072 YP_001489801.1 Pfam match to PF01066 CDP-OH_P_transf, score 106.9, E-value 5.6E-029 YP_001489802.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_001489803.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001489804.1 Pfam matches to PF05193 Peptidase_M16_C, score 151.8, E-value 1.7E-042, and to PF00675 Peptidase_M16, score 79.1, E-value 1.1E-021 YP_001489805.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001489806.1 Pfam matches to PF00005 ABC_tran, score 182.4, E-value 1E-051, and to PF00664 ABC_membrane, score 135.5, E-value 1.4E-037 YP_001489807.1 Pfam match to PF03023 MVIN, score 317, E-value 3.1E-092 YP_001489808.1 Pfam match to PF03372 Exo_endo_phos, score 62.1, E-value 2.4E-017 YP_001489809.1 Pfam match to PF01475 FUR, score 86, E-value 1E-022 YP_001489810.1 Pfam match to PF02130 UPF0054, score 137.4, E-value 3.6E-038 YP_001489812.1 Pfam match to PF03575 Peptidase_S51, score 217.4, E-value 2.8E-062 YP_001489813.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001489814.1 Pfam match to PF05728 UPF0227, score 139.8, E-value 6.6E-039 YP_001489815.1 Pfam match to PF03150 CCP_MauG, score 224.8, E-value 1.7E-064 YP_001489816.1 Pfam matches to PF00563 EAL, score 345.5, E-value 8E-101, and to PF00990 GGDEF, score 187, E-value 4.3E-053, and to PF00989 PAS, score 39.9, E-value 1.4E-011 YP_001489818.1 Pfam match to PF00448 SRP54, score 373.5, E-value 3E-109 YP_001489819.1 Pfam match to PF08534 Redoxin, score 72.9, E-value 9.1E-019 YP_001489820.1 Pfam match to PF01812 5-FTHF_cyc-lig, score 73.7, E-value 5.3E-019 YP_001489821.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_001489822.1 Pfam match to PF03602 Cons_hypoth95, score 131.7, E-value 1.9E-036 YP_001489823.1 Pfam match to PF00528 BPD_transp_1, score 113.6, E-value 5.3E-031 YP_001489827.1 Pfam match to PF07927 YcfA, score 58.5, E-value 2E-014 YP_001489828.1 Pfam match to PF00106 adh_short, score 17.5, E-value 2.5E-007 YP_001489833.1 Pfam matches to PF00072 Response_reg, score 104.3, E-value 1.6E-031, and to PF00486 Trans_reg_C, score 43.7, E-value 5.7E-010 YP_001489834.1 Pfam match to PF02518 HATPase_c, score 92.2, E-value 1.5E-024 YP_001489835.1 Pfam matches to PF01729 QRPTase_C, score 112, E-value 1.6E-030, and to PF02749 QRPTase_N, score 38.1, E-value 2.7E-008 YP_001489836.1 Pfam match to PF00990 GGDEF, score 164.2, E-value 5E-047 YP_001489837.1 Pfam match to PF02637 GatB_Yqey, score 99.2, E-value 1.1E-026 YP_001489838.1 Pfam match to PF00005 ABC_tran, score 169.8, E-value 6.1E-048 YP_001489840.1 Pfam match to PF03486 HI0933_like, score 23.5, E-value 1.5E-006 YP_001489841.1 Pfam match to PF00561 Abhydrolase_1, score 27.6, E-value 1.6E-007 YP_001489845.1 Pfam match to PF02696 UPF0061, score 58.7, E-value 1.1E-015 YP_001489846.1 Pfam match to PF07883 Cupin_2, score 78.7, E-value 1.7E-020 YP_001489850.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001489851.1 Pfam match to PF00890 FAD_binding_2, score 229, E-value 9.4E-066 YP_001489853.1 Pfam match to PF01863 DUF45, score 148.9, E-value 1.2E-041 YP_001489854.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001489855.1 Pfam match to PF01545 Cation_efflux, score 271, E-value 2.2E-078 YP_001489856.1 Pfam matches to PF01966 HD, score 39.4, E-value 1.2E-009, and to PF01590 GAF, score 35.5, E-value 1.7E-007, and to PF00753 Lactamase_B, score 22.8, E-value 1.9E-006 YP_001489857.1 Pfam matches to PF00211 Guanylate_cyc, score 119.1, E-value 1.2E-032, and to PF05226 CHASE2, score 109.4, E-value 9.4E-030 YP_001489860.1 Pfam match to PF01757 Acyl_transf_3, score 3.3, E-value 2.3E-005 YP_001489862.1 Pfam match to PF07690 MFS_1, score 127.6, E-value 3.2E-035 YP_001489864.1 Pfam match to PF01891 CbiM, score 63.2, E-value 8E-016 YP_001489866.1 Pfam match to PF02361 CbiQ, score 9.9, E-value 8E-005 YP_001489867.1 Pfam match to PF00005 ABC_tran, score 189.9, E-value 5.7E-054 YP_001489868.1 Pfam matches to PF08479 POTRA_2, score 98.6, E-value 1.7E-026, and to PF03865 ShlB, score -85.3, E-value 4.8E-011 YP_001489869.1 Pfam match to PF05860 Haemagg_act, score 134.4, E-value 2.9E-037 YP_001489882.1 Pfam match to PF01594 UPF0118, score 117.8, E-value 2.9E-032 YP_001489887.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001489889.1 Pfam match to PF08447 PAS_3, score 41.7, E-value 7.5E-011 YP_001489890.1 Pfam match to PF01019 G_glu_transpept, score 637.4, E-value 1.1E-188 YP_001489891.1 Pfam match to PF01925 DUF81, score -3.2, E-value 1.8E-005 YP_001489893.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001489894.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001489895.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001489896.1 Pfam match to PF01467 CTP_transf_2, score 105.1, E-value 9.2E-030 YP_001489897.1 Pfam match to PF02441 Flavoprotein, score 127.7, E-value 3E-035 YP_001489899.1 Pfam matches to PF01281 Ribosomal_L9_N, score 73.5, E-value 6.1E-019, and to PF03948 Ribosomal_L9_C, score 65.5, E-value 2.7E-018 YP_001489900.1 heat shock protein involved in degradation of misfolded proteins YP_001489901.1 heat shock protein involved in degradation of misfolded proteins YP_001489903.1 Pfam match to PF01026 TatD_DNase, score 239.5, E-value 6.7E-069. Possible pseudogene/truncated protein. G:A transition (Met:Ile) at bp 979145 results in a potential start codon shift to bp 979287. N-terminal sequence downstream of ly mutated start codon at 979143 corresponds to N-terminal sequences of similar proteins in T. denitrificans and W. succinogenes. Good RBS present at bp 979132-979137. YP_001489904.1 Pfam matches to PF01464 SLT, score 74.5, E-value 3.1E-019, and to PF01476 LysM, score 52, E-value 1.9E-012 YP_001489905.1 Pfam matches to PF03330 DPBB_1, score 151.8, E-value 1.7E-042, and to PF05036 SPOR, score 36.6, E-value 2.7E-010 YP_001489906.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001489907.1 Pfam match to PF08282 Hydrolase_3, score 29.9, E-value 3.1E-009 YP_001489909.1 Pfam match to PF03968 OstA, score 62.4, E-value 1.4E-015 YP_001489910.1 Pfam match to PF01926 MMR_HSR1, score 88.3, E-value 2.1E-023 YP_001489911.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_001489912.1 Pfam matches to PF08281 Sigma70_r4_2, score 61.6, E-value 3.4E-017, and to PF04542 Sigma70_r2, score 32, E-value 1.9E-006 YP_001489913.1 Pfam match to PF04773 FecR, score 80.4, E-value 5.2E-021 YP_001489914.1 Pfam matches to PF00593 TonB_dep_Rec, score 79.6, E-value 8.7E-021, and to PF07715 Plug, score 41.8, E-value 2.2E-009 YP_001489915.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001489916.1 Pfam match to PF00392 GntR, score 54.6, E-value 1E-015 YP_001489918.1 Pfam match to PF01243 Pyridox_oxidase, score 28.3, E-value 2.5E-005 YP_001489919.1 Pfam match to PF00873 ACR_tran, score 35, E-value 1E-009 YP_001489920.1 Pfam match to PF00873 ACR_tran, score 62.2, E-value 4.6E-017 YP_001489921.1 Pfam match to PF00529 HlyD, score 38.2, E-value 6.7E-010 YP_001489922.1 Pfam match to PF02321 OEP, score 60.5, E-value 5E-015 YP_001489923.1 Pfam matches to PF01966 HD, score 111.9, E-value 1.7E-030, and to PF08447 PAS_3, score 68.1, E-value 3.9E-018 YP_001489924.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001489925.1 Pfam matches to PF00905 Transpeptidase, score 230.4, E-value 3.5E-066, and to PF03717 PBP_dimer, score 108.6, E-value 1.7E-029 YP_001489927.1 Pfam match to PF01551 Peptidase_M23, score 63.9, E-value 2.3E-020 YP_001489929.1 Pfam match to PF00005 ABC_tran, score 166.3, E-value 7.1E-047 YP_001489930.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001489931.1 Pfam match to PF00041 fn3, score 31.5, E-value 2.1E-008 YP_001489932.1 Pfam matches to PF00849 PseudoU_synth_2, score 177.2, E-value 3.8E-050, and to PF01479 S4, score 39.1, E-value 1.4E-008 YP_001489933.1 Pfam match to PF01098 FTSW_RODA_SPOVE, score 300.1, E-value 3.8E-087 YP_001489935.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001489936.1 Pfam match to PF06865 DUF1255, score 168.4, E-value 1.7E-047 YP_001489940.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001489941.1 Pfam match to PF00694 Aconitase_C, score 68.1, E-value 2.5E-017 YP_001489942.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001489943.1 Pfam match to PF02272 DHHA1, score 19.7, E-value 7.2E-005 YP_001489944.1 Pfam match to PF01230 HIT, score 25.1, E-value 8E-008 YP_001489945.1 Pfam match to PF00444 Ribosomal_L36, score 34.9, E-value 2E-003 YP_001489946.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001489947.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001489948.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001489949.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001489950.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001489951.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001489952.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001489953.1 Pfam match to PF07883 Cupin_2, score 33.9, E-value 5E-007 YP_001489955.1 Pfam match to PF00497 SBP_bac_3, score 74.6, E-value 2.8E-019 YP_001489956.1 Pfam matches to PF00072 Response_reg, score 76.1, E-value 7.3E-023, and to PF00486 Trans_reg_C, score 57.5, E-value 4.1E-014 YP_001489957.1 Pfam match to PF02321 OEP, score 27.4, E-value 4.6E-005 YP_001489959.1 Pfam matches to PF05345 He_PIG, score 40.6, E-value 7.8E-011, and to PF00028 Cadherin, score 38.5, E-value 1.9E-010 YP_001489961.1 Pfam match to PF02163 Peptidase_M50, score 10.4, E-value 8.8E-005 YP_001489962.1 Pfam match to PF00226 DnaJ, score 39.7, E-value 3.4E-011 YP_001489963.1 Pfam match to PF00226 DnaJ, score 27.6, E-value 1.3E-007 YP_001489964.1 Pfam match to PF00933 Glyco_hydro_3, score 108.8, E-value 3.9E-031 YP_001489965.1 Pfam matches to PF02518 HATPase_c, score 58.7, E-value 1.8E-014, and to PF07695 7TMR-DISM_7TM, score 35, E-value 2.4E-007 YP_001489966.1 Pfam matches to PF00072 Response_reg, score 61.6, E-value 2.1E-018, and to PF00486 Trans_reg_C, score 33.6, E-value 6.4E-007 YP_001489968.1 Pfam match to PF00005 ABC_tran, score 79.8, E-value 7.6E-021 YP_001489969.1 Pfam match to PF08281 Sigma70_r4_2, score 50.3, E-value 6.8E-014 YP_001489970.1 Pfam match to PF04773 FecR, score 56.7, E-value 7.1E-014 YP_001489971.1 Pfam matches to PF00107 ADH_zinc_N, score 117.2, E-value 4.1E-032, and to PF08240 ADH_N, score 74.1, E-value 4E-019 YP_001489973.1 Pfam match to PF00027 cNMP_binding, score 27.1, E-value 5.7E-005 YP_001489974.1 Pfam match to PF00892 DUF6, score 73.2, E-value 7.5E-019 YP_001489975.1 Pfam match to PF01638 DUF24, score 126.6, E-value 5.9E-040 YP_001489976.1 Pfam match to PF02525 Flavodoxin_2, score 148.1, E-value 3.9E-044 YP_001489977.1 Pfam match to PF00939 Na_sulph_symp, score -198.5, E-value 4.2E-006 YP_001489978.1 Pfam match to PF00893 Multi_Drug_Res, score 157.1, E-value 4.2E-044 YP_001489979.1 Pfam match to PF00892 DUF6, score 61.1, E-value 3.2E-015 YP_001489980.1 Pfam match to PF00165 HTH_AraC, score 43.7, E-value 5.6E-010 YP_001489981.1 Pfam match to PF01161 PBP, score 33.2, E-value 8.1E-008 YP_001489982.1 Pfam matches to PF03466 LysR_substrate, score 82.5, E-value 1.2E-021, and to PF00126 HTH_1, score 49.9, E-value 2.1E-012 YP_001489983.1 Pfam match to PF03601 Cons_hypoth698, score 364.4, E-value 1.6E-106 YP_001489985.1 Pfam match to PF03547 Auxin_eff, score 112.8, E-value 1.3E-034 YP_001489986.1 Pfam match to PF01638 DUF24, score 119.1, E-value 1.4E-037 YP_001489987.1 Pfam match to PF02525 Flavodoxin_2, score 127.4, E-value 6.2E-038 YP_001489988.1 Pfam match to PF03992 ABM, score 48.2, E-value 2.5E-011 YP_001489989.1 Pfam match to PF00724 Oxidored_FMN, score 270.5, E-value 3E-078 YP_001489990.1 Pfam match to PF00892 DUF6, score 79.5, E-value 9.8E-021 YP_001489991.1 Pfam match to PF00881 Nitroreductase, score 173.4, E-value 5.3E-049 YP_001489993.1 Pfam match to PF00005 ABC_tran, score 156.9, E-value 4.8E-044 YP_001489994.1 Pfam match to PF03061 4HBT, score 68.7, E-value 1.8E-018 YP_001489995.1 Pfam match to PF00015 MCPsignal, score 160.7, E-value 3.4E-045 YP_001489996.