-- dump date   	20140618_205857
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_931506.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_931507.1	DNA polymerase III beta chain (EC 2.7.7.7). DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA It slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity). InterPro: DNA polymerase III beta chain dnan: DNA polymerase III beta subunit; High confidence in function and specificity
YP_931508.1	negatively supercoils closed circular double-stranded DNA
YP_931509.1	METHYLATION OF SPECIFIC ADENINE RESIDUES; REQUIRED FOR BOTH RESTRICTION AND MODIFICATION ACTIVITIES (BY SIMILARITY), TREMBL:Q7VCN2 (55% identity). InterPro (IPR002296): N6 adenine-specific DNA methyltransferase,N12 class. InterPro (IPR003356): N-6 DNA methylase. InterPro (IPR003665): Type I restriction-modification system M subunit. Pfam (PF02384): N-6 DNA Methylase. Pfam (PF02506): Type I restriction modification system, M protein.; High confidence in function and specificity
YP_931510.1	Putative restriction modification gene,; Function unclear
YP_931511.1	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank no domains predicted no signal peptide no TMHS
YP_931512.1	S subunit, DNA SPECIFICITY SUBUNIT REQUIRED FOR RESTRICTION AND MODIFICATION, TREMBL:Q9AAH7 (31% identity); TREMBL:Q8PIJ8 (28% identity). Pfam (PF01420): Type I restriction modification DNA specificity domain. InterPro (IPR000055): Restriction modification system DNA specificity domain.; High confidence in function and specificity
YP_931513.1	Conserved hypothetical protein. Homology to RB11641 of R.baltica of 42% (tremble:Q7TTG8). No domains predicted. No TMHs. No signal peptide.
YP_931514.1	Transcriptional regulatory protein, 35% identity to TrEMBL;Q89JK0. Has Prosite, PS01117; HTH_MARR_1 domain; The marR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH)domain of about 135 amino acids present in transcription regulators of the marR/slyA family,involved in the development of antibiotic resistance; Function unclear
YP_931515.1	SUBUNIT R IS REQUIRED FOR BOTH NUCLEASE AND ATPASE ACTIVITIES BUT NOT FOR MODIFICATION (BY SIMILARITY),TREMBL:Q9AAH5 (64% identity); TREMBL:Q8FUH0 (40% identity). InterPro (IPR001410): DEAD/DEAH box helicase TIGRFAM (TIGR00348): Type I site-specific deoxyribonuclease, HsdR family.; High confidence in function and specificity
YP_931516.1	The short-chain dehydrogenases/reductases family is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases, similarity to SWISSPROT:P37959 (35% identity); TREMBL:Q930L8 (44% identity); TREMBL:Q9I3W5 (41% identity). Pfam (PF00106): Short chain dehydrogenase. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase.; Specificity unclear
YP_931517.1	Transcriptional regulator, LysR family,; High confidence in function and specificity
YP_931518.1	Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs .; Family membership
YP_931519.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_931520.1	Conserved hypothetical protein, 50% identitcal(67% similarity) to TrEMBL;Q888U7.TrEMBL;Q747X0(33% identity). Has PF03473, MOSC domain;IPR005302; The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes. These MOSC domains contain an absolutely conserved cysteine and occur either as stand-alone forms such as P32157, or fused to other domains such as NifS-like catalytic domain in Molybdenum cofactor sulfurase. The MOSC domain is predicted to be a sulfur-carrier domain that receives sulfur abstracted by the pyridoxal phosphate-dependent NifS-like enzymes, on its conserved cysteine,and delivers it for the formation of diverse sulfur-metal clusters.; Function unclear
YP_931521.1	Conserved hypothetical membrane protein. Homology to Daro03002995 of Dechloromonas aromatica of 34% (ZP_00348572.1). No signal peptide present. TMHMM reporting one transmembrane helix. No domains predicted.; Conserved hypothetical protein
YP_931522.1	Hypothetical protein, 28% identity to TrEMBL;Q8E8U4. Has PF07049, Protein of unknown function (DUF1332); IPR010755;This family consists of several hypothetical bacterial proteins of around 165 residues in length. The function of this family is unknown.; Function unclear
YP_931523.1	InterPro (IPR002818): ThiJ/PfpI. Pfam (PF01965): DJ-1/PfpI family.; Specificity unclear
YP_931524.1	This family includes extracellular ligand binding domains of a wide range of receptors and it also includes the bacterial amino acid binding proteins of known structure. Similar to trembl|Q8XVG7 (38%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Function unclear
YP_931525.1	Probable transcriptional regulator, LysR family,; Family membership
YP_931526.1	Probable isoquinoline 1-oxidoreductase, alpha subunit Homology to iroA of B. diminuta of 58% (sprot|IORA_BREDI). InterPro: [2Fe-2S] binding domain (IPR002888); Ferredoxin (IPR001041) Pfam: 2FE-2S iron-sulfur cluster binding domein, [2Fe-2S] binding domain no signal peptide no TMHs; Specificity unclear
YP_931527.1	Putative isoquinoline 1-oxidoreductase, beta subunit Homology to iorB of B. diminuta of 34% (sprot|IORB_BREDI). InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus (IPR000674) Pfam: Aldehyde oxidase and xanthine dehydrogenase signal peptide no TMHs; Family membership
YP_931528.1	Conserved hypothetical protein (Xanthine like-dehydrogenase accessory factor). Homology to Rsc1464 (hyp. protein) of R. solanacearum of 66% (CAD15165). InterPro: DUF182 Pfam: uncharacterized BCR, COG1975 no signal peptide no TMHs
YP_931529.1	Purine catabolism protein pucB. TREMBL:Q8XZ0: 40% identity, 47% similarity Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase. FUNCTION: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) (By similarity). PATHWAY: Molybdenum cofactor biosynthesis. SUBCELLULAR LOCATION: Cytoplasmic (By similarity). SIMILARITY: Belongs to the mobA family. Pfam:UPF0007:Uncharacterized protein family UPF000 ispD: 4-diphosphocytidyl-2C-methyl-D-er Non-secretory protein with signal peptide probability: 0 No TMH's (TMHMM predicted).; Function unclear
YP_931530.1	Hypothetical protein yddH. TREMBL:Q7NTI1:66% identity, 76% similarity InterPro:IPR002563; Flavin_Reduct. Pfam:PF01613; Flavin_Reduct; InterPro: Flavin reductase-like domain Non-secretory protein with no signal peptide. No transmembrane helices TIGR00357: PilB-related protein; High confidence in function and specificity
YP_931531.1	dTDP-glucose 4,6-dehydratase, AcbB,probably involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. 30% dTDP_gluc_dehyt.IPR001509; Epimerase_Dh. Pfam:PF01370; Epimerase; 1. TIGRFAMs:TIGR01181; dTDP_gluc_dehyt; 1.; High confidence in function and specificity
YP_931532.1	Putative glycosyl transferase. Weak Homology with hits spanning the entire length of protein. 24% identitcal to TrEMBL;Q8F209.TrEMBL; Q89D69(33% identity) Has PF00535,Glycosyl transferase:IPR001173;Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These are enzymes that catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules,forming glycosidic bonds.; Family membership
YP_931533.1	Conserved hypothetical membrane protein Homology to cv0580 of C. violaceum of 41% (trembl|Q7P0I7(SRS)) no domains predicted no signal peptide 2 TMHs; Conserved hypothetical protein
YP_931534.1	Similar to a tellurium resistance protein TerC. Belongs to the terC family. This family contains a number of integral membrane proteins that also contains the TerC protein. TerC has been implicated in resistance to tellurium. Similar to a putative membrane protein TerC,80% identity to TrEMBL; Q5P410 from Azoarcus sp EnN1. 50% RNA_rec_mot.IPR005496; TerC. Pfam:PF03741; TerC; 1. TIGR:SPTO2691. TMHelix:5.; Conserved hypothetical protein
YP_931535.1	HTH-type transcriptional regulator gltR. POSITIVE REGULATOR OF GLUTAMATE BIOSYNTHESIS (GLTAB GENES). NEGATIVELY REGULATES ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|GLTR_BACSU (33% Bacillus subtilis, HTH-type transcriptional regulator GltR) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_931536.1	Permease member of the Major Facilitator Superfamily (MFS).MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 25% MFS.IPR005828; Sub_transporter. Pfam:PF00083; sugar_tr; 1. TMHelix: 10.; High confidence in function and specificity
YP_931537.1	Conserved hypothetical protein. Homology to nfa21510 of Nocardia farcinica of 31% (trembl:Q5YXU4). No domains predicted. No TMHs. No signal peptide.
YP_931538.1	Conserved hypothetical protein. Homology to nfa21510 of Nocardia farcinica of 42% (trembl:Q5YXU4). No domains predicted. No TMHs. No signal peptide.
YP_931539.1	Conserved hypothetical secreted protein. Homology to PP2042 of P. putida of 34% (TrEMBL;Q88L93) Has PF06980:(IPR010727)Protein of unknown function (DUF1302);This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. No TMHs signal peptide present.; Conserved hypothetical protein
YP_931540.1	Conserved hypothetical secreted protein. Homology to PA3421 of P. aeruginosa of 50% (TrEMBL;Q9HYI4) Has (IPR010752)PF07044:Protein of unknown function (DUF1329);This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs signal peptide present; Conserved hypothetical protein
YP_931541.1	Conserved hypothetical BNR domain protein. Homology to pp3201 of P. putida of 40% (trembl|Q88I01). InterPro: BNR repeat (IPR002860) Pfam: BNR repeat BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide no TMHs; Function unclear
YP_931542.1	Putative membrane protein MJ1562. TREMBL:Q88LB6: 47% identity, 63% similarity InterPro:IPR000731; SSD_5TM InterPro: HMGCR/Patched 5TM box Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide absent. Presence of 12 transmembrane helices; Family membership
YP_931543.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. EntA,a 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase enzyme,is involved in the third stage of enterobactin biosynthesis and converts isochorismate to 2,3-dihydroxybenzoic acid (DHBA), SWISSPROT:Q10855 (37% identity); TREMBL:Q89M15 (36% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. InterPro (IPR003560): 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_931544.1	Conservd hypothetical protein, 79% identity(85% similarity) to TrEMBL;Q88GU7. Has PF02566, OsmC-like protein; IPR003718; Osmotically inducible protein C (OsmC) (P23929) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein (O68390) that has a novel pattern of oxidative stress regulation. Has PF02624, YcaO-like fatty acid binding protein;IPR003776, DUF181;This is a family of proteins of unknown function.
YP_931545.1	Putative AraC-family transcriptional regulator,; Family membership
YP_931546.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q9I376 (49% identity); SWISSPROT:P50197 (44% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_931547.1	Conserved hypothetical secreted protein. Homology to bll2189 of B. japonicum of 48% (trembl|Q89T61). Has PF06577, Protein of unknown function (DUF1134);IPR008325,UCP033924; This family consists of several hypothetical bacterial proteins of unknown function. Signal peptide. TMH present in signal peptide.; Conserved hypothetical protein
YP_931548.1	Hypothetical UPF0271 protein PYRAB09930. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes,lamA and lamB, involved in the utilization of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression [1]. The exact molecular function of the proteins in this family is unknown. SPROT:Q89LH6: 47% identity, 62% similarity InterPro:IPR005501; LamB_YcsF. Pfam:PF03746; LamB_YcsF urease_gam: urease gamma subunit Nonsecretory protein with Signal peptide probability 0 No transmembrane helices; Family membership
YP_931549.1	Conserved hypothetical urea amidolyase-related protein. Homology to ybgK of E. coli of 36% (sprot|YBGK_ECOLI). InterPro: DUF183 (IPR003778) Uncharacterized domain in proteins of unknown function. This domain is found in a multifunctional enzyme, urea amidolyase, from yeast. Pfam: DFU182, uncharcterized ACR,COG1984 no signal peptide no TMHs; Function unclear
YP_931550.1	Conserved hypothetical protein ybgJ. Homology to ybgJ of E. coli of 41% (sprot|YBGJ_ECOLI) InterPro: DUF213 (IPR003833) Pfam: DUF213, uncharacterized ACR, COG2049 no signal peptide no TMHs; Function unclear
YP_931551.1	Hypothetical haloacetate dehalogenase H-1 (EC 3.8.1.3). Haloacetate + H(2)O = glycolate + halide TREMBL:Q8Y2S9: 58% identity, 67% similarity Gene name:dehH from Ralstonia solanacearum genome project. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1 nadp_idh_euk: isocitrate dehydrogenase No TMH present absence of signal peptide.; Family membership
YP_931552.1	Conserved hypothetical secreted protein Homology to pa4487 of P. aeruginosa of 52% (trembl|Q9HVT4(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein
YP_931553.1	Conserved hypothetical secreted protein. Homology to rsc3028 of R. solanacearum of 57% (trembl|Q8XV04(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein
YP_931554.1	Conserved hypothetical secreted protein. Homology to PA4488 of P. aeruginosa of 47% (trembl|Q9HVT3(SRS)) No domains predicted. No TMHs. Singal Peptide Present.; Conserved hypothetical protein
YP_931555.1	This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate,TREMBL:Q9LBN6 (35% identity); TREMBL:Q46334 (34% identity). SignalP predicting signal peptide.; High confidence in function and specificity
YP_931556.1	Conserved hypothetical membrane protein. Homology to ebA624 of Azoarcus sp. EbN1 of 52% (gnl|keqq|eba:ebA624(KEGG)) . no domains predicted. no signal peptide. 3 TMHs
YP_931557.1	Hypothetical secreted protein. No homology of the entire protein to the data bank. InterPro:Esterase/lipase/thioesterase family active site Pfam:Putative serine esterase (DUF676) This family of proteins are probably serine esterase type enzymes. Signal peptide present (Signal P predicted) No transmembrane helices.
YP_931558.1	Probable two component sensor histidine kinase,; Specificity unclear
YP_931559.1	Two component response regulator,; Specificity unclear
YP_931560.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:O54136 (41% identity); TREMBL:Q8RCZ7 (40% identity). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership
YP_931561.1	Conserved hypothetical membrane protein. Homology to cv3942 of C. violaceum of 30% (trembl|Q7NR42) InterPro: DUF214 (IPR003838) Pfam: Predicted permease This is a family of predicted permeases and hypothetical transmembrane proteins. One member has been shown to transport lipids targeted to the outer membrane across the inner membrane, a step which requires ATP. Signal peptide 3 TMHs; Conserved hypothetical protein
YP_931562.1	Conserved hypothetical secreted protein. Homology to BPSS2323 of Burkholderia pseudomallei of 45% (trembl:Q63HU7). no domains predicted. singal peptide. no TMHs; Conserved hypothetical protein
YP_931563.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide TMHs inside of the signal peptide.
YP_931564.1	Conserved hypothetical secreted protein. Homology to rsc3030 of R. solanacearum of 48% (sprot|YU30_RALSO) Pfam: Alpha-2-macroglobulin family Nterminal region (PF01835, PF07703) signal peptide no TMHs; Conserved hypothetical protein
YP_931565.1	Conserved hypothetical secreted protein. Homology to RS04726 of R. solanacearum of 55% (trembl|Q8XV01(SRS)) Has PF06672;(IPR009558)Protein of unknown function (DUF1175):This family consists of several hypothetical bacterial proteins of around 210 residues in length. The function of this family is unknown. No TMHs signal peptide present.; Conserved hypothetical protein
YP_931566.1	Conserved hypothetical secreted protein. Homology to RS04725 of Ralstonia solanacearum of 43% (trembl|Q8XV00(SRS)) No domains predicted. Signal Peptide Present. NO TMH reported present.; Conserved hypothetical protein
YP_931567.1	Conserved hypothetical protein. Homology to MCA0287 of Methylococcus capsulatus of 48% (trembl:Q60C24). no domains predicted. no signal peptide. no TMHs
YP_931568.1	Hypothetical protein. No good homology to the data bank. No domains predicted. No TMHs Probable signal peptide.
YP_931569.1	Hypothetical protein ydiK.Integral membrane protein (potential). similarity:belongs to the upf0118 (perm) family TREMBL:Q7WQ94: 68% identity; 81% similarity. PIR:AD2790; AD2790.C97569; C97569. InterPro:IPR000585; Hemopexin. IPR002549; UPF0118. Pfam: PF01594; UPF0118; 2A0604s01: protein-export membrane pro Pfam: presence of DUF20 domain and branched chain amino acid transport. TIGRFAM: general nitrate transport. Signal P predicted signal peptide and TMHMM predicted transmembrane helices.; Function unclear
YP_931570.1	64% similarity with ABC-type multidrug transport system, ATPase and permease components [Dechloromonas aromatica RCB]. and
YP_931571.1	Enoyl-CoA hydratase and 3-2trans-enoyl-CoA isomerase are two enzymes involved in fatty acid metabolism. ECH catalyzes the hydratation of 2-trans-enoyl-CoA into 3-hydroxyacyl-CoA and ECI shifts the 3- double bond of the intermediates of unsaturated fatty acid oxidation to the 2-trans position.In Escherichia coli (gene fadB) and Pseudomonas fragi (gene faoA), ECH and ECI are also part of a multifunctional enzyme which contains both a HCDH and a 3-hydroxybutyryl-CoA epimerase domain. InterPro: Enoyl-CoA hydratase/isomerase Entry name TREMBL:Q8PMW0 Prim. accession # Q8PMW0 InterPro IPR001753; EnCoA_hydrtse. Pfam PF00378; ECH; 1 Identities = 169/379 (44%) Number of predicted TMHs: 0 Signal peptide probability: 0.000; Family membership
YP_931572.1	DNA polymerase III polC-type (EC 2.7.7.7) (PolIII). Required for replicative DNA synthesis. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). InterPro: Exonuclease dnaq: DNA polymerase III epsilon subun; High confidence in function and specificity
YP_931573.1	Hypothetical protein. No good homology with any hits of this length protein. No Domains/Features/motifs/signal peptide present.
YP_931574.1	Conserved hypothetical globin-like protein. Homology to rpa2719 of R. palustris of 46% (tremblnew|CAE28161). Interpro: IPR009050 Globin-like. Globins are heme-containing proteins involved in binding and/or transporting oxygen. This family of heme binding proteins are found mainly in bacteria. No signal peptide. No TMHs; Function unclear
YP_931575.1	Hypothetical membrane protein. no homology to the data bank. no domains predicted.signal peptide. 1 TMHs
YP_931576.1	Sigma-54 dependent response regulator,; Specificity unclear
YP_931577.1	Putative two component sensor histidine kinase,; Specificity unclear
YP_931578.1	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Probable sugar-proton symporter transmembrane protein ProP proline/betaine transporter. Low homology to the hypothetical protein ycxA (ORF5)involved in the biosynthesis of the pepitde antibiotic Bacitracin in B. subtilis. Signal peptide; Specificity unclear
YP_931579.1	Hypothetical protein yfbK. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders [1]. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. trembl:Q8P6Q2: 55% identity; 66% similarity InterPro:IPR002016; Peroxidase. IPR002035; VWF_A. Pfam: PF00092; VWA; 1. SMART: SM00327; VWA; 1. cdhD: CO dehydrogenase/acetyl-CoA syn Signal peptide present (0.927 probability); SignalP predicted. No transmembrane helices (TMHMM predicted).; Function unclear
YP_931580.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_931581.1	Conserved hypothetical membrane protein. Homology to BB3269 of Bordetella bronchiseptica of 31% (trembl|Q7WHD9(SRS)). No domains predicted. no signal peptide 1 TMH; Conserved hypothetical protein
YP_931582.1	Hypothetical protein. No Good homologs. No Domains/Features/Motifs reported present.
YP_931583.1	Hypothetical protein. Weak homology with hits over entire length. PS50821; PAZ domain present(Prosite)
YP_931584.1	rtcB protein, 57% identical(70% similairty) to TrEMBL;Q7NZ85 TrEMBL;Q8FCS7(56% identity). Has IPR001233;UPF0027(PF01139, Uncharacterized protein family):A number of uncharacterized proteins including Escherichia coli rtcB, Mycobacterium tuberculosis MtCY441.01., Caenorhabditis elegans F16A11.2 and Methanococcus jannaschii MJ0682 belong to this family. Has no Signal peptide or TMH present.; High confidence in function and specificity
YP_931585.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
YP_931586.1	Conserved hypothetical membrane protein. Homology to pa4965 ao P. aeruginosa of 50% (trembl|Q9HUK0) Pfam: Retroviral aspartyl protease no signal peptide 1 TMHs; Conserved hypothetical protein
YP_931587.1	Required for efficient pilin antigenic variation
YP_931589.1	Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) (16S pseudouridylate 516 synthase) (16S pseudouridine 516 synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.; Family membership
YP_931590.1	Conserved hypothetical protein. Homology to RS04117 of R.solanacearum of 52% (tremble:Q8Y0H4) No domains predicted. No signal peptide. No TMHs
YP_931591.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_931592.1	Hypothetical secreted protein. Homology to RS00193 of R. solanacearum of 26% (tremble:Q8XVC9) PF02987, Late embryogenesis abundant protein;IPR004238;Different types of LEA proteins are expressed at different stages of late embryogenesis in higher plant seed embryos and under conditions of dehydration stress. The function of these proteins is unknown. No TMHs Signal peptide present
YP_931593.1	UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A). The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB the uvrA molecules dissociate (By similarity). InterPro: Excinuclease ABC A subunit; High confidence in function and specificity
YP_931594.1	Conserved hypothetical hydrogenase cytochrome b-type subunit. Homology to C. vinosum of 56% (trembl|Q46471). Involved in electron transfer from hydrogen to oxygen. probable signal peptide probable 4 TMHs; Family membership
YP_931595.1	Probable cytochrome c'. Homology to cycA of C. vinosum of 61% (sprot|CYCP_CHRVI). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN. Pfam: Cytochrome c. signal peptide no TMHs; Function unclear
YP_931596.1	Methyl-accepting chemotaxis protein,; Specificity unclear
YP_931597.1	Probable serine protease. Homology to mucD of P. aeruginosa of 55% (AAC43718). Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs; High confidence in function and specificity
YP_931598.1	23% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1.; High confidence in function and specificity
YP_931599.1	oxyR, Hydrogen peroxide-inducible genes activator. BELONGS TO THE LYSR FAMILY OF TRANSCRIPTIONAL REGULATORS REQUIRED FOR THE INDUCTION OF A REGULON OF HYDROGEN PEROXIDE INDUCIBLE GENES SUCH AS CATALASE GLUTATHIONE-REDUCTASE ETC. (BY SIMILARITY). mreB: cell shape determining protein M 51% HTH_LysR. IPR005119; LysR_subst. IPR009058; Wing_hlx_DNA_bnd. PF00126; HTH_1; 1. PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity
YP_931600.1	decatenates replicating daughter chromosomes
YP_931601.1	Protein smg homolog, 45% identity (65% similarity) to SwissProt;P30853 43% identity to SwissProt;Q8X8F6,E.coli smg protein. Has PF04361(IPR007456):Protein of unknown function (DUF494);Members of this family of uncharacterised proteins are often named Smg. No signal peptide or TMH reported present.
YP_931602.1	Putative DNA processing protein DrpA (Smf protein). Homology to drpA of H. influcenzae The SMF family (DNA processing chain A, dprA) are a group of bacterial proteins. In Helicobacter pylori, dprA is required for natural chromosomal and plasmid transformation InterPro: SMF family Tigerfam: dprA: DNA processing protein DprA,putative Pfam SMF family no signal peptide no TMHs; Family membership
YP_931603.1	Conseved hypothetical membrane protein. Homology to RSO2271 of R. solanacearum of 36% (trembl|Q8Y3B1(SRS)). Pfam: Lysin motif (SM00257) This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. No signal peptide 1 TMH; Conserved hypothetical protein
YP_931604.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_931605.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_931606.1	Putative protease HtpX Homolog to htpX of E. coli of 30% (AAA62779) InterPro: Peptidase family M48 (IPR001915) Pfam: Peptidase family M48 signal peptide TMHs3; Family membership
YP_931607.1	Putative thiol:disulfide oxidoreductase. Homology to helX of R. casulata of 35% Periplasmic protein thiol:disulphide oxidoreductase is involved in the biogenesis of c-type cytochromes as well as in disulphide bond formation in some periplasmic proteins. Tigrfam: dsbE: periplasmic protein thiol:disulfide signal peptide no TMHs; High confidence in function and specificity
YP_931608.1	Conserved hypothetical secreted protein. Homology to SMa0025 of S. meliloti of 46% pir|D95263(SRS). Pfam: Transglutaminase_like Superfamily signal peptide no TMHs; Conserved hypothetical protein
YP_931609.1	Conserved hypothetical secreted protein. Homology to ebA582 of Azoacrus sp EbN1 (trembl:Q5P8D6). No domains predicted. SignalP reporting signal peptid. no TMHs; Conserved hypothetical protein
YP_931610.1	Probable thiol peroxidase. Homology to E. coli of 62% (sprot:TPX_ECOLI) Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity). Pfam: AhpC/TSA family no signal peptide no TMHs; High confidence in function and specificity
YP_931611.1	Conserved hypothetical membrane protein. Homology to an orf of R. palustris (tremblnew|CAE28417). Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter InterPro: Integral membrane protein DUF6 Pfam: Integral membrane protein DUF6 no signal peptide probable 10 TMHs; Conserved hypothetical protein
YP_931612.1	conserved hypothetical membrane proteins, 42% identity (59% similarity) to TrEMBL;Q73PF0 Has PF02592;Uncharacterized ACR, YhhQ family COG1738;IPR003744:This is a family of uncharacterized proteins. Conserved regions of hydrophobicity suggest that all members of the family may be integral membrane proteins. no signal peptide. 4 TMH.; Conserved hypothetical protein
YP_931613.1	Conserved hypothetical secreted protein. Homology to XCC0740 of Xanthomonas campestris of 33% (trembl|Q8PCI6(SRS) Pfam: Glycosyl hydrolases family 2,TIM barrel domain This family contains beta-galactosidase,beta-mannosidase and beta-glucuronidase activities. No TMHs Signal peptide: present.; Conserved hypothetical protein
YP_931614.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
YP_931615.1	Pirin-like protein. TREMBL:Q8P799: 52% identity,65% similarity. InterPro: DUF209 his region is found the C-terminal half of the Pirin protein. The function of Pirin is unknown but the gene coding for this protein is known to be expressed in all tissues in the human body although it is expressed most strongly in the liver and heart. Pirin is known to be a nuclear protein, exclusively localised within the nucleoplasma and predominantly concentrated within dot-like subnuclear structures. A tomato homologue of human Pirin has been found to be induced during programmed cell death. Human Pirin interacts with Bcl-3 and NFI and hence is probably involved in the regulation of DNA transcription and replication. It appears to be an Fe(II)-containing member of the Cupin superfamil InterPro:IPR007113; Cupin_sup. IPR008778; Pirin_C. IPR003829; Pirin_N. Pfam PF02678; Pirin; 1. PF05726; Pirin_C molyb_syn: molybdenum cofactor synthesis Absence of transmembrane helices (TMHMM predicted); Function unclear
YP_931616.1	Putative Alcohol dehydrogenase. Homology to adh-HT of B. stearothermophilus (sprot|ADH3_BACST) THERMOSTABLE AND THERMOPHILIC NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. BEARS MAINLY AN ETHANOL-DEHYDROGENASE ACTIVITY. CATALYTIC ACTIVITY:An alcohol + NAD(+) = an aldehyde or ketone + NADH. COFACTOR: Binds 2 zinc ions per subunit (By similarity). Pfam: Zinc-binding dehydrogenase Tirgfam: tdh: L-threonine 3-dehydrogenase no signal peptide no TMHs; Family membership
YP_931617.1	Putative transcriptional regulator. Homology to gstR of R. leguminosarum of 37% (tremble:Q52827). Has PF00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family.IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC,iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR,nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini. Has PF03466, LysR substrate binding domain;IPR005119, LysR_subst; The structure of this domain is known and is; High confidence in function and specificity
YP_931618.1	Probabe glutathione transferase. Homology to gstA of R. leguminosarum of 58% (sprot:GSTA_RHILE) Conjugation of reduced glutathione to a variety of targets. Pfam: PF02798, GST_N, Glutathione S-transferase, N-terminal domain; PF00043, GST_C, Glutathione S-transferase, C-terminal domain Interpro: IPR004045, GST_Nterm; IPR004046,GST_Cterm; no signal peptide no TMHs; High confidence in function and specificity
YP_931619.1	Conserved hypothetical protein. Homology to bp2124 of B. pertussis of 48% (trembl|Q7VWS5). Pfam: Pyridoxamine 5-phosphate oxidase no signal peptide no TMHs
YP_931620.1	MaoC protein (Phenylacetic acid degradation protein paaZ). Entry name :- TREMBL:Q8XXS0 Prim. accession # Q8XXS0 InterPro:-IPR002539; MaoC_dehydratas. Pfam:-PF01575; MaoC_dehydratas; 1. Identities = 77/145 (53%) Number of predicted TMHs: 0
YP_931621.1	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile
YP_931622.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XU49 (72%) and to sprot|BRAF_PSEAE (40%). Pfam: ABC transporter Smart: AAA ATPases; Specificity unclear
YP_931623.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7W5F6 (63%) and to trembl|Q8U8G7 (59%). Pfam (PF00005): ABC transporter Smart (SM00382): ATPase superfamily; Specificity unclear
YP_931624.1	ABC transporter substrate binding proteins count to the family of extracellular ligand binding proteins. It is a component of the high affinity amino acid transport system. Similar to trembl|Q8XU51 (58%) and to tremblnew|CAE27314 (45%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_931625.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q92LQ5 (71%) and to trembl|Q8XU52 (69%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting eight Tmhelix.; Specificity unclear
YP_931626.1	Putative branched-chain amino acid transport permease. Homology to livM of S. typhimurium of 25%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: branch-chain amino acid transport system probable signal peptide probable 6 TMHs; Specificity unclear
YP_931627.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_931629.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted signal peptide no TMHs
YP_931630.1	Conserved hypothetical secreted protein,; Conserved hypothetical protein
YP_931631.1	Conserved hypothetical protein with 74% similarity(57% identity)to Conserved hypothetical protein [Sinorhizobium meliloti]. No Signal peptide reported to be present. No TMH reported to be present. Has PF07045,Protein of unknown function (DUF1330)This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown. TIGRFAM:acolac_sm: acetolactate synthase,small s; Family membership
YP_931632.1	Hypothetical protein, 40% identity to TrEMBL;Q73S36 Weak Homology with most protein hits in the database. No Domains/Features/Motifs predicted present.
YP_931633.1	Conserved hypothetical membrane protein, 50% identity (62% similarity) to TrEMBL;Q7NQ67. No domains predicted TMHMM2 reporting 1 TMH's present. No signal peptide reported present.; Conserved hypothetical protein
YP_931634.1	The Tap (taxis toward peptides) receptor and the periplasmic dipeptide-binding protein (DBP) of Escherichia coli together mediate chemotactic responses to dipeptides. Similar trembl|Q7P0E0 (32%) and to SWISSPROT:MCPC_SALTY (23%). Pfam(PF00015): Bacterial chemotaxis sensory transducer Pfam (PF00672):HAMP domain TMHMM reporting two TMH. SignalP reporting Signalpeptid.; Specificity unclear
YP_931635.1	The ability of bacteria to recognize and swim toward aromatic hydrocarbons is possibly an important prelude to their degradation. In Pseudomonas putida G7,NahY is the receptor required for the chemotaxis to naphthalene. Similar to trembl|Q7NU44 (38%) and to trembl|Q7NY58 (33%). Smart: HAMP domain Pfam (PF00015): Methyl-accepting chemotaxis protein (MCP) signalling domain SignalP reporting Signal Peptide.; Specificity unclear
YP_931636.1	Probable tautomerase lin2709 (EC 5.3.2.2). TREMBL:Q7UE84: 67% identity, 86% similarity InterPro:IPR004370; Taut. ProDom: PD404143 InterPro: 4-oxalocrotonate tautomerase taut: 4-oxalocrotonate tautomerase No signal peptide no TMH's; High confidence in function and specificity
YP_931637.1	Transcriptional regulator, LysR family,; Specificity unclear
YP_931638.1	Branched-chain amino acid aminotransferase (EC 2.6.1.42) (BCAT). Acts on leucine isoleucine and valine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity
YP_931639.1	Hypothetical response regulator, TREMBL: trembl|Q7MSI2 (24% Wolinella succinogenes, hypothetical protein ws0414) InterPro: IPR001610 PAC. IPR000014 PAS. IPR001789 Response_reg. IPR000160 GGDEF. Pfam: PF00990 GGDEF domain. PF00072 Response_reg. PF00785 PAC. PF00989 PAS. TIGRFAM: TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box.; Conserved hypothetical protein
YP_931640.1	Putative response regulator
YP_931641.1	Putative hybrid sensor and regulator protein
YP_931642.1	Aliphatic amidase expression-regulating protein,AmiC regulates the expression of the inducible aliphatic amidase activity in Pseudomonas aeruginosa. Similar to sprot|AMIC_PSEAE (31%) and to trembl|P74390 (50%).Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_931643.1	Conserved hypothetical protein.Similarity to b.subtilis bmru and to synechocystis pcc 6803 sll0036. Identities = 29/85 (34%) Entry name SWISSPROT:YEGS_ECOLI Prim. accession # P76407 InterPro IPR005218; Cons_hypoth147. IPR001206; DAGKc. Pfam PF00781; DAGKc; 1. Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0
YP_931644.1	Serine/threonine (S/T) phosphatases catalyse the dephosphorylation of phosphoserine and phosphothreonine residues. In mammalian tissues four different types of PP have been identified and are known as PP1, PP2A, PP2B and PP2C. Except for PP2C, these enzymes are evolutionary related. The catalytic regions of the proteins are well conserved TREMBL:Q7VZQ9: 41% identity, 50% similarity InterPro:IPR004843; M-ppestrase. Pfam:PF00149; Metallophos InterPro: Serine/threonine specific protein phosphatase No transmembrane helices sbcd: exonuclease SbcD; High confidence in function and specificity
YP_931645.1	Conserved hypothetical protein. Homology to an orf of Ralstonia eutropha of 61% (ZP_00167955). No domains predicted. No TMHs. No signal peptide.
YP_931646.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_931647.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_931648.1	putative chromosome partitioning protein; High confidence in function and specificity
YP_931649.1	Hypothetical protein MJ0435. trembl:Q8DGT1:51% identity, 64% similarity InterPro: IPR002934; NTP_transf. Pfam: PF01909; NTP_transf_2 No signal peptide (Signal P predicted) No transmembrane helices (TMHMM predicted). hstdl_phs_rel: histidinol phosphatase-r; Specificity unclear
YP_931650.1	Conserved hypothetical secreted protein. Homology to TLL2231 of Thermosynechococcus elongatus of 34% (tremble:Q8DGT2). Signal peptide present. No TMH reported present. Has (IPR008201)PF01934 Protein of unknown function DUF86;The function of members of this family is unknown.; Conserved hypothetical protein
YP_931651.1	Probable chromosome partitioning protein,; High confidence in function and specificity
YP_931652.1	Conserved hypothetical membrane protein. Homology to RS05051 of Ralstonia solanacearum of 45% (trembl|Q8Y1A4(SRS)). TMHMM2 reporting the presence of 26 TMH's. Signal P reporting Signal Peptide present. Coils2 program reporting presence of Coiled coil.; Conserved hypothetical protein
YP_931653.1	Similar to the Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-gpe acyltransferase); acyl-acyl carrier protein synthetase (acyl-acp synthetase)].Plays a role in lysophospholipid acylation. 25% Acyltransferase.IPR000873; AMP-bind. Pfam:PF01553; Acyltransferase; 1.PF00501; AMP-binding; 1. TMhelix:10; Function unclear
YP_931654.1	tremblnew|AAR36422:35% identity, 46% similarity EMBL:AE017218; AAR36422.1; TIGR:GSU3030; This Fe2+-requiring enzyme plays a role in D-glucuronate catabolism in Escherichia coli. Mannonate dehydratase converts D-mannonate to 2-dehydro-3-deoxy-D-gluconate. An apparent equivalog is found in a glucuronate utilization operon in Bacillus stearothermophilus T-6. Interpro:IPR004628;Man_dehyd SignalP predicted signal peptide present. No. of transmembrane helices: 1 (TMHMM predicted) pyrC_dimer: dihydroorotase homodimeric; Specificity unclear
YP_931655.1	AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Acyltransferase. TIGRFAM (TIGR00530): 1-acyl-sn-glycerol-3-phosphate acyltransferases. SignalP reporting signal peptide.; High confidence in function and specificity
YP_931656.1	Putative transcriptional repressor,; High confidence in function and specificity
YP_931657.1	Conserved hypothetical membrane protein. Homology to BB4612 of Bordetella bronchiseptica of 37% (trembl|Q7WEM2(SRS)). No domains predicted. signal peptide 3 TMHs; Conserved hypothetical protein
YP_931658.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_931659.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_931660.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_931661.1	putive ATP synthase delta chain. Homology to atpH of E. coli of 32% (sprot|ATPD_ECOLI). Key component of the F-type ATPases (EC 3.6.3.14). The ATPase has 2 components,CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha, beta,gamma, delta, epsilon. CF(0) has three main subunits: a, b and c. Subunit delta seems to be part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) into CF(1) or is implicated in proton conduction. InterPro: ATP synthase delta (OSCP) subunit (IPR000711) Pfam: ATP synthase delta (OSCP) subunit no signal peptide no TMHs; High confidence in function and specificity
YP_931662.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_931663.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_931664.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_931665.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_931666.1	Conserved hypothetical protein. Homology to rsc0460 of R. solanacearum of 39% (trembl|Q8Y276(SRS) Pfam: DUF1243 This family consists of a number of hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown. no signal peptide no TMHs
YP_931667.1	Ubiquinone/menaquinone biosynthesis methyltransferase ubiE (EC 2.1.1.-). Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-14-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-14-benzoquinol (DMQH2) (By similarity). InterPro: ubiE/COQ5 methyltransferase hemK_rel_arch: methylase putative; High confidence in function and specificity
YP_931668.1	Conserved hypothetical protein. Homology to rs04443 of R. solanacearum of 69% (trembl|Q8Y279). Pfam: PF06155,Protein of unknown function (DUF971) Interpro: IPR010376; This family consists of several short bacterial proteins and one sequence (Q8RZ62) from Oryza sativa. The function of this family is unknown. No Signal Peptide. No TMH present.
YP_931669.1	Phosphate regulon transcriptional regulatory protein,; High confidence in function and specificity
YP_931670.1	Phosphate regulon sensor protein, 3 Signal P reporting signal peptide TMHMM reporting 1 transmembrane helices. MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM PHOR/PHOB INVOLVED IN THE PHOSPHATE REGULON GENES EXPRESSION. PHOR MAY FUNCTION AS A MEMBRANE-ASSOCIATED PROTEIN KINASE THAT PHOSPHORYLATES PHOB IN RESPONSE TO ENVIRONMENTAL SIGNALS.; High confidence in function and specificity
YP_931671.1	Conserved hypothetical protein. Homology to ebA3023 of Azoarcus sp. EbN1 of 61% (trembl:Q5P4D4). No domains predicted. No TMHs. No signal peptide.
YP_931672.1	55% HIT. Pfam:PF01230; HIT; 1. The Histidine Triad (HIT) motif, His-phi-His-phi-His-phi-phi (phi, a hydrophobic amino acid) was identified as being highly conserved in a variety of organisms.
YP_931673.1	Conserved hypothetical glutamine amidotransferases class-II (Gn-AT), YafJ-type. Homology to ebA3026 of Azoarcus sp. EbN1 of 75% (gnl|keqq|eba:ebA3026(KEGG)). Pfam: Glutamine amidotransferases class-II. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has an Ntn hydrolase; Conserved hypothetical protein
YP_931674.1	Conserved hypothetical secreted protein. Homology to bll7463 of B. japonicum of 30% (tremble:Q89DH6). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_931675.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_931676.1	Conserved hypothetical secreted protein. Homology to an orf of Dechloromonas aromatica of 41% (gi|46141061|ref|ZP_00152875.2|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide present. NO TMH present.; Conserved hypothetical protein
YP_931677.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_931678.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_931679.1	functions in MreBCD complex in some organisms
YP_931680.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_931681.1	Rod shape-determining protein mreD. Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.; High confidence in function and specificity
YP_931682.1	Penicillin-binding protein 2 (PBP-2). CELL WALL FORMATION; PBP2 IS RESPONSIBLE FOR THE DETERMINATION OF THE ROD SHAPE OF THE CELL. ITS SYNTHESIZE CROSS- LINKED PEPTIDOGLYCAN FROM THE LIPID INTERMEDIATES. InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity
YP_931683.1	Rod shape-determining protein rodA. THIS IS ONE OF THE PROTEINS RESPONSIBLE FOR THE ROD SHAPE OF THE CELL. IT IS REQUIRED FOR THE EXPRESSION OF THE ENZYMATIC ACTIVITY OF PBP2 WHICH IS THOUGHT TO SYNTHESIZE PEPTIDOGLYCAN IN THE STEP OF INITIATION OF CELL ELONGATION.; High confidence in function and specificity
YP_931684.1	RlpA-like protein precursor.; Function unclear
YP_931685.1	Probable D-alanyl-D-alanine carboxypeptidase. Homology to dacD of E. coli of 41% (sprot|DACD_ECOLI) Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Pfam: D-alanyl-D-alanine carboxypeptidase signal peptide no TMHs; High confidence in function and specificity
YP_931686.1	D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity
YP_931687.1	Conserved hypothetical protein. Homology to RSC0326 of Ralstonia solanacearum of 53% (tremble:Q8Y2K9) Has PF04359;Protein of unknown function (DUF493);This family includes several proteins of uncharacterised function. InterPro;IPR007454 No Signal Peptdie or TMH present.
YP_931688.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
YP_931689.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_931690.1	Conserved hypothetical secreted protein. Homology to PP1518 of P. putida of 54% (trembl|Q88MQ2(SRS) No domains predicted Signal P reporting signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_931691.1	ATP-dependent DNA helicase rep (EC 3.6.1.-). REP HELICASE IS A SINGLE-STRANDED DNA-DEPENDENT ATPASE INVOLVED IN DNA REPLICATION; IT CAN INITIATE UNWINDING AT A NICK IN THE DNA. IT BINDS TO THE SINGLE-STRANDED DNA AND ACTS IN A PROGRESSIVE FASHION ALONG THE DNA IN THE 3 TO 5 DIRECTION (BY SIMILARITY). InterPro: UvrD/REP helicase.; High confidence in function and specificity
YP_931692.1	Conserved hypothetical cytochrome c5. Homology to vc0168 of V. cloreae of 38% (tremble: Q9KVH8). This basic c-type monoheme cytochrome has an unusally low redox potential compaired with mitochaondrial cytochrome C. It is reactive with cytochrome c oxidase but not with reductase. Pfam: Cytrochrome C probable signal peptide no TMHs; Family membership
YP_931693.1	Putative benzil reductase. Homology to yueD of B. cereus of 32% (trembl|Q8RJ14). Belongs to the short-chain dehydrogenases/reductases (SDR) family. Transform benzil to (S)-benzion. Interpro: short-chain dehydrogenase/reductase SDR (IPR002198) Pfam: short chain dehydrogenase (PF00106) no signal peptide no TMHs; Family membership
YP_931694.1	Conserved hypothetical protein. Homology to an orf of R. oxalatica of 31% (trembl|Q84ES1). Pfam: 37-kD nucleoid-associaed bacterial protein The Escherichia coli nucleoid contains DNA in a condensed but functional form. Analysis of proteins released from isolated spermidine nucleoids after treatment with DNase I reveals significant amounts of two proteins not previously detected in wild-type Escherichia coli. Partial amino-terminal sequencing has identified them as the products of rdgC and yejK. no signal peptide no TMHs
YP_931695.1	Entry name TREMBL:Q988L8 Prim. accession # Q988L8 InterPro IPR002539; MaoC_dehydratas. Identities = 63/131 (48%) Pfam PF01575; MaoC_dehydratas; 1. Number of predicted TMHs: 0 Probable MaoC protein (Phenylacetic acid degradation protein paaZ).
YP_931696.1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). apbA_panE: 2-dehydropantoate 2-reductase; Function unclear
YP_931697.1	Probable protein-disulfide reductase. Homology with trxC of E. coli of 45% (AAB88587). Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. InterPro: Thioredoxin Tigrfam: redox_disulf_1: redox-active disulfide Pfam: Thioredoxin no TMHs no signal peptide; Family membership
YP_931698.1	Putative trans-acting regulatory protein. Homology to hvrA of R. capsulatus of 27% (sprot|HVRA_RHOCA). The histone-like nucleoid-structuring (H-NS) protein belongs to a family of bacterial proteins that play a role in the formation of nucleoid structure and affect gene expression under certain conditions (e.g. light). Interpro: Histone -like nucleotide-structuring protein H-Ns (IPR001801) Pfam: H-NS histone family no signal peptide no TMHs; Family membership
YP_931699.1	Conserved hypothetical secreted protein. Homology to CV3728 of Chromobacterium violaceum of 57% (tremble:Q7NRQ2) No domains predicted. No TMHs signal peptide present; Conserved hypothetical protein
YP_931700.1	Conserved hypothetical transcription factor,; Conserved hypothetical protein
YP_931701.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide. 1 TMHs
YP_931702.1	Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear
YP_931703.1	Exonuclease sbcD homolog. Probably involved in genetic recombination. InterPro: DNA repair exonuclease. sbcd: exonuclease SbcD.; High confidence in function and specificity
YP_931704.1	Nuclease sbcCD subunit C. SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity (By similarity). sbcc: exonuclease SbcC.; High confidence in function and specificity
YP_931705.1	Arylesterase (EC 3.1.1.2) (Aryl-ester hydrolase) pir:C75401:39% identity, 52% similarity:hydrolase-related protein - Deinococcus radiodurans . IS A BIFUNCTIONAL ENZYME CAPABLE OF BOTH ESTER HYDROLYSIS AND HALOGENATION. ACTS ON MANY PHENOLIC ESTERS. Pfam: PF00561: alpha/beta hydrolase fold (74-271) InterPro: IPR000073: Alpha/beta hydrolase fold IPR000379: Esterase/lipase/thioesterase Pfam:Zn binding dehydrogenase mobB: molybdopterin-guanine dinucleotid; Family membership
YP_931706.1	Conserved hypothetical protein. Homology only to r01975 of S. meliloti of 31% (trembl|Q92P21). no signal peptide no TMHs
YP_931707.1	TREMBL:Q82XH5: 33% identity, 44% similarity InterPro:IPR007404; DUF457. Pfam: PF04307; DUF457 fnt: formate/nitrite transporter Non-secretory protein with signal peptide probability of 0.391 TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein
YP_931708.1	Description:abc transporter periplasmic binding protein.This is a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria. All of these proteins are outer membrane proteins and are thus antigenic in nature when possessed by the pathogenic members of the family Probable CD4+ T cell-stimulating antigen precursor. TREMBL: Q8XXD8: 64% identity, 79% similarity InterPro:IPR003760; Bmp. Pfam: PF02608; Bmp Secretory protein with high signal peptide probablity (Signal P predicted). No. of transmembrane helices: 1 (TMHMM predicted) prok_nadp_idh: isocitrate dehydrogenas; Specificity unclear
YP_931709.1	Hippurate hydrolase (EC 3.5.1.32) (Benzoylglycine amidohydrolase) (Hippuricase). TREMBL:Q7VUP2: 43% identity, 57% similarity InterPro; IPR002933; Peptidase_M20. InterPro; IPR010168; Pept_M20D_amidh. Pfam; PF01546; Peptidase_M20; 1. TIGRFAMs; TIGR01891; amidohydrolases TIGR00003: copper-ion-binding protein No signal peptide (Signal P predicted) No transmembrane helices present; High confidence in function and specificity
YP_931710.1	Putative AraC-family transcriptional regulator,; Family membership
YP_931711.1	Conserved hypothetical protein. Homology to bb1472 of B. bronchiseptica of 46% (trembl|Q7WMC0). Interpro: Protein of unknown function DUF861 (IPR008579). Pfam: Cupin_3 (former DUF861) (PFO5899). This family consists of several proteins which seem to be specific to plants and bacteria. The function of this family is unknown. No signal peptide. No TMHs
YP_931712.1	Hypothetical protein, 45% identity to TrEMBL;Q7U8P5. Weak Homology with hits. No domains,repeats, motifs or features predicted Present.; Function unclear
YP_931713.1	Sarcosine oxidase,subunit beta counts to the FAD dependent oxidoreductases. Similar to trembl|Q88AX8 (49%) and to trembl|Q987J9 (43%). Pfam (PF01266): FAD dependent oxidoreductase Pfam (PF01494): FAD binding domain Pfam (PF00070): Pyridine nucleotide-disulphide oxidoreductase; Function unclear
YP_931714.1	Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership
YP_931716.1	Probable proline dehydrogenase transcriptional activator. Similar to sprot|PUTR_AGRTU (31% Agrobacterium tumefaciens, proline dehydrogenase transcriptional activator prp or putR) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_931717.1	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (78-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). bioA: adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Specificity unclear
YP_931718.1	Conserved hypothetical acetyltransferase. Homology to putative acetaltransferase (GNAT family) of P. syringae of 42% (trembl|Q88AY8). Pfam: Acetyltransferase (GNAT) family no signal peptide no TMHs; Family membership
YP_931719.1	Putative aldehyde dehydrogenase (NAD+) (EC 1.2.1.3). Homology to adlH of E. coli of 35% (sprot|DHAL_ECOLI). Aldehyde dehydrogenases (EC: 1.2.1.3 and EC: 1.2.1.5) are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity
YP_931720.1	Probable 2-haloalkanoic acid dehalogenase (EC 3.8.1.2) (L-2-haloacid dehalogenase) (Halocarboxylic acid halidohydrolase). TREMBL:Q92Y68: 68% identity, 82% similarity These proteins catalyze the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids [1]. They belong to the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases InterPro:IPR006328; HAD_II. IPR006388; HAD_SF_IA_v2. IPR005834; Hydrolase. Pfam PF00702; Hydrolase rpiB_lacA_lacB: sugar-phosphate isomer No signal peptide No transmembrane helices; High confidence in function and specificity
YP_931721.1	This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase,Sarcosine oxidase beta subunit, D-alanine oxidase, D-aspartate oxidase. Similar to trembl|Q88AY5 (61%) and to sprot|ORDL_ECOLI (32%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site; Family membership
YP_931722.1	Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide periplasmic-binding protein dppA in E.coli. DIPEPTIDE-BINDING PROTEIN OF AN OSMOTIC-SHOCKABLE TRANSPORT SYSTEM. DPPA IS ALSO REQUIRED FOR PEPTIDE CHEMOTAXIS. InterPro: Bacterial extracellular solute-binding protein family 5 Signal peptide; Specificity unclear
YP_931723.1	Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease, DppB in E.coli.; Specificity unclear
YP_931724.1	Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease, DppC in E.coli.; Specificity unclear
YP_931725.1	Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide transport membrane protein, DppD in E.coli Probably responsible for energy coupling to the transport system.; Specificity unclear
YP_931726.1	Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of R. eutropha of 68% (AAF19796). Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity
YP_931727.1	Conserved hypothetical secreted protein. Homology to an orf of Polaromonas sp. JS666 of 34% (ZP_00360285) . No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_931728.1	Hypotethical outer membrane efflux protein. Homology to PA2525 of P. aeruginosa of 25%. signal peptide. no TMHs
YP_931729.1	Hypothetical secreted protein. No homology to the data bank no domains predicted signal peptide no TMHs
YP_931730.1	Conserved hypothetical secreted protein. Homology to cc1787 of C. crescentus of 30% (trembl|Q9A7D6) no domains predicted signal peptide no TMHs; Conserved hypothetical protein
YP_931731.1	Cobalt-zinc-cadmium resistance protein CzcA (cation efflux system protein CzcA). In A.eutrophus has a low cation transport activity for cobalt, it is essential for the expression of cobalt, zinc, and cadmium resistance.Czca and Czcb together would act in zinc efflux nearly as effectively as the complete czc efflux system (czcABC).Belongs to the acrb/acrd/acrf family. 41% similarity to the A.eutrophus CzcA protein. SWISSPROT:CZCA_ALCEU:P13511 InterPro: Heavy metal efflux pump CzcA. InterPro:IPR001036; Acrflvin_res.IPR004763: CzcA. Pfam:PF00873; ACR_tran; 1. InterPro:TIGR00914:Heavy metal efflux pump CzcA InterPro:PF00873:Acriflavin resistance protein Signal peptide: present.; High confidence in function and specificity
YP_931732.1	Hypothetical protein, 32% identity to TrEMBL;Q82T66 No Signal Peptide/Features/Domains/TMH detected.
YP_931733.1	In E.coli this receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Binding of T5 triggers the opening of a high conductance ion channel. Can also transport the antibiotic albomycin. Signal peptide.; Specificity unclear
YP_931734.1	Conserved hypothetical secreted protein. Homology to RPA1846 of R.palustris of 39% (trembl:Q6N8Q7). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_931735.1	Conserved hypothetical membrane protein. Homology to SO1157 of Shewanella oneidensis of 50% (trembl|Q8EHR0(SRS)). No domains predicted. Signal peptide. 7 TMHs; Conserved hypothetical protein
YP_931736.1	Putative biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 35%. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. PFam: MotA/TolQ/ExbB proton channel family signals peptide most probable 4 TMHs; Family membership
YP_931737.1	putative biopolymer transport protein ExbD. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton grandient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership
YP_931738.1	Putative biopolymer transport protein ExbD. Homology to exbD2 of X. campestris of 36% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership
YP_931739.1	Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi|47575633|ref|ZP_00245668.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein
YP_931740.1	Adenosine deaminase (Adenosine aminohydrolase). InterPro: Adenosine and AMP deaminase; High confidence in function and specificity
YP_931741.1	Putative NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog). Modulates the activities of several enzymes which are inactive in their acetylated form. Similar to SWISSPROT: sprot|NPD_AERPE (27% Aeropyrum pernix, NpdA or aq_2170) Pfam: PF02146 Sir2 family.; High confidence in function and specificity
YP_931742.1	Hypothetical membrane protein no homology to the data bank no domains predicted no signal predicted 7 TMHs
YP_931743.1	Hypothetical protein, showing only very low similarity to known proteins (SWISSPROT: sprot|FRAH_ANASP; >10% Anabaena sp., FraH). Important Domains are: Pfam: PF00034 Cytochrome c. SMART: SM00438 ZnF_NFX TMHMM reporting 1 transmembrane helices.
YP_931744.1	Putative ABC transporter periplasmic binding protein, DctP: TRAP dicarboxylate transporter.Binds C4-dicarboxylates; part of the binding-protein- dependent transport system for uptake of c4-dicarboxylates. 28% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide:present. TMhelix:1; Specificity unclear
YP_931745.1	C4-dicarboxylate transport system,permease small protein,DctQ. The Dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 22% DctQ. Pfam:PF04290; DctQ; 1. TMHelix:4.; High confidence in function and specificity
YP_931746.1	TRAP-type C4-dicarboxylate transport system, large permease component, DctM.The Dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 34% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. Signal peptide: present. TMhelix:11.; Specificity unclear
YP_931747.1	Putative TetR family transcriptional regulator,; Family membership
YP_931748.1	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q8XRL2 (55% identity); SWISSPROT:P31223 (53% identity). Pfam (PF00529): HlyD family secretion protein. SignalP predicting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership
YP_931749.1	Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q8E8H2 (65% identity); SWISSPROT:P31224 (63% identity). InterPro (IPR001036): Acriflavin resistance protein. InterPro (IPR004764): Hydrophobe/amphiphile efflux-1 HAE1. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. Pfam (PF00873): AcrB/AcrD/AcrF family. TMHMM reporting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear
YP_931750.1	Probable outer membrane efflux protein. Homology to oprM of P. aeruginosa of 57%. Component of an efflux system that confers multidrug or multible antibiotic resistence. Pfam: Outer membrane efflux protein signal peptide no TMHS; Family membership
YP_931751.1	Bacterioferritin (BFR) (Cytochrome B-1) (Cytochrome B-557). In E. coli is an iron-storage protein consisting of 24 identical subunits that pack together to form a highly symmetrical, nearly spherical shell surrounding a central cavity of about 8 nm diameter.X-ray crystallographic studies have revealed a close structural similarity between BFR and the ferritins, a family of iron-storage proteins found in both eukaryota and prokaryota. Key role in iron homeostasis. InterPro: Bacterioferritin. Non-secretory protein; High confidence in function and specificity
YP_931752.1	Probable dnaK suppressor protein,; High confidence in function and specificity
YP_931753.1	Hypothetical protein. No homology to the data bank. No domains predicted. No signal peptide. No TMHS
YP_931754.1	Hypothetical flavodoxin reductase. Homology to the N-terminal part of bb4317 of B. bronchisptica of 40% (trembl|Q7WFF6). InterPro: Oxidoreductase FAD and NAD(P)-binding domain ((IPR001433); NADH: cytochrome b5 reductase (CBR) (IPR001834) Pfam: Oxidorectase FAD-binding domain; Oxidoreductase NAD-binding domain no signal peptide no TMHs
YP_931755.1	Conserved hypothetical membrane protein, 38% similarity to trEMBL;Q7WDT1,Putative membrane protein [BB4906] [Bordetella bronchiseptica (Alcaligenes bronchisepticus)]. TMHMM2 predicts 6 TMH's present. No signal peptide present.; Family membership
YP_931756.1	conserved hypothetical protein, 54% identity to TrEMBL;Q9JYD1 Hypothetical protein NMB1644 [NMB1644] [Neisseria meningitidis(serogroup B)]. Has PF00009:Elongation factor Tu GTP binding domain:IPR000795 ProtSyn_GTPbind: This domain contains a P-loop motif, also found in several other families such as Ras, Arf and Myosin_head. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains. Elongation factors belong to a family of proteins that promote the GTP-dependent binding of aminoacyl tRNA to the A site of ribosomes during protein biosynthesis,and catalyse the translocation of the synthesised protein chain from the A to the P site. The proteins are all relatively similar in the vicinity of their C-termini, and are also highly
YP_931757.1	Conserved hypothetical protein. Homology to MCA0921 of Methylococcus capsulatus of 54% (trembl:Q60AE3). N domains predicted. No TMHs. NO signal peptide.
YP_931758.1	Conserved polysaccharide deacetylase. Homology to rs03397 of R. solanacearum of 62% (trembl|Q8Y2A8). Interpro: Polysaccharide deacetylase (IPR002509). Pfam: Polysaccharide deacetylase (PF01522). The family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast, and endoxylanases which hydrolyses glucosidic bonds in xylan. No signal peptide. No TMHs; Conserved hypothetical protein
YP_931759.1	Hypothetical protein. No good homology to the data bank. No domains predicted. No TMHs. No signal peptide.
YP_931760.1	Conserved hypothetical membrane protein. Homology to rsc0429 of R. solanacearum of 52% (trembl|Q8Y2A7). Tigrfam: 2A0604s01: protein-export membrane protein signal peptide 10 TMHs; Function unclear
YP_931761.1	Conserved hypothetical secreted protein. Homology to RS03399 of R. solanacearum of 47% (trembl|Q8Y2A6(SRS)) No domains predicted. Signal Peptide present. No TMH reported.; Conserved hypothetical protein
YP_931762.1	Conserved hypothetical acetyltransferase. Homology to rsc0431 of R. solanacearum of 61% (trembl|Q8Y2A5) Pfam: Bacterial lipid A biosynthesis acetyltransferase no signal peptide no TMHs; Conserved hypothetical protein
YP_931763.1	Conserved hypothetical protein. Homology to xac 4098 of X. axonapodis of 36% (trembl|Q8PF87). No domains predicted. No signal peptide. No TMHs.
YP_931764.1	Entry name:- TREMBL:Q87EI7 InterPro:- IPR000873; AMP-bind. Pfam:- PF00501; AMP-binding; 2. Identity :- 45% Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0
YP_931765.1	Conserved hypothetical membrane protein. Homology to rsc3402 of R. solanacearum of 46% (trembl|Q8Y2A3(SRS)) no domains predicted signal peptide 5 TMHs; Conserved hypothetical protein
YP_931766.1	Similar to TREMBL:Q9PFA7 (61% identity); TREMBL:Q87AD9 (61% identity); SWISSPROT:Q7VKH6 (34% identity).; Function unclear; ORF1
YP_931767.1	Probable sensor protein,; High confidence in function and specificity
YP_931768.1	Transcriptional regulatory protein,; High confidence in function and specificity
YP_931769.1	Conserved hypothetical secreted protein. Homology to bd0091 of B. bacteriovorus of 52% (tremblnew|CAE77770(SRS)). no domains predicted. signal peptide. no TMHs.; Conserved hypothetical protein
YP_931770.1	Conserved hypothetical cytochrome b561 family protein. Homology to rsc2354 of R. solanacearum of 43% (trembl|Q8XWW6). Involved in electron transfer from hydrogen to oxygene. Pfam: Nickel-dependen hydrogenase b-type cytochrome no signal peptide probable 4 TMHs; Family membership
YP_931771.1	Putative membrane fusion protein. Homology to cnrb of A. eutrophus of 30% (pir|F47056). Proteins of the MFP family function as auxiliary proteins or 'adaptors',connecting a primary porter in the cytoplasmic membrane of a Gram-negative bacterium with an outer membrane factor protein that serves a porin or channel function in the outer membrane. In A. eutrophus is this protein involved in cobalt and nickel resistance. No domains predicted. No signal peptide No TMHs; Family membership
YP_931772.1	Cobalt-zinc-cadmium resistance protein CzcA (cation efflux system protein CzcA). In A.eutrophus has a low cation transport activity for cobalt, it is essential for the expression of cobalt, zinc, and cadmium resistance.Czca and Czcb together would act in zinc efflux nearly as effectively as the complete czc efflux system (czcABC).Belongs to the acrb/acrd/acrf family. 41% similarity to the A.eutrophus CzcA protein. SWISSPROT:CZCA_ALCEU:P13511 InterPro: Heavy metal efflux pump CzcA. InterPro:IPR001036; Acrflvin_res.IPR004763: CzcA. Pfam:PF00873; ACR_tran; 1. InterPro:TIGR00914:Heavy metal efflux pump CzcA InterPro:PF00873:Acriflavin resistance protein Signal peptide: present.; High confidence in function and specificity
YP_931773.1	Conserved hypothetical protein.30% identical to TrEMBL; Q89MS9. Signal Peptide present.
YP_931774.1	Hypothetical secreted protein. Homology to cnfc of Ralstonia sp CH34 of 28% (tremblnew|CAB82451(SRS). Pfam: outer membrane protein. Interpro: Type I antifreeze protein (IPR000104). singal peptide. no TMHs
YP_931775.1	Conserved hypothetical protein. Homology to Daro03000974 of Dechloromonas aromatica of 68% (gi|46140980|ref|ZP_00152750.2|(NBCI ENTREZ)). Pfam: Elongator protein 3, MiaB family, Radical SAM. This superfamily contains MoaA, NifB, PqqE, coproporphyrinogen III oxidase, biotin synthase and MiaB families, and includes a representative in the eukaryotic elongator subunit, Elp-3. Some members of the family are methyltransferases; Pfam: B12 binding domain. This domain binds to B12 (adenosylcobamide), it is found in several enzymes, such as glutamate mutase Q05488, methionine synthase Q99707 and methylmalonyl-CoA mutase. no signal peptide. no TMHs
YP_931776.1	Hypothetical protein. No homology to protein of similar size in the data bank. No domains predicted. No signal peptide. No TMHs
YP_931777.1	Putative RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ.; High confidence in function and specificity
YP_931778.1	Conserved hypothetical secreted protein. Homology to XCC0845 of X. campestris of 30% (trembl|Q8PC89). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein
YP_931779.1	Conserved hypothetical secreted protein. Homology to CC3220 of Caulobacter crescentus of 34% (trembl|Q9A3I4(SRS)) No domains predicted. Signal Peptide present. NO TMH present.; Conserved hypothetical protein
YP_931780.1	Putative Hypothetical protein. No Good homologous hits in the DB. No domains/features/signal peptide or motifs present.
YP_931781.1	Hypothetical protein. Weak Homology. 39% identity to TrEMBL;Q8EWG7. No domains, repeats, motifs or features present.
YP_931782.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide. 1 TMHs
YP_931783.1	Conserved hypothetical protein. Homology to BB1132 of B.bronchiseptica of 42% (tremble:Q7WNA8). No domains predicted. No Signal peptide or TMH present.
YP_931784.1	Conserved hypothetical membrane protein. Homology to rs03062 of R. solanacearum of 48% (tremble:Q8XQ05) no domains predicted signal peptide 2 TMHs; Conserved hypothetical protein
YP_931785.1	Outer membrane protein A precursor. Homology with hypothetical transmembrane protein and probable outer membrane protein of 56% as well as with motB (flagellar motor protein B) from amino acid 84 of 34%. Pfam: OmpA no signal peptide probable 1 TMH; Conserved hypothetical protein
YP_931786.1	Conserved hypothetical protein. Homology to RS03060 of R.solanacearum of 35% (tremble:Q8XQ03) No domains predicted. No signal peptide or TMH present.
YP_931787.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no TMHs. no signal peptide
YP_931788.1	Pfam (PF02801): Beta-ketoacyl synthase, C-terminal domain. Pfam (PF00109): Beta-ketoacyl synthase, N-terminal domain.; Function unclear
YP_931789.1	Conserved hypothetical acyl carrier protein. Homology to psptO5093 of P. syringae of 44% (trembl|Q87V48). Interpro: Phosphopanteteine-binding (IPR00613). Pfam: Phosphopantetheine attachment site (PF00550) Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. Tigrfam: acyl_carrier: acyl carrier protein. no signal peptide. no TMHs; Conserved hypothetical protein
YP_931790.1	Similar to TREMBL:Q7NFQ1 (27% identity); TREMBL:Q97E48 (20% identity); TREMBL:Q8FWI9 (21% identity). TMHMM predicting six transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear
YP_931791.1	Probable DNA mismatch repair protein mutS. TREMBL:Q92SQ4:42% identity, 55% similarity. InterPro:IPR002716; PIN. Pfam: PF01850; PIN Absence of signal peptide Absence of transmembrane helices L17: ribosomal protein L17; Function unclear
YP_931792.1	no significant homologies
YP_931793.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8R788 (35% identity); TREMBL:Q81S77 (37% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership
YP_931794.1	Conserved hypothetical protein. Homology to Daro03001929 of Dechloromonas aromatica of 68% (gi|53730629|ref|ZP_00348881.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_931795.1	Conserved hypothetical protein. Homology to Daro03001928 of Dechloromonas aromatica of 59% (gi|41724574|ref|ZP_00151411.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_931796.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; this condensing enzyme differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_931797.1	Probable dialkylrecorsinol condensing enzyme. Homology to darA of P. aurantiaca of 56% (trembl|Q84H30(SRS)) no domains predicted no signal peptide 1 TMHs; Family membership
YP_931798.1	INVOLVED IN CELL WALL BIOSYNTHESIS AND MAY ALSO ACT AS A SENSOR OF EXTERNAL PENICILLINS, TREMBL:Q7UMP8 (30% identity); TREMBL:Q988N4 (27% identity).; Family membership
YP_931799.1	Conserved hypothetical protein. Homology to CV2374 of C.violaceum of 31% (tremble:Q7NVG9). No domains predicted. No signal peptide or TMH present.
YP_931800.1	InterPro:IPR001279- Metallo-beta-lactamase superfamily,glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. TREMBL:Q7WEK1-55% Identity. Pfam-Presence of phosphoribosyltransferase, tissue factor, and GMP reductaseC like domains Signal P predicting signal peptide and TMHMM predicting transmembrane helices. ccoP: cytochrome c oxidase cbb3-type s; High confidence in function and specificity
YP_931801.1	Conserved hypothetical protein, 66% similarity to TrEMBL; Q6NA86. Signal peptide present. No TMH reported present.
YP_931802.1	pathway:carnitine metabolism (conversion of carnitine to gamma-butyrobetaine). TREMBL:Q9F9V3: 71% identity, 83% similarity similarity:belongs to the transferase hexapeptide repeat family Carnitine operon protein caiE. InterPro:IPR001451; Hexapep_transf. Pfam:PF00132; Hexapep InterPro: Bacterial transferase hexapeptide repeat TIGR00094: conserved hypothetical protein; High confidence in function and specificity
YP_931803.1	Conserved hypothetical dehydrogenase. Homology to paaZ of A. evansii of 83% (trembl|Q9F9V2). Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership
YP_931804.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_931805.1	converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation
YP_931806.1	Phenylacetic acid aerobic catabolism. Similar to TREMBL:Q9F9V0 (74% identity); SWISSPROT:P76084 (48% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050; High confidence in function and specificity
YP_931807.1	Phenylacetate-coenzyme A ligase (EC 6.2.1.30) (Phenylacetyl-CoA ligase) (PA-CoA ligase). catalyzes the activation of phenylacetic acid to phenylacetyl-coA; High confidence in function and specificity
YP_931808.1	with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA
YP_931809.1	with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation
YP_931810.1	Probable phenylacetic acid degradation protein PaaC. Homology to paaI of P. putida of 46% (trembl|O84983). Part of a catabolic pathway of phenylacetic acid. These proteins forms part of a dioxygenase complex. Interpro: Phenylacetic acid catabolic (IPR007814) Pfam: Phenylacetic acid catabolic protein (PF05138) no signal peptide no TMHs; High confidence in function and specificity
YP_931811.1	Probable pheylacetic acid degradation protein PaaD. Homology to phaH of P. putida of 54% (trembl|Q88HS8) Interpro: Protein of unknown function DUF59 (IPR002744) Pfam: Domain of unknoen function DUF59 (PF01883). Domain of unknown function DUF59;IPR002744; This family includes prokaryotic proteins of unknown function. The family also includes PhaH O84984 from Pseudomonas putida. PhaH forms a complex with PhaF O84982, PhaG O84983 and PhaI O84985,which hydroxylates phenylacetic acid to 2-hydroxyphenylacetic acid. So members of this family may all be components of ring hydroxylating complexes. no signal peptide no TMHs; High confidence in function and specificity
YP_931812.1	Probable phenylacetic acid degradation NADH oxidoreductase paaE. Homology to paaE of E. coli of 50% (sprot|PAAE_ECOLI). Probable PART OF A MULTICOMPONENT OXYGENASE involved in aerobic degradation of phenylacetic acid. InterPro: Oxidoreductase FAD and NAD(P)-binding domain(IPR001433); 2Fe-2S Ferredoxin (IPR006057); Ferredoxin (IPR001041); NADH: cytochrome b5 reductase (CBR) (IPR001834) Pfam: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_931813.1	Putative TetR family transcriptional regulator,; Family membership
YP_931814.1	catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA
YP_931815.1	ABC transporter substrate binding proteins count to the family of extracellular ligand binding proteins. It is a component of the high affinity amino acid transport system. Similar to trembl|Q8XU64 (71%) and to sprot|LIVJ_ECOLI (16%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_931816.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W5E8 (62%), to sprot|BRAD_PSEAE (25%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting nine Tmhelix.; Specificity unclear
YP_931817.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (54%) and to trembl|Q8UFI6 (47%). Pfam: ABC transporter Pfam (PF02653): Branched-chain amino acid transport system / permease component Smart : AAA ATPase SignalP reporting Signal peptide. TMHMM reporting nine Tmhelix.; Specificity unclear
YP_931818.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (68%) and to trembl|Q7WCY5 (63%). Smart: AAA ATPases; Specificity unclear
YP_931819.1	DNA-binding protein HU (DNA-binding protein II) (HB). Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it and thus to prevent its denaturation under extreme environmental conditions. InterPro: Bacterial histone-like DNA-binding protein; High confidence in function and specificity
YP_931820.1	ATP-dependent RNA helicase; Family membership
YP_931821.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_931822.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_931823.1	bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis
YP_931824.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_931825.1	Putative Protein disulfide-isomerase (EC 5.3.4.1). Homology to dsbD of E. coli of 37% (sprot|DSBD_ECOLI). Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity). Pfam: Cytochrom C biogenesis protein transporter signal peptide probable 8 TMHs; Family membership
YP_931826.1	Periplasmic divalent cation tolerance protein .36% similarity to E.coli CutA1 protein involved in copper tolerance. InterPro:IPR004323; CutA1. Pfam:PF03091; CutA1; 1.; High confidence in function and specificity
YP_931827.1	TREMBL:Q7MBF3: 80% identity, 89% similarity InterPro:IPR004136; 2nprop_dioxygen. IPR003009; FMN_enzyme. Pfam: PF03060; NPD tim: triosephosphate isomerase Non-secretory protein with no signal peptide. TMHMM predicted no transmembrane helices.; High confidence in function and specificity
YP_931828.1	Conserved hypothetical protein. Homology to GSU0176 of G.sulfurreducens of 42% (tremble:Q74GR9) No domains predicted. No signal peptide or TMH reported present.
YP_931829.1	Putative flavocytochrome protein. 48% FAD_binding_6.IPR001433; Oxred_FAD/NAD(P). Pfam:PF00970; FAD_binding_6; 1.PF00175; NAD_binding_1; 1. TMhelix: 6. Siganl peptide: present.; Function unclear
YP_931830.1	conserved hypothetical protein. Homology to cv0811 of C. violaceum of 43% (trembl|Q7NPT0(SRS) no domains predicted no signal peptide no TMHs
YP_931831.1	Putative TetR family transcriptional regulator,; Conserved hypothetical protein
YP_931832.1	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to sprot|LIVK_SALTY (23%) and to trembl|Q8XUX2 (46%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_931833.1	Conserved hypothetical protein. Homology to SCO5300 of Streptomyces coelicolor of 46% (tremble:Q9XAE9). No domains predicted. No TMHs. No signal peptide.
YP_931834.1	HTH-type transcriptional regulator blaA (Beta-lactamase regulatory protein blaA). Positive regulator of the expression of the gene (blab) for beta-lactamase. Similar to SWISSPROT: sprot|BLAA_PROVU (32% Proteus vulgaris, HTH-type transcriptional regulator BlaA) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_931835.1	Conserved hypothetical protein, 41% similarity to TrEMBL;Q88JC7. Has IPR005544 DUF_HHE:PF03794;Domain of Unknown function:This domain normally occurs as tandem repeats and is found in bacteria, yeast and plants. It contains two fully conserved histidines and one glutamate residue. Members of the family include DnrN, NorA and ScdA, which have been implicated in NO response and cell wall physiology. Has no Signal peptide or TMH reported present.
YP_931836.1	Hypothetical protein yqhO. This family consists of various patatin glycoproteins from the total soluble protein in potato tubers.Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalysing the cleavage of fatty acids from membrane lipids SPROT:P54513: 23% identity, 33% similarity SubtiList: BG11703; yqhO. InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin No signal peptide TMHMM predicted 2 transmembrane helices mobB: molybdopterin-guanine dinucleot; Family membership
YP_931837.1	Hypothetical protein Rv1063c/MT1093/Mb1092c. TREMBL:Q89EP5: 29% identity, 42% similarity InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin 2A0108: nitrate transporter Absence of signal peptide No. of TMH's: 2 (TMHMM predicted).; Family membership
YP_931838.1	Conserved hypothetical secreted protein. Homology to BPP2140 of Bordetella parapertussis 0f 44% (trembl|Q7W8J3(SRS)) No domains predicted. Signal peptide present. No TMH present. 6PTHBS: 6-pyruvoyl tetrahydrobiopterin; Conserved hypothetical protein
YP_931839.1	EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.; Conserved hypothetical protein
YP_931840.1	PAS/PAC/GGDEF-domain containing protein, suggesting involvement into signalling processes. Similarity to SWISSPROT: sprot|YDAM_ECOLI (24% Escherichia coli, hyp. protein) / TREMBL: trembl|Q887F0 (59% Pseudomonas syringae, hyp. protein) Pfam: PF00990 GGDEF domain. This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. The function of this domain is unknown, however it has been shown to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box.; Conserved hypothetical protein
YP_931841.1	Probable hypothetical Protein. Extremely weak homology with hits in the PDB. No Motif/Features/TMH/ or Signal peptide present.
YP_931842.1	38% Peri-phosph.IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR00975; 3a0107s03; 1. Signal peptide present.; High confidence in function and specificity
YP_931843.1	Conserved hypothetical membrane protein. Homology to an orf of Acinetobacter sp. (strain ADP1) of 43% (tremble:Q6F6W4). no domains predicted. signal peptide. 1 TMHs; Conserved hypothetical protein
YP_931844.1	Conserved hypothetical membrane protein. No homology to the data bank No domains predicted No signal peptide 2 TMHs
YP_931845.1	Putative cytochrome c'. Homology to cytochrome c of R. gelatineosus (sprot|CYCP_RHOGE). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN. InterPro: Cytochrome c class II (IPR002321) Pfam: Cytochrome C probable signal peptide no TMHs; Function unclear
YP_931846.1	Belongs to the arylamine n-acetyltransferase family. Arylamine N-acetyltransferase is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Similar to TREMBL:Q98D42 (47% identity); TREMBL:Q8FHI6 (39% identity); SWISSPROT:P77567 (39% identity). InterPro (IPR001447): N-acetyltransferase Pfam (PF00797): N-acetyltransferase.; High confidence in function and specificity
YP_931847.1	Sporulation initiation inhibitor protein soj. INHIBITS THE INITIATION OF SPORULATION SPO0J ANTAGONIZES THIS INHIBITION. SOJ ULTIMATELY INHIBITS THE ACTIVATION (PHOSPHORYLATION) OF SPO0A. IT IS NOT REQUIRED FOR CHROMOSOME PARTITIONING. InterPro: ParA family ATPase; Function unclear
YP_931848.1	Probable Hypothetical Protein. No domains,features,motifs, or signal peptide present.
YP_931849.1	ATP-dependent DNA helicase pcrA (EC 3.6.1.-). InterPro: UvrD/REP helicase; Specificity unclear
YP_931850.1	42% Na_H_porter.IPR004705; NaHantiport_bac.Bacterial Na+/H+ antiporter Pfam:PF00999; Na_H_Exchanger; 1. TIGRFAMs:TIGR00831; a_cpa1; 1. Signal peptide present TMHelix: 12; High confidence in function and specificity
YP_931851.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal P reporting Signal Peptide present. No TMH reported Present.
YP_931852.1	Prenyltransferase family protein. InterPro: UbiA prenyltransferase; Specificity unclear
YP_931853.1	Putative Small Multi-Drug resistant(SMR)family protein, 30% identical to TrEMBL;Q8XZS2. Has PF00893,Small Multidrug Resistance protein;IPR000390, Smr:This family is the Small Multidrug Resistance (SMR) family. Several members have been shown to export a range of toxins, including ethidium bromide and quaternary ammonium compounds, through coupling with proton influx.
YP_931854.1	Conserved hypothetical secreted protein. Homology to gll2146 of G. violaceus of 44% (trembl|Q7NIN7(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein
YP_931855.1	Forms with NodI a membrane transport complex involved in the nodulation process. it probably exports a modified beta-1,4-linked n-acetylglucosamine oligosaccharide. Belongs to the ABC-2 integral membrane protein family, TREMBL:Q7WHD1 (49% identity); SWISSPROT:O52619 (49% identity). InterPro (IPR000412): ABC transporter family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting six transmembrane helices. TC (3.A.1.102): The Lipooligosaccharide Exporter (LOSE) Family.; High confidence in function and specificity
YP_931856.1	Conserved hypothetical protein. Homology to mvpT of E. carotovora of 44% (trembl:Q6D393) No domains predicted. No TMHs No signal peptide
YP_931857.1	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No signal peptide No TMHs
YP_931858.1	Region start changed from 377491 to 377176 (315 bases)
YP_931859.1	Conserved hypothetical protein. Homology to lpg1234 of L.pneumophila of 42% (gnl|keqq|lpn:lpg1234(KEGG)). Has PF04471, Restriction endonuclease;IPR007560, Mrr_cat; Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. No TMHs. No signal peptide.
YP_931860.1	Putative hypothetical very short patch repair endonuclease. Homology to vrs of E. coli of 29% (sprot|VSR_ECOLI) All proteins in this family for which functions are known are G:T mismatch endonucleases that function in a specialized mismatch repair process used usually to repair G:T mismatches in specific sections of the genome. Interpro: DNA mismatch endonuclease vsr (IPR004603) Pfam: DNA mismatch endonuclease Vsr Tigrfam: vsr: DNA mismatch endonuclease no signal peptide no TMHs; Family membership
YP_931862.1	Region start changed from 382943 to 383189 (246 bases)
YP_931863.1	Conserved hypothetical membrane protein. Homology to MS2110 of M.succiniciproducens of 40% (gi|52426165|ref|YP_089302.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Family membership
YP_931864.1	Nod factor export ATP-binding protein. Part of the ABC transporter complex nodIJ (TC 3.A.1.102.1) involved in the export of LCO (lipo-chitin oligosaccharide) and a modified beta-14-linked N- acetylglucosamine oligosaccharide. Responsible for energy coupling to the transport system, TREMBL:Q7W9D3 (58% identity); SWISSPROT:O52618 (53% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. Pfam (PF00005): ABC transporter. TC (3.A.1.102) The Lipooligosaccharide Exporter (LOSE) Family.; High confidence in function and specificity
YP_931865.1	Conserved hypothetical glutathione S-transferase. Homology to cv3306 of C. violaceum of 50% (trembl|Q7NSW3). Conjugation of reduced glutathione to a variety of targets. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain. no signal peptide. no TMHs; Conserved hypothetical protein
YP_931866.1	Conserved hypothetical protein. Homology to rsc0328 of R. solanacearum of 59% (trembl|Q8Y2K7). Pfam: Prolyl oligopeptidas family no signal peptide no TMHs
YP_931867.1	Putative ferredoxin 2fe-2s protein. Homology to fer2 of C. pasteruianum of 35% (sprot|FER2_CLOPA). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. no signal peptide no TMHs; Family membership
YP_931868.1	Conserved hypothtical membrane protein. Homology to rc03284 of R. solanacearum of 35% (trembl|Q8Y2L8(SRS) Has a weak hit to PF04892(IPR006976;vanZ)in Smart:This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin,showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors . no signal peptide 10 TMHs; Conserved hypothetical protein
YP_931869.1	Conserved Hypothetical protein, Q82Y48,Rhodanese type protein. Has SMART SM00450 Rhodanese Homology Domain(RHOD)starting at position 47-153aa;Rhodanese, a sulfurtransferase involved in cyanide detoxification (see IPR001307) shares evolutionary relationship with a large family of proteins. No Signal peptide or TMH reported Present.; Family membership
YP_931870.1	Probable serine O-acetyltransferase plasmid (EC 2.3.1.30) (SAT). Homology to srpH of Synechococcus of 55% (sprot|SRPH_SYNP7) no signal peptide no TMHs; High confidence in function and specificity
YP_931871.1	SgrAlc control protein,; High confidence in function and specificity
YP_931872.1	Probable immunodominant 35 kDa protein. Homology to mmpI of Mycobacterium avium of 69% (gi|2498566|sp|Q48899|MMP1_MYCAV(SwissProt (ExPASy)). No domains predicted. No signal peptide. No TMHs.,; High confidence in function and specificity
YP_931873.1	Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear
YP_931874.1	Conserved hypothetical membrane protein. Homology to NE2493 of Nitrosomonas europaea of 67% (trembl|Q82S65(SRS)). Has PF01169, Uncharacterized protein family UPF0016;IPR001727; This family contains integral membrane proteins of unknown function. Most members of the family contain two copies of a region that contains an EXGD motif. No signal peptide. 5 TMHs; Conserved hypothetical protein
YP_931875.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_931876.1	Entry name SWISSPROT:YHBT_ECOLI Prim. accession # P45474 InterPro IPR003033; SCP2. Pfam PF02036; SCP2; 1. Prediction: Non-secretory protein Signal peptide probability: 0.001 Number of predicted TMHs: 0 Identities = 46/107 (42%)
YP_931877.1	Conserved hypothetical peptidase. Homology to Rsp0969 of R. solanacearum of 51% (trembl|Q8XR90). Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership
YP_931878.1	Conserved hypothetical peptidase. Homology to cv4084 of C. violaceum of 64% (trembl|Q7NQQ39. Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership
YP_931879.1	TREMBL:Q8Y273: 59% identity, 72% similarity Osmoregulated proline transporter (Sodium/proline symporter). CATALYZES THE SODIUM-DEPENDENT UPTAKE OF EXTRACELLULAR PROLINE. InterPro: Sodium:solute symporter family InterPro:IPR001734; Na/solut_symport. Pfam:PF00474; SSF; TMHMM predicted transmembrane helices sss: SSS sodium solute transporter sup; Function unclear
YP_931880.1	Conserved hypothetical protein. Homology to ebA3609 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA3609(KEGG)). InterPro: Aminotransferase class-III (IPR005814), Arginase family (IPR00594). Pfam: Aminotransferase class-III,Arginase family. Tigrfam: argD: acetylornithine and succinylornithine aminotransferase, GABAtrnsam:4-aminobutyrate aminotransferase. no signal peptide. no TMHs
YP_931881.1	an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions
YP_931882.1	Putative TonB-dependent receptor. Homology to bpp0186 ao B. parapertussis of 54% (trembl|Q7W206) The TonB protein interacts with outer membrane receptor proteins that carry out high-affinity binding and energy-dependent uptake of specific substrates into the periplasmic space. These substrates are either poorly permeable through the porin channels or are encountered at very low concentrations. In the absence of TonB these receptors bind their substrates but do not carry out active transport. Interpro: TonB-dependent receptor (IPR000531) Pfam: TonB-dependent receptor (PF00593) signal Peptide no TMHs; Family membership
YP_931883.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide. No TMHs
YP_931884.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_931885.1	Conserved hypothetical secreted protein. Homology to CV3999 of C.violaceum of 34% (trembl|Q7NQY6(SRS)). Pfam: Sporulation related repeat This 35 residue repeat is found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This repeat might be involved in binding peptidoglycan (Bateman A pers obs). No TMHs. Signal peptide present; Conserved hypothetical protein
YP_931886.1	Putative protein disulfide-isomerase. Homology to dsbA of P. flourescens of 34%. Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins. Tigrfam: redox_disulf_1: redox-active disulfid Pfam: DSBA Oxidoreductase signal peptide no TMHS; Family membership
YP_931887.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8Y2Q1 (42% identity); SWISSPROT:P25970 (34% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_931888.1	Hypothetical protein. No Good homologs in the DB matching the length of the protein. No Significant domains,features,motifs present.
YP_931889.1	Hypothetical membrane protein. Homology to vng2292h of Halobacterium sp. of 25% (trembl|Q9HN16(SRS). no domains predicted .no signal peptide. 10 TMHs
YP_931890.1	Hypothetical membrane protein. No good homology to a protein of similar length in the data bank. no domains predicted no singal peptide 9 TMHs
YP_931891.1	Conserved hypothetical periplasmic binding proten. Homology to rs03250 of R. solanacearum of 53% (trembl|Q8Y2Q2). Interpro: Periplasmic binding protein (IPR002491). Pfam: Periplasmic binding protein (PF01497). This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport. no signal peptide. no TMHs.; Conserved hypothetical protein
YP_931892.1	Conserved hypothetical protein. Homology to ebA3626 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA3626(KEGG)). InterPro: Protein of unknown function DUF132 InterPro:IPR002850; DUF132. IPR002716; PIN. IPR006596; PINc. Pfam:PF01850; PIN; SMART:SM00670; PINc; TIGRFAMs:TIGR00305; DUF132 TIGR00305: conserved hypothetical protein T. Non-secretory protein with very low signalpeptide probability (0.003) (Signal P predicted). Absence of transmembrane helices
YP_931893.1	Function:-Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name TREMBL:Q8KXD5 Prim. accession # Q8KXD5 Identities = 354/607 (58%) InterPro IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Number of predicted TMHs: 0; High confidence in function and specificity
YP_931894.1	conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices.; Specificity unclear
YP_931895.1	Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif.; Family membership
YP_931896.1	Similar to TREMBL:Q8YBL0 (47% identity); TREMBL:Q987R7 (50% identity); TREMBL:Q7WA35 (55% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050.; Function unclear
YP_931897.1	Probable acyl-CoA thiolase. Homology to fadAx of P. putida of 67% (gnl|keqq|ppu:PP2215(KEGG)). IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC:2.3.1.9) and 3-ketoacyl-CoA thiolase (EC:2.3.1.16). 3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid -oxidation. Acetoacetyl-CoA thiolase (also called thiolase II) is specific for the thiolysis of acetoacetyl-CoA and involved in biosynthetic pathways such as poly -hydroxybutyrate synthesis or steroid biogenesis.Prediction: Non-secretory protein Signal peptide probability: 0.002 Number of predicted TMHs: 0; Specificity unclear
YP_931898.1	Activity:- Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name TREMBL:Q9AHX9 Prim. accession # Q9AHX9 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Identities = 244/375 (65%) Number of predicted TMHs: 0; Family membership
YP_931899.1	Similar to TREMBL:Q8Y2R2 (42% identity); TREMBL:Q7WEK4 (30% identity); TREMBL:Q88IW7 (27% identity). Pfam (HCCA_isomerase): 2-hydroxychromene-2-carboxylate isomerase.; Family membership
YP_931900.1	Conserved hypothetical protein. Homology to cc1308 of C. crescentus of 35% (trembl|Q9A8P5). Pfam:DUF1289 This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown. no signal peptide no TMHs
YP_931901.1	Hypothetical protein, 54% identity to TrEMBl;Q8YGQ7. Has PF06945, Protein of unknown function (DUF1289);IPR010710;This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown.
YP_931902.1	Probable Hypothetical protein ycbL. TREMBL:Q8Y2S7-43% identity,57% similarity. TIGRFAM:2A0115-Benzoate transport proteins belong to this group. Benzyl alcohol,benzaldehyde, benzoate, and anthranilate are metabolized via catechol, cis,cis-muconate, and the beta-ketoadipate pathway in some bacteria InterPro: Metallo-beta-lactamase superfamily Pfam:Metallo Beta lactamase superfamily, Phage lysozyme TMHMM predicted transmembrane heleces ftsZ: cell division protein FtsZ; Function unclear
YP_931903.1	Hypothetical UPF0042 protein YPO3586/Y0158. SWISPROT:Q82TN5: 6i% identity, 78% similarity This is a family of putative P-loop ATPases. Many of the proteins in this family are hypothetical and kinase activity has been proposed for some family members InterPro:IPR005337; UPF0042. Pfam: PF03668; ATP_bind_2 No Signal peptide (Signal P predicted) No transmembrane helices (TMHMM predicted) cmk: cytidylate kinase; Function unclear
YP_931904.1	Conserved hypothetical membrane protein. Homology to TP1032 of Treponema pallidum of 32% (sprot|YA32_TREPA(SRS)). Has PF07009(IPR010739):Protein of unknown function (DUF1312);This family consists of several bacterial proteins of around 120 residues in length. The function of this family is unknown. No singal peptide. 1 TMH; Conserved hypothetical protein
YP_931905.1	Heptaprenyl diphosphate synthase component I, 23% identity (45% similarity) to TrEMBL;Q896H9. Has PF07456,Heptaprenyl diphosphate synthase component I;IPR010898,Hpre_diP_synt_I: This family contains component I of bacterial heptaprenyl diphosphate synthase (approximately 170 residues long). This is one of the two dissociable subunits that form the enzyme, both of which are required for the catalysis of the biosynthesis of the side chain of menaquinone-7.
YP_931906.1	regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins
YP_931907.1	Probable chemotaxis protein methyltransferase,CheR_Metranf. IPR001601; Methyltransf. IPR000051; SAM_bind. Pfam: PF01739; CheR. PF03705; CheR_N. SMART: SM00138; MeTrc. Chemotaxis protein methyltransferase (EC 2.1.1.80). METHYLATION OF THE MEMBRANE-BOUND METHYL-ACCEPTING CHEMOTAXIS PROTEINS (MCP) TO FORM GAMMA-GLUTAMYL METHYL ESTER RESIDUES IN MCP.Annotation derived from meta auto annotator.; High confidence in function and specificity
YP_931908.1	Conserved hypothetical chemotaxis protein CheD. Homology to cheD of S. oneidensis of 41% (trembl|Q8EF62). Interpro: CheD (IPR005659). Pfam: CheD (PF03975). This chemotaxis protein stimulates methylation of MCP proteins. no signal peptide. no TMHs; Conserved hypothetical protein
YP_931909.1	Probable positive regulator of CheA protein activity, CheW. Pfam: PF01584; CheW. SMART: SM00260; CheW. Chemotaxis protein cheW.Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges chea to the mcps (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to cheY and cheB.; High confidence in function and specificity
YP_931910.1	Methyl-accepting chemotaxis protein, only very low similarity to SWISSPROT: sprot|Y4FA_RHISN (14% Rhizobium sp. (strain NGR234). InterPro: IPR004090; Me_chemotaxis. IPR004089; Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Family membership
YP_931911.1	Methyl-accepting chemotaxis protein, only very low similarity to SWISSPROT: sprot|Y4FA_RHISN (14% Rhizobium sp. (strain NGR234). InterPro: IPR004090; Me_chemotaxis. IPR004089; Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices.; Family membership
YP_931912.1	Putative chemotaxis histidine kinase protein,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. Chemotaxis protein cheA (EC 2.7.3.-). INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY.; High confidence in function and specificity
YP_931913.1	Putative anti-sigma factor antagonists (STAS domain protein), STAS. Pfam: PF01740; STAS. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.; Function unclear
YP_931914.1	Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. Pfam: PF00015; MCPsignal. SMART: SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Function unclear
YP_931915.1	Probable chemotaxis response regulator,; High confidence in function and specificity
YP_931916.1	Conserved hypothetical membrane protein. Homology to rsc0739 of R. solanacearum of 52% (trembl|Q8Y1F1). Pfam: DUF395 This family includes YeeE and YedE from E. coli. These proteins are integral membrane proteins of unknown function. Many of these proteins contain two homologous regions that are represented by this family. This region contains several conserved glycines and an invariant cysteine that is probably an important functional residue. signal peptide 8 TMHs; Conserved hypothetical protein
YP_931917.1	Conserved hypothetical ExsB protein. Homology to exsB of P. syringae of 70% (trembl|Q87Y44). This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In Rhizobium meliloti, a species in which the exo genes make succinoglycan, a symbiotically important exopolysaccharide, exsB is located nearby and affects succinoglycan levels, probably through polar effects on exsA expression or the same polycistronic mRNA. Interpro: ExsB (IPR004479). Pfam: ExsB (PF06508). Tigrfam: TIGR00364: exsB protein. Has signal peptide present. No TMHs; Family membership
YP_931918.1	Conserved hypothetical radical activating enzyme. Homology to xac3139 of X. axonopodis of 60% (trembl|Q8PHW0). InterPro: Radical activating enzymes (IPR001989) Pfam: Radical activating enzyme no signal peptide no TMHs; Family membership
YP_931919.1	Conserved hypothetical secreted protein. Homology to RS05116 of R.solanacearum of 38% (trembl|Q8Y1F3(SRS)) No domains predicted. No TMHs Has signal peptide.; Conserved hypothetical protein
YP_931920.1	Putative peptidoglycan-associated lipoprotein. Homology to pal of E. coli of 36% (sprot|PAL_ECOLI). Thought to play a role in bacterial envelope integrity. Very strongly associated with the peptidoglycan. Pfam: ompA family signal peptide no TMHs; Family membership
YP_931921.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_931922.1	Conserved hypothetical membrane protein. Homology to tolA of N. europaea of 39% (trembl|Q82XP0). no domains predicted InterPro: Proline-rich region (IPR000694) no signal peptide 1 TMHs; Conserved hypothetical protein
YP_931923.1	Putative translocation protein TolR. Holomology to tolR of P. aeruginosa of 30% (sprot|TOLR_PSEAE) Involved in eth TonB-independent uptake of proteins. no signal peptide probable 1 TMH; Family membership
YP_931924.1	Translocation protein TolQ. Homology to tolQ of R. solanacearum of 52%. Involved in the tonB-independent uptake of proteins. InterPro: MotA/TolQ/ExbB proton channel family Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHs; High confidence in function and specificity
YP_931925.1	Conserved hypothetical thioesterase. Homology to bb4233 of B. bronchiseptica of 41% (trembl|Q7WFN8). Tigrfam: TIGR00051: conserved hypothetical protein .Pfam: 4-hydroxybenzol-CoA thioesterase (PF0361). Interpro: 4-hydroxybenzol-CoA thioesterase (IPR006684); thioesterase superfamily (IPR006683) This family contains a wide variety of enzymes, principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3. This family includes various cytosolic long-chain acyl-CoA thioester hydrolases. Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. no signal peptide. no TMHs; Family membership
YP_931926.1	SPROT:P37718: 26% identity, 43% similarity Cellulose synthase operon protein C precursor. Required for maximal bacterial cellulose synthesis. InterPro: STAS domain. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. InterPro:IPR008410; BCSC_C. IPR003921; Cell_synth_C. Pfam:PF05420; BCSC_C; 1. ant_ant_sig: anti-anti-sigma factor No signal peptide present SignalP predicted). No transmembrane helices present (TMHMM predicted); Function unclear
YP_931927.1	heat shock protein involved in degradation of misfolded proteins
YP_931928.1	heat shock protein involved in degradation of misfolded proteins
YP_931929.1	Putative malonate transporter. subcellular location:integral membrane protein (potential). similarity: belongs to the auxin efflux carrier (tc 2.a.69) family. SPROT:P56948:24% identity, 41% similarity. InterPro: IPR004776; Auxin_eff. Pfam:PF03547; Auxin_eff 2a69: Auxin Efflux Carrier; Specificity unclear
YP_931930.1	GGDEF/PAS-domain containing protein
YP_931931.1	Heat shock protein 15 homolog (HSP15). INVOLVED IN THE RECYCLING OF FREE 50S RIBOSOMAL SUBUNITS THAT STILL CARRY A NASCENT CHAIN. BINDS RNA MORE SPECIFICALLY THAN DNA. BINDS WITH VERY HIGH AFFINITY TO THE FREE 50S RIBOSOMAL SUBUNIT. DOES NOT BIND IT WHEN IT IS PART OF THE 70S RIBOSOME; Conserved hypothetical protein
YP_931932.1	55% Adenylylsulfate kinase (EC 2.7.1.25) (APS kinase) (ATP adenosine-5-phosphosulfate 3-phosphotransferase)], from Pseudomonas aeruginosa. FUNCTION:ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity (By similarity). FUNCTION:APS kinase catalyzes the synthesis of activated sulfate (By similarity). CATALYTIC ACTIVITY:ATP + sulfate = diphosphate + adenylylsulfate. CATALYTIC ACTIVITY:ATP + adenylylsulfate=ADP +3'-phosphoadenylylsulfate. PATHWAY: Sulfate activation; cysteine biosynthesis reductive branch; first step. PATHWAY:Sulfate activation; cysteine biosynthesis reductive branch; second step. SUBUNIT:Heterodimer composed of cysD, the smaller subunit,and cysN (By similarity). SIMILARITY:In the N-terminal section; belongs to the GTP-binding elongation factor family. CysN/nodQ subfamily. SIMILARITY:In the C-terminal section; Belongs to the APS kinase family. SWISSPROT:CYSN_PSEAE:O50274. InterPro:IPR002891;APS_kinase.IPR004161;EFTU_D2.IPR009001; Elong_init_C.IPR000795; ProtSyn_GTPbind.IPR005225; Small_GTP.IPR009000; Translat_factor. Pfam:PF01583; APS_kinase; 1.PF00009; GTP_EFTU; 1.PF03144; GTP_EFTU_D2;1. TIGRFAMs:TIGR00455; apsK; 1.TIGR00231; small_GTP; 1.; High confidence in function and specificity
YP_931933.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_931934.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
YP_931935.1	Conserved hypothetical protein. Homology to PA1837 of P.aeruginosa of 50% (tremble:Q9I2Q8). Has PF06073,Bacterial protein of unknown function (DUF934);IPR008318 UCP030820: This family consists of several bacterial proteins of unknown function. One of the members of this family Q8YEW3 is thought to be an oxidoreductase. No signal peptide. No TMHs
YP_931936.1	49% Fd-NiR.IPR011255; NiR_SiRalpha_1/3.IPR006067; Nir_Sir_4Fe4S.IPR005117; NiR_SiR_beta_fer. Pfam:PF01077; NIR_SIR; 2.PF03460; NIR_SIR_ferr; 2.; High confidence in function and specificity
YP_931937.1	Conserved hypothetical membrane protein. Homology to bll1489 of B. japonicum of 58% (trembl|Q89UC8(SRS)) InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81 Presence of 8 transmembrane helices (TMHMM predicted) probable transmembrane protein of unknown function) no signal peptide; Conserved hypothetical protein
YP_931938.1	HTH-type transcriptional regulator cysB (Cys regulon transcriptional activator). this protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of l-cysteine from inorganic sulfate. the inducer for cysb is n-acetylserine. cysb inhibits its own transcription.; High confidence in function and specificity
YP_931939.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal peptide present. No TMHs
YP_931940.1	L-asparaginase precursor (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase).; Family membership
YP_931941.1	Region start changed from 463959 to 463827 (-132 bases)
YP_931942.1	L-asparaginase precursor (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase).; High confidence in function and specificity
YP_931943.1	Glutamine transport ATP-binding protein glnQ. Homology with glnQ of B. stearothermophilus of 56% (sprot|GLNQ_BACST). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. InterPro: AAA ATPase superfamily (IPR003593), ABC_transporter (IPR003439), ATP/GTP_binding site motif A (P-loop) (IPR001687) Pfam: ABC transporter no signal peptide no TMHs; High confidence in function and specificity
YP_931944.1	Putative glutamine transport permease. Homology to glnM of B. subtilis of 30% (TREMBL:O34671) Probably part of the binding-protein-dependent transport system of amino acids. Probably responsible for the translocation of the substrate across the membrane InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component no signal peptide probable 5 TMHs; Family membership
YP_931945.1	Glutamate/aspartate transport system permease gltJ. Homology to glnP of B. subtilis of 23% (CAA93320). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR AMINO ACID; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component HTH-motif probable 4 TMHs no signal peptide; Family membership
YP_931946.1	Putative glutamine-binding protein. Homology to glnH of B. stearothermophilus of 28% (sprot|GLNH_BACST). Involved in glutamine-transport system. Interacts with the glutamine-transport system glnPQM. Pfam: Bacterial extracellular solute binding protein no TMHs signal peptide; Family membership
YP_931947.1	Conserved Hypothetical protein(Metallo-beta-lactamase superfamily). Has PF00753, Metallo-beta-lactamase superfamily; IPR001279, Blactmase-like;These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. Except for the competence protein these proteins bind two zinc ions per molecule as cofactor.; Family membership
YP_931948.1	catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA
YP_931949.1	Putative ATP-dependent helicase MTH1802. TREMBL:Q88NV1: 57% identity, 66% similarity InterPro:IPR001410; DEAD/DEAH box helicase IPR001650; Helicase_C. Pfam: PF00270; DEAD; 1. PF00271; Helicase_C; 1. SMART: SM00487; DEXDc; 1. SM00490: HELICc livcs: branched-chain amino acid trans Non secretory protein with low probablity of cleavage site (0.167): Signal P predicted. No transmembrane helices (TMHMM predicted); High confidence in function and specificity
YP_931950.1	Probable Hypothetical protein MJ0037. Members of this uncharacterized family share a motif approximating DXH(X25)GDXXD(X25)GNHD as found in several phosphoesterases, including the nucleases SbcD and Mre11. SbcD is a subunit of the SbcCD nuclease of Escherichia coli that can cleave DNA hairpins to unblock stalled DNA replication. All members of this family are archaeal TREMBL:Q88NV2: 46% identity, 59% similarity InterPro:IPR004843; M-ppestrase. Pfam: PF00149; Metallophos; No transmembrane helices TIGR00024: conserved hypothetical prot; Function unclear
YP_931951.1	C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity
YP_931952.1	C4-dicarboxylate transport sensor protein,; High confidence in function and specificity
YP_931953.1	Glutathione-regulated potassium-efflux system protein kefB,(K+/H+ antiporter).Transport system that facilitates potassium-efflux possibly by potassium-proton antiport. 32% K_eff.IPR006153; Na_H_porter.IPR006036;TrkA_Kuptake. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA-N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix:12. Belongs to the monovalent cation:proton antiporter 2 (cpa2) transporter (TC 2.A.37) family. KefB subfamily.; High confidence in function and specificity
YP_931954.1	PAS/PAC/GGDEF-domain containing protein,implicating involvement into signalling processes. Similarity to TREMBL: trembl|Q98JA6 (30% Rhizobium loti,hypothetical protein mlr2027) InterPro: IPR000160 GGDEF. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. Pfam: PF00990 GGDEF. SMART: SM00086 PAC. SM00091 PAS. TIGRFAM: TIGR00254 GGDEF. TIGR00229 sensory_box.
YP_931955.1	Hypothetical secreted protein. No homology with hits in the Database. No domains predicted. Signal peptide present. No TMHs
YP_931956.1	Putative thioredoxin reductase. Homology to trxB of S. coelicolor of 25% (sprot|TRXB_STRCO). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership
YP_931957.1	Probable composite transport ATP-binding permease protein. Homology to amt1 of S. cereviciae of 48% (sprot|ATM1_YEAST). COULD BE INVOLVED IN THE TRANSPORT OF yet unknow substrates (probable HEME) FROM THE MITOCHONDRIA TO THE CYTOSOL. InterPro: ABC transporter transmembrane region (IPR001140), ATP/GTP-binding site motif A (P loop) (IPR001687), ABC transporter (IPR003439),AAA_ATPase sperfamily (IPR003593) Pfam: ATP transporterABC transporter transmembrane region no signal peptide probable 6 TMHs; Specificity unclear
YP_931958.1	Conserved hypothetical threonine efflux protein. Homology to rsc0148 of R. solanaxearum of 52% (trembl|Q8Y2B8). InterPro: Lysine exporter protein (LYSE/YGGA) (IPR001123) Pfam: LysE type translocator Tigrfam: 2A76: Homoserine/Threonine efflux protein signal peptide Probable 6 TMHs; Family membership
YP_931959.1	This family of proteins contains P47K, a Pseudomonas chlororaphis protein needed for nitrile hydratase expression, and the cobW gene product, which may be involved in cobalamin biosynthesis in Pseudomonas denitrificans [1]. TREMBL:Q8YJP6: 40% identity, 54% similarity. Pfam:PF02492; Cobalmine synthesis protein; pfkB family carbohydrate kinase; FAD binding domain. TIGRFAM:proC: pyrroline 5 carboxylate reductase. mobB: molybdopterin-guanine dinucleotide; Family membership
YP_931960.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide. no TMHs
YP_931961.1	Response regulator,; High confidence in function and specificity
YP_931962.1	Putative sensor kinase,; High confidence in function and specificity
YP_931963.1	Putative ammonium transporter MJ1343. A number of evolutionarily-related proteins have been found to be involved in the transport of ammonium ions across membranes.Represent a family of high affinity ammonium transporters. These proteins are highly hydrophobic and seem to contain from 10 to 12 transmembrane domain. TREMBL:Q88L29: 73% identity, 84% similarity InterPro: Ammonium transporter family InterPro: IPR001905; Ammonium_transpt. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp; 1. PROSITE: PS01219; AMMONIUM_TRANSP amt: ammonium transporter Non secretory protein with signal peptide probability of 0.174 (SignalP predicted) TMHMM predicted 11 TMH's; High confidence in function and specificity
YP_931964.1	Putative Dnr-like transcriptional activator. Similar to SWISSPROT: sprot|FIXK_RHIME (28% Rhizobium meliloti, FixK) InterPro: IPR000595 cNMP_binding. IPR001808 HTH_Crp. Pfam: PF00027 cNMP_binding. HTH reporting nucleic acid binding motif.; Family membership
YP_931965.1	Hypthetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Has signal peptide.
YP_931966.1	Conserved hypothetical secreted protein. Homology to an orf of Trichodesmium erythraeum of 45% (gi|48892210|ref|ZP_00325608.1|(NBCI ENTREZ)). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_931967.1	functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA
YP_931968.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_931969.1	alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1.; Family membership
YP_931970.1	Conserved hypothetical acyl-CoA thioesterase. Homology to an orf of Azoarcus sp. EbN1 (trembl|Q8G9D6). Pfam: cytosolic long-chain acyl-CoA thioesterase Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. Interpro: Thioesterase superfamily (IPR006683) no signal peptide no. TMHs; Family membership
YP_931971.1	Long-chain fatty acid transport protein precursor (Outer membrane fadL protein) (Outer membrane flp protein). Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel (By similarity). Entry name:- Q8G9D7 Primary accession number:- Q8G9D7 InterPro:- IPR005017; Toluene_X. Pfam:- PF03349; Toluene_X; 1. identity:- 66% Prediction: Signal peptide Signal peptide probability: 1.0 Number of predicted TMHs: 0; High confidence in function and specificity
YP_931972.1	Short-chain enoyl-CoA hydratase activity . Activity:- 3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name TREMBL:Q8P986 Prim. accession # Q8P986 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1. Identities = 468/796 (58%) Prediction: Signal peptide Signal peptide probability: 0.980 Number of predicted TMHs: 0; Family membership
YP_931973.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_931974.1	Function:- COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). CATALYTIC ACTIVITY:-(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O. Entry name SWISSPROT:PAAG_ECOLI Prim. accession # P77467 InterPro:- IPR001753; EnCoA_hydrtse. Pfam:-PF00378; ECH; 1. Identities = 92/265 (34%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_931975.1	Conserved hypothetical membrane protein. Homology to cv1508 of C. violaceum of 37% (trembl|Q7NXW8). Pfam: uncharacterized ACR, COG1434. no signal peptide. 2 TMHs; Conserved hypothetical protein
YP_931976.1	Probable O-acetylhomoserine aminocarboxypropyltransferase. Homology to cysD of A. nidulans of 54% (sprot|CYSD_EMENI). Transforms O-acetylhomoserine into homocysteine. InterPro: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes (IPR000277) Pfam: Cys/Met metabolism PLP-dependent enzymes no signal peptide no TMHs; High confidence in function and specificity
YP_931977.1	Hypothetical membrane protein. No good homology to the data bank. No domains predicted. 1 TMHs No signal peptide present.
YP_931978.1	Exported protein with sporulation related repeat. Pfam: Sporulation related repeat. InterPro: Proline-rich region; Function unclear
YP_931979.1	binds to flagellin and appears to stabilize flagellin during flagella assembly
YP_931980.1	Conserved hypothetical endoribonuclase L-PSP. Homology to orf1 of A. vineladii of 74% (sprot|YVN1_AZOVI(SRS)) This protein was described initially as an inhibitor of protein synthesis intiation but is now viewed as an endoribonuclease active on single-stranded mRNA. The cleavage of mRNA is responsible for the inhibition of protein synthesis. A role in purine regulation has also been suggested. Tigrfam: Endoribonuclease L-PSP, putative Pfam: Endoribonuclease L-PSP (=YipgF family) no TMHs weak indication for signal peptide; Conserved hypothetical protein
YP_931981.1	catalyzes branch migration in Holliday junction intermediates
YP_931982.1	Chorismate:pyruvate lyase (EC 4.-.-.-). catalytic activity: chorismate = 4-hydroxybenzoate + pyruvate. pathway: ubiquinone biosynthesis; first step.; Specificity unclear
YP_931983.1	catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway
YP_931984.1	Conserved hypothetical irons-sulfur binding oxidase. Homology to cv4235 of C. violaceum of 70% (trembl|Q7NQA5) Pfam: FAD binding domain; FAD linked oxidase, Cterminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership
YP_931986.1	Conserved hypothetical membrane protein. Homology to yqaA of Nitrosomonas europaea of 50% (trembl|Q82TH7(SRS)) No domains predicted. Signal peptide present. TMHMM2 reporting presence of 2 TMH's.; Conserved hypothetical protein
YP_931987.1	Conserved hypothetical secreted protein. Homology to PA4874 of P.aeruginosa of 36% (trembl|Q9HUT9(SRS)) No domains predicted. Signal petide present. No TMH present.; Conserved hypothetical protein
YP_931988.1	FHA domain containing protein. Best similarity to SWISSPROT: sprot|REPB_AGRRH (9% Agrobacterium rhizogenes,possible replication protein b) Pfam: PF00211 Adenylate and Guanylate cyclase catalytic domain. SMART: SM00240 FHA Forkhead associated domain.
YP_931989.1	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs
YP_931990.1	Involved in pteridine salvage and antifolate resistance
YP_931991.1	Conserved hypothetical protein. Homology to NE1166 of N.europaea of 49% (tremble:Q82VC8) Has PF02636,Uncharacterized ACR, COG1565;IPR003788 ,DUF185; This family contains several uncharacterised proteins. Q8YI87 has been described as an ATP synthase beta subunit transcription termination factor rho protein. No signal peptide. No TMHs.
YP_931992.1	Conserved hypothetical protein. Homology to ebA3372 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA3372(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_931993.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_931994.1	TREMBL:Q8F3A6: 43% identity, 60% similarity Non-heme chloroperoxidase (EC 1.11.1.10) (Chloride peroxidase) (CPO-P) (Chloroperoxidase P). CHLORINATES AND BROMINATES SUITABLE ORGANIC COMPOUNDS. INVOLVED IN THE BIOSYNTHESIS OF THE ANTIBIOTIC PYRROLNITRIN. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR003089: AB_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1; 1 TIGRFAM:dsbE: periplasmic protein thiol:disulf; Family membership
YP_931995.1	Probable glutathione S-transferase. Homology to isoJ of Rhodococcus sp AD45 of 48% (trembl|Q9RBP3). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity
YP_931996.1	Conserved hypothetical membrane protein. Homology to BH1226 of Bacillus halodurans of 40% (pir|B83803) no domains predicted. signal peptide. 1 TMHs; Conserved hypothetical protein
YP_931997.1	catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
YP_931998.1	Putative stringent starvation protein A. Homology to sspA of E. coli of 26% (sprot|SSPA_ECOLI). FORMS AN EQUIMOLAR COMPLEX WITH THE RNA POLYMERASE HOLOENZYME (RNAP) BUT NOT WITH THE CORE ENZYME. IT IS SYNTHESIZED PREDOMINANTLY WHEN CELLS ARE EXPOSED TO AMINO ACID STARVATION AT WHICH TIME IT ACCOUNTS FOR OVER 50% OF THE TOTAL PROTEIN SYNTHESIZED. InterPro: Glutathione S-transferase N terminus (IPR001045) Pfam: Glutathione S-transferase, N-terminal domaine no signal peptide no TMHs; Family membership
YP_931999.1	33%; Specificity unclear
YP_932000.1	Putative soluble lytic murein transglycosylase. Homology to slt of E. coli of 24% (sprot|SLT_ECOLI). Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. InterPro: SLT domain (IPR000189) Pfam: Transglycosylase SLT domain singal peptide no TMHs; High confidence in function and specificity
YP_932001.1	5-formyltetrahydrofolate cyclo-ligase InterPro: 5-formyltetrahydrofolate cyclo-ligase; Specificity unclear
YP_932002.1	GGDEF/PAS/PAC-domain containing protein. Similarity to SWISSPROT: sprot|Y4LL_RHISN (13% Rhizobium sp. (strain NGR234), hypothetical 91.8 kda protein y4ll) / TREMBL: trembl|Q55955 (14% Synechocystis sp. (strain PCC 6803),sll0779) Pfam: PF00990 GGDEF domain. PF00989 PAS. PF00785 PAC. TIGRFAM: TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box. TMHMM reporting 2 transmembrane helices.
YP_932003.1	Putative cyclohexadienyl dehydratase precursor. Homology to pheC of P. aeruginosa of 36% (sprot|PHEC_PSEAE) FORMS ALTERNATIVE PATHWAY FOR PHENYLALANINE BIOSYNTHESIS. CAN CATALYZE TWO REACTIONS: PREPHENATE DEHYDRATASE AND AROGENATE DEHYDRATASE. MAY HAVE A ROLE IN CHEMOTAXIS OR TRANSPORT. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638), solute-binding protein/glutamate receptor (IPR001311) Pfam: Bacterial extracellular solute-binding proteins signal peptide no TMHs; Function unclear
YP_932004.1	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway
YP_932005.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
YP_932006.1	Probable nitrogen regulatory IIA protein,; High confidence in function and specificity
YP_932007.1	Probable sigma 54 modulation protein,; High confidence in function and specificity
YP_932008.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_932009.1	Probable ABC transporter ATP-binding protein HI1148. ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. TREMBL:Q7NST9: 64% identity,75% similarity InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. IPR000767; Disease_resist. IPR003016; Lipoyl_BS. Pfam PF00005; ABC_tran; 1 mobB: molybdopterin-guanine dinucleoti TMH's present 0; High confidence in function and specificity
YP_932010.1	Regulatory protein recX. Modulates recA activity (By similarity). TREMBL: Q7WKM9: 45% identity, 63% similarity InterPro: RecX regulatory protein InterPro; IPR003783; RecX. Pfam: PF02631; RecX PPR: pentatricopeptide repeat domain No transmembrane helices present; Family membership
YP_932011.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_932012.1	Hypothetical 17.2 kDa protein 1 in recA 5region. TREMBL:Q9KUH9: 54% identity, 64% similarity CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation [1]. This is a C-terminal region of putative competence-damaged proteins from the cin operon InterPro:IPR008136; CinA_C. Pfam: PF02464; CinA cinA_cterm: competence/damage-inducible p No signal peptide. No transmembrane helices; High confidence in function and specificity
YP_932013.1	Region start changed from 546007 to 546100 (93 bases)
YP_932014.1	Thiamine-phosphate kinase. catalytic activity: atp + thiamine phosphate = adp + thiamine diphosphate. pathway: thiamine biosynthesis.; High confidence in function and specificity
YP_932016.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
YP_932017.1	Probable electron transport complex protein rnfG. Homolog to rnfG of R. capsulata of 51% (sprot|RNFG_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. signal peptide no TMHs; High confidence in function and specificity
YP_932018.1	Probable electron transport complex protein rnfD. Homology to rnfD of R. capsulatus of 42% (sprot|RNFD_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity). InterPro: NQR2 and RnfD/E related proteins (IPR004338) Pfam: NQR2, RnfD, RnfE family no signal peptide probable 7 TMHs; High confidence in function and specificity
YP_932019.1	Probable electron transport complex protein RnfC. Homology to rnfC of R. capsulatus of 48% (sprot|RNFC_RHOCA) Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Stabilizes rnfB. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit (IPR001949); 4Fe-4S ferredoxin, iron-sulfur bidning domain (IPR001450) Pfam: Respiratory-chain NADH dehydrogenase; 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_932020.1	Probable electron transport complex protein rnfB. Homology to rnfB of R. capsulatus of 48% (sprot|RNFB_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Stabilizes rnfC. Pfam: 4Fe-4S binding domain signal peptide no TMHs; High confidence in function and specificity
YP_932021.1	Probable electron transport complex protein RnfA. Homology to rnfA of R. capsultatus of 66% (RNFA_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Required for stable existence of rnfB and rnfC. InterPro: RnfA-Nqr electron transport subunit (IPR003667) Pfam: Rnf-Nqr subunit, membrane protein no signal peptide 6 TMHs; High confidence in function and specificity
YP_932022.1	Nitrogen fixation regulatory protein (EC 2.7.3.-). Required for the inhibition of nifA activity in response to oxygen and low level of fixed nitrogen. Similar to SWISSPROT: sprot|NIFL_AZOVI (41% Azotobacter vinelandii,nitrogen fixation regulatory protein (EC 2.7.3.-), NifL) InterPro: IPR003661 His_kinA_N. The histidine kinase A (phosphoacceptor) N-terminal domain is a dimerisation and phosphoacceptor domain of histidine kinases. It has been found in bacterial sensor protein/histidine kinases. IPR000014 PAS. PAS domains are involved in many signalling proteins where they are used as a signal sensor domain. IPR000700 PAS-assoc_C. IPR004358 Bact_sens_pr_C. IPR003594 ATPbind_ATPase. Pfam: PF00512 HisKA. PF00989 PAS. PF00785 PAC. TIGRFAM: TIGR00229 PAS domain S-box.; High confidence in function and specificity
YP_932023.1	Nif-specific regulatory protein. NIFA A TRANSCRIPTIONAL ACTIVATOR IS REQUIRED FOR ACTIVATION OF MOST NIF OPERONS WHICH ARE DIRECTLY INVOLVED IN NITROGEN FIXATION. NIFA INTERACTS WITH SIGMA-54. InterPro: Sigma-54 factor interaction domain; High confidence in function and specificity
YP_932024.1	Conserved hypothetical secreted protein. Homology to Gmet02000900 of Geobacter metallireducens of 45% (gi|48846570|ref|ZP_00300831.1|(NBCI ENTREZ)). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_932025.1	Hypothetical secreted protein. No Hits in the PDB. No domains predicted. No TMHs. Signal peptide present.
YP_932026.1	Superoxide dismutase [Cu-Zn]precursor (EC 1.15.1.1), sodC.Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May function against extracytoplasmic toxic oxygen species. 45% SOD_CU_ZN.Copper/Zinc superoxide dismutase. Pfam: PF00080; sodcu; 1. TIGR:CC1579. Signal peptide: present.; High confidence in function and specificity
YP_932027.1	FeMo cofactor biosynthesis protein nifB. PROBABLY INVOLVED IN THE SYNTHESIS OF THE FE-MO COFACTOR.; High confidence in function and specificity
YP_932028.1	Conserved hypothetical ferredoxin. Homology to fdx of P. stuzeri of 57% (trembl|Q93JV5). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4FE-4S binding domain no signal peptide no TMHs; Family membership
YP_932029.1	Conserved hypothetical protein. Homology to an orf of P. stuzeri of 49% (trembl|Q93JV4). Tigrfam: arsC: arsenate reductase. Pfam: ArsC family (PF03960) no signal peptide. no TMHs
YP_932030.1	Probable type A flavoprotein fprA . Homology to frpA of R. capsulatus of 58% (sprot|FPRA_RHOCA) Low-potential electron donor to a number of redox enzymes (Potential). InterPro: Metallo-beta-lactamase superfamily (IPR001279); Flavodoxin (IPR001226) Pfam: Metallo-beta-lactamase superfamily; Flavodoxin no singal peptide no TMHs; Family membership
YP_932031.1	Ferredoxin IV (FdIV) (Ferredoxin plant-type). Homology to fdxC of R. capsulatus of 62% (FER4_RHOCA). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN PROBABLY PARTICIPATES IN NITROGEN FIXATION. Pfam: 2Fe-2S iron-sulfur clauster binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_932032.1	Ferredoxin V (FdV) (Ferredoxin plant-type). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN PROBABLY PARTICIPATES IN NITROGEN FIXATION. InterPro: Ferredoxin; High confidence in function and specificity
YP_932033.1	Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership
YP_932034.1	Probable ADP-ribosyl-[dinitrogen reductase] hydrolase. Homology to draG of R. rubrum of 44% (sprot|DRAG_RHORU) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase (DraT) transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG). Pfam: ADP-ribosylglycohydrolase no signal peptide no TMHs
YP_932035.1	Conserved hypothetical secreted protein. Homology to PA2778 of P.aeruginosa of 39% (trembl|Q9I065(SRS)) Has Signal Peptide. No TMH present. Has PF03412:Peptidase C39 family;Lantibiotic and non-lantibiotic bacteriocins are synthesised as precursor peptides containing N-terminal extensions (leader peptides) which are cleaved off during maturation. Most non-lantibiotics and also some lantibiotics have leader peptides of the so-called double-glycine type. These leader peptides share consensus sequences and also a common processing site with two conserved glycine residues in positions -1 and -2. The double- glycine-type leader peptides are unrelated to the N-terminal signal sequences which direct proteins across the cytoplasmic membrane via the sec pathway. Their processing sites are also different from typical signal peptidase cleavage sites, suggesting that a different processing enzyme is involved. Peptide bacteriocins are exported across the cytoplasmic membrane by a dedicated ATP-binding cassette (ABC) transporter. The ABC transporter is the maturation protease and its proteolytic domain resides in the N-terminal part of the protein. This peptidase domain is found in a wide range of ABC transporters, however the presumed catalytic cysteine and histidine are not conserved in all members of this family.; Conserved hypothetical protein
YP_932036.1	Hypothetical membrane protein. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. 1 TMH
YP_932037.1	Hypothetical protein yjdF,44% identity (56% similarity) to TrEMBL;Q8XDT2. SwissProt;P39270. Signal P reporting Signal peptide present. TMHMM2 reporting 3 TMH's present.
YP_932038.1	Hypothetical membrane protein. TREMBL:Q83LX6: 27% identity, 42% similarity. similarity to E.coli ybeT. some,to yeast skt5 and s.pombe spac24b11.10c InterPro; IPR006597; Sel_like. InterPro; IPR001440; TPR. InterPro; IPR008941; TPR-like Pfam:DsbD:Cytochrome C biogenesis protein trans SMART:SM00671; SEL1 Signal peptide present (Signal P) transmembrane helices: 5 (TMHMM predicted).; Function unclear
YP_932039.1	DcrH: hemerythrin protein,is a transmembrane methyl-accepting protein probably involved in bacterial chemotaxis. 36% Hemerythrin. Hemerythrin family non-heme Pfam:PF01814; Hemerythrin; 1.; High confidence in function and specificity
YP_932040.1	Conserved hypothetical protein. Homology to an orf of Pseudomonas stutzeri of 52% (tremble:Q9EVM9). No domains predicted. No TMHs. No signal peptide.
YP_932041.1	Putative NAD(+)-dinitrogen-reductase ADP-D-ribosyltransferase (EC 2.4.2.37) (ADP-ribosyltransferase). Homology to draT of R. rubrum of 39% (sprot|DRAT_RHORU(SRS) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG). Pfam: DRAT no signal peptide no TMHs; High confidence in function and specificity
YP_932042.1	88% NifH.IPR000392; NitrogenaseII. Pfam:PF00142; Fer4_NifH; 1. TIGRFAMs:TIGR02016; BchX; 1.TIGR01287; nifH; 1.; High confidence in function and specificity
YP_932043.1	Nitrogenase molybdenum-iron protein alpha chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein.; High confidence in function and specificity
YP_932044.1	Nitrogenase molybdenum-iron protein beta chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein. InterPro: Oxidoreductase nitrogenase component 1 araD: L-ribulose-5-phosphate 4-epimer; High confidence in function and specificity
YP_932045.1	Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present.; High confidence in function and specificity
YP_932046.1	Ferredoxin. Pubilication: Egner et al., 2001, J Bacteriol 183, 3752-3760 (trembl|Q9F0V6) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding daimain no signal peptide no TMHs; High confidence in function and specificity
YP_932047.1	NifY protein. Homology to nifY of Azoarcus sp. BH72 of 99% (gi|11493644|gb|AF200742.1|AF200742(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs.; Function unclear
YP_932048.1	ORF1; Conserved hypothetical protein. Homology to orf1 of Azoarcus sp. BH72 of 100% (gi|11493650|gb|AAG35591.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_932049.1	Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. Pfam: PF00015; MCPsignal. SMART: SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Specificity unclear
YP_932050.1	Probable peptidylprolyl isomerase. Homology with nifM of A. chroococcum of 43% (sprot|NIFM_AZOCH) REQUIRED FOR THE ACTIVATION AND STABILIZATION OF THE IRON-COMPONENT (NIFH) OF NITROGENASE. PROBABLE PPIASE. InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain no signal peptide no TMHs hydrog_prot: hydrogenase maturation pro; High confidence in function and specificity
YP_932051.1	Nitrogen Fixation protein[nifZ], 51% identity (67% similarity) SwissProt;P14889,66% similarity to SwissProt;P23124. Has PF04319:NifZ domain;(IPR007415)This short protein is found in the nif (nitrogen fixation) operon. Its function is unknown but is probably involved in nitrogen fixation or regulating some component of this process. This 75 residue region is presumed to be a domain. It is found in isolation in some members and in the amino terminal half of the longer NifZ proteins. No Signal Peptide Or TMH reported Present.; High confidence in function and specificity
YP_932052.1	Nitrogenase stabilizing/protective protein nifW,50% identity (68% similarity) to SwissProt;P14888.TrEMBL; Q6US88(60% similarity). Has PF03206:Nitrogen fixation protein NifW;(IPR004893)Nitrogenase is a complex metalloenzyme composed of two proteins designated the Fe-protein and the MoFe-protein. Apart from these two proteins, a number of accessory proteins are essential for the maturation and assembly of nitrogenase. Even though experimental evidence suggests that these accessory proteins are required for nitrogenase activity, the exact roles played by many of these proteins in the functions of nitrogenase are unclear. Using yeast two-hybrid screening it has been shown that NifW can interact with itself as well as NifZ. No Signal Peptide or TMH present.; High confidence in function and specificity
YP_932053.1	Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present.
YP_932054.1	Serine acetyltransferase (EC 2.3.1.30). Homology to nifP of A. chrooccum of 58% (pir|D43706). PROBABLE SERINE ACETYLTRANSFERASE REQUIRED FOR OPTIMIZING THE EXPRESSION OF NITROGENASE ACTIVITY. NIFP MAY BE REQUIRED TO BOOST RATES OF SYNTHESIS OR INTRACELLULAR CONCENTRATIONS OF CYSTEINE OR METHIONINE. InterPro: Bacterial transferase hexapeptide repeat (IPR001451) no signal peptide no TMHs; High confidence in function and specificity
YP_932055.1	Homocitrate synthase is involved in the biosynthesis of the iron-molybdenum cofactor of nitrogenase and catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate into homocitrate. Similar to sprot|NIFV_AZOVI (51%) and to sprot|NIV1_ANASP (42%). Pfam (PF00682): HMG-CoA Lyase-like family InterPro (PS00815): Alpha-isopropylmalate and homocitrate synthase; High confidence in function and specificity
YP_932056.1	Cysteine desulfurase(Nitrogenase metalloclusters biosynthesis protein nifS). Homology to nifS of A. chroococcum of 71% (sprot|NIFS_AZOCH) CATALYZES THE REMOVAL OF ELEMENTAL SULFUR ATOMS FROM CYSTEINE TO PRODUCE ALANINE. SEEMS TO PARTICIPATE IN THE BIOSYNTHESIS OF THE NITROGENASE METALLOCLUSTERS BY PROVIDING THE INORGANIC SULFUR REQUIRED FOR THE FE-S CORE FORMATION. Pfam: aminotransferase class-V no signal peptide no TMHs; High confidence in function and specificity
YP_932057.1	Probable nitrogen fixation protein NifU. Homology to nifU of A. vinelandii of 67% (sprot|NIFU_AZOVI). INVOLVED IN THE FORMATION OR REPAIR OF [FE-S] CLUSTERS PRESENT IN IRON-SULFUR PROTEINS. Pfam: NifU-like N-terminal domain, NifU-like domain no signal peptide no TMHs; High confidence in function and specificity
YP_932058.1	HesB/yadR/yfhF family protein, 45% identity to TrEMBL;Q9KJL2,Q6HRJ0. SwissProt;P37026(41% identity) Has PF01521, HesB-like domain;IPR000361, HesB_yadR_yfhF;This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation.; High confidence in function and specificity
YP_932059.1	Conserved hypothetical protein. Homology to Daro03002610 of Dechloromonas aromatica of 39% (gi|41724013|ref|ZP_00150903.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_932060.1	Probable ferredoxin. Homology to fdxB of R. capsulatus of 45% (sprot|FER3_RHOCA) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership
YP_932061.1	Conserved hypothetical protein Shows similarity to hypothetical 7.7 kDa protein in fixX 3'region (ORF1) of Azorhizobium caulinodans. TIGR00162: conserved hypothetical protein
YP_932062.1	Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present.; Family membership
YP_932063.1	Hypothetical sigma-E factor regulatory protein,best similarity to SWISSPROT: sprot|Y850_HAEIN (Haemophilus influenzae, hypothetical protein hi0850) / sprot|RSEC_ECOLI (23% Escherichia coli, sigma-e factor regulatory protein RseC). TMHMM reporting 2 transmembrane helices.
YP_932064.1	Conserved hypothetical NifX protein. Homology to nifX of Azotobacter vinelandii of 47% (gi|128328|sp|P14887|NIFX_AZOVI(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs.; Conserved hypothetical protein
YP_932065.1	functions with NifE to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe
YP_932066.1	Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE. Homology to nifE of A. vielandii of 70% (sprot|NIFE_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase no signal peptide no TMHs; High confidence in function and specificity
YP_932067.1	Probale Hypothetical protein. Very Weak homology spanning the entire length of protein in the data base. No Significant domains,Features,TMH's or Signal Peptide present.; Function unclear
YP_932068.1	Conserved hypothetical protein. Has PF05484:LRV protein FeS4 cluster(IPR008665);This Iron sulphur cluster is found at the N-terminus of some proteins containing LRV repeats. Has 6,(IPR004830) PF01816:Leucine rich repeat variant;The function of this repeat is unknown. It has an unusual structure of two helices. One is an alpha helix,the other is the much rarer 3-10 helix.; Function unclear
YP_932069.1	GGDEF/EAL/PAS/PAC/GAF-domain containing protein
YP_932070.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH
YP_932071.1	Similar to TREMBL:Q82SF8 (45% identity); TREMBL:Q7P0W9 (43% identity); TREMBL:Q8XV73 (40% identity).
YP_932072.1	Putative sensory box histidine kinase,; High confidence in function and specificity
YP_932073.1	DNA-binding response regulator,; High confidence in function and specificity
YP_932074.1	Similar to TREMBL:Q89KB0 (34% identity); TREMBL:Q8XXG5 (34% identity).
YP_932075.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_932076.1	Conserved hypothetical protein, ybjQ, 65% identity to SwissProt;P75819. SwiisProt;Q8XGV2(66% identity). TrEMBL;Q83LS2( 65% identity) Has PF01906, Domain of unknown function DUF74;IPR002765; Members of this protein family have no known function. The domain is about 100 amino acids long and found in prokaryotes.; High confidence in function and specificity
YP_932077.1	Conserved hypothetical membrane protein. Hamology to PA3358 of P. aeruginosa of 56% InterPro: Integral membrane protein DUF6 Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter Pfam: Integral membrane protein DUF6 no signal peptide probable 10 TMHs; Conserved hypothetical protein
YP_932078.1	Conserved hypothetical protein,yebC,48% identity (63% similarity) to SwissProt;Q8FGR1,P24237,Q8XFD4. TrEMBL;Q9S4S9. Has PF01709, Domain of unknown function DUF28;IPR002876; This domain is found in bacterial and yeast proteins it compromises the entire length or central region of most of the proteins in the family, all of which are hypothetical with no known function. The average length of this domain is approximately 230 amino acids long.; High confidence in function and specificity
YP_932079.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide Present.
YP_932080.1	Conserved hypothetical protein. Homology to yjgR of E. coli of 66% (sprot|YJGR_ECOLI). no signal peptide no TMHs; Family membership
YP_932081.1	Probable transcriptional regulator, LysR family,; Family membership
YP_932082.1	Multidrug resistance protein B homolog. TRANSLOCASE THAT CONFERS RESISTANCE TO SUBSTANCES OF HIGH HYDROPHOBICITY (BY SIMILARITY). Presence of signal peptide and 14 transmembrane helices. Presence of DUF domains,CbiM, and bacterial cytochrome ubiquinol oxidase like domains efflux_EmrB: drug resistance transport; High confidence in function and specificity
YP_932083.1	Conserved hypothetical membrane protein. Homology to RSc2187 of R. solanacerarum of 44%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter Pfam: Intergral membrane protein DUF6 no signal peptide probable 6 TMHs; Conserved hypothetical protein
YP_932084.1	Putative methyl-accepting chemotaxis transducer,Chmtaxis_transd. Pfam: PF00015; MCPsignal. SMART: SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices. Methyl-accepting chemotaxis serine transducer. CHEMOTACTIC-SIGNAL TRANSDUCERS RESPOND TO CHANGES IN THE CONCENTRATION OF ATTRACTANTS AND REPELLENTS IN THE ENVIRONMENT TRANSDUCE A SIGNAL FROM THE OUTSIDE TO THE INSIDE OF THE CELL AND FACILITATE SENSORY ADAPTATION THROUGH THE VARIATION OF THE LEVEL OF METHYLATION. ATTRACTANTS INCREASE THE LEVEL OF METHYLATION WHILE REPELLENTS DECREASE THE LEVEL OF METHYLATION THE METHYL GROUPS ARE ADDED BY THE METHYLTRANSFERASE CHER AND REMOVED BY THE METHYLESTERASE CHEB. recN: DNA repair protein RecN; Specificity unclear
YP_932085.1	May be involved in either the transport or processing of arabinose polymers.Belongs to the major facilitator superfamily. 36% MFS.IPR005828; Sub_transporter. TMhelix:12.; High confidence in function and specificity
YP_932086.1	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 25% MFS.IPR005828; Sub_transporter.IPR005829; Sug_transporter.InterPro: General substrate transporters Pfam:PF00083; sugar_tr; 1. TMHelix: 12; Specificity unclear
YP_932087.1	Putative transcriptional regulator, LysR family,; Family membership
YP_932088.1	510-methylenetetrahydrofolate reductase InterPro: Methylenetetrahydrofolate reductase fadh2: 510-methylenetetrahydrofolate reductase; High confidence in function and specificity
YP_932089.1	Probable hemolysin.46% identity to TrEMBL;Q7NQ39. Has PF01728, FtsJ-like methyltransferase; IPR002877,RrmJFtsJ_mtfrase; This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesised that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.; High confidence in function and specificity
YP_932090.1	Hypothetical protein. Weak Homology with hits in the Database. No domains, repeats, motifs or features could be predicted above threshold value.
YP_932091.1	catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine
YP_932092.1	Conserved hypothetical secreted protein. Homology to PA0776 of Pseudomonas aeruginosa of 30% (trembl|Q9I5G2(SRS)) No domains predicted Signal Peptide present. No TMH present.; Conserved hypothetical protein
YP_932093.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_932094.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
YP_932095.1	Putative Lipid A biosynthesis acyltransferase Homology to msbB of of E. coli of 27% (AAA24181). Homology only with the N-terminus. no signal peptide. 1 TMH. Tigrfam: lipid_A_htrB, lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase. Pfam: Lip_A_acyltrans,Bacterial lipid A biosynthesis acyltransferase.; Family membership
YP_932096.1	Putative Lipid A biosynthesis acyltransferase Homology to.msbB of of E. coli of 27% (AAA24181). Homology only with the N-terminus. no signal peptide. 1 TMH. Tigrfam: lipid_A_htrB, lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase. Pfam: Lip_A_acyltrans,Bacterial lipid A biosynthesis acyltransferase.; Function unclear
YP_932097.1	Conserved hypothetical membrane protein. Homology to Daro03000819 of Dechloromonas aromatica of 32% (gi|46140899|ref|ZP_00152594.2|(NBCI ENTREZ)). No domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein
YP_932098.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_932099.1	Conserved hypothetical protein. Coils2 Program reporting presence of 1 Coiled-Coil. Has SMART;SM00065,GAF domain;This domain is present in phytochromes and cGMP-specific phosphodiesterases. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyses the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. A phytochrome is a regulatory photoreceptor which exists in 2 forms that are reversibly interconvertible by light, the PR form that absorbs maximally in the red region of the spectrum, and the PFR form that absorbs maximally in the far-red region. This domain is also found in NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.; Specificity unclear
YP_932100.1	Tyrosine recombinase xerC. Site-specific tyrosine recombinase which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region forming the heterotetrameric xerC-xerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids at ColE1 xer (or cer) and pSC101 (or psi) sites. In the complex xerC specifically exchanges the top DNA strands (By similarity).; High confidence in function and specificity
YP_932101.1	Conserved hypothetical protein. Homology to ebA3954 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA3954(KEGG)). No domains predictied. No signal peptide. No TMHs. helix-turn-helix present.
YP_932102.1	Hypothetical protein yccW TREMBL:Q8Y3C9: 52% identity, 62% similarity. InterPro; IPR002478; PUA. InterPro; IPR000051; SAM_bind. Pfam:Met_1:Met-10+ like-protein SMART; SM00359 TIGR00095: conserved hypothetical protein No transmembrane helices; High confidence in function and specificity
YP_932103.1	Conserved hypothetical membrane protein. Homology to ebA3957 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA3957(KEGG)). No domains predicted. signal peptide. 2 TMHs; Conserved hypothetical protein
YP_932104.1	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs
YP_932105.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_932106.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_932107.1	Conserved hypothetical membrane protein. Homology to BP3397 of B. pertussis of 41% (bpe:BP3397(KEGG)). Tigrfam: azlC: azlC protein (azlC). 6 TMHs no signal peptide; Conserved hypothetical protein
YP_932108.1	Conserved hypothetical membrane protein. Homology to RS04896 of Ralstonia solanacearum o 43% (trembl|Q8Y1W8) Has PF06063, Domain of unknown function (DUF931);IPR010337;Family of transmembrane proteins with undetermined function. singal peptide. 2 THMs; Conserved hypothetical protein
YP_932109.1	Hypothetical protein. Homology to Daro03002672 of Dechloromonas aromatica of 51% (gi|41723577|ref|ZP_00150487.1|(NBCI ENTREZ)). Has PF04023, FeoA domain;IPR007167; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese. no signal peptide. no TMHs
YP_932110.1	Ferrous iron transport protein B, FeoB.Probable GTP-driven transporter of ferrous ion.Invovled in iron II uptake. 29% FeoB.IPR005289; GTP-bindding_dom.IPR005225; Small_GTP. Pfam:PF02421; FeoB; 1.TIGRFAMs TIGR00437; feoB; 1.TIGR00650; MG442; 1. TIGR00231; small_GTP; 1. TMHelix:12 Siganl pepetide present.; High confidence in function and specificity
YP_932111.1	Outer membrane TonB-dependent, hydroxamate-type ferrisiderophore receptor. Probably involved in iron transport. 30% TONB_C.IPR000531; TonB_receptor.IPR010105; TonB_siderophor. InterPro: TonB-dependent receptor protein Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide present.; High confidence in function and specificity
YP_932112.1	Putative PKHD-type hydroxylase, 69% Identity(82% simialrity) to SwissProt;P59727,Q8FJM69, (48% identity) Has SMART;SM00702, P4Hc,Prolyl 4-hydroxylase alpha subunit homologues: IPR006620; Pro_4_hyd_alph; Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor. Has PF03171,2OG-Fe(II) oxygenase superfamily;IPR005123;This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site. The family also includes lysyl hydrolases,isopenicillin synthases and AlkB.; High confidence in function and specificity
YP_932113.1	Probable (S)-2-hydroxy-acid oxidase. Homology to gox of S. oleracea (spinach) of 42% (sprot|GOX_SPIOL). CATALYTIC ACTIVITY: (S)-2-hydroxy-acid + O(2) = 2-oxo acid + H(2)O(2). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Protein binding FMN and related compounds core region (IPR003009) Pfam: FMN-dependent dehydrogenase no signal peptide no TMHs guaA_Cterm: GMP synthase C-terminal d; Family membership
YP_932114.1	Putative outer membrane efflux protein. Homology to orpM in P. aeruginosa of 36%. Component of an efflux system that confers multidrug or multible antibiotic resistence. Interpro: Outer membran efflux protein Pfam: Outer membran efflux protein signal peptide no TMHs; Family membership
YP_932115.1	Putative efflux transporter for macrolide antibiotics, TREMBL:Q92NU9 (57% identity); TREMBL:Q884D4 (49% identity). Pfam (PF00005): ABC transporter. Pfam (DUF214): Predicted permease. TMHMM reporting four transmembrane helices. TC (3.A.1.122): The Macrolide Exporter Family.; Specificity unclear
YP_932116.1	Macrolide-specific efflux protein macA precursor. Efflux transporter for macrolide antibiotics (By similarity). Membrane Fusion Protein (MFP) family.; High confidence in function and specificity
YP_932117.1	Probable fiopolymer transport protein ExbD. Homology to exbD1 of X. campestris of 43%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; High confidence in function and specificity
YP_932118.1	Probable biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 50% ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: MotA/TolQ/ExbB proton channel family Pfam: MotA/TolQ/ExbB proton channel family no signal peptide no TMHs; Family membership
YP_932119.1	Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear
YP_932120.1	Bacterioferritin (BFR)(Cytochrome B-1)(Cytochrome B-557).May perform analogous functions in iron detoxification and storage to that of animal ferritins.Key role in iron homeostasis. 71% Bacterioferritin.IPR008331; Ferritin_Dps.IPR009040; Ferritin_like. Pfam:PF00210; ferritin; 1. TIGRFAMs:TIGR00754; bfr; 1.; High confidence in function and specificity
YP_932121.1	Bacterioferritin-associated ferredoxin. Homology to psto4159 of P. syringae of 33% (trembl|Q87XL9). SEEMS TO ASSOCIATE WITH BFR; COULD BE A GENERAL REDOX AND/OR REGULATORY COMPONENT PARTICIPATING IN THE IRON STORAGE MOBILIZATION FUNCTIONS OF BFR. COULD PARTICIPATE IN THE RELEASE OR THE DELIVERY OF IRON FROM/TO BACTERIOFERRITIN (OR OTHER IRON COMPLEXES). Pfam: BFD-like [2Fe-2S] binding domain no signal peptide no TMHs; Conserved hypothetical protein
YP_932122.1	47% DUF1008. Pfam:PF06228; DUF1008; 1.; High confidence in function and specificity
YP_932123.1	Similar to TREMBL:Q8Y2F3 (57% identity); TREMBL:Q7VVV4 (55% identity); TREMBL:Q9I111 (53% identity). Pfam (FAA_hydrolase): Fumarylacetoacetate (FAA) hydrolase family.
YP_932124.1	Conserved hypothetical secreted protein. Homology to an orf of G. sulfurreducens of 34% (tremblnew|AAR35905(SRS)). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein
YP_932125.1	Conserved hypothetical secreted protein. Homology to ebA1833 of Azoarcus sp. EbN1 of 48% (gnl|keqq|eba:ebA1833(KEGG)). No domains predicted. Signal peptide Present. No TMH present.; Conserved hypothetical protein
YP_932126.1	Conserved hypothetical signaling protein. Homology to ebA1830 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA1830(KEGG)). Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. PF00672 HAMP. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. TMHMM reporting 2 transmembrane helices of which one is in the signal peptide. Signal peptide present.; Conserved hypothetical protein
YP_932127.1	Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. 40% Malonyl_CoA_deC. Pfam:PF05292; MCD; 1.; High confidence in function and specificity
YP_932128.1	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.
YP_932129.1	Hypothetical two-component system response regulator, very low similarity to a part of YehT: SWISSPROT: sprot|YEHT_ECOLI (16% Escherichia coli, YehT) Pfam: PF00072 Response_reg.
YP_932130.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_932131.1	Conserved hypothetical protein, 47% identity (59% similarity)to TrEMBL;Q8FIR0.TrEMBL;Q83LI7 Has PF04337,Protein of unknown function, DUF480;IPR007432;This family consists of several proteins of uncharacterised function. Coils2 program reporting presence of Coiled-Coil.; High confidence in function and specificity
YP_932132.1	Putative adenylate/guanylate cyclase,; Conserved hypothetical protein
YP_932133.1	Conserved hypothetical secreted protein. Homology to Daro03000403 of Dechloromonas aromatica of 37% (gi|46140621|ref|ZP_00152222.2|(NBCI ENTREZ)). InterPro: Bacterial outer membrane protein (IPR006664). Pfam: OmpA family. signal peptide. no TMHs; Conserved hypothetical protein
YP_932134.1	Conserved hypothetical secreted protein. Homology to PJS6w01004783 of Polaromonas sp. JS666 of 45% (gi|54028512|ref|ZP_00360661.1|(NBCI ENTREZ)). No domains predicted. signal peptide. TMH in signal peptide.; Conserved hypothetical protein
YP_932135.1	HD-domain containing protein
YP_932136.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_932137.1	Conserved hypothetical protein. Homology to Mflag03001107 of Methylobacillus flagellatus of 42% (gi|53759956|ref|ZP_00350342.1|(NBCI ENTREZ)). No Signal peptide or TMH present. No domains predicted.
YP_932138.1	Conserved hypothetical protein. Homology to NE1890 of N.europaea of 35% (tremble:Q82TJ7) Has PF05164, Family of unknown function (DUF710);IPR007838;Family of eubacterial hypothetical proteins. No signal peptid. No TMHs
YP_932139.1	Hypothetical protein, 72% identity(81% similarity) to TrEMBL;Q82TJ8. TrEMBL;Q8XWR7(62% identity). Has PF04543, Family of unknown function (DUF589);IPR007628 ;Family of uncharacterised proteins; Function unclear
YP_932140.1	Conserved hypothetical membrane protein. TREMBL:Q82TJ9: 43% identity, 59% similarity InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81 no signal peptide. 8 TMHs; Conserved hypothetical protein
YP_932141.1	Hypothetical protein Extremely poor homology with hits in the DB. NO features/signal Peptide/Domains present.
YP_932142.1	Conserved hypothtecial protein. Homology to Avin02002811 of Azotobacter vinelandii of 50% (gi|23103464|ref|ZP_00089946.1|(NBCI ENTREZ)). InterPro: Domain of unknown function DUF224 (IPR004017). no signal peptide. no TMHs
YP_932143.1	Hypothetical protein. 22% identity to SwissProt;P45905 No domains, repeats, motifs or features present.
YP_932144.1	Part of the ABC transporter complex mntABC involved in manganese uptake. 41% Similar to the putative periplasmic-binding protein MntC precursor in E.coli. The MntC protein is also involved in the resistance to oxidative stress in N gonorrhoaeae. TREMBL E.coli:Q9F4F6. InterPro:IPR006128; Lipoprotein_4.IPR006127; SBP_bac_9. Pfam:PF01297; SBP_bac_9; 1. Signal peptide present.TMHelix:1 This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity
YP_932145.1	Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. Similar to the permease, MntB in Synechocystis 6803. 30% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity
YP_932146.1	Manganese transport system ATP-binding protein mntA. This protein is probably a component of a manganese permease a binding protein-dependent ATP-driven transport system (mntABC). Probably responsible for energy coupling to the transport system. 36% AAA_ATPase.IPR003439,AAA ATPase superfamily; ABC_transporter. Pfam: PF00005; ABC_tran; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity
YP_932147.1	Conserved hypothetical membrane protein. Homology to ebA1811 of Azoarcus sp. EbN1 of 38% (gi|56476415|ref|YP_158004.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_932148.1	Putative regulator protein, probably involved in the regulation of cation uptake systems. 32% FUR.IPR009058; Wing_hlx_DNA_bnd. Pfam:PF01475; FUR; 1.Fur family protein 30%; Function unclear
YP_932149.1	Conserved hypothetical protein. Homology to PSPTO4639 of P.syringae of 41% (tremble:Q87WB4) No domains predicted. No TMHs. No signal peptide
YP_932150.1	HlyB-family protein. Similar to TREMBL:Q7WBM7 (50% identity); TREMBL:Q9KKL9 (41% identity); SWISSPROT:P18770 (28% identity). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting four transmembrane helices. TC (3.A.1.109.3): LapA adhesin protein exporter, LapB.; High confidence in function and specificity
YP_932151.1	Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership
YP_932152.1	Putative DNA-binding response regulator, LuxR family,; Function unclear
YP_932153.1	Conserved hypothetical protein. Homology to ebA1795 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebA1795(KEGG)). No domains predicted. No TMHs.
YP_932154.1	Conserved hypothetical glycosyltransferase. Homology to gsu0991 of G. sulfurreducens of 30% (tremblnew|AAR34318) Pfam: Glycosyl transferase group 1 no signal peptide no TMHs; Conserved hypothetical protein
YP_932155.1	Conserved hypothetical protein. Homology to ebB52 Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebB52(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_932156.1	Conserved hypothetical GGDF domain protein. Homology to CV0310 of Chromobacterium violaceum of 34% (trembl|Q7P1A3). Has IPR003660_HAMP,SMART;SM00304:This domain is known as the HAMP domain for histidine kinases,adenylyl cyclases, methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160_GGDEF(SMART;SM00267);This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. The function of this domain is unknown, however it has been shown to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Has DUF2: This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site. It often but not always occurs along with PAS IPR000014 and DUF9 IPR000160 domains that are also found in many signalling proteins. signal peptide 1 TMH; Conserved hypothetical protein
YP_932157.1	Conserved hypothetical secreted protein. Homology to BB1185 of Bordetella bronchiseptica of 49% (trembl|Q7WN55(SRS)) Signal peptide present. No TMHs Has PF06035, Bacterial protein of unknown function (DUF920);IPR010319; This family consists of several hypothetical bacterial proteins of unknown function.; Conserved hypothetical protein
YP_932158.1	Putative outer membrane efflux protein. Homology to aggA from P. putida of 35%. The OEP family (outer membrane efflux protein) allow export of a variety of substrates in Gram negative bacteria. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Function unclear
YP_932159.1	Putative two-component sensor histidine kinase. TrEMBL; Q87XU6( 47% identity, 64% similarity),Q6F9J5(43% identity,61% similarity),Q6NAD6(44% Identity,61% similarity). TMHMM2 reporting 2 TMH's present. No Signal peptide Present. Has PF02133;Permease for cytosine/purines, uracil, thiamine, allantoin: IPR001248;Cyt_pur_permease:The Nucleobase Cation Symporter-1 (NCS1) family consists of bacterial and yeast transporters for nucleobases including purines and pyrimidines. Members of this family possess twelve putative transmembrane a-helical spanners (TMSs). At least some of them have been shown to function in uptake by substrate:H+ symport mechanism. Has PF07578:Lipid A Biosynthesis N-terminal domain;This family is found at the N-terminus of a group of Chlamydial Lipid A biosynthesis proteins. It is also found by itself in a family of proteins of unknown function. Has SMART;SM00388:(IPR003661)Dimerisation and phosphoacceptor domain of histidine kinases.The histidine kinase A (phosphoacceptor) N-terminal domain is a dimerisation and phosphoacceptor domain of histidine kinases. It has been found in bacterial sensor protein/histidine kinases. IPR003594;ATPbind_ATPase;(SM00387)This domain is found in several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins. SM00448;IPR001789;Response_reg:This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.; High confidence in function and specificity
YP_932160.1	Putative transcriptional regulator, LuxR family,Response_reg. IPR000792; HTH_LuxR. Pfam: PF00072; response_reg. PF00196; GerE. SMART: SM00448; REC. SM00421; HTH_LUXR. HTH reporting reporting nucleic acid binding motif.; Family membership
YP_932161.1	Conserved hypothetical membrane protein. Homology to Raeut03005995 of Ralstonia eutropha of 34% (gi|53760601|ref|ZP_00350538.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 10 TMHs; Conserved hypothetical protein
YP_932162.1	Hypothetical membrane protein. No homology of the entire protein to the data bank. No domains predicted. No signal peptide. 12 TMHs
YP_932163.1	Probable glutathione-disulfide reductase. Homology to gor of E. coli of 53% (sprot|GSHR_ECOLI). Maintain high levels of reduced glutathione in the cytosol. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); NAD binding site (IPR000205); Pyridine nuclotide-disulfide oxidoreductase dimerisation doamin (IPR004099); Pyridine nucleotide-disulphide oxidoreductase, class I (IPR001100) Pfam: Pyridine nuccleotide-dusulfphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase dimerisation domain no signal peptide no TMHs; High confidence in function and specificity
YP_932164.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q87G83 (52% identity); TREMBL:Q9K1A3 (61% identity); SWISSPROT:Q57180 (60% identity). Pfam (PF00005): ABC transporter. TMHMM reporting five transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear
YP_932165.1	Hypothetical protein ygjP. TREMBL:Q83JJ6: 60% identity,74% similarity (probable metal dependent hydrolase) Members of this family are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C terminus being the most conserved region, containing three conserved histidines InterPro:IPR002725; DUF45. Pfam:PF01863; DUF45 Non secretory protein with probability of signal peptide being 0.243 No transmembrane helices gmhA: phosphoheptose isomerase; High confidence in function and specificity
YP_932166.1	conserved hypothetical secreted protein. Homology to bA4595 of Azoarcus sp. EbN1 of 52% (gnl|keqq|eba:ebA4595(KEGG)) . No domains predicted. No TMHs. Signal Peptide present.; Conserved hypothetical protein
YP_932167.1	Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. Entry name Q8PQ18 Primary accession number: Q8PQ18 InterPro IPR000462; CDP-OH_P_trans. Pfam PF01066; CDP-OH_P_transf; 1. Identities = 114/203 (56%),Prediction: Signal peptide Signal peptide probability: 0.988 Number of predicted TMHs: 3; Family membership
YP_932168.1	Similar to TREMBL:Q87TY0 (64% identity); TREMBL:Q8PQ17 (61% identity); SWISSPROT:P76092 (55% identity).
YP_932169.1	Entry name:- Q9I0U5 Primary accession number:-Q9I0U5 InterPro:- IPR008934; AcPase_VanPerase. IPR000340; DS_phosphatase. IPR000326; PA_PTPase. Number of predicted TMHs: 8 Prediction: Non-secretory protein Signal peptide probability: 0.061 IPR000387; TYR_phosphatase. Pfam PF00782; DSPc; 1. PF01569; PAP2; 1. Identity:- 58%
YP_932170.1	Conserved hypothetical membrane protein. Homology to PA2538 of Pseudomonas aeruginosa of 36% (trembl|Q9I0U6). No domains predicted. No signal peptide. 3 TMHs; Conserved hypothetical protein
YP_932171.1	FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-acyl carrier protein as the fatty acyl donor. CATALYTIC ACTIVITY: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name:-SWISSPROT:PLSC_ECOLI Prim. accession # P26647 InterPro:-IPR002123; Acyltransferase. IPR004552; AGP_acyltrn. Pfam:-PF01553; Acyltransferase; 1. Identities = 42/127 (33%) Prediction: Non-secretory protein Signal peptide probability: 0.014 Number of predicted TMHs: 0; Family membership
YP_932172.1	Conserved hypothetical phoshpatidate cytidyltransferase. Homology to pa2536 of P. aeruginosa (trembl|Q9I0U8). Phosphatidate cytidylyltransferase is the enzyme that catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate (PA): CTP + phosphatidate = diphosphate + CDP-diacylglycerol Pfam: Phospatidate cytidyltransferase signal peptide 7 TMHs InterPro: Phosphatidate cytidylyltransferase stp: serine transporter; Family membership
YP_932173.1	Probable cytochrome c-type protein NapC. Homology to napC of r. sphaeroides of 67% (sprot|NAPC_RHOSH). MEDIATES ELECTRON FLOW FROM QUINONES TO THE NAPAB COMPLEX. signal peptide no TMHs; High confidence in function and specificity
YP_932174.1	probable diheme cytochrome c. Homology to napB of A. eutrophus of 51% (sprot|NAPB_ALCEU). SMALL SUBUNIT OF THE PERIPLASMIC NITRATE REDUCTASE (NAP). ONLY EXPRESSED AT HIGH LEVELS DURING AEROBIC GROWTH. NAPAB COMPLEX RECEIVES ELECTRONS FROM THE MEMBRANE-ANCHORED TETRAHEME NAPC PROTEIN THUS ALLOWING ELECTRON FLOW BETWEEN MEMBRANE AND PERIPLASM. ESSENTIAL FUNCTION FOR NITRATE ASSIMILATION AND MAY HAVE A ROLE IN ANAEROBIC METABOLISM. signal peptide no TMHs; High confidence in function and specificity
YP_932175.1	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC
YP_932176.1	Putative NapD protein, component of of periplasmic nitrate reductase system. Plays a role in the correct assembly of subunits of the periplasmic napAB enzyme. Homology to napD of Rhodobacter sphaeroides of 26% (gi|3345484|dbj|AB016290.1|). InterPro:IPR005623; NapD. Pfam:PF03927; NapD; 1. no signal peptide. No TMHs.; Function unclear
YP_932177.1	Putative periplasmic nitrate reductase accessory protein NapE. Homology to napE of R. sphaeroides of 36% (trembl|O88159). Pfam: Periplasmic nitrate reductase NapE (PF06796) This family consists of several bacterial periplasmic nitrate reductase NapE proteins. NapE is thought to be a transmembrane protein of the reductase. Interpro: Periplasmic nitrate reductase NapE (IPR010649) no signal peptide 1 TMH; Family membership
YP_932178.1	AmiC regulates the expression of the inducible aliphatic amidase activity in Pseudomonas aeruginosa. Similar to trembl|Q87VQ0 (80%) and to sprot|AMIC_PSEAE (27%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_932179.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q87VP9 (50%)and to pir|AB0146 (48%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting nine Tmhelix. SignalP reporting Signal peptide.; Specificity unclear
YP_932180.1	Probable ABC transporter membrane spanning protein. Homology to urtC of Anabaena sp. of 41% (involved in urea transport). Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system signal peptide probable 9 TMHs; Function unclear
YP_932181.1	Conserved hypothetical ABC transporter ATP binding protein. Homology to pp4844 of P. putida of 70% (trembl|Q88DI1). Probable component of a branched-chain amino-acid transport system. Pfam: ABC-Transporter no signal peptide no TMHs; Family membership
YP_932182.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q88DI0 (59%) and to sprot|BRAG_PSEAE (35%). Pfam: ABC transporter Smart: AAA ATPases; Specificity unclear
YP_932183.1	Probable nodulation protein,; Function unclear
YP_932184.1	Function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotobetainyl-CoA. Entry name CAID_ECO57 Primary accession number Q8XA35 InterPro IPR001753; EnCoA_hydrtse. Pfam PF00378; ECH; 1. Identities = 30% Prediction: Non-secretory protein Signal peptide probability: 0.003 Number of predicted TMHs: 0; Family membership
YP_932185.1	Conserved hypothetical membrane protein. Homology to PP2796 of P. putida of 44% (trembl|Q88J53) PF04341,Protein of unknown function, DUF485;IPR007436;This family includes several putative integral membrane proteins. signal peptide 1 TMHs; Conserved hypothetical protein
YP_932186.1	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake
YP_932187.1	Hypothetical protein ytfL. TREMBL:Q7NQ98: 61% identity, 78% similarity InterPro IPR002550; CBS. IPR000644; CBS_domain. IPR005170; CorC_transpt-asc. Pfam: PF00571; CBS; 2. PF03471; CorC_HlyC; PF01595; DUF21; gntP: gluconate transporter Signal peptide present (Signal P predicted) Transmembrane helices 4 (TMHMM predicted); High confidence in function and specificity
YP_932188.1	Transcriptional regulator, GntR-family,; High confidence in function and specificity
YP_932189.1	MDM; functions in conversion of succinate to propionate
YP_932190.1	functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins
YP_932191.1	Activity:- ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA Entry name:-TREMBL:Q8U9Y9 Prim. accession # Q8U9Y9 InterPro:-IPR000438; ACoACC_transB. IPR000022; Carboxyl_trans. Pfam:- PF01039; Carboxyl_trans; 1. Identities = 363/511 (71%) Number of predicted TMHs: 0; Family membership
YP_932192.1	Activity:- ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA Entry name :- Q8U9Z4 Primary accession number:- Q8U9Z4 InterPro:- IPR001882; Biotin_BS. IPR005482; Biotin_carb_C. IPR000089; Biotin_lipoyl. IPR005481; CPase_L_N. IPR005479; Cphp_synth_L_D2. Pfam:- PF02785; Biotin_carb_C; 1. PF00364; Biotin_lipoyl; 1. PF00289; CPSase_L_chain; 1. PF02786; CPSase_L_D2; 1. Identities = 400/673 (59%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_932193.1	GGEF/EAL/PAS/PAC-domain containing protein, sym; pNGR234a) / TREMBL: trembl|Q7NYX4 (40% Chromobacterium violaceum, cv1148) InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001633 EAL. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain.
YP_932194.1	Conserved hypothetical protein. Homology to PA4929 of P.aeruginosa of 32% (trembl|Q9HUN5(SRS)). Signal P reporting presence of signal peptide. 7 TMHs Has PF07696: 7TMR-DISM extracellular 2; This entry represents one of two distinct types of extracellular domain found in the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules) bacterial transmembrane proteins. It is possible that this domain adopts a jelly roll fold and acts as a receptor for carbohydrates and their derivatives. Has PF07695:7TM diverse intracellular signalling domain;This entry represents the transmembrane region of the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules). Has IPR000160;GGDEF:(SM00267)This domain is found linked to a wide range of non-homologous domains. The function of this domain is unknown This domain is found in proteins which contain bacterial signaling domains. Has PF07696:7TMR-DISM extracellular 2 domain;This entry represents one of two distinct types of extracellular domain found in the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules) bacterial transmembrane proteins. It is possible that this domain adopts a jelly roll fold and acts as a receptor for carbohydrates and their derivatives.
YP_932195.1	Conserved hypothetical metallopeptidase. Homology to bpp2257 of B. parapertussis of 63% (trembl|Q7W887). Members of this family of bacterial proteins are described as hypothetical proteins or zinc metallopeptidases. The majority have a HExxH zinc-binding motif characteristic of neutral zinc metallopeptidases, however there is no evidence to support their function as metallopeptidases. Pfam: putaive neutral zinc metallopeptidase no signal peptide 1 TMH; Specificity unclear
YP_932196.1	Glyoxalase I (lactoylglutathione lyase) catalyzes the first step of the glyoxal pathway in the following reaction: glutathione + methylglyoxal = (R)-S-lactoylglutathione,; Function unclear
YP_932197.1	Probable DNA-binding response regulator,Response_reg. IPR001867; Trans_reg_C. Pfam: PF00072; response_reg. PF00486; trans_reg_C. SMART: SM00448; REC.; Specificity unclear
YP_932198.1	Putative hybrid sensor and regulator protein,; Specificity unclear
YP_932199.1	Putative ornithine utilization regulator,; Specificity unclear
YP_932200.1	Methylmalonyl-CoA mutase mitochondrial precursor (EC 5.4.99.2) (MCM). INVOLVED IN MAN IN THE DEGRADATION OF SEVERAL AMINO ACIDS ODD-CHAIN FATTY ACIDS AND CHOLESTEROL VIA PROPIONYL-COA TO THE TRICARBOXYLIC ACID CYCLE. MCM HAS DIFFERENT FUNCTIONS IN OTHER SPECIES. Activity:- (R)-2-Methylmalonyl-CoA = succinyl-CoA Entry name :-TREMBL:Q8Y2U5 Prim. accession # Q8Y2U5 Identities = 797/1103 (72%) InterPro:- IPR006159; Acid_CoA_mut_C. IPR005129; ArgK. IPR006158; B12-binding. IPR006099; MMCoA_mutase. IPR006098; MMCoA_mutase_N. Pfam:- PF03308; ArgK; 1. PF02310; B12-binding; 1. PF01642; MM_CoA_mutase; 1. Prediction: Non-secretory protein Signal peptide probability: 0.005 Number of predicted TMHs: 0; Family membership
YP_932201.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs
YP_932202.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_932203.1	Hypothetical secreted protein. No significant homology to the data bank. no domains pedicted. signal peptide. TMH in signal peptide
YP_932204.1	Hypothetical protein, 52% identity to TrEMBL;Q8XYG9. Has PF03781, Domain of unknown function (DUF323);IPR005532 ;This presumed domain is found in bacterial proteins. In some cases these proteins also contain a protein kinase domain. The function of this domain is unknown. The domain has also been found in a eukaryotic protein, required for post-translational sulphatase modification.; Function unclear
YP_932205.1	(N-acetyl-beta-glucosaminidase)(Beta-N- acetylhexosaminidase). Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity). Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D-glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta-GlcNAc, and slightly active on p-nitrophenyl-beta-GalNAc. May play a role in signal transduction between host and organism. 34% Glyco_hydro_3N. Pfam:PF00933; Glyco_hydro_3; 1. TMhelix:2.; High confidence in function and specificity
YP_932206.1	CreD confers tolerance to colicin E2. Similar to SWISSPROT:P08369 (35% identity). TMHMM reporting six transmembrane helices.; High confidence in function and specificity
YP_932207.1	part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation
YP_932208.1	response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation
YP_932209.1	Probable magnesium transporter MgtE. Members of this family probably transport Mg2+ or other divalent cations into the cell. 26% CBS_domain.IPR006667; MgtE_integrmembr. Pfam:PF00571; CBS; 2.PF01769; MgtE; 1. TMHleix: 3.; Function unclear
YP_932210.1	glycosyltransferase; polymerizes glycan strands in the peptidoglycan
YP_932211.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_932212.1	Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein
YP_932213.1	Putative exoribonuclease II (EC: 3.1.13.1), RNase R / VacB protein) / TREMBL: trembl|Q7P1X0 (50% Chromobacterium violaceum, probable ribonuclease ll,cv0092) InterPro: IPR001900 Ribonuclease_II. Pfam: PF00773 RNB-like protein.; Conserved hypothetical protein
YP_932214.1	Similar to TREMBL:Q8KNG7 (29% identity); TREMBL:Q8UEX8 (27% identity). Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Function unclear
YP_932215.1	Conserrved hypothetical protein. Homology to rsc2781 of R. solanacearum of 51% (trembl|Q8XVP9) Pfam: UPF0227 Despite being classed as uncharacterised proteins,the members of this family are almost certainly enzymes that are distantly related to the Abhydrolase_1. no signal peptide no TMHs
YP_932216.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_932217.1	Hypothetical protein PA1578.1. TREMBL:Q7W9P0:69% identity, 78% similarity TREMBL: Q8PDJ2: 69% identity, 74% similarity (predicted proteinase inhibitor)) Probable Fe-S cluster bearing oxidoreductase function. InterPro:IPR005358; UPF0153. Pfam:PF03692; UPF0153; High confidence in function and specificity
YP_932218.1	Conserved hypothetical protein. Homology to RPA1001 of R.palustris of 37% (tremble:Q6NB29). No domains predicted. No TMHs. No signal peptide.
YP_932219.1	Conserved hypothetical protein. Homology to DP0001 of Desulfotalea psychrophila of 43% (gnl|keqq|dps:DP0001(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_932220.1	ATP-dependent helicase hrpA. Not yet known. InterPro: DEAD/DEAH box helicase; High confidence in function and specificity
YP_932221.1	Conserved hypothetical secreted protein. Homology to ebA3912 of Azoarcus sp. EbN1 of 45% (gi|56477657|ref|YP_159246.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_932222.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_932223.1	Putative primosomal replication protein N Homology to priB of E. coli of 31% (sprot|PRIB_ECOLI) Component of the preprimosomal complex composed of priA, priB, priC,dnaB and dnaT. Upon transient interaction with dnaG it forms the primosome. Binds single-stranded DNA. Pfam: Single-stranded binding protein family (PF00436) Interpro: Single stranded binding (IPR010913) no signal peptide no TMHs; Family membership
YP_932224.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_932225.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_932226.1	Replicative DNA helicase (EC 3.6.1.-). PARTICIPATES IN INITIATION AND ELONGATION DURING CHROMOSOME REPLICATION; IT EXHIBITS DNA-DEPENDENT ATPASE ACTIVITY AND CONTAINS DISTINCT ACTIVE SITES FOR ATP BINDING DNA BINDING AND INTERACTION WITH DNAC PROTEIN PRIMASE AND OTHER PREPRIMING PROTEINS. InterPro: DnaB helicase; High confidence in function and specificity
YP_932227.1	Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity
YP_932228.1	Putative protein disulfide-isomerase. Homology to dsbC of E. coli of 29% (sprot|DSBC_ECOLI) REQUIRED FOR DISULFIDE BOND FORMATION IN SOME PERIPLASMIC PROTEINS. ACTS BY TRANSFERRING ITS DISULFIDE BOND TO OTHER PROTEINS AND IS REDUCED IN THE PROCESS. DSBC IS REOXIDIZED BY A YET UNCHARACTERIZED PROTEIN. ALSO ACTS AS A DISULFIDE ISOMERASE. signal peptide no TMHs; Family membership
YP_932229.1	Membrane-bound lytic murein transglycosylase A precursor (EC 3.2.1.-) (Murein hydrolase A) (Mlt38). MUREIN-DEGRADING ENZYME. MAY PLAY A ROLE IN RECYCLING OF MUROPEPTIDES DURING CELL ELONGATION AND/OR CELL DIVISION. OPTIMAL ACTIVITY IS BETWEEN PH 4.0 AND 4.5; LOSES ITS ACTIVITY RAPIDLY AT TEMPERATURES ABOVE 30 DEGREES CELSIUS. DEGRADES MUREIN GLYCAN STRANDS AND INSOLUBLE HIGH-MOLECULAR WEIGHT MUREIN SACCULI. ssl1: transcription factor ssl1; High confidence in function and specificity
YP_932230.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH
YP_932231.1	Conserved hypothetical ATPase family protein. Homology to bb4427 of B. bronchiseptica of 65% (trembl|Q7WF53). Pfam: ATPase family associated with various cellular activities This large family has the key feature that they share a conserved region of about 220 amino acids that contains an ATP-binding site. no signal peptide no TMHs; Conserved hypothetical protein
YP_932232.1	NUDIX hydrolase/thiamine phosphate synthase Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity). InterPro: NUDIX hydrolase TIGRFAM: mutt: mutator mutT protein; High confidence in function and specificity
YP_932233.1	Conserved hypothetical protein. Homology to RSc2830 of Ralstonia solanacearum of 53% (trembl:Q8XVK0). Has PF03884, Domain of unknown function (DUF329);IPR005584;The function of this short domain is unknown it contains four conserved cysteines and may therefore be involved in zinc binding. no TMHs. No signal peptide.
YP_932234.1	Hypothetical protein, yacF, 32% identitcal to SwissProt;P36680,Q8FL56. Has PF07072, Protein of unknown function (DUF1342);IPR009777 ;This family consists of several hypothetical bacterial proteins of around 250 residues in length. Members of this family are often known as YacF after the Escherichia coli protein P36680. The function of this family is unknown. cobA: cob(I)alamin adenosyltransferase
YP_932235.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_932236.1	Conserved hypothetical secreted protein. Homology to rs03277 of R. solanacearum of 30% (TrEMBL:Q8Y2M5). No domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_932237.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_932238.1	BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. birA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl-coa:carbon- dioxide ligase. this protein also activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins. InterPro: Biotin--acetyl-CoA-carboxylase ligase birA_ligase: biotin--acetyl-CoA-carboxyla; Specificity unclear
YP_932239.1	Nitrogen regulation protein NR(I),; High confidence in function and specificity
YP_932240.1	Nitrogen regulation protein NR(II),; High confidence in function and specificity
YP_932241.1	Conserved hypothetical secreted protein. Homology to cv3590 of C. violaceum of 39% (trembl|Q7NS37(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein
YP_932242.1	Glutamine synthetase I (GS) plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Similar to pir|G83005 (70%) and to pir|AJECQ (66%). Pfam (PF00120): Glutamine synthetase, catalytic domain Pfam (PF03951): Glutamine synthetase, beta-Grasp domain; High confidence in function and specificity
YP_932243.1	CzcD: Members of this family (TC 2.A.4) are integral membrane proteins that are found to increase tolerance to divalent metal ions such as cadmium, zinc,and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells. (Slc30a subfamily). Similar to the cobalt-zinc-cadmium resistance protein CzcD (cation efflux system protein) from Alcaligenes eutrophus (Ralstonia eutropha). SWISSPROT:CZCD_ALCEU.P13512. InterPro:IPR002524; Cation_efflux.InterPro: Cation efflux family. Pfam:PF01545; Cation_efflux; 1. TIGRFAMs:TIGR01297; CDF; 1. TMHelix: 4.; High confidence in function and specificity
YP_932244.1	Similar to Rhodanese domain protein, a sulphurtransferase involved in cyanide detoxification. InterPro: Rhodanese/cdc25 fold; Specificity unclear
YP_932245.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_932246.1	Conserved hypothetical protein. Homology to rs04427 of R. solanacearum of 55% (trembl|Q8Y267). Pfam: Endonuclease/Exonuclease/phosphatase family (PF03372). Interpro: Endonuclease/Exonuclease/phosphatase family (IPR005135). no signal peptide. no TMHs
YP_932247.1	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Affects resistance to the gyrase inhibitor novobiocin. Entry name: CLS_ECOLI Primary accession number P31071 InterPro IPR001736; PLD. Pfam PF00614; PLDc; 2 Identity:- 28% Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_932248.1	Protein yccU. TREMBL:Q982W3: 50% identity, 70% similarity. This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases. InterPro:IPR003781; CoA_binding. Pfam: PF02629; CoA_binding FRU: PTS enzyme-IIB fructose permease No signal peptide. No transmembrane helices present.; Function unclear
YP_932249.1	Putative glutamyl-tRNA synthetase-related protein,58% identity to TrEMBl; Q5P2J9,47% identity to TrEMBL; Q7NSJ1. Has PF00749, tRNA synthetases class I (E and Q),catalytic domain.Other tRNA synthetase sub-families are too dis; Specificity unclear
YP_932250.1	Hypothetical membrane protein. Homology to la0834 of L. interrogans of 25% (trembl|Q8F7U9). InterPro: Dolichyl-phosphate-mannose-protein mannosyltransferase (IPR003342). Dolichyl-phosphate-mannose-protein mannosyltransferases belong to the glycosyltransferase family 39 and are responsible for O-linked glycosylation of proteins. They catalyse the reaction: Dolichyl phosphate D-mannose + protein -> dolichyl phosphate + O-D-mannosyl-protein. Pfam: Dolichyl-phosphate-mannose-protein mannosyltransferase. signal peptide. 10 TMHs
YP_932251.1	40% GH_BNR. Pfam:PF02012; BNR; 2. TMHelix:1. Signal peptide: present.; Function unclear
YP_932252.1	Probable cellobiose phosphorylase, 31% identity to TrEMBL;Q7NYW4. Has PF04794, YdjC-like protein;IPR006879; Family of YdjC-like proteins. This region is possibly involved in the the cleavage of cellobiose-phosphate.; Function unclear
YP_932253.1	Conserved hypothetical glycosyl transferase. Homology to cc2889 of. C. crescentus (trembl|Q9A4E5). Pfam: Glycosyl transferase family 2(PF00535). Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. Interpro: Glycosyl transferase family 2 (IPR001173). no signal peptide. 2 TMHs.; Conserved hypothetical protein
YP_932254.1	Conserved hypothetical membrane protein. TREMBL:Q89QQ8: 34% identity This is a subfamily of bacterial binding-protein-dependent transport systems family, and includes transport system permeases involved in the transport across the membrane of several compounds. This entry contains the inner components of this multicomponent transport system InterPro: IPR000522; FecD. Pfam: PF01032; FecCD ncs1: NCS1 nucleoside transporter fam Nonsecretory protein with signal peptide probability 0.203 (Signal P predicted). TMHMM predicted 9 transmembrane helices.; Function unclear
YP_932255.1	Conserved hypothetical membrane protein. Homology to PA4820 of P. aeruginosa of 38% (trembl|Q9HUZ0(SRS)) Has PF04138, GtrA-like protein;IPR007267;Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. no signal peptide 4 TMHs; Conserved hypothetical protein
YP_932256.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_932257.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_932258.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_932259.1	Ribose-phosphate pyrophosphokinase (RPPK) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase); High confidence in function and specificity
YP_932260.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_932261.1	conserved hypothetical outer-membrane lipoprotein. Homology to lolB of C. violaceum of 32% (sprot|LOLB_CHRVO) Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein (By similarity). Tigrfam: lolB: outer membrane lipoprotein LolB Pfam: outer membrane lipoprotein LolB signal peptide no TMHs; Family membership
YP_932262.1	Conserved hypothetical secreted protein. Homology to cv4061 of C. violaceum of 37% (trembl|Q7NQS6). InterPro: TPR repeat (IPR001440) signal peptide no TMHs; Conserved hypothetical protein
YP_932263.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_932264.1	TREMBL:Q8Y2D6:42% identity, 59% similarity Hypothetical protein in xynA 3region (ORF6) (Fragment). Pfam:dynamin_2 :Dynamin central region; FH2:Formin Homology 2 Domain surE: stationary-phase survival prote No transmembrane helices(TMHMM predicted); Function unclear
YP_932265.1	Probable ferredoxin. Homology to fdx of C. vinosum of 67% (sprot|FER_CHRVI). Ferredons are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership
YP_932266.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_932267.1	Putative methylase; Family membership
YP_932268.1	Hypothetical zinc protease-like protein y4wB. TREMBL:Q8Y2E8: 43% identity; 57% similarity. InterPro: Insulinase family (Peptidase family M16) InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. Pfam:PF00675; Peptidase_M16 (Insulinase); homoserine_dh; aldehyde dehydrogenase; PF05193:Peptidase_M16_C; precor6x_red: precorrin-6x reductase TIGRFAM:folate/biopterin transporter SignalP predicted signal peptide and TMHMM predicted transmembrane helix; Specificity unclear
YP_932269.1	TREMBL:Q8Y2E9: 55% identity, 68% similarity. Hypothetical zinc protease y4wA. InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. cofactor:binds 1 zinc ion per subunit (by similarity). belongs to peptidase family m16. similarity:to y4wb. Pfam:PF00675; Peptidase_M16; 1. PF05193:Peptidase_M16_C TIGRFAM: uxuA SignalP predicted signal peptide and TMHMM predicted transmembrane helices menD: 2-succinyl-6-hydroxy-24-cyclohex; Specificity unclear
YP_932270.1	Probable signal recognition particle-docing protein FtsY Homology to ftsY of C. violaceum of 65% (trembl|Q7NQD7) In E.coli, ftsY is an essential gene located in an operon with cell division genes ftsE and ftsX, but its apparent function is as the signal recognition particle docking protein. Pfam: SRP54-type protein, helical bundle domain (PF02881); SRP54-type protein, GTPase domain Tigrfam: ftsY: signal recognition particale-docking protein FtsY no signal peptide no TMHs; High confidence in function and specificity
YP_932271.1	High confidence in function and specificity
YP_932272.1	Putative cell division protein FtsX. Homology to ftsX of E. coli of 33% (sprot|FTSX_ECOLI). FtsX is an integral membrane protein encoded in the same operon as signal recognition particle docking protein FtsY and FtsE. Might be a permease. Tigrfam: ftsX: cell division ABC transporter protein probable signal peptide probable 4 TMHs; Family membership
YP_932273.1	Alkyl hydroperoxide reductase subunit C. Homology to aphC of X. campestris of 84% (trembl|O06464). Directly reduces organic hydroperoxides in its reduced dithiol form. InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (IPR000866) Pfam: AhpC/TSA family no signal peptide no TMHs; High confidence in function and specificity
YP_932274.1	Alkyl hydroperoxide reductase subunit F. Homology to aphF of X. campestris of 71% (sprot|AHPF_XANCH) Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AHPC protein. Pfam: Pyridine nucleotide-disulphide oxidareductase no TMHs; High confidence in function and specificity
YP_932275.1	Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase
YP_932276.1	Ribonuclease H (EC 3.1.26.4) (RNase H). This enzyme is an endonuclease that degrades the RNA of RNA-DNA hybrids specifically (By similarity). InterPro: RNase H; High confidence in function and specificity
YP_932277.1	Hypothetical protein , 32% identity to TrEMBL;Q8NZP4 No domains, repeats, motifs or features present.
YP_932279.1	Putative DNA-invertase from lambdoid prophage Rac. InterPro: Site-specific recombinase Pfam: Resolvase; Family membership
YP_932280.1	Family membership
YP_932281.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_932282.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_932283.1	PhoH-like protein,; High confidence in function and specificity
YP_932284.2	contains unknown N-terminal domain/putative metalloprotease C-terminal domain
YP_932285.1	Magnesium and cobalt efflux protein corC. Plays a role in the transport of magnesium and cobalt ions. Also mediates transport of cobalt and nickel. 43% CBS_domain.IPR005170; CorC_transpt-asc. Pfam:PF00571; CBS; 2.PF03471; CorC_HlyC; 1. Belongs to the UPF0053 family.Contains 2 cbs domains.; High confidence in function and specificity
YP_932286.1	Putative apolipoprotein N-acyltransferase. Homology to cutE of E. coli of 36% (sprot|LNT_ECOLI). Transfers the fatty acyl group on membrane lipoproteins. InterPro: Apolipoprotein N-acyltransferase (IPR004563); Carbon-nitrogen hydrolase (IPR003010) Tigrfam: lnt: apolipoprotein N-acyltransferase Pfam: Carbon-nitrogen hydrolase signal peptide 6 TMHs; High confidence in function and specificity
YP_932287.1	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q7NHP0 (27% identity); SignalP predicting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership
YP_932288.1	AcrB/AcrD/AcrF family protein. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9A3K6 (38% identity); TREMBL:Q89XF8 (40% identity). InterPro (IPR001036): Acriflavin resistance protein. Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear
YP_932289.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_932290.1	Glycyl-tRNA synthetase beta chain (EC 6.1.1.14) (Glycine--tRNA ligase beta chain) (GlyRS).; High confidence in function and specificity
YP_932291.1	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate
YP_932292.1	Acyl-[acyl-carrier protein] can also acts as acyl donor.The animal enzyme is specific for the transfer of unsaturated fatty acyl groups. Catalytic Activity:- Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name TREMBL:Q82VB2 Prim. accession # Q82VB2 InterPro:- IPR002123; Acyltransferase. Pfam:- PF01553; Acyltransferase; 1. Identity:- 56% Prediction: Signal peptide Signal peptide probability: 0.907 Number of predicted TMHs: 1; Family membership
YP_932293.1	Probable phasin. Homology to p8 of Sphingomonas sp. A1 of 69% (gi|51773776|dbj|BAD38885.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; Family membership
YP_932294.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_932295.1	Conserved hypothetical secreted protein. Homology to rsc0410 of R. solanacearum of 42% (trembl|Q8Y2C6(SRS)) Pfam: OstA-like protein This family of proteins are mostly uncharacterised. However the family does include E. coli OstA P31554 that has been characterised as an organic solvent tolerance protein. signal peptide no TMHs; Conserved hypothetical protein
YP_932296.1	Conserved hypothetical secreted protein. Homology to ebA1318 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA1318(KEGG)). Has PF06835, Protein of unknown function (DUF1239);IPR010664;This family consists of several hypothetical bacterial proteins of around 190 residues in length. The function of this family is unknown. No TMHs. Signal peptide.; Conserved hypothetical protein
YP_932297.1	Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices.; Specificity unclear
YP_932298.1	Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity
YP_932299.1	Probable glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter). Transport system that facilitate potassium-efflux possibly by potassium-proton antiport. 50% Na_H_porter.IPR006037; TrkAC.IPR003148; TrkA_N. Pfam: PF00999; Na_H_Exchanger; 1.PF02080; TrkA_C; 1.PF02254; TrkA_N; 1. TMhelix: 11.; High confidence in function and specificity
YP_932300.1	Conserved hypothetical membrabe protein. Homology to Mflag03002444 of Methylobacillus flagellatus of 48% (gi|46120631|ref|ZP_00201765.1|(NBCI ENTREZ)). no domains predicted. No signal peptide. 1 TMHs
YP_932301.1	Conserved hypothetical secreted protein. Homology to Daro03002886 of Dechloromonas aromatica of 31% (gi|53729825|ref|ZP_00150246.2|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide.
YP_932302.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_932303.1	Hypothetical secreted protein. no homology with the data bank. no domains predicted. signal peptide. no TMHS
YP_932304.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_932305.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide present. 1 TMH present.
YP_932306.1	Type II secretory pathway component F,; Specificity unclear
YP_932307.1	Bacterial type II secretion system protein E,; Specificity unclear
YP_932308.1	Hypothetical protein. No homology to a protein of similar size. No domains predicted. No signal peptide. No TMHs
YP_932309.1	Type II secretory pathway component D, weak similarity to SWISSPROT:HOFQ_ECOLI (18%). A number of proteins are involved in the general secretion pathway (GSP); one of these is known as protein D (GSPD protein). Protein D is involved in the type II general secretion pathway within Gram-negative bacteria, a signal sequence-dependent process responsible for protein export. InterPro (PF00263): General (type II) secretion pathway (GSP) D protein; Specificity unclear
YP_932310.1	Conserved hypothetical ABC transporter ATP-binding protein. Homology to rs01335 of R. solanacearum of 67% (trembl|Q8XV69). ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. They are minimally composed of four domains, with two transmembrane domains (TMDs) responsible for allocrite binding and transport and two nucleotide-binding domains (NBDs) responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Both NBDs are capable of ATP hydrolysis. Pfam: ABC transporter (PF00005). No signal peptide. No TMHs; Family membership
YP_932311.1	Conserved hypothetical membrane protein Similar to TREMBL:Q7P0W7 (65% identity); TREMBL:Q82SF6 (65% identity); TREMBL:Q7VSZ9 (57% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
YP_932312.1	Conserved hypothetical secreted protein. Similar to TREMBL:Q8XV71 (59% identity); TREMBL:Q82SF7 (55% identity); TREMBL:Q7VSZ8 (55% identity). Pfam (PF02470): mce related protein. This family of proteins contains the mce (mycobacterial cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within,the macrophage. This family contains proteins of unknown function from other bacteria. SignalP reoprting signal peptide. TMH in signal peptide; Family membership
YP_932313.1	Putative surface lipoprotein. Homology to vacJ of S. flexneri of 26% (sprot|VACJ_SHIFL) Required for intercellular spreading. Pfam: VacJ like lipoprotein signal peptide no TMHs; Family membership
YP_932314.1	Conserved hypothetical secreted protein. Similar to TREMBL:Q82SF8 (54% identity); TREMBL:Q8XV73 (42% identity); TREMBL:Q7VSZ6 (40% identity). SignalP reporting signal peptide. no TMHs; Conserved hypothetical protein
YP_932315.1	Conserved hypothetical protein. Homology to rsc2957 of R. solanacearum of 42% (trembl|Q8XV74). Pfam: STAS domain The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. no signal peptide no TMHs
YP_932316.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7P0X8 (62% identity); TREMBL:Q82SG0 (58% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership
YP_932317.1	Similar to TREMBL:Q8XV76 (69% identity); TREMBL:Q7P0X7 (66% identity); TREMBL:Q82SG1 (64% identity). InterPro (IPR000412): ABC transporter family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear
YP_932318.1	Conserved hypothetical BolA-like protein. Homology to ne2377 of N. europaea of 47% (trembl|Q82SG2). InterPro: BolA-like protein This family consist of the morphoprotein BolA from E. coli and its various homologues. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5. Pfam: BolA-like binding protein no signal peptide no TMHs; Function unclear
YP_932319.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_932320.1	Regulator of nucleoside diphosphate kinase. RNK AND SSPA CAN FUNCTIONALLY REPLACE P.AERUGINOSA ALGINATE REGULATORY GENE ALGR2. 49% 1.; High confidence in function and specificity
YP_932321.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
YP_932322.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_932323.1	Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped into subfamilies; these sequences are defined by the aminotransferases class-I pyridoxal-phosphate attachment site signature, which contains the lysine residue involved in pyridoxal-phosphate binding. Similar to pir|D83057 (55%) and to trembl|Q8P544 (55%). Pfam (PF00155): Aminotransferases class-I pyridoxal-phosphate-binding site HTH reporting nucleic acid binding motif.; Specificity unclear
YP_932324.1	catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP
YP_932325.1	NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate
YP_932326.1	Probable Hypothetical UPF0028 family protein YML059C. TREMBL:Q82SM1: 50% identity, 68% similariry InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin bioF: 8-amino-7-oxononanoate synthase Signal peptide present (SinalP predicted) TMHMM predicted TMH's; Function unclear
YP_932327.1	Penicillin-binding protein 5 precursor (PBP-5) (D-alanyl-D-alanine- endopeptidase) (DD-endopeptidase).; High confidence in function and specificity
YP_932328.1	Probable negative regulator of allantoin and glyoxylate utilization operons,; High confidence in function and specificity
YP_932329.1	Hypothetical protein. No homology to the data bank. No domains predicted. No signal peptide. No TMHs
YP_932330.1	Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A). PLAYS A CENTRAL ROLE IN ASSIMILATION OF CARBON. IT CONVERTS HYDROXYPYRUVATE TO GLYCERATE AS A KEY STEP IN THE SERINE CYCLE AND MAY ALSO PLAY AN IMPORTANT ROLE IN C2 REACTIONS BY INTERCONVERTING GLYOXYLATE AND GLYCOLATE.; Specificity unclear
YP_932331.1	Conserved hypothetical membrane protein. Homology to ORF428 of Roseateles depolymerans of 64% (tremble:BAB1967) Has PF07399:(IPR009978)Protein of unknown function (DUF1504); This family consists of several hypothetical bacterial proteins of around 440 residues in length. The function of this family is unknown.; Conserved hypothetical protein
YP_932332.1	Putative RNA pseudouridylate synthase. Homology with hits in the database only for the first half of protein. Has PF00849, RNA pseudouridylate synthase; IPR006145, PseudoU_synth; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD P33643, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA. Has SMART;SM00363, S4 RNA-binding domain;IPR002942;The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA.; Family membership
YP_932333.1	Conderved hypothetical NADH-quinone oxidoreductase chain B. Homology to nuoB of C. violaceum of 77% (trembl|Q7NUE5). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient (By similarity). Pfam: NADH ubiquinone oxidoreductase, 20 kd no signal peptide no TMHs; Family membership
YP_932334.1	Putative AraC-family transcriptional regulator,; Conserved hypothetical protein
YP_932335.1	Conserved hypothetical protein. Homology to Daro03000467 of Dechloromonas aromatica of 50% (gi|41725519|ref|ZP_00152277.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_932336.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8DJ46 (29% identity); TREMBL:Q8YZK5 (29% identity). InterPro (IPR003838): Protein of unknown function DUF214. Pfam (DUF214): Predicted permease. TMHMM reporting four transmembrane helices. TC (3.A.1.122.): The Macrolide Exporter (MacB) Family.; Specificity unclear
YP_932337.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8YZK5 (28% identity); TREMBL:Q8DJ46 (29% identity). Pfam (DUF214): Predicted permease. TMHMM reporting five transmembrane helices. TC (3.A.1.122.): The Macrolide Exporter (MacB) Family.; Specificity unclear
YP_932338.1	Putative efflux transporter for macrolide antibiotics (MacB-family). Acts in conjunction with MacA. Similar to TREMBL:Q82W68 (59% identity); TREMBL:Q8RAL4 (46% identity); SWISSPROT:P75831 (41% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter. TC (3.A.1.122): The Macrolide Exporter (MacB) Family.; Family membership
YP_932339.1	The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership
YP_932340.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_932341.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_932342.1	Conserved hypothetical puter membrane protein Homology to cv1891 of c. violaceum of 64% (trembl|Q7NWT8) InterPro: Bacterial outer membrane protein (IPR006664) Pfam: OmpA family signal peptide 2 TMHs; Family membership
YP_932343.1	SWI/SNF family helicase Pfam: Helicase conserved C-terminal domain; Specificity unclear
YP_932344.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_932345.1	Phosphomethylpyrimidine kinase (EC 2.7.4.7) (HMP-phosphate kinase) (HMP-P kinase). CATALYZES THE PHOSPHORYLATION OF HMP-P TO HMP-PP. TIGRFAM: HMP-P_kinase: phosphomethylpyrimidine kinase; High confidence in function and specificity
YP_932346.1	Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase).Involved in the reversible hydration of carbon dioxide. 40% Euk_COanhd.IPR000437; Prok_lipoprot_S.IPR006311;Tat. InterPro: belongs to the eukaryotic-type carbonic anhydrase family. Pfam:PF00194; carb_anhydrase; 1. TIGRFAMs:TIGR01409; TAT_signal_seq; 1. Signal peptide present.; High confidence in function and specificity
YP_932347.1	Conserved hypothetical transcriptional regulator. Homology to rsc0989 of r. solanacearum of 47% (CAD14691). Pfam: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II no signal peptide no TMHs bioF: 8-amino-7-oxononanoate synthase; Specificity unclear
YP_932348.1	Hypothetical secreted protein. No homology to the data base. No domain predicted. No TMHs. Signal peptide.
YP_932349.1	Conserved hypothetical transcriptional regulator. Homology to RSc0698 of alstonia solanacearum of 48% (gnl|keqq|rso:RS01603(KEGG)). InterPro: IPR001647 HTH_TetR. Pfam: PF00440 Bacterial regulatory proteins,tetR family. HTH reporting nucleic acid binding motif. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_932350.1	Similar to TREMBL:Q7NR61 (35% identity); TREMBL:Q8XYV3 (33% identity); TREMBL:Q88MQ4 (32% identity). InterPro (IPR006143): Secretion protein HlyD. SignalP predicting signal peptide. TC (2.A.6.1): The Heavy Metal Efflux (HME) Family.; Family membership
YP_932351.1	AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9A7D5 (35% identity); TREMBL:Q9HXW4 (55% identity). Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear
YP_932352.1	Putative protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). InterPro: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (IPR000682), SAM binding motif (IPR000051) Tigrfam: pimt: protein-L-isoaspartate O-methyltransfase Pfam: Protein-L-isoaspartate (D-aspartate) O-methyltransferase no signal peptide no TMHs; High confidence in function and specificity
YP_932353.1	Putative rhodanese-related sulfurtransferase. TIGR:NMB1884. InterPro:IPR001763; Rhodanese-like. InterPro: Rhodanese/cdc25 fold. Pfam:PF00581; Rhodanese; 1.; Function unclear
YP_932354.1	Putative outer membrane effluxe protein protein. Homology to tolC from E. coli of 33%. The OEP family (outer membreane effluxe protein) allow export of a variety of substrates in Gram negative bacteria. TolC is believed to be a membre af an ABC transporter system for protein secretion without cleavage of a signal sequence. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership
YP_932355.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
YP_932356.1	Probably involved in the biosynthesis of exopolysaccharides. 68% Epimerase_Dh.IPR008089; Nuc_sugar_epim. Pfam:PF01370; Epimerase; 1.; High confidence in function and specificity
YP_932357.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
YP_932358.1	Function:-Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). CATALYTIC ACTIVITY: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name:- PLSC_NEIGO Primary accession number :- Q59601 InterPro IPR002123; Acyltransferase. IPR004552; AGP_acyltrn. Pfam PF01553; Acyltransferase; 1. Identities = 68/182 (37%) Prediction: Non-secretory protein Signal peptide probability: 0.096 Number of predicted TMHs: 0; Family membership
YP_932359.1	Conserved hypothetical protein. Homology to cv0660 of C. violaceum of 59% (trembl|Q7P0A7) no domains predicted no singal peptide no TMHs
YP_932360.1	Similar to amylovoran biosynthesis glycosyl transferase amsK (EC 2.-.-.-). INVOLVED IN THE BIOSYNTHESIS OF AMYLOVORAN WHICH FUNCTIONS AS A VIRULENCE FACTOR. Similar to protein annotated as sulfolipid sulfoquinovosyldiacylglycerol biosynthesis proteins.; Family membership
YP_932361.1	38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1.; Specificity unclear
YP_932362.1	Outer membrane lipoprotein SlyB. Homology to slyB of E. coli of 32% (sprot|SLYB_ECOLI) no domains predicted signal peptide no TMHs; Family membership
YP_932363.1	Probable Diacylglycerol kinase. Homology to dgkA of E. coli of 40% (sprot|KDGL_ECOLI) RECYCLING OF DIACYLGLYCEROL PRODUCED DURING THE TURNOVER OF MEMBRANE PHOSPHOLIPID (BY SIMILARITY). Pfam: prokaryotic diacylglycerol kinase no signal peptide 2 TMHs; High confidence in function and specificity
YP_932364.1	Hypothetical protein. No Domains,Features,Signal Pepetide or TMH reported Present. Most top hits suggest the possibillity of Transmembrane protein, but due to non existance of any TMH's domains it cant be considered as a choice.; Specificity unclear
YP_932365.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_932366.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_932367.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_932368.1	Function:-Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP). THIS PROTEIN IS A COMPONENT OF THE ACETYL COENZYME A CARBOXYLASE COMPLEX; FIRST BIOTIN CARBOXYLASE CATALYZES THE CARBOXYLATION OF THE CARRIER PROTEIN AND THEN THE TRANSCARBOXYLASE TRANSFERS THE CARBOXYL GROUP TO FORM MALONYL-COA. Entry name:-SWISSPROT:BCCP_ECOLI Prim. accession # P02905 InterPro :-IPR001249; AcCoA_biotinCC. IPR001882; Biotin_BS. IPR000089; Biotin_lipoyl. Pfam:- PF00364; Biotin_lipoyl; 1. Number of predicted TMHs: 0 Identity:- 94/157 (59%); High confidence in function and specificity
YP_932369.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
YP_932370.1	Hypothetical thioredoxin. Homology with BPP3919 of B. parapertussis of 38%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. Tigrfam: dsbE: periplasmic protein thiol:disulfi signal peptide probable 1 TMHs; Family membership
YP_932371.1	Conserved hypothetical protein, 39% identity to TrEMBL;Q8XVP7; Signal Peptide present. Coils2 program reporting presence of coiled coil. No TMH present. TIGR00004: endoribonuclease L-PSP putat
YP_932372.1	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso- diaminopimelate ligase (EC 6.3.2.-) (Murein peptide ligase). REUTILIZES THE INTACT TRIPEPTIDE L-ALANYL-GAMMA-D- GLUTAMYL-MESO-DIAMINOPIMELATE BY LINKING IT TO UDP-N-ACETYLMURAMIC ACID. InterPro: Cytoplasmic peptidoglycan synthetases N-terminal ispD: 4-diphosphocytidyl-2C-methyl-D-er; High confidence in function and specificity
YP_932373.1	Conserved hypothetical secreted protein. Homology to rsc3264 of R. solanacearum (trembl|Q8XUC7). Smart: Bacterial OsmY and nodulation domain (BON) The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins; outside of this group the distribution is more disparate. signal peptide TMH in signal peptide; Conserved hypothetical protein
YP_932374.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
YP_932375.1	Conserved hypothetical protein. Homology to pa4424 of P. aeruginosa of 44% (pir|H83091). Pfam: Uncharacterised protein family UPF0102 (PF02021). Interpro: Protein of unkown function UPF0102 (IPR003509). no signal peptide. no TMHs.
YP_932376.1	Conserved hypothetical protein. Homology to pp1326 of P. putida of 56% ((AAN66950). InterPro: Uncharacterized protein family UPF0011 (IPR008189) TIGR00096: conserved hypothetical protein Pfam: Tetropyrrole (Crrin/Porphyrin) methyltransferase no signal peptide no TMHs
YP_932377.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_932378.1	Conserved hypothetical secreted protein. Homology to Daro03003273 of Dechloromonas aromatica of 35% (gi|41723286|ref|ZP_00150229.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_932379.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_932380.1	S-adenosyl-methyltransferase mraW (EC 2.1.1.-). Exhibits a S-adenosyl-dependent methyltransferase activity (By similarity). TIGR00006: conserved hypothetical prote; High confidence in function and specificity
YP_932381.1	Putative cell division protein FtsL. Homology to ftsL of E. coli of 32% (sprot|FTSL_ECOLI). Protein involved in cell division and cell growth. May play some role in coupling cell division and peptidoglycan physiology. Pfam: Cell division protein FtsL signal peptide no TMHs; Family membership
YP_932382.1	Probable peptidoglycan glycosyltransferase. Homology to ftsI of E. coli of 43% (sprot|FTSI_ECOLI) Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates. InterPro: Penicillin binding protein transpeptidase domain (IPR001460) Pfam: Penicillin-binding protein dimerisation domain; Penicillin binding proetin transpeptidas domain signal peptide no TMHs; High confidence in function and specificity
YP_932383.1	Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase Homology to murE of E. coli of 40% (sprot|MURE_ECOLI) Cell wall formation. Diaminopimelic acid adding enzyme (By similarity). Pfam: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase no signal peptide no TMHs; High confidence in function and specificity
YP_932384.1	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10) (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme). Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity). InterPro: Cytoplasmic peptidoglycan synthetases N-terminal mobB: molybdopterin-guanine dinucleot; High confidence in function and specificity
YP_932385.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_932386.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_932387.1	This is a septum-peptidoglycan biosynthetic protein involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division.; High confidence in function and specificity
YP_932388.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_932389.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_932390.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_932391.1	Putative cell division protein FtsQ. Homology to ftsQ of E. coli of 23% (Sprot:FTSQ_ECOLI) This protein may be involved in septum formation. Pfam: Cell division protein FtsQ no signal peptide 1 TMHs; Family membership
YP_932392.1	This protein may be involved in anomalous filament growth. May be a component of the septum. It may interact with ftsZ. InterPro: Cell division protein FtsA; High confidence in function and specificity
YP_932393.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_932394.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
YP_932395.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 1 TMH
YP_932396.1	Conserved hypothetical protein. Homology to CV4285 of C.violaceum of 32% (tremble:Q7NQ55). No domains predicted. No TMHs No signal peptide.
YP_932397.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_932398.1	GAF-domain containing protein,; Conserved hypothetical protein
YP_932399.1	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
YP_932400.1	Putative phosphoprotein phosphatase,; Conserved hypothetical protein
YP_932401.1	Hypothetical secreted protein. Homology to pp3428 of P. putida of 26% (tremble:Q88HD2). Domain structure: 111 aa - 157 aa LysM; 232 aa - 313 aa TRP. Pfam: LysM domain; TRP. signal peptide. no TMHs
YP_932402.1	Putative serine/threonine protein kinase,; Family membership
YP_932403.1	Hypothetical membrane protein. No good homology to a protein of similar size of the data bank. Pfam: FHA domain (PF00498). The forkhead-associated (FHA) domain is a putative nuclear signalling domain found in a variety of otherwise unrelated proteins. The FHA domain comprise approximately 55 to 75 amino acids and contains three highly conserved blocks separated by divergent spacer regions.To date, genes encoding FHA-containing proteins have been identified in eubacterial and eukaryotic but not archaeal genomes. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins,transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes - DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples. Interpro: Forkhead-associated (IPR000253). no signal peptide. 1 TMHs
YP_932404.1	protein associated with Co2+ and Mg2+ efflux
YP_932405.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_932406.1	Conserved hypothetical protein. Homology to RS03757 of R.solanacearum of 44% (tremble:Q8XS71). No domains predicted. No TMHs. No signal peptide.
YP_932407.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_932408.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_932409.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
YP_932410.1	Conserved hypothetical signal transduction protein. Homology to Daro03002984 of Dechloromonas aromatica of 39% (gi|53729872|ref|ZP_00150342.2|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs; Conserved hypothetical protein
YP_932411.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_932412.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_932413.1	Transcriptional activator protein nhaR (Na+/H+ antiporter regulatory protein). Plays a role in the positive regulation of nhaA. Similar to SWISSPROT: sprot|NHAR_ECOLI (34% Escherichia coli, and Shigella flexneri, transcriptional activator protein NhaR (na+/h+ antiporter regulatory protein)) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family.; High confidence in function and specificity
YP_932414.1	Conserved hypothetical protein. Homology to ebD81 Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebD81(KEGG)). No domains predicted. No signal peptid. No TMHs
YP_932415.1	Hypothetical protein PA2604. pir:D85624: 57% identity.73% similarity SIMILARITY:Belongs to the BI1 family. InterPro:Uncharacterized protein family UPF0005 IPR006213; Bax_inhbtr1. IPR006214; UPF0005. Pfam:ZIP: Zinc transporter Probable glutamatereceptor Signal peptide present (SignalP predicted) and transmembrane helices 7 (TMHMM predicted) Pfam:PF01027; UPF0005; InterPro: Uncharacterized protein family UPF0005 2_A_01_02: Multidrug resistance protein; Specificity unclear
YP_932416.1	Probable potassium antiporter, rosB. 38% HPr_SerP_S.IPR004771; K_eff.IPR006153; Na_H_porter. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA_N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMhelix: 12.; High confidence in function and specificity
YP_932417.1	Hypothetical protein sll0260. CBS domains are found in the intracellular regions of a number of different integral membrane proteins. Two CBS domains are found in intracellular loops of several voltage gated chloride channels. A family of magnesium transporters also contain CBS domains. TREMBL:Q8KEZ1: 61% identity, 74% similarity InterPro: Domain of unknown function DUF21 InterPro:IPR002550; CBS. IPR000644: CBS_domain. IPR005170: CorC_transpt-asc. Pfam: PF00571; CBS; 2. PF03471: CorC_HlyC; 1. PF01595: DUF21; gntP: gluconate transporter Signal peptide present Transmembrane helices 3; Specificity unclear
YP_932418.1	Tellurium resistance protein terC. Could conceivably alter the intracellular level of tellurium in a manner leading to resistance. Alternatively its presence in the membrane may provide a barrier to entry of the tellurium ions.32% TerC. Pfam: PF03741; TerC; 1. TMHelix:9.; High confidence in function and specificity
YP_932419.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_932420.1	Putative tRNA(Ile)-lysidine synthetase. Homology to tils of E.coli of 34% (gnl|keqq|eco:b0188(KEGG)). Pfam: PP-loop family. Tigrfam: tRNA(Ile)-lysidine synthetase. The only examples in which the wobble position of a tRNA must discriminate between G and A of mRNA are AUA (Ile) vs. AUG (Met) and UGA (stop) vs. UGG (Trp). In all bacteria, the wobble position of the tRNA(Ile) recognizing AUA is lysidine, a lysine derivative of cytidine. This family describes a protein domain found, apparently, in all bacteria in a single copy. Eukaryotic sequences appear to be organellar. The domain archictecture of this protein family is variable; some, including characterized proteins of E. coli and B. subtilis known to be tRNA(Ile)-lysidine synthetase, include a conserved 50-residue domain that many other members lack. This protein belongs to the ATP-binding PP-loop family ( PF01171). It appears in the literature and protein databases as TilS, YacA, and putative cell cycle protein MesJ (a misnomer). No signal peptide. No TMHs.; Family membership
YP_932421.1	C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity
YP_932422.1	C4-dicarboxylate transport sensor protein,; High confidence in function and specificity
YP_932423.1	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 70% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present. TMhelix:1; High confidence in function and specificity
YP_932424.1	The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 45% DctQ. Pfam:PF04290; DctQ; 1. TMhelix:4.; High confidence in function and specificity
YP_932425.1	The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 60% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. TMhelix:13. Signal peptide: present.; High confidence in function and specificity
YP_932426.1	DedA family protein, 57% identity(75% similarity) to TrEMBL;Q88QF4. TrEMBl;Q889M5(57% identity). SwissProt;P09548(55% identity) Has PF00597, DedA family;IPR000252;This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions.; High confidence in function and specificity
YP_932427.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_932428.1	Hypothetical protein yfgB. putative fe-s-cluster redox enzyme TREMBL:Q7NS85: 70% identity; 80% similarity. InterPro:IPR004383; Cons_hypoth48. IPR007197: Radical_SAM. Pfam:PF04055; Radical_SAM; No signal peptide. No transmembrane helices. TIGR00048: conserved hypothetical prote; Function unclear
YP_932429.1	Type 4 pilus biogenesis protein,; Function unclear
YP_932430.1	Transcriptional regulator , 36% identity to TrEMBL;Q88PJ8. Weak homology with other proteins spanning entire length. Prosite,PS50943; HTH_CROC1; The cro/C1-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 50-60 residues present in transcriptional regulators. The domain is named after the transcriptional repressors cro and C1 of temperate bacteriophages 434 and lambda, respectively.; Specificity unclear
YP_932431.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_932432.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_932433.1	Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present.; Specificity unclear
YP_932434.1	PQQ enzyme repeat protein, 40% identical(60% similarity)to TrEMBL;Q82XU7. Signal Peptide present. Has 6 copies SMART;SM00564, PQQ, beta-propeller repeat;IPR002372; Beta-propeller repeat occurrs in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.; Specificity unclear
YP_932435.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_932436.1	Stimulates the elongation of poly(A) tails
YP_932437.1	GTP-binding protein hflX. trembl:Q7NS94: 66% identity; 78% similarity. InterPro:IPR006073; GTP1_OBG. These proteins contain GTP-binding motifs and are GTP1OBG Pfam:MMR_HSR1:GTPase of unknown function thdF: tRNA modification GTPase TrmE No Signal peptide present (SignalP predicted) Absence of transmembrane helices (TMHMM predicted); Family membership
YP_932438.1	Putative HflK protein. Homology to hflK of E. coli of 40% (sprot|HFLK_ECOLI). hflc and hflk govern the stability of phage lambda cii protein and have been proposed to encode or regulate a cii- specific protease. Pfam: SPFH domain/band 7 family no signal peptide 1 TMH; Family membership
YP_932439.1	Conserved hypothetical protein. Homology to hflC of E. coli of 37% (sprot|HFLC_ECOLI). hflc and hflk govern the stability of phage lambda cii protein and have been proposed to encode or regulate a cii- specific protease. Pfam: SPFH domain/ Band 7 family signal peptide; Family membership
YP_932440.1	Conserved hypothetical membrane protein. Homology to NE1283 of Nitrosomonas europaea of 60% (trembl|Q82V27). No domains predicted. Signal peptide. 1 TMH; Conserved hypothetical protein
YP_932441.1	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
YP_932442.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_932443.1	Ribonuclease R (EC 3.1.-.-) (RNase R) (VacB protein homolog). 3-exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A) poly(U) and ribosomal RNAs. Similar to SWISSPROT: sprot|RNR_ECOLI (38% Escherichia coli, ribonuclease R; RNase R / VacB protein) InterPro: IPR004476 3_prime_RNase. IPR003029 RNA binding S1. Pfam: PF00773 RNB-like protein. TIGRFAM: TIGR00358 VacB and RNase II family 3'-5' exoribonucleases.; High confidence in function and specificity
YP_932444.1	Specificity unclear
YP_932445.1	Probable nitrate regulatory protein,; High confidence in function and specificity
YP_932446.1	Part of the ABC transporter complex NasFED involved in nitrate import. 59% Similar to the putative periplasmic-binding protein NasF in Klebsiella oxytoca. TREMBL:Q48466 InterPro:IPR010067; SsuA_fam.IPR006311; Tat. TIGRFAMs:TIGR01728; SsuA_fam; 1.TIGR01409; TAT_signal_seq; 1. Signal peptide present.; High confidence in function and specificity
YP_932447.1	Nitrate transport permease nasE. 41% Similar to the nitrate permease, nrtB in Synechococcus sp.Part of the ABC transporter complex nrtBCD involved in nitrate import.Probably responsible for the translocation of the substrate across the membrane. SWISSPROT:NRTB_SYNP7.P38044. InterPro:IPR000515; BPD_transp.IPR005889; NtrB. Pfam:PF00528; BPD_transp; 1. TIGRFAMs:TIGR01183; ntrB; 1. TMHelix: 4.; High confidence in function and specificity
YP_932448.1	Part of the ABC transporter complex nasFED involved in nitrate import. 64% Similar to the nitrate transport membrane protein, nasD in Klebsella oxytoca. Probably responsible for energy coupling to the transport system. SWISSPROT:NASD_KLEOX.P39459. InterPro:IPR003593; AAA_ATPase.IPR003439; ABC_transporter.IPR005890; NtrCD. Pfam:PF00005; ABC_tran; 1. TIGRFAMs:TIGR01184; ntrCD; 1.; High confidence in function and specificity
YP_932449.1	Uroporphyrin-III C-methyltransferase (EC 2.1.1.107) (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). CATALYZES BOTH METHYLATIONS AT C-2 AND C-7 OF UROGEN III LEADING TO PRECORRIN-1 AND PRECORRIN-2; THEIR OXIDATIVE ESTERIFICATION GIVES RESPECTIVELY FACTOR I OCTAMETHYL ESTER AND SIROHYDROCHLORIN (BY SIMILARITY). dph5: diphthine synthase; High confidence in function and specificity
YP_932450.1	Putative nitrate reducatse small subunit. Homology to nasC of K. oxytoca of 38% (trembl|Q48467). NasC probably mediates electron transfer from NADH to NasA, the nitrate reductase. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs; Family membership
YP_932451.1	Probable Nitrate reductase. Homology to nasA of K. oxytoca of 41% (sprot|NASA_KLEOX). Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants fungi and bacteria. InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain no signal peptide no TMH Helixturnhelix motif; High confidence in function and specificity
YP_932452.1	Putative methyl-accepting chemotaxis protein,; Specificity unclear
YP_932453.1	Conserved hypothetical secreted protein. Homology to Daro03002329 of Dechloromonas aromatica of 40% (gi|53730441|ref|ZP_00348795.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_932454.1	GGEF/EAL/PAS/PAC-domain containing protein
YP_932455.1	50%Cupin.IPR007113; Cupin_sup. Pfam:PF00190; Cupin; 1. 28%
YP_932456.1	Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I , otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- stranded DNA, followed by passage and rejoining of another single-stranded DNA region [4]. This reaction brings about the conversion of one topological isomer of DNA into another: e.g.,relaxation of superhelical turns; interconversion of simple and knotted rings of single-stranded DNA; and intertwisting of single-stranded rings of complementary sequences.; Family membership
YP_932457.1	Putative oxygen-insensitive NADPH nitroreductase. Homology to snrA of S. typhimurium of 37% (sprot|NFSA_SALTY) REDUCTION OF NITROAROMATIC COMPOUNDS USING NADH. REDUCES NITROFURAZONE BY A PING-PONG BI-BI MECHANISM POSSIBLY TO GENERATE A TWO-ELECTRON TRANSFER PRODUCT. MAJOR COMPONENT OF THE OXYGEN- INSENSITIVE NITROREDUCTASE ACTIVITY IN E.COLI. Pfam: Nitroreductase family no signal peptide no TMHs; Family membership
YP_932458.1	Probable flavodoxin. Homology to isiB of Synechococcus sp. of 45% (pir|B47673) Flavodoxins are electron-transfer proteins that function in various electron transport systems. Flavodoxins bind one FMN molecule, which serves as a redox-active prosthetic group and are functionally interchangeable with ferredoxins. Pfam: Flavodoxin no signal peptide no TMHs; High confidence in function and specificity
YP_932459.1	Putative GufA protein. 31% Zn_transpt_Zip.InterPro: ZIP Zinc transporter Pfam: PF02535; Zip; 1. TMHelix: 9. Signal peptide present.; Specificity unclear
YP_932460.1	catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge
YP_932461.1	DNA polymerase III subunit tau (EC 2.7.7.7) [Contains: DNA polymerase III subunit gamma]. The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA. InterPro: AAA-protein (ATPases associated with various cellular activities); High confidence in function and specificity
YP_932462.1	conserved hypothetical protein Pfam: Uncharacterized BCR, YbaB family
YP_932463.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_932464.1	Probable ubiquinol-cytochrome c reductase iron-sulfur protein (Rieske iron-sulfur protein) (RISP). Homology to petA of R. gelantinosus of 63% (trembl|Q93SY7). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. Pfam: Rieske [2Fe-2S] domain singal peptide no TMHs; High confidence in function and specificity
YP_932465.1	Ubiquinol-cytochrome c reductase cytochrome b protein. Homology to petB of R. gelatinosus of 72% (trembl|Q93SY6). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). Pfam: Cytochrome b (N-terminal)/b6/petB; cytochrome b (C-terminal)/b6/petD no signal peptide 10 TMHs; High confidence in function and specificity
YP_932466.1	Conserved hypothetical ubiquinol-cytochrome c reductase cytochrome c1 protein. Homology to petC of R. solanacearum of 52% (trembl|Q8XVA4). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c. InterPro: Cytochrome c1 (IPR002326) Pfam: Cytochrome_c1 signal peptide 1 TMH; Conserved hypothetical protein
YP_932467.1	Probable Stringent starvation protein A. Homology to sspA of E. coli of 43% (sprot|SSPA_ECOLI). FORMS AN EQUIMOLAR COMPLEX WITH THE RNA POLYMERASE HOLOENZYME (RNAP) BUT NOT WITH THE CORE ENZYME. IT IS SYNTHESIZED PREDOMINANTLY WHEN CELLS ARE EXPOSED TO AMINO ACID STARVATION AT WHICH TIME IT ACCOUNTS FOR OVER 50% OF THE TOTAL PROTEIN SYNTHESIZED. Pfam: Glutatione S-transferase,N-terminale domaine no TMHs; Family membership
YP_932468.1	Putative stringent starvation protein B. Homology to sspB of E. coli of 38% (sprot|SSPB_ECOLI) Seems to act in concert with sspA in the regulation of several proteins during exponential and stationary-phase growth. The exact function of sspB is not yet known. Pfam: Stringent starvation protein B no signal peptide no TMHs
YP_932469.1	InterPro: Glycosyl transferases group 1; Family membership
YP_932470.1	Hemerythrin-like protein, 49% Identity to SProt;Q8Y1B3. Has PF01814, Hemerythrin HHE cation binding domain; IPR002063, Hemerythrin; Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor P80255 binds Cadmium so as to protect the organism from toxicity . However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96 is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.