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001489997.1 Pfam match to PF03738 GSP_synth, score 594.4, E-value 9.8E-176 YP_001489999.1 Pfam match to PF01966 HD, score 25.8, E-value 4.9E-005 YP_001490000.1 Pfam match to PF02661 Fic, score 72.3, E-value 7E-014; similar to MloA YP_001490002.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001490003.1 Pfam match to PF08241 Methyltransf_11, score 82.1, E-value 1.6E-021 YP_001490004.1 Pfam match to PF02578 DUF152, score 167.4, E-value 3.3E-047 YP_001490005.1 Pfam matches to PF03949 Malic_M, score 344.3, E-value 1.8E-100, and to PF00390 malic, score 255.6, E-value 9.5E-074 YP_001490006.1 Pfam match to PF00551 Formyl_trans_N, score 187.6, E-value 2.8E-053 YP_001490007.1 Pfam match to PF00588 SpoU_methylase, score 148.3, E-value 1.8E-041 YP_001490009.1 Pfam match to PF02690 Na_Pi_cotrans, score 89.9, E-value 6.9E-024 YP_001490012.1 Pfam matches to PF00072 Response_reg, score 101.6, E-value 1.1E-030, and to PF00486 Trans_reg_C, score 52.1, E-value 1.7E-012 YP_001490013.1 Pfam match to PF02518 HATPase_c, score 45.6, E-value 1.5E-010 YP_001490014.1 Pfam match to PF01145 Band_7, score 241.4, E-value 1.8E-069 YP_001490015.1 Pfam match to PF01957 NfeD, score 25.3, E-value 2.9E-006 YP_001490016.1 Pfam match to PF02579 Nitro_FeMo-Co, score 28.6, E-value 2E-005 YP_001490017.1 Pfam match to PF02322 Cyto_ox_2, score 27.3, E-value 1.1E-013 YP_001490018.1 Pfam match to PF01654 Bac_Ubq_Cox, score 600.9, E-value 1.1E-177 YP_001490022.1 Pfam match to PF08238 Sel1, score 53, E-value 9.3E-013 YP_001490024.1 Pfam match to PF03588 Leu_Phe_trans, score 253.4, E-value 4.3E-073 YP_001490025.1 Pfam match to PF00849 PseudoU_synth_2, score 63.7, E-value 5.4E-016 YP_001490026.1 Pfam match to PF00702 Hydrolase, score 98.3, E-value 1E-027 YP_001490030.1 Pfam matches to PF07715 Plug, score 71.3, E-value 2.8E-018, and to PF00593 TonB_dep_Rec, score 55.6, E-value 1.5E-013 YP_001490031.1 Pfam match to PF01497 Peripla_BP_2, score 63.1, E-value 3.4E-017 YP_001490032.1 Pfam match to PF00005 ABC_tran, score 84.7, E-value 3.4E-023 YP_001490033.1 Pfam match to PF01032 FecCD, score 173.7, E-value 4.2E-049 YP_001490034.1 Pfam match to PF00300 PGAM, score 76.4, E-value 8E-020 YP_001490035.1 Pfam match to PF00005 ABC_tran, score 166.4, E-value 6.6E-047 YP_001490037.1 Pfam matches to PF00072 Response_reg, score 82.5, E-value 8.1E-025, and to PF00486 Trans_reg_C, score 79.5, E-value 9.6E-021 YP_001490038.1 Pfam matches to PF02518 HATPase_c, score 84.1, E-value 3.9E-022, and to PF00512 HisKA, score 41.7, E-value 2.4E-009 YP_001490040.1 Pfam match to PF05433 Rick_17kDa_Anti, score 31.8, E-value 2.1E-006 YP_001490042.1 Pfam match to PF00929 Exonuc_X-T, score 20.6, E-value 1.7E-005 YP_001490043.1 Pfam match to PF00990 GGDEF, score 149.7, E-value 7.3E-043 YP_001490044.1 Pfam match to PF01381 HTH_3, score 64.1, E-value 8.2E-017 YP_001490045.1 Pfam matches to PF00270 DEAD, score 144.4, E-value 2.7E-040, and to PF00271 Helicase_C, score 105.8, E-value 5.3E-035. Possible pseudogene/truncated protein. G:A transition (Met:Ile) at bp 1115517 results in a potential start codon shift to bp 1115285. Possible RBS present at bp 1115527-1115532. YP_001490046.1 Pfam match to PF02518 HATPase_c, score 82.4, E-value 1.3E-021 YP_001490047.1 Pfam matches to PF00072 Response_reg, score 107.8, E-value 1.4E-032, and to PF00486 Trans_reg_C, score 44.4, E-value 3.5E-010 YP_001490048.1 Pfam matches to PF00691 OmpA, score 87.6, E-value 3.5E-023, and to PF02321 OEP, score 78.1, E-value 2.6E-020 YP_001490049.1 Pfam matches to PF00005 ABC_tran, score 185, E-value 1.6E-052, and to PF00664 ABC_membrane, score 33.5, E-value 1.1E-008 YP_001490050.1 Pfam match to PF00529 HlyD, score 46.2, E-value 9.8E-011 YP_001490051.1 Pfam match to PF00196 GerE, score 59.3, E-value 5E-016 YP_001490053.1 Pfam matches to PF00563 EAL, score -66.7, E-value 3.1E-006, and to PF00990 GGDEF, score -26.6, E-value 4.6E-005, and to PF00672 HAMP, score 26.5, E-value 8.8E-005 YP_001490054.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001490055.1 Pfam match to PF00924 MS_channel, score 102.1, E-value 1.6E-027 YP_001490056.1 Pfam matches to PF00919 UPF0004, score 109.3, E-value 9.9E-030, and to PF04055 Radical_SAM, score 79.4, E-value 1E-020 YP_001490057.1 Pfam match to PF00004 AAA, score 265.9, E-value 4E-080 YP_001490059.1 Pfam match to PF00994 MoCF_biosynth, score 126.2, E-value 1.9E-036 YP_001490060.1 Pfam match to PF00926 DHBP_synthase, score 338.4, E-value 1.1E-098 YP_001490062.1 Pfam match to PF00300 PGAM, score 36.5, E-value 8.7E-008 YP_001490066.1 Pfam match to PF01381 HTH_3, score 31.9, E-value 6.1E-008 YP_001490069.1 Pfam match to PF00005 ABC_tran, score 82.3, E-value 1E-016 YP_001490070.1 Pfam match to PF06445 AraC_E_bind, score 57.7, E-value 3.5E-014 YP_001490072.1 Pfam matches to PF00384 Molybdopterin, score 440.3, E-value 2.3E-129, and to PF01568 Molydop_binding, score 119.2, E-value 1.1E-032 YP_001490073.1 Pfam match to PF00561 Abhydrolase_1, score 53.4, E-value 8.5E-015 YP_001490074.1 Pfam match to PF00440 TetR_N, score 31.1, E-value 3E-008 YP_001490075.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_001490076.1 Pfam matches to PF01595 DUF21, score 278.3, E-value 1.3E-080, and to PF00571 CBS, score 107.3, E-value 4.2E-029, and to PF03471 CorC_HlyC, score 66.9, E-value 3.6E-018 YP_001490078.1 Pfam match to PF05359 DUF748, score 53.5, E-value 6.5E-013 YP_001490079.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001490080.1 Pfam match to PF00909 Ammonium_transp, score 471.1, E-value 1.3E-138 YP_001490081.1 Pfam match to PF00543 P-II, score 211.9, E-value 4.3E-069 YP_001490082.1 Pfam match to PF01066 CDP-OH_P_transf, score 44.3, E-value 3.8E-010 YP_001490083.1 Pfam match to PF02541 Ppx-GppA, score 29.8, E-value 1.7E-008 YP_001490085.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine resistant; also known as acetolactate synthase 3 large subunit YP_001490086.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001490087.1 Pfam match to PF04613 LpxD, score 85.1, E-value 2E-022 YP_001490088.1 Pfam match to PF01580 FtsK_SpoIIIE, score 282.8, E-value 6.1E-082. Possible pseudogene/truncated protein. G:A transition (Met:Ile) at bp 1163905 results in a potential start codon shift to bp 1264050. Possible RBS present at bp 1163891-1163895. YP_001490089.1 Pfam matches to PF00072 Response_reg, score 112, E-value 7.1E-034, and to PF00486 Trans_reg_C, score 56.1, E-value 1E-013 YP_001490090.1 Pfam matches to PF02518 HATPase_c, score 22.7, E-value 5.5E-006, and to PF00672 HAMP, score 29.1, E-value 1.4E-005 YP_001490092.1 Pfam matches to PF07568 HisKA_2, score 109.8, E-value 7E-030, and to PF07695 7TMR-DISM_7TM, score 78.4, E-value 2.1E-020, and to PF02518 HATPase_c, score 44.8, E-value 2.7E-010 YP_001490093.1 Pfam matches to PF00072 Response_reg, score 74.3, E-value 2.7E-022, and to PF00486 Trans_reg_C, score 63.7, E-value 5.6E-016 YP_001490095.1 Pfam matches to PF00072 Response_reg, score 70.9, E-value 2.9E-021, and to PF00486 Trans_reg_C, score 32.4, E-value 1.4E-006 YP_001490099.1 Pfam match to PF02810 SEC-C, score 29.3, E-value 1.2E-005 YP_001490103.1 Pfam match to PF02482 Ribosomal_S30AE, score 43.8, E-value 5.4E-010 YP_001490104.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001490105.1 Pfam matches to PF00916 Sulfate_transp, score 277, E-value 3.3E-080, and to PF01740 STAS, score 41, E-value 1.9E-011 YP_001490106.1 Pfam match to PF02602 HEM4, score 50.6, E-value 4.8E-012 YP_001490108.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001490109.1 Pfam match to PF06271 RDD, score 83.1, E-value 7.7E-022 YP_001490112.1 Pfam matches to PF01138 RNase_PH, score 138.9, E-value 1.2E-038, and to PF03725 RNase_PH_C, score 75.3, E-value 1.8E-019, and to PF00575 S1, score 55.5, E-value 1.6E-013, and to PF00013 KH_1, score 48.3, E-value 2.4E-011, and to PF03725 RNase_PH_C, score 30.9, E-value 4E-006, and to PF03726 PNPase, score 30.3, E-value 6.4E-006 YP_001490113.1 Pfam match to PF00072 Response_reg, score 126.3, E-value 3.1E-038 YP_001490114.1 Pfam matches to PF02518 HATPase_c, score 98.9, E-value 1.4E-026, and to PF01584 CheW, score 76.8, E-value 6.2E-020, and to PF02895 H-kinase_dim, score 54.3, E-value 3.6E-013, and to PF01627 Hpt, score 41.3, E-value 3E-009 YP_001490115.1 Pfam match to PF01739 CheR, score 176.7, E-value 5.2E-050 YP_001490116.1 Pfam match to PF03975 CheD, score 64.9, E-value 2.4E-016 YP_001490117.1 Pfam matches to PF01339 CheB_methylest, score 277.4, E-value 2.6E-080, and to PF00072 Response_reg, score 96.5, E-value 4E-029 YP_001490119.1 Pfam match to PF07690 MFS_1, score 159.2, E-value 9.5E-045 YP_001490120.1 Pfam match to PF00589 Phage_integrase, score 112.2, E-value 2.5E-031 YP_001490121.1 Pfam match to PF01903 CbiX, score 93.5, E-value 2.7E-026 YP_001490124.1 Pfam match to PF01432 Peptidase_M3, score 467.9, E-value 1.1E-137 YP_001490125.1 Pfam match to PF08241 Methyltransf_11, score 32.8, E-value 3.3E-008 YP_001490126.