YP_932471.1	The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear
YP_932472.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
YP_932473.1	conserved hypothetical outer membrane protein. Homology to ne0930 of N. europaea of 44% (trembl|Q82VX0) Pfam: Bacterial surface protein signal peptide no TMHs; Family membership
YP_932474.1	Conserved hypothetical secreted protein. Homology to bb3356 of B. bronchiseptica of 83% (trembl|Q7WH54). Pfam: DUF534 This is a family of putative secreted proteins of unknown function. signal peptide no TMHs; Conserved hypothetical protein
YP_932475.1	Conserved hypothetical ABC transporter permease. PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851) Pfam: Branched-chain amino acid transport system/permease component no signal peptide 8 TMHs 2A78: Carboxylate/Amino Acid/Amine Tran; Specificity unclear
YP_932476.1	Thiamine transport ATP-binding protein thiQ. PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM TBPA-THIPQ FOR THIAMINE AND TPP. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q7WH56: 84% identity, 92% similarity Description:putative abc-transporter atp-binding component InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; ProDom PD000006; ABC_transporter; 1. SMART SM00382; AAA recf: DNA replication and repair protein NO transmembrane helices; Function unclear
YP_932477.1	Chaperonin GroES. Homolgy to groES of B. japonicum of 61% (sprot|CH11_BRAJA) Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. InterPro: Chaperonins cpn10 (10 Kd subunit)(IPR001476) Pfam: Chaperonin 10 kd subunit no signal peptide no TMH; High confidence in function and specificity
YP_932478.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_932479.1	Probable two-component response regulatory protein,Response_reg. IPR001867; Trans_reg_C. Pfam: PF00072; response_reg. PF00486; trans_reg_C. SMART: SM00448; REC.; Specificity unclear
YP_932480.1	Putative two-component system histidine kinase,; Specificity unclear
YP_932481.1	Conserved hypothetical membrane protein. Homology to XCC4058 of Xanthomonas campestris of 55% (trembl|Q8P3L3) Has PF04341, Protein of unknown function,DUF485; IPR007436;This family includes several putative integral membrane proteins. no signal peptide 1 TMH; Conserved hypothetical protein
YP_932482.1	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake
YP_932483.1	Probable transcriptional regulatory protein,Response_reg. IPR001867; Trans_reg_C. Pfam: PF00072; response_reg. PF00486; trans_reg_C. SMART: SM00448; REC. Transcriptional regulatory protein tctD. TRANSCRIPTIONAL ACTIVATOR OF THE TCTI TRICARBOXYLATE TRANSPORT SYSTEM OPERON.; Specificity unclear
YP_932484.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_932485.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_932486.1	Protein methyltransferase hemK (EC 2.1.1.-) (Protein-glutamine N- methyltransferase hemK) (Protein-(glutamine-N5) MTase hemK) (M.StyLTHemKP). Methylates the translation termination release factor RF1 on Gln-235 and RF2 on Gln-252.; Family membership
YP_932487.1	Conserved hypothetical protein. Homology to ne1911 of N. europaea of 67%. InterPro: Glutaredoxin-related protein (IPR004480) TIGR00365: glutaredoxin-related protein no signal peptide no TMHs
YP_932488.1	Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present.; Conserved hypothetical protein
YP_932489.1	Conserved hypothetical protein, 35% identity (56% similarity) to TrEMBL;Q82U70. Signal peptide Present. No TMH reported Present.
YP_932490.1	Hypothetical Protein. No Good functional or similar proteins matching in the database. No domains, repeats,motifs or features present.
YP_932491.1	Hypothetical protein predicted by Glimmer/Critica. No homology to data bank. no domains predicted. no signal peptide. no TMHs
YP_932492.1	Putative serine/threonine protein kinase,; Family membership
YP_932493.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_932494.1	Putative alginate biosynthesis protein AlgZ/FimS,; High confidence in function and specificity
YP_932495.1	Probable alginate biosynthesis regulatory protein AlgR,; High confidence in function and specificity
YP_932496.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
YP_932497.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_932498.1	Uroporphyrinogen-III synthase (Uroporphyrinogen-III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]). catalytic activity: hydroxymethylbilane = uroporphyrinogen-iii + h(2)o. pathway:porphyrin biosynthesis; fourth step. ribH: riboflavin synthase beta subunit; Specificity unclear
YP_932499.1	Putative uroporphyrin-III C-methyltransferase. catalytic activity: 2 s-adenosyl-l-methionine + uroporphyrin iii = 2 s-adenosyl-l-homocysteine + sirohydrochlorin. pathway: siroheme and cobalamin biosynthesis.; Specificity unclear
YP_932500.1	HemY protein. involved in a late step of protoheme ix synthesis.; High confidence in function and specificity
YP_932501.1	Glc operon transcriptional activator,; High confidence in function and specificity
YP_932502.1	Probable glycolate oxidase subunit glcD. Homology to glcD of E. coli of 64% (sprot|GLCD_ECOLI) InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; High confidence in function and specificity
YP_932503.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal pepitde. 1 TMH
YP_932504.1	Probable glycolate oxidase subunit GlcE. Homology to glcE of E. coli of 47% (sprot|GLCE_ECOLI) InterPro: FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain Tigrfam: glcD: glycolate oxidase subunit GlcD no singla peptide no TMHs; High confidence in function and specificity
YP_932505.1	Probable glycolate oxidase iron-sulfur subunit. Homology to glcF of E. coli of 56% (sprot|GLCF_ECOLI) Pfam: Domain of unknown function (DUF224) (192-256 aa; 329-391 aa) no signal peptide no TMHs; High confidence in function and specificity
YP_932506.1	Putative phosphoprotein phosphatase,; Conserved hypothetical protein
YP_932507.1	Probable NAD(P) transhydrogenase, subunit alpha part 1. Homology to pntAA of R. rubrum of 44% (sprot|PNAA_RHORU). The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. Tirfam: pntA: NAD(P) transhydrogenase alpha subunit Pfam: Alanine dehydrogenase/pyridine nucleotide dehydrogenase no signal peptide no TMHs; High confidence in function and specificity
YP_932508.1	Conserved hypothetical NAD(P) transhydrogenase,subunit alpha part 2. Homology to pntA of X. axonopodis of 74% (trembl|Q8PNW6). The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. 3 TMHs no signal peptide; High confidence in function and specificity
YP_932509.1	Probable NAD(P) transhydrogenase, subunit beta. Homology to pntB of R. rubrum of 46% (sprot|PNTB_RHORU) The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. Pfam: NAD(P) transhydrogenase beta subunit signal peptide 7 TMHs; High confidence in function and specificity
YP_932510.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_932511.1	Hypothetical signaling protein
YP_932512.1	Putative ATP-dependent RNA helicase rhlE.; Family membership
YP_932513.2	Conserved hypothetical protein. Homology to xcc0816 of X. campestris of 49% (trembl|Q8PCB8) Pfam: FtsJ-like methyltransferase no signal peptide no TMHs
YP_932514.1	Probable oxidoreductase Tas. Homology to tas of E. coli of 51% (sprot|TAS_ECOLI). InterPro: Aldo/keto reductase family (IPR001395) Pfam: Aldo/keto reductase family no signal peptide no TMHs; Function unclear
YP_932515.1	Conserved hypothetical secreted protein. Homology to Rgel02001790 of Rubrivivax gelatinosus of 45% (gi|47573892|ref|ZP_00243929.1|(NBCI ENTREZ)) . No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_932516.1	Glycerol-3-phosphate-binding periplasmic protein precursor. SN-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system ugpACE. 30% SBP_bac_1.IPR006061; SBP_dom1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present.; High confidence in function and specificity
YP_932517.1	hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate
YP_932518.1	Polyprenyl synthetase,82% identity to TrEMBL;Q5P1Y1. Has Pfam;PF00348, Polyprenyl synthetase.(IPR000092,Polyprenyl_synt)A variety of isoprenoid compounds are synthesized by various organisms. For example in eukaryotes the isoprenoid biosynthetic pathway is responsible for the synthesis of a variety of end products including cholesterol, dolichol, ubiquinone or coenzyme Q. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Among the enzymes that participate in that pathway, are a number of polyprenyl synthetase enzymes which catalyze a 1'4-condensation between 5 carbon isoprene units. It has been shown that all the above enzymes share some regions of sequence similarity. Two of these regions are rich in aspartic-acid residues and could be involved in the catalytic mechanism and/or the binding of the substrates.; High confidence in function and specificity
YP_932519.1	Probable transcriptional regulator, LysR family,; Family membership
YP_932520.1	L-lactate dehydrogenase. Homology to lldA of N. meningitidis of 72% (trembl|Q51135). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Proteins binding FMN and related compounds core region (IPR003009 Pfam: FMN-dependent dehydrogenase no signal peptide no TMHs; High confidence in function and specificity
YP_932521.1	probable competence lipoprotein comL precursor. Homology to comL of N. gonorrhoeae of 47% (sprot|COML_NEIGO(SRS)) REQUIRED FOR EFFICIENT TRANSFORMATION OF NEISSERIA MENINGITIDIS BY SPECIES-RELATED DNA (By similarity). InterPro: TPR repeat (IPR001440) no signal peptide no TMH ccoS: cytochrome oxidase maturation pro; High confidence in function and specificity
YP_932522.1	Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil at positions 1911 1915 and 1917 in 23S ribosomal RNA.; Family membership
YP_932523.1	Conserved hypothetical protein. Homology to CV2191 of C.violaceum of 64% (tremble:Q7NVZ9). Has PF02578,Uncharacterised ACR, YfiH family COG1496. InterPro;IPR003730. No signal peptide. No TMHs. TIGR00726: conserved hypothetical protein
YP_932524.1	Conserved hypothetical membrane protein. Homology to RS03993 of R.solanacearum of 48% (trembl|Q8XYX6(SRS)). No domains. No signal peptide. 1 TMH; Conserved hypothetical protein
YP_932525.1	Entry name :- TREMBL:Q9ZB54 Prim. accession # Q9ZB54 Identities = 290/560 (51%) InterPro:- IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam:- PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Prediction: Signal peptide Signal peptide probability: 0.999 Number of predicted TMHs: 0; Family membership
YP_932526.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (60% identity); TREMBL:Q8XYX3 (59% identity). Pfam (PF00106): Short chain dehydrogenase.; High confidence in function and specificity
YP_932527.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (62% identity); TREMBL:Q8XYX3 (62% identiy). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase. SignalP reporting signal peptide.; High confidence in function and specificity
YP_932528.1	phbF protein, 57% identity to TrEMBL;Q7NYA7. Has 2 copies of PF05233, PHB accumulation regulatory domain;IPR007897, PHB_accumulat: The proteins this domain is found in are typically involved in regulating polymer accumulation in bacteria, particularly poly-beta-hydroxybutyrate (PHB); High confidence in function and specificity
YP_932529.1	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit
YP_932530.1	Hypothetical protein ychK. TREMBL:Q89IT4: 42% identity, 58% similarity InterPro: Uncharacterized protein family UPF0028 InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin hypA: hydrogenase expression/formation Non-secretory protein with signalpeptide probability:0.141 (SignalP predicted) Absence of TMH's; Family membership
YP_932531.1	Putative glycolate oxidase subunit GlcD. Homology to glcD of E. coli of 32% (sprot|GLCD_ECOLI). InterPro: FAD linked oxidase C-terminal (IPR004113);m FAD linked oxidas, N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership
YP_932532.1	converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA
YP_932533.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_932534.1	Thioredoxin-disulfide reductase. Homology to trxA of T. ferrooxidans of 69% (THIO_THIFE). Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide. InterPro: Thioredoxin (IPR006662) Pfam: Thioredoxin no signal peptide no TMHs; Specificity unclear
YP_932535.1	Probable ferredoxin. Homology to fdxA of A. vineladii of 66% (sprot|FER1_AZOVI(SRS)). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN COULD PLAY A ROLE IN REGULATING GENE EXPRESSION BY INTERACTING DIRECTLY WITH DNA. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain IPR001450); 7Fe ferredoxin (IPR000813) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_932536.1	TREMBL:Q8XZ43; 52% identity, 70% similarity. TREMBL:Q8F5Y8; 30% identity, 56% similarity. Protein At5g10860 mitochondrial precursor. IPR000644: CBS domain Pfam:PF00571 - GARS_N TIGRFAM: rrf2 family, KpsF/GutQ family (by similarity) kpsF: KpsF/GutQ family protein; Specificity unclear
YP_932537.1	Esterification concomitant with transport of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q7NY16 (61% identity); TREMBL:Q7WLG0 (63% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase Pfam (PF00501): AMP-binding enzyme.; High confidence in function and specificity
YP_932538.1	Acetolactate synthase isozyme I large subunit (AHAS-I) (Acetohydroxy-acid synthase I large subunit) (ALS-I). InterPro: Acetolactate synthase large subunit biosynthetic type acolac_lg: acetolactate synthase large subunit,biosynthetic type; High confidence in function and specificity
YP_932539.1	with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit
YP_932540.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_932541.1	Putative transport protein. Similarity to sugar transporters (lacY): lactose permease 2A0105.Similar to POT family of proteins with DUF domains and 12 transmembrane helices. 31% identity and 47% similarity to putative MFS metabolite transporter from Pseudomonas aeruginosa PA01; Family membership
YP_932542.1	Conserved hypothetical secreted protein. Homology to bb2112 of B. bronchiseptica of 55% (trembl|Q7WKJ4). Pfam: Peptidase family M48 signal peptide no TMHs; Conserved hypothetical protein
YP_932543.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_932544.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_932545.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_932546.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_932547.1	In Pseudomonas aeruginosa, FimV ist probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (28%). Pfam (PF01476): LysM domain Pfam (PF04102): SlyX, may be a coiled-coil structure SignalP reporting Signal peptide; Function unclear
YP_932548.1	Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership
YP_932549.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_932550.1	catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis
YP_932551.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_932552.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_932553.1	Function:-THIS PROTEIN IS A COMPONENT OF THE ACETYL COENZYME A CARBOXYLASE COMPLEX; FIRST BIOTIN CARBOXYLASE CATALYZES THE CARBOXYLATION OF THE CARRIER PROTEIN AND THEN THE TRANSCARBOXYLASE TRANSFERS THE CARBOXYL GROUP TO FORM MALONYL-COA (BY SIMILARITY). Entry name :-SWISSPROT:ACCD_ECOLI Prim. accession # P08193 Identities = 178/287 (62%) InterPro:- IPR000438; ACoACC_transB. IPR000022; Carboxyl_trans. Pfam:- PF01039; Carboxyl_trans; 1. Signal peptide probability: 0.000 Number of predicted TMHs: 0; High confidence in function and specificity
YP_932554.1	FolC bifunctional protein [Includes: Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS); Dihydrofolate synthase (EC 6.3.2.12)]. Conversion of folates to polyglutamate derivatives.; High confidence in function and specificity
YP_932555.1	Conserved hypothetical membrane proteine. Homology to BB2598 of Bordetella bronchiseptica of 37% (trembl|Q7WJA1(SRS)). Has 2 copies of PF05036, Sporulation related repeat;IPR007730, SPOR; This 35 residue repeat is found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This repeat might be involved in binding peptidoglycan (Bateman A pers obs). FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localises to the septum ring complex. The CwlM gene is a cell wall hydrolase so this repeat may help localise the protein to the cell wall. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_932556.1	Colicin V production protein (dedE protein) (Pur regulon 18 kDa protein). REQUIRED FOR COLICIN V PRODUCTION FROM PLASMID INCFI COLV3-K30. TREMBL:Q82WH7: 29% identity,38% similarity InterPro:IPR003825; Colicin_V. Pfam:PF02674; Colicin_V TIGR00304: conserved hypothetical protei Signal peptide present (Signal P predicted) TMH's 4 (TMHMM predicted); High confidence in function and specificity
YP_932557.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_932558.1	catalyzes the conversion of O-succinylhomoserine into homocysteine
YP_932559.1	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine
YP_932560.1	Peptidyl-prolyl cis-trans isomerase B. Homology to ppiB of E.coli of 71% (sprot|PPIB_ECOLI). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: Cyclophilin-type peptidyl-prolyl cis-trans isomerase(IPR002130) Pfam: Cyclophilin-type peptidyl-prolyl cis-trans isomerase no signal peptide no TMH; High confidence in function and specificity
YP_932561.1	Probable peptidyl-prolyl cis-trans isomerase. Homology to ppiA of E. coli of 56% (SWISSPROT:PPIA_ECOLI) PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: Cyclophilin-type peptidyl-prolyl cis-trans isomerase (IPR002130) Pfam: Cyclophilin-type peptidyl-prolyl cis-trans isomerase Signal peptide no TMHs; High confidence in function and specificity
YP_932562.1	Conserved hypothetical secreted proteins. Homology to of Dechloromonas aromatica of 56% (gi|41723709|ref|ZP_00150619.1|(NBCI ENTREZ)). Signal Peptide Present. No TMH present. Has PF03734:(IPR005490)ErfK/YbiS/YcfS/YnhG;This family of proteins are found in a range of bacteria. The conserved region contains a conserved histidine and cysteine,suggesting that these proteins have an enzymatic activity. Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate.; Conserved hypothetical protein
YP_932563.1	Conserved hypothetical secreted protein. Homology to Daro03002816 of Dechloromonas aromatica of 42% (gi|53730051|ref|ZP_00348646.1|(NBCI ENTREZ)). domain structure: 59 aa - 92 aa TRP; 93 aa- 126 aa TRP; 127 aa -155 aa TRP. InterPro: TPR repeat (IPR001440); Type I antifreeze protein (IPR000104). Pfam: TRP Domain. signal peptide. no TMHs; Conserved hypothetical protein
YP_932564.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_932565.1	This family includes extracellular ligand binding domains of a wide range of receptors and it also includes the bacterial amino acid binding proteins of known structure. Similar to trembl|Q8XQ39 (40%) and to trembl|Q89G00 (32%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Family membership
YP_932566.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_932567.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_932568.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_932569.1	Conserved hypothetical protein. Homology to an orf of Polaromonas sp. JS666 of 43% ( ZP_00361754). No domains predicted. No singal peptide. No TMHs
YP_932570.1	negatively supercoils closed circular double-stranded DNA
YP_932571.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_932572.1	Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity
YP_932573.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_932574.1	Prephenate dehydrogenases are involved in tyrosine biosynthesis. Similar to trembl|Q7NSL5 (54%) and to trembl|Q82XD9 (47%). Pfam: PDH, Prephenate dehydrogenase. TMHMM reporting one Tmhelix. SignalP reporting Signal peptide.; Specificity unclear
YP_932575.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; catalyzes CMP phosphorylation
YP_932576.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_932577.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_932578.1	38% identity with Hypothetical protein from Chromobacterium violaceum TrEMBL:Q7NTL0,Genename CV3044 Signal Peptide present TMHMM reporting for transmembrane helices:2 present.; Conserved hypothetical protein
YP_932579.1	Putative N-acetylglucosaminyl transferase. Enzyme that is involved in the catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol. 36% Cas_TM1810_C.IPR001574; RIP.IPR001440; TPR.IPR008941; TPR-like.InterPro: TPR repeat TIGRFAMs:TIGR01870; cas_TM1810; 1. TMHx:1; Specificity unclear
YP_932580.1	UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).; High confidence in function and specificity
YP_932581.1	catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide
YP_932582.1	Probable DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A). TIGR00099: conserved hypothetical protein.; Function unclear
YP_932583.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_932584.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_932585.1	50S ribosomal protein L35.; Family membership
YP_932586.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_932587.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_932588.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_932589.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_932590.1	Putative MerR-family transcriptional regulator,similar toTREMBL: trembl|Q83C17 (51% Coxiella burnetii,cbu1319) Pfam: PF00376 MerR family regulatory protein. HTH reporting nucleic acid binding motif.
YP_932591.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_932592.1	Protein-L-isoaspartate O-methyltransferase, 56% Identity to TrEMBL;Q7VXN1.51% Identity to TrEMBL;Q82VW0,Q7NRV0. SProt;Q886L4(52% Idnetity), Q87LQ6(51%),P24206(47%) Has PF01135, Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);IPR000682, PCMT; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MEDLINE: (which is also known as L-isoaspartyl protein carboxyl methyltransferase) is an enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to the free carboxyl groups of D-aspartyl or L-isoaspartyl residues in a variety of peptides and proteins. The enzyme does not act on normal L-aspartyl residues L-isoaspartyl and D-aspartyl are the products of the spontaneous deamidation and/or isomerization of normal L-aspartyl and L- asparaginyl residues in proteins. PCMT plays a role in the repair and/or degradation of these damaged proteins; the enzymatic methyl esterification of the abnormal residues can lead to their conversion to normal L-aspartyl residues.
YP_932593.1	Conserved hypothetical lipoprotein. Homology to nlpD of R. gelatinosus of 43% (trembl|Q9JP90) InterPro: Peptidase family M23/M37 (IPR002886); LysM motif (IPR002482) Pfam: LysM domain; Peptidase family m23/M27 signal peptide no TMHs; Conserved hypothetical protein
YP_932594.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses
YP_932595.1	Putative membrane-bound lytic murein transglycosylase. homology to mltb of E. coli of 38% (sprot|MLTB_ECOLI) Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. no domains prediced signal peptide no TMHs; Family membership
YP_932596.1	Conserved hypotetical membrane protein. Homology to RSp0111 of R. solanacearum of 41% (trembl|Q8XTJ7(SRS)) Pfam: Transglutaminase-like superfamily signal peptide probable 4 TMHs; Conserved hypothetical protein
YP_932597.1	Conserved hypothetical membrane protein. Homology to RS03012 of Ralstonia solanacearum of 40% (trembl|Q8XTJ8) InterPro: Protein of unknown function DUF58 This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterterPro: IPR002881; DUF58. Pfam: PF01882; DUF58; Non-secretory with low signal peptide probability (Signal P predicted). TMHMM predicted 2 transmembrane helices.; Conserved hypothetical protein
YP_932598.1	MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBL:Q883V0: 60% identity, 73% similarity SMART: SM00382; AAA InterPro: IPR003593; AAA_ATPase. IPR001270; Chaprnin_clpA/B. IPR003442; UPF0079. Pfam: PF02367; UPF0079; Pfam: Mg_chelatase:Magnesium chelatase, subunit ChlI ruvB: Holliday junction DNA helicase Ru No signal peptide and transmembrane helices; High confidence in function and specificity
YP_932599.1	Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are all members of an ancient protein superfamily, TREMBL:Q7VZF1 (58% identity); TREMBL:Q7NRU4 (57% identity). InterPro (IPR000286): Histone deacetylase family Pfam (PF00850): Histone deacetylase domain.; Family membership
YP_932600.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_932601.1	Putative lipoprotein. Homology to nlpB of E. coli of 20% (sprot|NLPB_ECOLI) This family consists of a number of bacterial lipoproteins often known as NlpB or DapX. This lipoprotein is detected in outer membrane vesicles in Escherichia coli and appears to be nonessential. Pfam: NlpB/DapX lipoprotein singal peptide no TMHs; Family membership
YP_932602.1	Conserved hypothetical secreted protein. Homology to NMB1523 of N.meningitidis of 50% (tremble:Q9JYL7) No domains predicted. No TMHs Signal Peptide present.; Conserved hypothetical protein
YP_932603.1	Conserved hypothetical protein. Homology to CV3581 of C.violaceum of 48% (tremble:Q7NS46) SM00558;JmjC:Probable enzymes, but of unknown functions,that regulate chromatin reorganisation processes. No signal peptide or TMH present. lytR_cpsA_psr: cell envelope-related fu
YP_932604.1	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]
YP_932605.1	Ribosomal large subunit pseudouridine synthase E (EC 4.2.1.70) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA; Family membership
YP_932606.1	Conserved hypothetical secreted protein. Homology to rsc2494 of R. solanacearum of 48% (trembl|Q8XWI0(SRS)). Pfam: DUF192 signal peptide no TMHs; Conserved hypothetical protein
YP_932607.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
YP_932608.1	membrane protein involved in the flagellar export apparatus
YP_932609.1	positive regulator of class III flagellar genes
YP_932610.1	Hypothetical flagellar related protein FleN. Homology to fleN of Pseudomonas fluorescens of 27% (AAN03366). No domains predicted. No signal peptide. No TMHs
YP_932611.1	RNA polymerase sigma factor for flagellar operon (Sigma-F factor) (Sigma-27) (Sigma-28). THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. THIS ALTERNATIVE SIGMA FACTOR IS SPECIFIC FOR CLASS 3 FLAGELLAR OPERONS. Similar to SWISSPROT: sprot|FLIA_PSEAE (46% Pseudomonas aeruginosa, RNA polymerase sigma factor for flagellar operon (sigma-f factor) (sigma-28)). InterPro: IPR000943 Sigma_70. Pfam: PF00140 Sigma-70 factor, region 1.2. HTH reporting nucleic acid binding motif. gatB_rel: aspartyl-tRNA(Asn) amidotrans; High confidence in function and specificity
YP_932612.1	homologous to MotA; this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; these organisms have both MotA and MotC
YP_932613.1	E. coli uses five MCP-family receptors to promote chemotactic movements toward different attractant compounds: Tar is the aspartate and maltose chemoreceptor. Methyl-accepting chemotaxis protein,; Specificity unclear
YP_932614.1	Homologous to MotB. These organism have both MotB and MotD. With MotC (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. Either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility
YP_932615.1	DcrH:hemerythrin protein, is transmembrane methyl-accepting protein probably involved in bacterial chemotaxis . 31% Hemerythrin. Pfam:PF01814; Hemerythrin; 1.; High confidence in function and specificity
YP_932616.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_932617.1	Conserved hypothetical protein. Homology to Bucepa03000705 of Burkholderia cepacia of 33% (gi|46323973|ref|ZP_00224335.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_932618.1	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. Enzyme that hydrolyzes not only oxygen-phosphorus bonds in inorganic pyrophosphate but also nitrogen-phosphorus bonds in phospholysine,phosphohistidine and imidodiphosphate in vitro. 38% HAD_SF_IIA.IPR006355; HAD_SF_IIA_hyp2.IPR005834; Hydrolase. Pfam:PF00702;Hydrolase; 1. TIGRFAMs:TIGR01460; HAD-SF-IIA; 1.TIGR01458; HAD-SF-IIA-hyp3; 1. TMHelix:1; High confidence in function and specificity
YP_932619.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_932620.1	Conserved hypothetical membrane protein,TrEMBL;Q8NSJ9(49% identity,73% similarity),TrEMBL;Q7VSN7(53% identity, 72% similarity). Has 2 PF03458(IPR005115 ):UPF0126 domain;Domain always found as pair in bacterial membrane proteins of unknown function. This domain contains three transmembrane helices. The conserved glycines are suggestive of an ion channel (C. Yeats unpublished obs.). signal peptide 6 TMHs; Conserved hypothetical protein
YP_932621.1	Isocitrate lyase. Homology to aceA of E. coli of 73% (sprot|ACEA_ECOLI). Isocitrate lyase is an enzyme that catalyzes the conversion of isocitrate to succinate and glyoxylate. This is the first step in the glyoxylate bypass, an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants. InterPro: Isocitrate lyase (IPR000918) Pfam: Isocitrate lyase family no signal peptide no TMHs; High confidence in function and specificity
YP_932622.1	Putative AraC-family transcriptional regulator,; Family membership
YP_932623.1	Phytoene dehydrogenase (EC 1.14.99.-) (Phytoene desaturase). Phytoene dehydrogenase (phytoene desaturase) is an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene, TREMBL:Q8XYC4 (50% identity); SWISSPROT:P06108 (26% identity). InterPro (IPR008150): Bacterial-type phytoene dehydrogenase Pfam (Phytoene_dh): Phytoene dehydrogenase related enzyme.; High confidence in function and specificity
YP_932624.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8XYC0 (36% identity); TREMBL:Q9EX74 (34% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_932625.1	This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoatesynthase catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, TREMBL:Q9HZE2 (34% identity); TREMBL:Q8XSM9 (39% identity). Pfam (PF00857): Isochorismatase family.; Family membership
YP_932626.1	Ring hydroxylating dioxygenases are multicomponent 1,2-dioxygenase complexes that convert closed-ring structures to non-aromatic cis-diols. The beta subunit is may be responsible for the substrate specificity of the enzyme. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBa. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyY: Benzene 12-dioxygenase beta subunit (EC 1.14.12.3), involved in benzoate degradation.Degradation of benzoate to 2-hydro-12-dihydroxybenzoate (dhb).; Conserved hypothetical protein
YP_932627.1	Ring hydroxylating dioxygenases are multicomponent 1,2-dioxygenase complexes that convert closed-ring structures to non-aromatic cis-diols. Hydroxylase large component of 1,2-dioxygenase complex, involved in aromatic compounds degradation. 81% simialr to a Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBb. Involved in the aerobic degradation of carbazole by Pseudomonas resinovorans sp. strain CA10. TREMBL:Q8GI28 InterPro:IPR005806; Rieske_reg.IPR001663; Ring_hydroxyl_A. Pfam:PF00355; Rieske; 1. PF00848; Ring_hydroxyl_A; 1.; High confidence in function and specificity
YP_932628.1	Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 40% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. InterPro: NADH:cytochrome b5 reductase (CBR)(IPR001834); Ferredoxin (IPR001041); Oxidoreductase FAD and NAD(P) binding domain (IPR001433) Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership
YP_932629.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W060 (64%) and to sprot|LIVH_ECOLI (24%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting eight Tmhelix.; Specificity unclear
YP_932630.1	Putative branched-chain amino acid transport permease Homology to livM of S. typhimurium of 28%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system signal peptide probable 9 TMHs; Specificity unclear
YP_932631.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP binding domains are responsible for coupling the energy of ATP hydrolysis to conformational changes in the ransmembrane domains. Similar to trembl|Q7W058 (49%) and to sprot|LIVG_ECOLI (39%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily; Specificity unclear
YP_932632.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7W057 (65%) and to trembl|Q84HI4 (49%). Smart (SM00382): ATPase superfamily Pfam (PF00005): ABC transporter ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear
YP_932633.1	ABC transporter substrate binding proteins counts to the family of extracellular ligand binding proteins. It is a component of the high affinity amino acid transport system. Similar to trembl|Q83V39 (51%) and to trembl|Q7WF58 (49%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Function unclear
YP_932634.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
YP_932635.1	Conserved hypothetical protein. Homology to Daro03001685 of Dechloromonas aromatica of 46% (gi|41725028|ref|ZP_00151838.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_932636.1	ATP-dependent Clp protease ATP-binding subunit clpA. Homology to clpA of E. coli of 63% (sprot|CLPA_ECOLI). ATP-dependent specificity component of the clpP protease. It directs the protease to specific substrates. The primary function of the clpA-clpP complex appears to be the degradation of unfolded or abnormal proteins. InterPro: AAA-protein (ATPases associated with various cellular activities)(IPR003959); AAA ATPase superfamily (IPR003593); Clp amino terminus (IPR004176); chaperonins clpA/B (IPR001270); Bacterial typeII secretion system protein E (IPR001482) Pfam: Clp amino ternimal domain; ATPase family associated with cellular activites no signal peptide no TMHs; High confidence in function and specificity
YP_932637.1	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA
YP_932638.1	Cold-shock protein cspE, (When Escherichia coli is exposed to a temperature drop from 37 to 10 degrees centigrade, a 4-5 hour lag phase occurs, after which growth is resumed at a reduced rate. During the lag phase,the expression of around 13 proteins, which contain specific DNA-binding regions, is increased 2-10 fold. These so-called 'cold shock' proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature.); High confidence in function and specificity
YP_932639.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_932640.1	required for 70S ribosome assembly
YP_932641.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_932642.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_932643.1	catalyzes the formation of dUMP from dUTP
YP_932644.1	Conserved hypothetical MutT family protein. Homology to AGR_C_3368 of Agrobacterium tumefaciens of 33% (tremble:Q7CYF2). Pfam: NUDIX domain MutT is a small bacterial protein (~12-15Kd) involved in the GO system MEDLINE:1328155 responsible for removing an oxidatively damaged form of guanine (8-hydroxy- guanine or 7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with near equal efficiency, leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate, with the concomitant release of pyrophosphate. A short conserved N-terminal region of mutT (designated the MutT domain) is also found in a variety of other prokaryotic, viral and eukaryotic proteins. No signal peptide. No TMH; Family membership
YP_932645.1	Probable sulfide dehydrogenase, falvoprotein subunit (Flavocytochrome C flavoprotein subunit). Homology to fccB of C. vinosum of 40% (sprot|DHSU_CHRVI). Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; Family membership
YP_932646.1	Putative sulfide dehydrogenase, cytochrome subunit. Homology to fccA of C. limicola of 26% (sprot|CYSD_CHLLT(SRS)) InterPro: Cytochrome c class I (IPR003088); cytochrome c class IC (IPR008168) Pfam: Cytochrome C signal peptide no TMHs
YP_932648.1	Gene Function; High confidence in function and specificity
YP_932649.1	catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol
YP_932650.1	Isocitrate dehydrogenase [NADP]. Homology to icd2 of A. eutrophus of 80% (trembl|Q8KLU4) This monomeric type of isocitrate dehydrogenase is NADP-specific. It is an important enzyme of the TCA. Interpro: Isocitrate dehydrogenase NADP-dependent, monomeric type (IPR004436) Tigrfam: monomer-idh: isocitrate dehydrogenase NADP-dependent no singal peptide no TMHs; High confidence in function and specificity
YP_932651.1	Isocitrate dehydrogenase [NADP]. Homology to icd1 of A. eutropus of 75% (trembl|Q8KLU5) Isocitrate dehydrogenase is an important enzyme of the TCA which catalyzes the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+ Pfam: Isocitrate/isopropylmalate dehydrogenase Tigrfam: prok_nadp_idh: isocitrate dehydrogenase no signal peptide no TMHs; High confidence in function and specificity
YP_932652.1	Conserved hypothetical membrane protein. Homology to ws0602 of W. succinogenes of 63% (trembl|Q7MSB5(SRS)) no domains predicted no singal peptide 2 TMHs; Conserved hypothetical protein
YP_932653.1	Conserved hypothetical sodium:solute symporter. Homology to to ws0601 of W. succinogenes of 68% (trembl|Q7M9X9). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. InterPro: Sodium:solute symporter family (IPR001734) Tigrfam: sss: SSS sodium solute transporter superfamily no signal peptide 12 TMHs; Family membership
YP_932654.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No singal peptide 3 TMHs
YP_932655.1	Conserved hypothetical membrane protein. Homology to vv11244 of V. vulnificus of 42% (trembl|Q8DCZ3(SRS)) no domains predicted no signal peptide 2 TMHs; Conserved hypothetical protein
YP_932656.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_932657.1	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 61%; Function unclear
YP_932658.1	Conserved hypothetical membrane protein. Homology to rsc2670 of R. solanacearum of 64% (tremble: Q8XWO5) Pfam: LrgB-like family The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance. no signal peptide 6 TMHs; Conserved hypothetical protein
YP_932659.1	Conserved hypothetical membrane protein. This family is uncharacterised. It contains the protein LrgA that has been hypothesised to export murein hydrolases TREMBL:Q8XW06: 56% identity, 73% similarity InterPro:IPR005538; LrgA. Pfam: PF03788; LrgA; 1. ProDom: PD009239; LrgA Signal peptide present (Signal P predicted) TMH's 3 (TMHMM predicted); Conserved hypothetical protein
YP_932660.1	Conserved hypothetical membrane protein. Homology to Daro03002578 of Dechloromonas aromatica of 75% (gi|41723981|ref|ZP_00150871.1|(NBCI ENTREZ)). Has PF07670, Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for determining nucleoside specificity in the human CNT1 and CNT2 proteins. In the FeoB proteins, which are believed to be Fe2+ transporters, it includes the membrane pore region, so the function of this region is likely to be more general than just nucleoside specificity. This family may represent the pore and gate, with a wide potential range of specificity. Hence its name 'Gate'. no signal peptide. 2 TMHs; Conserved hypothetical protein
YP_932661.1	Hypothetical secreted protein. Signal Peptide present. No good homolgous hits in the PDB. No TMHs No domains predicted.
YP_932662.1	TREMBL:Q9HWH9: 45% identity, 52% similarity 2-nitropropane dioxygenase (EC 1.13.11.32) (Nitroalkane oxidase) (2-NPD). CATALYZES THE OXYGENATIVE DENITRIFICATION OF VARIOUS ANIONIC NITROALKANES. InterPro: 2-nitropropane dioxygenase InterPro:IPR004136; 2nprop_dioxygen. IPR003009; FMN_enzyme. Pfam PF03060; NPD thiE: thiamine-phosphate pyrophosphoryl No transmembrane helices (TMHMM predicted); High confidence in function and specificity
YP_932663.1	Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle
YP_932664.1	Conserved hypothetical membrane protein. Homology to mlr4286 of M. loti of 43% (trembl|Q98EE2) InterPro: IPR002781; DUF81.This domain is found in integral membrane proteins of prokaryotes which are uncharacterized Pfam:PF01925; DUF81 Signal peptide present and presence of 6 transmembrane helices; Conserved hypothetical protein
YP_932665.1	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 29% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear
YP_932666.1	Putative hydroxypyruvate reductase. Degrades an unidentified toxic product from the first step of tartrate degradation. Involved in the second step of the tartrate degradation pathway. 59% MOFRL.IPR005346; UPF0125. Pfam:PF05161; MOFRL; 1.PF03658; UPF0125; 1. Signal peptide present.; High confidence in function and specificity
YP_932667.1	Hydroxypyruvate isomerase (EC 5.3.1.22).Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).Belongs to the hyi family. 52%; High confidence in function and specificity
YP_932668.1	Conserved hypothetical protein. Homology to ORF153 of Rubrivivax gelatinosus of 48% (gi|55832787|gb|AAV66902.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_932669.1	L-lactate permease. Homology to lctP of E. coli of 72% (sprot|LLDP_ECOLI) Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force (By similarity). Tigrfam: lctP: L-lactate transport Pfam: L-lactate permease signal peptide 12 TMHs; High confidence in function and specificity
YP_932670.1	Conserved hypothetical iron-sulfur binding oxidase. Homology to pa4772 of P. aeruginosa of 53% (pir|H83050) InterPro: FAD linked oxidase C-terminal (IPR004413) Pfam: FAD binding domain ; Fad linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership
YP_932671.1	Conserved hypothetical iron-sulfur protein. Homology to cv3028 of C. violaceum of 68% (trembl|Q7NTM6) Tigrfam: TIGR00273: iron-sulfur cluster binding protein Pfam: 4Fe-4S binding domain no TMHs no signal peptide; Conserved hypothetical protein
YP_932672.1	Conserved hypothetical protein. Homology to DVU1781 of D.vulgaris of 45% (tremble:Q72B57). Has PF02589 DUF162 domain:Uncharacterized ACR, YkgG family. No signal peptide or TMH reported present.
YP_932673.1	Conserved hypothetical protein. Homologyt to nma1648 of N. meiningitidis of 55% (trembl|Q825P5) InterPro: Domain of unknown function DUF224 (IPR004017) Pfam: Domain of unknown function no signal no TMHS
YP_932674.1	Putative L-lactate dehydrogenase operon regulatory protein,; High confidence in function and specificity
YP_932675.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide. no TMH
YP_932676.1	Conserved hypothetical protein. Homology to the N-terminus of NE0717 of Nitrosomonas europaea of 56% (tremble:Q82WG3). Pfam: Cold shock protein domain RNA-binding domain that functions as a RNA-chaperone in bacteria and is involved in regulating translation in eukaryotes. Contains sub-family of RNA-binding domains in the Rho transcription termination factor. No signal peptide. No TMHs
YP_932677.1	Conserved hypothetical membrane protein. Homology to the C-terminus of ne0717 of N. europaea of 57% (trembl|Q82WG3). Pfam: Protein of unknown function (DUF1294). No signal peptide. 3 TMHs; Conserved hypothetical protein
YP_932678.1	Hypothetical protein. No homology to the data bank. No domains predicted. No signal peptide. No TMHs
YP_932679.1	Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4). 76% EGF_like.IPR001327; FAD_pyr_redox. IPR007419;Fer2_BFD.IPR006066; Nir_Si.IPR006067; Nir_Sir_4Fe4S. IPR005117; NiR_SiR_beta_fer. IPR001100; Pyr_redox. Pfam: PF04324; Fer2_BFD; 1.PF01077; NIR_SIR; 1.PF03460; NIR_SIR_ferr; 1. PF00070; Pyr_redox; 1. In E.coli, the NADH-dependent nitrite reductase catalyzes the six-electron reduction of nitrite to ammonia and also catalyzes the two-electron reduction of hydroxylamine to ammonia. The enzyme is a FAD-flavoprotein, and also contains a siroheme and one 2Fe-2S center.; High confidence in function and specificity
YP_932680.1	Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4). REQUIRED FOR ACTIVITY OF THE REDUCTASE. 66% simialr to the nirD protein from R. solanacearum,a probable nitrite reductase NADPH (small subunit) oxidoreductase [EC:1.7.1.4]. TREMBL:Q8XQK3. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit In E.coli, the NADH-dependent nitrite reductase catalyzes the six-electron reduction of nitrite to ammonia and also catalyzes the two-electron reduction of hydroxylamine to ammonia. The enzyme is a FAD-flavoprotein, and also contains a siroheme and one 2Fe-2S center.; Conserved hypothetical protein
YP_932681.1	76% For/Nit_transpt. Pfam: PF01226; Form_Nir_trans; 1. In E. coli, NirC is a putative nitrite transporter which is a member of the FNT family of formate and nitrite transporters. The nirC gene is located in the nir operon which codes for a NADH-dependent nitrite reductase. NirC may function to import nitrite as a substrate for this enzyme complex. The nir operon is anaerobically expressed and is repressed by oxygen. TMhelix:6; High confidence in function and specificity
YP_932682.1	Putative serin/threonin protein kinase,; Family membership
YP_932683.1	High confidence in function and specificity
YP_932684.1	catalyzes the formation of S-ureidoglycolate and urea from allantoate
YP_932685.1	Polysaccharide deacetylase family protein.This family of polysaccharide deacetylases includes NodB(nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase.It also includes chitin deacetylase from yeast,and endoxylanases which hydrolyses glucosidic bonds in xylan. 62% Polysac_deacet. Pfam:PF01522; Polysacc_deac_1. TIGR:PP4286.; Function unclear
YP_932686.1	Conserved hypothetical protein. Homology to RS01483 of R.solanacearum of 55% (tremble:Q8XXJ2). No domains predicted. No TMHs. No signal peptide.
YP_932687.1	Conserved hypothetical membrane protein. Homology to RS01489 of Ralstonia solanacearum of 50% (trembl|Q8XXJ8(SRS)) Has PF06181:Protein of unknown function (DUF989);This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide 8 TMHs; Conserved hypothetical protein
YP_932688.1	Conserved hypothetical transthyretin. Homology to pa1518 of P. aeruniosa of 62% (sprot|YF18_PSEAE) InterPro: Transthyretin precursor (IPR000895) Pfam: Transthyretin precursor no signal peptide no TMHs; Conserved hypothetical protein
YP_932689.1	TREMBL:Q8PC98: 42% identity, 54% similarity. Proline iminopeptidase (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP). SPECIFICALLY CATALYZES THE REMOVAL OF N-TERMINAL PROLINE RESIDUES FROM PEPTIDES (BY SIMILARITY). InterPro:IPR000073; A/b_hydrolase. IPR003089; AB_hydrolase. IPR002410; Peptidase_S33. IPR005944; Pept_S33. IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; TIGRFAMs: TIGR01249; pro_imino_pep_1 TIGR00149: conserved hypothetical protein; Specificity unclear
YP_932691.1	possibly involved in transport of pyrroloquinoline quinone transport
YP_932692.1	Required in the synthesis of PPQ, but its exact function is unknown
YP_932693.1	Coenzyme PQQ synthesis protein D .This family contains several bacterial coenzyme PQQ synthesis protein D (PqqD) sequences. This protein is required for coenzyme pyrrolo-quinoline-quinone (PQQ) biosynthesis. 65% similarity with Klebsiella pneumoniae and 80%; Family membership
YP_932694.1	Coenzyme PQQ synthesis protein E (Pyrroloquinoline quinone biosynthesis protein E).PART OF THE PQQ OPERON. Q88QV8: 58% identity, 74% similarity with Klebsiella pneumoniae InterProIPR000385, InterProIPR007197,PfamPF04055, SMARTSM00729, InterProIPR006638 cofactor:iron-sulfur cluster (potential). pathway:pyrroloquinoline quinone (pqq) biosynthesis. similarity: belongs to the radical sam superfamily, pqqE family TIGR PP0376; HAMAP MF_00660; Pfam PF04055; Radical_SAM; PROSITE: PS01305; MOAA_NIFB_PQQE; High confidence in function and specificity
YP_932695.1	Hypothetical protein. Has very bad homology with hits in the database. No Signficant motifs, domains or Signal peptide known to be present.
YP_932696.1	Conserved hypothetical protein. Homology to XAC0112 of X.axonopodis of 44% (trembl:Q8PR54). No domains predicted. No TMHs. No signal peptide.
YP_932697.1	Probable 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase). Homology to hppD of Pseudomonas sp. of 56% (pir|S21209) Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2. Pfam: Glaxolase/Bleomycin resistance protein no signal peptide no TMHs; Family membership
YP_932698.1	Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. tuberculosis.; Specificity unclear
YP_932699.1	DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine
YP_932700.1	Conserved hypothetical protein. Homology to ypo3484 of y. pestis of 60% (trembl|Q8ZBD2). Pfam: Luciferase-like monooxygenase. no signla peptide no TMHs
YP_932701.1	similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis
YP_932702.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_932703.1	Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]. catalyzes the trans-addition of the three molecules of ipp onto dmapp to form geranylgeranyl pyrophosphate. InterPro: Polyprenyl synthetase; High confidence in function and specificity
YP_932704.1	Probable Probable exodeoxyribonuclease VII small subunit . InterPro: Exonuclease VII small subunit.; Function unclear
YP_932705.1	AlcE: iron-sulfur-containing dioxygenases, probably involved in alcaligin biosynthesis pathway in Bordetella species. Putative iron-sulfure protein involved in aromatic compounds degradations. Choline monooxygenase chloroplast precursor (EC 1.14.15.7). Catalyzes the first step of the osmoprotectant glycine betaine synthesis. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit hypA: hydrogenase expression/formation pr; Function unclear
YP_932706.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_932707.1	Putative peptidyl-prolyl cis-trans isomerase. Homology to slpA of E. coli of 39% (sprot|FKBX_ECOLI) Accelerate protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase)(IPR001179) Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase no signal peptide no TMHs; Family membership
YP_932708.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_932709.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_932710.1	Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthetase)]. ribF: riboflavin biosynthesis protein R; High confidence in function and specificity
YP_932711.1	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No signal peptide. No TMHs
YP_932712.1	Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II). Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid. Zn dependent Hydrolase belonging to glyoxalase II family of proteins. Presence of KOW motif,and PA domain.Presence of signal peptide. probably functioning as Carbamoylphosphate synthase L chain. 50% identity and 60% similarity to Bordetella pertussis hydrolase. InterPro: Metallo-beta-lactamase superfamily gidA: glucose-inhibited division protein; Family membership
YP_932713.1	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No TMHs. No signal peptide.
YP_932714.1	TREMBLnew:CAE26305: 46% identity, 65% similarity. sprot:YJIA_ECOLI, 33% identity, 55% similarity Hypothetical protein. Pfam:cobW: Cobalmine synthesis protein; ABC_tran TIGRFAM: MMR_HSR1- GTPASE of unknown function InterPro: Cobalamin synthesis protein/P47K mobB: molybdopterin-guanine dinucleotid; Conserved hypothetical protein
YP_932715.1	Conserved hypothetical protein. Homology bll7767 of B. japonicum of 30% (trembl|Q89CN0) Pfam: WD domain, G-beta repeat no signal peptide no TMHs
YP_932716.1	Conserved hypothetical protein. Homology to Rsph03000178 of Rhodobacter sphaeroides of 37%. No domains predicted. No signal peptide. No TMHs
YP_932717.1	Conserved hypothetical secreted protein. Homology to qbdB of Pseudomonas putida of 50% (gi|22779360|dbj|BAC15558.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_932718.1	Conserved hypothetical membrane protein. Homology to Rgel02003151 of Rubrivivax gelatinosus of 37% (gi|47572524|ref|ZP_00242567.1|(NBCI ENTREZ)). PF06496,Protein of unknown function (DUF1097);IPR009476;This family consists of several bacterial putative membrane proteins. signal peptide. 4 TMHs; Conserved hypothetical protein
YP_932719.1	Part of the ABC transporter complex mntABC involved in manganese uptake. 28% Similar to the putative periplasmic-binding protein MntC precursor in N gonorrhoaeae, also involved in the resistance to oxidative stress. TREMBL:Q9F4F6 InterPro:IPR006128; Lipoprotein_4.IPR006127; SBP_bac_9. Pfam:PF01297; SBP_bac_9; 1. Signal peptide present.TMHelix:1 This operon probably is also involved in other cations uptake like Fe,Cu and Zn.This protein also could act as an adhesin which is involved on adherence to extracellular matrix.; High confidence in function and specificity
YP_932720.1	Manganese transport system ATP-binding protein mntA. This protein is probably a component of a manganese permease a binding protein-dependent ATP-driven transport system (mntABC). Probably responsible for energy coupling to the transport system. 40% AAA_ATPase.IPR003439,AAA ATPase superfamily; ABC_transporter. Pfam: PF00005; ABC_tran; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity
YP_932721.1	Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. 28% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. TmHelix:8 This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity
YP_932722.1	Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. Similar to the permease, MntB in Synechocystis 6803. 30% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity
YP_932723.1	Conserved hypothetical aromatic/alkene monooxygenase, subunit alpha Homology to blr3677 of B. japonicum (trembl|Q89P06(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). InterPro:IPR003430 Pfam: Methane/Phenol/Toluene hydroxylase (PF02332) no signal peptide no TMHs; Specificity unclear
YP_932724.1	Conserved hypothetical aromatic/alkene monooxygenase, subunit gamma. Homology to blr3678 of B. japonicum of 60% (trembl|Q89P05(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). Interpro: Phenol hydroxylase reductase family (IPR001221); Oxidoredutase FAD and NAD(P)-binding domain (IPR000134); NADH:cytochrome b5 reductase (CBR) (IPR000134) Pfam: 2Fe-2S iron-sulfur cluster binding domain; oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain no signal peptide no TMHs; Specificity unclear
YP_932725.1	Conserved hypothetical aromatic/alkene monooxygenase, subunit beta Homology to blr3679 of B. japonicum of 53% (trembl|Q89P04(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). Interpro: Methane/Penol/Toluene hydroxylase (IPR003430) Pfam: Methane/Penol/Toluene hydroxylase (PF02332) no signal peptide no TMHs; Specificity unclear
YP_932726.1	Phenol hydroxylase P2 protein (Phenol 2-monooxygenase P2 component)68% similarity to SWISSPROT:P19731,Pseudomonas sp DmpM or Phenol hydroxylase component P2, this protein lacks redox co-factors and is required for optimal turnover of Phenol hydroxylase . Phenol hydroxylase catabolises phenol and some of its methylated derivatives in the first step of phenol biodegradation, and is required for growth on phenol. The multicomponent enzyme is made up of P0, P1, P2, P3, P4 and P5 polypeptides. Pfam:PF02406, InterPro:IPR003454 91% similarity with hypothetical protein Rgel01002820 [Rubrivivax gelatinosus PM1] NO Signal Peptide No TMH's. MmoB/DmpM family; High confidence in function and specificity
YP_932727.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth
YP_932728.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH
YP_932729.1	Some bacterial regulatory proteins activate the expression of genes from promoters recognized by core RNA polymerase associated with the alternative sigma-54 factor. These have a conserved domain of about 230 residues involved in the ATP-dependent interaction with sigma-54, TREMBL:Q8RM05 (41% identity); TREMBL:Q880V5 (32% identity). Pfam (PF02954): Bacterial regulatory protein,Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; Family membership
YP_932730.1	Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. Similar to trembl|Q8YEJ0 (61%), to trembl|Q8DB12 (58%) and to trembl|Q8UCM7 (52%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase; Specificity unclear
YP_932731.1	Conserved hypothetical secreted protein. Homology to blr7490 of B. japonicum of 31% (trembl|Q89DE9(SRS)). No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein
YP_932732.1	Putative glucose dehydrogenase alpha subunit. Homology to gdhAlpha of B. cepacia of 29% (trembl|Q8GQE7) InterPro: NAD binding site (IPR000205) Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear
YP_932733.1	Hypothetical secreted protein. No good homology with hits in the database. Signal peptide present. No TMHs. No domains predicted
YP_932734.1	Conserved hypothetical membrane protein, 40% identity (49% Similarity) to TrEMBL;Q6D7F7. Signa P reporting Signal peptide present. TMHMM2 reporting 2 TMH's present.; Conserved hypothetical protein
YP_932735.1	Cytochrome D ubiquinol oxidase subunit II (EC 1.10.3.-) (Cytochrome BD-I oxidase subunit II). Cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake. Members of this family are integral membrane proteins and contain a protoheame IX center B558. It may play an important role in microaerobic nitrogen fixation. Tigrfam: cydB: cytochrome d ubiquinol oxidase subunit II Pfam: cytochrome oxidase subunit II no signal peptide 8 TMHs; High confidence in function and specificity
YP_932736.1	Probable cytochrome bd type terminal oxidase,subunit I. Homology to cydA of A. vinelandii of 67% (sprot|CYDA_AZOVI). Cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake. Members of this family are integral membrane proteins and contain a protoheame IX center B558. It may play an important role in microaerobic nitrogen fixation. InterPro: Cytochrome bd ubiquinol oxidase subunit I (IPR002585) Pfam: Bacterial cytochrome ubiquinol oxidase no singal peptide 9 TMHs; High confidence in function and specificity
YP_932737.1	Hypothetical membrane protein. no homology to to the data bank. no domains predicted. no signal peptide. 1 TMHs
YP_932738.1	Probable ranscriptional regulator,; Specificity unclear
YP_932739.1	Ubiquinol-cytochrome C reductase iron-sulfur protein. Homology to petA of R. gelantinosus of 60% (trembl|Q93SY7). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. Pfam: Riedke [2Fe-2S] domain no TMHs signal peptide; High confidence in function and specificity
YP_932740.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q88H94 (52% identity); TREMBL:Q9RXZ1 (29% identity); SWISSPROT:Q9WYC4 (25% identity). Pfam (PF00664): ABC transporter transmembrane region. Pfam (PF00005): ABC transporter. TMHMM reporting six transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership
YP_932741.1	Subtilisin Savinase precursor, 36% identity to SwissProt; P29600. Has PF00082, Subtilase family;IPR000209, Pept_S8_S53;Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see Trypsin). Structure is an alpha/beta fold containing a 7-stranded parallel beta sheet, order 2314567. PROSITE;) PS00136; SUBTILASE_ASP; 1. PS00137; SUBTILASE_HIS; 1. PS00138; SUBTILASE_SER; 1.
YP_932742.1	Conserved hypothetical secreted protein. Homology to ebA2217 of Azoarcus sp. EbN1 of 32% (gnl|keqq|eba:ebA2217(KEGG)). C-terminus is not homolog to COG0644. signal peptide present. no TMHS.; Conserved hypothetical protein
YP_932743.1	Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpA of P.putida of 50% (gi|18655859|pdb|1JMZ|A(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric enzyme containing alpha, beta and gamma chains encoded by separate genes. The alpha chain makes contact with both the beta and gamma chains. The small gamma chain forms three intra-chain cross-links via thioester bonds between cysteine and aspartic or glutamic acid residues, thereby encaging the cysteine tryptophylquinone cofactor. The largest chain, alpha, contains two heme c groups. The alpha chain is folded into four domains, domain 1 forming a diheme cytochrome. Domains 2, 3 and 4 are antiparallel beta-barrel structures. Has PF00034, Cytochromes c (cytC). Interpro (IPR009111) Quinohemoprotein amine dehydrogenase, alpha chain, domain 3. Signal peptide present. No TMHs.; High confidence in function and specificity
YP_932744.1	Conserved hypothetical qinohemoprotein amine dehydrogenase, unknown subunit. Homology to P. putida of 71% (gi|16950513|dbj|BAB72009.1|(NBCI ENTREZ)). InterPro:IPR000385; MoaA_NifB_PqqE. IPR007197; Radical_SAM. Pfam:PF04055; Radical_SAM. No signal peptide. No TMHs; Family membership
YP_932745.1	Probable quinohemoprotein amine dehydrogenase,gamma subunit. Homology to qhnDH of P. putida of 54% (sprot|QADG_PSEPK(SRS). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric enzyme containing alpha, beta and gamma chains encoded by separate genes. The alpha chain makes contact with both the beta and gamma chains. The small gamma chain forms three intra-chain cross-links via thioester bonds between cysteine and aspartic or glutamic acid residues, thereby encaging the cysteine tryptophylquinone cofactor. The largest chain,alpha, contains two heme c groups. The alpha chain is folded into four domains, domain 1 forming a diheme cytochrome. Domains 2, 3 and 4 are antiparallel beta-barrel structures. no domains predicted. no signal peptide. no TMHs; High confidence in function and specificity
YP_932746.1	Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpB of P.putida of 50% (gi|34809688|pdb|1PBY|B(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric enzyme containing alpha, beta and gamma chains encoded by separate genes. The alpha chain makes contact with both the beta and gamma chains. The small gamma chain forms three intra-chain cross-links via thioester bonds between cysteine and aspartic or glutamic acid residues, thereby encaging the cysteine tryptophylquinone cofactor. The largest chain, alpha, contains two heme c groups. The alpha chain is folded into four domains, domain 1 forming a diheme cytochrome. Domains 2, 3 and 4 are antiparallel beta-barrel structures. Interpro (IPR0011044) Quinoprotein amine dehydrogenase, beta chain-like. Signal peptide present. No TMHs.,; High confidence in function and specificity
YP_932747.1	Conserved hypothetical N-acetylmuramoyl-L-alanine amidase. Homology to amiC of R. solanaceraum of 50% (trembl|Q8XWD5) CELL-WALL HYDROLASE PROBABLY INVOLVED IN CELL-WALL HYDROLYSIS SEPTATION OR RECYCLING (BY SIMILARITY). Pfam: N-acetylmuramoyl-L-alanine amidase no signal peptide no TMHs; Family membership
YP_932748.1	Conserved hypothetical protein having uncharacterised P-loop hydrolase, 47% Identity to TrEMBL;Q82WL4,Q63WN1. Has PF02367, Uncharacterised P-loop hydrolase UPF0079;IPR003442; This signature is found in a family of bacterial proteins, which contain a P-loop.
YP_932749.1	Conserved hypothetical electron transport protein. Homology to pa4950 of P. aeruginosa of 63% (trembl|Q9HUL4). Pfam: 4Fe-4S- binding domain Tigrfam: TIG00276: iron-sulfur cluster binding protein, putative no TMHs no signal peptide TIGR00276: iron-sulfur cluster binding pr; Conserved hypothetical protein
YP_932750.1	Conserved hypothetical mandelate racemase. Homology to bll6730 of B. japonicum of 76% (trembl|Q89FH0) Mandelate racemase and muconate lactonizing enzyme are two bacterial enzymes involved in aromatic acid catabolism. They catalyze mechanistically distinct reactions yet they are related at the level of their primary, quaternary (homooctamer) and tertiary structures. InterPro: Mandelate racemase/muconate lactonizing enzyme family (IPR001354) Pfam: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain; Specificity unclear
YP_932751.1	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 29% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear
YP_932752.1	NifY-like protein. Homology to Daro03003760 of Dechloromonas aromatica of 65% (gi|46140358|ref|ZP_00203574.1|(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs.; Family membership
YP_932753.1	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No signal peptide No TMHs
YP_932754.1	Conserved Hypotheitcal protein. Very strong consideration to be a homolog for SlyX protein. TrEMBL: Q7WMX4, 32% identity. Has PF04102|SlyX;(IPR007236):The SlyX protein has no known function. It is short less than 80 amino acids and is found close to the slyD gene. The SlyX protein has a conserved PPH(Y/W) motif at its C-terminus. The protein may be a coiled-coil structure. No Signal peptide present. No TMH present.; Family membership
YP_932755.1	Conserved hypothetical peptidase. Homology to cv0266 of C. violaceum of 58% (cvi:CV0266). InterPro: Peptidase family U32 Pfam: Peptidase family U32 no signal peptide no TMHs; Family membership
YP_932756.1	Conserved hypothetical membrane protein. Homology to XCC3430 of Xanthomonas campestris of 38% (trembl:Q8P5B1). Has PF04892, VanZ like family;IPR006976 ; This family contains several examples of the VanZ protein,but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin, showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal peptide. 2 TMHs.; Conserved hypothetical protein
YP_932757.1	Similar to the GdhB protein, a putative glucose dehydrogenase-B, periplasmic protein [EC:1.1.5.2], from Synechocystis. SPTR: P73001. Signal peptide:present
YP_932758.1	Conserved hypothetical signaling protein. Homology to Bcep02001865 of Burkholderia fungorum of 44% (gi|48787085|ref|ZP_00283167.1|(NBCI ENTREZ)). InterPro: IPR003660 HAMP. IPR000160 GGDEF. Pfam: PF00672 HAMP. PF00990 GGDEF domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices (in signal peptide).; Conserved hypothetical protein
YP_932759.1	Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Similar to trembl|Q986V8 (37%). Pfam (PF01547): Bacterial extracellular solute-binding protein; Family membership
YP_932760.1	Putative serin/threonine protein kinase, only very low similarity to SWISSPROT: sprot|PKSC_STRCO (13% Streptomyces coelicolor, serine/threonine protein kinase PksC (EC 2.7.11.1)) / TREMBL: trembl|Q9S478 (13% Myxococcus xanthus, Pkn4). Pfam: PF00069 Pkinase. SMART:SM00221 STYKc (Protein kinase; unclassified specificity). SM00065 GAF (Domain present in phytochromes and cGMP-specific phosphodiesterases).; Family membership
YP_932761.1	Conserved hypothetical protein. Homology to CV1784 of C.violaceum of 40% (tremble:Q7NX45). No domains predicted. No TMHs. No signal peptide.
YP_932762.1	hypothetical membrane protein no homology to entire proteins seven transmembrane domains predicted, no signal peptide predicted; Family membership
YP_932763.1	Probable aminoacyl-histidine dipeptidase (EC 3.4.13.3) (Xaa-His dipeptidase) (X-His dipeptidase) (Beta-alanyl-histidine dipeptidase) (Carnosinase) (Peptidase D). Homology to pepD of E. coli of 44%. THIS DIPEPTIDASE HAS SPECIFICITY FOR THE UNUSUAL DIPEPTIDE BETA-ALANYL-L-HISTIDINE. InterPro: Peptidase family M20/M25/M40 (IPR002933) Pfam: Peptidase family M20/M25/M40 no signal peptide no TMHs; High confidence in function and specificity
YP_932764.1	Conserved hypothetical protein. Homology to RPA1575 of R.palustris of 41% (tremble:Q6N9H4). Has PF04536:(IPR007621)Domain of unknown function (DUF477);This is a family of uncharacterised proteins. They are found in both eukarya and eubacteria. No TMHs. No signal peptide.
YP_932765.1	Conserved hypothetical membrane protein. Homology to Bll7266 of B. japonicum of 45% (trembel:Q89E21) InterPro:IPR007621; DUF477. Pfam:PF04536; DUF477 Signal peptide present (Signal P predicted). Presence of 2 transmembrane helices.; Conserved hypothetical protein
YP_932766.1	Putative lipoprotein [lemA],57 % identity (75% similarity) to TrEMBL;Q72TG3,TrEMBL;Q6N9H6(60% identity). No signl peptide or TMH present. Has PF04011:LemA family(IPR007156,lemA);The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular [1]. The exact molecular function of this protein is uncertain.; Conserved hypothetical protein
YP_932767.1	Conserved yhpothetical protein. Homology to BP1565 of B.pertussis of 66% (tremble:Q7VY02) Has PF07311:Protein of unknown function (DUF1458)(IPR009923 );This family consists of several hypothetical bacterial proteins as well as one archaeal sequence Q9HPW4. Members of this family are typically of around 70 residues in length. The function of this family is unknown. No signal peptide or TMH present.
YP_932768.1	Putative transmembrane sensor protein, no similarity to other bacterial proteins. Best hits to mus musculus and homo sapiens. Domains (LCCL_dom and TIR) are found in proteins (animal and plants) involved in protection against bacterial infection. InterPro: IPR004043 LCCL_dom. IPR000157 TIR. TMHMM reporting 1 transmembrane helices.
YP_932769.1	Hypothetical protein, 26% identity(49% similarity) to TrEMBL;Q8XT66. TrEMBL;Q7P1L8(34% identity). No domains,repeats, motifs or features present.
YP_932770.1	Putative chaperone protein dnaJ. homology to dnaJ of E. coli of 32% (sprot|DNAJ_ECOLI) Acts as a co-chaperone. Stimulates jointly with grpE the ATPase activity of dnaK (By similarity). Pfam: DnaJ domain, DnaJ central domain (4 repeats), DnaJ Cterminal region no singal peptide no TMHs; Family membership
YP_932771.1	Entry name TREMBL:Q7W380 Prim. accession # Q7W380 Identities = 111/150 (74%) InterPro IPR006683; Thioestr_supf. Pfam PF03061; 4HBT; 1. Prediction: Non-secretory protein Signal peptide probability: 0.179 Number of predicted TMHs: 0; Family membership
YP_932772.1	Conserved hypothetical protein. Homology to PBPRB0126 of Photobacterium profundum of 54% (trembl:Q6LL06). No domains predicted. No TMHs. No signal peptide.
YP_932773.1	non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis
YP_932774.1	Probable Branched-chain amino acid aminotransferase (EC 2.6.1.42) (Transaminase B) (BCAT). thrC: threonine synthase.; Function unclear
YP_932775.1	Conserved hypothetical secreted protein. Homology to pa3214 of P. aeruginosa of 52% (trembl|Q9HZ26). Pfam: DUF330 signal peptide no TMHs; Conserved hypothetical protein
YP_932776.1	Conserved hypothetical secreted protein. Similar to TREMBL:Q9HZ27 (53% identity); TREMBL:Q88RI9 (46% identity); TREMBL:Q8PGP4 (33% identity). Pfam (PF02470): mce related protein. SignalP reporting signal peptide. No TMHs; Conserved hypothetical protein
YP_932777.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8PGP5 (60% identity); TREMBL:Q9PDS7 (57% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear
YP_932778.1	TREMBL:Q88RI7 (56% identity); TREMBL:Q8PGP6 (42% identity). Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting six transmembrane helices.; Specificity unclear
YP_932779.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_932780.1	Putative methyltransferase Rv0089/MT0098/Mb0092 (EC 2.1.1.-). Methyl transfer from the ubiquitous S-adenosyl-L-methionine (AdoMet) to either nitrogen, oxygen or carbon atoms is frequently employed in diverse organisms TREMBL:AAS95087-36%identity,50% similarity InterPro: SAM (and some other nucleotide) binding motif rrmJ: ribosomal RNA large subunit methylation TIGRFAM:Transcription regulator, AsR family, Ubi/COQ family.; Family membership
YP_932781.1	conserved hypothetical glutathione peroxidase. Homolgy to pp1874 pf P. putida of 66% (trembl|Q88LQ5) Glutathione peroxidase (GSHPx), an enzyme whose principal function is to protect against damage from endogenously-formed hydroxyperoxides, catalyses the reduction of hydroxyperoxides by glutathione Pfam: Glutatione peroxidase no signal peptide no TMHs; Family membership
YP_932782.1	EAL/GGDEF/PAS/PAC-domain containing signalling protein,; Conserved hypothetical protein
YP_932783.1	Probable cytochrome c peroxidase (EC 1.11.1.5), an electron-transfer proteins having one or several haem c groups, bound to the protein by one or, more generally,two thioether bonds involving sulphydryl groups of cysteine residues. CytC possess a wide range of properties and function in a large number of different redox processes. Similar to yhjA from E.coli.; High confidence in function and specificity
YP_932784.1	Ferredoxin-NADP+ reductase (EC 1.18.1.2) Homology to fpr of A. vinelandii of 79% (sprot|FENR_AZOVI). CATALYTIC ACTIVITY: Reduced ferredoxin + NADP(+) = oxidized ferredoxin + NADPH. Pfam: Oxidoreductase FAD-binding doamin; Oxidoreductase NAD-binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_932785.1	Probable transcriptional regulator, LysR family proteins.57% Identity to TrEMBL;Q9HYK6, Q87XZ5, Q88MD6. Has PF03466, LysR substrate binding domain;IPR005119,LysR_subst; The structure of this domain is known and is IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family,groups together a range of proteins, including ampR, catM,catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR,mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR,syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini.; High confidence in function and specificity
YP_932786.1	Beta-(1-3)-glucosyl transferase, involved in the synthesis of the cyclic beta-(1,3),(1,6)-D-glucan. 36% Glyco_trans_2. Pfam:PF00535; Glycos_transf_2. Signal peptide: present. TMhelix:9.; Function unclear
YP_932787.1	Conserved hypothetical membrane protein. Homology to PP1739 of P. putida of 30% (trembl|Q8EA80) No domains predicted. signal peptide 2 TMHs; Conserved hypothetical protein
YP_932788.1	Glucan 1-3-beta-glucosidase precursor.(Exo-13-beta-glucanase).Glucanases possibly play a role in cell expansion during growth in cell-cell fusion during mating and in spore release during sporulation. This enzyme may be involved in beta- glucan degradation and also function biosynthetically as a transglycosylase. 47%; Function unclear
YP_932789.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine
YP_932790.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_932791.2	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_932792.1	Probable nitrate transporters are involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. NarK is polytopic membrane protein with 12 transmembrane domains which is involved in nitrate uptake and nitrite excretion and is thought to function as a nitrate/nitrite antiporter. At low concentrations of nitrate, NarK mediates the electrogenic excretion of nitrite rather than nitrate/nitrite exchange., 90% similarity to a probable nitrate transporter protein in Azoarcus sp. EbN1., InterPRo:04737: nitrate transporterSignal peptide no present, TMHx:12 ,; High confidence in function and specificity
YP_932793.1	Putative serine/threonine protein kinase,; Family membership
YP_932794.1	Conserved hypothetical protein. Homology to ebA98 of Azoarcus sp. EbN1 of 67% (gnl|keqq|eba:ebA983(KEGG)). No domains predicted. No signal peptide. No TMHs
YP_932795.1	Putative phosphohistidine phosphatase, SixA. TIGRFAM: TIGR00249; sixA. Phosphohistidine phosphatase sixA (EC 3.1.3.-) (RX6). EXHIBITS PHOSPHOHISTIDINE PHOSPHATASE ACTIVITY TOWARDS THE HPT DOMAIN OF THE ARCB SENSOR INVOLVED IN THE MULTISTEP HIS- ASP PHOSPHORELAY.; Specificity unclear
YP_932796.1	Conserved hypothetical protein,40% identity to TrEMBL;Q88AR4 Has PF01928|CYTH domain(IPR008172);These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3',5'-cyclic AMP and pyrophosphate. Has PF05235:CHAD domain(IPR007899);The CHAD domain is an alpha-helical domain functionally associated with the CYTH domains. It has conserved histidines that may chelate metals.
YP_932797.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
YP_932798.1	Conserved hypothetical protein. Homology to cv2096 of C. violaceum of 32% (trembl|Q7NW94(SRS) no domains predicted no signal peptide 1 TMHs
YP_932799.1	conserved hypothetical carbon-nitrogen hydrolase. Homolog to bb1933 of B. bronchiseptica (trembl|Q7WL17). InterPro: Carbon-nitrogen hydrolase (IPR003010) Pfam: Carbon-nitorgen hydrolase no signal peptide no TMHs; Conserved hypothetical protein
YP_932800.1	Probable TldD protein. Homology to tldD of E. coli of 59% (sprot|TLDD_ECOLI). Suppresses the inhibitory activity of the carbon storage regulator (csrA). Pfam: putative modulator of DNA gyrase no signal peptide no TMHs; Function unclear
YP_932801.1	Conserved hypothetical protein. Homology to CV3985 of C.violaceum of 42% (tremble:Q7NR00). Has PF07025:(IPR010745)Protein of unknown function (DUF1316);This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. No signal peptide or TMH present.
YP_932802.1	Conserved hypothetical membrane protein. Homology to cv3984 of C. violaceum of 47% (trembl|Q7NR01(SRS)) no domains predicted no signal peptide 1 TMH; Conserved hypothetical protein
YP_932803.1	Hypothetical protein,50% identity (67% similarity)to TrEMBL;Q7NR02. TrEMBL;Q88IA6(39%),Q8XRU1(37%). Has PF05936(IPR010263):Bacterial protein of unknown function (DUF876);This family consists of a series of hypothetical bacterial sequences of unknown function. No Signal Peptide or TMH reported present.; Function unclear
YP_932804.1	Hypothetical protein,34% identity (52% similarity) to TrEMBL;Q7NR03. No domains, repeats, motifs or features were predicted with confidence.; Function unclear
YP_932805.1	Hypothetical membrane protein. No homology of the entire protein with the data bank. Pfam: D-alanyl-D-alanine carboxypeptidase (101-209 aa) no signal peptide 1 TMHs
YP_932806.1	Conserved hypothetical membrane protein. Homology to CV3712 of Chromobacterium violaceum of 35% (trembl|Q7NR05) Signal P reporting Signal Peptide Present. TMHMM2 reporting 2 TMH's present. Has PF06761:(IPR009612)ImcF-related;This family represents a conserved region within several bacterial proteins that resemble ImcF, which has been proposed [1] to be involved in Vibrio cholerae cell surface reorganisation, resulting in increased adherence to epithelial cells and increased conjugation frequency. Note that many family members are hypothetical proteins. Has PF06744,(IPR010623)Protein of unknown function (DUF1215);This family represents a conserved region situated towards the C-terminal end of several hypothetical bacterial proteins of unknown function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency.; Conserved hypothetical protein
YP_932807.1	Hypothetical protein,50% identity (66% Similarity) to TrEMBL;Q8XRT8. TrEMBL;Q7NR06(60% identity,74% similarity). Has PF05591;Protein of unknown function (DUF770)(IPR008312)This family consists of several proteins of unknown function from various bacterial species. No Signal peptide or TMH present.; Function unclear
YP_932808.1	Hypothetical protein,63% identity (81% similarity) to TrEMBL;Q8XRT7. TrEMBL;Q7NR07(73% identity,86% similarity). Has (IPR010269 )PF05943:Protein of unknown function (DUF877);This family consists of a number of uncharacterised bacterial proteins. The function of this family is unknown. No Signal peptide or TMH present.; Function unclear
YP_932809.1	Conserved hypothetical protein. Homology to CV3977 of C.violaceum of 77% (tremble:Q7NR08). Has PF05638:(IPR008514)Protein of unknown function (DUF796);This family consists of several bacterial proteins of unknown function. No signal peptide or TMH present.
YP_932810.1	Hypothetical secreted protein. Homology to CV3976 of Chromobacterium violaceum of 26% (trembl|Q7NR09(SRS)). No TMHs Signal Peptide Present. Has PF00691:OmpA family;(IPR006665 OmpA/MotB):The Pfam entry also includes MotB and related proteins which are not included in the Prosite family.
YP_932811.1	Probable vgr-related protein,41% identity (55% similarity) to TrEMBL;Q7NY43. TrEMBL;Q8XSF8 Has (IPR006533 Rhs_Vgr)PF04524:Protein of unknown function, DUF586;This family contains a conserved region in several bacterial proteins of unknown function. Coils2 program predicts presence of a coiled coil.
YP_932812.1	Conserved hypothetical protein. Homology to CV3969 of C.violaceum of 56% (tremble: Q7NR16). Has (IPR010272)PF05947:Bacterial protein of unknown function (DUF879);This family consists of several hypothetical bacterial proteins of unknown function. No signal peptide or TMH present.
YP_932813.1	Conserved hypothetical protein. Homology to CV3967 of C.violaceum of 45% (tremble:Q7NR18) Has (IPR010732)PF06996:Protein of unknown function (DUF1305);This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence. No signal peptide or TMH reported present.
YP_932814.1	Conserved hypothetical protein. Homology to CV3963 of C.violaceum of 37% (tremble:Q7NR22). Has (IPR01065)PF06812:ImpA-related N-terminal;This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. Note that many family members are hypothetical proteins. No signal peptide present. No TMH present.
YP_932815.1	conserved hypothetical protein Has 2 PF05488 PAAR motif(IPR008727);This motif is found usually in pairs in a family of bacterial membrane proteins. It is also found as a triplet of tandem repeats comprising the entire length in a another family of hypothetical proteins.; Function unclear
YP_932816.1	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs
YP_932817.1	PhnA protein: Phosphonoacetate hydrolase is a novel carbon-phosphorus bond cleavage enzyme.The phnA gene is part of a large operon in Escherichia coli associated with alkylphosphonate uptake and carbon-phosphorus bond cleavage. PhnA is found in both gram positive 69% PhnA.PhnA protein Pfam:PF03831; PhnA; 1. TIGRFAMs:TIGR00686; phnA; 1.; High confidence in function and specificity
YP_932818.1	Conserved hypothetical protein. Homology to ebA3072 Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA3072(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_932819.1	Conserved hypothetical membrane protein. Homology to blr8071 of B. japonicum of 56% (trembl|Q89BS7). No domains predicted signal peptide probable 6 TMHs; Conserved hypothetical protein
YP_932820.1	47% AAA_ATPase.IPR003439; ABC_transporter.IPR008995. Pfam:PF00005; ABC_tran; 1. SMART:SM00382; AAA; 1. non-secretory protein; Function unclear
YP_932821.1	Conserved hypothetical protein. Homology to CCO1214 of Campylobacter coli of 38% (gi|57168023|ref|ZP_00367162.1|(NBCI ENTREZ)). Has PF07021, Methionine biosynthesis protein MetW;IPR010743; This family consists of several bacterial and one archaeal methionine biosynthesis MetW proteins. Biosynthesis of methionine from homoserine in Pseudomonas putida takes place in three steps. The first step is the acylation of homoserine to yield an acyl-L-homoserine. This reaction is catalysed by the products of the metXW genes and is equivalent to the first step in enterobacteria, gram-positive bacteria and fungi, except that in these microorganisms the reaction is catalysed by a single polypeptide (the product of the metA gene in Escherichia coli and the met5 gene product in Neurospora crassa). In Pseudomonas putida, as in gram-positive bacteria and certain fungi, the second and third steps are a direct sulfhydrylation that converts the O-acyl-L-homoserine into homocysteine and further methylation to yield methionine. The latter reaction can be mediated by either of the two methionine synthetases present in the cells. No signal peptide. No TMHs.
YP_932822.1	Conserved hypothetical membrane protein. Homology to RS04440 of Ralstonia solanacearum of 40% (trembl|Q8Y277) TMHMM2 reporting 2 TMH's present. Signal peptide Present. Has PF04280;Tim44-like domain(IPR007379):Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostatic interactions and by penetrating the polar head group region. This family includes the C-terminal region of Tim44 that has been shown to form a stable proteolytic fragment in yeast. This region is also found in a set of smaller bacterial proteins. The molecular function of the bacterial members of this family is unknown but transport seems likely.; Conserved hypothetical protein
YP_932823.1	Hypothetical protein Rv1403c/MT1447/Mb1438c precursor. TREMBL:Q92U99_Putative methyl transferase, S-adenosyl-L-methionine (SAM)-29% identity, 42% similarity. InterPro: ubiE/COQ5 methyltransferase pimt: protein-L-isoaspartate O-methyltr Pfam: ubiE/COQ5 methyl transferase family, Dihydrodipicolinate synthetase family, TerD (Bacterial stress protein domains). HTH_1 predicted regulatory helix turn helix. TIGRFAM: moaC, met p-daseII; Specificity unclear
YP_932824.1	Putative AraC-family transcriptional regulator,; Family membership
YP_932825.1	Conserved hypothetical protein. Homology to Psyc03001842 of Psychrobacter sp. 273-4 of 57% (gi|52853589|ref|ZP_00145853.2|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_932827.1	Probable protein kinase InterPro: Protein kinase,Protein kinase-like
YP_932828.1	C-terminal part of GTP-binding protein hflX. TREMBL:Q7NU63: 66% identity; 83% similarity ( the protein of query matches only with C-terminal part (124 aminoacids) of putative GTP binding proteins in the database) InterPro:IPR006073; GTP1_OBG. PRINTS:PR00326; GTP1OBG Pfam:Sigma54_activat: Sigma-54 interaction domain Absence of transmembrane helices (TMHMM predicted); Function unclear
YP_932829.1	Region start changed from 1443402 to 1443378 (-24 bases), , Changed start codon from att to next atg
YP_932830.1	Hypothetical Protein. No domains, repeats, motifs or features could be predicted above threshold scores.
YP_932831.1	GTP-binding protein hflX. trembl:Q7NU63:77% identity, 83% similarity The proteins contain GTP-binding motifs and are GTP1_OBG. PRINTS:PR00326; GTP1OBG Pfam:MMR_HSR1:GTPase of unknown function thdF: tRNA modification GTPase TrmE No signal peptide present (SignalP predicted). No transmembrane helices present (TMHMM predicted); Family membership
YP_932832.1	Conserved hypothetical protein. Fusion Protein of bacterial extracellular solute-binding protein and transglycosylase Homology to pp1036 of P. putida of 37% (trembl|Q88P17) InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein/glutamate receptor (IPR001311); SLT domain (IPR000189) Pfam: Bacterial extracellular solute-binding protein; Transglycosylase SLT domain signal peptide no TMHs recN: DNA repair protein RecN
YP_932833.1	Putative amino-acid ABC transporter permease. Homology to aapM of R. leguminosarum of 38% (sprot|AAPM_RHILV) PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YDHWXYZ FOR AN AMINO ACID; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. Pfam: binding-protein-dependent transport system signal peptide probable 8 TMHs; Family membership
YP_932834.1	Putative amino acid permease. Homology to aapQ of R. leguminosarum of 35% (sprot|AAPQ_RHILVast). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR L-AMINO ACIDS. AFFECTS THE UPTAKE AS WELL AS EFFLUX OF THESE AMINO ACIDS. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein -dependent transport system 1 HTH no signal peptide probable 4 TMHs; Family membership
YP_932835.1	Putative amino acid ABC transporter periplasmic binding protein. Homology to aapJ of R. leguminosarum of 52% (sprot|AAPJ_RHILV). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR L-AMINO ACIDS AFFECTS THE UPTAKE AS WELL AS EFFLUX OF THESE AMINO ACIDS. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein/glutamate receptor (IPR001311) Pfam: Bacterial extracellular solute-binding proteins signal peptide no TMHs TIGR00045: conserved hypothetical prote; High confidence in function and specificity
YP_932836.1	HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 55% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity
YP_932837.1	Sulfate/thiosulfate import ATP-binding protein cysA (EC 3.6.3.25) (Sulfate-transporting ATPase). Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system (By similarity). InterPro: AAA ATPase superfamily ruvB: Holliday junction DNA helicase Ru; High confidence in function and specificity
YP_932838.1	Sulfate transport system permease cysW. Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane. InterPro: Binding-protein-dependent transport systems inner membrane component uppS: undecaprenyl diphosphate synthase; High confidence in function and specificity
YP_932839.1	Probable sulfate transport system permease cysT. Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). InterPro: Binding-protein-dependent transport systems inner membrane component gntP: gluconate transporter; High confidence in function and specificity
YP_932840.1	CysP: sulfate/thiosulfate periplasmic binding protein. Sulfate-binding protein precursor (Sulfate starvation-induced protein 2) (SSI2). This protein specifically binds sulfate and is involved in its transmembrane transport. mazG: MazG family protein; High confidence in function and specificity
YP_932841.1	Conserved hypothetical peptidoglycan binding protein. Homology to bb3579 of b. bronchiseptica of 69% (trembl|Q7WGL0) InterPro: Putative peptidoglycan binding domain 1 (IPR002477) Pfam: Putative peptidoglycan binding domain This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. signal peptide no TMHs; Family membership
YP_932842.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8FWK3 (58% identity); TREMBL:Q9AHY1 (58% identity). Pfam (PF00106): Short chain dehydrogenase.; Family membership
YP_932843.1	36% ATPase-IB1_Cu.IPR006416; ATPase-IB_hvy.IPR001757; ATPase_E1-E2.IPR005834; Dehal_like_hydro.IPR008250; E1-E2_ATPase_reg. IPR006121; HeavyMe_transpt.IPR000695; H_ATPase.IPR006191; Metal_bind. Pfam:PF00122; E1-E2_ATPase; 1.PF00403; HMA; 1.PF00702; Hydrolase; 1. TMHs:8; Specificity unclear
YP_932844.1	Conserved hypothetical cytochrome oxidase maturation protein. Homology to cco of P.Putida of 42% (gnl|keqq|ppu:PP4262(KEGG)). Pfam: Cytochrome oxidase maturation protein cbb3-type. Genes encoding a cytochrome cbb3 oxidase were initially designated fixNOQP (ccoNOQP),the ccoNOQP operon is always found close to a second gene cluster, known as fixGHIS (ccoGHIS) whose expression is necessary for the assembly of a functional cbb3 oxidase. On the basis of their derived amino acid sequences each of the four proteins encoded by the ccoGHIS operon are thought to be membrane-bound. It has been suggested that they may function in concert as a multi-subunit complex,possibly playing a role in the uptake and metabolism of copper required for the assembly of the binuclear centre of cytochrome cbb3 oxidase. Interpro: IPR004714 Cytochrome oxidase maturation protein cbb3-type. No signal peptide. 1 TMHs; Conserved hypothetical protein
YP_932845.1	CcoN; FixN
YP_932846.1	CcoO; FixO
YP_932847.1	Cbb3-type cytochrome oxidase, subunit ccoQ , 44% Identity to TrEMBL;Q8D9I3, Q7MKV5,Q9KS21. Has PF05545,Cbb3-type cytochrome oxidase component FixQ; IPR008621;This family consists of several Cbb3-type cytochrome oxidase components (FixQ/CcoQ). FixQ is found in nitrogen fixing bacteria. Since nitrogen fixation is an energy-consuming process, effective symbioses depend on operation of a respiratory chain with a high affinity for O2, closely coupled to ATP production. This requirement is fulfilled by a special three-subunit terminal oxidase (cytochrome terminal oxidase cbb3), which was first identified in Bradyrhizobium japonicum as the product of the fixNOQP operon.
YP_932848.1	Probable cytochrome C oxidase subunit III. Homology to ccoP of P. stutzeri of 46% (trembl|Q8KS19) CYTOCHROME C OXIDASE IS THE COMPONENT OF THE RESPIRATORY CHAIN THAT CATALYZES THE REDUCTION OF OXYGEN TO WATER. SUBUNITS 1- 3 FORM THE FUNCTIONAL CORE OF THE ENZYME COMPLEX. CO I IS THE CATALYTIC SUBUNIT OF THE ENZYME. ELECTRONS ORIGINATING IN CYTOCHROME C OR A QUINOL ARE TRANSFERRED TO THE BIMETALLIC CENTER FORMED BY A HIGH-SPIN HEME AND COPPER B. Tigrfam: ccoP: cytochrome c oxidase cbb3-type Pfam: cytochrome c no signal peptide probable 2 TMHs; High confidence in function and specificity
YP_932849.1	Putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to fixG of R. meliloti of 36% (FIXG_RHIME). Ferredoxins are iron-sulphur proteins that mediate electron transfer in a range of metabolic reactions; they fall into several subgroups according to the nature of their iron-sulphur cluster(s). One group,originally found in bacteria, has been termed ''bacterial-type'', in which the active centre is a 4Fe-4S cluster. 4Fe-4S ferredoxins may in turn be subdivided into further groups, based on their sequence properties. Most contain at least one conserved domain, including four Cys residues that bind to a 4Fe-4S centre. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) probable 5 TMHs . No signal peptide predicted.; Family membership
YP_932850.1	Conserved hypothetical membrane protein. Homology to ebA5136 Azoarcus sp. EbN1 of 51% (gnl|keqq|eba:ebA5136(KEGG)). Has PF05751, FixH;IPR008620; This family consists of several Rhizobium FixH like proteins. It has been suggested that suggested that the four proteins FixG, FixH, FixI, and FixS may participate in a membrane-bound complex coupling the FixI cation pump with a redox process catalysed by FixG. No signal peptide predicted. 1 TMHs; Conserved hypothetical protein
YP_932851.1	Hypothetical membrane protein. No homology to the data bank. No domain predicted. No signal peptide 1 TMH
YP_932852.1	Probable transmemebrane Protein, 38% Idneity to TrEMBL;Q8XZW3 Signal P reporting Signal peptide present. TMHMM2 reporting 1 TMH present.
YP_932853.1	Putative universal stress protein F,; Conserved hypothetical protein
YP_932854.1	FUNCTION: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name :-PHBC_AZOCA Primary accession number:- O66392 Identity:-41% InterPro :- IPR000073; A/b_hydrolase. Pfam:- PF07167; PhaC_N; 1. Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_932855.1	Fumarate and nitrate reduction regulatory protein. Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor O(2) is no longer available it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration. Similar to SWISSPROT: sprot|FNR_ECOLI (39% Escherichia coli, fumarate and nitrate reduction regulatory protein Fnr) / sprot|ANR_PSEAE (40% Pseudomonas aeruginosa,transcriptional activator protein Anr) InterPro: IPR000595 cNMP_binding. IPR001808 HTH_Crp. Pfam: PF00027 cNMP_binding. PF00325 Crp. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_932856.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_932857.1	Conserved hypothetical membrane protein. Homology to ebA5153 of Azoarcus sp. EbN1 of 79% (gnl|keqq|eba:ebA5153(KEGG)). Has PF02683;Cytochrome C biogenesis protein transmembrane region (IPR003834 Ctytoch_TM): This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins. These proteins posses a protein disulphide isomerase like domain that is not found within the aligned region of this family. No signal peptide. 5 TMHs; Conserved hypothetical protein
YP_932858.1	Heavy metal dependent transcription regulator 2. TRANSCRIPTIONAL REGULATOR INVOLVED IN ACID TOLERANCE. BINDS COPPER (By similarity). It contains a n-terminal dna binding region and a c- terminal metal binding region (by similarity). 35% HTH_MerR.IPR009061; Putativ_DNA_bind. Pfam:PF00376; MerR; 1. TIGR00372: conserved hypothetical protei; High confidence in function and specificity
YP_932859.1	CopA: copper transporting P-type ATPase,involved in the uptake and metabolism of copper. 44% ATPase-IB1_Cu.IPR006416; ATPase-IB_hvy.IPR001757; ATPase_E1-E2.IPR001756; Cu_ATPase.IPR005834; Dehal_like_hydro.IPR008250; E1-E2_ATPase_reg.IPR006121; HeavyMe_transpt.IPR006191; Metal_bind. Pfam:PF00122; E1-E2_ATPase; 1.PF00403; HMA; 1.PF00702; Hydrolase; 1. TIGR00003: copper-ion-binding protein. TMHs:8.; High confidence in function and specificity
YP_932860.1	Conserved hypothetical copper chaperon. Homology to copZ of copZ Azoarcus sp. EbN1 of 66%. Pfam: Heavy-metal-associated domain. Proteins that transport heavy metals in micro-organisms and mammals share similarities in their sequences and structures. Tigrfam: TIGR00003: copper-ion-binding protein. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_932861.1	EAL/GGDEF/PAS/PAC-domain containing signalling protein,; Conserved hypothetical protein
YP_932862.1	Probable inorganic pyrophosphatase. Homology to ppa of E. coli of 66% (sprot|IPYR_ECOLI). CATALYTIC ACTIVITY Diphosphate + H(2)O = 2 phosphate. Pfam: Inorganic pyrophospatease no signal peptide no TMHs; High confidence in function and specificity
YP_932863.1	Conserved hypothetical protein. Homology to BB3581 of B.bronchiseptica of 53% (tremble:Q7WGK8). Has PF04339:(IPR00743)Protein of unknown function, DUF482;This family contains several proteins of uncharacterised function. NO signal peptide or TMH present.
YP_932864.1	NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_932865.1	PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ2 (100%) and to trembl|Q8XWX5 (82%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity
YP_932866.1	Hypothetical protein. no homology of the entire protein with the data bank. Pfam: Smr domain InterPro: Smr domain This family includes the Smr (Small MutS Related) proteins, and the C-terminal region of the MutS2 protein. It has been suggested that this domain interacts with the MutS1 protein in the case of Smr proteins and with the N-terminal MutS related region of MutS2. no signal peptide no TMHs
YP_932867.1	Thioredoxin-disulfide reductase(EC 1.8.1.9). Homology to trxB of E. coli of 71% (sprot|TRXB_ECOLI). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; High confidence in function and specificity
YP_932868.1	Probable cyclic amp receptor-like protein,; High confidence in function and specificity
YP_932869.1	DNA translocase ftsK 2. InterPro: FtsK/SpoIIIE family; High confidence in function and specificity
YP_932870.1	Putative outer-membrane lipoprotein carrier protein. Homology to lolA of E. coli of 25% (sprot|LOLA_ECOLI) Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity). Pfam: outer membrane lipoprotein carrier protein LolA Tigrfam: lolA: outer membrane lipoprotein carrier singal peptide no TMHs; Family membership
YP_932871.1	Hypothetical protein CBU1189. InterPro: AAA-protein (ATPases associated with various cellular activities) ruvB: Holliday junction DNA helicase R.; Specificity unclear
YP_932872.1	Conserved hypothetical protein. Homology to ebA7035 of Azoarcus sp. EbN1 of 79% (gnl|keqq|eba:ebA7035(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_932873.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_932874.1	Aerotaxis receptor protein,; Specificity unclear
YP_932875.1	Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089); Pyridine nucleotide-disulphide oxidoreductase dimersiation domain (IPR004099); NAD binding site (IPR000205); 2-oxo acid dehydrogenase acetyltransferase, classI (IPR003016) Pfam: Biotin-requiring enzyme; Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide oxidoreductase dimersation domain no TMHs no signal peptide; High confidence in function and specificity
YP_932876.1	Probable dihydrolipoamide acetyltransferase. Homology to pdhB of A. eutrophus of 62% (sprot|ODP2_ALCEU) THE PYRUVATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF PYRUVATE TO ACETYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF THREE ENZYMATIC COMPONENTS: PYRUVATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2) & LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: 2-Oxo acid dehydrogenase acyltransferase catalytic domain (IPR001078); Type I antifreeze protein (IPR000104); Biotin/Lipoyl attachment (IPR000089); E3 binding domain (IPR004167); 2-Oxo acid dehydrogenase acyltransferase component lipoyl binding site (IPR003016) Pfam: Biotin-requiring enzyme; E3 binding domain; 2-oxo dehydrogenase acyltransferase Tigrfam: BCCP: acetyl-CoA carboxylase biotin carboxyl carrier protein no TMHs no signal peptide; High confidence in function and specificity
YP_932877.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
YP_932878.1	This family includes extracellular ligand binding domains of a wide range of receptors and it also includes the bacterial amino acid binding proteins of known structure. Similar to tremblnew|AAR35111 (24%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Family membership
YP_932879.1	Putative two-component sensor kinase,; Specificity unclear
YP_932880.1	Probable transcriptional regulatory protein,; Specificity unclear
YP_932881.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_932882.1	Phosphoribosylaminoimidazole carboxylase(AIR carboxylase) (AIRC). InterPro: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; High confidence in function and specificity
YP_932883.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_932884.1	Hypothetical protein ywlC. TIGR00057: Sua5/YciO/YrdC/YwlC family; Specificity unclear
YP_932885.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_932886.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_932887.1	Transcription elongation factor GreA Transcription elongation factor greA (Transcript cleavage factor greA). Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as greA or greB allows the resumption of elongation from the new 3terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity). Belongs to the greA/greB family. 58% 1. PF03449 GreA_GreB_N; 1. TIGFRAM TIGR01462; greA; 1. PurN: phosphoribosylglycinamide formylt; High confidence in function and specificity
YP_932888.1	Conserved hypothetical membrane protein. Homology to RS03781 of Ralstonia solanacearum of 39% (trembl|Q8XZ81(SRS)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein
YP_932890.1	Ribosomal RNA large subunit methyltransferase J (EC 2.1.1.-) (rRNA (uridine-2-O-)-methyltransferase) (23S rRNA m2U2552 methyltransferase) (Cell division protein ftsJ homolog). Specifically methylates the uridine in position 2552 of 23S rRNA in the 50S particle; High confidence in function and specificity
YP_932891.1	Cell division protease ftsH. Homology to ftsH of E. coli of 64% (SWISSPROT:FTSH_ECOLI) SEEMS TO ACT AS AN ATP-DEPENDENT ZINC METALLOPEPTIDASE. INVOLVED IN THE DEGRADATION OF SIGMA-32. DEGRADES CARBOXY- TERMINAL-TAGGED CYTOPLASMIC PROTEINS. THESE PROTEINS ARE TAGGED WITH AN 11-AMINO-ACID NONPOLAR DESTABILIZING TAIL VIA A MECHANISM INVOLVING THE 10SA (SSRA) STABLE RNA (By similarity). Pfam: ATPase family associated with various celluar activities;Peptidase family M41 probable signal peptide probable 1 TMH; High confidence in function and specificity
YP_932892.1	Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase). DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide (By similarity).; High confidence in function and specificity
YP_932893.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_932894.1	61% Peri-phosph.IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR00975; 3a0107s03; 1. Signal peptide present.; High confidence in function and specificity
YP_932895.1	part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions
YP_932896.1	Region start changed from 1521840 to 1521903 (-63 bases)
YP_932897.1	Phosphate import ATP-binding protein pstB (EC 3.6.3.27) (Phosphate- transporting ATPase) (ABC phosphate transporter) (Peripheral membrane protein B). Part of the ABC transporter complex pstSACB (TC 3.A.1.7.1) involved in phosphate import. Responsible for energy coupling to the transport system. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity
YP_932898.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_932899.1	Protein-export membrane protein secG. Involved in protein export. Participates in an early event of protein translocation (By similarity). Together with SecY and SecG, SecE forms a multimeric channel through which preproteins are translocated, using both proton motive forces and ATP-driven secretion. pfam: preprotein translocase tigerfam: preprotein translocase most propable TMH: 2 no signal peptide InterPro: Preprotein translocase SecG subunit Pfam: secG: preprotein translocase SecG subuni; High confidence in function and specificity
YP_932900.1	NADH-ubiquinone oxidoreductase chain 3 (EC 1.6.5.3). Ndh-1 shuttles electrons from nadh, via fmn and iron- sulfur (fe-s) centers, to quinones in the respiratory chain. the immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (by similarity).; High confidence in function and specificity
YP_932901.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_932902.1	Catalyzes the transfer of electrons from NADH to quinone
YP_932903.1	Catalyzes the transfer of electrons from NADH to quinone
YP_932904.1	Catalyzes the transfer of electrons from NADH to quinone
YP_932905.1	NADH-quinone oxidoreductase chain F (EC 1.6.99.5) (NADH dehydrogenase I chain F) (NDH-1 chain F). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit gnd_rel: 6-phosphogluconate dehydrogenas; High confidence in function and specificity
YP_932906.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_932907.1	NADH-quinone oxidoreductase chain H (EC 1.6.99.5) (NADH dehydrogenase I chain H) (NDH-1 chain H). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient (By similarity). InterPro: Respiratory-chain NADH dehydrogenase subunit 1 nup: nucleoside transporter; High confidence in function and specificity
YP_932908.1	Catalyzes the transfer of electrons from NADH to quinone
YP_932909.1	NADH-quinone oxidoreductase chain J (EC 1.6.99.5) (NADH dehydrogenase I chain J) (NDH-1 chain J). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient. MIP: MIP family channel proteins; High confidence in function and specificity
YP_932910.1	Catalyzes the transfer of electrons from NADH to quinone
YP_932911.1	NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH dehydrogenase I chain L) (NDH-1 chain L). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient (By similarity). 2A0310: amino acid permease (yeast); High confidence in function and specificity
YP_932912.1	Catalyzes the transfer of electrons from NADH to quinone
YP_932913.1	Catalyzes the transfer of electrons from NADH to quinone
YP_932914.1	ADPribose diphosphatase. ACTIVE ON ADENOSINE(5)TRIPHOSPHO(5)ADENOSINE (AP3A) ADP-RIBOSE NADH ADENOSINE(5)DIPHOSPHO(5)ADENOSINE (AP2A). InterPro: NUDIX hydrolase TIGR00052: conserved hypothetical protein.; High confidence in function and specificity
YP_932915.1	Conserved hypothetical ribonucleoside reductase. Homology to nrdE of C. violaceum of 62% (trembl|Q7NY29). Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides precursors that are necessary for DNA synthesis (By similarity). InterPro: Ribonucleotide reductase large subunit (IPR000788) Pfam: Ribonucleotide reductase, all-alpha domein; Ribonucleotide reductase, barrel domain no signal peptide no TMHs; High confidence in function and specificity
YP_932916.1	Probable hydrogen dehydrogenase, alpha subunit. Homology to hoxF of A. eutrophus of 41% (sprot|HOXF_ALCEU). SUBUNITS ALPHA AND GAMMA OF HOXS CONSTITUTE AN NADH-OXIDOREDUCTASE. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit (IPR001949); Respiratory-chain NADH dehydrogenase 24 Kd subunit (IPR002023) Pfam: Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit no signal peptide no TMHs; High confidence in function and specificity
YP_932917.1	Probable hydrogen dehydrogenase, gamma subunit. Homology to hoxU of A. eutrophus of 40% (pir|B35385(PIR). Binds 3 4Fe-4S clusters per subunit (Potential). Pfam: 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_932918.1	Probable hydrogen dehydrogenase, delta subunit. Homology to hoxY of a. eutrophus of 45% (sprot|HOXY_ALCEU). InterPro: Respiratory-chain NADH dehydrogenase 20 Kd subunit Pfam: NADH ubiquinone oxidoreductase, 20 kD subunit no signal peptie no TMHs; High confidence in function and specificity
YP_932919.1	Probable hydrogen dehydrogenase, beta subunit. Homology to hoxH of a. eutrophus of 48% (sprot|HOXH_ALCEU). Pfam: Nickel-dependent hydrogenase no signal peptide no TMHs; High confidence in function and specificity
YP_932920.1	conserved hypothetical protein. Homology to an orf of R. capsulata of 42% (trembl|Q9XBW7). Tigrfam: hycI: hydrogenase maturation protease no signal peptide no TMHs
YP_932921.1	Conserved hypothetical protein. Homology to GSU0904 of Geobacter sulfurreducens of 31% (gnl|keqq|gsu:GSU0904(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_932922.1	CzcD: Members of this family are integral membrane proteins that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells. 41% Cation_efflux. Pfam:PF01545; Cation_efflux; 1. TMhelix:6.; High confidence in function and specificity
YP_932923.1	Conserved hypothetical protein. Homology to Rsc1208 of R. solanacearum of 45% (trembl|Q8Y036). InterPro: AP endonucleases family 1 (IPR000097) tigrfam: xth: exodeoxyribonuclease III (xth) All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Pfam: AP endonuclease family 1 no signal peptide no TMHs
YP_932924.1	Conserved hypothetical membrane protein. Homology to CV3790 of Chromobacterium violaceum of 42% (trembl|Q7NRJ1). No domains predicted. no signal peptide 5 TMHs; Conserved hypothetical protein
YP_932925.1	TREMBLNEW:CAE27009: Probable carboxylesterase, 50% identity, 60% similarity. Dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) (Acetoin dehydrogenase E2 component). InterPro: Alpha/beta hydrolase fold: IPR000073; A/b_hydrolase. IPR003089; AB_hydrolase. IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1 InterPro: Alpha/beta hydrolase fold kdgT: 2-keto-3-deoxygluconate permease; Family membership
YP_932926.1	catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
YP_932927.1	Conserved hypothetical protein. Homology to bsr7110 of B.japonicum of 48% (tremble:Q89EH5). Pfam:Protein of unknown function (DUF465) Family members are found in small bacterial proteins, and also in the heavy chains of eukaryotic myosin and kinesin, C terminal of the motor domain (Myosin Myosin_head, Kinesin Kinesin). Members of this family may form coiled coil structures. No signal peptide present. No TMH
YP_932928.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_932929.1	molecular chaperone
YP_932930.1	Chloride channel protein, yadQ.In E.coli the product of yadQ gene is named EriC.This family of ion channels contains 10 or 12 transmembrane helices. Each protein forms a single pore. It has been shown that some members of this family form homodimers. These proteins contain two CBS domains. Voltage-gated ClC-type chloride channel clcA. Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation as part of the extreme acid resistance (XAR) response (By similarity).; High confidence in function and specificity
YP_932931.1	Putative MarR-family transcriptional regulator,; Family membership
YP_932932.1	Conserved hypothetical flavoprotein. Homology to rsc2212 of P. solanacearum of 59% (trembl|Q8XXA4). Pfam: Methallo-beta-lactamase no signal peptide no TMHs; Conserved hypothetical protein
YP_932933.1	Conserved hypothetical protein, 63% Identitcal (77% similarity) to TrEMBL;Q8Y0P7,65% identity to TrEMBL;Q7WCK6. Most good homologous hits do not have the same VWA domain represented by this. Has PF05762(IPR008912):VWA domain containing CoxE-like protein;This family is annotated by SMART as containing a VWA type domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria. No Signal peptide or TMH reported present.; Function unclear
YP_932934.1	Conserved hypothetical secreted protein. Homology to TdenA01001626 of Thiobacillus denitrificans of 32% (gi|52006684|ref|ZP_00334063.1|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide. no TMHs; Conserved hypothetical protein
YP_932935.1	TREMBL: Q8Y0P5 : 81% identity, 90% similarity. Probable Cell division protein ftsH homolog (EC 3.4.24.-). InterPro:IPR003593; AAA_ATPase. IPR003959; AAA_ATPase_centr. Pfam: PF00004; AAA; ATPase family associated with various SMART: SM00382; AAA; Absence of transmembrane helices (TMHMM predicted) NON secretory protein ruvB: Holliday junction DNA helicase Ru; Specificity unclear
YP_932936.1	Conserved hypothetical cytochrome c-type protein. Homology to rsc0999 of R. solanacearum of 62% (trembl|Q8Y0P4). Pfam: Cytochrome c signal peptide no TMHs; Conserved hypothetical protein
YP_932937.1	Conserved hypothetical cytochrome c-type protein. Homology to ebA4874 of Azoarcus_EbN1 of 60% (gnl|keqq|eba:ebA4874(KEGG)). Interpro: cytochrome c,classI (IPRoo3088); cytochrome c, class IC (IPR008168). Pfam: cytochrome C. singal peptide. no TMHs; Conserved hypothetical protein
YP_932938.1	Hypothetical protein similar by 78% to RSc1001 [RS04291] [Ralstonia solanacearum(Pseudomonas solanacearum)].TrEMBL Q8Y0P2. No Signal Peptide Reported No TMH Reported.