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001490127.1 hydrolyzes diadenosine polyphosphate YP_001490128.1 Pfam matches to PF00696 AA_kinase, score 224.8, E-value 1.7E-064, and to PF01842 ACT, score 40.7, E-value 1.1E-010 YP_001490131.1 Pfam match to PF00809 Pterin_bind, score 285.7, E-value 8.1E-083 YP_001490133.1 Pfam match to PF02353 CMAS, score 359.4, E-value 5.4E-105 YP_001490134.1 Pfam match to PF07103 DUF1365, score 52.3, E-value 4.7E-015 YP_001490135.1 Pfam match to PF01593 Amino_oxidase, score 32.5, E-value 3.5E-009 YP_001490136.1 Pfam match to PF08212 Lipocalin_2, score 91.4, E-value 1E-025 YP_001490137.1 Pfam match to PF07690 MFS_1, score 30.9, E-value 1.6E-008 YP_001490138.1 Pfam match to PF00106 adh_short, score -4, E-value 6.8E-006 YP_001490139.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_001490140.1 Pfam matches to PF01103 Bac_surface_Ag, score 132.3, E-value 1.2E-036, and to PF07244 Surf_Ag_VNR, score 60.8, E-value 4E-015 YP_001490141.1 Pfam match to PF04055 Radical_SAM, score 77.3, E-value 4.3E-020 YP_001490142.1 Pfam match to PF05193 Peptidase_M16_C, score 101.5, E-value 3.1E-028 YP_001490143.1 charges one glutamine molecule and pairs it with tRNA(Gln) YP_001490144.1 Pfam match to PF02325 YGGT, score 66.9, E-value 5.8E-017 YP_001490145.1 Pfam match to PF01464 SLT, score 51.5, E-value 2.6E-012 YP_001490147.1 Pfam match to PF03205 MobB, score 85.6, E-value 1.4E-022 YP_001490148.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001490150.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001490152.1 Pfam match to PF00717 Peptidase_S24, score 54.3, E-value 3.8E-013 YP_001490155.1 Pfam matches to PF00364 Biotin_lipoyl, score 83.9, E-value 4.4E-022, and to PF00682 HMGL-like, score -49.1, E-value 6.8E-005 YP_001490156.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001490157.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_001490158.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001490162.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001490163.1 Pfam match to PF00925 GTP_cyclohydro2, score 284.8, E-value 1.5E-082 YP_001490164.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001490165.1 Pfam matches to PF02518 HATPase_c, score 82.2, E-value 1.4E-021, and to PF08447 PAS_3, score 57.3, E-value 3.5E-015 YP_001490166.1 Pfam matches to PF00072 Response_reg, score 118.4, E-value 8.3E-036, and to PF00486 Trans_reg_C, score 31.3, E-value 3.2E-006 YP_001490167.1 Pfam match to PF04055 Radical_SAM, score 69.9, E-value 7.4E-018 YP_001490169.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001490170.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001490171.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001490174.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001490175.1 Pfam match to PF01041 DegT_DnrJ_EryC1, score 245.6, E-value 9.3E-071 YP_001490176.1 Pfam match to PF02540 NAD_synthase, score 364, E-value 2.2E-106 YP_001490178.1 Pfam match to PF04324 Fer2_BFD, score 34.9, E-value 2.6E-007 YP_001490179.1 Pfam match to PF00226 DnaJ, score 51.8, E-value 9E-015 YP_001490181.1 Pfam match to PF02416 MttA_Hcf106, score 23.2, E-value 1.5E-005 YP_001490182.1 Pfam match to PF00902 TatC, score 287, E-value 3.2E-083 YP_001490183.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001490184.1 Pfam match to PF00929 Exonuc_X-T, score 51.6, E-value 2.4E-012 YP_001490186.1 Pfam match to PF03772 Competence, score 112.5, E-value 1.1E-030 YP_001490188.1 Pfam match to PF08241 Methyltransf_11, score 32.8, E-value 1.1E-006 YP_001490192.1 Pfam match to PF02754 CCG, score 53.3, E-value 7.2E-013 YP_001490193.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001490195.1 Pfam match to PF00072 Response_reg, score 25.3, E-value 2.7E-007 YP_001490196.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001490198.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001490199.1 Pfam matches to PF00563 EAL, score 237.7, E-value 2.3E-068, and to PF00990 GGDEF, score 45.7, E-value 7.3E-013 YP_001490200.1 Pfam match to PF00005 ABC_tran, score 231.2, E-value 2.1E-066 YP_001490201.1 Pfam match to PF02367 UPF0079, score 82.7, E-value 1E-021 YP_001490202.1 Pfam match to PF00591 Glycos_transf_3, score 362.7, E-value 5.5E-106 YP_001490204.1 Pfam match to PF01479 S4, score 36.1, E-value 1.1E-007 YP_001490205.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001490206.1 Pfam match to PF00501 AMP-binding, score 298.6, E-value 1.1E-086 YP_001490207.1 Pfam match to PF03062 MBOAT, score 119.9, E-value 6.4E-033 YP_001490212.1 Pfam matches to PF00916 Sulfate_transp, score 325.2, E-value 1.1E-094, and to PF01740 STAS, score 38, E-value 1.5E-010 YP_001490213.1 Pfam match to PF00582 Usp, score 67.4, E-value 4.2E-017 YP_001490214.1 Pfam match to PF02254 TrkA_N, score 117.3, E-value 4.1E-032 YP_001490215.1 Pfam match to PF02386 TrkH, score 287.3, E-value 2.7E-083 YP_001490216.1 Pfam matches to PF00072 Response_reg, score 88, E-value 1.7E-026, and to PF00486 Trans_reg_C, score 68.5, E-value 1.9E-017 YP_001490217.1 Pfam matches to PF02518 HATPase_c, score 99, E-value 1.3E-026, and to PF00512 HisKA, score 52.2, E-value 1.6E-012 YP_001490219.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001490220.1 Pfam matches to PF01556 DnaJ_C, score 216.3, E-value 6.4E-062, and to PF00226 DnaJ, score 135.2, E-value 1.5E-039, and to PF00684 DnaJ_CXXCXGXG, score 89.8, E-value 7.8E-024 YP_001490221.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001490224.1 Pfam match to PF04305 DUF455, score 215.6, E-value 1.1E-061 YP_001490225.1 Pfam match to PF00753 Lactamase_B, score 96.5, E-value 7.1E-026 YP_001490226.1 Pfam match to PF00990 GGDEF, score 100.8, E-value 9.7E-029 YP_001490227.1 Pfam match to PF00990 GGDEF, score 79.7, E-value 1.2E-022 YP_001490228.1 Pfam match to PF08003 Methyltransf_9, score 320.1, E-value 3.6E-093 YP_001490230.1 Pfam match to PF01578 Cytochrom_C_asm, score 147, E-value 4.6E-041 YP_001490231.1 Pfam match to PF01546, Peptidase_M20, score 57.1, E-value 4E-009 YP_001490233.1 Pfam matches to PF00015 MCPsignal, score 148.4, E-value 1.8E-041, and to PF08269 Cache_2, score 58, E-value 2.9E-014 YP_001490235.1 Pfam match to PF03548 LolA, score 93.8, E-value 4.8E-025 YP_001490236.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001490237.1 Pfam match to PF02687 FtsX, score 148.1, E-value 2.2E-041 YP_001490239.1 Pfam match to PF02618 ADC_lyase, score 202.8, E-value 7.3E-058 YP_001490240.1 Pfam match to PF03971 IDH, score 1106, E-value 0.0 YP_001490241.1 Pfam matches to PF00056 Ldh_1_N, score 128.6, E-value 1.6E-035, and to PF02866 Ldh_1_C, score 126, E-value 9.9E-035 YP_001490244.1 Pfam match to PF00877 NLPC_P60, score 20.7, E-value 3.4E-006 YP_001490246.1 Pfam match to PF01795 Methyltransf_5, score 409.5, E-value 4.2E-120 YP_001490248.1 Pfam match to PF00216 Bac_DNA_binding, score 143.2, E-value 6.4E-040 YP_001490249.1 Pfam match to PF00589 Phage_integrase, score 24.4, E-value 1.2E-006 YP_001490256.1 Pfam match to PF00270 DEAD, score 27.5, E-value 2.3E-007 YP_001490277.1 Pfam match to PF07022 Phage_CI_repr, score 21.8, E-value 1.8E-005 YP_001490278.1 Pfam match to PF02082 Rrf2, score 101.2, E-value 1.9E-030 YP_001490281.1 Pfam match to PF01266 DAO, score 50.6, E-value 3.7E-014 YP_001490283.1 Pfam match to PF00072 Response_reg, score 70.9, E-value 2.9E-021 YP_001490284.1 Pfam match to PF04509 CheC, score 28.7, E-value 1.9E-005 YP_001490285.1 Pfam matches to PF02518 HATPase_c, score 66.6, E-value 7.1E-017, and to PF00989 PAS, score 21.4, E-value 5.5E-006 YP_001490286.1 Pfam matches to PF00226 DnaJ, score 127.4, E-value 3.1E-037, and to PF01556 DnaJ_C, score 67.4, E-value 4.1E-017 YP_001490287.1 Pfam match to PF00376 MerR, score 42.3, E-value 6.8E-011 YP_001490288.1 Pfam match to PF00529 HlyD, score 28.9, E-value 2E-007 YP_001490289.1 Pfam match to PF00005 ABC_tran, score 173, E-value 6.8E-049 YP_001490290.1 Pfam match to PF01061 ABC2_membrane, score 85.3, E-value 1.7E-023 YP_001490291.1 Pfam match to PF01061 ABC2_membrane, score 117.5, E-value 1.8E-032 YP_001490292.1 Pfam match to PF04332 DUF475, score 282.4, E-value 8.2E-082 YP_001490293.1 Pfam match to PF05525 Branch_AA_trans, score 392.7, E-value 2.3E-117 YP_001490296.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001490297.1 Pfam match to PF01522 Polysacc_deac_1, score 66.6, E-value 1.7E-018 YP_001490298.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001490300.1 Pfam match to PF00561 Abhydrolase_1, score 43.6, E-value 5E-012 YP_001490301.1 Pfam matches to PF00593 TonB_dep_Rec, score 82.5, E-value 1.2E-021, and to PF07715 Plug, score 63.2, E-value 7.7E-016 YP_001490303.1 Pfam matches to PF00091 Tubulin, score 255, E-value 2.7E-075, and to PF03953 Tubulin_C, score 60.8, E-value 6E-017 YP_001490304.1 Pfam match to PF02491 FtsA, score 103, E-value 8E-028 YP_001490308.1 Pfam match to PF03960 ArsC, score 86.7, E-value 7E-019 YP_001490310.1 Pfam match to PF05016 Plasmid_stabil, score 40.2, E-value 2.6E-010 YP_001490313.1 Pfam match to PF01312 Bac_export_2, score 43.9, E-value 7E-013 YP_001490314.1 Pfam match to PF00005 ABC_tran, score 150, E-value 5.6E-042 YP_001490315.1 Pfam match to PF08020 DUF1706, score 256.7, E-value 4.5E-074 YP_001490317.1 Pfam matches to PF00702 Hydrolase, score 100.9, E-value 2E-028, and to PF08125 Mannitol_dh_C, score 27.5, E-value 2.8E-007 YP_001490319.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001490324.1 Pfam match to PF01155 HypA, score 168.2, E-value 1.9E-047 YP_001490325.1 Pfam matches to PF02769 AIRS_C, score 103.6, E-value 5.2E-028, and to PF00586 AIRS, score 100.6, E-value 4.2E-027 YP_001490327.1 Pfam match to PF03446 NAD_binding_2, score 259.5, E-value 6.1E-075 YP_001490328.1 Pfam match to PF07728 AAA_5, score 39.6, E-value 2.5E-011 YP_001490330.1 Pfam match to PF01924 HypD, score 696.6, E-value 1.7E-206 YP_001490331.1 Pfam match to PF01455 HupF_HypC, score 90.7, E-value 3.9E-024 YP_001490332.1 Pfam match to PF02492 cobW, score 191.4, E-value 3.1E-055 YP_001490334.1 Pfam match to PF00015 MCPsignal, score 145.6, E-value 1.2E-040 YP_001490335.1 Pfam match to PF02588 DUF161, score 61.4, E-value 2.6E-015 YP_001490336.1 Pfam match to PF03486 HI0933_like, score 402.1, E-value 7.2E-118 YP_001490337.1 Pfam match to PF05661 DUF808, score 281.5, E-value 1.5E-081 YP_001490340.1 Pfam match to PF04338 DUF481, score 37, E-value 1.1E-011 YP_001490343.1 Required for the synthesis of the thiazole moiety YP_001490346.1 Pfam match to PF07399 DUF1504, score 630.7, E-value 1.1E-186 YP_001490347.1 Pfam matches to PF01300 Sua5_yciO_yrdC, score 161.8, E-value 1.6E-045, and to PF07503 zf-HYPF, score 67.8, E-value 3.2E-017, and to PF00708 Acylphosphatase, score 30.1, E-value 2.4E-008 YP_001490349.1 Pfam match to PF01750 HycI, score 78.2, E-value 2.4E-020 YP_001490350.1 Pfam match to PF01292 Ni_hydr_CYTB, score 86.9, E-value 5.5E-023 YP_001490351.1 Pfam match to PF00374 NiFeSe_Hases, score 888.5, E-value 2.7E-264 YP_001490352.1 Pfam matches to PF08425 NiFe_dehyd_N, score 166.1, E-value 7.9E-047, and to PF01058 Oxidored_q6, score 6.3, E-value 1.3E-005 YP_001490353.1 Pfam match to PF04773 FecR, score 78.5, E-value 1.9E-020 YP_001490354.1 Pfam match to PF08281 Sigma70_r4_2, score 33.9, E-value 4.4E-009 YP_001490356.1 Pfam match to PF01750 HycI, score 68.4, E-value 4.1E-018 YP_001490358.1 Pfam match to PF00374 NiFeSe_Hases, score 863.9, E-value 7.3E-257 YP_001490359.1 Pfam matches to PF08425 NiFe_dehyd_N, score 140.7, E-value 3.7E-039, and to PF01058 Oxidored_q6, score 7.4, E-value 1E-005 YP_001490360.1 Pfam match to PF00374 NiFeSe_Hases, score -0.8, E-value 1.1E-014 YP_001490363.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001490365.1 Pfam matches to PF00990 GGDEF, score 151, E-value 3.3E-043, and to PF08448 PAS_4, score 24, E-value 4.9E-006 YP_001490366.1 Pfam match to PF01709 DUF28, score 342.7, E-value 5.6E-100 YP_001490367.1 Pfam match to PF04333 VacJ, score 232.5, E-value 8.6E-067 YP_001490368.1 Pfam match to PF05494 Tol_Tol_Ttg2, score 108, E-value 2.5E-029 YP_001490370.1 Pfam match to PF03641 Lysine_decarbox, score 162.4, E-value 1.1E-045 YP_001490371.1 Pfam match to PF00702 Hydrolase, score 94.5, E-value 1.3E-026 YP_001490372.1 Pfam match to PF08534 Redoxin, score 68.4, E-value 2.1E-017 YP_001490373.1 Pfam match to PF01323 DSBA, score 9.4, E-value 1.6E-005 YP_001490374.1 Pfam match to PF02600 DsbB, score 92.8, E-value 9.7E-025 YP_001490375.1 Pfam match to PF00535 Glycos_transf_2, score 78.2, E-value 4.8E-023 YP_001490376.1 Pfam matches to PF08281 Sigma70_r4_2, score 46.6, E-value 8.1E-013, and to PF04542 Sigma70_r2, score 27.3, E-value 4.9E-005 YP_001490377.1 Pfam match to PF04773 FecR, score 78.6, E-value 1.8E-020 YP_001490378.1 Pfam matches to PF00593 TonB_dep_Rec, score 84.9, E-value 2.3E-022, and to PF07715 Plug, score 71.6, E-value 2.2E-018, and to PF07660 STN, score 33, E-value 9.3E-007 YP_001490379.1 Pfam match to PF00990 GGDEF, score 183.5, E-value 4.8E-052 YP_001490380.1 Pfam match to PF01988 DUF125, score 93.5, E-value 5.8E-025 YP_001490381.1 Pfam match to PF02028 BCCT, score 772.5, E-value 2.4E-229 YP_001490382.1 Pfam matches to PF00999 Na_H_Exchanger, score 204.3, E-value 2.5E-058, and to PF02254 TrkA_N, score 53.1, E-value 1.1E-013 YP_001490384.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001490385.1 Pfam matches to PF01035 DNA_binding_1, score 119.1, E-value 1.1E-032, and to PF00165 HTH_AraC, score 56.9, E-value 6.1E-014 YP_001490386.1 Pfam match to PF00633 HHH, score 22.1, E-value 1.2E-005 YP_001490390.1 Pfam match to PF01243 Pyridox_oxidase, score 28.2, E-value 2.6E-005 YP_001490391.1 Pfam match to PF03594 BenE, score 592.5, E-value 3.5E-175 YP_001490392.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001490393.1 Pfam match to PF03473 MOSC, score 98.3, E-value 2.1E-026 YP_001490394.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001490395.1 Pfam match to PF03099 BPL_LipA_LipB, score 24.1, E-value 5.3E-006 YP_001490396.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001490397.1 Pfam matches to PF00198 2-oxoacid_dh, score 382, E-value 8.2E-112, and to PF00364 Biotin_lipoyl, score 62.8, E-value 1.1E-016, and to PF02817 E3_binding, score 65.2, E-value 1.9E-016, and to PF00364 Biotin_lipoyl, score 54.9, E-value 1.8E-014 YP_001490398.1 Pfam matches to PF07992 Pyr_redox_2, score 220.2, E-value 4.2E-063, and to PF02852 Pyr_redox_dim, score 164.9, E-value 1.9E-046 YP_001490399.1 Pfam match to PF00117 GATase, score 32.6, E-value 6.3E-008 YP_001490400.1 Pfam matches to PF00593 TonB_dep_Rec, score 90.8, E-value 3.8E-024, and to PF07715 Plug, score 72.1, E-value 1.6E-018, and to PF07660 STN, score 34, E-value 4.8E-007 YP_001490401.1 Pfam match to PF01263 Aldose_epim, score 71.2, E-value 2.2E-020 YP_001490402.1 Pfam match to PF00905 Transpeptidase, score 180.5, E-value 3.8E-051 YP_001490403.1 Pfam matches to PF00270 DEAD, score 244.2, E-value 2.6E-070, and to PF00271 Helicase_C, score 115.1, E-value 3.9E-038 YP_001490405.1 Pfam match to PF00145 DNA_methylase, score 475.9, E-value 4.5E-140 YP_001490407.1 Pfam match to PF01381 HTH_3, score 30.6, E-value 1.4E-007 YP_001490408.1 Pfam match to PF02624 YcaO, score 194.5, E-value 2.3E-055 YP_001490409.1 Pfam match to PF03625 DUF302, score 55.2, E-value 2E-013 YP_001490411.1 Pfam matches to PF08376 NIT, score 229.8, E-value 5.6E-066, and to PF00015 MCPsignal, score 163.4, E-value 5.5E-046 YP_001490412.1 Pfam match to PF00075 RnaseH, score 126.3, E-value 3E-037 YP_001490413.1 Pfam match to PF00682 HMGL-like, score 44.1, E-value 8.9E-012 YP_001490416.1 Pfam match to PF00817 IMS, score 111.8, E-value 1.9E-030 YP_001490417.1 Pfam matches to PF03453 MoeA_N, score 169.7, E-value 6.9E-048, and to PF00994 MoCF_biosynth, score 143.6, E-value 1.6E-041 YP_001490418.1 similar to NifS YP_001490419.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001490421.1 Pfam match to PF00037 Fer4, score 37.6, E-value 3.9E-008 YP_001490422.1 Pfam match to PF00384 Molybdopterin, score 142, E-value 2E-034 YP_001490427.1 Pfam match to PF02518 HATPase_c, score 79.5, E-value 9.7E-021 YP_001490428.1 Pfam match to PF00072 Response_reg, score 59.4, E-value 9.6E-018 YP_001490430.1 Pfam match to PF00403 HMA, score 52.2, E-value 1.6E-012 YP_001490431.1 similar to MerT YP_001490432.1 Pfam match to PF01841 Transglut_core, score 62.8, E-value 9.9E-016 YP_001490434.1 Pfam match to PF00037 Fer4, score 37.6, E-value 3.9E-008 YP_001490435.1 Pfam matches to PF00384 Molybdopterin, score 181.1, E-value 1.2E-051, and to PF01568 Molydop_binding, score 60.5, E-value 3.7E-016, and to PF04879 Molybdop_Fe4S4, score 62.3, E-value 1.4E-015, and to PF00384 Molybdopterin, score 43.1, E-value 2.1E-012 YP_001490437.1 Pfam matches to PF02769 AIRS_C, score 47.9, E-value 3.1E-011, and to PF00586 AIRS, score 20.2, E-value 2.7E-005 YP_001490444.1 Pfam match to PF00959 Phage_lysozyme, score 28.2, E-value 2.6E-005 YP_001490446.1 Pfam match to PF08238 Sel1, score 54, E-value 4.5E-013 YP_001490447.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001490448.1 Pfam match to PF00009 GTP_EFTU, score 116.5, E-value 7.2E-032 YP_001490455.1 Pfam matches to PF02518 HATPase_c, score 56.5, E-value 8.3E-014, and to PF08269 Cache_2, score 39, E-value 1.5E-008 YP_001490456.1 Pfam match to PF03358 FMN_red, score 27.2, E-value 1.6E-007 YP_001490457.1 Pfam match to PF02562 PhoH, score 23, E-value 3.7E-006 YP_001490459.1 Pfam matches to PF00563 EAL, score 200.3, E-value 4.3E-057, and to PF00989 PAS, score 44.3, E-value 6.6E-013, and to PF00990 GGDEF, score -16.3, E-value 7.7E-006 YP_001490460.1 Pfam match to PF01243 Pyridox_oxidase, score 92.7, E-value 1E-024 YP_001490461.1 Pfam matches to PF00990 GGDEF, score 207.3, E-value 3.3E-059, and to PF08447 PAS_3, score 33.5, E-value 1.3E-008 YP_001490462.1 Pfam matches to PF00270 DEAD, score 234.8, E-value 1.7E-067, and to PF00271 Helicase_C, score 104.1, E-value 1.9E-034, and to PF03880 DbpA, score 31.3, E-value 1.3E-006 YP_001490466.1 molecular chaperone YP_001490467.1 Pfam match to PF00141 peroxidase, score 358.7, E-value 8.7E-105 YP_001490469.1 Pfam match to PF00023 Ank, score 37.6, E-value 1.6E-009 YP_001490470.1 Pfam match to PF02470 MCE, score 78.6, E-value 1.8E-020 YP_001490471.1 Pfam match to PF01152 Bac_globin, score 29.6, E-value 2.1E-007 YP_001490472.1 Pfam matches to PF00563 EAL, score 264, E-value 2.8E-076, and to PF00990 GGDEF, score 213, E-value 6.4E-061 YP_001490475.1 Pfam match to PF00892 DUF6, score 64.7, E-value 2.8E-016 YP_001490476.1 Pfam match to PF04073 YbaK, score 205.6, E-value 1.1E-058 YP_001490480.1 Pfam match to PF01965 DJ-1_PfpI, score 50.3, E-value 5.8E-012 YP_001490482.1 Pfam matches to PF00593 TonB_dep_Rec, score 92.1, E-value 1.5E-024, and to PF07715 Plug, score 75.7, E-value 1.3E-019 YP_001490484.1 Pfam match to PF05534 HicB, score 70.8, E-value 2.4E-019 YP_001490485.1 Pfam match to PF04773 FecR, score 70.8, E-value 4E-018 YP_001490486.1 Pfam matches to PF08281 Sigma70_r4_2, score 49, E-value 1.7E-013, and to PF04542 Sigma70_r2, score 36.8, E-value 6.9E-008 YP_001490487.1 Pfam match to PF00491 Arginase, score 70.5, E-value 4.8E-018 YP_001490488.1 Pfam match to PF00682 HMGL-like, score 273.4, E-value 4E-079 YP_001490489.1 Pfam match to PF00165 HTH_AraC, score 47.4, E-value 4.5E-011 YP_001490490.1 Pfam match to PF02452 PemK, score 36.5, E-value 8.2E-008 YP_001490491.1 Pfam match to PF04014 SpoVT_AbrB, score 30.9, E-value 4E-006 YP_001490492.1 Pfam match to PF00165 HTH_AraC, score 35.2, E-value 2E-007 YP_001490493.1 Pfam matches to PF00593 TonB_dep_Rec, score 93.6, E-value 5.4E-025, and to PF07715 Plug, score 78.4, E-value 2E-020 YP_001490494.1 Pfam matches to PF02777 Sod_Fe_C, score 215.5, E-value 8.7E-072, and to PF00081 Sod_Fe_N, score 157.7, E-value 2.8E-044 YP_001490495.1 Pfam match to PF00924 MS_channel, score 127.3, E-value 3.9E-035 YP_001490496.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001490497.1 Pfam match to PF06555 DUF1121, score 105.8, E-value 1.1E-028 YP_001490499.1 Pfam match to PF00206 Lyase_1, score 463.1, E-value 3.2E-136 YP_001490500.1 Pfam match to PF00072 Response_reg, score 93.7, E-value 3E-028 YP_001490501.1 Pfam match to PF02518 HATPase_c, score 78.4, E-value 2.1E-020 YP_001490502.1 Pfam match to PF01235 Na_Ala_symp, score 544.4, E-value 1.1E-160 YP_001490503.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001490504.1 Pfam match to PF00698 Acyl_transf_1, score -7.6, E-value 1.1E-009 YP_001490505.1 Pfam match to PF00254 FKBP_C, score 32, E-value 1.9E-008 YP_001490507.1 Pfam match to PF00691 OmpA, score 94.9, E-value 2.2E-025 YP_001490508.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001490510.1 Pfam match to PF02472 ExbD, score 39.7, E-value 9.1E-009 YP_001490511.1 Pfam match to PF01618 MotA_ExbB, score 95, E-value 2.1E-025 YP_001490512.