YP_932939.1	Endonuclease III . Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines thymines and guanines. Acts on a damaged strand 5 from the damaged site (By similarity). TIGRFAM: comE: comEA protein; High confidence in function and specificity
YP_932940.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
YP_932941.1	Putative electron transport complex protein rnfG. Homolog to rnfG of R. capsulata of 36% (sprot|RNFG_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. signal peptide no TMHs; High confidence in function and specificity
YP_932942.1	Putative electron transport complex protein rnfD. Homology to rnfD of R. capsulatus of 33% (sprot|RNFD_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity). InterPro: NQR2 and RnfD/E related proteins (IPR004338) Pfam: NQR2, RnfD, RnfE family signal peptide probable 6 TMHs; Family membership
YP_932943.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_932944.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_932945.1	Probable electron transport complex protein RnfA. Homology to rnfA of R. capsultatus of 57% (RNFA_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Required for stable existence of rnfB and rnfC. InterPro: RnfA-Nqr electron transport subunit (IPR003667) Pfam: Rnf-Nqr subunit, membrane protein no signal peptide 6 TMHs; High confidence in function and specificity
YP_932946.1	HNH family of nucleases is found in bacteria,viruses, eukaryotes and includes yeast intron 1 protein,MutS, and bacterial colicins and pyocins. InterPro (IPR003615): HNH nuclease InterPro (IPR002711): HNH endonuclease. Pfam (PF01844): HNH endonuclease.; Family membership
YP_932947.1	Conserved hypothetical NUDIX hydrolase. Homology to ne1158 of N. europaea of 58% (trembl|Q82VD6) The generic name 'NUDIX hydrolases' (NUcleoside DIphosphate linked to some other moiety X) has been coined for this domain family. The family can be divided into a number of subgroups, of which MutT anti-mutagenic activity represents only one type; most of the rest hydrolyse diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). InterPro: NUDIX hydrolase (IPR000086) Pfam: MutT-like domain no signal peptide no TMHs; Function unclear
YP_932948.1	Probable response regulator,; Family membership
YP_932949.1	EAL/GGDEF-domain containing signaling protein,; Conserved hypothetical protein
YP_932950.1	Flagellar transcriptional activator,flhD. This family consists of several bacterial flagellar transcriptional activator proteins. FlhD combines with FlhC to form a regulatory complex in Escherichia coli. This complex has been shown to be a global regulator involved in many cellular processes as well as a flagellar transcriptional activator TrEMBL: Q82SD3 InterPro:IPR007911 Pfam:PF05247 FUNCTION: Transcriptional activator. Involved in the regulation of a number of genetic systems (By similarity). SUBUNIT: Homodimer; disulfide-linked. Forms a heterotetrameric complex with two subunits of flhC (By similarity). SUBCELLULAR LOCATION: Cytoplasmic (By similarity). Belongs to the flhD family. No Signal Peptide. No TMH Present.; Family membership
YP_932951.1	with FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems
YP_932952.1	Flagellar motor protein MotA (Chemotaxis motA protein). Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity). signal peptide probable 4 TMHs; High confidence in function and specificity
YP_932953.1	Flagellar motor protein MotB (Chemotaxis motB protein. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall. Pfam: OmpA family no signal peptide probable 1 TMHs; High confidence in function and specificity
YP_932954.1	Putative chemotaxis response regulator,; Family membership
YP_932955.1	Chemotaxis protein cheA; INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY. EMBL AE005411; AAG56878.1; -. AP002559; BAB36021.1; -. PIR B85802; B85802. F90953; F90953. InterPro IPR003594; ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR000629; DEAD_box. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR009082; His_kin_homodim. IPR008207; Hpt. IPR008208; Hpt_N. Pfam PF01584; CheW; 1. PF02895; H-kinase_dim; 1. PF02518; HATPase_c; 1. PF01627; Hpt; 1. PRINTS PR00344; BCTRLSENSOR.; High confidence in function and specificity
YP_932956.1	Positive regulator of CheA protein activity,; High confidence in function and specificity
YP_932957.1	The Escherichia coli chemoreceptor Tsr mediates tactic responses to serine, repellents, and changes in temperature. Similar to sprot|MCP1_ECOLI (31%)and to trembl|Q7NSI6 (36%). Bacterial chemotactic-signal transducers are proteins that respond to changes in the concentration of attractants and repellents in the environment, and transduce a signal from the outside to the inside of the cell. These proteins undergo two covalent modifications: deamidation and reversible methylation. Attractants increase the level of methylation while repellents decrease it. The methyl groups are added by the methyl-transferase cheR and are removed by the methylesterase cheB. Pfam (PF00015): MCPsignal TMHMM reporting two TMH.; Specificity unclear
YP_932958.1	Salmonella typhimurium shows an attractant response to citrate and a repellent response to phenol, and a chemoreceptor mediating these responses has been identified and named Tcp (taxis to citrate and away from phenol). Similar to sprot|MCPC_SALTY (32%)and to trembl|Q82TM2. InterPro (IPR004089): Bacterial chemotaxis sensory transducer InterPro (IPR003660): HAMP InterPro (IPR004090): Methyl-accepting chemotaxis protein InterPro (IPR001610): PAC InterPro (IPR000014): PAS_domain Pfam (PF00672): HAMP Pfam (PF00015): MCPsignal Pfam (PF00785): PAC Pfam (PF00989):PAS TIGRFAMs (TIGR00229): sensory_box TMHMM reporting two TMH.; Specificity unclear
YP_932959.1	Methylase of chemotaxis methyl-accepting proteins,; High confidence in function and specificity
YP_932960.1	Chemotaxis response regulator protein-glutamate methylesterase, catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by cheR.; High confidence in function and specificity
YP_932961.1	Methyl-accepting chemotaxis protein,; Specificity unclear
YP_932962.1	Probable chemotaxis protein, CheW. IPR001789; Response_reg. Pfam: PF01584; CheW. PF00072; Response_reg. SMART: SM00260; CheW. SM00448; REC. Chemotaxis protein cheV. CHEMOTAXIS INVOLVES BOTH A PHOSPHORYLATION-DEPENDENT EXCITATION AND A METHYLATION-DEPENDENT ADAPTATION. CHEV AND CHEW FUNCTION TOGETHER TO COUPLE CHEA ACTIVATION TO METHYL-ACCEPTING CHEMOTAXIS PROTEIN RECEPTOR STATUS AND POSSIBLE CHEA-DEPENDENT PHOSPHORYLATION OF CHEV CONTRIBUTES TO ADAPTATION.; High confidence in function and specificity
YP_932963.1	Probable chemotaxis protein, CheW. IPR001789; Response_reg. Pfam: PF01584; CheW. PF00072; Response_reg. SMART: SM00260; CheW. SM00448; REC. Chemotaxis protein cheV. CHEMOTAXIS INVOLVES BOTH A PHOSPHORYLATION-DEPENDENT EXCITATION AND A METHYLATION-DEPENDENT ADAPTATION. CHEV AND CHEW FUNCTION TOGETHER TO COUPLE CHEA ACTIVATION TO METHYL-ACCEPTING CHEMOTAXIS PROTEIN RECEPTOR STATUS AND POSSIBLE CHEA-DEPENDENT PHOSPHORYLATION OF CHEV CONTRIBUTES TO ADAPTATION.; High confidence in function and specificity
YP_932964.1	Chemotaxis response regulator, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. Chemotaxis protein cheY. Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form cheY exhibits enhanced binding to a switch component fliM at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity).; High confidence in function and specificity
YP_932965.1	cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation
YP_932966.1	Chemotaxis histidine kinase,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. Chemotaxis protein cheA (EC 2.7.3.-). INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY.; High confidence in function and specificity
YP_932967.1	Hypothetical protein, 31% identity (47% similarity) to TrEMBL:Q8KLF6 Coils2 program reports the presence of coiled-coil.
YP_932968.1	catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate
YP_932969.1	tRNA pseudouridine synthase C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; High confidence in function and specificity; ORF3
YP_932970.1	SodB: Superoxide dismutase [Fe] (EC 1.15.1.1).Catalyse the conversion of superoxide radicals to molecular oxygen. Their function is to destroy the radicals that are normally produced within cells and are toxic to biological systems. 76% SODismutase. Pfam:PF02777; Sod_Fe_C; 1. PF00081; Sod_Fe_N; 1.; High confidence in function and specificity
YP_932971.1	Probable exodeoxyribonuclease VII large subunit . Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides which are then degraded further into small acid-soluble oligonucleotides (By similarity). TIGRFAM: xseA: exodeoxyribonuclease VII large.; High confidence in function and specificity
YP_932972.1	conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership
YP_932973.1	Putative biopolymer transport exbD2 protein. Homology to exbD2 of V. choloera of 31% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership
YP_932974.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
YP_932975.1	Putative inner membrane protein [ycaR], 66% identity (85% similarity) to SwissProt;P75844(E.coli) and 65% identity to TrEMBL;Q7CQT7. Has PF03966:Protein of unknown function (DUF343);This family of short proteins have no known function. The bacterial members are about 60-70 amino acids in length and the eukaryotic examples are about 120 amino acids in length. The C terminus contains the strongest conservation. Signal Peptide or TMH not present.; Function unclear
YP_932976.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_932977.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_932978.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_932979.1	Gamma-glutamyltranspeptidase catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. Similar to trembl|Q88H30 (43%)and to trembl|Q8UJH0 (36%). TIGRfam (TIGR00066): Gamma-glutamyltranspeptidase Pfam (PF01019): Gamma-glutamyltranspeptidase SignalP reporting Signal peptide.; Specificity unclear
YP_932980.1	Conserved hypothetical membrane protein,; Conserved hypothetical protein
YP_932981.1	Putative NAD(P)H oxidoreductase HI1544 (EC 1.6.5.2 ). trembl:Q88J60: 64% identity; 80% similarity This family consists of bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC: 1.6.5.2 that catalyses the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species [1]. This enzyme uses a FAD co-factor InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavodoxin_2 SignalP predicted signal peptide present No transmembrane helices (TMHMM predicted); High confidence in function and specificity
YP_932982.1	Probable MerR-family transcriptional regulator,; Family membership
YP_932983.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_932984.1	Probable Nitrogen regulatory protein P-II 1. Could be involved in the regulation of nitrogen fixation.Belongs to the P(II) protein family.55% similarity with Methanothermobacter thermautotrophicus,TrEMBL:O26758 Pfam:PF00543, InterPro:IPR002332,IPR002187 No Signal peptide present. No TMH reported.
YP_932985.1	Conserved hypothetical membrane protein. Homology to ttc139 of T. termophilus of 49% (trembl|Q72LC0). no domains no singal peptide 8 TMHs; Conserved hypothetical protein
YP_932986.1	catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules
YP_932987.1	Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its activity. Has PF00149,Calcineurin-like phosphoesterase; IPR004843, M-pesterase; This family includes a diverse range of phosphoesterases,including protein phosphoserine phosphatases,nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD P13457 or yeast MRE11 P32829. The most conserved regions in this superfamily centre around the metal chelating residues.; High confidence in function and specificity
YP_932988.1	Putative extracellular nuclease. Homology to nucH of A. hydrophila of 33% (trembl|Q44070) Tigrfam: xth: exodeoxyribonuclease III (xth) Pfam: Endonuclease/ Exonuclease/ Phoshatase family singal peptide no TMHs; Family membership
YP_932989.1	Conserved hypothetical membrane protein. Homology ebA4071 of Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA4071(KEGG)). Has PF06930, Protein of unknown function (DUF1282); IPR009698; This family consists of several hypothetical proteins of around 200 residues in length. The function of this family is unknown although a number of family members are thought to be putative membrane proteins. no signal peptide. 5 TMHs; Conserved hypothetical protein
YP_932990.1	Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_932991.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_932992.1	Conserved hypothetical protein. Homology to Daro03003756 of Dechloromonas aromatica of 53% (gi|41722684|ref|ZP_00149673.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_932993.1	Hypothetical protein CT2219. SPROT:Q8KAE4: 65% identity; 78% similarity. TREMBL:Q7NS63: 60% identity, 72% similarity putative ACR related to the C-terminal domain of histone macroH2A1 This domain is found in a number of protein associated with DNA and/or RNA unwinding InterPro; IPR002589; A1pp. Pfam; PF01661; A1pp; 1. SMART; SM00506; A1pp non-secretory protein with no signal peptide (SignalP predicted). No transmembrane helices (TMHMM predicted); Function unclear
YP_932994.1	Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein
YP_932995.1	Probable polar differentiation response regulator,; Family membership
YP_932996.1	Putative histidine protein kinase,; Specificity unclear
YP_932997.1	Conserved hypothetical membrane protein. Homology to Avar03001212 of Anabaena variabilis of 34% (gi|53765559|ref|ZP_00161954.2|(NBCI ENTREZ)). Pfam: Peptidase family M48. 2 TMHs. no signal peptide; Conserved hypothetical protein
YP_932998.1	Similarity to hypothetical protein in C. violaceum.
YP_932999.1	Conserved hypothetical protein. Homology to CV0860 of Chromobacterium violaceum of 50% (trembl: Q7NZR1). No domains predicted. No TMHs. No signal peptide.
YP_933000.1	Conserved Hypothetical protein Signal Peptide present. Has Prosite PS00380; RHODANESE_1; Rhodanese (thiosulfate sulfurtransferase) (EC 2.8.1.1)is an enzyme which catalyzes the transfer of the sulfane atom of thiosulfate to cyanide, to form sulfite and thiocyanate. In vertebrates, rhodanese is a mitochondrial enzyme of about 300 amino-acid residues involved in forming iron-sulfur complexes and cyanide detoxification. A cysteine residue takes part in the catalytic mechanism.
YP_933001.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_933002.1	Conserved hypothetical membrane protein Homology to an orf of C. violaceum of 41% (trembl|Q7NSF3(SRS)) No domains predicted Signal Peptide present. TMHMM2 reporting 2 TMH's present.; Conserved hypothetical protein
YP_933003.1	TREMBL:Q8XSIO: 58% identity, 73% similarity Hypothetical HIT-like protein Rv0759c/MT0784/Mb0782c. InterPro:IPR001310; HIT. Pfam: PF01230; HIT; 1. PRINTS: PR00332; HISTRIAD InterPro: HIT (Histidine triad) family hupD: hydrogenase expression/formation pr; Family membership
YP_933004.1	Hypothetical secreted protein. Weak homology with hits in the database. Signal Peptide present. No domains predicted. No TMHs
YP_933005.1	Hypothetical protein. No homology to the data bank. Has 2 copies of SMART;SM00671, SEL1, Sel1-like repeats.These represent a subfamily of TPR (tetratricopeptide repeat) sequences. No TMHs. No signal peptide.
YP_933006.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 3 TMHs
YP_933007.1	Putative two-component response regulator,; Family membership
YP_933008.1	Putative two-component sensor histidine kinase,; Specificity unclear
YP_933009.1	Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-). SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE. REQUIRED FOR MANY TYPES OF RECOMBINATIONAL EVENTS ALTHOUGH THE STRINGENCY OF THE REQUIREMENT FOR RECJ APPEARS TO VARY WITH THE TYPE OF RECOMBINATIONAL EVENT MONITORED AND THE OTHER RECOMBINATION GENE PRODUCTS WHICH ARE AVAILABLE. InterPro: Single-stranded-DNA-specific exonuclease RecJ. recJ: single-stranded-DNA-specific exo.; High confidence in function and specificity
YP_933010.1	Conserved hypothetical protein. Homology to CV2476 of C.violaceum of 38% (tremble:Q7NV68) No domains predicted. No signal peptide or TMH present.
YP_933011.1	Conserved hypothetical protein. Homology to cv1738 of C. violaceum (sprot|YH38_CHRVO) InterPro: Uncharacterized protein family UPF0004 (IPR005839) no signal peptide no TMHs TIGR00089: conserved hypothetical prote
YP_933012.1	Hypothetical membrane protein. No homology to the data bank. No domaine predicted. No signal peptide. 2 TMHs
YP_933013.1	Putative lipoprotein transporter permease. Homology to lolE of E. coli of 36% (sprot|LOLE_ECOLI). Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of lolA (By similarity). Pfam: Predicted permease signal peptide 3 TMHs; High confidence in function and specificity
YP_933014.1	Lipoprotein releasing system ATP-binding protein lolD. Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of lolA. Similar to TREMBL:Q82VL9; TREMBL:Q8Y0C6; SWISSPROT:P75957 (58% identity). Pfam (PF00005): ABC transporter. TC (3.A.1.125): The Lipoprotein Translocase (LPT) Family.; High confidence in function and specificity
YP_933015.1	Conserved hypothetical membrane protein. Homology to ne0829 of N. europaea of 46% (trembl|Q82W66(SRS)) No domains predicted No signal peptide 4 TMHs; Conserved hypothetical protein
YP_933016.1	Competence protein comA. Essential for natural transformation. Could be a transporter involved in DNA uptake. InterPro: DNA internalization-related competence protein ComEC/Rec2 function: transporter activity TREMBL:Q82SD2: 38% identity,50% similarity. InterPro:IPR001279; Blactmase-like. IPR004477; ComEC_N-term. IPR004797; ComEC_Rec2. Pfam PF03772; Competence; 1. PF00753; Lactamase_B; 1. TIGRFAMs:TIGR00360; ComEC_N-term; 1. TIGR00361; ComEC_Rec2; ComEC_Rec2: DNA internalization-relate TMHMM predicted 8 transmembrane helices; High confidence in function and specificity
YP_933017.1	TREMBL:Q8XZ32: 54% identity, 66% similarity Probable Hypothetical protein Rv2715/MT2788/Mb2734. InterPro:IPR000073; A/b_hydrolase. IPR003089; AB_hydrolase. IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 InterPro: Alpha/beta hydrolase fold Mtu_fam_11: Mycobacterium tuberculosis pa; Family membership
YP_933018.1	Conserved hypothetical protein. Homology to RS04633 of R.solanacearum of 73% (tremble:Q8Y0C3). Has PF04169(IPR007297);Domain of unknown function (DUF404);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF407 (IPR007302). Has PF04174;Domain of unknown function (DUF407);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF404 (IPR007297). No signal Peptide or TMH present.
YP_933019.1	Conserved Hypothetical protein, 57% identity to TrEMBL;Q8Y0C2 Has PF04168;(IPR00729)Bacterial domain of unknown function (DUF403):This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF404 (IPR007297) and DUF407 (IPR007302). No Signal peptide or TMH reported Present.; Function unclear
YP_933020.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_933021.1	Putative metalloprotease. Homology to ste24 of S. cerevisiae of 32% (sprot|ST24_YEAST). CAAX prenyl protease 1 (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (PPSEP 1) (A-factor converting enzyme). Proteolytically removes the C-terminal three residues of farnesylated A-factor mating pheromone. Also acts to cleave the N-terminal extension of the pheromone. probable signal peptide probable 7 TMHs; Family membership
YP_933022.1	3'-5' exoribonuclease specific for small oligoribonuclotides
YP_933023.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_933024.1	Conserved hypothetical membrane protein. Homology to CV1748 of C. violaceum of 32% (trembl|Q7NX80(SRS)). No domains predicted. No signal peptide 11 TMHs; Conserved hypothetical protein
YP_933025.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_933026.1	putative TIM-barrel protein; Specificity unclear
YP_933027.1	tRNA (guanine-N(7)-)-methyltransferase, 29% identity to SwissProt;Q8EBX8. SwissProt;Q8Y1I7(25% Identity),Q8FE22(25% identity). Has PF02390,Methyltransf_4,Putative methyltransferase;IPR003358; This is a family of putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity.
YP_933028.1	Conserved hypothetical protein. Homology to ct227 of C. tepidum of 32% (trembl|Q8KA93). Pfam: SEC-C motif This motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain. no TMHs
YP_933029.1	Conserved hypothetical protein. Homology to PA3209 of Pseudomonas aeruginosa of 43% (trembl:Q9HZ31). Has PF03692, Uncharacterised protein family (UPF0153); IPR005358;This family of proteins contain 8 conserved cysteines that may form a metal binding site. The function of these proteins is unknown but might be an Fe-S cluster as part of an oxidoreductase complex. No signal peptide. No TMHs
YP_933030.1	TREMBL:Q8XH16: 56% identity, 66% similarity. SPROT:P71300: 53% identity, 67% similarity Hypothetical protein ykgJ; This family of proteins contain 8 conserved cysteines that may form a zinc binding site. The function of these proteins is unknown InterPro:IPR005358; UPF0153. Pfam: PF03692; UPF0153 No signal peptide. No transmembrane helices; High confidence in function and specificity
YP_933031.1	Function unclear
YP_933032.1	Conserved hypothetical protein. Homology to XAC2816 of Xanthomonas axonopodis of 52% (trembl:Q8PIS9). No domains predicted. No TMHs. No signal peptide.
YP_933033.1	42% K+channel_pore.IPR003148; TrkA_N. Pfam:PF02254; TrkA_N; 2. TMhelix:3; Function unclear
YP_933034.1	Conserved hypothetical membrane protein. Homology to AQ_302 of Aquifex aeolicus of 38% (trembl|O66649). No domains predicted. No signal peptide 4 TMHs; Conserved hypothetical protein
YP_933035.1	Hypothetical secreted protein. Weak homology with hits in the database. Signal Peptide present. No TMHs. No domains predicted
YP_933036.1	Hypothetical protein, 65% Identity (77% similarity) to SwissProt; Q7NS67.56% identity to SwissProt;Q8Y2R5. No domains, repeats, motifs or features present.
YP_933037.1	Catalyzes the conversion of citrate to isocitrate
YP_933038.1	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
YP_933039.1	Conserved hypothetical signaling protein. Homology to ebA3785 of Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebA3785(KEGG)). Pfam: PF00990 GGDEF domain. PF01590 GAF domain. PF00563 EAL domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_933040.1	Conserved hypothetical secreted protein. Homology to bd2668 of B. bacteriovorus of 53% (tremblnew|CAE80459). no domains signal peptide no TMHs; Conserved hypothetical protein
YP_933041.1	Conserved hypothetical protein. Homology to Raeut03004638 of Ralstonia eutropha of 37% (gi|45515835|ref|ZP_00167389.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_933042.1	Putative phosphoenolpyruvate-protein phosphotransferase,; Function unclear
YP_933043.1	Putative acetoin dehydrogenase, alpha subunit. Homology to acoA of C. magnum of 36% (trembl|Q46142) CATALYZES THE 26-DICHLOROPHENOLINDOPHENOL-DEPENDENT CLEAVAGE OF ACETOIN INTO ACETATE AND ACETALDEHYDE IN VITRO. THE ALPHA SUBUNIT IS PROBABLY THE CATALYTIC SUBUNIT OF THE ENZYME. Pfam: Dehydrogenase E1 component no signal peptide no TMHs; Family membership
YP_933044.1	Probable acetoin dehydrogenase, beta subunit. Homology to acoB of A. eutrophus of 41% (sprot|ACOB_ALCEU) Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde, in vitro. The beta subunit is probably not the catalytic subunit of the enzyme. Pfam: Transketolase, pyridine binding; Transketolase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity
YP_933045.1	Putative glutathione transferase. Homology to gst of E. coli of 36% (sprot|GT_ECOLI). Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. InterPro: Glutathione S-transferase C terminus (IPR004046); Glutathione S-transferase N terminus (IPR004045) Pfam: Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal no signal peptide no TMHs; High confidence in function and specificity
YP_933046.1	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Homolog to E. coli ynfM, an hypothetical transport protein,probably involved in antibiotic resistance. InterPro: General substrate transporters 2A0108: nitrate transporter; High confidence in function and specificity
YP_933047.1	Transcriptional regulator, LysR family,; Specificity unclear
YP_933048.1	GGDEF/EAL/PAC/PAS-domain containing protein, sym; pNGR234a) / TREMBL: trembl|Q88A61 (38% Pseudomonas syringae (pv. tomato), sensory box/ggdef domain/eal domain protein pspto0536) InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain.; Conserved hypothetical protein
YP_933049.1	Hypotheical protein. No good homology of the entire protein with the data base. No domains predicted. No THs. No signal peptide.
YP_933050.1	Probable Citrate lyase beta chain(EC 4.1.3.6)(Citrase)(Citryl-CoA lyase subunit)(EC 4.1.3.34). In citrate-utilising prokaryotes, citrate lyase cleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha,beta, and gamma subunits.The alpha subunit substitutes citryl for the acetyl group to form citryl-S-ACP. The beta subunit completes the reaction by cleaving the citryl to yield oxaloacetate and (regenerated) acetyl-S-ACP. Similar to the CitE protein from L.mesenteroides where is part of a gene cluster citCDEFG. SWISSPROT:CILB_LEUMC.O53078. InterPro:IPR006475; CitE.IPR001465; Malate_synthase. TIGRFAMs:TIGR01588; citE; 1.; Function unclear
YP_933051.1	catalyzes the oxidation of malate to oxaloacetate
YP_933052.1	Putative GntR-family transcriptional regulator,; Family membership
YP_933053.1	Succinate dehydrogenase cytochrome b-556 subunit,sdhC.58% Identity to TrEMBL;Q7NZ57.52% to TrEMBL;Q9JRJ0,36% to SwissProt;P10446. Has PF01127,Succinate dehydrogenase cytochrome b subunit;IPR000701 Sdh_cyt; Succinate dehydrogenase (SDH) is a membrane-bound complex of two main components: a membrane-extrinsic component composed of an FAD-binding flavoprotein and an iron-sulphur protein, and a hydrophobic component composed of a cytochrome b and a membrane anchor protein.The cytochrome b component is a mono heme transmembrane protein belonging to a family that includes cytochrome b-556 from bacterial SDH (gene sdhC); cytochrome b560 from the mammalian mitochondrial SDH complex and that encoded in the mitochondrial genome of some algae and in the plant Marchantia polymorpha; cytochrome b from yeast mitochondrial SDH complex (gene SDH3 or CYB3); and protein cyt-1 from Caenorhabditis. These cytochromes are proteins of about 130 residues that comprise three transmembrane regions. There are two conserved histidines which may be involved in binding the heme group.
YP_933054.1	Succinate dehydrogenase, hydrophobic membrane anchor subunit. Homology to sdhD of C. burnetii of 41% (sprot|DHSD_COXBU). THIS IS THE HYDROPHOBIC COMPONENT OF THE SUCCINATE DEHYDROGENASE COMPLEX. IT IS SUGGESTED THAT IT IS REQUIRED TO ANCHOR THE CATALYTIC COMPONENTS TO THE CYTOPLASMIC MEMBRANE. no signal peptide 3 TMHS; Family membership
YP_933055.1	Probable succinate dehydrogenase, flavoprotein subunit. Homology to sdhA of C. burnetii of 54% (sprot|DHSA_COXBU) Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein,cytochrome b-556 and a hydrophobic protein. CATALYTIC ACTIVITY: Succinate + acceptor = fumarate + reduced acceptor. InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal (IPR003953); Fumarate reductase/succinate dehydrogenase FAD-binding site (IPR003952); Fumarate reductase/succinate dehydrogenase, C-terminal (IPR004112) Pfam: FAD-binding domain; Fumarate reductase/succinate dehydrogenase no TMHs no signal peptide gidA: glucose-inhibited division prot; High confidence in function and specificity
YP_933056.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_933057.1	Conserved hypothetical protein, 39% identity to Swissprot;Q46825, ygfY of Escherichia coli. Has PF03937:(IPR005631, DUF339)TPR repeat region;This family represents a set of three divergent TPR repeats found in a small group of uncharacterised proteins. No Signal Peptide or TMH present.; Family membership
YP_933058.1	Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity
YP_933059.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_933060.1	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA
YP_933061.1	E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_933062.1	conserved hypothetical protein but a part of protein have similarity to potassium-transporting ATPase,A subunit. TIGR Cellular role(s):Transport and binding proteins: Cations Entry name :- SWISSPROT:YACK_RHIME Prim. accession # Q9X447 Identity:-46% interPro :-IPR004623; K_ATPaseA. Pfam PF03814; KdpA; 1. Number of predicted TMHs: 0 Signal peptide probability: 0.082
YP_933063.1	Hypothetical protein yhcM. TREMBL:Q8XZX3: 54% identity, 69% similarity This family of proteins contains a P-loop motif and are predicted to be ATPases InterPro:IPR005654; AFG1_ATPase. Pfam PF03969; AFG1_ATPase No signal peptide No transmembrane helices L9: ribosomal protein L9; Specificity unclear
YP_933064.1	Probable ATP-dependent helicase,; Family membership
YP_933065.1	Molybdopterin-guanine dinucleotide biosynthesis protein B. may bind the guanine nucleotide required for the synthesis of molybdopterin guanine dinucleotide. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity
YP_933066.1	Molybdopterin biosynthesis protein moeA. Involved in the biosynthesis of a demolybdo-cofactor (molybdopterin) necessary for molybdo-enzymes. Seems to be involved in a step of activation of molybdenum in the form of thiomolybdenum. InterPro: Molybdenum cofactor biosynthesis protein molyb_syn: molybdenum cofactor synthesis; High confidence in function and specificity
YP_933067.1	Molybdopterin converting factor subunit 1 (MPT synthase subunit 1) (Molybdopterin synthase subunit 1) (Molybdenum cofactor biosynthesis protein D) . Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur atoms are provided by the active form of the small subunit whose activation involves the acquisition of sulfur and the activity of moeB/chlN.; High confidence in function and specificity
YP_933068.1	Molybdopterin converting factor subunit 2 (MPT synthase subunit 2) (Molybdopterin synthase subunit 2) . Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.; High confidence in function and specificity
YP_933069.1	Putative phasin protein PhaP.A family of small proteins found associated with inclusions in bacterial cells. Most associate with polyhydroxyalkanoate (PHA) inclusions, the most common of which consist of polyhydroxybutyrate (PHB). These are designated granule-associate proteins or phasins. However, the member from Magnetospirillum sp. AMB-1 is called a magnetic particle membrane-specific GTPase. TrEMBL: Q93QF2 InterPro:IPR010127,TIGR01841 NO TMH Present No Signal Peptide Present; Family membership
YP_933070.1	Probable ATP-dependent Clp protease, ATP-binding subunit ClpB. Homology to clpB of E. coli of 66% (sprot|CLPB_ECOLI). The protein is thought to be subunits of ATP-dependent proteases which act as chaperones to target the proteases to substrates. Pfam: ATPase family assocciated with various cellular activities; CPL amino terminal domain no signal peptide no TMHs; High confidence in function and specificity
YP_933071.1	GGDEF/EAL-domain containing protein
YP_933072.1	Putative peptidyl-prolyl cis-trans isomerase. Homology to ppiD of E. coli of 23% (sprot|PPID_ECOLI). PPIASES ACCELERATE THE FOLDING OF PROTEINS. SEEMS TO BE INVOLVED IN THE FOLDING OF OUTER MEMBRANE PROTEINS. InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain probable 1 TMH no signal peptide; Family membership
YP_933073.1	CATALYTIC ACTIVITY: Acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH Entry name:- SWISSPROT:FABI_PSEAE Prim. accession # Q9ZFE4 Identities = 173/260 (66%) InterPro :- IPR002198; ADH_short. Pfam:- PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.044 Number of predicted TMHs: 0; High confidence in function and specificity
YP_933074.1	Conserved hypothetical membrane protein. Homology to RSC3414 of Ralstonia solanacearum of 48% (sprot|YY14_RALSO(SRS)), Has PF05249:(IPR007913);Uncharacterised protein family (UPF0187);This family of proteins is functionally uncharacterised. signal peptide 2 TMHs; Conserved hypothetical protein
YP_933075.1	Conserved hypothetical protein. Homology to hbpA of N. europaea of 56%. Protein consist of two domains: 1. bacterial extracellular sloute protein with homology to heme-binding protein A which is important for the heme aquisition and 2. a transmembrane helix a the C-terminus (unusual combination). Interpro: Bacterial extracellular solute-binding protein, family 5 (IPR000914) Pfam: Bacterial extracellular solute binding protein Signal peptide one TMH
YP_933076.1	Dipeptide transport system permease dppB. Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. InterPro: Binding-protein-dependent transport systems inner membrane component crcB: crcB protein; High confidence in function and specificity
YP_933077.1	Oligopeptide transport system permease appC. This protein is a component of an oligopeptide permease a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence though unlike OPP is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity). pts-Glc: PTS system maltose and gluco; High confidence in function and specificity
YP_933078.1	Conserved hypothetical protein. Homology to XCC2284 of X.campestris of 67% (tremble:Q8P8F8) Has PF02696;Uncharacterized ACR, YdiU/UPF0061 family(Protein of Unknown Function), IPR003846. No signal peptide. No TMHs
YP_933079.1	Probable NnrU protein, 31% identity to TrEMBL;Q92Z13, Q9AAA0 Has PF07298(IPR009915):NnrU protein;This family consists of several plant and bacterial NnrU proteins. NnrU is thought to be involved in the reduction of nitric oxide. The exact function of NnrU is unclear. It is thought however that NnrU and perhaps NnrT are required for expression of both nirK and nor
YP_933080.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_933081.1	Entry name TREMBL:Q8XZH0 Prim. accession # Q8XZH0 InterPro :- IPR005340; UPF0083. Pfam PF03654; ARPF; 1. Identities = 78/142 (54%), Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000
YP_933082.1	Conserved hypothetical protein. Homology to CV3462 of C.violaceum of 54% (tremble:Q7NSG4) Has PF03658;Uncharacterised protein family (UPF0125). IPR005346 Has no signal peptide or TMH present.
YP_933083.1	Conserved hypothetical secreted protein. Homology to RS05265 of R. solanacearum of 30% (trembl|Q8XZG8(SRS)) No domains predicted Signal peptide present No TMH reported.; Conserved hypothetical protein
YP_933084.1	IMP dehydrogenase (Inosine-5'-monophosphate dehydrogenase) (Inosinic acid dehydrogenase) (Inosinate dehydrogenase) (IMP oxidoreductase) (Inosine monophosphate oxidoreductase) kpsF: KpsF/GutQ family protein; High confidence in function and specificity
YP_933085.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_933086.1	HTH-type transcriptional activator,; Specificity unclear
YP_933087.1	NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (QR1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase). The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis (By similarity). trembl:Q9I4B4:72%identity; 81% similarity InterPro: NAD(P)H dehydrogenase (quinone) InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavodoxin_2 crcB: crcB protein No signal peptide present Absence of transmembrane helices (TMHMM predicted); High confidence in function and specificity
YP_933088.1	Putative two-component hybrid sensor and regulator ,; Function unclear
YP_933089.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 1 TMH
YP_933090.1	Conserved hypothetical secreted protein. Homology to Avin02003713 of Azotobacter vinelandii of 35% (gi|53610668|ref|ZP_00089587.2|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide present. No TMH present.; Conserved hypothetical protein
YP_933091.1	Putative two-component system sensor protein,; Function unclear
YP_933092.1	Cytidine deaminase (EC: 3.5.4.5) (cytidine aminohydrolase) catalyzes the hydrolysis of cytidine into uridine and ammonia while deoxycytidylate deaminase (EC: 3.5.4.12) (dCMP deaminase) hydrolyzes dCMP into dUMP. Both enzymes are known to bind zinc and to require it for their catalytic activity [1, 2]. These two enzymes do not share any sequence similarity with the exception of a region that contains three conserved histidine and cysteine residues which are thought to be involved in the binding of the catalytic zinc ion.; High confidence in function and specificity
YP_933093.1	Conserved hypothetical protein. Homology to CBU1080 of C.burnetii of 59% (tremble:Q83CN1) Has PF03734;ErfK/YbiS/YcfS/YnhG;(IPR005490)This family of proteins are found in a range of bacteria. Th conserved region contains a conserved histidine and cysteine,suggesting that these proteins have an enzymatic activity. Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate. No TMHs. No signal peptide.
YP_933094.1	Conserved hypothetical acetyltransferase. Homology to glr3404 of G. violaceus of 52% (trembl|Q7NFX1). InterPro: GCN5-related N-acetyltransferase (IPR000182) Pfam: Acetyltransferase (GNAT) family no signal peptide no TMHS; Family membership
YP_933095.1	Conserved hypothetical protein. Homology to GSU0792 of G.sulfurreducens of 50% (gsu:GSU0792(KEGG)) Has PF05742(IPR008551);Protein of unknown function (DUF833);This family is found in eukaryotes, prokaryotes and viruses and has no known function. P54797 has been found to be expressed during early embryogenesis in mice. No signal peptide or TMH present.
YP_933096.1	Conserved hypothetical protein. Homology to ebD92 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD92(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933097.1	Conserved hypothetical protein aminomethyltransferase . Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein; Specificity unclear
YP_933098.1	Hypothetical protein HI0457. This entry describes proteins of unknown function TREMBL:Q8XYH5: 50% identity,66% similarity InterPro:IPR003770; DUF175. Pfam:PF02618; ADC_lyas Non secretory protein with signal peptide probability 0.977 (Signal P predicted) No. of transmembrane helices: 1 (TMHMM predicted) This entry describes proteins of unknown function 2A0108: nitrate transporter; Function unclear
YP_933099.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_933100.1	DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime.; High confidence in function and specificity
YP_933101.1	Type IV pilus biogenesis protein PilZ, 56% identity to TrEMBL;Q87YH3, Q8PBU4. Has PF07238, Type IV pilus assembly protein PilZ; IPR009875 ;This family consists of several bacterial type IV pilus assembly proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown.
YP_933102.1	Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family.; Specificity unclear
YP_933103.1	Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro: Ankyrin-repeat Pfam:Phage_integr_N:Phage integrase, N-terminal SAM-like wecB_tagA_cpsF: glycosyl transferase. Transmembrane helices 0 and presence of signal peptide (Signal P)for exporting.(probably signal peptide bearing exported protein); Specificity unclear
YP_933104.1	Conserved hypothetical protein. Homology to Rgel02003216 of Rubrivivax gelatinosus of 54% (gi|47572589|ref|ZP_00242632.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_933105.1	Histone deacetylases catalyse the removal of the acetyl group from histones. Histone deacetylase, acetoin utilization proteins and acetylpolyamine amidohydrolases are all members of an ancient family, TREMBL:Q7NVL6 (58% identity); TREMBL:Q8XZ00 (57% identity). InterPro (IPR000286): Histone deacetylase superfamily Pfam (PF00850): Histone deacetylase domain.; Family membership
YP_933106.1	Conserved hypothetical protein. Homology to Rv2569c/MT2645/Mb2599c of M. bovis of 38%. Pfam: Transglutaminase-like superfamily. no signal peptide no TMHs; Specificity unclear
YP_933107.1	Conserved hypothetical protein,52% Identity to TrEMBL;Q9HUN7. Has PF04169;Domain of unknown function (DUF404);(IPR007297)This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF407 (IPR007302). Has PF04174;Domain of unknown function (DUF407);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF404 (IPR007297). Has PF04168;Bacterial domain of unknown function (DUF403);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF404 (IPR007297) and DUF407 (IPR007302).; Specificity unclear
YP_933108.1	Transglutaminase-like superfamily domain protein;67% identity (79% similarity) to TrEMBL;Q87VL0. TrEMBL;Q6N3E0(57% identity). Has SMART;SM00460,TGc;Transglutaminase/protease-like homologues: (IPR002931):Transglutaminases are enzymes that establish covalent links between proteins. A subset of transglutaminase homologues appear to catalyse the reverse reaction, the hydrolysis of peptide bonds. Proteins with this domain are both extracellular and intracellular, and it is likely that the eukaryotic intracellular proteins are involved in signalling events. NO signal peptide or TMH present.; High confidence in function and specificity
YP_933109.1	Hippurate hydrolase (EC 3.5.1.32) (Benzoylglycine amidohydrolase) (Hippuricase). TREMBL:Q7WFU4: 48% identity, 58% similarity InterPro:IPR002933; Peptidase_M20. IPR010168; Pept_M20D_amidh. Pfam: PF01546; Peptidase_M20; 1. TIGRFAMs TIGR01891; amidohydrolases No signal peptide present No transmembrane helices present mreB: cell shape determining protein M; High confidence in function and specificity
YP_933110.1	Similar to TREMBL:Q7WGZ1 (41% identity); TREMBL:Q7W9R7 (41% identity); TREMBL:Q8XXM2 (37% identity). Pfam (DUF214): Predicted permease. TMHMM reporting 10 transmembrane helices.; Specificity unclear
YP_933111.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
YP_933112.1	hypothetical protein having 55% similarity with Nitrosomonas europaea No Signal peptide present No TMH reported.
YP_933113.1	Conserved hypothetical ATP-dependent protease. Homology to gsu2433 of G. sulfurreducens of 40% (tremblnew|AAR35806). Tigrfam:lon_rel: ATP-dependent protease puta no signal peptide no TMHs; High confidence in function and specificity
YP_933114.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_933115.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_933116.1	Low molecular weight protein-tyrosine-phosphatase,; High confidence in function and specificity
YP_933117.1	Probable ribonuclease E (EC 3.1.4.-) (RNase E). Homology to rne of E. coli of 44% (sprot|RNE_ECOLI) This protein matures 5S rRNA from its precursors from all the rRNA genes. It is the major endoribonuclease participating in mRNA turnover. Interpro: Ribonuclease E and G (IPR004659); S1 RNA binding domain (IPR003029) Pfam: S1 RNA binding domain Tigrfam: RNase EG: ribonuclease,Rne/Rng family no signal peptide no TMHs; Family membership
YP_933118.1	Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil at positions 955 2504 and 2580 in 23S ribosomal RNA.; Family membership
YP_933119.1	TREMBL:Q7VSFO: Probable hydrolase, 55% identity,63% similarity Phosphoglycolate phosphatase (PGP). InterPro:PR006402; HAD-SF-IA-v3. IPR006439; HAD_SF_A_v1. IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Haloacid dehaloginase like hydrolase TIGRFAMs:TIGR01549; HAD-SF-IA-v1; TIGR01509; HAD-SF-IA-v3; serB: phosphoserine phosphatase SerB hstdl_phs_rel: histidinol phosphatase-; Function unclear
YP_933120.1	Conserved hypothetical ferredoxin subunits of nitrite reductase. Conserved Rieske domain is present. Similar to NirD from E.Coli. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit Non-secretory protein; Function unclear
YP_933121.1	Conserved hypothetical peptidase. Haomology to ne1024 of N. europaea of 59% (trembl|Q82VP2) InterPro: Peptidase family U7 (IPR002142) Tigrfam: SppA_dom: signal peptide peptidase SppA Pfam: Peptidase family U7 no signal peptide probable 1 TMH; High confidence in function and specificity
YP_933122.1	Conserved hypothetical protein. Homology to bpp3312 of B. parapertussis (trembl|Q7WD15). TIGR00096: conserved hypothetical protein Pfam: Tetrapyrrole (Corrin/Porphyrin) Methyltransferase no signal peptide no TMHs
YP_933123.1	Maf-like protein yceF. InterPro: Maf-like protein; Family membership
YP_933124.1	Conserved hypothetical protein. Homology to CV3419 of Chromobacterium violaceum of 42% (trembl:Q7NSK4). Has PF02620, Uncharacterized ACR,IPR003772;This entry describes proteins of unknown function. No signal peptide. No TMHs
YP_933125.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_933126.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_933127.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_933128.1	Probable malonyl CoA-acyl carrier protein transacylase. Homology to fabD of E. coli of 54% (sprot|FABD_ECOLI). Is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein. InterPro: Acyl transferase domain (IPR001227); Manyl CoA-acyl carrier protein transaylase (IPR004410) Pfam: Acyl transferase domain Tigrfam: fabD: malonyl CoA-acyl carrier protein no signal peptide no TMHs; High confidence in function and specificity
YP_933129.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_933130.1	carries the fatty acid chain in fatty acid biosynthesis
YP_933131.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_933132.1	Conserved hypothetical membrane protein. Homology to ebA5460 of Azoarcus sp. EbN1 of 32% (gnl|keqq|eba:ebA5460(KEGG)). No domains predicted. No signal peptide. 2 TMHs; Conserved hypothetical protein
YP_933133.1	catalyzes the formation of oxaloacetate from L-aspartate
YP_933134.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
YP_933135.1	Putative sigma-E factor, negative regulatory protein,; High confidence in function and specificity
YP_933136.1	Putative sigma factor regulatory protein,; High confidence in function and specificity
YP_933137.1	Putative sigma-E factor regulatory protein RseC,; High confidence in function and specificity
YP_933138.1	Probable serine protease MucD. Homology to mucD of P. aruginosa of 47% (trembl|Q57155) InterPro: Serine proteases trypsin family (IPR001254); PDZ domain (also known as DHR or GLGF) (IPR001478); Chymotrypsin serin protease family (S1) (IPR001314); HtrA/DegQ protease family (IPR001940) Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs ahpD_dom: alkylhydroperoxidase AhpD fam; High confidence in function and specificity
YP_933139.1	Conserved hypothetical thioredoxin. Homology to a putative thioredoxin of N. menigitidis (NMA0966) of 50%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. no signal peptide no TMHs; Function unclear
YP_933140.1	HTH-type transcriptional regulator,; Family membership
YP_933141.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide 3 TMHs
YP_933142.1	Putative exported protein, 39% identity (54% similarity)to TrEMBL;Q7VUI5 TrEMBL;Q7WNJ8. Has PF03401;Bordetella uptake gene (bug) product;(IPR005064)These probable extra-cytoplasmic solute receptors are strongly overrepresented in several beta-proteobacteria. SIgnal Peptide Present. No TMH reported present.; Specificity unclear
YP_933143.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_933144.1	Signal peptidase I (EC 3.4.21.89) (SPase I) (Leader peptidase I). SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by one or two N-terminal transmembrane domains, with the main part of the protein protuding in the periplasmic space. SPase I can cleave N-terminal leader sequences of nonlipoprotein that are exported by the SecYEG pathway or the twin arginine translocation (Tat) pathway. Pfam: Peptidase_S26 probable 2 TMH no signal peptide; High confidence in function and specificity
YP_933145.1	Conserved hypothetical secreted protein. Homology with NE2325 of N.europaea of 41% (tremble:Q82SJ5) No domains predicted. Signal peptide Present. No TMH reported.; Conserved hypothetical protein
YP_933146.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_933147.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_933148.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_933149.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
YP_933150.1	Holo-[acyl-carrier-protein] synthase, 50% Identity to TrEMBL;Q7NWB8, Q820I1. SProt;Q9KPB6(49%). Has PF01648,4'-phosphopantetheinyl transferase superfamily; IPR008278 4-PPT_transf; Members of this family transfers the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to the invariant serine of PP-binding. This post-translational modification renders holo-ACP capable of acyl group activation via thioesterification of the cysteamine thiol of 4'-PP. This superfamily consists of two subtypes: The ACPS type such as P24224 and the Sfp type such as P39135. The structure of the Sfp type is known which shows the active site accommodates a magnesium ion. The most highly conserved regions of the alignment are involved in binding the magnesium ion.
YP_933151.1	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
YP_933152.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_933153.1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (PGP synthase). It catalyses the conversion of CDP-diacylglycerol and glycerol-3-phosphate to CMP and 3-(3-phosphatidyl)-glycerol 1-phosphate in the commited step to the synthesis of acidic phospholipids. It is an integral membrane protein. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. Entry name :-SWISSPROT:PGSA_ECOLI Prim. accession # P06978 Identities = 50% InterPro IPR000462; CDP-OH_P_trans. IPR004570; PgsA. Pfam PF01066; CDP-OH_P_transf; 1. Number of predicted TMHs: 5 Prediction: Non-secretory protein Signal peptide probability: 0.109; Family membership
YP_933154.1	Probable Serine--pyruvate aminotransferase mitochondrial precursor (EC 2.6.1.51) (SPT) (Alanine--glyoxylate aminotransferase) (EC 2.6.1.44) (AGT). TREMBL:Q7P1E0:36% identity, 45% similarity This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase I / nucleotide pyrophosphatase (nppase). These enzymes catalyse the cleavage of phosphodiester and phosphosulphate bonds in NAD, deoxynucleotides and nucleotide sugars InterPro:IPR002591; Phosphodiest. Pfam:PF01663; Phosphodiest; bcpB: phosphonopyruvate decarboxylase-rel No transmembrane helices; Function unclear
YP_933155.1	Hypothetical protein. No homologs in the database. Has No domains, repeats, motifs or features.
YP_933156.1	Conserved hypothetical protein. Homology to RS03611 of R.solanacearum of 40% (trembl:Q8XXR7). Has PF06676(IPR009562):Protein of unknown function (DUF1178);This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. No signal peptide or TMH reported present.
YP_933157.1	Putative Autotransporter30% identity to TrEMBL;Q87UU2. Weak homology with hits in the DB. Signal Peptide present. No TMH reported present. Has PF03797;Autotransporter beta-domain;The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
YP_933158.1	Homology to cell division topological specificity factor minE.; Family membership
YP_933159.1	Septum site-determining protein minD (Cell division inhibitor minD).; High confidence in function and specificity
YP_933160.1	Probable septum site-determining protein minC.; Family membership
YP_933161.1	Putative 33 kDa chaperonin. Homology to hslO of E. coli of 32% (sprot|HSLO_ECOLI) Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity). InterPro: Hsp33 protein (IPR000397) Pfam: Hsp33 protein no signal peptide no TMHs; Family membership
YP_933162.1	45% Arsen_reductase.IPR006504; Cons_hypoth_ArsC. Pfam:PF03960; ArsC; 1. ArsC:arsenate reductase, catalyzes the reduction of arsenate to arsenite. Probably involved in arsenic resistance.; High confidence in function and specificity
YP_933163.1	Transcription accessory protein (S1-domain containing RNA binding protein),; High confidence in function and specificity
YP_933164.1	Possible aldose 1-epimerase.Aldose 1-epimerase (mutarotase), responsible for the anomeric interconversion of D-glucose and other aldoses between their alpha- and beta-forms. InterPro:IPR008183; Ald1_epimerase. Pfam:PF01263; Aldose_epim; 1.
YP_933165.1	Conserved hypothetical protein. Homology to cv3676 of C. violaceum of 47% (trembl|Q7NRV4). InterPro: DUF184 (IPR003781). Pfam: CoA binding domain; Acetyltransferase (GNAT) family. No signal peptide. No TMHs
YP_933166.1	Putative two-component system sensor protein, 3 Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices.; Function unclear
YP_933167.1	TREMBL:Q8EI75-35% identity, 54% similarity TREMBLnew:AAS81097 InterPro: SAM (and some other nucleotide) binding motif tehB: tellurite resistance protein TehB. Toxin production and resistance responsible for potassium tellurite resistance when present in high copy number, probably by increasing the reduction rate of tellurite to metallic tellurium within the bacterium. otherwise, phenotypically silent.cytoplasmic (potential). was originally (ref.1) thought to be plasmid encoded.InterPro IPR000051; SAM_bind. IPR004537; TehB. Pfam PF03848; TehB; 1. TIGRFAMs:TIGR00477; tehB; 1. INDUCES AGGLUTINATION OF NEURAMINIDASE-TREATED ERYTHROCYTES.; Conserved hypothetical protein
YP_933168.1	catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
YP_933169.1	catalyzes the formation of selenophosphate from selenide and ATP
YP_933170.1	Probable acyl-CoA thioesterase. Homology to tesA of E. coli of 42% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase with GDSL-like motif signal peptide no TMH; Family membership
YP_933171.1	Similar to TREMBL:Q82UM8 (55% identity); TREMBL:Q8XYP0 (59% identity); TREMBL:Q7W685 (59% identity). Pfam (PF00005): ABC transporter.; Specificity unclear
YP_933172.1	Phosphoserine phosphatase, SerB, catalyzes the final step in serine biosynthesis in E. coli. It hydrolyses the phosphate group from phosphoserine to yield serine. Similar to trembl|Q82X56 (54%) and to sprot|SERB_ECOLI (37%). TIGRFAM: phosphoserine phosphatase SerB Pfam (PF00702): haloacid dehalogenase-like hydrolase; Specificity unclear
YP_933173.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive
YP_933174.1	Conserved hypothetical secreted protein. Homology to PA2869 of P.aeruginosa of 32% (trembl:Q9HZX7). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_933175.1	GGDEF/EAL/PAS/PAC-domain containing protein
YP_933176.1	Magnesium and cobalt transport protein CorA. Plays a role in the transport of Magnesium and Cobalt ions. Homolog to E.coli and S.typhimurium, magnesium and cobalt proteins. InterPro:IPR002523; Mg2+_transptCorA. Pfam: PF01544; CorA; 1. THM:2; Function unclear
YP_933177.1	Transcription-repair coupling factor (TRCF). NECESSARY FOR STRAND-SPECIFIC REPAIR. A LESION IN THE TEMPLATE STRAND BLOCKS THE RNA POLYMERASE COMPLEX (RNAP). THE RNAP-DNA-RNA COMPLEX IS SPECIFICALLY RECOGNIZED BY TRCF WHICH RELEASES RNAP AND THE TRUNCATED TRANSCRIPT; THE TCRF MAY REPLACE RNAP AT THE LESION SITE AND THEN RECRUIT THE UVRA/B/C REPAIR SYSTEM. mfd: transcription-repair coupling fa; High confidence in function and specificity
YP_933178.1	Conserved hypothetical protein. Homology to CV1155 of Chromobacterium violaceum of 35% (gnl|keqq|cvi:CV1155(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933179.1	Probable DNA fragmentation factor 40 kDa subunit (EC 3.-.-.-) (DFF-40) (Caspase-activated deoxyribonuclease) (Caspase-activated DNase) (CAD). Members of PRT family are catalytic and regulatory proteins involved in nucleotide synthesis and salvage. The name PRT comes from phosphoribosyltransferase enzymes,which carry out phosphoryl transfer reactions on PRPP, an activated form of ribose-5-phosphate. This family includes a range of diverse phosphoribosyl transferase enzymes TREMBL:Q7WXA5: 29% identity, 47% similarity InterPro:IPR000836; PRtransferase. Pfam: PF00156; Pribosyltran; 1. acid_CoA_mut_C: methylmalonyl-CoA muta Non-secretory protein with low probability of signal peptide (0.001) No transmembrane helices; Function unclear
YP_933180.1	conserved hypothetical pyruvat formate-lyase activiating enzyme. Homology to pflA of M. tuberculosis of 64% (trembl|P95188). no domains predicted no signal peptide no TMHs; Family membership
YP_933181.1	Conserved hypothetical protein. Homology to Daro03002649 of Dechloromonas aromatica of 39% (gi|41723559|ref|ZP_00150469.1|(NBCI ENTREZ)). No domains predicted. No TMH. No signal peptide.
YP_933182.1	Putative cyclic nucleotide-binding protein,; Specificity unclear
YP_933183.1	Hypothetical protein, 38% identity to SwissProt;O26945 Has PF01871;AMMECR1;(IPR002733, DUF 51)This family consists of several AMMECR1 as well as several uncharacterised proteins. The contiguous gene deletion syndrome AMME is characterised by Alport syndrome, midface hypoplasia, mental retardation and elliptocytosis and is caused by a deletion in Xq22.3,comprising several genes including COL4A5, FACL4 and AMMECR1. This family contains sequences from several eukaryotic species as well as archaebacteria and it has been suggested that the AMMECR1 protein may have a basic cellular function, potentially in either the transcription, replication, repair or translation machinery.; Specificity unclear
YP_933184.1	Hypothetical UPF0103 protein ST2062. This gene is conserved in several species ranging from Caenorhabditis elegans and yeast to plants and micro-organisms although no function has yet been ascribed to the other proteins in this family. TREMBL:Q843N3: 38% identity,52% similarity InterPro:IPR002733; DUF51. IPR002737; DUF52. Pfam: PF01871; AMMECR1; 1. PF01875; UPF0103 Signal peptide present No transmembrane helices holB: DNA polymerase III delta prime sub; Function unclear
YP_933185.1	Conserved hypothetical membrane protein. TrEMBL; Q82Y76(48% identity). TMHMM2 reporting 14 TMH's present. Signal Peptide not present. Has PF02308;MgtC family;(IPR003416 MgtCSapB_transpt)The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known, but it is thought that MgtC may act as an accessory protein for MgtB, thus mediating magnesium influx into the cytosol. Also included in this family are the Bacillus subtilis SapB protein and several hypothetical proteins. Has PF04093 rod shape-determining protein MreD;IPR007227; MreD (murein formation D) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped.; Conserved hypothetical protein
YP_933186.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_933187.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
YP_933188.1	Conserved hypothetical protein. Homology to pc0921 of Parachlamydia_UWE25 of 34% (pcu:pc0921(KEGG)). No signal peptide reported to be present. No TMH reported to be present. No domains predicted.
YP_933189.1	Conserved hypothetical protein. Homology to NE0619 of Nitrosomonas europaea of 44% (trembl:Q82WP5). Has PF06167, IPR010384; Protein of unknown function (DUF980);Family of uncharacterised bacterial sequences. No signal peptide. No TMHs.
YP_933190.1	Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 42% (tremble:Q7NV15) InterPro: Integral membrane protein DUF6 Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transport Pfam: Integral membrane protein DUF6 no signal peptide probable 10 TMHS; Conserved hypothetical protein
YP_933191.1	Similar to membrane carboxypeptidases.; Family membership
YP_933192.1	GTP pyrophosphokinase,; High confidence in function and specificity
YP_933193.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_933194.1	45% Ppx_GppA. Pfam:PF02541; Ppx-GppA; 1.; High confidence in function and specificity
YP_933195.1	Conserved hypothetical membrane protein. Similar to TREMBL:Q8Y2M2 (43% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
YP_933196.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7W0L5 (51% identity); TREMBL:Q9A5X8 (46% identity). InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership
YP_933197.1	Conserved hypothetical secreted protein. Homology to bb0165 of B. bronchiseptica of 31% (TREMBL:Q7WR07). Pfam: mce related protein This family of proteins contains the mce (mycobacterial cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within, the macrophage. This family contains proteins of unknown function from other bacteria. Signal peptide. no TMHs; Conserved hypothetical protein
YP_933198.1	Conserved hypothetical protein. Homology to ebA6519 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA6519(KEGG)). no domains predicted. signal peptide present. no TMHs.
YP_933199.1	activates fatty acids by binding to coenzyme A
YP_933200.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_933201.1	Putative deoxyribonuclease yjjV (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family.; High confidence in function and specificity
YP_933202.1	Tetracycline repressor protein class G. Similar to SWISSPROT: sprot|TER7_VIBAN (21% Vibrio anguillarum (Listonella anguillarum), tetracycline repressor protein class G). TETR IS THE REPRESSOR OF THE TETRACYCLINE RESISTANCE ELEMENT; ITS AMINO-TERMINAL REGION FORMS A HELIX-TURN-HELIX STRUCTURE AND BINDS DNA. BINDING OF TETRACYCLINE TO TETR REDUCES THE REPRESSOR AFFINITY FOR THE TETRACYCLINE RESISTANCE GENE (TETA) PROMOTER OPERATOR SITES. InterPro: IPR001647 HTH_TetR. Pfam: PF00440 Bacterial regulatory proteins, tetR family. HTH reporting nucleic acid binding motif.; Family membership
YP_933203.1	Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity
YP_933204.1	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 65% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity
YP_933205.1	Conserved hypothetical membrane protein. Homology to CV1589 of Chromobacterium violaceum of 36% (trembl|Q7NXN7(SRS)). Has PF01891;CbiM;(IPR002751)This integral membrane protein is involved in cobalamin synthesis. No signal peptide. 5 TMHs; Conserved hypothetical protein
YP_933206.1	Acyl-CoA dehydrogenase short/branched chain specific mitochondrial precursor (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase). Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA isobutyryl-CoA and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent. Entry name TREMBL:Q8Y0W8 Identities = 358/596 (60%) InterPro IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1.; Family membership
YP_933207.1	Cell binding factor 2 precursor (Major antigen peb4A). Homology to cbf2 of C. jejuni of 34% (sprot|CBF2_CAMJE). Belongs to the ppic/parvulin rotamase family InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain signal peptide no TMH; Family membership
YP_933208.1	Region start changed from 1873054 to 1872976 (-78 bases)
YP_933209.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
YP_933210.1	Involved in cell division; probably involved in intracellular septation
YP_933211.1	Conserved hypothetical globin-like protein. Homology to bd2638 of B. bacteriovorus of 57% (tremblnew|CAE80431). Globins are heme-containing proteins involved in binding and/or transporting oxygen. This family of heme binding proteins are found mainly in bacteria. However they can also be found in some protozoa and plants as well. InterPro: Protozoan/cyanobacterial globins (IPR001486) Pfam: Bacterial-like globin. no signal peptide. no TMHs; Family membership
YP_933212.1	Probable osmolarity sensor protein EnvZ,; Specificity unclear
YP_933213.1	part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation
YP_933214.1	Hypothetical secreted protein. No homologs in the database. Signal Peptide present. No TMHs. No domains predicted
YP_933215.1	Conserved hypothetical glycoprotease. Homology to yeaZ of N. europae of 41% (trembl|Q82US9). InterPro: Glycoprotease (M22) metallo-protease family (IPR000905). Tigrfam: gcp: metalloendopeptidase putative glycoprotease family. Pfam: Glyocprotease family. no signal peptide. no TMHs.; Family membership
YP_933216.1	Conserved hypothetical ribosomal-protein-alanine acetyltransferase. Homology to ebA6491 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA6491(KEGG)). Pfam: Acetyltransferase (GNAT) family. Tigrfam: ribosomal-protein-alanine acetyltransferase. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_933217.1	Putative DNA polymerase-related protein,bacteriophage-type. TIGRFAM: rad23: UV excision repair protein Rad23; Specificity unclear
YP_933218.1	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Homolog to the hypothetical protein ygeD, a putative resistence protein from Y. pestis(by similarity). 2A0121: H+ Antiporter protein; High confidence in function and specificity
YP_933219.1	Trans-acting transcriptional regulator of RuBisCO genes expression Putative HTH-type transcriptional regulator Contains 1 HTH lysR-type DNA-binding domain,belonds to the LysR family InterPro: Bacterial regulatory protein LysR family ModE_repress: ModE molybdate transport 32% HTH_LysR. IPR005119; LysR_subst. IPR009058; Wing_hlx_DNA_bnd. PF00126; HTH_1; 1. PF03466; LysR_substrate; 1; High confidence in function and specificity
YP_933220.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_933221.1	Hypothetical protein . Extremely weak homology with any hits in the database. No Features,signal Peptide,motifs are known domains present.
YP_933222.1	Hypothetical protein, has very weak homology with hits in the Database(TrEMBL;Q63I29) Coils2 program reporting presence of coiled-coiled.
YP_933223.1	Conserved hypothetical protein. Homology to ebA7025 of Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA7025(KEGG)). Pfam: Glycos_transf_2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. No signal peptide. No TMHs
YP_933224.1	Family membership
YP_933225.1	Similar to waaQ.; Family membership
YP_933226.1	Hypothetical protein, weak homology with hits. TrEMBL;Q9KPT2(45% identity) No domains, repeats, motifs or features present.
YP_933227.1	Conserved hypothetical protein. Homology to blr5713 of B.japonicum of 45% (tremble:Q89IC6). No domains predicted. No TMHs. SignalP 3.0 predicts no signal peptide.
YP_933228.1	Conserved hypothetical protein. Homology to SMA1058 of S.meliloti of 48% (trembl:Q92ZB7). No domains predicted. No signal peptide. No TMHs
YP_933229.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_933230.1	O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety.Probable glucanohydrolase Pep1B. Could convert glycogen into units that may be subsequently converted into trehalose.Belongs to family 13 of glycosyl hydrolases. Glge subfamily. 47% Alpha_amyl_cat. Pfam:PF00128; alpha-amylase; 1.; High confidence in function and specificity
YP_933231.1	Trehalose synthase(Maltose alpha-D-glucosyltransferase).Catalyzes the conversion of maltose into alpha,alpha- trehalose by transglucosylation. 54% Alp_amyl_cat_sub.IPR006047; Alpha_amyl_cat.InterPro: Glycoside hydrolase family 13. Pfam:PF00128; alpha-amylase; 1.; High confidence in function and specificity
YP_933232.1	Conserved hypothetical secreted protein. Homology to BPP3320 of B.bronchiseptica of 31% (tremble:Q7W5H1). No domains predicted. Signap P reporting signal peptide. No TMH reported.; Conserved hypothetical protein
YP_933233.1	Conserved hypothetical protein. Homology to mm2747 of M. mazei of 39% (trembl|Q8PTG8(SRS). no domains predicted. no TMHs. no signal peptide.
YP_933234.1	Conserved hypothetical protein. Homology to ebA6994 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA6994(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933235.1	Hypothetical membrane protein. No homology to the data bank. No domain prediction. No signal peptide. 1 TMH
YP_933236.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Family membership
YP_933237.1	Hypothetical protein with unknown function. Domain predicted by Pfam, PF01381 Helix-turn-helix.
YP_933238.1	Entry name TREMBL:Q89PM4 Identities = 257/546 (47%) Prediction: Non-secretory protein Signal peptide probability: 0.018 Number of predicted TMHs: 0 pts-lac: PTS system lactose/cellobios
YP_933239.1	Conserved hypothetical protein. Homology to rO1139 of S. meliloti of 48% (trembl|Q92QZ6). No domains predicted. No signal peptide. No TMHs
YP_933240.1	Hypothetical protein. No good homology with any Hits in the database.
YP_933241.1	Conserved hypothetical membrane protein. Homology to ebA6987 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA6987(KEGG)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein
YP_933242.1	Hypothetical protein has weak homology to Transglycosylase of penicillin-binding protein 1c(pbpC).TrEMBL:Q8ZN47(56%). ***Contains PRC-barrel domain(pfam05239). The PRC-barrel is an all beta barrel domain found in photosystem reaction centre subunit H of the purple bacteria and RNA metabolism proteins of the RimM group. PRC-barrels are approximately 80 residues long, and found widely represented in bacteria, archaea and plants. This domain is also present at the carboxyl terminus of the pan-bacterial protein RimM, which is involved in ribosomal maturation and processing of 16S rRNA. A family of small proteins conserved in all known euryarchaea are composed entirely of a single stand-alone copy of the domain. No Signal Peptide reported. No TMH's reported.
YP_933243.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:O32291 (45% identity); SWISSPROT:P54554 (28% identity). Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933244.1	conserved hypothetical protein, 49% identity to TrEMBL;Q7W766. Has SMART;SM00559;Ku78;Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen;(IPR006164);This is a single stranded DNA- and ATP-depedent helicase that has a role in chromosome translocation. This is a domain of unknown function C-terminal to its von Willebrand factor A domain, that also occurs in bacterial hypothetical proteins.
YP_933245.1	catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA
YP_933246.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal peptide present. No TMHs.
YP_933247.1	Conserved hypothetical protein. Homology to ebA6983 of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebA6983(KEGG)). Pfam: N-formylglutamate amidohydrolase. Formylglutamate amidohydrolase (FGase) catalyses the terminal reaction in the five-step pathway for histidine utilisation in Pseudomonas putida. By this action, N-formyl-L-glutamate (FG) is hydrolysed to produce L-glutamate plus formate. no signal peptide. no TMHs
YP_933248.1	Hypothetical protein,32% identity (49% similarity) to SwissProt;O27977 Has PF04107;Glutamate-cysteine ligase family 2(GCS2);(IPR006336)Also known as gamma-glutamylcysteine synthetase and gamma-ECS. This enzyme catalyses the first and rate limiting step in de novo glutathione biosynthesis. Members of this family are found in archaea, bacteria and plants. May and Leaver [1] discuss the possible evolutionary origins of glutamate-cysteine ligase enzymes in different organisms and suggest that it evolved independently in different eukaryotes,from an ancestral bacterial enzyme. They also state that Arabidopsis thaliana gamma-glutamylcysteine synthetase is structurally unrelated to mammalian, yeast and Escherichia coli homologues. In plants, there are separate cytosolic and chloroplast forms of the enzyme.
YP_933249.1	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) rimK_fam: S6 modification enzyme RimK; Specificity unclear
YP_933250.1	Conserved hypothetical protein. Homology to TdenA01000334 of Thiobacillus denitrificans of 67% (gi|52008038|ref|ZP_00335415.1|(NBCI ENTREZ)). No domains present. No signal peptide. No TMHs.
YP_933251.1	Hypothetical secreted protein. No homology to the data bank. No TMHs Signal Peptide present. Has PS50914; BON;The BON (bacterial OsmY and nodulation) domain is found in the bacterial osmotic-shock-resistance protein OsmY, a family of haemolysins, a group of nodulation specificity proteins and secretory channels, and several hypothetical proteins. It is typically about 60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions.
YP_933252.1	Hypothetical protein yhcV. TREMBL:Q92V69:54%identity, 76% similarity. TREMBL:Q81UY6 Pfam:CBS domain, Anticodon binding domain. TIGRFAM: KpsF/GutQ family proteins. No signal peptide or transmembrane helix reported. CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. Pairs of CBS domains dimerise to form a stable globular domain. Two CBS domains are found in inosine-monophosphate dehydrogenase from all species, however the CBS domains are not needed for activity. CBS domains are found attached to a wide range of other protein domains suggesting that CBS domains may play a regulatory role. The region containing the CBS domains in Cystathionine-beta synthase is involved in regulation by S-AdoMet.. A number of disease states are associated with CBS-containing proteins including homocystinuria, Becker's and Thomsen disease. InterPro: CBS domain urease_gam: urease gamma subunit; Function unclear
YP_933253.1	Conserved hypothetical membrane protein. Homology to r02018 of S. meliloti of 72% (trembl|Q92K67(SRS). no damains predicted .signal peptide. 1 TMH; Conserved hypothetical protein
YP_933254.1	Hypothetical membrane protein. No homology of the entire protein to the data bank. Has DUF1328(Protein of Unknown family) domain. PF07043;IPR009760; This family consists of several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown. no signal peptide. 3 TMHs
YP_933255.1	Conserved hypothetical secreted protein. Homology to ebA6968 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA6968(KEGG)). Pfam: Putative phospholipid-binding domain This domain is found in a family of osmotic shock protection proteins (e.g. P27291). It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_933256.1	Conserved hypothetical secreted protein: Homology to ne0129 of N. europaea of 43% (trembl|Q82XW6). Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. signal peptide. no TMHs; Conserved hypothetical protein
YP_933257.1	Function:- Cardiolipin synthetase (CL synthase),cls. Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Entry name :-SWISSPROT:CLS_ECOLI Prim. accession # P31071 InterPro:IPR001736; PLD. Identities = 114/379 (30%) Pfam:PF00614; PLDc; 2. TMhelix=1 Signal peptide probability: 1.0; Family membership
YP_933258.1	Conserved hypothetical membrane protein. Homology Avin02003871 of Azotobacter vinelandii of 47% (gi|53610588|ref|ZP_00089122.2|(NBCI ENTREZ)). Has PF03653, Uncharacterised protein family (UPF0093). Interpro: IPR005265; Cons_hypoth701; It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein
YP_933259.1	Conserved hypothetical membrane protein. Homology ebA159 of Azoarcus sp. EbN1 of 52% (gnl|keqq|eba:ebA159(KEGG)). No domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein
YP_933260.1	Probable quniol oxidase, subunit II. Homology to qoxB of Rhodobacter sphaeroides of 41% (gi|4416093|gb|AAD20226.1|(NBCI ENTREZ)). InterPro: Cytochrome c oxidase subunit II (IPR002429); Cu(A) centre of cytochrome c oxidase, subunit II and nitrous oxide reductase (IPR001505). Pfam: Cytochrome c oxidase subunit II, periplasmic. no signal peptide. 2 TMHs; Family membership
YP_933261.1	Probable quinol oxidase, subunit I. Homology to qoxA of R. sphaeroides of 52% (trembl|Q9Z605). InterPro: Cytochrome c oxidase subunit III (IPR000298); Cytochrome coxidase, subunit I (IPR000883) Pfam: Cytochrom C and quinol oxidase poly polypeptide signal peptide 17 TMHs; Family membership
YP_933262.1	Hypothetical membrane protein. no homology to the data bank. no domains predicted. no signal peptide. 3 TMHs
YP_933263.1	Conserved hypothetical membrane protein. Homology to Avin02003353 of Azotobacter vinelandii of 48% (gi|53610930|ref|ZP_00342175.1|(NBCI ENTREZ)). No domains predicted. signal peptide. 7 TMHs; Conserved hypothetical protein
YP_933264.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8KUH7 (41% identity); SWISSPROT:P14802 (30% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933265.1	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748).; Specificity unclear
YP_933266.1	Conserved hypothetical membrane protein. Homology to XCC0079 of Xanthomonas campestris (trembl|Q8PEA2(SRS)). InterPro:IPR002549; UPF0118. Pfam PF01594; domain of DUF20 present. no signal peptide. 8 TMHs; Conserved hypothetical protein
YP_933267.1	Probable serine protease MucD. Homology to mucD of P. aeruginosa of 40% (trembl|Q57155). InterPro: Serine proteases trypsin family (IPR001254); Chymotrypsin serine protease family (S1) (IPR001314); HtrA/DegQ protease family (IPR001940); PDZ domain (also known as DHR or GLGF) (IPR001478) Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity
YP_933268.1	Conserved hypothetical secreted protein. Homology to bb3588 of B. bronchiseptica of 41% (trembl|Q7WGK1). Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. signal peptide. TMH in signal peptide; Conserved hypothetical protein
YP_933269.1	Conserved hypothetical membrane protein. Homology to Atu4467 of Agrobacterium tumefaciens of 58% (trembl|Q8U7I2). Has PF07043, Protein of unknown function (DUF1328);IPR009760;This family consists of several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown. signal peptide. 1 TMHs; Conserved hypothetical protein
YP_933270.1	Probable NADH dehydrogenase. Homology to ndh of P. fluorescens of 48% (trembl|Q9KGX0). TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. Interpro: FAD-dependent pyridine nucleotide-dislphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disluphide oxidoreductase no signal peptide no TMHs; Family membership
YP_933271.1	Conserved hypothetical protein. Homology to an orf of Polyangium cellulosum of 69% (tremble:Q9L8D1). Has PF07100;(IPR009794)Protein of unknown function (DUF1362);This family consists of several hypothetical bacterial proteins of around 125 resides in length. The function of this family is unknown. No signal peptide or TMH reported present.
YP_933272.1	Hypothetical membrane protein. no homology of the entire protein to the data bank. no domains predicted no signal peptide 1 TMH
YP_933273.1	Conserved hypothetical protein. Weak homology with hits in the database. Coils2 program predicts presence of coiled coil.
YP_933274.1	Conserved hypothetical DnaK suppressor protein. Homology to BPSS2280 of Burkholderia pseudomallei of 34% (gnl|keqq|bps:BPSS2280(KEGG). Has PF01258, Prokaryotic dksA/traR C4-type zinc finger; IPR000962 Znf_DskA/TraR; The dksA gene product suppresses the temperature-sensitive growth and filamentation of a dnaK deletion mutant of Escherichia coli. Gene knockout and deletion experiments have shown the gene to be non-essential, mutations causing a mild sensitivity to UV light, but not affecting DNA recombination. The protein contains a C-terminal region thought to fold into a 4-cysteine zinc finger. Other proteins found to contain a similar domain include the traR gene product, present on the conjugative plasmid F,and several hypothetical proteins from bacteria and bacteriophages. No TMHs. No signal peptide.; Conserved hypothetical protein
YP_933275.1	Probable cyanide insensitive terminal oxidase,subunit I Homology to cioA of P. aeruginose of 44% (TREMBL:O07440) InterPro: Cytochrome bd ubiquinol oxidase subunit I (IPR002585) Pfam: Bacterial cytochrome ubiquinol oxidase no signal peptide no TMHs; High confidence in function and specificity
YP_933276.1	Probable cyanide insensitive terminal oxidase,subunit II. Homology to cioB of P. aeruginosa of 40% (trembl|O07441). Tigrfam: cydB: cytochrome d ubiquinol oxidase, subunit II Pfam: cytochrome oxidase, subunit II no signal peptide 8 TMHs; High confidence in function and specificity
YP_933277.1	Conserved hypothetical protein. Homology to an orf of P. putida of 58% (trembl|O68643). no TMHs. no signal peptide. No domains predicted.
YP_933278.1	Conserved hypothetical protein. Homology to Avin02003958 of Azotobacter vinelandii of 38% (gi|53610498|ref|ZP_00089565.2|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_933279.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH
YP_933280.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_933281.1	Hypothetical LuxR-family transcriptional regulator. Similarity to other known proteins (dctR or narP or esaR) only in the domain part. Pfam: PF00196 Bacterial regulatory proteins, luxR family. HTH reporting nucleic acid binding motif. The 'helix-turn-helix' DNA-binding motif of this protein is located in the C-terminal section of the sequence.; Conserved hypothetical protein
YP_933282.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 3 TMHs
YP_933283.1	This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). InterPro (IPR002502): N-acetylmuramoyl-L-alanine amidase (family 2). Pfam (PF01510): N-acetylmuramoyl-L-alanine amidase.; Family membership
YP_933284.1	Hypothetical protein. no homology of the entire protein to the data bank InterPro: Putative peptidoglycan binding domain 1 (IPR002477) Pfam: Putative peptidoglycan binding domain 1 no signal peptide no TMHs
YP_933285.1	Conserved hypothetical protein. Homology to map2952a of M. paratuberculosis of 51% (AAS05269). Pfam: CahB; Rho terminator factor, N-terminal. domain no signal peptide. no TMHs
YP_933286.1	Conserved hypothetical protein. Homology to mlr2853 of M. loti of 31% (trembl|Q98HI7). Tigrfam: xth: exodeoxyribonuclease III (xth). All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Pfam: AP endonuclease family I. no signal peptide. no TMHs
YP_933287.1	Conserved hypothetical membrane protein. Homology to ebA6946 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA6946(KEGG)). Pfam: Pospholipase D, active site motife; DedA family. no signal peptide. 6 TMHs; Conserved hypothetical protein
YP_933288.1	Bacterioferritin (BFR) (Cytochrome B-1) (Cytochrome B-557). In E. coli is an iron-storage protein consisting of 24 identical subunits that pack together to form a highly symmetrical, nearly spherical shell surrounding a central cavity of about 8 nm diameter.X-ray crystallographic studies have revealed a close structural similarity between BFR and the ferritins, a family of iron-storage proteins found in both eukaryota and prokaryota. Key role in iron homeostasis.InterPro: Bacterioferritin. Non-secretory protein bfr: bacterioferritin; High confidence in function and specificity
YP_933289.1	InterPro: Glycosyl transferases group 1; Family membership
YP_933290.1	Conserved hypothetical phosphoesterase family protein. Homology to ebA6940 of Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebA6940(KEGG)). InterPro IPR008934; AcPase_VanPerase. IPR000326; PA_PTPase. Pfam PF01569; PAP2; Number of predicted TMHs: 3#. Prediction: Non-secretory protein Signal peptide probability: 0.000; Conserved hypothetical protein
YP_933291.1	TIGR00093: conserved hypothetical protein; Function unclear
YP_933292.1	InterPro: Glycosyl transferases group 1; Family membership
YP_933293.1	Conserved hypothetical protein. Homology to bp0770 of B. pertussis of 37% (TrEMBL:Q7VZW1). no domains reported. no signal peptide. no TMHs
YP_933294.1	RNA polymerase sigma-54 factor. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Similar to SWISSPROT: sprot|RP54_ALCEU (46% Alcaligenes eutrophus (Ralstonia eutropha), RpoN or NtrA) / sprot|RP54_ECOLI (41% Escherichia coli, RpoN or NtrA) Pfam:PF00309 Sigma54_AID. PF04963 Sigma54_CBD. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_933295.1	Conserved hypothetical secreted protein. Homology to ebA6930 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_933296.1	Conserved hypothetical membrane protein. Homology to xcc0923 of X. campestris of 46% (trembl|Q8PC30). InterPro: Uncharacterized protein family UPF0003 (IPR006685). Pfam: Mechanosensitive ion chanell. Mechanosensitive (MS) channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation. no signal peptide. 5 TMHs; Conserved hypothetical protein
YP_933297.1	Conserved hypothetical protein.Weak Homology with Hits in the Database. Has IPR000967 Znf_NFX1;(SMART;SM00438)This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C, where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosophila shuttle craft protein, which plays an essential role during the late stages of embryonic neurogenesis; and a yeast hypothetical protein YNL023C. No signal peptide or TMH reported present.
YP_933298.1	Glycogen operon protein GlgX homolog.Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen. 46% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.F02922; isoamylase_N; 1.; High confidence in function and specificity
YP_933299.1	DNA topoisomerase I (EC 5.99.1.2). The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. cbiB: cobalamin biosynthesis protein.; Specificity unclear
YP_933300.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_933301.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_933302.1	Malto-oligosyltrehalose trehalohydrolase(MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase).Involved in the trehalose biosynthesis,hydrolysing alpha-(1->4)-d-glucosidic linkage in 4-alpha-d-{(1->4)-alpha-d-glucanosyl}(n) trehalose to yield trehalose and alpha-(1->4)-d-glucan. 42% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.PF02922; isoamylase_N; 1.; Specificity unclear
YP_933303.1	amylomaltase; acts to release glucose from maltodextrins
YP_933304.1	Glucokinase (EC 2.7.1.2) (Glucose kinase). Catalytic activity: ATP + d-glucose = ADP+ d-glucose 6-phosphate. 34% Glucokinase. Pfam:PF02685; Glucokinase; 1. TIGRFAMs:TIGR00749; glk; 1.; High confidence in function and specificity
YP_933305.1	Glycogen synthase (Starch [bacterial glycogen] synthase) GlgA. Synthesizes alpha-14-glucan chains using ADP-glucose. 46% Glyco_trans_1. Pfam:PF00534; Glycos_transf_1; 1.; High confidence in function and specificity
YP_933306.1	67% Epimerase_Dh. Pfam: PF01370; Epimerase; 1. No signal peptide.; Family membership
YP_933307.1	Conserved hypothetical glycosyltransferase. Homology to ebA6914 of Azoarcus sp. EbN1 of 72% (gnl|keqq|eba:ebA6914(KEGG)). Pfam: Glycos_transf_1. Interpro: Glycosyl transferase, group 1. Proteins containign this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis,lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_933308.1	Hypothetical 55.3 kDa protein in thcA 5region (ORF1).; High confidence in function and specificity
YP_933309.1	Hypothetical conserved hypothetical cabamoyltransferase. Homology to sco6480 of S. coelicolor of 49% (trembl|Q8CJN9). Pfam: Carbamyltransferase. no signal peptide. no TMHS; Conserved hypothetical protein
YP_933310.1	ADP-heptose--LPS heptosyltransferase II (EC 2.-.-.-). pdxJ: pyridoxal phosphate biosynthetic; High confidence in function and specificity
YP_933311.1	Hypothetical protein yaeD.; High confidence in function and specificity
YP_933312.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8YLL2 (35% identity); TREMBL:Q9HWN3 (37% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933313.1	Hypothetical protein Rv0486/MT0504/Mb0496. InterPro: Glycosyl transferases group 1; Specificity unclear
YP_933314.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH
YP_933315.1	Conserved hypothetical membrane protein. Homology to BPP2658 of B. parapertussis of 48% (trembl|Q7W772(SRS)). 3 TMHs. no signal protein. Has PF04239;Protein of unknown function (DUF421);IPR007353 DUF421; Conserved hypothetical protein
YP_933316.1	Probable transcriptional regulatory protein,; Specificity unclear
YP_933317.1	Hypothetical protein. Weak homology with hits.
YP_933318.1	Conserved hypothetical protein. Homology to ebD123 of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebD123(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933319.1	Hypothetical membrane protein. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. 2 TMHs
YP_933320.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted No signal peptide 2 TMHs
YP_933321.1	Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembrane helices.; Conserved hypothetical protein
YP_933322.1	Putative ribonuclease RNASE BN (RBN)Protein, 31% identity (44% similarity) to TrEMBL; Q8XPH6. Has PF03631; Ribonuclease BN-like family;IPR004664, RNase_BN;This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; Family membership
YP_933323.1	Hypothetical protein. Homology to dr0392 of D. radiodurans of 25% (trembl|Q9RXC3) Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. no signal peptide no TMHs; High confidence in function and specificity
YP_933324.1	Conserved hypothetical protein. Homology to BB2852 of B.bronchiseptica of 53% (tremble:Q7WIJ9). Has pfam05239, PRC, PRC-barrel domain. The PRC-barrel is an all beta barrel domain found in photosystem reaction centre subunit H of the purple bacteria and RNA metabolism proteins of the RimM group. PRC-barrels are approximately 80 residues long, and found widely represented in bacteria, archaea and plants. This domain is also present at the carboxyl terminus of the pan-bacterial protein RimM, which is involved in ribosomal maturation and processing of 16S rRNA. A family of small proteins conserved in all known euryarchaea are composed entirely of a single stand-alone copy of the domain. NO signal peptide reported to be present. No TMH reported to be present.
YP_933325.1	Conserved hypothetical membrane protein. Homology to ebA6882 of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebA6882(KEGG)). Domian structure: 373 aa -599 aa AAA ATPase; 638 aa - 726 aa HATPase_c; 750 aa - 877 aa Rec InterPro: ABC transporter (IPR003439); AAA ATPase superfamily (IPR003593); ABC transporter transmembrane region (IPR001140); ATP/GTP-binding site motif A ((P-loop) (IPR001687); (Response regulator reciver (IPR001789); Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase (IPR003594) Pfam: ABC-transporter ABC transmembrane region; Response regulator reciver domain. no signal peptide. probable 5 TMHs; Conserved hypothetical protein
YP_933326.1	Conserved hypothetical protein. Signal peptide present.
YP_933327.1	Putative Mg(2+) transporter ATPase [attV], 58% identity (77% similarity) to TrEMBL;Q8UKG4, Q9WWC7. TrEMBBL;Q7W456(66% identity). Has PF02308;MgtC family;(IPR003416, MgtCSapB_transpt):The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known. No Signal peptide or TMH reported present.; Family membership
YP_933328.1	Protein ygaD. TREMBL:Q7W761: 58% identity, 68% similarity CinA is a DNA damage- or competence-inducible protein that is polycistronic with recA in a number of species. Several bacterial species have a protein consisting largely of the C-terminal domain of CinA but lacking the N-terminal domain. InterPro: Competence-damaged protein InterPro: IPR008136; CinA_C. Pfam: PF02464 cinA_cterm: competence/damage-inducible No Signal peptide (Signal P predicted) No transmembrane helices; Function unclear
YP_933329.1	Conserved hypothetical membrane protein. Homology to smb20339 of S. meliloti of 30% (trembl|Q92WL4(SRS)). No domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein
YP_933330.1	39%
YP_933331.1	Conserved hypothetical membrane protein. Homology to CC2898 of Caulobacter crescentus of 56% (trembl|Q89WY3(SRS)). No domains predicted. No signal peptide. 4 TMHs; Conserved hypothetical protein
YP_933332.1	Hypothetical secreted protein. No significant homology over the entire protein length with the data bank. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); Ferredoxin (IPR001041); NADH: cytochrome b5 reductase (IPR001834). Pfam: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain. signal peptide. no TMHs
YP_933333.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide. 1 TMHs
YP_933334.1	Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. ilvC: ketol-acid reductoisomerase; Function unclear
YP_933335.1	Di-heme cytochrome c peroxidase MauG, required for the synthesis of the tryptophan tryptophylquinone (TTQ) prosthetic group of MADH in P.denitrificans . INVOLVED IN METHYLAMINE METABOLISM. ESSENTIAL FOR THE MATURATION OF THE BETA SUBUNIT OF MADH PRESUMABLY VIA A STEP IN THE BIOSYNTHESIS OF TRYPTOPHAN TRYPTOPHYLQUINONE (TTQ) THE COFACTOR OF MADH. urease_gam: urease gamma subunit; High confidence in function and specificity
YP_933336.1	Conserved hypothetical secreted protein. Homology ebA6930 of Azoarcus EbN1 of 31% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_933337.1	DNA-3-methyladenine glycosylase 1 (3-methyladenine DNA glycosidase 1) (3MEA DNA glycosylase 1). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE OR 7-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. CAN RELEASE ETHYLATED AND PROPYLATED BASES FROM DNA IN ADDITION TO 3-METHYLADENINE. TIGR00274: glucokinase regulator-related.; High confidence in function and specificity
YP_933338.1	Probable NADH dehydrogenase. Homology to ndh of P. fluorescens of 45% (trembl|Q9KGX09 TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; High confidence in function and specificity
YP_933339.1	Transcriptional regulator, LysR family,; Specificity unclear
YP_933340.1	Hypothetical protein sharing 76% similarity(61% identity) with Hypothetical protein [Thauera aromatica]TrEMBl O87938. Has pfam06980, DUF1302 domain,Protein of unknown function (DUF1302). This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas.(IPR010727) No Signal peptide or TMH being reported to be present.; Function unclear
YP_933341.1	Conserved hypothetical secreed protein. Homology to PA3081 of P.aeruginosa of 40% (tremble:Q9HZC7). Has DUF1329 domain(PF07044,IPRO10752). Protein of unknown function (DUF1329):This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs. Signal present.; Conserved hypothetical protein
YP_933342.1	Conserved hypothetical BNR domain protein. Homology to pp3201 of P. putida of 46% (trembl|Q88I01). InterPro: BNR repeat (IPR002860). Pfam: BNR repeat. BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide. no TMHs; Function unclear
YP_933343.1	Putative membrane protein MJ1562. TREMBL:Q88I00: 66% identity, 51% similarity The sterol-sensing domain (SSD) consists of approximately 180 amino acids organized into a cluster of five consecutive membrane-spanning domains and is found in proteins which have key roles in different aspects of cholesterol homeostasis or cholesterol-linked signalling such as sterol-regulated movement or the trafficking of specific cargoes. InterPro:IPR000731; SSD_5TM Found in :IPR003392: Patched family IPR004816: Hydroxymethylglutaryl-CoA reductase (NADPH Pfam:Patched:Patched family TIGRFAM:2A060602:transmembrane receptor Patch 2A0604s01: protein-export membrane pro TMHMM predicted 12 transmembrane helices; Family membership
YP_933344.1	Putative universal stress protein,; Conserved hypothetical protein
YP_933345.1	Methyl-accepting chemotaxis protein,; Specificity unclear
YP_933346.1	Transcriptional regulatory protein lapR. In Pseudomonas sp. strain KL28 the genes, designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. The lap genes are located in a 13.2 kb region with 14 ORFs in the order lapRBKLMNOPCEHIFG and with the same transcriptional orientation. The lapR gene is transcribed independently and encodes a member of the XylR/DmpR positive transcriptional regulators. Similarity to SWISSPROT: sprot|XYLR_PSEPU (45% Pseudomonas putida, XylR) / TREMBL: trembl|Q7WYF6 (63% Pseudomonas strain KL28,LapR) InterPro: IPR002078 Sig54_interact. IPR004096 V4R. IPR003593 AAA_ATPase. IPR002197 HTH_Fis. Pfam: PF02954 HTH_8. PF00158 Sigma54_activat. PF02830 V4R. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_933347.1	plant type ferredoxin like protein cofactor: binds 1 2fe-2s cluster (by similarity). Pfam: fer2 2Fe-2S iron-sulfur cluster binding do; Function unclear
YP_933348.1	In Pseudomonas sp. strain KL28 the genes,designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. The lap genes are located in a 13.2 kb region with 14 ORFs in the order lapRBKLMNOPCEHIFG and with the same transcriptional orientation. Catechol 2,3-dioxygenase LapB,; High confidence in function and specificity
YP_933349.1	Phenol 2-monooxygenase p0 component,; High confidence in function and specificity
YP_933350.1	Phenol hydroxylase p1 protein. Catabolizes phenol and some of its methylated derivates. P1 is required for growth on phenol and for in vitro phenol hydroxylase activity. Similar to SWISSPROT: sprot|DMPL_PSESP (52% Pseudomonas sp. (strain CF600), DmpL) / TREMBL: trembl|Q7WYF3 (67% Pseudomonas sp. KL28, LapL) InterPro: IPR003430 Phenol_Hydrox. Pfam: PF02332 Methane/Phenol/Toluene Hydroxylase. Part of the lap operon: In Pseudomonas sp. strain KL28 the genes,designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. The lap genes are located in a 13.2 kb region with 14 ORFs in the order lapRBKLMNOPCEHIFG and with the same transcriptional orientation.; High confidence in function and specificity
YP_933351.1	Phenol 2-monooxygenase p2 component,; High confidence in function and specificity
YP_933352.1	Phenol 2-monooxygenase p3 component,; High confidence in function and specificity
YP_933353.1	Phenol 2-monooxygenase p4 component,; High confidence in function and specificity
YP_933354.1	Phenol hydroxylase P5 protein (EC 1.14.13.7) (Phenol 2-monooxygenase P5 component). Probable electron transfer from NADPH via FAD and the 2Fe-2S center to the oxygenase activity site of the enzyme.; High confidence in function and specificity
YP_933355.1	Conserved hypothetical protein. Homology to an orf of Vibrio vulnificus of 41% (gi|51242695|gb|AAT99285.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_933356.1	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase,; High confidence in function and specificity
YP_933357.1	Conversion of 2-hydroxypent-2,4-dienoate into 4-hydroxy-2-oxopentanoate, involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. Belongs to the todj/xyli/xylj/hpcg family, TREMBL:Q93JW5 (62% identity); SWISSPROT:P23107 (58% identity). Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity
YP_933358.1	Conversion of 4-oxalocrotonate into 2-oxopent-4-enoate, involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. Belongs to the todJ/xylI/xylJ/hpcG family, TREMBL:Q8RQD3 (56% identity); SWISSPROT:P23107. Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity
YP_933359.1	4-oxalocrotonate isomerase,; High confidence in function and specificity
YP_933360.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_933361.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_933362.1	Catechol 2,3-dioxygenase XylE catalyzes the ring cleavage of catechol and some substituted catechols. Similar to pir|JE0112 (52%), to trembl|Q45459 (48%)and to sprot|XYE2_PSEPU (50%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ProDom (PD000977): Extradiol ring-cleavage dioxygenase; Specificity unclear
YP_933363.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q82N83 (22% identity); TREMBL:Q9F8V0 (21% identity). Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933364.1	Putative tautomerase Weak Homology with others similar proteins. Has 2 copies of PF01361, Tautomerase enzyme;IPR004370, Taut;This family includes the enzyme 4-oxalocrotonate tautomerase Q01468 that catalyses the ketonisation of 2-hydroxymuconate to 2-oxo-3-hexenedioate.
YP_933365.1	Hypothetical protein. No homology of the entire protein to the data base. Has (IPR002790)PF01936;Protein of unknown function DUF88; This highly conserved bacterial protein has no known function. The alignment contains many conserved aspartates, suggesting an enzymatic function such as an endonuclease or glycosyl hydrolase (Bateman A pers. obs). No Signal peptide or TMH present.
YP_933366.1	Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs.; Family membership
YP_933367.1	Integrase. INTEGRASE IS NECESSARY FOR INTEGRATION OF THE PHAGE INTO THE HOST GENOME BY SITE-SPECIFIC RECOMBINATION. IN CONJUNCTION WITH EXCISIONASE INTEGRASE IS ALSO NECESSARY FOR EXCISION OF THE PROPHAGE FROM THE HOST GENOME.; Specificity unclear
YP_933368.1	Hypothetical protein , 27% identity to TrEMBL;Q84EQ6. No domains, repeats, motifs or features present.
YP_933369.1	Hypothetical protein. No matches in the database. No domains, repeats, motifs or features present.
YP_933370.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_933371.1	Hypothetical protein. Very weak homology with hits in the database. No domains, repeats, motifs or features present.
YP_933372.1	Hypothetical protein, very weak homology with hits in the Database. No Motifs,domains, or Signal peptide present.
YP_933373.1	Putative Hypothetical protein. Very weak homology with hits in the Database. No signficant domains, motifs or Signal Peptide present.
YP_933374.1	Putative protease encoded ATP-dependent Clp protease family protein similar(30 Identity,45% similarity in function) to TrEMBL:Q8X866. IPR001907. Has pfam00574,CLP_protease, Clp protease. The Clp protease has an active site catalytic triad. In E. coli Clp protease, ser-111,his-136 and asp-185 form the catalytic triad. One member has lost all of these active site residues and is therefore inactive. Some members contain one or two large insertions. Peptidase family S49 domain present. Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). PF00574;CLP_protease PR00127;CLPPROTEASEP PS00381;CLP_PROTEASE_SER PS00382;CLP_PROTEASE_HIS TIGR00493;clpP No Signal peptide or TMH being reported as present.; High confidence in function and specificity
YP_933376.1	Hypothetical phage tail tape measure protein. Controls phage tail length no signal peptide. no TMH
YP_933377.1	Hypothetical protein, 26% Identity to TrEMBL;Q9PFZ1. No domains, repeats, motifs or features could be predicted above threshold.
YP_933378.1	dTDP-4-dehydrorhamnose 35-epimerase (EC 5.1.3.13) (dTDP-4-keto-6- deoxyglucose 35-epimerase) (dTDP-L-rhamnose synthetase). InterPro: dTDP-4-dehydrorhamnose 35-epimerase; High confidence in function and specificity
YP_933379.1	Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (dTDP-glucose synthase) (dTDP-glucose pyrophosphorylase).; High confidence in function and specificity
YP_933380.1	Region start changed from 2059335 to 2059254 (-81 bases)
YP_933381.1	dTDP-glucose 46-dehydratase (EC 4.2.1.46). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity
YP_933382.1	Conserved hypothetical secreted protein. Homology to pp4172 of P. putida of 33% (trembl|Q88FC6). Pfam: DUF534 This is a family of putative secreted proteins of unknown function. signal peptide. no TMHs; Conserved hypothetical protein
YP_933383.1	Conserved hypothetical signaling protein. Homology to Daro03001110 of Dechloromonas aromatica of 33% (gi|46141071|ref|ZP_00203851.1|(NBCI ENTREZ)). InterPro: IPR003660 HAMP. IPR000160 GGDEF. Pfam: PF00563 EAL domain. PF00672 HAMP. PF00990 GGDEF domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. Signal P reporting signal peptide. TMHMM reporting 3 transmembrane helices.; Conserved hypothetical protein
YP_933384.1	Conserved hypothetical secreted protein. TREMBL:O86370 (36% identity); TREMBL:Q7U0W8 (36% identity). No domains predicted. SignalP reporting signal peptide. No TMHs; Conserved hypothetical protein
YP_933385.1	Similar to TREMBL:Q82US4 (29% identity). Pfam (DUF214): Predicted permease. TMHMM predicting 10 transmembrane helices.; Specificity unclear
YP_933386.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q89X55 (42% identity); SWISSPROT:P31219 (40% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter.; Family membership
YP_933387.1	Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 30% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership
YP_933388.1	Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 35% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership
YP_933389.1	Putative oxidoreductase precursor, 27% identity (38% similarity) to TrEMBL;Q6N3F3. TrEMBL;Q9RI54. Has PF00070;Pyridine nucleotide-disulphide oxidoreductase; IPR001327 FAD_pyr_redox:This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. Has PF01593,Flavin containing amine oxidoreductase;(IPR002937,Amino_oxidase):This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters,neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Has PF01494, FAD binding domain;(IPR002938 Moxy_FAD_binding);This domain is involved in FAD binding in a number of enzymes.; Family membership
YP_933390.1	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl|Q8XXV5). no domain predicted. no signal peptide. no TMHs
YP_933391.1	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583 ;Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs
YP_933392.1	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity
YP_933393.1	8-amino-7-oxononanoate synthase (EC 2.3.1.47) (AONS) (8-amino-7- ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase). InterPro: Aminotransferases class-I bioF: 8-amino-7-oxononanoate synthase; High confidence in function and specificity
YP_933394.1	BioH protein.Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). Seems to be implicated in the early steps of biotin biosynthesis.; Function unclear
YP_933395.1	Biotin synthesis protein bioC. bioc is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin.; Specificity unclear
YP_933396.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_933397.1	Region start changed from 2079087 to 2078673 (-414 bases)
YP_933398.1	Conserved hypothetical membrane protein. Homology to PA1044 of P. aeruginosa of 44% (trembl|Q9I4T0). No domains predicted. Signal peptide. 3 TMHs; Conserved hypothetical protein
YP_933399.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_933400.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
YP_933401.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
YP_933402.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_933403.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_933404.1	Probable outer membrane protein. Homology to ompH of Y. enterocolitica of 30% (sprot|OMPH_YEREN). Pfam: outer membrane protein (OmpH-like) signal peptide no TMHs; High confidence in function and specificity
YP_933405.1	InterPro: Bacterial surface antigen (D15); Function unclear
YP_933406.1	Conserved hypothetical membrane-associated zinc metalloprotease. Homology to ne1711 of N. europaea of 51% (trembl|Q82U02). Tigrfam: TIGR00054: membrane-associated zinc metalloprotease. Pfam: PDZ domain (Also known as DHR or GLGF). no signal peptide. 4 TMHs; Family membership
YP_933407.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_933408.1	Phosphatidate cytidylyltransferase :- catalytic activity ctp + phosphatidate = diphosphate + cdp-diacylglycerol. pathway :-phospholipid biosynthesis. Entry name:- CDSA_ECOLI Primary accession number :- P06466 InterPro:- IPR000374; PC_trans. Identities = 89/252 (35%) Pfam PF01148; CTP_transf_1; 1. Number of predicted TMHs: 7 Prediction: Signal peptide Signal peptide probability: 1.0; Family membership
YP_933409.1	Undecaprenyl pyrophosphate synthetase :- Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of the carrier lipid for peptidoglycan synthesis (By similarity). Identities = 124/228 (54%) Entry name SWISSPROT:UPPS_ECOLI Prim. accession # P60472 InterPro :- IPR001441; UPP_synth. Pfam:- PF01255; UPP_synthetase; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.0; Family membership
YP_933410.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_933411.1	Catalyzes the phosphorylation of UMP to UDP
YP_933412.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_933413.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_933414.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_933415.1	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein
YP_933416.1	Conserved hypothetical membrane protein. Homology to RPA0231 of Rhodopseudomonas palustris of 39% (trembl|Q6ND78). Has PF03350,(IPR005134) Uncharacterized protein family, UPF0114: This conserved hypothetical protein family with four predicted transmembrane regions is found in E. coli, Haemophilus influenzae, and Helicobacter pylori, among completed genomes. No signal peptide. 3 TMHs
YP_933417.1	Conserved hypothetical protein. Homology to pp1134 of P. putida of 77% (trembl|Q88NS1). Pfam: Phytoene dehydrogenase related enzyme. no signal peptide. no TMHs
YP_933418.1	C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity
YP_933419.1	C4-dicarboxylate transport sensor protein,; High confidence in function and specificity
YP_933420.1	Conserved hypothetical secreted protein. Homology to blr1303 of B. japonicum of 38% (trembl|Q89UV6(SRS)) No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_933421.1	Conserved hypothetical membrane protein. Homology to so0455 of S. oneidensis of 65% (trembl|Q8EJK8). Tigrfam: dctM: TRAP dicarboxylate transporter-DctM subunit. Pfam: TRAP C4-dicarboxylate transport (Dct) system permease DctM subunit. This domain represents a conserved region located towards the N terminus of the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease. no signal peptide. 17 TMHs; Conserved hypothetical protein
YP_933422.1	Conserved hypothetical secreted protein. Homology to pp3954 pf P. putida of 64% (trembl|Q88FX3). no domains predicted. singal peptide. TMH in signal peptide; Conserved hypothetical protein
YP_933423.1	Hypothetical protein MG039 homolog (D09_orf384). D-amino acid oxidase (EC: 1.4.3.3) (DAMOX or DAO) is an FAD flavoenzyme that catalyzes the oxidation of neutral and basic D-amino acids into their corresponding keto acids. DAOs have been characterized and sequenced in fungi and vertebrates where they are known to be located in the peroxisomes. InterPro: D-amino acid oxidase Putative conserved exported protein. TREMBL:Q7WG75: 55% identity,65% similarity. TREMBLnew:CAE29609. Pfam:NAD binding FAD dependent oxidoreductase. TIGRFAM:UDP-GALP mutase. Signal P predicted signal peptide and TMHMM predicted transmembrane helices. gidA: glucose-inhibited division prot; Specificity unclear
YP_933424.1	Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of P. aeruginosa of 62% (trembl|Q9RBF6) Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity
YP_933425.1	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 66% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity
YP_933426.1	Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity
YP_933427.1	Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs
YP_933428.1	CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q98HG5 Prim. accession # Q98HG5 Identities = 253/397 (63%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership
YP_933429.1	Transcriptional regulator, LysR family,; Specificity unclear
YP_933430.1	Hypothetical protein. no homology over the entire protein. no domain structure no signal peptide no TMHs
YP_933431.1	Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or3)-enoyl-CoA + H2O. Entry name TREMBL:Q7VU52 Prim. accession # Q7VU52 Identities = 124/266 (46%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; High confidence in function and specificity
YP_933432.1	Conserved hypothetical protein. Homology to orf5 of Azoarcus evansii of 78% (tremble:Q93FB4). Pfam: Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. No signal peptide. No TMHs
YP_933433.1	TREMBL:Q89PR6: 50% identity; 71% similarity Probable 4-hydroxybenzoyl-CoA thioesterase . InterPro:IPR008272; 4HBcoA_thiost_AS Pfam:4HBT:4-hydroxybenzoyl-CoA thioesterase TIGR00051: conserved hypothetical protein No transmembrane helices; Function unclear
YP_933434.1	Glutaryl-CoA dehydrogenase mitochondrial precursor CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q88RH2 Prim. accession # Q88RH2 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Number of predicted TMHs: 0; Family membership
YP_933435.1	Catalysis of the reaction:- acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name TREMBL:Q98BT9 Prim. accession # Q98BT9 InterPro IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. Number of predicted TMHs: 0; Family membership
YP_933436.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_933437.1	Probable beta-hydroxyacyl-CoA dehydrogenase. Homology to abmB of A. evansii of 79%. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase. No signal peptide. No TMHs.; Specificity unclear
YP_933438.1	catalyzes the conversion of salicylyl-CoA to gentisyl-CoA
YP_933439.1	Putative MarR-family transcriptional regulator,; Family membership
YP_933440.1	Putative AraC-family transcriptional regulator,; Family membership
YP_933441.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q9AQN5 (39% identity); TREMBL:Q987X7 (35% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933442.1	Putative styrene monooxygenase. Homology to styA of P. fluorescens of 25% (TREMBL:O06834) Encode a styrene monooxygenase responsible for the transformation of styrene to epoxystyrene Pfam: FAD binding domain no signal peptide no TMHs; Family membership
YP_933443.1	Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) (NTA monooxygenase component B) (NTA-MO B). HYDROXYLATION OF NITRILOTRIACETATE. TREMBL:Q93NA5:48% identity, 62% similarity InterPro: IPR002563; Flavin_Reduct. IPR009002; FMN_binding. Pfam:PF01613; Flavin_Reduct Non-secretory protein with low signal peptide probability (0.002) Absence of transmembrane helices; High confidence in function and specificity
YP_933444.1	Conserved hypothetical membrane protein. Homology to PP4294 of P. putida of 67% (trembl|Q88F06). Has PF05661, Protein of unknown function (DUF808);IPR008526;This family consists of several bacterial proteins of unknown function. no signal peptide. 5 TMHs; Conserved hypothetical protein
YP_933445.1	Putative glucose dehydrogenase alpha subunit. Homology to gdhAlpha of B. cepacia of 28% (trembl|Q8GQE7). InterPro: NAD binding site (IPR000205); UBA/THIF-type NAD/FAD binding fold (IPR000594), $Fe-4s ferredoxin, ion-sulfur binding domain (IPR001450) Pfam: GMC oxidoreductase no signal peptide no TMHs gid: gid protein; Function unclear
YP_933446.1	Hypothetical secreted protein. No good homology with hits in the database. No domains predicted. Signal peptide present. No TMHs
YP_933447.1	Putative flavin:NADH reductase ycdH (EC 1.6.8.-). Catalyzes the reduction of free flavins (FMN FAD and riboflavin) by NADH (By similarity). TREMBL:Q8RLG2: 41% identity, 60% similarity InterPro: Flavin reductase-like domain InterPro: IPR002563; Flavin_Reduct. IPR009002; FMN_binding. Pfam PF01613; Flavin_Reduct gmhA: phosphoheptose isomerase No signal peptide Absence of transmembrane helices; Function unclear
YP_933448.1	Conserved hypothetical protein. Homology to mll3445) of M. loti of 71% (trembl|Q98G8). InterPro: Bacterial luciferase (IPR002103). Pfam: Luciferase-like monooxygenase. no signal peptide. no TMHS
YP_933449.1	Putative AraC-family transcriptional regulator,; Family membership
YP_933450.1	Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padB of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA5393(KEGG)). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655). Pfam: Molypdopterin oxidoreductase; Molydopterin dinucleotide binding domain. no signal peptide. no TMHs; Function unclear
YP_933451.1	Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padC of A. evansiin of 61% (trembl|Q8L3B5). Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes (By similarity). Pfam: 4Fe-4S binding domain. Tigrfam: napF: ferredoxin-type protein NapF. no signal peptide. no TMHs; Family membership
YP_933452.1	Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padD of A. evansii of 43% (trembl|Q8L3B4(SRS) Pfam: DMSO reductase anchor subunit (DmsC) The terminal electron transfer enzyme Me2SO reductase of Escherichia coli is a heterotrimeric enzyme composed of a membrane extrinsic catalytic dimer (DmsAB) and a membrane intrinsic polytopic anchor subunit (DmsC). no signal peptide. 8 TMHs; Family membership
YP_933453.1	Putative AraC-family transcriptional regulator,; Family membership
YP_933454.1	Conserved hypothetical membrane protein. Homology to Daro03003315 of Dechloromonas aromatica of 48% (gi|53729651|ref|ZP_00348492.1|(NBCI ENTREZ)). InterPro: BNR repeat (IPR002860) Pfam: BNR repeat BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. no singal peptide. 1 TMHs
YP_933455.1	Probable Putative membrane protein MJ1562. TREMBL:Q8G9A8:32% identity, 52% similarity InterPro:IPR000873; AMP-bind. IPR002114; HPr_SerP_S Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide present (Signal P predicted) TMH's 10 (TMHMM predicted); Family membership
YP_933456.1	Conserved hypothetical secreted protein. Homology to Daro03003313 of Dechloromonas aromatica of 60% (gi|53729649|ref|ZP_00149978.2|(NBCI ENTREZ)). Has PF06980, Protein of unknown function (DUF1302);IPR010727,DUF1302;This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. Signal peptide present. No TMHs; Conserved hypothetical protein
YP_933457.1	Conserved hypothetical secreted protein. Homology to Raeut03000741 of Ralstonia eutropha of 45% (gi|46131405|ref|ZP_00169583.2|(NBCI ENTREZ)). Pfam: Protein of unknown function (DUF1329). This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_933458.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933459.1	catalyzes the formation of indole-3-acetic acid from indole-3-acetamide
YP_933460.1	Putative amidase amiD; Family membership
YP_933461.1	TREMBLNEW:47357: 69% identity, 80% similarity. 2-hydroxy-6-oxo-6-phenylhexa-24-dienoate hydrolase. The alpha/beta hydrolase fold [1] is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices Pfam: Ndr family. TIGR00148: conserved hypothetical protein; High confidence in function and specificity
YP_933462.1	Putative Hydantoin racemase,28% Identity toTrEMBL;Q7NTB3,Q885G0,Q6YNI1. SProt;Q00924. Has PF01177,Asp/Glu/Hydantoin racemase;IPR001920, Asp/Glu_race; This family contains aspartate racemase, glutamate racemase,hydantoin racemase and arylmalonate decarboxylase. Aspartate racemase (EC: 5.1.1.13) and glutamate racemase (EC: 5.1.1.3) are two evolutionary related bacterial enzymes that do not seem to require a cofactor for their activity . Glutamate racemase, which interconverts L-glutamate into D-glutamate, is required for the biosynthesis of peptidoglycan and some peptide-based antibiotics such as gramicidin S. In addition to characterized aspartate and glutamate racemases, this family also includes a hypothetical protein from Erwinia carotovora and one from Escherichia coli (ygeA).Two conserved cysteines are present in the sequence of these enzymes. They are expected to play a role in catalytic activity by acting as bases in proton abstraction from the substrate.