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001490513.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001490514.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001490515.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001490516.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The delta subunit is part of the catalytic core of the ATP synthase complex YP_001490517.1 Pfam match to PF00430 ATP-synt_B, score 38.7, E-value 4E-004 YP_001490518.1 Pfam match to PF00430 ATP-synt_B, score 30.8, E-value 4.3E-006 YP_001490519.1 Pfam match to PF02195 ParBc, score 115.7, E-value 1.2E-031 YP_001490520.1 Pfam match to PF01656 CbiA, score 189.8, E-value 6.1E-054 YP_001490521.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001490523.1 Pfam match to PF03547 Auxin_eff, score 74.6, E-value 6.4E-023 YP_001490524.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001490525.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001490526.1 Pfam matches to PF01018 GTP1_OBG, score 257.2, E-value 3.2E-074, and to PF01926 MMR_HSR1, score 127, E-value 4.8E-035 YP_001490527.1 involved in the peptidyltransferase reaction during translation YP_001490528.1 Pfam match to PF00829 Ribosomal_L21p, score 132.1, E-value 1.4E-036 YP_001490529.1 Pfam matches to PF01807 zf-CHC2, score 189.2, E-value 9.2E-054, and to PF08275 Toprim_N, score 153.4, E-value 5.3E-043, and to PF01751 Toprim, score 70.8, E-value 3.9E-018 YP_001490531.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001490532.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001490534.1 Pfam match to PF01435 Peptidase_M48, score 95.8, E-value 2.7E-028 YP_001490536.1 Pfam match to PF00300 PGAM, score 68.6, E-value 1.9E-017 YP_001490538.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001490540.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001490541.1 Pfam match to PF01809 DUF37, score 80.4, E-value 5.2E-021 YP_001490542.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001490543.1 Pfam matches to PF07724 AAA_2, score 376.3, E-value 4.4E-110, and to PF00004 AAA, score 85.3, E-value 1.3E-025, and to PF02861 Clp_N, score 41.6, E-value 2.4E-009 YP_001490544.1 Pfam match to PF01351 RNase_HII, score 174, E-value 3.5E-049 YP_001490545.1 Pfam match to PF01910 DUF77, score 60.8, E-value 4.2E-015 YP_001490546.1 Pfam match to PF03976 PPK2, score 383.4, E-value 3E-112 YP_001490548.1 Pfam match to PF01625 PMSR, score 228.5, E-value 1.3E-065 YP_001490549.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; a fusion protein of this enzyme with MsrA and thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001490550.1 Pfam match to PF01557 FAA_hydrolase, score 78.6, E-value 1.8E-020 YP_001490551.1 Pfam match to PF06948 DUF1291, score 21.8, E-value 8.1E-007 YP_001490553.1 Pfam match to PF00202 Aminotran_3, score 446.9, E-value 2.4E-131 YP_001490554.1 Pfam match to PF02518 HATPase_c, score 75, E-value 2.2E-019 YP_001490555.1 involved in de novo purine biosynthesis YP_001490556.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001490558.1 Pfam match to PF01551 Peptidase_M23, score 168.6, E-value 4.4E-054 YP_001490559.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001490560.1 Pfam match to PF01544 CorA, score 180.5, E-value 3.9E-051 YP_001490561.1 Pfam match to PF00482 GSPII_F, score 54.4, E-value 3.3E-013 YP_001490562.1 Pfam match to PF00437 GSPII_E, score 252.2, E-value 1E-072 YP_001490563.1 Pfam match to PF03692 UPF0153, score 40.4, E-value 5.7E-009 YP_001490564.1 Pfam match to PF00717 Peptidase_S24, score 40.3, E-value 6.1E-009 YP_001490567.1 Pfam match to PF02086 MethyltransfD12, score 100.5, E-value 4.6E-027 YP_001490568.1 Pfam match to PF05954 Phage_GPD, score 140.1, E-value 5.6E-039 YP_001490576.1 Pfam match to PF02413 Caudo_TAP, score 20.8, E-value 6.9E-006 YP_001490579.1 Pfam match to PF04865 Baseplate_J, score 79.6, E-value 9.1E-021 YP_001490580.1 Pfam match to PF04965 GPW_gp25, score 26.4, E-value 1E-007 YP_001490581.1 Pfam match to PF04717 Phage_base_V, score 63.3, E-value 7.1E-016 YP_001490592.1 Pfam match to PF06074 DUF935, score 26.3, E-value 1.5E-007 YP_001490593.1 Pfam match to PF04233 Phage_Mu_F, score 136.8, E-value 5.2E-038 YP_001490607.1 Pfam match to PF00665 rve, score 47.4, E-value 9.5E-013 YP_001490609.1 Pfam match to PF00717 Peptidase_S24, score 47.6, E-value 3.9E-011 YP_001490613.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001490615.1 Pfam match to PF01078 Mg_chelatase, score 348, E-value 1.5E-101 YP_001490617.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001490618.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001490619.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001490620.1 Pfam match to PF03976 PPK2, score 391, E-value 1.6E-114 YP_001490621.1 Pfam match to PF03976 PPK2, score 543.6, E-value 1.9E-160 YP_001490622.1 Pfam match to PF00278 Orn_DAP_Arg_deC, score 103.5, E-value 7.1E-029 YP_001490623.1 Pfam match to PF03435 Saccharop_dh, score 564.4, E-value 1E-166 YP_001490624.1 Pfam match to PF00589 Phage_integrase, score 60.2, E-value 6E-015 YP_001490632.1 Pfam match to PF02463 SMC_N, score -68.5, E-value 1.1E-006 YP_001490633.1 Pfam match to PF01420 Methylase_S, score 123.1, E-value 7.3E-034 YP_001490634.1 Pfam match to PF02384 N6_Mtase, score 52.8, E-value 9.4E-016 YP_001490635.1 Pfam match to PF00226 DnaJ, score 22.5, E-value 4.2E-006 YP_001490638.1 Pfam match to PF03734 ErfK_YbiS_YhnG, score 32.6, E-value 9.9E-007 YP_001490640.1 Pfam match to PF01053 Cys_Met_Meta_PP, score 370.5, E-value 2.4E-108 YP_001490641.1 Pfam match to PF01053 Cys_Met_Meta_PP, score -144.4, E-value 4.7E-011 YP_001490642.1 Pfam matches to PF00072 Response_reg, score 114.9, E-value 9.6E-035, and to PF00486 Trans_reg_C, score 55.8, E-value 1.3E-013 YP_001490643.1 Pfam match to PF00015 MCPsignal, score 163.7, E-value 4.4E-046 YP_001490645.1 Pfam matches to PF01966 HD, score 104.9, E-value 2.1E-028, and to PF08447 PAS_3, score 82.2, E-value 1.5E-021, and to PF00072 Response_reg, score 67, E-value 4.5E-020, and to PF08447 PAS_3, score 48.4, E-value 1E-012 YP_001490646.1 Pfam match to PF00015 MCPsignal, score 163.7, E-value 4.4E-046 YP_001490647.1 Pfam match to PF02518 HATPase_c, score 77.5, E-value 4E-020 YP_001490648.1 Pfam match to PF03547 Auxin_eff, score 54, E-value 1.2E-016 YP_001490654.1 Pfam match to PF00583 Acetyltransf_1, score 71.1, E-value 3.2E-018 YP_001490655.1 Pfam match to PF03824 NicO, score 42.1, E-value 1.8E-009 YP_001490656.1 Pfam match to PF01297 SBP_bac_9, score 244.7, E-value 1.8E-070 YP_001490657.1 Pfam match to PF01475 FUR, score 34.5, E-value 5.9E-008 YP_001490658.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001490659.1 Pfam match to PF03150 CCP_MauG, score 169.3, E-value 8.6E-048 YP_001490660.1 Pfam match to PF01598 Sterol_desat, score 29.4, E-value 7.4E-008 YP_001490662.1 Pfam match to PF06537 DUF1111, score 480.2, E-value 2.3E-141 YP_001490665.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001490666.1 Pfam matches to PF00015 MCPsignal, score 132, E-value 1.5E-036, and to PF02743 Cache_1, score 80.4, E-value 5.2E-021 YP_001490667.1 Pfam match to PF01594 UPF0118, score 158.1, E-value 2E-044 YP_001490668.1 Pfam match to PF00520 Ion_trans, score 145.1, E-value 1.7E-040 YP_001490672.1 Pfam match to PF08543 Phos_pyr_kin, score 324.9, E-value 1.3E-094 YP_001490673.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001490677.1 Pfam match to PF02518 HATPase_c, score 83.9, E-value 4.5E-022 YP_001490678.1 Pfam match to PF00072 Response_reg, score 84.2, E-value 2.4E-025 YP_001490679.1 Pfam match to PF01035 DNA_binding_1, score 124.5, E-value 2.7E-034 YP_001490680.1 Pfam matches to PF02878 PGM_PMM_I, score 105.7, E-value 1.3E-028, and to PF02879 PGM_PMM_II, score 72, E-value 1.7E-018, and to PF02880 PGM_PMM_III, score 43.1, E-value 8.6E-010 YP_001490681.1 Pfam match to PF00795 CN_hydrolase, score 53.1, E-value 8.5E-013 YP_001490685.1 Pfam match to PF00258 Flavodoxin_1, score 148.3, E-value 1.9E-041 YP_001490686.1 Pfam match to PF01475 FUR, score 187.5, E-value 2.9E-053 YP_001490688.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001490689.1 Pfam match to PF00290 Trp_syntA, score 190.2, E-value 4.6E-054 YP_001490690.1 Pfam match to PF00654 Voltage_CLC, score 140.3, E-value 4.8E-039 YP_001490691.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001490692.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001490693.1 Pfam match to PF01594 UPF0118, score 164.2, E-value 3.1E-046 YP_001490695.1 Pfam match to PF04055 Radical_SAM, score 52.4, E-value 1.4E-012 YP_001490696.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001490697.1 Pfam match to PF03350 UPF0114, score 146.2, E-value 8E-041 YP_001490698.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001490699.1 negatively supercoils closed circular double-stranded DNA YP_001490701.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001490702.1 Pfam matches to PF02254 TrkA_N, score 50.1, E-value 7E-013, and to PF02080 TrkA_C, score 40.5, E-value 5.4E-009 YP_001490703.1 required for 70S ribosome assembly YP_001490705.1 Possible pseudogene/truncated protein. G:A transition (Met:Ile) at bp 1795888 results in a potential start codon shift to bp 1796039. N-terminal sequence downstream of ly mutated start codon at 1795886 corresponds to N-terminal sequences of similar protein in P. haloplanktis. Good RBS present at bp 1795874-1795879. YP_001490706.1 Pfam match to PF01370 Epimerase, score 109.1, E-value 1.1E-029 YP_001490707.1 Pfam matches to PF00294 PfkB, score 126.7, E-value 5.8E-035, and to PF01467 CTP_transf_2, score 57.6, E-value 3.7E-016 YP_001490708.