YP_933463.1	Hypothetical protein SignalP reporting Non-secretory protein.
YP_933464.1	Reductase component OxoR, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation.; High confidence in function and specificity
YP_933465.1	Oxygenase component OxoO, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation.; Function unclear
YP_933466.1	Conserved hypothetical flavin reductase. Homology to rsc0763 of R. solanacearum of 43% (TREMBL:Q8Y1C7). Pfam: Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. no signal peptide. no TMHs; Conserved hypothetical protein
YP_933467.1	Conserved Hypothetical protein has strong similarity 70% and 51% identity to PUTATIVE OXYGENASE SUBUNIT PROTEIN [Ralstonia solanacearum GMI1000],TrEMBL:Q8XYC1, which has IPR003042; Rng_mnoxygenase and IPR001327; FAD_pyr_redox domain which is absent in this case. No Signal peptide or TMH being reported as present.; Function unclear
YP_933468.1	Putative AraC-family transcriptional regulator,; Family membership
YP_933469.1	Putative AraC-family transcriptional regulator,; Family membership
YP_933470.1	Methylcatechol 2,3-dioxygenase, TodE, is involved in the degradation of toluene. Similar to sprot|TODE_PSEPU (38%) and to trembl|Q52031 (36%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Specificity unclear
YP_933471.1	Conserved hypothetical protein. Homology to Daro03003325 of Dechloromonas aromatica of 52% (gi|53729660|ref|ZP_00348498.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_933472.1	TREMBL:Q93JW6: 67% identity, 81% similarity. 2-hydroxymuconic semialdehyde hydrolase (HMSH). hydrolysis of C-C bonds in ketonic substances CONVERSION OF 2-HYDROXYMUCONIC ACID SEMIALDEHYDE TO 2-HYDROXYPENT-24-DIENOATE. Pfam: abhydrolase: alpha/Beta hydrolase fold; thioesterase domain Absence of transmembrane helices (TMHMM predicted) prfB: peptide chain release factor 2; High confidence in function and specificity
YP_933473.1	GntR family transcriptional regulator,; High confidence in function and specificity
YP_933474.1	Conserved hypothetical protein. Homology to an orf of Rhizobium sp. NGR234 of 50% (tremblnew|AAQ87234(SRS)). No domain predicted. No signal peptide or TMH reported present.
YP_933475.1	SPROT:ADH1_BACST:31% identity; 45% similarity Alcohol dehydrogenase (EC 1.1.1.1) (ADH-T). THERMOSTABLE NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. an alcohol + nad(+) = an aldehyde or ketone + nadh. cofactor:binds 2 zinc ions per subunit (by similarity). InterPro: IPR002328; ADH_zinc. IPR002085:Adh_zn_family. Pfam:PF00107; ADH_zinc_N tdh: L-threonine 3-dehydrogenase; Specificity unclear
YP_933476.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_933477.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_933478.1	This family consist of various hydratases and 4-oxalocrotonate decarboxylases which are involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds, TREMBL:Q51981 (54% identity); SWISSPROT:P77608 (50% identity). InterPro (IPR002607): Hydratase/decarboxylase Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity
YP_933479.1	catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family
YP_933480.1	Hypothetical protein Rv2715/MT2788/Mb2734. TREMBL:Q9KH20: 58% identity, 73% similarity 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase; OhpC [Rhodococcus sp.] Catalysis of the reaction: 2-hydroxy-6-keto-nona-2,4-dienedioate + OH- = cis-2-hydroxypenta-2,4-dienoate + succinate. Pfam: alpha/ beta hydrolase; Ndr family; B12 binding domain. No signal peptide (Signal P predicted) or transmembrane helices (TMHMM predited) TIGRFAM: Co A. E activ TIGR00044: conserved hypothetical protein; Family membership
YP_933481.1	Oxygenase component OxoO, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit arcC: carbamate kinase; Function unclear
YP_933482.1	TREMBL:Q89PP9: 66% identity, 79% similarity. InterPro:IPR007325; Cyclase. Pfam:PF04199; Cyclase No signal peptide present. Absence of trans-membrane helices (TMHMM predicted).; Function unclear
YP_933483.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_933484.1	Conserved hypothetical indolepyruvate oxidoreductase, alpha subunit. Homology to mlr5448 of M. loti of 69% (trembl|Q98BS4). CATALYZES THE FERREDOXIN-DEPENDENT OXIDATIVE DECARBOXYLATION OF ARYLPYRUVATES (BY SIMILARITY). no signal peptide. no TMHs; Conserved hypothetical protein
YP_933485.1	Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
YP_933486.1	Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 42% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership
YP_933487.1	Hydroxylase large component of 1,2-dioxygenase complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBb. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyY: Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB).; High confidence in function and specificity
YP_933488.1	Hydroxylase large component of 1,2-dioxygenase complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBa. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyX: Benzoate 12-dioxygenase alpha subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). THE BETA SUBUNIT MAY BE RESPONSIBLE FOR THE SUBSTRATE SPECIFICITY OF THE ENZYME. InterPro: Aromatic-ring-hydroxylating dioxygenase beta subunit; High confidence in function and specificity
YP_933489.1	Similar to TREMBL:Q89PS8 (59% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase. Pfam (PF00501): AMP-binding enzyme.; Function unclear
YP_933490.1	Entry name TREMBL:Q89PQ1 Prim. accession # Q89PQ1 Identities = 241/381 (63%) Thiolase, N-terminal domain (Pfam predicted) Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0
YP_933491.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear
YP_933492.1	TREMBL:Q8XYC3: 64% identity, 75% similarity Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form a part of the active site. InterPro:IPR007325; Cyclase. Pfam: PF04199; Cyclase Absence of signal peptide. Absence of transmembrane helices; Function unclear
YP_933493.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q7WG84 (46% identity); SWISSPROT:P17611 (30% identity). Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933494.1	The transport of branched-chain amino acids in P. aeruginosa is mediated by two distinct systems, the leucine, isoleucine, and valine I and II transports systems. Periplasmic binding proteins are found to participate in the transport of amino acids, sugars, and ions. BraC is the structural gene for periplasmic binding proteins in P. aeruginosa. Similar to trembl|Q9RYP6 (49%) and to sprot|BRAC_PSEAE (22%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_933495.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q8XRX6 (55%) and to trembl|Q7WCY3 (53%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting nine Tmhelix.; Specificity unclear
YP_933496.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (52%) and to trembl|Q89CG4 (45%). Pfam (PF00005): ABC transporter Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop) TMHMM reporting nine Tmhelix.; Specificity unclear
YP_933497.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (66%) and to trembl|Q89PQ7 (62%). Smart: AAA ATPases; Specificity unclear
YP_933498.1	Putative 2-dehydropantoate 2-reductase (EC 1.1.1.169) (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). apbA_panE: 2-dehydropantoate 2-reductase; Specificity unclear
YP_933499.1	41% Aldolase_II_N. Class II Aldolase and Adducin N-terminal domain Pfam: PF00596; Aldolase_II; 1. fucA: L-fuculose phosphate aldolase; High confidence in function and specificity
YP_933500.1	Acetyl-coenzyme A synthetase enables the cell to use acetate during aerobic growth to generate energy via the tca cycle, and biosynthetic compounds via the glyoxylate shunt. acetylates chey, the response regulator involved in flagellar movement and chemotaxis. Entry name SWISSPROT:ACSA_ECOLI Prim. accession # P27550 Identities = 145/546 (26%) Pfam PF00501; AMP-binding; 1. InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 1. Number of predicted TMHs: 0; Family membership
YP_933501.1	Putative transcriptional activatory protein BadR (Benzoate anaerobic degradation regulator). Similar to SWISSPROT: sprot|BADR_RHOPA (25% Rhodopseudomonas palustris, transcriptional activatory protein BadR (benzoate anaerobic degradation regulator)) InterPro: IPR000835 HTH_MarR. Pfam: PF01047 MarR family.; Family membership
YP_933502.1	Catalyzes the phosphorolytic cleavage of 6-oxopurine nucleosides
YP_933503.1	GTP-binding elongation factor,; High confidence in function and specificity
YP_933504.1	UTP--glucose-1-phosphate uridylyltransferase 1 (EC 2.7.7.9) (UDP- glucose pyrophosphorylase 1) (UDPGP 1) (Alpha-D-glucosyl-1-phosphate uridylyltransferase 1) (Uridine diphosphoglucose pyrophosphorylase 1). InterPro: ADP-glucose pyrophosphorylase ispD: 4-diphosphocytidyl-2C-methyl-D-er; High confidence in function and specificity
YP_933505.1	DNA ligase (Polydeoxyribonucleotide synthase [NAD+]). This protein catalyzes the formation of phosphodiester linkages between 5-phosphoryl and 3-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. TIGRFAM: dnlj: DNA ligase NAD-dependent.; High confidence in function and specificity
YP_933506.1	Conserved hypothetical membrane protein. Homology to ne2283 of N. europaea of 35% (trembl|Q82SM8(SRS)). Pfam: ZipA, C-ternial FtsZ-binding domaine. This family represents the ZipA C-terminal domain. ZipA is involved in septum formation in bacterial cell division. Its C-terminal domain binds FtsZ, a major component of the bacterial septal ring. The structure of this domain is an alpha-beta fold with three alpha helices and a beta sheet of six antiparallel beta strands. The major loops protruding from the beta sheet surface are thought to form a binding site for FtsZ. no singal peptide. 1 TMH; Conserved hypothetical protein
YP_933507.1	Chromosome partition protein smc. PLAYS AN IMPORTANT ROLE IN CHROMOSOME STRUCTURE AND PARTITIONING. ESSENTIAL FOR CHROMOSOME PARTITION. InterPro: SMC family C-terminal domain; High confidence in function and specificity
YP_933508.1	catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate
YP_933509.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
YP_933510.1	Tfp pilus retraction protein pilU, probable involved in twitching motility mechanism,; Specificity unclear
YP_933511.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_933512.1	involved in methylation of ribosomal protein L3
YP_933513.1	Putative Response regulator rcp1. Forms a two-component system with cph1 in which it acts as reciever substrate. Similar to SWISSPROT: sprot|RCP1_SYNY3 (30% Synechocystis sp., Rcp1) Pfam: PF00072 Response_reg.; Function unclear
YP_933514.1	Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384 ; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present.
YP_933515.1	Ferredoxin 2Fe-2S. Homology to fdx of E. coli of 70% (sprot|FER_ECOLI ). Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Although the function of this ferredoxin is unknown it is probable that it has a role as a cellular electron transfer protein. Involved in the in vivo assembly of the Fe-S clusters in a wide variety of iron- sulfur proteins. InterPro: Ferredoxin (IPR001055); Adrenodoxin (IPR001055) Pfam: 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_933516.1	involved in the maturation of iron-sulfur cluster-containing proteins
YP_933517.1	J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins
YP_933518.1	Putative regulatory Protein yfhF, 72% identity (82% similarity) to TrEMBL;P36539 of E.coli. Has PF01521, HesB-like domain;(IPR000361, HesB_yadR_yfhF); This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation.; High confidence in function and specificity
YP_933519.1	NifU-related protein. Homology to iscU of A. vinelandii of 79% (trembl|O31270). IscU is a homologue of the N-terminal region of NifU, an protein MAY BE INVOLVED IN THE FORMATION OR REPAIR OF [FE-S] CLUSTERS PRESENT IN IRON-SULFUR PROTEINS mostly found in nitrogen-fixing bacteria. InterPro: NifU-like N terminal domain (IPR002871) Pfam: NifU-like N-terminal domain no signal peptide no TMHs; High confidence in function and specificity
YP_933520.1	Cysteine desulfurase (NifS protein homolog). Homology to iscS of E. coli of 72% (sprot|ISCS_ECOLI). Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Functions as a sulfur delivery protein for nad, biotin and fe-s cluster synthesis. Pfam: Aminotransferase class V no signal peptide no TMHs; High confidence in function and specificity
YP_933521.1	Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership
YP_933522.1	RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic acid binding motif.; Family membership
YP_933523.1	Probable serine acetyltransferase (EC 2.3.1.30). Homology to cysE of B. subtilis of 48% (sprot|CYSE_BACSU). no signal peptide no TMHs; Family membership
YP_933524.1	tRNA/rRNA methyltransferase; Specificity unclear
YP_933525.1	Inositol-1-monophosphatase (EC 3.1.3.25) (IMPase) (Inositol-1- phosphatase) (I-1-Pase).May act by enhancing the synthesis or degradation of phosphorylated messenger molecules. Catalytic activity: myo-inositol 1-phosphate + h(2)o = myo- inositol + phosphate. 52% Inositol_P. Pfam:PF00459; inositol_P; 1.; High confidence in function and specificity
YP_933526.1	Conserved hypotheticalsecreted protein. Homology to bll4707 of B.japonicum of 40% (tremble:Q89L41). No domains predicted. Signal P reporting signal peptide present. No TMH reported to be present.; Conserved hypothetical protein
YP_933527.1	Family membership
YP_933528.1	Conserved Hypothetical protein,[yoeB],69% identical(85% similarity) to SwissPort;P56605. TrEMBL;Q8FG53 Has PF05015, Plasmid maintenance system killer protein (IPR007711, Plasmid_killer) ;Several plasmids with proteic killer gene systems have been reported. All of them encode a stable toxin and an unstable antidote. Upon loss of the plasmid, the less stable inhibitor is inactivated more rapidly than the toxin, allowing the toxin to be activated. The activation of those systems result in cell filamentation and cessation of viable cell production. It has been verified that both the stable killer and the unstable inhibitor of the systems are short polypeptides. This family corresponds to the toxin. Has (IPR009614)PF06769, Protein of unknown function (DUF1224);This family consists of several short, hypothetical bacterial proteins of around 85 residues in length. The function of this family is unknown.
YP_933529.1	Conserved hypothetical acetyltransferase. Homology to glr3475 of G. violaceus of 40% (trembl|Q7NFP9). Pfam: Acetyltransferase (GNAT) family. no signal peptide. no TMHs; Family membership
YP_933530.1	Conserved hypothetical protein. Homology to plu0180 of P.luminescens of 37% (trembl:Q7N9X1). No domains predicted. No TMHs. No signal peptide.
YP_933531.1	Conserved hypothetical truncated transposase. Homology to Reut02001235 of Ralstonia metallidurans of 31% (gi|48772472|ref|ZP_00276814.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_933532.1	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank no domains predicted no signal peptide no TMHs
YP_933533.1	Conserved hypothetical transposase. Homology to ebB8 of Azoarcus sp. EbN1 of 91% (gnl|keqq|eba:ebB8(KEGG)). Pfam: IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition. No signal peptide. Probable 1 TMHs; Conserved hypothetical protein
YP_933534.1	Hypothetical truncated transposase. Homology to the N-terminus of ebA290 of Azoarcus sp. EbN1 of 92% (gnl|keqq|eba:ebA290(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_933535.1	Hypothetical truncated transposase. Homology to the C-terminus of ebA290 of Azoarcus sp. EbN1 of 67% (gnl|keqq|eba:ebA290(KEGG)). Pfam: Transposase IS66 family. No signal peptide. No TMHs
YP_933536.1	Hypothetical protein, very weak homology with hits in the database. Has No domains, repeats, motifs or features detected.
YP_933537.1	Hypothetical truncated transposase. Homology to the N-terminus of tnp16A of Azoarcus sp. EbN1 of 54% (gnl|keqq|eba:ebA690(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933538.1	Conserved hypothetical transposase helper protein. Homology to ebB98 of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebB98(KEGG)). Pfam: IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition. No signal peptide. No TMHs.; Conserved hypothetical protein
YP_933539.1	Conserved hypothetical protein. Homology to ebD29 of Azoarcus sp. EbN1 of 55% (gnl|keqq|eba:ebD29(KEGG)). no domains predicted. no signal peptide. no TMHs.
YP_933541.1	Conserved hypothetical protein. Homology to XAC2237 of X.axonopodis of 33% (trembl:Q8PKD8). No domain predicted. No TMHs. No signal peptide.
YP_933542.1	Conserved hypothetical protein. Homology to RL074 of Pseudomonas aeruginosa of 34% (trembl:Q7WXY6). No domains predicted. No TMHs. No singal peptide.
YP_933543.1	Hypothetical protein predicted by Glimmer/Gritica. No homology to the data bank. No domains predicted. No signal peptide. No TMHs
YP_933544.1	Probable replicase,functional similarity(67%) to TrEMBL Q6I6A6,PF04796;IPR006881 Has pfam04796, RepA_C domain, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood. No Signal peptide or TMH are reported to be present.; Specificity unclear
YP_933545.1	Probable replicase(repA),functional similarity(67%) to TrEMBL Q6I6A6,PF04796;IPR006881 Has pfam04796, RepA_C domain, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood. No Signal peptide or TMH are reported to be present.
YP_933546.1	Conserved hypothetical membrane protein. Homology to ebA436 of Azoarcus sp. EbN1 of 49% (gnl|keqq|eba:ebA436(KEGG)). No domains predicted. No signal peptide. TMHMM2 reporting presence of 2 TMH's.; Conserved hypothetical protein
YP_933547.1	Conserved hypothetical secreted protein. Homology to ebA439 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA439(KEGG)). No domains predicted. No TMHs signal peptide present.; Conserved hypothetical protein
YP_933548.1	Conserved hypothetical protein. No homology to a protein of similar size in the data base. No domains predicted. No TMHs. No signal peptide.
YP_933549.1	Hypothetical protein, 28% identity (45% similarity) to TrEMBL;Q7VHD7. Weak homology with hits in the Database spanning the entire lenghth of Protein. Has PF03235,Protein of unknown function DUF262; Interpro;IPR004919.; Function unclear
YP_933550.1	Hypothetical protein 27% identity to TrEMBL;Q7VHD8. Signal Peptide, or any known features not present.
YP_933551.1	DNA repair protein radC homolog.; High confidence in function and specificity
YP_933552.1	Hypothetical protein yfdR. The HD domain is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These enzymes appear to be involved in the nucleic acid metabolism, signal transduction and possibly other functions in bacteria,archaea and eukaryotes TREMBL:Q8HAA3: 41% identity,52% similarity InterPro:IPR003607; Met_phsphohydro. SMART:SM00471; HDc hstdl_phs_rel: histidinol phosphatase-r No signal peptide No transmembrane helices; Function unclear
YP_933553.1	Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs
YP_933554.1	Putative H repeat-associated protein PF01609 Transposase_11, Transposase DDE domain. Transposases are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda. SignalP reporting signal Peptide to be present No TMH reproted as present.; High confidence in function and specificity
YP_933555.1	Integrase. INTEGRASE IS NECESSARY FOR INTEGRATION OF THE PHAGE INTO THE HOST GENOME BY SITE-SPECIFIC RECOMBINATION. IN CONJUNCTION WITH EXCISIONASE INTEGRASE IS ALSO NECESSARY FOR EXCISION OF THE PROPHAGE FROM THE HOST GENOME. InterPro: Phage integrase; High confidence in function and specificity
YP_933556.1	This protein performs the mismatch recognition step during the DNA repair process
YP_933557.1	Spermidine synthase (Putrescine aminopropyltransferase),; Conserved hypothetical protein
YP_933558.1	DNA polymerase III epsilon chain. DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THE EPSILON SUBUNIT CONTAIN THE EDITING FUNCTION AND IS A PROOFREADING 3-5 EXONUCLEASE (BY SIMILARITY). InterPro: Exonuclease. TIGRFAM: dnaq: DNA polymerase III epsilon chain.; High confidence in function and specificity
YP_933559.1	Ribonuclease H (RNase H). This enzyme is an endonuclease that degrades the RNA of RNA-DNA hybrids specifically (By similarity).; High confidence in function and specificity
YP_933560.1	Similar to TREMBL:Q82XV9 (41% identity, generic methyl-transferase); TREMBL:Q7NYL9 (45% identity).
YP_933561.1	Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II). Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid.Similarity to bacterial stress protein TerD. 49% identity and 64% similarity to similar product from Nitrosomonas europaea ATCC InterPro: Metallo-beta-lactamase superfamily CoA_E_activ: CoA-substrate-specific enz; Family membership
YP_933562.1	Probable response regulator,; Specificity unclear
YP_933563.1	Probable REC/GGDEF-domain containing protein,; Function unclear
YP_933564.1	Region start changed from 2259236 to 2259431 (-195 bases)
YP_933565.1	Hypothetical ABC transporter ATP-binding protein yliA. PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q82S74: 52% identity, 64% similarity. InterPro: IPR003593; AAA_ATPase. No signal peptide No transmembrane helices. IPR003439; ABC_transporter. IPR010066; Oligo_HPY. Pfam:PF00005; ABC_tran; 2. ProDom: PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 2. TIGRFAMs TIGR01727; oligo_HPY mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity
YP_933566.1	Conserved hypothetical peptidyl-prolyl cis-trans isomerase. Homology to slyD of E. coli of 41% (sprot|SLYD_ECOLI) but around 30 aa at the C-terminus are missing. Peptidylprolyl isomerases accelerate protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) (IPR001179). Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase. no signal peptide. no TMHs; Family membership
YP_933567.1	Putative bacterioferritin comigratory protein. Homology to bcp of E. coli of 37% (srot:BCP_ECOLI) Interpro: Alkyl hydroperoxid reductase/ Thiol specific antioxidant / Mal Alergern (IPR000866) Pfam: AhpcC/TSA family no signal peptide no TMH; Family membership
YP_933568.1	Represses a number of genes involved in the response to DNA damage
YP_933569.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 4 TMHs
YP_933570.1	The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae,and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. Functions as a Na(+)/drug antiporter. These proteins have 12 probable TMS,TREMBL:Q7NXN3 (35% identity); SWISSPROT:Q9K015 (32% identity). Pfam (UPF0013): Uncharacterized membrane protein family. TIGRFAM (TIGR00797): matE. TMHMM reporting 11 transmembrane helices. TC (2.A.66.1.): The Multi Antimicrobial Extrusion (MATE) Family.; High confidence in function and specificity
YP_933571.1	Arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier). REDUCTION OF ARSENATE [AS(V)] TO ARSENITE [AS(III)]. THIS PROTEIN EXPANDS THE SUBSTRATE SPECIFICITY OF ARSAB PUMP WHICH CAN EXTRUDE ARSENITE AND ANTIMONITE TO ALLOW FOR ARSENATE PUMPING AND RESISTANCE. arsC: arsenate reductase; High confidence in function and specificity
YP_933572.1	Conserved hypothetical protein. Homology to rsc2890 of R. solanacearum of 53% (trembl|Q8XVE1). InterPro: PDZ domain (also known as DHR or GLGF)(IPR001478). Pfam: PDZ domain (also known as DHR or GLGF); M61 glycyl aminopeptidase PDZ domains are found in diverse signaling proteins in bacteria, yeasts, plants, insects and vertebrates. They may function in targeting signalling molecules to sub-membranous sites. Some PDZs have been shown to bind C-terminal polypeptides; others appear to bind internal (non-C-terminal) polypeptides. Different PDZs possess different binding specificities. Glycyl aminopeptidase is an unusual peptidase in that it has a preference for substrates with an N-terminal glycine or alanine. no signal peptide. no TMHs.; Family membership
YP_933573.1	Region start changed from 2272064 to 2271998 (-66 bases)
YP_933574.1	binds and unfolds substrates as part of the ClpXP protease
YP_933575.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_933576.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_933577.1	Putative serine protein kinase. Homology to prkA of Bacillus subtilis of 32% (gnl|keqq|bsu:BG10804 ). Pfam: PrkA serine kinase. This is a family of PrkA bacterial and archaeal serine kinases approximately 630 residues long. PrkA possesses the A-motif of nucleotide-binding proteins and exhibits distant homology to eukaryotic protein kinases. Note that many family members are hypothetical. Interpro: IPR010650 PrkA serine kinase. No signal peptide. No TMHs.,; Family membership
YP_933578.1	Conserved hypothetical protein,[yeaH]54% identical (71% similarity )to SwissProt;P59349. Has PF04285(IPR006698), Protein of unknown function (DUF444);Bacterial protein of unknown function. One family member (Q97LI1) is predicted to contain a von Willebrand factor (vWF) type A domain (Smart:VWA). No Signal peptide or TMH present.
YP_933579.1	Putative cytoplasmic protein[ycgB],67% identical (79% similarity) SwissProt;P29013. TrEMBL;Q8XDL3(67% identical)TrEMBL;Q8ZP16. Has PF04293, SpoVR like protein;IPR007390; Family member P37875 is Bacillus subtilis stage V sporulation protein R,which is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR. No Signal peptide or TMH present.; Family membership
YP_933580.1	38% UPF0031.IPR004443; YjeF_Nterm. Pfam:PF01256; Carb_kinase; 1.PF03853; YjeF_N; 1. TIGRFAMs:TIGR00196; yjeF_cterm; 1.TIGR00197; yjeF_nterm; 1.; Specificity unclear
YP_933581.1	HD-domain containing protein,; Conserved hypothetical protein
YP_933582.1	Conserved hypothetical membrane protein. Homology to PA0239 pf P. aeruginosa of 41%. InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transport. Pfam: Integral membrane protein DUF6. 10 TMHs. no signal peptide; Conserved hypothetical protein
YP_933583.1	Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase). TIGRFAM: nadC: nicotinate-nucleotide pyrophosphorylase; High confidence in function and specificity
YP_933584.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_933585.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_933586.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
YP_933587.1	Conserved hypothetical protein. Homology to RS02847 of R.solanacearum of 49% (trembl:Q8XZS0). Has PF04635,Protein of unknown function, DUF598;IPR006729; This family contains several uncharacterised proteins. No signal peptide or TMH present.
YP_933588.1	Member of the Major Facilitator Superfamily (MFS). MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Hypothetical transport protein yjjL. InterPro: General substrate transporters 2A0104: phosphoglycerate transporter; Function unclear
YP_933589.1	Probable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership
YP_933590.1	Putative transcriptional activator protein,; Function unclear
YP_933591.1	In Pseudomonas putida strain GB-1, XcmX is involved in a novel Xcp-related system for the transport of manganese-oxidizing enzymes to the cell surface. Similar trembl|Q8KSG3 (33%). TMHMM reporting one TMH. SignalP reporting a signal peptid.; Function unclear
YP_933592.1	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide.; Conserved hypothetical protein
YP_933593.1	General secretion pathway protein G,; Specificity unclear
YP_933594.1	Protein D is involved in the type II general secretion pathway within Gram-negative bacteria, a signal sequence-dependent process responsible for protein export. The most probable location of protein D is the outer membrane. This suggests that protein D constitutes the apparatus of the accessory mechanism, and is thus involved in transporting exoproteins from the periplasm, across the outer membrane, to the extracellular environment. Similar to trembl|Q8XTG8 (39%). Pfam (PF00263): General (type II) secretion pathway (GSP) D protein Pfam (PF07660): Secretin and TonB N terminus short domain Pfam (PF03958): Bacterial type II/III secretion system short domain SignalP reporting Signal peptide.; Specificity unclear
YP_933595.1	Conserved hypothetical secreted protein. Homology to rs02976 of R. solanacearum of 35% (trembl|Q8XTG7(SRS)). No domains predicted. Signal peptide present. no TMHs; Conserved hypothetical protein
YP_933596.1	Conserved hypothetical membrane protein. Homology to ebA1234 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA1234(KEGG)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_933597.1	Conserved hypothetical protein. Homology to ebA1229 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA1229(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933598.1	Conserved hypothetical protein. Homology to ebD34 of Azoarcus sp. EbN1 of 33% (gnl|keqq|eba:ebD34(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933599.1	General secretion pathway protein E (Type II traffic warden ATPase) INVOLVED IN A GENERAL SECRETION PATHWAY (GSP) FOR THE EXPORT OF PROTEINS. Similar to sprot|PILF_NEIGO (33%) and trembl|Q82U87 (54%). InterPro (PF00437): Bacterial type II secretion system protein E InterPro (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear
YP_933600.1	General secretion pathway protein F,similar trembl|Q88HD6 (39%). The general (type II) secretion pathway (GSP) within Gram-negative bacteria is a signal sequence-dependent process responsible for protein export. The process has two stages: exoproteins are first translocated across the inner membrane by the general signal-dependent export pathway (GEP), and then across the outer membrane by a species-specific accessory mechanism. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial general secretion pathway protein F TMHMM reporting five TMH.; Specificity unclear
YP_933601.1	General secretion pathway GSPG-related transmembrane protein,; Specificity unclear
YP_933602.1	Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) (Slt70). Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity). flhB_rel: FlhB domain protein; Family membership
YP_933603.1	Conserved hypothetical secreted protein. Homology to xac2776 of X. axonopodis of 50% (trembl|Q8PIW9). Pfam: DUF839 This family consists of several bacterial proteins of unknown function. signal peptide. no TMHs; Conserved hypothetical protein
YP_933604.1	catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate
YP_933605.1	Hypothetical membrane protein. No homology with hits in the database. No domains predicted. Signal peptide present. TMHMM2 reporting 1 TMH present.
YP_933606.1	DnaK suppressor protein,; High confidence in function and specificity
YP_933607.1	Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase). Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3 to 5 direction. Involved in the RNA degradosome a multi-enzyme complex important in RNA processing and messenger RNA degradation.; High confidence in function and specificity
YP_933608.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_933609.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_933610.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_933611.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_933612.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_933613.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_933614.1	Conserved hypothetical protein; Family membership
YP_933615.1	Putative segregation and condensation protein B,; Conserved hypothetical protein
YP_933616.1	Hypothetical protein, 51% identity(64% similarity) to TrEMBL;Q8XWT4. Has PF02616, Uncharacterised ACR,COG1354;This entry describes proteins of unknown function. InterPro; IPR003768; Specificity unclear
YP_933617.1	Conserved hypothetical membrane protein. Homology to NE1726 of N.europaea of 61% (trembl:Q82TY8). InterPro: IPR008915; Peptidase_M50. Pfam: PF02163; Peptidase_M50. Non-secretory protein signal peptide probability: 0.235. TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein
YP_933618.1	InterPro: Sua5/YciO/YrdC/YwlC protein family TIGR00057: Sua5/YciO/YrdC/YwlC family p; High confidence in function and specificity
YP_933619.1	TREMBL:Q7VZ25: 48% identity; 57% similarity SWISSPROT:TRPH_HAEIN:Protein trpH (38% identity). InterPro:IPR003141; PHP_N.PHP domain C-terminal region. The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. This family is often associated with an N-terminal region Pfam: PF02231; PHP_N; SMART: SM00481; POLIIIAc; thiE: thiamine-phosphate pyrophosphoryl; High confidence in function and specificity
YP_933620.1	Probable Serine hydrolase-like protein (EC 3.1.-.-). TREMBL:Q8Y0A9: 49% identity, 63% similarity. Pfam: abhydrolase; thioesterase TIGRFAM: murB: UDP-N-acetylenolpyruvoylglucosamine No transmembrane helix (predicted by TMHMM); Function unclear
YP_933621.1	Hypothetical protein. Very bad homology with hits. Has No domains, repeats, motifs or features detected.
YP_933622.1	Conserved hypothetical protein. Very Bad homology with hits in the database. Has SMART;SM00438;IPR000967,Znf_NFX1;This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C, where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosophila shuttle craft protein, which plays an essential role during the late stages of embryonic neurogenesis; and a yeast hypothetical protein YNL023C.
YP_933623.1	probable piperideine-6-carboxylate dehydrogenase. Homology to pcd of F. lutescens of 53% (trembl|Q9F1U8) InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership
YP_933624.1	Hypothetical protein MG442 homolog (K05_orf271). TREMBL:Q7NR72: 48% identity, 66% similarity InterPro; IPR005289; GTP-bindding_dom. InterPro; IPR002917; MMR_HSR1. Pfam; PF01926; MMR_HSR1; thiE: thiamine-phosphate pyrophosphor NO signal peptide No transmembrane helices; Specificity unclear
YP_933625.1	Cold shock-like protein,; High confidence in function and specificity
YP_933626.1	Cold-shock DEAD-box protein A (ATP-dependent RNA helicase deaD). HAS A HELIX-DESTABILIZING ACTIVITY. PLAYS A KEY ROLE IN OPTIMAL CELL GROWTH AT LOW TEMPERATURE AND IS REQUIRED FOR NORMAL CELL DIVISION (BY SIMILARITY).; Family membership
YP_933627.1	Putative acyl-CoA thioesterase. Homology to tesA of E. coli of 32% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase GDSL-like motif signal peptide no TMH; Family membership
YP_933628.1	catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages
YP_933629.1	TREMBL:Q9HT60:67% identity, 80% similarity to putative hydrolase. Hypothetical protein yqjL. InterPro: Alpha/beta hydrolase fold Pfam: abhydrolase; thioesterase domain uppS: undecaprenyl diphosphate synthase; Specificity unclear
YP_933630.1	Putative cytoplasmic protein [yaeQ],49% identity (64% similarity) to TrEMBL;Q79ID7. TrEMBL;Q8FKZ7(57% identity) SwissProt;P52100. Has PF07152, YaeQ protein;This family consists of several hypothetical bacterial proteins of around 180 residues in length which are often known as YaeQ. YaeQ is homologous to RfaH, a specialised transcription elongation protein. YaeQ is known to compensate for loss of RfaH function. No Signal Peptide or TMH present.; High confidence in function and specificity
YP_933631.1	Conserved hypothetical protein. Homology to ebA6182 Azoarcus sp. EbN1 of 55% (gnl|keqq|eba:ebA6182(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_933632.1	GGDEF-domain containing protein,; Conserved hypothetical protein
YP_933633.1	Hypothetical protein, 32% identity to TrEMBL;Q6MXJ8. No Signal Peptide, features or Domains present.
YP_933634.1	Catalytic activity :-acyl-[acyl-carrier protein] + nad(+) = trans- 2,3-dehydroacyl-[acyl-carrier protein] + nadh. pathway:- fatty acid biosynthesis pathway; second reduction step. Entry name SWISSPROT:FABI_ECOLI InterPro IPR002198; ADH_short. Identities = 108/252 (42%) Pfam PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0; High confidence in function and specificity
YP_933635.1	Conserved hypothetical protein. Homology to Daro03002758 of Dechloromonas aromatica of 51% (gi|53730017|ref|ZP_00150562.2|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_933636.1	Conserved hypothetical ATPase. Homology to Daro03000733 of Dechloromonas aromatica of 64% (gi|41725756|ref|ZP_00152514.1|(NBCI ENTREZ)). Domain structure: 101 aa - 293 aa AAA-protein. InterPro: AAA-protein (ATPases associated with various cellular activities) (IPR003959); AAA ATPase superfamily (IPR003593). Pfam: ATPases associated with various cellular activities. no signal peptide. no TMHS; Conserved hypothetical protein
YP_933637.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_933638.1	Hypothetical protein, has no good homology over the entire length with hits in Database. TrEMBL Q9HT58 Hypothetical protein PA5515 [PA5515] [Pseudomonas aeruginosa. No Signal Peptide or TMH being reported as present.; Family membership
YP_933639.1	Probable low-affinity phosphate transporter protein.Involved in phosphate transport depending on the proton motive force. InterPro: Phosphate transporter family Similar to PitA a cation-phosphate transporter in E.coli. No signal peptide; High confidence in function and specificity
YP_933640.1	Hypothetical protein ypjD. TREMBL:Q7W7V7: 56% identity, 65% similarity SPROT:YPJD_BACSU:P42979: 27% identity, 49% similarity This group of prokaryotic proteins has no known function. It includes the uncharacterized protein MazG in Escherichia coli. InterPro:IPR004518; MazG. Pfam: PF03819 No transmembrane helices (TMHMM predicted); Specificity unclear
YP_933641.1	Conserved hypothetical protein. Homology to cv2345 of C. violaceum of 54% (trembl|Q7NVJ7). no domains predicted. no signal peptide. no TMHs.
YP_933642.1	Hypothetical protein PA3753. A variety of bacterial transferases contain a repeat structure composed of tandem repeats of a [LIV]-G-X(4) hexapeptide, which, in the tertiary structure of LpxA (UDP N-acetylglucosamine acyltransferase) [1], has been shown to form a left-handed parallel beta helix TREMBL:Q9A526: 55% identity; 75% similarity bacterial transferase family protein. Superfamily: ferripyochelin binding protein InterPro:IPR001451; Hexapep_transf.Bacterial transferase hexapeptide repeat Pfam:PF00132; Hexapep; presence of DUF99 domain. No signal peptide (Signal P) or transmembrane helices (TMHMM).; Specificity unclear
YP_933643.1	Conserved hypothetical secreted protein. Homology to CV3305 of C.violaceum of 37% (tremble:Q7NSW4). Has PF04402, Protein of unknown function (DUF541);IPR007497:Members of this family have so far been found in bacteria and mouse SwissProt or TrEMBL entries. However possible family members have also been identified in translated rat (Genbank:AW144450) and human (Genbank:AI478629) ESTs. A mouse family member has been named SIMPL (signalling molecule that associates with mouse pelle-like kinase). SIMPL appears to facilitate and/or regulate complex formation between IRAK/mPLK (IL-1 receptor-associated kinase) and IKK (inhibitor of kappa-B kinase) containing complexes, and thus regulate NF-kappa-B activity. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_933644.1	Conserved hypothetical secreted protein. Homology to ebD110 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD110(KEGG)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_933645.1	Conserved hypothetical secreted protein. Homology to CV2523 of Chromobacterium violaceum of 48% (trembl:Q7NV23). Pfam: NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins. Signal peptide. No TMHs; Conserved hypothetical protein
YP_933646.1	Hypothetical protein MK0525 (OrfX). trembl|Q9V230 (Q9V230) Inosine-5'-monophosphate dehydrogenase related; 34% identity, 55% similarity. InterPro: CBS domain (IPR005857, IPR004840) TIGRFAM: kpsF/GutQ family TMHMM predicted absence of transmembrane helices; Specificity unclear
YP_933647.1	Conserved hypothetical membrane protein. Homology to CV3460 of C. violaceum of 54% (trembl|Q7NSG6(SRS)). Pfam: Septum formation initiator DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_933648.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_933649.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_933650.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_933651.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide present. TMHMM2 reporting 3 TMH present.
YP_933652.1	L-sorbosone dehydrogenase. Converts L-sorbosone to 2-keto-l-gulonic acid (2kga). 63% Peptidase_M14.IPR000595; cNMP_binding. Signal peptide:present.; High confidence in function and specificity
YP_933653.1	AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase
YP_933654.1	Probable Hypothetical protein AQ_1494. TREMBL:Q7WIS5: 37% identity; 51% similarity. This family contains a wide variety of enzymes, principally thioesterases. This family includes 4HBT (EC: 3.1.2.23) which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3. This family includes various cytosolic long-chain acyl-CoA thioester hydrolases. Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. InterPro:IPR006683; Thioestr_supf. Pfam:PF03061; 4HBT InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site No transmembrane helices TIGR00051: conserved hypothetical protein; Family membership
YP_933655.1	Probable electron transfer flavoprotein-ubiquinone oxidoreductase. Homology to etfdh of H. sapiens of 57% (sprot|ETFD_HUMAN) Accepts electrons and reduces ubiquinone. Pfam: FAD_binding_3; ETF_QO no signal peptide no TMHs
YP_933656.1	Hypothetical secreted protein. Homology to GSU2347 of G. sulfurreducens of 26% (tremblnew|AAR35721(SRS)). Has PF04338;Protein of unknown function, DUF481; This family includes several proteins of uncharacterised function. Signal P reporting signal peptide present. NO TMH reported to be present.
YP_933657.1	Conserved hypothetical secreted protein. Homology to PP2380 of P. putida of 47% (trembl:Q88KB0). Has PF04314, Protein of unknown function (DUF461);Putative membrane or periplasmic protein. Signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_933658.1	Conserved hypothetical secreted protein. 33% similarity to TrEMBL Q8XQF8 PROBABLE SIGNAL PEPTIDE PROTEIN [RS05314] [Ralstonia solanacearum (Pseudomonas solanacearum)]. No domains predicted. Signal P reporting signal peptide present. No TMH reported being present.; Conserved hypothetical protein
YP_933659.1	Conserved hypothetical secreted protein. Homology to rsc1270 of R. solanacearum of 44% (trembl|Q8XQF7(SRS)). no domains predicted .signal peptide present. no TMHs; Conserved hypothetical protein
YP_933660.1	TonB-dependent outer membrane receptor involved in the first step of iron internalization and metabolism. A short conserved region so called the tonB-box is present in the sequence. This domain is involved in the interaction of the receptor with the TonB protein. Similar to a E. coli iron(III) dicitrate transport protein fecA precursor. InterPro: TonB-dependent receptor protein arcC: carbamate kinase; Function unclear
YP_933661.1	Conserved hypothetical secreted protein. Homology to BB1293 of Bordetella bronchiseptica of 38% (trembl:Q7WMU7). No domains predicted. Signal peptide. No TMHs
YP_933662.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_933663.1	Conserved hypothetical membrane protein. Homology to CV3583 of C. violaceum of 30% (trembl|Q7NS44(SRS)). Pfam: PAP2 superfamily no signal peptide 8 TMHs; Conserved hypothetical protein
YP_933664.1	Conserved hypothetical membrane protein. Homology to smc02385 of S. meliloti of 32% (trembl:Q92KI4). No domains predicted. Signal peptide. 6 TMHs; Conserved hypothetical protein
YP_933665.1	Glycosyltransferase,; Specificity unclear
YP_933666.1	Hypothetical protein AQ_1704.; Family membership
YP_933667.1	Conserved hypothetical membrane protein. Homology to Daro03001595 of Dechloromonas aromatica of 38% (gi|53730877|ref|ZP_00348993.1|(NBCI ENTREZ)). InterPro IPR008934; AcPase_VanPerase. IPR000326; PA_PTPase. Pfam PF01569; PAP2; 1. Number of predicted TMHs: 6 Prediction: Non-secretory protein Signal peptide probability: 0.023; Conserved hypothetical protein
YP_933668.1	Function unclear
YP_933669.1	Conserved hypothetical secreted protein. Homology to ebA6137 of Azoarcus sp. EbN1 of 34% (gnl|keqq|eba:ebA6137(KEGG)). No domains predicted. Signal peptide present. No TMHs Coiled Coil present.; Conserved hypothetical protein
YP_933670.1	InterPro: Peptidase family M23/M37; Specificity unclear
YP_933671.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_933672.1	Conserved hypothetical protein. Homolog to RSC1420 of Ralstonia solanacearum of 63% (trembl:Q8XZH5). Has PF03618, Domain of unknown function (DUF299); IPR005177 ; Family of bacterial proteins with no known function. No signal peptide. No TMHs.
YP_933673.1	Conserved hypothetical secreted protein. Homology to BPP2392 of B.parapertussis of 42% (trembl:Q7W7W7). Signal P reporting signal peptide present. No TMH present. No domains predicted; Family membership
YP_933674.1	Conserved hypothetical peptide methionine sulfoxide reductase. Homology to msrB of S. elongatus of 64%. Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, Met(O), to methionine. InterPro: Domain of unknown function DUF25 (IPR002579). Pfam: Domain of unknown function DUF25. Tigrfam: TIGR00357: PilB-related protein. no TMHs; Family membership
YP_933675.1	The Trg transducer mediates chemotactic response to galactose and ribose by interacting, respectively, with sugar-occupied galactose- and ribose-binding proteins. Adaptation is linked to methylation of specific glutamyl residues of the Trg protein. Similar to sprot|MCP3_ECOLI (27%)and to TREMBL:Q88AC6. InterPro (IPR004089): Bacterial chemotaxis sensory transducer InterPro (IPR003660): HAMP InterPro (IPR004090): Methyl-accepting chemotaxis protein Pfam (PF00672): HAMP Pfam (PF00015): Methyl-accepting chemotaxis protein (MCP) signaling domain Pfam (PF05227): CHASE3 domain TMHMM reporting two TMH.; Specificity unclear
YP_933676.1	catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA
YP_933677.1	catalyzes the formation of adenosylcobinamide-phosphate from adenosylcobyric acid
YP_933678.1	Region start changed from 2383430 to 2383313 (-117 bases)
YP_933679.1	PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. Similar to trembl|Q8XW00 (31%). Pfam (PF01839): FG-GAP repeat SignalP reporting Signal peptide; Function unclear
YP_933680.1	Hypothetical secreted protein. Homology to RS00045 of R. solanacearum of 25% (trembl|Q8XVZ9(SRS)) No domains predicted Sinal P reporting singal peptide present. No TMH being reported.
YP_933681.1	In Pseudomonas aeruginosa, the PilW and PilX proteins are membrane located, possess the hydrophobic N-terminus characteristic of prepilin-like proteins, and appear to belong to the GspJ and GspK group of proteins that are required for protein secretion in a wide range of Gram-negative bacteria. These findings increase the similarities between the fimbrial biogenesis and the Gsp-based protein-secretion supersystems. Similar to trembl|Q8XVZ8 (29%). Smart (SM00438): Repressor of transcription TMHMM reporting one TMH. SignalP reporting Signal peptide.; Function unclear
YP_933682.1	Family membership
YP_933683.1	Probable type-4 fimbrial pilin related signal peptide protein,32% Identity to TrEMBL;Q8XVZ6,Q7NTE6. Has Signal peptide. Has COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].
YP_933684.1	In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similarity to PilE of Ralstonia eutropha (33%) TMHMM reporting one TMhelix. Pfam: pilin domain; Conserved hypothetical protein
YP_933685.1	Conserved hypothetical secreted protein. Homology to pa4048 of P. aeruginosa of 33% (trembl|Q9HWY0). no domains. signal peptide. no TMHs.; Conserved hypothetical protein
YP_933686.1	Conserved hypothetical protein. Homology to ebA5103 of Azoarcus sp. EbN1 of 57% (gnl|keqq|eba:ebA5103(KEGG)). no domains predicted. no signal peptide. no TMHs.
YP_933687.1	putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
YP_933688.1	Hypothetical protein,64% identical to TrEMBL;Q8XWC2 Has PF06865, Protein of unknown function (DUF1255);IPR009664 :This family consists of several conserved hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown. No Signal peptide or TMH not present.; High confidence in function and specificity
YP_933689.1	Conserved hypothetical membrane protein. Homology to NMA1807 of Neisseria meningitidis of 41% (trembl|Q9JTE8(SRS)). No domains predicted. TMHMM reporting 2 TMH present. NO Signal Peptide being reported present.; Conserved hypothetical protein
YP_933690.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_933691.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
YP_933692.1	catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine
YP_933693.1	Conserved hypothetical protein. Homology to bpp2544 of P. pararpertussis of 51% (TREMBL:Q7W7H5). no signal peptide. no TMHs. No domains predicted.
YP_933694.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_933695.1	TREMBL:Q82SD5:58% identity, 69% similarity The sequencing of a number of pathogenic bacterial genomes has led to novel virulence proteins being discovered that are yet to be biochemically characterised. One example is the MviN family of proteins, first described in Salmonella [1], and conserved across a wide variety of pathogens in both animals and plants. Further work on these proteins of as yet unknown function has revealed they are integral membrane molecules, and are part of an operon essential in at least one species subcellular location:integral membrane protein (potential). similarity:belongs to the mvin family Virulence factor mviN. InterPro:IPR004268; MVIN_like. Pfam:PF03023; MVIN (Virulence factor MVIN) InterPro: Virulence factor MVIN-like TMHMM predicted 13 transmembrane helices matE: MATE efflux family protein; High confidence in function and specificity
YP_933696.1	Hypothetical protein, has very bad homology with hits in the database. TrEMBL;Q762H6. Has Signal Peptide.
YP_933697.1	Probable O-acetylhomoserine aminocarboxypropyltransferase. Homology to cysD of A. nidulans of 51% (sprot|CYSD_EMENI). Transforms O-acetylhomoserine into homocysteine. Pfam: Cys/Met metabolism PLP-dependent enzyme no signal peptide no TMHs; High confidence in function and specificity
YP_933698.1	Conserved hypothetical membrane protein. Homology to rs04519 of R. solanacearum of 33% (trembl|Q8Y0Z7(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein
YP_933699.1	Hypothetical protein yhiN. FAD flavoproteins belong to the family of pyridine nucleotide-disulphide oxidoreductases TREMBL:Q7MBF1: 58% identity, 69% similarity InterPro: IPR001327; FAD_pyr_redox. IPR004792; HI0933_like. IPR000205; NAD_BS. IPR001100; Pyr_redox InterPro: HI0933-like protein Pfam:PF03486; HI0933_like; 1. TIGR00275: conserved hypothetical pro Non-secretory protein with signal peptide probability of 0.464 Absence of transmembrane helices (TMHMM predicted); Specificity unclear
YP_933700.1	Metallo-phosphoesterase, 50% identity(67% similarity) to TrEMBL;Q6N2S9 . TrEMBL;Q885N2(53% identity). Has PF00149, Calcineurin-like phosphoesterase;IPR004843,M-pesterase:This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD P13457 or yeast MRE11 P32829. The most conserved regions in this superfamily centre around the metal chelating residues. The metallo-phosphoesterase motif is found in a large number of proteins invoved in phosphoryation. These include serine/threonine phosphatases, DNA polymerase,exonucleases, and other phosphatases. No Signal Peptide or TMH present.; Specificity unclear
YP_933701.1	Putative bacterioferritin comigratory protein. Homology to bcp of E. coli of 37% (sprot|BCP_ECOLI) InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (IPR000866) Pfam: AhpC/TSA family no signal peptide no TMHs; Family membership
YP_933702.1	Putative PhoH-related protein,; Conserved hypothetical protein
YP_933703.1	Probable aerotaxis receptor protein,; High confidence in function and specificity
YP_933704.1	HD-domain containing protein,; Conserved hypothetical protein
YP_933705.1	Putative nucleotidyltransferase,; Conserved hypothetical protein
YP_933706.1	Probable DNA polymerase III, epsilon subunit,23% Identity to TrEMBL;Q8KDK8. Has EXOIII,SMART;SM00479;IPR006054, DnaQ;This family includes a variety of exonucleases, such as ribonuclease T and the epsilon subunit of DNA polymerase III. Ribonuclease T is responsible for the end-turnover of tRNA,and removes the terminal AMP residue from uncharged tRNA. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria, and also exhibits 3' to 5' exonuclease activity.
YP_933707.1	InterPro: NLP/P60; Family membership
YP_933708.1	Conserved hypothetical protein. Homology to CV2970 of C.violaceum of 42% (trembl:Q7NTT3). No domains predicted. No TMHs. No signal peptide.; Function unclear
YP_933709.1	Iron (III)-transport system, substrate-binding protein FbpA. Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import.Iron(III)periplasmic binding protein component.; High confidence in function and specificity
YP_933710.1	Iron(III)-transport system permease fbpB 2. Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import. Probably responsible for the translocation of the substrate across the membrane (By similarity). pts-Glc: PTS system maltose and gluco; High confidence in function and specificity
YP_933711.1	Ferric cations import ATP-binding protein fbpC 2 (EC 3.6.3.30). Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import. Responsible for energy coupling to the transport system (By similarity). InterPro: AAA ATPase superfamily apsK: adenylylsulfate kinase; Specificity unclear
YP_933712.1	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys
YP_933713.1	Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate
YP_933714.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_933715.1	Xanthine dehydrogenase (subunit A) oxidoreductase protein; High confidence in function and specificity
YP_933716.1	Xanthine dehydrogenase (subunit B) InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus; High confidence in function and specificity
YP_933717.1	xanthine dehydrogenase, probable (chaperone); High confidence in function and specificity
YP_933718.1	Conserved hypothetical sugar transporter ATP-binding protein. Homology to orf96 of P. sp strain ADP of 65% (TREMBL:Q936X7). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR sugars. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: AAA-ATPase; ABC transporter. no signal peptide. no TMHs; Specificity unclear
YP_933719.1	Conserved hypothetical ABC transporter permease. Homology to orf95 of Pseudomonas sp strain ADP of 57% (trembl|Q936X8). Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851). Pfam: Branched-chain ammino acid transporter/permease component. no signal peptide. 9 TMHs; Specificity unclear
YP_933720.1	TREMBL:Q8XXD9: 46% identity, 59% similarity Hypothetical protein MG120 homolog (A65_orf517). Bacterial inner-membrane translocator.The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown [3, 4] that most of these proteins contain a conserved region located about 80 to 100 residues from their C-terminal extremity InterPro:IPR001851; Bac_inmem_transp. Pfam:PF02653; BPD_transp_2 gntP: gluconate transporter TMH's 9 (TMHMM predicted); Specificity unclear
YP_933721.1	Similar to FecA, ferric-citrate outer membrane receptor in E.coli, involved in the recognition and internalization of ferric-citrate. InterPro: TonB-dependent receptor protein; Function unclear
YP_933722.1	Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the putative periplasmic-binding protein CbiK precursor in A.pleuropneumoniae. thiE: thiamine-phosphate pyrophosphoryla; High confidence in function and specificity
YP_933723.1	Conserved hypothetical membrane protein. Homology to cbiL of Actinobacillus pleuropneumoniae of 39% (gi|5733705|gb|AAD49725.1|(NBCI ENTREZ)). Signal P reproting signal peptide present. TMHMM reporting TMH present.; Conserved hypothetical protein
YP_933724.1	catalyzes the ATP-dependent transport of cobalt
YP_933725.1	Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae.; Function unclear
YP_933726.1	Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1.; High confidence in function and specificity
YP_933727.1	Catalyzes the deamination of guanine
YP_933728.1	Hypothetical protein yaiI,58% identical (75% similar) to SwissProt; P52088, of E.coli.SwissProt;Q8XEM1(61% identity) TrEMBL; Q8ED72. Has PF02639, Uncharacterized BCR, YaiI/YqxD family COG1671;IPR003791. No Signal peptide or TMH present.
YP_933729.1	GGDEF/EAL/PAS-domain containing protein
YP_933730.1	Probable N-acetylmuramoyl-L-alanine amidase amiA precursor, 28% identity to TrEMBL;Q823N1. 26% identity to SwissProt;P36548 Has SMART;SM00646, Ami_3. Signal Peptide present. Has PF01520; N-acetylmuramoyl-L-alanine amidase ;IPR002508 Amidase_3_hydro; This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls.
YP_933731.1	GGDEF/EAL/PAS-domain containing protein
YP_933732.1	Conserved hypothetical amino acid-binding protein. Homology to bb2160 of B. bronchiseptica of 39% (trembl|Q7WKE7). PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR AN AMINO ACID. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001311). Pfam: Bacterial extracellular solute-binding protein. Signal peptide. no TMHs; Family membership
YP_933733.1	Conserved hypothetical secreted protein. Homology to PSPTO5169 of P.syringae 45% (tremble:Q87UX3). No domains predicted. Signal P reporting Signal Peptide present. No TMH being reported as present.; Conserved hypothetical protein
YP_933734.1	Conserved hypothetical membrane protein. Homology to pp2721 of P. putida of 56% (trembl|Q88JC8(SRS). no domains predicted. no signal peptide. 3 TMHs; Conserved hypothetical protein
YP_933735.1	Mannose-1-phosphate guanyltransferase involved in the reaction:GTP + alpha-D-mannose 1-phosphate = diphosphate + GDPmannose. 51% Hexapep_transf.IPR005835; NTP_transferase. Pfam:PF00132; Hexapep; 2.PF00483; NTP_transferase; 1.; High confidence in function and specificity
YP_933736.1	61% UDPG_MGDP_dh. Pfam:PF00984; UDPG_MGDP_dh; 1.PF03720; UDPG_MGDP_dh_C; 1.PF03721; UDPG_MGDP_dh_N; 1. Signal peptide: present.; High confidence in function and specificity
YP_933737.1	60% WecB_TagA_CpsF. Pfam:PF03808; Glyco_tran_WecB; 1. TIGRFAMs:TIGR00696; wecB_tagA_cpsF; 1. Non-secretory protein.; High confidence in function and specificity
YP_933738.1	25% Polysacc_synt. Pfam:PF01943; Polysacc_synt; 1. TMhelix:14. Non-secretory protein.; Family membership
YP_933739.1	64%; High confidence in function and specificity
YP_933740.1	41% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1. Signal peptide: present.; High confidence in function and specificity
YP_933741.1	60% Glyco_trans_1. Pfam:PF00534; Glycos_transf_1; 1.; Specificity unclear
YP_933742.1	26%; Family membership
YP_933743.1	44% Acyl_transf_3. Pfam:PF01757; Acyl_transf_3; 1. TMhelix:9. Non-secretory protein.; High confidence in function and specificity
YP_933744.1	Tyrosine-protein kinase wzc (EC 2.7.10.1). Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). gidA: glucose-inhibited division prot; High confidence in function and specificity
YP_933745.1	21% LPS_Wzz_MPA. Pfam:PF02706; Wzz; 1. TMhelix:1. Signal peptide:present.; High confidence in function and specificity
YP_933746.1	Putative capsule polysaccharide export protein precursor.May be involved in polysaccharide polymerization or transport. 36% Poly_export. Pfam:PF02563; Poly_export; 1. Signal peptide: present.; Family membership
YP_933747.1	Conserved hypothetical secreted protein. Homology to TdenA01000001 of Thiobacillus denitrificans of 33% (gi|52007706|ref|ZP_00335083.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_933748.1	Hypothetical secreted protein. No homology to the data bank. No domains pedicted. No TMHs signal peptide
YP_933749.1	Hypothetical secreted protein. No good homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_933750.1	43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5.; Specificity unclear
YP_933751.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs
YP_933752.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_933753.1	Region start changed from 2464498 to 2464507 (-9 bases)
YP_933754.1	probable succinate semialdehyde dehydrogenase [NAD(P)+). Homology to thmS of Pseudonocardia sp. K1 of 55% (trembl|Q9F3V7). Is capable of oxidizing substrates using NADP as cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership
YP_933755.1	Hypothetical protein, 30% identiy(50% similarity) to TrEMBL;Q8FYJ1. TrEMBL;Q8YJA6. Has (IPR010755)PF07049,Protein of unknown function (DUF1332);This family consists of several hypothetical bacterial proteins of around 165 residues in length. The function of this family is unknown. No Signal peptide or TMH present.; Function unclear
YP_933756.1	Conserved hypothetical BNR domain protein. Homology to pa3080 of P. aeruginosa of 38% (trembl|Q9HZC8). InterPro: BNR repeat (IPR002860). Pfam: BNR repeat. BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide. no TMHs; Function unclear
YP_933757.1	Putative membrane protein MJ1562. TREMBL:Q88J37: 52% identity, 66% similarity InterPro:IPR001036; Acrflvin_res. IPR000731; SSD_5TM Pfam:Patched:Patched family 2A067: efflux transporter putative Presence of signal peptide (Signal P predicted). Transmembrane helices 12 (TMHMM predicted); Family membership
YP_933758.1	Conserved hypothetical secreted protein. Homology to PP2811 of P.putida of 32% (tremble:Q88J38). Has PF06980;Protein of unknown function (DUF1302)domain;IPR010727 This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. Signal peptide present. No TMH reported.; Conserved hypothetical protein
YP_933759.1	Conserved hypothetical secreted protein. Homology to PA3081 of P.aeruginosa of 43% (trembl:Q9HZC7). Has pfam07044, DUF1329, Protein of unknown function (DUF1329). IPR010752; This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. Signal Peptide present. No TMH being reported.; Conserved hypothetical protein
YP_933760.1	Conserved hypothetical cytochrome c-552. Homology to Bcepa03004834 of Burkholderia cepacia of 38% (gi|46313246|ref|ZP_00213837.1|(NBCI ENTREZ)). InterPro: Cytochrome c class I (IPR003088). Pfam: cytochrome c. probable signal peptide. no TMHS; Conserved hypothetical protein
YP_933761.1	Probable methylamine dehydrogenase. Homology to mauD of P. denifrificans of 45% (CAA67190) carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. InterPro: Methylamine dehydrogenase L subunit (IPR004229) Pfam: Methylamine dehydrogenase, L chain signal peptide no TMHs; High confidence in function and specificity
YP_933762.1	Probable methylamine utilization protein. My be specifically involved in the processing transport and/or maturation of the methylamine dehydrogenase beta-subunit. Tigrfam: dsbE: periplasmic protein thiol:disulfide Signal peptide probable 1 TMHs; Family membership
YP_933763.1	Methylamine utilization protein mauE. Homology to mauE of M. extorquens of 37% (sprot|MAUE_METEX) MAY BE SPECIFICALLY INVOLVED IN THE PROCESSING TRANSPORT AND/OR MATURATION OF THE MADH BETA-SUBUNIT. no signal peptide probable 4 TMHs; Family membership
YP_933764.1	Methylamine dehydrogenase heavy chain precursor (MADH):- Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Entry name SWISSPROT:DHMH_METEX Prim. accession # Q49124 Identities = 100/339 (29%) Prediction: Signal peptide Signal peptide probability: 1.000 Number of predicted TMHs: 0; Family membership
YP_933765.1	Putative ethanolamine operon transcriptional regulator,; Family membership
YP_933766.1	Putative pyruvate dehydrogenase complex repressor,; Family membership
YP_933767.1	Putative amino acid-binding protein. Homology to fliy of E. coli of 26% (AAC43545). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR amino acids. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR1638); solute binding protein/glutamte receptor (IPR001311) Pfam: Bacterial extracellular solute-binding protein signal peptide no TMHS hisG: ATP phosphoribosyltransferase; Specificity unclear
YP_933768.1	Amino acid ABC transporter permease, 75% Identity to TrEMBL;Q87UQ0, 65% Identity to TrEMBL;Q8XXK9,Q6F6T8. Has PF00528; IPR000515, BPD_transp; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown that most of these proteins contain a conserved region located about 80 to 100 residues from their C-terminal extremity. This region seems to be located in a cytoplasmic loop between two transmembrane domains. Apart from the conserved region,the sequence of these proteins is quite divergent, and they have a variable number of transmembrane helices,however they can be classified into seven families which have been respectively termed: araH, cysTW, fecCD, hisMQ,livHM, malFG and oppBC. Has PROSITE;PS50928; ABC_TM1
YP_933769.1	Conserved hypothetical amino acid permease. Homology to pspto5247 of P. syringae (trembl|Q87UP9). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE (BY SIMILARITY). Interpro: binding-protein-depenent transport system inner membrane component (IPR000515). Pfam: Binding-protein-dependent transport system. no signal peptide. 3 TMHs; Specificity unclear
YP_933770.1	Probable glutamine transport ATP-binding protein. Homology with glnQ of B. stearothermophilus of 53% (sprot|GLNQ_BACST). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. InterPro: AAA ATPase superfamily (IPR003593), ABC_Transporter (IPR003439), ATP/GTP_binding site motif A (P-loop) (IPR001687) Pfam: ABC transporter no signal peptide no TMHs mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity
YP_933771.1	Probable Glutathione transferase. Homology to gstB of P. mirablilis of 29% (sprot|GT_PROMI). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. InterPro: Glutathione S-transferase N terminus(IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminale domaine no signal peptide no TMHs; Family membership
YP_933772.1	Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein
YP_933773.1	Conserved hypothetical band 7 family protein. Homology to pp4834 of P.putida of 67% (trembl|Q88DJ1). InterPro: Band 7 protein (IPR001107). Pfam: SPFH domain / Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family. These include the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. Bacterial HflC protein also belongs to this family. probable 1 TMH. probable signal peptide (overlapping with the TMH); Family membership
YP_933774.1	Methyl-accepting chemotaxis transducer,; Specificity unclear
YP_933775.1	Conserved hypothetical protein. Homology to Daro03003250 of Dechloromonas aromatica of 32% (gi|41723264|ref|ZP_00150207.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_933776.1	Low affinity potassium transport system protein,Kup. In E.coli, Kup has two domains, the first aa residues form an integral membrane domain and the C-terminal residues form a hydrophilic ones located at the citoplasmic side of the membrane. Kup: involved in potassium uptake and metabolism.; High confidence in function and specificity
YP_933777.1	Conserved hypothetical protein:- Entry name:-TREMBL:Q89MA9 Prim. accession # Q89MA9 InterPro:-IPR000379; Ser_estrs. Identities = 120/294 (40%) Pfam:-Thioesterase domain Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0
YP_933778.1	Sulfate-binding protein precursor, Sbp. E.coli Sulfate starvation-induced protein 2,SSI2. This protein specifically binds sulfate and is involved in its transmembrane transport. InterPro: Prokaryotic sulfate- /thiosulfate-binding protein. In other bacteria Sbp is a periplasmic component of an ABC transport system. TIGR00363: lipoprotein YaeC family Signal peptide; High confidence in function and specificity
YP_933779.1	Hypothetical protein ycjL. TREMBL:Q890B8: 38% identity, 53% similarity. Glutamine amidotransferase activity involves the removal of the ammonia group from a glutamate molecule and its subsequent transfer to a pecific substrate, thus creating a new carbon-nitrogen group on the substrate. InterPro:IPR000991; GATase_1 PROSITE PS00442 GATASE_TYPE_I BLOCKS: BL00442 PFAM:PF00117 GATase; PF00310 GATase_2 trpG_papA: glutamine amidotransferase o No signal peptide (SignalP predicted) No transmembrane helices; High confidence in function and specificity
YP_933780.1	ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity
YP_933781.1	Conserved hypothetical Na/H antiporter. Homology to Bucepa03004091 of B.cepacia of 41% (gi|46320868|ref|ZP_00221251.1|(NBCI ENTREZ)). Has PF00999 Sodium/hydrogen exchanger family; IPR006153. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family. No signal peptide. 12 TMHs.; Conserved hypothetical protein
YP_933782.1	Conserved hypothetical protein. Homology to pa3943 of P. aeruginosa (TREMBL:Q9HX73). no domians predicted. weak evidence for signal peptide. no TMHs
YP_933783.1	Conserved hypothetical protein. Homology to Avin02000067 of Azotobacter vinelandii of 50% (gi|23105742|ref|ZP_00092196.1|(NBCI ENTREZ)). InterPro: Ankyrin-repeat. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids.The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure. No signal peptide. No TMHs.
YP_933784.1	Hypothetical protein 25% Identity to TrEMBL;Q7U749. No domains, repeats, motifs or features present
YP_933785.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_933786.1	Conserved hypothetical protein. Identity to Daro_1071 of Dechloromonas aromatica of 41% (gi|71846331|gb|AAZ45827.1|). Pfam: CheW-like domain. CheW-like domain proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.
YP_933787.1	Similar to TREMBL:Q92PT6 (40% identical); TREMBL:Q98MM5 (39% identical).
YP_933788.1	Similar to TREMBL:Q9RBR1 (43% identity); TREMBL:Q8GN85 (42% identity); TREMBL:Q87NF7 (23% identity). SignalP predicting signal peptide.; Specificity unclear
YP_933789.1	The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 38% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. Signal peptide:present. TMhelix:11.; Specificity unclear
YP_933790.1	TRAP-type C4-dicarboxylate transport system, small permease component. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate.40% DctQ. Pfam:PF04290; DctQ; 1. TMHelix:3.; Function unclear
YP_933791.1	Conserved hypothetical protein. Homology to tll1086 of T.elongatus of 62% (trembl:Q8DJY4). No domains predicted. No TMHs. No signal peptide.
YP_933792.1	HD-domain containing protein,; Conserved hypothetical protein
YP_933793.1	Mg(2+) transport ATPase [mgtC family protein], 35% identity(54% similarity) to TrEMBL;Q7NTN3. Has PF02308,MgtC family;(IPR003416, MgtCSapB_transpt);The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known, but it is thought that MgtC may act as an accessory protein for MgtB, thus mediating magnesium influx into the cytosol. Also included in this family are the Bacillus subtilis SapB protein and several hypothetical proteins. NO Signal Peptide or TMH present.; Family membership
YP_933794.1	Conserved hypothetical protein. Homology to hypothetical protein all0327 of Anabaena sp. of 52%. no signal peptid. no TMHs. No domains predicted.
YP_933795.1	Conserved hypothetical DNA transformation protein,; Conserved hypothetical protein
YP_933796.1	Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity
YP_933797.1	Alkylated DNA repair protein.Probably involved in the repair of alkylated DNA. Provides extensive resistance to alkylating agents.; High confidence in function and specificity
YP_933798.1	Putative Zinc carboxypeptidase-related protein, 45% identity to TrEMBL;Q6MKH4,Zinc carboxypeptidase-related protein (EC 3.4.17.-) [Bd2418] [Bdellovibrio bacteriovorus] Has pfam00246, Zn_carbOpept, Zinc carboxypeptidase domain.; High confidence in function and specificity
YP_933799.1	TREMBL:Q8EFJ6: 33% identity, 47% similarity. Probable Dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) (Acetoin dehydrogenase E2 component). Interpro:IPR000073; A/b_hydrolase (alpha/beta fold family). IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 2a75: L-lysine exporter; Function unclear
YP_933800.1	PHS (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD). InterPro: Pterin 4 alpha carbinolamine dehydratase; High confidence in function and specificity
YP_933801.1	Conserved hypothetical protein. Homology to RS05664 of R.solanacearum of 53% (trembl:Q8XQC7). No domains predicted. No signal peptide or TMH reported present.
YP_933802.1	Conserved hypothetical protein. Homology to PA1356 of Pseudomonas aeruginosa of 69% (trembl|Q9I3Y8(SRS)). No domains predicted. No signal peptide or TMH reported to be present.
YP_933803.1	Aidb protein:-belongs to the acyl-coa dehydrogenase family. Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name SWISSPROT:AIDB_ECOLI Prim. accession # P33224 Identities = 257/515 (49%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1 Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_933804.1	Conserved hypothetical membrane protein. Homology to ORF428 of Roseateles depolymerans of 65% (trembl|Q9F206(SRS)). Pfam: Protein of unknown function (DUF1504). This family consists of several hypothetical bacterial proteins of around 440 residues in length. The function of this family is unknown. signal peptide. 10 TMHs; Conserved hypothetical protein
YP_933805.1	General secretion pathway protein E,; Specificity unclear
YP_933806.1	Conserved hypothetical protein. Homology to Mll6421 of M.loti of 37% (trembl:Q989H3). Has PF02661, Fic protein family;IPR003812:This family consists of the Fic (filamentation induced by cAMP) protein and its relatives. The Fic protein is involved in cell division and is suggested to be involved in the synthesis of PAB or folate, indicating that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism. This family contains a central conserved motif HPFXXGNG in most members. The exact molecular function of these proteins is uncertain. No signal peptide or TMH present.
YP_933807.1	Conserved hypothetical membrane protein. Homology to Daro03002720 of Dechloromonas aromatica of 55% (gi|41723618|ref|ZP_00150528.1|(NBCI ENTREZ)). Permease,member of the Major Facilitator Superfamiliy (MFS)transporters.MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Similar to proteins involved in tetracycline resistance. Hypothetical transport protein yhcA, from B.subtilis. InterPro: Drug resistance transporter EmrB/QacA subfamily efflux_EmrB: drug resistance transport. Signal peptide predicted. 13 TMHs; Function unclear
YP_933808.1	Transcriptional regulator, MerR-family InterPro: Bacterial regulatory protein, MerR, Putative DNA binding HTH reporting nucleic acid binding motif
YP_933809.1	Conserved hypothetical protein. Homology to CV1954 of Chromobacterium violaceum of 33% (trembl:Q7NWM9). No domains predicted. No TMHs. No signal peptide.
YP_933810.1	Tyrosine recombinase xerD. Site-specific tyrosine recombinase which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region forming the heterotetrameric xerC-xerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex xerD specifically exchanges the bottom DNA strands (By similarity). InterPro: Phage integrase; Specificity unclear
YP_933811.1	Hypothetical protein, 39% similarity to TrEMBL;Q8Z0Z1. No Signal Peptide or TMH present. TIGR00090: iojap-related protein
YP_933812.1	Hypothetical protein yjiV. TREMBL:Q8XC75: 33% identity, 49% similarity InterPro: IPR001410;DEAD/DEAH box helicase IPR001650; Helicase_C. Pfam: PF00270; DEAD; 1. PF00271; Helicase_C; 1. SMART: SM00487; DEXDc; 1. SM00490; HELICc L18_bact: ribosomal protein L18 No signal peptide No transmembrane helices; High confidence in function and specificity
YP_933813.1	Conserved hypothetical protein. 61% identity to hypothetical protein Bucepa02000624 [Burkholderia cepacia R1808] (gi|46324486|ref|ZP_00224847.1|(NBCI ENTREZ)). NO Signal peptide or TMH reported present. no domains predicted
YP_933814.1	Alpha -D-1,4-glucosidase, PalZ. Involved in the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. 55% Alpha_amyl_cat.IPR006589; Alp_amyl_cat_sub.IPR006046; Glyco_hydro_13. Pfam:PF00128; Alpha-amylase;1.; High confidence in function and specificity
YP_933815.1	Glucan 13-beta-glucosidase precursor (EC 3.2.1.58) (Exo-13-beta- glucanase).BETA-GLUCANASES PARTICIPATE IN THE METABOLISM OF BETA-GLUCAN THE MAIN STRUCTURAL COMPONENT OF THE CELL WALL. IT COULD ALSO FUNCTION BIOSYNTHETICALLY AS A TRANSGLYCOSYLASE. 33% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1.; High confidence in function and specificity
YP_933816.1	Conserved hypothetical membrane protein. Homology to Avin02002177 of Azotobacter vinelandii of 61% (gi|53611929|ref|ZP_00090985.2|(NBCI ENTREZ)). InterPro: ABC transporter (IPR003439). Pfam: ABC transporter. no signal peptide. 5 TMHs; Conserved hypothetical protein
YP_933817.1	Glucokinase (EC 2.7.1.2) (Glucose kinase). Catalytic activity: ATP + d-glucose = ADP+ d-glucose 6-phosphate. 24% Glucokinase. Pfam:PF02685; Glucokinase; 1. TIGRFAMs:TIGR00749; glk; 1.; High confidence in function and specificity
YP_933818.1	Family membership
YP_933819.1	Conserved hypothetical tyrosine/serine phosphatase,; Conserved hypothetical protein
YP_933820.1	Lipid A export ATP-binding/permease msbA. MsbA (TC 3.A.1.106.1) is involved in lipid A and possibly also glycerophospholipids export. The transmembrane domain (TMD) forms a pore in the inner membrane and the ATP-binding domain (NBD) is responible for energy generation. Similar to TREMBL:Q8ZGA9; TREMBL:Q8XXB6; SWISSPROT:P60752 (37% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. InterPro (IPR001140): ABC transporter transmembrane region. Pfam (PF00664): ABC transporter transmembrane region. Pfam (PF00005): ABC transporter. TMHMM reporting five transmembrane helices. TC (3.A.1.106): The Lipid Exporter (LipidE) Family.; High confidence in function and specificity
YP_933821.1	Hypothetical protein predicted by Glimmer/Critica. No homology of the entire protein to the data bank. no dmains predicted. no signal peptide. no TMHs
YP_933822.1	Hypothetical membrane protein. homology to rsc2204 of R.solanacearum of 28% (trembl|Q8XXB2(SRS)). no domains predicted. no signal peptide. 10 TMHs
YP_933823.1	CMP-N-acetylneuraminate-beta-galactosamide-alpha- 23- sialyltransferase (EC 2.4.99.4) (Beta-galactoside alpha-23-sialyltransferase) (Alpha 23-ST) (Gal-NAc6S) (Gal-beta-13-GalNAc-alpha-23-sialyltransferase) (ST3GalIA) (ST3O) (ST3GalA.1) (SIAT4-A) (ST3Gal I). IT MAY BE RESPONSIBLE FOR THE SYNTHESIS OF THE SEQUENCE NEUAC-ALPHA-23-GAL-BETA-13-GALNAC- FOUND ON SUGAR CHAINS O-LINKED TO THR OR SER AND ALSO AS A TERMINAL SEQUENCE ON CERTAIN GANGLIOSIDES. SIAT4-A AND SIAT4-B SIALYLATE THE SAME ACCEPTOR SUBSTRATES BUT EXHIBIT DIFFERENT KM VALUES.; Specificity unclear
YP_933824.1	Conserved hypothetical protein. Homology to Rsph03001342 of Rhodobacter sphaeroides of 39% (gi|22957735|ref|ZP_00005426.1|(NBCI ENTREZ)). Has PF04230, Polysaccharide pyruvyl transferase;IPR007345 PS_pyruv_trans; Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora. No signal peptide. No TMHs
YP_933825.1	High confidence in function and specificity
YP_933826.1	Hypothetical glycosyl transferase MJ1607 (EC 2.-.-.-). InterPro: Glycosyl transferases group 1; Specificity unclear
YP_933827.1	Lipopolysaccharide core biosynthesis glycosyl transferase lpsE (EC 2.-.-.-).; Specificity unclear
YP_933828.1	29% Polysac_deacet. Pfam:PF01522; Polysacc_deac_1; 1.; High confidence in function and specificity
YP_933829.1	Conserved hypothetical protein. Homology to CV1439 of Chromobacterium violaceum of 58% (trembl:Q7NY36). No domains predicted. No TMHs. No signal peptide.
YP_933830.1	Conserved hypothetical signaling protein,; Conserved hypothetical protein
YP_933831.1	HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 42% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity
YP_933832.1	Probable transcriptional regulator,; Specificity unclear
YP_933833.1	For the transport of bound iron across the inner membrane, a receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer membrane receptors. InterPro: Proline-rich region; Function unclear
YP_933834.1	Putative biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 36%. ExbB is part of the TonB-dependent transduction complex. The tonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family signal peptide most probable 4TMHs; Family membership
YP_933835.1	Putative biopolymer transport protein exbD. Homology to exbD of E. coli of 34%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership
YP_933836.1	Putative biopolymer transport protein. Homology to exbD1 of X. campestris of 31%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership
YP_933837.1	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q7WF48 (49% identity); TREMBL:Q881X8 (49% identity). Pfam (PF00529): HlyD family secretion protein. TMHMM reporting one transmembrane helix. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership
YP_933838.1	AcrB/AcrD/AcrF family protein. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer,SWISSPROT:P76399 (44% identity). Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM reporting 10 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; High confidence in function and specificity
YP_933839.1	AcrB/AcrD/AcrF family member. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q881X7 (44% identity); SWISSPROT:P76399 (48% identity). InterPro (IPR001036): Acriflavin resistance protein Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM reporting 10 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. HTH reporting nucleic acid binding motif.; Specificity unclear
YP_933840.1	Putative outer membrane efflux protein. Homology to opcM of B. cepacia of 36%. Component of an efflux system that confers multiple antibiotic resistence. Pfam: outer membrane efflux protein signal peptide no TMHs; Family membership
YP_933841.1	Conserved hypothetical hydrogenase cytochrone b-type subunit. Homology to C. vinosum of 48% (trembl|Q46471). Involved in electron transfer from hydrogen to oxygen. Pfam: Nickel-dependent hydrogenase b-type cytochrome. probable signal peptide. probable 4 TMHs; Family membership
YP_933842.1	Tail-specific protease precursor (EC 3.4.21.102) (Protease Re) (PRC protein) (C-terminal processing peptidase). prc: carboxyl-terminal protease; High confidence in function and specificity
YP_933843.1	Probable cytochrome c'. Homology to cycA of C. vinosum of 48% (sprot|CYCP_CHRVI). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN. InterPro: Cytochrome c class II (IPR002321) Pfam: Cytochrome c singal peptide no TMHs; Function unclear
YP_933844.1	Dienelactone hydrolases play a crucial role in chlorocatechol degradation via the modified ortho cleavage pathway, TREMBL:Q8XBV0 (48% identity); TREMBL:Q8EI44 (45% identity). InterPro (IPR002925): Dienelactone hydrolase. InterPro (IPR000379): Esterase/lipase/thioesterase. Pfam (PF01738): Dienelactone hydrolase family. SignalP predicting signal peptide.; Family membership
YP_933845.1	Gluconolactonase precursor (D-glucono-delta-lactone lactonohydrolase).HYDROLYZES THE GLUCONOLACTONE FORMED BY GLUCOSE-FRUCTOSE OXIDOREDUCTASE AND THAT FORMED IN AEROBIC CONDITIONS BY THE GLUCOSE DEHYDROGENASE PRESENT. 30% SMP-30. Pfam:PF03758; SMP-30; 1. Signal peptide: present.; High confidence in function and specificity
YP_933846.1	Putative cytochrome c4. Homology to cc4 of A. vinelandii of 34% (sprot|CYC4_AZOVI). Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems. Pfam: cytochrome C signal peptide no TMHs; Family membership
YP_933847.1	Conserved hypothetical bacterioferritin comigratory protein homolog. Homology to bp1307 of B. pertussis of 43% (trembl|Q7VYL2). Pfam: AhpC/TSA family. signal peptide. no TMHs; Family membership
YP_933848.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_933849.1	Conserved hypothetical secreted protein. Homology to RB5328 of Rhodopirellula baltica of 47% (trembl|Q7US09(SRS)). Signal Peptide present. No TMH reported Present. Has PF07394, Protein of unknown function (DUF1501);IPR010869;This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.; Conserved hypothetical protein
YP_933850.1	Conserved hypothetical secreted protein. Homology to RB6288 of Rhodopirellula baltica of 30% (trembl|Q7UQJ4(SRS)). No domains predicted. No TMHs. Signal P reporting signal peptide.; Conserved hypothetical protein
YP_933851.1	Yersinia enterocolitica,iron-repressible outer membrane protein, FyuA. FyuA:RECEPTOR FOR THE BACTERIOCIN PESTICIN AND FOR THE SIDEROPHORE YERSINIABACTIN. TonB-dependent outer membrane receptor.; Function unclear
YP_933852.1	Similar to a Rhodanese-related sulfurtransferase,PspE. , PspE:Thiosulphate sulphurtransferase ( 2.8.1.1) is an enzyme which catalyzes the transfer of the sulphane atom of thiosulphate to cyanide, to form sulphite and thiocyanate.Involved in cyanide detoxification., Signal peptide present.,; Function unclear
YP_933853.1	Conserved hypothetical membrane protein. Homology to PA0435 of Pseudomonas aeruginosa of 35% (trembl|Q9I682(SRS)). No domains predicted. Signal peptide. 3 TMHs; Conserved hypothetical protein
YP_933854.1	Conserved hypothetical protein. Homology to orf of Desulfovibrio vulgaris of 41% (tremblnew|AAS97780(SRS)). No domain predicted. No TMHs. No signal peptide.
YP_933855.1	Putative arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier),; Family membership
YP_933856.1	Putative regulatory protein arsR-family arsenical resistance operon repressor, smtB from Synechococcus PCC 7942, which acts as a transcriptional repressor of the smtA gene that codes for a metallothionein; cadC, a protein required for cadmium-resistance; and hypothetical protein yqcJ from Bacillus subtilis.; Family membership
YP_933857.1	Putative arsenate reductase,; Family membership
YP_933858.1	Putative arsenical-resistance protein arsB,; Family membership
YP_933859.1	Arsenical resistance operon trans-acting repressor ArsD,; Family membership
YP_933860.1	Arsenite-transporting ATPase,; High confidence in function and specificity
YP_933861.1	Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.-) (Glu-ADT subunit A). Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).; Family membership
YP_933862.1	Hypothetical AraC-family transcriptional regulator
YP_933863.1	oxaloacetate tautomerase,41% identity to TrEMBL;O32183;YusQ protein [yusQ] [Bacillus subtilis subsp. subtilis str. 168]. Has PF01361;(IPR004370);Tautomerase enzyme;This family includes the enzyme 4-oxalocrotonate tautomerase Q01468 that catalyses the ketonisation of 2-hydroxymuconate to 2-oxo-3-hexenedioate. No Signal peptide or TMH reported present.; Conserved hypothetical protein
YP_933864.1	Transcriptional regulator, LysR family,; Specificity unclear
YP_933865.1	Acetyl esterase:-has an esterase activity. triacetyl glycerol (triacetin) is a substrate of the enzyme. Entry name SWISSPROT:AES_ECOLI Prim. accession # P23872 Identities = 57/229 (24%) InterPro IPR002168; Lipolytic_enzyme. IPR000379; Ser_estrs. Pfam :-Thioesterase Prediction: Non-secretory protein Signal peptide probability: 0.233 Number of predicted TMHs: 0; Family membership
YP_933866.1	Putative sensor kinase/response regulator hybrid protein,; Specificity unclear
YP_933867.1	Sulfate-binding protein precursor, Sbp. 69% Sulphate_bind. IPR005669; Thiosulph_bind.InterPro: Prokaryotic sulfate-/thiosulfate-binding protein. TIGRFAMs:TIGR00971; 3a0106s03; 1. Belongs to the prokaryotic sulfate binding protein family. In other bacteria Sbp is a periplasmic component of an ABC transport system.; High confidence in function and specificity
YP_933868.1	Conserved hypothetical secreted protein. Homology to bll5801 of B. japonicum of 57% (trembl|Q89I38(SRS)). No domains predicted. Signal P reporting signal peptide present. No TMH present.; Conserved hypothetical protein
YP_933869.1	Chaperonin GroES. Homology to groES of B. japonicum of 58% (sprot|CH11_BRAJA). Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. InterPro: Chaperonins cpn10 (10 Kd subunit)(IPR001476) Pfam: chaperonin 10 Kd subunit no signal peptide no TMH; High confidence in function and specificity
YP_933870.1	Chaperonin GroEL. Homology to groEL of B. japonicum of 65% (SWISSPROT:CH61_BRAJA). Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity). Pfam: TCP-1/cpn60 chaperonin family no TMHs; High confidence in function and specificity
YP_933871.1	Transcriptional regulator, LysR family,; Function unclear
YP_933872.1	Conserved hypothetical protein. Homology to RSc3335 of Ralstonia solanacearum of 52% (gnl|keqq|rso:RS02569(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_933873.1	Conserved hypothetical membrane protein. Homology to Pflu02000368 of Pseudomonas fluorescens of 34% (gi|48732319|ref|ZP_00266062.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 4 TMHs; Conserved hypothetical protein
YP_933874.1	Hypothetical secreted protein. No domains predicted. No TMHs. Signal Peptide present. Weak homology with hits in the database.
YP_933875.1	30S ribosomal protein S4, truncated. Homology of aa 1 to 108 with rpsD of N. europaea of 67% (sprot|RS4B_NITEU(SRS)). With S5 and S12 plays an important role in translational accuracy (By similarity). Pfam: Ribosomal protein S4/S9 n-terminal domain. no signal peptide. no TMHs; Family membership
YP_933876.1	Hypothetical secreted protein. No homology with the data bank. No domains predicted. Signal peptide present. No TMHs
YP_933877.1	FecI: belongs to the extracytoplasmic-function (ECF) sigma factor, which represent a subgroup of the sigma 70 family. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Involved in iron metabolism.; High confidence in function and specificity
YP_933878.1	FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm. Involved in iron metabolism.; High confidence in function and specificity
YP_933879.1	Ferric-citrate outer membrane receptor,FecA.Involved in the recognition and internalization of ferric-citrate in E.coli. SPECIFIC RECEPTOR FOR THE SIDEROPHORE FERRIC PSEUDOBACTIN 358. InterPro: TonB-dependent receptor protein; High confidence in function and specificity
YP_933880.1	Conserved hypothetical membrane protein. Homology to NE0537 of Nitrosomonas europaea of 40% (trembl|Q82WX0(SRS)). no domains predicted. signal peptide. 3 TMHs; Conserved hypothetical protein
YP_933881.1	Similar to Rhodanese, a sulphurtransferase involved in cyanide detoxification. Non-secretory protein. Probable Hypothetical protein RP600.; Function unclear
YP_933882.1	Hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q87X35 Has PF04336, Protein of unknown function,DUF479;IPR007431,This family includes several bacterial proteins of uncharacterised function.; Function unclear
YP_933883.1	Hypothetical protein, 44% identity (54% similarity) to TrEMBL;Q82TM9. Has PF01636;Phosphotransferase enzyme family;IPR002575,APH_trans;This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include:-aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. Has PF03881,Fructosamine kinase;This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterised but probably have a similar or identical function.; Specificity unclear
YP_933884.1	Glycosyltransferase; Specificity unclear
YP_933885.1	Conserved hypothetical protein. Extremely weak homology with hits in the Database spanning the entire length of protein. Has PF02366, Dolichyl-phosphate-mannose-protein mannosyltransferase; IPR003342,Glyco_trans_39:This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferases. These proteins are responsible for O-linked glycosylation of proteins, they catalyse the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Q94891 Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to STT3. TMHMM2 reporting 2 TMH's present. Signal peptide not present.; Function unclear
YP_933886.1	Conserved hypothetical secreted protein. Homology to TdenA01002104 of Thiobacillus denitrificans of 56% (gi|52006510|ref|ZP_00333890.1|(NBCI ENTREZ)). No domains predicted. Signal P repoting a signal peptide present. NO TMH being present.; Conserved hypothetical protein
YP_933887.1	Conserved hypothetical protein. Homology to rsp0720 of R. solanacearum of 43% (trembl|Q8XRW1(SRS)). Pfam: FMN_binding domain. This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins. Siganl peptide. no TMHs
YP_933888.1	Conserved hypothetical ApbE family protein. Homology to so1090 of S. oneidensis of 43% (trembl|Q8EHX0). Pfam: ApbE family. This prokaryotic family of lipoproteins are related to ApbE from Salmonella typhimurium. ApbE is involved in thiamine synthesis. no signal. peptide no TMH; Family membership
YP_933889.1	Hypothetical membrane protein. No homology of the entire protein to the data bank. No domains predicted. signal peptide. 3 TMHs
YP_933890.1	Conserved hypothetical membrane protein. Homology to BB4221 of Bordetella bronchiseptica of 32% (trembl|Q7WFQ0). Has PF07331, Protein of unknown function (DUF1468);IPR009936;This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein
YP_933891.1	Conserved hypothetical membrane protein. Homology to an orf of R. palustris of 63% (tremblnew|CAE27761(SRS)). Has PF01970, Integral membrane protein DUF112;IPR002823:Members of this prokaryotic family have no known function. no signal peptide. 10 TMHs; Conserved hypothetical protein
YP_933892.1	Hypothetical membrane protein. no homology of the entire protein to the data bank. no domain predicted. no signal peptide. 4 TMHs
YP_933893.1	Probable Molybdenum-pterin binding protein II. Organosulfonate utilization protein SsuF InterPro: Molybdenum-pterin binding domain TIGRFAM: Mop: molybdenum-pterin binding domain; High confidence in function and specificity
YP_933894.1	Conserved hypothetical protein. Homology to Daro03001711 of Dechloromonas aromatica of 36% (gi|53730477|ref|ZP_00348804.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_933895.1	Part of the ABC transporter complex tauABC involved in taurine as a sulfur source import. Similar to the putative aliphatic sulfonates periplasmic-binding protein tauA in E.coli. Probably also involved in nitrate and bicarbonate transport.; Function unclear
YP_933896.1	Part of the ABC transporter complex tauABC involved in taurine import as a sulfur source.Probably responsible for energy coupling to the transport system.Similar to the aliphatic sulfonate transport membrane protein, tauB in E.coli. Probably also involved in nitrate and bicarbonate transport.; High confidence in function and specificity
YP_933897.1	Part of the ABC transporter complex tauABC involved in taurine import as sulfur source. Probably responsible for the translocation of the substrate across the membrane.Similar to the aliphatic sulfonate permease, tauC in E.coli. Probably also involved in nitrate and bicarbonate transport.; High confidence in function and specificity
YP_933898.1	Hypothetical membrane protein. Homology to COG2143 from 114 aa to 228 aa. InterPro: Thioredoxin (IPR006662). no signal peptide. 1 TMH
YP_933899.1	Phenylacetate-coenzyme A ligase (PA-CoA ligase).Coenzyme F390 synthase. CATALYZES THE ACTIVATION OF PHENYLACETIC ACID TO PHENYLACETYL-COA. InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity
YP_933900.1	Putative outer membrane TonB-dependent receptor protein. 43% TonB_receptor. Pfam:PF00593; TonB_dep_Rec; 1.; Function unclear
YP_933901.1	Conserved hypothetical signaling protein,; Conserved hypothetical protein
YP_933902.1	Conserved hypothetical protein. Homology to rsc1344 of R. solanacearum of 42% (trembl|Q8XZQ1). no domains predicted. no signal peptide. no TMHs
YP_933903.1	Cysteine synthase A,; High confidence in function and specificity
YP_933904.1	Putative TonB outer membrane receptor protein.31% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present.; Function unclear
YP_933905.1	Conserved hypothetical secreted protein. Homology to rsp0812 of R. solanacearum of 30% (trembl|Q8XRL9). no damians predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_933906.1	Putative sensor-regulator protein,; Specificity unclear
YP_933907.1	Probable two-component response regulator,; High confidence in function and specificity
YP_933908.1	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs
YP_933909.1	Probable organic hydroperoxide resistance protein. Homology to ohr of X. campestris of 50% (SWISSPROT:OHR_XANAC). Organic hydroperoxide detoxification protein. Confers increased resistance to tert-butyl hydroperoxide killing. InterPro: OsmC-like protein (IPR003718) Pfam: OsmC-like protein no signal peptide no TMH; High confidence in function and specificity
YP_933910.1	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
YP_933911.1	Bkd operon transcriptional regulator, similarity to SWISSPROT: (38% Pseudomonas putida, bkd operon transcriptional regulator BdkR) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_933912.1	Hypothetical sensor protein,; Conserved hypothetical protein
YP_933913.1	Conserved hypothetical sodium:solute sympoter. Homology to bb3915 of B. bronchiseptica of 57% (trembl|Q7WCM0). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. Tigrfam: sss: SSS sodium solute transporter superfamily. Pfam: Sodium:solute symporter family. signal peptide. 13 TMHS; Family membership
YP_933914.1	DNA polymerase III epsilon chain-like protein (EC 2.7.7.7). DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THE EPSILON SUBUNIT CONTAIN THE EDITING FUNCTION AND IS A PROOFREADING 3-5 EXONUCLEASE (BY SIMILARITY). dnaq: DNA polymerase III epsilon sub; Family membership
YP_933915.1	Transcriptional regulatory protein yycF. Member of the two-component regulatory system yycG/yycF involved in the regulation of the ftsAZ operon. Binds to the ftsAZ P1 promoter sequence. Similar to SWISSPROT: sprot|YYCF_BACSU (50% Bacillus subtilis, transcriptional regulatory protein YycF) / sprot|PHOP_BACSU (47% Bacillus subtilis, alkaline phosphatase synthesis transcriptional regulatory protein PhoP) InterPro: IPR001789 Response_reg. Pfam: PF00072 Response_reg.; Specificity unclear
YP_933916.1	Sensor histidine kinase mtrB (EC 2.7.3.-). Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals (By similarity). TREMBLnew:AAS80811; TREMBL:Q8PEZ5, 42% identity, 59% similarity; Pfam: Histidine kinase _,Phosphoacceptor domain. TIGRFAM: sss: sodium solute transporter sup. TMHMM predicted transmembrane helices. sss: SSS sodium solute transporter sup; Specificity unclear
YP_933917.1	Conserved hypothetical membrane protein. Homolgy to ttc0464 of T. thermophilus of 46% (tremble:Q72K63). no domains predicted. singal peptide. 1 TMH; Conserved hypothetical protein
YP_933918.1	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA
YP_933919.1	Putative fumarate hydratase. Homology to fumB of E. coli of 25% (sprot|FUMB_ECOLI). It functions in the generation of fumarate for use as an anaerobic electron acceptor. Tigrfam: ttdA_fumA_fumB: hydro-lyases Fe-S type,tartrate/fumarate subfamily, alpha region; ttdB_fumA_fumB: hydro-lyases Fe-S type, tartrate/fumarate subfamily, beta region no signal peptide no TMHs; Family membership
YP_933920.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_933921.1	NnrS is a putative heme-Cu protein and a member of the short-chain dehydrogenase family, probably involved in the nitric oxide metabolism. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase. 40% NnrS. TMhelix:10 Pfam:PF05940; NnrS; 1.; Function unclear
YP_933922.1	D-erythrose 4-phosphate dehydrogenase(E4PDH), GapB protein. Could play a role in pyridoxal 5-phosphate synthesis.Involved in the reaction: d-erythrose 4-phosphate + nad(+) = 4-phosphoerythronate + nadh. 51% E4PD_g-proteo.IPR000173; GAP_dhdrogenase. Pfam:PF00044; gpdh; 1.PF02800; gpdh_C; 1. TIGR00274: glucokinase regulator-relate. TIGRFAMs:TIGR01532; E4PD_g-proteo; 1.; High confidence in function and specificity
YP_933923.1	LysR-type transcriptional regulator NahR. Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes. Belongs to the LysR family of transcriptional regulators. Similar to SWISSPROT: sprot|NAHR_PSEPU (40% Pseudomonas putida, hth-type transcriptional activator NahR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; Specificity unclear
YP_933924.1	Involved in catabolism of naphthalene via gentisate to fumarate and pyruvate. NagI is a gentisate 1,2-dioxygenase which converts gentisate to maleylpyruvate. Similar to TREMBL:O86041 (66% identity); TREMBL:Q8X655 (30% identity); TREMBL:Q8Y0F7 (33% identity).; High confidence in function and specificity
YP_933925.1	Involved in catabolism of naphthalene via gentisate to fumarate and pyruvate. NagK is a fumarylpyruvate hydrolase which hydrolyzes fumarylpyruvate to fumarate and pyruvate. Similar to TREMBL:O86042 (67% identity); TREMBL:O07877 (63% identity); TREMBL:Q8G387 (50% identity). Pfam (PF01557): Fumarylacetoacetate (FAA) hydrolase family.; High confidence in function and specificity
YP_933926.1	catalyzes the formation of catechol from salicylate
YP_933927.1	maleylpyruvate isomerase. Homology to nogL of Ralstonia sp U of 73% (AAD12621) NagL is a reduced glutathione-dependent maleylpyruvate isomerase catalyzing the isomerization of maleylpyruvate to fumarylpyruvate. InterPro: Glutathione S-transferase N terminus (IPR004045) Pfam: Glutathione S-transferase, N-terminale domaine no signal peptide no TMHs; High confidence in function and specificity
YP_933928.1	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 23% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present.; Specificity unclear
YP_933929.1	TRAP-type C4-dicarboxylate transport system, small permease component. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 22% DctM.IPR007387; DctQ.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF04290; DctQ; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1.; Specificity unclear
YP_933930.1	Similar to a putative large integral C4-dicarboxylate membrane transport protein from W. succinogenes.DctM: TRAP dicarboxylate transporter. TREMBL:Q9ZEJ2 InterPro:IPR010656; DctM.IPR000252; DedA.IPR000524; HTH_GntR.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. TMHelix: 12. Signal peptide:present.; Specificity unclear
YP_933931.1	Conserved hypothetical membrane protein. Homology to BB1720 of Bordetella bronchiseptica of 32% (trembl|Q7WLM5). Has PF03992, Antibiotic biosynthesis monooxygenase;IPR007138;This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 (Q9X9W3) is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue. TMHMM2 reporting 2 TMH's Present. No Signal Peptide present.; Conserved hypothetical protein
YP_933932.1	Conserved hypothetical secreted protein. Homology to an orf of T. aromatica of 48% (trembl|Q7B0A2). no domains. signal peptide. no TMHs; Conserved hypothetical protein
YP_933933.1	4-oxalocrotonate tautomerase (EC 5.3.2.-) (4-OT). Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate. SPROT:Q9RHM8: 80% identity; 88% similarity InterPro: 4-oxalocrotonate tautomerase InterPro:IPR004370; Taut. ProDom: PD404143; Taut Pfam; PF01361; Tautomerase; 1. taut: 4-oxalocrotonate tautomerase helixturnhelix: reporting nucleic acid binding motif No transmembrane helices; High confidence in function and specificity
YP_933934.1	Similar to TREMBL:Q93JW1 (67% identity); TREMBL:Q9RHN0 (67% identity); SWISSPROT:P49155 (59% identity). Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity
YP_933935.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_933936.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_933937.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8XUP8 (61% identity); TREMBL:Q9I400 (57% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR) superfamily. InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933938.1	Conversion of 2-hydroxypent-2,4-dienoate into 4-hydroxy-2-oxopentanoate. Meta-cleavage pathway for the degradation of phenols, cresols and catechol. Belongs to the todj/xyli/xylj/hpcg family. Similar to TREMBL:Q93JW5 (75% identity); TREMBL:Q9ZI58 (65% identity); SWISSPROT:P23107 (73% identity). InterPro (IPR002607): Hydratase/decarboxylase Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity
YP_933939.1	2-hydroxymuconic semialdehyde dehydrogenase (HMSD). Homology to nahI of P. stutzeri of 73% (TREMBL:Q9S602) 2-HYDROXYMUCONIC ACID SEMIALDEHYDE CAN BE CONVERTED TO 2-HYDROXYPENT-24-DIENOATE EITHER DIRECTLY BY THE ACTION OF 2-HYDROXYMUCONIC SEMIALDEHYDE HYDROLASE (HMSH) OR BY THE ACTION OF THREE SEQUENTIAL ENZYMES THE FIRST OF WHICH IS HMSD. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs proA: gamma-glutamyl phosphate reductas
YP_933940.1	Conserved hypothetical protein. Homology to orf4 of P. putida of 59% (trembl|Q93JW8). Pfam: DUF336. This family contains uncharacterised sequences, including several GlcG proteins. The alignment contains many conserved motifs that are suggestive of cofactor binding and enzymatic activity. no signal peptide. no TMHs
YP_933941.1	Transcriptional regulator,; High confidence in function and specificity
YP_933942.1	In Pseudomonas sp. strain KL28 the genes,designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. Catechol 2,3-dioxygenase LapB,; High confidence in function and specificity
YP_933943.1	Probable phenol hydroxylase (EC 1.14.13.7) (Phenol 2-monooxygenase P5 component). Probable electron transfer from NADPH via FAD and the 2Fe-2S center to the oxygenase activity site of the enzyme. InterPro: Oxidoreductase FAD and NAD(P)-binding domain hisT_truA: tRNA pseudouridine synthase A; Specificity unclear
YP_933944.1	Pseudomonas sp. phenol hydroxylase P4 protein (EC 1.14.13.7, (phenol 2-monooxygenase P4 component). CATABOLIZES PHENOL AND SOME OF ITS METHYLATED DERIVATIVES. P4 IS REQUIRED FOR GROWTH ON PHENOL AND FOR IN VITRO PHENOL HYDROXYLASE ACTIVITY.; High confidence in function and specificity
YP_933945.1	Probable phenol hydroxylase subunit,68% identity(84% similarity) to trEMBL:Q9RAF6,Phenol hydroxylase component [phyC] [Ralstonia sp. KN1]. TrEMBL;Q9ZNP4 Has PF02332:Methane/Phenol/Toluene Hydroxylase;IPR003430;Bacterial phenol hydroxylase (EC: 1.14.13.7) is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives. This family contains both the P1 and P3 polypeptides of phenol hydroxlase and the alpha and beta chain of methane hydroxylase A. Methane hydroxylase A (EC: 1.14.13.25) is responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyses the monohydroxylation of a variety of unactivated alkenes,alicyclic, aromatic and heterocyclic compounds. Also included in this family is toluene-4-monooxygenase system protein A (EC: 1.14.13.-), which hydroxylates toluene to form P-cresol. PF04945:IPR007029; YHS domain; This short presumed domain is about 50 amino acid residues long. It often contains two cysteines that may be functionally important. This domain is found in copper transporting ATPases, some phenol hydroxylases and in a set of uncharacterised membrane proteins including Q9CNI0. This domain is named after three of the most conserved amino acids it contains. The domain may be metal binding,possibly copper ions. This domain is duplicated in some copper transporting ATPases.; High confidence in function and specificity
YP_933946.1	Probable phenol hydrolase, subunit P2. Catabolizes phenol and some of its methylated derivatives. p2 is required for growth on phenol, and for in vitro phenol hydroxylase activity. Similar to SWISSPROT:P19731 (47% similarity,71% identity). Pfam (PF02406): MmoB/DmpM family.; High confidence in function and specificity
YP_933947.1	Probable Phenol hydroxylase, subunit P1,65% identity(69% similarity) to TrEMBL;Q7WYF3 LapL [lapL] [Pseudomonas sp. KL28]. Has PF02332;Methane/Phenol/Toluene Hydroxylase domain;IPR003430: Bacterial phenol hydroxylase (EC: 1.14.13.7) is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives. This family contains both the P1 and P3 polypeptides of phenol hydroxlase and the alpha and beta chain of methane hydroxylase A. Methane hydroxylase A (EC: 1.14.13.25) is responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyses the monohydroxylation of a variety of unactivated alkenes,alicyclic, aromatic and heterocyclic compounds. Also included in this family is toluene-4-monooxygenase system protein A (EC: 1.14.13.-), which hydroxylates toluene to form P-cresol. No signal peptide or TMH reported to be present.; Family membership
YP_933948.1	Putative phenol hydroxylase, subunit P0. Homology to poxA of R. eutropha of 34% (trembl:O84958) This family consists of several bacterial phenol hydroxylase subunit proteins which are part of a multicomponent phenol hydroxylase. Some bacteria can utilise phenol or some of its methylated derivatives as their sole source of carbon and energy. The first step in this process is the conversion of phenol into catechol. Catechol is then further metabolised via the meta-cleavage pathway into TCA cycle intermediates. Pfam: Phenol hydrolase subunit no signal peptide no TMHs; Family membership
YP_933949.1	Probable ferredoxin-like protein. Homology to poxG of R. eutropha of 56% (trembl|O84964) The ferredoxins are iron-sulphur proteins that transfer electrons in a wide variety of metabolic reactions. Pfam: 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership
YP_933950.1	Transcriptional regulatory protein probable involved into the phenol degradation pathway,; High confidence in function and specificity
YP_933951.1	pobR. Transcriptional regulator AraC family. InterPro: AraC type helix-turn-helix pdxH: pyridoxamine 5-phosphate oxidase; Function unclear
YP_933952.1	catalyzes the formation of protocatechuate from 4-hydroxybenzoate
YP_933953.1	Putative two component response regulator,; Conserved hypothetical protein
YP_933954.1	Putative two-component system sensor protein,; Function unclear
YP_933955.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q98J95 (48% identity); TREMBL:Q8YZV3 (43% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. PFAM (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_933956.1	Conserved hypothetical protein, 31% identity (51% similarity) to TrEMBL;Q6NAA7. Has PF02637, GatB/Yqey domain;IPR003789:This domain is found in GatB and proteins related to bacterial Yqey P54464. It is about 140 amino acid residues long. This domain is found at the C terminus of GatB O30509 which transamidates Glu-tRNA to Gln-tRNA. The function of this domain is uncertain. It does however suggest that Yqey and its relatives have a role in tRNA metabolism. No Signal peptide or TMH present.; Function unclear
YP_933957.1	Probable negative transcriptional regulator,; Family membership
YP_933958.1	Hypothetical secreted protein no homology of the entire protein to the data bank no domains predicted signal peptide no TMHs
YP_933959.1	Putative two-component response regulator,; Specificity unclear
YP_933960.1	Putative two-component system sensor protein,; Function unclear
YP_933961.1	Putative sensory box histidine kinase,; Function unclear
YP_933962.1	Putative transcriptional regulator, LuxR family,very low similarity to SWISSPROT: sprot|NARP_ECOLI (16% Escherichia coli, NarP) InterPro: IPR000792 HTH_LuxR. Pfam: PF00196 GerE. Signal P reporting signal peptide. HTH reporting nucleic acid binding motif.; Function unclear
YP_933963.1	Hypothetical protein, has very weak homolgy with hits in the database. NO motifs,domains, signal peptide or TMH present.
YP_933964.1	Conserved hypothetical protein. Homology to mll6891 of Mesorhizobium loti of 37% (gi|14026496|dbj|BAB53093.1|). No domains predicted. No TMHs. No signal peptide.
YP_933965.1	Conserved hypothetical protein. Homology to mll6889 of M.loti. of 58% (trembl|Q987V8(SRS)). No domains predicted. No TMHs. No signal peptide.