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001490709.1 Pfam match to PF00884 Sulfatase, score 128.1, E-value 2.3E-035 YP_001490710.1 Pfam match to PF01075 Glyco_transf_9, score 115.2, E-value 1.3E-032 YP_001490714.1 Pfam match to PF00884 Sulfatase, score 117.6, E-value 3.3E-032 YP_001490717.1 Pfam match to PF03062 MBOAT, score 262.2, E-value 9.6E-076 YP_001490718.1 Pfam match to PF00534 Glycos_transf_1, score 153.8, E-value 4.1E-043 YP_001490719.1 Pfam match to PF00535 Glycos_transf_2, score 49.9, E-value 1.3E-014 YP_001490720.1 Pfam match to PF00534 Glycos_transf_1, score 88.9, E-value 3.2E-024 YP_001490721.1 Pfam match to PF00535 Glycos_transf_2, score 119, E-value 3.5E-035 YP_001490723.1 Pfam match to PF00534 Glycos_transf_1, score 78.6, E-value 2.4E-021 YP_001490724.1 Pfam match to PF04932 Wzy_C, score 38, E-value 3E-008 YP_001490725.1 Pfam match to PF01041 DegT_DnrJ_EryC1, score 270.9, E-value 2.3E-078 YP_001490726.1 Pfam match to PF01370 Epimerase, score 271.8, E-value 1.2E-078 YP_001490727.1 Pfam match to PF00483 NTP_transferase, score 377.5, E-value 1.9E-110 YP_001490728.1 Pfam match to PF00884 Sulfatase, score 85.3, E-value 2.4E-023 YP_001490729.1 Pfam match to PF01219 DAGK_prokar, score 100.7, E-value 3.9E-027 YP_001490731.1 Pfam match to PF03279 Lip_A_acyltrans, score 126.8, E-value 5.4E-035 YP_001490732.1 Pfam match to PF01075 Glyco_transf_9, score 139.5, E-value 1.6E-039 YP_001490733.1 Pfam match to PF02541 Ppx-GppA, score 225.4, E-value 1.1E-064 YP_001490734.1 Pfam match to PF00037 Fer4, score 22.6, E-value 9.1E-005 YP_001490735.1 Pfam match to PF00459 Inositol_P, score 31.9, E-value 1.3E-008 YP_001490736.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001490737.1 Pfam matches to PF01645 Glu_synthase, score 688.8, E-value 3.6E-204, and to PF00310 GATase_2, score 484.4, E-value 1.2E-142, and to PF04898 Glu_syn_central, score 323.9, E-value 2.7E-094, and to PF01493 GXGXG, score 280.5, E-value 2.9E-081 YP_001490740.1 Pfam matches to PF00015 MCPsignal, score 152.6, E-value 9.6E-043, and to PF02743 Cache_1, score 69.3, E-value 1.1E-017 YP_001490741.1 Pfam match to PF00015 MCPsignal, score 160.5, E-value 3.9E-045 YP_001490743.1 Pfam matches to PF00263 Secretin, score 162.6, E-value 9.2E-046, and to PF03958 Secretin_N, score 34, E-value 9.5E-009 YP_001490744.1 Pfam match to PF01205 UPF0029, score 171.8, E-value 1.6E-048 YP_001490745.1 Pfam matches to PF01479 S4, score 38, E-value 3E-008, and to PF01728 FtsJ, score -14.9, E-value 1.1E-005 YP_001490746.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001490747.1 Pfam match to PF08241 Methyltransf_11, score 43.6, E-value 6E-010 YP_001490748.1 Pfam match to PF00578 AhpC-TSA, score 14.5, E-value 8.7E-013 YP_001490750.1 Pfam matches to PF02913 FAD-oxidase_C, score 290.5, E-value 2.9E-084, and to PF01565 FAD_binding_4, score 198.5, E-value 1.4E-056 YP_001490751.1 Pfam match to PF03631 Ribonuclease_BN, score 79.6, E-value 3.3E-023 YP_001490753.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001490754.1 Pfam match to PF00892 DUF6, score 81.6, E-value 2.2E-021 YP_001490755.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001490756.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001490757.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001490758.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001490759.1 Pfam match to PF00005 ABC_tran, score 109.5, E-value 8.9E-030 YP_001490761.1 Pfam match to PF04023 FeoA, score 79, E-value 1.3E-020 YP_001490762.1 Pfam matches to PF01926 MMR_HSR1, score 126.5, E-value 6.6E-035, and to PF02421 FeoB_N, score 85.3, E-value 1.7E-022, and to PF07670 Gate, score 60.4, E-value 1.1E-015, and to PF07664 FeoB_C, score 55.5, E-value 1.7E-013, and to PF07670 Gate, score 51.5, E-value 2.7E-013 YP_001490767.1 Pfam matches to PF00122 E1-E2_ATPase, score 211.3, E-value 7.2E-064, and to PF00702 Hydrolase, score 92.9, E-value 3.8E-026, and to PF00403 HMA, score 26.9, E-value 6.5E-005 YP_001490768.1 Pfam match to PF01022 HTH_5, score 58.5, E-value 2.9E-016 YP_001490769.1 Pfam matches to PF00593 TonB_dep_Rec, score 92, E-value 1.7E-024, and to PF07715 Plug, score 48.8, E-value 1.6E-011 YP_001490771.1 Pfam match to PF00873 ACR_tran, score 79.4, E-value 1.1E-020 YP_001490774.1 Pfam match to PF00313 CSD, score 104.9, E-value 2.1E-028 YP_001490776.1 Pfam matches to PF00072 Response_reg, score 90.4, E-value 3.1E-027, and to PF00486 Trans_reg_C, score 43.3, E-value 7.5E-010 YP_001490777.1 Pfam matches to PF07695 7TMR-DISM_7TM, score 62.8, E-value 1E-015, and to PF02518 HATPase_c, score 47.1, E-value 5.2E-011 YP_001490779.1 Pfam match to PF01051 Rep_3, score 110.7, E-value 4E-030 YP_001490782.1 Pfam match to PF00578 AhpC-TSA, score 325.3, E-value 9.9E-095 YP_001490783.1 Pfam match to PF00085 Thioredoxin, score 139.3, E-value 9.7E-039 YP_001490784.1 Pfam match to PF03795 YCII, score 46.8, E-value 6.6E-011 YP_001490786.1 Pfam matches to PF04997 RNA_pol_Rpb1_1, score 459.7, E-value 3.3E-135, and to PF00623 RNA_pol_Rpb1_2, score 282.5, E-value 7.3E-082, and to PF04998 RNA_pol_Rpb1_5, score 267, E-value 3.3E-077, and to PF04983 RNA_pol_Rpb1_3, score 166.3, E-value 1.3E-049, and to PF05000 RNA_pol_Rpb1_4, score 114, E-value 4E-031 YP_001490787.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001490788.1 Pfam match to PF00542 Ribosomal_L12, score 130.9, E-value 3.2E-036 YP_001490789.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001490790.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001490791.1 Pfam matches to PF03946 Ribosomal_L11_N, score 124.3, E-value 3.2E-034, and to PF00298 Ribosomal_L11, score 73.2, E-value 7.7E-019 YP_001490792.1 Modulates Rho-dependent transcription termination YP_001490793.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001490794.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001490795.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001490796.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001490797.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001490798.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001490799.1 Pfam match to PF00005 ABC_tran, score 143.7, E-value 4.4E-040 YP_001490800.1 Pfam matches to PF00912 Transgly, score 281.2, E-value 1.9E-081, and to PF00905 Transpeptidase, score 115.2, E-value 1.7E-031 YP_001490801.1 Pfam matches to PF00120 Gln-synt_C, score 540.9, E-value 1.2E-159, and to PF03951 Gln-synt_N, score 134.6, E-value 2.5E-037 YP_001490802.1 Pfam match to PF02811 PHP, score 66.9, E-value 2.2E-019 YP_001490804.1 Pfam match to PF02597 ThiS, score 45.3, E-value 1.9E-010 YP_001490805.1 Pfam match to PF02621 DUF178, score 94.1, E-value 3.8E-025 YP_001490806.1 Pfam match to PF02673 BacA, score 345.1, E-value 1.1E-100 YP_001490807.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001490808.1 Pfam match to PF00905 Transpeptidase, score 248.9, E-value 9.6E-072 YP_001490809.1 Pfam match to PF01098 FTSW_RODA_SPOVE, score 272, E-value 1.1E-078 YP_001490810.1 Pfam match to PF00160 Pro_isomerase, score 160.6, E-value 3.6E-045 YP_001490811.1 Pfam match to PF00034 Cytochrom_C, score 32.6, E-value 1.3E-006 YP_001490812.1 Pfam matches to PF07724 AAA_2, score 284, E-value 2.6E-082, and to PF00004 AAA, score 52.3, E-value 1.3E-015, and to PF02861 Clp_N, score 32.2, E-value 1.6E-006 YP_001490813.1 Pfam match to PF02617 ClpS, score 149.4, E-value 8.4E-042 YP_001490817.1 Pfam matches to PF00501 AMP-binding, score 380.6, E-value 2.2E-111, and to PF03328 HpcH_HpaI, score 82.5, E-value 7.9E-023 YP_001490818.1 Pfam match to PF01575 MaoC_dehydratas, score 27.2, E-value 1.3E-007 YP_001490820.1 Pfam matches to PF05681 Fumerase, score 485.6, E-value 5.4E-143, and to PF05683 Fumerase_C, score 326.2, E-value 5.4E-095 YP_001490822.1 Pfam match to PF00015 MCPsignal, score 122, E-value 1.5E-033 YP_001490823.1 Pfam match to PF02040 ArsB, score 642.1, E-value 4.1E-190 YP_001490824.1 Pfam match to PF01022 HTH_5, score 43.4, E-value 7.8E-012 YP_001490826.1 Pfam match to PF03773 DUF318, score 246.7, E-value 4.5E-071 YP_001490827.1 Pfam match to PF01451 LMWPc, score 86.9, E-value 5.7E-023 YP_001490829.1 Pfam match to PF07690 MFS_1, score 91.6, E-value 1.8E-025 YP_001490830.1 membrane protein involved in the flagellar export apparatus YP_001490832.1 involved in type III protein export during flagellum assembly YP_001490834.1 Pfam match to PF01312 Bac_export_2, score 394.4, E-value 1.6E-115 YP_001490835.1 Pfam match to PF01311 Bac_export_1, score 72.3, E-value 1.4E-018 YP_001490838.1 Pfam match to PF02049 FliE, score 64.8, E-value 2.5E-016 YP_001490840.1 Pfam match to PF01656 CbiA, score 57.4, E-value 4.2E-014 YP_001490841.1 Pfam match to PF00448 SRP54, score 115.1, E-value 1.8E-031 YP_001490845.1 Pfam match to PF01052 SpoA, score 66.7, E-value 6.6E-017 YP_001490847.1 Pfam match to PF00515 TPR_1, score 28, E-value 3E-005 YP_001490849.1 Pfam matches to PF06429 DUF1078, score 64.4, E-value 3.4E-016, and to PF00460 Flg_bb_rod, score 41.1, E-value 3.4E-009 YP_001490850.1 Pfam matches to PF06429 DUF1078, score 50.3, E-value 6E-012, and to PF00460 Flg_bb_rod, score 28.8, E-value 1.7E-005 YP_001490851.1 Pfam match to PF03963 FlgD, score 46.8, E-value 6.6E-011 YP_001490852.1 Pfam match to PF01052 SpoA, score 63.5, E-value 6.1E-016 YP_001490854.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001490855.1 Pfam matches to PF01514 YscJ_FliF, score 116.6, E-value 6.7E-032, and to PF08345 YscJ_FliF_C, score 105.2, E-value 1.7E-028 YP_001490856.1 Pfam match to PF00460 Flg_bb_rod, score 29.2, E-value 9.4E-007 YP_001490857.1 Pfam match to PF00460 Flg_bb_rod, score 24, E-value 2.4E-005 YP_001490859.1 Pfam match to PF00072 Response_reg, score 138.9, E-value 4.3E-042 YP_001490860.1 Pfam matches to PF06429 DUF1078, score 75.9, E-value 1.2E-019, and to PF00460 Flg_bb_rod, score 56.7, E-value 6.9E-014 YP_001490863.1 Pfam matches to PF01782 RimM, score 54.8, E-value 2.7E-013, and to PF05239 PRC, score 34.1, E-value 4.3E-007 YP_001490865.1 Pfam match to PF00886 Ribosomal_S16, score 121.7, E-value 1.9E-033 YP_001490866.1 Pfam matches to PF00448 SRP54, score 338.2, E-value 1.3E-098, and to PF02978 SRP_SPB, score 160.3, E-value 4.5E-045, and to PF02881 SRP54_N, score 46.6, E-value 7.9E-011 YP_001490867.1 Pfam match to PF00849 PseudoU_synth_2, score 111.5, E-value 2.2E-030 YP_001490868.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001490869.1 Pfam match to PF02591 DUF164, score 152.1, E-value 1.4E-042 YP_001490870.1 Pfam match to PF01784 NIF3, score 193.2, E-value 5.6E-055 YP_001490871.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001490872.1 Pfam match to PF00462 Glutaredoxin, score 31.8, E-value 1.1E-008 YP_001490873.1 Pfam match to PF00731 AIRC, score 214.4, E-value 2.4E-061 YP_001490875.1 Pfam match to PF01136 Peptidase_U32, score 357.2, E-value 2.4E-104 YP_001490876.1 Pfam matches to PF00015 MCPsignal, score 133.3, E-value 6E-037, and to PF08269 Cache_2, score 119.7, E-value 7.8E-033, and to PF00672 HAMP, score 43.1, E-value 8.8E-010 YP_001490877.1 Pfam match to PF02463 SMC_N, score -52.7, E-value 7.5E-008 YP_001490878.1 Pfam match to PF01513 NAD_kinase, score 232.3, E-value 9.4E-067 YP_001490879.1 Pfam matches to PF00009 GTP_EFTU, score 377.4, E-value 2.1E-110, and to PF03764 EFG_IV, score 223.9, E-value 3.2E-064, and to PF00679 EFG_C, score 177.9, E-value 2.3E-050, and to PF03144 GTP_EFTU_D2, score 71.7, E-value 2.2E-018 YP_001490880.