YP_933966.1	Hypothetical secreted protein. No homology of the entire protein to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_933967.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs
YP_933968.1	Conserved hypothetical protein. Homology to mll6883 of M.loti of 58% (trembl|Q987W1(SRS)). No domains predicted. No TMHs. No signal peptide.
YP_933969.1	Hypothetical protein. No homology to the data base. No domains predicted. No signal peptide. No TMHs.
YP_933970.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_933971.1	Conserved hypothetical protein. Homology to mll6881 of M.loti of 49% (trembl|Q987W3(SRS)). No domains predicted. No TMHs. No signal peptide.
YP_933972.1	Conserved hypothetical transcriptional regulator. Homology to pp3544 of P. putida of 56% (trembl|Q88H21). InterPro: Aminotransferases class-I (IPR004838); Bacterial regulatory proteins, GntR family (IPR000524). Pfam: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II. no signal peptide. no TMHs; Family membership
YP_933973.1	Conserved hypothetical protein. Homology to bb1298 of B. brochiseptica of 64% (trembl|Q7WMU2). Pfam: Glyoxalase/Bleomycin restiant protein. no signal peptide. no TMHs
YP_933974.1	Conserved hypothetical L-lactate dehydrogenase (cytochrome). Homology to lldD of B. bronchisptica of 51% (tremble:Q7WND1). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Protein binding FMN and related compounds core region (IPR003009). Pfam: FMN-dependent dehydrognease. no signal peptide. no TMHs; Family membership
YP_933975.1	Ketopantoate reductase (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). TIGRFAM: apbA_panE: 2-dehydropantoate 2-reductase Pfam: ApbA: Ketopantoate reductase PanE/ApbA; High confidence in function and specificity
YP_933976.1	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 22% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present. TMHelix:1; High confidence in function and specificity
YP_933977.1	Probable benzaldehyde dehydrogenase [NAD+] (EC 1.2.1.28). Homology to xylC of P. putida of 53% (sprot|XYLC_PSEPU). CATALYTIC ACTIVITY: Benzaldehyde + NAD(+) + H(2)O = benzoate + NADH. Interpro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs proA: gamma-glutamyl phosphate reductas; Family membership
YP_933978.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
YP_933979.1	Transcriptional regulator,; High confidence in function and specificity
YP_933980.1	Putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to rdxA of R. sphaeroides of 37% (SWISSPROT:RDXA_RHOSH) Involved in a membrane generated redox signal. Pfam: 4Fe-4S binding domain Probable 5 TMHs no signal peptide; Family membership
YP_933981.1	Putative hypothetical protein. Has extremely weak homologs in the the database. No signaficant known doamins,motifs or signal peptide present.
YP_933982.1	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 34% MFS.IPR005829; Sug_transporter.IPR010916;TONB_Box_N. TMHelix:9.; Function unclear
YP_933983.1	Conserved hypothetical membrane protein. Homology to VV12384 of Vibrio vulnificus of 60% (trembl|Q8DA26). No domains predicted. TMHMM2 reporting 1 TMH present. No signal peptide present.; Conserved hypothetical protein
YP_933984.1	Putative TetR family transcriptional regulator,; Family membership
YP_933985.1	Conserved hypothetical membrane protein,; Conserved hypothetical protein
YP_933986.1	Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Conserved hypothetical protein
YP_933987.1	Conserved hypothetical secreted protein. Homology to Magn03007875 of Magnetospirillum magnetotacticum of 31% (gi|46202369|ref|ZP_00208493.1|(NBCI ENTREZ)). No domains predicted. Signal Peptide is reported to be Present, by Signal P program. No TMH reported present.; Conserved hypothetical protein
YP_933988.1	Putative response regulator,; Family membership
YP_933989.1	Conserved hypothetical protein. Homology to eca2717 of E. carotovora of 35% (tremble:Q6D3M7). no domains predicted. no signal peptide. no TMHs
YP_933990.1	Phosphoenolpyruvate synthase(Pyruvatewater dikinase)(PEP synthase). Essential step in gluconeogenesis when pyruvate and lactate are used as a carbon source.Catalytic activity:atp + pyruvate + h(2)o = amp + phosphoenolpyruvate + phosphate. 25% PEP_mobile.IPR006319; PEP_synth.IPR000121;PEP_utilizers.IPR002192; PPDK_N_term. Pfam:PF00391; PEP-utilizers; 1.PF02896; PEP-utilizers_C; 1. PF01326; PPDK_N; 1. TIGRFAMs:TIGR01418; PEP_synth; 1.; High confidence in function and specificity
YP_933991.1	Putative TetR family transcriptional regulator,; Family membership
YP_933992.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_933993.1	Integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions(sodium symporters). Hypothetical E.coli protein yfbS. Similar to TrkA. The NAD+ -binding protein TrkA is a component of a low-affinity K+ uptake system in Escherichia coli. This protein has the TrkA-C and TrkA-N domains. dass: anion transporter; High confidence in function and specificity
YP_933994.1	Putative Thioredoxin. Homology to txn (THIO_ICTPU) of I. punctatus of 36%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. InterPro: Thioredoxin (IPR0006662) Tigrfam: dsbE: periplasmic protein thiol:disulfie Oxidoreductase, DSB subfamily Pfam: Thioredoxin no signal peptide no TMHs; Family membership
YP_933995.1	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 65% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity
YP_933996.1	Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein beta-subunit (IPR000049) Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity
YP_933997.1	Entry name:- TREMBL:Q8XXS1 InterPro IPR002539; MaoC_dehydratas. Pfam PF01575; MaoC_dehydratas; 1. Identities = 74/154 (48%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0
YP_933998.1	The aidB gene encodes a protein of ca. 60 kDa that is homologous to several mammalian acyl coenzyme A dehydrogenases. Reaction:- acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor Entry name SWISSPROT:AIDB_ECOLI InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Identities = 85/289 (29%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_933999.1	4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23). This family contains a wide variety of enzymes,principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3 InterPro:IPR008272; 4HBcoA_thiost_AS. IPR006683; Thioestr_supf. Pfam:PF03061; 4HBT InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site No signal peptide No transmembrane helices TIGR00051: conserved hypothetical protein; High confidence in function and specificity
YP_934000.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear
YP_934001.1	Thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA (By similarity). Entry name PAAJ_ECOLI Primary accession number P77525 Identity: 150/410 (36%) InterPro IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership
YP_934002.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_934003.1	catalyzes the conversion of ferulic acid to feruloyl-CoA
YP_934004.1	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar sprot|LIVK_ECOLI (21%) and to trembl|Q9RYP6 (50%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_934005.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (66%) and to trembl|Q89PQ7 (62%). Smart: AAA ATPases; Specificity unclear
YP_934006.1	Probable branched-chain amino acid ABC transporterATP binding protein,; Specificity unclear
YP_934007.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W5E8 (62%), to sprot|BRAD_PSEAE (25%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting nine Tmhelix.; Specificity unclear
YP_934008.1	Putative TetR family transcriptional regulator,; Family membership
YP_934009.1	Putative TetR family transcriptional regulator,; Family membership
YP_934010.1	Conserved hypothetical protein. The highly identitcal hits such as Hypothetical Proteins of TrEMBL;Q8XXB7,Q6N0V6(80% identity) do not share all the domains as this Protein. Has Carboxymuconolactone decarboxylase family;IPR003779, CMD:The catechol and protocatechuate branches of the 3-oxoadipate pathway,which areimportant for the bacterial degradation of aromatic compounds, converge at the common intermediate 3-oxoadipate enol-lactone. Carboxymuconolactone decarboxylase is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway.; Specificity unclear
YP_934011.1	Hypothetical membrane protein. no homology of the entire protein to the data bank. no domains predicted. no signal peptide. 2 TMHS
YP_934012.1	Conserved hypothetical protein. Homology to Daro03003856 of Dechloromonas aromatica of 41% (gi|46140330|ref|ZP_00203564.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs
YP_934013.1	Conserved hypothetical protein. Homology to cv0086 of C. violaceum of 76% (trembl|Q7P1X6). no signal peptide. no TMHs. No domains reported.
YP_934014.1	Bacterial ring hydroxylating dioxygenase,small subunit. Similar to AlcE: iron-sulfur-containing dioxygenases, probably involved in alcaligin biosynthesis pathway in Bordetella species. Putative iron-sulfure protein involved in aromatic compounds degradations. Rieske [2Fe-2S] domain present. Probable Choline monooxygenase chloroplast precursor (EC 1.14.15.7). nadp_idh_euk: isocitrate dehydrogenase; Function unclear
YP_934015.1	Iron-regulated outer membrane protein. TonB-dependent receptor protein. Homolog to fpvA, a ferripyoverdine receptor precursor in P. aeruginosa. Similar to PupA protein of P. putida WCS,this protein is a receptor for the iron-bound form of pesudobactin, a compound structurally very; High confidence in function and specificity
YP_934016.1	Probable FecR-like transmembrane sensor involved in iron metabolism. FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm.; High confidence in function and specificity
YP_934017.1	Probable fecI-like RNA polymerase sigma factor. THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. THIS SIGMA FACTOR REGULATES THE FEC GENES FOR IRON DICITRATE TRANSPORT (PROBABLE). InterPro: Sigma factor ECF subfamily; Specificity unclear
YP_934018.1	Naphthalene 12-dioxygenase system ferredoxin component. COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. THIS SUBUNIT IS A 2FE-2S FERREDOXIN THAT TRANSFERS ELECTRONS TO IRON SULFUR PROTEIN COMPONENTS (ISP).; High confidence in function and specificity
YP_934019.1	NagH: probable salicylate-5-hydroxylase small oxygenase component oxidoreductase. Involved in conversion of Naphthalene to gentisate. Aromatic compounds degradation.; Family membership
YP_934020.1	nagG,RSc1090:putative salicylate-5-hydroxylase large oxygenase component oxidoreductase [EC:1.-.-.-]. Rieske-type iron-sulfur center homologous to the large subunits of dihydroxylating dioxygenases. Involved in conversion of Naphthalene to gentisate. Aromatic compounds degradation. Biphenyl dioxygenase alpha subunit (EC 1.14.12.18) (Biphenyl 23- dioxygenase).; High confidence in function and specificity
YP_934021.1	Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH.; High confidence in function and specificity
YP_934022.1	LysR-type transcriptional regulator NahR Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes. Similar to SWISSPROT: sprot|NAHR_PSEPU (61% Pseudomonas putida, nahR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_934023.1	TRAP-type C4-dicarboxylate transport system, large permease component,DctM. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 25% DctM.IPR000252; DedA.IPR000524; HTH_GntR.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. TMHelix: 11.; Specificity unclear
YP_934024.1	Conserved hypothetical membrane protein. Homology to PM1526 of Pasteurella multocida of 32% (trembl|Q9CKT0(SRS)). Pfam: PF04290;IPR007387;Tripartite ATP-independent periplasmic transporters, DctQ component; The function of the members of this family is unknown, but DctQ homologues are invariably found in the tripartite ATP-independent periplasmic transporters. No signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934025.1	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 23% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present.; Specificity unclear
YP_934026.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_934027.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_934028.1	Transcriptional regulator, LysR family,; Specificity unclear
YP_934029.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. Pfam: Endo/excinuclease amino terminal domain. no signal peptide. no TMHs. HTH predicted
YP_934030.1	Transcriptional regulator, AraC family,; High confidence in function and specificity
YP_934031.1	Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450.; Family membership
YP_934032.1	Probable ferredoxin. Homology to fdxP of C. crescentus of 51% (sprot|FER2_CAUCR). Ferredons are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: Ferredoxin (IPR001041),Adrenodoxin (IPR001055) Pfam: 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_934033.1	Probable putidaredoxin reductase (EC 1.18.1.-). Homology to camA of P. putida of 48% (sprot|CAMA_PSEPU). The oxidation of camphor by cytochrome p450-cam requires the participation of a flavoprotein, putidaredoxin reductase, and an iron-sulfur protein, putidaredoxin, to mediate the transfer of electrons from nadh to p450 for oxygen activation. Interpro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IRP001327), NAD binding site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership
YP_934034.1	Hypothetical protein yqgX. 65% identity, 75% similarity to conserved hypothetical protein (TREMBL:Q7P219) InterPro; TREMBL:Q7WQV2; Metallo-beta-lactamase superfamily. Pfam: Aminotransferase class III; helper component proteinase TREMBL:Q9DCMO-RIKEN cDNA; TREMBL:Q9A911 - GlyoxlaseII superfamily protein. TIGR00162: conserved hypothetical protein. Signal peptide-nonsecretory protein; Transmembrane helices present.; Function unclear
YP_934035.1	Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group
YP_934036.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934037.1	Flagellin (Phase-1-D flagellin). Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. InterPro: Flagellin N-terminus,Flagellin C-terminus Pfam: Bacterial flagellin N-terminus,bacterial flagellin C-terminus no signal peptide no TMH; Family membership
YP_934038.1	Putative malonate transporter. TREMBL:Q7ML40: 38% identity, 55% similarity SPROT:P56949: 27% identity, 44% similarity subcellular location:integral membrane protein (potential). similarity:belongs to the auxin efflux carrier (tc 2.a.69) family. InterPro:IPR004776; Auxin_eff. Pfam: PF03547; Auxin_eff; GntP_permease;GntP family permease (Pfam) 2a69: Auxin Efflux Carrier Signal P predicted signal peptide and TMHMM predicted 10 transmembrane helices; Specificity unclear
YP_934039.1	Probable aldo-keto reductase. Homology to yakC of S.pombe of 43% (sprot|YAKC_SCHPO). Catalyze the reduction of 2-nitorbenzaldehyde, pyridine-2-aldehyde and 2-phthaladehyde. Pfam: Aldo/Keto reductase signal peptide no TMHs; Family membership
YP_934040.1	Hypothetical oxidoreductase yrbE (EC 1.-.-.-). TREMBL:Q93PS4:90% identity; 93% similarity. This group of enzymes utilise NADP or NAD, and is known as the GFO/IDH/MOCA family in Swiss-Prot. GFO is a glucose--fructose oxidoreductase, which converts D-glucose and D-fructose into D-gluconolactone and D-glucitol in the sorbitol-gluconate pathway. MOCA is a rhizopine catabolism protein which may catalyze the NADH-dependent dehydrogenase reaction involved in rhizopine catabolism. Other proteins belonging to this family include Gal80, a negative regulator for the expression of lactose and galactose metabolic genes; and several hypothetical proteins from yeast, Escherichia coli and Bacillus subtilis. InterPro:IPR000683; GFO_IDH_MocA. IPR004104; GFO_IDH_MocA_C. Pfam: PF01408; GFO_IDH_MocA; 1. PF02894; GFO_IDH_MocA_C; presence of DUF206 Probably nonsecretory protein (SignalP predicted) Number of predicted TMHs: 0 (TMHMM predicted) InterPro: Oxidoreductase N-terminal ubiX: phenylacrylic acid decarboxylase 3; High confidence in function and specificity
YP_934041.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_934042.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_934043.1	Probable 2-pyrone-4,6-dicarboxylate hydrolase. Homology to ligI of S. paucimobilis of 55% (tremble:O87170) Pfam: Amidohydrolase no signal peptide no TMHs; High confidence in function and specificity
YP_934044.1	Activity:- 3-hydroxy-2-methylpropanoate + NAD = 2-methyl-3-oxopropanoate + NADH2 Entry name SWISSPROT:MMSB_PSEAE InterPro IPR002204; 3hydroxisobut_dh. IPR006115; 6PGD_NAD. Pfam PF03446; NAD_binding_2; 1. Identities = 48/218 (22%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_934045.1	Possible acyl transferase.; Family membership
YP_934046.1	4-oxalomesaconate hydratase These proteins are related to the metal-dependent hydrolase superfamily tremblnew|CAE30137: 86% identity, 93% similarity InterPro:IPR006992; Amidohydro_2. Pfam:PF04909; Amidohydro_2 Absence of traansmembrane helices (TMHMM predicted); High confidence in function and specificity
YP_934047.1	PcaK:4-hydroxybenzoate transporter. TRANSPORTER FOR 4-HYDROXYBENZOATE ALSO REQUIRED FOR CHEMOTAXIS TO AROMATIC ACIDS. Membership of the major facilitator superfamily of transport proteins. 2A0115: benzoate transport; High confidence in function and specificity
YP_934048.1	Hypothetical protein FldA, 78% identity (86% similarity) to TrEMBL;Q6N0R5,Q8PF30(47% identity). 45% identity to ybhH of SwissProt;P75762(E.coli) Has PF04303,Protein of unknown function (DUF453);IPR007400; FldA (Q9L3A0) is thought to be involved in the degradation of the polyaromatic hydrocarbon fluorene by Sphingomonas sp. LB126. Has PF01678, Diaminopimelate epimerase;IPR001653 DAP_epimerase: Diaminopimelate epimerase contains two domains of the same alpha/beta fold, both contained in this family.Diaminopimelate epimerase (EC:5.1.1.7) catalyzes the isomeriazation of L,L- to D,L-meso-diaminopimelate in the biosynthetic pathway leading from aspartate to lysine. This enzyme is a protein of about 30 kDa. No signal peptide or TMH present.; Family membership
YP_934049.1	Bicyclomycin resistance protein homolog. Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). InterPro: General substrate transporters efflux_Bcr_CflA: drug resistance tran Also show similarity to bssH of bssDCABEFGH operon-genes involved in anaerobic degradation of toulene in denitryfing bacterium, Azoarcus strain EbN1; High confidence in function and specificity
YP_934050.1	Nitrogen assimilation regulatory protein nac (Nitrogen assimilation control protein). TRANSCRIPTIONAL ACTIVATOR FOR THE HUT PUT AND URE OPERONS AND REPRESSOR FOR THE GDH AND GLTB OPERONS IN RESPONSE TO NITROGEN LIMITATION. NEGATIVE REGULATOR OF ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|NAC_KLEAE (30% Klebsiella aerogenes, nitrogen assimilation regulatory protein nac (nitrogen assimilation control protein)) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; Specificity unclear
YP_934051.1	Probable methyl-accepting chemotaxis protein,; Specificity unclear
YP_934052.1	Getrichum candidum Dec1,Dye-decolorizing peroxidase,DyP, that lacks a typical heme-binding region. Responsible for the decoloration of dyes. DyP degraded phenolic compounds, such as 2,6-dimethoxyphenol and guaiacol. Hypothetical protein yfeX. ccoO: cytochrome c oxidase cbb3-type su; High confidence in function and specificity
YP_934053.1	tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA adenylyltransferase) (tRNA CCA-pyrophosphorylase) (CCA-adding enzyme). This enzyme carries out synthesis of the tRNA CCA terminus without the direction of a template using the multiple accepting and donating subsites within its active site.; Family membership
YP_934054.1	Putative malonate transporter. TREMBL:Q8ZCU0: 38% identity, 55% similarity SPROT:P56949:23% identity, 41% similarity InterPro:IPR004776; Auxin_eff. Pfam:PF03547; Auxin_ef Signal P predicted nonsecretory protein and TMHMM predicted 9 transmembrane helices. 2a69: Auxin Efflux Carrier; Specificity unclear
YP_934055.1	Conserved hypothetical membrane protein. Homology with PA3897 of P. aeruginosa of 30%. InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transport. Pfam: Integral membrane protein DUF6. probable 10 TMHs. no signal peptide; Conserved hypothetical protein
YP_934056.1	Tfp pilus retraction protein PilU, probable involved in the twitching motility mechanism,; High confidence in function and specificity
YP_934057.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. TMH in signal peptide
YP_934058.1	Putative outer membrane efflux protein. Homology to nodT from Rhizobium leguminosarum of 20% over 432 aa. The OEP family (Outer membrane efflux protein)allow export of a variety of substrates in Gram negative bacteria. Most members of NodT family are likely to export primarily small molecules rather than proteins. InterPro: Outer membrane efflux protein. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership
YP_934059.1	Specificity unclear
YP_934060.1	No Good Homology with any hits in the DB. Conserved Hypothetical Protein,34% similarity to TrEMBL;Q8E9W3. Has PF03160:IPR003644:Calx_beta;Na-Ca exchanger/integrin-beta4:This domain has been found in Na-Ca exchangers and integrin subunit beta4, as well as some cyanobacterial proteins. Has 3 CA(Cadherin repeats)domains;SMART:SM00112;IPR002126:Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium. Has 1 CADG,Dystroglycan-type cadherin-like domains(SMART;SM00736).Cadherin-homologous domains present in metazoan dystroglycans and alpha/epsilon sarcoglycans,yeast Axl2p and in a very large protein from magnetotactic bacteria. Likely to bind calcium ions.; Family membership
YP_934061.1	Similar to MacA.; Family membership
YP_934062.1	Family membership
YP_934063.1	Conserved hypothetical secreted protein. Homology to Mflag03001539 of Methylobacillus flagellatus of 38% (gi|45521149|ref|ZP_00172671.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_934064.1	Conserved hypothetical protein. Homology to rsc1124 of R. solanacearum of 59% (trembl|Q8Y0C0). no signal peptide. no TMHs. no domains reported.
YP_934065.1	Conserved hypothetical protein. Homology to dr0392 of D. radiodurans of 33% (trembl|Q9RXC3). Pfam: Collagen triple helix repeat (20 copies). Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. no signal peptide. no TMHs
YP_934066.1	Cytochrome c peroxidase (EC 1.11.1.5), an electron-transfer proteins having one or several haem c groups,bound to the protein by one or, more generally, two thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. CytC possess a wide range of properties and function in a large number of different redox processes. Signal peptide.; High confidence in function and specificity
YP_934067.1	Conserved hypothetical secreted secreted protein. Homology to bb1301 of B. bronchiseptica of 59% (trembl|Q7WMT9). Pfam: Lipoprotein_15. This family occurs as tandem repeats in a set of lipoproteins. The alignment contains a Y-X4-D motif. signal peptide. no TMHs; Conserved hypothetical protein
YP_934068.1	Putative RNA polymerase sigma factor,57% Identity to TrEMBL;Q7VV01, 49% Identity to TrEMBL;Q8XV48,53% to Q63LJ3. Has PF04542, Sigma-70 region 2; IPR007627,Sigma70_r2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit,beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation. Has PF04545, Sigma-70, region 4;IPR007630, Sigma70_r4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.
YP_934069.1	Conserved hypothetical membrane protein. Homology to BB1303 of Bordetella bronchiseptica of 50% (trembl|Q7WMT7). No domains predicted. TMHMM2 reporting 1 TMH present. No signal peptide present.; Conserved hypothetical protein
YP_934070.1	Hypothetical protein,53% identity to TrEMBL:Q8YF53,Hypothetical protein BMEI1674 [BMEI1674] [Brucella melitensis] Has IPR000157:TIR domain.; Family membership; ORF6
YP_934071.1	Putative LysR-family transcriptional regulator protein.62% identity to TrEMBL;Q63NK9,Q8XQV8,Q62B59,Q8VL17. PF00126, Bacterial regulatory helix-turn-helix protein, lysR family;IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse,but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB,lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR,pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini. Has PF03466, LysR substrate binding domain; IPR005119, LysR_subst; The structure of this domain is known and is
YP_934072.1	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership
YP_934073.1	AcrB/AcrD/AcrF family protein. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q92U15 (38% identity); TREMBL:Q7NE92 (38% identity). InterPro (IPR000731): Sterol-sensing 5TM box. InterPro (IPR004764): Hydrophobe/amphiphile efflux-1 HAE1. InterPro (IPR001036): Acriflavin resistance protein. Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear
YP_934074.1	Probable outer membrane efflux protein. Homology to opcM from B. cepacia of 40% Component of an efflux system that confers mutiple antibiotic resistence. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHS; Family membership
YP_934075.1	Conserved hypothetical protein. Homology to VV1824 of V.vulnificus of 37% (trembl:Q7MKG9). No domains predicted. No signal peptide or TMH reported present.
YP_934076.1	Hypothetical membrane protein. no homology to the data bank. no domains predicted. no signal peptide. 1 TMHs
YP_934077.1	A gene conferring resistance to fosmidomycin (Fs) encode a putative polypeptide of 406 amino acids (aa) with a molecular weight of 43303 in E.coli. 23% similarity to B. japonicum fsr. A comparison between the aa sequence of Fsr and sequences in a protein database revealed 18% homology to the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. Hydropathy analysis of the Fsr protein revealed twelve putative transmembrane segments. Fsr does not have any direct effect on the biosynthesis of isoprenoid in E. coli, and that the mechanism for FsR involves the efflux of the drug by a process that is facilitated by Fsr. (Ref: Fujisaki,S. et al., 1996); High confidence in function and specificity
YP_934078.1	Putative AraC-family transcriptional regulator,; Family membership
YP_934079.1	Putative two-component hybrid sensor and regulator,; Family membership
YP_934080.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_934081.1	Putative outer membrane lipoprotein OmlA precursor. Homology to omlA of P. aeruginosa of 33% (sprot|OMLA_PSEAE) MAY HAVE A STRUCTURAL ROLE IN MAINTAINING THE CELL ENVELOPE INTEGRITY. Pfam: SmpA/OmlA family no signal protein 1 TMH; Conserved hypothetical protein
YP_934082.1	Ferric uptake regulation protein (Ferric uptake regulator)Fur. Acts as a global negative controlling element employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E. InterPro: Ferric uptake regulator family TIGR00011: conserved hypothetical protein; High confidence in function and specificity
YP_934083.1	DNA repair protein recN (Recombination protein N). MAY BE INVOLVED IN RECOMBINATIONAL REPAIR OF DAMAGED DNA. recN: DNA repair protein RecN; High confidence in function and specificity
YP_934084.1	Probable inorganic polyphosphate/ATP-NAD kinase(Poly(P)/ATP NAD kinase). Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. 34% ATP_NADK.InterPro: Domain of unknown function DUF15 Pfam:PF01513; NAD_kinase; 1. TIGR:VC0853.; High confidence in function and specificity
YP_934085.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_934086.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_934087.1	Conserved hypothetical membrane protein. Homology to rs02279 of R. solanacearum of 53% (trembl|Q8Y388(SRS)). No domains predicted. No signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934088.1	Similar to TREMBL:Q7NTT5 (32% identity).
YP_934089.1	Putative serine/threonine kinase,; Family membership
YP_934090.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934091.1	Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline
YP_934092.1	Outer membrane protein P.III precursor (Gonococcal protein III) (PIII). InterPro: Bacterial outer membrane protein; High confidence in function and specificity
YP_934093.1	Involved in ubiquinone biosynthesis
YP_934094.1	Conserved hypothetical protein. Homology to ebA5327 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA5327(KEGG)). Pfam: Polysaccharide pyruvyl transferase Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. no signal peptide. no TMHs
YP_934095.1	Conserved hypothetical secreted protein. Homology to Daro03002418 of Dechloromonas aromatica of 58% (gi|53730135|ref|ZP_00150721.2|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.
YP_934096.1	Conserved hypothetical protein. Homology to Daro03002419 of Dechloromonas aromatica of 51% (gi|41723832|ref|ZP_00150722.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.
YP_934097.1	conserved hypothetical secreted protein. Homology to Daro03002420 of Dechloromonas aromatica of 39% (gi|41723833|ref|ZP_00150723.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_934098.1	Conserved hypothetical membrane protein. Homology to CV2219 of Chromobacterium violaceum of 36% (trembl|Q7NVX2(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein
YP_934099.1	Conserved hypothetical secreted protein. Homology to Daro03002422 of Dechloromonas aromatica of 63% (gi|41723835|ref|ZP_00150725.1|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.; Conserved hypothetical protein
YP_934100.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs
YP_934101.1	Hpyothetical protein with TIR domain. no homology to the data bank. Interpro: TIR domain Pfam: TIR doamin. Site directed mutagenesis and deletion analysis have shown that the TIR domain is essential for Toll and IL-1R activities. Sequence analysis have revealed the presence of three highly conserved regions among the different members of the family: box 1 (FDAFISY), box 2 (GYKLC-RD-PG), and box 3 (a conserved W surrounded by basic residues). It has been proposed that boxes 1 and 2 are involved in the binding of proteins involved in signaling,whereas box 3 is primarily involved in directing localization of receptor, perhaps through interactions with cytoskeletal elements. no signal. peptide 2 TMHs
YP_934102.1	Conserved hypothetical secreted protein. Homology to SMb20495 of S.meliloti of 45% (tremble:Q92W68). Has 3 TPR repeats(IPR001440)(SMART:SM00028):The tetratrico peptide repeat (TPR) is a structural motif present in a wide range of proteins. It mediates protein-protein interactions and the assembly of multiprotein complexes. The TPR motif consists of 3 tandem-repeats of 34 amino acids residues, although individual TPR motifs can be dispersed in the protein sequence. Sequence alignment of the TPR domains reveals a consensus sequence defined by a pattern of small and large amino acids. TPR motifs have been identified in various different organisms, ranging from bacteria to humans. Proteins containing TPRs are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control,mitochondrial and peroxisomal protein transport,neurogenesis and protein folding. No TMH being reported present. Signal peptide present.; Conserved hypothetical protein
YP_934103.1	Auxin-binding protein 1 precursor(ABP).This is probably a receptor for the plant hormone auxin. 34% Auxin_BP.IPR007113; Cupin_sup.IPR000886;ER_target_S. Pfam:PF02041; Auxin_BP; 1.; Function unclear
YP_934104.1	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 37% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear
YP_934105.1	Ferredoxin subunits of nitrite reductase. THIS SUBUNIT IS A 2FE-2S FERREDOXIN THAT TRANSFERS ELECTRONS TO IRON SULFUR PROTEIN COMPONENTS (ISP). Similar to nasE,from S.aureus_N315 a naphthalene 12-dioxygenase system ferredoxin component.; High confidence in function and specificity
YP_934106.1	Translation initiation factor IF-1. No specific function has so far been attributed to this initiation factor; however it seems to stimulate more or less all the activities of the other two initiation factors IF-2 and IF-3.; Family membership
YP_934107.1	Cold shock-like protein,; High confidence in function and specificity
YP_934108.1	Conserved hypothetical membrane protein. Homology to ORF62 of Pseudomonas of 60% (trembl|Q936Z8(SRS)). InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter. Pfam: Integral membrane protein DUF6. probable 9 TMHs. signal peptide; Conserved hypothetical protein
YP_934109.1	Conserved hypothetical membrane protein. Homology to cp98 of P. aeruginosa of 33% (tremblnew|AAP22587). no domains predicted. no signal peptide. 2 TMHs.; Conserved hypothetical protein
YP_934110.1	Conserved hypothetical membrane protein. Homology to gsu0250 of G. sulfurreducens of 46% (tremblnew|AAR33584). no domains predicted. no signal peptide. 3 TMHs.; Conserved hypothetical protein
YP_934111.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
YP_934112.1	42% Aldolase_II_N.Class II Aldolase and Adducin N-terminal domain. Pfam: PF00596; Aldolase_II; 1. TIGR: PP2871.; High confidence in function and specificity
YP_934113.1	Conserved hypothetical endonuclease/exonuclease/phosphatase family protein. Homology to RPBDRAFT_0804 of Rhodopseudomonas palustris HaA2 of 315. Pfam: Exo_endo_phos. Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18 e.g APEX1_HUMAN, DNase I proteins EC:3.1.21.1 e.g. DNAS1_HUMAN, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56 SYNJ1_HUMAN, Sphingomyelinase EC:3.1.4.12 PHL2_BACCE and Nocturnin NOCT_MOUSE. no TMHs. no signal peptide.; Conserved hypothetical protein
YP_934114.1	In E.coli this receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Binding of T5 triggers the opening of a high conductance ion channel. Can also transport the antibiotic albomycin. Signal peptide.; Specificity unclear
YP_934115.1	Conserved hypothetical membrane protein. Homology to rs00511 of R. solanacearum of 32% (trembl|Q8XUW6(SRS)). No domains predicted. singal peptide. 2 TMHs; Conserved hypothetical protein
YP_934116.1	GAF/GGDEF-domain containing protein,; Conserved hypothetical protein
YP_934117.1	Hypothetical protein, 50% identity (59% simialrity)to TrEMBL;Q92TJ5. Has PF04828, Protein of unknown function (DUF636);IPR006913, GFA;This family of proteins has no known function, but several strongly conserved cysteine residues. Glutathione-dependent formaldehyde-activating enzymes catalyze the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione. All known members of this family contain 5 strongly conserved cysteine residues. NO Signal peptide or TMH present.; Function unclear
YP_934118.1	Conserved hypothetical membrane protein. Homology to Saro02001549 of Novosphingobium aromaticivorans of 37% (gi|48849438|ref|ZP_00303681.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934119.1	Hypothetical protein,45% similarity to TrEMBL;Q6LHM7. No Good homology over entire length in the DB. No signal Peptide or TMH present.; Function unclear
YP_934120.1	Puatative Glyoxalase sub unit, 37% identitcal to TrEMBL;Q89MF5 Has PF00903, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I, catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid . The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyphenylpyruvate dioxygenase. No SIgnal Peptide or TMH reported present.; Family membership
YP_934121.1	TREMBL:Q89L44: 48% identity.64% similarity. probable haloacid dehalogenase-like hydrolase. InterPro:IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Phosphoglycolate phosphatase(PGP). TIGR00099: conserved hypothetical prot; Function unclear
YP_934122.1	Probable redox-sensitive transcriptional activator,; High confidence in function and specificity
YP_934123.1	Similar to TREMBL:Q98BY2 (39% identity); TREMBL:Q9A2R1 (40% identity); TREMBL:Q89KG6 (34% identity). Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Function unclear
YP_934124.1	Hypothetical membrane protein. no homology to the data bank. no domains predicted signal peptide. 3 TMHs
YP_934125.1	Conserved hypothetical protein. Homology to VPA0111 of V.parahaemolyticus of 62% (trembl:Q87JY7). Has (IPR010323)PF06041, Bacterial protein of unknown function (DUF924);This family consists of several hypothetical bacterial proteins of unknown function. NO signal peptide or TMH present.
YP_934126.1	Conserved hypothetical membrane protein,; Conserved hypothetical protein
YP_934128.1	Hypothetical truncated transposase. Homology to tnp23 of Azoarcus sp. EbN1 of 86% (gnl|keqq|eba:ebA2478(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_934129.1	Hypothetical truncated transposase. Homology to tnp23 of Azoarcus sp. EbN1 of 87% (gnl|keqq|eba:ebA2478(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_934130.1	Hypothetical truncated transposase. Homology to tnp23 of Azoarcus sp. EbN1 of 86% (gnl|keqq|eba:ebA2478(KEGG)). No domains predicted. No signal peptide. No TMHs.,; Family membership
YP_934131.1	Conserved hypothetical protein. Homology to an orf of Polaromanas sp JS666 of 41% No domain predicted. No signal peptide No TMHs
YP_934132.1	Hypothetical membrane protein. Homology to yptb3870 of Y. pseudotuberculosis of 29% (tremble:Q664A2). No domains predicted. No signal peptide. 1 TMHs
YP_934133.1	Conserved hypothetical protein. Homology to an orf of Exiguobacterium sp. 255-15 (ZP_00355791). No domains predicted. No signal peptide. 2 TMHs
YP_934134.1	with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism
YP_934135.1	Conserved hypothetical membrane protein. Homology to NE0632 of Nitrosomonas europaea of 42% (trembl|Q82WN6(SRS)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_934136.1	Conserved hypothetical membrane protein. Homology to PA1924 of P. aeruginosa of 43% (trembl|Q9I2I0(SRS)). No domains predicted. no signal peptide. probable 3TMHS; Conserved hypothetical protein
YP_934137.1	Probable trans-aconitate 2-methyltransferase. Homology to tam of E. coli of 48% (sprot|TAM_ECOLI). Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity). Pfam: PTS system, Lactose/Cellobiose specific no signal peptide no TMHs; High confidence in function and specificity
YP_934138.1	Hypothetical membrane protein. no homology to the data bank. no domains predicted. 1 TMHs. no signal peptide
YP_934139.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934140.1	TREMBL:Q7MF75: 35% identity; 50% similarity. IPR006323; Phosphonoacetaldehyde hydrolase IPR010976; Beta-phosphoglucomutase hydrolase This group of sequences represent part of one structural subfamily of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases (IPR005834). The superfamily is defined by the presence of three short catalytic motifs. Hypothetical protein yhcW. InterPro:IPR006402; HAD-SF-IA-v3. IPR005833; Halogease/hydrolase. Pfam: PF00702; Hydrolase Absence of signal peptide (Signal P predicted) and transmembrane helices (TMHMM predicted) IPR005834; Hydrolase. TIGR00099: conserved hypothetical protein; Family membership
YP_934141.1	Conserved hypothetical protein. Homology to RSc0334 of R. solanacearum of 59% (sprot:Y334_RALSO). Pfam: Appr-1-p processing enzyme. No signal peptide. No TMHs.
YP_934142.1	Conserved hypothetical ATPase. Homology to rsc1961 of R. solanacearum of 37% (trembl|Q8XY02). Pfam: Atpase familly associated with various cellular activities (domaine 1 from 300 aa to 499 aa, domaine 2 from 543 to 723 aa). no signal peptide. no TMHs; Conserved hypothetical protein
YP_934143.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934144.1	Putative transcriptional factor
YP_934145.1	Hypothetical protein. No homology to the data base. No domains predicted. No TMHs. No signal peptide.
YP_934146.1	Hypothetical protein, very weak homology with any hits in the database. Has , No domains, repeats, motifs or features could be predicted with confidence above threshold scores.
YP_934147.1	Putative dual specificity protein phosphatase,; Function unclear
YP_934148.1	Putative ADP-ribosyl-[dinitrogen reductase] hydrolase. Homology to draG of R. rubrum of 24% (sprot|DRAG_RHORU) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. Pfam: ADP-ribosylglycohydrolase no signal peptide no TMHs; High confidence in function and specificity
YP_934149.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934150.1	Conserved hypothetical protein. Homology to Bucepa03000629 of Burkholderia cepacia of 47% (gi|46324491|ref|ZP_00224852.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.
YP_934151.1	Similar to SWISSPROT:P71505 (50% identity),SWISSPROT:Q8X8L4 (49% identity). Pfam (PF01738): Dienelactone hydrolase family.; High confidence in function and specificity
YP_934152.1	Region start changed from 2926444 to 2926426 (-18 bases)
YP_934153.1	GGDEF family protein,; Conserved hypothetical protein
YP_934154.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. TMH in signal peptide
YP_934155.1	Conserved hypothetical protein. Homology to ebD23 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebD23(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_934156.1	Conserved hypothetical membrane protein. Homology to CC0717 of Caulobacter crescentus of 66% (trembl|Q9AA89(SRS)). Also homology to noduline 21 of G. max of 33% (sprot|NO21_SOYBN(SRS)). Has PF01988,(IPR008217)Integral membrane protein DUF125;This family of predicted integral membrane proteins has no known function. However it does include P47818, that may have a role in regulating calcium levels. no signal peptide. 5 TMHs; Conserved hypothetical protein
YP_934157.1	Probable low-affinity phosphate transporter protein, PitA. Involved in phosphate transport depending on the proton motive force in E.coli. Similar to Pho-4, a cation-phosphate symporter in N. crassa. InterPro: Phosphate transporter family Signal peptide.; High confidence in function and specificity
YP_934158.1	Glyoxalase family protein, 54% identity (67% similarity) to TrEMBL;Q88HB6. Has PF00903,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyphenylpyruvate dioxygenase.; Family membership
YP_934159.1	Hypothetical membrane protein. No homology of the entire protein to a protein of similar length. no domains predicted. singal peptie. 6 TMHs
YP_934160.1	Conserved hypothetical membrane protein. Homology to S1719 of Photobacterium profundum of 73% (tremblnew|CAG22368). Has PF02694, Uncharacterized BCR,YnfA/UPF0060 family;IPR003844;This entry describes integral membrane proteins of unknown function. no signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934161.1	Ferredoxin-NADP+ reductase (EC 1.18.1.2) Homology to fpr of A. vinelandii of 75% (sprot|FENR_AZOVI). CATALYTIC ACTIVITY: Reduced ferredoxin + NADP(+) = oxidized ferredoxin + NADPH. Interpro: Oxidoreductase FAD and NAD8P)-binding domain (IPR001433); NADH: cytochrome b5 reductase (CBR) (IPR001834) Pfam: Oxidoreductase FAD-binding doamin; Oxidoreductase NAD-binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_934162.1	Putative thioredoxin-disulfide reductase. Homology to trxA (ECs4714) of E. coli of 27%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a dislufide. InterPro: Thioredoxin (IPR006662) no TMHs; Family membership
YP_934163.1	Conserved hypothetical secreted protein. Homology to PJS6w01001981 of Polaromonas sp. JS666 of 70% (gi|54030965|ref|ZP_00363100.1|(NBCI ENTREZ)). No domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_934164.1	Hypothetical protein TC0109. TREMBL:Q8XTTO: 64% identity, 75% similarity. This entry describes a family of conserved hypothetical proteins with no known function. InterPro:IPR005247; Cons_hypoth481. IPR008914; PEBP. Pfam: PF01161; PBP Absence of signal peptide. Absence of TMH's; Function unclear
YP_934165.1	Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs
YP_934166.1	Conserved hypothetical protein. Homology to ebA2897 of Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA2897(KEGG)). Has PF01936, Protein of unknown function DUF88;(IPR002790). This highly conserved bacterial protein has no known function. The alignment contains many conserved aspartates, suggesting an enzymatic function such as an endonuclease or glycosyl hydrolase (Bateman A pers. obs). Coils2 Program predcit presence of Coiled Coil. No Signal Peptide or TMH present.
YP_934167.1	Conserve peroxiredoxin. Homology to mll2432 of M. loti of 74% (trembl|Q98IF0). Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic fatty acid and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Pfam: AhpC/TSA family no TMHs. No signal peptide.; Family membership
YP_934168.1	Conserved hypothetical protein. Homology to TdenA01001041 of Thiobacillus denitrificans of 39% (gi|52007163|ref|ZP_00334541.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs
YP_934169.1	Hypothetical secreted protein. No homology of the entire protein to the data bank. no domains predicted signal peptide no TMHs
YP_934170.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
YP_934171.1	Putative transcriptional repressor,; High confidence in function and specificity
YP_934172.1	Probable glycerol trinitrate reductase. Homology to nerA of A. radiobacter of 66% (trembl|O31246) InterPro: NADH:flavin oxidoreductase/NADH oxidase (IPR001155) Pfam: NADH:flavin oxidoreductase/NADH oxidase no signal peptide no TMHs; High confidence in function and specificity
YP_934173.1	Conserved hypothetical cytochrome c family protein. Homology to bra0353 of B. suis of 50% (trembl|Q8FWU2). InterPro: Cytochrome c class I (IPR003088). Pfam: cytochrome c. signal peptide. no TMHS; Function unclear
YP_934174.1	Conserved hypothetical secreted protein. Homology to gsu0710 of G. sulfurreducens of 66% (tremblnew|AAR34040). no doamins predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_934175.1	Transcriptional regulatory protein,; Specificity unclear
YP_934176.1	Conserved hypothetical sensor histidine kinase,MODULATES THE ACTIVITY OF FIXJ A TRANSCRIPTIONAL ACTIVATOR OF NITROGEN FIXATION FIXK GENE. FIXL PROBABLY ACTS AS A KINASE THAT PHOSPHORYLATES FIXJ.; Specificity unclear
YP_934177.1	Hypothetical protein,69% Identity (75% similarity) to TrEMBl;Q8XS84 Has PF06983, 3-demethylubiquinone-9 3-methyltransferase;IPR009725 3-dmu-93-mtfrase;This family represents a conserved region approximately 100 residues long within a number of bacterial and archaeal 3-demethylubiquinone-9 3-methyltransferases (EC:2.1.1.64). Note that some family members contain more than one copy of this region, and that many members are hypothetical proteins.; Function unclear
YP_934178.1	Conserved hypothetical membrane protein. Homology to Bcep02002160 of Burkholderia fungorum of 35% (gi|48787369|ref|ZP_00283451.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. 6 TMHs; Conserved hypothetical protein
YP_934179.1	catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis
YP_934180.1	Similar to TREMBL:Q82SX7 (48% identity, 66% similarity, generic methyl transferase). Pfam (PF01209): ubiE/COQ5 methyltransferase family. TIGRFAM (TIGR00091): conserved hypothetical protein. TMHMM reporting one transmembrane helix.; Function unclear
YP_934181.1	Conserved hypothetical membrane protein. Homology to NE2170 of Nitrosomonas europaea of 44% (trembl|Q82SX6(SRS)). Pfam: GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. no signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934183.1	InterPro: Bacterial transferase hexapeptide repeat; Function unclear
YP_934184.1	Bactoprenol glucosyl transferase (EC 2.4.1.-). Involved in O antigen modification. Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (By similarity).; Specificity unclear
YP_934185.1	High confidence in function and specificity
YP_934186.1	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs
YP_934187.1	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs
YP_934188.1	putative prophage integrase; Family membership
YP_934189.1	GGDEF/EAL/PAS-domain containing protein
YP_934190.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide present. TMH in signal peptide.
YP_934191.1	Putative periplasmic protein [creA],59% identity (77% similarity) to SwissProt;P08367. TrEMBL; Q8XZD0(59% identity). Has PF05981, CreA protein;IPR010292, CreA: This family consists of several bacterial CreA proteins, the function of which is unknown.; High confidence in function and specificity
YP_934192.1	Conserved hypothetical protein. Homology to Daro03001159 of Dechloromonas aromatica of 50% (gi|41726181|ref|ZP_00152939.1|(NBCI ENTREZ)). Pfam: ProQ activator of osmoprotectant transpoter ProP. This family includes ProQ, which is required for full activation of the osmoprotectant transporter ProQ, in Escherichia coli. no signal. peptide no TMHs
YP_934193.1	Conserved hypothetical protein. Homology to ebA7139 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA7139(KEGG)). No domains predicted. No signal peptide. No TMH present.
YP_934194.1	GGDEF family protein,; Conserved hypothetical protein
YP_934195.1	GGDEF family protein
YP_934196.1	Flagellin. Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. InterPro: Flagellin N-terminus, Flagellin C-terminus Pfam: Bacterial flagellin N-terminus, bacterial flagellin C-terminus no signal peptide no TMH; High confidence in function and specificity
YP_934197.1	InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear
YP_934198.1	Conserved hypothetical protein. Homology to BF2580 of Bacteroides fragilis of 47% (gnl|keqq|bfr:BF2580(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_934199.1	Conserved hypothetical protein. Homology to Mmc102000919 of Magnetococcus sp. MC-1 of 48% (gi|48833619|ref|ZP_00290637.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_934200.1	Hypothetical protein. No homology of the entire protein with the data base. InterPro: Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids. No signal peptide. No TMHs
YP_934201.1	Phosphoenolpyruvate phosphomutase precursor(Phosphoenolpyruvate mutase) (PEP mutase) (PEP phosphomutase).FORMATION OF A CARBON-PHOSPHORUS BOND BY CONVERTING PHOSPHOENOLPYRUVATE (PEP) TO PHOSPHONOPYRUVATE (P-PYR). 34% Isocit_lyase_ph.; High confidence in function and specificity
YP_934202.1	3-phosphonopyruvate decarboxylase (EC 4.1.1.-). InterPro: Thiamine pyrophosphate dependent enzyme acolac_lg: acetolactate synthase large subunit,biosynthetic type; Family membership
YP_934203.1	Conserved hypothetical alcohol dehydrogenase. Homology to bp2820 of B. pertussis of 29% (TREMBL:Q7VV69). InterPro: Iron-containing alcohol dehydrogenase (IPR001670). Pfam: Iron-containing alcohol dehydrogenase. no signal peptide. no TMHs.; Family membership
YP_934204.1	Putative CDP-glycerol:glycerophosphate glycerophosphotransferase tarF (EC 2.7.8.-). Catalyzes the addition of a second single glycerol-P residue to the prenolpyrophosphate-linked dissacharide to complete the linkage unit (Potential). PurN: phosphoribosylglycinamide formy; Family membership
YP_934205.1	InterPro: Glycosyl transferase family 2; Family membership
YP_934206.1	Conserved hypothetical protein. Homology to magn028431 of M. magnetotacticum of 33% (ZP 00053827). Domain structur: 76 aa - 144 aa TPR; 201 aa - 316 aa TPR; 408 aa - 761 aa COG3914. InterPro: TPR repeat (IPR001440). no signal peptide no TMH.
YP_934207.1	Flagellin. Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. InterPro: Flagellin N-terminus, Flagellin C-terminus Pfam: Bacterial flagellin N-terminus, bacterial flagellin C-terminus no TMH no signal peptide; High confidence in function and specificity
YP_934208.1	Protein flaG. Although these proteins are known to be important for flagellar their exact function is unknown TREMBL:Q82UA2: 56% identity, 79% similarity. InterPro:IPR005186; FlaG. Pfam:PF03646; FlaG L12: ribosomal protein L7/L12 Nonsecretory protein with low signal peptide probability (0.041): SignalP predicted Transmembrane helices 0; High confidence in function and specificity
YP_934209.1	Flagellar hook-associated protein 2 (HAP2) (Filament cap protein) (Flagellar cap protein). The flagellar hook-associated protein 2 (AHP2 or FilD) is a capping protein for the flagella and forms the distal end of the flagella. The protein plays a role in mucin specific adhesion of the bacteria. InterPro: Flagellar hook-associated protein 2 no signal-peptide no TMHs; High confidence in function and specificity
YP_934210.1	Flagellar protein fliS. The function of this protein in flagellar biosynthesis is unknown, but appears to be regulatory. Might be a chaperon for Flic. InterPro: Flagellar protein FliS fliS: flagellar protein FliS Pfam: Flagellar protein FliS no signal peptide no TMHs; Family membership
YP_934211.1	Hypothetical lagellar related protein FliT. Homology to fliT of R. solanacearum of 27% (trembl|Q8XST2). no domains predicted. no signal peptide. no TMHs.
YP_934212.1	Hypothetical protein,42% similarity with TrEMBL;Q82T52. No Signal Peptide or TMH reported present.; Family membership
YP_934213.1	Conserved hypothetical flagellar related protein. Homology to NE2078 of Nitrosomonas europaea of 48% (CAD85989). Tirgfam: flhB_rel(TIGR). This group describes a short protein (80-93 residues) homologous to the C-terminus of the flagellar biosynthetic protein FlhB. It is found so far only in species that also have FlhB. In a phylogenetic tree based on alignment of both this family and the homologous region of FlhB and its homologs, the members of this family form a monophyletic set. No TMHs. No signal peptide.; Conserved hypothetical protein
YP_934214.1	Conserved hypothetical protein,55% similarity to TrEMBL;Q82T50. Has IPR009926;PF07317:YcgR protein;This family consists of several hypothetical YcgR proteins. YcgR may be involved in the flagellar motor function and may be a new member of the flagellar regulon. No signal peptide or TMH reported present.; Function unclear
YP_934215.1	GGDEF/PAS/PAC-domain containing protein,; Conserved hypothetical protein
YP_934216.1	Region start changed from 2997519 to 2997495 (-24 bases)
YP_934217.1	Sigma-54 dependent response regulator,; High confidence in function and specificity
YP_934218.1	Putative sensory box sensor histidine kinase,; High confidence in function and specificity
YP_934219.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_934220.1	Flagellar motor switch protein fliG. FLIG IS ONE OF THREE PROTEINS (FLIG FLIN FLIM) THAT FORM A SWITCH COMPLEX THAT IS PROPOSED TO BE LOCATED AT THE BASE OF THE BASAL BODY. THIS COMPLEX INTERACTS WITH THE CHEY AND CHEZ CHEMOTAXIS PROTEINS IN ADDITION TO CONTACTING COMPONENTS OF THE MOTOR THAT DETERMINE THE DIRECTION OF FLAGELLAR ROTATION (BY SIMILARITY). fliG: flagellar motor switch protein Pfam: fliG C-terminal domain no signal peptide no TMHs; High confidence in function and specificity
YP_934221.1	Probable Flagellar assembly protein FliH, 38% identity to TrEMBL;Q7VYE7, Q7WJB3, Q8XSS5. Has PF02108,Flagellar assembly protein FliH;IPR000563, Flag_FliH; Many flagellar proteins are exported by a flagellum-specific export pathway. Attempts have been made to characterise the apparatus responsible for this process, by designing assays to screen for mutants with export defects. Experiments involving filament removal from temperature-sensitive flagellar mutants of Salmonella typhimurium have shown that, while most mutants were able to regrow filaments, flhA, fliH, fliI and fliN mutants showed no or greatly reduced regrowth. This suggests that the corresponding gene products are involved in the process of flagellum-specific export. The sequence of fliH has been deduced and shown to encode a protein of molecular mass of 25,782 Da.
YP_934222.1	ATP synthase (EC 3.6.3.14). Probable catalytic subunit of a protein translocase for flagellum-specific export or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage. InterPro: ATP synthase alpha and beta subunit central region Pfam: ATP synthase alpha/beta family no signal peptide no TMHs; High confidence in function and specificity
YP_934223.1	Flagellar fliJ protein. FLAGELLAR PROTEIN THAT AFFECTS CHEMOTACTIC EVENTS. Might have a chaperon-like activity InterPro: Flagellar FliJ protein no signal peptide no TMHs; Family membership
YP_934224.1	Flagellar hook-length control protein. Controls the length of the flagellar hook. no TMHs no signal peptide; Family membership
YP_934225.1	putative flagellar basal body-associated protein FliL Controls the rotational direction of flagella during chemotaxis. no signal peptide no TMHs; Family membership
YP_934226.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
YP_934227.1	Flagellar motor switch protein fliN (Flagellar motor switch protein mopA) (Fragment). FliN is one of three proteins (FliG FliN FliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins in addition to contacting components of the motor that determine the dirction of flagellar rotation (by similarity). InterPro: Surface presentation of antigens (SPOA) protein, Flagellar motor switch FliN protein Pfam: Surface presentation of antigens (SPOA) protein no signal peptide no TMHs; High confidence in function and specificity
YP_934228.1	Flagellar biosynthesis protein,FliO, 26% identity to TrEMBL;Q8XBA2, Q83ML3. SProt;P22586 Has Signal peptide. Has PF04347, Flagellar biosynthesis protein,FliO;IPR007442 ; FliO is an essential component of the flagellum-specific protein export apparatus. It is an integral membrane protein. Its precise molecular function is unknown.
YP_934229.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_934230.1	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus
YP_934231.1	Flagellar biosynthesis protein fliR. Role in flagellar biosynthesis. InterPro: Bacterial export protein family 1 PFam: Bacterial export proteins, family 1 no signal peptide most probable 8 TMHs; High confidence in function and specificity
YP_934232.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted signal peptide no TMHs
YP_934233.1	Flagellar hook-associated protein 3 (HAP3) (Hook-filament junction protein). no signal peptide no TMHs; High confidence in function and specificity
YP_934234.1	flagellar hook-filament junction protein 1 (HAP1). no signal peptide no TMHs; High confidence in function and specificity
YP_934235.1	Peptidoglycan hydrolase flgJ (EC 3.2.1.-) (Muramidase flgJ). Flagellum-specific muramidase which hydrolyses the peptidoglycan layer to assemble the rod structure in the periplasmic space (by similarity). InterPro: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidases Pfam: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidases no signal peptide no TMHs; High confidence in function and specificity
YP_934236.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum
YP_934237.1	Flagellar L-ring protein precursor (Basal body L-ring protein). Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. The L ring reside in the outer membrane. FlgH, which is exported across the cell membrane to their destinations in the outer membrane, has a typical N-terminal cleaved signal-peptide sequences and is predicted to have an extensive -sheet structure, in keeping with other outer membrane proteins. Pfam: Flagellar L-ring protein signal peptide no TMHs; High confidence in function and specificity
YP_934238.1	makes up the distal portion of the flagellar basal body rod
YP_934239.1	Flagellar basal-body rod protein flgF (Putative proximal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity
YP_934240.1	Flagellar hook protein flgE. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity
YP_934241.1	Basal-body rod modification protein flgD. FlgD is known to be absolutely required for hook assembly, yet it has not been detected in the mature flagellum. It appears to act as a hook-capping protein to enable assembly of hook protein subunits. no signal peptide no TMHs; Family membership
YP_934242.1	Flagellar basal-body rod protein flgC. The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity
YP_934243.1	Flagellar basal-body rod protein flgB (Putative proximal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. no signal peptide no TMHs; High confidence in function and specificity
YP_934244.1	Flagella basal body P-ring formation protein flgA precursor. Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a chaperon protein for the P-ring assembly (by similarity). signal peptide no TMHs; High confidence in function and specificity
YP_934245.1	Region start changed from 3024385 to 3024358 (27 bases)
YP_934246.1	Putative chaperon of flagella synthesis. FlgN is an export chaperon of FlgM and FlgK involved in flagellar synthesis. no signal peptide no TMHs; Family membership
YP_934247.1	Hypothetical secreted protein. Homology to cv0285 of C. violaceum of 25% (trembl|Q7P1C8) no domains predicted signal peptide TMH in signal peptide
YP_934248.1	Probable DNA-binding response regulator, ITS CARBOXYL-TERMINAL MOIETY MEDIATES THE MULTIMERIZATION OF THE OMPR PROTEIN. AS A MULTIMER IT TURNS ON THE EXPRESSION OF THE OMPC GENE; AS A MONOMER IT TURNS ON THE EXPRESSION OF THE OMPF GENE.; High confidence in function and specificity
YP_934249.1	Putative sensor histidine kinase,; High confidence in function and specificity
YP_934250.1	Conserved hypothetical protein. Homology to ebA6852 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA6852(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_934251.1	Putative sensory box histidine kinase, very low similarity to TREMBL: trembl|Q9FD00 (12% Erwinia stewartii, HrpX) InterPro: IPR005467 His_kinase. IPR003661 His_kinA_N. IPR000014 PAS_domain. IPR001610 PAC Pfam: PF02518 HATPase_c. PF00989 PAS. PF00785 PAC. TIGRFAM:TIGR00229 PAS domain S-box.; Function unclear
YP_934252.1	Probable transcriptional regulator, LuxR family,; Specificity unclear
YP_934253.1	Putative glycerol-3-phosphate dehydrogenase. Homology to glpA of B. hermsir of 38% (trembl|Q84I21) FAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the conversion of glycerol-3-phosphate into dihydroxyacetone phosphate: sn-glycerol-3-phosphate + acceptor = glycerone phosphate + reduced acceptor. InterPro: D-amino acid oxidase (IPR000927) Pfam: FAD dependent oxidoreductase no signal peptide no TMHs gidA: glucose-inhibited division prot; Family membership
YP_934254.1	Probable glycerol kinase. Homology to glpK of T. aquaticus of 53% (sprot|GLPK_THEAQ). Key enzyme in the regulation of glycerol uptake and metabolism. InterPro: Carbohydrate kinase FGGY family (IPR000577) Pfam: FGGY family of carobhydrates kinases, N-terminus; FGGY family of carobhydrates kinases, C-terminus no signal peptide no TMHs; High confidence in function and specificity
YP_934255.1	Conserved hypothetical membrane protein. Homology with CV1535 of C. violaceum of 46%. 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Intergral membrane protein DUF6. probable 9 TMHs. signal peptide; Conserved hypothetical protein
YP_934256.1	Conserved hypothetical protein. Homology to NE1501 of N.europaea of 47% (trembl:Q82UI4). No domains predicted. Signal peptide present. No TMH reported present.
YP_934257.1	SseA: putative thiosulfate sulfurtransferase (rhodanese-like protein) [EC:2.8.1.1]. This protein transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity (130-fold lower). Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity. Probable 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) (Rhodanese- like protein) (MST). InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity
YP_934258.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_934259.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_934260.1	Hypothetical metalloprotease yebA precursor (EC 3.4.24.-).; Specificity unclear
YP_934261.1	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors
YP_934262.1	forms a direct contact with the tRNA during translation
YP_934263.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_934264.1	Conserved hypothetical protein. Homology to rsc0489 of R. solanacearum of 73% (trembl|Q8Y247). no signal peptide. no TMH. No domains predicted.; Family membership
YP_934265.1	Probable Ubiquinone biosynthesis protein COQ7 homolog (Coenzyme Q biosynthesis protein 7 homolog) (Timing protein clk-1 homolog) (Fragment).; Function unclear
YP_934266.1	Conserved hypothetical secreted protein. Homology to ebA945 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA945(KEGG)). No domains predicted. Signal P reporting signal peptide present. No TMH present.; Conserved hypothetical protein
YP_934267.1	hydrolyzes diadenosine polyphosphate
YP_934268.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_934269.1	Probable Membrane-bound lytic murein transglycosylase C precursor (EC 3.2.1.-) (Murein hydrolase C).; Function unclear
YP_934270.1	Conserved hypothetical protein. Homology to Daro03000304 of Dechloromonas aromatica of 54% (gi|46140561|ref|ZP_00152132.2|(NBCI ENTREZ)). Has PF04519; Protein of unknown function, DUF583:This family contains several uncharacterised hypothetical proteins. No Signal peptide or TMH reported as present.
YP_934271.1	Putative two-component system sensor kinase,; Family membership
YP_934272.1	Conserved hypothetical secreted protein. Homology to ebA964 of Azoarcus sp. EbN1 of 33% (gnl|keqq|eba:ebA964(KEGG)). No domains predicted. Signal P reporting signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_934273.1	Putative two component transcriptional regulator,; Conserved hypothetical protein
YP_934275.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_934276.1	Conserved hypothetical secreted protein. Homology to ebA988 of Azoarcus sp. EbN1 of 43% (gnl|keqq|eba:ebA988(KEGG)). no domains predicted. signal peptie. no TMHs; Conserved hypothetical protein
YP_934277.1	Putative Nudix hydrolase ymfB (EC 3.6.-.-). mutt: mutator mutT protein; Specificity unclear
YP_934278.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_934279.1	Hypothetical protein , 47% identity to TrEMBL;Q7NW97,TrEMBL;Q7VTV4(56% identity). No domains,repeats, motifs or features present.; Function unclear
YP_934280.1	Conserved hypothetical protein. Homology to ne1289 of N. europaea of 49% (trembl|Q82V21). InterPro: Esterase/lipase/thioesterase family active site (IPR000379). no signal peptide. no TMH.
YP_934281.1	Phosphomannomutase/phosphoglucomutase (PMM / PGM). The phosphomannomutase activity produces a precursor for alginate polymerization. This enzyme participates in both the breakdown and synthesis of glucose.Catalytic activity: Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 58% PG/PMM_mutase.IPR005844; PG_PMM_ABAI.IPR005845; PG_PMM_ABAII.IPR005846; PG_PMM_ABAIII.IPR005843; PG_PMM_C. Pfam:PF02878; PGM_PMM_I; 1.PF02879; PGM_PMM_II; 1.PF02880; PGM_PMM_III. PF00408; PGM_PMM_IV; 1.; High confidence in function and specificity
YP_934282.1	Conserved hypothetical protein with unknown function. No domains predicted. Similarity to TREMBL: trembl|Q9I6D7 (33% Pseudomonas aeruginosa, hypothetical protein pa0356) / trembl|Q88CQ4 (30% Pseudomonas putida (strain KT2440), pp5126)
YP_934283.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_934284.1	Conserved hypothetical protein. Homology to ebA1022 of Azoarcus sp. EbN1 of 86% (gnl|keqq|eba:ebA1022(KEGG)). Has PF01923, Cobalamin adenosyltransferase;IPR002779,DUF80; This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation. The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12. No signal peptide or TMH present.
YP_934285.1	Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs.
YP_934286.1	Probable RNA-directed RNA polymerase (EC 2.7.7.48) (RNA replicase) (216.5 kDa protein) (ORF1). alkb: alkylated DNA repair protein AlkB.; Function unclear
YP_934287.1	Conserved hypothetical monoamine oxidase. Homology to rsp0431 of R. solanacearum of 34% (trembl|Q8XSN6). In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. InterPro: Amine oxidase (IPR002937). Pfam: Flavin containing amine oxidase. probable signal peptide. no TMH.; Family membership
YP_934288.1	Conserved hypothetical membrane protein. Homology to SC3D11.05C of Streptomyces coelicolor of 33% (trembl|Q9L1F7(SRS)). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting three transmembrane helices. No signal peptide.; Conserved hypothetical protein
YP_934289.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_934290.1	Conserved hypothetical RumC homolog. Homology to rumC of P.aeruginosa of 43% (gi|20139744|sp|Q9I4U3|RMUC_PSEAE). Pfam: RmuC family. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures. Signal peptide predicted. 2 TMHs.,; Conserved hypothetical protein
YP_934291.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_934292.1	Glutathione-regulated potassium-efflux system protein kefC (K(+)/H(+) antiporter). Transport system that facilitates potassium-efflux possibly by potassium-proton antiport.Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily. 23% K_eff.IPR006153; Na_H_porter. Pfam:PF00999; Na_H_Exchanger; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix:11; High confidence in function and specificity
YP_934293.1	in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ
YP_934294.1	Conserved hypothetical membrane protein. Homology to cv0790 of C. violaceum of 50% (tremble:Q7NZX9). Has PF05252, Uncharacterised protein family (UPF0191);IPR007916 ; This family of proteins is functionally uncharacterised. signal peptide. 5 TMHs; Conserved hypothetical protein
YP_934295.1	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis
YP_934296.1	Hypothetical protein yjgA, 46% identity(59% similarity) to SwissProt;Q8FAF3.SwissProt;Q83P53 Has PF04751, Protein of unknown function (DUF615);IPR006839;This family of bacterial proteins has no known function. NO Signal Peptide or TMH reported present.; Function unclear
YP_934297.1	Probable PmbA protein. Homology to pmbA of E. coli of 48% (sprot|PMBA_ECOLI). MAY FACILITATE THE SECRETION OF THE PEPTIDE ANTIBIOTIC MICROCIN B17 (MCCB17) BY COMPLETING ITS MATURATION. SUPPRESSES THE INHIBITORY ACTIVITY OF THE CARBON STORAGE REGULATOR (CSRA). Pfam: Putative modulator of DNA gyrase no signal peptide no TMHs; High confidence in function and specificity
YP_934298.1	Similar to TREMBL:Q8G2H7 (58% identity); TREMBL:Q8UK55 (57% identity); TREMBL:Q89NT9 (58% identity). SignalP reporting signal peptide.; Specificity unclear
YP_934299.1	Similar to TREMBL:Q7WQP2 (61% identity); TREMBL:Q7W1R6 (61% identity); TREMBL:Q8G2H8 (50% identity). TIGRFAM (TIGR00786): TRAP transporter DctM subunit. TMHMM predicting 14 transmembrane helices.; Specificity unclear
YP_934300.1	Similar to TREMBL:Q7WQP3 52% identity); TREMBL:Q92P73 (54% identity); TREMBL:Q8UK53 (48% identity). TMHMM reporting four transmembrane helices.; Specificity unclear
YP_934301.1	Probable phosphoglycerate mutase GpmB (phosphoglyceromutase) 0(Pgam). Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 31% PG/BPGM_mutase. Pfam:PF00300; PGAM; 1.; High confidence in function and specificity
YP_934302.1	Probable two component sensor protein,; High confidence in function and specificity
YP_934303.1	Transcriptional regulatory protein KdpE,; High confidence in function and specificity
YP_934304.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_934305.1	Transcriptional regulator,; Conserved hypothetical protein
YP_934306.1	Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]. CONVERTS 25-DIAMINO-6-(RIBOSYLAMINO)-4(3H)-PYRIMIDINONE 5-PHOSPHATE INTO 5-AMINO-6-(RIBOSYLAMINO)-24(1H3H)- PYRIMIDINEDIONE 5-PHOSPHATE. InterPro: Riboflavin biosynthesis protein RibD TIGRFAM: eubact_ribD: riboflavin biosynthesis protein; High confidence in function and specificity
YP_934307.1	Dinucleotide-utilizing enzyme involved in molybdopterin and/or thiamine biosynthesis Belongs to the hesA/moeB/thiF family, by similarity. TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity
YP_934308.1	Conserved hypothetical protein. Homlogy to ebA1048 Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebA1048(KEGG)). no domains predicted. no signal peptide. no TMHs
YP_934309.1	Carboxy-terminal processing protease precursor (EC 3.4.21.102) (C- terminal processing protease). prc: carboxyl-terminal protease; High confidence in function and specificity
YP_934310.1	Homology to peptidase, M23/M37 family InterPro: Peptidase family M23/M37
YP_934311.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_934312.1	Putative transcriptional activator, ArsR family,; High confidence in function and specificity
YP_934313.1	Similar to Rhodanese domain protein, a sulphurtransferase involved in cyanide detoxification. Hypothetical protein slr1261. InterPro: Rhodanese/cdc25 fold; Function unclear
YP_934314.1	Probable glutaredoxin. Homology to grx3 of E. coli. of 53% (SWISSPROT:GLR3_ECOLI). The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase. Pfam: Glutaredoxin Tigrfam: TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; High confidence in function and specificity
YP_934315.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
YP_934316.1	Conserved hypothetical secreted protein. Homology to CV1128 of Chromobacterium violaceum of 43% (trembl:Q7NYZ4). Has Signal Peptide. Has PF06347, Protein of unknown function (DUF1058);IPR010466 ;This family consists of several hypothetical bacterial proteins of unknown function. No TMHs; Conserved hypothetical protein
YP_934317.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_934318.1	Region start changed from 3095806 to 3095845 (39 bases)
YP_934319.1	Hypothetical protein yhgH. Members of PRT family are catalytic and regulatory proteins involved in nucleotide synthesis and salvage. The name PRT comes from phosphoribosyltransferase enzymes, which carry out phosphoryl transfer reactions on PRPP, an activated form of ribose-5-phosphate SPROT:P46846: 33% identity, 51% similarity InterPro; IPR000836; PRtransferase. Pfam; PF00156; Pribosyltran; 1 Absence of Signal peptide and Transmembrane helices PPR: pentatricopeptide repeat domain; High confidence in function and specificity
YP_934320.1	Biotin synthase (Biotin synthetase). catalytic activity: dethiobiotin + sulfur = biotin. cofactor: binds a 4fe-4s cluster coordinated with 3 cysteines and an exchangeable s-adenosyl-l-methionine, and a 2fe-2s cluster coordinated with 3 cysteines and 1 arginine. pathway: biotin biosynthesis; last step. similarity: belongs to the biotin and lipoic acid synthetases family. TIGRFAM: bioB: biotin synthetase; High confidence in function and specificity
YP_934321.1	FUNCTION:BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin. PATHWAY:Biotin biosynthesis. SIMILARITY:Belongs to the methyltransferase superfamily TREMBL:Q7NPW6 - 46% identity,61% similarity to Chromobacterium bioC. TREMBL:Q82SL9 InterPro (IPR000051): SAM (and some other nucleotide) binding motif. Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Family membership
YP_934322.1	TREMBL:Q7NQN9: 48% identity; 66% similarity SPROT:P53078: 28% identity, 47% similarity InterPro :IPR006402; HAD-SF-IA-v3. IPR005833: Hlgnase/hydrlase. IPR005834: Hydrolase. IPR010237; Pyr-5-nucltdase. Pfam PF00702; Hydrolase; 1. PRINTS PR00413; HADHALOGNASE. TIGRFAMs TIGR01509; HAD-SF-IA-v3; 1. TIGR01993; Pyr-5-nucltdase; SSM1 protein. No signal peptide. No transmembrane helices. Could be an enzyme that inactivates 6-azauracil by modifying it. InterPro: Haloacid dehalogenase/epoxide hydrolase family otsB: trehalose-phosphatase; Family membership
YP_934323.1	Putative acetyltransferase,42% identity to TrEMBL;Q7WFK1, Putative acetyltransferase [BB4270] [Bordetella bronchiseptica(Alcaligenes bronchisepticus)]. Has PF00583:IPR000182;Acetyltransferase (GNAT) family;This family contains proteins with N-acetyltransferase functions.Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of chromatin, histones tend to be hyperacetylated, whereas in transcriptionally silent regions histones are hypoacetylated. The histone acetyltransferases are divided into five families.
YP_934324.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_934325.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_934326.1	Probable cytochrome c4. Homology to cc4 of A. vinelandii of 42% (sprot|CYC4_AZOVI). Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems. Pfam: cytochrome C signal peptide no TMHs; High confidence in function and specificity
YP_934327.1	Hypothetical protein, 51% identity (59% similarity) to TrEMBL;Q8Y0B0. TrEMBL; Q7NWN1(53% identity). Has PF04305, Protein of unknown function (DUF455).IPR007402. Has no signal Peptide or TMH present.; Function unclear
YP_934328.1	Molybdopterin biosynthesis protein moeA. Involved in the biosynthesis of a demolybdo-cofactor (molybdopterin) necessary for molybdo-enzymes. Seems to be involved in a step of activation of molybdenum in the form of thiomolybdenum. InterPro: Molybdenum cofactor biosynthesis protein molyb_syn: molybdenum cofactor synthesis; High confidence in function and specificity
YP_934329.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
YP_934330.1	Phosphate transport system protein phoU. Probably involved in phosphate transport and metabolism. In P aeruginosa PhoU is involved in the regulation of alkaline phosphatase expression and in the induction of Pi taxis.; High confidence in function and specificity
YP_934331.1	Hpyothetical Protein, 69% identity (84% simialarity) to SwissProt; Q8Y010. Has PF04362, Protein of unknown function (DUF495);IPR007457;Methionine start codon is known to be cleaved from Escherichia coli protein YggX (P52065). YggX is also known to be highly abundant in E. coli K-12. No Signal peptide or TMH present.
YP_934332.1	GGDEF/PAS/PAC-domain containing protein
YP_934333.1	catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis
YP_934334.1	Hypothetical protein, 53% identity (69% similarity) to TrEMBL;Q7NQR2. TREMBL;Q74F81. Has 2 copies of PF03976,IPR005660, Domain of unknown function (DUF344);This presumed domain is found in one or two copies per protein. The domain is about 230 amino acids in length and has many conserved motifs that are probably functionally important. No Signal Peptide or TMH present.
YP_934335.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_934336.1	Inositol-1-monophosphatase(IMPase)(Inositol-1- phosphatase)(I-1-Pase).May act by enhancing the synthesis or degradation of phosphorylated messenger molecules. Catalytic activity: myo-inositol 1-phosphate + h(2)o = myo- inositol + phosphate. 36% Inositol_P. Pfam:PF00459; Inositol_P; 1.; High confidence in function and specificity
YP_934337.1	Hypothetical protein, has very weak homology with hits in the database. Has No domains, repeats, motifs or features could be predicted with confidence above threshold scores.
YP_934338.1	Probable phosphoribulokinase. Homology to prkB of r. sphaeroides of 59% (sprot|KPP2_RHOSH). Phosphoribulokinase catalyses the ATP-dependent phosphorylation of ribulose-5-phosphate to ribulose-1,5-phosphate, a key step in the pentose phosphate pathway where carbon dioxide is assimilated by autotrophic organisms. InterPro: Phosphoribulokinase family (IPR006082) Pfam: Phosphoribulokinase no signal peptide no TMHs; High confidence in function and specificity
YP_934339.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_934340.1	Glyceraldehyde-3-phosphate dehydrogenase(GAPDH)plays an important role in glycolysis and gluconeogenesis by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho- glycerate.61% GAPDH-I.IPR000173; GAP_dhdrogenase. Pfam:PF02800; Gp_dh_C; 1.PF00044; Gp_dh_N; 1. TIGRFAMs:TIGR01534; GAPDH-I; 1.; High confidence in function and specificity
YP_934341.1	Conserved hypothetical secreted protein. Homology to xcc3191 of X. campestris of 41% (trembl|Q8P5Z1). no domains predicted. signal peptide. no TMHs.; Function unclear
YP_934342.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_934343.1	Hypothetical secreted protein. No good homology to the data bank. No domains predicted. Signal peptide reported to be present. No TMH reported present. ssl1: transcription factor ssl1
YP_934344.1	Conserved hypothetical membrane protein. Homology to an orf of the uncultured bacterium 463 of 33% (tremblnew|AAS07979). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_934345.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_934346.1	class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis
YP_934347.1	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 73% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present.; High confidence in function and specificity
YP_934348.1	Conserved hypothetical secreted protein. Homology to qbdB of Pseudomonas putida of 56% (gi|22779360|dbj|BAC15558.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.,; Conserved hypothetical protein
YP_934349.1	Similar to TREMBL:Q9F9U3 (44% identity); TREMBL:Q88H93 (39% identity); SWISSPROT:P28614 (35% identity). InterPro (IPR002078): Sigma-54 factor interaction domain. InterPro (IPR002197): Helix-turn-helix, Fis-type. InterPro (IPR003593): AAA ATPase. Pfam (PF02954): Bacterial regulatory protein, Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_934350.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934351.1	Putative AIG2-like protein. Homology to AIG2 of a. thaliana of 27% (sprot|AIG2_ARATH) AIG2 is an Arabidopsis proteins that exhibit RPS2- and avrRpt2-dependent induction early after infection with Pseudomonas syringae pv maculicola strain ES4326 carrying avrRpt2. Pfam: AIG2-like family singal peptide no TMHs
YP_934352.1	Conserved hypothetical membrane protein. Homology to AQ_563 of Aquifex aeolicus of 37% (trembl|O66835(SRS)). Has IPR003660;PF00672;HAMP domain:This domain is known as the HAMP domain for histidine kinases, adenylyl cyclases,methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160(GGDEF)domain,this domain is found linked to a wide range of non-homologous domains in a variety of bacteria. The function of this domain is unknown, however it has been shown to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. TMHMM reporting 1 TMH present. Signal peptide present.; Conserved hypothetical protein
YP_934353.1	Proline/betaine transporter (Proline porter II) (PPII). STRETCH-INACTIVATED PROLINE/BETAINE TRANSPORTER. PROP IS BOTH AN OSMOSENSOR AND AN OSMOREGULATOR WHICH IS AVAILABLE TO PARTICIPATE EARLY IN THE BACTERIAL OSMOREGULATORY RESPONSE. MEDIATES THE ACTIVE ACCUMULATION OF SOLUTES SUCH AS PROLINE GLYCINE BETAINE STACHYDRINE PIPECOLIC ACID ECTOINE AND TAURINE.PROBABLE MtbA PROTEIN 2A0106: citrate-proton symport; Specificity unclear
YP_934354.1	Conserved hypothetical glycerophosphoryl diester phosphodiesterase. Homology to TdenA01001091 of Thiobacillus denitrificans of 66% (gnl|keqq|mca:MCA1922(KEGG)).InterPro: Glycerophosphoryl diester phosphodiesterase (IPR004129). Pfam: Glycerophosphoryl diester phosphodiesterase. signal peptide. no TMHs
YP_934355.1	Probable aldehyde dehydrogenase (NAD+). Homology to cddD of R. ruber SC1 of 59% (trembl|Q938F1) Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. Pfam: Aldehyde dehydrogenase family no TMHs no signal peptide; Family membership
YP_934356.1	Conserved hypothetical secreted protein. Homology to PA3284 of Pseudomonas aeruginosa of 40% (trembl|Q9HYV9(SRS)). No domains predicted. Signal peptide present. No TMH Present.; Conserved hypothetical protein
YP_934357.1	Conserved hypothetical protein. Homology to PA3283 of P.aeruginosa of 54% (trembl:Q9HYW0). Has PF05114,Protein of unknown function (DUF692);IPR007801:This family consists of several uncharacterised bacterial proteins. No signal peptide or TMH present.
YP_934358.1	Conserved hypothetical protein. Homology to PP2399 of P.putida of 36% (trembl:Q88K92). No domains predicted. No TMHs. No signal peptide.
YP_934359.1	Conserved hypothetical membrane protein. Homology to PA4104 of Pseudomonas aeruginosa of 46% (trembl|Q9HWS4(SRS)). No domains predictec. no signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934360.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_934361.1	Conserved hypothetical protein. Homology to CV2972 of C.violaceum of 51% (trembl:Q7NTT1). No domains predicted. No TMHs. No signal peptide.
YP_934362.1	Probable carboxylesterase. Homology to estB of P. flourescens of 41% (sprot|EST2_PSEFL). Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity. InterPro: Phospholipase/Carboxylesterase(IPR003140); Esterase/lipase/ thioesterase family acitve site (IPR000379) Pfam: Phospolipase/Carboxylesterase no signal peptide no TMHs; High confidence in function and specificity
YP_934363.1	Conserved hypothetical membrane protein. Homology to PJS6w01004232 of Polaromonas sp. JS666 of 53% (gi|54028976|ref|ZP_00361120.1|(NBCI ENTREZ)). InterPro:IPR002035; VWF_A. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA; 1. PROSITE:PS50234; VWFA; MIP: MIP family channel proteins. No signal peptide present. No. of TMH's: 3 (TMHMM predicted).; Conserved hypothetical protein
YP_934364.1	Hypothetical protein Rv1480/MT1527/Mb1516. TREMBL:Q7MUE8: 33% identity, 52% similarity. This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterPro: IPR002881; DUF58. Pfam: PF01882; DUF58 Absence of transmembrane helices (TMHMM predicted) cmk: cytidylate kinase; Specificity unclear
YP_934365.1	MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBLnew:CAE55395: 54% identity, 71% similarity InterPro:IPR003593; AAA_ATPase. IPR000523; Mg_chelatse_chII. Pfam PF01078; Mg_chelatase; 1. SMART SM00382; AAA; 1 InterPro IPR003593; AAA_ATPas ruvB: Holliday junction DNA helicase Ru; High confidence in function and specificity
YP_934366.1	Conserved hypothetical serine protease. Homology to PJS6w01004229 of Polaromonas sp. JS666 of 53% (gi|54028973|ref|ZP_00361117.1|(NBCI ENTREZ)). Interpro: HtrA/DegQ protease family (IPR001940); Serine protease,trypsine family (IPR001254). Pfam: Typsin. probable signal peptide. no TMHs; Conserved hypothetical protein
YP_934367.1	Conserved hypothetical membrane protein. TREMBL:Q9CBL9: 33% identity; 52% similarity The von Willebrand factor is a large multimeric glycoprotein found in bloodplasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily Hypothetical protein MAV335. InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA 2_A_01_02: Multidrug resistance protein Presence of Signal peptide (SignalP predicted) Presence of 3 transmembrane helices (TMHMM predicted).; Conserved hypothetical protein
YP_934368.1	Conserved hypothetical protein. Homology to CE0355 of C.efficiens of 56% (trembl:Q8FSM8). No domains predicted. No THs. No signal peptide.
YP_934369.1	GGDEF/PAS/PAC-domain containing protein
YP_934370.1	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 44% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear
YP_934371.1	Putative cytoplasmic protein ygiD, 35% identity to TrEMBL;Q8ZLZ3. TrEMBL;Q8XBP3,Q83JK6. Has PF02900,Catalytic LigB subunit of aromatic ring-opening dioxygenase;IPR004183:The LigAB enzyme (a protocatechuate 4,5-dioxygenase), of Sphingomonas paucimobilis oxidizes protocatechuate (or 3,4-dihydroxybenzoic acid, PCA). The enzyme belongs to the class III extradiol-type catecholic dioxygenase family, which catalyzes the ring-opening reaction of protocatechuate and related compounds.; Conserved hypothetical protein
YP_934372.1	Conserved hypothetical cytochrome B561. Homology to cv3278 of C. violaceum of 69% (trembl|Q7NSZ1). Involved in electronen transport. no domains reported. no signal peptide. 4 TMHs; Family membership
YP_934373.1	Conserved hypothetical YceI like protein. Homology to CV3277 of C.violaceum of 51% (tremble:Q7NSZ2). Has PF04264, YceI like family;(IPR007372): E. coli YceI is a base-induced periplasmic protein. Its function has not yet been characterised. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_934374.1	Conserved hypothetical YceI like protein. Homology to cv3276 of C. violaceum of 69% (trembl|Q7NSZ3(SRS)) Pfam: YceI like family E. coli. YceI is a base-induced periplasmic protein. Its function has not yet been characterised. signal peptide. no TMHs; Family membership
YP_934375.1	Conserved hypothetical membrane protein. Homology to NE1887 of Nitrosomonas europaea of 39% (trembl|Q82TK0). No domains predicted. No signal peptide. TMHMM2 program predicts presence of 1 TMH's.; Conserved hypothetical protein
YP_934376.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_934377.1	Conserved hypothetical protein. Homology to AGR_C_1551 of A.tumefaciens of 40% (trembl:Q7D0J2). No domains predicted. No TMHs. No signal peptide.
YP_934378.1	Conserved hypothetical protein, 67% similarity to TrEMBL:Q8UH3. No good homology with hits in the DB particularly at the start. Signal peptide reported present. No TMH present.; Family membership
YP_934379.1	Conserved hypothetical membrane protein. Homology to cv3790 of C. violaceum of 36% (cvi:CV3790(KEGG). no domains predicted. no signal peptide. 6 TMHs.; Conserved hypothetical protein
YP_934380.1	Oligopeptidase A counts to the Thimet oligopeptidase family which cleave medium sized peptides. Similar to trembl|Q7VZC9 (49%), to trembl|Q9JX57 (48%) and to sprot|OPDA_ECOLI (51%). Pfam (PF01432): Peptidase family M3; Specificity unclear
YP_934381.1	Low similiraty to glutaredoxin protein Grx. Has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase.Reduces low molecular weight disulfides and proteins (by similarity). Hypothetical protein yjbD. Signal peptide; Function unclear
YP_934382.1	Putative ammonium transporter with sensory/GGDEF boxes. TREMBL:Q88M14: 50% identity; 65% similarity; TREMBL:Q7UK31: 46% identity; 58% siilarity InterPro:IPR001633; EAL. IPR000160; GGDEF. IPR001610; PAC. IPR000014; PAS_domain. IPR001905; Ammonium_transpt. IPR003594; ATPbind_ATPase Pfam: PF00563; EAL; PF00990; GGDEF; PF00785; PAC; PF00989; PAS; PF00909; Ammonium_transp SMART SM00267; DUF1; SM00052; DUF2; SM00086; PAC; SM00091; PAS amt: ammonium transporter Nonsecretory protein with signal peptide (SignalP predicted). Presence of 12 transmembrane helices (TMHMM predicted).; Specificity unclear
YP_934383.1	Region start changed from 3161811 to 3162171 (-360 bases)
YP_934384.1	Hypothetical protein, has weak homology with other hits in the Database. TrEMBL;Q67LU3(34%). Has Signal Peptide.
YP_934385.1	Putative transcription regulator, Nnr-type.; Family membership
YP_934386.1	Conserved hypothetical secreted protein. Homology to RPA1091 of R.palustris of 57% (tremble:CAE26534). No domains predicted. No TMH. signal peptide present.; Conserved hypothetical protein
YP_934387.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_934388.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
YP_934389.1	Putative peptidyl-prolyl cis-trans isomerase. Homology to surA of E. coli of 32% (sprot|SURA_ECOLI). Assist in the folding of extracytoplasmic proteins. Essential for the survival of E.coli in stationary phase. Pfam: PPIC-type PPIASE domain signal peptide no TMHs; Family membership
YP_934390.1	Organic solvent tolerance protein precursor.; High confidence in function and specificity
YP_934391.1	Conserved hypothetical protein. Homology to ne0191 of N. europaea of 61% (trembl|Q82XR3). Pfam: DUF227. no signal peptide. no TMHs.
YP_934392.1	Specificity unclear
YP_934393.1	Xaa-Pro aminopeptidase,; Specificity unclear
YP_934394.1	ubiH; aromatic-ring hydroxylase (flavoprotein monooxygenase) Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone. Ubiquinone biosynthesis pathway, by similarity.; High confidence in function and specificity
YP_934395.1	Conserved hypothetical tRNA-dihydrouridine synthase. Homology to dusB of Azoarcus sp. EbN1 of 81% (gnl|keqq|eba:ebA1152(KEGG)). Pfam: Dihydrouridine synthase (Dus). Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archae. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA. It is likely that different family members have different substrate specificities, which may overlap. Dus 1 (Q9HGN6) from Saccharomyces cerevisiae acts on pre-tRNA-Phe, while Dus 2 (P53720) acts on pre-tRNA-Tyr and pre-tRNA-Leu. Dus 1 is active as a single subunit, requiring NADPH or NADH, and is stimulated by the presence of FAD. Some family members may be targeted to the mitochondria and even have a role in mitochondria. No signal peptide. No TMHs; Conserved hypothetical protein
YP_934396.1	Putative fis-like DNA-binding protein, 57% Identity to SwissProt;Q8Y231,TrEMBL;Q7P0M2(58% Identity). Has PF02954, Bacterial regulatory protein, Fis family;IPR002197 HTH_Fis; The Factor for Inversion Stimulation (FIS) protein is a regulator of bacterial functions, and binds specifically to weakly related DNA sequences. It activates ribosomal RNA transcription, and is involved in upstream activation of rRNA promoters. The protein has been shown to play a role in the regulation of virulence factors in both Salmonella typhimurium and Escherichia coli. Some of its functions include inhibition of the initiation of DNA replication from the OriC site,and promotion of Hin-mediated DNA inversion.
YP_934397.1	involved in de novo purine biosynthesis
YP_934398.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_934399.1	catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis
YP_934400.1	Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present. HIGH-AFFINITY H+/SULFATE COTRANSPORTER THAT MEDIATES THE UPTAKE OF SULFATE BY PLANT ROOTS FROM LOW CONCENTRATIONS OF SULFATE IN THE SOIL SOLUTION.; High confidence in function and specificity
YP_934401.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_934402.1	Conserved hypothetical 16S rRNA processing protein rimM. Homology to rimM of R. solanacearum of 44% (sprot|RIMM_RALSO). Essential for efficient processing of 16S rRNA. Probably part of the 30S subunit prior to or during the final step in the processing of 16S free 30S ribosomal subunits. It could be some accessory protein needed for efficient assembly of the 30S subunit. It is needed in a step prior to rbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes. Pfam: RimM. no signal peptide. no TMHs; High confidence in function and specificity
YP_934403.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_934404.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_934405.1	TREMBL:Q8XWQ6: 39% identity, 56% similarity Hypothetical protein HI1703. InterPro: IPR005495; YjgP_YjgQ. Pfam: PF03739;Pfam :DUF214:Predicted permease Members of this family are predicted integral membrane proteins of unknown function. They are about 350 amino acids long, contain about 6 transmembrane regions and may be permeases, although there is no verification of this. subcellular location:integral membrane protein (potential). similarity:strong, to h.influenzae hi1703 2a69: Auxin Efflux Carrier TMHMM predicted 6 transmembrane helices; Conserved hypothetical protein
YP_934406.1	Conserved hypothetical membrane protein. TREMBL:Q8XWQ7: 40% identity; 55% similarity: probable integral membrane protein InterPro:IPR005495; YjgP_YjgQ. Pfam:PF03739; YjgP_YjgQ :UbiA : UbiA prenyltransferase family Pfam:DUF112:Integral membrane protein DUF112 Signal peptide present (Signal P predicted). Transmembrane helices: 5 (TMHMM predicted).; Conserved hypothetical protein
YP_934407.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_934408.1	Putative DNA polymerase III chi subunit, 40% Identity to TrEMBL; Q8XWQ9,Q63WC2,Q62LH1. Has PF04364, DNA polymerase III chi subunit, HolC;IPR007459, DNA_pol3_chi; The DNA polymerase III holoenzyme is the polymerase responsible for the replication of the Escherichia coli chromosome. The holoenzyme is composed of the DNA polymerase III core, the sliding clamp, and the DnaX clamp loading complex. The DnaX complex contains either either the tau or gamma product of gene dnax, complexed to delta.delta' and to chi psi. Chi forms a 1:1 heterodimer with psi. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' allowing a functional clamp-loading complex to form at physiological subunit concentrations. Psi is responsible for the interaction with DnaX (gamma/tau), but psi is insoluble unless it is in a complex with chi.
YP_934409.1	Conserved hypothetical protein. Homology to ebA7176 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA7176(KEGG)). no domains predicted. no signal peptide. no TMHs
YP_934410.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_934411.1	Putative TetR family transcriptional regulator,; Family membership
YP_934412.1	Similar to TREMBL:Q82VH0 (64% identity); TREMBL:Q9HTW0 (63% identity); TREMBL:Q8FZX1 (64% identity). TMHMM predicting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear
YP_934413.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transporter. TMHMM predicting five transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; High confidence in function and specificity
YP_934414.1	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q8ZLD9 (56% identity); TREMBL:Q8VR08 (56% identity). Pfam (PF00529): HlyD family secretion protein. SignalP reporting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership
YP_934415.1	Probable outer membrane efflux protein. Homology to oprM of P. aeruginosa of 47%. Component of an efflux system that confers multidrug or multible antibiotic resistence. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Family membership
YP_934416.1	In P. aeruginosa fimT and fimU genes contain prepilin-like leader sequences. FimT plays probable a role in fimbrial biogenesis. Similar to trembl|Q87FA9 (30%). Pfam (PF00114): Pilin (bacterial filament) TMHMM reporting one TMH. SignalP reporting Signal peptide.; Function unclear
YP_934417.1	In P. aeruginosa the genes pilV and pilE encode prepilin-like proteins involved in type 4 fimbrial biogenesis. Similar to trembl|Q8PJ74 (46%). SignalP reporting Signal Peptide.; Function unclear
YP_934418.1	Conserved hypothetical protein
YP_934419.1	In P. aeruginosa the PilW and PilX proteins are membrane located, possess the hydrophobic N-terminus characteristic of prepilin-like proteins, and appear to belong to the GspJ and GspK group of proteins that are required for protein secretion in a wide range of Gram-negative bacteria. These genes are involved in the assembly of type 4 fimbriae. Similar to trembl|Q8PJ76 (34%). TMHMM reporting one TMH. SignalP reporting Signal peptide.; Function unclear
YP_934420.1	PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. PilY1 appears to be located in both the membrane and the external fimbrial fractions. Similar to pir|H82802 (39%). SignalP reporting Signal peptide; Function unclear
YP_934421.1	In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similar to trembl|Q82TX3 (50%) and to pir|G82857 (43%). Pfam (PF00114): Pilin (bacterial filament) SignalP reporting Signal peptide. TMHMM reporting one Tmhelix; Function unclear
YP_934422.1	Conserved hypothetical protein. Homology to rsc0810 of R. solanacearum of 71% (trembl|Q8Y180). InterPro: Uncharacterized protein family UPF0033 (IPR001455). Pfam: Uncharacterized protein family UPF0033. no signal peptide. no TMH; Family membership
YP_934423.1	Conserved hypothetical protein. Homology to cv0524 C. violaceum of 42% (trembl|Q7P0P2). Pfam: Peptidase family M48. signal peptide. no TMHs
YP_934424.1	Molybdenum cofactor biosynthesis protein C. Together with moaA is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z (By similarity). InterPro: MoaC family moaC: molybdenum cofactor biosynthesis protein C.; High confidence in function and specificity
YP_934425.1	Conserved hypothetical protein. Homology to orf11 of A. vinelandii of 63% (trembl|Q44537). no domains predicted. no signal peptide. no TMHs.
YP_934426.1	Probable ATP-binding component of tungstate ABC transporter. Homology to tupC of E. acidaminophilum of 40% (tremble: Q93KD4). PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR tungstate. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: ABC transporter Interpo: ABC-transporter (IPR003439), AAA-ATPase (IPR003593), ATP/GTP-binding site motif A (loopP) (IPR001687) no signal peptide no TMHS; Family membership
YP_934427.1	Probable tungstate permease. Homology to tupB of E. acidaminophilum of 40% (tremble: Q93KD5) Permase of an abc-transport system involved in transport of oxyanions. no signal peptide probable 5 TMHs; Family membership
YP_934428.1	Hypothetical secredted protein. no homology of the entire protein to the data bank. no domains predicted signal peptide no TMHs
YP_934429.1	Conserved hypothetical secreted protein. Homology to orf of P.aeruginosa of 30% (ZP_00137401). No domains predicted. Signal peptide reported present. No TMH reported present.; Conserved hypothetical protein
YP_934430.1	Conserved hypothetical protein. Homology to ebA5010 of Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebA5010(KEGG)). no domains predicted. no signal peptide. no TMHs
YP_934431.1	Conserved hypothetical protein. Homology to Rgel02003612 of Rubrivivax gelatinosus PM1 of 51% (gi|47572157|ref|ZP_00242203.1|(NBCI ENTREZ)). Pfam: This family ThiS (thiaminS) is a 66 aa protein involved in sulphur transfer. This family of proteins have two conserved Glycines at the COOH terminus. MoaD, a protein involved sulphur transfer in molybdopterin synthesis, is about the same length and shows limited sequence similarity to ThiS. Both have the conserved GG at the COOH end. no signal peptide. no TMHs
YP_934432.1	Putative oxidoreductase. Homology to narC of C. perfringens of 27% (trembl|Q9WX91) InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs purD: phosphoribosylamine--glycine lig; Family membership
YP_934433.1	Probable aldehyde ferredoxin oxidoreductase. Homology to aorA of E. acidodaminophilum of 47% (trembl|Q93KC8) InterPro: Aldehyde ferredoxin oxidoreductase (IPR001203) Pfam: Aldehyde ferredoxin oxidoreductase, N-terminus; Aldeyhde ferredoxin oxidoreductase, damains 2&3 no TMHs no signal peptide; High confidence in function and specificity
YP_934434.1	Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs
YP_934435.1	Similar to TREMBL:Q8XUQ7 (42% identity); TREMBL:Q8PPN1 (40% identity); SWISSPROT:P28614 (37% identity). Pfam (PF02954): Bacterial regulatory protein,Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_934436.1	Probable cytochrome c550. Homology to exaB of P. aeruginosa of 57% (trembl|Q9Z4P8) Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system InterPro: Cytochrome c class I ((IPR003088) Pfam: Cytochrome c signal peptide no TMHs; High confidence in function and specificity
YP_934437.1	Conserved hypothetical amino acid-binding protein. Homology to pp2676 of P. putida of 34% (trembl|Q88JH3). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR amino acids. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein /glutamate receptor (IPR001311). Pfam: Bacterial extracellular solute-binding protein. singal peptide. no TMHs; Specificity unclear
YP_934438.1	Conserved hypothetical protein TMHMM2 reporting the presence of 1 TMH's. No Signal peptide present. Has 2 WD40 repeats;SMART;SM00320, Beta-transducin (G-beta) is one of the three subunits (alpha, beta, and gamma) of the guanine nucleotide-binding proteins (G proteins) which act as intermediaries in the transduction of signals generated by transmembrane receptors (see IPR001632). The alpha subunit binds to and hydrolyzes GTP; the functions of the beta and gamma subunits are less clear but they seem to be required for the replacement of GDP by GTP as well as for membrane anchoring and receptor recognition.; Function unclear
YP_934439.1	Conserved hypothetical cytochrome B561. Homology to cv3278 of C. violaceum of 41%. Involved in electronen transfer. no domains. no signal peptide. 4 TMHs; Family membership
YP_934440.1	Probable cytochrome c-552 precursor. Homology to cyt of N. europaea of 50% (sprot|C552_NITEU). ELECTRON DONOR FOR CYTOCHROME CD1 IN NITRITE AND NITRATE RESPIRATION. InterPro: Cytochrome c class I (IPR003088); Cytochrome c, class ID (IPR002324); cytochrome c, class IC (IPR008168) Pfam: cytochrome c signal peptide no TMHs; High confidence in function and specificity
YP_934441.1	Conserved hypothetical protein. Homology to OB2533 of O.iheyensis of 64% (trembl:Q8ENF0). Has PF05610,Protein of unknown function (DUF779);IPR008497;This family consists of several bacterial proteins of unknown function. No signal peptide or TMH present.
YP_934442.1	Aldehyde dehydrogenase (NAD+). Homology to aldA of X. autotrophicus of 76% (trembl|O50203). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no TMHs; High confidence in function and specificity
YP_934443.1	Similar to TREMBL:Q7P122 (29% identity); TREMBL:Q87YQ3 (29% identity); SWISSPROT:P28614 (28% identity). Pfam (PF00158): Sigma-54 interaction domain.; Specificity unclear
YP_934444.1	Zinc transporter zitB (formaly ybgR).Involved in zinc efflux across the cytoplasmic membrane thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc (By similarity).The E.coli zitB gene encodes a Zn(II) transporter belonging to the cation diffusion facilitator family.; High confidence in function and specificity
YP_934445.1	Conserved hypothetical protein. Homology to PSPTO5055 of P.syringae of 36% (trembl:Q87V84). No domains predicted. No signal peptide or TMH reported present.
YP_934446.1	Conserved hypothetical protein. Homology to PSPTO5054 of P.syringae of 35% (trembl:Q87V85). No domains predicted. No TMHs. No signal peptide.
YP_934447.1	Conserved hypothetical secreted protein. Homology to ws0556 of W. succinogenes of 51% (trembl|Q7MSD6). Pfam: DUF411. The function of the members of this bacterial protein family is unknown. Some members may be involved in conferring cation resistance. signal peptide. TMH in signal peptide; Conserved hypothetical protein
YP_934448.1	Two component sensor kinase,; High confidence in function and specificity
YP_934449.1	Transcriptional activator protein,; High confidence in function and specificity
YP_934450.1	Conserved hypothetical secreted protein. Homology to pp5391 of P. putida of 31% (trembl|Q88BZ2). no domains predicted. signal peptide. no TMHs.; Conserved hypothetical protein
YP_934451.1	AAH:63279: 42% identity, 55% similarity Anti-oncogene; SH3 domain; Repeat; Description:SAM and SH3 domains containing protein 1 (proline-glutamate repeat-containing protein). Gene name(s) sash1 or pepe1 contains 1 SH3 domain. similarity: contains 2 sterile alpha motif (SAM) domains May have a role in a signaling pathway. Could act as a tumor supressor. InterPro: IPR001660; SAM. IPR001452: SH3. Pfam:PF00536; SAM; 2. PF00018:SH3; 1. SMART:SM00454; SAM; Function unclear
YP_934452.1	Putative outer membrane efflux protein involved in cobalt-zinc-cadmium resistance (Cation efflux system protein czcC). Homology to czcC of R. eutropha of 24%. czcC protein appears to modify the specificity of the system perhaps by acting on the czcB protein. When the czcC protein is added to czcA and czcB the efflux systems gained specificity for Cd(2+)and Co(2+) signal peptide no TMHs; Family membership
YP_934453.1	Multicopper oxidases are enzymes that possess three spectroscopically differentcopper centers. Similar to TREMBL:Q7X4G1 (71% identity); TREMBL:Q8U8U7 (71% identity); TREMBL:Q92ZC7 (70% identity). InterPro (IPR001117): Multicopper oxidase type 1. Pfam (PF00394): Multicopper oxidase. SignalP reporting signal peptide.; Function unclear
YP_934454.1	CopC: copper tolerance protein.CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm. 43% Cu-oxidase. InterPro:IPR008972; Cupredoxin. Signal pepetide:present. TMhelix:1.; Function unclear
YP_934455.1	Conserved hypothetical secreted protein. Homology to SMc02284 of S. meliloti of 38% (trembl|Q92S41(SRS)). Has PF07076:IPR009780;Protein of unknown function (DUF1344):This family consists of several short,hypothetical bacterial proteins of around 80 residues in length. Members of this family are found in Rhizobium,Agrobacterium and Brucella species. The function of this family is unknown. Signal peptide predicted. No TMHs; Conserved hypothetical protein
YP_934456.1	Conserved hypothetical outer membrane efflux. Homology to ebA2169 Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA2169(KEGG)). Pfam: Outer membrane efflux protein. signal peptide. probable 1 TMH in signal peptide.; Conserved hypothetical protein
YP_934457.1	Putative membrane fusion protein silB precursor. COMPONENT OF THE SIL CATION-EFFLUX SYSTEM THAT CONFERS RESISTANCE TO SILVER. MAY BE PART OF A THREE-COMPONENT CATION/PROTON ANTIPORTER.; High confidence in function and specificity
YP_934458.1	Region start changed from 3242195 to 3242423 (-228 bases)
YP_934459.1	Similar to E.coli CopA: copper transporting P-type ATPase protein, involved in the uptake and metabolism of copper(EC 3.6.3.4).Involved in copper transport(By similarity). Putative cation transporting P-type ATPase (EC 3.6.3.-).; High confidence in function and specificity
YP_934460.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs. HTH predicted
YP_934461.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934462.1	Carboxymuconolactone decarboxylase family protein,33% identity to TrEMBL;Q88K69. Has PF02627,Carboxymuconolactone decarboxylase family; Carboxymuconolactone decarboxylase (CMD)is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins (e.g. O67982) CMD represents the C-terminal domain,Abhydrolase_1 represents the N-terminal domain.; Function unclear
YP_934463.1	27% similarity to Hypothetical protein ycxA (ORF5)of Bacillus subtilis. 12 predicted transmembrane helices with signal peptide. 54% identity, 69% similarity to Pseudomonas putida membrane protein. InterPro: General substrate transporters 2A0111: Oxalate/Formate Antiporter; Function unclear
YP_934464.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Has Signal peptide
YP_934465.1	Putative RNA polymerase sigma factor sigZ. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Similar to SWISSPROT: sprot|SIGZ_BACSU (23% Bacillus subtilis, RNA polymerase sigma factor SigZ) / sprot|RPSH_PSEAE (28% Pseudomonas aeruginosa, RNA polymerase sigma-h factor (sigma-30), AlgU or AlgT) InterPro: IPR000838 Sigma70_ECF. Pfam: PF07638 ECF sigma factor.; High confidence in function and specificity
YP_934466.1	Probable chromate transport protein.This protein reduces chromate accumulation and is essential for chromate resistance.Integral membrane protein.Induced by chromate. 27% Chromate_transpt. Pfam:PF02417; Chromate_transp; 2. TIGRFAMs:TIGR00937; 2A51; 1. TMHelix: 11. InterPro: Chromat transporter 2A51: Chromate Ion Transporter; High confidence in function and specificity
YP_934467.1	Probable Chromate resistance signal peptide protein, 49% Identity to TrEMBL; Q7NZK1, Q8XSC4. Has Signal Pepride.
YP_934468.1	Protein yhhW. SPROT:P46852: 51% identity, 69% similarity entry represents N-terminal domain of Pirin proteins from both eukaryotes and prokaryotes. The function of Pirin is unknown but the gene coding for this protein is known to be expressed in all tissues in the human body InterPro; IPR007113; Cupin_sup. InterPro; IPR003829; Pirin_N. Pfam; PF02678; Pirin; TIGR00292: thiazole biosynthesis enzyme Absence of transmembrane helices (TMHMM predicted).; Function unclear
YP_934469.1	Conserved hypothetical membrane protein. Homology to VPA0043 of Vibrio parahaemolyticus of 64% (trembl|Q87K55). Pfam: TQO small subunit DoxD. DoxD is a subunit of the terminal quinol oxidase present in the plasma membrane of Acidianus ambivalens, with calculated molecular mass of 20.4 kDa. Thiosulphate:quinone oxidoreductase (TQO) is one of the early steps in elemental sulphur oxidation. A novel TQO enzyme was purified from the thermo-acidophilic archaeon Acidianus ambivalens and shown to consist of a large subunit (DoxD) and a smaller subunit (DoxA). The DoxD- and DoxA-like two subunits are fused together in a single polypeptide. Signal peptide. 3 TMHs; Conserved hypothetical protein
YP_934470.1	Transcriptional regulator, LysR family,; Family membership
YP_934471.1	SPROT:Q92PU3: 71% identity; 82% similarity Flavoprotein wrbA1. cofactor:binds 1 fmn per monomer (by similarity). similarity:belongs to the wrba family; contains 1 flavodoxin-like domain. InterPro:IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam: PF00258; flavodoxin; 1. Absence of signal peptide (Signal P predicted) and transmembrane helices (TMHMM predicted) met_pdase_I: methionine aminopeptidase t; High confidence in function and specificity
YP_934472.1	Conserved hypothetical secreted protein. Homology to ebA582 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA582(KEGG)). No domains predicted. Signal P reporting signal peptide. No TMHs; Conserved hypothetical protein
YP_934473.1	Probable two-component response regulator,; Family membership
YP_934474.1	Putative two-component sensor histidine kinase,only very low similarity to SWISSPROT: sprot|DEGS_BACBR (13% Bacillus brevis, DegS) InterPro: IPR003661 His_kinA_N. Pfam: PF00672 HAMP domain. PF02518 Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase TMHMM reporting 2 transmembrane helices. Sensor protein degS (EC 2.7.3.-). INVOLVED IN A SENSORY TRANSDUCTION PATHWAY THAT AFFECT THE PRODUCTION OF ENZYMES THAT DEGRADE POLYMERIC CARBON AND NITROGEN SOURCES. DEGS PROBABLY ACTS AS A KINASE THAT PHOSPHORYLATES DEGU.; Function unclear
YP_934475.1	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 73% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present.; High confidence in function and specificity
YP_934476.1	Pentapeptide repeat family protein, 36% identity(46% similarity) to TrEMBL;Q88JH6. Signal P reporting Signal Peptide present. Has 3 copies of PF00805,Pentapeptide repeats;IPR001646, 5peptide_repeat;These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix . The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid.; Conserved hypothetical protein
YP_934477.1	Putative cytochrome c550. Homology to exaB of P. aeruginosa of 37% (trembl|Q9Z4P8). Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation. InterPro: Cytochrome c class I (IPR003088) Pfam: cytochrome c signal peptide no TMHs; Function unclear
YP_934478.1	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 53% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. TMhelix:1; High confidence in function and specificity
YP_934479.1	Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected.; Conserved hypothetical protein
YP_934480.1	Conserved Hypothetical protein (pir:H95862; 47% identity ), putative hydrolase (TREMBL: Q88JH1; 54% identity, 66% similarity) putative cyclase (TREMBL: Q93IZ0) putative alkylsufatase/betalactamase (rba:RB11502) Metallo beta lactamase superfamily (Pfam) Signal P; TMHMM reporting transmembrane helices S18: ribosomal protein S18; High confidence in function and specificity
YP_934481.1	Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein.; High confidence in function and specificity
YP_934482.1	Putative two-component sensor histidine kinase,; Specificity unclear
YP_934483.1	Probable transcriptional regulator, LuxR family,; Specificity unclear
YP_934484.1	Putative methyl-accepting chemotaxis protein,; Conserved hypothetical protein
YP_934485.1	Conserved hypothetical protein. Homology to an orf of M. magnetotacticum of 33% (ZP_00053175). No domains predicted. No TMHs. No signal peptide
YP_934486.1	Putative Transposase,38% identity(55% similarity)to TrEMBL;Q877R1, Putative receptor protein (Transposase) [BT1893] [Bacteroides thetaiotaomicron VPI-5482]. Has PF01609:Transposase DDE domain;Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4 P03835, IS421 P11901, IS5377 Q45620, IS427 , IS402, IS1355 O69604, IS5,which was original isolated in bacteriophage lambda. IPR002559:Transposase_11. GO:0004872;Molecular function: receptor activity. Signal peptide present. NO TMH reported present.; Family membership
YP_934487.1	Hypothetical secreted protein. no homology to the data bank. Pfam: DUF1555. signal peptide. TMH in signal peptide
YP_934488.1	Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein). May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1 and thereby contribute to the regulation of telomere length. TREMBL:Q800E0:34%; Q8YTG9:36% identity. InterPro: Ankyrin-repeat Mop: molybdenum-pterin binding domain Presence of signal peptide (SignalP) but absence of transmembrane helices; Function unclear
YP_934489.1	Similar to TREMBL:Q82SQ0 (50% identity ,67% similarity).; Function unclear
YP_934490.1	Putative Dihydrofolate reductase.; Function unclear
YP_934491.1	Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity
YP_934492.1	Peroxidase/catalase (EC 1.11.1.6). Bifunctional exhibiting both a catalase and broad- spectrum peroxidase activities.Peroxidases are haem-containing enzymes that use hydrogen peroxide as the electron acceptor to catalyse a number of oxidative reactions.Bacterial catalase-peroxidases are approximately twice the size of plant and fungal haem peroxidases. Sequence analysis suggests that this doubling in length can be ascribed to gene duplication, whereby each half is; High confidence in function and specificity
YP_934493.1	Similar to TREMBL:Q88PY7 (90% identity); SWISSPROT:P21367 (87% identity); TREMBL:Q7W0U0 (85% identity). InterPro (IPR000868): Isochorismatase hydrolase. Pfam (PF00857): Isochorismatase family.; Specificity unclear
YP_934494.1	Hypothetical protein PA2418. Pirin related protein of unknown function. TREMBL:Q7VUX8: 69% identity, 81% similarity. InterPro:IPR008778; Pirin_C. IPR003829; Pirin_N. Pfam: PF02678; Pirin; 1. PF05726; Pirin_C InterPro: DUF209 No signal peptide present (Signal P predicted). No transmembrane helices present (TMHMM predicted). hypD: hydrogenase expression/formation pr; Specificity unclear
YP_934495.1	Probable transcriptional regulator, LysR family,; Family membership
YP_934496.1	DNA-binding protein or Dihydrofolat-Reductase ???; Function unclear
YP_934497.1	Iron-regulated outer membrane protein. TonB-dependent receptor protein. Homolog to fpvA, a ferripyoverdine receptor precursor in P. aeruginosa. Similar to PupA protein of P. putida WCS,this protein is a receptor for the iron-bound form of pesudobactin, a compound structurally very; High confidence in function and specificity
YP_934498.1	Conserved hypothetical membrane protein. Homology to IL2513 of Idiomarina loihiensis of 37% (gnl|keqq|ilo:IL2513(KEGG)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_934499.1	Conserved hypothetical membrane protein. Homology to PA2403 of Pseudomonas aeruginosa of 38% (trembl|Q8G8F6). Has 3 copies of PF03929, PepSY-associated TM helix;IPR005625 pEPsy_tm; This domain represents a conserved TM helix found in bacterial proteins. Has PF03413, Peptidase propeptide and YPEB domain; IPR005075,Propep_PepSY:This region is likely to have an protease inhibitory function (personal obs:C Yeats). This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB. no signal peptide. 4TMHs; Conserved hypothetical protein
YP_934500.1	Ferrioxamine B receptor precursor, FhuF. Iron-regulated outer membrane protein that bind and uptake ferrioxamine in association with the TonB protein. Involved in the reduction of ferric iron in cytoplasmic ferrioxamine B. Binds 1 2Fe-2S cluster. In e.coli the fhuF gene reacts very sensitive to minor changes of Fe2+ and Fur(Ferric uptake regulator). SWISSPROT: FOXA_SALTY. Prim. accession #:Q56145 EMBL: AE008712; AAL19318.1; AF060876; AAC15464.1; U62282; AAB04552.1; InterPro:IPR000531; TonB_boxC. Pfam: PF00593; TonB_dep_Rec; 1. PROSITE: PS00430; TONB_DEPENDENT_REC_1; FALSE_NEG. PS01156; TONB_DEPENDENT_REC_2; FALSE_NEG.; High confidence in function and specificity
YP_934501.1	Hypothetical protein predicted by Glimmer/Critica. InterPro: Esterase/lipase/thioesterase family active site (IPR000379), GCN5-realted N-actetyltransferase (IPR000182). no signal peptide. no TMHs
YP_934502.1	Conserved hypothetical secreted protein. Homology to NE2572 of N.europaea of 46% (tremble:Q82RZ3). Has PF05951, Bacterial protein of unknown function (DUF882);IPR010275; This family consists of a series of hypothetical bacterial proteins of unknown function. Signal Peptide Present. No TMH present.; Conserved hypothetical protein
YP_934503.1	Putative periplasmic protein [ycbB], 39% identity(57% similarity) to TrEMBL;Q82RZ2.Q9A853(30% identity) Signal Peptide Present. Has PF01471, Putative peptidoglycan binding domain; IPR002477 PG_binding; This domain, peptidoglycan binding domain 1, may have a general peptidoglycan binding function. It is composed of three helices and is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. * Muramoyl-pentapeptide carboxypeptidase (EC:3.4.17.8) * N-acetylmuramoyl-L-alanine amidase cwlA precursor (cell wall) hydrolase, autolysin, EC:3.5.1.28) * Autolytic lysozyme (1,4--N-acetylmuramidase, autolysin, EC:3.2.1.17) * Membrane-bound lytic murein transglycosylase B; Family membership
YP_934504.1	Conserved hypothetical membrane protein. Homology to XAC149 of X. axonopodis of 41% (trembl|Q8PLP4(SRS)). Pfam: DedA family. This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions. no signal peptide. 4 TMHs.; Conserved hypothetical protein
YP_934505.1	Conserved hypothetical formylglutamte amindohyrolase. Homology to hutG of B. bronchiseptica of 53% (trembl|Q7WEA2). Catalyses the terminal reaction in the five-step pathway for histidine utilisation. no signal peptide. no TMHs; Conserved hypothetical protein
YP_934506.1	Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; Family membership
YP_934507.1	Sarcosine oxidase, subunit beta counts to the FAD dependent oxidoreductases. Similar to trembl|Q82M71 (29%) and to trembl|Q9V0K7 (26%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site ProSite (PS50204): UBA/THIF-type NAD/FAD binding fold; Specificity unclear
YP_934508.1	Probable electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 54% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein beta-subunit (IPR000049) Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity
YP_934509.1	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 49% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity
YP_934510.1	Conserved hypothetical protein. Homology to BB1278 of B.bronchiseptica of 35% (trembl:Q7WMW2). Has PF05962,Bacterial protein of unknown function (DUF886);IPR010282; This family consists of several hypothetical bacterial proteins of unknown function. No signal peptide or TMH present.
YP_934511.1	Probable electron transfer flavoprotein-ubiquinone oxidoreductase. Homology to etfdh of H. sapiens of 53% (sprot|ETFD_HUMAN) Accepts electrons and reduces ubiquinone. Pfam: FAD_binding_3; ETF_QO no signal peptide no TMHs; High confidence in function and specificity
YP_934512.1	Putative DNA binding helix-turn helix protein,; Family membership
YP_934513.1	Glutamine synthetase III plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Similar to trembl|Q98A06 (58%) and to sprot|GLN3_RHILP (38%). Pfam (PF03951): Glutamine synthetase, beta-Grasp domain Pfam(PF00120): Glutamine synthetase, catalytic domain; High confidence in function and specificity
YP_934514.1	Glutamine amidotransferase, class-II protein, glxB (purF). Similar to sprot|GLXB_RHIME (46%) and to trembl|Q882P3 (49%). Glutamine amidotransferase catalyse the removal of the ammonia group from glutamine and then to transfer this group to a substrate to form a new carbon-nitrogen group. This catalytic activity is known as glutamine amidotransferase (GATase). On the basis of sequence similarities two classes of GATase domains have been identified class-I and class-II (also known as purF-type). Enzymes containing Class-II GATase domains include amido phosphoribosyltransferase, which catalyses the first step in purine biosynthesis. InterPro (PF00310): Glutamine amidotransferase class-II; High confidence in function and specificity
YP_934515.1	Probable protein GlxC. Similar to sprot|GLXC_RHIME (59%) and to pir|A96211 (51%). Pfam (PF01493): GXGXG; Family membership
YP_934516.1	Glutamate synthase, large subunit. Similar to sprot|GLXD_RHIME (87%). Glutamate synthase (GltS) is a complex iron-sulphur flavoprotein that catalyses the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the bacterial, yeast and plant pathways for ammonia assimilation. Pfam: Conserved region in glutamate synthase; Specificity unclear
YP_934517.1	PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ4 (100%) and to trembl|Q9RBK0 (78%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity
YP_934518.1	Ammonium transporter 1 member 2 (LeAMT1;2). Involved in high affinity ammonium uptake. TREMBL:Q8RP88: 100% identity (published) InterPro: IPR001905; Ammonium_transpt. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp amt: ammonium transporter SignalP predicted signal peptide (probability 0.999) TMHMM predicted 11 transmembrane helices; High confidence in function and specificity
YP_934519.1	Conserved hypothetical secreted protein. Homology to ECA3203 of Erwinia carotovora of 58% (tremble:Q6D293). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_934520.1	Outer membrane porin protein 32 precursor (OMP32). Forms anion selective channels.; Specificity unclear
YP_934521.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted .no signal peptide. no TMHs
YP_934522.1	Putative AraC family,transcriptional regulator, 28% Identity to TrEMBL;Q62GH5,Q6QEJ0,Q9HWT4 Has SMART;SM00342,HTH_ARAC, helix_turn_helix, arabinose operon control protein;IPR000005; Many bacterial transcription regulation proteins bind DNA through a 'helix-turn-helix' (HTH) motif. One major subfamily of these proteins is related to the arabinose operon regulatory protein AraC. Except for celD all of these proteins seem to be positive transcriptional factors.Although the sequences belonging to this family differ somewhat in length, in nearly every case the HTH motif is situated towards the C-terminus in the third quarter of most of the sequences. The minimal DNA binding domain spans roughly 100 residues and comprises two HTH subdomains; the classical HTH domain and another HTH subdomain with similarity to the classical HTH domain but with an insertion of one residue in the turn-region. The N-terminal and central regions of these proteins are presumed to interact with effector molecules and may be involved in dimerization.; Conserved hypothetical protein
YP_934523.1	Conserved hypothetical secreted protein. Homology to aciad2673 of Acinetobacter sp. of 53% (trembl|Q6F937). no domains reported. signal peptide. no TMHs; Conserved hypothetical protein
YP_934524.1	Probable succinate semialdehyde dehydrogenase [NAD(P)+]. Homology to thmS of Pseudonocardia sp. K1 of 46% (trembl|Q9F3V7). Is capable of oxidizing substrates using NADP as cofactor. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership
YP_934525.1	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 37% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present.; High confidence in function and specificity
YP_934526.1	Probable outer membrane receptor TonB-dependent for iron transport. 41% AAC74533.1 InterPro: IPR000531 TonB_receptor.IPR010105; TonB_siderophor. Pfam: PF00593; TonB_dep_Rec; 1. TonB-box domain; High confidence in function and specificity
YP_934527.1	Hypotheical secreted protein. No homology of the entire protein to the data bank. no domains predicted. no TMHs. signal peptide.
YP_934528.1	Conserved hypothetical protein. Homology to ra0176 of S. meliloti of 31% (trembl|Q930L9). Pfam: Uncharacterized ACR, YneC family. no signal peptide. no TMHS
YP_934529.1	Conserved hypothetical secreted protein. Homology to Reut02004453 of Ralstonia metallidurans of 38% (gi|48768314|ref|ZP_00272664.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs.; Conserved hypothetical protein
YP_934530.1	Conserved hypothetical secreted protein. Homology to RS04458 of Ralstonia solanacearum of 31% (tremble:Q8Y292). No domains predicted .Signal peptide reported. NO TMH present.; Conserved hypothetical protein
YP_934531.1	Conserved hypothetical peptidase. Homology to rsc0445 of R. solanacearum of 50% (trembl|Q8Y291). Pfam: Peptidas_C39. Lantibiotic and non-lantibiotic bacteriocins are synthesised as precursor peptides containing N-terminal extensions (leader peptides) which are cleaved off during maturation. Most non-lantibiotics and also some lantibiotics have leader peptides of the so-called double-glycine type. These leader peptides share consensus sequences and also a common processing site with two conserved glycine residues in positions -1 and -2. The double- glycine-type leader peptides are unrelated to the N-terminal signal sequences which direct proteins across the cytoplasmic membrane via the sec pathway. Their processing sites are also different from typical signal peptidase cleavage sites, suggesting that a different processing enzyme is involved. signal peptide. no TMHs; Conserved hypothetical protein
YP_934532.1	Hypothetical secreted protein. No good homology over the entire length in DB. No domains predicted. Signal Peptide present. No TMH present.
YP_934533.1	Conserved hypothetical secreted protein. Homology to RS04455 of R.solanacearum of 50% (tremble:Q8Y289). No domains predicted. Signal P reporting signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_934534.1	Probable transcriptional regulatory protein,; Specificity unclear
YP_934535.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. TMH in signal peptide.
YP_934536.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934537.1	Hypothetical membrane protein. no homology to the data bank. no domains predicted. no signal peptide. 3 TMHs
YP_934538.1	Hypothetical membrane protein. no homology to the data bank. no domains predicted. signal peptide. 2 TMHs
YP_934539.1	Conserved hypothetical protein. Homology to Rgel02002356 of Rubrivivax gelatinosus of 47% (gi|47573226|ref|ZP_00243265.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.
YP_934540.1	conserved hypothetical protein. Homology to Rgel02002355 of Rubrivivax gelatinosus of 41% (gi|47573225|ref|ZP_00243264.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.
YP_934541.1	Probable formate dehydrogenase (NADP+), alpha subunit. Homology to fdh1A of M. extorquens of 60% (trembl|Q8KTI7). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655); Respiratory-chain NADH dehydrogenase 75 kD subunit (IPR000283); Ferredoxin (IPR001041); 4Fe-4S ferredoxin, iron-sulfur binding domain (IPR001450) Pfam: 2Fe-2S iron-sulfur cluster binding domain; 4Fe-2S binding doami; Molybdopterin oxidase; Molybdopterin dinucloetide binding no signal peptide no TMHs; High confidence in function and specificity
YP_934542.1	Probable formate dehydrogenase (NADP+), beta subunit Homology to fdh1B of M. extorpuens of 55% (trembl|Q8KTI8) Pfam: Respiratory-chain NADH dehydrogenase 24 kD subunit; Respiratory-chain NADH dehydrogenase 51 kD subunit. no signal peptide no TMHs; High confidence in function and specificity
YP_934543.1	converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation
YP_934544.1	Probable rubredoxin. Homology to ruba of A. calcoaceticus of 42% (sprot|RUBR_ACIAD). Involved in the hydrocarbon hydroxylating system to convert dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. Pfam: Rubredoxin no singal peptide no TMHs; Family membership
YP_934545.1	ZP_00167050: 52% identity; 70% similarity. Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta- crystallin). DOES NOT HAVE ALCOHOL DEHYDROGENASE ACTIVITY. BINDS NADP AND ACTS THROUGH A ONE-ELECTRON TRANSFER PROCESS. ORTHOQUINONES ARE THE BEST SUBSTRATES. MAY ACT IN THE DETOXIFICATION OF XENOBIOTICS (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N TIGRFAM: 2A0302: arginine/ornithine antiporter tdh: L-threonine 3-dehydrogenase; Function unclear
YP_934546.1	COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). catalytic activity:-(3s)-3-hydroxyacyl-coa = trans-2(or 3)-enoyl- coa + H(2)o. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:- IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 72/262 (27%) Number of predicted TMHs: 0; Family membership
YP_934547.1	Hypothetical protein HI0386. TREMBL:Q84HI6: 48% identity, 66% similarity 4-hydroxybenzoyl-CoA thioesterase is a protein of 141 amino-acid residues that assemble as an homotetramer. An aspartate in the N-terminal domain is thought to participate in the catalytic mechanism 4-hydroxybenzoyl-CoA + H2 O = 4-hydroxybenzoate + CoA IPR006683; Thioesterase superfamily IPR006684; 4-hydroxybenzoyl-CoA thioesterase Pfam:PF03061; 4HBT; No transmembrane helices (TMHMM predicted) TIGR00051: conserved hypothetical protein; High confidence in function and specificity
YP_934548.1	TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Description:lactonase. InterPro:IPR000379; Ser_estrs Pfam:abhydrolase_2, Thioesterase aroC: chorismate synthase Signal P predicted nonsecretiory protein without transmembrane helices.; High confidence in function and specificity
YP_934549.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q84HI4 (80%) and to trembl|Q89VH8 (45%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear
YP_934550.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q84HI3 (79%) and to sprot|LIVG_ECOLI (37%). Pfam (PF00005): ABC transporter ProSite (PS50101): ATP/GTP-binding site motif A (P-loop) Smart (SM00382): AAA ATPase superfamily; Specificity unclear
YP_934551.1	Putative branched-chain amino acid transport permease. Homology to livM of E. coli of 31% as well as genes coding for a new pathway of aerobic benzoate meabolisme in A. evansii (77%). Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: Branched-chain amino acid transport system. probable signal peptide probable 8 TMHs; Specificity unclear
YP_934552.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q84HI2 (91%), to trembl|Q89VI1 (47%), to sprot|LIVH_ECOLI (27%) and to sprot|BRAD_PSEAE (30%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting six Tmhelix.; Specificity unclear
YP_934553.1	In enteric bacteria such E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar trembl|Q93FB9 (84%) and to sprot|LIVJ_ECOLI (21%). Pfam (PF01094): Receptor family ligand binding region Pfam (PF04392): Protein of unknown function (DUF534) SignalP reporting Signal peptide.; Specificity unclear
YP_934554.1	Conserved hypothetical protein. Homology Daro03002253 of Dechloromonas aromatica of 43% (gi|53730397|ref|ZP_00151095.2|(NBCI ENTREZ)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96_ALCEU is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger. No TMHs. No signal peptide.
YP_934555.1	Entry name :- TREMBL:Q84HI0 Entry name :-TREMBL:Q8VUF1 InterPro IPR010071; AA_adenyl_dom. IPR000873; AMP-bind. IPR010192; MenE. Pfam PF00501; AMP-binding; 1 Identities = 414/532 (77%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_934556.1	Conserved hypothetical protein. Homology to an orf of A. evnasii of 79% (trembl|Q84HH9). no domains predicted. no signal peptide. no TMHS
YP_934557.1	Aldehyde dehydrogenase (NAD+). Homology to the aldehyce dehydrogenase of the of the benzoate gene cluster of A. evansii of 81% (trembl|Q84HH8). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. Here clustered with genes involved in the aerobic benzoate metabolism. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity
YP_934558.1	consists of N-terminal helix-turn-helix domain and C-terminal shikimate kinase-like domain which may bind benzoyl-CoA; controls inducible expression of the bzd catabolic operon that is involved in the anaerobic catabolism of benzoate
YP_934559.1	cleaves the ring of 2,3-dihydro-2,3-dihydroxybenzoyl-CoA forming 6-hydroxy-3-hexenoyl-CoA
YP_934560.1	Benzoyl-CoA oxygenase component B. 85%; Function unclear
YP_934561.1	Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1.; High confidence in function and specificity
YP_934562.1	catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA
YP_934563.1	Conserved hypothetical protein. Homology to ebA2769 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA2769(KEGG)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96_ALCEU is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger. No TMHs. No signal peptide.
YP_934564.1	GGDEF/EAL/PAS/PAC/GAF-domain containing protein
YP_934565.1	Putative Ribonuclease RNASE_BN Protein, 28% identity to TrEMBL;Q8XPH6. Has PF03631, Ribonuclease BN-like family;IPR004664, RNase_BN: This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; Conserved hypothetical protein
YP_934566.1	Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein
YP_934567.1	Leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (40% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_934568.1	Hydroxymethylglutaryl-CoA lyase, MvaB. It catalyses the conversion of (S)-3-hydroxy-3-methylglutaryl-CoA to acetyl-CoA and acetoacetate during the final step of ketogenesis and leucine catabolism. Similar to trembl|Q8QGJ4 (60%) and to pir|H83394 (56%). InterPro (PF00682): HMG-CoA Lyase-like family; High confidence in function and specificity
YP_934569.1	activates fatty acids by binding to coenzyme A
YP_934570.1	Hypothetical protein ycjD,50% identity(65% similarity) to SwissProt;P45736. Has PF04480, Protein of unknown function (DUF559);IPR007569; No SIgnal Peptide or TMH present. vsr: DNA mismatch endonuclease (vsr)
YP_934571.1	This protein is a component of the acetyl coenzyme a carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-coa. Entry name TREMBL:Q8PDU1 InterPro IPR001882; Biotin_BS. IPR005482; Biotin_carb_C. IPR000089; Biotin_lipoyl. IPR005479; CPase_L_D2. IPR005481; CPase_L_N. Pfam PF02785; Biotin_carb_C; 1. PF00364; Biotin_lipoyl; 1. PF00289; CPSase_L_chain; 1. PF02786; CPSase_L_D2; 1. Identities = 382/661 (57%) Preediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_934572.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_934573.1	Activity:- ATP + 3-methylcrotonoyl-CoA + HCO3- = ADP + phosphate + 3-methylglutaconyl-CoA Entry name:-TREMBL:Q7WDP0 InterPro:- IPR000022; Carboxyl_trans. Pfam:-PF01039; Carboxyl_trans; 1. Identities = 413/535 (77%) Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.098; Family membership
YP_934574.1	Region start changed from 3382650 to 3382614 (-36 bases), , Changed start codon from att to next gtg
YP_934576.1	Hypothetical protein. No homology to the data base. Pfam: Protein tyrosine kinase, Protein kinase domain. Interpro: IPR000719 Protein kinase, IPR002290 Serine/threonine protein kinase, IPR001245 Tyrosine protein kinase, IPR011009 Protein kinase-like. No signal peptide. No TMHs
YP_934578.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 3 TMHs
YP_934579.1	Conserved hypothetical protein. Homology to TdenA01001814 of Thiobacillus denitrificans of 40% (gi|52006871|ref|ZP_00334250.1|(NBCI ENTREZ)). Has PF01402, Ribbon-helix-helix protein, copG family; IPR002145 HTH_CopG; The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected. No TMHs. No signal peptide.
YP_934580.1	Conserved hypothetical protein. Homology to xcc3092 of X. campestris of 51% (trembl|Q8P678). Pfam: Plasmid stabilisation system protein. Members of this family are involved in plasmid stabilisation. The exact molecular function of this protein is not known. no signal peptide. no TMHs
YP_934581.1	Putative transcriptional regulator, deoR-family
YP_934582.1	Conserved hypothetical protein. Homology to stm0409 of S. typhimurium of 46% (tremble:Q7CR38). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. Pfam: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. no signal peptide. no TMHs.
YP_934583.1	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs
YP_934584.1	Entry name:- TREMBL:Q89LX4 Identities = 310/374 (82%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; Family membership
YP_934585.1	Putative ornithine utilization regulator,; Specificity unclear
YP_934586.1	Conserved hypothetical membrane protein, 44% identity to TrEMBL;Q82UI6. Has PF04247;Invasion gene expression up-regulator, SirB;IPR007360;SirB up-regulates Salmonella typhimurium invasion gene transcription. It is,however, not essential for the expression of these genes. Its function is unknown. No signal peptide. 3 TMHs; Conserved hypothetical protein
YP_934587.1	Putative transcriptional regulator,; Family membership
YP_934588.1	Conserved hypothetical membrane protein. Homology to CV2709 of Chromobacterium violaceum of 40% (trembl|Q7NUI9). Has PF04550;Phage holin family 2:Holins are a diverse family of proteins that cause bacterial membrane lysis during late-protein synthesis. It is thought that the temporal precision of holin-mediated lysis may occur through the buildup of a holin oligomer which causes the lysis. IPR007633;Phage_holin_2. TMHMM2 reporting 12 TMH's Present. no signal peptide.; Conserved hypothetical protein
YP_934589.1	Conserved hypothetical protein. Homology to ws1191 of W. succinogenes of 36% (trembl|Q7MRM8). no domains predicted. no signal peptide. no TMHs
YP_934590.1	Conserved hypothetical protein. Homology to CV2710 of C.violaceum of 41% (trembl:Q7NUI8). Pfam: Hemerythrin HHE cation binding domain Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96_ALCEU is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger. No signal peptide. No TMHs.
YP_934591.1	Nitric-oxide reductase subunit C (EC 1.7.99.7) (Nitric oxide reductase cytochrome c subunit) (NOR small subunit).COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION).54% IPR000345; CytC_heme_BS. Pfam; PF00034; Cytochrom_C; 1. SignalP: present TMHelix:1; High confidence in function and specificity
YP_934592.1	Nitric-oxide reductase subunit B (EC 1.7.99.7) (Nitric oxide reductase cytochrome b subunit). 69% similarity to the P.stutzeri NorB protein. COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION). NorB IS THE CATALYTIC SUBUNIT OF THE ENZYME COMPLEX. SHOWS PROTON PUMP ACTIVITY ACROSS THE MEMBRANE IN DENITRIFYING BACTERIAL CELLS. THE MONONITROGEN REDUCTION IS PROBABLY COUPLED TO ELECTRON TRANSPORT PHOSPHORYLATION.Belongs to the heme-copper respiratory oxidase family. Swiss Prot: Q59647. IPR000883; COX1. PF00115; COX1; 1. TMHMM:predicted transmembrane helix present. SignalP: present ccoN: cytochrome c oxidase cbb3-type; High confidence in function and specificity
YP_934593.1	Conserved hypothetical protein. Homology to RS05091 of R.solanacearum of 76% (trembl:Q8Y1C8). No domains present. No TMHs. No signal peptide.
YP_934594.1	Potassium uptake protein. Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH.Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins. 41% NAD_BS. IPR006037; TrkAC. IPR003148; TrkA_N. Pfam:PF02080; TrkA_C; 1. PF02254; TrkA_N; 1. Pfam:KTN: NAD-binding domain.; Specificity unclear
YP_934595.1	Membrane component of the potassium uptake system. 38% Cat_transpt. IPR004772; K_transptTrk. Pfam: PF02386; TrkH; 1. SignalP.present. TMHelix:9.; High confidence in function and specificity
YP_934596.1	Two component system transcriptional regulatory protein, 53% Identity to TrEMBL;Q7W532,Q8XUU6. Has SMART;SM00448,REC, cheY-homologous receiver domain;IPR001789;CheY regulates the clockwise rotation of E. coli flagellar motors. This domain contains a phosphoacceptor site that is phosphorylated by histidine kinase homologues. Has OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription] Has PF00486, Transcriptional regulatory protein, C terminal;IPR001867 Trans_reg_C; This domain is almost always found associated with the response regulator receiver domain (see INTERPRO:IPR001789). It may play a role in DNA binding
YP_934597.1	Probable sensor for high-affinity potassium transport system,; High confidence in function and specificity
YP_934598.1	Nitric-oxide reductase ATP/GTP binding component,NorQ. 68% FGGY_kin. TMHMM:present SignalP: present.; High confidence in function and specificity
YP_934599.1	Conserved hypothetical iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to pbprb0648 of P. profundum (tremblnew|CAG22521). Involved in a membrane generated redox signal. Pfam: 4Fe-4S binding domain no signal peptide 4 TMHs; Conserved hypothetical protein
YP_934600.1	Nitric oxide reductase NorD protein. COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION). FUNCTION UNKNOWN BUT ESSENTIAL FOR THE DENITRIFICATION PROCESS. 35% similarity to B. japonicum NorD. TREMBL:Q89QB3 InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. InterPro:SM00327:von Willebrand factor type A domain SignalP:present. TMHMM: presence of TMHhelix.; High confidence in function and specificity
YP_934601.1	Putative Fnr-like transcriptional activator,; Function unclear
YP_934602.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_934603.1	Putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to rdxB of R. sphaeroides of 39% (sprot|RDXB_RHOSH). Involved in a membrane generated redox signal; required to maintain repression of photosynthesis gene expression in the presence of oxygen. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding doamin no signal peptide probable 5 TMHs; Family membership
YP_934604.1	AAU3 protein precursor,; High confidence in function and specificity
YP_934605.1	Conserved hypothetical membrane protein,; Conserved hypothetical protein
YP_934606.1	Conserved hypothetical cytochrome c5. Homology to nosC of A. eutrophus of 62% (trembl|Q7WX89). This basic c-type monoheme cytochrome has an unusually low redox potential compared with mitochondrial cytochrome c. It is reactive with cytochrome c oxidases but not with reductases. InterPro: Cytochrome c class I (IPR003088) Pfam: Cytorchrome C. signal peptide. no TMHs; Family membership
YP_934607.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934608.1	Conserved hypothetical protein. Homology to Rgel02003456 of Rubrivivax gelatinosus of 68% (gi|47572283|ref|ZP_00242328.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_934609.1	conserved hypothetical secreted protein. Homology to TdenA01000391 of Thiobacillus denitrificans of 42% (gi|52008094|ref|ZP_00335471.1|(NBCI ENTREZ)). no domians predicted. signal peptide. TMH in signal peptide; Conserved hypothetical protein
YP_934610.1	Putative NosL protein. Homology to nosL of S. meliloti of 38% (trembl|O07331). NosL is one of the accessory proteins of the nos (nitrous oxide reductase) gene cluster. NosL is a monomeric protein of 18,540 MW that specifically and stoichiometrically binds Cu(I). The copper ion in NosL is ligated by a Cys residue, and one Met and one His are thought to serve as the other ligands. It is possible that NosL is a copper chaperone involved in metallocenter assembly. probable signal peptide no TMHs; Family membership
YP_934611.1	Membrane protein nosY precursor.INVOLVED IN COPPER PROCESSING. Part of the ABC transporter complex nosDFY involved in copper import. Probably responsible for the translocation of the substrate across the membrane. 43% Similar to the copper permease, nosY in P.stutzeri. TREMBL:Q9F0W1 InterPro:IPR001117; Cu-oxidase. SignalP: present. Number of predicted TMHs:6; High confidence in function and specificity
YP_934612.1	Copper transport ATP-binding protein nosF.INVOLVED IN COPPER PROCESSING/TRANSPORT.Part of the ABC transporter complex nosDFY involved in copper import. 3% ABC_tran; 1. InterPro:IPR003593; AAA_ATPase. IPR003439; ABC_transporter. InterPro:PS50101:ATP/GTP-binding site motif A (P-loop). InterPro:SM00382:AAA ATPase superfamily.; High confidence in function and specificity
YP_934613.1	Copper-binding periplasmic protein precursor. INVOLVED IN COPPER PROCESSING AND TRANSPORT; IN THE ASSEMBLY OF THE COPPER CHROMOPHORES OF NITROUS OXIDE REDUCTASE.Part of the ABC transporter complex nosDFY involved in copper import. Similar to the putative periplasmic-binding protein nosD precursor from: P.fluorescens (36%)TREMBL:Q9F0W3 InterPro:IPR006633; CASH. IPR007742; NosD.IPR006626; PbH1. Pfam:PF05048; NosD; 1. Signal peptide: present.; High confidence in function and specificity
YP_934614.1	Conserved hypothetical transcriptional activator for nitrous-oxide reductase, C-termial domain. Homology to nosr (C-terminal domain) of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebB224(KEGG)). no domains predicted. no signal peptide. probable 3 TMHs; Conserved hypothetical protein
YP_934615.1	Regulatory protein nosR. Transcriptional activation of the nitrous-oxide reductase gene nosZ. Similar to SWISSPROT: sprot|NOSR_PSEST (37% Pseudomonas stutzeri (Pseudomonas perfectomarina), regulatory protein NosR). TMHMM reporting 5 transmembrane helices. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_934616.1	reduces nitrous oxide to nitrogen
YP_934617.1	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs
YP_934618.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_934619.1	Conserved hypothetical protein. Homology to NMA0336 of N.meningitidis of 59% (trembl:Q9JRG4) Has PF01381 Helix-turn-helix:IPR001387:HTH_3;This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases,various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum. No signal peptide or TMH reported present.
YP_934620.1	Conserved hypothetical protein. Homology to ne1518 of N. europaea of 43% (trembl|Q82UG8). no domains predicted. no signal peptide. no TMHs
YP_934621.1	Lyase, putative 6-pyruvoyl tetrahydrobiopterin synthase protein InterPro: 6-pyruvoyl tetrahydropterin synthase TIGRFAM: 6PTHBS: 6-pyruvoyl tetrahydrobiopterin synthase; Specificity unclear
YP_934622.1	Entry name:- TREMBL:Q8XWM4 InterPro:- IPR001522; Desaturase. IPR005804; Fa_desat. Pfam:- PF00487; FA_desaturase; 1. Identities = 244/390 (62%) Prediction: Non-secretory protein Signal peptide probability: 0.008 Number of predicted TMHs: 3; Family membership
YP_934623.1	Region start changed from 3429549 to 3429093 (-456 bases)
YP_934624.1	Putative endonuclease,42% Identity to TrEMBL;Q8XWM2, 33% Identity to TrEMBL;Q8VMF9. Has Signal peptide. Has PLDc, Phospholipase D. Active site motifs; The PLD superfamily includes enzymes involved in signal transduction, lipid biosynthesis, endonucleases and open reading frames in pathogenic viruses and bacteria. PLD hydrolyzes the terminal phosphodiester bond of phospholipids to phosphatidic acid and a hydrophilic constituent. Phosphatidic acid is a compound that is heavily involved in signal transduction. The common features of the family members are that they can bind to a phosphodiester moiety, and that most of these enzymes are active as bi-lobed monomers or dimers.
YP_934625.1	SUN protein; Specificity unclear
YP_934626.1	Conserved hypothetical secreted protein. Homology to ebA651 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA651(KEGG)). InterproterPro (IPR000694): Proline-rich region. SignalP reporting signal peptide. no TMHs
YP_934627.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
YP_934628.1	Conserved hypothetical secreted protein. Homology to orf58 of Pseudomonas sp. of 42% (trembl|Q937A2(SRS)). No domains predicted. Signal P predicts signal peptide present. No TMH present.; Conserved hypothetical protein
YP_934629.1	DNA mismatch repair protein mutL. This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). InterPro: DNA mismatch repair proteins mutL/hexB/PMS1 mutl: DNA mismatch repair protein MutL; High confidence in function and specificity
YP_934630.1	Hypothetical secreted protein no homology of the entire protein to a protein of similar lengt in the data bank no domains predicted signal peptide no TMHs
YP_934631.1	Inhibits transcription at high concentrations of nickel
YP_934632.1	Conserved hypothetical protein. Homology to orfJ of E. coli of 33% (trembl|O70046). no domains predicted .no signal peptide. no TMHs.
YP_934633.1	catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA
YP_934634.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_934635.1	Hypothetical protein, 56% identity(71% similarity) with TrEMBL;Q6LK82 Has PF07209, Protein of unknown function (DUF1415);IPR009858; This family consists of several hypothetical bacterial proteins of around 180 residues in length. The function of this family is unknown. Signal peptide or TMH not present. EIIA-man: PTS system fructose subfamily
YP_934636.1	Hypothetical protein predicted by Glimmer/Critica. no homology of the protein to a protein of similar size. no domains predicted. no signal peptide. no TMHs
YP_934637.1	AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9HW27 (38% identity); SWISSPROT:Q57124 (33% identity). InterPro (IPR001036): Acriflavin resistance protein. Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear
YP_934638.1	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q7W437 (52% identity); TREMBL:Q8EFT5 (32% identity). InterPro (IPR006143): Secretion protein HlyD. Pfam (PF00529): HlyD family secretion protein. TMHMM reporting one transmembrane helix. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership
YP_934639.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_934640.1	Conserved hypothetical membrane protein. This is a family of hypothetical proteins. A number of the sequence records state they are transmembrane proteins or putative permeases.It is not clear what source suggested that these proteins might be permeases and this information should be treated with caution. TREMBL:Q82Y01: 39% identity; 58% similarity. TREMBL:Q8XW51: 37% identity; 53% similarity. InterPro:IPR002549 Pfam: PF01594:Protein of unknown function DUF70 Signal P predicted signal peptide and TMHMM predicted transmembrane helices; Conserved hypothetical protein
YP_934641.1	Region start changed from 3447165 to 3447246 (-81 bases)
YP_934642.1	Haloacid dehalogenase-like hydrolase family is structurally different from the alpha/beta hydrolase family (abhydrolase). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. Similar to trembl|Q82XZ3 (63%) and to pir|B83604 (47%). Pfam (PF00702): haloacid dehalogenase-like hydrolase; Family membership
YP_934643.1	Probable Poly(A) polymerase. Homology to pcnB of E. coli of 41% (sprot|PCNB_ECOLI) POLYMERASE THAT CREATES THE 3POLY(A) TAIL FOUND IN SOME MRNAS. SEEMS TO BE INVOLVED IN PLASMID COPY NUMBER CONTROL. Pfam: Poly A polymerase family no signal peptide no TMHs; Family membership
YP_934644.1	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK). InterPro: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase Pfam:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; High confidence in function and specificity
YP_934645.1	Conserved hypothetical membrane protein. Homology to PA1577 of Pseudomonas aeruginosa of 69% (trembl|Q9I3E0). Has PF04342, IPR007437;Protein of unknown function, DUF486;This family contains several proteins of uncharacterised function. No signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934646.1	Deoxyguanosine kinase, probable (2.7.1.113) InterPro: Thymidylate kinase DTMP_kinase: thymidylate kinase; Family membership
YP_934647.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_934648.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_934649.1	Region start changed from 3453406 to 3453454 (-48 bases)
YP_934650.1	Aminopeptidase catalyzes the removal of single amino acids from the amino terminus of small peptides and probable plays a role in their final digestion. Similar to trembl|Q8XXI8 (50%) and to sprot|AMPN_ECOLI (47%). Pfam (PF01433): Aminopeptidase N, APN (CD13); Specificity unclear
YP_934652.1	Probable cation-transporting ATPase (EC 3.6.3.-).Could mediate calcium influx.Integral membrane protein.Belongs to the cation transport ATPases family (P-type ATPases). Subfamily IIA. 47% similarity to the cyanobacterium Synechocystis sp. PCC 6803, pma1. protein. SWISSPROT:ATA1_SYNY3.P37367 InterPro:IPR001757; ATPase_E1-E2.IPR006068; Cation_ATPase_C.IPR004014; Cation_ATPase_N.IPR008250; E1-E2_ATPase_reg.IPR000695; H_ATPase.IPR005834; Hydrolase. Pfam:PF00689: Cation_ATPase_C;1. PF00690: Cation_ATPase_N;1. PF00122: E1-E2_ATPase;1. PF00702: Hydrolase; 1. SignalP: present. InterPro:PF00702:Haloacid dehalogenase/epoxide hydrolase family.; High confidence in function and specificity
YP_934653.1	Conserved hypothetical RDD family protein. Homology to ne0432 of N. europaea of 42% (trembl|Q82X63(SRS)). Pfam: (by Smart) RDD family This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands. signal peptide. 3 TMHs; Family membership
YP_934654.1	Conserved hypothetical protein. Homology to ebA7126 of Azoarcus sp. EbN1 of 45% (gnl|keqq|eba:ebA7126(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_934655.1	Conserved hypothetical protein. Homology to Daro03002551 of Dechloromonas aromatica of 31% (gi|41723955|ref|ZP_00150845.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs
YP_934656.1	Probable RNA polymerase sigma factor, 62% Identity to TrEMBL;Q8XXN5, Q7P0I2. Has PF04542, Sigma-70 region 2;IPR007627, Sigma70_r2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix,interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation. Has PF04545, Sigma-70, region 4;IPR007630, Sigma70_r4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives. PF00196,Bacterial regulatory proteins, luxR family; The many bacterial transcription regulation proteins which bind DNA through a 'helix-turn-helix' motif can be classified into subfamilies on the basis of sequence similarities. One of these subfamilies which includes proteins with sizes ranging from 74 (gerE) to 901 amino acids (malT), can be further subdivided into two classes on the basis of the mechanism by which they are activated. The first is a class of regulators which belong to a two-component sensory transduction system where the protein is activated by its phosphorylation, generally on an aspartate residue,by a transmembrane kinase. The proteins that belong to this class include bvgA, comA, dctR; degU, evgA, fimZ,fixJ, gacA, glpR, narL, narP, nodW, rcsB and uhpA. The second is a class of regulators which is activated when bound to autoinducer molecules such as N-(3-oxohexanoyl)-L-homoserine lactone (OHHL. The proteins that belong to this class are carR, echR, esaR, expR, lasR, luxR, phzR, rhlR,traR and yenR. The 'helix-turn-helix' DNA-binding motif of these proteins is located in the C-terminal section of the sequence.
YP_934657.1	Acetolactate synthase isozyme III large subunit (AHAS- III) (Acetohydroxy-acid synthase III large subunit) (ALS-III). InterPro: Acetolactate synthase large subunit biosynthetic type TIGRFAM: acolac_lg: acetolactate synthase large subunit, biosynthetic type; High confidence in function and specificity
YP_934658.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_934659.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_934660.1	This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis catalyzing the reaction CDP-diacylglycerol + L-serine = CMP + L-1-phosphatidylserine. Entry name:-SWISSPROT:PSS_HELPY identity:- 34% InterPro:- IPR000462; CDP-OH_P_trans. IPR004533; PssA. Pfam:- PF01066; CDP-OH_P_transf; 1. Number of predicted TMHs: 6 Prediction: Non-secretory protein Signal peptide probability: 0.047(YES); Family membership
YP_934661.1	Two-component system regulatory protein ColR,; High confidence in function and specificity
YP_934662.1	Two-component system sensor protein ColS,; High confidence in function and specificity
YP_934663.1	Similar to TREMBL:P95473 (66% identity); TREMBL:Q87X18 (66% identity); TREMBL:Q87TV0 (61% identity).
YP_934664.1	Conserved hypothetical InaA protein. Homology to inaA of P. putida of 39% (gnl|keqq|ppu:PP0904(KEGG)). Pfam: Lipopolysaccharide kinase (Kdo/WaaP) family. These lipopolysaccharide kinases are related to protein kinases Pkinase. This family includes waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region. It has previously been shown that WaaP is necessary for resistance to hydrophobic and polycationic antimicrobials in E. coli and that it is required for virulence in invasive strains of S. enterica. No signal peptide. No TMHs; Conserved hypothetical protein
YP_934665.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_934666.1	Conserved hypothetical membrane protein. Homology to bb2106 of B. bronchispetica of 55% (trembl|Q7WKK0(SRS)). No domains predicted. signal peptide. 2 TMHs.; Conserved hypothetical protein
YP_934667.1	Flavoprotein wrbA. TREMBL:Q8XZ48:63% identity, 73% similarity; Q7NZW0: 61%, 72% WrbA, related to and slightly larger than flavodoxin. In Escherichia coli, this protein is produced during stationary phase, binds to the trp repressor, and makes trp operon repression more efficient. WrbA does not interact with the trp operator by itself. Three copies are found in Sinorhizobium meliloti InterPro: IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam PF00258: flavodoxin Absence of signal peptide (Signal P predicted) and Transmembrane helices (TMHMM predicted). wrbA2 identical to wrbA1 and wrbA3 by 37% and 23% respectively.; High confidence in function and specificity
YP_934668.1	Putative membrane protein(Ribonuclease BN)36% identity to TrEMBL; Q7NZV9.TrEMBL;Q8XZ47(27% identity). Has PF03631, Ribonuclease BN-like family;IPR004664,RNase_BN;This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; High confidence in function and specificity
YP_934669.1	Hypothetical Protein,20% identity to TrEMBL;Q9HUK7. Very Bad homology with the hits in the DB over entire length of protein. No substantial good hits available. No signal peptide or TMH reported present.
YP_934670.1	50S ribosomal protein L21, 83% Identity to TrEMBL;Q7WQL6,Q7W1P0, Q8XVK8. Has PF00829, Ribosomal prokaryotic L21 protein;IPR001787 Ribosomal_L21p; Ribosomes are the particles that catalyze mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites MEDLINE:11297922,MEDLINE:11290319. About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they belong to - the small (S1 to S31) and the large (L1 to L44). Usually they decorate the rRNA cores of the subunits.
YP_934671.1	involved in the peptidyltransferase reaction during translation
YP_934672.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_934673.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_934674.1	Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs
YP_934675.1	It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership
YP_934676.1	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity
YP_934677.1	InterPro (IPR000051): SAM (and some other nucleotide) binding motif. InterPro (IPR001601): Generic methyltransferase. Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Function unclear
YP_934678.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal Peptide present. No TMH present.
YP_934679.1	Region start changed from 3485680 to 3485581 (99 bases)
YP_934680.1	part of a lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope); Specificity unclear
YP_934681.1	Similar to TREMBL:Q82SR1 (47% identity).
YP_934682.1	catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent
YP_934683.1	Putative response regulator protein,; Family membership
YP_934684.1	Region start changed from 3493365 to 3493173 (-192 bases)
YP_934685.1	Conserved hypothetical protein. Homology to Daro03003801 of Dechloromonas aromatica of 44% (gi|41722610|ref|ZP_00149605.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_934686.1	Putative cytoplasmic membrane protein, lemA, 41% identity(63% similarity) to TrEMBL;Q9FA50.TrEMBL;Q7CNK7(37% identity). Has PF04011,LemA family;IPR007156;The members of this family are related to the LemA protein P71452. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.; Conserved hypothetical protein
YP_934687.1	Conserved hypothetical membrane protein. Homology to NE0281 of Nitrosomonas europaea of 34% (trembl|Q82XI9(SRS)). No domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein
YP_934688.1	ABC transporter ATP-binding protein uup-1. InterPro: AAA ATPase superfamily Presence of SMC domain at N-terminal. Occurence of HypB/UreG nucleotide binding domain. FERM and yrdC domains are also present. Presence of uncharacterized P-loop hydralase domain. Presence of signal peptide and transmembrane helices. 61% identity and 76% similarity to Chromobacterium ABC transporter.; Family membership
YP_934689.1	Probable site-specific recombinase.; Function unclear; ORF7
YP_934690.1	Conserved hypothetical serine protease. Homology to mucD of N. europaea of 50% (trembl|Q82XA8). InterPro: Serine proteases trypsin family (IPR001254); Chymotrypsin serin protease family (S1) (IPR001314). Pfam: Trypsin. signal peptide. no TMHs; Family membership
YP_934691.1	Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) (Slt70). Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity). InterPro: SLT domain; Family membership
YP_934692.1	CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear
YP_934693.1	In part; Function unclear
YP_934694.1	Probable acetoacetate metabolism regulatory protein,; Specificity unclear
YP_934695.1	Putative two component sensor histidine kinase,; Family membership
YP_934696.1	Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership
YP_934698.1	Hypothetical protein. No known Domains/Features/Signal Peptide or TMH present. Weak Homology with hits in the database.
YP_934699.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_934700.1	Dihydrofolate reductase. catalytic activity: 5,6,7,8-tetrahydrofolate + nadp(+) = 7,8- dihydrofolate + nadph. pathway: essential step for de novo glycine and purine synthesis, dna precursor synthesis, and for the conversion of dump to dtmp. Pfam: Dihydrofolate reductase; High confidence in function and specificity
YP_934701.1	Putative orn/arg/lys decarboxylase. Homology to adiA of E. coli of 37% (sprot|ADIA_ECOLI). This family is composed of ornithine decarboxylases (ODC), arginine decarboxylases (ADC) and lysine decarboxylases (LDC), and belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase domain superfamily (fold I). These enzymes catalyse the decarboxylation of ornithine,arginine, or lysine, respectively using PLP as a co-factor. Pfam: Orn/Lys/Arg decarboxylase no signal peptide no TMHs; Specificity unclear
YP_934702.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_934703.1	Mrp protein homolog InterPro: Domain of unknown function DUF59 desulf_FeS4: desulfoferrodoxin FeS4 iron; Function unclear
YP_934704.1	Belongs to the ompa family. InterPro: Bacterial outer membrane protein; Function unclear
YP_934705.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_934706.1	Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present.; High confidence in function and specificity
YP_934707.1	Conserved hypothetical acylphosphatase. Homology to pf0283 of P. furiosus of 56% (trembl|Q8U414). Acylphosphatase specifically catalyses the hydrolysis of the carboxyl-phosphate bond of acylphosphates, its substrates including 1,3-diphosphoglycerate and carbamyl phosphate. Although its physiological role is as yet unknown it may, however, play a part in the regulation of the glycolytic pathway and pyrimidine biosynthesis. InterPro: Acylphosphatase (IPR001792). Pfam: Acylphosphatase. no signal peptide. no TMHs.; Function unclear
YP_934709.1	Conserved hypothetical secreted protein. Homology to PA1688 of Pseudomonas aeruginosa of 54% (trembl|Q9X6R1(SRS)). No domains predicted. Signal p reporting signal peptide present. NO TMH present.; Conserved hypothetical protein
YP_934710.1	DNA polymerase III alpha subunit. DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THIS DNA POLYMERASE ALSO EXHIBITS 3 TO 5 EXONUCLEASE ACTIVITY. THE ALPHA CHAIN IS THE DNA POLYMERASE (BY SIMILARITY). InterPro: DNA polymerase III alpha subunit TIGRFAM: polc: DNA polymerase III alpha subunit; High confidence in function and specificity
YP_934711.1	TREMBL:Q8XXD1: 69% identity, 76% similarity. Quinone oxidoreductase (EC 1.6.5.5) . qor, RSc2184; probable NADPH:quinone reductase, zeta-crystallin homolog oxidoreductase [EC:1.6.5.5] InterPro: Zinc-containing alcohol dehydrogenase superfamily InterPro:IPR002085; Adh_zn_family. IPR002364:QOR_zeta_crystal. Pfam:PF00107; ADH_zinc_N; 1 tdh: L-threonine 3-dehydrogenase; High confidence in function and specificity
YP_934712.1	Exported protein with C-terminal domain; Function unclear
YP_934713.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
YP_934714.1	Sporulation initiation inhibitor protein soj. INHIBITS THE INITIATION OF SPORULATION SPO0J ANTAGONIZES THIS INHIBITION. SOJ ULTIMATELY INHIBITS THE ACTIVATION (PHOSPHORYLATION) OF SPO0A. IT IS NOT REQUIRED FOR CHROMOSOME PARTITIONING. InterPro: ParA family ATPase; Function unclear
YP_934715.1	DNA helicase II (EC 3.6.1.-). HAS BOTH ATPASE AND HELICASE ACTIVITIES. UNWINDS DNA DUPLEXES WITH 3 TO 5 POLARITY WITH RESPECT TO THE BOUND STRAND AND INITIATES UNWINDING MOST EFFECTIVELY WHEN A SINGLE-STRANDED REGION IS PRESENT. INVOLVED IN THE POSTINCISION EVENTS OF NUCLEOTIDE EXCISION REPAIR AND METHYL-DIRECTED MISMATCH REPAIR. InterPro: UvrD/REP helicase.; High confidence in function and specificity
YP_934716.1	Conserved hypothetical. Homology to Daro03003519 of Dechloromonas aromatica of 32% (gi|41722969|ref|ZP_00149935.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs
YP_934717.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_934718.1	rare lipoprotein B precursor
YP_934719.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_934720.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_934721.1	Tyrosine recombinase xerD. Site-specific tyrosine recombinase which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). InterPro: Phage integrase.; High confidence in function and specificity
YP_934722.1	Putative DNA-dependent transcriptional regulator,YbaK.68% identity (75% similarity) to TrEMBL;Q748B9. TrEMBL; Q8FK79(29% identity to E.coli,ybaK).SwissProt;P37175 Has PF04073, YbaK / prolyl-tRNA synthetases associated domain;IPR007214; This domain of unknown function is found in numerous prokaryote organisms. The structure of YbaK shows a novel fold. This domain also occurs in a number of prolyl-tRNA synthetases (proRS) from prokaryotes. Thus, the domain is thought to be involved in oligo-nucleotide binding, with possible roles in recognition/discrimination or editing of prolyl-tRNA. TIGR00011; YbaK_EbsC; 1; High confidence in function and specificity
YP_934723.1	Putative trans-acting regulatory protein HvrA. Homology to hvrA of R. capsulatus of 28% (sprot|HVRA_RHOCA) IT IS A DIM-LIGHT TRANS-ACTING ACTIVATOR OF PUF AND PUH EXPRESSION BUT HAS NO EFFECT ON THE EXPRESSION OF THE PUC OPERON. IT IS RESPONSIBLE FOR REGULATING LIGHT-HARVESTING-I AND REACTION CENTER STRUCTURAL GENE EXPRESSION DIFFERENTIALLY FROM THAT OF LIGHT-HARVESTING-II EXPRESSION IN RESPONSE TO ALTERATIONS IN LIGHT. PROPER LIGHT REGULATION OF LIGHT-HARVESTING AND REACTION CENTER POLYPEPTIDE SYNTHESIS IS INDEED AN IMPORTANT PHYSIOLOGICAL TRAIT THAT ENABLES CELLS TO ADAPT TO EVER-CHANGING ENVIRONMENTAL CONDITIONS OF LIGHT INTENSITY. InterPro: H-NS histone family (IPR001801) Pfam: H-NS histone family no signal peptide no TMHs; Family membership
YP_934724.1	Dihydroneopterin aldolase (DHNA). CATALYZES THE CONVERSION OF 78-DIHYDRONEOPTERIN TO 6- HYDROXYMETHYL-78-DIHYDROPTERIN. InterPro: Dihydroneopterin aldolase TIGRFAM: folB_dom: FolB domain; High confidence in function and specificity
YP_934725.1	Conserved hypothetical membrane protein.51% identity to TrEMBL;Q6D157. Has PF02660, Domain of unknown function DUF;IPR003811; This family consists of hypothetical transmembrane proteins none of which have any known function, the aligned region is around 200 amino acids long. TMHMM2 predicts 4 TMH's. Signal peptide present, but is overlapping with the DYF,PF02660 domain. SO is the TMH's.; Conserved hypothetical protein
YP_934726.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_934727.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_934728.1	DNA primase (EC 2.7.7.-). DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis. MG010: DNA primase-related protein.; High confidence in function and specificity
YP_934729.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_934730.1	Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. Similar to trembl|Q9HY85 (74%) and to sprot|LGUL_NEIMA (70%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ProDom (PD002334): Glyoxalase I; High confidence in function and specificity
YP_934731.1	Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity
YP_934732.1	Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear
YP_934733.1	Conserved hypothetical membrane protein. Homology to ebA4352 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA4352(KEGG)). Has PF04401, Protein of unknown function (DUF540); IPR007496 DUF540; Uncharacterised bacterial integral membrane protein,possibly involved in cysteine biosynthesis. Speculated to be involved in sulphate transport. no signal peptide. 6 TMHs; Conserved hypothetical protein
YP_934734.1	Signal recognition particle protein (Fifty-four homolog) (P48). NECESSARY FOR EFFICIENT EXPORT OF EXTRA-CYTOPLASMIC PROTEINS. BINDS TO THE SIGNAL SEQUENCE WHEN IT EMERGES FROM THE RIBOSOMES.The protein has a two domain structure: the G-domain binds GTP; the M-domain binds the RNA and also binds the signal sequence. It belongs to the GTP-binding SRP family. InterPro: Signal recognition particle protein 3a0501s01: signal recognition particl Pfam: SRP54-type protein (GTPase domain); signal peptide binding domain no TMHs and signal peptide; High confidence in function and specificity
YP_934735.1	Conserved hypothetical membrane protein. Homology to ne1459 of N. europaea of 49% (trembl|Q82UM4). Pfam: Cytochrome C assembly protein. no signal peptide. 8 TMHs; Conserved hypothetical protein
YP_934736.1	Pilus assembly protein PilB is a component of the pilus biogenesis apparatus,; High confidence in function and specificity
YP_934737.1	Pilus assembly protein PilC is a component of the pilus biogenesis apparatus, similarity to pir|B35384 (50%). This apparatus is responsible for the stabilization, translocation and assembly of the monomeric pilin subunits into the pilus organelle. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial type II secretion system protein TMHMM reporting three TMH; High confidence in function and specificity
YP_934738.1	PilD is a prepilin peptidase processes the N-terminus of the prepilins. The processing is essential for the correct formation of the pseudopili of type IV bacterial protein secretion. Similar to pir|A39131 (58%). InterPro(PF01478): Prepilin cysteine protease (C20), type IV InterPro (PR00864): Prepilin cysteine protease (C20),type IV TMHMM reporting six TMH.; High confidence in function and specificity
YP_934739.1	Conserved hypothetical protein. Homology to BB0113 of B.bronchiseptica of 56% (trembl:Q7WR44). No domas predicted. No TMHs. No signal peptide.
YP_934740.1	Conserved hypothetical membrane protein, 57% identity to TrEMBL;Q7W002. Has PF04367, Protein of unknown function (DUF502);IPR007462; Predicted to be an integral membrane protein. Signal Peptide present. 1 TMHs.; Conserved hypothetical protein
YP_934741.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_934742.1	Putative response regulator,; Conserved hypothetical protein
YP_934743.1	InterPro: Guanine-specific ribonuclease N1 and T1; Family membership
YP_934744.1	Conserved hypothetical protein. Homology to XCC2280 of X.campestris of 33% (trembl:Q8P8G2). No domains predicted. No signal Peptide present. No TMH present.
YP_934745.1	Putative small heat shock protein. Homology to hsp18 of C. acetobutylicum of 35% (sprot|HS18_CLOAB) InterPro: Heat shock hsp20 (alpha crystallin) proteins family (IPR002068) Pfam: Hsp20/alpa cystallin family no signal peptide no TMHs; Function unclear
YP_934746.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_934747.1	Conserved hypothetical secreted protein. Homology to ebA4328 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA4328(KEGG)). no domains predicted. signal peptide. TMH in signal peptide
YP_934748.1	Esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active coa thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q8UET3 (39% identity); TREMBL:Q988H2 (38% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase Pfam (PF00501): AMP-binding enzyme.; High confidence in function and specificity
YP_934749.1	Asparagine synthase catalyze the conversion of aspartate to asparagine. Similar to trembl|Q82VG1 (45%) and to trembl|Q7USD1 (27%). Pfam (PF00733): Asparagine synthase; Family membership
YP_934750.1	Diaminopimelate decarboxylase,; Specificity unclear
YP_934751.1	Conserved hypothetical secreted protein. Homolgy to ne2159 of N. europaea of 33% (trembl|Q82SY7). InterPro: TPR repeat (IPR001440). Pfam: TPR domain signal peptide. TMH in signal peptide; Conserved hypothetical protein
YP_934752.1	Conserved hypothetical protein. Homology to ne2161 of N. europaea of 45% (trembl|Q82SY5). Interpro: Esterase/lipase/thioesterase family. no damians predicted. no signal peptide. no TMHs.
YP_934753.1	Probable Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase). TREMBL:Q82SY4:40% identity, 57% similarity. InterPro:IPR000379; Ser_estrs Pfam:UPF0007:Uncharacterized protein family UPF000 thiE: thiamine-phosphate pyrophosphorylas No transmembrane helices; Function unclear
YP_934754.1	Conserved hypothetical protein. Homology to ne2163 of N. europaea of 42% (trembl|Q82SY3). Pfam: Poshpopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. no signal peptide. no TMHS
YP_934755.1	Conserved hypothetical protein. Homology to Mmc102002678 of Magnetococcus sp. MC-1 of 44% (gi|48831833|ref|ZP_00288884.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
YP_934756.1	May be related to biosynthesos of cell surface carbohydrates / polysaccharides.
YP_934757.1	Specificity unclear
YP_934758.1	Conserved hypothetical polysaccharide biosynthesis protein, related to GumJ. Homology to ebA4295 of Azoarcus sp. EbN1 of 42%. Pfam: Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis SP5B_BACSU, which is involved in spore cortex biosynthesis. No signal peptide. 10 TMHs.; Family membership
YP_934759.1	Similar to putative exopolysaccharide polymerization protein PssK; Family membership
YP_934760.1	InterPro: Glycosyl transferase family 2; Function unclear
YP_934761.1	InterPro: Glycosyl transferase family 2; Specificity unclear
YP_934762.1	InterPro: Glycosyl transferase family 2; Specificity unclear
YP_934763.1	Putative glycosyl transferase ypjH (EC 2.-.-.-). TIGR00022: conserved hypothetical pro; Specificity unclear
YP_934764.1	Hypothetical glycosyl transferase MJ1607 (EC 2.-.-.-). InterPro: Glycosyl transferases group 1; Specificity unclear
YP_934765.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. signal peptide present.
YP_934766.1	Conserved hypothetical secreted protein. Homology RB4730 of Rhodopirellula baltica of 36% (trembl|Q7US36). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein
YP_934767.1	Similar to a gene annotaed to encode a dolichol-phosphate mannosyltransferase, a glycosyltransferase that transfers a suga directly to a lipid carrier. InterPro: Glycosyl transferase family 2; Specificity unclear
YP_934768.1	Conserved hypothetical polysacchacride deacetylase. Homology to N. europaea of N. europaea of 54% (trembl|Q82W49(SRS)). This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast, and endoxylanases which hydrolyses glucosidic bonds in xylan. InterPro:IPR002509; Polysac_deacet. Pfam:PF01522; Polysacc_deac_1; 1. no TMHs no signal peptide; Conserved hypothetical protein
YP_934769.1	Conserved hypothetical membrane protein. Homology to RferDRAFT_3275 of Rhodoferax ferrireducens of 46%. Pfam: O-Antigen Polymerase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. The enzyme is coded for by the gene wzy which is part of the O-antigen gene cluster. No signal peptide. 9 TMHs.; Family membership
YP_934770.1	InterPro: Glycosyl transferases group 1; Specificity unclear
YP_934771.1	[EC:1.1.1.132] , UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).,UDP-glucose/GDP-mannose dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; High confidence in function and specificity
YP_934772.1	InterPro: Glycosyl transferases group 1; Specificity unclear
YP_934773.1	Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. Similar to trembl|Q7USD1 (35%) and to sprot|ASNB_BACSU (30%). Pfam (PF00310): Glutamine amidotransferase class-II Pfam (PF00733): Asparagine synthase; Specificity unclear
YP_934774.1	InterPro: Glycosyl transferases group 1; Specificity unclear
YP_934775.1	Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. Similar to trembl|Q81ZU7 (64%) and to trembl|Q7USD1 (37%). Pfam (PF00310): Glutamine amidotransferase class-II Pfam (PF00733): Asparagine synthase; Specificity unclear
YP_934776.1	InterPro: Glycosyl transferases group 1; Specificity unclear
YP_934777.1	Conserved hypothetical membrane protein. Homology to NE1797 of Nitrosomonas europaea of 33% (trembl|Q82TS7(SRS)). no domains predicted. signal peptide. 7 TMHs; Conserved hypothetical protein
YP_934778.1	Possibly related to cell surface polysaccharide biosynthesis, due to the presence of the gene in a polysaccharide synthesis gene cluster.; Function unclear
YP_934779.1	62% Myb_DNA_binding.IPR002509; Polysac_deacet. Pfam:PF01522; Polysacc_deac_1; 1.
YP_934780.1	UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity
YP_934781.1	General secretion pathway protein A. Involved in a general secretion pathway (GSP) for the export of proteins. InterPro: AAA ATPase superfamily POssibly related to the biosynthesis of cell surface polysaccharide due to the presence of the gene in a polysaccharide synthesis gene cluster.; High confidence in function and specificity
YP_934783.1	Putative tyrosine-protein kinase (EC 2.7.10.1).; High confidence in function and specificity
YP_934784.1	Conserved hypothetical polysaccharide chain length determinant protein. Homology to ebA4249 of Azoarcus sp. EbN1 of 66%. No signal peptide. 3 TMHS. Pfam: Wzz = Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases such as ETK_ECOLI.; Family membership
YP_934785.1	Conserved hypothetical polysaccharid export protein. Homology to wza of Azoarcus sp. EbN1 of 80%. Pfam: Polysaccharide biosynthesis/export protein. This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export. No TMHs. Signal peptide present., ,; Family membership
YP_934786.1	Conserved hypothetical protein. Homology to ne2229 of N. europaea of 38% (trembl|Q82SS7). no domains predicted. no signal peptide. no TMHs.
YP_934787.1	Conserved hypothetical secreted protein. Homology to NE2243 of Nitrosomonas europaea of 43% (trembl|Q82SR4(SRS). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein
YP_934788.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q82SR3 (67% identity); TREMBL:Q92NU9 (48% identity); SWISSPROT:Q58206 (45% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership
YP_934789.1	Conserved hypothetical secreted protein. Homology to NE2245 of Nitrosomonas europaea of 51% (tremble:Q82SR2). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_934790.1	Putative exonuclease of the beta-lactamase fold involved in RNA processing, N-terminal fragment.; Family membership
YP_934791.1	Putative exonuclease of the beta-lactamase fold involved in RNA processing, C-terminal fragment; Family membership
YP_934792.1	Major outer membrane protein P.IB precursor (Protein IB) (PIB) (Porin). Serves as a slightly cation selective porin. InterPro: General diffusion Gram-negative porins L12: ribosomal protein L7/L12; Function unclear
YP_934793.1	Outer membrane porin protein 32 precursor (OMP32). Forms anion selective channels. InterPro: General diffusion Gram-negative porins 2A0310: amino acid permease (yeast); Function unclear
YP_934794.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_934795.1	SCO2 protein homolog mitochondrial precursor. Acts as a copper chaperone transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2). InterPro: SCO1/SenC TREMBL:Q8Y2G3: 56% identity, 74% similarity InterPro:IPR003782; SCO1_SenC. Pfam: PF02630; SCO1-SenC dsbE: periplasmic protein thiol:disulf Presence of signal peptide (SignalP predicted) No TMH's present; Family membership
YP_934796.1	converts protoheme IX and farnesyl diphosphate to heme O
YP_934797.1	Putative Cytochrome aa3 oxidase assembly protein,42% Identity to TrEMBL;Q7P0G1, Q62F60. Has PF02628,Cytochrome oxidase assembly protein; IPR003780,COX15_CtaA; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast (P40086).
YP_934798.1	Conserved hypothetical membrane protein. Homology to RS03338 of Ralstonia solanacearum of 36% (trembl|Q8Y2G6(SRS)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein
YP_934799.1	Conserved hypothetical secreted protein. Homology to NE1012 of N.europaea of 31% (tremble:Q82VQ4). No domains predicted. Signal peptide present. No TMHs; Conserved hypothetical protein
YP_934800.1	Conserved hypothetical membrane protein. Homology to rs0336 of R. solanacearum of 53% (trembl|Q8Y2G8(SRS)). no domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein
YP_934801.1	Cytochrome c oxidase polypeptide III Subunits I II and III form the functional core of the enzyme complex. InterPro: Cytochrome c oxidase subunit III; High confidence in function and specificity
YP_934802.1	Conserved hypothetical membrane protein, 73% similarity to TrEMBL;Q7WE10,Putative membrane protein [BB4828] [Bordetella bronchiseptica(Alcaligenes bronchisepticus). no signal peptide. 1 TMHs
YP_934803.1	involved in the insertion of copper into subunit I of cytochrome C oxidase
YP_934804.1	Conserved hypothetical membrane protein. Homology to rsc0364 of R. solanacearum of 42% (trembl|Q8Y2H2) no domains predicted no signal peptide 1 TMHs; Conserved hypothetical protein
YP_934805.1	Probable cytochrome c oxidase, subunit I (EC 1.9.3.1) (Cytochrome AA3 subunit 1). Homology to coxA of B. japonicum of 55% (sprot|COX1_BRAJA(SRS)) cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. subunits 1- 3 form the functional core of the enzyme complex. co i is the catalytic subunit of the enzyme. electrons originating in cytochrome c are transferred via the copper a center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper b. Pfam: Cytochrome c and quinol oxidase polypeptide no signal peptide 12 TMHs; High confidence in function and specificity
YP_934806.1	Conserved hypothetical cytochrome c oxidase,subunit II. Homology to bb4831 of B. bronchiseptica of 60% (trembl|Q7WE07). SUBUNIT I AND II FORM THE FUNCTIONAL CORE OF THE ENZYME COMPLEX. ELECTRONS ORIGINATING IN CYTOCHROME C ARE TRANSFERRED VIA HEME A AND CU(A) TO THE BINUCLEAR CENTER FORMED BY HEME A3 AND CU(B). InterPro: Cytochrome c oxidase subunit II (IPR002429); cytochrome c, class IC (IPR008168); cytochrome, class I (IPR003088); Cu(A) centre of cytochrome coxidase, subunit II and nitrous oxide reductase (IPR001505) Pfam: Cytochrome c oxidase subunit II, transmembran domain; cytochrome c oxidase subunit II,periplasmic domain; cytochrome c Tirgfam: ccoP: cytochrome c oxidase cbb3-type signal peptide 2 TMHs; Conserved hypothetical protein
YP_934807.1	ADP-heptose synthase (EC 2.7.-.-). cyt_tran_rel: cytidyltransferase-related; High confidence in function and specificity
YP_934808.1	Conserved hypothetical Na+-dependent phosphate transporter protein. Homolg to Bacteroides thetaiotaomicron. TREMBL:Q8A4R9 InterPro:IPR003841; Na/Pi_cotranspt.IPR004633; NaPi_cotransptII. Pfam:PF02690; Na_Pi_cotrans; 1. SignalP: present TMhelix:8 present. InterPro: Na+/Pi-cotransporter NaPi_cotrn_rel: Na/Pi cotransporter II Hypothetical protein yjbB.; Specificity unclear
YP_934809.1	Probable coenzyme A transferase. Homology to cat1 of C. kluyveri of 51% (sprot|CAT1_CLOKL). Pfam: Acetyl-CoA hydrolase/transferase no signal peptide no TMHs tal_mycobact: transaldolase; Family membership
YP_934810.1	Putative MerR-family transcriptional regulator. InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif. h_aconitase: homoaconitase
YP_934811.1	Conserved hypothetical amine oxidoreductase. Homology to atu1977 of A. tumefaciens of 47% (trembl|Q8UDY9). Pfam: Flavine containing amine oxidoreductase no signal peptide 1 TMHs; Conserved hypothetical protein
YP_934812.1	Conserved hypothetical protein. Homology to CV3225 of C.violaceum of 50% (trembl:Q7NPR5). Has PF07103,Protein of unknown function (DUF1365);IPR010775 ;This family consists of several bacterial and plant proteins of around 250 residues in length. The function of this family is unknown. No signal peptide or TMH present.
YP_934813.1	Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) (Cyclopropane fatty acid synthase) (CFA synthase). InterPro: Cyclopropane-fatty-acyl-phospholipid synthase; High confidence in function and specificity
YP_934814.1	Conserved hypothetical secreted protein. Homology to PP2729 of P.putida of 36% (tremble:Q88JC0). No domains predicted. Signal peptide present. NO TMH reported present.; Conserved hypothetical protein
YP_934815.1	Integral membrane protein.Belongs to the Na/galactoside symporter family. 20% MFS.IPR001927; Na/Gal_symport. TIGRFAMs:TIGR00792; gph; 1. TMHelix:12.; Function unclear
YP_934816.1	Conserved hypothetical secreted protein. Homology to PP2730 of P.putida of 48% (tremble:Q88JB9). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_934817.1	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q92PV6 (39 % identity); TREMBL:Q88JB2 (33% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear
YP_934818.1	Conserved hypothetical protein. Homology to CV3228 of C.violaceum of 40% (trembl:Q7NT36). No domains predicted. No Signal peptide present. No TMH reported present.
YP_934819.1	TREMBL:Q881C6:69% identity; 83% similarity. Alcohol dehydrogenase (EC: 1.1.1.1) (ADH) catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD: Ethanol + NAD = Acetaldehyde + NADH Protein yhdH. InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N; FAD binding domain InterPro: Zinc-containing alcohol dehydrogenase superfamily TIGRFAM:tdh: L-threonine 3-dehydrogenase; High confidence in function and specificity
YP_934820.1	ATP-dependent DNA helicase recQ (EC 3.6.1.-). INVOLVED IN THE RECF RECOMBINATION PATHWAY; ITS GENE EXPRESSION IS UNDER THE REGULATION OF THE SOS SYSTEM. IT IS A DNA HELICASE. recq: ATP-dependent DNA helicase RecQ.; High confidence in function and specificity
YP_934821.1	Peptidyl-prolyl cis-trans isomerase. Homology to fkbP of N. meningitidis of 69% (sprot|FKBP_NEIMB) PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase)(IPR001179) Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase no signal peptide no TMHs; High confidence in function and specificity
YP_934822.1	Putative peptide methionine sulfoxide reductase. Homology to msrA of E. coli of 37% (SWISSPROT:MSRA_ECOLI) Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). InterPro: Peptide methionine sulfoxide reductase (IPR002569) Pfam: Peptide methionine sulfoxide reductase Tigrfam: msrA: peptide methionine sulfoxide reductase no signal peptide no TMHs; Family membership
YP_934823.1	Conserved hypothetical membrane protein. Homology to rsc2383 of R. solanacearum of 31% (trembl|Q8XWT7(SRS)). no domains predicted .no signal peptide. 1 TMHs; Conserved hypothetical protein
YP_934824.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_934825.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_934826.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
YP_934827.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_934828.1	Phosphoglycolate phosphatase 1 (EC 3.1.3.18) (PGP 1). TREMBL:Q7W391: 50% identity, 65% similarity. catalytic activity: 2-phosphoglycolate + h(2)o = glycolate + phosphate. similarity:belongs to the cbby/cbbz/gph/yieh family. InterPro: Haloacid dehalogenase/epoxide hydrolase family InterPro:IPR006402; HAD-SF-IA-v3. IPR006439; HAD_SF_A_v1. IPR005833; Hlgnase/hydrlase. Pfam PF00702; Hydrolase; 1. PRINTS PR00413; HADHALOGNASE. TIGRFAMs:TIGR01549; HAD-SF-IA-v1; 1 hstdl_phs_rel: histidinol phosphatase-r; High confidence in function and specificity
YP_934829.1	Ribulose-phosphate 3-epimerase(also known as pentose-5-phosphate 3-epimerase, PPE or Rpe), is the enzyme that converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. 71%Ribul_P_3_epim. Pfam:PF00834; Ribul_P_3_epim; 1. TIGRFAMs:TIGR01163; rpe; 1.; High confidence in function and specificity
YP_934830.1	General secretion pathway protein E,; Specificity unclear
YP_934831.1	Probable 35-cyclic-nucleotide phosphodiesterase precursor (EC 3.1.4.17) (PDEase) (3:5-CNP). TREMBL:Q8ZD92:28% identity, 47% similarity InterPro; IPR001279; Blactmase-like. IPR000396; Pdiesterase2. Pfam: PF00753; Lactamase_B No transmembrane helices TIGR00010: deoxyribonuclease TatD fami; Function unclear
YP_934832.1	Conserved hypothetical protein which may be involved into signal transduction processes. Important Domain: Pfam:PF00498 FHA domain. The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for phosphothreonine-containing epitopes but will also recognise phosphotyrosine with relatively high affinity. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors,RNA-binding proteins and metabolic enzymes.
YP_934833.1	Putative phosphoprotein phosphatase,; Family membership
YP_934834.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
YP_934835.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_934836.1	Conserved hypothetical protein. Homology to BP2542 of B.pertussis of 50% (trembl:Q7VVU4). No domains predicted. No signal peptide. No TMHs
YP_934837.1	In Pseudomonas aeruginosa, FimV is probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (26%). Pfam (PF05489): Phage Tail Protein X SignalP reporting Signal peptide; Function unclear
YP_934838.1	Conserved hypothetical protein,ybgI, 48% identity(67% similarity) to SwissProt;P75743(E.coli)SP|Q8XFW7. SwissProt;Q8XVA0(58% identity)Ralstonia solanacearum. TrEMBL;Q82UH6(53% identity)Nitrosomonas europaea. Has PF01784, NIF3 (NGG1p interacting factor 3);IPR002678, DUF34; This family contains several NIF3 (NGG1p interacting factor 3) protein homologues. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.
YP_934839.1	Probable serine protease AlgW. Homology to algW of P. aeruginosa of 48% (trembl|Q51374). InterPro: Serine proteases trypsin family (IPR001254); PDZ domain (Also known as DHR or GLGF) (IPR001478); HtrA/DegQ protease family (IPR001940) Pfam: PDZ domain (Also known as DHR or GLGF); Trypsin no signal peptide 1 TMH; High confidence in function and specificity
YP_934840.1	Sec-independent protein translocase tatC. Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N and C termini of TatC or cpTatC are exposed to the cytoplasmic 2a6401s02: Sec-independent periplasmic Pfam: MttB family UPF0032 propable 6 TMHs, no signal peptide; High confidence in function and specificity
YP_934841.1	Sec-independent protein translocase tatB. Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export. no signal peptide probable TMHs: 1 TatB is essential for the secretion of these specific proteins, and forms a scaffold upon which TatC assembles in the membrane. Deletion studies have shown that it is crucial in the forming of the TAT complex, and is therefore necessary for the correct working of the system.; High confidence in function and specificity
YP_934842.1	TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
YP_934843.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_934844.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
YP_934845.1	PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers
YP_934846.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_934847.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_934848.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_934849.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
YP_934850.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_934851.1	Similar to phage protein P7. InterPro: SLT domain; Family membership
YP_934852.1	Putative signaling protein in beta-lactamase regulation. AMPD seems not to act as a direct sensor for beta-lactams. It hydrolyzes 16-anhydro-N-acetylmuramoyl-L-alanyl-D-3glutamyl-meso- diaminopimelic acid to the tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate (By similarity), TREMBL:Q8KRJ4 (63% identity); SWISSPROT:P82974 (60% identity). Pfam (PF01510): N-acetylmuramoyl-L-alanine amidase.; High confidence in function and specificity
YP_934853.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:O59091 (37% identity); TREMBL:Q7NDM5 (40% identity). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; High confidence in function and specificity
YP_934854.1	Similar to hypothetical protein GSU1500 of Geobacter sulfurreducens PCA (16%). TMHMM2 reporting one TMhelix. Sigcleave reporting one SignalPeptide. Coils2 reporting coiled coil region
YP_934855.1	In Myxococcus xanthus pilI are co-transcribed with pilH an ABC transporter homologue required for type IV pilus biogenesis and social gliding. pilI appear to be functionally related to pilH. Similar to membrane protein of Geobacter sulfurreducens PCA (14%) and weak; Conserved hypothetical protein
YP_934856.1	PilB encodes for a 14.2 kDa polypeptide showing similarity to FimF, a component of type I fimbriae of E. coli. It may be part of the pilus assembly complex or the pilus itself. (Reference: Doerr et al., 1998 Molecular Microbiology); Specificity unclear
YP_934857.1	PilA encodes an unusually short (6.4 kDa)putative pilin precursor showing 100% sequence identity to the conserved N-terminus of the Pseudomonas aeruginosa type IV pilin. (Reference: Doerr et al., 1998 Molecular Microbiology); High confidence in function and specificity
YP_934858.1	Two component system response regulator,; High confidence in function and specificity
YP_934859.1	Two component system sensor protein,; High confidence in function and specificity
YP_934860.1	Hypothetical membrane protein. No real homology of the entire protein to the data bank. no domains predicted no signal peptide 1TMH
YP_934861.1	catalyzes the transfer of an amino moiety
YP_934862.1	isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway
YP_934863.1	L-fuculose phosphate aldolase(L-fuculose-1-phosphate aldolase). Involved in the fucose metabolism catalyzing the third step of the pathway, L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde. 41% Aldolase_II_N.IPR004782; FucA. Pfam:PF00596; Aldolase_II; 1. TIGRFAMs:TIGR01086; fucA; 1.; High confidence in function and specificity
YP_934864.1	Putative 2-hydroxy-3-oxopropionate reductase Homology to glxR of E. coli of 39% (SWISSPROT:GLXR_ECOLI) Activity:- (R)-glycerate + NAD(P)(+) = 2-hydroxy-3-oxopropanoate + NAD(P)H. InterPro: 3-hydroyisobutyrate dehydrogenase (IPR002204) Pfam: Nad binding domain of 6-phosphoglucanate dehydrogenase (PF03446) Tigrfam: gnd_rel: 6-phosphoglucante no signal peptide no TMHs; Family membership
YP_934865.1	Probable 2-hydroxy-3-oxopropionate reductase Homology to glxR of E. coli of 46% (SWISSPROT:GLXR_ECOLI) Activity:- (R)-glycerate + NAD(P)(+) = 2-hydroxy-3-oxopropanoate + NAD(P)H. InterPro: 3-hydroyisobutyrate dehydrogenase (IPR002204) Pfam: Nad binding domain of 6-phosphoglucanate dehydrogenase (PF03446) Tigrfam: gnd_rel: 6-phosphoglucante no signal peptide no TMHs 0; High confidence in function and specificity
YP_934866.1	The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership
YP_934867.1	Putative pyrophosphorylase modD (EC 2.4.2.-). InterPro: Quinolinate phosphoribosyl transferase; Specificity unclear
YP_934868.1	Conserved hypothetical protein. Homology to rpa3088 of R. palustris of 65% (tremblnew|CAE28529). Pfam: Dinitrogenase iron-molybdenum cofactor. no signal peptide. no TMHs.
YP_934869.1	Putative NifZ Protein homolog, shares 45% similarity to SwissProt:P46040, NifZ protein entry. Has PF04319:IPR007415:NifZ domain;This short protein is found in the nif (nitrogen fixation) operon. Its function is unknown but is probably involved in nitrogen fixation or regulating some component of this process. This 75 residue region is presumed to be a domain. It is found in isolation in some members and in the amino terminal half of the longer NifZ proteins. No Signal peptide present. No TMH Present.; High confidence in function and specificity
YP_934870.1	Probable ferredoxin 2fe-2s protein. Homology to fer2 of C. pasteruianum of 43% (sprot|FER2_CLOPA). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. no signal peptide no TMHs; Family membership
YP_934871.1	Pirin-like protein. TREMBL:8Y1Z6: 68% identity, 80% similarity InterPro: DUF209 InterPro:IPR008778; Pirin_C. IPR003829; Pirin_N. Pfam :PF02678; Pirin; 1. PF05726; Pirin_C TIGR00292: thiazole biosynthesis enzyme No signal peptide (Signal P predicted). No transmembrane helices (TMHMM predicted).; Specificity unclear
YP_934872.1	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP (By similarity). Entry name :- SWISSPROT:ACPD_ECOLI InterPro:-IPR003680; NADHdh_2. Pfam:- PF02525; Flavodoxin_2; 1. Identities = 97/180 (53%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_934873.1	Putative transcriptional regulator, LysR family,; High confidence in function and specificity
YP_934874.1	Disulfide bond formation protein B. Homology to dsdB of B. cepacia of 38% (BAA11858). Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the dsbA protein (By similarity). InterPro: Disulfide bond formation protein DsbB (IPR3752). Pfam: Disulfide bond formation protein DsbB signal peptide probable 3 to 4 TMHs; Family membership
YP_934875.1	Conserved hypothetical protein. Homology to cv1788 of C. violaceum of 33% (trembl|Q7NX41). no domains predicted. no signal peptide. no TMHS.
YP_934876.1	Homolog to the hypothetical protein ygaP from E.coli. SWISSPROT:YGAP_ECOLI InterPro: IPR001763; Rhodanese-like. Pfam: PF00581; Rhodanese; 1. TMhelix:2 present.; Function unclear
YP_934877.1	AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q8KAV4 (43% identity); SWISSPROT:P25197 (23% identity). InterPro (IPR001036): Acriflavin resistance protein. PFam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 11 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear
YP_934878.1	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family. SignalP predicting signal peptide. TC (2.A.6.1): The Heavy Metal Efflux (HME) Family.; Family membership
YP_934879.1	Conserved hypothetical protein. Homology to Bcep18194_A5800 of Burkholderia sp. 383 of 53%. Pfam: CbiX. The function of CbiX is uncertain, however it is found in cobalamin biosynthesis operons and so may have a related function. Some CbiX proteins contain a striking histidine-rich region at their C-terminus, which suggests that it might be involved in metal chelation. No signal peptide. No TMHs.
YP_934880.1	Region start changed from 3713308 to 3713122 (-186 bases)
YP_934881.1	Probable metallo betalactamase related protein with 47% identity and 65% similarity (TREMBL:Q82SI4). Pfam: Chitin synthetase, SOR/SNZ family, Thiolase N-terminal domain, phosphotyrosine interaction domain. TMHMM predicted transmembrane helix.; Function unclear
YP_934882.1	Region start changed from 3714581 to 3714479 (102 bases)
YP_934883.1	Hypothetical signaling protein
YP_934884.1	Putative two-component system regulatory protein,weak similarity to SWISSPROT: sprot|RCP1_SYNY3 (32% Synechocystis sp., response regulator Rcp1 ) InterPro: IPR001789 Response_reg. Pfam: PF00072 response_reg. SMART: SM00448 REC. Response regulator rcp1. FORMS A TWO-COMPONENT SYSTEM WITH CPH1 IN WHICH IT ACTS AS RECEIVER SUBSTRATE.; Family membership
YP_934885.1	Putative two-component system sensor protein, weak similarity to SWISSPROT: sprot|PHY1_SYNY3 (10% Synechocystis sp., Cph1) InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR003661 His_kinA_N. IPR005467 His_kinase. IPR003660 HAMP. IPR000014 PAS_domain. IPR001610 PAC motif. Pfam: PF00672 HAMP. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS domain. PF00785 PAC motif SMART: SM00304 HAMP. SM00387 HATPase_c. SM00388 HisKA. SM00091 PAS. SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices. Phytochrome-like protein cph1 (EC 2.7.3.-) (Light-regulated histidine kinase 1) (Bacteriophytochrome cph1). REGULATORY PHOTORECEPTOR WHICH EXISTS IN TWO FORMS THAT ARE REVERSIBLY INTERCONVERTIBLE BY LIGHT: THE R FORM THAT ABSORBS MAXIMALLY IN THE RED REGION OF THE SPECTRUM AND THE FR FORM THAT ABSORBS MAXIMALLY IN THE FAR-RED REGION. HAS ALSO A SLIGHT BLUE SHIFT FOR THE FAR-RED MAXIMUM. FORMS A TWO-COMPONENT SYSTEM WITH THE RCP1 RESPONSE REGULATOR.; Conserved hypothetical protein
YP_934886.1	Putative aliphatic sulfonates binding protein precursor.PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALIPHATIC SULFONATES. PUTATIVE BINDING PROTEIN. 22% SBP_bac_3. SMART: SM00062; PBPb; 1.; Specificity unclear
YP_934887.1	Single-strand binding protein (Helix-destabilizing protein). This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair (By similarity).; High confidence in function and specificity
YP_934888.1	Hypothetical transport protein yajR. InterPro: General substrate transporters 2_A_01_02: Multidrug resistance protein; Specificity unclear
YP_934889.1	UvrABC system protein A (UvrA protein) . The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB the uvrA molecules dissociate (By similarity). InterPro: Excinuclease ABC A subunit uvra: excinuclease ABC A subunit.; High confidence in function and specificity
YP_934890.1	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs
YP_934891.1	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity
YP_934892.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_934893.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_934894.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_934895.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_934896.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_934897.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_934898.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_934899.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_934900.1	late assembly protein
YP_934901.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_934902.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_934903.1	binds 5S rRNA along with protein L5 and L25
YP_934904.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_934905.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_934906.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_934907.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_934908.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_934909.1	50S ribosomal protein L14.; High confidence in function and specificity
YP_934910.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_934911.1	one of the stabilizing components for the large ribosomal subunit
YP_934912.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_934913.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_934914.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_934915.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_934916.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_934917.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_934918.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_934919.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_934920.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_934921.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_934922.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_934923.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_934924.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_934925.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_934926.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_934927.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_934928.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_934929.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_934930.1	binds directly to 23S ribosomal RNA
YP_934931.1	Modulates Rho-dependent transcription termination
YP_934932.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_934933.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_934934.1	D-lactate dehydrogenase. Homology to dld of Mus musculus of 52% (trembl|Q8CIV4) CATALYZE THE STEREOSPECIFIC OXIDATION OF D-LACTATE TO PYRUVATE. InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase, N-terminal (IPR006093) Pfam: FAD binding damian; FAD linked oxidases, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership
YP_934935.1	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
YP_934936.1	Conserved hypothetical membrane protein. Similar to TREMBL:Q82Y44 (38% identity); TREMBL:Q7NWG1 (37% identity). TMHMM reporting four transmembrane helices. signal peptide; Conserved hypothetical protein
YP_934937.1	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank Pfam: CobQ/CobB/MinD/ParA nucleotide binding domain no signal peptide no TMHs
YP_934938.1	Probable DNA-binding response regulator, LuxR family,; Specificity unclear
YP_934939.1	Conserved hypothetical secreted protein. Homology to ebA3798 of Azoarcus sp. EbN1 of 42% (gnl|keqq|eba:ebA3798(KEGG)). Pfam: DUF534. This is a family of putative secreted proteins of unknown function. signal peptide. no TMHs.; Conserved hypothetical protein
YP_934940.1	Putative virulence regulator protein,ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR003660; HAMP. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. SM00448; REC. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Specificity unclear
YP_934941.1	conserved hypothetical protein. Homology to ebB122 of Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebB122(KEGG)). No domains predicted. NO signal peptide present. No TMH present.
YP_934942.1	Conserved hypothetical protein. Homology to pa1188 of P. aeruginosa of 40% (trembl|Q9I4F0). InterPro: CAIB/BAIF family (IPR003673). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. TIGR00106: conserved hypothetical protein
YP_934943.1	Phenylacetate-coenzyme A ligase (Phenylacetyl-CoA ligase) (PA-CoA ligase). CATALYZES THE ACTIVATION OF PHENYLACETIC ACID TO PHENYLACETYL-COA. InterPro: AMP-dependent synthetase and ligase; Function unclear
YP_934944.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7WQU7 (73%) and to trembl|Q89HM3 (54%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear
YP_934945.1	Conserved hypothetical ABC-type branched-chain amino acid transport systems, periplasmic component. Homology to Raeut03002728 of R. eutropha of 58% (gi|45519901|ref|ZP_00171452.1|(NCBI ENTREZ)). Pfam: Receptor family ligand binding region. This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure. Signal peptide present. TMH in signal peptide.; Family membership
YP_934946.1	Putative branched-chain amino acid transport permease. Homology to livM of E. coli of 27%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: Branched-chain amino acid transport system no signal peptide probalbe 10 TMHs; Specificity unclear
YP_934947.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q881A7 (65%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting eight Tmhelix. SignalP reporting Signal peptide.; Specificity unclear
YP_934948.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q881A6 (55%), to sprot|BRAF_PSEAE (34%) and to sprot|LIVG_ECOLI (33%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear
YP_934949.1	Function:-Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates cheY, the response regulator involved in flagellar movement and chemotaxis. Activity:- ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA Entry name SWISSPROT:ACSA_ECOLI InterPro:- IPR000873; AMP-bind. Pfam:- PF00501; AMP-binding; 1. Identities = 114/506 (22%) Number of predicted TMHs: 0; Family membership
YP_934950.1	Conserved hypothetical secreted protein. Homology to Daro03001225 of Dechloromonas aromatica of 43% (gi|46141136|ref|ZP_00153001.2|(NBCI ENTREZ)). Pfam: Protein of unknown function. signal peptide. TMH in signal peptide
YP_934951.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_934952.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
YP_934953.1	Phosphomethylpyrimidine kinase (HMP-phosphate kinase) (HMP-P kinase). catalyzes the phosphorylation of hmp-p to hmp-pp (by similarity) TIGRFAM: HMP-P_kinase: phosphomethylpyrimidine kinase; Specificity unclear
YP_934954.1	High confidence in function and specificity
YP_934955.1	Pilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilG protein. IS INVOLVED IN PILUS BIOSYNTHESIS AND TWITCHING MOTILITY. MAY ACT AS A SINGLE-DOMAIN RESPONSE REGULATOR WHOSE FUNCTION MAY BE TO RECEIVE A CERTAIN ENVIRONMENTAL SIGNAL(S) AND THEN TRANSDUCE THAT SIGNAL TO THE PILUS ASSEMBLY MACHINERY VIA SPECIFIC PROTEIN-PROTEIN INTERACTIONS.; High confidence in function and specificity
YP_934956.1	Pilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilH protein. MAY BE A PART OF A SIGNAL-TRANSDUCTION SYSTEM THAT REGULATES TWITCHING MOTILITY BY CONTROLLING PILUS FUNCTION (EXTENSION AND RETRACTION).; High confidence in function and specificity
YP_934957.1	Probable pilus biogenesis protein, CheW. Protein pilI. MAY BE A PART OF A SIGNAL-TRANSDUCTION SYSTEM THAT REGULATES TWITCHING MOTILITY BY CONTROLLING PILUS FUNCTION (EXTENSION AND RETRACTION). InterPro: CheW-like domain; High confidence in function and specificity
YP_934958.1	Probable pilus biogenesis protein,; High confidence in function and specificity
YP_934959.1	Putative pilus biogenese protein, ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. IPR001789; Response_reg. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. PF00072; Response_reg. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. SM00448; REC. HTH reporting nucleic acid binding motif; Function unclear
YP_934960.1	DNA photolyase (Photoreactivating enzyme). THIS ENZYME CATALYZES THE LIGHT-DEPENDENT MONOMERIZATION (300-600 NM) OF CYCLOBUTYL PYRIMIDINE DIMERS (IN CIS-SYN CONFIGURATION) WHICH ARE FORMED BETWEEN ADJACENT BASES ON THE SAME DNA STRAND UPON EXPOSURE TO ULTRAVIOLET RADIATION. TIGRFAM: phr2: deoxyribodipyrimidine photolyase.; High confidence in function and specificity
YP_934961.1	Transcriptional regulator,; Specificity unclear
YP_934962.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_934963.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
YP_934964.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_934965.1	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
YP_934966.1	Conserved hypothetical protein. Homology to vc0458 of V. clholerae of 48% (sprot:Y458_VIBCH). InterPro: DUF167 (IPR003748). Pfam: Uncharacterized ACR, YGGU family, COF1872. no signal peptide. no TMHs
YP_934967.1	Conserved hypothetical YGGT-family protein. Homology to ne0394 of N. europae of 37% (trembl|Q82X94). This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown. InterPro: YGGT family (IPR003425). Pfam: YGGT family. no signal peptide. 5 TMHs.; Conserved hypothetical protein
YP_934968.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_934969.1	Concerved hypothetical protein. Homology to PA0394 of P. aeruginosa of 65% (sprot|Y394_PSEAE). InterPro: Uncharacterized pyridoxal-5-phosphate dependent enzyme family UPF0001 (IPR001608). Pfam: Uncharacterized protein family UPF0001. Tigrfam: TIGR00044: conserved hypothetical protein. no signal peptide. no TMHs
YP_934970.1	Tfp retraction protein PilT, involved in the twitching motility mechanism together with PilU,; High confidence in function and specificity
YP_934971.1	Tfp retraction protein PilU is involved in the Twitching Motility mechanism,; High confidence in function and specificity
YP_934972.1	Probable vgr-related protein ,44% identity(54% similarity) to TrEMBL; Q7P238.TrEMBL;Q8XRU3(44% identity). Signal Peptide Present. Has SMART;SM00438,Repressor of transcription;IPR000967, Znf_NFX1;This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C,where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosophila shuttle craft protein, which plays an essential role during the late stages of embryonic neurogenesis; and a yeast hypothetical protein YNL023C. Has PF04524, Protein of unknown function,DUF586; IPR006533,Rhs_Vgr;This family contains a conserved region in several bacterial proteins of unknown function.; High confidence in function and specificity
YP_934973.1	Conserved hypothetical protein. Homology to RS02436 of R.solanacearum of 41% (trembl:Q8XUG9). No domains predicted. No signal peptide present. No TMH reported present.
YP_934974.1	Conserved hypothetical secreted protein. Homology to RS02435 of R. solanarcearum of 43% (trembl|Q8XUH0(SRS)). No domains predicted. Signal Peptide present. No TMH reported present.; Conserved hypothetical protein
YP_934975.1	Conserved hypothetical protein. Homology to RS02435 of R. solanacearum of 47% (trembl:Q8XUH0). No domains predicted. No signal peptide. No TMHs
YP_934976.1	Conserved hypothetical secreted protein. Homology to RS02435 of R. solanarcearum of 44% (trembl|Q8XUH0(SRS)). No domains predicted. Signal Peptide present. No TMH reported present; Conserved hypothetical protein
YP_934977.1	Putative mcp-domain signal transduction protein,; Conserved hypothetical protein
YP_934978.1	Putative signal-transduction sensor protein,; Conserved hypothetical protein
YP_934980.1	Conserved hypothetical secreted protein. Homology to rsc2369 of R. solanacearum of 52% (trembl|Q8XWV1). no damians predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_934981.1	Putative formate dehydrogenase gamma subunit. Homology to fdhC of W. succinogenes of 21% (TREMBL:P28180). Formate dehydrogenase is a membrane-bound complex, formed of at least three different subunits; probable heterotetramer of two FDHA, one FDHB and one FDHC. FdhC probably anchors the enzyme in the membrane and IS PROBABLY THE CYTOCHROME B556(FDO) COMPONENT. no good domains signal peptide 5 TMHs; Family membership
YP_934982.1	Conserved hypothetical secreted protein. Homology to rsc2371 of R. solanacearum of 36% (trembl|Q8XWU9). no doamins predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_934983.1	probable formate dehydrogenase iron-sulfur subunit. Homology to fdhB of W. succinogenes of 63% (SWISSPROT:FDHB_WOLSU) THIS CHAIN IS AN ELECTRON TRANSFER UNIT CONTAINING 18 CYSTEINE RESIDUES 16 OF WHICH OCCUR IN THREE CLUSTERS. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450); 7Fe ferredoxin (IPR000813); 3Fe-4S ferredoxin (IPR001080) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_934984.1	Probable formate dehydrogenase alpha subunit. Homology to fdha of W. succinogenes of 44% (pir|S18213) The formate dehydrogenase catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain singal peptide no TMHs; High confidence in function and specificity
YP_934985.1	Conserved hypothetical secreted protein. Homology to rsc2374 of R. solanacearum of 39% (trembl|Q8XWU6). no domains predicted. signal peptide. TMH in signal peptide; Conserved hypothetical protein
YP_934986.1	Putative Chaperone protein TorD. Homology to torD of E. coli of 23% (sprot|TORD_ECOLI). This family consists of several bacterial TorD proteins. Many prokaryotic molybdoenzymes, for example the TMAO reductase (TorA) of Escherichia coli, require the insertion of a bis(molybdopterin guanine dinucleotide) molybdenum (bis(MGD)Mo) cofactor in its catalytic site to be active and translocated to the periplasm. The TorD chaperone increases apoTorA activation up to four-fold, allowing maturation of most of the apoprotein. Therefore TorD is involved in the first step of TorA maturation to make it competent to receive the cofactor. Pfam: Cytoplasmic chaperon no signal peptide no TMHs; Family membership
YP_934987.1	Conserved hypothetical iron-sulfur binding protein. Homology to pb1470 of B. pertussis of 48% (trembl|Q7VY84). Transfer of electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs; Family membership
YP_934988.1	Conserved hypothetical protein. Homology to RS01168 of R.solanacearum of 40% (trembl:Q8XWU3). No domains predicted. No signal peptide or TMH reported present.
YP_934989.1	Conserved hypothetical protein. Homology to BPP1929 of B.parapertussis of 34% (trembl:34%). No signal peptide or TMH reported present. No domains predicted.
YP_934990.1	Putative formate dehydrogenase accessory protein. Homology to fdhD of W. succinogenes of 20% (sprot|FDHD_WOLSU). Necessary for formate dehydrogenase activity (By similarity). InterPro: Formate dehydrogenase subunit FdhD (IPR003786). Pfam: FdhD/NarQ family no signal peptide no TMHs; Family membership
YP_934991.1	Probable molybdopterin-guanine dinucleotide biosynthesis protein A, 46% Identity to SwissProt;Q8Y0K5. TrEMBL;Q62LV3(44% Identity)Q63S71 Has PF01128,Uncharacterized protein family UPF0007;IPR001228 ISPD_synthase; The bacterial ispD protein catalyzes the third step of the deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis; the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate.
YP_934992.1	Conserved hypothetical protein. Homology to ebA2947 of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA2947(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_934993.1	Molybdopterin-guanine dinucleotide biosynthesis protein B. MAY BIND THE GUANINE NUCLEOTIDE REQUIRED FOR THE SYNTHESIS OF MOLYBDOPTERIN GUANINE DINUCLEOTIDE. InterPro: ATP/GTP-binding site motif A (P-loop) TIGRFAM: mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity
YP_934994.1	Putative sensor histidine kinase, His_kinA_N. IPR009082; His_kin_homodim. IPR003660; HAMP. IPR003594; ATPbind_ATPase. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. TMHMM reporting 2 transmembrane helices.; Specificity unclear
YP_934995.1	Probable sigma-54 dependent response regulator,AAA_ATPase. IPR008931; FIS-like. IPR002197; HTH_Fis. IPR010114; NtrC. IPR001789; Response_reg. IPR008298; Res_reg_NtrC. IPR002078; Sig54_interact. Pfam: PF02954; HTH_8. PF00072; Response_reg. PF00158; Sigma54_activat. SMART: SM00382; AAA. SM00448; REC. HTH reporting reporting nucleic acid binding motif.; Family membership
YP_934996.1	Conserved hypothetical membrane protein. Homology to CV0155 of Chromobacterium violaceum of 69% (trembl|Q7P1Q8). Has PF03653, Uncharacterised protein family (UPF0093);IPR005265, Cons_hypoth701:It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. No signal peptide. 4 TMHs; Conserved hypothetical protein
YP_934997.1	55%; Specificity unclear
YP_934998.1	catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose
YP_934999.1	conserved hypothetical regulator protein,; Conserved hypothetical protein
YP_935000.1	Putative sensor protein, no significant homology. Best Hit SWISSPROT: sprot|ZRAS_SALTY (10% Salmonella typhimurium, ZraS) InterPro: IPR003594; ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR005467; His_kinase. Pfam: PF02518; HATPase_c. PF00512; HisKA. SMART: SM00387; HATPase_c. SM00388; HisKA. Signal P reporting signal peptide. Sensor protein zraS (EC 2.7.3.-). Member of the two-component regulatory system zraS/zraR. May function as a membrane-associated protein kinase that phosphorylates zraR in response to high concentrations of zinc or lead in the medium (By similarity).
YP_935001.1	Conserved hypothetical signaling protein. Homology to Daro03001340 of Dechloromonas aromatica of 45% (gi|53730727|ref|ZP_00348932.1|(NBCI ENTREZ)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. IPR001633 EAL. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM: TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain.; Conserved hypothetical protein
YP_935002.1	probable cytochrome c-552 precursor. Homology to cyt of N. europaea of 52% (AAB46987). ELECTRON DONOR FOR CYTOCHROME CD1 IN NITRITE AND NITRATE RESPIRATION. InterPro: Cytochrome c class I (IPR003088); cytochrome c,class ID (IPR002324) Pfam: cytochrome c signal peptide no TMHs; High confidence in function and specificity
YP_935003.1	Urease accessory protein ureG. Homology to ureG of K. aerognes of 71% (AAA25154). Probably facilitates nickel incorporation. Pfam: HypB/UreG nucleotide-binding domain Tigrfam: ureG: urease accessory protein UreG no signal peptide no TMHs; High confidence in function and specificity
YP_935004.1	Probable urease accessory protein ureF. Homology to ureF of K. aerogenes of 41% (sprot|UREF_KLEAE). UreF is proposed to modulate the activation process of urease by eliminating the binding of nickel irons to noncarbamylated protein InterPro: UreF (IPR002639) Pfam: ureF probable signal peptide no TMHs; High confidence in function and specificity
YP_935005.1	involved in the assembly of the urease metallocenter; possible nickel donor
YP_935006.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits
YP_935007.1	Region start changed from 3848352 to 3848310 (-42 bases)
YP_935008.1	Conserved hypothetical protein. Homology to Daro03003730 of Dechloromonas aromatica of 40% (gi|46140350|ref|ZP_00203571.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; Family membership
YP_935009.1	UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter
YP_935010.1	Putative urease accessory protein ureD. PROBABLY FACILITATES NICKEL INCORPORATION. SEEMS TO BE ESSENTIAL FOR UREOLYSIS. InterPro: UreD urease accessory protein Pfam: UreeD urease accessory protein no signal peptide no TMHs; High confidence in function and specificity
YP_935011.1	catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis
YP_935012.1	InterPro: Sulfatase Membrane protein; Specificity unclear
YP_935013.1	Conserved hypothetical secreted protein. Homology to PA0234 of P.aeruginosa of 43% (trembl:Q9I6Q4). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein
YP_935014.1	Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import.Similar to the putative periplasmic-binding protein ssuA precursor in E.coli. SSUA_BACSU:P40400. InterPro:IPR000437; Prok_lipoprot_S. IPR001638; SBP_bac_3. SMART: SM00062; PBPb; 1. TMhelix:1. Signal peptide: present.; Specificity unclear
YP_935015.1	Region start changed from 3855391 to 3855571 (-180 bases)
YP_935016.1	Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import. Probably responsible for the translocation of the substrate across the membrane.26% Similar to the aliphatic sulfonates permease, ssuC in E.coli. SWISSPROT:SSUC_ECOLI: P75851 InterPro:IPR000515; BPD_transp. Pfam:PF00528; BPD_transp; 1. InterPro:PF00528: Binding-protein-dependent transport systems inner membrane component. TMhelix:6; Specificity unclear
YP_935017.1	Putative transcriptional regulatory protein,; Conserved hypothetical protein
YP_935018.1	Flavoprotein wrbA3. TREMBL:Q8PGA8: 53% identity,66% similarity. wrbA3 is 26% identical to wrbA1 and 23% identical to wrbA2 InterPro: IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam:PF00258: flavodoxin; TIGR00301: NADP oxidoreductase coenzyme Number of transmembrane helices:0; High confidence in function and specificity
YP_935019.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
YP_935020.1	CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YP_935021.1	Cobalamin biosynthesis protein, CobC. CobC is probable involved in the conversion of cobyric acid to cobinamide.Similar to pir|B83486 (48%) and to sprot|COBC_PSEDE (42%). InterPro (PF00155): Aminotransferases class-I and II; Specificity unclear
YP_935022.1	Vitamin B12 transport protein btuF precursor. 34% Similar to BtuF from E.coli. Part of the binding-protein-dependent transport system for vitamin B12. Acts with btuCD to transport vitamin B12 across the inner membrane. SWISSPROT:BTUF_ECOLI:P37028 InterPro:IPR002491; Peripla_BP. Pfam: PF01497; Peripla_BP_2; 1. Signal peptide: present. Contains 1 iron siderophore/cobalamin periplasmic- binding domain.; High confidence in function and specificity
YP_935023.1	Conserved hypothetical peptidase. Homology to ebA3686 of Azoarcus sp. EbN1 of 45% (gnl|keqq|eba:ebA3686(KEGG)) . Pfam: Peptidase family M48. signal peptide. 1 TMHs; Conserved hypothetical protein
YP_935024.1	ATP-dependent RNA helicase rhlB (EC 3.6.1.-). Can carry out ATP-dependent unwinding of double stranded RNA. Has a role in RNA decay. Involved in the RNA degradosome a multi-enzyme complex important in RNA processing and messenger RNA degradation.; High confidence in function and specificity
YP_935025.1	Alpha-isopropylmalate synthase catalyses the first step in the biosynthesis of leucine, the condensation of acetyl-CoA and alpha- ketoisovalerate to form 2-isopropylmalate synthase. Similar to sprot|LEU1_PSEAE (59%) and to sprot|LE12_RALSO (68%). Pfam (PF00682): HMG-CoA Lyase-like family; High confidence in function and specificity
YP_935026.1	Conserved hypothetical nitroreductase. Homology to cv1555 of C. violaceum of 72% (trembl|Q7NXS1). Involved in the reduction of nitrogen containing compounds. InterPro: Nitroreductase family (IPR000415). Pfam: Nitroreductase family. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935027.1	TREMBL:Q7NZN8 (43% identity, 53% similarity).