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001490881.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001490882.1 Pfam match to PF00561 Abhydrolase_1, score 41.1, E-value 2.5E-011 YP_001490883.1 Pfam match to PF07690 MFS_1, score 161.4, E-value 2.2E-045 YP_001490884.1 Pfam matches to PF00593 TonB_dep_Rec, score 110.2, E-value 5.3E-030, and to PF07715 Plug, score 92.1, E-value 1.5E-024 YP_001490886.1 Pfam match to PF05940 NnrS, score -13.7, E-value 9.1E-010 YP_001490887.1 Pfam match to PF00005 ABC_tran, score 135.8, E-value 1.1E-037 YP_001490888.1 Pfam match to PF00528 BPD_transp_1, score 44.5, E-value 3.2E-010 YP_001490891.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001490892.1 Pfam match to PF01547 SBP_bac_1, score 57, E-value 5.7E-014 YP_001490894.1 Pfam match to PF00005 ABC_tran, score 208.9, E-value 1.1E-059 YP_001490895.1 Pfam match to PF00165 HTH_AraC, score 37.8, E-value 3.3E-008 YP_001490896.1 Pfam matches to PF00593 TonB_dep_Rec, score 104.3, E-value 3.3E-028, and to PF07715 Plug, score 68.3, E-value 2.3E-017 YP_001490900.1 Pfam matches to PF01077 NIR_SIR, score 147.2, E-value 3.9E-041, and to PF03460 NIR_SIR_ferr, score 39.1, E-value 1.4E-008, and to PF01077 NIR_SIR, score 35.8, E-value 1.4E-007 YP_001490903.1 Pfam match to PF07366 SnoaL, score 89.4, E-value 1E-023 YP_001490904.1 Pfam match to PF00575 S1, score 76.7, E-value 6.6E-020 YP_001490906.1 Pfam match to PF01042 Ribonuc_L-PSP, score 209, E-value 9.8E-060 YP_001490907.1 Pfam match to PF00293 NUDIX, score 62.2, E-value 1.5E-015 YP_001490908.1 Pfam matches to PF06445 AraC_E_bind, score 89.9, E-value 7.2E-024, and to PF00165 HTH_AraC, score 38, E-value 3E-008 YP_001490909.1 Pfam match to PF00155 Aminotran_1_2, score 43.6, E-value 4.7E-012 YP_001490911.1 similar to DedA YP_001490912.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001490913.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001490915.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001490916.1 Pfam match to PF00291 PALP, score 266.2, E-value 6.1E-077 YP_001490917.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001490918.1 Pfam match to PF02581 TMP-TENI, score 38.7, E-value 7.9E-013 YP_001490919.1 Pfam match to PF05538 Campylo_MOMP, score 58.3, E-value 3.4E-017 YP_001490920.1 Pfam match to PF02152 FolB, score 72.1, E-value 1.6E-018 YP_001490921.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001490922.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001490923.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001490924.1 Pfam matches to PF01368 DHH, score 110.4, E-value 3.3E-032, and to PF02272 DHHA1, score 38.9, E-value 1.6E-008 YP_001490925.1 Pfam match to PF01551 Peptidase_M23, score 89, E-value 1.9E-028 YP_001490926.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001490928.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001490929.1 Pfam match to PF04296 DUF448, score 26.2, E-value 4.8E-007 YP_001490930.1 Pfam matches to PF00009 GTP_EFTU, score 160.1, E-value 5.3E-045, and to PF04760 IF2_N, score 66.2, E-value 9.7E-017, and to PF03144 GTP_EFTU_D2, score 43.4, E-value 7.1E-010, and to PF04760 IF2_N, score 39.1, E-value 1.4E-008, and to PF03144 GTP_EFTU_D2, score 30.9, E-value 4.1E-006 YP_001490931.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001490932.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001490933.1 Pfam match to PF00383 dCMP_cyt_deam_1, score 117.5, E-value 3.5E-032 YP_001490934.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001490935.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001490936.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001490937.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001490938.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001490939.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001490940.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001490941.1 Pfam match to PF01230 HIT, score 125.2, E-value 1.7E-034 YP_001490942.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001490943.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001490944.1 carries the fatty acid chain in fatty acid biosynthesis YP_001490945.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001490948.1 Pfam match to PF06508 ExsB, score 289, E-value 2.1E-085 YP_001490950.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001490952.1 Pfam matches to PF00033 Cytochrom_B_N, score 223, E-value 1.2E-069, and to PF00032 Cytochrom_B_C, score 37.1, E-value 5.6E-010 YP_001490953.1 Pfam match to PF00355 Rieske, score 35.7, E-value 1.5E-007 YP_001490954.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001490955.1 Pfam match to PF00696 AA_kinase, score 163.6, E-value 4.6E-046 YP_001490956.1 Pfam match to PF00580 UvrD-helicase, score 88.5, E-value 3.1E-024 YP_001490958.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001490967.1 CcoO; FixO YP_001490968.1 CcoN; FixN YP_001490969.1 Pfam match to PF01668 SmpB, score 134.8, E-value 2.2E-037 YP_001490970.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis YP_001490971.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001490972.1 Pfam match to PF00580 UvrD-helicase, score 578.8, E-value 4.9E-171 YP_001490973.1 Pfam matches to PF00126 HTH_1, score 70.6, E-value 4.5E-018, and to PF03466 LysR_substrate, score 44, E-value 4.8E-010 YP_001490974.1 Pfam match to PF04055 Radical_SAM, score 33.8, E-value 5.6E-007 YP_001490975.1 Pfam matches to PF00310 GATase_2, score 64.7, E-value 1.2E-020, and to PF00156 Pribosyltran, score 42.6, E-value 1.2E-009 YP_001490976.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001490977.1 Pfam match to PF07992 Pyr_redox_2, score 142.8, E-value 8.4E-040 YP_001490978.1 Pfam match to PF00085 Thioredoxin, score 138.1, E-value 2.1E-038 YP_001490979.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001490980.1 Pfam match to PF04402 DUF541, score 145.8, E-value 1E-040 YP_001490981.1 Pfam match to PF07690 MFS_1, score 126.7, E-value 6.1E-035 YP_001490984.1 Pfam matches to PF00512 HisKA, score 41.2, E-value 3.2E-009, and to PF02518 HATPase_c, score 26.2, E-value 5.5E-007, and to PF00672 HAMP, score 32.6, E-value 1.3E-006 YP_001490985.1 Pfam matches to PF00072 Response_reg, score 90.9, E-value 2.2E-027, and to PF00486 Trans_reg_C, score 63.9, E-value 4.8E-016 YP_001490986.1 Pfam matches to PF00089 Trypsin, score 89.1, E-value 8.1E-028, and to PF00595 PDZ, score 33.4, E-value 9.7E-009 YP_001490987.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001490988.1 Pfam match to PF00589 Phage_integrase, score 4, E-value 5.9E-005 YP_001490998.1 Pfam match to PF00005 ABC_tran, score 191.9, E-value 1.4E-054 YP_001490999.1 Pfam match to PF02687 FtsX, score 41.3, E-value 3E-009 YP_001491000.1 Pfam match to PF01258 zf-dskA_traR, score 35.7, E-value 1.5E-007 YP_001491001.1 Pfam match to PF01142 TruD, score 241.5, E-value 1.6E-069 YP_001491004.1 Pfam matches to PF03572 Peptidase_S41, score 262.6, E-value 7.1E-076, and to PF00595 PDZ, score 55.2, E-value 7.3E-015 YP_001491005.1 Pfam match to PF01259 SAICAR_synt, score 73.6, E-value 5.8E-019 YP_001491006.1 Pfam match to PF02700 PurS, score 111.1, E-value 2.9E-030 YP_001491007.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001491009.1 Pfam match to PF01553 Acyltransferase, score 68.1, E-value 1.1E-018 YP_001491010.1 Pfam match to PF02537 CRCB, score 93.5, E-value 5.7E-025 YP_001491011.1 Pfam match to PF02416 MttA_Hcf106, score 71.9, E-value 1.8E-018 YP_001491012.1 Pfam match to PF02416 MttA_Hcf106, score 75.7, E-value 1.3E-019 YP_001491013.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001491014.1 Pfam match to PF02410 DUF143, score 114, E-value 4E-031 YP_001491015.1 Pfam match to PF01467 CTP_transf_2, score 125.1, E-value 1.7E-035 YP_001491016.1 Pfam matches to PF02800 Gp_dh_C, score 305.1, E-value 1.2E-088, and to PF00044 Gp_dh_N, score 256.8, E-value 4.2E-074 YP_001491017.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001491018.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001491019.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001491020.1 Pfam matches to PF02784 Orn_Arg_deC_N, score 256.6, E-value 6.1E-076, and to PF00278 Orn_DAP_Arg_deC, score 121.9, E-value 4.6E-034 YP_001491021.1 Pfam matches to PF00800 PDT, score 149.3, E-value 9.1E-042, and to PF01817 CM_2, score 87.3, E-value 4.2E-023, and to PF01842 ACT, score 27.3, E-value 6.3E-007 YP_001491022.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001491023.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001491024.1 Pfam match to PF03150 CCP_MauG, score 300.9, E-value 2.2E-087 YP_001491025.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001491026.1 Pfam matches to PF02558 ApbA, score 85, E-value 2E-022, and to PF08546 ApbA_C, score 76.6, E-value 7.1E-020 YP_001491028.1 Pfam match to PF00877 NLPC_P60, score 136.5, E-value 6.8E-038 YP_001491029.1 Pfam match to PF00027 cNMP_binding, score 57.8, E-value 3.3E-014 YP_001491031.1 Pfam match to PF03167 UDG, score 215.5, E-value 1.1E-061 YP_001491032.1 Pfam match to PF00171 Aldedh, score 471.2, E-value 1.2E-138 YP_001491033.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis YP_001491034.1 Pfam match to PF04011 LemA, score 304.7, E-value 1.5E-088 YP_001491035.1 Pfam match to PF04536 DUF477, score 25.1, E-value 2.8E-005 YP_001491036.1 Pfam match to PF04536 DUF477, score 151.3, E-value 2.4E-042 YP_001491037.1 Pfam match to PF00702 Hydrolase, score 95.4, E-value 7.1E-027 YP_001491038.1 Pfam match to PF00210 Ferritin, score 78.5, E-value 3.1E-021 YP_001491041.1 Pfam match to PF07690 MFS_1, score 132, E-value 9.7E-037 YP_001491043.1 Pfam matches to PF00990 GGDEF, score 210.7, E-value 3E-060, and to PF00672 HAMP, score 26.7, E-value 7.5E-005 YP_001491044.1 Pfam match to PF00529 HlyD, score 162.7, E-value 8.6E-046 YP_001491046.1 Pfam match to PF02321 OEP, score 146.9, E-value 4.8E-041 YP_001491047.1 Pfam matches to PF00593 TonB_dep_Rec, score 67, E-value 5.4E-017, and to PF07660 STN, score 38.4, E-value 2.3E-008, and to PF07715 Plug, score 37.1, E-value 5.6E-008 YP_001491048.1 Pfam match to PF04773 FecR, score 92.8, E-value 9.4E-025 YP_001491049.1 Pfam matches to PF08281 Sigma70_r4_2, score 62.6, E-value 1.7E-017, and to PF04542 Sigma70_r2, score 40.8, E-value 4.4E-009 YP_001491051.1 Pfam match to PF03486 HI0933_like, score 351.2, E-value 1.5E-102 YP_001491053.1 Pfam match to PF01053 Cys_Met_Meta_PP, score 560.2, E-value 2E-165 YP_001491054.1 Pfam match to PF02082 Rrf2, score 123.9, E-value 2.1E-037 YP_001491055.1 Pfam match to PF00291 PALP, score 420.1, E-value 2.8E-123 YP_001491057.1 Pfam match to PF01507 PAPS_reduct, score 210.2, E-value 4.5E-060 YP_001491058.