YP_935028.1	Conserved hypothetical flavoprotein. Homology to tde2498 of T. denticola of 46% (tremblnew|AAS13015). InterPro: Metallo-beta-lactamase superfamily (IPR001279). Pfam: Metallo-beta-lactamase superfamily. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935029.1	GGDEF/EAL-domain containing protein
YP_935030.1	Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide.; Conserved hypothetical protein
YP_935031.1	Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. SUMT is the first enzyme specific to the cobalamin pathway and precorrin-2 is a common intermediate in the biosynthesis of corrinoids such as vitamin B12, siroheme and coenzyme F430. The sequences of SUMT from a variety of bacterial and archaeal species are currently available. In species such as Bacillus megaterium (gene cobA),Pseudomonas denitrificans (cobA) or Methanobacterium ivanovii (gene corA) SUMT is a protein of about 25 to 30 kD. In Escherichia coli and related bacteria, the cysG protein, which is involved in the biosynthesis of siroheme, is a multifunctional protein composed of a N-terminal domain, probably involved in transforming precorrin-2 into siroheme, and a C-terminal domain which has SUMT activity.
YP_935032.1	CbiX conserved hypothetical protein. Function unknown. Cobalamin biosynthesis pathway.; Function unclear
YP_935033.1	Precorrin-8X methylmutase . CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity
YP_935034.1	Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A
YP_935035.1	Precorrin-6 methyltransferase (Precorrin-6Y methylase). CATALYZES THE METHYLATION OF BOTH C-5 AND C-15 IN PRECORRIN-6Y TO FORM PRECORRIN-8X. InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity
YP_935036.1	Precorrin-2 C20-methyltransferase (EC 2.1.1.130) (S-adenosyl-L- methionine:precorrin-2 methyltransferase) (SP2MT). METHYLATES PRECORRIN-2 AT THE C-20 POSITION TO PRODUCE PRECORRIN-3A.; High confidence in function and specificity
YP_935037.1	putative Cobalamin (vitamin B12) biosynthesis CbiG protein, truncated. Homology to the N-terminus of cbiG of b. magaterium of 39% (gi|3724046|emb|CAA04315.1|(nr)). Pfam: CibG, CbiG proteins are required for cobalamin (vitamin B 12 ) biosynthesis. IPR012407: Cobalamin (vitamin B12) biosynthesis CbiG. CbiG is one of the enzymes specific to the anaerobic route of cobalamin biosynthesis e.g., in Salmonella typhimurium. While its specific role in this pathway is not known yet, it has been speculated that CbiG may participate in the conversion of cobalt-precorrin 5 into cobalt-precorrin 6. This step requires opening of the delta-lactone ring,excision of acetaldehyde and C-1 methylation. Alternatively, it has been suggested that it may participate in ring contraction. no signal peptide. no TMHs; Function unclear
YP_935038.1	C-terminal part of CbiG protein. Cobalamin biosynthesis pathway.Precorrin methylase; High confidence in function and specificity
YP_935039.1	Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity
YP_935040.1	Conserved hypothetical ferredoxin. Homology to rsp0627 of R. solanacearum of 46% (trembl|Q8XS54). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935041.1	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs
YP_935042.1	Conserved hypothetical transcriptional regulatory protein. Homology to rsc0599 of R. solanacearum of 63% (trembl|Q8Y1U0). InterPro: Bacterial regulatory proteins GntR family (IPR000524). Pfam: Bacterial regulatory protein, gntR family; Aminotransferase classI and II. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935043.1	Hypothetical methyltransferase. no Homology of the entire protein with the data bank. Pfam: Putative methyltransferase This is a family of hypothetical proteins which are putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity. Interpro: SAM (and some other nucleotide) binding motif(IPR000051) no signal peptide no TMHs
YP_935044.1	Conserved hypothetical glutathione transferase. Homology to psto0703 of P. syringae of 74% (trembl|Q889P6). Bacterial GSTs of known function often have a specific, growth-supporting role in biodegradative metabolism Pfam. Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal. no signal peptide. no TMHs; Family membership
YP_935045.1	Hypothetical secreted protein. No homology of the entire protein to the data bank. Pfam: DUF1555 (domain of unknown function). signal peptide. no TMHs
YP_935046.1	probable 4-hydroxybutyrate coenzyme A transferase. Homology to cat2 of C. kluyveri of 43% (sprot|CAT2_CLOKL) InterPro: Acetyl-CoA hydrolase/transferase (IPR003702) Pfam: Acetyl-CoA hydrolase/transferase no signal peptide no TMHS; Family membership
YP_935047.1	Conserved hypothetical transport membrane protein. Homology to rsc1520 of R. solanacearum of 59% (trembl|Q8XZ84). Pfam: LysE type translocator. Tigrfam: 2A76: Homoserine/Threonine efflux protein. no signal peptide. probable 6 TMHs; Family membership
YP_935048.1	Probable carboxypeptidase TAQ. Homology to ctaQ of T. aquaticus of 40% (SWISSPROT:CTAQ_THEAQ) Releases amino acids sequentially from the C-terminus with a broad substrate specificity (except for proline). Pfam: carboxypeptidas Taq (M32) metallopep no signal peptide no TMHs; Family membership
YP_935049.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. signal peptide present.
YP_935050.1	Conserved hypothetical secreted protein. Homology to cv0063 of C. violaceum of 41% (trembl|Q7P1Z9(SRS)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_935051.1	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine
YP_935052.1	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
YP_935053.1	Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity
YP_935054.1	catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide
YP_935055.1	37% Similar to the iron(III)-hydroxamate transport membrane protein, fhuC in E.coli.Part of the ABC transporter complex fhuACDB involved in iron(III)-hydroxamate import. Probably responsible for energy coupling to the transport system. SWISSPROT:FHUC_ECOLI:P07821 InterPro:IPR003593; AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1.; High confidence in function and specificity
YP_935056.1	Region start changed from 3899167 to 3899122 (-45 bases)
YP_935057.1	COBALAMIN RECEPTOR PROTEIN.; Specificity unclear
YP_935058.1	Putative outer membrane TonB-dependent receptor,probably involved in iron metabolism. 20% Similar to the IrgA enterobactine outer membrane receptor in V. cholerae. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC VIBRIOBACTIN AN IRON CHELATIN SIDEROPHORE THAT ALLOWS V.CHOLERAE TO EXTRACT IRON FROM THE ENVIRONMENT. SWISSPROT:IRGA_VIBCH:P27772. 21% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1.; Specificity unclear
YP_935059.1	Bifunctional cobalamin biosynthesis protein cobU [Includes: Cobinamide kinase; Cobinamide phosphate guanylyltransferase]. ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate. InterPro: Cobalbumin biosynthesis enzyme; High confidence in function and specificity
YP_935060.1	Conserved hypothetical membrane protein. Homology to gsu0462 of G. sulfurreducens of 41% (AAR33794). probable 2 TMHs. no signal peptide. No domains predicted.; Conserved hypothetical protein
YP_935061.1	Hypothetical membrane protein. No homology of the whole protein to the data bank. Has PF05987, Bacterial protein of unknown function (DUF898);IPR010295 ; This family consists of several bacterial proteins of unknown function. Some of the family members are described as putative membrane proteins. No signal peptide 6 TMHs
YP_935062.1	catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole
YP_935063.1	catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole
YP_935064.1	Alpha-ribazole-5-phosphate phosphatase. Converts N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6-dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin. 27% PG/BPGM_mutase. Pfam:PF00300; PGAM; 1.; High confidence in function and specificity
YP_935065.1	ADP-heptose synthase (EC 2.7.-.-).; High confidence in function and specificity
YP_935066.1	59% Epimerase_Dh.IPR000205; NAD_BS. Pfam:PF01370; Epimerase; 1. Non-secretory protein.; High confidence in function and specificity
YP_935067.1	ADP-heptose--LPS heptosyltransferase II (EC 2.-.-.-).; High confidence in function and specificity
YP_935068.1	Lipopolysaccharide heptosyltransferase-1 (EC 2.-.-.-). HEPTOSE TRANSFER TO THE LIPOPOLYSACCHARIDE CORE. IT TRANSFERS THE INNNERMOST HEPTOSE TO [4-P](3-DEOXY-D-MANNO-OCTULOSONIC ACID)2-IVA. S18: ribosomal protein S18; High confidence in function and specificity
YP_935069.1	Region start changed from 3913496 to 3913541 (-45 bases)
YP_935070.1	Lipopolysaccharide core biosynthesis protein rfaP. Specific function unclear. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE.
YP_935071.1	Lipopolysaccharide core biosynthesis protein rfaP. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear.
YP_935072.1	Lipopolysaccharide core biosynthesis protein. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear.
YP_935073.1	InterPro: Eukaryotic protein kinase. Might be related to lipopolysaccharide biosynthesis, due to the presence of the gene in a lipopolysaccharide gene cluster.
YP_935074.1	Lipid A export ATP-binding protein msbA. MsbA (TC 3.A.1.106.1) is involved in lipid A and possibly also glycerophospholipids export. The transmembrane domain (TMD) forms a pore in the inner membrane and the ATP-binding domain (NBD) is responible for energy generation. Similar to TREMBL:Q9HUG8; TREMBL:Q88D92; SWISSPROT:P60752 (39% identity). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting five transmembrane helices. TC (3.A.1.106): The Lipid Exporter (LipidE) Family.; High confidence in function and specificity
YP_935075.1	Conserved hypothetical protein, 43% identity(65% similarity) to TrEMBL|Q9HUG7,Hypothetical protein PA4998 [PA4998] [Pseudomonas aeruginosa]. Has PF06293:IPR010440:Lipopolysaccharide kinase (Kdo/WaaP) family;These lipopolysaccharide kinases are related to protein kinases Pkinase. This family includes waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region. It has previously been shown that WaaP is necessary for resistance to hydrophobic and polycationic antimicrobials in E. coli and that it is required for virulence in invasive strains of S. enterica. No Signal Peptide or TMH reported present.
YP_935076.1	Hypothetical membrane protein. Homology to pspto4986 of P. syringae of 28% (trembl|Q87VF1(SRS)) No domains predicted signal peptide 9 TMHs
YP_935077.1	Family membership
YP_935079.1	Possibly related to cell surface polysaccharide biosynthesis, due to the presence of the gene in a polysaccharide synthesis gene cluster.
YP_935080.1	Specificity unclear
YP_935081.1	Putative carbamoyltransferase. Homology to nolU of Rhizobium sp. NGR234 of 33% InterPro: Carbamoyltransferase Pfam: Carbamoyltransferase no signal peptide no TMHs; Family membership
YP_935082.1	Catalysis of the reactions of the type: acyl-carrier + reactant = acyl-reactant + carrier. Entry name : Q888M0 InterPro : IPR002656; Acyl_transf_3. Identity: 227/677 (33%) Pfam PF01757; Acyl_transf_3; 1. Prediction: Non-secretory protein Signal peptide probability: 0.005(almost Yes) Number of predicted TMHs: 10; Family membership
YP_935083.1	48% Polysac_CapD. Pfam:PF02719; Polysacc_synt_2; 1.; High confidence in function and specificity
YP_935084.1	Similar to proteins annotated as phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP- MurNAc-pentapeptide phosphotransferase). First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity).; Function unclear
YP_935085.1	50%; High confidence in function and specificity
YP_935086.1	InterPro: Glycosyl transferases group 1; Specificity unclear
YP_935087.1	Putative glycosyl transferase MJ1057 (EC 2.-.-.-). InterPro: Glycosyl transferase family 2; Family membership
YP_935088.1	GDP-L-fucose synthetase (GDP-4-keto-6-deoxy-D-mannose-35-epimerase -4-reductase). Two step NADP-dependent conversion of GDP-4-dehydro-6- deoxy-D-mannose to GDP-fucose involving an epimerase and a reductase reaction.54% ADH_short.IPR001509; Epimerase_Dh. Pfam:PF01370; Epimerase. Non-secretory protein.; High confidence in function and specificity
YP_935089.1	[EC:4.2.1.47] , GDP-mannose 4,6-dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase)., GDP-mannose 4,6-dehydratase, NAD dependent epimerase/dehydratase family,gmd: GDP-mannose 4,6-dehydratase; High confidence in function and specificity
YP_935090.1	Hypothetical membrane protein. No homology to the data bank. No domains predicted. no signal peptide. 9 TMHs; Conserved hypothetical protein
YP_935091.1	InterPro: Glycosyl transferase family 2. Slight similarity to dolicholphosphate mannosyltransferases,might therefore transfer a sugar moiety directly to a lipid carrier.; Specificity unclear
YP_935092.1	Low similarity with the EmrE protein (Methyl viologen resistance protein C)(Ethidium resistance protein)in E.coli. Multidrug transporter. Confers resistance to a wide range of toxic compounds by removing them for the cells. The efflux is coupled to an influx of protons. Probably prevents the incorporation of methyl viologen into cells. Involved in ethidium bromide efflux. EMRE_ECOLI:P23895. InterPro:IPR000390; Smr. Pfam: PF00893; Multi_Drug_Res; 1. Signal peptide present. TMHelix: 4.; High confidence in function and specificity
YP_935093.1	Family membership
YP_935094.1	Gene located in a gene cluster related to an unidentified cell surface polysaccharide
YP_935095.1	Hypothetical membrane protein. No good homology of the entire protein with the data bank. No domains predicted. No signal peptide. 1 TMH
YP_935096.1	Putative glycosyl transferase sll0501 (EC 2.-.-.-).; Specificity unclear
YP_935098.1	44% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom:PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 1.
YP_935099.1	51% ABC_transpt2. Pfam:PF01061; ABC2_membrane; 1. TMhelix:6. Non-secretory protein.; Specificity unclear
YP_935100.1	Possibly related to cell surface biosynthesis, ue to the location of he gene in a polysaccharide synthesis gene cluster.
YP_935101.1	49%; High confidence in function and specificity
YP_935102.1	DNA polymerase I (EC 2.7.7.7) (POL I). IN ADDITION TO POLYMERASE ACTIVITY THIS DNA POLYMERASE EXHIBITS 3 TO 5 AND 5 TO 3 EXONUCLEASE ACTIVITY. IT IS ABLE TO UTILIZE NICKED CIRCULAR DUPLEX DNA AS A TEMPLATE AND CAN UNWIND THE PARENTAL DNA STRAND FROM ITS TEMPLATE. InterPro: Replicative DNA polymerase; High confidence in function and specificity
YP_935103.1	Hypothetical protein PA4923. TREMBL:Q82UL5: 68% identity, 82% similarity InterPro:IPR005269; Cons_hypoth730. Pfam:PF03641; Lysine_decarbox; 1. TIGRFAMs:TIGR00730; Cons_hypoth730 bcl-2: Apoptosis regulator Non-secretory protein with signal peptide probability 0(Signal P predicted9 Absence of transmembrane helices (TMHHH predicted); Function unclear
YP_935104.1	Conserved hypothetical secreted protein. Homology to CV0777 of C.violaceum of 42% (trembl|Q7NZZ2(SRS)). No domains predicted. Signal peptide present. No TMH reported.; Conserved hypothetical protein
YP_935106.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine
YP_935107.1	Conserved hypothetical membrane protein. Homology to cv0192 of C. violaceum of 32% (trembl|Q7P1M1(SRS)). No domains predicted. No signal peptide. 6 TMHs.; Conserved hypothetical protein
YP_935108.1	Conserved hypothetical protein. Homology to ne1472 of N. europaea of 33% (trembl|Q82UL2(SRS)). No domains predicted. No signal peptide. 6 TMHs.
YP_935109.1	Probable nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase) (Deamido-NAD(+) diphosphorylase) (Nicotinate mononucleotide adenylyltransferase) (NaMN adenylyltransferase). Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity). InterPro: Cytidylyltransferase; High confidence in function and specificity
YP_935110.1	Conserved hypothetical protein. Homology to NE0358 of Nitrosomonas europaea of 55% (trembl:Q82XC6). Pfam:Domain of unknown function DUF143. This domain has no known function nor do any of the proteins that possess it. The aligned region is approximately 100 amino acids long. Tigrfam: TIGR00090 iojap-related protein. This model describes a strictly bacterial family of proteins related to iojap from plants. The gene iojap is a pattern-striping gene in maize, reflecting a chloroplast development defect in some cells. Maize has two RNA polymerases in plastids,but the plastid-encoded one
YP_935111.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_935112.1	Probable peptide deformylase (EC 3.5.1.88). Homology to def of E. coli of 42% (sprot|DEF_ECOLI(SRS)). Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions Interpro: Formylmethionine deformylase (IPR000181) Pfam: Polypeptide deformylase Tigrfam: pept_deformyl: polypeptide deformylase no signal peptide no TMHs; High confidence in function and specificity
YP_935113.1	Homology to Maf-like proteins; Family membership
YP_935114.1	Ribonuclease G (EC 3.1.4.-) (RNase G) (Cytoplasmic axial filament protein). INVOLVED IN PROCESSING OF THE 5END OF 16S RRNA. COULD BE INVOLVED IN CHROMOSOME SEGREGATION AND CELL DIVISION. IT MAY BE ONE OF THE COMPONENTS OF THE CYTOPLASMIC AXIAL FILAMENTS BUNDLES OR MERELY REGULATE THE FORMATION OF THIS STRUCTURE.; Family membership
YP_935115.1	Probable 14-dihydroxy-2-naphthoate octaprenyltransferase (EC 2.5.1.-) (DHNA-octaprenyltransferase). CONVERSION OF 1,4-DIHYDROXY-2-NAPHTHOATE (DHNA) TO DIMETHYLMENAQUINONE (DMK). ATTACHES OCTAPRENYLPYROPHOSPHATE A MEMBRANE-BOUND 40-CARBON SIDE CHAIN TO DHNA. THE CONVERSION OF DHNA TO DMK PROCEEDS IN THREE STAGES: THE REMOVAL OF THE CARBOXYL GROUP OF DHNA AS CO2 THE ATTACHMENT OF THE ISOPRENOID SIDE CHAIN AND A QUINOL-TO-QUINONE OXIDATION WHICH IS THOUGHT TO BE SPONTANEOUS (BY SIMILARITY). TIGRFAM: menA: 14-dihydroxy-2-naphthoate octaprenyltransferase; Specificity unclear
YP_935116.1	Conserved hypothetical membrane protein. Homology to PA0359 of Pseudomonas aeruginosa of 35% (trembl|Q9I6D5(SRS)). No domains predicted. signal peptide. 1 TMHs; Conserved hypothetical protein
YP_935117.1	Transcriptional regulatory protein, Trans_reg_C. IPR001789 Response_reg. Pfam: PF00486; trans_reg_C. PF00072 response_reg. SMART: SM00448 REC.; Specificity unclear
YP_935118.1	Putative sensor histidine kinase, ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR009082; His_kin_homodim. IPR003660; HAMP. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. TMHMM reporting 2 transmembrane helices.; Specificity unclear
YP_935119.1	Putative calcium binding protein,40% similarity to TrEMBL;O22845. Has 3 EFh|EF-hand, calcium binding motif;(SMART|SM00054):Many calcium-binding proteins belong to the same evolutionary family and share a type of calcium-binding domain known as the EF-hand. This type of domain consists of a twelve residue loop flanked on both side by a twelve residue alpha-helical domain. In an EF-hand loop the calcium ion is coordinated in a pentagonal bipyramidal configuration. The six residues involved in the binding are in positions 1, 3, 5, 7, 9 and 12; these residues are denoted by X, Y, Z, -Y, -X and -Z. The invariant Glu or Asp at position 12 provides two oxygens for liganding Ca (bidentate ligand). NO Signal peptide or TMh reported present.; Family membership
YP_935120.1	Glycine cleavage system transcriptional activator (Gcv operon activator). Regulatory protein for the glycine cleavage system operon (gcv). Mediates activation og gcv by glycine and repression by purines. GcvA is negatively autoregulated. Bind to three sites upstream of the gcv promoter. Similar to SWISSPROT: sprot|GCVA_ECOLI (39% Escherichia coli, glycine cleavage system transcriptional activator (gcv operon activator)) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_935121.1	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs
YP_935122.1	Putative adenylate/ guanylate cyclase,; Function unclear
YP_935123.1	DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I) . HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity
YP_935124.1	Probable transcriptional regulator, LysR family,; Family membership
YP_935125.1	Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity
YP_935126.1	TREMBL:Q88ME4: 72% identity,83% similarity Esterase D (EC 3.1.1.1). This family contains several seemingly unrelated proteins, including human esterase D; mycobacterial antigen 85, which is responsible for the high affinity of mycobacteria to fibronectin; Corynebacterium glutamicum major secreted protein PS1; and hypothetical proteins from Escherichia coli, yeast,mycobacteria and Haemophilus influenzae. InterPro:IPR000801; Esterase_put. IPR000379; Ser_estrs. Pfam: PF00756; Esterase; InterPro: Putative esterase Absence of signal peptide and transmembrane helices; Specificity unclear
YP_935127.1	Hypothetical membrane protein. no homology to the data bank no doamains predicted no signal peptide 1 TMH
YP_935128.1	Conserved hypothetical chaperon protein: Homology to cv2395 of C. violaceum of 62% (trembl|Q7NVE8). InterPro: Heat shock protein hsp70 (IPR001023). Pfam: Hsp70 protein. no signal peptide. no TMHs; Family membership
YP_935129.1	Conserved hypothetical SLT domain protein. Homology to NE2226 of N.europaea of 42% (trembl|Q82SS9(SRS). Pfam: Transglycosylase SLT domain. Bacterial lytic transglycosylases degrade murein via cleavage of the beta-1,4- glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, with the concomitant formation of a 1,6-anhydrobond in the muramic acid residue. Escherichia coli has at least three different lytic transglycosylases: two soluble isozymes of 65 Kd and 35 Kd and a membrane-bound enzyme of 38 Kd. The sequence of the 65 Kd enzyme (gene slt) has been determined. A domain of about 90 residues located near the C-terminal section of slt was recently shown to be present in a number of other prokaryotic and phage proteins. This SLT domain shared by these proteins is involved in catalytic activity. The most conserved part of this domain contains the contains two conserved serines and a glutamate which form part of this active site signature. no TMHs. signal peptide; Conserved hypothetical protein
YP_935130.1	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank no domains predicted no signal peptide no TMHs
YP_935131.1	Transcriptional regulator, LysR family,; High confidence in function and specificity
YP_935132.1	Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12.; Specificity unclear
YP_935133.1	25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin synthase beta subunit No signal peptide (non secretory protein) predicted by Signal P and no transmembrane helices (predicted by TMHMM).; High confidence in function and specificity
YP_935134.1	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR001140): ABC transportertransmembrane region. Pfam (PF00664): ABC transporter transmembrane region. Pfam (PF00005): ABC transporter. TMHMM reporting six transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; High confidence in function and specificity
YP_935135.1	Hypothetical secreted protein. No significant homology over the entier protein. signal peptide no TMHs
YP_935136.1	Probable D-(-)-3-hydroxybutyrate oligomer hydrolase. Homology to a orf of Ralstonia pickettii of 48% (gi|2154711|dbj|BAA20331.1|(NCBI ENTREZ)). Catalysis of the reaction: (R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O = 2 (R)-3-hydroxybutanoate. No doamis predicted. Signal peptide. TMHs in signal peptide.,; Family membership
YP_935137.1	Conserved hypothetical acetyltransferase. Homology to cv2337 of C. violaceum of 43% (AAQ60009). InterPro: GCN5-related N-acetyltransferase (IPR000182). Pfam: Acetyltransferase (GNAT) family. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935138.1	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (Hexosephosphate aminotransferase) (D-fructose-6- phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase). Catalyzes the first step in hexosamine metabolism converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity). InterPro: Glutamine amidotransferase class-II TIGR00274: glucokinase regulator-rela; High confidence in function and specificity
YP_935139.1	Bifunctional glmU protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.57)]. Bifunctional enzyme responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and the synthesis of UDP-GlcNAc. InterPro: ADP-glucose pyrophosphorylase ispD: 4-diphosphocytidyl-2C-methyl-D-e; High confidence in function and specificity
YP_935140.1	Conserved hypothetical phosphate acetyltransferase. Homology to pta of R. palustris of 63% (tremblnew|CAE30007). InterPro: Phosphate acetyl/butaryl transferase (IPR002505); MaoC-like dehydrogenase domain (IPR002539). Pfam: MaoC like domain; Phosphate acetyl/butaryl transferase. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935141.1	probable acetate kinase. Homology to ackA of s. meliloti of 46% (sprot|ACK2_RHIME) Acetate kinase is involved in the activation of acetate to acetyl CoA and in the secretion of acetate. It catalyzes the reaction ATP + acetate = ADP + acetyl phosphate. InterPro: Acetate kinase (IPR004372); acetate and butyrate kinase (IPR000890) Pfam: Acetokinase family Tigrfam: ackA: acetate kinase no singal peptide no TMHs; High confidence in function and specificity
YP_935142.1	Conserved hypothetical membrane protein. TREMBL:Q9A2S0: 40% identity InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81. Non secretory protein (signal peptide probablity:0.035) and presence of 7 transmembrane helices (TMHMM predicted).; Conserved hypothetical protein
YP_935143.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
YP_935144.1	Ferredoxin-dependent glutamate synthase,; Specificity unclear
YP_935145.1	dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate
YP_935146.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_935147.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_935148.1	Type 4 fimbrial biogenesis protein PilQ, similarity to sprot|PILQ_PSEAE (41%) and trembl|Q8XV60 (45%). PilQ is essential for the biogenesis of type IV pili. Its precise function is unknown, but it has been suggested that it may act as a pilus channel in the final stages of pilus assembly. InterPro (PF00263): General (type II) secretion pathway (GSP) D protein SignalP reporting signal peptide.; Specificity unclear
YP_935149.1	Type 4 fimbrial biogenesis protein, PilP. PilP is essential for the biogenesis of type IV pili. Similar to trembl|Q7NZU1(37%). SignalP reporting Signal Peptide.; Family membership
YP_935150.1	Type 4 fimbrial biogenesis protein PilO, similarity to pir|S77728 (40%). PilO proteins are involved in the assembly of pilin. TMHMM reporting one TMH.; Specificity unclear
YP_935151.1	Type 4 fimbrial biogenesis protein PilN, similarity to trembl|Q82SK2(51%)and to pir|S77727(42%). In P. aeruginosa PilN was found to be required for fimbrial biogenesis by complementation studies using twitching motility and sensitivity to fimbrial-specific phage as indicators of the presence of functional fimbriae. SignalP reporting signal peptide.; Specificity unclear
YP_935152.1	Type 4 fimbrial biogenesis protein PilM, similarity to trembl|Q82SK1 (56%)and to pir|S77726 (47%). Four genes,pilM-P, encode the necessary proteins and pilM is required for the assembly of the type IV fimbriae in Pseudomonas aeruginosa.; Specificity unclear
YP_935153.1	Probable penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin- insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]. Homology to mrcA of N. meningitides of 47% (sprot|PBPA_NEIMA(SRS)) Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity). InterPro: Penicillin binding protein transpeptidase domain (IPR001460); Glycosyltransferase family 51 (IPR001264) Pfam: Transglycosylase; Penicillin binding protein transpeptidase singal peptide no TMHs HTH predicted; High confidence in function and specificity
YP_935154.1	CyaY protein that belongs to the frataxin family.Probably involved in iron metabolism. 33% similarity to CyaY protein from E.coli. SWISSPROT:CYAY_YERPE:P46356 InterPro:IPR002908; Frataxin_like. Pfam:PF01491; Frataxin_Cyay; 1.; High confidence in function and specificity
YP_935155.1	Conserved hypothetical secreted protein. Homology to ypo3846 of Y. pestis of 42% (trembl|Q8ZAF7). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_935156.1	Diaminopimelate decarboxylase, LysA. Similar to sprot|DCDA_PSEAE (64%). Pyridoxal-dependent decarboxylases that act on ornithine-, lysine-, arginine- and related substrates can be classified into different families on the basis of sequence similarity. Prokaryotic diaminopimelic acid decarboxylase (DAPDC) catalyses the conversion of diaminopimelic acid into lysine, the final step of lysine biosynthesis. InterPro(PR01181): Diaminopimelate decarboxylase InterPro(PF00278): Orn/DAP/Arg decarboxylases family 2; High confidence in function and specificity
YP_935157.1	Conserved hypothetical protein. Homology to ebA2272 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA2272(KEGG)). No domains predicted. No TMHs. No signal peptide.
YP_935158.1	Penicillin-binding protein 4 precursor (PBP-4) [Includes: D-alanyl-D- alanine carboxypeptidase (EC 3.4.16.4) (DD-peptidase) (DD- carboxypeptidase); D-alanyl-D-alanine-endopeptidase (DD-endopeptidase)]. Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction. PBP4: D-alanyl-D-alanine carboxypeptid; High confidence in function and specificity
YP_935159.1	Conserved hypothetical membrane protein. Homology to bb4211 of B. bronchiseptica of 37% (trembl|Q7WFQ9(SRS)). No domains predicted. No signal peptide. 3 TMHs; Conserved hypothetical protein
YP_935160.1	3-octaprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) (Polyprenyl p-hydroxybenzoate decarboxylase). CATALYZES THE DECARBOXYLATION OF 3-OCTAPRENYL-4-HYDROXY BENZOATE TO 2-OCTAPRENYLPHENOL (BY SIMILARITY).; High confidence in function and specificity
YP_935161.1	type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_935162.1	Modulates the activities of several enzymes which are inactive in their acetylated form
YP_935163.1	Conserved hypothetical molybdopterin oxidoreductase. Homology to rsc2859 of R. solanacearum of 60% (trembl|Q8XVH2). Tigrfam: bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxidoreductases. Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain. Helixturnhelix motif. no signal sequenz. no TMHs; Conserved hypothetical protein
YP_935164.1	Conserved hypothetical secreted proteinn. Homology to ebA3326 Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA3326(KEGG)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_935165.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_935166.1	Exodeoxyribonuclease (EC 3.1.11.2). InterPro: AP endonucleases family 1; High confidence in function and specificity
YP_935167.1	Conserved hypothetical signaling protein. Homology to IL2267 of Idiomarina loihiensis of 35% (gnl|keqq|ilo:IL2267(KEGG)). InterPro: IPR001633 EAL. IPR000160 GGDEF. Pfam: PF00563 EAL. PF00990 GGDEF. SMART: SM00267 DUF1. SM00052 DUF2. TIGRFAM:TIGR00254 GGDEF. Signaling protein ykoW. Probable signaling protein whose physiological role is not yet known. no signal peptide. No TMHs; Conserved hypothetical protein
YP_935168.1	Putative sensor histidine kinase, low similarity to SWISSPROT: sprot|KINB_PSEAE (13% Pseudomonas aeruginosa,alginate biosynthesis sensor protein KinB) / TREMBL: trembl|Q50853 (13% Myxococcus xanthus, AsgA) InterPro: IPR004358 Bact_sens_pr_C. IPR003661 His_kinA_N. IPR005467 His_kinase. Pfam: PF02518 HATPase_c. PF00512 HisKA. SMART: SM00387 HATPase_c. SM00388 HisKA. TMHMM reporting 1 transmembrane helices.; Family membership
YP_935169.1	Conserved hypothetical membrane protein. Homology to RS05100 of Ralstonia solanacearum of 50% (trembl|Q8Y1D7(SRS)). Has PF05957, Bacterial protein of unknown function (DUF883);IPR010279; This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide. 1 TMH; Conserved hypothetical protein
YP_935170.1	Conserved hypothetical membrane protein. Homology to rs05101 R. solanacearum of 36% (trembl|Q8Y1D8(SRS)). No domains predicted. No signal peptide. 2 TMHs; Conserved hypothetical protein
YP_935171.1	Conserved hypothetical protein. Homology to ebD74 of Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebD74(KEGG)). No domains predicted. No signal peptide. No TMHs.
YP_935172.1	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively
YP_935173.1	Conserved hypothetical protein. Homology to BPP4351 of B.parapertussis of 38% (trembl:Q7W2Q3). No domains predicted. No TMHs. No signal peptide.
YP_935174.1	DNA-binding response regulator,; High confidence in function and specificity
YP_935175.1	Two-component system histidine kinase,; High confidence in function and specificity
YP_935176.1	Probable serine protease MucD. Homology to mucD of P. aeruginosa of 51% (trembl|Q57155) Pfam: Trypsin; PDZ domain (Aslo konwn as DHR or GLGF) no TMH signal peptide; High confidence in function and specificity
YP_935177.1	Hypothetical protein predicted by Glimmer/Critica. Homology to bpp3105 of B. parapertussis of 20% (trembl|Q7W622). no domains predicted. no signal peptide. no TMHs
YP_935178.1	Probable maleylpyruvate isomerase. Homology to nagL of Ralstonia spU of 50% (trembl|O86043) NagL is a reduced glutathione-dependent maleylpyruvate isomerase catalyzing the isomerization of maleypyruvate to fumarylpyruvate. InterPro: Glutathione S-transferase N terminus (IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminal domaine no signal peptide no TMHs; High confidence in function and specificity
YP_935179.1	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 23% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present.; Specificity unclear
YP_935180.1	This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. Similar to TREMBL:Q9KSB3 (67% identity); TREMBL:Q92LT4 (67% identity); TREMBL:Q8EGD4 (61% identity). Pfam (PF01557): Fumarylacetoacetate (FAA) hydrolase family.; Family membership
YP_935181.1	Glyoxalase I (lactoylglutathione lyase) catalyzes the first step of the glyoxal pathway. Similar to trembl|Q89SS0 (63%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Family membership
YP_935182.1	Conserved hypothetical protein. Homology to RS01748 of R.solanacearum of 59% (trembl:Q8XRY0). No domains predicted. No TMHs. No signal peptide.
YP_935183.1	Putative oxygenase. 3-(3-hydroxy-phenyl)propionate hydroxylase (EC 1.14.13.-), InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); Specificity unclear
YP_935184.1	Beta-lactamase II precursor (EC 3.5.2.6) (Penicillinase) (Cephalosporinase). Can hydrolyze carbapenem compounds. InterPro:IPR001279-Metallo-beta-lactamase superfamily TREMBL:Q8XRX8-72% identity TREMBL:Q7VUG6- 62% Pfam:PF00753-LactamaseB, Ribosomal proteinS6e,ThiC family TIGRFAM:TIGR00010- TatD/hisF family TMHMM predicted transmembrane helix. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity
YP_935185.1	Putative transcriptional regulator iclR-family,; Family membership
YP_935186.1	Putative periplasmic binding protein-related protein.This family includes several of which are involved in iron transport. 24%; Function unclear
YP_935187.1	Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices.; Family membership
YP_935188.1	Probable response regulator, HD. IPR003607; Met_phsphohydro. IPR001789; Response_reg. IPR008328; Res_reg_HDGYP. Pfam: PF01966; HD. PF00072; Response_reg. SMART: SM00471; HDc. SM00448; REC.; Specificity unclear
YP_935189.1	Putative cytochrome c4. Homology to cc4 of A. vinelandii of 29% (sprot|CYC4_AZOVI). Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems. Pfam: cytochrome C signal peptide no TMHs
YP_935190.1	Conserved hypothetical protein. Homology to pspto0091 of P. syringae of 35% (trembl|Q88BC6). Pfam: DUF861. This family consists of several proteins which seem to be specific to plants and bacteria. The function of this family is unknown. no signal peptide. no TMHs
YP_935191.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_935192.1	Conserved hypothetical membrane protein. Homology to atu1643 of A. tymefaciens of 39% (trembl|Q8UEW1(SRS)). Pfam: Bacterial transmembrane pair family. This domain represents a conserved pair of transmembrane helices. It appears to be found as two tandem repeats in a family of hypothetical proteins. signal peptide. 3 TMHs; Conserved hypothetical protein
YP_935193.1	Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Family membership
YP_935194.1	Putative N-acetyltransferase,51% Identity to TrEMBl;Q7WQB1,54% Identity to TrEMBL;Q63LT2,Q7WCA7. Has PF00583, Acetyltransferase (GNAT) family;IPR000182,GCN5acetyl_trans; This family contains proteins with N-acetyltransferase functions. Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of chromatin, histones tend to be hyperacetylated, whereas in transcriptionally silent regions histones are hypoacetylated. The histone acetyltransferases are divided into five families. These include the Gcn5-related acetyltransferases (GNATs); the MYST (for `MOZ, Ybf2/Sas3,Sas2 and Tip60)-related HATs; p300/CBP HATs; the general transcription factor HATs, which include the TFIID subunit TAF250; and the nuclear hormone-related HATs SRC1 and ACTR (SRC3). The GCN5-related N-acetyltransferase superfamily includes such enzymes as the histone acetyltransferases GCN5 and Hat1, the elongator complex subunit Elp3, the mediator-complex subunit Nut1, and Hpa2
YP_935195.1	Similar to hypothetical integral membrane transport protein yidY (MFS family). Signal peptide containing non secretory protein. With 12 putative transmembrane helices. General transport of carbohydrates , amino acids, and other small molecules.; Conserved hypothetical protein
YP_935196.1	Hypothetical secreted protein. No good homology to the data bank. Has Signal Peptide.
YP_935197.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_935198.1	Conserved hypothetical secreted protein. Homology to bb3068 of B. bronchiseptica of 31% (trembl|Q7WHY8(SRS)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_935199.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Has signal peptide.
YP_935200.1	Conserved hypothetical protein. Homology to Daro03001371 of Dechloromonas aromatica of 43% (gi|53730748|ref|ZP_00348943.1|(NBCI ENTREZ)). No doamins predicted. No signal peptide. No TMHs.
YP_935201.1	Conserved hypothetical protein, 38% identity(51% similarity) to TrEMBL;Q8KAU5. TrEMBL; Q6MRD6(59% identity). Has PF07075, Protein of unknown function (DUF1343);IPR008302, UCP016719; This family consists of several hypothetical bacterial proteins of around 400 residues in length. The function of this family is unknown.There are currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function.; Function unclear
YP_935202.1	Probable thioredoxin-disulfide reductase. Homology to trxC3 (THI3_CORNE) of C. nephridii of 43%. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Pfam: Thioredoxin no signal peptide no TMHs; Family membership
YP_935203.1	Conserved hypothetical protein. Homology to bll7423 of B. japonicum of 53% (trembl|Q89DL6). Pfam: Antibiotic biosynthesis monooxygenase. no TMHs. No signal peptide.
YP_935204.1	conserved hypothetical protein. Homology to Avin02001428 of Azotobacter vinelandii of 54% (gi|53612536|ref|ZP_00091632.2|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs
YP_935205.1	Conserved hypothetical membrane protein. Homology to PM2013 of P. multocida of 44% (tremble:Q9CJJ4). probable signal peptide. probable 2 TMHS; Conserved hypothetical protein
YP_935206.1	Hypothetical membrane protein. No homology of the entire protein to the data bank. Has PF05875;Alkaline phytoceramidase (aPHC):This family consists of several eukaryotic Alkaline phytoceramidase (aPHC) sequences. Ceramidases are enzymes involved in regulating cellular levels of ceramides, sphingoid bases, and their phosphates. Alkaline phytoceramidase (aPHC) is responsible for the hydrolysis of phytoceramide. No signal peptide. 6 TMHs.
YP_935207.1	Putative AraC family transcriptional regulator,; High confidence in function and specificity
YP_935208.1	Similar to TREMBL:Q89RW7 (50% identity,64% similarity); TREMBL:Q88IS2 (49% identity). InterPro (IPR000051); SAM (and some other nucleotide) binding motif.
YP_935209.1	Conserved hypothetical protein. Homology to sty1393 of S. typhi of 34% (trembl|Q8Z792). Pfam: Antibiotic biosynthesis monooxygenase. no signal peptide. no TMHs
YP_935210.1	Dioxygenases catalyze the incorporation of both atoms of molecular oxygen into substrates. Cleavage of aromatic rings is one of the most important function of dioxygenases. Similar to trembl|Q7WJ14 (50%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Family membership
YP_935211.1	Family membership; ORF8
YP_935212.1	Conserved hypothetical transferase. Homology to the IAA acetyltransferase of A. brasilense of 37% (sprot|IAAT_AZOBR). The IAA acetyltransferase participates in the tryptophan-dependent indole-3-acetic acid production, which is a phytohormone released by A.brasilense. Interpro: GCN5-related N-acetyltransferase (IPR000182). Pfam: Acetyltransferase (GNAT) family. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935213.1	Similar to SWISSPROT:P39367 (68% identity),TREMBL:Q8Z1C8 (66% identity).
YP_935214.1	conserved hypothetical protein. Homology to Raeut03002407 of Ralstonia eutropha of 48% (gi|46132577|ref|ZP_00171131.2|(NBCI ENTREZ)). Pfam: NUDIX domain. No signal peptide. No TMHs.
YP_935215.1	Bleomycin (Blm) is a glycopeptide antibiotic produced naturally by actinomycetes. It is a strong DNA-cutting agent and thus finds use as a potent anti-cancer drug. Actinomycetes have developed a defence mechanism against this lethal compound, producing a protein that confers resistance to Blm through drug sequestering.Putative Bleomycin resistance protein,; Family membership
YP_935216.1	Probable Acetyltransferase. Has weak homology with hits in the database, TrEMBL;Q7N1H0(56% Identity). Has PF00583, Acetyltransferase (GNAT) family; IPR000182, GCN5acetyl_trans; This family contains proteins with N-acetyltransferase functions.;Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of chromatin, histones tend to be hyperacetylated, whereas in transcriptionally silent regions histones are hypoacetylated. The histone acetyltransferases are divided into five families. These include the Gcn5-related acetyltransferases (GNATs); the MYST (for `MOZ, Ybf2/Sas3,Sas2 and Tip60)-related HATs; p300/CBP HATs; the general transcription factor HATs, which include the TFIID subunit TAF250; and the nuclear hormone-related HATs SRC1 and ACTR (SRC3). The GCN5-related N-acetyltransferase superfamily includes such enzymes as the histone acetyltransferases GCN5 and Hat1, the elongator complex subunit Elp3, the mediator-complex subunit Nut1, and Hpa2; Family membership
YP_935217.1	Hypothetical membrane protein. Homology to an orf of E. coli of 29% (trembl|Q8VNQ4). no domains predricted. no signal peptide. 3 TMHs
YP_935219.1	Region start changed from 4071796 to 4071769 (-27 bases), , Changed start from att to next atg
YP_935222.1	Putative truncated transposase for insertion sequence element IS1328. Required for the transposition of the insertion element (Potential). Homology only to the N-terminus.; Family membership
YP_935223.1	Putative truncated transposase for insertion sequence element IS1328. Required for the transposition of the insertion element (Potential). InterPro: Transposase IS116/IS110/IS902 family. Homoloy only to the C-terminus.; Specificity unclear
YP_935224.1	Hypothetical protein, Has very weak or no homologs in the Database. Has No domains, repeats, motifs or features predicted above threshold score.
YP_935225.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_935226.1	Truncated integrase/recombinase, probably Integrase/recombinase. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus
YP_935227.1	Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus.; Family membership
YP_935228.1	one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity
YP_935229.1	Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present.; Conserved hypothetical protein
YP_935230.1	Probable lipoprotein, 58% similarity to TrEMBL:Q8XWT8 PROBABLE LIPOPROTEIN [RS01163] [Ralstonia solanacearum (Pseudomonas solanacearum)]. Has PF04355:IPR007450:SmpA / OmlA family;Lipoprotein Bacterial outer membrane lipoprotein, possibly involved in in maintaining the structural integrity of the cell envelope [1]. Lipid attachment site is a conserved N terminal cysteine residue. Sometimes found adjacent to the OmpA domain (OmpA). Signal peptide present. NO TMH reported present.; Family membership
YP_935231.1	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to sprot|LIVK_ECOLI (31%) and to trembl|Q7NV64 (54%). Pfam (PF01094): Receptor family ligand binding region Pfam (PF00861): Ribosomal L18p/L5e family SignalP reporting Signal peptide.; Specificity unclear
YP_935232.1	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to trembl|Q7NV64 (58%) and to sprot|LIVK_ECOLI (33%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_935233.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar trembl|Q7NXX3 (60%), to sprot|BRAD_PSEAE (47%) and to sprot|LIVH_ECOLI (44%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting seven Tmhelix. gntP: gluconate transporter; Specificity unclear
YP_935234.1	Putative branched-chain amino acid transport permease. Homology to livM of S. typhimurium of 44%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. no signal peptide probable 8 TMHs; Specificity unclear
YP_935235.1	Probable high-affinity branched-chain amino acid transport ATP-binding protein BraF. ATP-binding cassette (ABC) transporters are multidomain membrane proteins,responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. BraF is a COMPONENT OF THE HIGH AFFINITY LEUCINE ISOLEUCINE VALINE TRANSPORT SYSTEM (LIV-I) WHICH IS OPERATIVE WITHOUT NA(+) AND IS SPECIFIC FOR ALANINE AND THREONINE IN ADDITION TO BRANCHED-CHAIN AMINO ACIDS. Similar to trembl|Q7NXX1 (67%), to sprot|BRAF_PSEAE (45%) and to sprot|LIVG_ECOLI (44%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear
YP_935236.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7NXX0 (58%) and to trembl|Q7VVD3 (59%). Smart: AAA ATPases; Specificity unclear
YP_935237.1	Bicyclomycin resistance protein homolog. Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). InterPro: General carbohydrate, amino acid , and divalent cation transport. Occurence of signal peptide and 12 transmembrane helices. Presence of DUF domains and Cation transport ATPase C-terminus domains. 35% identity and 47% similarity to bcr from X.axonopodis. Probably it is a copy of bcr1 in Azoarcus BH72 genome.; Conserved hypothetical protein
YP_935238.1	Conserved hypothetical protein. Homology to rsc0338 of R. solanacearum of 64% (trembl|Q8Y2J7). Probable Mg(2+) chelatase family protein. InterPro: Mg chelatase-related protein (IPR004482); MCM family (IPR001208); AAA ATPase superfamily (IPR003593); Magnesium chalatase, chlI subunit (IPR000523); TypeI antifreeze protein (IPR000104). no signal peptide. no TMHs. TIGR00368: Mg chelatase-related protein; Family membership
YP_935239.1	Conserved hypothetical protein. Homology to NE0192 of N.europaea of 52% (trembl:Q82XR2). Has PF04380, Protein of unknown function (DUF526);IPR007475 ;This is a family of uncharacterised proteins. No signal peptide. No TMHs.
YP_935240.1	Conserved hypothetical secreted protein. Homology to rsc0341 of R. solanacearum of 40% (trembl|Q8Y2J4(SRS)). no domains predicted. signal peptide. no TMHs
YP_935241.1	PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ3 (100%) and to trembl|Q7NQY3 (87%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity
YP_935242.1	Ammonium transporter 1 member 1 (AtAMT1;1). Involved in high affinity ammonium uptake. TREMBL:Q8RP89: 100% identity (published) InterPro:IPR001905; Ammonium_transpt. IPR002229; RhesusRHD. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp PRINTS PR00342; RHESUSRHD. TIGRFAMs TIGR00836; amt; PROSITE: PS01219; AMMONIUM_TRANSP SignalP predicted signal peptide present (0.997 probability). TMHMM predicted 12 transmembrane helices; High confidence in function and specificity
YP_935243.1	Outer membrane protein W precursor. Acts as a receptor for colicin S4.; High confidence in function and specificity
YP_935244.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
YP_935245.1	catalyzes the formation of serine from phosphoserine; also has phosphoserine:homoserine phosphotransferase activity
YP_935246.1	HD-domain containing protein,; Conserved hypothetical protein
YP_935247.1	ABC transporter ATP-binding protein yheS. Nonsecretory protein with Signal peptide. Presence of oxidoreductase Molybdopterin binding domain, M-protein repeats, RecF protein domains, Cu amine oxidase N3 domain,K+ channels and iron-sulphur binding potentials.57% identity and 68% similarity to Dechloromonas ATPase component of ABC transporter ureG: urease accessory protein UreG; Family membership
YP_935248.1	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide no TMHs
YP_935249.1	Catalyzes the isomerization of 2-hydroxychromene-2-carboxylate (hcca) to trans-o-hydroxybenzylidenepyruvate (thbpa). Upper napthalene catabolic pathway which involves conversion of napthalene to salicylate. Similar to TREMBL:Q7WEK4 (57% identity); TREMBL:Q9I714 (35% identity); SWISSPROT:Q51948 (29% identity). InterPro: 2-hydroxychromene-2-carboxylate isomerase Pfam (HCCA_isomerase): 2-hydroxychromene-2-carboxylate isomerase.; Specificity unclear
YP_935250.1	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs
YP_935251.1	Probable HTH-type transcriptional activator ampR. Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (ampC) in the presence of beta-lactams and induces it in the absence of them. Similar to SWISSPROT: sprot|AMPR_PSEAE (34% Pseudomonas aeruginosa,HTH-type transcriptional activator AmpR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_935252.1	This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoatesynthase catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate. Similar to TREMBL:Q7NWS7 (61% identity); TREMBL:Q8UIM8 (57% identity); TREMBL:Q89UX3 (33% identity). InterPro (IPR000868): Isochorismatase hydrolase. Pfam (PF00857): Isochorismatase family.; Family membership
YP_935253.1	Probable AraC family transcriptional regulator,; High confidence in function and specificity
YP_935254.1	Conserved hypothetical membrane protein. Homology to RSC0519 of R. solanacearum of 51%. InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter. Pfam: Integral membrane protein DUF6. probable signal peptide. probable 9 TMHs; Conserved hypothetical protein
YP_935255.1	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain
YP_935256.1	Putative thiamine biosynthesis lipoprotein ApbE. Homology to apbE of Salmonella typhimurium of 27% (gi|5915687|sp|P41780|APBE_SALTY(NBCI ENTREZ)). Pfam: ApbE family. This prokaryotic family of lipoproteins are related to ApbE from Salmonella typhimurium. ApbE is involved in thiamine synthesis. More specifically is may be involved in the conversion of aminoimidazole ribotide (AIR) to 4-amino-5-hydroxymethyl-2-methyl pyrimidine (HMP). No TMHs. Signal peptide present.; Family membership
YP_935257.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
YP_935258.1	glutamate--cysteine ligase. Glutathione metabolism.; High confidence in function and specificity
YP_935259.1	Modification methylase TaqI (EC 2.1.1.72) (Adenine-specific methyltransferase TaqI) (M.TaqI). THIS METHYLASE RECOGNIZES THE DOUBLE-STRANDED SEQUENCE TCGA CAUSES SPECIFIC METHYLATION ON A-4 ON BOTH STRANDS AND PROTECTS THE DNA FROM CLEAVAGE BY THE TAQI ENDONUCLEASE. InterPro: N6 adenine-specific DNA methyltransferase N12 class; Family membership
YP_935260.1	DcrH:hemerythrin protein, is transmembrane methyl-accepting protein probably involved in bacterial chemotaxis . 32% Hemerythrin. Pfam:PF01814; Hemerythrin; 1.; High confidence in function and specificity
YP_935261.1	Hemerythrin family protein, 38% Identity to TrEMBl:Q74G47,35% to TrEMBL; Q73NY7. Has PF01814,Hemerythrin HHE cation binding domain; IPR002063 Hemerythrin; Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor P80255 binds Cadmium so as to protect the organism from toxicity ([3]). However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96 is a regulator of response to NO, which suggests yet another set-up for its metal ligands . In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.
YP_935262.1	Hypothetical secreted protein. No good homology of the entire protein to the data bank. Has PF06097,Bacterial protein of unknown function (DUF945);IPR010352; This family consists of several hypothetical bacterial proteins of unknown function. No TMHs Siganl peptide present.
YP_935263.1	Conserved hypothetical protein. Homology to ebD78 of Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebD78(KEGG)). no domains predicted. no signal peptide. no TMHs
YP_935264.1	Hypothetical patatin-like protein. Homology to all2302 of Anabaena sp. of 20% (trembl|Q8YUN7). Pfam: Patatin. PATATIN MAY HAVE A DUAL ROLE AS A SOMATIC STORAGE PROTEIN AND AS AN ENZYME INVOLVED IN HOST RESISTANCE. THIS TUBER PROTEIN REPRESENTS APPROXIMATELY 40% OF THE TOTAL PROTEIN IN MATURE TUBERS. InterPro: Patatin (IPR002641). no signal peptide. no TMHs
YP_935265.1	Hypothetical protein. no homology to the data bank no domains no signal peptide no TMHs
YP_935266.1	Hypothetical 21.1 kDa protein in fasciation locus (ORF6). TREMBL:Q8FV26: 50% identity, 65% similarity InterPro:IPR005269; Cons_hypoth730. Pfam:PF03641; Lysine_decarbox L18_bact: ribosomal protein L18 Absence of signal peptide (Signal P predicted) Absence of transmembrane helices (TMHMM predicted); Specificity unclear
YP_935267.1	Probable GTP cyclohydrolase II. TIGRFAM: ribA: GTP cyclohydrolase II; Function unclear
YP_935268.1	Conserved hypothetical protein. Homology to blr7238 of B.japonicum of 48% (trembl:Q89E49). No domains predicted. No TMHs. Signal peptide with a probability of 0.570.
YP_935269.1	Uracil phosphoribosyltransferase. (UMP pyrophosphorylase) (UMP diphosphorylase); High confidence in function and specificity
YP_935270.1	Region start changed from 4129741 to 4129603 (-138 bases)
YP_935271.1	Catalyzes the deamination of cytosine to uracil and ammonia
YP_935272.1	conserved hypothetical protein, 43% identity (60% similarity) to TrEMBL; Q8ZML9. TrEMBL;Q8X937(44% identity to Escherichia coli) Has PF04972, Putative phospholipid-binding domain;IPR007055, TAD; This domain is found in a family of osmotic shock protection proteins (e.g. P27291). It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. Has SMART;SM00257,LysM, Lysin motif:IPR002482; This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.
YP_935273.1	Probable Hypothetical protein AQ_1494. TREMBL:Q7NVG8: 46% identity, 64% similarity. InterPro:IPR006684; 4HBcoA_thiostrse. IPR006683; Thioestr_supf. Pfam PF03061; 4HBT TIGRFAMs; TIGR00051; 4HBcoA_thiostrse TIGR00051: conserved hypothetical protein No signal peptide. No transmembrane helices.; Function unclear
YP_935274.1	Hypothetical protein yhiN. TREMBL:Q7NU52: 55% identity, 66% similarity InterPro; IPR001327; FAD_pyr_redox. InterPro; IPR004792; HI0933_like. InterPro; IPR000719; Prot_kinase. InterPro; IPR001100; Pyr_redox InterPro: HI0933-like protein TIGR00275: conserved hypothetical pro Pfam PF03486; HI0933_like Non-secretory protein with no signal peptide (SignalP predicted) No transmembrane helices (TMHMM predicted); Function unclear
YP_935275.1	Conserved hypothetical secreted protein. Homology to Daro03002424 of Dechloromonas aromatica of 32% (gi|41723837|ref|ZP_00150727.1|(NBCI ENTREZ)). Pfam: OmpA family. singal peptide. no TMHs
YP_935276.1	Putative serine/threonine-protein kinase (EC 2.7.11.1). Pfam: Protein kinase domain; Family membership
YP_935277.1	Collagenase and related proteases. Homology to ne1979 of N. europaea of 63% (trembl|Q82TC1). InterPro: Peptidase family U32 (IPR001539). Pfam: Peptidase family U32 no signal peptide no TMHs; Family membership; ORF9
YP_935278.1	Conserved hypothetical membrane protein. Homology to ebA2790 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA2790(KEGG)). No domains predicted. no signal peptide. 2 TMHS; Conserved hypothetical protein
YP_935279.1	GGDEF family protein,; Conserved hypothetical protein
YP_935280.1	Putative streptothricin acetyltransferase. Homology to staT of S. lavenduale (sprot|STA_STRLA). Pfam: Acetyltransferase (GNAT) family. no signal peptide no TMHs; Family membership
YP_935281.1	Hypothetical ABC transporter ATP-binding protein ybiT. Probably involved in the transport of Cobalt,branched chain amino acids , or multi drug resistance. Occurence of tub domains, uridine kinase domain, DUF and RecF protein like domains. Signal P present. Central region; Family membership
YP_935282.1	This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. The IICD domains contain the sugar binding site and the transmembrane channel; the IIA domain contains the primary phosphorylation site (the donor is phospho-HPr); IIA transfers its phosphoryl group to the IIB domain which finally transfers it to the sugar. 32% EIIA-man.IPR004720; PTSIIB_sorb. Pfam:PF03610; EIIA-man; 1.PF03830; PTSIIB_sorb; 1.; Specificity unclear
YP_935283.1	Phosphocarrier protein HPr (Histidine-containing protein) (Protein H). This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). HPr is common to all PTS (By similarity). 64% HPr_HisP_S.IPR000032; HPr_protein.IPR002114; HPr_SerP_S. IPR005698; PTS_HPr. Pfam:PF00381; PTS-HPr; 1.; High confidence in function and specificity
YP_935284.1	Phosphoenolpyruvate-protein phosphotransferase(Phosphotransferase system enzyme I)(Protein I).This is a component of the phosphoenolpyruvate dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Enzyme I is common to all PTS. 54% PEP-utilisers_N.IPR008279; PEP_mobile.IPR006318; PEP_P_trans.IPR000121; PEP_utilizers. Pfam:PF05524; PEP-utilisers_N; 1.PF00391; PEP-utilizers; 1.PF02896; PEP-utilizers_C; 1. TIGRFAMs:TIGR01417; PTS_I_fam; 1.; High confidence in function and specificity
YP_935285.1	Conserved hypothetical secreted protein. Homology to Daro03001609 of Dechloromonas aromatica of 35% (gi|53730883|ref|ZP_00151781.2|(NBCI ENTREZ)). No domains predicted. Signal peptide present. No TMH reported Present.; Conserved hypothetical protein
YP_935286.1	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. TMH in signal peptide
YP_935288.1	Ferredoxin hydrogenase, small subunit. Homology to hoxK of A. eutrophus of 83% (sprot:MBHS_ALCEU). This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions. Tigrfam: hydA: hydrogenase (NiFe) small subunit Pfam: NADH ubiquinone oxidoreductase 20kD signal peptide no TMHs; High confidence in function and specificity
YP_935289.1	Probable ferredoxin hydrogenase, large subunit. Homology to hoxG of A. eutrophus of 68% (>sprot|MBHL_ALCEU). This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions. Pfam: Nickel dpendent hydrogenase no signal peptide no TMHs; High confidence in function and specificity
YP_935290.1	Probable Ni/Fe-hydrogenase, B-type cytochrome subunit. Homology to hupZ of A. chroococcum of 65% (sprot|CYBH_AZOCH) Probable b-type cytochrome. InterPro: Nickel-dependent hydrogenase b-type cytochrome subunit (IPR000516) Pfam: Nickel-dependent hydrogenase b-type cytrochrome subunit no signal peptide 4 TMHs; High confidence in function and specificity
YP_935291.1	Conserved hypothetical protein. Homology to ne1110 of N. europaea of 35% (trembl|Q82VH8). InterPro: Helix-turn-helix motif (IPR0001387). Pfam: Helix-turn-helix. no signal peptide. no TMHs
YP_935292.1	Conserved hypothetical glutathione peroxidase. Homology to gpwA of P. wisconsinensis of 52% (SWISSPROT:GPWA_PSEWI). Glutathione peroxidase (GSHPx), an enzyme whose principal function is to protect against damage from endogenously-formed hydroxyperoxides,catalyses the reduction of hydroxyperoxides by glutathione. InterPro: Glutathione peroxidase (IPR000889),Type I antifreeze protein (IPR000104). Pfam: Glutathione peroxidase. signal peptide. no TMHs; Family membership
YP_935293.1	Conserved hypothetical ATPase. Homology to MCA0262 of Methylococcus capsulatus of 68% (gi|53756248|gb|AAU90539.1|(NBCI ENTREZ)). InterPro: AAA-protein (ATPases associated with various cellular activities) (IPR003959);AAA ATPase superfamily (IPR003593) Pfam: ATPase family associated with various cellular activities (domaine from 365 aa to 540 aa) no signal peptide. no TMHs.; Function unclear
YP_935294.1	Hydrogenase expression/formation protein hupD, 54% identity,(63% simialrity) to SwissProt:Q03004. Aliases: hoxM(SwissProt:P40591), hyaD(E.coli). Has PF01750:Hydrogenase maturation protease;The family consists of hydrogenase maturation proteases. In E. coli HypI the hydrogenase maturation protease is involved in processing of HypE the large subunit of hydrogenases 3, by cleavage of its C-terminal. IPR000671:Peptidase_M52; TIGR00072; hydrog_prot; Signal P reporting SIgnal peptide Present. No TMH present.; High confidence in function and specificity
YP_935295.1	Putative Hydrogenase expression/formation protein hupF,43% similarity to TrEMBL; Q6PTB2. No Signal Peptide or TMH reported present. Has PF01455:HupF/HypC family(IPR001109);The large subunit of [NiFe]-hydrogenase,as well as other nickel metalloenzymes, is synthesized as a precursor devoid of the metalloenzyme active site. This precursor then undergoes a complex post-translational maturation process that requires a number of accessory proteins. The hydrogenase expression/formation proteins (HUPF/HYPC) form a family of small proteins that are hydrogenase precursor-specific chaperones required for this maturation process . They are believed to keep the hydrogenase precursor in a conformation accessible for metal incorporation.; High confidence in function and specificity
YP_935296.1	Hydrogenase-1 operon protein HyaE, 50% similarity to TrEMBL;Q8XGC7, 46% similarity to SwissProt;P19931. Alias: hupG Has PF07449:Hydrogenase-1 expression protein HyaE(IPR010893);This family contains bacterial hydrogenase-1 expression proteins approximately 120 residues long. This includes the E. coli protein HyaE, and the homologous proteins HoxO of R. eutropha and HupG of R. leguminosarum. Deletion of the hoxO gene in R. eutropha led to complete loss of the uptake [NiFe] hydrogenase activity, suggesting that it has a critical role in hydrogenase assembly. No signal peptide or TMH reported present.; High confidence in function and specificity
YP_935297.1	Hydrogenase expression/formation protein hupH, 58% similarity to SwissProt:Q03007. TrEMBL;Q6PTB0,TrEMBL;P95499, SwissProt;P19932. Has PF04809(IPR006894):HupH hydrogenase expression protein, C-terminal conserved region;This family represents a C-terminal conserved region found in these bacterial proteins necessary for hydrogenase synthesis. Their precise function is unknown. No Signal peptide or TMH reported Present.; High confidence in function and specificity
YP_935298.1	Probable rubredoxin protein, 61% Identity to SProt;P30778, P31912. Has PF00301, Rubredoxin;Rubredoxin is a low molecular weight iron-containing bacterial protein involved in electron transfer,sometimes replacing ferredoxin as an electron carrier. No signal peptide. No TMHs.; High confidence in function and specificity
YP_935299.1	Probable Hydrogenase expression/formation protein hupJ, 52% similarity to SwissProtP28152. Alias:hybE No Signal Peptide or TMH reported present. thiM: hydroxyethylthiazole kinase
YP_935300.1	Putative hydrogenase expression/formation protein HupK. Homology to hupK of R. leguminosarum of 33% (gi|48731|emb|CAA37158.1|(NCBI ENTREZ). No domains predicted. No signal peptide or TMH present., ,; Family membership
YP_935301.1	Hydrogenase nickel incorporation protein hypA. Homology to hypA2 of A. eutrophus of 50% (AAB60888). Probably plays a role in an hydrogenase nickel cofactor insertion step. Pfam: Hydrogenase eypression/synthesis hypA Tigrfam: hypA: hydrogenase expression/formation protein no TMHs; High confidence in function and specificity
YP_935302.1	Probable hydrogenase accessory protein HypB. Homology to hypB of E. coli of 56% (sprot|HYPB_ECOLI). IS REQUIRED FOR THE FORMATION OF HYDROGENASE ISOENZYMES. AFFECTS SOME ASPECT OF THE PROCESSING OF HYDROGENASES and NICKEL INCORPORATION scince HYPB GENE LESIONS CAN BE COMPLEMENTED BY HIGH NICKEL ION CONCENTRATION IN THE MEDIUM. Pfam: HypB/UreG nucleotide-binding domain Tigrfam: hypB: hydrogenase accessory protein Hyp no signal peptide no TMHs; High confidence in function and specificity
YP_935303.1	probable hydrogenase maturation protein HypF. Homology to hypF2 of A. eutrophus of 58% (sprot|HYF2_ALCEU). Involved in the hydrogenase maturation process. InterPro: Hydrogenase maturation protein HypF (IPR00421), SuA5/yciO/yrdC family (IPR004388); Acylphosphatase (IPR001792) Pfam: Acylphosphatase, yrdC domain Tigrfam: hypF: hydrogenase maturation protein H no signal peptide no TMHs; High confidence in function and specificity
YP_935304.1	Probable hydrogenase assembly chaperon HypC. Homology to hypC of R. leguminosarum of 61% (sprot|HYPC_RHILV). Forms a family of small proteins that are hydrogenase precursor-specific chaperones required for this maturation process. They are believed to keep the hydrogenase precursor in a conformation accessible for metal incorporation. Pfam: HypF/HypC family Tigrfam: hypC_hupF: hydrogenase assembly chaperone no signal peptide no TMHs; Function unclear
YP_935305.1	Hydrogenase expression/formation protein hypD. Homology to hypD of A. eutrophus of 71% (sprot|HYPD_ALCEU). HypD is involved in hydrogenase formation. InterPro: Hydrogenase formation hypA (IPR002780) Pfam: Hydrogenase formation hypA family Tigrfam: hypD: hydrogenase expression/formation no signal peptide no TMHs; High confidence in function and specificity
YP_935306.1	Hydrogenase expression/formation protein hypE, 64% Identity to SProt;P31905,TrEMBL;Q6NB52(60% Identity),Q83WU6. Has PF00586, AIR synthase related protein, N-terminal domain;IPR000728 AIR_synth; This family includes Hydrogen expression/formation protein, HypE, which may be involved inthe maturation of NifE hydrogenase; AIR synthase and FGAM synthase, which are involved in de novo purine biosynthesis; and selenide, water dikinase, an enzyme which synthesizes selenophosphate from selenide and ATP. PF02769, AIR synthase related protein, C-terminal domain;IPR010918 AIR_synth_C; This entry includes Hydrogen expression/formation protein, HypE, which may be involved in the maturation of NifE hydrogenase; AIR synthase and FGAM synthase, which are involved in de novo purine biosynthesis; and selenide, water dikinase, an enzyme which synthesizes selenophosphate from selenide and ATP.
YP_935307.1	Hydrogenase transcriptional regulatory protein,; High confidence in function and specificity
YP_935308.1	Hypothetical protein, 33% Identity to TrEMBL;Q8XRA3 Has No domains, repeats, motifs or features could be predicted above threshold.
YP_935309.1	Ferredoxin hydrogenase, small subunit. Homology to hoxB of A. hydrogenophilus of 75% (TREMBL:P94154). Hydrogenases catalyse the reversible oxidation of molecular hydrogen and play a vital role in anaerobic metabolism. InterPro: Hydrogenase (NiFe) small subunit HydA (IPR001821); Respiroatory-chain NADH dehydrogenase 20 kD subunit (IPR006137) Tigrfam: hydA: hydrogenase (NiFe) small subunit (hydA) Pfam: NADH ubiquinone oxidoreductase no signal peptide no TMHs; High confidence in function and specificity
YP_935310.1	Probable ferredoxin hydrogenase, large subunit. Homology to hoxC of A. hydrogenophilus of 59% (trembl|P94155). InterPro: Nickel-dependent hydrogenases large subunit
YP_935311.1	Conserved hypothetical membrane protein,; Conserved hypothetical protein
YP_935312.1	Putative hydrogen uptake histidine-kinase,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR009082; His_kin_homodim. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. Pfam: PF02518; HATPase_c. PF00512; HisKA. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00086; PAC. SM00091; PAS.; High confidence in function and specificity
YP_935313.1	Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) (NTA monooxygenase component B) (NTA-MO B). HYDROXYLATION OF NITRILOTRIACETATE. TREMBL:Q7W4Q0: 46% identity, 65% similarity InterPro: Flavin reductase-like domain Interpro:IPR002563 Pfam:PF01613 No signal peptide No transmembrane helices monomer_idh: isocitrate dehydrogenase NA; High confidence in function and specificity
YP_935314.1	A/G-specific adenine glycosylase (EC 3.2.2.-). ADENINE GLYCOSYLASE ACTIVE ON G-A MISPAIRS. MUTY ALSO CORRECTS ERROR-PRONE DNA SYNTHESIS PAST GO LESIONS WHICH ARE DUE TO THE OXIDATIVELY DAMAGED FORM OF GUANINE: 78-DIHYDRO-8- OXOGUANINE.; Specificity unclear
YP_935315.1	Conserved hypothetical ATP-dependent protease La. Homology to rsc0402 of R. solanacearum of 44% (trembl|Q8Y2D4). N-terminal domain of the ATP-dependent protease La (LON), present also in other bacterial ORFs. InterPro: ATP-dependent protease La (LON) domain (IPR003111). Pfam: ATP-dependent protease La (LON) domain. no signal peptide. no TMHs; Conserved hypothetical protein
YP_935316.1	Probable aromatic acid decarboxylase (EC 4.1.1.-). InterPro: Flavoprotein ubiX: phenylacrylic acid decarboxylase; High confidence in function and specificity
YP_935317.1	Probable phasin. Homology to p8 of Sphingomonas sp. A1 of 49% (gi|51773776|dbj|BAD38885.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.,; Function unclear
YP_935318.1	Putative AraC family transcriptional regulator,; Family membership
YP_935319.1	Conserved hypothetical protein. Homology to slr1189 of Synechocystis of 43% (trembl|P74718). Pfam: Homocystein S-transferase. no signal peptide. no TMHs.
YP_935320.1	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to sprot|LIVK_SALTY (20%) and to tremblnew|CAE26678 (39%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear
YP_935321.1	Putative branched-chain amino acid transporter permease. Homology to livM of E. coli of 32%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system. signal peptide probable 10 TMHs; Specificity unclear
YP_935322.1	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q89C65 (46%), to sprot|LIVH_ECOLI (33%) and to sprot|BRAD_PSEAE (30%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting seven Tmhelix. SignalP reporting Signal peptide.; Specificity unclear
YP_935323.1	2-nitropropane dioxygenase precursor (EC 1.13.11.32) (Nitroalkane oxidase) (2-NPD). SPROT:Q01284: 28% identity, 44% similarity CATALYZES THE OXIDATION OF NITROALKANES TO PRODUCE THE CORRESPONDING CARBONYL COMPOUNDS. IT ACTS ON 2-NITROPROPANE BETTER THAN ON NITROETHANE AND 1-NITROPROPANE AND ANIONIC FORMS OF NITROALKANES ARE MUCH BETTER SUBSTRATES THAN ARE NEUTRAL FORMS. InterPro: 2-nitropropane dioxygenase InterPro; IPR004136; 2nprop_dioxygen. InterPro; IPR003009; FMN_enzyme. Pfam; PF03060; NPD thiE: thiamine-phosphate pyrophosphoryl Non-secretory protein with signal peptide probability:0.004 Absence of TMH's; High confidence in function and specificity
YP_935324.1	homopentamer; channel that opens in response to pressure or hypoosmotic shock
YP_935325.1	Hypothetical protein ycbL. TREMBL:Q7P1X5-63% identity. Interpro:IPR001279-Blactamase like Pfam-GlyoxylaseII family relationship. Phosphoribosylglycinamide synthetase,Respiratory chain NADH dehydrogenase; KH domain and RTX toxin acyltransferase family relationship. ispD: 4-diphosphocytidyl-2C-methyl-D-ery; High confidence in function and specificity
YP_935326.1	Inositol-1(or4)-monophosphatase 3IMPase3)(IMP3)(Inositol monophosphatase 3).Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. 26% Inositol_P. Pfam:PF00459; Inositol_P; 1.; High confidence in function and specificity
YP_935327.1	Part of the ABC transporter complex FbpABC involved in ferric import. Similar to the putative periplasmic-binding protein FbpA precursor in A. pleuropneumoniae. 39% SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:1 TMHelix:1; Specificity unclear
YP_935328.1	Ferric cations import ATP-binding protein fbpC (EC 3.6.3.30).Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import. Responsible for energy coupling to the transport system. 41% AAA_ATPase. IPR003439; ABC_transporter. Pfam: PF00005;ABC_tran; 1.; Specificity unclear
YP_935329.1	Region start changed from 4186498 to 4186630 (-132 bases)
YP_935330.1	Glycerol-3-phosphate regulon repressor. 26% HTH_DeoR. Pfam:PF00455; DeoR; 1. Nucleic acid binding motif, present.; High confidence in function and specificity
YP_935331.1	Probable ethanolamine ammonia-lyase (EC 4.3.1.7) large subunit. Homology to eutB of S. typhimurium of 50% (trembl|Q8XUQ9) Catalyzes the deamination of various vicinal amino- alcohols to oxo compounds. no signal peptide no TMHs; High confidence in function and specificity
YP_935332.1	Ethanolamine ammonia-lyase (EC 4.3.1.7) small subunit. Homology to eutC of S. typhimurium of 35% (sprot|EUTC_SALTY) catalyzes the deamination of various vicinal amino- alcohols to oxo compounds. no signal peptide no TMHs; High confidence in function and specificity
YP_935333.1	Conserved hypothetical secreted protein. Homology to rpa0361 of R. palustris off 67% (tremblnew|CAE25805). no domains predicted .signal peptide. TMH in signal peptide; Conserved hypothetical protein
YP_935334.1	Putative ABC-type tungstate transport system,permease component.; Function unclear
YP_935335.1	31% HTH_9; 1. InterPro: IPR003725; ModE:Molybdenum-binding protein N-terminal. ModE are involved in molybdenum transport.These proteins acts both as a repressor and activator of the mod and moa operons,respectively, depending on the properties of the binding site.; High confidence in function and specificity
YP_935336.1	Conserved hypothetical protein. Homology to vv12967 of V. vulnificus of 47% (trembl|Q8D8K5). Pfam: DUF1111. no signal peptide. no TMHs
YP_935337.1	Phosphoglycerate transport regulatory protein pgtC precursor.Required for pgtP expression it may act jointly with the pgtA/pgtB signaling proteins.29% SBP_bac_1: Bacterial extracellular solute-binding protein family 1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present.; High confidence in function and specificity
YP_935338.1	Probable Iron-regulated outer membrane TonB-dependent receptor. 35% TonB_receptor.IPR010917; TonB_recept_C.IPR010105; TonB_siderophor. Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide:present.; Function unclear
YP_935339.1	80% AAA_ATPase superfamily. IPR003439; ABC_transporter. IPR008995; MOP_like:molybdenum-pterin binding domain.IPR005116; TOBE. Pfam:PF00005; ABC_tran; 1.PF03459; TOBE; 1.; High confidence in function and specificity
YP_935340.1	72% BPD_transp.Binding-protein-dependent transport systems inner membrane component. Pfam:PF00528; BPD_transp; 1. TMHelix:6; High confidence in function and specificity
YP_935341.1	73% MolP_ABC_transpt.IPR000437; prok_lipoprot_S. IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR01256; modA; 1. Signal peptide: present.; High confidence in function and specificity
YP_935342.1	80% ModE.IPR004606; Mop.IPR008995; MOP_like.IPR005116; TOBE.Molybdenum-binding protein N-terminal. Pfam:PF02573; HTH_9; 1.PF03459; TOBE; 2. TIGRFAMs:TIGR00637; ModE_repress; 1:ModE molybdate transport.TIGR00638; Mop; 2.; High confidence in function and specificity
YP_935343.1	80% Mop.IPR008995;MOP_like.IPR005116;TOBE.InterPro: Molybdenum-pterin binding domain. Mop: molybdenum-pterin binding domain Pfam: PF03459; TOBE; 2. TIGRFAMs:TIGR00638; Mop; 2.; High confidence in function and specificity
YP_935344.1	39% AAA_ATPase superfamily. IPR003439; ABC_transporter. IPR008995; MOP_like:molybdenum-pterin binding domain.IPR005116; TOBE. Pfam:PF00005; ABC_tran; 1.PF03459; TOBE; 1.; High confidence in function and specificity
YP_935345.1	Putative exported protein.SignalP reporting signal peptice. Most likely cleavage site between pos. 27 and 28: AHA-AP; Function unclear
YP_935346.1	Region start changed from 4207859 to 4207739 (-120 bases)
YP_935347.1	36% BPD_transp.Binding-protein-dependent transport systems inner membrane component. Pfam:PF00528; BPD_transp; 1. TMHelix:5 Signal peptide:present; High confidence in function and specificity
YP_935348.1	23% MolP_ABC_transpt.IPR000437; prok_lipoprot_S. IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR01256; modA; 1. Signal peptide: present.; High confidence in function and specificity
YP_935349.1	conserved hypothetical protein. Homology to Daro03003735 of Dechloromonas aromatica of 35% (gi|41722661|ref|ZP_00149650.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.
YP_935350.1	Function unclear
YP_935351.1	GGDEF/EAL/PAS/PAC-domain containing protein
YP_935352.1	Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) (Exodeoxyribonuclease V 67 kDa polypeptide). EXHIBITS SEVERAL CATALYTIC ACTIVITIES INCLUDING ATP-DEPENDENT EXONUCLEASE ATP-STIMULATED ENDONUCLEASE ATP-DEPENDENT UNWINDING AND DNA-DEPENDENT ATPASE ACTIVITIES. STRAND CLEAVAGE OCCURS 5 TO 3 DURING THE UNWINDING OF DUPLEX DNA AT CHI SEQUENCES WHICH LOCALLY STIMULATE RECOMBINATION. InterPro: AAA ATPase superfamily; High confidence in function and specificity
YP_935353.1	Exodeoxyribonuclease V beta chain (EC 3.1.11.5) (Exodeoxyribonuclease V 135 KDA polypeptide). REQUIRED FOR EFFICIENT DNA REPAIR; IT CATALYZES THE UNWINDING OF DOUBLE-STRANDED DNA AND THE CLEAVAGE OF SINGLE- STRANDED DNA AND IT STIMULATES LOCAL GENETIC RECOMBINATION. ALL OF THESE ACTIVITIES REQUIRE CONCOMITANT HYDROLYSIS OF ATP.; High confidence in function and specificity
YP_935354.1	24% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present.; High confidence in function and specificity
YP_935355.1	Conserved hypothetical protein; Function unclear
YP_935356.1	2-5 RNA ligase (EC 6.5.1.-). Specifically ligates tRNA half-molecules containing nucleoside base modifications and shows a preference among different tRNA species. Acts in the absence of ATP to form a 2-5 phosphodiester linkage.
YP_935357.1	Alkaline phosphatase (EC 3.1.3.1) (ALP)is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH.It is found in nearly all living organisms,with the exception of some plants. 30% Alk_phosphtse.Alkaline phosphatase family Pfam:PF00245; alk_phosphatase; 1. Signal peptide present.; High confidence in function and specificity
YP_935358.1	Conserved hypothetical secreted protein. Homology to Avin02002740 of Azotobacter vinelandii of 66% (gi|23103854|ref|ZP_00090328.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHS; Conserved hypothetical protein
YP_935359.1	Function:- Could possibly oxidizes fatty acids using specific components (By similarity). Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:- IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 65/222 (29%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership
YP_935360.1	Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) (Exodeoxyribonuclease V 125 kDa polypeptide). EXHIBITS A WIDE VARIETY OF CATALYTIC ACTIVITIES INCLUDING ATP-DEPENDENT EXONUCLEASE ATP-STIMULATED ENDONUCLEASE ATP-DEPENDENT HELICASE AND DNA-DEPENDENT ATPASE ACTIVITIES.; High confidence in function and specificity
YP_935361.1	Putative transcriptional regulator, LysR family,; High confidence in function and specificity
YP_935362.1	Tartrate dehydrogenase catalyzes the reduction of tartrate to oxaloglycolate. Similar to sprot|TTUC_ECOLI (75%) and to sprot|TTUC_PSEPU (76%). Pfam (PF00180): Isocitrate and isopropylmalate dehydrogenases; High confidence in function and specificity
YP_935363.1	Hypothetical protein, 73% identity(87% similarity) to TrEMBL;Q8XU60. No domains, repeats, motifs or features not present.; Function unclear
YP_935364.1	Conserved hypothetical membrane protein. Homology to rsc2949 of R. solanacearum of 54% (trembl|Q8XV82(SRS)). Tigrfam: TIGR00427: conserved hypothetical protein. Pfam: Uncharacterised protein family. signal peptide. 5 TMHs
YP_935365.1	Conserved hypothetical protein. Homology to ebA2737 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA2737(KEGG)). no domains predicted. no signal peptide. no TMHs
YP_935366.1	Conserved hypothetical cytochrome c family protein. Homology to gsu2513 of G. sulfurreducens of 36% (tremblnew|AAR35886). Pfam: Cytochrome c. singal peptide. no TMHs; Conserved hypothetical protein
YP_935367.1	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 32% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. SWISSPROT:DHET_GLUOX:O05542.30%; High confidence in function and specificity
YP_935368.1	Conserved hypothetical secreted protein. Homology to GOX0515 of Gluconobacter oxydans of 36% (gnl|keqq|gox:GOX0515(KEGG)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein
YP_935369.1	Probable acetoin dehydrogenase, alpha subunit. Homology to acoA of C. magnum of 42% (trembl|Q46142) CATALYZES THE 26-DICHLOROPHENOLINDOPHENOL-DEPENDENT CLEAVAGE OF ACETOIN INTO ACETATE AND ACETALDEHYDE IN VITRO. THE ALPHA SUBUNIT IS PROBABLY THE CATALYTIC SUBUNIT OF THE ENZYME. Pfam: Dehydrogenase E1 component no signal peptide no TMHs; Family membership
YP_935370.1	Probable acetoin dehydrogenase, beta subunit. Homology to acoB of. A. eutrophus of 48% (sprot|ACOB_ALCEU) Probable TPP-dependent acetoin dehydrogenase, beta subunit. Homology to acoB of A. eutrophus of 41% (sprot|ACOB_ALCEU) Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde, in vitro. The beta subunit is probably not the catalytic subunit of the enzyme. InterPro: Transketolase (IPR005474) Pfam: Transketoase,pyridine binding domain ; Transketolase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity
YP_935371.1	Conserved hypothetical protein. Homology to oadh21d of H. volcanii of 33% (trembl|Q8U4T3). Pfam: Biotin-requiring enzyme. Interpro: Biotin/Lipoyl attachment (IPR000089). no signal peptide. no TMHs.
YP_935372.1	Hypothetical protein. Homology of the entire orf to the C-terminus of dihydrolipoamide acetyltransferase. Pfam: 2-0xo acid dehydrogenase acyltransferase no TMHs no signal peptide
YP_935373.1	Putative lipoate protein ligase, has weak homology with hits. 35% identity with TrEMBL;Q81M24,Q818P0. Has Signal peptide. Has PF03099, Biotin/lipoate A/B protein ligase family;IPR004143 BPL_LipA_LipB; This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Each organism probably has only one BPL. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine. Lipoate-protein ligase A (LPLA) catalyses the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes.
YP_935374.1	Conserved hypothetical secreted protein. Homology blr7490 of B.japonicum of 47% (trembl|Q89DE9(SRS)). No domains predicted .No TMHs. Signal peptide: present; Conserved hypothetical protein
YP_935375.1	Putative glucase dehydrogenase alpha subunit. Homology to gdhalspha of B. cepacia of 31% (trembl|Q8GQE7). Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear
YP_935376.1	Conserved hypothetical secreted protein.; Conserved hypothetical protein
YP_935377.1	Similar to SWISSPROT:P28614 (44% identity); TREMBL:Q9HWN4 (40% identity); TREMBL:Q92X60 (38% identity). Pfam (PF02954): Bacterial regulatory protein,Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; Family membership
YP_935378.1	Rhs family protein,vgrG 38% identity(54% similarity) to TrEMBL;Q747T8. TrEMBL;O52672. Signal Peptide Present. Has PF04524, Protein of unknown function,DUF586;IPR006533, Rhs_Vgr:This family contains a conserved region in several bacterial proteins of unknown function. These sequences represent the Vgr family of proteins,associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region,VGXXXXXX, found in the Vgr of Rhs classes G and E. Has PF06715, Gp5 C-terminal repeat (2 copies);IPR010609,Gp5_C:This repeat composes the C-terminal part of the bacteriophage T4 baseplate protein Gp5. This region of the protein forms a needle like projection from the baseplate that is presumed to puncture the bacterial cell membrane. Structurally three copies of the repeated region trimerise to form a beta solenoid type structure. This family also includes repeats from bacterial Vgr proteins.
YP_935379.1	Conserved hypothetical protein. Homology to GSU3186 of G.sulfurreducens of 36% (tremblnew|AAR36577(SRS)). No domains predicted. No TMHs. No signal peptide.
YP_935380.1	Region start changed from 4252363 to 4252411 (-48 bases)
YP_935381.1	Hypothetical protein predicted by Glimmer/Critica. no homology of the entier protein to the data bank. no domains predicted. no signal peptide. no TMHs
YP_935382.1	Hypothetical protein. Homology to LA1152 of L.interrogans of 28% (trembl:Q8F6Z6). No domains predicted. No signal peptide. No TMHs
YP_935383.1	Conserved hypothetical protein. Homology to GSU3182 of G.sulfurreducens of 42% (tremblnew|AAR36573(SRS)). No domains predicted. No TMHs. No signal peptide.
YP_935384.1	Hypothetical protein, 40% similarity to TrEMBL: O86588. No domains, repeats, motifs or features predicted present.; Function unclear
YP_935385.1	Hypothetical protein,35% identity(53% similarity) to TrEMBL;Q9I731. Very Poor homology with hits in the database over the entire length of protein! No Signal peptide or TMH reported Present.; Family membership
YP_935386.1	Hypothetical regulatory protein,; Conserved hypothetical protein
YP_935387.1	Putative phosphoprotein phosphatase,; Conserved hypothetical protein
YP_935388.1	Hypothetical secreted protein. Homology to cv1891 of C. violaceum of 27% (TrEMBL:Q7NWT8). no domains predicted. signal peptide. no TMHs
YP_935389.1	Hypothetical secreted protein. no Homology of the entiere protein to the data bank. no domains predicted. singal peptide. no TMHs
YP_935390.1	Serine/threonine-protein kinase pknA (EC 2.7.11.1). Probably required for both normal cellular growth and differentiation. Inactivation of pknA leads to colonies that appear light green and rough in the absence of combined nitrogen. Pfam: Protein kinase domain; Family membership
YP_935391.1	Conserved hypothetical protein. Homology to PA0076 of P.aeruginosa of 38% (trembl:Q9I756). No domains predicted. No TMHs. No signal peptide.
YP_935392.1	Conserved hypothetical ImcF-related protein. Homology to BPP0730 of Bordetella parapertussis of 45% (gnl|keqq|bpa:BPP0730(KEGG)). Has Signal Peptide. TMHMM2 reporting 2 TMH's present. Coils2 Program reporting presence of Coiled-Coil. Has PF06761, ImcF-related;IPR009612; This family represents a conserved region within several bacterial proteins that resemble ImcF, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation, resulting in increased adherence to epithelial cells and increased conjugation frequency. Note that many family members are hypothetical proteins. Has PF06744, Protein of unknown function (DUF1215);IPR010623; This family represents a conserved region situated towards the C-terminal end of several hypothetical bacterial proteins of unknown function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency.; Conserved hypothetical protein
YP_935393.1	Putative outer membrane protein, OmpA family,36% identity(51%similarity) to TrEMBL;Q93IS0.TrEMBL;Q7AXY6(36% identity) TMHMM2 reporting presence of 1 TMH's. Has PF00691, OmpA family;IPR006665, OmpA/MotB:Most of the bacterial outer membrane proteins in this group are porin-like integral membrane proteins (such as ompA) MEDLINE:,but some are small lipid-anchored proteins.It is also found in MotB and related proteins. They are present in the outer membrane of many Gram-negative organisms.; Conserved hypothetical protein
YP_935394.1	Conserved hypothetical protein,40% Identity (57% similarity)to TrEMBL;Q93EC4 Has PF05936, Bacterial protein of unknown function (DUF876);IPR010263;This family consists of a series of hypothetical bacterial sequences of unknown function.
YP_935395.1	Conserved hypothetical secreted protein. Homology to PA1666 of P.aeruginosa of 37% (trembl|Q9I359(SRS)). Signal peptide present. No TMH or any other domains/features reported present.; Conserved hypothetical protein
YP_935396.1	Putative cytoplasmic protein,sciA. TrEMBL;Q83SK5 ,Q7AXZ5 Has PF06812, ImpA-related N-terminal;IPR010657,ImpA_N;This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. Note that many family members are hypothetical proteins.; Conserved hypothetical protein
YP_935397.1	Putative cytoplasmic protein,sciH, 71% identity(87% similarity) to TrEMBL;Q7AXZ1. Has PF05591, Protein of unknown function (DUF770);IPR008312,UCP028301;This family consists of several proteins of unknown function from various bacterial species. These proteins are encoded in pathogenic and symbiotic bacteria as part of an operon (part of the SCI genomic island in Salmonella enterica and the imp locus in Rhizobium leguminosarum) implicated in pathogenicity and protein secretion.These proteins are SciH/ImpB.; High confidence in function and specificity
YP_935398.1	Putative cytoplasmic protein, sciI, 68% identity(80% similarity) to TrEMBL;Q93IS7. Has PF05943,Protein of unknown function (DUF877);IPR010269;This family consists of a number of uncharacterised bacterial proteins. The function of this family is unknown.; High confidence in function and specificity
YP_935399.1	Putative cytoplasmic protein,sciM , 33% identity(50% similarity) to TrEMBL;Q7AXY8. Has PF05638,Protein of unknown function (DUF796);IPR008514;This family consists of several bacterial proteins of unknown function.; High confidence in function and specificity
YP_935400.1	Putative cytoplasmic protein,sciK, 33% identity to TrEMBL;Q7AXZ0. Has PF05638, Protein of unknown function (DUF796);This family consists of several bacterial proteins of unknown function. Signal Peptide or TMH absent.; Conserved hypothetical protein
YP_935401.1	Putative cytoplasmic protein,sciE, 37% identity(52% similarity) to TrEMBL;Q93IT1. Has PF07024, ImpE protein;This family consists of several bacterial proteins including ImpE (Q93EC9) from Rhizobium leguminosarum. It has been suggested that the imp locus is involved in the secretion to the environment of proteins, including periplasmic RbsB protein, that cause blocking of infection specifically in pea plants.The exact function of this family is unknown.; High confidence in function and specificity
YP_935402.1	Putative cytoplasmic protein, sciD,34% identity (50% similarity) to TrEMBL; Q7AXZ4. Has PF07025, Protein of unknown function (DUF1316);IPR010745;This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown.; Conserved hypothetical protein
YP_935403.1	Putative cytoplasmic protein, sciC, 42% identity (57% similarity) to TrEMBL; Q93IT3. Has PF05947, Bacterial protein of unknown function (DUF879);IPR010272 ; This family consists of several hypothetical bacterial proteins of unknown function.; Function unclear
YP_935404.1	Putative cytoplasmic protein, sciB. TrEMBl;Q93IT4(36% identity) Has PF06996;Protein of unknown function (DUF1305);IPR010732 ;This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence.; Conserved hypothetical protein
YP_935405.1	Putative ATP-dependent Clp protease, ATP-binding subunit ClpB. Homology to clpB of E. coli of 38% (sprot|CLPB_ECOLI). The protein is thought to be subunits of ATP-dependent proteases which act as chaperones to target the proteases to substrates. Pfam: ATPsae family associated with various cellular activites no signal peptide no TMHs; High confidence in function and specificity
YP_935406.1	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank no domains predicted no signal peptide no TMHs
YP_935407.1	Entry name:- TREMBL:Q7MFV5 Identities = 112/345 (32%), InterPro:- IPR002921; Lipase_3. Pfam:- PF01764; Lipase_3; 1. Prediction: Non-secretory protein Signal peptide probability: 0.074 Number of predicted TMHs: 0; Family membership
YP_935408.1	Hypothetical protein. No homology over the entire length with the data base. Pfam: Phosphatidylinositol-specific phospholipase C, X domain. Interpro: Phosphatidylinositol-specific phospholipase C, X region (IPR000909). No TMHs. No signal peptide.
YP_935409.1	Conserved hypothetical protein. Homology to xac4125 of X. axonopodis of 42% (trembl|Q8PF60). Domain structure: 5 x TRP, 50 aa - 83 aa; 84 aa - 117 aa; 118 aa - 151 aa; 152 aa - 182 aa; 186 aa - 219 aa. InterPro: TPR repeat (IPR001440); SAM (and some other nucleotide) binding motif (IPR000051). Pfam: TPR daomian. no signal peptide. no TMHs
YP_935410.1	PutativeSerine/threonine-protein kinase (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine protein kinase 2). Seems to act exclusively upon threonine residues. Pfam: Protein kinase domain; Family membership
YP_935411.1	Probable sensor protein,; High confidence in function and specificity
YP_935412.1	Hypothetical secreted protein no homology of the entire protein to the data bank no domains predicted signal peptide no TMHs
YP_935413.1	FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_935414.1	Conserved hypothetical protein. Homology to RSc0426 of R.solanacearum of 51% (trembl:Q8Y2B0). No domains predicted. No signal peptide. No TMHs.
YP_935415.1	Entry name:- TREMBL:Q8Y2B1 Prim. accession # Q8Y2B1 Identities = 64/116 (55%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0
YP_935416.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_935417.1	23% K_eff.IPR006153; Na_H_porter. Pfam:PF00999; Na_H_Exchanger; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix: 11.; High confidence in function and specificity
YP_935418.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis
YP_935419.1	Specificity unclear
YP_935420.1	Putative phospholipid biosynthesis acyltransferase,30% Identity to TrEMBL;Q8FJ00.Q8X6N6 Has Signal Peptide. Has SMART;SM00563, PlsC, Phosphate acyltransferases;Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
YP_935421.1	MltA-interacting protein precursor. MAY SERVE AS A SCAFFOLD PROTEIN REQUIRED FOR THE FORMATION OF A COMPLEX WITH MRCB/PONB AND MLTA THIS COMPLEX COULD PLAY A ROLE IN ENLARGEMENT AND SEPTATION OF THE MUREIN SACCULUS.; High confidence in function and specificity
YP_935422.1	Conserved Hypothetical protein, Most Hits in the data base suggest to Pteridine-dependent deoxygenase like protein,TrEMBL;Q8P3Q5. Has PF01042 Endoribonuclease L-PSP,(IPR006175:Endoribon_LPSP);This domain is found in endoribonuclease, that is active on single-stranded mRNA and inhibits protein synthesis by cleavage of mRNA. Previously it was thought to inhibit protein synthesis initiation.This endoribonuclease may also be involved in the regulation of purine biosynthesis . No Signal peptide or TMH present!; Family membership
YP_935423.1	Conserved hypothetical protein. Homology to xcc4013 of X. campestris of 46% (trembl|Q8P3Q6). InterPro: Monooxygenases FAD binding domain (IPR002938); NAD binding site (IPR000205) Pfam: FAD binding domain; Monooxygenase FAD binding domain. no signal peptide. no TMHs
YP_935424.1	Conserved hypothetical secred protein. Homology to xac4267 of X. axonopodis of 41% (trembl|Q8PES3). no domains predicted .signal peptide. no TMHs; Conserved hypothetical protein
YP_935425.1	Probable leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (49% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity
YP_935426.1	catalyzes the oxidative deamination of D-amino acids
YP_935427.1	Alanine racemase catabolic (EC 5.1.1.1). Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by dadA (By similarity). alr: alanine racemase; High confidence in function and specificity
YP_935428.1	conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH
YP_935429.1	Conserved hyppthetical cytochrome c-type biogenesis protein CycH. Homology to cycH of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebA3526(KEGG)). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE (BY SIMILARITY). signal peptide. 1 TMHs; Conserved hypothetical protein
YP_935430.1	Probable Cytochrome c-type biogenesis protein cycL. Homology to cycL of S. meliloti of 44% (sprot|CCMH_RHIME). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE. signal peptide probable 2 TMHs; Family membership
YP_935431.1	Probable thiol disulfide interchange protein. Involved in disulfide bond formation. Catalyzes a late reductive step in the assembly of periplasmic c-type cytochromes probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity). InterPro: Periplasmic protein thiol:disulfide oxidoreductase DsbE (IPR004799) Interpro: Thioredoxin (IPR006662) Tigrfam: dsbE: periplasmic protein thiol:disulfide axidoreductase, DsbE superfamily signal peptide Probable 1 TMH; Family membership
YP_935432.1	Cytochrome c-type biogenesis protein ccmF. Homology to ccmF of E. coli of 63% (sprot|CCMF_ECOLI). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE. Tigrfam: nerF: cytochrome c-type biogenesis protein ccmF Pfam: Cytochrome C assembly protein probably signal peptide probably 15 THMs; High confidence in function and specificity
YP_935433.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane
YP_935434.1	Conserved hypothetical heme exporter protein D. Homology to ccmD of Azoarcus EBN1 of 49% (trembl:Q5P3K7). Pfam: Heme exporter protein D . The CcmD protein is part of a C-type cytochrome biogenesis operon. The exact function of this protein is uncertain. It has been proposed that CcmC, CcmD and CcmE interact directly with each other, establishing a cytoplasm to periplasm haem delivery pathway for cytochrome c maturation. This protein is found fused to CcmE in P52224. These proteins contain a predicted transmembrane helix. No signal peptide. 1 TMHs; Conserved hypothetical protein
YP_935435.1	Probable heme exporter protein C (Cytochrome c-type biogenesis protein ccmC). Homology to ccmC of E. coli of 43% (sprot|CCMC_ECOLI). Required for the export of heme to the periplasm for the biogenesis of C-type cytochromes. Pfam: Cytrochrome C assembly protein no signal peptide probable 6 TMHs; High confidence in function and specificity
YP_935436.1	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs
YP_935437.1	Probable heme exporter protein B (Cytochrome c-type biogenesis protein ccmB). Homology to ccmB (sprot|CCMB_ECOLI) of E. coli of 49%. Required for the export of heme to the periplasm for the biogenesis of C-type cytochromes (By similarity). no signal peptide probable 6 TMHs; High confidence in function and specificity
YP_935438.1	ATP-binding protein; required for proper cytochrome c maturation
YP_935439.1	Putative aerotaxis receptor, sensory_box TMHMM reporting 2 transmembrane helices. HTH reporting nucleic acid binding motif. Aerotaxis receptor. SIGNAL TRANSDUCER FOR AEROTAXIS. THE AEROTACTIC RESPONSES IS THE ACCUMULATION OF CELLS AROUND AIR BUBBLES. THE NATURE OF THE SENSORY STIMULUS DETECTED BY THIS PROTEIN IS THE PROTON MOTIVE FORCE OR CELLULAR REDOX STATE. IT USES A FAD PROSTHETIC GROUP AS A REDOX SENSOR TO MONITOR OXYGEN LEVELS.; Specificity unclear
YP_935440.1	Probable cytochrome c-type protein NapC. Homology to napC of R. sphaeroides of 57% (sprot|NAPC_RHOSH). MEDIATES ELECTRON FLOW FROM QUINONES TO THE NAPAB COMPLEX. no signal peptide probable 1 TMHs; High confidence in function and specificity
YP_935441.1	Probable diheme cytochrome c. Homology to napB of A. eutrophus of 47% (sprot|NAPB_ALCEU). SMALL SUBUNIT OF THE PERIPLASMIC NITRATE REDUCTASE (NAP). ONLY EXPRESSED AT HIGH LEVELS DURING AEROBIC GROWTH. NAPAB COMPLEX RECEIVES ELECTRONS FROM THE MEMBRANE-ANCHORED TETRAHEME NAPC PROTEIN THUS ALLOWING ELECTRON FLOW BETWEEN MEMBRANE AND PERIPLASM. ESSENTIAL FUNCTION FOR NITRATE ASSIMILATION AND MAY HAVE A ROLE IN ANAEROBIC METABOLISM. signal peptide no TMHs; High confidence in function and specificity
YP_935442.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA
YP_935443.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway
YP_935444.1	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC
YP_935445.1	Probable NapD protein, 38% Identity to TrEMBL;Q6LTW0, Has PF03927, NapD protein;IPR005623;Uncharacterized protein involved in formation of periplasmic nitrate reductase.; Family membership
YP_935446.1	Probabel ferredoxin-type protein napF. Homology to napF of E. coli of 43% (sprot|NAPF_ECOLI). Involved in electron transfer ina a wide variety of metabolic reactions. InterPro: Ferredoxin-type protein NapF (IPR004496); 4Fe-4S ferredoxin, iron-sulfur binding domain (IPR001450) Tigrfam: napF: ferredoxin-type protein NapF Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity
YP_935447.1	Putative hybrid sensor and regulator protein,; Specificity unclear
YP_935448.1	Putative transcriptional regulator,; Function unclear
YP_935449.1	Putative two component sensor protein,; Function unclear
YP_935450.1	Excinuclease cho (EC 3.1.25.-) (Endonuclease cho) (UvrC homolog protein). Incises the DNA at the 3 side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5 site of a lesion. When a lesion remains because uvrC is not able to induce the 3 incision cho incises the DNA. Then uvrC makes the 5 incision. The combined action of cho and uvrC broadens the substrate range of nucleotide excision repair (By similarity).; Specificity unclear
YP_935451.1	Ubiquinone/menaquinone biosynthesis methyltransferase ubiE (EC 2.1.1.-). Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-14-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-14-benzoquinol (DMQH2) (By similarity). InterPro: ubiE/COQ5 methyltransferase rrmJ: ribosomal RNA large subunit methy; High confidence in function and specificity
YP_935452.1	Conserved hypothetical protein. Homology to RS02765 of R.solanacearum of 43% (trembl:Q8XWT5). No domains predicted. No TMHs. No signal peptide.
YP_935453.1	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase,; High confidence in function and specificity
YP_935454.1	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_935455.1	Essential for recycling GMP and indirectly, cGMP
YP_935456.1	Similar to TREMBL:Q9HXG0 (60% identity); TREMBL:Q7NRZ4 (45% identity); TREMBL:Q88GB8 (43% identity). InterPro (IPR000868): Isochorismatase hydrolase. Pfam (PF00857): Isochorismatase family.; Specificity unclear
YP_935457.1	Conserved hypothetical protein. Homology to Daro03000439 of Dechloromonas aromatica of 48% (gi|41725494|ref|ZP_00152252.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.
YP_935458.1	Conserved hypothetical protein, has weak homlogs in the Database. TrEMBL;Q88I83(25% Identity). gi|46140644|ref|ZP_00152253.2| , 30% Identity to Dechloromonas aromatica RCB,Nucleotidyltransferase/DNA polymerase involved in DNA repair Has PF00817,impB/mucB/samB family; IPR001126, UMUC_like; These proteins are involved in UV protection.In Escherichia coli, UV and many chemicals appear to cause mutagenesis by a process of translesion synthesis that requires DNA polymerase III and the SOS-regulated proteins UmuD, UmuC and RecA. This machinery allows the replication to continue through DNA lesion, and therefore avoid lethal interruption of DNA replication after DNA damage. The UmuC is a well conserved protein in prokaryotes, with a homologue in yeast.
YP_935459.1	Region start changed from 4336170 to 4337262 (-1092 bases)
YP_935460.1	Carboxymuconolactone decarboxylase family protein,65% Identity (78% similarity) to TrEMBL;Q8EKK9. Has PF02627, Carboxymuconolactone decarboxylase family; IPR003779, CMD: Carboxymuconolactone decarboxylase (CMD)is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins (e.g. O67982) CMD represents the C-terminal domain, Abhydrolase_1 represents the N-terminal domain.; High confidence in function and specificity
YP_935461.1	Putative MerR-family transcriptional regulator,; Family membership
YP_935462.1	Putative alpha helix protein,yicC.42% identity(57% Similarity) to SwissProt;P23839, TrEMBL;Q8XD97(42%). TrEMBL; Q8XXF8(45% identity). Coils2 program reports the presence of Coiled-Coil. Has PF03755, YicC-like family, N-terminal region; IPR005229, Cons_hypoth255: Family of bacterial proteins. Although poorly characterised, the members of this protein family have been demonstrated to play a role in stationary phase survival. These proteins are not essential during stationary phase.; Conserved hypothetical protein
YP_935463.1	Putative serine/threonine protein kinase,; Family membership
YP_935464.1	Putative phosphoprotein phosphatase,; Conserved hypothetical protein
YP_935465.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_935466.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_935467.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_935468.1	Hypothetical protein predicted by Glimmer/Critica. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. No TMHs
YP_935469.1	Putative protease IV. homology to sspA of E. coli of 38% (sprot|SPPA_ECOLI). Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane. InterPro: Signal peptide peptidase SppA 67K type (IPR004634); Signal peptide peptidase SppA 36K type (IPR004635); Pepditase family U7 (IPR002142) Pfam: Peptidase family U7 Tigrfam: SppA_67K: signal peptide peptidase SppA; sppA_dom: signal peptide peptidase SppA no signal peptide probable 1 TMH; High confidence in function and specificity
YP_935470.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_935471.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_935472.1	Putative sulfur transfer protein involved in thimanin biosynsthesis.; High confidence in function and specificity
YP_935473.1	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine
YP_935474.1	Q8YDE4:20% identity, 37% similarity. Ubiquinone/menaquinone biosynthesis methyltransferase ubiE . Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-14-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-14-benzoquinol (DMQH2) (By similarity). METHIONINE BIOSYNTHESIS PROTEIN Pfam:PPTA(protein prenyl transferase alpha subunit), FERM domain TIGRFAM:rmJ: ribosomal RNA large subunit methylation InterPro IPR000051; SAM_bind. IPR004034; Ubi/men_Metransf. IPR004033; UbiE/COQ5_Metrf. HTH predicted nucleic acid binding motif PROSITE PS01183; UBIE_1; 1. PS01184; UBIE_2; FALSE_NEG.; Family membership
YP_935475.1	Hypothetical protein. no homology of the entire protein to the data bank. Pfam: putative peptidoglycan binding domain. This domain, peptidoglycan binding domain 1, may have a general peptidoglycan binding function. It is composed of three alpha helices and is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. no signal peptide. no TMHs
YP_935476.1	Conserved hypothetical protein. Homology to bb4936 of B. bronchiseptica of 36% (trembl|Q7WDQ2). no domains predicted. no signal peptide. no TMHs
YP_935477.1	AmpG protein. Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling.Belong to the BT1 family of proteins. Presence of DUF domains and signail peptide. 11 tranmembrane helices.36% identity and 50% similarity to E.coli AmpG protein.(JW0423) 2A0125: AmpG-related permease; Family membership
YP_935478.1	Probable uracil-DNA glycosylase. Has PF03167,Uracil DNA glycosylase superfamily;IPR005122 UDNA_glycsylseSF; Uracil-DNA glycosylase is a DNA repair enzyme that excises uracil residues from DNA by cleaving the N-glycosylic bond. Uracil in DNA can arise as a result of misincorportation of dUMP residues by DNA polymerase or deamination of cytosine. The sequence of uracil-DNA glycosylase is extremely well conserved
YP_935479.1	Region start changed from 4356747 to 4357095 (-348 bases)
YP_935480.1	Primosomal protein N (Replication factor Y). Recognizes a specific hairpin sequence on phiX ssDNA. This structure is then recognized and bound by proteins priB and priC. Formation of the primosome proceeds with the subsequent actions of dnaB dnaC dnaT and primase. PriA then functions as a helicase within the primosome. InterPro: DEAD/DEAH box helicase; High confidence in function and specificity
YP_935481.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_935482.1	This proteins are involved in active potassium uptake utilising ATP in the process. TrkH a member of the family TRKH is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.Requires TrkE for transport activity. 38% Cat_transpt.IPR004772; K_transptTrk. Pfam:PF02386; TrkH; 1. TIGRFAMs:TIGR00933; 2a38; 1. TMHelix:10. Signal peptide present.; High confidence in function and specificity
YP_935483.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
YP_935484.1	Probable nitrogen assimilation regulatory protein,; High confidence in function and specificity
YP_935485.1	Probable nitrogen regulation protein,; High confidence in function and specificity
YP_935486.1	Conserved hypothetical secreted protein. Homology to RS02253 of R.solanacearum of 32% (trembl|Q8Y3A4(SRS)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein
YP_935487.1	SUN protein; Conserved hypothetical protein
YP_935488.1	Spermidine synthase counts to a group of polyamine biosynthetic enzymes involved in the fifth (last) step in the biosynthesis of spermidine from arginine and methionine which includes; spermidine synthase, spermine synthase and putrescine N-methyltransferase. Similar to sprot|SPEE_NITEU (39%) and to sprot|SPE1_PSEAE (34%). ProSite (PS50193): SAM (and some other nucleotide) binding motif Pfam (PF01564): Spermidine synthase TIGRFAM: speE,spermidine synthase; Specificity unclear
YP_935489.1	Conserved hypothetical membrane protein. TREMBL:Q88FZ3: 44% identity, 60% similarity InterPro:IPR002781; DUF81.This domain is found in integral membrane proteins of prokaryotes which are uncharacterized Pfam:PF01925; DUF81 Signal peptide present and presence of 6 transmembrane helices.; Conserved hypothetical protein
YP_935490.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_935491.1	Inner membrane protein oxaA. Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex (by similariety). Pfam: 60 kd inner membran proetin TMHs: 3 Signal peptide: no; High confidence in function and specificity
YP_935492.1	Conserved hypothetical protein, 62% identical(76% similar) to SwissProt;Q7NPT7. Has PF01809, Domain of unknown function DUF37;IPR002696;This domain is found in short (70 amino acid) hypothetical proteins from various bacteria. The domain contains three conserved cysteine residues. Q44066 from Aeromonas hydrophila has been found to have hemolytic activity (unpublished).
YP_935493.1	Region start changed from 4375477 to 4375591 (114 bases)
YP_935494.1	Putative Ribosomal protein L34. Has PF00468,Ribosomal protein L34;IPR000271, Ribosomal_L34;Ribosomes are the particles that catalyze mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites.; Function unclear