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001491059.1 Pfam matches to PF00009 GTP_EFTU, score 249.9, E-value 4.9E-072, and to PF03144 GTP_EFTU_D2, score 35.6, E-value 1.6E-007 YP_001491060.1 Pfam match to PF01077 NIR_SIR, score 49.1, E-value 1.4E-011 YP_001491062.1 Pfam match to PF00266 Aminotran_5, score 96.1, E-value 9.6E-026 YP_001491063.1 Pfam match to PF00092 VWA, score 47.8, E-value 1.1E-014 YP_001491065.1 Pfam match to PF02654 CobS, score -10.6, E-value 2.3E-008 YP_001491067.1 Pfam match to PF00657 Lipase_GDSL, score 66.8, E-value 6.4E-017 YP_001491068.1 Pfam match to PF02277 DBI_PRT, score -33, E-value 1.1E-008 YP_001491069.1 Pfam match to PF00939 Na_sulph_symp, score 612.5, E-value 3.4E-181 YP_001491070.1 Pfam match to PF01925 DUF81, score 23.6, E-value 7.6E-007 YP_001491071.1 Pfam matches to PF02683 DsbD, score 40.6, E-value 4.8E-009, and to PF00085 Thioredoxin, score 18.8, E-value 4.4E-006 YP_001491072.1 Pfam match to PF08443 RimK, score 283.6, E-value 3.5E-082 YP_001491073.1 Pfam match to PF05618 DUF785, score 56.6, E-value 7.3E-014 YP_001491075.1 Pfam matches to PF00563 EAL, score 199, E-value 1E-056, and to PF00990 GGDEF, score 13.2, E-value 4.6E-008 YP_001491076.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001491078.1 Pfam matches to PF03562 MltA, score 243.2, E-value 4.9E-070, and to PF06725 3D, score 102.7, E-value 1E-027 YP_001491079.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001491080.1 Pfam match to PF01025 GrpE, score 212, E-value 1.2E-060 YP_001491083.1 Pfam match to PF01416 PseudoU_synth_1, score 77.3, E-value 4.3E-020 YP_001491084.1 Pfam match to PF03739 YjgP_YjgQ, score 135.4, E-value 1.5E-037 YP_001491085.1 Pfam match to PF01478 Peptidase_A24, score 46.9, E-value 6.3E-011 YP_001491086.1 catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate YP_001491087.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001491088.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001491089.1 Pfam match to PF00023 Ank, score 27.5, E-value 1.1E-006 YP_001491090.1 Pfam match to PF00271 Helicase_C, score 62.5, E-value 1.7E-020 YP_001491091.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001491092.1 Pfam match to PF00293 NUDIX, score 53.6, E-value 5.9E-013 YP_001491093.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001491094.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001491095.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001491096.1 functions in MreBCD complex in some organisms YP_001491097.1 binds and unfolds substrates as part of the ClpXP protease YP_001491098.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001491099.1 Pfam match to PF07977 FabA, score 192.8, E-value 7.6E-055 YP_001491100.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001491101.1 Pfam match to PF02677 DUF208, score 307.8, E-value 1.8E-089 YP_001491103.1 Pfam match to PF07992 Pyr_redox_2, score 76.7, E-value 6.5E-020 YP_001491104.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001491105.1 Pfam match to PF02321 OEP, score 144.3, E-value 3E-040 YP_001491107.1 Pfam match to PF00529 HlyD, score 123, E-value 7.8E-034 YP_001491108.1 Pfam match to PF00440 TetR_N, score 26, E-value 9.2E-007 YP_001491109.1 Pfam match to PF07690 MFS_1, score 156.6, E-value 5.9E-044 YP_001491110.1 Pfam matches to PF00916 Sulfate_transp, score 245.1, E-value 1.4E-070, and to PF01740 STAS, score 64.3, E-value 3E-018 YP_001491114.1 Pfam match to PF00004 AAA, score 121.7, E-value 1.3E-036 YP_001491116.1 Pfam match to PF02642 DUF191, score 413.9, E-value 2.1E-121 YP_001491117.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001491118.1 Pfam matches to PF01131 Topoisom_bac, score 546.6, E-value 2.4E-161, and to PF01751 Toprim, score 126.9, E-value 5E-035 YP_001491119.1 Pfam match to PF00149 Metallophos, score 45.3, E-value 1.9E-010 YP_001491120.1 catalyzes the formation of biotin from dethiobiotin and sulfur YP_001491123.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001491124.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001491126.1 Pfam match to PF02719 Polysacc_synt_2, score 540, E-value 2.3E-159 YP_001491127.1 Pfam match to PF01041 DegT_DnrJ_EryC1, score 371.6, E-value 1.1E-108 YP_001491128.1 Pfam match to PF02348 CTP_transf_3, score 138.9, E-value 2.6E-039 YP_001491129.1 Pfam matches to PF03102 NeuB, score 419.9, E-value 3.3E-123, and to PF01354 Antifreeze, score 52.3, E-value 1.4E-012 YP_001491133.1 Pfam match to PF02222 ATP-grasp, score 26.3, E-value 5.8E-008 YP_001491134.1 Pfam match to PF04991 LicD, score 23.1, E-value 3.7E-007 YP_001491136.1 Pfam match to PF01973 DUF115, score 50.6, E-value 4.7E-012 YP_001491137.1 Pfam matches to PF00669 Flagellin_N, score 135.7, E-value 1.2E-037, and to PF00700 Flagellin_C, score 95.3, E-value 1.7E-025 YP_001491138.1 Pfam matches to PF00669 Flagellin_N, score 135.5, E-value 1.4E-037, and to PF00700 Flagellin_C, score 85.6, E-value 1.4E-022 YP_001491140.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001491141.1 Pfam matches to PF01368 DHH, score 166.2, E-value 1.4E-048, and to PF02272 DHHA1, score 74.8, E-value 2.6E-019 YP_001491144.1 Pfam match to PF01965 DJ-1_PfpI, score 124, E-value 3.8E-034 YP_001491145.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001491146.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001491149.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001491150.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001491151.1 Pfam match to PF01027 UPF0005, score 135.4, E-value 1.5E-037 YP_001491153.1 Pfam match to PF08242 Methyltransf_12, score 29.1, E-value 1.4E-005 YP_001491154.1 Pfam match to PF03840 SecG, score 93.5, E-value 5.9E-025 YP_001491155.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001491156.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001491157.1 Pfam match to PF06271 RDD, score 72.7, E-value 1.1E-018 YP_001491159.1 Pfam match to PF01544 CorA, score -12.3, E-value 1.1E-005 YP_001491160.1 Pfam match to PF03883 DUF328, score 173.5, E-value 5E-049 YP_001491161.1 Pfam match to PF00633 HHH, score 36.2, E-value 7.2E-010 YP_001491163.1 Pfam match to PF00149 Metallophos, score 73.5, E-value 6.1E-019 YP_001491165.1 Pfam matches to PF00593 TonB_dep_Rec, score 74.4, E-value 3.2E-019, and to PF07715 Plug, score 62.8, E-value 1E-015 YP_001491166.1 Pfam match to PF00165 HTH_AraC, score 35.3, E-value 2E-007 YP_001491167.1 Pfam match to PF00011 HSP20, score 105.8, E-value 1.2E-028 YP_001491169.1 Pfam match to PF00015 MCPsignal, score 158.4, E-value 1.7E-044 YP_001491170.1 Pfam matches to PF00899 ThiF, score 243.6, E-value 3.7E-070, and to PF05237 MoeZ_MoeB, score 182.4, E-value 1E-051, and to PF00581 Rhodanese, score 70.9, E-value 3.8E-018 YP_001491171.1 Pfam matches to PF08379 Bact_transglu_N, score 120.2, E-value 5.5E-033, and to PF01841 Transglut_core, score 82.6, E-value 1.1E-021 YP_001491172.1 Pfam matches to PF04169 DUF404, score 358.8, E-value 8E-105, and to PF04174 DUF407, score 146.9, E-value 5E-041, and to PF04168 DUF403, score -73.3, E-value 6.3E-008 YP_001491173.1 Pfam matches to PF01841 Transglut_core, score 67.6, E-value 3.8E-017, and to PF08379 Bact_transglu_N, score 67.4, E-value 4.2E-017 YP_001491174.1 Pfam match to PF00005 ABC_tran, score 245.5, E-value 1.1E-070 YP_001491175.1 Pfam match to PF00528 BPD_transp_1, score 68.2, E-value 2.3E-017 YP_001491176.1 Pfam match to PF00528 BPD_transp_1, score 129.8, E-value 6.8E-036 YP_001491177.1 Pfam match to PF00291 PALP, score 420.1, E-value 2.8E-123 YP_001491178.1 Pfam match to PF00563 EAL, score 195.9, E-value 8.7E-056 YP_001491180.1 Pfam match to PF01547 SBP_bac_1, score 32.1, E-value 1.8E-006 YP_001491181.1 Pfam match to PF02082 Rrf2, score 144.8, E-value 9E-044 YP_001491183.1 Pfam match to PF04952 AstE_AspA, score 55.4, E-value 1.7E-013 YP_001491185.1 Pfam matches to PF04169 DUF404, score 263, E-value 5.4E-076, and to PF04174 DUF407, score 149.8, E-value 6.6E-042 YP_001491186.1 Pfam matches to PF00009 GTP_EFTU, score 240.6, E-value 3E-069, and to PF00679 EFG_C, score 89.3, E-value 1.1E-023, and to PF03144 GTP_EFTU_D2, score 52.6, E-value 1.2E-012 YP_001491187.1 Pfam match to PF04143 DUF395, score 80.3, E-value 5.4E-021 YP_001491188.1 Pfam match to PF01206 SirA, score 131, E-value 3E-036 YP_001491192.1 Pfam matches to PF00593 TonB_dep_Rec, score 83.9, E-value 4.7E-022, and to PF07715 Plug, score 74.4, E-value 3.4E-019, and to PF07660 STN, score 21, E-value 1.4E-005 YP_001491193.1 Pfam match to PF04773 FecR, score 73.9, E-value 4.6E-019 YP_001491194.1 Pfam matches to PF08281 Sigma70_r4_2, score 59.8, E-value 1.1E-016, and to PF04542 Sigma70_r2, score 26.7, E-value 7.4E-005 YP_001491195.1 Pfam matches to PF00990 GGDEF, score 164.3, E-value 4.5E-047, and to PF08447 PAS_3, score 101.3, E-value 2.7E-027 YP_001491196.1 Pfam matches to PF00884 Sulfatase, score 205.8, E-value 9.1E-059, and to PF08019 DUF1705, score 201.9, E-value 1.4E-057 YP_001491200.1 Pfam match to PF01292 Ni_hydr_CYTB, score 70.3, E-value 5.6E-018 YP_001491203.1 Pfam matches to PF00072 Response_reg, score 116.3, E-value 3.5E-035, and to PF00486 Trans_reg_C, score 47.5, E-value 4E-011 YP_001491204.1 Pfam matches to PF00672 HAMP, score 56.7, E-value 7.1E-014, and to PF02518 HATPase_c, score 28.9, E-value 1.6E-005 YP_001491205.1 Pfam match to PF08241 Methyltransf_11, score 124.7, E-value 2.4E-034 YP_001491206.1 Pfam match to PF00165 HTH_AraC, score 46.5, E-value 7.9E-011 YP_001491207.1 Pfam match to PF01966 HD, score 109.4, E-value 9.7E-030 YP_001491208.1 Pfam match to PF02511 Thy1, score -37.9, E-value 4.9E-006 YP_001491209.1 Pfam match to PF04960 Glutaminase, score 515.8, E-value 8E-165 YP_001491210.1 Pfam match to PF03458 UPF0126, score 95, E-value 2.1E-025 YP_001491212.1 Pfam match to PF00551 Formyl_trans_N, score 120.3, E-value 4.9E-033 YP_001491213.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity